LOCUS       DADVXM010000001       131739 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.001, whole genome shotgun sequence.
ACCESSION   DADVXM010000001 DADVXM010000000
VERSION     DADVXM010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 131739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 131739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..131739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.001"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(150..2336)
                     /locus_tag="KB927_000001"
     CDS             complement(150..2336)
                     /locus_tag="KB927_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBB6838956.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNISVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            2554..3237
                     /locus_tag="KB927_000002"
     CDS             2554..3237
                     /locus_tag="KB927_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBB6838957.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(3318..4037)
                     /locus_tag="KB927_000003"
     CDS             complement(3318..4037)
                     /locus_tag="KB927_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6838958.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4349..4555)
                     /locus_tag="KB927_000004"
     CDS             complement(4349..4555)
                     /locus_tag="KB927_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838959.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            4800..5402
                     /locus_tag="KB927_000005"
     CDS             4800..5402
                     /locus_tag="KB927_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBB6838960.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            5543..6823
                     /locus_tag="KB927_000006"
     CDS             5543..6823
                     /locus_tag="KB927_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6838961.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            6836..7564
                     /locus_tag="KB927_000007"
     CDS             6836..7564
                     /locus_tag="KB927_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6838962.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(7633..9156)
                     /locus_tag="KB927_000008"
     CDS             complement(7633..9156)
                     /locus_tag="KB927_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBB6838963.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            9408..10589
                     /locus_tag="KB927_000009"
     CDS             9408..10589
                     /locus_tag="KB927_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6838964.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(10649..12277)
                     /gene="treC"
                     /locus_tag="KB927_000010"
     CDS             complement(10649..12277)
                     /gene="treC"
                     /locus_tag="KB927_000010"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBB6838965.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12728..15439)
                     /locus_tag="KB927_000011"
     CDS             complement(12728..15439)
                     /locus_tag="KB927_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6838966.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGTIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(15449..16150)
                     /locus_tag="KB927_000012"
     CDS             complement(15449..16150)
                     /locus_tag="KB927_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838967.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            16336..16935
                     /locus_tag="KB927_000013"
     CDS             16336..16935
                     /locus_tag="KB927_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6838968.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            17016..18029
                     /locus_tag="KB927_000014"
     CDS             17016..18029
                     /locus_tag="KB927_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBB6838969.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            18137..19054
                     /gene="rbsK"
                     /locus_tag="KB927_000015"
     CDS             18137..19054
                     /gene="rbsK"
                     /locus_tag="KB927_000015"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBB6838970.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            19082..19477
                     /gene="rbsD"
                     /locus_tag="KB927_000016"
     CDS             19082..19477
                     /gene="rbsD"
                     /locus_tag="KB927_000016"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBB6838971.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            19477..20850
                     /locus_tag="KB927_000017"
     CDS             19477..20850
                     /locus_tag="KB927_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6838972.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            21207..23351
                     /locus_tag="KB927_000018"
     CDS             21207..23351
                     /locus_tag="KB927_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6838973.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(23403..24443)
                     /locus_tag="KB927_000019"
     CDS             complement(23403..24443)
                     /locus_tag="KB927_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6838974.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(24720..26522)
                     /locus_tag="KB927_000020"
     CDS             complement(24720..26522)
                     /locus_tag="KB927_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6838975.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(26536..27288)
                     /locus_tag="KB927_000021"
     CDS             complement(26536..27288)
                     /locus_tag="KB927_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838976.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(27297..27659)
                     /locus_tag="KB927_000022"
     CDS             complement(27297..27659)
                     /locus_tag="KB927_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6838977.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(27835..28707)
                     /locus_tag="KB927_000023"
     CDS             complement(27835..28707)
                     /locus_tag="KB927_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBB6838978.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(28758..29246)
                     /locus_tag="KB927_000024"
     CDS             complement(28758..29246)
                     /locus_tag="KB927_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBB6838979.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(29384..30175)
                     /locus_tag="KB927_000025"
     CDS             complement(29384..30175)
                     /locus_tag="KB927_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBB6838980.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(30230..30838)
                     /locus_tag="KB927_000026"
     CDS             complement(30230..30838)
                     /locus_tag="KB927_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBB6838981.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(30831..31148)
                     /locus_tag="KB927_000027"
     CDS             complement(30831..31148)
                     /locus_tag="KB927_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6838982.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(31304..32032)
                     /locus_tag="KB927_000028"
     CDS             complement(31304..32032)
                     /locus_tag="KB927_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBB6838983.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            32191..33072
                     /locus_tag="KB927_000029"
     CDS             32191..33072
                     /locus_tag="KB927_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6838984.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(33309..34352)
                     /locus_tag="KB927_000030"
     CDS             complement(33309..34352)
                     /locus_tag="KB927_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6838985.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(34355..35023)
                     /locus_tag="KB927_000031"
     CDS             complement(34355..35023)
                     /locus_tag="KB927_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6838986.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            35165..37501
                     /locus_tag="KB927_000032"
     CDS             35165..37501
                     /locus_tag="KB927_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6838987.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(37616..37927)
                     /locus_tag="KB927_000033"
     CDS             complement(37616..37927)
                     /locus_tag="KB927_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838988.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            38108..39583
                     /locus_tag="KB927_000034"
     CDS             38108..39583
                     /locus_tag="KB927_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBB6838989.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPTMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            39630..40214
                     /locus_tag="KB927_000035"
     CDS             39630..40214
                     /locus_tag="KB927_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBB6838990.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            40216..40635
                     /locus_tag="KB927_000036"
     CDS             40216..40635
                     /locus_tag="KB927_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBB6838991.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(40916..41200)
                     /locus_tag="KB927_000037"
     CDS             complement(40916..41200)
                     /locus_tag="KB927_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBB6838992.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(41552..42262)
                     /locus_tag="KB927_000038"
     CDS             complement(41552..42262)
                     /locus_tag="KB927_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBB6838993.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(42259..43731)
                     /locus_tag="KB927_000039"
     CDS             complement(42259..43731)
                     /locus_tag="KB927_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6838994.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            43869..44342
                     /locus_tag="KB927_000040"
     CDS             43869..44342
                     /locus_tag="KB927_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6838995.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(44495..45046)
                     /locus_tag="KB927_000041"
     CDS             complement(44495..45046)
                     /locus_tag="KB927_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6838996.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            45151..45681
                     /locus_tag="KB927_000042"
     CDS             45151..45681
                     /locus_tag="KB927_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBB6838997.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(46164..46607)
                     /locus_tag="KB927_000043"
     CDS             complement(46164..46607)
                     /locus_tag="KB927_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6838998.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(46623..47783)
                     /locus_tag="KB927_000044"
     CDS             complement(46623..47783)
                     /locus_tag="KB927_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6838999.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            48290..49990
                     /locus_tag="KB927_000045"
     CDS             48290..49990
                     /locus_tag="KB927_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839000.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(50092..50925)
                     /locus_tag="KB927_000046"
     CDS             complement(50092..50925)
                     /locus_tag="KB927_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBB6839001.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(51229..53394)
                     /locus_tag="KB927_000047"
     CDS             complement(51229..53394)
                     /locus_tag="KB927_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6839002.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            53654..55948
                     /locus_tag="KB927_000048"
     CDS             53654..55948
                     /locus_tag="KB927_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBB6839003.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            55941..56606
                     /gene="pgmB"
                     /locus_tag="KB927_000049"
     CDS             55941..56606
                     /gene="pgmB"
                     /locus_tag="KB927_000049"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBB6839004.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            56599..57606
                     /locus_tag="KB927_000050"
     CDS             56599..57606
                     /locus_tag="KB927_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6839005.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            57628..58647
                     /locus_tag="KB927_000051"
     CDS             57628..58647
                     /locus_tag="KB927_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6839006.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(58928..60295)
                     /gene="nhaC"
                     /locus_tag="KB927_000052"
     CDS             complement(58928..60295)
                     /gene="nhaC"
                     /locus_tag="KB927_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBB6839007.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(60404..61825)
                     /locus_tag="KB927_000053"
     CDS             complement(60404..61825)
                     /locus_tag="KB927_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6839008.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(62068..63945)
                     /gene="tdc"
                     /locus_tag="KB927_000054"
     CDS             complement(62068..63945)
                     /gene="tdc"
                     /locus_tag="KB927_000054"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBB6839009.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(64236..65492)
                     /locus_tag="KB927_000055"
     CDS             complement(64236..65492)
                     /locus_tag="KB927_000055"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBB6839010.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(65604..65809)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            66072..67373
                     /locus_tag="KB927_000056"
     CDS             66072..67373
                     /locus_tag="KB927_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBB6839011.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(67442..68041)
                     /locus_tag="KB927_000057"
     CDS             complement(67442..68041)
                     /locus_tag="KB927_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6839012.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            68295..69176
                     /locus_tag="KB927_000058"
     CDS             68295..69176
                     /locus_tag="KB927_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6839013.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            69189..70799
                     /locus_tag="KB927_000059"
     CDS             69189..70799
                     /locus_tag="KB927_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBB6839014.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(70876..71535)
                     /locus_tag="KB927_000060"
     CDS             complement(70876..71535)
                     /locus_tag="KB927_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6839015.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(71818..72483)
                     /locus_tag="KB927_000061"
     CDS             complement(71818..72483)
                     /locus_tag="KB927_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBB6839016.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(72630..73235)
                     /gene="dhaL"
                     /locus_tag="KB927_000062"
     CDS             complement(72630..73235)
                     /gene="dhaL"
                     /locus_tag="KB927_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBB6839017.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(73263..74273)
                     /gene="dhaK"
                     /locus_tag="KB927_000063"
     CDS             complement(73263..74273)
                     /gene="dhaK"
                     /locus_tag="KB927_000063"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBB6839018.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(74248..74694)
                     /gene="dhaM"
                     /locus_tag="KB927_000064"
     CDS             complement(74248..74694)
                     /gene="dhaM"
                     /locus_tag="KB927_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBB6839019.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            74797..75117
                     /locus_tag="KB927_000065"
     CDS             74797..75117
                     /locus_tag="KB927_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBB6839020.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(75229..76098)
                     /locus_tag="KB927_000066"
     CDS             complement(75229..76098)
                     /locus_tag="KB927_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6839021.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(76194..77498)
                     /locus_tag="KB927_000067"
     CDS             complement(76194..77498)
                     /locus_tag="KB927_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6839022.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(77495..78004)
                     /locus_tag="KB927_000068"
     CDS             complement(77495..78004)
                     /locus_tag="KB927_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839023.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(78179..80314)
                     /locus_tag="KB927_000069"
     CDS             complement(78179..80314)
                     /locus_tag="KB927_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6839024.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(80397..82052)
                     /locus_tag="KB927_000070"
     CDS             complement(80397..82052)
                     /locus_tag="KB927_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6839025.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(82054..82368)
                     /locus_tag="KB927_000071"
     CDS             complement(82054..82368)
                     /locus_tag="KB927_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6839026.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            82538..82798
                     /locus_tag="KB927_000072"
     CDS             82538..82798
                     /locus_tag="KB927_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBB6839027.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            82812..83126
                     /locus_tag="KB927_000073"
     CDS             82812..83126
                     /locus_tag="KB927_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBB6839028.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(83856..84410)
                     /locus_tag="KB927_000074"
     CDS             complement(83856..84410)
                     /locus_tag="KB927_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBB6839029.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(84536..86465)
                     /locus_tag="KB927_000075"
                     /pseudo
     CDS             complement(84536..86465)
                     /locus_tag="KB927_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(86771..87487)
                     /locus_tag="KB927_000076"
     CDS             complement(86771..87487)
                     /locus_tag="KB927_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBB6839030.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(87488..89311)
                     /gene="glpO"
                     /locus_tag="KB927_000077"
     CDS             complement(87488..89311)
                     /gene="glpO"
                     /locus_tag="KB927_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBB6839031.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(89325..90821)
                     /gene="glpK"
                     /locus_tag="KB927_000078"
     CDS             complement(89325..90821)
                     /gene="glpK"
                     /locus_tag="KB927_000078"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBB6839032.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(90957..92417)
                     /locus_tag="KB927_000079"
     CDS             complement(90957..92417)
                     /locus_tag="KB927_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6839033.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(92407..93702)
                     /locus_tag="KB927_000080"
     CDS             complement(92407..93702)
                     /locus_tag="KB927_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6839034.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(94034..94711)
                     /locus_tag="KB927_000081"
     CDS             complement(94034..94711)
                     /locus_tag="KB927_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBB6839035.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(94741..95832)
                     /locus_tag="KB927_000082"
     CDS             complement(94741..95832)
                     /locus_tag="KB927_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBB6839036.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(95933..96367)
                     /locus_tag="KB927_000083"
     CDS             complement(95933..96367)
                     /locus_tag="KB927_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6839037.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(96951..98408)
                     /gene="ascB"
                     /locus_tag="KB927_000084"
     CDS             complement(96951..98408)
                     /gene="ascB"
                     /locus_tag="KB927_000084"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6839038.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(98405..100300)
                     /locus_tag="KB927_000085"
     CDS             complement(98405..100300)
                     /locus_tag="KB927_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6839039.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(100358..102133)
                     /locus_tag="KB927_000086"
     CDS             complement(100358..102133)
                     /locus_tag="KB927_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBB6839040.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(102183..103679)
                     /locus_tag="KB927_000087"
     CDS             complement(102183..103679)
                     /locus_tag="KB927_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6839041.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(103873..105495)
                     /locus_tag="KB927_000088"
     CDS             complement(103873..105495)
                     /locus_tag="KB927_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBB6839042.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(105823..107136)
                     /locus_tag="KB927_000089"
     CDS             complement(105823..107136)
                     /locus_tag="KB927_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBB6839043.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(107381..107605)
                     /locus_tag="KB927_000090"
     CDS             complement(107381..107605)
                     /locus_tag="KB927_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839044.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(107625..108047)
                     /locus_tag="KB927_000091"
     CDS             complement(107625..108047)
                     /locus_tag="KB927_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBB6839045.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(108190..108900)
                     /locus_tag="KB927_000092"
     CDS             complement(108190..108900)
                     /locus_tag="KB927_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839046.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(108918..109415)
                     /locus_tag="KB927_000093"
     CDS             complement(108918..109415)
                     /locus_tag="KB927_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6839047.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(109452..109904)
                     /locus_tag="KB927_000094"
     CDS             complement(109452..109904)
                     /locus_tag="KB927_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6839048.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(110039..110644)
                     /locus_tag="KB927_000095"
     CDS             complement(110039..110644)
                     /locus_tag="KB927_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6839049.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(111094..111714)
                     /locus_tag="KB927_000096"
     CDS             complement(111094..111714)
                     /locus_tag="KB927_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6839050.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(111716..112585)
                     /locus_tag="KB927_000097"
     CDS             complement(111716..112585)
                     /locus_tag="KB927_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBB6839051.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(112608..113015)
                     /locus_tag="KB927_000098"
     CDS             complement(112608..113015)
                     /locus_tag="KB927_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBB6839052.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(113034..114323)
                     /locus_tag="KB927_000099"
     CDS             complement(113034..114323)
                     /locus_tag="KB927_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6839053.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGDFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(114350..114652)
                     /locus_tag="KB927_000100"
     CDS             complement(114350..114652)
                     /locus_tag="KB927_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6839054.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(114677..116770)
                     /locus_tag="KB927_000101"
     CDS             complement(114677..116770)
                     /locus_tag="KB927_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6839055.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(117259..118023)
                     /locus_tag="KB927_000102"
     CDS             complement(117259..118023)
                     /locus_tag="KB927_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBB6839056.1"
                     /translation="MKKINYLAIILLVGLCLFALPPQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(118134..119003)
                     /gene="mdcB"
                     /locus_tag="KB927_000103"
     CDS             complement(118134..119003)
                     /gene="mdcB"
                     /locus_tag="KB927_000103"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBB6839057.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(119028..120104)
                     /locus_tag="KB927_000104"
     CDS             complement(119028..120104)
                     /locus_tag="KB927_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBB6839058.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(120128..120721)
                     /locus_tag="KB927_000105"
     CDS             complement(120128..120721)
                     /locus_tag="KB927_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBB6839059.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(120725..122401)
                     /gene="mdcD"
                     /locus_tag="KB927_000106"
     CDS             complement(120725..122401)
                     /gene="mdcD"
                     /locus_tag="KB927_000106"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBB6839060.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(122391..122690)
                     /locus_tag="KB927_000107"
     CDS             complement(122391..122690)
                     /locus_tag="KB927_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBB6839061.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(122792..124438)
                     /gene="mdcA"
                     /locus_tag="KB927_000108"
     CDS             complement(122792..124438)
                     /gene="mdcA"
                     /locus_tag="KB927_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HBB6839062.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(124445..125356)
                     /locus_tag="KB927_000109"
     CDS             complement(124445..125356)
                     /locus_tag="KB927_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBB6839063.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            125476..126333
                     /locus_tag="KB927_000110"
     CDS             125476..126333
                     /locus_tag="KB927_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6839064.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(126520..126882)
                     /locus_tag="KB927_000111"
     CDS             complement(126520..126882)
                     /locus_tag="KB927_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBB6839065.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            127228..128667
                     /locus_tag="KB927_000112"
     CDS             127228..128667
                     /locus_tag="KB927_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6839066.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(128674..131226)
                     /locus_tag="KB927_000113"
     CDS             complement(128674..131226)
                     /locus_tag="KB927_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBB6839067.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(131340..>131739)
                     /locus_tag="KB927_000114"
     CDS             complement(131340..>131739)
                     /locus_tag="KB927_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6839068.1"
                     /translation="KEKSLPHWFCALSKKGVPLHGILITGMLFFAGLCLHFFVADSRL
                     FFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQRYKDLALLVFFTSIAFSLLFE
                     STTRFIPFLLVIWFVFLNFVYKRISNRNIS"
BASE COUNT        38375 a        27357 c        23028 g        42979 t
ORIGIN      
        1 ttgtcacacc tcccttttcc gaataaactg tgttccagaa atagcttctt cgaaaataag
       61 ctgaaatttc acaaaaattt gagaagcaat tttcgtacat tccttcttct ttcttgaaac
      121 tgaccacttc tgtcacaccc tctcttctat cactttcctt ttttcacacg actcccggtt
      181 tctttgataa atctcgatac tttcaatttt cttgaatttt tcatttgagg tacacataga
      241 tacagacgat ttcttgctct agtcatcgca acataaaata gtcttcgttc ttcttctatc
      301 gtcgttactg gttctgcttt tatttcatta aagtcgatta ctttcttttc tgtcgctccg
      361 ttataaggca aacttccttc gttacaacca atcaaaaaga catttcggta actaagacct
      421 ttacttttgt gaatgctctg gatacatagt gcatcaagtt ttccttgtct gtaagcaatc
      481 aagcgggttt ttaattcttt agctgtcgct tgggtttctt gcgataaggc ttggagtctt
      541 ctgaaagtag catgctgctt tacttcttct cgtatccatt cttgatcact ctggtcgatt
      601 tccttagcta tacgtggcag atgaagatag ctttgaacaa gcgaatagat ttcttgatgc
      661 tggtctgttt tacgcaacgc ttcctcaaac tctcggattt ctgcagattt cgattttaaa
      721 ttggggctta tcgacaaaat ataatctgca acggatatat tttgatattt aggagaaaag
      781 tattgatcgc attcactttt tttcaggtag cagtctgcca tcagctgccg gagcaattgc
      841 tggtaggcct gatttttctt ttgcagattc agtgctgttt gccaatgaac aattttttga
      901 tagaaatgtt ggaaagactt gataccaaag ataccttcat atggactatc tgcttccagt
      961 acaaaaggaa tattcgtttt cagcagagat tggacaagct gctgcgtttg tgaagctgat
     1021 cggtataata tgattgattc cttatatttc ccattttttt gaataaatgt ctgaatttgt
     1081 ttgattagcc actgactttc tgctttagta tcagaaaaca aataggcttc cataacacct
     1141 gcttcttttt gtgctggaat catcgccttt ggtatccgat catttttatt atagctgatc
     1201 aatctatttg ctccttggac aatagctgcc cgagaacgat aattagttaa taagaaaaga
     1261 gttttggtag gatattcttt ttcaaagttc ttgatgtatg ctggctctga tcctctgaat
     1321 ccatagatac tctgatcatc atctccaaca acaatcaact tgatcctgtt ttcctttgtc
     1381 atccgtttca cgatttccca ttgaagtgga ttagtatctt gaaattcatc aatgaataga
     1441 taatcatatt tttggccgat ataatgctgg atctcctcat tctccaaagc gcttttcaga
     1501 ttttggagta catcattgaa ctctagcaat tgctggcttc ttttttgttc ttggagttcc
     1561 gtgagcaatc catacagtcg ttctgatatc ggctgtcgtg cattcttatc aatggaatca
     1621 tatttttctt taactaactg aaccatttct tctactgaaa ggttcatatt ctgccaatag
     1681 tctaaccgag aagcaatcgt tttttctcca tattgatcaa atatataaag attatattta
     1741 cgtatcagct gttgcaaaac agcattcact ttttgtgcag tatcctttga aaagtctcct
     1801 tgtattcctt gcattgctac ttcaggaaat tttcgacaaa tttcattgta tatcctaaaa
     1861 aagatactat ggaatgttcc gatatggaca gcggtttttc tctggctgaa attatctact
     1921 cgttttttta gttcatttgc agcgttcctt gtaaaagtga tcattagtat gcgttcttcg
     1981 tctacttgtt tttgcgtcat cagataaaca gcttttgcac agattgtttg cgttttgccg
     2041 ctcccagctc ctgctatgat tcgaagatgt ttcttcatat catatgtgat agctgctttt
     2101 tgttcttgat tgaagcgatt ataggaacgt ttctccatca ttttaaagaa agagctgttt
     2161 ccttcacttt cttttacttg tacttcttcc tcaataagtc cgggtgcttc gccataagcc
     2221 gcttcatagg tagcaatgat ttcttcttgt agccgaaaga cttgttgaag ctttttatac
     2281 ttgttctccc agcgtttcaa ttctttttgt aatcggagaa tttctttttc attcaactga
     2341 ttgatttcct tcccatcttt cttctttgaa tttgtttatt tcaagttggt tatttaaagt
     2401 ttcgttgtct attttttctt tatactaaca gacctttcta aaaatgaaaa tgggaagcga
     2461 tatgatttta gttttctgaa aatttttcct ttttttcaat cgtttatgct aagataagga
     2521 agacaaaaat attcataaaa ggtgatgaaa aaaatgcaga cttcctttca cgaggggcgt
     2581 acaataggac ttttgctgac atttatcgga ggagccatgg acagttatac ttatatccaa
     2641 tatggtgctt ttgcctctgc tcaaactggc aatatcattc tatcgatcat ccaagcattt
     2701 gacggagaat ggctaagtgt tggtaaaaaa gtattgtcta cccttttctt tttcttaggg
     2761 attcttctaa caaagtatct aattgattat tttagaaaaa aagaaaaaca tttctggcgc
     2821 ttgtttgttc tatattatga agcagtgatt tttttctttg ttagtttgac acccgtccat
     2881 gagcatcccg cattagtaac gattttgatt gcttttactg catcgatcca gtgggtagct
     2941 tttgataaaa tcaacgggcg tgcctacact aatttattta caactggaaa tttaaaaggg
     3001 gtagcaacga acttatatga ttattgtatt tctaaagaaa aagcagattt tgatcgattt
     3061 ttccactatc taagtgtcgt tcttgccttt atcgcaggag ctattgtcct tgttttctgt
     3121 catcatctgt ttggcgccca ttcgattttg atcgtttcca ttttattttt gatcatggcc
     3181 ctcactcaga catttcattt atggcaattt tatcatacga atcggttcac tatttgatct
     3241 caatgaatca aaaaaactaa gcaagatgct gctcacagag aaatatctgc gagtgagcaa
     3301 tttgcttagt ttttatatta tttagttgta aagattccct ttgctttcgg gttatttgta
     3361 gtgtagcgga tcgactgggc atctgcctct tctgtcattt tctttgcccg catcttgatt
     3421 tcttgtacga tttgttctcc acatgccgga tcggctacga aatcatattt gtccccatcg
     3481 atcactattt tgggacatat atcaaactgt tcataccact cttcgtatcg tcgattgagt
     3541 tctttatagt aggaatagag ttcaggatct tgttctagct gttcatattc ccggcctctt
     3601 tttttgattc tcgctaacat agtttcaaag gatacacgaa tataaaccag tagatctggt
     3661 ttcttttgtg gcgaaatttc ttctaactcc ttcagcatcg tttctaaaag accttcatac
     3721 tgctttactt ctacttcaga aacacgccct aaatctgcat tcaaatgaaa cagcatacta
     3781 tcttcgtaga tggagcggtc tagtacgttg tcatcatggc tgaaagcatc tttgattgcc
     3841 aaaaagcgtt tgttcaaaaa gaaaatctgt aataaaaaag tatacttttc tggattagaa
     3901 taaaatagcg gcaatacttc attatcttcc acgttctcat aaaaaggttt tgtttctaaa
     3961 tcttgggcaa gcatttcagt tagtgtgctt ttccctgcac cgatcgttcc tgcaacaatg
     4021 atcacaatta tcggcatcct tcctgtaata aaatctgttc ttcattttac tacttcattt
     4081 atagaaataa aagccttgac tttatctgct ccttaaaagc tacttctcta aaagtagcca
     4141 aaagtaactc ctattcatga aaataaaggc tgtgacaaaa gtcttgtcgc agcccttttt
     4201 tcaaataaac agtattctcc tgccaacacc tcggtcacaa ggcaatattc ataaaacatg
     4261 aaaagctgtt ttttaacatt attccttgta actcagagct aaacgggaga ctcacaacct
     4321 ctttatgctc tcaacatttt atctgttttt attcttctat tgtacttgat ttgcgtacaa
     4381 ctaactgcca gtgcagatta tgagcggtat cattgtcttc tactgcgcat ttcatgacac
     4441 gtatcatcac actattttca tagatttttt ctatttttcc ttttattggt gattcaaata
     4501 aatcagattt aaatgcatat gtttcgccga cttcaaacaa ttgttcattt tccataagaa
     4561 tccctccatc accttttata aggtcagtaa ttttttaaca taaatcactc gaaaaagcac
     4621 aaacttgtca taaaaagtac ttttcgtatc aaaactgtca ctttttttgg taaggttctt
     4681 ggaaaacgaa gattttttta ggagatcatg acggttttga tgtcaaaacc actttttatg
     4741 aaacaaaaga cgttttttat tttttttagc ataaaatttg tggtggaggt acgtatgaga
     4801 tgaaagataa agttgtgaac aaattattag aagccttatt cagcggagac aaatcggaag
     4861 aagatatggt gtatgtccaa gtaaaatttg tcttagaagt tttattgaat aatcttggaa
     4921 aactagcggt cgttctagtc ttttctctgg tgacaggctc atgggcggaa acaggaatca
     4981 cctttctttc ttatatctgc atccgcagat atgcttatgg attgcattcc gactctgaat
     5041 tcgtttgtct gctgtggaca ctactttatt tatggggcgt tcccttggtg atgaaacatc
     5101 tgcaattgac tatctccttc ccaatgatgg tctttttgtt aatcagctgc tttttgttac
     5161 tgcttcgcta tggatcaaga ggtacagcaa tcaatcccat tgaacccgag aaacgtcccc
     5221 cattattaaa gaaggcgatc agcatgtttc taattttttc tctcattacg ttatttttct
     5281 cagcttctta cttttctacc tatttgctac ttgggattgt tttagaaata gctacgttgc
     5341 ttcctattac aaactacttg atgaattttg gaggaatctt tcatgaaaaa aacaatcatt
     5401 aaacaattaa ctaacttatc tgactttttt gtatctggct gctgctttgg tatgagttct
     5461 gaattcaaaa tccctgaaaa attaaaaaaa taatacgcca attgtgctat aatttggtaa
     5521 aaatcaatgg gagctgtact ttatgttttt atggtccata gcgttgcaat atttgattta
     5581 cacaatttgt atcttattga ttgaccatca catccgatac aaatatctgt ttgcgggagt
     5641 cattctgatt tcttgtattt tgattggatg ggtctattcg attttaggga tttttactgc
     5701 tctaattgct ataggaatgc tgatgcttac ttttttcttc ttttcgactt cgcgtcaaca
     5761 attggtttac gcgcttcctt ttgggttatt gacgtcgctt ttaggagatc acttaacaag
     5821 catcggcgat ttttttgttt tgaaatcttc ggttattgaa ccaggagatt cattgcagta
     5881 ttttcacatt gtcttatccg cttttttatc tgctttatta gctttttgtt taaaaaaatc
     5941 gttagagact tggtttcaca ctgtggaccg ccgtatgatc ggtacgatcg ggacattgat
     6001 attatttaca tactatatca ttatttttta tacccgtttt tctggtgaaa cacctgatgt
     6061 cttagctttg aatacgagtt ttttcattct atatctgtgt gttggcctga tcatcttggt
     6121 ttattattgg aaaatctcta ataagaaatt agctgatcag ttattagagc aacaagtcag
     6181 gatgcaacag gattatatca aagatctaga aaaaaactat caagacttga gagaattcaa
     6241 acatgattac caaaatctgc ttttttctct tcacagctat atttcagaag gcgacttaga
     6301 aggattacgg tcttattatg atcaaacgat attacctaca cgccagatga tgaacctttt
     6361 tccggccaat ctaagtatgt tggataatat gaaagttcct gagatccgta gtttactgtc
     6421 attaaaactc atgatggcac aggaaaaagg gttgatcgtc cagcttcatt ttcctgagcc
     6481 aatcgaactg gatacgaaac atacggtaaa ccttgtacgt atgcttggta ttatcttgga
     6541 caatgcgatt gaaggagcta gtgctgcaaa gaagaaaaaa atcgaattga ccatactcaa
     6601 gaagaatcat tccgtgatga ttcgtgtgat caatacaaca acaaatacat taccgttaaa
     6661 ccagttgaaa caaaaagggt tctcaacaaa aacaaatcca aaaaacgaag gccttggctt
     6721 gtttatcttg gatgaattga caaagaccaa tccttatctt ttccttgaaa catcaattga
     6781 aaaccagcgt ttttctcaaa cgatttatat acaaataaaa taaaggagta atgatatgat
     6841 tcccatttat atttgtgaag acgatccaaa acaattagaa gttttatcaa cggtgatcaa
     6901 aaatagaatc atgattgaaa acttagacag ttatgtccat atttctacct ctgatccgga
     6961 agaacttctc aatgcagcca agatcagaac ttcttctttt ggtatttact ttttagatat
     7021 cgaactagaa gacagtgaaa tggatggtgt agcgatcggt aaattgatcc gtgaattaga
     7081 tcctttagga aaaataatct atgtgacttc ccatacggaa atgtcgatga aaatcttaaa
     7141 aagcaacatc gaaccgactg attatatcgt caaagaagat ctttatgatt taaaagaaaa
     7201 tgtcgagcat atcctgagca aaattttcga agattttcaa atgtcccaaa tccaaaaaga
     7261 tatcttcaaa atagagttta atgatgagat caaattttta ccgatcaaag acatccaata
     7321 tttttctact tcgctaggag cgccacataa actggaagtc catttgactc atgcccaatt
     7381 acaattctat gagaagatca aagaaatcga gaaaatgcat cggaatttta tccgttgtca
     7441 taaatcctat gttatcaata cacaaaatgt gcggtcgatt aataaaaaaa ccagagaagt
     7501 cacgttggca aacggcgaga ccatcccagc ctctatccgt ggattaaaga aattgatttc
     7561 ataaaaagaa ccgaatagtt tggaccgact aaatgaccag ccgatccaaa cccttcggtt
     7621 cttttttgcc tatcagtgca aaagcatttc ctgtgcaatt tcacgtccat ccattgtatc
     7681 tggataaaat gttggccaat tctccatttc tttcagcaat acttcttgac tttcatttcc
     7741 tgcatataaa tgaaaatgtt cggagtcagc cggtgcaatc gtgtgatcac tgaattgaat
     7801 atatctaaaa gcgccacttt ccttatcttc tgcttcgaat agatacctta cgccacggtt
     7861 tcctgcctcg taggtcaaga tttctttccc tacataacga taatttgaac gtttcgttgt
     7921 tccattctta aacgtaaatg ccatctcttt ctcactgatc ttgattgaag caatatctgt
     7981 ttgatagccc ttcgtataat attctttata ttcttgtgct gtcttatcct gattcaattt
     8041 ttctttatat tcaaaaacag gatcaaaagt cccatcttct acatacgtat ctactgtttg
     8101 ccaagttcct gcccaatctg aaagagagcg atcttgtaca tcctcgtctt caaaataacc
     8161 gttgtagacg ctcttttctt ttttgggggt caaagtatct tctagcgggt tttctgtctc
     8221 tgtcgttttt ttcaacgctt cgaggtttgc ttccatgata gaaagatagt tttctccatt
     8281 ttctatttgt tcattcgtca atccttccaa aggattcaat acttctaaag atacacctgc
     8341 ttcgtttgct aacgttctgg caatactatc tttggcgttt tcttcaaaat aaatatagtt
     8401 gattccatgt tctttaacaa agtgtttcag ttcagcaatt ctcgccgcag acggttcttc
     8461 actagaagaa agaccagcaa tcgatacttg attcaatcca tattctaacg ctagatagtt
     8521 gaatgcagca tgttgcgtga caaaagatct ttgttttgct tgcttaaagg tttcttgata
     8581 aagctgatgg agtgcttgaa gtttctcggt ataggctgct gcattttttg tccatacttc
     8641 ctgtttttct gggtaagctt caatcagctg atcacgtatg tttgctacct gcttgattgc
     8701 taaacttgga gctagccata catgtgggtc tagctcatgt gtatggcctt cttccccgtg
     8761 ttcatggtca tgatcatgtc cttcttcact tcccggaagt aaaagcatac cttctgtcgc
     8821 ttttatcgta tggacattgc cttcttgtaa tgttttttgg attgcgggga cccatgtttc
     8881 catgttttca tcattataaa caaagatatc tgtatcttgg atctttgcca tgtctttagc
     8941 agaaggttca taatcgtggg aatcagtccc tgctggaatc aataactcta cttctccttc
     9001 atccccgacg attgcttttg taaaatcata catgggataa aaggtcgtca tcacgctcaa
     9061 tttttcttta ctgtcctcgg ctttcccact tgccccgcaa gcagttaaca tacctgctaa
     9121 aaccagcatg gccaatatac ctatcaatcg tttcatttat gacactcctc ttctcatctt
     9181 ctttcatttg aatgttccga ttcgcttttc gcaaaccgta atagttacgt tttagcaaca
     9241 ggatttaatt tatcatatgg ttaaaagaac tgtcaagcgt tttcttattt taattgatga
     9301 gaaagtttat atgaatgatt gacgatattt ttgcaatcaa cctctatcat tttcctttta
     9361 tacccgcttt tgtctataat gaagttatag ataaaggagg aaaaagagtg aaaaaagaaa
     9421 cagatacaac gaatcgtttg atccgctttt taggaggaaa aacctcttac tatgttttag
     9481 gaatagttat cttacttgcg ctgatcattt attttttcca tcagatctcg tttatattca
     9541 agcctgtcgg aatcattatc gctactatct tgcccccatt attgtttgca ctgatcttgt
     9601 attatctttt ggaaccagtc atcaaacgtt tgagcaagca cctttcgagg aacttgtcag
     9661 tcattatcgt ttatgtgatt attttatttt tattggggct tggaagcata tggcttattc
     9721 cttttcttga agaacaggca aagacattga tcagtagttt gccagatttg tttcaagatt
     9781 ttcaagagag tctccgacaa tttttggaga aaacaccttt tgccgattca tttaatcaat
     9841 ttttcgcttc tattgacgac gtgacgtctg atatagctgg atttattgga aattattggg
     9901 aaagtggcgc acaacggatc agcaacattt tttcaactgt tacagctatt tttattactt
     9961 tatttactgg tccaattgtc gcttttttcc ttttgagaga tcctcaaaaa ttttatcagt
    10021 cagttttagc gattgtccca ccagcatttc gtacagattt taaaaatttg acaaagattg
    10081 ctaatcaaca attgggttca tttctaaagg ggcaaatcat tgcttcattt atccttggag
    10141 cagtctactg ggtttgtttc ttactgatcg gattagaatt tgctagtgtt ttagctattt
    10201 ctgctgggtt gttatgtatc attccatata ttgggccgtt tatcgccttc tttccaggtt
    10261 tgatcattgc attccaagac tctactttta tggctgtcaa atttgtcatt gtctggtttg
    10321 ccgtacaact tctccacggt gacttggtga ttcctcgagt aatgggtgat cgtttacaga
    10381 tccatccgat tacgatctta atcgttttac ttgtcatggg tgatctaatg ggaattgtgg
    10441 gcgttatttt tggtattcct atctatacgt tagtcaaatt actcgttact tttattttcc
    10501 gtaaattcaa acaacgctac aataaatttt atggcgataa aggagagtat gaaaactctt
    10561 cattttctga agaagattat tttaaataaa acacaaaacg tcgatcttac gagaatagct
    10621 cgtaggaacg acgttttgtg tttttgtttt aatttttcag caaagcaatt gcctggtatg
    10681 gttttagctc cagactttga tgaagaacag tatcggaata attatcgata agaatattgg
    10741 cttctgtgaa tccttctggg atggcgatcc ttgtatcttt atcatagaaa tttgttaata
    10801 caagcagctg ctgtccttca aattggcgaa gaaagccata aacttccgga tgatttgctt
    10861 cataagcatg ataatctcct tgtgcaacga ttggatatgt ttttctcagc cgaatcaatt
    10921 tcttgtaata ggacaaaata gaatcttcag aagatagttc tttttctaca ttaatctctt
    10981 ctagcttgcc tccaactttt aaccaaggtt tccctgtagt aaatcctgct tgttctgtgt
    11041 ctgaccattg catgggtgtt cgagagttat cgcgagattt tgctttgatc cgacgaaacg
    11101 cttctttttc tgtgaatcct tgttcaagga gtaacttata agcattcaaa ctttctacgt
    11161 caatatagtc ggaaatcgat gaatagtctg ggtcgatcat gccgatttct tctcccatat
    11221 aaatataggg cgtcccacgg ttcaaatgga tcatggttgc tagcatctct gctccttgtt
    11281 ttcgatactg atcgatagct acaaatcgat tgagcgcacg tggctgatca tgattattaa
    11341 aaaatagagc attccagccg ttaccctcac tcatcttttc tccccatgta tgaaatagtc
    11401 gctttaattc tgcaaaatca aatggaggag tagaccattt attcccattt tcataatcga
    11461 ctttcaaatg atggaaatta aagaccattg ataattcttc tctactaggt tctgtataca
    11521 agatacaatt ttcgatcgtc gtagagctca tttcaccgac tgtgatgata gtggaatccg
    11581 tcccaaacgt tgcttggttc aattctttta gatacgtatg ggtgattggt ttgtccgtat
    11641 attcaggttt gccatcattt tctttattat ttttcaattg ttcgtcttta ccgataacat
    11701 tgataacatc gaaacggaat ccttttaccc ctttttccat ccaaaaacga acaactttga
    11761 atagttcctc tcttactgct tggttccgcc agttcaagtc agcttgtgtc cgatcatata
    11821 agtgcaaata atatttcccc gtatctccaa atggcgacca agcacttcca ccaaattttg
    11881 atacccaatc cgttggctct tctcttaaaa tgaagaagtc ctgataatgc tggtcccctg
    11941 ctagtgcttt tttgaaccat tcatgttctg tcgaaacgtg attcagcacc atatcgagca
    12001 tgatttctat ccggtatttc tttgcttcgg ctattagctg ttcgaattcc tccatcgtac
    12061 caaagatagg atcgatggct gtgtaatcag agatatcata accgttgtct ttttgagggc
    12121 ttggataaat agggtttagc caaatcatgt cgatgcctag atcattcaga tacgggagtt
    12181 tttctttgat tccttttaaa tctccaattc catcaccatt actgtctttg taagatttgg
    12241 gatagatttg gtaaatgact ttgtctttaa atgtcatgga tatttacctc cattcaactg
    12301 atttattacc taccacaact tatatataca agttatcatt tattattata actgaaccga
    12361 aagcgtttgt aaaatttatc tttatacatt ctaagaggtc tgttgcccaa taaaaaacaa
    12421 gagatcagac atgtatttgt ctatcctctt gtttaaaata gcaaaatatt cttgtttctt
    12481 ctataaatgg tgttcaaaag cttttatcta cggcaatcag tcttctcaaa tgtaaaacat
    12541 gaggagctaa ttttatttga gtattctttt tgctcgatgc aggacggctt ttttacaacc
    12601 tctgattcat ggtgttcaat cagctgtcct tcggtattag ctcaaaaaac ggcaaaatat
    12661 gaaaaactat tttgccgttt gtttctctaa tactcaggtc aaaccgctga tttcacaacc
    12721 tctgttttta ttcattcgat ttcaacgcat caatcatatc gatatgcttt aatttgaaat
    12781 gggtaacaat catcacaata accgtaaata cgatagttaa tcctgctgat aagacataag
    12841 cccaccatgt gatcactaat ggaaagatga cattctccat agacgcttgt tgcaagatga
    12901 agtcagtcaa tatatatcct acaccaaatc ctccgatgat tcctaaaaga gtaaagatga
    12961 tattttctcg aacaatgtac atcgtgactt ctttatcaaa aaatccaagg acttttattg
    13021 tagataattc gcgtacacgc tcggaaatat tgatattagt tagattatac aagacgataa
    13081 aagccagcag tcctgataat acgacaaaga ttaagacaac cgagtctaag ttcgccattg
    13141 attcttcttg cgtttcgatt tgtttggaca tgaaagacgt atttgtcaca gcgtctgtgg
    13201 caagcagttt ctcggaaagc atttcttctt cttttgttgt catcttatct gtacgcagca
    13261 aaaatgcatt atccatcatc gattgatcag taactgaagc ataatattca ggggacatat
    13321 aaataaagct acctagatag tttttcacga tttcttttac ttcgactttc cattcttttt
    13381 gatcttcatc ataaagcgaa atatgatctc ctgtagataa gtcaaatagt tctgctactt
    13441 tttgcgtaat agcgattcct gttttaggca aggagcgtgg gttctcttca agatcagtta
    13501 aatggataaa acgatccaaa tcagctgttt tacttggtac gatcactgtc agactttgcg
    13561 aagcatgtcc tttttttctc aattctacgg tttgagtatg aatagctagg atctcattta
    13621 ctttttcttg cttctgcagc atatccgctg ctttttgacg actatcttcc gtggatgaat
    13681 ccaatgtaac gattgcttga tagtcaatga tcgttccaaa ttgtttggct gaaacagaac
    13741 ttagagaatc tttcaatccc acgcctgcaa ccatcagccc ggcacatcca gcaattccga
    13801 taatcgccat aagcattctt gacttatatc ggaagagatt tcggtaactg attttttgat
    13861 taaagctaag gcgtgaccac agcggagtga tgtattcaag aaaaatgcgt ttccctggct
    13921 tcggtgcttt cggttgaagc aatgcagcag gccgttctct taaatctttg aataaaacga
    13981 tcattgcagc gccaaatgcg gcaatgaaga atgcggcagc tgcttgtaaa atcggcggcc
    14041 agtcataaaa aataagcgca ctcccaatat cataccgctc gttagacagc tcaaaaatga
    14101 tccttggcaa aagattcgtt cctaatatcg ttcctaaaac aatacctatc cctgaggcta
    14161 gacttgcata gattgcatat ttttttgcga tttcaacttt cgtataacct aacgccttta
    14221 atgtcccgat ttccctgcgg ttttcttcta ccatacgtgt cattgtcgta aaggtgatca
    14281 atgcggcaat aaagaaaaag aaaacaggaa aaacattggc aatcgcagcg atacgatcag
    14341 acagatcacc aaattcttga aaaccgacat tttctgaacg ttcattgtat aggtatgatg
    14401 gtttagttaa attttcaatt ttttctgcat ttcgattcaa ttcttcctct gcagaggcca
    14461 gttcacgttc tttctcaact aattgccttt cttgttcagc aagttgagct tcttgttgag
    14521 ataatgtttg aacagcgatt gttcgttgcg cttcaggaag ctgctggata gttgctgact
    14581 gttgcgctaa ctgtttttta gcatcttcta accgtgttct tgcttgcgtt gtttgtgctt
    14641 tgccatccgc tattttttgc tgtgccggtt ctaattcttc gttggccgat tttttcagct
    14701 cttctaagcg ttcttcgggt cgatcttgta aatacttttc tgccttttct tgattttgct
    14761 ccattttatc tttgtaagct ttgctgtacg tattcaaatt ctttacgttt gtaaaatcaa
    14821 gatataagac agaataaata tctgttttaa aaacggattc aggtaaatag acaaaataat
    14881 cgacgctacc atttccgacg ttcgcgtatc ctctctccaa attgttgatg aacaatggag
    14941 aacggacaaa gcccgtgatg gtatactctt tttctttcaa ttcatctgaa tcaatctgat
    15001 aaatatcacc gattttatac ccttcatctt ccgctttttc atccaataca agctggtttg
    15061 gtttttccgg gagttttcca tcagttaatt gtagcttgtt ctgcttgtta tttttgttat
    15121 aagaaaatat ttgaatcact tcgtttttgc cagtattgga ataatagatc tgttttcctg
    15181 tttctacttt tgcatctggg atcttttctg cttgagcaat atctttttgt gtcaagccac
    15241 cagtagaaac gatttgcaaa tcagaaagtc ctgctgtacc aacatagtga tccatcgttt
    15301 tttgcatgac aggtccagca gttttgacac ctacaaataa aagtgttcct agcatgacaa
    15361 taaggatgat tgcaatgaat cgtcctttag attgccgaat ttcgcgaaaa cctgctttaa
    15421 gatatgttct tgttttcata aaatccccct accatacaat ctcatcaatg gatgaaggat
    15481 gatcatttaa ttcaacagac cttactttag catcattaat gtgaatgact ctatcagcga
    15541 tgggcgctaa agcagaatta tgtgtaatga tcaaaacggt attgccgtgt tgtctgctag
    15601 cgttttgcaa taatttcaat acttgcttgc ccgtttcaaa atccagcgcg cctgtcggtt
    15661 catcacataa aagaagtttg ggatttttag ctagtgcacg agcaattgaa accctctgct
    15721 gttcgcctcc tgataattgg gacggaaagt tattcaatcg atgagctagg cccacttgcc
    15781 tcaatacctc tacaggatca agcgcatcag gagaaacttc cgttgccaat tccacatttt
    15841 cttttgctgt tagattagga acgagattgt agaattggaa aacgaaccct acatctgttc
    15901 gtcggtaagc agtaagctgt ttatctgaaa attgcgcaat atctgtgtca tcaataatga
    15961 tctgaccttc atcaggtgta tccatcccac ctaaaatatt aagaatcgtt gactttcctg
    16021 ctccacttgg accaagtata atcactaatt cgcctttttc aattgaaaaa gaaatatcgt
    16081 catttgctgt aatggtcgtt tctcccattt tgtatcgttt gtattcattt tttacttcga
    16141 catacttcac tctgattcct ccattttcac gatatttctc gctatatcta tgcatcgaat
    16201 gcgttttctc acacttattt attttaccac tgaatttctc tagactaaag aaaggaatcc
    16261 tttaatttag ttgacaaata aacgatttat gatttactta cataaaaaac attgttattt
    16321 gaaagaagga acatcatgaa tgatttaaag gaaaatatga tttttgattt atcaaaaact
    16381 gcttttgtcg cgatcgacat gcaaaaagag atcgtaaata acggtacact ctctccacac
    16441 actgcagcat ctattctgac aaacaatgat ttgttagtaa gaacattgaa acgtaccgct
    16501 gccttgaaag ttttagtgaa cgtagacatc tccactttcc cttatttgag tcaacaaact
    16561 gatatgggtg gaatgactgc ttctgtacct ccagaattca ctgatttact tttgaaggat
    16621 tctttgaaag atacagataa tatgttgact atcacaaaat acaatccaag tgcttttttt
    16681 ggtacttctc ttgatcttca acttcgccgg cgtggaatcg aaactatcat tttaagcggt
    16741 gtagcgacaa caaacggtgt atatgctact gcattagatg cctttcaaca cgggtaccat
    16801 atcgtgcttg ctgaagatgc ttgcagtgat cgtgacaaag aatcccatca attgttcata
    16861 aaaaagatat ttccgaaaac tgcacgagta cgctcaacga aacaaataat cgaagctatc
    16921 caacaaagca aataagtact ggcacacgtg attttcattt acttcttttt gatttcatgg
    16981 gaaaataacc acaggattta gataggagta tgaacatggt gaaaaaaaag atcacaatca
    17041 aagaagtcgc taaactttcc ggcgtttcaa tcacaactgt ctccttgata ttaaatggaa
    17101 atacggagaa attcagtccg aaaactgttc agaaagtttt agctgccaaa gaagaattag
    17161 gctatcagcc tgactatttt gctagacaaa tgattaccaa ggaaacgaaa acaattggtg
    17221 tactcgttcc tgatatcacg aatccattct tcagtacact gatgcgagga attgaggata
    17281 tcttgtataa gcagaatttc gtcacgatat tatgtaatgc tgattctgat catcaaaaag
    17341 aaatcgaata tctagccgag ctcacacgtc gaggtgtgga tggattcatt atcgcgactt
    17401 ctgctgtctc tacagatgca atcaacgaaa atttgaaaaa acaaggccgg cccttcattg
    17461 ttttggatca gaaaaaatct gaaggattta gtgatgccgt acgaacagac gattttcgcg
    17521 gtggttacct agcgggcatg cacttgctta gtctaggaca tcaaacgatc gcccttgtct
    17581 atcctgaaaa tccaccggaa aatgtccacg ctcggattga ggggtttaaa tctgctcttg
    17641 atgtttacca aatccctcac gaccaactga tcctcttacc tacacagttc tcaaaacaag
    17701 gtggctacca gatcacagca gaacttcttg attctgctgc aactggtgtg tttgctttaa
    17761 atgatgaatt agcttttgga ttatatcgcg gattagagga agctggaaaa agcatccctg
    17821 aagactacag cattattggc tatgataata tagatatgtg cgagtatatc aagccgaaac
    17881 tgacaacgat cgcacaacca atcttcgaat tgggacaaac atctgccaag ttattgttag
    17941 atcggatcca attcccagaa aaagaatggg aagaaaaaag attacctgta cgattagaaa
    18001 aaagattttc aactgcaccc ttgaaatagc tttcaaggtg tgctatattt ttatcgaact
    18061 attaaaacgt tttactaaaa cgttttaaaa aataattttc ccatcaaaat aaatgagata
    18121 gttggaggtt tgtaaaatga acacggttac agtaattgga agtattaata tggacactac
    18181 ccttcgttta accaacatgc ccaagccagg cgaaacgatg catgcgcatg agatttttca
    18241 cgctggcgga ggtaaaggtg ccaaccaagc agtggcagcc aaacgttcag gcgcacggac
    18301 atcttttatt ggaggcgttg gggctgacag cgaaggacaa cagttattag atctactgac
    18361 aaaagaaaac atcgatacat ctgggatagc tgaaatccaa ggcgccacaa ccggacaagc
    18421 aatgattatg gtagacgcag caggagaaaa tagtatcttg atccatgcag gggcaaataa
    18481 tgctttccat gaacaagaag tcctaaaaaa caagcaactg attacaaaca gtgactttat
    18541 tattgctcag tttgaaagta gcttagatgc gacgatccta gctttttcta ttgcaaaaga
    18601 cgcaggaaaa acaacgatct tgaatcctgc accagctcgt gaaacgattc ctactgaact
    18661 acttgaaaag acagatatca ttataccaaa tgaaacagaa acagaaatca ttacaggaat
    18721 cagagtgaca gatcataaca gtttggtcgc agcagccgaa aaactccatg aattaggtat
    18781 tggaacagta atcattacac taggcagtgc cggcgctttc tatcatacag aaaaagaaca
    18841 cggtatcgtc cctgctttta aagtggatgc cgttgacaca acagccgcag gtgatacatt
    18901 tattggcgca ttaagcagca cacttcagcc agaccttagt aacttgaaag aagcgatcct
    18961 ttatggaaat ctagcctctt ctgttgctgt gcagtcttat ggtgcgcaac cttctatccc
    19021 ttaccgcgaa gctttagaac aatcagcagt ctaaaattaa caatgagagg aagaaacaaa
    19081 catgaaaaaa ggaaaagtaa tcaattcaga tatttcacga gtaatcgcac aaatggggca
    19141 ctttgataaa ttaagtatcg gggatgcagg catgcctgtc ccctttggta ctgaaaaaat
    19201 agatttggct gtctcaaacg gtcttccaag ttttttatct gttttagaaa acgttttaga
    19261 agaacttgag gtacaatcga ttgaattggc ggaagaaata aagacaatga acccggaaat
    19321 attggaaaaa atcaaattat tgttaccaga tacaccgatt agctttatcc cacatgaaga
    19381 aatgaaaaaa gagttgaata actgtcatgc atttattcgt acaggcgaaa tgacacctta
    19441 cgccaatatt atattagtga gtggagtggt cttctaatgg aaacgacaat gaatcctgaa
    19501 cagatggtac tgtccgagca gattcatatg ctgattgaac agttgggagg aaaagacaat
    19561 attgattctg tccttccatg tgcgactcgg cttcgtatca aattgaaaaa acagccagta
    19621 gccaatgcag aaaaattaaa acagcaaatc ccttccatta agtatttcat tttactcgat
    19681 agatatgcag aaataatcat ggatcaggga ttggctcctg cttacaagga attgacgcgt
    19741 caaatcgatc attcagctcc gaaagaaaag ctaaatccga tcgaaaaact atttggtttg
    19801 atatcggaaa tctttacgcc gatcattccg ctgtttgccg gttctggtat attaaaaggt
    19861 ctggttgttt tagcgactac gattggctgg cttagtgaaa caagcggaac ttatcatatt
    19921 ttgtctgctg cgtcgaatgc cgtcttttat tttctgccaa tctttcttgc tttttctgct
    19981 gccaaaacgt ttaaagtgaa tggatatatt gcggctgtca ttgctgcagc actgattgaa
    20041 ccgaatctga cctctttact ttcagacagt ggcaaagcag ctactgattt tctggggatt
    20101 cctgtagtac tgatgcagta tacgtctact gtcatgccgg cgattttagg tattttcttt
    20161 tattcttttg ttgaaaaatt cctcaaaaaa tatattcgcg aaaatatgca attagtattt
    20221 gtacctttac tttcattagt tatcacggtt cctttgacgt taatggtatt cgggcctgcg
    20281 ggtgtttacc ttggcgaagg tttagctgcc gcaattactt ggatgatgga tattaacgga
    20341 ccgatcagtg gcgcaatcat cgctggtggt tggaatattt tggtaatatt tggtatccaa
    20401 tgggctgtaa accctgtcat gatcagtaat atctctgctt atgggttcga ccgaatcgtt
    20461 ccgttgacag gagcagccaa ttttggaatg gctggtgcag ctttaggtgt atttctgcga
    20521 agtaaacgtt caaaaacccg ttcgatctcc ggttctgctt ttgcttcgat tttacttgcg
    20581 ggagtgaccg aaccaactgt ttacggaatt gcgatcccat tgaaaaaacc atttgttgct
    20641 gcttgcattg gtgcagctgc tggtggagct gtaatgggat ttgcccaagt gaaagcgatc
    20701 gcttttgtat ttggtagtct gaccacattg cctgcattca tttccggtac ttttttctgg
    20761 tacttagcag gactggctgt tagtctagtc gtagcaatga tcactactct cgttagcggg
    20821 tttgatgaag acctaatgtc ttatgaatag ttaatgaaaa agactgaagt atgagatgtt
    20881 tatcacatat ttcagtcttt ttctttttag gatcattatt tttataaatt tttgtgatac
    20941 tttccaaact ttggtataat ttacatatgc ataaccattt ttatccccac ttgtttatcc
    21001 ccaaacaaag gtggtctatg caataaaatg aacgtcaaag aaaaacgaat gaatgctcgt
    21061 tgcttattta caaattgttt tatttagaat acacagacag atttatgaaa agaaaaagct
    21121 tttcgacacg attatctgtt ccaaaaaatg tctaatgaat gctgaataag acagaaaatc
    21181 aatgaaagga aaaggactag tttattatga aaaataaaaa aacgatacgt ttgctagctg
    21241 ctacttggct gattgctccg tctgttttgt cgaccaatac cgtatttgcc gtagataatc
    21301 aaatagctga tcaaacagtc acaacagata cgactacatc cagctcagct actagtgaaa
    21361 caacggattc ttttacagaa gacccaactg gaacaactaa ctcaacaaca ggatcgaccg
    21421 agccaactga aattgatccg gctgatccat cagaaaatga aaagccagcc gagacatatt
    21481 cccttacaat tgctccttct ttgattggta agatccaact gactgcttcg acagcggatt
    21541 cccctgaaca gcaacctttg gatattacgg aaagtggaac ggtagaaggt ttattagcgg
    21601 aaacgaaggt aacttacact attacgccag ctgaaggtga acaaattgct tcagtcgctg
    21661 ttaatggtgc caaagaagta aattatgatg caaagacctt tacagtaggt acgaacaatt
    21721 tatctattac tgcagaattt aaagctggac cggatacttc aacagagaaa ccaactgatc
    21781 ctagtgaaga agtccctagt acaccagatc cggaaacgcc aaacaaacca gatgtgggta
    21841 ataacaacaa taataatggt tcaaataatt caaacaataa taacaataat tcgaacagcg
    21901 ggaattcttc gaatcaaaca aacccatctg gatcgaataa caatggaaat actcagagag
    21961 aaccaaacca tccaaacaat ggttcatcga atggcggaac gaacaatgct tcatctcgtc
    22021 caaatacagc aaatcaaagc ggtatagaga atccatcttc tgcttcttct gattttgttg
    22081 taaaatcacc aattgatgct gtattgccta caaatacaac gaatgtccaa caagcaatcg
    22141 ttcgagaagc attcaagcat cttggaaaac catatgtatg gggagcaaaa ggtccaaata
    22201 cttttgactg ttctggtttg acttattacg tatatatgaa agcaaccggt cattatatcg
    22261 gtggctggac aggcgaacag caatatgcag gtacgcagat tccagtaagt caggcccaac
    22321 ctggcgacct cgtcttctgg ggaccttctt ccggtgttac tcaccatgta ggtatctata
    22381 ttgggaacgg acaatttatc catgcgcctc aaccaggaga taaagttcga gtaacttcta
    22441 tttcagattt cacgcctgat tttgctgtcc gagtaaactt agcaggttta cctgctgctt
    22501 caggttcgct gacaggcggc tcatctattt tagatggatt agatggctcg ttccatttca
    22561 gtcaaaacca aacaactgat cagttcttga aaaagattgc agatgatgca caggaaatcg
    22621 ggcaaaaaga aggaatctac gcatcagtca tgatggctca agctatcctt gaaagtggat
    22681 ctggaaacag cttattatca agcgaaccaa atcataacct ttttggtatc aaaggatcat
    22741 ataaaggaag cagcgtgacc ttcaatacac ttgaacaaga tagttccgga caaagctacc
    22801 aaatccgcgc acaattccgt aaatatcctt cttacaagga aagtttggaa gactatgccg
    22861 acttgatcaa aaatggactg actggcaatc ctgatttcta caaaccaact tggaagtcgg
    22921 aaacaaaaga ctacaaagaa gcaaccaaat atttggaagg acgttatgct acagatcgcc
    22981 aatattcaca aaaattgaac gcgatcatcg aagcgtacga cctgacaaaa tatgatgaac
    23041 cgaaaaaaga agcagcaaca actgaagaag caaacgctga aatcctcaat atgtctaagc
    23101 gattcgatgt gccaatcaaa tggacaacag atggcgtgcc aatcacagga ttagaatttt
    23161 caacgataaa acgcgtcaac aacgcttctt ccatcttccg tgtcgcttca atctgggatt
    23221 tgtggaacaa ttttacggca agacagatac cagaaacaac tactcgtaca gttaaagctg
    23281 caactgttcc tgtactaacc ttgttaagtt tagacaaatc attctggctt gatctgcctt
    23341 taaagaaata gaataaatta aaaaggggat gtgacactgt cacactccct ttttaattta
    23401 ttctatttct ttatatttat tttgtattcc gttacaaact cgcgtacttg gttaggttcc
    23461 agagtgacat ctccaaaact ttcaagtcgc tccgctcctg gcagttcttg agtctcaaat
    23521 gtgataccgc catgatttac taatttattc ccgcgcattt ccggtccatc ttctccaaaa
    23581 tttgctgtaa aaatcacgat tcctgaagca tctgttttta cttggatcga tactttttca
    23641 tctgggcttg tcaattccgc agcatttagt aaaccagatt gttttttcaa caaaaatgga
    23701 tgatcgatgc cgcccactat cattgattgg cgaaaatcac tggcaaagac ctcacctaat
    23761 tttttaggac gttggaagtc aaatgctgtg ccacttactg aaactacttc tcctgtaggc
    23821 gttgtatctt tattgagcgt agcaaataat cggctattca accaaagtat atgttcgtcg
    23881 attgactgtg ctggatcacc ggttaaattg aaatagacat gatttgtagg attgaatact
    23941 gttttgcggt cactgatccc ttggaccgtc actcgccatg tatcatcgtt cgtcagcgta
    24001 taccgtactt ctacatctaa agttccagga aatccgtttt ccatatctgg gctagtctga
    24061 tagaaaatga ccgatgcttc gttttcacca ttgatgactg tataatgcca ctgcttggct
    24121 tcaaagctag gtgcaccacc atgtaaacaa tgaccagtgt ccgggtctgt ttttacttcg
    24181 aacgtttcat catctaattt gaatgtgcca ttcgtaatcc gtccagccat acgtccgatt
    24241 gaagcaccga tataagggtc tttttctaga tattcttttg cttcatcaaa acctaagatc
    24301 aactctcgtt tttcattatc gattattgtt tgaaaatgaa caacccgtgc cccaagatca
    24361 ctgacagaca aagatgtccc attttgattc gtgatcgtaa tcaagtgata gttttcgcca
    24421 aaattttgtt cattgatttc catgttcctt gcaccctctt ttctttcatt tgcactgatt
    24481 ccagcataca tggaaaccgt tttcttaaca gcttattccg tgagtaacga gaaaaaattt
    24541 actatattct aataaaagac cgtgaaaaaa aggttgtgac aaaaatattg tcacaacctc
    24601 tttttccgaa caaacggtgt tcaaaagctt gcatctgcgg taataagccc aaccaaacga
    24661 aaaatatgag gagctatttt tgcttggctg ttcttattac ttgatgcagg acagcttttt
    24721 cacaatctct ttttcaatac gattccagta tataaccatg tcgtcagtac atagtagatg
    24781 aaatacaata cgaagaatat cgtaaacgga acccaaatat ctttgtatgg attttgcatg
    24841 aatagaccaa acatttgtaa tccgaataag acatggacta cacctaagat tcctggtgct
    24901 aagaataaca cgcctacttc tctacggatc gattgtttaa gcaacccgcg tcgtgttcct
    24961 atcttttcaa gcatttcata acgagcaatg tcactcttgc ttcctgacaa gatcttgaac
    25021 atcaaacagc tagcaagcat ggtcaagaaa gctaaaccta ggaagaatcc cataaattca
    25081 aaaccagaga atagaccatt atacacttca tacatttcat atttctggtt gctgtactct
    25141 actttttgca aagatggatt gttcatttta ttttgagcaa caagtgtttc gattggtttc
    25201 aggtttgctt ggaagtcttt tacctgaact agctgtaaag tggattgtgg caagttcagt
    25261 tgatcaaatt ctgattgact gactaccttg atttcttttt cttgctgttc cggcaattca
    25321 tagcttcgaa gttcctcttg tacagtcagt tcattcattt ttttagcagg aactttttct
    25381 ttcgtgatct tcggcggtgt tccatcttca tgttttatca tgatcaatgg ttgagccgca
    25441 aattcacttg cattatagta aatcgttccc gcatcttctt tttgagtata agaagcagaa
    25501 agtgttggtg aaagttcttt gattttttgc tgatcttctg cccgaggatt attcatcact
    25561 agatcatatc cagaattgtt ttctgtcaag tctgcaattt catttttaaa acctaatcct
    25621 accgtcaaag cgcccagtgc caaggcaaac agcatagcga ccattgagag catttgtgta
    25681 tattcacgaa tacgaaagtt taactgtgac aatgtgaaat tgttcaattt tttcaatgaa
    25741 atctgttctg atttctttag taatgataaa aagaaaatga tcacagaatg gaaaatgaaa
    25801 taagttccta atacgatcgt aactaaggct acccctatac caaagacttg ataggtcccc
    25861 acgtgtttca tcatatagta accgcagcct agaaaagcaa ttcccagtac tacttcaagg
    25921 aaaaacaaga atttatgctg cttgattctt gttggtgtct gatccgcacg aatcaatgct
    25981 aaaatcggtt ttttgacaat cgaaaaagca ttgacaacag cagctaataa aaacaaaaca
    26041 gcaaaaaaca aaacagtgat caacaacccg tgaatactaa aaggtgtaaa atgcgaaata
    26101 ttgagatcta actgatccac taataatcgg tggacgatac ttgtcaatcc tacaccgaca
    26161 gctgaaccca ctaaagtagc tgcgatccct actaagaatg tttcagaaaa aatcatctgt
    26221 gcgatttttc tgccttttgc tcccagcatc ataaacattg catagtcttt ttgccgcatc
    26281 gtcatcaaaa aggaatttgc atataaaata taaacgaatg tgatgatccc tagtaaaaca
    26341 gaaccgaatc ggaaaatgat aactgtagcc gcaacgatcg tattactttt caaaaaagct
    26401 tcgttgcttg ccattgattc aaacatgtaa aaaatagcag atgccataac taatcctgag
    26461 aataacacca agtagtctct taaacggctc ttgatcccag taagtgataa tttccaaagc
    26521 atagtcaatc tccccctact gttccaagtt tccaagaata gatagtattt ctcgatagaa
    26581 ggaatcacgg ctttgatctc cacgtttcac ttcttgatgg ataccgccat ccttgatgaa
    26641 taaaatacgt tggcaataac ttgcagaaaa cggatcatgc gtcacaagaa gaatcgatac
    26701 atgatctttt gtattcaatt cgtccatcgt atctaaaaga tcccgggcac ttttggaatc
    26761 cagcgcacct gtaggctcat cccctaatag aatcgttggt tgtgtgatca atgcacgtgc
    26821 ggcggcgacc cgttgttttt gtccaccgga aatctcagaa ggatagcttt ccaaaatatg
    26881 agagatggat aaacgttctg caattttttg gacacgttgc ttgatttctt ttggtctgac
    26941 gccttgtaaa gaaagaggaa cagcgatatt ttcttgtgct gtcaagcttt ctaataaatt
    27001 gaaatcttgg aaaataaagc caatctcatt cgcacgaaaa tctgctagtt gatttccttt
    27061 taatgtggtc acatcttttt gattgattcg gatatgccca tctgttggtt tatctaatgt
    27121 ggataaaata ttcaaaagtg tcgacttacc agaaccagaa gcgcccatga tcccaataaa
    27181 ttcgcctttt tctacatcga agctgatgcc gcttaatgct tgcgtctttt tctcattgtt
    27241 ttttccgtat acttttgtta cattctgtac ttcgactatt ttgttcattt ctttccctac
    27301 cctttaatta gtttttccag tgctgttttc ggcacgtctt ttttttcgac ttcttcatac
    27361 gaagtgacac ctttattttt gttccaggtg atttttaaat atgctccttt acgaagcggt
    27421 cgagtcaatt gtcccttgaa gtccagttct ttttccttac cctctttcgt atagccaggc
    27481 aggatatatc tatagttgac tgtttcttgt ccagagtctg attttgaaac tgtttttgta
    27541 ccatctgtcg taatttgtac atagtattct tctccaccca taactacgta atctgcgatt
    27601 ttcacccctg caagtaccac aacgatgaaa acaagtagac cgatcagaag ttttttcact
    27661 ttttcccctt ctctcttact ttatatactg attatagaaa aaagcgaaca attctgcctt
    27721 cgaatcaact atcattcttc tttcaatttt gtcattttct ttaaaacaac taaaaaaaga
    27781 gttcaagaca ataatccgtc ctaaactcct tcttcctatc ttacaaaaag tatgtcactt
    27841 acggtctttc atgtcgcctg tattgataac aggttgcgtt cctttgtctg taatgattga
    27901 gacaagtaaa ttattgatca attggacttt ccgatcatcg gtgaaattga tttcttgtcc
    27961 atcttcgatt tgctctaagg ccatttgagt gattgtgaca gctccttcaa caatggtttg
    28021 tcgagcagac aaaatggctt ttgcttgttg acgttggagc atggcactag cgatttctgt
    28081 tgcataggct aaatggttca agcgtgtttc gattacttcg acacctgcta ctgctaaacg
    28141 ctcttgcagc tctttttgca actcgtcaga cactgccgtc gtgtttcctc gaagcgtcaa
    28201 atcattctca ttgaatgtat catacgggta ttggctagcg atatgccgaa tggctgtctc
    28261 actttggatt tctacaaaat cttgataata cgctacatcg aataatgcct ttgctgtatc
    28321 aacgacttta aagactacta ctgctgagat ttcgatgggg tttccatcca aatcattgac
    28381 ttttaaaaca gaactattga aattccgaac tttcaacgaa acagtcattt tttgtgccaa
    28441 aggtatcgta aggaaaaagc cattttctcg aatcgtacct aaatattgtc caaaaaacaa
    28501 aattactttt gcttgattag gactgactac agttgccgaa cttaacaaca ataacgtgat
    28561 caaccaaaga aaaatactta aaaaaagtgc ccaaactttc gcttgccaca tacctaaata
    28621 gaagaaaaac aatccaacta aagctaatac gaccaatccg acaatccctg cataaccatt
    28681 gatataaaat gctctttttt ctctcatgct acttcctgcg ctcctttatc cttcaataaa
    28741 tatctaatgt tactttttta attttttttt cgaatacgcg ccattacacc ttctagttct
    28801 aactctttgt cttcagtgat gtaccaaccg cttgcctgtg tccctccggc tgcctgcggt
    28861 aaataatcca attttgttcg aacccagtgc ttttcttctg taaaatagtc ttctaccaag
    28921 acctctagat ccatccctgc tgaaagaggc aaatcttccc gaacagattt aaagataaat
    28981 cgttccttct tcccatcata cttcaatatt cctgtatcga taatcggtaa agaataataa
    29041 tccagctctt tcttcaccgt caataaatgt ttgaaaactt catggtacac ttgctctaat
    29101 tggcgacctt ctgaattgtt cgggtaatta accatcactt tttctttgtc tggatcatag
    29161 aaggtttggc ttagttgagt gatataagta tgtaatcttt ccatttctgt ttttaacttt
    29221 tctctttgac cttcttctac cttcatatac tctttcaccc tgttttcttt ttagatattt
    29281 tctttcttat tttactatag ttatgtgcgt taagcgatga aaaacagcaa agattggaag
    29341 gatctttgct gttttttctt aaaatatcca gttgagtaca ggatcaatct gtttcattgt
    29401 cctcttgatc cgtcgtaata ttgatcgatg tgtctttagc agtgatcttt agctttttct
    29461 gtccttgttc taacaaagta tttgttattg gctggtagtc tttttcaata taagattcac
    29521 cagacgtttg gatagtatag ccactgtttt ccatctcatg caaagataaa ttgccaccgt
    29581 ttaggatgac ttttccttct ttgctgatca aactgtcttc tagatggaag ttgctgtttt
    29641 cacctgtgac gatcaagtta tccacattgg cctcatctaa tcgaagtgag cctaattcat
    29701 ctttcgcagt tattgttcct cctgtaaatt cattgaacga tacccagcca tcatgtgtct
    29761 tagtattcac ttttttgatt gatacttcgt tgatatcaat tgcactatta ttcccttcga
    29821 ttgtcaattc agataattca tgatctgcag ggacaacaat agtgatttgt gcacttgtgt
    29881 cttctaaact aatgattgca cctgttgatt ttttgactgc attcacagtc aacacgccat
    29941 ttttctcctt tatttctggc ttttctgtct tatcataagt cgtttttatc tcaaaatcca
    30001 atccgcgtat gaccgaaact gtttgatttt ctgcatggat gacgattttg tttgcatcct
    30061 tgattttttt tgtctcagta accatatcga tcaaccgagg accattatcc caagtcagac
    30121 tcttttgagc gcctaatgta taagttgcac ctgctaggag gccaccagta agcatcagac
    30181 caataccggt aatcaaaaaa tgtttcaatc tcaatttatg tgtcctcctt caaacgcccg
    30241 ctgaatgcag atctcttttt gtaataaaac gtcgtcccat ccatttaaca aagttcatca
    30301 tgacataaaa aagccctttt gttcctttca gcaacagtgg cgaaataaat actgcgcttc
    30361 ctgtggcgaa cagaccgaca ccgataaaga ataatccact cagaatcgat tgtccaaaca
    30421 cactgattcc tgagatgatc atgaataggc caacacctaa gatactgata cataaaacat
    30481 agatactaaa aatgagcgct agtaaagcaa ccaatagtcc cccaataacc aatataaacc
    30541 ccagtgctag tggaatgagg acaggagaag caaataaacc gataatgatt aaccaaatca
    30601 ggcgaatttg tctttttgga tttttcacta actcgttttc tgcttgttct tcttctgaaa
    30661 agtaactgat ttttaatttt aaggcaaact gctttggtgt accatattca tcaatgatct
    30721 gatctaatgt ttttccagaa tctaaaaaat attcctcata atactggatc aaatcaaaac
    30781 gatcgtcttc aggaatttct tgaagatgat ccacaacttc attcaaatat tcattcattt
    30841 gtgctctcct ccaataaccg gtctaaagaa tctcgaaaaa caatccattc atcaataatt
    30901 tcttctaaat gacgacttcc cattggtgtc aacgagtaat atcgacggtt tctgccttca
    30961 aaaggttcat cataggtctc aagatatcct tcttttttca atcttctcaa aaccggatat
    31021 agtgtagatt cactgacaga gagactttct tgtacgattt ttgttaaggc atacccatac
    31081 atatcttcct tgcttaatgc tgctagcaca gtaccatcaa gaagaacagt tggaatctgg
    31141 atgtgcatta cgtcaccttc tattctcaag tgtaatattt tatttcaatc tatattatac
    31201 aacatataat atagtttcaa aatcagtttg tcaaatacaa aaaaactgac taaaagattt
    31261 gatccttttt agtcagcaaa aaatggcttc tctttgattt ttattataac agtggcataa
    31321 tccaatttgt ccacatccag ctcagtggca tgataacgat cattgcaggt atcatgtcag
    31381 ctactgggaa cattttcacg ttgatcattc taaaaccggt agcgaccatc aagaatccgc
    31441 cgcaagcttt aaaatctaag atcatgtctg gtgtagtcaa tggataaata aattttgcca
    31501 ataagaacaa aatataaaaa ataatgaatt ggggaattgc tatcacagaa acgacatacc
    31561 ctaaattaca cgcaaaaata gctgctgtga aaaaatcaag gacagattta gaaatcaaaa
    31621 tcgtactgtc tcctgtcatc ccagaatcta aacttccata gatccccgta ccacttgcac
    31681 aaaatagaac aatgaccgtc actaatgtgc tgataaattc atcgtgggtc ataccaagct
    31741 tttcactagg gaagatttta gaaataggta cttgcatcag cgcagcccct ttatttatcc
    31801 cattacctaa atgaacaatc aaaccaatcg ctgttcctat cactaaagca aaaataacag
    31861 ccggcatatt tttcatcggc gcaatggaat agattcccat ccccatcgaa cacacaccaa
    31921 aaaccatcgt cagctgtgct ttaaaatgtt cacttaattt atttcctact aatccgccaa
    31981 ttagtccgcc aaacaaaacg gaacctacat tgatcaaaac tccagttggc atcaaaaaac
    32041 tcctctcttt ttctacgaag cgaaaaaaat cagaaaaatt tctgtaatta ttgctttcgc
    32101 tgcaagaaag attgtaacag acagagaaga ttacaccaat tcattttttg tgttaaagta
    32161 ttctttattg gaataagtag gaggaatatg atggatatcc ataaattcga agtttttctt
    32221 gatttagccg aaacaatgaa tttcaccaaa actgctgatc gacaattcac cacccaagga
    32281 aatatttcta aacagattct ttcgttagaa acagaattag acgtcaaatt attcgaacgc
    32341 gcccatagaa aaatcgaatt gaccgaagct ggaagcttat tgctcccata tgtaaaaaat
    32401 gtcgtagaac aataccatgc tatgcaagaa gtgcttgaaa cctatacgaa agacaacaat
    32461 ctttcattaa atatcttaac gataccgaca atgatcaatt ataaaggttt ttccaaaatc
    32521 accgagtttt tgaaacgcca tcctgaattt acagtccagt tgaaagaagt ggaaagtgtc
    32581 gaattaactt acaatgacgc caatgaacat agtgacacga tccactttgc tagaagtttc
    32641 caggccccac caagttcgat tgagtggttg cctactgaaa cagacgattt tgtagcagtt
    32701 ctacctaaaa atcatccttt agctagtaaa aagaaattgg atctaagcga actgaaaaag
    32761 gagaactttt tgctccttgg ccccactacg aacttgtatc aacctgtact agatctgtgt
    32821 cgcgaagctg gatttgaacc aaaaatctct tataaaggag caagaatcga cttgatcatc
    32881 aatatgattg caaatgacat ggggattgct attgttatgg aaaaaacagt caagaatcta
    32941 ttaaaagaaa atactgtgat tctccctatt tctccaacaa cagagagtta tcttgcattt
    33001 actcgtaaag tcggtgagca ttctttggct tcagatacat tttgggagta tttaaatcaa
    33061 gaagaaaact aagccctaca ttttctgtcc atctatccac ccaaaaaaag agagcgacgc
    33121 atgactttcg ctctctttct tgcatcatgt ccttgtttca atgacacctc taacatttct
    33181 cgtagttcaa taagaaagca gcgattttta tgccaaaaga accgtaagaa catttcccta
    33241 atcacaaaaa aacgactaaa aacccctaaa aaccttcaat agaattttta ggggttttat
    33301 tctttttcct attgtttact taaccgtatc attgctgtcg ttcctactcc ttcgatactg
    33361 ctataatcaa tacgtccatc atgcagttct agaatttttt taaccagtga aagtcctagc
    33421 ccattcccag aaatttgacg acttgtatct ccttgataaa atttttcaaa cattcgatct
    33481 ctggtctctt cattcattcc tacacctgaa tcggtcactt ccagtacaat ctctgtggct
    33541 gtctcaaata gtttgatatg aatctgtcca ttgatttgat tgtactttat ggcgttatcc
    33601 atgatattca gccacacttg gtacaaaaac tcttcattgc ctgtgtaatt tactgcagca
    33661 agttcgatat ccaattctag ctgttctttc tcccatttag gctgaaaaaa aacgattact
    33721 tctctgattt gttcatctaa tcgatactct ttcttttcca gttggatacg ctggttttcc
    33781 agtttgttca attttaagat gttctctgtt aattgtgaaa gctgcgtgat actttcgata
    33841 atccgatata aaaatatttg gcgttcttcg tcagagagat ttggggcttg taacaattga
    33901 acatatcctt ggattgttgc tagtggtgtt ttgaattcat gggatacact ggacacaaag
    33961 tcattcctca gtgtctcgat actattgagt tcttggacca taacgttgaa atctttatac
    34021 agttgctgta cttctgctac tttctgctgt tcatccattc gaatcgaaaa atctcccgtt
    34081 gctaccagac tcatatttgt ccctagcgca ctgattggat gcaggatacg ccgcccaaca
    34141 aaaatcgata ttcctgtacc cacgaccata ctgaaccccg caaagacgaa taacgggtat
    34201 aacgttggtt ttccagccga ttcagcaggc gagatagaat gtcgagacaa taagaaaata
    34261 aaaccgagaa aacacagcag tgtcactaag atcgaaatga agacaatact agcaaaatag
    34321 atccataatt gtgaaaatag cttttttttc atctttaaat aaccgcctta tagcctagtc
    34381 cccgtactgt gatgatttga aaatcttccg tcttttcaaa acgggtcctt aaacgtttga
    34441 tatgtacatc gatcgttcgt tcttctgtat tcgtatctaa tccccaaata tcatccatca
    34501 actgttggcg agtgaagatc ttgttgggat aagacagtaa tttatacaga agcagaaatt
    34561 ctttttgagg cagaatcaac gaatgctgat cttgtaacac tgtataagca tctagctcta
    34621 attttgtttg tccgattatc aagctactgc tgtaattgat ctttgaacgt cgaagcaatg
    34681 cttccacacg taggatcatc tcattgacat cgatgggttt tgtcatataa tcatctgctc
    34741 ctaatttgaa cccgcgtttc ttatcctcaa aatcggcctt tgccgtaatc attagaacag
    34801 gtgtgtcaaa tctggtgcta cgtaatgagt ctagcaagtc atagccatcc attttcggca
    34861 tcatgatatc tgtaatgatt aattctatac gtgtcgcttc tagttttttc agcgcatcct
    34921 ctccattcaa tgcggtgatg actgaaaagc ccgctcgttc caacacagaa cggtaaagca
    34981 actgtaattg cggatcatct tctactacta aaatacgatt cattgatctc cctctgtttt
    35041 ttgaaaaatt tctagatttt ttcttgtagt tcatcttcag ttaacattta tttcgtatac
    35101 tacgatcatt gttctgatat acttattagt ataccgaata tttcaatacg ggagaagggt
    35161 gattatgctt caattaaaag atataaaaaa atattataaa gtcggcgaaa ccaccaccaa
    35221 agcattggat ggtgtgtctg tcgctttcag acaaaaagaa ttcgtagcga ttttaggtcc
    35281 tagtggttct ggtaaaacga ctatgctgaa tgtgattggt ggactagata attatgattc
    35341 cggtgatatg gtaatcaacg gaaagtctac taaagacttt aaggacagtg actgggatgc
    35401 ctaccgaaac aactctatcg gtttcatttt tcaaagttac aacttgattg gtcatctagg
    35461 cattattgaa aacgttgaac ttgggatgac attaagtggt gtttctaaag acgaaaaacg
    35521 aaaacgggca gaagatgcat tgcaccgagt cggcttgaca aatcatatgc ataaaaagcc
    35581 aaatcagtta tctggtggac aaatgcagcg agtggccatc gctcgagcac tagccaatga
    35641 cccagatatc cttttgtgcg atgaaccaac cggagcgtta gatacagaaa caagtatcca
    35701 gatcatggaa ttgatccaag agttatcgaa agaaaaatta gtgatcatgg tcacacataa
    35761 tcctgaactg gcccatcaat acgcagatcg aatcattgaa ttttctgatg gtaagatctt
    35821 aacagattcc catcctcaca tcgaacgacc aaaagatgat caatttaact tacgcagaac
    35881 aaagatgagt ttttggacag cgttaaagct ttccttcaac aatatccgaa caaaaaaagg
    35941 acgtactttc ttgacctcct ttgcttccag tattgggatc atcggaatcg cgatcgttct
    36001 gtccctttct tctggattcc aaaaacaaat cgataacacg caagctgaaa cgatggcgaa
    36061 atttccgatt actatttcta aggtaacgac taaccagact cgtgacgatg ccggattggg
    36121 tgcaagcaaa gcggattatc cagacagcaa aacgattact gcaaaagtca gcgaagaaga
    36181 taaagcacag cacacgaata agattgatca aacatacgtc gattacgtaa cagacatcga
    36241 tcctaactta agtaataata tcggatttac ccgtactaca ggaatcaatc ttttacgtga
    36301 tgtaaatggc aaagtacagc ctgtcagctt ctcgaatcaa aatcctgata cggaatctct
    36361 ttctttatct agtacgatgt cagcaatgac aggtgtggga gtgtcaagtt tccctacaca
    36421 gcttgacact agcaaagaaa actttttaaa agacaattat tctttacttg ccggaagtta
    36481 tccagcctca gcaacagatg tcgtgctgat cgtagacggc aataataata ctaatatcaa
    36541 cgcattgaag aatcttggat ttgatgtgaa agaagacgaa aaacttgatt ttgatgatat
    36601 cgttggtaca acattcaaat tagtaaacaa caatacttac tatacaaaac ttccaactgg
    36661 gaattttatc cctaatacag attatgatgc gatgtatcag aatgcttctg atgaattgaa
    36721 gatctcgggg atcctacgcg tgaaatcttc ttctacaatg aatctcttat ctccaggaat
    36781 cgcttatagc gatcaattaa cgactcaaat cgtcaacgaa aacaaagaat cagaaatcgt
    36841 caaagctcaa agagacagtg gtgtaaatgt cttaactact gaaaaagttg acgaaaatgc
    36901 caaacaaaca ttgcttagtt atttaggtgg agacagcttg ccttcaagta tcatgattta
    36961 tccgaacaat tttgaagaca aagaaaagat cttggattat ctagatgatt acaataaagg
    37021 caaatcagat gaagataaaa tcatttatac tgatttagct ggaacgatga ctgaactgac
    37081 tggcggattg atggatgcta tcacttatgt ccttattgct tttgcaggga tctctttagt
    37141 aacaagtatg atcatgatca gtatcattac ttatacatct gtgattgaac ggacaaaaga
    37201 aatcggtgta ctaaaagctt taggtgcacg taaaaaagac atcactcgcg tatttgacgc
    37261 agaaacgtgt attttaggta tttcttctgg gatattaggt gtgtttattg catggctagc
    37321 tacgttccct atcaatagca tcttatacaa catgacggat ctaaaaaatg ttgctcaact
    37381 aaatcctgtc catgcgatta ttctagtgat cgtctctact atattgacga tgcttggcgg
    37441 tcatcttcct gcacgaatgg cagcgaaaaa agacgccgct atcgctttgc gtgcagaata
    37501 aggttgtgac aaccacattt agatttgagt cataagagcg ctgaaatagt agaaaacagc
    37561 aagaaacgag gaagtaatat gttccttgtt tcgcgctgtt ttttttaatt attttttata
    37621 attctggtat acttttcttt cctttgtacc acaactcttc tggcgtatac ctgtcttttc
    37681 catttatgaa tactgttcca tctgcttcaa tcgttacttc agtcccaatc cacatattac
    37741 gagaaagtgc gagaagattt tttctttttc ctcttccttt ttttccaaat tgcaaggcat
    37801 cggttatctc ttctgtccaa tgagatttca cgtattttac ttctccgttt tcaaatgtaa
    37861 ctttcaaaat attcgctata ttttccactt ttactgcttt aggaaatgac tcctccattt
    37921 ttttcacttt ccttcctcca acactaagta tgcgctttct tttagtgata agtatatcat
    37981 agtttattct attatcaaaa aaacgcatcc attccattgt agaatacttt accgaacaag
    38041 ttgaattgtt ttcctctttt tcacctttta ctatagatag gtaaagacaa ctaaggagga
    38101 atctctcatg acagatcaac cgtatgattt aagaaaagtc atcgaagaac taaaaacact
    38161 tccaggtcaa tatcacgaaa cagatattga aatcgatcct gaagcagaat tatctggtgt
    38221 ttaccgttat atcggtgctg gcggtacagt aaaacgtccg actcaagaag gaccaactat
    38281 gactttcaac aatatcaaag gtttccccgg cacacgtgtg aacatcggaa caatggctag
    38341 tcgtaaacgt gtaggtgaaa ttttgcacca tgattatcga acacttggtc gtttcttgaa
    38401 agacgctgta gaaaatccaa tcaaacctgt gaaagtagac aaagcagacg ctccagcaca
    38461 agaagtcgtt catctagcta ccgatgcaga cttcgatatt cgcaacattt tgcctgcacc
    38521 tacaaatact cctgaagatg ctggtccata catcacaatg ggtgtagtct taggatcaga
    38581 tccagaaaaa acaatgagcg atgtaacgat ccatcgtatg gttctagaag ataaagatac
    38641 gatcggtatg tacatcatgc ctggcggacg ccacattggt cacttccaaa aacaattcga
    38701 agccttgaat aaaccaatgc ctatcactat caatattggt ttagatccag caattgccat
    38761 tggcacgact ttcgaaccac ctaccactcc acttggctac aatgaactat ggtgtgcagg
    38821 agctttgcgt aacgaaccta ttcaaatcgt tgatggtata gcagtcgatg aagtgggtat
    38881 tgctcgtgct gaattcatca ttgaagcaga aatcatgcca aatgaaacaa tgcaagaaga
    38941 tatcaacacg aactcaggaa aagcaatgcc agaatttcct ggctatactg gggatgctaa
    39001 tccagctgta caagtagtga aagtcaaagc agttactcac cgaaaagaca atccaatcat
    39061 gcaaacaacg attggtccca gtgaagaaca cgtatctatg gccggtattc ctacagaagc
    39121 aagtattctt gccttggtcg ataaagctat tccaggaaaa gtagtaaatg tctacaatcc
    39181 tcctgcaggt ggtggtaaat tgatgaccat catgcaaatc cgtaaagaaa acgaagcgga
    39241 tgaaggtatt cagcgtcaag cagctattct tgctttatca gccttcaaag aattgaagac
    39301 agtcatttta gtcgatgaag atgttgatat tttcgacatg aacgatgtag tttggacttt
    39361 caacactcgt ttccaaggag ataaagatat catcgtgatc ccaggaatga ggaaccatcc
    39421 attggaccca tcagaattac cagaatataa tcctggctct attcgtttcc gtgggataag
    39481 tgcaaaaact atctttgacg gtacagttcc tttcgatatg aaagaacatt ttgtacgtgc
    39541 aaaattccaa gaagtagaag attgggaaaa atatttgaaa taatgaatga tctgcaactg
    39601 ttttgacatc ataaaaagga gtgcggaaaa tggaacaatt ggcacaacgg aagaaaaaaa
    39661 tcgtgattgg tgtaagtggc gcttcaggca ccatttatgc catcaaccta gtgaagaaac
    39721 taaaagaata tccgatgata gaaacacacg gaatcatcag tccatgggca aaacagaact
    39781 taaagctgga atccgactta tcactaactg aattcgaaag cctgtttgat taccattatt
    39841 caaacaaaga tttaggtgct gctgtcgcca gcggatcatt tttgaccgat ggaatgatca
    39901 tcgtaccggc aagtatgaaa acagtcgcag gtatctctgt tggtttaggc gacaacctga
    39961 ttgcacgtgc tgctgatgta acaatgaagg agcaacgaaa gttagtcatt gttcctcgtg
    40021 aaacgccatt aaatgccatt cacttggaaa acttgactaa attagcacga ctaggtgtgc
    40081 aaatcatacc accaattcct gctttttata atcagcctca aacgatccaa gatcttgtta
    40141 atcaccatac aatgaaactt ttggatcaat ttgaaattgt aaatgagcat tcaaaacgtt
    40201 ggcagggtga ttaatatgga aaaagaaacg atagttgaag taaccaaact aggtttcacg
    40261 atccaagctg ctgttaaagt aatcggtaaa gacttattga tcactttaac aggcggagat
    40321 acaccacata tcggaacagt cactacattt tctcgtgata cagagatgca aactgtacgt
    40381 ttccctagcc acgatggtcg gttccataaa gacgatgtct tagccgaaaa aatagctgtg
    40441 atcatcaaaa ctgccgttcc gggaagttgt acgatcactt ccggtatcca tgttgaccat
    40501 atctccaatg cacaaatcaa cgcctctttt ccgatgtcag aagagttagg ttacaagatt
    40561 ttagattggt tggaaaaaat agatttccat atcaaagaac cagtttatta taaagatggt
    40621 gaaaaaccat tatgaaagaa gaggttgtga aatcagcgtt atgacctgag tatgagagaa
    40681 aaaaatggaa aaatagcttc tcatattttg ccgtttttga gctaataccg agggacagct
    40741 gattgaacgc cgtttatcaa gaggttgtga taaagccgct tcgtttcgag tagtaagaaa
    40801 aattttgtaa acatgggttt ccacattttt gcataaattt gacttactac cgagaaactg
    40861 gcttttgaac accgtttatc aagaggttgt gacacgtctt ttgtcacaac ctcttttatt
    40921 tttgcttcac tgtaactgct acaatatcac cgatttcttt tccgatgttt ttacgaatat
    40981 cttttcgtag tccaaggatg tagcagactg aaccatctgg atttttcacg cccatattca
    41041 cgatactgcc ttcatatggc acattgtcaa aagttgcttg gactttaact cttccagcac
    41101 cgaattcttt tcttatatca tacggaaaaa taatatatgc cccgcccttg ccgacttcgg
    41161 aagcatagat ttttgattca aaagaataaa tttccctcat tttatttctc ctatttttta
    41221 catctagtat agcatagcaa aaaaaagaag gaactgtgac aaaagtcttg tcgcagttcc
    41281 ttttttcgaa taaacggtgt tctcctgcca actcctcggt cacaagtcac aatagtcaac
    41341 aaacatgaga agctgttttt tgaaattgct ccttgtgact cagagttaaa cggcaggctc
    41401 acaacctctt ccttaaacgg tgttcaaaag cttgcatcta cggcactaag cccaatcaga
    41461 tgaaaaatat ggagtgctat ttttatctga ttgttcttac tgcttgatgc agagcagctt
    41521 tttcacaacc tcctacatgg tgttcaaaat attattcgcc ttttgcttct ttcactaatt
    41581 ttgcgaatgc ttgttgttgg aattcagcag ctaaggcttt cgtacgttgt tcttgctctg
    41641 ctttgctcat ttttggattt tcagtcattg cttttaccat accgtcttga acataagctt
    41701 ttgcttcact ttccatcgta ctttgctgtt tcttcactaa ttcagctaac ttggctgctt
    41761 ggtccgtact taattctacc catgtctctg ggattttgaa tgtattcact cggctgtcat
    41821 attcgtgatt gttatcagca atattgaacc agaatttata catgtcgttt ttgtattccc
    41881 aataagtagt tttcgtcact ttttcagcat cgccgtctgt cttttctact ttatttgttt
    41941 cgttatccgt accagttgct tttggttttt cttgtttttc atttgttcgg taaagataca
    42001 ctttttcttt tccattccct aaagctttat acaaaagcat atctgctcct tgggaatcag
    42061 cactggaaac aattttttct gtttttgttt ccgttacttt ttccattcca aagtgattgg
    42121 acaaattagc gacgatcaaa cttagtgaag cgacgaagat tagtccgaaa atcaaagata
    42181 aaaaggtttg ccatgttttt ttagcgaaca cgttcgttaa agcaaaagca agcaagctga
    42241 caatcaaaac tccaataatc atgcattatc ccccgctttc attagaacag gttctttttt
    42301 cttcaataaa aaggcaataa taaagccaag aatcccaaag atgatcgcta cgataaacgc
    42361 ggcatggtaa cctgacagtg tggcattgat tgcctgatct ttataagcta atggcgtatt
    42421 atccaataca gatttgcttg ggatatttgc ttttgtcaca ttcgtcaaca cactgatcaa
    42481 aatagctgta ccaatcgagc ttgcgatttg acggaatgta ttatttaccg ctgtcccatg
    42541 actgatcaag ttatttggca atgcattcat accagaagtc gttaccggca tcatgaccat
    42601 ggagatccca aacatacgga tcgcataaag gatcacgata tataaaactg gagtcgtttt
    42661 tgtcaagaaa gcaaatggtg cagttgccgc tgtcaaaatg aacatccctg tgatggctaa
    42721 acgtttcgcg ccgtatttat cgaaaatcgc acccgtcaca ggcatcatag cccccatgat
    42781 caatgcaccc ggcaacaaca tcaagccaga atggaatgct gattctccac gaatattttg
    42841 aatatacaat ggtacgacca tttctgcccc taccatcgcc atatttgtta caccagctaa
    42901 aacagctgca atcgtgaatg tagatgattt gaatacacga agttccaaga atggatgttc
    42961 caaatgtaat tgacgccatg agaacaaggc gatgaaaatc acaccaacaa ctaagaaacc
    43021 aattactttc aagcttcccc agccgtcatc tcctacacta gaaaatccgt aaagtaaact
    43081 accgaatcca atcgttgata aaatagcgga taaaatatca atgctaggat ttgacaatgg
    43141 aataacactt ttcattagga agaatgctaa aaccaagaca agaacaacga ttggcagtac
    43201 cataccaaac aagtcacgcc aatggtagtt atcaatgata taaccagata atgtagggcc
    43261 taaagcagga gcaagtccaa taacgatccc tgacatcccc attgctgatc ctcttttttc
    43321 tggcgggaaa atagatagca tgatattttg caataatggc atcgatactc ccacaccgca
    43381 agcttggatc aaacgaccga ttagtaatgt actaaaatta ggtgctgtaa agcaagtaat
    43441 cgttccgatc aaaaagatcg tcatggcaga aagatataaa tttcttgaac tgaatttatt
    43501 gatcagccat gctgttattg ggatcatgat cccgttgact agcaagaaac cagtcgttaa
    43561 ccattgcaca tcagacgctg aaatatcgaa agctttcatc aatgtaggaa aagctgtcgt
    43621 caataaggtc tgattcaaaa cggtacaaaa tgtaccaatt aataagacaa caactaaaag
    43681 tgtccgatta tatggttttc cgtaaatatc tacgggttgg ttgttactca tatttctcct
    43741 tctttctgaa ttttttctga aactactaga atactttagt cctaaattcg ctatttgtca
    43801 acctacttga cacataagtt aatacggata taattaaggg aagcaagagg acaaaaggag
    43861 tgacaaaaat ggttggggct tcccttaaac gtttgttgga aaatgatcaa ttggttgttg
    43921 gcatcagtga attaagtgat atcgtaggtg tgtctccacg tcaattaagg tattgggaac
    43981 aaaagggatt cattcgttcg atcgaagctg atgcgaattg tcctagaaaa tatcgtttac
    44041 ctacagtcat aaaagtagaa ctgatcaaaa aatatttaga tgacggattt actttgtcaa
    44101 aagctgcaga aaaggcagaa atccgccaaa agaaaatgca ccatgtccgt aaagtttttt
    44161 caaaagcaat caaagatatc gaattgatcg acgaacgcta tacgatttta caaatcggta
    44221 acttcaaaga agagaatgct aagatgtaca tcattcatga caacgagaca gacgaattaa
    44281 cttacaagct ccttcctgtc gatgaaaaag ctgactacga acagttgtta aaagaactct
    44341 aaacgccact aatctcctaa gtaccaagct ttttaataag tagatgctac ataaatactt
    44401 gaaaaaaggc ctgtttgaac ataagaatat ccgaacggtg atctgcgttt ctttcatata
    44461 gaaaggaatt ctccatcact gttcggatat ttttttattt ttttcggtta ctttcttcta
    44521 atacatctgt tagccaattt gcatattctg tttcccgatt gatcgcatgc gctaaaatca
    44581 ggtagtgtcc gtaattttca tgtttttctt tttcagtagg aaagatcgtt ttttttcgct
    44641 ctaatagatg aagtcgtttt tcttcatgaa ggtcacgctg ctgctgaata atttctacta
    44701 atgccggatc attcacgtct ttgacgaaat acaatttcag aacaaattcg tctcgattaa
    44761 ccggtagttc attggtgggt gtatgaatcc actctgccaa ttgttccttc ccttcttctg
    44821 ttaattcata aactttcttt tccaattttt cacctgtgat ctctacttga tgctgaatga
    44881 ttccttgctc ttccattttt gcaagttcag gataaatctg actatgtttt gcttgccaaa
    44941 attctcctat ttcatttttg aacgattgat tcaattcata tcctgtcatc ttcttcttac
    45001 ttaataaccc taacaaaata tatcgaagtg tattttttct tgccatcagt tttccctcct
    45061 tgacaaatct ttaaatccat tctatcataa atgagtaatc gaaaacatgt agtttattac
    45121 atgttttaat ttataaggag atgcttaaac atgaaagaat ttaaagaatt ggaagatttt
    45181 attggaactc actttatcta tacgtatgac aatggttggg aatatgaatg gtatgccaaa
    45241 aatgaccata ctgttgatta ccgtatccat ggcggaatgg tcaaaggccg ttgggtaaaa
    45301 gaccaagaag ctgatatcgt taaattgacg gacggcgtat tcaaaatcac ttggacagag
    45361 ccaacaggga cagacgtggc attggacttt atgccaaatg aaaagaaact tcacggaatg
    45421 atctttttcc ctaaatgggt tgaagaacat ccagaaatca ctgttacttt ccaaaacgaa
    45481 catatcgcag aaatggaagc agctcgtgaa aaatatgaaa cttatccaaa attacttgtt
    45541 cctgaatttg ctacgatcac ttatatgggt gatgcaggta tagacaatga agatgttatt
    45601 agcgaagaac catacgatgg aatgccagat gatatccgta gcggaaaata cttcgatgaa
    45661 aattataaac gagtaaaata aggttgtgaa agagaggttg tgaaatcagc gttctgacct
    45721 gagtattaga gaaagaaacg gaaaaatagt tcctcatgtt ttgccgtttt ttgagctaat
    45781 accgagggtc agctgattga acaccgttta tcaagaggtt gtgaaatcag cgttatgctt
    45841 tgagtaataa gaacgctagt tagaaaatag cttttcatat tttctaggct agtgggctta
    45901 ttaccgagaa gcagccgttt gaacaccgtt tatcaagagg ttgtgaaatc agcgttttga
    45961 cctgagtatt agagaaacaa atggaaaaat agttcctcat attttgccgt tttttgagct
    46021 aataccgagg gtcagctgat tgaacaccgt ttatcaaaga ttgtaacaac tgcatattca
    46081 cacagttaaa ttagtgactt caaaatgaaa taatgctccc agcaaaaaat taggctggga
    46141 gcattatttc gttattctgt tcatcaaaaa tcagcgtttt gattccattt catcacaagt
    46201 tcctcctcat ttactgcttc atctttttgc tgtgtttgaa ttgtaaaacc ttgtgaaaga
    46261 tagaaatgaa tagctgattg atttttttga tagactgtca aagtcagtgt tttattggtt
    46321 tcttttattt ttttcattag ttgcgtaccg attctttgtt gccggtattc ccttttcaca
    46381 aagattcctg cgataaactg atcaatcacc ccagcaaaac caataatttc ttgatctatt
    46441 tctgctaagt aaatcactgc atctggtaaa gctttcctaa cagattctac ttgattctcc
    46501 caataagttg atggaatgaa ttcatgagaa tccaagttag catgcagcca aatcgataga
    46561 acagattcca gttctttggc agacaatttt gttgttgtgc ggatcatttt ttctctcctt
    46621 acttattcat tgattttaaa ataaaaacca tttttttgaa gctcttttac aagttttcgc
    46681 ccctcaaaaa agtatatctt ctcttgtttt acttttctaa taccaaaaga aacagcaact
    46741 ttaggatcat cagctgaaac gattcgataa gttccaccag gcaattgatc cagcttgact
    46801 ttcccatgat ggtcgctttg tactgaaaac ggcacaccat ttctagtaag tgtttttttc
    46861 ttatgtttca aaatgaatga actaccattt accggtttcc ctgacgaatc actaataata
    46921 aatgaaaaat caagcacttt tttacttaat ctatactgat agattagtcg tccgataaac
    46981 actaacagta tgactacagc tattatcgtt cctgcaagaa taaaccattg ccgcatggtt
    47041 ctttcctgat ttccttttcc ttcttctttt tttaccgatt cgttataagg aatccgatgt
    47101 cctgtcacta gcaaacgatg cgtgttgatc atatacggcg tacatgtaag caaggtaact
    47161 aagtcttctc cttctgaaat cgttagaaca gacgtgtcat ctggcagtac cacttgtata
    47221 tttttaactt gataagccaa tttctccccc aaaacagtca aaataaacgt gtctccgttt
    47281 tctaaacgat ctaattcggt aaataaccgt cgattaggta aaccgctgtg agcagagatc
    47341 actgaatgcg tcgaatttcc accaagcggg aaagaggttc cttgcaagac gcctgctcca
    47401 ttttcaagga tcctaccatt gagccgatca taaagtgaaa tatttaattg gatcttaggt
    47461 atattgatac ttccgatcag ccattcctct aattggctgg atgttgtact ttcatttctg
    47521 ttcttttcat tgaaaggatc agtaccagga ttgaatcctt ggtcagttaa tcgttggttt
    47581 ttctcctcca ttttctttcg ctgcacttca atttcagctg cggtccgttt ttgtacttgt
    47641 tcgatacgtt tttgatcaat aaaactattt aaagaatcca cataaaatgg atataaagcg
    47701 atcagtaacc ctacgacgat acatattaat aaaaacaaac gaaacaaaag tcgacgagac
    47761 tgtttttgct tactctgctt cacatgtgtc ctcccttgca agtttttttg ttctttcttt
    47821 tattatatgg gttcaggaaa aaaatagaaa atgaaagccg atgaggttgt gaaaaagctg
    47881 tcctgcatca agtaataagt acagcccaaa aaaatagcta ctcatatttt ttgttgggtt
    47941 gggcttatta ccgcagatgc aagcttttga acaccgttta aggaagaggt tgtgaaaact
    48001 gcgttatgct ttgagtaata agagcgctag tcagaaaata gcttctcata ttttctaggc
    48061 tagtgagctt attaccgaga agcagctgat tgaacaccgt ttaccgagag gtcatgaaaa
    48121 agctactttg tttcgagtat taagaaaaat tctgtttcaa aacaaggaga tgcaacaaaa
    48181 cttatgtcgc atcctctctc cttagaactt tcacttatgt ttttcttgta aaattcataa
    48241 atattttcat gaattttcta atttcttgcc tacctctcgc ataggatata tgatgaattt
    48301 atctaaagtt tgcaaaggag ttcgacaatt gaaaaaatat ggcccatttt tagcaatttt
    48361 tttcattgct ttggcatttc tcatgcctca tttattcaca cataaactaa ttttgggtgc
    48421 tgatgcccca ttccattaca atcggttcta tgatgccgcg caacaaatta aatatgggga
    48481 tttccattat tttccttccc tttatggatt ccagcaaagt ggcaggatcg tgaatgccgt
    48541 ttacggccca tttttcgctt atttacaagg attgatcgtg ttgcttgcag gtagctggtt
    48601 tcattatcag attctttcaa atttcattct ttatcttatt tcaggatttt ctatgctgat
    48661 tttactgaga tatgtcaatg ttcgaaattg ggtaagtgta ccagtagccg ttttattcat
    48721 gagtacgtat tctattcaat actggtctat caaccaagga ttcactagct gggggacttg
    48781 tttttatcct ttatgtatga tccctattgc tgatttcgtc cttcataaaa agttccctgt
    48841 tatcaaagtc gctgtctcag tgggacttat gacacagatc catttactgt cttcgatcat
    48901 gttagctttg atgtatatcc ctttttatct ttattacttt tttaaccaga ctgaaaaagg
    48961 aaaagcactg cttcaactga ttaagtcggt cttgctttat tttgttctga cagcaaatat
    49021 ttgggcagga ttagctattg tttacagtgg gaataagatt cttcctccct ttgttaacag
    49081 agaaatgagt caaaaggcga tagatctgga tggcagttat tggctccatt accctaaggc
    49141 ctttcctata ttgatattat caggtttttt gctttttatt ttctttcaac aaaagaacac
    49201 cttattccaa aaaatcgtgt tgtacacaag tcttgttttc ttttttcttt ctactagctt
    49261 gattccatgg acgacattga tcgaaaaaaa tgtgcctttt attagtttga tccagtttcc
    49321 atttcgattt ttcgtgccat ttacgctatt gcttctactt taccttgccc tttcactgaa
    49381 ccagtggtct gaacaaaagt ggttccgtct tttaagtata tttggcattc ttattttttc
    49441 agcacagacg atccagaact tataccagca tctggaaaag tgggaaaatg aaacatttgt
    49501 cagtcgacat acttatctat tcgatacgcc ggaagaagca aggaaaacat tcttcagcaa
    49561 agatatgtct accagcttgt tcgttttcca aaaaaccaca cctgactatc tgccaatcta
    49621 taaggagaca aaagacaata aatacgaccg gtataacgaa gaaatactag aaaacgaaac
    49681 aacttttata aaaacacatc caggcggtct tttgacaatc aagtggaaaa acactgggga
    49741 caaaactgtt catatccctg ttatcgtcta cgatcggact gtgctacagc aaaatggaaa
    49801 aacattgact gattatgaag taacagatat cgggacccca atcgtgaagc agcaaaaagg
    49861 aatcaacgag ctcacgcttc attatcaaac gccaatctat ttctatttca ttctttctct
    49921 tactttgatt ggctggttta ccttgctatg tttatttatt tatcatagat acaagctttt
    49981 acgtgcttag gcaaaaggga taaatacatc cgatcaaaaa actctccaaa cggtataatc
    50041 gtttggagag ttttatttta atcagttttt ttatgttata tgttatattt tttattcgtt
    50101 cacatctaat tcgatttcca ccccgtagtg atcactgatg attggactat cgatcccatc
    50161 aaaaatccgt tgatattttt taacctgcat tccttcaggg acgaaaataa aatctatacg
    50221 caatttttct gtattttgtt cccaaccatc tattttcttt tccacagtag ctgcttttcc
    50281 tttttcattc gcgacaacat acgaatcttg aagaagaagg caactttctc ttacagtata
    50341 ataaccttga gagtctactg gattattgaa atcacctagg aaaaaaagtg gtacgcgagt
    50401 ttccaaaaag tagttttcca agtttttcca ctcaaaataa aagccacttt ttttatctgt
    50461 ccaccaagaa aagtggcagc tcgagacaaa aatgtcctga tcatctatct ttgttttccc
    50521 aatcaagatc ttgcgtgtct gataatcttc tttcttttga aattgggaga cggtaaggac
    50581 ctgactttcc aatgtttttt tcgtaagcag tgcatttcct tcttcatatt tatcataacc
    50641 gatgtggctc atttcccaac tccaaaaata ctcttttccg tgttccttta aaagctgaac
    50701 taaacggtag gcaaaattat ctttacggat aggtacttga ttctttaccg gacagaactt
    50761 cattagcttc gcaggttcta cttcttcaga ttccagtaat tggttgattt cttgtaaagc
    50821 aatcacttca taatcttcta acaggatctt atctgctaat tcttgcaatt ttttctctgg
    50881 ttctggctca agccagctat gcgtgttgag tgtcatgaat ttcattggtt ttctccttgt
    50941 cttcatttcg aaacaaaagg gttgtgacaa aatttttgtc acaacctctc cagcaaatag
    51001 tgttctcctg ctaactcctc agtaataagc tcaatggacc aggagctatt ttttgtttgg
    51061 ctgtttttat cacttggtgc agggcagctt tttcacgacc tctccactaa acagtattca
    51121 aactgctgct tctcggtaat aagcccaacc aaacgaaaaa taggaggagc tatttttgtt
    51181 tggctgttct tatgacttga tgcaggacag ctttttcaca acctctcctt acattttaat
    51241 ggagccgatc actttaccag ctgtcactgt acctaattgc ttgatcacta cttcttctac
    51301 tttatcgttt gtaaatacga tcatgatcgt tggatctttt tcttcgtttt ggatcacatc
    51361 aagatccatc tcagctaatt tcgttcctgt tcctacttct tggccttctt tgacagcaat
    51421 ctcaaaagct ggctgattca tttggactgt atcgattccc atatggatca aaacttcgat
    51481 accatctttc gtttccagcc caattgcatg tttgctaggg aaaatacttg tcacttttcc
    51541 agcgatcggc gcaacaactt ctcttgatgt tggaataaca gcaaagccgt cacccatcat
    51601 tttttgtgag aataccggat cttttacttc agataaagga atcacttctc cagaagctgc
    51661 ggaaactagt tcttgttcta tacctaagta ttgcttacta cctgcttgtc catttcctgt
    51721 agaaaccatt tctggctctg gaatctctgc tcctgattgc agcagatctt cgatatctga
    51781 tttcaagaca tctgcttttg gtccataaac tgcttggact ccattgtctt tgacgatcaa
    51841 tcccatcgcc cctgctcgtt tccaggcttc ttcagtccct actttttctc gatcatttac
    51901 acttacgcgt aaccgagtca tacaagcatc gacatctttg atattttctt ttcctcccag
    51961 caaatgaatg atctggacca cttgctgatc tgctgttcct gttccgctgt tagatacaac
    52021 ggtttcttca ctgtcattgt cgtaatttcc gttacgtccc ggtgtagcaa agttgaattt
    52081 tttgatcaag aaatttgcta agaaatacgt aacaacacca aaagcgatca cacacaacac
    52141 gaagttgata agatctccac ctagacccgc tttgatagct aacggtgtcc gagtcagcaa
    52201 ttcgatattc ccaaatgaat ggacccgcaa tggcaagata tctgccatcg caaatgcagc
    52261 cccttggatc actgaataaa tgacatataa tggcacagca gcaaacataa acatgaactc
    52321 caatggttct gttacacctg ttagaaagac agccaacgct gctgaaaaat acattgattt
    52381 atatcttgct ttcttatcag gatcgacatt acgatacatc gcaaaagcca ttcccatcaa
    52441 gatacctgaa gaaccaatca tttgtcctac tttgaaacga gccggcgtcc agttatgcaa
    52501 cacaaactca tattgcgaca tatcccctgc acctttaaga ttcactaaat cagtggccca
    52561 agccaaccat aacggatctt gcccaaatac ttgtgtcccc gcctgtgcgc ctgataaaat
    52621 ctcatacgat ccgccaagct gtgtatagtt gataggaatc gtcagcatat gatgcaatcc
    52681 aaatggcaat agtaaacgtt ctaatgttcc aaataaaaac ggtgctagaa tcggtgcgct
    52741 ttcttgtgat tctgcaatcc ataaaccaaa attattgatt ccagcctgta cgtttggcca
    52801 caccacagca agaatcaatg ccacgattgt tgaccataag ataacaacaa acggaacaaa
    52861 gcgctttcca ttgaaaaatg acaaagcatc cggcaatttt ctataattat agtacttatt
    52921 ataagccatt gccccgacaa atccagcgat gatccctacg aatactccca tattcaaagc
    52981 tggtgcttcc aatacacttg taaaaaatcc tttaaccatg atcttcgtac cgaacagagt
    53041 gtgggtaaat gcatcttcat tcgcaagcat gtcacttgtg acaccaaaga tagccccagt
    53101 gatccgattg attaaaataa atgagatccc agctgcaaat gctccgcctg ctctttcttt
    53161 tgcccaactt cctcctattg ctaaagcaaa taaaatatga agattaccaa taattgccca
    53221 accaatattt tcaattactc cgcccgttgt gacaagcggc gtccaatcag gattgatcaa
    53281 gggaattgat ttccctatac tgatcatcaa cccagctgcc ggcataactg ctaccacaac
    53341 cattaaagcc tttccaaatt tttgccaaaa ctcaaaacta aatatctttt tcattccgtt
    53401 tagctccttt acgcaatcgg tttcgttaaa cgtattatag cgtgcgtttt cttttttgta
    53461 aatgctttat tttttatttt tctgtctata ccattctata aaacctataa tacgtgtgtt
    53521 cccttctata attttctcct aaaaatttat ttttttaagc ttttttctat gaaatatttt
    53581 cttttgtcta ttgacttgtg caatcggttg cgtttattat gaacgtataa aacagctcat
    53641 taggaggaga aaaatgaaac agatcaaacg actatttgct attgatccat ggaaaatcag
    53701 cacgacacaa ttagataaaa aaaatcttcg actgcaagaa tctttaacaa gtattggaaa
    53761 cggttatatg gggatgcgcg ggaactttga agaaacttac tcaggggacc accatcaagg
    53821 tacttatttg gcgggtgtct ggtatcccga taagacacgt gtcggctggt ggaaaaatgg
    53881 ttatccagaa tactttggaa aagtgatcaa cgccttgaac tttatcgcga tagatatttc
    53941 gatcaacgat cagctgatcg acttggcttc tttggaacca gaagactttt actgggaatt
    54001 agatatgaaa aatggtgtat tatctcgtac attcacaatc actacttcta ctaataaagt
    54061 acgcatttcc ttcgaacgtt ttctgagcat tgtcaaaaaa gaatcagctt atatctattt
    54121 aactatagaa atgcttgaag gtagcggaac agtcaaactc gtatcaaaat tggatggaaa
    54181 tgttcaaaac gaagacagca actatgatga acatttttgg aatgagattg atcgtggaac
    54241 tatagaagaa atcggctatt tgacgactaa aactattcca aacaactttg ggattgaaca
    54301 atttactgtt actgcagcaa tgcgccattt cgttaatgga aaatcagtca tccctgacta
    54361 tcacgaagat actttagcat tacatggttg cttgtctgca gaattatctc aaggtgagac
    54421 atggtcagtg gaaaaagaaa ttatcgttct tactagtaga gatattccag aagcgcagca
    54481 agcagaaaaa gctgtctcag aattaacgaa ccagacaaac aattatatcc aagcaaaaga
    54541 agagcaaaca gcggcttggg cagaacgatg gaagcttgcc gatgtggtca tcgaaggaga
    54601 cgaagaagca caacaaggta ttcgattcaa tttgttccaa ctattctcta cttactacgg
    54661 cgaagatgaa cgattgaata tcggccccaa aggattcaca ggagaaaaat acggcggagc
    54721 cacttactgg gatacagaag cgtatgctgt ccctctttat cttgctttag ccaaacctga
    54781 agtaactaag aatctgctga aatatcggca taatcaactg ccgcaagcaa tccacaacgc
    54841 tcagcaacaa ggattaaaag gcgcgcttta tcctatggtc accttcactg gtgtcgaatg
    54901 ccataacgag tgggaaatca cattcgagga gattcaccga aatggcgcga ttgcctatgc
    54961 aatctacaat tatacgaatt acaccggcga tacggaatat ttgaaaaatg aaggactgga
    55021 agttttagca gaaatcgcac gcttctgggc agaccgtgtc catttttcaa aacgagcaaa
    55081 taaatacatg atccacggtg tgaccggccc aaacgaatat gagaacaata tcaataacaa
    55141 ttggtataca aatacgatcg cagcttgggt cttgcgttac acgcgagaaa attatttaac
    55201 ttatcaaaaa gaagctgcta tcactatcag cgaagaagaa ctagccaaat ggaaagatat
    55261 cgcagagaac atgtacttcc cagttgacga agaattagga atctttgtcc agcatgacac
    55321 attcttagat aaagatctca tgcctgtatc cgatattccc acaagcgatc ttcctctgaa
    55381 tcagcattgg tcttgggaca aaatccttag atcttgcttc atcaagcagg cagatgtact
    55441 acaggggatt tatttcttca atgatacttt tacaaaagaa gaaaagcaaa aaaactttga
    55501 tttctatgaa ccaatgactg tccatgagtc ttccctttcg ccaagtatcc attcgatttt
    55561 agcagcagaa ttaggaatgg aaagcaaagc tgtagaaatg taccagcgaa cagctcgctt
    55621 ggatttggat aattacaata acgacacaga agacggcttg cacatcactt ccatgactgg
    55681 tagctggttg tcgattgtcc aaggatttgc tcaaatgaaa actgcccatg atcagttgag
    55741 attcgcacca tttctgccaa aaacttggaa agcttattct ttccatatca attatcgcgg
    55801 acgtttattg ttcatctcag tcacagatga acaagttact ttcgagttat tagaaggttc
    55861 tcctctagaa atttacgtct atgaacagtc ttattcttta gcggatcgtc tagaaataac
    55921 gctaagaaag gaggaagcaa atgtttaaag gggtattgtt tgatttagac ggtgtcatta
    55981 ccgatactgc tgaattccat tatcgtgctt ggcgaaagct tggtcaggaa atcggcatta
    56041 cgatcgacca cacattcaac gaacagctaa aaggcgtcag ccgagaagac tcactctctt
    56101 tgcttttagc ttatggcgga aaagaacact ctttttcaaa ggaagaattt gcagaattag
    56161 cgaaaagaaa aaacgattat tatttagaga tgatccagac gatcgaacca aaagatgtct
    56221 tccccggggt cgtgccttta ctggattctt taaaagaaga aaaaatcaag attgctcttg
    56281 cttctgcaag taaaaacggg ccattcctac ttgaaaaaat gggtcttaca ccttactttg
    56341 atgctattgc cgacccggca gaagcaacaa acggaaaacc tgcgccagat atcttcctcc
    56401 ttgcagcaaa agctgtcgga ctaaaagcag aagaatgtat cgggatcgaa gacgcgcaag
    56461 ccggtatcca agccatcctc tcaagtggcg ctcaaccaat tggcgtggga cgtgctgaag
    56521 accttggaga ggagatcccg cttgtccctg atacgacttt tcttacgatc gattacttga
    56581 aagaaaagtg gcatgaccat ggataatcca gagatctccg tcgtaccagt tccagagact
    56641 gaaataaaga aaatcacatt gaagaacgac tacttagaag tcgttcttct caattacggt
    56701 gcccgcctgc accaaatctt cgcaccagac aaagaaggaa aatcagaaaa tgttttattg
    56761 tcttacgatc gtttcgaaga tgttctaaca gacaaaagct tttttggagc aactgtcgga
    56821 cctgtagccg gaaggatccg ggatgcttct tggggtgagc atagattgga gaaaaactgc
    56881 ggatcacacc atatccacgg tggcacgaaa ggctggtctt tccaattttg ggaagtagaa
    56941 gttttcaaaa ctccatcatc aataggtgtg gtcttttact taaaagatga attttctacc
    57001 tatccaggac caatcactgc tacgatcact taccgtttaa caaaaaacga attagagatg
    57061 acaacctctg ctagtagcct tgttgaaacc atctgcaatc cgaccaacca tgcctacttc
    57121 aacctttcag gaaatggaac aagagacatc tatgaacatc agttaacggt ctttttagat
    57181 ggtgtgcttg aattagatca agaaaaactg cctactggaa attggacaaa aaaagaaaaa
    57241 ctgccaatcg actttagaaa atccccaaca ctgcaagaga tccttgcatg ttatccagat
    57301 ggactagatg atgtatttct tttgcatcat cctaggcttt ccaaaacttc cttacaatta
    57361 ttcgagaagc attctggtcg ccaaatgact atagcaactt ctaataaaag tatggtatta
    57421 ttttctacga ctggattcga agctgatttc tctgtcaatg gaaaacagat gcattcaaac
    57481 tacggattag caatcgaacc gcaagaaatc cctgatatcg ttcatttccc caaatttgga
    57541 tcgatcaacc tccatcctgg tcaagaacgg atcagtcaga cgatttatcg gttctctgca
    57601 caataacaag agaaaggtgt ttttatcatg gctattaccg taaaagatgt ggcgaaaaaa
    57661 gccggtgttg ccacctcgac cgtctctcgt gtcatcaacg atcatcctag tatttccgag
    57721 acaacaaaga agaaagtccg aaaaattatg gatgaactag gttatgttcc taacatgact
    57781 gcccgcaatc taggaaaacg catttccagt gccatcggcg taatcttacc ccctcttgat
    57841 tcaaaagagc ggatcggtaa cccattttat cttgagatca tggaagcaat caacgaagaa
    57901 gcgcggaatt atgatatgac tacagcaatc gctactgcta aaaattttga attgctgtta
    57961 gagaacgtcc agcgtatgca tttacaaaaa caagtagatg gttttattct agtgtattca
    58021 gatagtcaag atactgtcat tgattattta taccaaaacc acatcccttt cactttgatc
    58081 ggacagcctt atcatcatga gaacgaaatc gtttatgtag ataatgataa ccagcttcta
    58141 ggtaaacaag caacagaatt tttgatccag aatggacata agaatatcct gtttgtgaca
    58201 aacacgactc atgaaagttt gtatttcgaa cgatatttcg gttatcaaaa agcaatgatg
    58261 atggctggtc ttcctgcgtt atccagtgta gtactagagc atccggagga ttatctgtcc
    58321 tttgagaaaa cgttgaaaga aaacgaagcc acagcattgg tggtcattga cgatatcttc
    58381 gcccttcgca cgatgcagtt ggcgcaaatg tatggctatg tcattccaga gacactctcc
    58441 gtcattagct tcaacaactc gatcttctca acattaacac acccttacct tacaagtatc
    58501 gatatcgata tctccgaatt aggacgtgtc gctatgcaaa agctgcgcga attgatccat
    58561 gaagaattga gcagtggcgt acgtttggtc atccctcatc gcttgatcaa aagagagaca
    58621 gtcgttcctt tagaaaaccc atactaaata gctgactcac taaatacgct gaccatttat
    58681 cctatggtca gctttttatg taaaagaaga tactacttct aacacattgt ttatctgtaa
    58741 aaaagagcgt gggacaaaag taaagaacac ttttgtctca cgctctaaac acgtataaac
    58801 ggcggaagca gaagcaactc cttcggaaat aagctgaaat tcacaaaaat ttaaaaagca
    58861 attttcttga gtttcttctt atttcttgga gttaaacgct tctgtcccag cctctttttt
    58921 ccttccttca attttttaca cgtcgacgat tcaataaaaa accgcctaat attgtaaaga
    58981 caggtgcaag aatcgagaaa aaggcgaatg gcaagtaatg caacgcgcta actttcatcg
    59041 ttcccataat gaatgtgccg ctgactcccc acggtacgag agaattgacg gtcgcacctg
    59101 aatccgctag tgttcgtgtc aaataggttt ttgataagcc aacgtcatca aaagaacgct
    59161 tgaatgtttc tcctggaaga atgatggaca gatactgttc tccaacgatc agattgattc
    59221 cgatacagct caaggcagta aacccgacta aacgagaagg tcggtccatc ttttctttta
    59281 attcttgaac gatggtatca acgatcagat atttgatcag taacccacct aatgccaatg
    59341 caagtaaaat caaactagca gaacctaaca tactcatgat cccgcctcga gaaagcagtt
    59401 catctagctt tggatcaggt gtatttgcga cataaccatt catcaagatg tctgctgctt
    59461 ttccgaccgt caaacttttc tcatggataa aagaaagaac gagagcagct gtcgatcccg
    59521 ctagtaatgt agggatagcc ggaatttttt tgattgcccc cccaaataaa ataactagtg
    59581 gaatcaatgt ccaaggagag atccaaaagc tcgctttcat gttttggatc atttcattga
    59641 tactagctag atcggctgaa tgactgttat gtcctaatat cgtataaaaa atcaacgaaa
    59701 ggacgaatgc tgggaaatcc gtataacgca taccagcgat atgttcgaat agattaactc
    59761 ctccaatacc cgctgccaag ttggtcgtat ctgataaagg cgagcagtta ttccctaaaa
    59821 aggcaccgga aacgactgcg cctgtagtca ttgcatcatt gaatccaagt aaatgaccga
    59881 tccccaaaaa agcaattcca atcgtcgaaa tcgttgtaaa tgaactgccg acagtcactc
    59941 cgacaattgc acaaacaaga aatgctgtcg gtaaaaagaa acgcacagaa acaagtttaa
    60001 atccataaac cataatcgta gggatggttc cagataaaat ccatgaagca actaagacac
    60061 caatcaaaag aaaaatcagg attggaatga tccctggagt gattcctttg atgatcccgt
    60121 catggatctc atcccatgtg aactttttaa atctgccata aaacaacaaa cacatgaaag
    60181 ctgcaaggat cgggatatgt ggcgagagct ggaatccgat gatcagtact cctaggagtg
    60241 ccaacaacac gatcaataca gcgatacttt cttttaaaga aatattttta ttcatcgtcg
    60301 atctcctatt tcaaatgaaa aggccctgcc atgaaaaaac tattcacttg gcaggacctc
    60361 ctactaaatc agcgacaaaa cgtcggctga aagacttatt tttttatttt tcttctaaac
    60421 ttttttctac ctcaatcccc caagaatctt tcttgaagtg attgatgatc aatggaataa
    60481 cgaacatgac cactgtgata gctgctacta ataatgcatc actcaatgtc gctgtaccta
    60541 atgtagcaaa tacgacaacg atgatagaga agatcagcat gcagctgact acccaagcta
    60601 atccgtttcc gtttttacca attcggtaag gacgttcgaa ttctggatgt ttcttacgca
    60661 ttttaagcaa tgaaacagca atcaaaatgt acacgataca ataaataaca gttgtagcat
    60721 ttgtaagtgt caagaataca gcacttacgt catccattac accataaagc aaagcaaata
    60781 atgaaataac gattgattgt gttagaacga catttctaga tacgccgtat ttgttttctt
    60841 tatggaatcc gaattttggt ggaaggaatc cttcacgagc tacttggatg attgtttttg
    60901 atggtccagt aacccaagct gataattgta aaagcacacc aataaatacc atgaagctga
    60961 agatatttcc gatcacttct ggtaagccta ggatttgaca gtcaatcaag ataggctgcg
    61021 tgatatttgc taattccatt tttccatctg gtacgacatt tgctacaagc atcgcattga
    61081 tgacattcaa taaaactaat ccgatcaaag cgataaatac gccttttgta taattttttg
    61141 ttgcgtcttt caaacgaggc atgtaaacag aactcatttc gatcccaaca aaaataaatg
    61201 tgataccagc taagtatttc aatgaatcaa tatgttccaa gtcagggaaa gcttttgacc
    61261 atgaaaagtc acctagatag ccgtttgaga ctagtccgac tttgaaggct gccaaaacac
    61321 ctaaaacgaa catgatgact actgggatat atacccctag ccatacaccg atgttcccgc
    61381 cgacttttgc catatcgaat ttcaagttca agatcgtgat gatccagtag ataactaaaa
    61441 tacaacctaa aacgaaccag tgattattgc caagttctac attaccaaat gtgtttccta
    61501 acaatggtcc taaagtagaa gcgaccatta ccatacctgg gaacatttgc acccataata
    61561 gccatgcaac gacaaatccc catttgctgc ccagtgctgt ttttacccat aactgaggac
    61621 cgccttcttg aggaagcatc gtggaaagct caccggaaac cattgatatc ggaccggcaa
    61681 aaaacaaaac tgcaaaaatt gaataaaaaa tcaatgtcca accgactgcg gctaacgtag
    61741 gaatactccg aaccgttgca cacagtgcca ttgtcagacc gataaaggtc ccaagaccca
    61801 ttttacttac ttcagattta ctcaccgttg acactctcct tgattttttg gataaaataa
    61861 cggtgtcttt gaagtagttt cagcaataaa cgaaacaatt cagcgaatat ttgaggggat
    61921 tctttgagtt tattgcttga agggtttctt caaagacaac ctcaaaacaa agggatcgaa
    61981 gagcttaggt ctccccttgc tcttcagatc caaacatgcg tcagaaacag ttagtattca
    62041 agctgttttc taacatgatt accttgctta ttttgcttcg cttgccaata attggtctgc
    62101 gtagattttt tccaattttt cttgaagagc tgctttgatt ttttcagcat attcttcaaa
    62161 gtgttcttct ttgttcatgt atggtgtcat tacgctggca cgcaatacag ttacttttcc
    62221 ggcacggttc cattcttcat ctgagaatcc tagttggttc acaaattgta atgggctgtt
    62281 gccatagtct gggatagcaa agtcagtatg tgaagttaag aactcattac cgtaaatgct
    62341 tcctttcacg tatgaagaat aatcatatac gtcatggttc aatttattca ttgcaactaa
    62401 gtcatcgttg cctttttctt tgaatacata gtctaccata ttgaaatctg gataagttaa
    62461 tggatgaact tcgatttctt tgtctcctac tttaaatgac aagtcattca agaagttgta
    62521 gaaacgatgt gcaccttcga ttgatgcacc cattaattta ccatatcctg tgacattcaa
    62581 aggtaagaca tggtgtgctg cccaaacgct ggctgctgtt gcccctgctt ttgaaccttc
    62641 caagatataa gccccaagta atgctgggat atctgcgcct ttttcaaata catatgtcgc
    62701 aaagtaagag ataacgtctc tcatgcggat atctttgatg acgataccac cggcagaata
    62761 tggaacatag cccattttat gtgggtcaat cgttacagat tctgcttctt cgattgcttt
    62821 atatgcactg tgtacttctt ctaagatata atctttgttt tctgtaaaga cattgtattt
    62881 gtaatgaaca tcttttaaat cttcaaatgg aatgaagttg ttgtcttcgt ctaagaaaat
    62941 cgcacggccg tatccgccat aagcagcatc tacgtgtaag tagaagtaaa taccgtcttt
    63001 ttctaatacg cgacgcaatg caacgatttt atcgataccg tcgattgctc cttcttctgt
    63061 tgatcctaca acaccgacta cacctaggat tggtgttttt tcagctgcta gaccacgaac
    63121 gattttttca agttcgttga tgtccatgcg atagttgtgg tcaactggca ctggaatcac
    63181 ttggtctaaa ccgataccga tgatgtcggc agcttttagc catgaatagt gtttagtttg
    63241 tggaaccaac cattttccta atttttctaa atgttttccg ctacgtgctg agtgagcttt
    63301 gatttcgtcg attttttctg ggacgctgtc taacagattc atgatttctt ctgttgacaa
    63361 gttcattaat tcccaatcgc tttttccagc aactagttca ggtgtcactt ctttcattgc
    63421 aagcggcaat gatttgatgt tgcgggcata ccaaagtcct tctaagtttg ctaaagaacc
    63481 atcagcaacg atgtggcccc agccatcttt atagctcatt aattttgcaa attccattcc
    63541 tacttcttct tccatttggc ttgttgcagg agaagattca taggcaacgt tattaccatt
    63601 ccatagcata gcaaaattgt acgctagtaa agatggcatc aatgtttcag agttcatatg
    63661 accccagtaa cgtccggcat tatgccaagg aacggaatgg gtacgcatcc gcgctgaaat
    63721 ttctgataga acatcctttg ttttattcac agtgtgttca aaactagcac tgcttttttc
    63781 ttctggcgta ataataggca tgtcttgagg catgtagttt tgacgccagc ctaaatgttc
    63841 atccaccaat tcattcaaca aagctttata gatttggccg ttctcagctt tgtccccaat
    63901 gaatagggca tttaggttta gatctttcga caatgattca ctcatagtga aaccctccta
    63961 aaaaaatatt taaattttgt cgagccctac attacacctg ttcttctatt ctgtaaacta
    64021 agttttggcc tgatttttaa tcatatttta atatgtatca attatccgaa ttgttcacac
    64081 ttttgaaata attaaaaaaa acgagggaat ttacaaatgt aaactccctc gcaaagattg
    64141 tattaacgac aaccagcgtt ctattttagg atgggtttca aaattggaat gttgtaatag
    64201 tatttccctt tttcaaggta aaaacttact aaattctaat caattacttt ggccaaaaag
    64261 taatttttct taccttttcg aataaccaca aacttaccat cgaattcatc ggatggattt
    64321 atgacaaaat ttaaatcggt aacgcggtca ccgttaatac ttatagctcc gtttgaaaca
    64381 tcttcacgtg cttgacgttt agatggttca atttttgtgg aaacaagcag ttccacgata
    64441 ttttcaggtg tgcttgaaat ttcaacgttc ggcattttac cgaatccttg cgcgatttct
    64501 tccgcattta gttctttaat atttccagag aacaatgctt gcgttatttt ttgcgcttct
    64561 ttcaagtctt cttcactatg cacaaatctt gtaacttctt ctgccaaacg gcgttgtgct
    64621 tcacgtttct caggttctgt ctctactttt ttcgctaagt cttcgatttc ttcttgagac
    64681 aagaaagtaa agaatttcaa gtatttcact acatcgcgat catcttgatt caaccagaat
    64741 tggtagaact caaatggtga agttttcttc ggatcaagcc aaacggcacc gcctgcagtt
    64801 tttccgaatt tcgttccgtc agccttcagc atcaatggga tcgttaaacc gaacgcttct
    64861 gcttctggtc cttctaattt tcggattagg tctaatccag ctgtgatatt tccccattgg
    64921 tctgctccac cgatttgcaa ttgcacatcg tatgttttat gcagatgcaa aaagtcgata
    64981 gattgcagga tttggtaagt aaactctgta aatgagattc ctacttccaa acggctggca
    65041 acgatatctt ttgctaacat cgtgttgatg ttgaagtttt taccgtagtc tctcaaaaat
    65101 tcaagtaaag agatttttga caaccagtcg tagttgttca caaatgtgat atttgcatct
    65161 ttaccaaaca attttctcat ttgattggaa agtgcgtcca cgttatgttg cacttgttcc
    65221 atcgtttgca acacacgttc tgttttgcgg ccgcttgggt cgccgatcgt tcctgttccg
    65281 ccgccaatca gaatatatgg atgatggcct gccaattgga atcttttcat catcataaat
    65341 ggaatcaaat gtccgatatg catcgaatca ccagttggat caacgccgca ataaagtgaa
    65401 atgctctttt cttcaacgag ctcgcgaagt ctttcttcgt ttgtttgctg attaatggcg
    65461 tcgcgccaag ttaattcatc aataatattc attttactga cctccgtgta gtttttttat
    65521 gaaagcagga acctgctagc atgtgtaatt aattatttct tcaggatagg ataggaaata
    65581 aaaaaagtcc cttggcatat aagccaaggg acgaaatctc gcggtaccac ccaatttgta
    65641 tgtctagata tccaacatac ctctcgaaca tttaacgctg tcgcgtggca atcactgcca
    65701 aagactcctg aaatgtaatt cgctttaaag catgtactgg tttgcagcga ccaccagctt
    65761 tctgaaacat tggctttaac aactacttcg tttcgatctt cgtcttgtta ttattaatat
    65821 gtgtctatca tagagcgcaa ctttttcttt gtcaacagaa aaaggatatt ttttttaaat
    65881 tcctcatttt ttcttttttg aatccgctct aattccgaac attttatttt caattattgt
    65941 taaaagaaat aactttttct gtattttttc tgcaatttat cgagaagtca ctttactttg
    66001 cctcttattc tttcttcgtt acaataagga atgggacaag taaaaaaatg aaaaagcaag
    66061 ggacgaggta tatggaaaaa aagcaaaaaa ttattttagg agccacttct gctttaacta
    66121 tcgttatttt aattctaagt ttgttttttg tcatccgatc atctacaaaa aaagaaccaa
    66181 tcattcctga aaaaaaaata acagaaaaag caaaagaacc gacagatgat aagcaacaac
    66241 tagttactca agcaaaaaat ctggctcaaa gctacgatta tgaccaagcg attgcgttat
    66301 tggaaaaaga tagtaagaac ggatctactg aaacacaaca gcttcttcaa acactaaaaa
    66361 aggagaaaga acaactgatc gactggtctg atcctactca gatctctcat gtctttttcc
    66421 acagcttgat cgtggacccg caaaaagcct tccactctca acaggcacaa ggatacaaag
    66481 attatatggt gactgttgaa gaattcaacc gttcgatcga acaactttat caaaatgatt
    66541 ttgttttagt taatttgaat gatttgatcc aaaaagacga acaaggaaat ctttccttta
    66601 acgggcttgc gctacctgaa ggaaaaaaac cattggttct ttcacaagat gatgtcagct
    66661 attatgaata tatggataat tccggttttc ctagccgatt ggtcgtatca aataacaatg
    66721 aaatcaaaaa tgtctataaa gagaaagata aagaagaaat cggtgacttt gacatggttc
    66781 ctctgatcga tgcctttgtc aagaaacatc ctgatttttc ttatcgaggc gcaaaaggta
    66841 ccttggccct gacaggttac aacggagttt taggttatcg aacatcaaaa tctcaatatg
    66901 gagacaatga aaaaacaaaa aaagagatta aagaagctaa aaaagtggcg gaacagttga
    66961 agaaagacgg ctggagcttt gcttcccata catggggtca cttgaatatg actcaagctt
    67021 cactagaaga tgtaaaaaaa gacaatgaat tgtggcagca agaagttgca cctatcctag
    67081 gaaaaacaaa tattctgatt tatccatttg gtgcagacat cagcgactgg cagccttatt
    67141 cagcagaaaa tcaaaaattt gcttacttga agagtcaagg tttcgatatt ttctgtaatg
    67201 tcgatgcttc tacaccagct tggggacaat taggtacgga tttctatcga aatgctcgga
    67261 tcaatatcga tggcattcgt tttcaatctg atttagacgg aaaaaatcct attcttgatc
    67321 cattcatcaa tgtccatgat gtctatgaca aagaagcacg cgaatctgct tgattttacg
    67381 tcatttatga accaaaaaag ccgaactgac attttatcgt cagtttcggc ttttttatgc
    67441 tttatttctt cttcggtgcg attcccttga tcaggacttc tgtccattct gctgtatatg
    67501 gaagcagttt tgcgtatatc tccggcttag aaattccttc taccattgct tgaaaataga
    67561 ggatcaagaa ctcatccgaa tatttcaaat ccacttttcc ttctttccgc cctcgatgga
    67621 aaagatcaag catgatactg aaactttctt gcgtatacgc atccatcgcg tcagaaaatt
    67681 cttttttttc tttttttgta tagtatgtca tcaaatcgat ataaaattgt ttgttcactc
    67741 gattgagata acggattttg ttttcactca tggcaatcag tgtttcttca aatggaagat
    67801 tttccgcaat caacgctttc gcttcttgcc ctaaatcatt cataaatgca aaaaatactt
    67861 cataaatcag cccttccttg ctgccaaaat atttaaaaat cgtcgcttta cttacctgag
    67921 cgttctcagc taccttatcc attgtcactc cagcggttcc tatgtctgtg ttcatcaagt
    67981 caaaagctgc ttgtaaaatc tctttctttt tctcttgtgc tctcttttca aaaccgttca
    68041 tttgtagagc ctcccgtaat tttaaacttt tataatatat atagttcaaa tttattctga
    68101 ggtttattat aactatctat tgagaaagta tcaagctagc aattccttgt ttatgaattc
    68161 attgacagaa atttataaaa agaatattat gtactaaaat aataaaaaaa gttttataaa
    68221 aaggtataaa acctttttat taaactattt aatcttgttt agtatatatt tttagaaaaa
    68281 ggagtggggt ttttatggca gaaatcgtca aagtcacaca tttgaaaaag agctttggtc
    68341 gtttcgaagc tttaaaagat gtctctttca ccgtacattc aggtgaagtc gttggattta
    68401 tcggaccaaa tggttctgga aaatccacga cgattcggac acttttaggg attataaaaa
    68461 aagacggcgg aacggcaacg atttttgggc aagatgtatg ggaagatagt ttatctatcc
    68521 atgaacgtct ttcttatgtt ccaggcgata tctctttgtg gggaaatttg actggaggag
    68581 cgatcatcga tctcttcatg aagcttcatg gaaaagggag tgctcaaaaa aaagatgaac
    68641 tgattcaacg tttctctctt gatcctaaga aaaaagcaaa aaactattca aaaggaaatc
    68701 gccaaaaagt gggcttgatt gctgctttgg ctgttgattc ggatctctat ttatttgatg
    68761 agcctacttc tggtttagat cctttgatgg aaacgatttt ccaagaagaa gttgaaaaat
    68821 tgaaagaaca gggcaaatcc atcctacttt cttctcatat tctcagtgaa gtcgagcgac
    68881 tagcggataa agtcgtgatc atacgcgaag gaacactcga tgaagaagga acactcgatg
    68941 aattgcgtca tttgactcgt tcgaccatca ctatagaaac agaagcagag aatagtcact
    69001 tagcacaatt gaacggtgtc catgactttg tgcaaaaagg tcacctcgct caatttgctg
    69061 ctgataacga agctttcgat gtgattttag ctgaagcgtc caaattaggt gtgaaaaaat
    69121 ttgaatctat tccaccgact cttgaggatt tattcatgag acattatgaa ggatgaggag
    69181 gaagcgaaat gactgataaa ttttcacgct ggtccaccct tttttctcaa aaccttagcc
    69241 gtgactggaa aaagatcctg atatggctag tcggtgtcac tgctttttct ggtggttttg
    69301 tccctgcgtt tgaagaattg acttccggac aaggattagc tggattatac gaaaccttgc
    69361 aaaacccggc aatgattgca atggtcggac caactccagc ttcgaatgct gctgagtata
    69421 ctttaggagc gatgtatgca aatgaaatgt tgcttttttg cagtttgttt gctgctgtga
    69481 tctctgtttt acacgtggtg agccaaacga gaaaaaaaga agaacttggt ctgattgaac
    69541 ttattcgttc ctttcgagtc ggacgtcaag caaactcttt agctgtcatc gctgaaagta
    69601 ttctgatcaa tttgctttta gcaatatcga tcagttgtac gatgattttt ttccaagcgg
    69661 attcgatcac tgcagaaggt gcttggcttt ttgggctatc tgtaggtagt atggggattt
    69721 tggggagtgc cgttgcactg tttgctgcac aactgatgcc aagttcagcc agttcgaatg
    69781 gtctgtcttt agcgttttta ggtggacttt accttctacg agcaataaca gatgtagctg
    69841 attcctccct ttcgatgtgg aatcctttag gctggtctta tttgacctat ccatttacaa
    69901 ctaacaactg gattcctttg ctttatttgt ttttgttcag tctaatcttg ataatcagtt
    69961 catttgtttt agaggaacat cgagatttga acaccggcta tatccccgaa cgtgaaggaa
    70021 aaccgtatgc taaacgttct cttttatcct tgcgtggttt attattctat ctaaataaag
    70081 ggatgacaat cagttggctt atcacttttg gtttgatggg ggcggcatac ggctctatct
    70141 acgggaatat gcaacagttt ttagaaagta acgacttaat gaaacagatg tttatccaat
    70201 ctggcgtctc aattgaaaaa aactttacaa gcacgatcat ggtcgtcttg atttgtctag
    70261 ctgctatttt accaattgct agcatcaatc gtttatttac agaagaaacc cacggacgta
    70321 tgaatcagct gttcgcaaca aaaatttcta ggaaccaact ttattggacc aatatgttac
    70381 tagctattct atttgctata ttggcaatcc tgattagttc tggtgcacta gggctttctg
    70441 ctttggcttc gatgaaggat gcgaaagaca tggatctatt gatgtttctt aaagccgggt
    70501 tcaatttcct gcctgccgtt ttagtgttta tcggaattag tggctttcta ttcggatggc
    70561 ttcctcgaat cggtaaactt gcttatatct acttagctta ctcctttgca ctcaattact
    70621 ttggcggaat tttggattta ccagaatggt tttccaaaac agctgtccct agctgggttc
    70681 cacggatgcc aaacgattct tttgatcttt ccgtgttcct tacgttatca tgtatcagcc
    70741 ttgcactgtt cgtccttggt tctattggtt ataggcgaag agacttacta gaaggataat
    70801 aaaaaagcat gtacaatttc atgctagcct ccaaatctgg gtcaaaaatc caacatttgg
    70861 aggtcatttt tttatttaca agtcttctaa ctgctcttta tcaatgatcc agacttctcg
    70921 attctttctt tttacataac cattctcctc taataattta aattttctag ataaagtttc
    70981 gggggtcgta ccgataaatg cagcaagttc tttcattttc attggcagga aaaagtgatc
    71041 cttccctgtc gctttagcta agtcaagcag atagacagcg actcgttctt ctactttttc
    71101 catcatcaaa aaagttgtct gctgctgtac ttttgttaat ttctcaacgt tgattgctaa
    71161 aagtttcaga ctaagggcgg gataatgcag taagagttcc gagaaatctt tttgtctcaa
    71221 tatgcaaatt tccgtttttt ctagtgcttc gccaaataaa gactcatttg gaacgcctag
    71281 caactggctc tctccctcat atccgcccgg ctctattact cgtaaaagct gttcctttcc
    71341 gctagcagat aattgataca ctttcatact gccggaggcc acgatcacta attgaggttc
    71401 tccattcggc gcaagaatct gttctccttt ttccacatag tgatgtttga caagtgcgtg
    71461 tactttttct tgatcttgct gtactaagtg attgaacaaa ggaacaaatg aaacacataa
    71521 atgatcatga ctcataatct ctcctccttc taaacagcta tttctaataa agaaacataa
    71581 cttcccttat tccaactgat aattttcttt tatcatagca taaacgtcaa gcgaaccaga
    71641 taccagcaaa tagagtggat ttctttttgt cccttgcttt attttccttc ttttgagacc
    71701 ttaagtaatt gattcctatc aattttttaa atatttactt tttgaataat caaaaacaaa
    71761 ccttcactcg caagccgaga gtaaggtttg tttttcgcat tgcttatttc gtgttgtcta
    71821 ttgaaatttt tccgcaccta gcttttgata tagtggtgct agttcttgta aggtttcagc
    71881 ggttatttgc tcaacgtgtt cgatttcttg cggatagaag aatagtttac ccatttgaaa
    71941 ggttcggtct ctcatcgctt ttttcaactc ttcttgtttc tttgtatcgg acaaatagtc
    72001 agacaaagct aagtggtcgt caagttcatg ttctggttgc ggccatatgt aataatcctt
    72061 gatatcgact gttttgctcc actctttcag tatcgcaagc aactggttat acgctgcaat
    72121 gctaccatat cgttcttcgc ttttataatg ttggtacatc aaatagattt ggtattgttt
    72181 ttgattcaac aaaactgcta gacaggcatt ctcgtcttga cgagattcgc ttcggtacgc
    72241 gctccaaaaa tgactgcgta aattccagcc attcgtccag ctttcgattt taggtttgct
    72301 catgccgtac atatcaggca aaagtgcagc tgtctggagc tgaatctctt tccatttttg
    72361 ccagtgttct ttatattctt tcttgatttg ttcaatctta tctgttggat ggctctcttt
    72421 gagctgtttg aatgcgtaga ttggtcgatc aaacaactga taatctgatt ttccaagttc
    72481 cattgtttcg cctctttccg ttatcttttg tattctacct gaattttgcg atatggacaa
    72541 atagaggttg tgaaaaagct gttctgcatc aagtcataag aacagccaaa caaaaaactg
    72601 cgatgagcat caccgcagtt ttattgaact taaggttgat tgatcacatc taaaagcgtt
    72661 gaaaataaaa tggcactaga agcagctcct gggtcgatat gtccgattgc acgctctcct
    72721 agataggaag ctcgtccttt tttagctacc aagactttgg tgtgttcttt tgcctggtca
    72781 atgatttctt ttgttaaatt ccctgccttc aatgcctctg tgactggcag ccaaacatct
    72841 aacatcgttt tatcgtcagc ttctgccttt cctcggcttt gaatacccgc tgttccctgc
    72901 tcgatcactt cgcctaattt ttcttgagaa tcaatagaat cgacctcttt tgtcgctttc
    72961 atcatgttca tgaatgcaga tccgtataac ggaccagaag ccccaccgac tttcgatatc
    73021 atcgccatag agaatacttt gaatgtatcg ctgattgttt caggatgatc ggcttgaaaa
    73081 gcttcttcat aagctgaaac ccctcttccc atgttatttc catggtctcc atcgccaatc
    73141 ggggtatcta gatcactgag atattgtttg ttctgattga ttgcctctgc aaattgcgtg
    73201 agccattctt ggatttcttg aacggttagt ttcatattat caccctttta tcttgagatt
    73261 ttttaccatg aaatcgtctg tacattgctt tctaaagaat ctttccattg tgtctccgtc
    73321 aagtcgatca gtgttagaga aagaccttgc atatctagtg aggtcataaa attaccgact
    73381 tttcggaaaa ctacattgac gcctctttct tccaacagag ctaaaacatc attcatgaac
    73441 acgaactgtt ccatcaaagg cgtcccgccc attccgttga ctagtacacc tgcttctttt
    73501 ggtaaattcg agtaatcatc taaaatctta gtaacaagtt cctttgccag tactttagaa
    73561 ggctgcatct tttctcgacg atagcctggc tcaccgtgga taccaacacc atactcgatc
    73621 tcatcttctc ctagttcgaa tcctggtttc cctacttctg gtacagttgc tgctcgaagc
    73681 gctagaccga tcgtcttagt tgcctgtacg accttttctc ccagttcttt caactcagct
    73741 agggaagcac cgtttcttgc tgcatcgccc acgattttgt gtacaaggac agtacctgca
    73801 actccgcgtt ttccagcagt atacgtacta ttttcaacgg cgatatcatc atctacgatc
    73861 acactttcta cttcaatatc gtccatagca gctaattcct ttgccatatc gaagttcaat
    73921 gcatcccctg tataattctt aacgatcagc aaaactcctt ttccactatc ggcttcctta
    73981 atagccgtct gaatctgatc tggagttgga gaagtaaaca catcaccaag caccgctgca
    74041 cttaacatcc cttcccctac aaacccggca tgggatggtt catgtccgct tcctccacca
    74101 gaaaccaaac caacttgttc cgctttctga ttcttggcta caacacggga agattctaca
    74161 cgatgaacaa gttctggata gctttttact aatccttcca gcatttcttc gacaatattg
    74221 cttggatcat tcatgatttt tttcaattta ttcccatcct ttctttccgg cattttgtgc
    74281 ttctgttaag atttgctgag tatcatctgt tataccggca gtgatggctg ctgcaaaagc
    74341 tccttccact aaaggcgcat ccaccagatg ataacgttgc tgctgctctt cttccaacat
    74401 gtcttttgcc agttccgagt tcaataccgc gctaccgata tccgcaaaaa caaaataact
    74461 agctgcatcg cttgattcat tgactgcttc tacgattttc atcgggtctg atccgatctc
    74521 gccatttatt ccgccgagag aaaaaatttg cacctcttcg gatttttgca tctgctcaat
    74581 catttcttta ataccatctg ttactttttg actatgagaa ataagcaaaa tacttttttt
    74641 cacaagaatc ttcctttctt ttacatagtt gctaacgatt ggtttcgctt tcattaatga
    74701 acaattcaag tatataataa atttctaatt ttgggaaaat atgtgtagtg cttcttgaag
    74761 tttgttatac tttaattaaa agagaggagt gatcgaatga ttacaacaac aacgaacagt
    74821 gtagagggaa aagccgtagt agcttataaa gggatcgttt ttggtgaggt cattactggg
    74881 atccatgcat ttaaagactt ggaggcgggg ttgcgaaata tctttggcgg ccgctcaaaa
    74941 agctatgaaa acgaactaat gggtgcaaga gaagaagcac ttgccgaaat ggccgaacgt
    75001 gcaaaagcat taggagctga tgcgatcatt ggcgtaaaaa tggactatga agtattaggc
    75061 agcgacaatg gcatgctgat ggtcacatgt agtggaacag ctgtctccac gagataagta
    75121 ggggacatct gttttaataa ctaaagagag atgggacatg tagtggcact caagaattag
    75181 atttttcagt ctaacttcga ggtactctac cttcccatcc tctctttttt atttcttttt
    75241 gcggatgatt ccgtaagctg ctgcgactaa cacacccgcc cctgctaagg aataactgac
    75301 agaagctgtt ttttcatttg tttttggcaa agtctgactt gttgatttgg atggctctgt
    75361 cgtttgctga actgtttctg tcgtgcttcc agaggtcact gatttttctc ctgccgaatg
    75421 caaaatatct tttattcgtt ggaaactagc tgctaagtca gctttttttg cttcaaaatc
    75481 attagcaact gtttgtgctt cgctgatctt tccgtggatt gcttgactgg ccgctgtgat
    75541 atccgcttga gtttgactta gctttccaga agctgtttga gcaacctgat ttaattgctg
    75601 attgaattct tttgcttgtt ggatcttccc gtcaagatct gtttggacag cttccgcttt
    75661 tgctttcgct tcggcaagct ttttctcaag ttgtgcacgg tcatttccca ctttattttt
    75721 aagatcagct aaatcttgat cgattgctgc ttggtcttct ttcaatttgt tttttgcagc
    75781 ttctaatgct tcttcgagtt cttttctttt attttccaag tcttgcaaat gatcgatttg
    75841 gtcagaagag gtagaactat ttattgatgt atcttctgaa gatgaaatcg tttctcctga
    75901 attatctgtc ggtacattgg aagtcatttc tgtttccgag gcaccgtttt cagcaccaga
    75961 agagcttatg gttgttgaag gttctgtttg agcaggttca gaagtttccg caaaagctgt
    76021 ctgtcccaat aagaaaatac tggaaacagc aattggccag attaacggct tcattctttt
    76081 tttcatcact tttcccatcc ttactacttt ttaactaatt tcttattata agcaaaaatg
    76141 tttggaagaa ccataaacac aacaggctgt ttgtctaaaa aacggtgcat cttttatttt
    76201 tttgtacgtt ccgggctttt ccatgtcccg cttccataac ctaaaatcgt tttgactgct
    76261 ggaatgaaag tcgtcacgat cgttatcgcg ttcactatcc agaacaaaag catatatagt
    76321 ggtgcgaaaa gaaggtattt caattttctt cgtcgatcat ctacaatcag cgaagctagc
    76381 aactggaaaa atcctgcgac catttcaaag cagatgaaca caaaactgaa tgtaaaagta
    76441 atataaatct gttcgtagtt tccttgatat acataatgcc cgattaatcc agcaaaaaga
    76501 actacggaaa tacaaaagaa tattgaccag acaatactca atgtttgatc aatgaagatg
    76561 atcgttcttc caatatgttt aaaaggatgg agcatcactt ttttgaaatt cgtcagccag
    76621 acttctgttc caccttttgc ccaacgtttt ctgtgtcgat atagcatctt caacgtcaca
    76681 ggtacttcca tgaaaaagat aatctcagga gcaaaaacag ataaccagtc atttaactga
    76741 tgatcccaag caatactgat gtcttctgtc gctcgatctt gtctgaatcc gcccacatcg
    76801 atcaaggctt cttttcgata catcgtattt gctccactgt acgcataaag accaccgaaa
    76861 acagctgact gtgttcgttt aatgatgccc acgatacttg agaattcaac cgtttgagat
    76921 tttgcaatca atttggtacg attttggaca tccatatttg cagtgaccgc agcaatatgt
    76981 cttgcaccag ggcgaatgaa ataattcaca tacctaatca gtgcatctgg ctccggtacc
    77041 gtgtctgcat cattgcttaa aatcaatttc ccttttgcaa aggcaagtcc gatattaaac
    77101 gcgtgggctt ttcctttatt tttttcgatc cgaaccacac gaagattagc gtattttttc
    77161 atcagtctag ctaatatttc tggtgtttgg tccgttgaac catcgtctgt cactaatacc
    77221 tcatagttgt gataattcaa tttcgtcatc aaatactcga ttgtatattc gatcacaatt
    77281 tcttcattat gggctggcac catgatcgtg atgaacggtt cgacactcaa gggaacatct
    77341 acccattctt tttgcttatg tttgtataaa aacacataac accagacacc aataaaccat
    77401 acaaatccgc ctaaaatcgg ataagaaacg agaaaaaaat acataataga caaacaagta
    77461 tctaagaata aattacctgt atgggtgatt gagatcattt cagttccacc ccattttctt
    77521 tatacaaatc tgcaatgaat gtcgtatcta gatttttctc ttcggagaca gaataaaaac
    77581 ggaccgtttc tctctcttct tttgttccaa aacgttccgt atacacttct tcaagtaatt
    77641 cttgtctttt tttcaatttt tcatcttcat attcaaaaga tttatttact tttttgtata
    77701 gatttcgatt gttccaccta gtcaatacaa atgaggtaat caggaaactg aaaaaaatca
    77761 atacaaaaaa gccgattaag aaatacagca ttttcttttc tgataaaaaa gcgtacaagg
    77821 aaaaatcctt ggctctttct ggtctcgtta atgggaaaaa gacccatata aaaggaagaa
    77881 caacgatcat ccatcctaaa agagccacta acgtttgcca aatctttaac cagtaattac
    77941 cttttgaaaa atacttatct ttcaccaaaa ttgatgcaac ttcttctctt gttacttttt
    78001 tcatatcctc acctcacgtt tttttgttac gacgtaggag tttaccatac atttcatttc
    78061 ttttcacata aagtgttcct aaatttttcc taagaaaaag aacaaaacat ttctcatcag
    78121 caaatgaaaa atattttgtt ctttttatca gttgttcttt ttatttttta tctcttaatt
    78181 atgttgctct ttccaatacg acaatgcttt tcattcctct agatatcgcc gtgtacattt
    78241 gtctgcgtct tctttgctca tctccatcgt tttcaaatgg atataagatt acatgatcaa
    78301 attccagtcc ttttgctaga ctcaaaggaa tgatttggca gttttctaat ccatatgaat
    78361 tttttttaat cgattcttgt agcgtttggg tttcctcttc tgtttgggtg ataactgccg
    78421 ctttttctcc ttttagagaa accaaaatct cagctagtat tttcaacaat tcttcagagg
    78481 atcgaaaaga gcggtattcg ggttcttttc cttgcggtcg gatcgatacg atgtcgatct
    78541 tctcttgatc cacagcatag gttttgaaaa gctctgtgat tgctccgcta gaacggtaac
    78601 tatttctaag atcataccga tggatcggca gatggtagtc gtcgaaacaa cgcataatat
    78661 cagcaaaagt agtggaagaa ttaaagattg cctgattctc gtcacctact aaagtaaagt
    78721 gagtttttgg aaataattcg atcaatagac ctaattgtgc cagggtataa tcttgtactt
    78781 catcaatcaa tagatagcga aatgctggta catttacctt ttcaacaagt aaatgacgaa
    78841 tagctaatat aatgactgct tcatcaacag tacgtgtggg ttgccaagca taagctgagc
    78901 catatcgttt ttcataaatt ctttcaaaca actgatgctc atccacccat gccatttctt
    78961 cgatttgtct ggttattttt cgatattttt tttgtaaaag tttccttgca taagctacaa
    79021 tactttgttc cgaatcatca gaaatcaatt taccgaataa ttccaactgc ctatcttctg
    79081 tcaacgagag tacctgattc tgcacagcag gactttttgc ttgtttcaaa agatgattct
    79141 tccattcgct catcagtgcc tttttcgttg cttgaagcct atcgatcaat ttaggatgag
    79201 caggaacttt ctcatatatt ttttcgatcg tttttttaga aaggactgtt tttccatttt
    79261 tagtaagtcc acggataaaa ttcggatgat ctaaaaacaa aggatctgat tgttttagat
    79321 tatcgataaa ctttttgcta cgcaaacgtt ctgtctgctc cgatacattt tctcccgtga
    79381 tacgtttgaa ataagcctct tcaccttcta tttcctctgc tgaaagctgt gaaaccagct
    79441 gtatgatggt tagattcagt ggatttcttt cacctaatga tggtaggaca ttcgaaatat
    79501 agtcgataaa ccgatgatta ggtgatagaa tcagcaagtc atcggatgtc atcgtatctc
    79561 gatataaata gagcagatac gcaatacgct gcatgatagc agaggtttta ccacttcctg
    79621 ctacgccatt taccaagata ttttgacttt tcacatcccg aatgattgtg ttttgttccg
    79681 attggatcgt agcagtgata gccttcattt cattggtctc atcttggcct aagacttcta
    79741 ataatacgtc atcttgaata gctacagacg tatcaaaaaa cttgaccaaa cgatctcttt
    79801 ccaaaagaaa ttgtcgtctt tctttaataa ccgtatcgat tttattttga cgaaccgtat
    79861 aagaagatgg accaatcatg ttattgtaaa aaagttcggc aattggtgaa cgccaatcat
    79921 aaacaagatt ttcatctgca tcatctgtga aatttgctgt accgatataa aaggattctt
    79981 ttggctcatt atccagaaag tctacaacga cttttccaaa gtagggactt ttcaataaac
    80041 gttcgatctt tgctagctga ttttctgcgt ttttctgttt gatattcatc tgatcgattt
    80101 ctctattttt catttcaatc atcgaaaaag tatccaggtt atctaagtaa ctgtcaaaat
    80161 tcaatcgaag ctcgccagcc atttctttca acgactggtt tccttctatt tttgccgtat
    80221 ccatcgattc ccgcagttcg ttttttttat caattagctt ttgatacacg ttcttcagat
    80281 atgcttcttc taactgtttt tgtgtgttga ccatacacat tctcctcttt ttttaaagtg
    80341 gtggaaccga ttagtttacc tcttttaaga gtcgaatgca agctttttaa cgagtatcat
    80401 ttgttaggat atatcagttc ttcaggtcgg acagtttgat ataaagaaaa tgcaccatca
    80461 aggtttttta cgtggtagcc agactgcttc aagattcttt ccgctagata gctacgtaat
    80521 ccgctatgac agctgacgat atattcttgt tggctgtcta attcatttaa tcggtcccga
    80581 agttcattca aagggatatg tttggcttcc ttgaatttgc ccttttccaa ttcttctgct
    80641 gttcgcacat ctaataaaat ttttcctttt gctagttctg tcggcaattc atgccattgt
    80701 acggtttcac taagcccttc tgcaatgttc attgctgcat atcctagcat gtttactgga
    80761 tctttggctg agccaaatgg cggtgcatac gtcaattcta attccggtaa atcgaagatc
    80821 gtcaaatgcc ctttgattgc tgttgctaaa atatcgatcc gtttatccac accttttgcc
    80881 ccaacacctt gtgcaccata aatctcgcca gtctctggat ggaagatcaa cttcagtaaa
    80941 atatctgttg cttctggata atagcttgca tgatcttttc ctgatacatg aatgacttca
    81001 aaagacagtt cgttttcttt ggctgttctt tcacttaaac cggtggatgc ggcagtcatt
    81061 ccaaacgttc gtataattgc tgttccaata ccgccttgat ttcttcgaga aattccggaa
    81121 atcgtgtccg caacttgtct accttgacga ttggctggtg aagcaagaga aataagtgca
    81181 tcttttccag tgatttgctg ttttacaacg atagcatccc ccaccgcata aatatcagga
    81241 atattcgttt gataacgttc gtctactagg atacccccgc gtatgcctaa ttcgattcca
    81301 gcggtcactg ctagctggtt atcaggacga acaccaatgg ataaaataac taaatcagca
    81361 gggatggtac gcccatcatc cagtcgcaat cgtttcccgt ggtcttcaaa tccagcgaca
    81421 gcatgagaag taatcacttc tactccttga tgagacaatt ctttttctat aaaagctgcc
    81481 atttcttcat ccagtgttgg aagaatatgt ggtgcttgtt cgatcaccat gacttctaaa
    81541 cctcttcttt ttaggttttc tgccatttcc aatccgatga atcctgcacc aacgatcacg
    81601 gcacgctttg gctgtttttc taatgcatgc atcactttat cgatatctgg tacatttcta
    81661 atagaaaaaa cattgtcggc ttctgttatc cctggaatcg atggaacaac tggttttgca
    81721 ccaggagata aaaccaatgc atcgtactgt tcaatgtgtt tttgaccctc atgtacgact
    81781 tctaccgttt tgttttcggg aaagatggct gtcacttcat gatttggacg cacatctaaa
    81841 caaaaacgag cggataatga ttctggcgtt tggacaagaa gattttcccg ttcactgatt
    81901 tctcccgaaa gataataagg caagccgcaa tttgcaaaag aaacatacgg tcctttttca
    81961 aaaacaacga tttctgcatc ttccattaat cggcgaagcc gtgtagcagc agacattcca
    82021 cctgctacac ctccgacaat aacgattttc atcttatttc cctcctactg ttcgatcaaa
    82081 ccattgattc atgccaccac gtacattcac tacatcataa ccagatttct ttaattcttt
    82141 agctgcttgt ttactcctca tccctgattg acaaatcaca tagacggtct tttctttgtc
    82201 tccatcatat ctgtttatac tttgtaatgg aacattttta gctcctttta tatgcccgcc
    82261 ccggtattct gcaggtgttc taacatcaag taacgctgga ttttccaaaa gcttttcctt
    82321 taattctggg actgttatcg attttattga ttgaaatagc aaattcattt tctgcacctc
    82381 atttacattt ttataaatac ctcatggggt atattaaaca ggagctttat taatatgtca
    82441 accaaaatga ctcttcattt ttttcactac tttttatatt tgcataaaat accgataagg
    82501 ggtattatct aattataaaa atagaggaga atgtgttatg gagattgata ataaaaatat
    82561 cctgaaccgt ttgaaacgta cagagggaca aattcgtggt atccaaaaaa tgatcgaaga
    82621 cgaaaaagaa tgtatggatg tcatcactca attaagcgct gttcgttcta gtattgatcg
    82681 cgtaatgggc atgatcgttg cagataatct gaaaaattgc tttgagaaac ctgatagtaa
    82741 tccagaagaa caagcggcta aactagaaca agcgatcaag atgattatta aaaagtaaag
    82801 gaatgatttc aatgaaagtc gttttccata ttgatgaatt agaaaaatgg tcagaaacag
    82861 ggaaaaacgt aaaaaacctg ataaaagctt ctccagaaac gacgattgtc gtatctgtaa
    82921 atggcatcgc gattaccggt tatctagact ctgccaatgc agaattctta gatttgcaag
    82981 gagtcgtttt tcacgcttgc gccaatgcta tgcgtgctaa tcatatttca gaaagttctt
    83041 tacctgaaca agtaatcgtt gtaccagcag gtgtccttga tttagttgaa ctgcaatccc
    83101 aaggttatgc ttatatcaag ccttagtcag tagaggttgc gacagaagtg atcagcttca
    83161 agaaatttcg gcttattttt cgaagaagct acttctggaa aaccgtgaat caaaggttgt
    83221 gaaaacgctg tcctgcatca agtaataaga acagccaaac aaaaatagct tctcatattt
    83281 ttcgtttggt tgggcttatt accgcagatg caagcttttg aacaccgttt aaggaagagg
    83341 ttgtgaaatc agcggtttga cctaagtatt agagaaaaaa acgggaaaat agctcctcat
    83401 attttgccgt tttttgagct aataccgaag gtcagctgat tgaacaccgt ttaaggaaga
    83461 gattgtgaaa aagtcgctta gtttcgagta ttaagaaaaa ttttgtgaaa atggatttct
    83521 acatttttgc ataaatttgg cttaataccg agaaactggc ttttgaatac cgtttaagga
    83581 agaggttgta aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagctg
    83641 ctcatatttt gccgtttttt gagctaatac cgaaggtcag ctgattgaac accgtttacc
    83701 aagaggttgt gagcctacca tttaactccg aatcacaaga aataatttca aaaacaactt
    83761 ctcctgtttt tggttcggtt ggcttattat cgagaagtag ctactgggag tctatttatc
    83821 aaaaaaagga atgcgacata ggtcacaccc cttttttatt ttctttgaaa catctttcgg
    83881 tactcgacag catacaagac aaaagattgt aaaagaccgt aagtgatgac ggcaaaaatg
    83941 actctcaccc acagcgttgg taattctggg aaaagcagca aaaggatcat gccaacatag
    84001 atgacagcag tcgctacttt gccataccac ttcgctccac ttaatttgat atttttagat
    84061 agcccgatta atccagctac aaacataaag ccttctttta tcaagaatag accaaacaac
    84121 agccaaagcc acggtcgata ccatgccata gacaaaatca gaaaaagttg tgtcaattta
    84181 tctgcaaacg gatcaagcac cttccctaag tctgttacct gattatatct ccgagcaatg
    84241 accccgtcta gataatcaga caaacctgag acaacaatga ccgctcctgc tatataaaat
    84301 gactgtctca gcacaaaata aagataaatc ggcagcaaaa aaatacggaa tatcgataaa
    84361 agattcggaa tcgtttgtat ttctttacgc cagtctgtgc ttaatttcat tttatcgccc
    84421 tacctcctca gcactctttt ctttttattt tagcttacac ggggaataaa accaatgatt
    84481 tcactgtttt tatttttctt tacagacact gatattatga gctaatttga gataatcact
    84541 tgctgttttc atcgtttact cttctttctt cctgtcgttt gcgcatttct tttactagta
    84601 ctttatgagc tttttttgat cctcgctcta ggtcacgctg ccgtttacgt gttttataat
    84661 cgataaacag actgtctaaa tcgtaacctg tcgggtacag atcttctgct gaacgcacca
    84721 gacgaacacg ctgacgaggc acgtggatta tttttttgtc taaatataca tcaatcgtat
    84781 cttcacctat atcttcataa actaacgctt ctttttggta ttcattgaca aatatccgat
    84841 caccttttgc aaagagctga cgttcttttt tattctcctt cctatttgta actgctgtct
    84901 taggaagaaa ttcttttttc tgtgtccgat aggctttttc cgccaagtaa cgctctgctt
    84961 gatggatcaa tttcatcgac atatccattt tatgagcaat ccacaaagct tggctttctc
    85021 ctgtttcttc caacccgcaa ctgatattta ggacgaagtg cttcccgatc gaaagccata
    85081 gcagccggca caaaatcttc atgatctccg gcgaatttct tgatttctcc ataatgggtc
    85141 gtggcaatga tcaatgcccc ttgctcatac atagattcca tgattgcgat cgctagtgca
    85201 gccccttcat ttggctctgt tccactgcca atctcatcta aaagtaccaa cgtattcctt
    85261 tttatctttt tcaaaatagc agcgatgttt tgcatatgac cagaaaatgt actcaacgca
    85321 ttttctaaat tttggtggtc accgacatcg acgaaaatct catcaaagac agcaagctct
    85381 gtcccttctt ttgccggaac ttgcataccg aacatcgcca tcaaagtcaa taaaccgact
    85441 gtcttcaaca cgactgtttt gcctccggca tttgctccgg tgataatcaa gcctcgatag
    85501 tctttaccga tttcaacatc caatggtacc gcatgctcag gtaaaaatgg atgtctgcct
    85561 tgcttgataa tgatatgttc cgatttattg attctaggtg tgcttccatt gatttctcgg
    85621 ctaaattttg cccgagcaaa gatgatatct aacaccgtga tcgtttcgat caataaatcg
    85681 atcacttctt cgttttctgc gatagcacca gtcaatgccg ccaggacttg atattcttca
    85741 ctgatttctt cagcttttaa caactgatag tgttcattca atttagaaat cacagttggt
    85801 tcaataaaaa ccgtcgttct tttatttgat tcatcgataa tcgttccatc tattttattt
    85861 ttatagctgg ctttgatagg aatcgtatag tattcgcctt tttgaacaat cattgcttct
    85921 tggatcattt ctttgttttt cggatgacgc aagaatttca gtaattttga ctggatttct
    85981 ttttcgatta gttgtaattg tttgcgtact ttacgcaaat tacgtgacgc gtcgtcactg
    86041 actttattat tttttatttt ctggtcaatc aactcttcta catttatcaa atcaggaaga
    86101 tgtttgctat aagcaaacaa caagggtgtc tggtattgat tcttatcaaa aaactttgtg
    86161 atcatccgac tgcttctaag aaaatccgca tattcgatca aatcggttgg ctgcagaatc
    86221 aacccttttt tgacttgttc tgtcagtgca tcgatcctcg gcaaccccat aaatggaaca
    86281 tgctgactgc tttctaagat caagcgtgct tctcttgttt cttcttgacg atccaagaca
    86341 gtttgtaggt ttgtcgagac cgtcatatcg ctgattcgtt ttttgctata gtttccaatt
    86401 gctcttgctt ggatttcctt tttgatccga tcaaattgta attgactaat catttcgttg
    86461 tccatattct ctccttttct tgaagagata cctgtcccaa aataaataag ggcctagaga
    86521 taaataaaag gatagaacac agcttaaaaa agtcatgtcc tatccttatt agaatacaaa
    86581 gatattgttt tcctgacagg taccgtttca taagcacacc aaataaactt tgtttattgg
    86641 ctattcgact tactgattag ataccagcta cactcacaaa acatacccca ttcttctagg
    86701 tcttatttat tttccactta actatagcaa gacacatttt ggttgtcaaa ctttagtatg
    86761 ttttatagat ttacaccatt aatgaataga cacctaccgc gataattgct ccgatcattg
    86821 gacctgcgat tggtacccat gaatatgccc aatctgaagt tcctttatta gctattggca
    86881 ataccgcatg tgctaatcga ggaccaaagt cccgagcagg gttgattgca tatcctgttg
    86941 gccctcctaa tgaaagaccg atggctaaga tcaatccacc tacagcgaat acgttcgttc
    87001 caggtgcaaa ttcgttttgt ccaaaagcta gcaacccaag aactaataca aatgtaccaa
    87061 ttaattctgt gatcacattt gctggataat tccgtatagc aggacctgtt gcaaacgttc
    87121 ctaaaatcgc gctttcatct ttcgttgcat tccaatgtgg caaataagaa agccaaacaa
    87181 gaatggcccc tgcaaaagct cctaaaactt gcgcaatgat gaaaggaacg acaagattcc
    87241 aactaattgc ccctgtcatc gccatagcta gagagactgc aggattcaaa tgagctgggc
    87301 ccatgaatcc agaaatatag acagccattg ttacagcgag tccccaacca aatgcgatga
    87361 caatccagcc agaagcctgt gctttacttt tgtttaaatt cacagccgca cacacaccat
    87421 ctccaagcaa aactaggatc agtgtcccaa taaactcccc catgatttga gtcatatcac
    87481 tgttcattta tttctccccc tttagttccc gcagatctga ttctgcaatc aatgcttcta
    87541 aacgtttagt ctgttgcgcc ttctcctctt ctgtccattc aaaatatcca gcaattgcat
    87601 cgatcacagg ttgcttgatc tcatcaagct gatctcgttc aaacaacaga tgatttgtac
    87661 gacgaatgag ataatcgcct ggggccaaaa ccatttcttc ttctaaacca taacgtaacc
    87721 gagctgactc agcgagactc aaaccaggat aaggtgccat ttcttttgct aattcaaaga
    87781 tacgtcgggc attagtcccg taaaaatcag cgatataagt agcatcttct tcctctaaac
    87841 cggctgctac tccttctttt gctaattctg tcactgtttc ttctaattta gttggatcga
    87901 agtttccacc tgaaatctga tattttttag agtcgatttc tttcgtctct attccgtatt
    87961 cttcttttaa taattggcgt atcaatcgca aagctccttc tgccatctta cggtaatcgg
    88021 tgattttccc accagataaa gtcagcaaac catctggttc tctttctaaa gaactacctc
    88081 tggaaatcgt agaaggtgct ttttcatcac ggctgttttc caaatggttc aacacgtctt
    88141 ctacttcagc acgagaaact ttgttttcct tatattcact tactgtatcg acaactttat
    88201 tgaagctctt gtctgaaatc gatccattat ctccaccatt gtaatcagaa ccagaattac
    88261 caatcaacag tggacgaagt cctgcccagc ttgcttcgat atcattcaat gtgatatttg
    88321 cttctggata gcgatgattg atcacatcca atagataatc tacatcttct tgtgtgactt
    88381 tcggatccgt aaaatctcct tggtaatccg tatctgtcgt accaaagtaa gtcttgtttt
    88441 ctcttggaat agcaaaaacc atccgcccat cttgctttcc tgtatcgaag tatgtgggtt
    88501 gcggtacagg cagttttttc gcatctacaa ctaaatggat ccctttagtt ggacgcattt
    88561 taggagagac tggacgcgta aaattcaagt ttcgtacttt atctacccaa ggaccactcg
    88621 tattgatcac taattttgct ttgatttcga tcacttcatc tgtcagcagg tcacgagctt
    88681 tgacgccaac gatttgatcg ccatcatata aaaagccaac cgctttcatt ttacttacta
    88741 gataagcccc atcttcggca gcctttttga tattatcaat cactaaacgg gcatcattgt
    88801 tgcggaaatc tagatagaca cccgcgcctt ttagcccttc ttttttcaaa aacggttctc
    88861 tttccaatac ttcttctggt gtcagcgtat aattctcata tttggttcct gtcacatttg
    88921 ccagtttgtc ataaaggtcc attgctactt tgaccgagaa catattgaag gttgttgctc
    88981 cttcgccctc atagattggc aaaagcattg gatctggttt tgggatgtgt ggggcaatac
    89041 tttgtacgac tgcacgttca ccaactgtgt cagctactac ttccacatca aatgtcttca
    89101 gataacgaat accgccatga acaagtttgg tcgagcgaga ggaagtccct tctgcaaaat
    89161 cctgcatttc gatcaatcct gttttgattc ctgatgctgc tgactggact gccacaccgg
    89221 caccagtgat tccgccaccg atgatcaaca gatccaattc ttcttgctgc attttttgaa
    89281 tgctatcttg tcttgtcttg tttgaaaaca tatggatttc ctccttattc aaatgcttgg
    89341 gtagctttta ctgctttttt ccaaccgttg taaagttttt ctcggcgctc ttcctccatt
    89401 tgaacttcaa atagcttgcc agcttcataa aattcgcgga tctcgtctgt atctttccaa
    89461 taaccgacag ctaatcctgc taaaaatgct gcccctagcg ccgttgtttc caagttttct
    89521 gctcgttgga tcggtacatt caagatatct gtttggaatt gcatcagata ttcattgttt
    89581 gctgcaccgc catctacttt caatacagga atcttgattc cagtgtcatc ttgcatcgta
    89641 tcgatgatat ctctcacttg ataagcaatc gactgtaaag tagctttaat gatatcttct
    89701 tttgtcgtac cacgtgtcaa gccaaacata gcccctcgtg ctgcctgatc ccaataagga
    89761 gcacctagcc caacgaatgc aggaacaaca taaacctcat cttcgcttgt agagcgtttc
    89821 gctgcgtctt ctgaatcgct agctttttgc aacatttgaa gtccatctct cagccattga
    89881 atcgaagaac cagccacaaa aatacttcct tctaaagcat agtaaacctt tccatttatg
    89941 ccgtaaccaa ttgtcgtcaa taaattattt ttggataatt gcggtttttc accggtattc
    90001 atgacaataa atgaacctgt accataagta ttcttgacca tgcctggttc gaatgccatt
    90061 tgtccgaata atgcggcttg ctggtctcct gccatccctg aaattggtgc ttcgcttcca
    90121 taaaaatgat aaccttgcgt ataaccataa acttctgagt tagaagtgac ttttggtaac
    90181 atcactcgag gaatatttag taaatctaaa atctcctgat cccaatctag ctgatggata
    90241 ttgaacaaca tcgtccgact ggcattcgag taatcagtaa catgtgcttg tccatcggtc
    90301 agtttccata ctaaccaaga atcgatcgtt ccaaacatca attcgccttt ttcagctcgt
    90361 tcttgcgcgc cttctacatg atcaagaatc cagcgtatct tcgttgctga gaaataggca
    90421 tcgatcacta accctgtttt ttcgtggaaa aattcttgat agccttcatt ttttaagtta
    90481 tctgcaattc cagctgactg tctggattgc caaacaactg catgatagat tggacgtcct
    90541 gtatcttttt cccatattac tgttgtttca cgctggttcg ttatgccaat cccagcaatc
    90601 tgatttggtt tgatccctga ttcgatgaac gctccggcaa taactgactg tacagaattc
    90661 cagatttcat ttgcatcatg ttccacccaa ctttcttgcg ggaaatattg cgtgaactct
    90721 ttttgagaac tgccgatgtg tcttcctttc ttgtcaaaga taattgctcg tgagctagtt
    90781 gtaccttggt caatcgccat gatatacgtt gattctgtca ttgtgattcc ctccattata
    90841 tgcaaacgct ttctttaact actcttatca tactactgtt ttaaaaaaag aaactgtcaa
    90901 aattttattc tttttttctt tttttgacag ttttttatta tgaagctatt ttttaatcaa
    90961 ttcttttctt ttttcagcgt ctctattctt cttttcaatc gaataatgtc gtaaggtgac
    91021 gcaaattctg acagataata ttcacactgt tttttgtttc tctggcaaaa tgtgatcacc
    91081 aaatcatatt ctttaccttc ttcataactt ccaatctcaa taccgccgat tcccctcagt
    91141 tctctgatca gatattgttg aaaagcaata cgataaatcg gcagactttc taaatcgatt
    91201 ccaatcacta ctggttttgc aatataaaaa tcgatcatca aaagaacatt ggcatactgg
    91261 atcatcaggt aactaagctc actatcttca gctcttttcc tcggcaattg ctgcaccgct
    91321 gtttcctgta atttcgccag taactgtgtt aaggaatgcc cgagcatttt ctgctgctgt
    91381 tccaaaagcc gatcacgctc atagacttcg atctttccaa caaagaaaaa ccattcattg
    91441 ttgatctggg aaatttggta gcctactgcc ttttcttctt tgattttcaa acgacgagga
    91501 cgataatgcc ataacatcgt ttcccgaatg taagtatcta aaacagcggt tggtaacttt
    91561 ttgctccgtg tcaaatcata ctgataaaat atttcttcgt ctactatcga aaaagaaaca
    91621 aaaaagctgt aaaacatcat tgtttcgtat acattcagtt ctgctgctgt tcgactaaga
    91681 tgcatcacga tgattggatc gattgcttga taaagccggt ccgactgata gagtaatttc
    91741 ttttctttca aagttgcgta cgtacttttt tcattcaata gtcttttttt cgtaatcccg
    91801 agccagcaag caatctgtgc ttctgctgat gccgtaaacg ttgtttctaa tacacggtcc
    91861 aatcctagaa tgaacggtct tttttctggt gtattttgca aaaaaagcgg tcgctgatct
    91921 tccgggatat attggaatag ttcataataa aaatatcgta tctgtagctc ttctccgtat
    91981 aattgaccgt ttttgatttg taatccaaat tcctctaaga gctggttcaa ttctttgatc
    92041 tttcgaaaaa cagaagactc actgatatta aacgctgtcg ctaatcgaac gatggatact
    92101 tgctgatgtt ctaataaata gacgagcatc ttaaacttca agctttcctg caataaaaac
    92161 aatagaattt tttccaaact tacatcttcg tccaacacaa gcagcgcctg atactcattt
    92221 cgctgtactt ctactttttt ttccatcatt cggccaatca attcaatatc ttccaaatat
    92281 tgatcaaacg aggcttttga cagttggaca tgctctctca aaccattgat agaggctgtt
    92341 cccccttgca gaacaaggtt tcgcaaaatc aggatctgta actgctcttt tctttctaat
    92401 aatgcttcaa tcttcatagg cagtattcgc cacctttgac cacaccatat ctggcacacg
    92461 gtattctggc tggaaaaata gctcatgttc ttctaactgt tcaaacgtcc atccttcttc
    92521 tactgcaatt gtcagttggt caagaaggtg gaacatctct tttttgcttt ggagctgtgc
    92581 tccaagaatc tttttttcag aatcaaatag aaatttgagt ttaactttgc tttgatttat
    92641 tgctgtaagc ttgtagtcta cgtatcctgt ttcaattttt tggggataaa aaatgctctc
    92701 ttcttctgtc aaacctacgc ttcctaagaa atagccaaac cactgattgc cgactggacg
    92761 ataggttccc tgatcctttg tctgtgagcc actaattgtc ttgctgacat ttcgtgctgt
    92821 acggacagcg ttatttacta gagaaacata cattttttca tttgttggac gaaaagttac
    92881 ttggatcgca tcgccaatcg cataaacgtc tttttgagac gtttgcaagt agtcatctac
    92941 ccagatcgtt ccatcatcat tcaatgttaa ttgttcttcc cacatctgat tgtcgggacg
    93001 agaatgatta gccagcaaaa caagatcata gttctccttt cttttttccg tctctacaat
    93061 agcggtttca ttttcggtca aagacacaac ttgttcttct aaaaaaagtg aaagcccttg
    93121 atttttcatt tcctttacta acggttctgt catttcagga tctagataac gaaaaagaat
    93181 tgactttcgg ctttcgtaaa gatggatttg tttttttctt gatgccaacc cttcagctat
    93241 ttcgattcct gcttgtcctg caccaataat tgcaattttc tttgcattca tgatcttttg
    93301 ctgaagagcc gttacgtttt gtatcttttt aactgggtga ataagcgttg attctgcaga
    93361 aatatttcga aacttttgat ttgaaccagt cgctagaatc aaacgatcaa aatccaattt
    93421 ttttcctcct gctaaaacga cttttttttc tttcaatcct attactgtct tttctgtgta
    93481 aacatggatt cgatagcggt cagtcagttc ttctttcgtg atccaagaaa gttgtttttc
    93541 actggtaacc tttcctttta atatcaaatt gaacccgctg ggaatccatc ctaacttcga
    93601 ttgcttttca atcaaatata tttcacttgt tggcatcaat tggcgaagat aaatagccgc
    93661 atgaatccct gcaaacgacc cgccgacaat tacaatgttc atctgcattc ctctttctta
    93721 taaggtgttc tactgctaac ttctcaatca gaaaacacag tattcataac tcgctttcaa
    93781 ccttatgata catagcgatg cagcagaatc aaccctctcc atcataccgt gttctaggtc
    93841 tgcttctcaa taatgtacta gtggacctaa ttgaagagta tcatttctga agagatgttt
    93901 caaaaaatgt actcttataa aagaaaaaaa ctcgcctttt acgtacctct gtccaaatag
    93961 gaaacagaaa agaacgaaaa gacgagtttt agcgtgtgta atgtaatagt tagaatagac
    94021 acatcattta tttttaattc tttaatgctt caacaactgc ttcgcctaat tgatgagcag
    94081 attgaggatt ttgccctgta agaagccgcc catcaatttg aaccacttct gaaaaagctg
    94141 ctccagactg atagtttgct cctttttctt tcaaagcatc ttctgctaag aatggtactt
    94201 cattcgttgt accatttgct tcctcttctt cattactgaa cccagtcact gtacgtccag
    94261 ctaaaataga ttttccagac tcatctgtaa ctggcaacaa tcctacaaca ccgtgacaaa
    94321 cagctgagac cagcccttca tttcgataga tttgtgaagc gactttccca agatctattg
    94381 cttctggaaa atcccacatt gttccgtggc caccagcata ataaaccgct gcataatcat
    94441 ttgcatccac atcatcagga cgtaaggtat ttcccaaggc ccgatttctg aaatcttcat
    94501 cttcataata ggcccaatcg atttcatcca tattcaaaac actttgcggt tctaaaggta
    94561 catatccgcc tttaggactg acaaaatctg catcgatccc attttttact aatacatcat
    94621 aaaaatgagt cagttcactt aaccacaaac ctgtaggacg ctcgatcttt tcgtactttt
    94681 ctacatttgt taatacgatc aatactttca ttttcccatc ctctttctat aaaaattgcg
    94741 ttattgataa cgtgctttca agaaattata taatgggctt ggcaaataaa gctctttata
    94801 tgcttcttca aaaggtttcg ttacaaattc atcctcacgg ttttccaata atttctctgc
    94861 ccagtcagga tcgacgatca tttgctgtcc aattgctgca agttctgcat atttcaatac
    94921 ctgctctaca tcttcgcgat tgcggatccc accgacacca actaaaggga tctttccttg
    94981 aatcgtgtta tggaccactt caagaatcga tttatcgttg tatttatcag aacgagctat
    95041 tcgatcatac atatttaatg aaacatgcag ataatctagt tttgactcac gtaatcgttc
    95101 aagaagccag atcgtgtctt caaaacggat acctggtgtt tcatattctt ctggtgagaa
    95161 acgataccct acgatgaatg gttttttagc atattgttca accgctgaga aaaccgttgt
    95221 taataattct tcaataaaac gataacgatt ttccaagcta ccgccccatt gatcctctcg
    95281 tctattcgaa tgcggagaga aaaattgttg gatcaaatac gtatttgctc catgcaactc
    95341 gattccatca aatcctgatt caatcgctct acgtgtggct ttgccaaatg cttggattgt
    95401 ttcaacgatt tcttcttcac tcattgctcg tggtgtttcc gcatcaggac gttttgctgc
    95461 aactgcactt gcagatacag gctgttctcc agataaagtt gctcgacttg tcattcgtcc
    95521 accgtggaaa atctgaataa tcgcttttgc gccttctcct tggattgctt tcgctagctc
    95581 acttaatcga ggaatcattt catcatgagc gatgctgagt tcacctggcc agccttttcc
    95641 gatatcttgg acatttgcag caccagtaat aacagcacca agacctttag aacgttgttt
    95701 ataataagtg atctcatctt cggtgatcac tccattgaaa aagctgagtt gtgtcgtcat
    95761 aggcgacagc atcaatcggt tcttcaattg aactcctgaa ggtaaagtaa ttgattgatc
    95821 aaattgtgac attgtcattc ctcccataat tcgctctgat taacctatcg agaatcatct
    95881 atcattaaac cactcgatta gttgtacatg caactaattt gcttaaaaaa ttttattttt
    95941 tttgtaactt atctgttgca tcattcattg tctgggctaa ttctttactt gcttcatttc
    96001 ccaaaactgc tttgtatgac tgatgaagtt cttcccagct accatcgact tccttagcaa
    96061 attggcgtcc ttgttctgta agataaacta atgacaagcg accttcgcta actgttttga
    96121 cgtatccttt atattctaat ttttcaacaa aacgagcaat cgttgatggg gcggaataga
    96181 gcatttgtgc aatatctttt tgtggtattc catctttttc ttttaatatc aataaaataa
    96241 aaccataagt tggtgccaga cctgtccttc taaacgcttc atcagctaat ttattcaaca
    96301 tgcgatctag ctttttcacg ctaaagaaaa gacattcatc taacgctttt tcaattggct
    96361 tttccatttc atcccctcca ttggcgtaca tatcatagta tgatttttat tttttgtcaa
    96421 aaaacacgga ataatgtccg cctcctctgt ctagatttga aaaaaagaag tagccatctt
    96481 caaagaattt cggcttgttt tcgacaaaac tccttctgga acaccgtgaa tcagaggttg
    96541 tgaaaaagtc gtttagtttt gagtatgaag aaaaattttg tgaaaatggc tttccacatt
    96601 tttgcataaa tttggcttaa taccgaaaaa ctggcttttg aacaccgttt atatcagagg
    96661 ttgtgaaaaa gccgtcctgc atcaagtaat aagaacagcc aaacaaaaat agttcctcat
    96721 attttgtcgt tttttgagct aatgccgatg gtcagctgat tgtacaccgt ttattgagag
    96781 gtcgtgagcc tgccgttgaa ctccgagtca caaggagcaa tttcaaaaaa cagcttctca
    96841 tgttttatga ctatggtgac ttgtgatcga ggagttggca ggagaatact gtttattcgt
    96901 aaagaagggg ctgtgacaag acttttgtca cagtccctta tttcctttta ttataggatt
    96961 tcgccatttg attggatgac ttgtctgtac caatcaaatg attttttctt taaccgtttc
    97021 tttgtgccat tcccttcgtc atcttgatca acatagatat atccataacg ttttgacatt
    97081 tgtgaagtag aagcgctgac gatatcaatg cagccccacg acgtataacc aaataaatct
    97141 actccatctt tgatagcttc cttcatctgc tcaatatgct gcttcaaata gtcaatgcgg
    97201 taatcgtctt gaacggttcc atcttcttct actttgtcta tagctccgag tccgttttca
    97261 gctatgaaca gtggtttttg atacctatca tataattgat tcaaagcaat tctcaaaccc
    97321 ttaggatcaa tctgccagcc ccattcactt gatggaagat acggattttt aattcctcca
    97381 gttattaagt ttccttggac cccttcccaa ttttctggat gagcactgac tgcactagac
    97441 atgtagtagc taaaagaaac aaaatcaaca gggtaggctg ctaagatttc ttcatcacct
    97501 acttctattt ttaagttgac acctttttct tcaaacattc gttgcgtata cgctggataa
    97561 tatcctcttg cttgaacatc actaaagaac aaagaagttc tttgctgctc aattgttttt
    97621 tgaatatcat ccggatcaca agaatacgga acaagaagct gatagctgat catacaaccg
    97681 acttgtgaac ctttgataat ttcatgacaa gcttttgtag ctaaagcact tgctataaac
    97741 tgatggtgtg caccttggta tttcgcttgt tccaaatggg gatggttttc ttcaattact
    97801 cctacgctaa caaaagggtg atgttttaca cagttgatct cattgaaagt catccaatat
    97861 tttactttat ttttatagcg tttgaatact gtttcagcga aacgaacgta aaactgaata
    97921 agctttcgat taggccatcc accatattct gtaaccaaat ataacggcat ttcataatgg
    97981 gaaagagaaa cgactggctc aatcccatat tttagacatt cgtcaaacac ttgatcataa
    98041 aaaaataatc ccgcttcatt gggtgtttct tcatcaccat gaggaaaaat tcttgtccat
    98101 gcgatagaca tccgatagca tttaaaaccc atttcagcaa ataaacggat gtcttcttta
    98161 aagtgatgat agaaatcatt tccgtgtctt ttaggataat aatacttgct gttgggatcc
    98221 tgcgccgctt ttacttgctg atgcgtcatc atatgccatt gatctgtcca tttttcttta
    98281 ggtaaatcgc tgtcgaatgt atacacatca gacacagata atcctttttc atctacatcc
    98341 catgcacctt cacattgatt ggccgctgtc gctccgcccc ataaaaatcc ttctggaaat
    98401 tttttcatat cgatccccct aaacttgcta gttttcttgt ttgattattt ttcttatgac
    98461 tagtaatgat atttttgaat ctactactat ttgtaacaat aaccattgtg gtcggatcat
    98521 atccctcttt gattaattct tgcaaatcta cttccatcaa taaatcgcct ttacgtactt
    98581 tttttccatc agatactgca ctttgaaagt atttgccatt taaattcact gtatcaatac
    98641 cgatatggat cagtatctct gctccttctt cactgactac cccaattgca tgtttcgttg
    98701 gaaaaactgt tgaaacttcc ccgtttacag aactgtagat ttttccgtcc gttggaatga
    98761 tcgcaaaccc ttctcctaaa gatccactag caaatgttgg atcgtttact tcagataaat
    98821 caattatttc acctgctgca ggagtactta acactatatc ctttgaggat tcttcttcga
    98881 tttcatcctt gtagccgaaa agaaaagtta gcatacagga actgatcatc gctaagaaat
    98941 aactagcaac tagccaaaca aatccttcac caatataaat cgggaaagac aaaatacttc
    99001 ttgtagcaac tgccaaagca ccggctcctg cggcaccagc tactccacca aatatagctc
    99061 cacatataca agcaatgtaa aatggtcgtt tatatttaag agtcacacca taaacagcag
    99121 gttcagtgat tccaaataat gctgtgataa atgcagataa agataaactt tttactttct
    99181 tatttttcgt tttcaaaaat accccaagta ctgctcctgc ttgcgcagct acggcagtca
    99241 tacatgctgg acctagcgta tcacgaccgt agaaagaaag attgttggtc attactggta
    99301 caagtcccca atgtaaccca aaaatcacta acacttgcca aaatccgccg ataacagcac
    99361 cagataaaac agggctaaag ttataaacag ctaaatatcc agctgcaatc agctgacttg
    99421 cataatctgc aattggacct acaactaata aaataattgg gaccatcacg atgatacaaa
    99481 tgaatggtgt caataaattt cgaatacttt cgtgcaagct tttgcgaatc ttaggctcaa
    99541 tataagaaag aacccataca gctaaaattg ctggaataac cgtacttgta taccttgcta
    99601 gaatcacggg catccctaga aatcgcaagg ttatgctatc actatatgca ctgacaatcg
    99661 taggataaac gagagctgct gcaataacca tagcgatgaa acgatctgta ttgaactttt
    99721 ttgcagcagt atatgccaaa aatataggca agaaatagaa aaatgcatca gctgctgcat
    99781 tcaaaatgat ataagttcct gattcagtag ttaataaatt caaactcgta cataaggcga
    99841 gtactccttt gatcaaacca cttcctgcca agacgcctaa agtcggggca aaaacagcgg
    99901 cgatcatgtc tataaaagag tttaaaatgc cttttttctc agttcctctc tttccactag
    99961 atgcatcatc ttctagtttc atttgtttgg ataatacgtc atacacttca tttactgcat
   100021 ttcctactac gacttgaaac attcctccag cttcgactac agtgatcaca ccttctagtt
   100081 gctctacctt ctccttatct gccttcttat tatcttttag ggtaaagcgt aaccttgttg
   100141 cacaatggta aacattgctg acattttctt cgcctccgac aaatcggaca atatctttcg
   100201 ctaattgtga atagtccatt tttacttccc ccttgttaat taatgccgta gcaatccttc
   100261 ttacaagata agtatagttc ttagaaaacg gtttctccat tcaattagta ccccttctaa
   100321 tagcgaacga aactgtacaa tagtgtgtat ggtttactta gccgagcaaa tcactcactg
   100381 cttgaaagaa aacaagtata tcgtttctct tatagtcaaa ggagacaaaa aaaacacgct
   100441 tgatcttcct ttgctgatgt ataagtggta tctcaagctg atactctgtg atttttgttt
   100501 ctacttggct tttgataaga cagcacaaca aagtctcggc atttaacgga agcataacta
   100561 ggtcagaact aggagagatt agttgctgaa tggaatctat ctttttatgg atttttattt
   100621 gattttcttc tttgtagtaa tgatcaagca gttttgtttt ctttttttct tcaactatgg
   100681 tcagcttttc acgcaaaatc tgataaatct cccaagattc aaactcatct agaacactag
   100741 gtagataaat caaatcatcc cactcaaaaa taagctcttg ctcagtagtc aaaattgcat
   100801 catattccgt tattttgttt gattgatttt tgaaaagata cactggttct atccggcatt
   100861 ctttgatcca catgttcata ctttgttgaa tctgtttttt tagtgtattc aaaatactaa
   100921 ttggctggtt actaacaatc agtatctccc cttgttttcg aaaaggattc aacgcttcgg
   100981 caagatacaa aacaaaataa gcgctttcag ctaaattggg acgtaattga aaatgtattg
   101041 ggaagaaacg ccgaattaaa taaatttcta aaggataacg ggagatgatc ttttgtacaa
   101101 aatgattcat ggtattatgt ccggcatcca tcctcgtttt catttgtttg atatgggtta
   101161 gcaaaaattc tgtttcatgg aacaataacg aaacaggaag atctaaaaaa cgaataatcg
   101221 tttgctcaaa tgctcttaga ttcttctcta tttctttgtt tttttcatca ttaatcatca
   101281 aataatttaa ctctaatagt cgattttcaa ttgcttgttt ttcttgattg gaaaaagaat
   101341 agggtagttc tgatgataac ttttttgtga gggtctctac catcggaata aataatgtat
   101401 acctgtttgt tttttctaaa agttcttctc ttcgaagaat ggtcaaaacg agataccgag
   101461 aaaatcgtat gaagtcctct cctgaaacaa tataattata tgatataaga acctctttta
   101521 atgtcttttg gacagtcggc atgatattgg aaaaaattgt actgatttgt tgaggcaacc
   101581 ttgcgtgttg gatcaccgtt tctgttccaa caagagataa gaaaattctt tttgaatttt
   101641 cttcagcaat gatttttagt ccttttgtcg acgaaacttc cagttctaat ttaggattgc
   101701 gctcgatcca acgcaaaatc gtttttattt gtaatgatac ggctgttttt gaaagaaaga
   101761 aaatgtctgc tatcttttgc atactgacat accctttttg aaacaataag tacgtcacaa
   101821 tagttgaagc tcggaaatcc atgctggaat agattttatg tttcgtcacc tcttgtatga
   101881 tttgctgttt agtttcagat tcaattgatt ctaaaaaata acctgaacgt ttatttgact
   101941 ggataatgat tttcttctcg tagatagcaa gcatattttt gatttcagtt tggatcgttt
   102001 tcttgttggt acctaaagct tcagctaatt cttcgcttgt tatccaatga ttcttatttc
   102061 ttaatactac aagaatttgg agttgtcgtt tatttaagtc catttgctta cacctcctct
   102121 ttgttataaa catacaggaa aaacctctca aatgacaata gtcacttgca gaggtttaaa
   102181 aatcatttga agaaagatct atattcaagg tttttaccat tagactggat aatttgttta
   102241 taatattcaa aactatcttt tttcaatctc ctaaagcttc cgctcccatc attttgtcta
   102301 tccacataaa taaagccata tcgcttcctc atttcccctg ttcctgccga tacgatatcg
   102361 attggtcccc accataagta accaatgatt tggcaaccat cttttattgc ctcagcaatt
   102421 tcctgaagat gtatttttag atactcacaa cgttttggat cgtggattcg attcaattca
   102481 tctggtgctt catctagtcc aatgccattt tcaactatga ataatggtaa ttcataacgg
   102541 tctgtcaatt cattcatgac ataacgaaac cctagaggat caattggcca actccaaggt
   102601 tcgggagatt tttccttcaa aaagggatta tcgaaaccat ttgctccgcc agtatctacg
   102661 cgcatttctg cttctttttt atagacagcg ctacgataat aactaaatgc aatataatct
   102721 gccgtgttag cttgcaagca ctgttcgtct ccatctaaca ttactggtgc acagtcttct
   102781 tccttccatg tcctgtaaat ataagctgga taatgccctc ggcacatgac atcggagaaa
   102841 aaccatgaat tgcgtttaaa ttgcagtgaa ccaaatacat tctctggatc acagtcatat
   102901 gcataagtcg ctaatgcaga aaagctacac ataataccca tcttagcatt tggatcgatt
   102961 ttctttaata attgagtagc acgggcgttc gctagaaaca tatgatgaca ggcttgataa
   103021 atcacttttt ttgttagtgt agcaatgggt tcaagtttat ctctagcagg gaatgtaacc
   103081 aatccagcag ctgcataagg catacgaaaa gcattattga tctcattaaa ggtcatccaa
   103141 tatttcactt tcccttggta gcgttcaaag acggtctgcg cataaaattc aaaaaagtcg
   103201 attaattttc gattttgcca ccccccatac tctcctacca atgctaaggg ggtttcataa
   103261 tgactaagag taattactgg ctcgatatca tatcgattta atgtattgat tagtctgtca
   103321 taaaatacga gaccagcctc atttggcttc tgttcgtctc ctcttggaaa tattcgtgcc
   103381 catgagatgc ttgttcgaaa agcttttaaa cctaactcct tcagtaaacg aatatcctct
   103441 tcaaatcgat gataaaaatc aatcgcttca tgagaaagat aatggagtga ttcgtctaaa
   103501 gcaatctccc aaatcttttt ttcttcattc cactgaatac taggatgctg gttcatgatc
   103561 ccgataagcg tatctgtcac attaggtaat ttgccgtctt ccaaccatgc accttcacat
   103621 tgattagcag ctactgctcc gccccataaa aaattttctg gaaatatttc ctgatccata
   103681 actatctctc ctcgctatca acaatttctt acttgaagta tagctcgatt catcaaaaca
   103741 agatattcta actatttcgg cagaagagaa gaaaaaaatt gaatgctact cttcattttt
   103801 aatatttata tataacaaat acataagacg atccccgaaa gaaaacactc gttaaccatc
   103861 taagcaaacg atttatttta cttccaacac aaatgcttca taaggtcgta aatcaacttt
   103921 gccgtctggt aactgtttca gaggataatt tgacacaata acccttaaag cttcacgtgg
   103981 aatagtgaac gtctgctttt cactggacat attacaaata acgagccatt gctggtcttc
   104041 atatatgcga gaataggcaa agacatgctc aggcgtcttt tccactaatt catagtctcc
   104101 ccagacgatg atgtcatgtt ttctacgcaa atcgatcaat ttcttgtaca tataaaaaac
   104161 agaatcttga tctgctaacg cttcttctgc attgatttct ttataatttg gattgactcg
   104221 aagccatgga attccagtag taaacccagc atgttcacgg gcgttccatt gcataggcgt
   104281 cctagcattg tctcttcctt tcgccttgat tgattccaag atttcctctt ttgtaaatcc
   104341 agaagaaatc ctttcgttat acatattgat tgtctcaata tcttttgctt ccgcgatatc
   104401 atcgattggg caattcgtca tgcctaactc ttctccttga tagatataag gggtgccttt
   104461 catcatatgg agcaagatag caaacatctt ggcactttct tttcgataca catcgtcatt
   104521 tccccaacga gaaacaattc gcggaagatc gtgattattc caaaataaac tattccatcc
   104581 ttcatcacct aaagatgttt gccatttgga taatactttt ttcagttcag agatactcaa
   104641 gggtttcaaa tcccatttgt ctttgccttc ttgctgatct aatcctatgt gttcgaattg
   104701 gaagaccatg gataattcat ttcttttagg attggaataa agtttagcga tttcggtagt
   104761 tgctccccat gtttcgccaa cagtcatcag atttttgtca ccaaaagttg cttgattcat
   104821 ttcctgaaga tactcatgca gtttaggtcc attacttgtg atttctttat ccggttcttt
   104881 gccaatcata tcgatcacgt ccatacgaaa gcccccaata cctttatcga tccagaaatt
   104941 catcatttga taaatctctt ggcgaacctg tttatttttc caattcaaat caggttgacg
   105001 cttgctatac aagtgcagaa aatattgccc cgttttttca tccaactgcc aagcagaacc
   105061 actgaatatt gagcgcaatc tattaggctc ttttccattg accggatcac gccaaatata
   105121 atagtcccga taaggatttt ctttattttt acgggcctca atgaaccacg gatgttcatc
   105181 agaagtatga ttcaccacca gatccatgat gatacggata tttcttttct ttgcttcttc
   105241 aatcagttct tccatttctt ccatcgtacc gaattctgcc atgattgctt gataattact
   105301 gatatcatac ccattgtcat cattcggaga ctcgtatact ggagaaagcc aaattgcatc
   105361 aatacctaaa tacgccagat aatccaacct ggaaataatc ccccgcaaat ctccaatacc
   105421 atcttgattt gaatcttgaa aacttcttgg atagatttga taaacaactg aatggtgcca
   105481 ccatttttgt tccatgattt tcctcctata aatggatgtt tctatttttt gcttaatcat
   105541 ttattttagt ctctctcact aaaaattgta acgctttcaa atagctattg caccttgtta
   105601 tcggtaacag aataaaacaa aaaaacagct gaggaaattc cctcaactgt tttttgaaag
   105661 gattgattta tgcagggaag aatgctgatt tcacaacttc tttataaacg gtgttcactc
   105721 agctgtccct tggtattagc tcaaaaaacg gcaaaatata agaaactatt ttttcgtttt
   105781 tttctctaat actcaggcca gaacgctgat ttcacaacct ctttatttca cattcaatat
   105841 ccacatgaat cccacaaata caaagaacag accatacatg attggagata cttcttttcc
   105901 tcttttagct gctaacatgg taattggata gaagataaaa cctaatgcaa tcccatctga
   105961 aatactataa gtcaaaggca tgccgatcaa gatcaagaat gaagggatcg caatctctaa
   106021 gtttccccat tcgatttgtc gcaaagattg tgccatcaat actcctacca taatcaatgc
   106081 tggtgcagtt acttgtgaag taacaactga tagtaatgga gaaaagaaca agcctaacaa
   106141 gaagaaaatc cctgtagtaa tagctgtgat acctgaacgt cctccaacgg cgataccagc
   106201 tgatgattct acaaatgcac caacaggaga agtaccaaat aaggaacccg caagcatagc
   106261 tgttgaatca gaagctaaag ctttccctac acgaggcatc ttgttgtctt tcatgaaacc
   106321 tgcttggttt gctaatccaa ctaaagttcc tgctgtatca aagaaagtca caagcaagaa
   106381 tgtcagcact acgacccaca tttgaagaga attgatgtcc cctacatgtt ttaatgcaac
   106441 taaaaatgtt ggtttcaaac ttggtgctgc ggcaacaatt tcagaaggca ttggaatcaa
   106501 acctgtgacc agacctaaaa tcgttgtagc tgccatcccg atgaagatgc cacctggtac
   106561 acgccgaaca agcaagatag cagttacgac taatccaaaa atcgtcaacc aagtagaacc
   106621 aacgttgagt gatcctaatc ctactaatgt agattcattc gaaacgatga tcccaccttc
   106681 gctcagacca aggaaagcga taaatagacc gataccgcca gaaatcgcat atttcaaatc
   106741 tgctgggatc gcatcaatga tcatttcccg cagcttgaag attgtgatca aaataaaaat
   106801 caaagaagca acgaatacgc cggctaatgc tgtttcccat ggaatcccca ttcctaaaca
   106861 aacagaataa gcaaaaaaag cattgatccc aagagcaggt gccgttccaa ttggataacg
   106921 ggctaatacc cccattaaaa cacagccgat cgcactggct aatgcagtcg cagtaaacac
   106981 tgctccttca tccattccag aagcacctaa tacagttgga tttacaaata agatataagc
   107041 cattgagata aatgttgtaa atcctgccag tacctcacgt tttaccgtgg tgttcaattt
   107101 ttctatttcg aagtaggaaa gtattttttc cttcatcttc catcccccta aatccgaaca
   107161 ttataaataa agtccgttaa aatttcgatt tattaataaa acaacgtgtt ttatcatata
   107221 ctaaaacaaa acataagtaa acaaaaaatt cggattttaa gcaaaatccg aacgttccat
   107281 ctgattaaat ccctttatct caaagttcat gaacattcac tttggattac aagaatttct
   107341 ttattgtgtt aataaagttt cttcattcta gtctcaaaaa tcaatagtgt gatttgattt
   107401 taccatttcg tttctgttct tctttgatga attcttttgt atcgacagga ttcagattat
   107461 ttagtccgcc aaaacctgta tcgaccattt ttccccagcc ttttgtcttc ttttttcctg
   107521 atttgagatt ctttgctcga agcttctcac tatgttttgc tcgccgatac ttcaaataac
   107581 cttctaatct tcccattaga tccactgttt ttcctccttt ttattcaatc agacgactca
   107641 gcttttccta taacaaaata attgccttca gggtcagaaa aattgaaagt caagatgcca
   107701 ttgttatctg tgatttctcc tggttcttcc atgttctcgt agatagtttc aaattcatcc
   107761 gtaaaaaata ctaaagaagg cggtggtcct aatacctctg gtgaaaactt ctgcacaaat
   107821 acttttggga atacgcctaa ttctaattct tttgagatgc tgagtacaat actcttaaat
   107881 tcttctggca attcgattgt ttcagaaatt tctgcaccaa ttttttctac aaagaatcgg
   107941 caaatcatct ctacgtcatt gacataaagc atcacacgtg ttttttgtat catcatttga
   108001 cccttctttc tatttgattt tctttcctgt ctataaactg attccattat atcacgaaag
   108061 cgcaaacacc ttgtgtttga tactattcaa gaaaaataaa gcaatagttt ctaggattgc
   108121 tttcctccac aaactttttt tacaaaaaaa aaaacggcaa tgaatgccgc tcttcttatt
   108181 tcgattcttt tataattctg cttctgattc atctttggtt agtgtgtgtc taacactagt
   108241 tacgccaaat gtttgatcga ttttttcctt caacgcttcg attgcctgtg cgccacgtgc
   108301 cgcttgttca gcattgatgg attcaatgac cagcaccgct gcttgtgttt cttccgtcag
   108361 catcgttctt tgggcttcac gccagttgag acagcgacag atcgctcctt gttcatcata
   108421 gtagatgatt tcttccggaa gtgccggagc atcggaatct gcacctaaag gcaggaatga
   108481 ttcgccacct tgggcttttc ctaaatgcag atttcctgcg atcttttcga tatcttctcc
   108541 gccgcaaggt acgccaaaag acaaggaaat actattatag atatctacaa gcggattgat
   108601 tgggaaaaat tcccgttctt gatttgcacg tttcagtaaa gcttcaatag aagaacgtgc
   108661 acctttttta gtcttgaatg tggtaaatgc ctgacgccac tgagcaatga cttcgttttg
   108721 gctgaatgtt tcttctgtaa ggtaatttct tgcttctttt gctgcctcat tcaataattg
   108781 atgatacgtt tcttcacttt cttttgttac gtggttatcg ataccattta cggataagat
   108841 ttcgatggtt gcttcaggaa atacttccca gaaattggta tccactatta cttttttcat
   108901 ctgttcacac ctcttgatta gaataattgc ttgatgaata gatagtctgt ttggggatca
   108961 tctcccatat aaaaaacatg ttcgctgtat ttgataaatc cttttttacg ataaaaagcg
   109021 agcgcaacat cgttgtgttc ccaaacaccg agccaaatgg ctgttttttg cttttctttt
   109081 gctttttcaa tagctgtatc tagtaaaaat gtaccgatac cttgatgttt aaattttttt
   109141 cgtacataga ttcgctcgat ttctaaaaaa tgatcagcca tttcctcaga ttgactcgtt
   109201 cctgtattta gtttcaggta acccgcaggc tcttgatcga tactcactag gaaaaaatcg
   109261 gtttctttat cttttagctc ttctgtaagt ttttctagtg cataagcttg tgtcaagtaa
   109321 tcagctaaat gctccggtga attatctttt ccaaatgtat ctgtaaatgt ttcgatacta
   109381 atttgttgta gtaagtctac atctgaaggc gtcatttttc gaatttcgta tttattcacg
   109441 gcttcttcct ttcaatagat ccttttattg ccttttttga caaaattcca atcttcgcta
   109501 acattcttgc atactttatt taaaagatat tccaattgtt ttgcttcttc gtcagaaaga
   109561 ccatttaatg cgactgcatt ggagtagttg ttttctcgaa tgatgaaagg atagatttct
   109621 gctccttttt tagtcggata gagtttcttg atttttttat tttctttatc ttccaaacgt
   109681 tcgatcatcc cattggattc taatttcttg attgctcggg cagtcgttgt acgatctact
   109741 ttgatcattt ctgctagttt ttcttggatg attccaggat tttcgcaaat acgtactaaa
   109801 taaagatact gtcctcttgt taaatcgact tctttgaatt cgatattgct aatagaatct
   109861 agcgctcggg caatcattcc gatgtctcga aggatttcag ccatttcatc ccacctttat
   109921 tttgtttgta agactagttc acctcttttt gttgcaaatg caactatttt caataaaaaa
   109981 atcaagttct tttttaataa ctagtaaagt atattctttt cttcttttac gaaaaagctc
   110041 aatcacaata gatctggttt ttgttttcta aaataagtaa ctgtttcttc gttgttcgct
   110101 tttctgatag ctttggcaac tcttctatac taaaaaatcc catgttggaa gtttcattat
   110161 tctcaataaa cttggcctct tcaccgtgga tcgcacaagc aaaaacaagt ttataatact
   110221 gaaaaagctg tggaatatct ttttgtttat tcgtatcaaa aactgctcgc aactgagtag
   110281 tttctactgt taatcctgtt tcttcataga cttctttacg cacattttct tcaggagaca
   110341 atcctatttc agcaaatcca ccaggaagtg accattcttt cgtccgttta tcttcgatta
   110401 gtaggacctt gccatctttt ttgatatagg cacgaacatc tacttttggt gttggatgtc
   110461 cttctccaat cgttgtgagc gcttttattt cttcgaaagt ttcttttcct atttcactga
   110521 tcagttccaa tgaaatcgtc cggatctcct caaaacgctc tttatcaaat acatcttttc
   110581 cataatatag accagcttga gaaagtgcga gtagtctttt gtattgagcc aacttcttgt
   110641 tcattctctt cccttctttt ttagcaaatg tatgactatg taatcaagta tagaagactg
   110701 gtttaattac ggcaaataaa tataatgaaa tctgcaataa ataaaagaat gttaaaaaac
   110761 tcgagaacaa aagacattcg acttctctgg ggctgtgaat aaatggcgtt caaaagcttg
   110821 catctgcggt aataagcccc accaaacgaa aaatatgacg agctattctt gtctggctgt
   110881 tcttattaat tgaggcagga cagctttttc acaacctccc cactaaacgg tgttctccta
   110941 ccaactcctc ggtcacaagt cacaatattc atcaaacatg agaagctgtt tttttgaaat
   111001 tgctccttgt gactcggagc tgaacgacag gctcacgacc tctcggtaaa cagcgttcaa
   111061 aagccaattt ttcgatatta agccatttct ttgttactta ttgtcattga tttctttttc
   111121 taatttatcc aatagtggag tgtaatccac ttgagtatag tctgttacat caaattcata
   111181 tagtgttcct aactggaatt tgtcatattt tcggtcggcg atgatctttt tgaatgcttc
   111241 tttcgtaata tgattggtcc ctttcgttcg atcttccaat acgtcaccat agtgataatg
   111301 atccatgata tagctcaaat gacgatctga ttcacgatca cgtttgtacc gacgttgcca
   111361 taacacttca aagtctgctg ttaggcgaat cgtgatcacc tgatatccgt atctatctgc
   111421 taattcttgg agtcgtgctt tttgcttatc actaaaagga tactcggaca caatcacttt
   111481 ctttcctgct tccatataca aatcaagtgc tttgtaatag aaaggataaa ctttcgtcct
   111541 ttcttgttcc gcccgttctt ccaaattgtt aaacccgatg gattctgcat agtattcctt
   111601 gatttcatcg agcgtgatgg catacatatc tggaaatcgt tcccgtagtt tattcataag
   111661 atatgttttt cctgtaccag gactaccagc cagaagaatg aaatactttt tcatctcatt
   111721 tatttcctaa gttaattgga ctttccaagt tcataaacag tccaatctta tgcttgacaa
   111781 tttcttttac tgcttcattt gctggaatca cattatggcg aagagacttg ttgatttctg
   111841 tttcactaaa ggtttcttta gctactttcg tccagttgac taaaagctcc gttccaacat
   111901 tgaatttgcg gatcccgtta ttgatcaatt caggataatc ttcttctttc acacctgttc
   111961 ctccatggat aactaggggg acatcaacta ctgcatcgat ttctttcagc aagggaatgt
   112021 ttacttctgt ttttgatttg aattgtccat gattcgtacc gatagcaata gctaatgcat
   112081 ccacgcctgt agcttctaca aatttcactg cgtcttccgg tcttgtatat accttgtcat
   112141 tttcagcgac atggattcct tcttctgtac cgccgattgt tccaagttct ccttctacgg
   112201 aaacaccgtg cgcatgggca tattctacta ctgcttttgt cttcaggata ttttctttga
   112261 aaggcagatg ggacccatca tacatgacag aagtatatcc gctgtcgatt gcttctttga
   112321 tatcatcaaa gtctcgggcg tggtctaagt gcaagactgc atcaaccatt tcttcttctg
   112381 caatagctgt cattacattg actaacacat gcatgccgat atatttagcg gtatcgacac
   112441 ttgtttgaat aatgatcggc gaacccattt cttttgctgc gcctagcata gcaggaagca
   112501 tttctaggtt atgcgtatta aaagctccaa ctgtaaaatt caactcttct gctgtttttg
   112561 ttacttcttt caatgttgta tacatctttt attgccacct tatcttttta tttgtttcct
   112621 ttgatcgtta cttgttttgc aatttgtcgc atctcatcca ttttgcccat gtagtaatcg
   112681 atcccttgat catcaccagc acgagcagca tctgcacgct tctggttata gaggctcatc
   112741 agttttttat acccatctcc gatcgtctgt ttattttcca aactcttttc taaatattgg
   112801 atggcttgat cgttcacata caattcagaa aatttaagtc caacttgttc ataaagtttc
   112861 gctaatttat gcttatcttg ggtagtggaa atctcttgtt tcaattgtgt aatctctgat
   112921 tgaatctttt cggtcgcttc tggcgatagg gctttttctt cttttgccag aacttttttc
   112981 ggttcttttt cttttttctt aaaaaatcca aacatcattt tccctacttt caattaaaat
   113041 gctttcaaaa ctgggcttaa gatccaggca tataagagtg ctgcggctac tgtatctaca
   113101 tcggttgctg tagcattgat gaatcccatc gaattaaaga tcgttactag caaagcgggc
   113161 aataatgtaa taaagaaacc atgagcaata ccgccaatga tcgctcctcg gcgtccgcca
   113221 actgcgttgc caaatatccc tgctgtccct ccggcaaaga aattggttag cataccaggt
   113281 aaaatcatcg ctaagccgaa catgggcaaa gtaaacatgg caataatcgt accaatcgtt
   113341 gtcgtaatga aacctaaaat gacagcattt gggctataag gaaagaaaac tggacaatct
   113401 aaggcaggga tcgcatcagg aactaatttc atagctatcc ctcgaaatgc cggcacgatt
   113461 tcacctaaca gtagacgtac accagctagc aatacataca cacccactac gaattggatg
   113521 gcttgtaaaa aggcaaacat gatatagttt tgatctcctg ataattcaga agcgaatggt
   113581 tcgcctgcaa ataaaacagt gatgatatat agcgggacca tcacgaccat gacagacaaa
   113641 taagtatctt gcagaaattc gaaatgtgtc ggcaacttga tatcttcgat cgacttttta
   113701 ttttcgcctt tctcaccaaa aagcttagca acaccggctt caaataagta cccgatcgta
   113761 caaaaatgac ctaaagcaat atcatttgat ccagtgattt tacgaatgat cggttgcgct
   113821 actgccggca tagcaatggc gaaacaagct ccgataaaat caccgaccaa gatcaatacg
   113881 atccctcgca gaccggcaaa atagccaaag actgtcgtca tcgttgccat ccataaaatt
   113941 gcttgaccag ttaaaaaaat gtacttccat tttgtgaaac gagccaaaat aatattgaat
   114001 acaaaaatgg ctaagaacgt cagtgcaata tctctaccta aacccaaatc attcattgct
   114061 tgaccattga tagattcaat agaagggatg atcccttgca tatgaaatcc ttcagtaaag
   114121 attttcccga aataagttaa acttccaacg atgatgctcg aaccggcact caacacttga
   114181 aatcctagga gtgtctttaa cgtgccagag atgacttgtc ctgctgattt cttctgcagt
   114241 agtagaccca acatagcaat caatgcaatg gtgatcgatg cctgagtcaa aatattttcg
   114301 atgataaaat tgataacgcc catgttttta ccctcttttc tttttgtatt tagataactc
   114361 ccttatcttg cagaactggg gtgatttttt cttcaatttc attttttgaa acaatatttt
   114421 tcaaatagat catcgccgtt ttaggatcaa ctgcgaactt ttcgaactgc gaacgaaaat
   114481 tttctgctgt gatgatcaca tctggtttca tggaaactgc ggaagaaata tcacaatggt
   114541 ccagtttggc ttctactcct aatttgttca aaacatcctc agcagacatc tgtgctgcaa
   114601 aactacttcc taaacctgca ccgcatacga ataaaatgtt caatttgttc atctttgttc
   114661 tcccccgtat catttattat ttctcaacta ctgaaaaaag cagttgtttg aaatcttcga
   114721 tatttgtgca ttcaatcaat cgatccaact tctcttcgtt gttgatcaat tcaattagtt
   114781 ctttcatgat gttcagatgc gagtaggagt ctactgctgc caaacaaaaa ataatcttta
   114841 ctggatccat ttcaggatta ccgaaatcga ttggttgctc aatcgtagct acgctgactc
   114901 ctaatttatt gaccccatct tctggtcggg catgggctag tgccatgtgt ttgccaatca
   114961 cgatatacgg tccgtaatca ttcactgcac gaatcatcgc ttcgacatag cgctcttcga
   115021 caatgttttc tttaaccaat ggtctagcag ctagttcaat cgattcctcc caagtagtgg
   115081 ctttttcttt gatcatgata ttgctgtccg tcaaaatatc ttttaacata ggctggatct
   115141 cccttttgtt gatttctaaa ttgtttgttt cgaataattt ttctaacttg ccatagatga
   115201 ttcgatctac tcggccacca ctttctttca tgacatctat tatttgagtg aataactccg
   115261 tcgattcatg actgttaggc tctaaccgct gtagttcttc atttcttttc aaaaagtctt
   115321 ctataaccaa gatattcgtc tcagttaaaa tcggatcgac aactaaaagc ggcttatttc
   115381 gataattcaa ttgaaaggtg ctgaaaacca gattgacatc caatttatct actaattcga
   115441 tttcttttga acttaaaact gcagtaatct cgatctgagg aaacttttct ttcagattct
   115501 ctgctaacag atttccagta gccatcccat ggttacagac aacgactgat ttataaacat
   115561 aattcaagtc tcgcttgatt acactggcga tcgtcgaaaa gtggatgaca agaaaagcta
   115621 tctcgtcctc cagtatcttg ccaccaatta cttcttcgat cgtaggaaca aaatgagtga
   115681 ctgcgcggta gattgggaaa taatttgttc ggatgttttc tttcaatgga ttcatgactt
   115741 ggatatgatt cttgattctt acaatcagtg cagccatgtg cttatagaga ttttcgaata
   115801 aagcttcttc ctttagatgg aaaggtacgt gtgtctcgtt ctctacaaat tggatcaatt
   115861 ggatcgttag taattgagct tgtacccact cgattgaatt ggagatatct ctagcattga
   115921 acgtctcaat agtgaaacga agataatttc tttctacttg cgggacattg tccaattgaa
   115981 attcctcgat catgtggtca ataaatgcag aaaagctact gtcttttatt tctgtatttt
   116041 tccaattaat ggcagagata aattcatgtt tcctgattcg ctggatccag atcaatgtaa
   116101 aaagcaggat ttgtttttta taaatatcat cttcttgttt caacaactta ttggaataga
   116161 tctcctgtat ttttttgatt tccaccaaag gaaaataatg gagaaagatt ttttgagccg
   116221 gtgttaattg tgcatcttga ttcataaaga agtcggtcat tcccagattc tgattgataa
   116281 aatcatagat catcgtacgg atagatcgtt ctgaaccttt ataaaccagt ccttgctttc
   116341 cataactgac gatctctatc ccataactga ccagtgttgc tcgtaaccgt ctcatatctt
   116401 catctaatgt acttttagag atttgaaatt cttcttcttt tttgtttaga tggatcggga
   116461 ttcggctgta agcaacggct aaaactagat caaaaatacg ttcgcgccga ttcaaaaagc
   116521 cgtctttcac atcttttatt tcagtttcta atcgagcttg cttttccttt tccagcttca
   116581 acaaaaaacc tttgttgcga attgtacgga tctccggaag ctttttactg ctcaaccaga
   116641 tattcgcttc aagaacttcc tgacggatcg tccgctgact gacattgaac tcacttgcta
   116701 gatgttttgc ttttactgga tattgggctg tcatgattct gtgaagtatt tcaattgttc
   116761 ttgttttcat agaaatgatc tccttctgat ttcaagtata tggttccgct tacataataa
   116821 aaagtagata tttctgccac ttgaagtgga aagaaagtaa gcaaagcaaa caaaaaataa
   116881 gccatatgct ttttcatctc ctcaacgaaa aagacatacg cctattatta caaaaatttt
   116941 gcccatctat acaaaaaaga ggttgtgaaa aagctgtcct gcatcaagta ataagaacaa
   117001 ctaaactaaa atagtgcttc ctatttttcg tttggttgtt cttattatcg cagatgcaag
   117061 cttttaaaca ccatttagtg gagaggttgt gacagagatg ttcagccttg agcgataaga
   117121 agcgattttg aaaaatcgct tcccatattt tacaaaatcg tgccttattg ccgataggct
   117181 atctctggca caccgtttat tcagaaaaag gagctgcgac aaggcttttg tcacaactcc
   117241 gttcataaat atttcctgtc aatccagcat aatcggctga ataaaatcgg cttgccatct
   117301 tttttctttc tcagaaaaat caaaatacca tatctgagaa aaatactgtc gttgtgtctt
   117361 acttcctgag atcaatcgcc catcttttcg atcgactgaa taatcacagc atctgaaatc
   117421 aattcggatg gcaaaactat tttcgtggat ctgtcgataa tttcctactt cctgaatagt
   117481 tattttttta gtatgatttc ttacaccgtc tgctttgttt ttttgcagaa ctttctgatg
   117541 ttcggcaaac agcttgtctg tataacagct tctggctttt tcaggagttt cttcttccca
   117601 agcggattgg atcttcatga atatcttttg gatttccaga aactgtgctt tcttttcttt
   117661 agccgttcct gacatgcggg acaatatctc cgctttcagc cttttctttt gtcttttatt
   117721 cttgacgata gaaaaagcag aaacccctcc tactgacaaa acagctaatg caagaaatcc
   117781 cgtttgctca taactagaag gacctgtacc tggaccataa tacccataag aatctctgcc
   117841 gtaagaacga ctgccaaaat aactgccccc atatgaacga ccaccaaatg aacctctgcc
   117901 cgaacttcga ccgctagatg tacctccacc atgaccaccc gcgacagcga atccttgggg
   117961 cggcagagca aacaaacata ggcccactaa caaaatgatt gctaaataat tgattttttt
   118021 cattgtcttc ctcgttatct tttattacaa aaaactattt ttatgatagc cttgctaaaa
   118081 ggaagagtca ataaccagat gcataaactg tttttttagc aattttgtct tatttagtca
   118141 ttgagtaaca tcggacaaat gtatgtgtcg gcagtccata attcctctat cttcagcatg
   118201 aacaagcttg cagacaagag atctgcgctt cctccaggag agatttggtt ttcctgacaa
   118261 aagtgcaaca gtgctgtaaa tggacgattt ggtaaagcac tttgactagc agcatgagca
   118321 agtttttgca tttccactaa cgttttctga tcactgcgat gcaatacgca tgtgtcatct
   118381 agcgaactca tcaaaactaa caacatatgc atttgtttct gtacatatga atcattatct
   118441 agctccttag ctgcttgaat tgcaagcctg atatgcggat accctaatat cgcttcttca
   118501 tatgcaccat ttacgccata tttttgcttc accctatgac catgagtggt ttttttatga
   118561 cgatattttg tatcaggaaa agcagcaagc ttgctgacat catcaagtat tttcgataaa
   118621 gaaaaaggct gttccatact gattttttgt gcaatgacac tgatcaatag ccccattgcc
   118681 caaatcgctc ctttatgggt attgatgcca tttgtagcaa tcagcattgc cttttccgct
   118741 tttcgcccaa tctcagcaat tctttctctt aactcctgat caatagcatg atgccatgct
   118801 atttgagcca tttcttcaaa aaaaggagtt agcgtcttag cagacttaag aaataaagca
   118861 tagtccatat cggaatgtgc acccgcatcc agtgcatcca ctaatccagg ttttggactt
   118921 aatgttactt ctgcgatcaa tgcttcctct accaacgcag cgagttgctg agtcactgct
   118981 ttttttcgtt cgtcatttat catgacactc actccttctt cctactatta cttgctgaaa
   119041 ccttttttga tagctaccca aatgatatga agtaaccagc ttaaagcaaa tgcacaactt
   119101 gccgtcatta gataagctac aagaatcatg actcctgaag gtaactgcag ccaactatct
   119161 ttaaacaata ataacagtac ttggaaaaca aatacattgg ctaaatacgt acgataagca
   119221 taaacagaca accatttgaa caatggcaat tttggcgaat cgtttacaat cattttggaa
   119281 gcgcctatga agacagcaaa gatgatgact aaactgtata aactttggat cgtattcaag
   119341 taaggtgcat tcgcaaagct caagtctcct ggatgtgcga gcaatgaacg gacagaaaag
   119401 aacgcgataa ctaaggcaac aggtaagaaa agataacgta ctctgtccaa atattgatag
   119461 actttttcgt gataaacaaa tgcggctacc ccataaatca tgaaactagc aacaaaccga
   119521 tctaataagt accagctgtc atgataaggc ccagtcaata cttgtgtttg atagaacaga
   119581 taccatgcga catataaaat cgttgaacca atcaatactg gccatacata ttttttatta
   119641 gcaaatactt tgtaaccgag ccaaacaaaa aacggcatga acaattggat ctgcagcatc
   119701 ataacggtat accataaatg aggcgctcca tcacctgtga catatttcag taaaaagctt
   119761 gcagtatccg tatacggagt ttgttgttgg actgctggaa atagccaaag ataagccgtc
   119821 gtccatagaa gatacggaac gactagttca aaaaactttt ctttcaaaaa ttcccaataa
   119881 gacaaatgct gacttgtttt taccatatta taaacaattg caaaaataaa cattggtgct
   119941 gtgtatttaa cgatgacgta aaaggtacca agaaaagctg tatttgttgc gctgtggctg
   120001 tttgccaaag caaagctcaa tatcgtttgc atcataacag ccgttacagc tgatactttc
   120061 tggaagtcac ttacgttgat tttgattttt ttgttttcaa acatctcttt ctctctcttt
   120121 ttctttatta ccaaagttct ttggttaatt taggtccttc gactgttttc aatagaattt
   120181 ttttctctgg ctctctcaaa tactctttta gtgaaaaacc gccttgccga gtcactactt
   120241 gggtatcgaa ttgctcaaaa aaagcaggat gcgattgaat tacctgaatt ggcaattcaa
   120301 tcggtgaatt tgcgtacagc agcaaatcaa aatcactggt ttcttttact gccggaatcc
   120361 cagtcgataa ttcaaatcct aagctgccgc cgattcccca tttacatcct gataatatgt
   120421 ttctagcagc atgaaattgc tgataaacag gataatccat gattttctct tgtctatacg
   120481 attcttgttc gatgatgtcc cacggatgaa tgacttgttt gacggcatgt tttgagattt
   120541 ctgttgacca tctctgattg cgggcaggtc cacgtaaacc aatcggtagt atttctgcgt
   120601 gatccgtcga cgcacgacga actgttccga acatcttttc agttagaacg acccattcag
   120661 gcaaggtgaa cccttctatt tcatgtttat caaaaaggac aatatcatgt gcttgaatca
   120721 ttttttatgc atcccattct tcgtccattt tggcacggac tttatttgtt tcgacacgtc
   120781 cgaatgtttt ggctgtttcg tttgtgtatc gatttgtcag catcgtgtca tttgtattgc
   120841 ggacatcttg aatggcttca ttgattgctt cgatgacttt gctgacattt tgttctgaag
   120901 cagcttggtc ggtgatatct tctaggaaat gatagatcgc tcctagtttt gtataattat
   120961 tgatatcgta agcgatagct ggaacttttt cagcagctgc ttcgatttca gcaaccgaac
   121021 gttttgtcac acgtgcagca ctttctttag acatcgcttg gacggtaatt tctttattgt
   121081 ttaaagcaat caagcggctt gattgtaatc catgtgctaa aaatgcacct gaaatagcat
   121141 ttcctgcaat caatccaata actggatgtc cagcttgacg gagttttgca taagcagcag
   121201 cactattagc caaagccaca tggataccga tcaattcttc gttatagccg tatgcttggc
   121261 ttggtacatc gatcacaacg atgattggcc gtttcacttt tttgtcttta tcttcttcgt
   121321 aaacgtgatc caaaatttgt cccatgcgga aaccttcaac taaaccaact tcaccgtttc
   121381 gtacacggta catcgggttt ttaggatcag gtacgattga tgtcacgatg gcttcttcta
   121441 tgaatttact tgatttacca taatacacag tactaataga agaagttgga tttttcatgc
   121501 cagttagtgc cgcaaaccaa tcgtaaccaa cacttgctgc agctggttca tttccttctg
   121561 ctacttctgg taagtcaatt gattttgctt gatggttagc aattgcttca ttgtaatcgt
   121621 caatggccat tggttttgaa agatctaaag aatcaagtaa tgataaataa aatgctgagc
   121681 tttcactgcg atgcgtgtct tttcgttcgt ccattgctgc gatgacagca gctttgattg
   121741 cttctacact atcagtcact aattcatcaa tgatttttga ttctacccgt tgacgagatc
   121801 ctaatgtatt ccaaatcaag tctttgtcac tagaatcaaa ttctcgaacg cctgcttctt
   121861 gttcaataac ttctggtcca ttcaaaccga ctctcgcttt ttttgttgcg attaaataac
   121921 tcattaatgc tgaagtaatc gacataccgc caaatgatcc tacacgtcct ggaatcaaac
   121981 cgatgactgg tacatattgt tttagagcaa tgattacatt tccgatttct gaaatagata
   122041 acagtccgta gtttgcttct tgcaaacgaa caccacctgt atctagtaca atgactggaa
   122101 agatctcatt tcctttttta ttttcttcta acacatgttc aagtgcagca acgatttttg
   122161 caccggaaac ttcaccgata ccgccacctt ggaattttcc ttccatagcg attactactg
   122221 cttgtttgcc attgatcgtg ccacggctga caacgatccc gtcatcactt tcagggacga
   122281 ttccttgtgc tggtaaactt ggcgcgatga tttgatcgaa tggatcaatc aattcacgtc
   122341 cattgtcaag tagagcgttc actcgttctc tggcgtttaa ttctacaaaa ctatttttca
   122401 tctgaaagtt cctccattgc ttgcgtcaat cgtaggtaca caactcctgg tgtagcaccg
   122461 aagtcattga tcacgatatc tgctgaaatt ggataacgat caaaaaatct cgttaataca
   122521 ttgttccata cttcgccgaa gccatcgctt cctgtacaaa tttttacagt agattctgtt
   122581 ttttctgttg gaaacatcaa gatttccaaa tctcctgaac cgaccactcc tacatggatt
   122641 ttcttattga tcggctgttt cgttggatat ttataagcta attgttccat ggatctctcc
   122701 cctttttgta aaacagagca tacacgttct gcttattcgt ctttcttctt ccatctgggt
   122761 aaatggcgac aaaaggtttt tctcgccaat tttatgacca agttctgaat ttcattggtg
   122821 gttcatacag gccatctgac cattcgatca aatcatcgat ggtttgtgca gctaataatg
   122881 aacgtttcgc ttcactacgt ttgatgccta gatcttctgg taatttcacg atgccggctg
   122941 cacgcaagct atctagtgat tctttcgtgc tagtcattcc aagaggtgta acaccgccaa
   123001 ttgctgcaat tgctgcttgt cgttcttctt ttgtttttgc tttgtacaaa taagcaattc
   123061 cttcttctgt cacgatatgt gtagtatctt cgctataaat catcactggt gcattggcta
   123121 agcctgcttg tttttgaaca gctagtgcat ctaattcttc gacaaagact ggttttttat
   123181 ttgaaccata tgtttcaacc atttgaacaa ctaatttttg gcctttccct aatggatcat
   123241 cattgtcgcg aagtgattgc catgctggtg tagaatgacg acgaccgcca ggattatgtc
   123301 ccatgttagg cgcaccgcca aaaccagata aacgtccttt tgttacggta gaagagtttc
   123361 cttcgtaatc taattgcaag gttgaaccga taaacatatc gatggcatat tgtcctgcag
   123421 cttgtgataa tgttcggtta ctgcgcatcg tgccgtcttt accgacaaaa aagacatctg
   123481 ggcgagcagc aatatatttt tccataccaa cttcgccacc aaaactatgg atgctttcaa
   123541 cccaacctga ttcgatggct ggaatcatcg ttggatgtgg gttcaatacc cagttcttcg
   123601 cgattttccc ttttaaccct agtgattcac cataagttgg cagtaacaat tcgatagctg
   123661 ctgtattgaa tccaataccg tgattcaaag attgtacgcc gtgttctgcg tagattcctt
   123721 tgattgccat cattgccatt agaatttgca attctgtgat gttttgagga tctcgtgtga
   123781 ataaagcttc taattgataa ggtttatctg ctttcacgac aacgtctacc cagtcaccag
   123841 ggatatctac acgtggtaaa gaatcgacaa cttcgttgac ttgaacgatc acgataccat
   123901 ctttgaaagc tgcagcttcg atgattgttg gtgtttcttc cgtattgaaa cctgtgtaca
   123961 agttgccgtc tttatctgct ttatctgcag ctactaaaac aacatttgga atcaaatcga
   124021 tgaataagcg tccataaagt tccaaataag tatggatatc acctaatttc attgtgccgt
   124081 cttcaatcat ttgggcgaca cgcaagcttt gtgcaccagc ataagagaaa tcgatcttgc
   124141 ttgcgattcc tttttcaaaa atattcaaat gttctggtcg tgagatacta gacatgatca
   124201 aatgcagatc attcactttt tctgcatcta ctttttcaag actttctgaa agaaaacttg
   124261 cttgtttttg attgtcgcct tctaatacaa ctttgtcgcc gggagcaatc agtttttcca
   124321 ttacttctac gattttttca gtttctacat acttgccatt gagcaagttg ctgatttttt
   124381 ccaatcgctg cgcttttttt tcgcgtttag aagcccagtt gcggtttggt ttttccataa
   124441 ttagtcatct ccatttttga tatagaaacg tggcgtcatc aataccatgt tggtctagat
   124501 tgatcgtacg gatcccttta tctacaccaa attttgtatg aatcagcttt gtcaaagtat
   124561 tgccgggggg aaattcaatc gtcagatcca ttcctaattc ttttgccaag tccatcattt
   124621 ggttccactg cacagggaaa gctaggtttt ccaacaaatc tttacgaatc tcttctgcgt
   124681 cctgagtggc tcttccatcc gtatttttta tatacaaaca tctagcatca gatagatgga
   124741 cagactgcat atacggcttg aatttcttga ccgtatcatt catcaagaga cagtgagatg
   124801 gcacagggac tttcagcagc ttcgctgttt gcgcttggtg ccgtttggct tctgccaacg
   124861 taacggataa accttcgata ctcccagata acgtatgttg catcggacaa ttttcatttg
   124921 acagataaac tggatggtca ggatcaaatg tttttgctac aatttcctca gcttcgcttc
   124981 tcgtcacacc tactactacg cccattgcat aaccgcttgg ataagcttct ttcattaaga
   125041 ctgcgcggtg atagactagt tccgctgcat tctcaaatct caaagatcga caagcaacag
   125101 ctgcacaaaa agcaccaatc gaatgtcctg ctgcaatatc aggctgaata ccgttttttt
   125161 ccatttcatc taaataaaat actgcttttg tcagtaatgc tagctggata aaaaccgtat
   125221 cttgatagtt ttcttcttta tcaactaacc gataccccgt cacattttct aaacgttcca
   125281 tgtacatttc agggatatcc gctaacatcc ctaacttctg actgccttgt ccaggaaata
   125341 agaaacctgt actcatgagc ctcgcctcct cagcacttac tttttccact gctatcttag
   125401 tcaatttctg ctataataaa aaatgccaaa aaaagaaaaa accataacaa aaaggtatgg
   125461 atgggatgga taattatgaa attgcttcat ctgcagtatt ttaaaaaagt attcgaaaca
   125521 aaaaatgtta cccaagcagc caaagaatta tttatttctc aacctgcctt gagccgtgcg
   125581 atcaaacatt tggaaaacga attaggtgtc cctttgtttt accatagcgg cagaaacatt
   125641 gagacgaccg tttatgcaga agaattttat ccatatgcag tcaagacatt agacacatta
   125701 gaagaaggaa tcaaattatt gtcttcggtc aatgagaaga tcgttacttc cgtcatattg
   125761 tatttagagg tagcctctgt ttctattccg aacttggtcc gaatttttat ggaaaagcat
   125821 cctgatatcc aattaacgat catgcaacat catttaccag atgatattac cgatcctgta
   125881 ctgtacatca cttcggagat gaagcctggc atgaccaata ttcctatcat gaaagaacct
   125941 gtttatgtcg ccattcctaa gaaacatcct cttgctaaaa aagaacatct gcaattagaa
   126001 gatatccaac gcacccccat cttgatgctg tcaaagagca acgccttccg tcatacactg
   126061 gatgcagcac ttgaagcgaa aagtatcgaa ttgacgatca gttcgacgac agatgatcct
   126121 gcgacattac gttctattgt caagcaagga ttagctgtta gctttttccc aaaagtttct
   126181 tggtcttacg ataaaaatga tcctttcgtc ttgcgggaaa tcaaagattt gcccttgaca
   126241 cgaacaattt atttatcttc tagcttcaca gaagatcatc ctttgatcaa aatgattgca
   126301 aaaacgatgc gggaatttta tttaggaaaa taaaaaaaaa agagctggga caaaattctt
   126361 gtcgcagctc ttttttcgaa caaacggtgt tccagaagta atttcttaga aaataagccg
   126421 aaatttccca aaaatttgag aagcaatttt cgtaaattcc ttcttatttc ttgaagctaa
   126481 acatttctgt cacaacctct tctctattgt cctagacatt cattgcgttg atttaaaact
   126541 tccatcaatc aaatctgcta gttcatctag cttttctatt ttacgtagat caatagagat
   126601 ccaatgttct ttattcatgt gataggctgg aaaatacccc tcttttcctc gcaaaattcc
   126661 gccaagttca ggatcgacct tcaaatcaag aatattgatg atcctatggt cacttgcatc
   126721 atcatagatt ttttcttctg gaacagacat caggacccca aaccattttt tgcttttttg
   126781 atgtctgaat acgcaataat caggaaattt tttaaaaata tattctggag acaaattgta
   126841 tgtttcattg atgtgatcga ttagttcttt tttcgttagc atctgcttcc atctctttct
   126901 tattgattcg ctttattcaa agataccacg taagaataga aaaatgaata caagtagttg
   126961 ctaatcaaat acttcgatat ttttcttttt tatcaactct taaatgttca atccgcctgt
   127021 gttggtcttg ctaccatcta ctattaaaat gtttattatt gtttgcccac ctattttttg
   127081 attttagtgg tatcattttt caagttcatg atgaaattct tatcatcagt aaatgctcca
   127141 gaaaaataaa caatgattga aaaatcagtt gaaacttgac caccgtttat tttctccgta
   127201 ttcttagaat agaagggagt ctgattgatg tattcactaa tgaaaaaaat cattaccgaa
   127261 aaagatattc gacgtcatgt ttctttagta gaacaattgc tgaatcatac aaagataacc
   127321 gtaaatgaat tagctgaaat catagggaca accgaacgaa cgattttttc tgaccttcaa
   127381 tctattcgct ctcagctgcc cgaaggctgg gacatcatca gcgatcaagc aggaatcagt
   127441 ttgcaaaacc agcaaaattt attaacaaat gacctttggg agattttttt caaacaatca
   127501 gtcagtgtcg aactgctgaa aaatctgctt tttacaaaaa aagttgctgt ccctgatttt
   127561 ctagccgacc atgggctttc ttatgggaca ttgaaaagac atgtgactaa aatcaatcag
   127621 cgtttagcaa gttacgactt gcagatcgat ttgacgaaat atacagcttg tattcttgga
   127681 aaagagcgtg cgattcgtac tttttatcat cgattgctga ttcctttcac tcataacaac
   127741 tattttttcg aggattattc gatccatgaa tcccattatt ttcaattttt aagaaacctc
   127801 agtcaaactg aactagcggt tgaaacagaa gagattttcg gaacatgttg gttctttatc
   127861 aatacgatcc gtataaaagc gaattgccga ttagattctt ctatccatac caacagcaca
   127921 ctctcctccc tgtatgactc tgcattgaaa aaattgtatt taacggaagg tatttatctt
   127981 aaagacactg agctttcttt tgcttctttc tgctttctgg aaagttggaa ttacaacaat
   128041 aactatggac aagaaaccgc tcgctgcctg catcattctc catttttaga ggtcctcgaa
   128101 acgtttgtag aggaactagc ttcagagctg tctcttgatc aactaaaaaa aacatctctg
   128161 actgataact tggctctcct catattaaaa tatcatgaat cgccgatatt gattgaagca
   128221 ttggaccgtc aataccatcg ttttttagaa acatatgatc agcaatatgc acacttgtat
   128281 caacagaaag agaatttact gaacgatcta aaaaaagaaa tagaaatcaa tgaaccaaat
   128341 tactttctcc aactcttgtc tctactgatc caacaaacga ttttttctat caaaccgaat
   128401 ttgttcaatg tctattttat tttccaagga gaaccttcat ggaaggcgtt cttgcagcag
   128461 gaattaaaag attacttagg aaaacgtgtc tgcttcttac ctatcgaact aaccgatctt
   128521 tccactattt cttttgaaaa aacagatatc ttgatttcca atttccctct agattctcta
   128581 gatatcccta ttgtatacat ttcttctatt ccaacgaaaa atgagctcaa tcgtttgact
   128641 gaactcactt tcaaaacttt tttatagtaa cggctagcga ctgtattctc tagctgtttt
   128701 ttcttttttg cgaaacagtt tgttcatgat ccctttttct atttctacaa ctaagaatag
   128761 aagaatcaca tttgctccaa tcaataactg ttgtgtcatc gttaaactta ctgtaccgat
   128821 cagctgctgg ccgactggta gaaaaataac catcccttgc aataaagcaa ggatacctaa
   128881 tgaaagaaaa agcgctttgt tttgcaaaag accttggttc aatgacggct tggacaactc
   128941 tctgcaattg atcatgtaaa cagcttgagc taagacgata ttttgcagaa gaatggtttg
   129001 ctgtaagctt tgcccttcaa actgcatagc caataaatag gcaggaacca tgatcagtag
   129061 ggagacatag atgatccgaa acaaatgata accagatagg attccttgct ttggatctct
   129121 tggtgggcgc ttcatgattt ctggatctgg cgactcgaac cctagtgcat aagataaagt
   129181 gattgtcgtt accatattga cccataaaat ctgtactggg gacaaaggta gcgggcgatt
   129241 cagcataagt gcccaaatca agatcaatcc ttgagctaat gcagttggca agaagaaatt
   129301 gatggttttt tgcaaattat ccaaaatccg ccggccctct tttacggctt ttgcaatcgt
   129361 atggaaatta tcatctccta aaaccatatc agctgcctgt ttgcttactt cactaccttt
   129421 gattcccata gcaattccta catcggatct tttcaaagca ggtgcatcat ttacgccgtc
   129481 tccggtcatt ccgacgattt ctccattttt ctgcaaagct ttaacaattc gcagtttatg
   129541 ttctggtgtc gttcgagcaa agacatcgac tattggcact tgctgaatca actcttcatc
   129601 agacataaga tccaaatcga tcccttctaa aactttggca gtatgtttta agccaatttg
   129661 ttccgcaatc gcttttgctg tgtctttgtg atcccctgta atcattttca ctgagatccc
   129721 tgcttgttgg cattccttta cagctttgac tgcactttct tttggcggat cgatcaatcc
   129781 ggcgatccct gcaaaagtta attgggttaa agtctcatgc gtgagttcct gtttcgaatc
   129841 tactttttta taagcaaatc ctaaaacacg ctgacctttt ctcgcaaatt ctgcagctgt
   129901 ctgactccat gcttcttgtt ctgcagaaga aagagttgat ttagcaaata atacttctgg
   129961 tgcacctttg acgtaaatca ccgctccttt ttcctccgca tgcatcgttg ccatatattt
   130021 gtattcagaa ctgaacggaa tctttgcttc tatttttttc aaaggtagat tggctgtttc
   130081 tgtgtgtcga atcagcgcaa cttctgtcgg attgccactt aaattttctg ttttctgttc
   130141 ttcttttgtt tttaattcct gacagttttt cataatggac aacacgcagg cttcttcttt
   130201 tgcagctaca tccacaactg tcatttcatt ttttgtcaat gttcctgtct tatctgaaca
   130261 gatcactgtc atagaaccta atgtttctac cgaaggaagt cctttgatga tcgccttttc
   130321 ttttgccatt tcatgtactc caacggatag aatcatggtc aaaacagctg gcaatccttc
   130381 gggtaccatt gacaccacca aagcaatcgt agccgaaaga aggatatgcc aatccatacc
   130441 atatcgaaat gtcgtaaaaa taactaagaa taggctcaaa caaagaatgc cttgaaaaat
   130501 ttgtttgttt aatcggttga tttttttaat cagaggcgtc gtttgttgtt cgaccgattg
   130561 caatgcttga ttgattttac cgatttctgt cgtgtttcct gtttctacaa cgacaccgac
   130621 tgcagaacca gattgtacaa gcgttcctga aaaacccata tttttctggt cgccgatcga
   130681 ttcttcttct gtcaaaacgg catgactttt ttcagatgct tctgattctc ccgtcaaaat
   130741 cgattcttcc actaataaat catgtgcttc gattaatcgg atatctgctg gaacgacatc
   130801 tccggcacgt aagacaatga catctccttt taccagttct ttcgcaggga ttttttcttg
   130861 catcccgttt gatagtacta tcgcttcttg tcccatcagc tgcttcaaac cattcaatga
   130921 ttcttccgct tttctttctt gccagtaact aacgagtcca ttgacgatca ctacgaataa
   130981 aataatactt ccttcaatat attcactaga agcaaatttc aaaaaagagg caatgatcaa
   131041 cacgatcatc agcagatcag taaaatgctt tgctattttt ttccatcgtt ttgtctgctg
   131101 ccttgctttt atttcattat atccttgatc agtcaggcgt ttctgtcgtt cttcttgcga
   131161 caagccttct gttgatgttt gatagttttt caatacatct tctaccgtca atctgtacca
   131221 gttcatccta tcccctcctg tttaattgat actgttatta tacgcaggga agttttttca
   131281 ggcgtatcga ttatttcagg ggggtctgaa ataattcgtt ttgcaaaatg tatctgggcc
   131341 taactgatat ttctattgct tattctttta tatacaaaat ttaagaatac aaaccagata
   131401 accaataaaa aaggaataaa gcgtgtcgtg ctttcgaata acaagctgaa agcaattgaa
   131461 gtaaaaaaca ccaacaaagc aagatcttta tatctttgtg tagtgttccg tttcttttct
   131521 ttaataaatt gaacatgtgc acacaagatc gaagaccaca caaatagaaa acaactcgtt
   131581 gtcatgcctg ccaaaagctg aaaaaacaat cgactatcag ctacaaaaaa atgtagacaa
   131641 agaccggcaa aaaataacat tcctgtaatt aaaataccgt gtaaaggtac gcctttctta
   131701 gaaagcgcac aaaaccaatg gggcaaactt ttttctttt
//
LOCUS       DADVXM010000002        88930 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.002, whole genome shotgun sequence.
ACCESSION   DADVXM010000002 DADVXM010000000
VERSION     DADVXM010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 88930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.002"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            80..1204
                     /locus_tag="KB927_000115"
     CDS             80..1204
                     /locus_tag="KB927_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6839069.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            1431..2348
                     /locus_tag="KB927_000116"
     CDS             1431..2348
                     /locus_tag="KB927_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6839070.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            2341..3174
                     /locus_tag="KB927_000117"
     CDS             2341..3174
                     /locus_tag="KB927_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6839071.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            3257..4375
                     /locus_tag="KB927_000118"
     CDS             3257..4375
                     /locus_tag="KB927_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6839072.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            4369..6267
                     /locus_tag="KB927_000119"
     CDS             4369..6267
                     /locus_tag="KB927_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBB6839073.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            6261..7484
                     /locus_tag="KB927_000120"
     CDS             6261..7484
                     /locus_tag="KB927_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6839074.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(7570..9504)
                     /locus_tag="KB927_000121"
     CDS             complement(7570..9504)
                     /locus_tag="KB927_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6839075.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            9730..10386
                     /locus_tag="KB927_000122"
     CDS             9730..10386
                     /locus_tag="KB927_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBB6839076.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(10460..10813)
                     /locus_tag="KB927_000123"
     CDS             complement(10460..10813)
                     /locus_tag="KB927_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBB6839077.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            11005..11934
                     /locus_tag="KB927_000124"
     CDS             11005..11934
                     /locus_tag="KB927_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBB6839078.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            11945..12781
                     /locus_tag="KB927_000125"
     CDS             11945..12781
                     /locus_tag="KB927_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBB6839079.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            13029..13805
                     /locus_tag="KB927_000126"
     CDS             13029..13805
                     /locus_tag="KB927_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6839080.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            13981..14724
                     /locus_tag="KB927_000127"
     CDS             13981..14724
                     /locus_tag="KB927_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6839081.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            14717..16297
                     /locus_tag="KB927_000128"
     CDS             14717..16297
                     /locus_tag="KB927_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBB6839082.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(16548..17027)
                     /locus_tag="KB927_000129"
     CDS             complement(16548..17027)
                     /locus_tag="KB927_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBB6839083.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(17043..17795)
                     /locus_tag="KB927_000130"
     CDS             complement(17043..17795)
                     /locus_tag="KB927_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBB6839084.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            17912..17982
                     /locus_tag="KB927_000131"
     tRNA            17912..17982
                     /locus_tag="KB927_000131"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17944..17946,aa:Gly,seq:ccc)
     gene            18343..19068
                     /locus_tag="KB927_000132"
     CDS             18343..19068
                     /locus_tag="KB927_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBB6839085.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            19323..19589
                     /locus_tag="KB927_000133"
     CDS             19323..19589
                     /locus_tag="KB927_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBB6839086.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            19586..20017
                     /gene="ruvX"
                     /locus_tag="KB927_000134"
     CDS             19586..20017
                     /gene="ruvX"
                     /locus_tag="KB927_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBB6839087.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            20042..20347
                     /locus_tag="KB927_000135"
     CDS             20042..20347
                     /locus_tag="KB927_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBB6839088.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(20428..21573)
                     /locus_tag="KB927_000136"
     CDS             complement(20428..21573)
                     /locus_tag="KB927_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6839089.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(21634..22281)
                     /locus_tag="KB927_000137"
     CDS             complement(21634..22281)
                     /locus_tag="KB927_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6839090.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            22475..22768
                     /locus_tag="KB927_000138"
     CDS             22475..22768
                     /locus_tag="KB927_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839091.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            22812..23123
                     /locus_tag="KB927_000139"
     CDS             22812..23123
                     /locus_tag="KB927_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839092.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            23120..23744
                     /locus_tag="KB927_000140"
                     /pseudo
     CDS             23120..23744
                     /locus_tag="KB927_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            23885..24043
                     /locus_tag="KB927_000141"
     CDS             23885..24043
                     /locus_tag="KB927_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839093.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            24044..24406
                     /locus_tag="KB927_000142"
     CDS             24044..24406
                     /locus_tag="KB927_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839094.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            24443..25291
                     /locus_tag="KB927_000143"
     CDS             24443..25291
                     /locus_tag="KB927_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBB6839095.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            25281..26756
                     /locus_tag="KB927_000144"
     CDS             25281..26756
                     /locus_tag="KB927_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBB6839096.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            27022..27429
                     /locus_tag="KB927_000145"
     CDS             27022..27429
                     /locus_tag="KB927_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBB6839097.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            27432..27647
                     /locus_tag="KB927_000146"
     CDS             27432..27647
                     /locus_tag="KB927_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839098.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            27651..28031
                     /locus_tag="KB927_000147"
     CDS             27651..28031
                     /locus_tag="KB927_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6839099.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            28165..28320
                     /locus_tag="KB927_000148"
     CDS             28165..28320
                     /locus_tag="KB927_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBB6839100.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            28389..28862
                     /locus_tag="KB927_000149"
     CDS             28389..28862
                     /locus_tag="KB927_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBB6839101.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            28859..30553
                     /locus_tag="KB927_000150"
     CDS             28859..30553
                     /locus_tag="KB927_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6839102.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            30519..30704
                     /locus_tag="KB927_000151"
     CDS             30519..30704
                     /locus_tag="KB927_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839103.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            30708..31883
                     /locus_tag="KB927_000152"
     CDS             30708..31883
                     /locus_tag="KB927_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6839104.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            31876..33399
                     /locus_tag="KB927_000153"
     CDS             31876..33399
                     /locus_tag="KB927_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6839105.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            33455..33739
                     /locus_tag="KB927_000154"
     CDS             33455..33739
                     /locus_tag="KB927_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBB6839106.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            33726..34061
                     /locus_tag="KB927_000155"
     CDS             33726..34061
                     /locus_tag="KB927_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBB6839107.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            34356..34982
                     /locus_tag="KB927_000156"
     CDS             34356..34982
                     /locus_tag="KB927_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839108.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            35724..36560
                     /locus_tag="KB927_000157"
     CDS             35724..36560
                     /locus_tag="KB927_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBB6839109.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            36625..37059
                     /locus_tag="KB927_000158"
     CDS             36625..37059
                     /locus_tag="KB927_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6839110.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(37127..38449)
                     /locus_tag="KB927_000159"
     CDS             complement(37127..38449)
                     /locus_tag="KB927_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBB6839111.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(38603..40243)
                     /locus_tag="KB927_000160"
     CDS             complement(38603..40243)
                     /locus_tag="KB927_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBB6839112.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            40573..41043
                     /locus_tag="KB927_000161"
     CDS             40573..41043
                     /locus_tag="KB927_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBB6839113.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            41672..42775
                     /locus_tag="KB927_000162"
     CDS             41672..42775
                     /locus_tag="KB927_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBB6839114.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            43059..43739
                     /locus_tag="KB927_000163"
     CDS             43059..43739
                     /locus_tag="KB927_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6839115.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            43829..44863
                     /locus_tag="KB927_000164"
     CDS             43829..44863
                     /locus_tag="KB927_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBB6839116.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            44877..45212
                     /locus_tag="KB927_000165"
     CDS             44877..45212
                     /locus_tag="KB927_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839117.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            45196..47676
                     /locus_tag="KB927_000166"
     CDS             45196..47676
                     /locus_tag="KB927_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839118.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            47732..49291
                     /locus_tag="KB927_000167"
     CDS             47732..49291
                     /locus_tag="KB927_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6839119.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            49288..50652
                     /locus_tag="KB927_000168"
     CDS             49288..50652
                     /locus_tag="KB927_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6839120.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            50823..51893
                     /locus_tag="KB927_000169"
     CDS             50823..51893
                     /locus_tag="KB927_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6839121.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            51908..52576
                     /locus_tag="KB927_000170"
     CDS             51908..52576
                     /locus_tag="KB927_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6839122.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            52596..53174
                     /locus_tag="KB927_000171"
     CDS             52596..53174
                     /locus_tag="KB927_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6839123.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            53577..54488
                     /locus_tag="KB927_000172"
     CDS             53577..54488
                     /locus_tag="KB927_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6839124.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(54744..55661)
                     /locus_tag="KB927_000173"
     CDS             complement(54744..55661)
                     /locus_tag="KB927_000173"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBB6839125.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            55863..56300
                     /gene="zapA"
                     /locus_tag="KB927_000174"
     CDS             55863..56300
                     /gene="zapA"
                     /locus_tag="KB927_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBB6839126.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            56358..56906
                     /locus_tag="KB927_000175"
     CDS             56358..56906
                     /locus_tag="KB927_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBB6839127.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            57021..59381
                     /locus_tag="KB927_000176"
     CDS             57021..59381
                     /locus_tag="KB927_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBB6839128.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            59468..59782
                     /gene="trxA"
                     /locus_tag="KB927_000177"
     CDS             59468..59782
                     /gene="trxA"
                     /locus_tag="KB927_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBB6839129.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            59964..61742
                     /gene="uvrC"
                     /locus_tag="KB927_000178"
     CDS             59964..61742
                     /gene="uvrC"
                     /locus_tag="KB927_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBB6839130.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREELPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            61887..62786
                     /locus_tag="KB927_000179"
     CDS             61887..62786
                     /locus_tag="KB927_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6839131.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            62779..64041
                     /locus_tag="KB927_000180"
     CDS             62779..64041
                     /locus_tag="KB927_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6839132.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            64202..66100
                     /locus_tag="KB927_000181"
     CDS             64202..66100
                     /locus_tag="KB927_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBB6839133.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(66399..67118)
                     /locus_tag="KB927_000182"
     CDS             complement(66399..67118)
                     /locus_tag="KB927_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBB6839134.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            67455..67787
                     /locus_tag="KB927_000183"
     CDS             67455..67787
                     /locus_tag="KB927_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839135.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            67774..69777
                     /locus_tag="KB927_000184"
     CDS             67774..69777
                     /locus_tag="KB927_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBB6839136.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            69796..70266
                     /locus_tag="KB927_000185"
     CDS             69796..70266
                     /locus_tag="KB927_000185"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBB6839137.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            70287..70871
                     /locus_tag="KB927_000186"
     CDS             70287..70871
                     /locus_tag="KB927_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBB6839138.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            70886..71872
                     /locus_tag="KB927_000187"
     CDS             70886..71872
                     /locus_tag="KB927_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBB6839139.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            71862..72173
                     /locus_tag="KB927_000188"
     CDS             71862..72173
                     /locus_tag="KB927_000188"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBB6839140.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            72195..73976
                     /locus_tag="KB927_000189"
     CDS             72195..73976
                     /locus_tag="KB927_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBB6839141.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            73969..75345
                     /locus_tag="KB927_000190"
     CDS             73969..75345
                     /locus_tag="KB927_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBB6839142.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            75352..75987
                     /locus_tag="KB927_000191"
     CDS             75352..75987
                     /locus_tag="KB927_000191"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBB6839143.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            76017..77372
                     /locus_tag="KB927_000192"
     CDS             76017..77372
                     /locus_tag="KB927_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBB6839144.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKITIHSKIALTVTGTLLLGGFVVFFFTERNGETLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(77564..78958)
                     /locus_tag="KB927_000193"
     CDS             complement(77564..78958)
                     /locus_tag="KB927_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBB6839145.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQKLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQNKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            79050..80021
                     /locus_tag="KB927_000194"
     CDS             79050..80021
                     /locus_tag="KB927_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBB6839146.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKDKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSATLTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            80018..80799
                     /locus_tag="KB927_000195"
                     /pseudo
     CDS             80018..80799
                     /locus_tag="KB927_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            complement(80968..81339)
                     /locus_tag="KB927_000196"
     CDS             complement(80968..81339)
                     /locus_tag="KB927_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6839147.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TTPSYYFVIDPDGYKIEVIRG"
     gene            81473..81916
                     /locus_tag="KB927_000197"
     CDS             81473..81916
                     /locus_tag="KB927_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBB6839148.1"
                     /translation="MDKPIFGEKKQSANYQTRYAAYIVIERDKRIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(81959..82768)
                     /gene="yidA"
                     /locus_tag="KB927_000198"
     CDS             complement(81959..82768)
                     /gene="yidA"
                     /locus_tag="KB927_000198"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBB6839149.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(82787..84154)
                     /locus_tag="KB927_000199"
     CDS             complement(82787..84154)
                     /locus_tag="KB927_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6839150.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHKVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(84138..84968)
                     /locus_tag="KB927_000200"
     CDS             complement(84138..84968)
                     /locus_tag="KB927_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBB6839151.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            85131..85568
                     /locus_tag="KB927_000201"
     CDS             85131..85568
                     /locus_tag="KB927_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBB6839152.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            85644..86264
                     /locus_tag="KB927_000202"
     CDS             85644..86264
                     /locus_tag="KB927_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBB6839153.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     EKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            86453..86959
                     /locus_tag="KB927_000203"
     CDS             86453..86959
                     /locus_tag="KB927_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBB6839154.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            86976..87875
                     /locus_tag="KB927_000204"
     CDS             86976..87875
                     /locus_tag="KB927_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBB6839155.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKARR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            87962..88847
                     /locus_tag="KB927_000205"
                     /pseudo
     CDS             87962..88847
                     /locus_tag="KB927_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
BASE COUNT        29420 a        15088 c        18400 g        26022 t
ORIGIN      
        1 tatttgtgtt actaattccg ttaatataca taagtgaaag cgttttatat aagaacttga
       61 aaagaaagaa gggatagaca tgaaaaaaag atacaaattg gtgatagctt tgctaaacat
      121 taccctatta ttcagcttaa gtgcatgtgg aaaaactaac gaagaagtaa cagcaaacat
      181 cgcagatcca atgataaaaa aagccactac attagaagta tatgtcgcaa acggcaaact
      241 gacaaactat gttgaaaatg ctgcaaaaat ctataaccgc aaaactggag caaatattga
      301 cttaaaaatt gtgaatgtag cttcgggaac agcaacagta caaatgatca ccccaaaatt
      361 ggtaacacac gaagatatgc cggatattat ctccatggca gacacttcag cagcaggtgt
      421 gctggaaaaa tttcaagatg ctttttatag tgctgatgaa tatggatttt atgacaaata
      481 tggcgatcag ttttatgatc aaaaattgaa tattttgcgt caacaaacga gtaatgaaac
      541 gattattcct tgggctagtg attttacccc agcactttgt tattatcaac caaaaaaatt
      601 tgctgaaata ggtgtagatt ttgaagaaat cagttcttgg gaagaatata tccaggtggc
      661 aaaagcatta aaagaaaaaa ctggtagttt tggaattgcc ttgccagaat ctggggacca
      721 agaattgttt atcaacatgc tagcccagca gaatcaatct ttgcttgatg aagaaggaaa
      781 tatccgtctg aatactaaag aagcgaaaca tgctgcaaag ttaatcaaag aaatgatcga
      841 ctcagatatt gtacatttct acggtgcaca agatgctgag aaagcatttc aagaatctgc
      901 aatgtttgtt gctggcggct ggtatgctac gaatatgtct ttgaattttc ctgatgcatc
      961 tgacaaatgg cgcatggctc cactgattcc tttttcaaaa gaaaatccag gaaaaggtgc
     1021 agtatcagga ggatcaagtt tttatgtccc taaagatgcc aaaaatccac aagtggcaca
     1081 acaatttctt acatttatgc tgacagatga agaatgctta gccaacgcac tggagctggg
     1141 cgtggctaca tctaactcat tggcctatca aacagaagca gctgagaaaa agtttgacta
     1201 ctaaggagga caaaaatact atgaactatt gaataaaatc aatgaaaata catcaaatac
     1261 tgttttacca gccacttatt cagatgctac gtcttatttg actaccgctg catataacta
     1321 ttggcaaaca ggtgattttg aaaattcata tctaaaagaa gcagaaaatt ttgctcataa
     1381 gtacggcgta aaattaactg gtgattaaaa aatattagga ggacttaacg atgatgcaat
     1441 cttcgttacc aagcaagaca ataaagaaca gcaagaaaaa agcaacagat acgtctcata
     1501 aaaaaagtgc ttatggattg gtcacacctt ttgttatttt ctttattgtg acgattttga
     1561 ttcccatcat tatctcgttt gcttttagtt ttatgaaaat tggctactca tttgaatttg
     1621 ttggatttga caattatcta gctatcttcc gagatccatt gtttattaaa tcttacacga
     1681 atgttttgat tatcatggca ggatcaattc caataacgat gctattagct atttactttg
     1741 ctgttttatt gaattcagca cagttaaaag gaaaaggatt ttttagaact gtctattata
     1801 ttccaaccat tacatcaacg gtggctgtag cttccgtatt catgactttt ttcaatccga
     1861 ctgggttatt caatggattt ttgaatgcgc taggaattaa cggtgtacag tggttaacaa
     1921 atcctttttg gatacgaata tcaatgatca tcacgatgat ttggcttagt gtaggatata
     1981 acactatttt atttttagct ggtcttcaag ggatttctaa agagatatac gaaagtgctg
     2041 aaatagatgg agcatcgaaa tttcggcaat tctttttatt aacgatcccc atgctaaagc
     2101 caatcatttt aatggccaca gttttagcca ctatcaatgg cttgggtaat ttcaatatcc
     2161 caaatatatt ctttgggact tccaatggac cagaaaattc agctttggtc gtaggagtca
     2221 atttatataa aacaagtttt gaaatggttg attttggaaa agcctctgct attgcctgga
     2281 cgatggtgtt tgtatctgtt atattatcgg ctattcaatt taaattcgga ggtgataaaa
     2341 atgactaaac aaaagataca aagcagaatt tttacgtacg tcattattgt gtttggtgcc
     2401 ttaatatttt tgatgccata tttatatatg attgtagctt caacgcaaag taatcaagaa
     2461 attttaagtg gcggaatcaa tttcaagttt ggggatatgc tattaaaaaa ctggcaagcc
     2521 atcatggcga gatataatta tcccttgatt atttggaatt cgattgttat tgctgtaatc
     2581 agtacagttt tagctacagc cagttctaca atggcgggtt atgcattagc aaagtatcgt
     2641 tttatgggga ataaactgtt gttcaataca gttatgctat ctaggatggt gccttttttt
     2701 accacattga ttcctttatt ttacattatg agtcgtttag gattatcgaa tacttatgca
     2761 ggtgtgatca tcccttcgat tgccagtaca acttcagtgt ttatgatgcg acaatatagc
     2821 agtcaatttc ctacagcact gatggaggct gccagaatcg atggtgccaa tgagtgggtg
     2881 atttttacga aaatcgctgt accgatttta tcacctacga ttattactag tggtttactt
     2941 atctttatgg gaagttggaa tcaatatcta tttccattag tcatgctttc agataaagat
     3001 aaatatacgg ttcccttaat tatcaaaaat atgacggttt ctagtacagg tgagccaatt
     3061 aattatggcg caattatgct aattttagca acttcagtga tcccaatggt cttgatttat
     3121 gtgtgggcgc agtctaaatt taaggagaat gacattggag ctgcaaataa gtaaaaaaaa
     3181 taacgaatgt taaccatcta gttcgttcta ggagcaactc cacattcata aaaattaaaa
     3241 gaatggcggg atatccatga atgaacagac gaaggaatgg tcaagaaaaa ttttgaatgt
     3301 agcttctgaa aagatagatg cggaattaga cagaatgggg aataaaattc catatatttc
     3361 ttacaacgga aaatatacag acgtaataaa ggacagagga atcgactggt ggaccaatgg
     3421 tttttggagt ggtattttat ggcagctctt tcacaagaca aaacgagaaa agttcaaaga
     3481 ggcagcaata caacaagaac aattattaga atctgccctg taccattttt cagacgttca
     3541 tcatgatgta ggttttttat tcttaccatc ggctattgca cattatcaac agtctcaaaa
     3601 caaacatagt cgacaactag ggttacatgc agctacggta cttgctggac gctataatat
     3661 ttcagggaac tatttagtag catggaatga ccataaacct ggttggatga ttattgatag
     3721 tatgatgaat ttaccattac tgtattgggc ttcgagggaa actggtgatc cgaggttctc
     3781 taaaattgct cggcagcatg cagatacaac agctaagtat ctagtgagga aagatggatc
     3841 aaccgggcat atcgcagaat ttgatgcaga atcagggaaa tatattcggt tacttggcgg
     3901 gcaaggatac aatgagaatt cttgttggag cagaggaaat gcatgggctt tatatggatt
     3961 cgcgttaagt tatcgttaca caaaaaatcc gtactatcta gctatagcag aaaagatagc
     4021 agtaaatttt attcagaaaa tcgaaaaaac tggttatatt cctctcattg attttgctgt
     4081 aaaagattcg aatattgata ccagtgctgg agtatgcgct gcatgcggtc ttctggaatt
     4141 agcaggatat gtttcctctg tacgatcaaa aatgtatcat gaagctgcta tcaatatact
     4201 ccaaaagaca gaaaagcact atgcaaattg gaatatggat gaagatggga tcattggagg
     4261 cggagcagaa gcataccata gagaactgac ttataatgtg ccactgatct attctgatta
     4321 tttttttatt gaaggcttac ttcgattaga acagtcggaa ttagctattt ggtagtaaaa
     4381 agaggagaaa atacaatgaa acatccagta ccactattaa ggaccagaca ggattacttt
     4441 gacttattta aaaagataaa tcaaccactc cagccgtttt atcgagcaag tggcgcacaa
     4501 attgattata tacatcaagg ggtaggatat ggaaataaaa ttgcaggaat ggaaggattc
     4561 tctcgggttt tatggggagc ggggcccgca attgaccaat tagatgaacg atggttgaaa
     4621 ttaattctat caggaataaa agctggaaca gatccttccc atcccgatta ttggggagaa
     4681 atacatgaaa gagaccagcg tatggtagaa atgcccgcaa tgttattagc gttatatcat
     4741 catgaacaat tattatggaa aaaattagat acaggagaaa aaagccagat tattcattgg
     4801 ttctcgcaaa tttttgaata tgaatgtgca gatggtaatt ggcaattttt taagataatt
     4861 gtcggaacaa ttatccaaaa atttggttat ccagttaaag aatcagcact gaaagaagca
     4921 tttgataata tagaaaattg ttatcttcaa aatggctggt atcgagacag ttcaagaggt
     4981 cgccaagatt attataatcc ttttgcattt cattattatg gtttgattta tagcgtacta
     5041 gaaccagaaa agcccattag ccagatatat aagaaccgag ctattgattt ttctagagac
     5101 tatattcatt tttttgcgga agatggtgca aatgtgcctt ttggtcgaag catgatttat
     5161 cgttttgcag tttcaagctt ttggtcagct atgttgtggg ccgatctttt gccttttaaa
     5221 ttaggtgaaa tcaaggggtt agtcaatcgg aatataagat ggtggatgca aaaagaaata
     5281 tttgatgaaa aaggtatcct gaatattggt tatacctacc ctcaattgac attgactgaa
     5341 ccctataata gtacgttatc tccattatgg ctgaataaga tttttttatt gttggcgcta
     5401 cctgaagacc atgagtattg gacggctaaa gaaatgccta tgcctattcg tgaaggaact
     5461 aaacttcttt cagaagccaa tttgctcata caacatgata atggacatac attttttttg
     5521 aatgcgggac aattagggcc aaatttccat acattgacca atgaaaaata tttaaaattt
     5581 gcttattcta gtcaatttgg tttttcgata ccgcgagcga atcaattgaa agcagaaatg
     5641 gcaatggatt caatgctagg gattcagcga gcggacacat atatcacgac cagttttaag
     5701 aatgagagca tcaaaaccta tggacagttc atcgttcgaa ataatgtacg agacattgta
     5761 tgtaagaaag aggtacttgc ctctacatgg gaacctactt tacaggcaaa aatcagaact
     5821 tggcttattc cttttgaagg ctggcagatt cgcgtacaca aagtagaatt agatacagaa
     5881 tatgttctat atgagacagg gtttgctatt gaatgttctc ctgagaaaga aggaataatc
     5941 atagaagaag acaaggaaaa ctatagggtg agtgaagctg gcttttcagg tattatctgt
     6001 ttaagtgacg atactattaa acgaaaatcc acagctatta tgggtttgcc caatacaaac
     6061 ttgatgacat gggaaaacac ttttattcct ggattagagg gtacatttgg aaaaggaacc
     6121 cattggctcg gaacaggagt ggttgctcat caagatcggg attatagttt agaagtatgg
     6181 aacaatcgtc ccaaaattga ttttgatggg acaaccgggc taactatcca aaataaaaac
     6241 aataaaaaaa gactaaaatt atgctaaagg ctggtgggga aatgcttgat aaagtgatgt
     6301 ttgaagagat aatacatcca gaaaaatgga taaatgaatg ttataaagaa ttaatggaaa
     6361 aagaatggaa taatgagatc gagcgttgtc gcagacacac ggagaggtta atcaaacgta
     6421 tcagtaacag tcagtatcaa ttcccaagcg agtgtcctat aaaaggacgt tatccattaa
     6481 gagacaatat tggttggaca gaaggatttt ggacaggaat taattggttg ttatttgaga
     6541 agacgggtga tcctttattt caacaaacag ctgaaaaagc agatatagat tttatccaca
     6601 ggattgactg tcaaattatc actaatcatc acgatcttgg ttttttgtat tctttatcaa
     6661 ccgtagcaga ttataaaata acgggaaatc gaaaaatgaa ggaagcttca attgatgctg
     6721 cagaaacatt acttcagcgt ttttgggaga aggcaggagt tatacaagct tggggagatc
     6781 ctagtgatcc ttcacaacaa ggtagaatga tcatggattg ttgcatgaat cttccattat
     6841 tgtattgggc gagtgaagaa actggaaatc aaaaatataa aaaagctgct caggctcata
     6901 ttcaaaatgc agcagattat ttagtaagag aagatggttc aacttatcat acattttata
     6961 tggatgtcaa agatggaaaa ccaagatatg gaagtacgca tcaaggttat agtgataatt
     7021 cctgttgggc tagaggccaa gcatggggga tttacggttt tgcattaagt tatcgttatt
     7081 tgaaagaaca aaaatatttt gatttaagca aaatattagc caattatttt atgaatcggt
     7141 tgccagaaga taccatttgt tattgggatt tgatctttga tgattctagc agagaagaaa
     7201 aagatacatc tagtatggtg atcatggttt gtggattatt agaattaata gaatcaggtc
     7261 tattagacaa aacagaaaag aacttatacc agtctgctgt ttggaaaatt atgcgacaat
     7321 tgaaagaaag atatgctaca acggaagaag aagatggctt tttaacacag tctgtttata
     7381 ataagcccaa aaataatggg gtaaatacac cttgtatttg gggtgattac tattatttag
     7441 aagctttagt gagaatgact agtaattggt cttcttattg gtgaaaaagg taaatatgga
     7501 atttttgttt gataaaataa aaaaagaaaa accaaaacag catgaatggt ttctgttttg
     7561 gttttttcgt taattttcat attcttctaa ttccaagctt agttcttccc attccgtcaa
     7621 ttttgtttct tgatcttgtc tagcagcttc taaatcttgg ttcagctcat tgagttttac
     7681 gtgatcttcc aggttttctg gcgcgaccat ttcttgttcc aactgatcga tccattcatc
     7741 gatccgcgcc atttcttctt caacctgagt aatttttcgt tgaaggctac ggataagctt
     7801 ttgctgttct ttgctttggt aataatcaga tttgttcgtg ggagcaggag cagattctgg
     7861 ctcatcttgt gccaacaatt cggcgatttc ttcttcttcc tgctttttct ctaaataata
     7921 atcatagtct cctagataga ctttgctgcc attttcagag agttcgacga cttttgtcgc
     7981 gatccgattg atgaaatatc ggtcatggga aacaaaaagc agtgtgccgt cataatcgat
     8041 caatgcattt tctaatactt ctttgttgtc aatatctaaa tggtttgttg gttcatccaa
     8101 aatcaaaaaa ttttctttgt tcatcgctaa cttggctaaa gcaacccgtg ctttttcacc
     8161 gccacttagc agagggattg gtttttctac atcttcgcca gaaaataaga aagcacctaa
     8221 agcacttcgg atctcttttt ctggagtggt aggatgctca tcccacaatt ctgctaggat
     8281 cgtcttgttt gtatgcagat cagcttgacc ttgatcgtaa tagccgatgg tgacatttgt
     8341 ccctagcgtt tcttttccac ggataaaagg gatctggtga atgattgatt tcagcaacgt
     8401 cgatttcccg ataccattcg gacctactag agcaatcgct tcttgacgac ggatatctag
     8461 attgattggt tcagataagg tgacattatc atatccgata gcggcatctt cgatttgcaa
     8521 gactacattt ccagaaggct tttctatact gaatagaaag tttgcttgtt tttcatcccc
     8581 ttgaggacga tccagccggt ccattttttc taatgtcttt ctgcggcttt gcgctcgttt
     8641 tgtggtagag gcgcgaacaa ggttccgagc aacgaagtct tctaatttat ggatttctgt
     8701 ttgctgcttt tcataagcct tccattcact tgctaactgt tctgctttca aatctagata
     8761 tttcgaatag ttacctttgt aatggcgcat ttttcttctg cttaattcat agacttcatt
     8821 gactacttta tctaaaaaat aacggtcatg ggaaacaatc aataatgcac cagtatagct
     8881 ttgcagataa ttctcaagcc aggaaagtgt ctcgatatct aaatggttcg ttggttcatc
     8941 tagaatcaaa atgtcagggt gttgcaaaag catgcgagct aaagctaaac gtgtgcgctg
     9001 tccgcctgat aaagtatcga ttttctgatc ataaaatgaa gaatcgaatt taaacccatg
     9061 caatacggaa cgaatttcat tttcataacc atagccgttt cgatctgaaa aatcgtgttg
     9121 cagccggtcg tattctttta aataagaact ataagcaggt gtgtctggcg taccttcgct
     9181 aatgaaaatc tctagctcgc gcatccgctc ttccatttgt ctaacttgtt caaaagcttt
     9241 cagcatctcg ttccaaactg tttcattgga atcaagtcct gtgtcctgag cgaggtatcc
     9301 gagagtcgct gttttatttt tagcgatctt tccttcatca ggtgcttcaa ttccagcaat
     9361 gatctttaat aaagtcgatt ttccagcgcc atttctgcca actaaagcga cacgagcgcc
     9421 tgtactgatt tctaaatgta tgttttcaaa taagacttct gcaccaaaat ggcgagcaat
     9481 ctgattggct tgtaataata tcatggaatc ctcttttcta ctttgtgaat tctcctcaaa
     9541 taaaaaacta tttttcaatt agtagtctac cataaattcc attatactgc gagatttgca
     9601 gaaatgataa ataaatgaat aaagaataaa atttcacaat atctgagcaa tggaattgat
     9661 tttttcctat aaatactgct atgatggaga aatcaaagat gtaattagac aatacgtgga
     9721 ggtcatttcg tgaaagatca tattattcca aaggcgacag ctaaaagact gcctttgtat
     9781 tatcgctatt taaggatttt aaataatgct ggaaagaaaa aagtgtcttc aactgaatta
     9841 agtgaagccg ttcaagtaga tagtgcaacg atccgtcgag atttttctta ttttggcgaa
     9901 ttaggaaaac gtgggtatgg ttatgatgta gaagatctta tgcacttttt tgcaaagaca
     9961 ttaaacgacg atcaattgac aaatgttgcg ctgatcggtg tagggaactt gggaagtgct
    10021 ttactaaaat acaaattcca tcaaagtaat agcatacgta tcagttgtgc ttttgatgtg
    10081 aatgaggaaa tcgttgggcg catcgtagac ggtatccccg tttatccaat ggaagatatg
    10141 tcagaacaaa tcaagatcca acaaatcgaa gtagcaattt taacgatacc cgctgaaaga
    10201 gcacaagaag tagtcaatca gttaacggaa gcaggaatca aaggaatctt gaactttacc
    10261 gctgctcgat tgaatgctcc gtcagatgta ttgatccaaa atgttgattt gacgaatgaa
    10321 ttgcaaacct tgatctattt cttgcattct gacgcaaatg cgcattccga aaatacagca
    10381 gaataaaaat aaaaagcgat tgaacaaatg aaggcaaaac tttcacttgt tcaatcgctt
    10441 ttttctgttt ggacaacgat tattttgttc ggaagatttc ttcataagaa agggaatcat
    10501 cttctgctgt cagttcatct agtagataac ggattttttt aaagtcgatg aaccgtgctt
    10561 gccgaaagac ttcttttcct tgatgaaaaa tcaggacaac tggcgcagtc agcacttcaa
    10621 atttactagc tacttctggt gtttcaaatg catccaaatg aagtgccgga atatcataat
    10681 gtgtgagaag ttcctctagt cgtggacgaa cagcgtgaca aacactgcaa ttaggcatcg
    10741 aaagataaat gacggcaacg gatgactgtt gcagtatgtc ttgaacttca gtcaagttag
    10801 tggtttgttt catttttatt ctccctttta tgatagaagt gatatgtatg agaccttaat
    10861 ttaatgggaa taacagaaaa agtcaattga agtgctttgg taaaaaataa gagttgtgta
    10921 aaaatttaca gagcaacttg ttttttttga ataaaagcgt atatttgcaa agcgaatgaa
    10981 ctagaaataa aaaggaggaa actcatgttt tcttttattc caaattcggt tttgcagatg
    11041 agtacgattt tcttatcgat cgttattgaa gcattacctt tcgtattatt aggctgtctt
    11101 atctcaggcg ccttacaagt atttttgacc ccagaacgtg tgaagagatg gcttcctgaa
    11161 aatcgtatct tctctatttt tactggttcg atcttaggat ttttctttcc ttcatgtgaa
    11221 tgcggcatcg taccgatcgt tcatcaattt gttaaaaaag gcgtaccagt tcacacagcg
    11281 tttgctttta tgctgactgc tccgatcatc aatccaatcg tgattttttc cacttttatc
    11341 gcatttggca attcttggca gatggcaagc tggcgggtga taggcagctt ttttgttgcc
    11401 cttgtgattg gtgtctggct tgcctatttt caaaaagacg ctgtattgaa agaaaaaatc
    11461 acgtctaaag tagcagaaaa tcaccatcat catgtccatg aagaagaaca aagtgagaag
    11521 aatgaaccaa aaaatcagct gatccatcaa actgggcatg tgttgacaca ttcaatcgac
    11581 gaattttttg atacaggtcg ttatttgatc attggcggat taatcgcagc tgcgatgcag
    11641 acttatttac caactagaat tatgctaacg ctcggctcaa caaagatttt agccattatc
    11701 atcatgctgt tattggcctt tacgatgtct ctttgctcag aagcagatgc gtttatagga
    11761 tcttctttgt taagtctgtt cggcacagca cctgtagctg cctttttggt ctttggccca
    11821 atggtcgata tcaaaaatct actgatgatg aaacgatatt ttacaggacg ctttatttta
    11881 tcgctgatcg gactgattgc ccttagcgtt attggattca cattatttat ttaggaggga
    11941 aaatatgctg cggtttttga ttttatctgg gtatttcgaa ttgatgatgt acttgcaagt
    12001 ttctggcaaa ctcgatcaat atatcaatgt ccattatcgc tacttagcta ttctttcaat
    12061 gattttatct gctcttttgg ctttagttca gctgtatttg tgggtcaaaa acggaaaagc
    12121 agaagaaaag gcacacgagc acgatcatga ccatgggttg tcaaaacctt atcaacgtgg
    12181 aatcgcttat gtactgctag ctttgccagt aatcgtgggg acgttgtttc caacagttag
    12241 tctcgacact acgatcgtag aagccaaagg atttaatttc ccagtaagta aagaatcagt
    12301 aggggatccg gagatgcaga cacaatactt aaagccggat accagtattt atttcaacaa
    12361 atcagactac ttagaccaaa tgaatgagtt gaaagaaaag tatggggata agcaaactat
    12421 caagatcaca gatgaaaact atttagaagt tatggagcta atttataatt accctagcga
    12481 attcattggc aaaaaaatca gctatgaagg atttgtttac caaacaccga acgatagcaa
    12541 tacagatatc ttcttgttcc gattcggcat tatccattgt gtggcagatt caggagtctt
    12601 tggtttgttg acgcatatgc cggaaggagt aacggttaaa aatgatgaat ggtataaaat
    12661 agaaggaacc atccaatcag actattatca accattcaag cgtgaaatcc catctgtagt
    12721 tgttacaaac gctgagaaag tctctgctcc gaaaaatcag tatgtgtatc gttcttttta
    12781 aaagaacaaa ataaataaac atagctcaga cagctgacac gcaaggacgt cggttgtctg
    12841 gctttttttg catgatgtat tcatttgttt gatatttatt ttagaagcag catcctgaaa
    12901 gtatttgata tcggtttcaa aggtgttgga aaagattgtg aagagaatta caatttattc
    12961 ctaacatgta tgttgaaaag ttgtatgaaa tgattttgat agtaaaatat cgagtggagg
    13021 tactttttat ggtaacgcgt atatttattt tggatgatag tttggttttt gaaaaaatgc
    13081 tagtagaaat tttggaagaa tccagaattt tattaagtcc ttggaaattt gagatcgttc
    13141 agggattgaa cgttatacaa tttgttgaat tcattaaaaa taatgaaatc tattcctcag
    13201 atattttttt cctagacatc gatttgaacg cctattatag cggtatcgaa ctaggcgaaa
    13261 tgcttagaga aaagaatgaa aagtgtaaaa ttgtttatct aacgtctcat ccgaataaag
    13321 caataactgt tattaatcga aagattacgc ctagtggtta tttgataaaa gaattcactt
    13381 atgaaaaaaa taaaaaaagc atccaaagtt acttattgaa agaaaaagaa aactatcctg
    13441 ttcaacatgc tacgaaaaaa aggtggacaa ctgtccgtta tggtaatagc gatcactata
    13501 tccattacga tgaaatcctt tatctaatga gcatgccagg ttataaaaat aaaataggcc
    13561 tagtattgaa agatgaagag attctcgtaa acggcacaat taaaaaatat aaaaaatcac
    13621 tcgaatatga gtatttatgt aaagatttaa aagcttatat cattaatact gaaaacatta
    13681 catctattag cagagtaaac gaaatagtaa catttgcaaa tggagaacaa ctagagatgg
    13741 gaaagagaag tattgataaa ctaaagaatt ttatgcaaga aaagatagaa aatgaatcat
    13801 tttaaagaaa acaaagactc atatcttacc tgttagaaga gtgttttcct gtagaagaga
    13861 acaacccaag tagcagccta gtcgtttcta tccttttttg ttatgcactc tttttgacat
    13921 ttactccacc aataacgaag ggtacaataa aaagtaataa caaacaaaag gagtacagaa
    13981 atgattgaat tcatcaatgt aagtaaaagt tacgggaaaa aacaagcatt aaaagacttg
    14041 tctctctcga taagacaagg ggaaattttt ggatttttag gacataatgg tgccggaaaa
    14101 tcaactacga ttaaaagttt agttagtatt attgaaccat catcgggaac gattttagta
    14161 gatggaatga aattgacgga aaatcgattg agtatcaaac aaaaaatcgg ttatgtgcct
    14221 gattccccag atattttttt acaattgacg gctggagaat attgggactt gatttcagct
    14281 gcctatgaat tagacacaca aaaaaaagaa aagcgtttag cagaattgac agcgcttttt
    14341 gatatgtata gtcatcaaaa tgaaacaatc gcaagttttt cacatggaat gcgtcaaaaa
    14401 acgattttga tcggcacgtt gctgccagat ccagatattt gggtattgga tgaacctttg
    14461 caaggacttg atcctcaagc agcatttgat ttgaaagaaa tgatgaaggc tcatgccgca
    14521 aaaggaaaaa cagtcatttt ttctacacat gtattggata ccgcacaaca gttatgcgat
    14581 aaactggcta ttttgaagaa aggtgaattg atttatcagg gggcagttag tgaattattg
    14641 aatggctcac ctgatgaaac gctagaaaag atttatttga aaatggctgg aaggcaagcg
    14701 acaggagatg gaccgtatgt ataagcgaca attattagaa ttaattcgag ttaatctttt
    14761 atatgttaat ccacagctca cgaataaagc aagagagaaa ggaaaaaagg gaaagcgatt
    14821 aactatctat cttttgtctc aaaatctttt ttcagggctg atttttttac tgatttacgg
    14881 atttgctatg tttgctatga actttgttaa attgccaggt ttctttactt attacgtggc
    14941 actttttggt atgttaggtt taactcaaag tatatcagtc atttataata tcttttttga
    15001 aggaaatgac ctgcaagtat ttttgcctct gccttttgga caagaacagg ttttttcagc
    15061 aaagattttg gtagttgctt tgaccatcat tccttttgtt tttccgcttc tagtcatgtt
    15121 tattttaacc ggatggcgag ctgatctagg gattttgctt actatcatta tctcaatcct
    15181 tttgttttct ctatttttga ttattctttt ttgtctggct agtttgattg tttttggttt
    15241 ggctcgaaca gcagtgttta aaaaacatag aaaaacagtt tctagtatct tgcttggcag
    15301 ctcgatgctg atcgcatttg ctggaatcat gtggatgaat catcaaacgg ggactattga
    15361 aaatgagtta acagatcggc atccgatttc gatattattg ccattctatg atgctgccag
    15421 tcagccactt tctcaacaag gtttattggg ttggggaata ctagctatca cggctctggg
    15481 atttttcctt gctgtaaaac agctgatagt accaaagctt acagagcaac tgactgattc
    15541 aaacagtgag ttcaaaataa aaagaaccca taaaaagaac caaaatgtgc atcagctttt
    15601 atttagttac aatgctcaat tagtaaaaga acctaatttg attatgcaag ttctttcttc
    15661 ttccttgtta actccaatca tttttattct tgcttttgcc ctaggaggcg aaataaaatt
    15721 aactgattta gataataagt taatcggtgt tgttttcctg gtagggatcg cattggcttt
    15781 cttaacagtt aatcagactt cttttatcag caatcttatt tctttggatc aagaaaattt
    15841 tctgtttatc cgttctttgc caatctctat gaaccaatat ttaaaagaaa agttcagatt
    15901 cggatggata ttgcagagtt ttttaactgg tgggatcgca ttattaagcg gactgtcttt
    15961 tcagctgcct ttgtttttta tccctagctt gctatttggt tctttattcg gctgctactt
    16021 attgtcacta cgttatttcg ctagagatta tcggttgctg ctgctgaact ggaccaatat
    16081 taaccaatta tttaacagag gttcaggaag tttgggttta gtcgcaacta tgatgggttc
    16141 attgatcatc agtattattc ttatcgtctt atacggaatg ttggctttgt tttatccatt
    16201 ttggttagtg aatattcctg tgatcggttt agttctaata ctttccgctc tatggatcgt
    16261 ttattatcaa cgaacgtttt ggaaaaaatt tgaataaaga agaggggccg tgacaaaaat
    16321 catgtcgcag cccctttttt acagatagag ggtgttcaaa agtcagtttc tcagtattaa
    16381 gtcaatttta tgtaaaaatg tgagaagcta tttttacaaa acttttttta atactcataa
    16441 ttacttctta ttgctcctgc ggttacttgt cgcaatgttt gtgagatatt ttgtcatcgc
    16501 tcaaggctga acgtctcttt cacaaccttt tctttgttac acttcgttta tttaaaaagc
    16561 cgtttttttc gtttcatcat gattgcgtca cgctttactt tgaaattacg gatgttatgg
    16621 ttaaagactt ctgataatac aagacctaaa gcgattgctc cagcaatcat aattgcttgg
    16681 accgcataat gagccgcttc tcgataggat tcagtaacga gatttcgaac cgcttgataa
    16741 gctaaaccac cagggactag aggaaccatc ccgggaatat tgaaaatcgt tacgggcatt
    16801 ttcaaacgtt tagagaaaag atcgctgatg aatgctactc ctaaagaacc aagcaatgaa
    16861 ccaaaagcag cagatccgcc tatttgaaca cagatccagt agatcatcca gccaaaagca
    16921 ccagaaagac cacaacaaat caatgaacgc ctaggtacat ttgtaataac ggcaaatgcc
    16981 gcagtcgcta aaaaactaaa agaaaactga ataaatatcg tccccatact tgtgttcctt
    17041 tcctaataaa aaagctggaa aataaaagca atcgcaaaac cgatcatcgt agcagtcatc
    17101 atcgcttctg ttccgcgaga aactcctgag acataatgtc cagctagcaa atcacggata
    17161 gcgttcgtaa tttgaactcc aggaactaaa ggcatcacac atccgataat gattagatcc
    17221 tgattgcttc ctaagccaaa acgtacgctg tagatagcgg ctatgccaat caataaagaa
    17281 gataaaaatt ccgataaaaa tttgattcta aaaaatttca aactatatag ataagctgcg
    17341 tatcccaatc ctccaatgac taaagtcaca ggtaaatcgg tcatctttcc gccaaataac
    17401 accataattg ttccactgat cactgccgcg ctaacgattt gcaaccagac aggaaagaaa
    17461 gaacggtctc ggtcgattgc ttgcagttcg cagtaaagtt cttctaatgt tagctctgaa
    17521 gcaacatatt tacgtgaaag atcatttact tttactactt tttctaaatt aatcgaacgg
    17581 ttggtaattt gttccattcg gatggtcgag gtacgatcaa gaccaataaa gagaccggtt
    17641 tgagtgacat agctgaccaa acggaaattt ccagaagcta aagcaattcg actcatcgta
    17701 tcttctaccc gatacatctc cgcattgctt tccatcatga ttttcccagc gagtaaacaa
    17761 gtgtccagca acagatctaa ttcttttccc gtcatagcat cttctccaat aattgattga
    17821 ttagttttat tttactacaa aacataccag aagcgtaaag aataaaaaaa cttgaggaag
    17881 gaataaaaga ggcgtatact gtttttgtat tgcgggtgta gtttagtggt aaaatcccag
    17941 cttcccaagc tgatgtcgcg ggttcgattc ccgtcacccg cttaaaatag gttgtgaaaa
    18001 agctgctctg caacaagtaa taagaacagc caagcaaaaa caacttctta tgtttttaac
    18061 ttggatggac ttattaccgc agatgcaagc ttttgcgcac cgtttaccaa gcggttgtga
    18121 aatcagtgta ttgtcttgag tatgaagaaa atttttgaat aataataaat accttacaga
    18181 tagagtggtg actgattaga gacgaggaat ccgtctcttt tttgtatttt taagccatct
    18241 taaaacaggt tttatttttt gctgtttcta tttctttcta gtatttattt ataggggaac
    18301 atatgttaag atttagggag ctgttagtaa aggagtaaag aaatgagcaa aaaaacaacc
    18361 aaggcgatcg tggggatcgt cgctgctgtg attgcagggg cattcggtgt ttccaccaca
    18421 caaaaagatt cagatatctt tcagcagatt acaactattt ttgattccac accacaagct
    18481 tctcaagtag cggatgtgcc agaatatgat ggaaaacatc aagaaataga aatcaatggg
    18541 aatcagccgg aatttacaaa agaggatctt agcctttcca aaggaacatg ggaaagctat
    18601 tcaaatattg ataaattgaa cagagtagga caagccaatg ctatgcttgg aaaagatttg
    18661 ttccctactg aaaagagaga gcctttgtat attgacccga caggttggaa acaaaagaaa
    18721 ttaagtgacg ggcaatggtt atataatcgc agccatttaa ttggtttcca gctgactggt
    18781 caaaataaca acattaaaaa cttgatgaca gggacacgtt cgttgaatgc tccatacatg
    18841 cttgctcacg aaaatgatat tgcggcatat atcaaagaaa caaatcatca tgtacgctac
    18901 cgtgtcactc ctcattttga ggggaatgaa ctggtagcca ggggagtgca attggaagca
    18961 gaaagcattg aagacaaaaa aattgaattc aatgtcttta tctacaatgt tcaagatggc
    19021 tacacgatca attatgagac aggacaagca acaaaaacaa aaaattagta gcagctattc
    19081 gaatttttta tgaatattat gaaaaaattg tgtaaaaaca tacattcaaa gaaatatagc
    19141 gtatacttta tgaaaagagt acttttgata aagctacaga aaaaaggaaa aaaacataca
    19201 aatagtgttt cttaatttat tcggaagttt ggaatatttg tttgtagttt tccctttctt
    19261 cgagtaaaat aaggttgtag aaggtaagct ggaattacct tgcgggaaag aggtgtagaa
    19321 tcatgggttt tacagatgaa accgtacgtt ttggttttga cgatagtcgc aaaaaagaag
    19381 tgagcgaaac attagcgatt gtttatcggg ctttggaaga aaaaggctac aatccaatca
    19441 atcagattgt cggctacttg ctttctggag acccggccta cattcctcgt tatcgtgatg
    19501 ctcgaaattt gattcgccgt cacgaacgcg atgagatcat ggaagtaatt gtcaaggact
    19561 acctctcaaa tcatggagtg aatttatgag agtaatgggc ttggatgtcg gttctaagac
    19621 agtaggtgtt gctatcagtg acccctttgg ctggacagct caaggagtag agatcattcg
    19681 gatcaatgaa gcagaagaag agtttggctt tgatcggttg aaggaattag tagcacaata
    19741 tgaagtagac cggtttgtag ttggattacc taaaaatatg aacaattcca tcggaccaag
    19801 ggcagaagct tccatgtcat acggagaaaa gatcaaagaa ctattctcct tgccagttga
    19861 ttatcaagat gaacgattaa ccactgttca ggcagaacgt atgctagtag agcaggcaaa
    19921 tacttcaaga gccaaacgaa aaaaagtcat cgataaatta gcagctgtga tgatcttaca
    19981 aaattattta gacggctcag gtaagcaatt attttaataa taaaagaaaa gaggtaatct
    20041 tatgacagaa cataaccatt cccacgacca tgaaggacac gaacacatca cattggtgga
    20101 tgaccaagga aatgaaacat tatatgaaat cctactaaca gttgacggac aagaagaatt
    20161 tggacgtaac tatgttcttt tatatcctgc tggtgtttca gaagatgaag atgtagaatt
    20221 acaagcttat gcatacatcg aaaacgaaga tggaacagaa ggcgagttag aacaaatcga
    20281 aacagacgca gaatgggaca tgattgaaga agtattcaat acattcatgg cggaagaaga
    20341 agaatagact ataaagctag gagaaacctt gatatgatag ggtttctcct ttttttattt
    20401 tttactgtat gccatattgt atgccatcta gtcaatattt aagtgttgta ctaatttttc
    20461 aacagtcttt tctttcgttt cttttgccaa gtgaccgtaa caatcgatcg tctgactaat
    20521 ttttgtatgc cgtaatctag tttgaacttc taccatagta gctccagcgt ccaagagcat
    20581 tgaagcatga gtgtgtcttg ctacatgcac accgagaaat ggaaccatag ctttttcaca
    20641 aatagtaatc aatcttgcat aaatagcgtg gtgtgtgatt agttctttat agataccaca
    20701 aaaaatcata gtcggatcag ttacaccaag tgtcagcata tatttccgct gattaatctg
    20761 ccattttttt aatatagaaa ttgttctttc atctagtgga agaaccccag cactacaatc
    20821 agttttagga tcactgattt tatagccatt tttggattgg cttagtgttt tattgatggt
    20881 gaccgtattt tcttgaaaat caatgtctga ccaattcaat gcaagggctt cactgatcct
    20941 aaccccgcta taaaagagaa agcgtagtaa cgttttatca aagtcgtttc gataagtttc
    21001 aggtttgctg tttaggtaat caaacaaggt gatcagttgt tctttactgt aaactttgac
    21061 cttttcttta tgcttagtgg tggttctttt aggcattaat acgttgtcta gtggattagt
    21121 ctcaataatc ccaagattga tagcgtagct aaaaatacgc ttagaagttg aatgaagtac
    21181 cttgtattgg tcagtagttt cagcccagct atttacaatt tgttgggctt tttttaccgt
    21241 gacttcattc acacgaagat ttccatattt tggaagaatc cactttctaa acttgatttc
    21301 agttttcatg aaggtggctt ctcggacagt ggttttatat gtttctagcc acaagtcata
    21361 aacttcttta aacgtttcgt tgttcgcttt tttaataccg tttttatcgt agtccacttg
    21421 caagcgtgac aaggcaagct gggcttcttt ttttgttttg taacctcgtc tacgaacctt
    21481 atcaggtttg ccagtcattt tgttcattcc aagataggct tcatagagcc aaaatttacc
    21541 ttttttagtt tcatattgct tgaatgttgc cataatagtt ttccctccat agtgtagcaa
    21601 gccgtggggg cggttggagg aggcagttta ttattatttt gaatagtgtt tatttagctc
    21661 agtaacaaga gctgtgaact cttttagaag atcattttca taaaattctt gatactcttt
    21721 tttctcatct gtattttttt ctgaatcatt aattaatgag tcatatcgta aaagcgtatt
    21781 tagaagagct gcgagataag caattggggt actcccgtca ggaaattcaa ttcgagatcc
    21841 tgttttaaga tattttattg cgtttgttaa ataaatcttc tgtgagacag tcaggttatc
    21901 ttcttcgatg ttattgatag cattagaaag attagaatca attatagagt tatttttttc
    21961 aatagttttt ttcaattgct tttcaagcac atttcgctta atttcgggca tcatatgcat
    22021 atctcttaat gtataagatc cgtttaatag ataggtagtg gatacatcta atacctttga
    22081 aagttgttta agcctggtgt tattgggaag attatagcca ttttcccaat tactaacggc
    22141 acctttactg gccggtgggg ataatttacc tccaagttgt tccattgaga gtcccttttc
    22201 aattctagcc agtctaattc tttgtcctgt ctccactgct tcggggtatt tttttctagc
    22261 cacattttca ccaccattca tatattttct ctactatatc acgatttaaa tatgtgtgaa
    22321 acataaaagt tcaaaaaagt atgttaaaat tcttgcaaat gaaaaggtat gatggtatat
    22381 tgagtttata agaggtatag aaatgtattc aagagcctct tgcatttttt taaaatcttt
    22441 gtatagaaat gtatgctaac gaggggggat aaatatggaa ttaaaaattg acaaactcac
    22501 gcttgatgat ccagctttta aaattattga cgatcgagtt gttcaacaag tagagcaaac
    22561 tcaaggaacg ttactttcat tattagaaaa aaagtaccag tttccaaaat atatgaacaa
    22621 ggcacaagct gctaagtata tgaacgtttc atacaatact atgatgcaga aatatgttcc
    22681 taacggttta aagttgatta tagttgatgg agtcgtaaga atttcacaag atgaatgtga
    22741 tcgctttatg gaagaatacc aaaaataaac gcaagccgtg ggggcaaagg gattaatagg
    22801 aggaaataat aatggaatcg acacaaaata aagcaatcga aaaagtatta tcaacaattc
    22861 ttacagaaga cacagcggca gaattagcaa acttggaagg caaagcgcta gaagaaacgt
    22921 ttgaatgttt gtacgaacaa atggactatc aaaaattgct accacaagaa ccaacggtaa
    22981 gcggagtatt gcgtggcttg aacgatttag tacaagcaga gtttaaagaa cgactttcta
    23041 ttgaagagta tcaagaaatt ttgtatcagc aagttgagtt gttagcgagc ttgctagggc
    23101 ttgaactgga ggacgttgaa tgaaaactga aatttggaac ggacacatta taagatttgt
    23161 cgatattaat gatgaatggt gggcagtggc gaaagatgtt gcggaagcgt taggtcttaa
    23221 acaggttact agagccattc actctttgcc taaagatggg gttactacta gtaaggtcat
    23281 cgattcattg ggcagaacac aagatgtaaa catcatcaac gaaaaaaaat atttaccgca
    23341 tggcattcaa aagccgtaaa aaagaagccg aggcatttca agactggatt ttcgacatca
    23401 tcaaagaact acgccagtcc acaggacttg aaggctttca agtattccgc atgctagaca
    23461 aagaacacca aaaagaagca atgactaaat taagccacgc tattactgaa ccaaaaccag
    23521 tagactacat taaagcgaat gtgatagcca ataaagctgt atcaactatt tatggtcatt
    23581 ccaaaatggt aaaaaagaaa gatatgactc ctgaaatgtt ggttgatcgt gaacctattt
    23641 tagatgagac agtagaatta atgactgtta aagaaaaata tgggttgcag ttttcagtga
    23701 gtgagaaaat ttataatcgt tctgctgaat tgcagacaac ttaggagcat taacatgatc
    23761 gagaacaaag aaaaagcctt atccataaca gtcttggcgg acaggataaa ggcaacttaa
    23821 ttgggataaa acccgatatt ctttgttccg attataccat attaaaaaat cggagggaac
    23881 cattatgaaa cgaaacttaa ttataggaag cattttaatc ggcggaattt tcggcttatt
    23941 accattaatt gcaaaaatag ctatctttgc aggattagcg ttatatctct tcactgctta
    24001 tgacgagtac gactatcaat taagaactgg agggcataag tagatgtaca aaacaaaact
    24061 attaaaccaa ctcgatagcc ttgaattaga ggaaattaat caagggatcg ctgaactaga
    24121 aaataatatc gggaaaacct actttggaaa ttcattcaat gaaaaactaa cagttttgta
    24181 tgtactcaaa aaacatgcag aacacaaaat aatttgtcga gaaatcaacg agctaaaaaa
    24241 tcagatttta accgcatggt taaacattac tgatatgcaa gaagcaaggg tgaaaacatt
    24301 taatacatgg gtaaagtatc agaatcaatt aaaaggtgct gaatttgttc gggatgggtt
    24361 gaaatacgaa cttgagcagt tgaagctcat ggaggtgtct gaatgattta taccagtatt
    24421 ttgaaaaagg aggagaggtt tattggcaaa taattatcaa gcagcaacgg aattacaaaa
    24481 gtcgggatgg tcaatttatc ccttatctcc tggaactaaa attccaataa aaggctctag
    24541 tggttggaat gatgcaacta acgattctaa tcaaattaat gaatggtgga cggaagatgc
    24601 aactagaaat attgggttaa tgcttgaaga tcatcaaatg gtggtagttg acctagatca
    24661 acattctgaa acacgaaacg gcgttgagaa ttataaaaaa cttgcttcaa tgtatgatcc
    24721 atttccttct acttatacgg aaatcacacc aggtaaagga atccatttct tctttaaaat
    24781 tcctgatggt gtaattatcc aacaagaaac aggtgcattt gctgatatct tcgggcgtga
    24841 tgataaaggt aaaagtttaa gcgggattga tattatcact aaaggagttc caatagcgcc
    24901 aactatgatt atttcaagaa gtgttgggag agcatatgaa cctattgaaa acgtatctct
    24961 aaataatatt gcaccagctc ccgattggct agtgaaccta ctgctaaaaa aaccgcaaga
    25021 aataaagact caataccgac ccgtagcaaa aacagggaca gcaaaaaaat tagatatgat
    25081 tgttcaaggc gctggcgaag gtagtagaaa cgatcattta actaagttat gcggttggtt
    25141 actatggcac ggtgtagata atcaaacttt agcagaattg atttatacag caaatgcgta
    25201 caatgaacca ccgctaaaag ataaagaagt gaatcaaatt attcgatcga tgattaaaaa
    25261 agatttgagg gggaaagctc atggctcata agcataaatt agatagtatt ttagactttc
    25321 ccgaagccag cgagcgtgaa gacaatatca ttgaattgaa aacctggatg tcacgattaa
    25381 gatgcaataa agacgatcag attaaaagta acagtgttgt gaatgcagaa ttgattttaa
    25441 ccaatgatag caatttagct ggaacaattg cttataacga atttagcgga tacattcacc
    25501 tattaaaaga ttctccttgg atcaatcgta ccgctggaga atgggaagac agttttgagg
    25561 atgccttaac ggcatatatt gaagaaaact acaatgtagt ttttgatgac aacaaaatac
    25621 acaaagcagt agtaaatgtg gctagaaaga atgttttcaa cccagtaaaa gaacgtatcg
    25681 aaaaagttaa atgggatcaa cagcctagac tggaaacact gtttattgac cttttagggg
    25741 tagacgacaa cctttacaca cgagaagtaa caaaacgttg gatagtcgga tcagtcgcac
    25801 gtatctataa accaggaata aagtttgaga tcgttccagt tttggatgga ccgcaaggga
    25861 ttggtaagag taccgttcca gcattacttt acacggatga ttttttcacc gattcattag
    25921 attcgctagg tgaaaagaaa gatgattata tgcagcttca aggcaatgta attattgaac
    25981 ttggagaatt atcttcaatg aacaaaacta aaattgaaca gataaaaaac ttcatcagtg
    26041 ccaagatcga taaaattaga cctccttatg gtcggaatgt catagcttgg gcaaggcaat
    26101 gtgtatttat tggaacgtcg aatgatgggc agtatttgaa agatgataca ggaaaccgcc
    26161 gtttttatcc tttgccttgt aagaataagc caaagatgaa tccgtttaaa acaaaggatg
    26221 aatattttct tcaagtgtta gctgaagcaa aggtgctttt tgataaagga caacgaatct
    26281 attttagtcc cgatgaagat aaagaagtct tagaaattgc aaaagactat caagaggatg
    26341 ccaagatgga gaatccaatt aaagaagcaa tcactaaata tttggaaatg gaaatcccgt
    26401 ataaatggga agaagctcca gcgtgggcga gacgttctta ttatcagaac tatcctgaca
    26461 gtaaatgtaa tgagaaaaat ttacagcatt tctataatgg agctactatg caacaagagt
    26521 tttatttagt tgatagcgta ctcaccgctg atattttgga agctgttttt gataaacaag
    26581 caaaggattt attgaatggt cgatcagatg cagaaactaa aaagattgcc ttgattatta
    26641 gcagtattcc tggttgggaa cggaagcaac tgccaaaaag aaataaacga cgaggatttt
    26701 acaataagtc aaatgcctat gaaaataaaa atcgagctgg aaagtacaaa aagtaacggg
    26761 tagtaacggg tcagtaacac ctagcccgtt actagtttac ccttactgcc ccaagggata
    26821 cagcaatttg gtaacggggt aacaccttat ttccttaaaa cttttgaaat agttagctaa
    26881 tatgctgggg aataatgtta ctggatttta cccgttacct gttaccaaaa cgctagaacc
    26941 cttgtccccg ttgggattga gtggtaacgg gtacctgtta cgtaggtgtt accacgtgtt
    27001 acgaatcaag gaggaaagta aatgctcaat attatttcaa caaacaaagc accgaacttt
    27061 caatatacag atgaaatgga tcggtttcta atgaacacgc tggcatttag tgtgggattg
    27121 gtaacagaag attattccac atttgatcca gaagtattaa agataatgga agaagaacct
    27181 gattggctgc aggagtcagt agcgtggtgt caatcgctag tagtgggatc attggtagat
    27241 agtggcaact atgatgatac aggtgagcta atggatgaat ttaattgtct gcttaaccta
    27301 tatgatcgag cgagacaacg agagcttaca tcgaatgagg ataatttgtt tttaaacatc
    27361 catgataagt tcttggcttt gctactaaca gatgatgaat tgataactaa tttattggag
    27421 gtagaataat tatgcatatg gaaagtatta gatacttcga tggtgagaaa cacattgagt
    27481 attcaaacac tcaagaagat gtagacttta ttagttttga ggaagataaa atcactaaag
    27541 ttaattttaa agacggaacg tgcttgaaga tagtttcgcc ttatattgaa tacaaatcaa
    27601 aatgggaaca agatgattct gacgaacgag atcgctttgg ttggtaatct atggcagtta
    27661 aaaaacaatg taatcatgct ggatgtaaaa cattgattga ttataggcag aagtattgtg
    27721 ggaagcataa agcaaagcaa acggcaatta agcgtgaaga aagaaagcaa agcgaaggta
    27781 aatattttca attctatcaa agtagaacat ggcgaaaggc ttcatacttg tatcggttaa
    27841 atcatccagt atgtgaggat tgcctagaag aaggcttgat aaggaaagct gatgttgtag
    27901 atcacaaaat tgaactaaaa gatgattgga atagacggtt agatgaaact aattttcgtt
    27961 ctttatgcca tgcacaccat aattccaaga cagccaatga aagacaaaga cgagaaaaga
    28021 gtaccctttg agttaagggg gcatagtgtg aaacttactg acaatcgatg cctactcatt
    28081 ttggtacaaa taaccgttgt gaaaaggcat aagggtaatt acaaataacg attacacttg
    28141 taatcacaag tgaaaaagta tataatgaaa gtaggagatt tattgaaaaa tacaattgtt
    28201 attactgata aaacagggaa acagcgcacc attgagttac ctcattttgg tcaagtgacc
    28261 attcaaatgc agaacggaaa aatcatttat atagataaat tagataaaga aaaattctga
    28321 tcgaaaaacg aaggaatgtg agcttaattg cttacgttcc tttttctttt gtctgaaagg
    28381 aggacaacat gggacaccct aaaatattac acgatacaaa aggcaatata tcaagtgaag
    28441 aaaaagcaat ccgtgtggac gctagagaag aattgttcaa gcagcaacca ttaataaata
    28501 tcacgccccc tgactggatg gcagcgagcg ctagaagtga atggaatcgt atcgtaccaa
    28561 cattaaaaaa agattatcca ttgagtgaag cagattatgg ttcattggta gcctattgtt
    28621 tagcctttgc tcgaatgaaa acagccgaag ccgagataag aaaatcaggt acgtttatca
    28681 catgcgaaaa cggagtaaag aaagccaatc cagcggttcg ggttcaatca caagctatga
    28741 gtgatttgaa aaaacaagcc acctcactag gtatgacctt agaatcacga tcaaaactag
    28801 ctttgaacaa ggttaaaaat gatgaacccg aagacccgtt caaagagttg atgaattcat
    28861 gaatgattac attgagaaag tcctatcagg taagctgatt gcacccaaga aaattatcca
    28921 agcgtgtgag cgtcatataa gcgatttgga gcgttctaag tcagatagct tcccttatgt
    28981 gttcgatgaa gaacaagcca ccaaagcgat taaattcatt gagttgctac catctacgga
    29041 cggtaaagca atcaagatgt taggatttca aaaattcatt ctaggcagtc tttatggctg
    29101 gcgtactaaa gaagggaatt acaggcgatt caatcgagcg tttaccagta tgagccgtaa
    29161 gaatgggaaa acgtatatcg caagtggcat ggctgccaat gcgttgatta tggaacaaga
    29221 accagcagaa gcaaggcaag tattgtttgt aagtaacgct ttgaaacaag ctaaattggg
    29281 ctatgatatg ctgtctaatt cacttagaaa cgtggtcaag tctagtaagt ttttaagacc
    29341 acaactgaaa attatgaact ctaagattca gcacttgccc tctaattcgt tcgctatggc
    29401 actggctagt gaaaccagca cgctagatgg gtttgcacca acaaccgcaa ttcttgacga
    29461 gtggcacgaa gcaaaaactc gtaaaacgta caacgtcatt aagtcaggaa tgacccaaca
    29521 aaagaacggc ttattgtgtg ttattagtac cgctgggctt gatttaaacg ttcctatgta
    29581 cgaggaatac ttattgttag atcgtgtgct aaaaggcgaa gaacaagccg acaggtactt
    29641 tatagcgata tgggaattgg acgatcccga agaaattcac gatcaagaga aatggatcaa
    29701 agccaatccg atttttgaaa gtgaagaaat caaaaaagta atgattccaa ccattcaaga
    29761 tgatgtgaac cttgctttga aacaaaataa ccttaattct gtattggtga aaaacttcaa
    29821 tttatggaga caagcgagtg aggacagcta tatgattgct gaagactggc aggcaaccga
    29881 agtagaacca caagatatta caggcaagcc cgtttatatc ggagtggatt tatctaaaac
    29941 agatgattta actagcgttt catggatcgt accgctagat aacggcgaac tttattgtga
    30001 ttcacatagc tttgtagcca ccaaatatgg gcttcaagac aaagaaaagc gcgacggttt
    30061 gccttatcga gaactagaaa aagctggtga gtgttccatt actcaattag aaagtggaat
    30121 cgtggactat gaccaagtat ttcagtttat tcaagatttg attcaagaaa atgatttgga
    30181 atgtatgggg atttgttatg acccgtataa cgctaattcg cttatcagta aagctgaaaa
    30241 agccaactac ccaatgttag aagtaagaca aggaacgatt actctaaacg ttccgacccg
    30301 aacttttaga gaacaagttt atgaaggcaa cgttattcac aataaaaata cgattctcac
    30361 ccatgcagtg aacaacgcta ttttaaaaac ggataacaac ggcattcaga ttaataaatc
    30421 aaagaacagt aacaaaattg atccaatagc tgcattaatc aatgcctatg tgtttgcaat
    30481 ggattacttc accacaacgg aaggagcgaa agcagacaat gaattttata caagtgaaga
    30541 attttctttc taattacatt cataccgttc ttttacttct tggattggtg tgtgtgttgg
    30601 ttgctatcac cttactaaca aatgtctact atggcttgtt agcgctgggc atagtgctta
    30661 ttggggtagc ggtcatgcta aatacagaac agaagggagg ttaaaagatg gcatttttta
    30721 aagcgagaca aaatacaacg ggagatcctt tcctacaaca tgtggtatca atccaatcgg
    30781 atgattacac caccagcttt acaagcgttc gtgcattaag aaatagtgat gtgtttgcag
    30841 ccgttcgaat tattgctagt gatattgctt caagtccgat tcaattggtc aaaaacaata
    30901 tgccacaagc tgataatgaa ctggtgaagt tactaaacga gaaacctaat tcagaaatgg
    30961 atggttggca tttaaagttt gctttggcgg tcaatatgtt gctaaacggt aatagctttg
    31021 cagagattaa acgcaacggt gaaaaggtag aagaaattca cttattacct aactcaagtg
    31081 taacggttac tcaattagat aatggtacgt tgtcttatca gattggtgat aaaaaaagac
    31141 gtgtgaagtc tagcgatatt ttgcacttca aatatttcac ccaagatggt ttaacaggat
    31201 taccaccact ttatgcgtta cgtgatgaac tgaaaattca acaagctggc aaccgcacat
    31261 tgcacaattt ctttactcgt ggtgtcagtg ggtcaggtat tttgaaggtt cataagtcag
    31321 atttagacgg atcagcaaag aacgcaattc gtgaaaagtt tgaagaagcc aacggttcaa
    31381 gtagtggaga taatgctctt agaacgatca ttcttgatga aacaatggac tacaaaacat
    31441 tagaaataaa caccgatgtt ttgaagctta tcaattccaa tgattggaac acaaaacaaa
    31501 ttgccaaggc gtttggtgta ccgattgagc gtttaggcgt tgaaaatgaa cattctagca
    31561 ccgttcaaag taatctccag tatatccaaa gtacgctgat tcattacttt aatgtgtttg
    31621 tgagtgaatt agatacgaaa cttgaaacca atatccgctt taattccgat cagttactag
    31681 agactgatcc tgaaacaaaa gtaaaaaatg tattggatca ggtcaaaggg tcacttctca
    31741 cgattaatga ggggcggtcg aaaatggggc taccccccat ggatggtggc gatcgtttac
    31801 tagcaagttt gaactttacg tatttagata cgttggagaa atatcaatta aaagaacagg
    31861 aaggagttac accagttgaa taatgaagaa gaaaaggaaa aacggctgac agaagaagct
    31921 gagctaacag ccgattctcc caaagtagag aaagaaaatg aaaaacaacc aacagacggc
    31981 aaaactattt caggctatgc gttgaaattc gggcaaccgt caaaagattt aggcggcttt
    32041 gtagaagtga ttacacccga agcattaaaa gaggtggatt tatcaaatgt gttcttatta
    32101 tatggacacg attattcaaa gccactagct agtgtcaaag caggtacgtt gaaattgaat
    32161 gtcgatgata caggattaca ttttgaagca gagctaaccg acacgaccta ttcaaatgat
    32221 gtgtatgaga atatctcaaa aggggttgtt gattctatgt cctttgggtt cgtgcttgga
    32281 ttagattcat tcgacaaaaa agaagatggc acaattgaac gatcaataga taaaatcaaa
    32341 gcacttaatg aaattagtgt cgtgaccgtt cccgcttatg attcatcaaa tgtccaagta
    32401 aataagcgtt cttacgaatc gtttatgagt aacaaccaag caaaacaaac aaacaatagc
    32461 ttagaatcca cttctaaagc acaaaaggag agtaataaca tggaaaaaac tttaatcgat
    32521 aacgaaaaaa cagaattgcg tgggtatgaa gaatatatcc gttcacaagg cgaagtgcgt
    32581 gatggagtca ctactgtaaa tgcagcggca gttgttcccg aagaagtaat cggtgaagtc
    32641 tttgatttga aacgttcaaa ttataactta gctcaatatg caacagtaaa aacagtatca
    32701 aatggacaag gtaaatatcc agtagcaact aaccaacaag cagtgttagc aacaaaagct
    32761 gaacttgctg aaattggtga tattgacgct gaaatgttta cttcagttga ttataaagta
    32821 gaaactcgtg ctggtaagat tgccttatca aatgaggttg tggaagattc agcagtgaat
    32881 attgtacaag aggtcaaaga tcagttagcg aaattggtag aaaacactga caataagcat
    32941 atcatggatt tattaaaaac attcactaag aaaacggctg ctacgttgga cgatttgaaa
    33001 caactataca atgtggcatt agacccagca ttaaataaaa tggtaattct aaaccaaagc
    33061 ggatattacc acctagatac attgaaagat tcagatggac gttacatttt acaacccgat
    33121 gtgacagcac ctagtggtaa atcattattc ggtatgccag tagtattgat tgcagataca
    33181 ttgtttgcca atcctaaagc tggaacattc cctatgatta tgggggatat tgcacaatct
    33241 atctttgttg ctcgtagaaa tcaagtaacg actcaatggg aaaaattcga ttactactca
    33301 caaggacttg cagtgatcgt tcgcaacgat tataagaaaa ttgatcaaaa tgcttcagtg
    33361 tatattgagt ttacgccagt tgtaacacca aaagtataga aaaatattgg gcggcggttt
    33421 atcccactgc ctttttttca ttaggagaga taaaatggta attttggata gcataaaaaa
    33481 aagtatgcgg atcgatcaca ctattgatga tgactttatt caacaattga ttgatacagc
    33541 aggcgaatat ataaaaagtg ctattgatag tagcgcaacg gataaagata tggataatta
    33601 tcagcaattt gatttggcgg tgtcattact tactcaacat tggtatttga accgtcaaga
    33661 agccagcagc gaacggatac cagtaacggt acaagcatta gtacaacaaa tgagaggtgc
    33721 ttattatgcc aatcattaag aatgtaaatg aattgactga gagagtcaag tttaaaaaga
    33781 caaaacgggt aaaagatgaa gatgggcaga tggtggatag tgaagaaact gtatttgaat
    33841 gttgggctaa tgtgcgttca caaatgctaa aagacgtgct tgctagtgta ggtaccattc
    33901 ttgaaggaac gttgacgttt attattcgat acgatcaaga ttatgaacta acaaacgata
    33961 tgaaagtagc ttggaaaaac aagagttata aaattatttc aatcaatgaa ggaacggcgt
    34021 ttaaagatta tacaacgatc atagctaaac agatttctta gaatgattac acttgtaaac
    34081 gttgtgggta tttagtataa ttaaggtagt aaatgaaggg ttagctgcct gaattttgca
    34141 agacttagct agtcgaaatc tattgttgga ctgaaaattg taggtgtggt tgcaaacatg
    34201 ctggactaag aaagatgata gatgatgaac gttcaatttt aatacaggca tgctaggact
    34261 gattggatgg ttttggcaag ctgattgtgt agaaatcaaa gaacacgtct gttgtggacg
    34321 tgtttttttt gttataattc aaaagaggtg atttaatgga caaagcagag tttacaaatt
    34381 tttattggaa gtattatcta catttagaaa atgagtttat taataccaca gattttgtga
    34441 tgctcgatga gaataatttc aaaacattct ctattgaata tcaaaaacta ctactagcga
    34501 ttggttcgga gtgtgagatt attttcaaag aactttgcgg atttgatagc agtagcaata
    34561 aaagcataac tgattttaaa gctgttatta aatctagcga attaatgtgt ttggataatg
    34621 gtgttagggt tatgaattct ttaacattga cttcactaaa accttttgga gatgggtggc
    34681 ctgaagatac accagattgg tggaaaatat ataacagagt aaaacatggt cgttcttcaa
    34741 attataagga agcaaatttg gaaaatgtgt tgtatgcttt agcaagtcta tatttattag
    34801 aggaatattt gcataagaaa gtaatactag aaggtgaagt agactttata agtccagagt
    34861 caaatctatt tacgttatct tgggaaagaa aacattcgtc gatgcaaaaa gtgacgtttg
    34921 aaaaagtgga ttcaaattat gtagctccac tcattgattt taaagaacaa gaagaaattt
    34981 aaaaaccccc acggcttatt gaagtttttg tatgccatat tgtatgccat ttggtttaaa
    35041 tcgcttgaaa aatagtgata gataactcta attcatttag tcataaacgc tgttttgata
    35101 acctttatag ttctttgata tgggtttctc attcatggcg gaagaagaag aatagaacaa
    35161 aagaatgaat taataagata taaaaaaagg gattgtgaca aacgtcttgt cacaatccct
    35221 ttttccaaat aaacgatgtt caatcagctg cccctcggca ttcgctcgaa aaacggcgaa
    35281 atatgaagaa ctattttgcc atttgtttct ctaataatca ggtcaaaacg ttgacttcac
    35341 agtctcttcc ttaaacggtg ttctcctgcc aactcctcgg tcacaagtca caatattcaa
    35401 caaacatgag aagctgtttt ttgaaattgt tccttgtgac tcggagctga acggcaggct
    35461 cacgacctct ttcttaaacg gtgttcaaaa gcttgcatct gcggtaataa gttcaaccaa
    35521 acgaaaatta tgaggagcta tttttgtttg gctgttctta ttacttgatg caggacagct
    35581 ttttcacaac ctcttttcgt ttagcactaa atttccttaa aaagtagaaa agctttcgaa
    35641 gcctcgtttg tttcttttac tgtataataa aagaaaagag taacaatcgc taaaagatat
    35701 aaacaagaga aaggaaatac aagatgattg gtctgattta ttttgtggtg atcgttctgg
    35761 cgaacacagt tggcgctatt tccgggatgg gtggaggcgt gttgatcaaa ccgattcttg
    35821 atcttatcgg cgcccattct gttgcaggga tttcttttta ctcaacagtt gcggtattca
    35881 cgatgtccat tgtttcgact gtgcgacaag tatcaagcgg gaaatcactg aattggcaga
    35941 ttgtcggttg ggtatctagt ggagctgttg ttggaggagt agtcggcaac attgtattcg
    36001 aagttttttt acagttattt gaaaacgaga agcatgtgca gctgatccaa atttttttga
    36061 cggtattgac cttggttttt gcgttcttct acaccaagca tcatcagcca aaatttcatt
    36121 tgacgtcatg gacttggtac cttatatgtg ggggggttct gggcttttta gctagttttt
    36181 taggtattgg tggtggacca gtcaatgttt ctttgttgat gctgatgttt gcattgccaa
    36241 taaaagaagc aacactatat tctctatcta cgattttctt ttctcaactg gcaaaattgg
    36301 taacgattgc tttaacaagt agctttatgc gctttgattt atctatgttg ttttatgtta
    36361 tccccgctgc tgttattgga ggtttgtggg gagcaagatt tagcagggtt ttgtctccaa
    36421 aaaaagtgac ctttattttt caagtaattg tcctcgtggt tcttttggtc aattgttaca
    36481 atgcctttgt catcttacaa acattaggag aatctagact aacgcaagtc aaaatcactg
    36541 aaacatattg ttctaaatga aaaaaagagt atactatgat aaaaaaattc attttaaaaa
    36601 atcagaaatt ggctggtgat ttggatgtta cgggaaatgc gtttagaaga tgcagaagca
    36661 ctacgtgaaa tcaatgcgga tcaattaggg tatgatatac cattaaccgt tacggtgaga
    36721 caaatgaaga aactgctgaa ggagccagag aaaaattttt tcttggttta tgaagatcct
    36781 acttctaaaa aagcagctgg ctatgtacaa gcggagtcct atgaatcgat ttttagcgat
    36841 ccaatgttca atattatggc acttgctgtg tctaaatatg ctgaaaaaag aggcatcgga
    36901 aaggctttga tgactggcgt agaagaagaa gcgaaaaaac gaggaataac gacaataagg
    36961 cttaattctg cagaatacag agtagaagca caccaatttt atgaacacat cggttatcat
    37021 tccgataaaa tgcaaaaaag atttttgaaa atcctgtaaa tctttatcaa aaaaataccc
    37081 gatcaccaag ccgatacttg atgatcaggt atttttgttt ttttgactaa gaaagtaatt
    37141 gcatcaagaa accagagatg atcaaaacga tggcaccacc aagtcgattg cccatttgag
    37201 caaaagcaat aagttccatc cgattagctg cagataagac ggctacattt cctgttccgc
    37261 ccatcgagtt gttgcataag ccagcagtaa tagttgattc aattggatat aaaccaaaca
    37321 aacgaccgac aaatcctgaa acaactgaaa tcgcgataac acttgtcaga cataagacaa
    37381 caaattgcca tgtcaaagca gaagctaata cattcagatt cagcaacgca ataccgatac
    37441 cggcaagaac agctgctgtc aagtttttga caatcaagtt attgaacatg atagctgcat
    37501 cttcataata ctctggtaat aggttggcga ttttacagat gacaacgata ataatcataa
    37561 atgcgtaagc atggacttta ggaacaaaat agttaccaat ttgtcctaag atgaagaaag
    37621 tcaatgatac catcaaacca acacctaact gtggaatgga aggtttcaca gttcgaggtt
    37681 ttccatcgcc aagatcgcct ttttccatta atttaccatt gccgttgaat tttggcattg
    37741 attgtccagc acgagcaact aatgctgcac cgatgatagc taagacattt gtcattgctg
    37801 tcgcaggaat caggcgggaa atgatagaag aagcatccgt acctaaaaca tttgcataaa
    37861 tcgttgataa aggaacggct ccggctccaa caccaccagc catcgcaggt aatgagatgt
    37921 ataaaacgga atttgcaaaa ccatttccga taagcatgcc cacgagtcct acggcaaaaa
    37981 aggagacgac cattgaaata agtgcaacgg gaataaaacg aacagaagct ttcatcaata
    38041 gattacggtt cataccaagg atgctaccag taatcaaggc agcaatataa aagtcccaaa
    38101 agcccatatt gctgacaaag ttttctgtgg atttcactac atattcaggt aagatcccaa
    38161 atgtagcaat cgcagcagaa gcgaagatcg caaaaacgga accaccaccc aaataacttt
    38221 tgacgatagg gatttttgtc ccgataaaat gaaataaatt accgaaaata accaaaactg
    38281 cgattggtcc aatcatattc gtcggtaatt tccctaaagc cattgcaatg atcaggacaa
    38341 ggaccatgat caaataaagt ggcaaactta cgccggtgat ttttgtggac caaaaacctt
    38401 cttttttctt ttcctcaact gcagttgcag ttgttgtttt ttgtgccatt tttacagatc
    38461 ctttcttatt ctgtatcata tgaaaaaagc caaagaaaag cgacaaaaga gcaggagttg
    38521 gctggccgct gttttgccgc agtcgctttt ttctttttag acgtcataca aagtttctgt
    38581 atgttctttt actataacga tcttaatctt ctaaagattt atattcagga acccatttag
    38641 cagattcaac tgcttctttg atatccgtga tttcttcacg attcaagttt tgtgcgacaa
    38701 ctgattttgc gacagtttca gcaatcgttt gagaaaattc agtgattttt gctactggag
    38761 gcaagatagc tgctcctggt tttgttacat caacgattcc gcctaatgct cgactagctt
    38821 gagaaatgat ttcagcattt actcgtgtag ctgttgaagc aatcaaacca agtcctaaac
    38881 ctgggtacat caaagcatta tttgcttgac cgatttggta agttacacca ttatattcaa
    38941 catcagcagc agggatacct gttccaacta atgcttttcc gtccgtccat tctattaaat
    39001 cttttgcttt tgcttctgcc aattttgttg gattagacaa aggcatgatg atcggacgtg
    39061 gtgtatgagc agccatttct ttcacgattt cttcagtgaa tgctccaggt tgggtagaag
    39121 taccaatcat gattgtcgga tggatcgctt ttacaactgc ttctaagttt gtcaattcat
    39181 cagcattagt gaaatctgag cgtttgcgag cgaatgggat ttgaccagga gtcaatcctt
    39241 ctgtatcttc aaacaataaa ccttgtttat ctacttgata gaaatgttgg cgtgcttctt
    39301 cttcaggtac accttgacgg atcatctcat ctaaaaggat gtttgcgata cccacaccag
    39361 cagtaccagc accaaatgtc aaaattattt gatctttcaa ttgttcaccg gatatattca
    39421 atccgcctaa tacacctgct aggacaacaa ttcctgtacc ttggatatcg tcgttgaaag
    39481 tagtgatttg atcttcgtat ttttctaaga tcgctgcagc atttcctcgt ccaaaatctt
    39541 cccaatgcaa taacaattct gggaataatt cggtagctga ttgaacgaat tgatcgatga
    39601 attcatagta agtttcgcct tctacacgag catgacgatt gcctaagtat aagggattat
    39661 tcaataattc ttcattatta gtaccagcgt cgatcgatac aggcaaaact tgtgctggat
    39721 taataccagc agcagcagta tagaccatca atttgccgat agcgatgtca acaccgttca
    39781 caccccagtc gcccatacct aagattcctt ctgcatcagt cacaacaatc aaacgaatgt
    39841 ctcgtccatc tgccgcgttc ttcaaacttg ctttgatgtt ttctggttcg tcgattgaaa
    39901 gaaatgcagc atcttgcggt ttcaagaaaa tttcgttgta ttgttcgatt gaatccgcaa
    39961 cgacaggatc ataaacgaca ggcatgaatt caactaaatg ttcgcccatc aatttataaa
    40021 acaatgtccg attcgtattg aatagattca ttaagaagat acgtttttcc aaatctgttt
    40081 gtttgcttaa gtattgacca taagcttgaa cagattgttg ttccagtgtt tggacagtac
    40141 ttggaagcat accagtgatt ccatattttg cccgttcttc ttttgtaaaa gctgttcctt
    40201 tatttagaaa aggattattt aataagttta accctgtaag catgaatgat tcctcctaag
    40261 ttttaataca aacgaagtat agaagtcaga tgatgatata gtcaaaaaga gcaggtatga
    40321 taaattttat ttatatgtaa tatagccaaa agaaatcaaa atagcagtat ttgttctttt
    40381 tatatcgaca atccttgctt gaatactatg cgtatctctt atatgctaga gaaagaaaag
    40441 tagaagaata agggatagat ggaatggata aataggattt ctgaggaaaa aagcacatga
    40501 tagcgttgat aggagtcacc tatgtcaggt gataaaaata cataagtaga aaattaagag
    40561 gaggaagaga aaatgaaaga agttcaattg attagaaaaa gcgaactatc agaaggcggt
    40621 tgcaatgcat gtggcgtagt agaagcgaca agctatacat taaaattaga ttccaatcaa
    40681 gcaataatct ctgaactgac agtaggcggt cttgtggaca gtctggcgct tgctgaaggt
    40741 tttactggag aagatattta tgagatgttt tcagaagtcc gtcagttaaa aaaaggagaa
    40801 aaatgcatag aggttcatca tgagagcccg aatgtgaggt tcaaacgtgg tgataatgag
    40861 atgatcttca agaatcatgt gtctgatcac actgaactat atgaaatcgt gaatcaaata
    40921 ctgtctggga tttttgaatt aggaccttat gagttcaagg aagaaaacgg taatccaaaa
    40981 ttaaatgaag aatggcaaga aacgattgaa acacaaagaa acaatccaca cttatttcaa
    41041 tagtcttcca cagtatttcg taaaaatgtt gatgaaaaag aaacaccgtg aatcagaggt
    41101 cgtgaaaaac ctgccctgca tcaagtaata agaacagcca aacaaaaata gctcctccta
    41161 tttttcgttt ggttgggctt attaccgcag atgcaagttt ttgaacaccg tttaaggaag
    41221 agactgtgaa gtcaacgttc tgacctgagt attagagaga caaatggcaa aatagttcct
    41281 catattttgc cattttttga gctaataccg agggtcagct gattgaacac cgttttatcg
    41341 agaggttgtg aaaaagtcgc ttagtttcga gtagtaagaa aaattttgtg aaaatggctt
    41401 tccacatttt tgcataaatt tgacttaata ccgagaaaat ggcttttgaa caccgtttat
    41461 tcaaaaaaag ggactttgac actacttttg tcaaagtccc atcggttttt tatctatttt
    41521 tattacaatc atttcttcca gagtagtgac atctggaatg gctgaaatgt aaacagatta
    41581 tttgcctgta tcaatgtcga agagtaatat aaaaagtgta aacgctatca tattgttcat
    41641 cattcaaatt ttatagagag aaggcattga gatggaaaaa acatatcaag caggtacaaa
    41701 tgaaggaata gtagatttta tcaatatgga agatttagaa atcgcggctt cacaagtgat
    41761 tccagctggt ggttatggtt acatcagcag tggtgctggc gacttattta cttatcaaga
    41821 aaatgaacgg gcattcaatc atcgtttgat tattcctcat gtattaagag atgtagaatt
    41881 acccgataca actacacatt ttgacgaaga aatgctgact gcaccaatca tcatggcacc
    41941 agttgctgct catggattag ctcatgtgaa ggcggagaaa gcttctgcaa aaggtgtagc
    42001 agattttggg acgatctata cagcaagttc ttacgcttct tgtactttag aagagataag
    42061 agaagcaggc ggggagaaag caccgcaatg gtttcaattt tatatgagca aagataatgg
    42121 aatcaatttg gatattcttg aagtggccaa gcgtaatgga gcaaaagcaa tcgtattgac
    42181 agcggatgca acagttggcg gaaaccgtga aacagaccgc agaaacgggt ttaccttccc
    42241 gctgccaatg ccgatcgttc aggcttatca atcaggagta ggccaaacga tggatgctgt
    42301 atataaatct tccaaacaaa aacttagtcc aaaagatgta gaatttatcg ctgctcattc
    42361 tgatttgcca gtctacgtga aaggtgttca atcagaagaa gatgtctatc gatcattaga
    42421 atctggtgct ggtggaattt gggtatctaa ccatggtggc cgtcaattag atggggggcc
    42481 tgctgcgttt gattcgttgc aatatgtggc agaagcagta gataaacgtg taccaatcgt
    42541 gtttgacagc ggtgtacgac gtggacaaca tgttttcaaa gcaatcgcat caggtgccga
    42601 tcttgttgct attggcagac ccgttattta tggattgtct ttaggaggaa gtacaggagt
    42661 ccatcaagtg tttgatttct ttaaaacaga attggaaatg gtcatgcaat tagctggaac
    42721 acaaacagta gaagatatca aaaaaataaa attgcgtgag aatcgtttta tttaagaaat
    42781 aaatgacgaa aaaaatagga gtgcggcaga tgatgccgta ctcctatttt tatagttcaa
    42841 ggatgtcact aatagaataa tttgaaacga aaaaataaaa ttgaaatatt gtttcatact
    42901 taataaaaaa ggaagaatat tcatgtaaac gattttattg tttttttctc ttttatacaa
    42961 aaagggtcat aatttcaagt aagcggatga attcatgagg attttttgca tactgtctct
    43021 actatactta ggtcactaag aaaaaggagt gatttattat gaaaaagaac atgattggga
    43081 cattattact ttcaacactt cttctaggcg gcttggcaac accagctttt gctgagggtc
    43141 aagcgacttc aaaaggagat attaccttta ctgaaccaac aaataccgtt gagcctctta
    43201 accctactga tccttcaaaa ccagtagagc cagcagatcc ggaaaatcca gcaactggcc
    43261 agacaggttc tttaacattg gatgtagttc ctgaattgcc atttggtaca cacgagattg
    43321 aaagcggaac aaaaacgtat caagtagacg cttcaaaaaa cgatacacct tatctccaag
    43381 tatcagatcg tcgaggtgta ggtgcagatg gccaagcaca agggtggaac gtgacagttt
    43441 cggtttcaga ttttgtaaac ggttcacaag ttttgcaagg cgctgaatta gattttggaa
    43501 catccactgt taaaagtacg tcagataacg aatccactgg accaactagt caaactgtaa
    43561 ctgggttgag taaagcaagt gcagcgacac caatatttac agcagcaaaa gatcaaggtc
    43621 tgggaacatg gctttctgtt tatgatccag caaatatcac actgaaagtg ccgaaagcag
    43681 cagctggaac attcacggct gatttgactt ggaacctcgt ggctggccca gtagcataga
    43741 gtatgaaata aattcaacaa actgcggtga aaatactata ggtgaaggat tttttaccgc
    43801 agttgttgtt gaaaggatgt ggtggacaat gaatcaaagt aaacgactgt ttgtttcgtt
    43861 tttttctatt ttaagtctat ttttcatttt tccgtcaatc agccaagcaa aggattcagc
    43921 aggagacttt ggaatcaaac cggtatttcc agagaaccaa atagataaag caatcggtta
    43981 ttttgattta ttagtggcac cggaacaaaa tcagacacta gaagtaatta tcagcaattc
    44041 ttcagatgaa gaacgaacat ttgaggtctc tgtcaatccg gcggtaacga gtgatggtgg
    44101 aacgatcgat tatagtcaaa aaaacccaac gttagatgag acattgccgt ttgatgtccg
    44161 tgacgttttg ctcattgcga aaaaggaaat caatgtatca gcacatgcag aaacaactat
    44221 acctatagaa gtgaaaatcc cagcaaaaag ctttaaggga cgtgtattag cgggtattca
    44281 tgtttcacct aaagaagaag ctgaaacaga aaatgctaca gaaggagcac aaatcaaaaa
    44341 tcgtattgct tataatctcg cagtcgtttt acaagaaagt caagagacga tagaaccgga
    44401 tctgaaactt ttatcaggag atttggacga ggtcaacgca aagccaactg ttcagcttcg
    44461 tttccaaaat cctcagccta ggattatcag caatttgata tttacgagca agatctttta
    44521 tgaaaatcag ctttatattg aaaatacgtc taatgaattt ttagttgcac caaattcgaa
    44581 ttttcacttg aatcttgatt tagctggtga taaagcaaaa gccggcgatt accgcgcaga
    44641 aatcatagca aaatcaggcg acagtaatga atggcgattt acacaaaact ttacgatcaa
    44701 aaaagaaaaa gcacaaaaag taaatgaaaa ttccgttttt gcagtacaag aacaatcttt
    44761 cccatggctt tatgcaggat tggttgctgc agttctagtg ttatggttga ttttgctgtt
    44821 tttgtgggtc cacaagaaaa agaaaaaagg agaaacaaca tgatgaggtg atttcgttga
    44881 aaacatcgat cttattggga gggattattg caagtttgct gttcttcagc tggcaagagc
    44941 cagtccaagc agataccaaa agttcaggta cgattacatt ttatgatcta agtccagttc
    45001 cgcatccaag tggttcagtc aatggcgcat caaaacagca gacacagcta ccgatttata
    45061 aagaatctaa tcaacatggc gtattcccgg agacgaatga agaaaagatc cgttttcttt
    45121 atttgatcat tggtatagaa ttatggcttc ttgcgtggtt gttgttatgg agaagaaagg
    45181 aaaaggagga tgaacatgtt gctacaaaat aaattttcat tttttcgctc cttctttttt
    45241 acttcgcttt ttgttttaag tatatttatc ttttcacctt cggcagaagc tgttggagca
    45301 acgcctcctg ccatttctta tgatccatac acgtatgaaa atatcgtacc tccaaatggt
    45361 ggacgtagtg cagtcaatgg cgggaagctt gtccaactaa ctggggctaa ccaattgcct
    45421 aaattgactg ctacttattt gaacgatggt tcaaatgatc cttggaaagg tggcacggtc
    45481 cgttttcatt gggaaagcca tgtgaaacta acaaatgtac ttgatttggt gaatatcact
    45541 gcacaaggat ttgcatttgt ggcgatcatc aatttgccgg aacatgtatc aagcagtgat
    45601 gtattaaaag caattgactg gaacaacgcc tacttgtata ttgccggtgc ccccatcaag
    45661 gttactagcg gtagtttatt atcagcagga agccatacct tgcgttttgg gatggggtcg
    45721 tgggatacaa atactctatt ggcagatatt attgctatta ttacgcgagg cgaattcaac
    45781 gtggacgata tcccgcttca atttgatgtt acagctaatg tcgcgaagat gacagaaaac
    45841 ggagataaat atgatacgag tccaaacaaa attttgacca agggtaaatt acaaccttct
    45901 atgtctaaaa aggccgtttt ttctgttgat ttttatgatt cgaataatat tatccaagat
    45961 cgtatgttca attcgatttt agctccagct gcaggtagat tttatcctaa attaactggc
    46021 ggaaacttga atccaggagc atatgcattt tctgcaagtg cagagataaa tacgtggaat
    46081 agttacatct caacaagtga ttcaacagga aaatataata catttgctga taccacagaa
    46141 tacgtggatg gaaataacca gaaccttcca ggctctacca atagtcggac attgacgatg
    46201 gggctgactg aaggacgttt tgatcagttg ccatttagtc gctttgatcg cgtagtcaac
    46261 tattttacag gaaaaaacgt tacacaagga gcaatactga ctcatactcc agcaagcaca
    46321 agtggattga atcagacagc caatatcgtg tacagtggga aagatgcgca aggcggattg
    46381 ctttctcctg ttgctttaaa ggtattggag cagtacaagc tagacggaac ggttttacca
    46441 acaaacttaa cagccgatag tcagtgggga aagctccttt cttctgcatc gtaccaagtc
    46501 acggccaatt ggtcagcaac tgaactaaaa aagggttcga tccattacag gctttattcg
    46561 aaaggaaccc aaaaattagc gacaggatgg acagatcaac ttttccaaac gatccaatca
    46621 aataacgggg gtgtaaatac agctacttct acactacctg cattggcttc agggcaatat
    46681 tattttgatt atcgcttggt ggacgatgta cttactaaca tgtatccgtc ttttgcgtac
    46741 aaatggcagt ctgaacaagc tggaatcacc actcttcctc aaataacagt ggctaatttt
    46801 ccatctgtga gtgcagatag tcagctaaaa aaccttagca gacaacctga gacaggagat
    46861 cccctgtctg ctctatcagg agatacgatt caagaaaatg tgacattcac gttaacaaaa
    46921 tctggggatg cgataaccga caaaaaaatc acgatctcac ttcctgaaaa tactacttat
    46981 atcaatggtt ccttaaaatt aaatggtaca actatcgcag ataccggcat tcaacaagga
    47041 gtttctgtcc cagcagatct attgagcaaa ataggagata ccattcatct tacttacaac
    47101 tatcaattaa atactgtaga tacttctgta caatccgtca gcatactgac aaaggcagct
    47161 gtactttcca gcaatattac attagcagat ggtgctaagc ttcctaaccc agttgtccaa
    47221 acatctgcta aaacaattct tgtccccaaa caagaattaa cattagttaa tgtaccagat
    47281 gattttacat ttggtaacga tctccccaaa ccgttgaaga caagttatta tgaagcaaaa
    47341 ggcgattttt cttttgatgt gcgggatact cggcttccaa gcacgtctcc ttggcaactg
    47401 acagggacat tgacttcttt atttaagaat gatcaaggtc aagaattaag cggaacaaaa
    47461 ttatacttca atcattctgg atcaaaacaa ttgattcagc aaggtcaaaa cacgttgatt
    47521 tatgagagtg atggaacagc taaaggagag gttctcgttg actttcccga taccgatggt
    47581 ttactcttag aggtaaatag cagtacgaat gctcaacctg gcgcaacgta tcaaggcatg
    47641 gtcacatggg aactgacagc tgggccaacc agctaagtga ttagaatttg tatggatctg
    47701 tgataactgt cacagatcct ctttttcaag gatgagaagg aaacttctgc tgttaaaatc
    47761 agaaatgctt ggaggagtgg acttggaact tttcagtttg cttgaaaaaa atgaacaacg
    47821 gcaaatcaaa cttttccaac ttttattaga ggaaaaagga gagatttccg ttaataacgt
    47881 acttacccgc ttatcagttg atcgggctac cttgaaagaa gatctgtttt atttacaagc
    47941 taacttggaa aatatcaaac aattggaaat tgttatccaa gaagggaata ttttattaat
    48001 cagacatgga aatatagcag cagtcgatgt ttattatcat tgctacttgc gctattctac
    48061 aaaatatcag atacttcttt atctgttgga aaatggctca tttgatcggc agaaacttgt
    48121 catggaactt aatatcagtt cggctacttt gtctcgcaga gtgaaggaat taaatgattc
    48181 tttaaatgag tttcatctga aaataaaaag cgggcggctg accggtccag aaagtcaaat
    48241 ttgttatttt tatttccaat tattttggtt tggacgtcct tatcttgaaa acaaaaaaga
    48301 atacagtgat ttatcaggaa acactttttt agatctgctg caaaaagagt ttagttttac
    48361 tattacagaa gaaggacgat tgaaatttga aatatggctt tccattatga agaagcgaat
    48421 gcgctgtacg aaaaaatcca aaccagatta tagcaatctt cctgttggat tgtttcaaac
    48481 gacacaattt ttattggacc tccatacatt tttgacccgt tacttctttc aatatgcctt
    48541 tccttggaat caaaatgaaa cgttggtttt ttatcttttc atgatcagta actttacatt
    48601 agatacacat aactcgcatg tccaggagtt tttgataagc gaaaaataca aagacgacgt
    48661 agtagctcaa ttgaatcgaa cgtttaaaca atcgatagaa gaatatttct ctttttatgt
    48721 ttttccagaa gagatttcgc aaaagattgc gttgacagtg atgcaaaatc acgctcattt
    48781 tgcctatttt agaggatgga tgaatatttt tggccaagaa ggattaaaac agcggttaac
    48841 tgaagtagaa gataaacaat tcctggtttt atgtgaaaga ttggtcagac aaacatttgc
    48901 tattgttgat tttactgaag tagacgagga aaatgcccgc tttgaattat ttgctcgcta
    48961 tgcatctatt ttgcggacgc tgatcaagca gttagaatta cgtctgcaaa ttgcttatga
    49021 tcttccttat gaaaggctaa tggcggatat cgtgaaagaa atcatccagg aacaattgct
    49081 gaatacgatc aaatatgatt tagtcgaata cgagaaagaa aagcagtatg atatcatttt
    49141 gactagccaa ttgaaagagt acccgtcaca gaagtccgct aaagtttttg tattcactag
    49201 caacgaatat aattatgatt tcccctattt gaaccaattt ttaaaagaat gttatttaga
    49261 aaaattgaat ttaaggatga ataaaacatg aaaatcgtga tcattggtgc ttcccatgca
    49321 ggcatcacag ctgccctaaa tctaagaaaa cttcaaccga aagcagaagt tttactgatc
    49381 gatgaagatc ataaagatgg actaggctat gtttcaaatg gaatcaacct ttatttaaaa
    49441 ggaaagatac gtagtttagc tgaagttgcc cataacatgc ggactcttca agaaagtggg
    49501 gcaaaactga tcaccgaatg gagagtaact gaacttgatc cagacaaaca tcagctcatc
    49561 ctcgcatcca aagaaggaaa aaacgagacc ataacctatg ataaattaat cgtagcaaca
    49621 ggttcctctc ctgtcacctt gtataaacaa attgaagctg aaaatgtcta cacctataaa
    49681 aatctagtgc aatctaagca agtacttgcc gctttaaaag aagcaaaaga agtagtgatc
    49741 ttcggtgctg gttatattgg attggaatta gcagatgctt tgagaaataa aggatacatt
    49801 attcatctag ttgattatat gccgaatgtt ttatcaagat atttcgataa ggatatgatc
    49861 aacagttttc aaaatcagct gcaaactaag caaatcaatt tttatccaaa tgaattcttg
    49921 atcgattgga aaaaatcaga agagaaagta gtatccgtac aacttctatc tcaagcaata
    49981 aaggcagata tggtcatttt ttctgcccaa actcgtccta atacgacatt gttaaaagaa
    50041 aaagtggctt tgtatgagga tgagactgtg atagtcaatg aatatctgca gacaagtgat
    50101 ccggacatct atgcgattgg agatatcgtc ccagtcagtt ttgacaaaaa taaacggcat
    50161 ctctttttac ctttagttac tcgagctgta catatggcaa gagcagtagc gctaactttg
    50221 agtggtcagc caaccgctta cgacctcaga caaaagataa cagcagcagt cattatagac
    50281 tactttttag gaactgtagg gctgacagaa gatgaagcgc cattcttgga acaaaatacc
    50341 ggttcgtgtt caggagaatt tgatctattt ccacaatacg atgaagaaaa caaaacagta
    50401 aatgcaaagc tgatctacca tccggataca ttagaaataa ttggcggaca gctgataagc
    50461 caagaattct tattatcaga tttgaacctg cttgcggata tcgtgaaaca caaaactacg
    50521 attccacagc tagcagttga ggattttgga tttctgtctg aacacacctc tcgttttcac
    50581 tacctcaatg agttagcttt taaagtacta gctaagagag caaatagcaa tagagtagat
    50641 aaaagactgt gagaaatatc acggtctttt attgtgtggg gatataataa atattaatca
    50701 atcgagaata aaaaattcat ataatgaaat agcggaagaa ttttttgagc ataatattcg
    50761 ccaaaaattt atcaagtgat aaaattgttg tataaaatga ttatttcagg aggaggagtt
    50821 aaatgttttt agcattaaat gaaattatgc attcaaagtt acgttatgcg ttagttgcag
    50881 gggtgatgtt tttgatcgcc tacctggtat tttttttgac tgggttagct tatggcttag
    50941 ctcaagataa tcgaacagca gtcgacaagt gggaggcaga ttcgattgtg ctttcgaaag
    51001 atgcaaattc aaatctaggg atgtccatga ttactaagaa gatagcagaa gaagtcgaag
    51061 gtgggaaagt ggcgtatctt gcccagacac ctggagtcgt gactagtaaa gacagtacag
    51121 aagaaggaaa aatcaatgtt agcttcttcg gtatcgataa aaatcaattc atcatgccca
    51181 atcttgttga aggaaaagct tttgataacg atgatgaggc agtaggcgat attagtttga
    51241 aagaagaata tggtctagcc gtaggagata cagttaagtt atctggtagt gacaagacgt
    51301 ttaaactaac tggctttacg gatcatgcca aattcaatgt ctcaccagtt ctctatacaa
    51361 ccatcaatgc ttaccaagag atccgcttcg aaaaagaaga tacaagtgaa aatgcacgga
    51421 ttaacgcaat agttgtcaga ggtaaaatca gtaatttacc tgaagattta gaacagatca
    51481 aaatttctaa attcatcaat gaattacctg gatataatgc gcaagtattg acttttggat
    51541 ttatgatcgg atttttgatc gttattgcgg ctattgtgat cgggattttc atttatgtac
    51601 tgacgatgca aaagattaat atctttggtg taatgaaagc acaagggatc acaggaggat
    51661 ttattgcgcg ttctgtagtg gcacaaacat tcattttatc atttgttggt attcttcttg
    51721 gtctattagg aacagtggga acatcccttg ttctacctga tgcggttcca ttccaaagca
    51781 attggctgtt ttttggcgtc attagcttgt tgatgctggt agtagctgtg ttaggcgcac
    51841 tattttctgt tcggacaatc gtaaaaatcg atccgttgaa ggcaattgga taagaaggag
    51901 gaagagcatg aaagcaatag aatttaaaga agtagaaaaa agtttccaag atggcgacca
    51961 agtagttaaa gcattgaaag aaacaaccat gagtatcgat aaaggggaat ttgttgcaat
    52021 catcggtcct tctggttcag gtaaaagtac ttttttgact ttggcaggcg gattgcagac
    52081 gcctagcagt ggctctgtat ttatcaatga tcaagaattc agtaatcaaa aagaaagtga
    52141 acgcgttaaa ctacgtttta aagaaattgg ctttattttg caagcttcca atctggttcc
    52201 ttttctgaca gtaaaaaagc agttattatt agtagataag atcaaacatg aacatcgtca
    52261 aaaagaagca aaagaattat ttgagcagct tggcgtggat aagttgatca acaagtatcc
    52321 agaagaacta tctggtggag aacggcaaag ggtcgcaatc gctcgtgcat tgtacaatga
    52381 tccgtccatt attctagcag atgaaccaac tgctagtttg gattcagaaa aggcacgaga
    52441 agtagtcgat atcttggcaa aagaatcaaa agacaaaaat aaagcaacga tcatggttac
    52501 tcacgataca cggctgattg acaaatgcga tagaatattt atgatggaag atggtgtatt
    52561 gaaagaaaaa gaataaccaa aaagcaggtg gaaaaatggt ccatcgatac aacaaagata
    52621 cacagcaaaa aattttgaaa gaagcgactg acttgtttat gtccaaggga tatctcggca
    52681 cttcaacaag agagatcgca caaaaagttg ggatcaccca acccaatctc tatcattatt
    52741 tcggtgataa agaaaaacta tatacggcag ttttagaaaa ccacttaaaa gatgttggaa
    52801 aagctttgag agaaatcgtt caaacaagcg aaacgggatt tcaagtaacc ttgacaaaaa
    52861 tggcgcagtt tttgattgag acacatctgg tcgatttgtt tctgatgctt cacgatcttg
    52921 aaagcaatct ttcaaaggaa acaagagatc atcttttctt tctatggaag aaaaattatc
    52981 gtgaaccttt tgaagaaatc ttttcagcaa accaatctgt gctaagaaat gggatttcaa
    53041 aagaaatcgc agcaaggcat tttttcttag tgttagcacc ttacatcact cggtcgaaaa
    53101 gacctgtgga agaaccgcta aatgtggcgc aattgatcga tttatatttg aatggtgtat
    53161 taggagaagc gtaaagctgt tatataggga gaaaaatagt taggtgaaga agcaagatat
    53221 gacgaagatc gttatatctt gtttttttta tataggtagt ttttcataaa tacaaatttg
    53281 ttattctctc atgattatca gggtatattt ttatttatta tgtcggtgtt ccaggaagtg
    53341 ttttaattta ataacgaaga aattaattgt ttgtagaatg aaggaaacta tttattgggt
    53401 agatgaatca ccacgaatag tcaaaaggag atttcaggat atgccaaaaa tgaaaaaaat
    53461 cattttagca gtaatgttat tttctacggt tatatctttt acagcccctt ttttgcgtac
    53521 ttaagctgat tttaagtttt gacccttagt ctggatctac gaggtgagag tcaagaatga
    53581 aaaaaataat tggagctttt gtatttgcaa tcattatcat tattatctgt tttcaaatag
    53641 atgtttttgg tcaaaaaaag atagttggac aaacggtcag cagtacgaac agtacggtta
    53701 caaagacaaa ggaatcattt gatgatacag aacaagagac attaatcaaa atcggaaaaa
    53761 atgaccgtac actatataca gatgactcgc taactacccc acttgcaact ataaacggcg
    53821 gagagctggc ggagtttctt tctgaaacaa aaaatgctta tcagatcaag acaaatgatg
    53881 gctatactgg atatttagcc ctcgaagatg gaaccaaagt cacaaagaat atacaaacaa
    53941 aaccggaaga gctatctgat gcagtgattg tattagatcc tgggcatggc ggaaatgata
    54001 ctggggcatt aagcaatgat gaacaaacag aagaaaaaga tataacatta agtacagcca
    54061 taaaagtaaa aaaggcgcta gaggatgctg gagcaacggt ttatttgacc catactacag
    54121 atgaattagt acagcttgga gatatatgcg actacagtga agaaaaaaag gcagatgtct
    54181 ttatcagttt acacgcagac tctacggaat atgcgaatga agcaactgga atcacgacat
    54241 attattacta tggacaagag gaaacattag cacagacaat tgctgactcc ttcactgatc
    54301 tgcctctgga ttcaagagga atctccactg ggaactatca agttcttcga gaaaatcttc
    54361 aaccttctat tttaatcgag atgggttata tgaataatga tagtgattta aaggaattag
    54421 taacagacag ttatcagcag cagattgctg caagtttgac acaagcattg accacttatt
    54481 ttcagtaata aataagccca gccaaacaaa aatagctcct catatttttc gtttggccgg
    54541 gcttattatc gcagatgcaa gcttttgaac accgtttaag gaagaggttg tgagcctgcc
    54601 gtttaactcc gcgtcacaag gagcaatttc aaaaaacagc ttctcatgtt tgatgactat
    54661 tgtgacttgt gaccgaggag ttggcatgag aacaccgttt attcggaaca agggactgtg
    54721 acatgacttt tgtcacagtt ccattatttt tttagcagct tcaaagcttt ttctgtattg
    54781 gcaaaatgaa gtttggcata tttttcaagc ataggcatgc cgcctttctc caatagtttt
    54841 gccgctactt ggtcagattt cgttccagct cctgatggaa gggtgattcc agcttcagct
    54901 gatgctttgt gtaactcttc caaaaagctg gcacgactga tgatagaagc agcagcaaca
    54961 gctaaatgat attgttctcc tttagtaacg aagtacagtt tttcttgtaa ttgatttttt
    55021 tctaaacgcg catatttttt aaaatttgct tccggcgtaa actgatcgat caaaatcgct
    55081 tctggttttt ctggctcgat tttttttagc agcaaatgga tcgcttgatt gtgcaaagcg
    55141 actttcatcc gaacggcatt gtattttggt tggatctcat tgtatttttc tggagataag
    55201 acaagcagtt tataggggat ggtttttttt aagatgtcag caagctggat gatttggcta
    55261 tcttttaact cttttgaatc tctaacacca agtttacgta attctgcaag ctgatcacgt
    55321 ttcacataag cagcacatac tgttagcgga ccaaaatagc tgccatttcc gacctcatca
    55381 ctacctaaaa cggataattg actgatattt tttggcaaag aagaggctgt ttttgctggc
    55441 ttggcttgtt tatcctgtgc ctccccccat ttatcagctt ctattgctgc attcgtacct
    55501 tgaaacatca cttttccgga tgtataagcg gtaatggtcg tcccgtcttt ttttgcagca
    55561 aagctagtat aaggaatctg tttatttaac aaataagagc gatagtatgc tttcatttga
    55621 ctaagttggt cgtttgttgc tttgataatg acgttgctca taaaattctc ctcgttttta
    55681 tacataaaac tataccgcaa ctcacgactt ttcgttttct aagagattgc gagacatagc
    55741 atttttttaa agtttatcat ataatagtta agtatgtgaa aaatatttgt ggagaacggt
    55801 gaaagaacca acttcatggt acactaaata aaactttcat caaataggag gaaatgattc
    55861 gtatggcgca cgaaaaaaca cgctacaaag cagtgattgc caaccaaaca tatactatta
    55921 tcggacggga aaccaagcat catatggata tcgtaacgaa gctgatcaat gaacagttag
    55981 cagaattgaa acaattatca ccacaaatgg ataatgaaca agcagcaatc ttgatggctg
    56041 tcaatgcgct ttcggatcaa ttgaagaaac aagaaagaat cttggagctg gaagaagaaa
    56101 cagcagaatt aaagaaaaaa atgatcaaat ttacagagct tgaaaatcgt gtgaaacgca
    56161 ttgaagcaat cgagaacgaa gctcgggaag tattgaaaga aaatggtcaa gcagatcata
    56221 ccattaaaaa tcatgtggaa gcacaacaga ttttaaacga gaaacgaaaa ggacaaatta
    56281 aacaaaaatc ttctaattaa gatcctttta tcaaaataag aaaaatttaa aaaagttaga
    56341 agagaaagga acgtagcatg ctgagtttgc tgattttatt tttattgcta attgcgtttt
    56401 tttctggagc acgtcgcggg tttgctttgc aaatcatatt cgcgattgga tatgtattgt
    56461 catttattgc tgcccagcat ttttacaaac cattagcaag tcatttggaa ttatacattc
    56521 catacccagc tgtcacccca acatcaaagt tagcattttt tgatcaggta tttgcttttc
    56581 acctagatga agctttttat gcaggaactg cttttctgat tattttgcta attggctggc
    56641 tgcttacccg atttgtgggg gtttttgtcc atggattgac gtatgtgccg atcttgagac
    56701 aggtagactg gattgcagga ggcatcctgt cactaatcat ggcttacgtt actatatttt
    56761 tgattttgca gttacttgcc tttgttccat tagatgtggt ccaaaatcaa ttcggcgagc
    56821 atagtttcgc tcgttttatc gttgagagaa cgccatttct taccaacaag atgtatgagc
    56881 tttgggtaac gaatattttg aattaaggaa aatagtgctg gaaaatattt cgttttttgt
    56941 acagagtagt ttatttaaga aggctgcgta gcgtatgtcc ggcacagctc ttttttcata
    57001 gtgaaagata aggtgataaa atgaataacc gaatccttga aacattggaa tttgaaaaag
    57061 tcaaacagat ggtcagacaa tttgtagtga ctgcacaagg aaaagaagaa ctggcagaat
    57121 tggtaccagt gagtgagaaa caaacgatca caaactggct tcaagaaact gaggatggat
    57181 tgaaagtgca acgtctgcga ggcgggatcc ctatacctaa acttgaaaat atccgtcccc
    57241 atatgaaacg gatcgagatc ggagcagact tgaatggagt ggagcttgca caagtttcca
    57301 gagtattgtc tacgacaagc gaattgaatc gtttcattga tgatctttct gacagtgaaa
    57361 tcgaatttgc acgtttgtat atgtgggcag atcagttagt cacgatccct gttttgagcc
    57421 gccgtttaaa ggaagcaatc gatgaagacg gacgcgtgac tgatgacgct tctcctgagt
    57481 taaagagcat aagacagaac attcggcgaa gtgaacaagc tgttcgtgaa cagttagatg
    57541 ggatcgtccg tgggaaaaat gcaaagtatt taagtgatgc gatcatcacc atgcgaaatg
    57601 accgctacgt tatcccagtc aaacaagaat accgcggtgt atttggcggt gtagtccacg
    57661 atcaaagtgc ttcaggacag actttattta ttgaaccaaa acaagtggtg gatttgaata
    57721 atcgtttgcg tcaataccaa atcgctgaac gaaatgagat tcaacgtatt ttaagtgaac
    57781 tttctgctga acttgttccc catcgtcaag aaatcatcca caatgcttat gtgattggta
    57841 aaatggatct gatgaatgca aaagcacgat ttggtaaaga agtaaaagcc atcgtgccgg
    57901 gaatcagtga agacaatcat gtcgtcttga aacaagcaag acatccactg atcgatcagg
    57961 aaaaagtagt ttctaatgac atcacaatcg gaaaagacta tcaagccatc gtcattacag
    58021 gacctaacac aggtgggaaa acgatcacgt tgaagacttt aggtctgtta caactgatgg
    58081 ggcaagcagg attaccgatt cctgcaggtg aagaaagtca aatcggtatt tttgaggaag
    58141 tatttgcgga tataggagac gaacagtcga ttgagcaaag tctatcgacc ttttcttctc
    58201 atatgacgaa cactgtagat attttatcaa aagtcaatga aaaaagtctg gtattatttg
    58261 acgagctcgg tgcaggaaca gatccgcaag aaggtgctgc tctagcaatc gcaatcttag
    58321 atgatcttgg taaaaagtct gcttatgtga tggcaacaac gcattatcct gaattgaaag
    58381 tttatggata caatcgggca aatacgatta atgccagcat ggagttcgat gtggatacac
    58441 taagtccaac gtatcgtttg ctgattggcg ttcctggacg aagcaatgcg tttgaaatct
    58501 ctagccgatt aggtcttgat acagaagtta ttgatgaagc gaagcagttg atgaatgatg
    58561 agagccaaga tttaaacgaa atgatcacag atttagagaa tcgccggaaa atggcagaga
    58621 ccgaatatct ggaaatgcgt cattttgttt ctgaggcaca agaacttcac gatgatttga
    58681 aagaagctta cagctatttc tttgaagaac gtgaaaaaga aatggaaaaa gcaaagaaaa
    58741 aagcaaacga agtcgtgtca gaggcggaag aaaaagcaga aaaaatcatt gctgatattc
    58801 gtaaaatgca acagcagatt gggcaaggaa atgtgaaaga gcatcagttg atcgatgcaa
    58861 agacccaatt agcaaatcta catcaagaag aaactttgaa gaaaaataaa gtattgaaga
    58921 aggcgaaaga acaaaaaacg ttgaaaccgg gagacgaagt gttggttacg acttacggcc
    58981 aaagagggac gcttttacgt aaaaacggga atcagtggca agtagaaatc ggtatattaa
    59041 aaatgaatgt gtccgaagac gagctgacgc ctgttgctcc tcaaaaagag ccgacacaac
    59101 gagttatcca tgctgtacga tctgaatcta gtagtcacgt gccgaatcaa ttggaccttc
    59161 gaggaaaacg atacgaagaa gcgctaagtg aggtagatca atatttggat tctgccattc
    59221 tagctggtta tcctcaagtg actattgtcc acggaaaagg aacaggcgca cttcgcaagg
    59281 gaattactga ttatcttaaa aaccatcgga gcgtcaaaag ctttgagttt gcaccggcaa
    59341 accaaggcgg aaatggtgcg acaattgtta aatttaagta aagcttacta aaggtaagca
    59401 gatggttcgc tatccaagta tagaaatgct atactaatca tagattttaa aaatggaggt
    59461 ctttgatatg tcacaagtaa ttacagataa gacatttaat gaagaaacag ataaaggact
    59521 tgtattgatt gatttttggg caacttggtg tggtccatgt cgtatgcaag caccgatttt
    59581 ggatcagttg gaacaagaat atgatgaaga agaattcaga attgctaaaa tggatgtgga
    59641 tgaaaatcca gaaactcctc aacaattcgg tatcatgagc attccaacat taatgttgaa
    59701 aaaagatggt caagtagtag aaaaagctgt tggtgttcat tcaaaagaac aactacgtca
    59761 aatgatcgat caatatttat aaaaacttac agcaaaaata agctgagggt gggactgaat
    59821 ccagttccgt cctcggtttt tttgcggttg agttaaggtt attcaaatta atattttttg
    59881 agtataatta cgttgtcagg ctggattgtt tttttgacag acatgctata ataactttaa
    59941 ttgaatatga aggggagtac cagatgaacg aacgaatcaa aaacaaatta gctttacttc
    60001 ctgatcagcc cggctgttac ttgatgaaag ataaaaatgg aacgatcatt tatgtcggca
    60061 aagccaaaat attaaaaaat cgtgtccgct catattttac tggcagccat aatacgaaaa
    60121 cggaacggct tgttagtgaa atcgaagact ttgaatacat cgttacagaa tcgaatatcg
    60181 aagcattgct cttagagatc aatctgataa agaaaaatga tcctaaatac aacattatgt
    60241 taaaggatga taaaacctat cctttcctta agataacgaa tgaaaaatat ccccgtttgg
    60301 tgattactcg taaagtacta aaagacaaag cactgtattt tggaccatat cccgatgtcg
    60361 gtgcggcgaa tgagacaaag aagatcctcg atcgattatt tcctctgaga aaatgcaaac
    60421 ctagtcagac gaaggagcct tgtctttact atcatttggg acaatgtctg tgtccttatt
    60481 atttcgacgt agatccgaaa gtctatacga aaatcgttga tgaagtgaaa aagtttttaa
    60541 acggaggaca cgaaaaaatc gagtcagaga tccatcagaa aatggaaaaa gctgctgaaa
    60601 acatggagtt tgaaaaagct gcagaatacc gagaccagat ccgtgccatt gagacaatca
    60661 tgactcgcca aaaaatgaca aatactgatt tactggatcg agatgtattt ggttatgcga
    60721 ttgacaaagg atggatgtgt gtccaagtgt ttttcgtaag acaaggaaag ctaattgaac
    60781 gagatgtttc aatgtttcct ttctataacg aagcagaaga agatttcttg acttacctcg
    60841 gtcagtttta tcaggaaaat gagcatttca ttcctaaaga agtcttgatt cctgatacga
    60901 tcgacaagcc cagtgtagaa gctttgttag ctacgaaagt gctgcaacca aaacgaggag
    60961 aaaagaaaaa attagttgaa ttggcgaata agaatgcctc agttgctttg aatgaacggt
    61021 ttgatctgat tgccagaaaa caggaacgga cgatcggagc agttgaacgt ttaggaaacg
    61081 cgatgaatat cccgacccca atacgtatcg agtcttttga taactctaat atcatgggga
    61141 cgaatcctgt ggctgcgatg gtcgtattca ttgatggaaa accggcaaga aaagaatatc
    61201 ggaaatataa aataaaaaca gtcaacggac cggatgatta tgcatcaatg agagaagtca
    61261 tctatcgcag atattcacga gtgattcgcg aagagttgcc tttacctgat ttgatcttga
    61321 tcgatggagg aaaaggacaa gtagatgtgg caaaagatgt cttagaaaat caattaggaa
    61381 tcgatattcc tattgctggc atggcaaaaa acgataaaca taaaacaaat gagttgctat
    61441 tcggtataga tttggctgta gtaccgcttg agcgaaattc accagagttt ttcttactcc
    61501 agcgaatcca agatgaagtc catcgattcg caatcacttt ccatcggcag ctacgcagta
    61561 aaaacagttt tgcttcccga ttagatgaaa ttgaagggtt aggaccaaaa cgaaaaaaaa
    61621 tgctgcttaa agagttcaaa tcgttgaaaa atatcacagc agccacgaca gaagaattac
    61681 aagaaatcgg actgccgaaa aatgtcgcac aaaacgtatt tgataaatta catcaggaat
    61741 gaggaaaggg cactttacaa agaaagtaaa gtgtcctatc attttatgta caacaaaaag
    61801 agcgtttacg ttttgttggt aaataataaa tcgcttacgt ctggtgtcta aggatatatg
    61861 tgatttcttg aagaaggagt gaagaaatgt tagaagtcaa ggatcttgtt aaaacttttg
    61921 ggaactacac agctgtcgat catgtctctt tccaaatccc cgatggaaaa atcatggggc
    61981 taattggcca aaacggggct gggaagacaa cgacttttcg tttgatcttg gattttttga
    62041 cacaagacca aggagaagtg ttatggaatg gccatcatct tggggagaaa gattatgatg
    62101 tcatcggtta tcttccggag gaacggggac tttatccgaa agtaacgatt caagaccaac
    62161 tgctttattt tgcagaactt agagggaaat caagaaaaga gattgaacca aaaatcgatt
    62221 tttggatgga aaaatttcag gtaaaaggga aaaagacgga taaagtaaaa tctttgtcta
    62281 aaggaaatca gcaaaaagtc cagctgatcg ccacgttaat ccatgaacct aaattgatca
    62341 ttttggatga gccattcagc gggttagatc cggtaaatgc tgaattgcta aaagatggaa
    62401 tattggaatt gaaaaaacat ggttcatgtg tcattttttc tagccacaat atggataatg
    62461 tagaaaaaat ctgcgatcat ttgatcatgt tgcgaaacgg aaaaatggtt ttgaatggaa
    62521 aagtacatga gattcgtgaa tcatttggcc gtacgaagtt attcttggaa tctggtttaa
    62581 gccaacagga agtagaagaa atcgaaggcg tgaaaaaagt gatccttcat gaagacaata
    62641 cgttagagat taccttagaa gatcctgaag ctgggaaaga aatctttact cgtgcgactc
    62701 agttcggcta cattcctatg tttaaccagc aaccgccaac tttggaagag attttcaaat
    62761 tgaaagcagg tgaaatcgat gcgtaagttt tggattatta ccaaagatgt ctatttaaaa
    62821 aatgttaagt cgatttcttt cttgatcatg atattagtcc cttttatcat gctgggtatc
    62881 atttatgtag caggaaactt tgctcaacaa aatagtgatg tcaataaaat cggcgtattg
    62941 gctgataatg agcaaatcag tcagcaaatg agccaagtca aaacagatga ttttgagttc
    63001 aaagcagttg attctgaaga aaaagcacaa aaagagcttt cggaagaaaa aatcgatgcg
    63061 tatttagtag tctcaactga gaatgataag ataaatggga tgctttatag cgaaaattca
    63121 ttaggacaaa gtacacaact actgatacaa caacaactga ctggcttgca atcgatgctt
    63181 cgagcaagtc aattaggcat ttcaccagaa gaagtagcta gcttgagcca acaagcaagt
    63241 ttgactcgac aaaaagtcaa ttttgattca aaaggaaaaa tgacagttgg agaagataac
    63301 tcgacagtcc aatatgtcgt aagttatgta gcaacgattg tcttgttcat tattattttg
    63361 acgtatgcgc agatcattgc acaagagatc gcttctgaaa aaggcacgcg gatcatggaa
    63421 gtgatcctgt ccagtacgac tgcacaaaag catttttacg gaaaactaac aggtgtttta
    63481 cttgttgcat taacgcaaat ggcattatac ggtattattt ttggtatagg atacagtcaa
    63541 ttcaaagata tggaaatggt caaaaatata ttagacggta tctcattgga taacttgatt
    63601 ggaccattct tgtggtattc tcttctattc atgatctttg gcattttgat tttttctgtt
    63661 ttagcagctt tatgtggctc tttggtcaac aaagcagaag atacagcaaa agcaattttg
    63721 ccagtgactt atctatctct aggcggatat atgcttggat tgatactagg agcttcagat
    63781 ccaaacaata tcgttattcg gatcacttcg tatattccat tcttatcttc atatattatg
    63841 ccggttcgct tagcaaatga gacagtcggt atgggtggag cattgatttc cttgttggta
    63901 cttgtagccg taacattctt attgatgatc ttgtctgcaa acatgtacaa atcgaatgta
    63961 ctcgtgtata gcgaaggcgg attatggagt tcattgaaac aatcgatttc aattatgaga
    64021 aatgaacgaa aaaaagcata aaatatagaa aaatatagaa ggaagctgga catttattgt
    64081 tcccagcttc ttttttgtat agacctattt ctattttttt attatattgg atatatattc
    64141 attgaaaata gagcataaca actttataat gttgagtata ccaatttttg gaggcgtttt
    64201 aatggaccgc tatttagatt tactttcaga gaagttccct acaacggaag atgtcatcac
    64261 ggaaatcatc aatctcgaag caattttgca gcttccaaaa ggaacagagt tatttttgag
    64321 cgatatacat ggcgaatttc ctgcttttga tcatattctg cgtatcggtt caggaaatct
    64381 taaagaaaag atcaaagacc ttttctctga acaaatgacg gaaacggaga tcagccaatt
    64441 cactattttt acggcttatc cagaatatgt gttgacgact gattggtaca aaaaacaaga
    64501 taaatcccag ctgatccatc gtttgatcga tcttttacgg tttacgacag tcaaatacac
    64561 tcgatcaaaa gttcgaaaag gattgccgaa agaatatagc tatatcattg aggaactctt
    64621 gtatatcgat gatcgtatca acgggaaaaa agactatgta aaaaaaatca ttgaacaact
    64681 tgtcttgatg aaggaagaag aaaaattttt aacaaaactt gcgcagacga tccaaaaatc
    64741 tgtcatcgat catttgcata tcgtgggtga tatttttgat cgaggaactc aagcagccaa
    64801 agtaatggat cgaatcatgg atttttcctc tgtagatatc cagtggggga atcatgatat
    64861 tttgtggatt ggtgcgtatt gcggctctga ggcatgttta ttgacgcttt tacggattgc
    64921 cgcacgctac aactatttat ttgaattaga gaaagaatat ggattaaatt tacgtccatt
    64981 attttctttt gcccatcaaa cctatcagaa gaatccagta tttaccccta aaaacaggaa
    65041 agatctatct gaaagagagc aagaagaatt agaaaagatc catcaagcac tttctatcct
    65101 ccaattcaaa tcagaacatc agttgttgaa tcgacgacct gaatttaaaa tggacgatcg
    65161 taaattgttg gaaaaaatca actatgagga atcaacgatc gttttagaag gtcagctcta
    65221 tgagttgaaa gggacttgtt ttcaaacgat ccagccagat gatcctaaaa aattcttgga
    65281 agaggaacaa aaagtgatcg atagtttgat gtattcattc cagcactcgt taagaatgca
    65341 aaaacacatg acgtttttga tcgaaaaagg gggaatgtat ctcacgaaca atcagcatgt
    65401 actgttccat ggctgtatac ctgtagatga aaaggggcag ctcttagcat ttgaattaga
    65461 ccaatcttat cgcggaaaag aactgctggg attttttgaa aaacagataa ctgaaagcgc
    65521 aaaagatttg actgcaaatg aagatttggc gaccgatttg atttggtatg cgtggagcgg
    65581 gccattttcg cctttattcg gcaagagtaa aatggcaact tttgagcgct attttctcac
    65641 agagcctcat acgcacgtcg aaaaaagcaa tccctattat cacttgcgag atgaagagtg
    65701 gttcagtgaa aaaattttgg cagaattcga tgcaaaagaa gaaggttcag caatcatcaa
    65761 tggacacacg ccagtaaaag taaaaaaagg agagtcaccg atcaaagcaa acggaaaagc
    65821 atttgttatt gacggaggtc tatccaaagc ttatcaaaaa acaaccggga ttgctggcta
    65881 ctcattacta tgcaattctt acggtttcca aatcgtgaca cattatccgt tcttgcctat
    65941 tgaacaacaa tttgcaaaaa aatctgatca aacgaatgta aaaaaagtga tcgagcagca
    66001 gctcccacgc aaacttaatc ggaatacgac aaaaggaatg gaattacagc aacagattac
    66061 tcaactccaa aggctgttgg attatcgaaa ggacgattga gaaaaatgct agccaacatt
    66121 gctcaataga ctaaaaagcg actgcaacaa aaggcgtgtc gcagtctcct tcggaattag
    66181 ctcaaaaaac ggtaaaatat tagaagctat ttttctgttt atttctctaa tactcaggtc
    66241 agggcgctga tttcacgacc tcttccttaa acggtgttct cctgccaact cctcggtcac
    66301 aagtcacaat atccaacaaa catgagaagc tgttttttga aattgctcct tgtgactcag
    66361 agttgaacgg caggctcacg acctaatcag aaaaacgatt aaaattcatt cacaaagaaa
    66421 tcgaataaac gctgttcaga tgaatctaca cgatgagaaa gttccggatg ccattggaca
    66481 ccaaggattt tgtgcatatt atctttactt tggactgctt caatgagtcc atcgttggaa
    66541 aaggcgatgg cttttaacaa aggagaaaga tctttgactg cctgatgatg ataggaattc
    66601 acaaagtatg aatcagggag aaggtcactt aataaactgt ccgaaacgat tttgacttcg
    66661 tgagttgcaa actgcggggc agtgggctgt tgttcgtgtt ttacggacca ttttggatat
    66721 aatgaaagat cttgataaag tgttccctcc aacacgacat tcaatagttg aagtcctcgg
    66781 cagactgcaa aaatcggttt tctttgtttc aatgcttcca agatcaatgc ctgttcgaat
    66841 tggtctcgtt gaatatttgt ttccgtcagt tttggatgag ggtcttccat gtaaagttgc
    66901 ggactaacat cctgaccgcc tgcaagaatg agtttgtcga ttttctcaat tagttgaggc
    66961 gctgaatctg gagacatgac tggcagaata agaggtaatc cttgagcatc taaaactgca
    67021 tccacaaatc cctgcggtgt atagcttact tgatttcctt ggaaagtatc tgtcgctcga
    67081 atcagttgat tcccggcaat gccgatgatt ggtttcattt ttattccccc taaagtagac
    67141 taattgtaac aaggatttaa aaaaatttaa actatgtaag acttgcccct atacttatct
    67201 gttcttgctg tgttactatc tgtaaagaga attttcgtgt gaaattcatg acgatagttg
    67261 aaaatattgc ttaatttgtt ataataaaaa gtaagcagaa ataaaaaggt tgggcgtaag
    67321 cttcaaggat ctagttcttc aaggggtgag aaggacattt tattgaaggg gcctgcctat
    67381 actaagttat ctttagaggt acatactttc aatgaaaaaa gaaagcatgt acctcttttt
    67441 taaatcgaaa ggaagtgaag caagtgttag aagctttgga acaaatccga aaagcagaag
    67501 aagaaaatga gaagcgtgct cgaaccctac ggcagcagtt gaagacctat gcagaagaaa
    67561 aagagcaaga attggagata atccaaacga acagtcggca acagctgaaa cagttggtag
    67621 aagaaaaaga acaattcgaa aagcaagaat tagaaaaaga aaaaatgaaa ttgaaagcag
    67681 aagcagacaa ggtgcaagca actttgaaag accaatatca aaagcatcag agtcaagcaa
    67741 tcggtgcaat cattgaaagg gtgaaagaaa cttatggccg tcactaagat ggaaaaagtg
    67801 accctcattt cagataaaag aaatcaggag aggattttac aagcagtaca aggaatccaa
    67861 aatgttgaaa tccgggatct gtatcaaaat agaacaaaca accagtgggt agaaaaatat
    67921 tttccagata ccacgattat tgataaagaa gcaaaattaa gcgctttagg caatcggctg
    67981 aaagacatcc aagaagctat ccaattcata caacaccacg gcgatagccg tcaaaagaaa
    68041 ctccatttga aacgtcaaga actttcctta caagacttgg aagcaaatta ttccgaagaa
    68101 aatttcatga ataaattaga agaggtcctt gatttaaaag aaaagtggga acagctaact
    68161 gaaaaacgtg atcgtttaga agaagaggaa gaatggcttc ttcattggca acagctggat
    68221 attgctccaa gtatgtatgc aagtaagacg accatttttg agatggggac tgtgagtgca
    68281 gcaaattttg aaagtttcaa ggaagaacta agtaagcttg atgacgttta tatggaagaa
    68341 atagattata cgccaaaaca agtttatctt tcgtatgttg ctttaaaaaa atcagttgct
    68401 gctatagaag aaattgctgg gaaatacggg ttcaataaag aaacgtatcc ttatgaacaa
    68461 aatcctaaag aaaaattgca agaaaccaaa cagcaattat ccattgttca cgagcagcaa
    68521 aaaaagataa cgacagcgtt aggtcagtgc agcggctata tccaagaatt tgaatgggta
    68581 gaagaagtca cacttgccgt tgcagaacgg gaaaaagtaa aagaacggtt tatccatgcc
    68641 acttatctga tcgttttgca aggttgggta gatgcagaag aaaaacagaa tttgatgcat
    68701 gtgttaaacg aaactgtatc agaagaagat atatacgtta gtttcgaaac accaaactca
    68761 gaagagattc agcaggaagt ccctactaaa ttgaaaaacc atccgcttat cgaacctttt
    68821 gaattgctga ctgaaatgta cagtctgcca aaatatgaag aagtagatcc aacgccttgg
    68881 atgacaccat tttatcttgt cttcttcggg atgatggtcg cagatgttgg ttacggattg
    68941 ctgatgctca ttgggacaat actagctcaa aaactatttg ttttaccccg cgggatgaaa
    69001 cgtttcgtaa aattctttga gattctctcg gtaccatcga tcatctgggg attgatctac
    69061 agttcatttt tcggacaggc attaccaaaa gaactatttg gtatccgctt gcctttccca
    69121 atcctatcta cgacggatga cgtcaatacg attttgattt tatccgtgat tttcggtctg
    69181 atacagatct tggttggatt attcgtggca gcaaaggaaa atatcaggag gaaagattac
    69241 ttgagtgctg tcagtgatgg ttttgcctgg caagggatcc tgattgggat cgttattgca
    69301 ttgattggtg tcatgttgat aaaaaataca gcatttgttt atcttggcgc ggggctatcg
    69361 atcattgctg ctttatgtat cttaatcgtg ccgattatcc aatcgccgtc taaagtcaag
    69421 ggtgctgcca aaggagcgta taatctttac ggattgactg gttatatcgg tgatttagtc
    69481 agttatacac gtttgatggc actaggtatt tcaggcggaa gtattggcgc ggcattcaat
    69541 atgctagttg ctttcatgcc gccagccgct cgattcagtg tagggatcct tttgatcatc
    69601 gctttacacg cactgaatat gtttttgaca ctgttaagtg cctatgtcca tggtgcacga
    69661 ttgcagtatg tcgaattttt tggaaaattt tatacaggag gcggacgtgc ctttgacccg
    69721 ctgaaaacgg cggaaaaata cgtcaacatc aatcataaga aaaaaaacaa taaataattg
    69781 gaggattttt atacaatgat ggattactta attagtcaaa atggtggaat ggtatttgca
    69841 gtattagcga tggcaacagc gacgattttt tcagggattg gttcagctaa aggtgttgga
    69901 atgacaggtg aggcagcagc agcgttaaca acaagtcaac ccgaaaaatt cggacaggct
    69961 ttgattctgc aattgcttcc aggtacgcaa gggttgtatg gattcgttat cgcctttttg
    70021 atttttatca acttaggaaa tgatatgtca gttgtacaag gattgaactt tctaggcgct
    70081 tctctgccga ttgcttttac aggtttgttt tcaggtatcg cccaagggaa agttgcagca
    70141 gcaggtatcc aaattttagc gaaaaaacct gaacatgcta caaaaggaat catttttgct
    70201 gcgatggttg aaacatatgc gattttaggt ttcgttattt ccttcctatt agtattgaat
    70261 gcctaagcat aaaggaggaa aagcagatga acgccattga aaaaatcatc tctcagatga
    70321 atgaagcagc agagcaagaa agagcggcgt tagagcaaga agagcgaatg aagatcgatc
    70381 aaaactttga acaaaaacgt acgcaaatcg aaacagaaca tcaaaaacaa aaagaaaaac
    70441 aaatcgaatt acttgaaaaa aaataccgtc agcttaggaa tcgccaacaa gtagaagtac
    70501 gacaagaaaa tttgaatgcg aagcaggaat ttttacgacg attgtttgca gatgcaatag
    70561 ctgaaatgga gaattgggat gaatctgaac aaatccagtt tatcaaaaat tcattgtatt
    70621 cattaccttt gacaggcaaa gtaacattca ttgctggaga aaaatcagca gcttatcttt
    70681 ctcagacatt gctggatgaa tggaacaatg aacttccctt tatgatggtt ttaagtgatg
    70741 aaactgttgc tgatcaagcg ggttttctga taaacgatca aggagttcag tataattttc
    70801 ttttcagcag ccttgtacaa gatatccaag gaacgatgag ttttgagatt gccaatcaat
    70861 tattcgaata aggagggatc agtgtatgga ataccacgaa ctaaatccct tgattcgcgg
    70921 aagagagctt gaacttttgt ccaatgagac atttgaacgg atgattcaaa caaattctgt
    70981 cgaagcactt ggtgaaatat tgaaatccac gatttacagt ccatatattt atgacggata
    71041 tgaatatgac ttcgaacaga atcttttaaa ggagcagagc cgtctatttc gctggttaaa
    71101 ggaatcagca ccggagcctg aaatcgtttg gatctatacg atgcgctata ctttccataa
    71161 tctgaaggtt ttgacaaaag ccgagatgac aaatcaaaat ctggaccatt tgtatatcga
    71221 cgatggattt tattcattag aaaccttgaa ggatgccatt catacgcaag tttcaaatga
    71281 actccctgaa agcattatgg acagtatacg agaagtacgt gattattttg aagagtctac
    71341 cattcttcag ggaattgacg tgatttatga tcgacagttt ttgacagagc agcgacggct
    71401 tgccgataag ctaggatatc aagaattgct gacagaagtc attgctttta ttgacttgac
    71461 caatatcaca acgatggctc gaggaatatt gcagaaaaga acatatgggt tcatgacgac
    71521 ggtactttcc agctcgggaa gtatcgaaaa agaagtattt ttgaactttg tagataaaga
    71581 tatggaagat tacacgaatt ttctattaga gacagattat gctgattttc tgcgccctgt
    71641 catccgtgag ggaaatcttg atctcgtaaa gcttgaacag ttgaaagatg attatctaag
    71701 ttcattgtat caagaagcac aaacccaggc tttcggacca ctgccactac tagccttttt
    71761 gaacgcaaaa gaggtagaaa gcaaaaacct tcgtttactg gttatcggca aaagaagcca
    71821 tttcgaacca gaaacaatca gaaagcgggt gagacaagtc tatgacgcat aagatcggtg
    71881 tagttggcga caaagattct gttttgccat tcaaattgtt tggctttgat gttcgttatg
    71941 gtacaaccaa gcaaaccgtt cgtcaggcaa ttgaagaaat ggcaaagaat gagtatggcg
    72001 tgatttatgt cacagagcaa tgtgcagcat tgagcccaga aacgatcgaa cgttacaagg
    72061 aacaaatgat acctgctatc gtattgattc ccaatcatca aggatcatta gggatagggc
    72121 tggaagaaat tcaaaaaaac gtagaaaaag cagtaggtca aaatatctta tagtatgaaa
    72181 aggagataga aattttgcaa attggaaaaa tcataaaagt ctccggacct cttgtaatgg
    72241 ctgagaacat gtctgatgcc agtatccaag acatgtgtct agtgggagat ctaggagtta
    72301 tcggagaaat tatcgagatg cgtggcgatg tggcgtctat tcaagtatat gaagagactt
    72361 ctggaattgg tccaggcgaa ccggttcgct ctactggtga agctttatct gttgaattag
    72421 gaccagggat catttcacaa atgtttgacg gaatccaacg gccattagat acctttatgg
    72481 aaatcacaca aagtaatttc ttagggcgcg gagttcaatt gcccgcattg gaccatgaga
    72541 aaaaatggtg gttcgaacca acagtagaag ccggagaaac ggtgagtgct ggagatgtta
    72601 tcgggatcgt agaagaaaca aaagttataa aacataaaat catggtgcca aatgggataa
    72661 aaggtacgat caaaacaatc gaaaaaggtt cattcactat tgatgaaaca gtatgtgtca
    72721 ttgaaaccga aaatggtgac aaaaatttga cgatgcttca aaaatggcca gtaagacgta
    72781 gtcggccaat caaagaaaaa ttaaacccgg atgcacccat gatcactgga cagcgagtga
    72841 ttgatacatt cttcccagtg acaaaaggag gagcagcagc tgtacctggt ccttttggtg
    72901 cagggaaaac agtcgttcag catcaaattg caaaatgggc cgatgtggac atggttgtct
    72961 atgtgggatg tggcgagcgt ggaaatgaga tgacggatgt tttaaatgaa ttccctgaat
    73021 tgattgaccc taatacagga gaatcgttga tggaacgtac ggtattgatt gctaatacat
    73081 caaacatgcc agtagcagct cgagaagctt ctatctatac gggaatcaca attgcggaat
    73141 atttccgtga catgggttat gacgttgcta tcatggcaga ctccacttca cgatgggcag
    73201 aagcacttcg tgagatgagc ggacgtttgg aagaaatgcc tggtgatgaa ggttatccag
    73261 cttatcttgg ttcacggctt gcggaatact atgaacgatc tggaagagtc attgcattag
    73321 gatcagaagg tcgcgaagga agtataaccg caatcagtgc tgtatcgccg tctggagggg
    73381 atatttcgga accagtcaca caaaatacat tgcgggtcgt aaaagtattc tggggtcttg
    73441 attccagttt agcccaaaaa agacattttc cttcgatcga ttggatacaa agctattctc
    73501 tttattcaac agaagtaggg aagtatatgg atcatatcct tcaagctgac tgggcatcca
    73561 tggtcaccga gggcatgcgt attttgcagg aagaacagca gctgaatgaa atcgtgcgtt
    73621 tggtagggat tgattccctt tcagataatg accgtctgac attagaagtg gcaaaatcca
    73681 ttcgtgaaga ttatttgcag caaaatgctt ttgatgatgt cgatacattc acttcaagag
    73741 agaaacaatt caaaatgttg aagatgatct tgacctttgg tgaagaagga cgccgtgcgt
    73801 tgtcgttagg tgcttattta agtgagatca tggacggtac cgtatcgatt cgtgaaagga
    73861 tcggacgaag caaatatatc ccggaaacag aattagaaaa actagatcaa attattggtg
    73921 aaatcaagca aacgatgcaa acgatcgttt cagaaggagg catgagcaat gattaaagaa
    73981 tatcgtacga tcggtgaagt cgtcggtcca ttgatggcgg ttgaaaaagt tgctggtgtc
    74041 aaatatgaag aattaatcga agtccgtatg caaaatggcg agattcgtcg tggacaagta
    74101 ttggaagtcc aagaagataa agcaatggtc caaatattcg aaggaacaag tggtatcaat
    74161 ttacgtgact cttctgtacg atttttaggc catcctttag aactaggtgt atcggaagac
    74221 atgatcggtc gagtattcga tggtttggga cgaccgaaag ataacggacc agagatcctg
    74281 cctgaaaagc atttggatat taacggagaa gtaatcaatc cagtagctcg ggattatcca
    74341 gatgagttta tccaaacagg tatctctgca atcgatcatt tgaatacatt agttcgtggg
    74401 caaaaattac cagtattttc tggctctggt cttcctcata aagaattagc tgctcagatc
    74461 gcgcgacaag caacggtact cgattcatca gatgatttcg ccgtagtctt tgctgctatt
    74521 ggaatcactt ttgaagaagc agaatttttc atggaagatt ttcgtcaaac gggcgcaatc
    74581 gaccgttctg tcatgtttat gaatttagca aacgaccctg caatcgagcg tatcgctact
    74641 cctcgtatgg ctttgactgc tgcagaatat cttgcttatg aaaagggaat gcatgttttg
    74701 gttatcatga cagacatgac caactatgca gaggcattgc gagagatttc tgcagcacgg
    74761 cgagaagttc caggaagaag aggatatcct gggtatcttt acacgaactt agctacttta
    74821 ttcgaacgag caggaagaat ccgcggacta aaaggatcgg ttactcaaat tccgattcta
    74881 acaatgccag aagacgataa aactcatcca atccctgact tgactggtta tattacagaa
    74941 ggacagatca tcttgactag agagctttac aagagtggga ttcagccacc aattgatgta
    75001 ctcccgtctc tttcgcggtt aaaagataag ggaactggac ccggaaagac aagagaagac
    75061 catgcagcta cgatgaatca gctttttgca gcctatgcac aaggaaaaca ggcaaaagaa
    75121 ttggccgtag ttttaggtga atctgcttta tctgatgtag acaagatcta tgcgaagttt
    75181 gctgagcggt ttgaaaaaga atatgtcaat caaggattct acacgaaccg ttcgattact
    75241 gaaacacttg atctagggtg ggaactgcta tcgatgttgc caagaaccga attaaaacga
    75301 atcaaagacg acatgctgga caaatatctg ccagaaggga agtgagttct gatggcacga
    75361 ttgaatgtga atccgacccg catggaattg actcgattga aaaaacagtt gacaactgcc
    75421 acaagagggc ataaattatt aaaagataag caagatgaac tgatgcgtca attcatcctg
    75481 ttgattcgaa agaacaacca gctgcgtcaa gaaatggaag agtctatgac agaagcaatg
    75541 tctgattttg tattggcaaa tgcttcgatc acggagcctt tcatcgaaga attatttgtt
    75601 ttgccggcgg aaaacgttga tttgtctatc gtagacaaaa atatcatgag tgtaaaagta
    75661 cctgtgatga attttgaata tgatgaacag ctgacagaca cacctttgga atacgggtat
    75721 ttgaattcca gtgccgaact ggatcggtca atcgatcggt ttactaccct gcttccaaaa
    75781 cttttggaac tgacagaaat cgaaaaaact tgtcaactga tggcgagtga aatcgaaaag
    75841 acacgtcggc gagtcaatgc attagaatat atgacgatcc ctcaattaga agaaacgatc
    75901 tattatattc gtatgaagct ggaagaaaac gagcgcgcag aagtaacaag gttgatcaaa
    75961 gtaaaaaata tgggtaccac tgactaagtg gtatcctttt ttaaaagagg aaaacgatga
    76021 ttaaacaaag caaacaaata aagaaacgct tgccggctgt tcagcttctc gcattaggat
    76081 tttttctcct gattttagtt ggcggcggcc tacttaccct accatttttt agtaatagtg
    76141 ggcatgggac aaattttatc gatgcgcttt tcactgcaac ttctgctgtc tgtgtgacgg
    76201 gattgacaac attgaataca gcagagcatt ggaacagtgc tggtcaattt ttgatcatgc
    76261 ttttgattga gatcggcggt cttggtttta tgatggttcc gattctatgc tttgcattga
    76321 taaagaagaa agtcagtctc agcacacgta ttatattaaa agaagcgctg aatctagaag
    76381 aagtatcagg tgtgatgaag ctcatgcttt acatcctgaa attggccttt gtgatccaac
    76441 tgattggtac ggttgcttta tcttttgtat tcgtgcctga atttggctgg ttgaaaggta
    76501 tctggtacag tttgttccat gcaatctcta gtttttgtaa tgcagggttt gatttgttag
    76561 gagacagttt agccaatcac cagcaaaatg tttatttgat catggtggta tctgctttga
    76621 tcatttctgg tgggttaggc ttcatcgtat ggcgtgattt actggaatat catcagaaaa
    76681 agaagataac gattcattca aaaatcgcat taaccgttac aggtaccctt ttattaggcg
    76741 gattcgttgt gttctttttc acagagcgca atggggaaac gctagtggaa gggaatatgt
    76801 ttcaacgatt ggcaaacacc ttttttatga gtgtgacacc tagaacggct ggatattatt
    76861 cagttgatta cctccatatg agccatgcag gtctgatttt aacgatgttt ttgatgtaca
    76921 tcggtggaac atctgggtcg acggccggcg gattgaaaac aactacgtta ggtgtgttgc
    76981 tgatccagat gcgttcgatg cttaaaggac gtacgagagc ggaagcattt ggccgtacca
    77041 tccgacaagg cgcagtgttg cgggcactta ctttattttt tgttacgttg acgttgtgtg
    77101 tagtcgccat catgatttta tcggtgactg aaacgatacc taaaacttct ggcatcgaat
    77161 atattgcttt tgaggtcttc tctgcgtttg gtacagtagg tcttacgatg ggattgacgc
    77221 cagacttgac tgcaataggg aaattgatca ttatagcgct tatgtacatt ggacgagttg
    77281 gtgtattgac tgtggtcttc tctctgatga caaaagcaca aagaacacaa tcaaaataca
    77341 aatatccaga agaaagtgtc atgattggat aatttcatct tctgacagaa acctagtgat
    77401 ttagtaaaat aagaaaataa aataattttt cttgcttctt ggatacttta agtgcaaaat
    77461 gttcgtttat tttttgaggc actatccgtt gttgaacctc gggtagtgcc tctttcttat
    77521 tgaaaggaat caataagatt tgattccttt atttatcaat aggttataat tcatattttt
    77581 ttattttttc ttttacgata cttagtccag aagctaaaat ttcaaggtta ttagaggata
    77641 gggaaattcg aacgaatgca tctggttgcg cacgtgtagt aaagcgtctg gaatgataaa
    77701 gtcggatacc gttagcaaga aagtcattct caattatctt aggatcaatc tcaggatcaa
    77761 ctggaagaat tcgatagtaa gggacacgat tcgttggttt ttctactttg aaaagagaat
    77821 caaaaagctg attggctctt ttcgtaagac ttaatttagt ttctaagatc ctatttgctt
    77881 catttgaatg gaggatttga gtgatgactt ccacatctaa tccagaagtt ttcacattta
    77941 tattaaaaat tgcttgttct atcttgtttt ggacatgtac tggaactaca agataagcaa
    78001 ctcgcaatcc agaacaaata aattttgtca ttccagctaa gtagattgtt tggttaggta
    78061 ataatttttg gaaaggagga atgatcgtat gttgatagta agttgttaaa aatgaatgga
    78121 tatcatcttc aataacccat agaccttctt tttcaatcac ttcggctaat tgctctcgtc
    78181 ttttgtgaga gatttgaaac cctataggat tattacaaga aggcataaga aagacaccat
    78241 gaatcttctt ttttctacat tcctgaatca atatatcagg tcgcattcct tgctcgtcaa
    78301 aatcaattgg aacgatctct aaatgatata actgagccaa ttcaatgaaa ttagcgtatg
    78361 tatatcggtc tgttgctatt ctatcacctg gagagaaaag tgcagaaagt gtgatagcca
    78421 atccattttg aacaccggaa acaatagata gagattctaa ggacggaatg actccttgag
    78481 tttttaacca atttgctgca gtagtcaatt gaaaatttgt gcctttggga tcttggtaat
    78541 taagcaaacc aacaagattt gggttattac tagttgattg aataaacggg acaacgaatt
    78601 tattacattc ttcaaaagaa ctaaccagac caaaatcaat gatatgttcg gttacttcat
    78661 tggtagagat ggtgatggac tcaaagacat tgggagaaat aaatgtgcca cttccaatat
    78721 tcgtatacag caaacctttc tcaattccat atttataagc cttgccaacg gtagtaaaat
    78781 ttaaatctaa ataatcagct agctctcttt gggagggtaa ctgagtgttt ttctgtaatt
    78841 tattctttaa aatatcttgt tctaattgtt gaatcaacga tcgataataa ggacgcttca
    78901 atttttgttt gtctggtcgc caagttaacg ggtaattgtc ataagaatta ataggcattt
    78961 tctacactcc ttaaaattgt ataccataca attttaccat tgattgtatt gattttagaa
    79021 gttaatcttt tgtgaggagg gaattgtcta tgaaaattat taattttgag gaagtagtag
    79081 cttcttttag ttttgaagaa gcgattcaag taatgaaaaa atgttttttt gattatgaaa
    79141 gtggtaaaat cagccaaaat cctcgattgg tggaaatttt acctgacgga aaagacaaaa
    79201 atatgtttgc gatgatgcct gcttatttgg gggagaacag atattttgga acaaaagtca
    79261 ttaccgcttt tccggataat catcagtatc atttaccttc tcatttagga gagattttct
    79321 tgtttgatgc tcaaaacgga ctacccaaag cattgataaa cgcaaatgca gtcacctgga
    79381 ttcgaacagc tgctgtatct gcgctggcaa cagattactt agcaaatccg catgcagaaa
    79441 cacttgcttt aattggagct ggtcaacaag cattgtcgca tttgactgcg atttctacca
    79501 ttcgtcccat cactacagtg tttgtttacg atattttaga agaaagacga aatactttta
    79561 tcgctaaagc taaaaaacag tatcctaaaa taacgtttat aaatgcaata tcagtagaag
    79621 atgcagtacg tccagcggaa atcatttgta cgttgacctc tagtaaagag gcatttcttc
    79681 aaaaagagtg ggtaagggaa gacgcacata tcaatgctgt gggcacattt actcctgata
    79741 caagagagat aagtacatcg ttgatggaaa cttctcaaat ctatgtagat gattactcag
    79801 ctaccttaac agaaagcggg gacctgctta tagccatggc agaaggagat ttagaggaat
    79861 cttgtattgt tggtacatta ggcgaattag tttctgagaa aaaaacattt tataaaggag
    79921 aatcgaggcc gacgattttc gacgcagttg gtctagctat tgaagatctt tgttgtgcag
    79981 aatatattta taacaaatta gagaaagggg ctttaaaatg aacttagatt attacgtagt
    80041 tgatgcattt gcagatgagg tgttcaaagg aaatccagca gcggtttatg tgctagaaga
    80101 atggctgcca gaaggtacga tgcaaaaaat tgccattgaa aacaatttat ctgaaacagc
    80161 atttacagtg aagaaaaacc aagaatttga gcttagatgg tttacgccag atcgagaaat
    80221 cgatctttgt ggtcacgcga cattagcaac agcatttgtt ttatttaact attacaaaat
    80281 acctgatgaa acgattaaat tttctactca aagcggtaat ctatttgtga caagaattaa
    80341 agattattat tacatggatt ttcctagtat tatgccgaaa aaagtgccga tattgactga
    80401 atatgaagaa gcaattgggg ctaagattaa agaagcctac ttagcacgtg atttattttt
    80461 cgtattagaa gatgaaaaaa cggtggctaa attgcagcca gattttacag ctatcaaaaa
    80521 ttttgaatta ggaatagagt catcgtgaca gcagaaagtg tgcaaaaaga ctttgtttct
    80581 agaaccttct ttccaaaatt aacaatcaat gaagatccag tatgtggatc agcacattct
    80641 aatcttattc cttattgggc agaaagaatg aataaaacaa aattgtcagc ttatcaaatg
    80701 tcatcaaggg gcggggatct agaatgtgaa ttaaaagaag atcgtgtgat aataggagga
    80761 aaagcagttt tgttttctaa aggtacctcg tttatttgat ttctttcaaa tgaattaaaa
    80821 ataaattggt ggagagtggc agccttatag ctacaatggt tgttaaaaaa agacgcaaac
    80881 tttttcaatt taatgaaaag tttgcgtctt tttttaatta ttggtgtttg ttttttattc
    80941 aatcaagagt aaaatgcccc atactaacta tcctcggatg acttcgattt tataaccatc
    81001 agggtcaatg acaaagtagt aagaaggcgt agtgccaggt aatcctttta agtcagtaat
    81061 ctcaagacct gcagctttat gttgctcgtg taatttttct aaatcatcag ctgcaatagc
    81121 gatatgacca tagccgtctc ctagatcata cgcaccatga tcatagttgt aagtcaactc
    81181 taattcatag tcatctccag gaagtgtcaa ataaacaagt gtaaatttgt tttctggaaa
    81241 atcacggcgg cggctttctt caaaaccaaa tgccttttga taaaattcga ttgatgcttc
    81301 aagatctttc acccgaacac atgtgtgagc cattttcata aattcatctc tccttttcct
    81361 tttactcaat cataacaaaa agaagtaaga aaatagttga tttgtgcttg ttcatgagaa
    81421 atttctcatg taaaatggat agaaaataat actgttaagg tggaaacaat tcatggataa
    81481 accaattttt ggtgaaaaaa agcaatctgc taattatcaa acccgttatg cagcatatat
    81541 tgtcatagaa agagacaagc ggattgcggt gatcgaggct ccaaatggtg cttttttcct
    81601 tcctggtggg gaaatcgaag gagaagagac gaaagaagaa gcgattgtcc gtgagctgat
    81661 agaagaaatg ggaattgtgg cagaaatttc ttcttatctg ggagaagctg atgagtattt
    81721 ttactcgaat tatcgtgcaa cttattatta taatccagga tatttctttg ttgctgattc
    81781 ttggaagcgt ataggagaac caactgaaaa gaccaataaa atttggtggg tgagccctca
    81841 agaagcgctt gtgaaattga aacgtggtag ccaccgatgg gcagtcgaga gatggatcga
    81901 aaaaaataaa aactgaaaga aagcgagtag atcagctttc tctcagtttt tttatttatt
    81961 acagtacata ttttttgatt gcttcagcta caccgtgctc gtcgtttgat gaagtgatga
    82021 catttgctgc ttctttgaca agagaaacgg catttcccat tgctactcct agaccagcat
    82081 attcaatcat ggataagtcg ttctcgttat ctccgatagc catgatttca tcttgatcaa
    82141 taccaaggtg ctgtgcgaga ttcgcaactg ccgcaccttt acttgcttct ttatttagta
    82201 cttcgaagta atagggcgca cttttgaccg ttgtgtattt atcacggaaa gtttgcggta
    82261 aacgcgcaat tgctgcatct aaaatttctg gttcgtcgat catcatcatt ttgacgatgt
    82321 tcatgtctgg tgtcatttct tcaggtgttc gatattttag cggcatcttg actaaacttg
    82381 cttcgtggat cgtataagcg ctgatatctc gattaggcgt gtagatcgct ttgtcatcga
    82441 tcgaatggag atgactgccg acacggcgtg ccatcacttc gatctctagg aaatcttcat
    82501 gagtcagtcc gtgacgggcg atgattttac ctgatttcgt ttgttgtacg agtgccccgt
    82561 tataagtaat aacgtaatca ttatcttgaa aaaggttcaa ctcgtttaac tgttcctgga
    82621 cacctggtaa gggacggcca gtgcataaaa cgatcgaaac accttttgca acagcagcgg
    82681 caatcgcttc ttttacttct tttgttactt ctcttttctc atttaataaa gtaccatcga
    82741 tgtcgatagc gactagtttg atagacataa tttcctccaa tatattttaa tttatttcaa
    82801 tcaatgcgcc attacggata tggctggcaa attcttgata agtttcgtca aataaatcat
    82861 aatgatcacg caaggaggga tcaaccattt cttttggaaa gaaaaatcgc tcatctcctt
    82921 gttcttgtcc cgctaatgca gcaacaagct gactaacctg tgataattct atcaaagttc
    82981 cgtcatttcg caaaatctcg atttgtgtgc gatgtctgcc ttgttctggg cgataaaaat
    83041 cataaggcag atcgtagcta gaattcacag cagtgtaata aacagggtta tagccaacct
    83101 tttctactaa caaagtgagt tcttggacta attttgaatc ccggttgcca gaaaaagtag
    83161 cagatttcag tggtttacga ttcaaaaaac gtttagctaa atcatttaaa ataggatcag
    83221 cagattcaga ccattgagta aagtaagtgc ccaagacccc atcatcaagt ttgaggtatt
    83281 cttctaaagt aaagcttccg tcaagaaatg gcagaagtaa ttgagaatgg agttcaaaac
    83341 tgctggcatc ttcttgatac aactcgtgtg cgcgatgaag cagatgctcc aaaatcactt
    83401 ccataccacg ggaaacagga tggaagtaca cttgcacata catttgatat cggctaacga
    83461 tataatcttc cactgcatgc atgccactca tggaaaaagc gatcccgcct tcataaggac
    83521 gaatcacacg taatattcgg gtaagatcaa atgttccata ttctgttcca gtgaaataag
    83581 catcccgaag caaatagtcc attcgatctg catcgatctg actagaaatc atttggacaa
    83641 cttgtgggtt ggggtaagtt ttttggatca cactagctac cttttcagga aaaccttctt
    83701 ctactcggtt aagaatctga tacacttctg tttctggaga agtgatgatc tctacagtga
    83761 tggcttcatg attcgtatgg aagatatgtt caaatgtatg agagtaagga ccatgaccga
    83821 catcatgcaa cagtgccgca cataaagtca ccagccgttc ctgatcatcc cagcctccgt
    83881 tgcctatttt ttcttttgaa aaatttcgag aaaagatatc gcagattcgt cttgaaatct
    83941 cataaacgcc taatgaatgg gtaaaacggc tatgttctgc tccgtgaaaa gtgaaagaag
    84001 aagtgcctaa ttgtttaatg cgtcgtaaac gttggacttc tttcgaattg atcaaatcta
    84061 agattacttt atgctggaca tggatatagt tatggactgg atcacgaaaa actttttcca
    84121 taggcagcat ttgatattta taaggggttg tcataatgta gctcctttat gttattacgt
    84181 tgttccattc tctggatttg gttgttccat tgctccagct ggatttcttt ttttagccag
    84241 tcggtagaat cctgtaaatc acttgcagaa tacagctttt caaaagcttt tgcaaatgct
    84301 tctttgactt cttttacaaa aaggggttgg tcaagcagtt cttcaagtgt tgccattgta
    84361 gcaggatcca ctgcaggata gccatttgta ccaaagtctt cttttaaagc agattgataa
    84421 aatcgcttca tgacttgccc gcgtttttcc tgattaccgt tgacacttaa gtacatcata
    84481 acagaaatcc catttttgat ccgacgctga gcgataccgg caaatttttt gccatggatg
    84541 cttaaatcat aagttccagg acaataagaa tgggtgattt cgaatgcttg tatcggtgcc
    84601 tttggaaaag cgtatttagt caataggagc atttgctcgt aagcgtcatc tatggttatt
    84661 ttttttgtgt cactttgagg gaaaatcaaa gaaatattta aaattccttc atctgatacg
    84721 atccctaatc cacctgaatt tctgatcact ggagcgtaac ctgcatcttt cagtgtttgg
    84781 atcccgtcac ttagaaaagg agttcgaaca tccttcatac ctaagatgac tgtgcagtca
    84841 tattgccaga aatgtaaaaa gatttgctgg tgttctttag aatattccgt taatatatct
    84901 gttaatgcaa aaggggaaaa gtcgtttttt tgataaatgt gctgatctag tcgaatcgca
    84961 gggttcattc aaccggctcc tttgtataaa ttcatatttt ctacaatatt atactctaaa
    85021 atcaaagagt tgttttggaa aaaaggtttt ctgtaaaaat ggacaagttg gttgacaaaa
    85081 caaaagaaac taggaacaat gtagctatga gaagtaaagg agaatgaata atggaattat
    85141 cacaaggaac accgatttca atcaaattgc gtacaaaagt aaaacagcaa ggggaagtgc
    85201 aagattttta ttttgatttg aaagggcaaa tggtgacaat tggcgatacg ctgtacatac
    85261 gttataaaga gattcaggag gagacgggcg atgagattcc tgtaacgatc aaattagttc
    85321 cagatggtca tgtacagctg atccgtgcag gagaaatgcg gatgcgtttg aaatttggct
    85381 ataaagaacg gttagaaaca tcctatcgaa caccatacgg tatgatccag attgctactt
    85441 ttacgaaaga actgcatgtt agtttgaaag accgtcccac agcagggaag gttcgaatcg
    85501 attatgatct gttcatggga ccggaaaaaa tcggcgaata ttatttgacc ttggatttta
    85561 cagcgtaaat ataaaagaaa agtttgattt tttgtgtctg attttgtatg ataaggagta
    85621 gactgtgaaa ggacgtgtcc tgattggaaa ttagtgtatt tgaaggtgca aacaaaagcg
    85681 aattatcaat gatcgaagta gcacacgcga tcttagaaca acgtggcgat gtcatggatt
    85741 tttctgattt agctaaccag atccaaaact atcttgagaa atcagacagt gaaattcgtg
    85801 attcactcgc acaattttat actgacttga atattgacgg cagctttatc tcattagggg
    85861 ataatcgttg gggcttgcgt tcatggtatg ctatcgattc gatcgatgaa gaagtaaacc
    85921 atggaatgga cgaagaggat gaagatactc cacgtcgccg taaacgcaag aaagtcaacg
    85981 cctttatcaa tgatgatgaa gacgcgatcg attacaatga cgatgaccca gaagatacag
    86041 atctgacaga agaagatgac gatgatctgt ttgatgacga tgatgatgaa gatgaagaaa
    86101 tcgctgctta taattctgac ttgcaagaaa tcggagcaga tgacccgaca gatgatgaag
    86161 aagacttgcc aggaaatatc gaagaagatt taagtatcat agacgaagac gatgatgatg
    86221 aagattatga agaggaagaa ttttctgact ctgaaaaaga ataaacatta ttttcttacg
    86281 agaggttgtg acagagacga tcagcctatc agaataagga ggtgtgacac gatttttgtc
    86341 acaccttctt ttttgtatat aaaaatccca agtaaataca taaaaaataa aaaaattgaa
    86401 acttttagcg caccttgtac gtcatattaa gtgaggcaga aaggagtgga gaatgatttt
    86461 tactggatat aagaaaaaac ggcagatcga aaaataccgt cacctgctga atggactcat
    86521 cgaaactgat tatcaaaaaa tgttccgtat cacgatgaat tacgtacatg ataaagaaga
    86581 ggccttagat gtgatgcaag atagttttca taaagccttg aactattttg aaaaagaaaa
    86641 agagatcgag cattttagtg catggtttta tcggatattg atccgcacgg cattagatag
    86701 ttggcgcaga caaaaaagga cgcctgtgga cttatttgaa attcaagata tcccccaaca
    86761 gttaccttta gaaacttccg ttgcagagct ccatatgatt ttagataaaa tagacagtcc
    86821 ggaaaaagag attctgatcc tctacttttt tgaaggattt cgtttgaaag aaattgcaac
    86881 tatcttggat atgaatgaaa acacagttaa aacgaaaatg taccgctcat tgaatgcttt
    86941 acgtcaaatc ctagaatgaa ggagagaaga gtgccatgta ttcccaaaaa gaaaatttaa
    87001 aaaaactaaa gaaaacttat aaagaacaag caattcccaa agggcttaaa gaggagatcc
    87061 gccagcgttt tattatcgaa gagcaatcat ttataaaagc aaggcggaga aagagacgtc
    87121 tccaagggtt cggagtatct ttggctatcg taatgattac aacaagtagc cttcttttta
    87181 atagtcaagt tcgaagcttt gcagaagatt tacccatctt aggatcagtc attgaattga
    87241 tcttaggcga acgctttact gatcgatctg aaaaaatcga tattcaggta ccgaagatca
    87301 atacacaaaa tgagaaagaa aataaaacaa ttcatggatt aaatcaaaaa tactttcgcg
    87361 aaggacaagc agattttgaa aaagctgaaa aagaatatgg aaattttgaa acggatcatt
    87421 accaagtttt gggagattat cagaaaatcg tagacgataa ccggtttctc gtgattgaaa
    87481 ggcagatcac ccaaacagca gcagatagcc atgttgaaaa aagatacgac acaatcgaca
    87541 agaaaaacag tgtccagctc tcacttccac ttttattcaa agatgacact tatctatctg
    87601 ttttgacaaa agaagtcaaa cggcagatgg ccgaacaagt caaggaagat ccatctaagt
    87661 actattggac tgagcaagat attcaagaag ggacgataga aaaaccaaca cttgttacgc
    87721 ctacacgaag tttttatttg aacaaagagc atcaattagt tttgactttt tctcaatacg
    87781 aaattgctcc tggttatatg ggtacaccag aatttgtcat tcctaagtcc gtgacaaaaa
    87841 cgattttggc atcggaagat tatttggatc attagacgag aagtagttgc gactagcagt
    87901 ttcaattttc aagtaagtac aagtaaataa taagaagaga aaaagagaaa gaagagatat
    87961 agtgaaaaga aattatttag tcatcagtat tattgcttta tccgtgcttt tgtttttcga
    88021 aattacttcg gtggcctcct tgatcaccga agtaaaagga caaacacact cttcggagca
    88081 ttcgtcacaa tctttcaaac aatcagaaca atcaaccatt aaaagccaat caactgaaac
    88141 agctaacgtc aaagaagcca ttcaagaatc agcggaaaag gtacaaagtc aatcatcaca
    88201 atcaacacaa gacagtacag aagcaatcca agacccgact gtcaaaagcg tcgcaatcag
    88261 ctttgatgat ggaccaggag cgaccacaac gccgcagctt ctgcgaatct taaaagaaaa
    88321 aaacgtgcat gtcacttttt tcgtcttagg agaaaatacg gcgcagcatc ctgaaatcgt
    88381 gaagcagaca gctgaagcag ggcacgagat tggcaatcac acatacgatc atcagaatct
    88441 ggccactctt tctgcccagt cgatgacgga ggaagtgacg aaagcagaca ctgagatcaa
    88501 aaaaagtcac tggcaaaacc cccgcttttg ttcgtccgcc ctatggttct gtcacgaatg
    88561 taggagcaac gatcatccag cgaccgatca tcgaatggtc tgttgattca gaagattgga
    88621 agacaaggaa tcctgatttg attttgcaga agatccaagc aacagtatac gatgggtcaa
    88681 ttattttatt ccatgatatc tatcctgaaa cgattcgtgc cgttcctcaa gtgatcgatt
    88741 atctgaaaga gcaaggctat cgcatcacga cagttagcga tttattaggg catccaacgg
    88801 ctgtcgagaa ctattatggc agaaacgatc atcggccagt tcagtaagtg agacaagtat
    88861 ctttaataaa taacacattt taataagtag ttgaacacat aactacctta cttgcaaagg
    88921 cttaacaata
//
LOCUS       DADVXM010000003        87928 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.003, whole genome shotgun sequence.
ACCESSION   DADVXM010000003 DADVXM010000000
VERSION     DADVXM010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 87928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.003"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            129..2570
                     /locus_tag="KB927_000206"
     CDS             129..2570
                     /locus_tag="KB927_000206"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBB6839156.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(2900..3604)
                     /locus_tag="KB927_000207"
     CDS             complement(2900..3604)
                     /locus_tag="KB927_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839157.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            3877..5304
                     /locus_tag="KB927_000208"
     CDS             3877..5304
                     /locus_tag="KB927_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa12 family transposase"
                     /protein_id="HBB6839158.1"
                     /translation="MMRKQSIEGRNQFAMLTIDDLVPKDHLVRKIDAAIQFDFIYPIV
                     ESTYSTHGRPSIDPVVLIKLVFIQYLFGIRSMRQTIKDVETNVAYRWFLGYSFEDPIP
                     HFSTFGKNYVRRFRETTLFEDIFSHILEQAVKAGFVTEDNLYIDSTHIKANANKHKFT
                     KEMTYGQAKAYQDELEDEINKERIVVGKRPFTWDTESELSLQKISHSDPESGYYVKGE
                     REKQFAYSAHTSCEDNGFILSTLITPGNVHDSQVAIDLVKQSKRAFPNIKRVVADAGY
                     KTPKFVHFLSHLKLYPILPYTVPHGVKGMFRKKDFVYDAYFDCYLCPNNQPLLFSTIT
                     RDGYRTYKSNPKFCRSCPLLKNCTLSTKHQKIVTRHVWADLMDELEHQRHTALNREIY
                     KKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLTFAAMNLKKLATWLWKAKKPM
                     AFYLKFLQRLTKRSWQLSHSFLSTV"
     gene            complement(5348..5593)
                     /locus_tag="KB927_000209"
     CDS             complement(5348..5593)
                     /locus_tag="KB927_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839159.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(5610..6461)
                     /locus_tag="KB927_000210"
     CDS             complement(5610..6461)
                     /locus_tag="KB927_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6839160.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            6627..7631
                     /locus_tag="KB927_000211"
     CDS             6627..7631
                     /locus_tag="KB927_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBB6839161.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(7872..8228)
                     /locus_tag="KB927_000212"
     CDS             complement(7872..8228)
                     /locus_tag="KB927_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6839162.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            8596..9783
                     /gene="tuf"
                     /locus_tag="KB927_000213"
     CDS             8596..9783
                     /gene="tuf"
                     /locus_tag="KB927_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBB6839163.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(9971..12562)
                     /gene="mprF"
                     /locus_tag="KB927_000214"
     CDS             complement(9971..12562)
                     /gene="mprF"
                     /locus_tag="KB927_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBB6839164.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(12588..13349)
                     /locus_tag="KB927_000215"
     CDS             complement(12588..13349)
                     /locus_tag="KB927_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6839165.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            13516..14148
                     /locus_tag="KB927_000216"
     CDS             13516..14148
                     /locus_tag="KB927_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBB6839166.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            14207..15067
                     /locus_tag="KB927_000217"
     CDS             14207..15067
                     /locus_tag="KB927_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBB6839167.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            15252..17567
                     /locus_tag="KB927_000218"
     CDS             15252..17567
                     /locus_tag="KB927_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6839168.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            17749..19590
                     /locus_tag="KB927_000219"
     CDS             17749..19590
                     /locus_tag="KB927_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBB6839169.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            19614..20723
                     /gene="rpoD"
                     /locus_tag="KB927_000220"
     CDS             19614..20723
                     /gene="rpoD"
                     /locus_tag="KB927_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBB6839170.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            20943..23042
                     /locus_tag="KB927_000221"
     CDS             20943..23042
                     /locus_tag="KB927_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBB6839171.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            23238..24101
                     /locus_tag="KB927_000222"
     CDS             23238..24101
                     /locus_tag="KB927_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6839172.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYGFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            24206..24679
                     /locus_tag="KB927_000223"
     CDS             24206..24679
                     /locus_tag="KB927_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6839173.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            24775..25662
                     /gene="xerD"
                     /locus_tag="KB927_000224"
     CDS             24775..25662
                     /gene="xerD"
                     /locus_tag="KB927_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBB6839174.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            25681..26052
                     /locus_tag="KB927_000225"
     CDS             25681..26052
                     /locus_tag="KB927_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBB6839175.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            26022..26819
                     /locus_tag="KB927_000226"
     CDS             26022..26819
                     /locus_tag="KB927_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBB6839176.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            26803..27372
                     /gene="scpB"
                     /locus_tag="KB927_000227"
     CDS             26803..27372
                     /gene="scpB"
                     /locus_tag="KB927_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBB6839177.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            27378..28094
                     /locus_tag="KB927_000228"
     CDS             27378..28094
                     /locus_tag="KB927_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBB6839178.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      28176..28301
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            28424..29035
                     /locus_tag="KB927_000229"
     CDS             28424..29035
                     /locus_tag="KB927_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6839179.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            29413..30936
                     /locus_tag="KB927_000230"
     CDS             29413..30936
                     /locus_tag="KB927_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBB6839180.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            31173..32513
                     /locus_tag="KB927_000231"
     CDS             31173..32513
                     /locus_tag="KB927_000231"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBB6839181.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            32666..33403
                     /locus_tag="KB927_000232"
     CDS             32666..33403
                     /locus_tag="KB927_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBB6839182.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(33568..33789)
                     /locus_tag="KB927_000233"
     CDS             complement(33568..33789)
                     /locus_tag="KB927_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBB6839183.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            33820..34851
                     /locus_tag="KB927_000234"
     CDS             33820..34851
                     /locus_tag="KB927_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6839184.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            34838..36241
                     /locus_tag="KB927_000235"
     CDS             34838..36241
                     /locus_tag="KB927_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBB6839185.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            36307..36942
                     /locus_tag="KB927_000236"
     CDS             36307..36942
                     /locus_tag="KB927_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6839186.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            36991..37671
                     /locus_tag="KB927_000237"
     CDS             36991..37671
                     /locus_tag="KB927_000237"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBB6839187.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            37806..39035
                     /gene="rpsA"
                     /locus_tag="KB927_000238"
     CDS             37806..39035
                     /gene="rpsA"
                     /locus_tag="KB927_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBB6839188.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            39217..40527
                     /gene="der"
                     /locus_tag="KB927_000239"
     CDS             39217..40527
                     /gene="der"
                     /locus_tag="KB927_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBB6839189.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            40770..41045
                     /locus_tag="KB927_000240"
     CDS             40770..41045
                     /locus_tag="KB927_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBB6839190.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            41280..42326
                     /locus_tag="KB927_000241"
     CDS             41280..42326
                     /locus_tag="KB927_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839191.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            42328..43587
                     /locus_tag="KB927_000242"
     CDS             42328..43587
                     /locus_tag="KB927_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBB6839192.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            43593..44174
                     /locus_tag="KB927_000243"
     CDS             43593..44174
                     /locus_tag="KB927_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBB6839193.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(44256..45131)
                     /locus_tag="KB927_000244"
     CDS             complement(44256..45131)
                     /locus_tag="KB927_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6839194.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            45279..45611
                     /locus_tag="KB927_000245"
     CDS             45279..45611
                     /locus_tag="KB927_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBB6839195.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            45723..46931
                     /locus_tag="KB927_000246"
     CDS             45723..46931
                     /locus_tag="KB927_000246"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBB6839196.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            47085..47540
                     /locus_tag="KB927_000247"
     CDS             47085..47540
                     /locus_tag="KB927_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839197.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            47902..48177
                     /locus_tag="KB927_000248"
     CDS             47902..48177
                     /locus_tag="KB927_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839198.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            48190..50268
                     /locus_tag="KB927_000249"
     CDS             48190..50268
                     /locus_tag="KB927_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBB6839199.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            50428..52314
                     /locus_tag="KB927_000250"
     CDS             50428..52314
                     /locus_tag="KB927_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6839200.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            52326..53273
                     /locus_tag="KB927_000251"
     CDS             52326..53273
                     /locus_tag="KB927_000251"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBB6839201.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            53293..53820
                     /locus_tag="KB927_000252"
     CDS             53293..53820
                     /locus_tag="KB927_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6839202.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(53883..54536)
                     /locus_tag="KB927_000253"
     CDS             complement(53883..54536)
                     /locus_tag="KB927_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBB6839203.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            54668..55510
                     /locus_tag="KB927_000254"
     CDS             54668..55510
                     /locus_tag="KB927_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6839204.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            55668..56564
                     /locus_tag="KB927_000255"
     CDS             55668..56564
                     /locus_tag="KB927_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6839205.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            56567..57280
                     /locus_tag="KB927_000256"
     CDS             56567..57280
                     /locus_tag="KB927_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBB6839206.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            57300..57818
                     /gene="msrA"
                     /locus_tag="KB927_000257"
     CDS             57300..57818
                     /gene="msrA"
                     /locus_tag="KB927_000257"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6839207.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            57815..58042
                     /locus_tag="KB927_000258"
     CDS             57815..58042
                     /locus_tag="KB927_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBB6839208.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            58194..58745
                     /gene="lepB"
                     /locus_tag="KB927_000259"
     CDS             58194..58745
                     /gene="lepB"
                     /locus_tag="KB927_000259"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6839209.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(58828..59328)
                     /locus_tag="KB927_000260"
     CDS             complement(58828..59328)
                     /locus_tag="KB927_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBB6839210.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(59607..60005)
                     /locus_tag="KB927_000261"
     CDS             complement(59607..60005)
                     /locus_tag="KB927_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6839211.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            60265..61125
                     /gene="ylqF"
                     /locus_tag="KB927_000262"
     CDS             60265..61125
                     /gene="ylqF"
                     /locus_tag="KB927_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBB6839212.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            61118..61885
                     /locus_tag="KB927_000263"
     CDS             61118..61885
                     /locus_tag="KB927_000263"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBB6839213.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            61941..62798
                     /gene="dprA"
                     /locus_tag="KB927_000264"
     CDS             61941..62798
                     /gene="dprA"
                     /locus_tag="KB927_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBB6839214.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            62920..64998
                     /gene="topA"
                     /locus_tag="KB927_000265"
     CDS             62920..64998
                     /gene="topA"
                     /locus_tag="KB927_000265"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBB6839215.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            64967..66343
                     /gene="trmFO"
                     /locus_tag="KB927_000266"
     CDS             64967..66343
                     /gene="trmFO"
                     /locus_tag="KB927_000266"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBB6839216.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            66541..67446
                     /gene="xerC"
                     /locus_tag="KB927_000267"
     CDS             66541..67446
                     /gene="xerC"
                     /locus_tag="KB927_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBB6839217.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            67483..68031
                     /gene="hslV"
                     /locus_tag="KB927_000268"
     CDS             67483..68031
                     /gene="hslV"
                     /locus_tag="KB927_000268"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBB6839218.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            68045..69445
                     /gene="hslU"
                     /locus_tag="KB927_000269"
     CDS             68045..69445
                     /gene="hslU"
                     /locus_tag="KB927_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBB6839219.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            69463..70254
                     /gene="codY"
                     /locus_tag="KB927_000270"
     CDS             69463..70254
                     /gene="codY"
                     /locus_tag="KB927_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBB6839220.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            70336..71211
                     /locus_tag="KB927_000271"
     CDS             70336..71211
                     /locus_tag="KB927_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBB6839221.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(71343..71981)
                     /gene="plsY"
                     /locus_tag="KB927_000272"
     CDS             complement(71343..71981)
                     /gene="plsY"
                     /locus_tag="KB927_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBB6839222.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            72108..72542
                     /locus_tag="KB927_000273"
     CDS             72108..72542
                     /locus_tag="KB927_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBB6839223.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            72708..74753
                     /gene="parE"
                     /locus_tag="KB927_000274"
     CDS             72708..74753
                     /gene="parE"
                     /locus_tag="KB927_000274"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBB6839224.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            74765..77215
                     /gene="parC"
                     /locus_tag="KB927_000275"
     CDS             74765..77215
                     /gene="parC"
                     /locus_tag="KB927_000275"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBB6839225.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            77492..79723
                     /gene="pflB"
                     /locus_tag="KB927_000276"
     CDS             77492..79723
                     /gene="pflB"
                     /locus_tag="KB927_000276"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBB6839226.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            79967..80728
                     /gene="pflA"
                     /locus_tag="KB927_000277"
     CDS             79967..80728
                     /gene="pflA"
                     /locus_tag="KB927_000277"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBB6839227.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            80813..81739
                     /locus_tag="KB927_000278"
     CDS             80813..81739
                     /locus_tag="KB927_000278"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBB6839228.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            81921..82814
                     /locus_tag="KB927_000279"
     CDS             81921..82814
                     /locus_tag="KB927_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBB6839229.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            82948..83073
                     /locus_tag="KB927_000280"
     CDS             82948..83073
                     /locus_tag="KB927_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6839230.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(83207..83839)
                     /locus_tag="KB927_000281"
     CDS             complement(83207..83839)
                     /locus_tag="KB927_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839231.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(83987..84529)
                     /locus_tag="KB927_000282"
     CDS             complement(83987..84529)
                     /locus_tag="KB927_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBB6839232.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            84664..85053
                     /locus_tag="KB927_000283"
     CDS             84664..85053
                     /locus_tag="KB927_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839233.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            85057..85821
                     /locus_tag="KB927_000284"
     CDS             85057..85821
                     /locus_tag="KB927_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6839234.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            85950..86897
                     /locus_tag="KB927_000285"
     CDS             85950..86897
                     /locus_tag="KB927_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6839235.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            87027..87767
                     /locus_tag="KB927_000286"
     CDS             87027..87767
                     /locus_tag="KB927_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839236.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
BASE COUNT        30105 a        15093 c        18442 g        24288 t
ORIGIN      
        1 attaaaagaa atataaaaaa gagaatattt aaggattgtt aaaatttaat cttagaaaaa
       61 aataactgga acaagagcta tttgttttta cagcaaagaa tggtatattt ttgtaggagg
      121 tggcttactt gaaagaagtc gttatgatag atgctgcaag aacgccgata ggaaagtatc
      181 gcggaagttt aagtccattt actgcagttg aattaggcac acttgtgact aaaggattat
      241 tagataaaac aaaactgaaa aaagataaaa tcgatcaagt aatatttgga aatgtcctgc
      301 aagctggtaa tggtcaaaat gttgccagac agattgcttt gaacagcggt ctccctgtag
      361 atgtcccagc aatgacgatc aatgaagttt gcggatctgg tatgaaagca gtgatcttag
      421 cacgccagct gatccaatta ggtgaagcag aacttgtgat agccggcgga acagagagta
      481 tgtctcaagc acctatgctg aaacagtatc agtcagaaac aaatgaatat ggtgaaccaa
      541 tttccagtat ggtcaacgac ggattgactg acgcattttc aaatgcacat atgggattaa
      601 ccgcagagaa tgttgcaaca caattttctg tgagcagaga agagcaggat cgctatgcct
      661 tgtcgtccca gttgaaagca gcacatgctg tcgaagccgg tgtattttct gaggagatca
      721 tcccagtcaa gatttctgat gaagacgtgt tatctgagga tgaagcagtt cgtggaaata
      781 gtacattgga aaaactgggc acgttacgta cagtattctc agaagaagga actgtaacag
      841 caggaaatgc ttccccgttg aatgacggtg cctctgtggt gatccttgca tccaaagaat
      901 acgcagaaaa taataatctg ccttatttag caaccatcaa agaagtagcg gaggtcggta
      961 ttgacccaag tatcatggga atcgctccaa tcaaagccat tcaaaaattg acagatagat
     1021 caggaatgaa tttatcaaca atcgatcttt ttgagatcaa tgaagcattt gcagcttctt
     1081 ctatcgtagt tagccaagaa ctgcagttag atgaagaaaa ggtcaatata tatggaggag
     1141 caatcgcatt aggccatcca attggtgcaa gcggtgcacg tatcttgact acattagctt
     1201 acggattgct tcgtgaacag aagagatacg gtattgcttc attatgtatt ggtggaggtt
     1261 taggcttggc agtcttgtta gaagcgaata tggagcaaac acataaggat gtgcaaaaaa
     1321 aaaagtttta tcagcttacg ccatctgaac ggcgcagtca attaatagaa aaaaatgtat
     1381 tgacacaaga aactgcgttg atttttcagg aacaaacact ttctgaagag ctctccgatc
     1441 acatgatcga aaaccaagtg agtgaagtgg aaatcccaat ggggatcgcg cagaattttc
     1501 aaatcaatgg caagaaaaaa tggattccga tggcaacaga ggaaccatct gtcattgcag
     1561 ctgcaagtaa tggtgcaaaa atctgtggaa atatctgcgc agaaacacct cagcggctga
     1621 tgcgagggca aatcgttcta tcaggaaaat cggagtatca agcagtgatc aatgcagtta
     1681 atcatcgaaa agaagagctg attctttgtg caaatgaaag ttatccttca atcgtgaaac
     1741 gcgggggcgg tgttcaagat atctctactc gggaattcat ggggagtttc catgcatact
     1801 tatctattga ttttttagtg gatgtaaaag atgcaatggg cgctaacatg atcaactcga
     1861 ttcttgagag tgtggcaaac aagttacggg agtggttccc tgaagaagag attctattca
     1921 gtattttaag taattttgct acagaatcat tggcttctgc ctgttgtgaa atcccattcg
     1981 aacgcttagg gagaaacaaa gaaatcggtg aacaaattgc caaaaaaatc caacaggcag
     2041 gggaatatgc gaagcttgac ccttaccgtg cagcaacgca caacaaaggg atcatgaatg
     2101 gtatagaagc tgtagtggca gctacaggaa atgatacacg tgcggttagc gcttcgatcc
     2161 acgcctacgc ggcaagaaat ggattatacc aaggattaac agactggcag atcaaagggg
     2221 ataaactagt tggaaaacta acggtgcctt tggctgttgc cacagtaggc ggagcttcca
     2281 atatcctgcc aaaagcaaaa gcatctttag ctatgttaga tattgattca gccaaggaac
     2341 tagcacaagt aattgctgca gtagggttag ctcaaaacct ggctgctttg cgtgcattag
     2401 ttacagaagg aatccaaaaa ggccacatgg gacttcaagc tcgttcatta gcgatctcaa
     2461 ttggggctat tggtgaggaa atcgagcaag ttgcgaaaaa attacgtgaa gcagaaaaga
     2521 tgaaccagca gacagctata caaatattgg aaaaaatccg ggaaaaataa aaaagcaata
     2581 tctttagaag aataaagcaa gatttacagt tattttattt actgcagatc ttgctttttt
     2641 ctctatcaga aaatatgttt attattagaa ttttttatag ttaaggttag gcatcttaag
     2701 aaatcaggca actccaagat atcttcaggt agaagagaag tcgcctaaca ttgtaggatc
     2761 ataggtgatt tgttggacag gtcaagctga tatttgagcc tgatgttaga aggaatttct
     2821 ttttacttgc tgtagaaatt attatatgac taaaaaggct gggattttaa atcccagcct
     2881 tttatgacaa atagaatttt tatcgatcag taatcgctgt cgctgcaaat tgttcgatca
     2941 aaggaatcaa agtcaatttg actttgtatt tccgttcgag tgctttttcg ataacgaact
     3001 cattttcagt agtcatagaa atagttgcta atttacgagg ttcatcagca tttttttcat
     3061 taataactac ttcatgttca ttttgttctg tgtaaaattt aggatactca gcaacggctt
     3121 ttgaaaaatc agcaaaactt aaagcggcat tcgtatcagt tgagcgtgta ttttcagttg
     3181 tgtccgcttt tggtttttcc gttttttctt ctggcacact gactgtttct tctgtaactg
     3241 gtgtcgcaac agcttgcgca gttggttcat cgtttttcaa tcgttgatca ttccagtaag
     3301 acacgatttc aataagaaga ttgtcacgga atcgttcgaa aatcccgttt tctcctgaac
     3361 gaattctctt taatacagta ttgaagttgt catcgattgg cacgttgatc cgtgtatctt
     3421 catttgtttt cccagctaat ccgatcgtta agatttgacg gtttttggga tcaagcatga
     3481 cttgtaacgg caaaccataa cgtcgcaagc tctcttcttc tagagaacgg aataattgtc
     3541 ctcttacacc atccaatgaa ggacggaatt gatttaataa tttttgtttc tgttttttct
     3601 tcatatgttc tctccttcgc tcataccctt tcgattataa gaaaaaaaca gccaaatgaa
     3661 aaggagtaat gcaaaaaaac ttgcgtatac gcaaattaca acagaaaaat ttgcgtattt
     3721 tcccgttttt tgaaagaaaa ataaaaaatg gaacggatta tgtatatata cataatccgt
     3781 tccattcaga ctgtagacaa actcctaaat tgggagtgtt gtttgcagtt tttttgtttt
     3841 atactcattg tataaactat tctgggagtg attctaatga tgagaaaaca atcgattgaa
     3901 ggtagaaatc aatttgctat gttaacaatt gatgatcttg tacctaaaga tcacttagtt
     3961 cgaaagattg atgctgcgat tcagtttgat ttcatttatc ccattgtaga atctacgtat
     4021 tcgacccatg gtcgtcccag tattgatcca gtggtcttaa ttaaattagt atttatccaa
     4081 tatttatttg gtatccgttc gatgagacag actattaaag acgttgaaac aaatgttgct
     4141 tatcgttggt ttttaggtta ttcattcgag gatcctatcc cgcatttctc tacttttggt
     4201 aaaaactatg ttcgaagatt cagagaaaca actttatttg aagacatttt ctctcatatt
     4261 ctagaacaag ctgtaaaagc tggcttcgtt acggaagaca acctttatat tgattctact
     4321 catattaagg caaatgccaa taaacataag ttcacaaaag aaatgaccta cggtcaagct
     4381 aaagcttatc aagatgaatt agaagatgaa ataaataaag aacgtattgt tgtaggaaaa
     4441 cgtcctttta catgggacac agaaagtgag ttgagtcttc aaaaaataag tcattcagat
     4501 ccagaaagtg gttactatgt taaaggtgaa cgagaaaaac aatttgctta ttccgcgcat
     4561 acttcctgtg aagataatgg ttttatctta tctacattaa tcacaccagg aaatgtacat
     4621 gacagccaag tcgcaatcga tctggtcaaa cagtcgaaaa gagcttttcc aaatataaag
     4681 cgtgttgtcg ctgatgcagg atataagacg cctaaatttg ttcattttct gtcacacttg
     4741 aaactctacc cgattcttcc atatactgta cctcatggag taaaaggaat gtttcgtaaa
     4801 aaagactttg tttatgatgc ctattttgac tgctatttat gtcccaataa tcaaccgttg
     4861 ttattttcaa ctatcactcg tgatggttat cgaacctata aatcaaatcc aaaattctgt
     4921 aggagttgtc cattacttaa aaactgtact ttgagtacaa aacatcaaaa aatagtaact
     4981 cgacatgttt gggcggatct tatggatgaa cttgaacacc aacgccatac ggcgttgaat
     5041 agagaaattt ataaaaagag aaaacaaacc attgaacgaa tatttgcaga tgcaaaagaa
     5101 aagcatggta tgcgttggac gaaatatcga ggtctcgaaa aagtcgccac gcacacgatg
     5161 cttacgtttg ctgccatgaa tttaaaaaaa ctagccacat ggctatggaa agcaaaaaag
     5221 cctatggctt tttatttaaa atttctacaa agactaacaa aaaggagttg gcaattaagc
     5281 cactcctttt tgtctacagt ctgaatggaa cggattatgt atatatacat aatccgttcc
     5341 attctttcta ttttttcggt atcaaggcaa aaacaggtag ttcaggtgaa taaatgactt
     5401 catgttcgtg ccagggtttg accattagcg aatgatcgaa ccgttttttc agttcttcga
     5461 tgatttgatc atgtgtccag tttcttgcag gaaaatgttg gattttctct gcatcgatca
     5521 aaaagacaaa atcggaatga aaagtctggg taacttcttc cgagagagaa ttcaagcgtt
     5581 cgattggatc cataaaatca cctttcgact taaaattggg tagtatctgg gtcttttgct
     5641 ttgccgacta caccatctaa ctgatcgatt tgtttcattt cttcttctgt taattcaaaa
     5701 tcaaataatt cagtattttc tttgattctg cttggtgtca ctgacttagg aagaggaagg
     5761 aattcgtgtt gcagcgacca acgcaaagca acttgtgcaa tcgtcttgtc atgtgcttca
     5821 gcgatttgtt tcatttcagg cacatcgaag attttaccag tgcctaatgg actatatgct
     5881 tcgaggatca tatcatgttt ttttgcatac tcaactacag ttgtctgtaa ttcgcctggt
     5941 gcaaggaaaa cttgattgac catcggcata atttttgctg tttttgctag tgtatctaga
     6001 tggtggggta agaaattgct cacaccgatt gctttgattt tacctgcttc atacagttct
     6061 tcaaatgctc gccatgtatc tgcatttgct tgttcccaat tatcacgaaa agcaacaggg
     6121 tttggccagt ggatcaaaaa cagatctaaa taatctgttt ggagcttctt caatgattct
     6181 tcaaaagaag acatcacaag ttcatagctg tggtttgcat tccataattt tgttgtcaag
     6241 aatatctctt ctctaggaat tccactttcc ttaatcgctt ggccgacgct ttcttcattc
     6301 ttgtatcctt gggcagtatc gatatggcga taacctgcag ccagcgcttc tttaacagag
     6361 gaaacagcga catccccatc aggtgtttgc catgtgccga atcctactac cgggatttcg
     6421 taaccatttg atagacgata agtgcttgtt aatgaattca tactttcagc tcctttttta
     6481 ttcgttcaac tataagtgta gcgcattttt cgaaaaaaag aatccatttt gtttctactc
     6541 ttgaaatttt tgtttaaaag aaaatgattt tgattctggt atttttgatt ttttttccgt
     6601 aaactaagac agaagggaat gagaaaatgg atatctattt aaaaaaagca attctgcata
     6661 ttattgacag agaaactggt tctccagtct tttcacaaaa agagctggat ctgacaaaag
     6721 aatatattcg tgattttctt caaaagaaga tccaaaaaat ctcttctgct caaacaaaaa
     6781 ctggacaact agcagaagaa agcatgatcg ttgaatcact taaaatcgct caagaaaatt
     6841 ttgtggaagc aagtgaagca atcgttcagc ggtggttcga tatctaccaa gaaagtgaag
     6901 aagcacctag tgcagatgta tttgttgtct tgtatgaatt agatacagtg atgtacttat
     6961 ctttattgaa agtcaattat cgtgaggctt acactcactt tgttgaagca gacgaagcag
     7021 ggatcgacaa ccgcttgatt ttgaatcgag caattctagg ggcgaaaaca caaaaagcag
     7081 atgaagcatt cgctgtgaat ttgactgatt ggacctacga attaattgaa aaaaaatatg
     7141 agttttctgg caaaaaagag ctttattttt ctggaagagt gatcgaaagt gttcctgcac
     7201 cttctttaga agaaaatgta aaagtgatcc aaaaagtagc caagcatctt ggaaaaaaat
     7261 ttgagacaga agaatttgat atcatggctg atttgaaaga agctgtctat gatacgatag
     7321 aagaaaaagg tcggttggat catgagatga ttgcggaaaa agtcttcaag gaaaacatca
     7381 cggcaaaaat ggcttttaaa gaagaagtac aagagcaagg atttgtccca gaagcacctc
     7441 ctgtaaaaga agtacaagaa atttctgaga aaaaatttgg aaaacaaaaa ttcaagctat
     7501 caaacgggat cgaactgatc gtaccagtag atgtatatcg caacccagat ttgattgaat
     7561 ttgtgaataa tccggatggt acgatatccg tgatgatcaa aaatgtggat gaagtattga
     7621 atcgtttata aaaatgacta gaatattagg tgttcaagta ccagtgatca gttaaatgaa
     7681 ttgtgtcaag agaaggatcg gaaaagacga atataacaaa aaaagagcgt gagacaaaag
     7741 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcggaagca gaagcaactc
     7801 cttcttattt cttggagtta aacgcttctg tcccagcctc tttttatcta ataaaatttt
     7861 aagaccattt actaattatc gattttttct gccgcatttt taggcacttc agaagccttt
     7921 atttcttccc agcttaatac acctttacga ggattgactt tgagtttaag atacgcattc
     7981 atctttaatg gatgttctct ttcttcgcga agcgtcacct gttttttttc accatcttta
     8041 ttataagccg cttgcttgta ggtataagtc gtgaatttct ctccgttatc tgcttgggta
     8101 gctgacattt cgccattcgt cgtgattttt gtataataag cttcgccgcc gtaaaaataa
     8161 tgataagctg caaaacttcc gccgagaaat atgcctaaaa cgacaagtac gccaattaat
     8221 tttttcatgt acttcacctc tttccttatt attaacgaaa tagaagattt cgtctattga
     8281 aagttgttgg caacagctga attttaaact tttcctcatt ttgttcttat tgcttcaaaa
     8341 gaaagttaag gactatcttg aagtttttct caaaaaacac atttttttat ttataaaagg
     8401 tacttttttc gcgtataaga cagacgagtg ctcttagttg actttgacca atattgacgt
     8461 ataataagct tagttcgaat cttacaaaaa gtaagtcgga cgtattcttt ttgatttagt
     8521 caaaaaaaga ctataataaa aaggtgagag ctgaaatttt tcagtgatct atattattta
     8581 ggaggtttgt aaattatggc aaaagaacat tatgacagaa gtaaaccaca cgttaacatt
     8641 ggtacgattg gacacgttga ccatgggaaa actactttaa ctgctgcgat cactacagta
     8701 ttaggcaaaa aaggcctagc aaatcctcaa gactatgcta gtattgatgc agctccagaa
     8761 gaacgtgaac gtgggattac gatcaatacc gcacacgtag aatatgaaac agaaaaacgc
     8821 cactacgcgc atattgatgc accaggacac gcggactatg tgaaaaacat gattacaggg
     8881 gcagcacaaa tggatggtgc aatcttagtt gtttctgcaa ctgacggtcc gatgcctcaa
     8941 acacgtgaac acattttatt gtcacgccaa gttggtgtaa aatacctgat tgttttcttg
     9001 aacaaagttg atttagtcga tgatgaagaa ttgatcgatt tggtagaaat ggaagttcgc
     9061 gagttattga gcgaatatgg tttcccaggc gatgacactc ctgtgatcaa aggttccgca
     9121 ttaaaagcat tgcaaggcga tccagatgct gaagctgcta ttatggaatt gatggataca
     9181 gtagatgaat atatcccaac accagaacgt gatacagata aaccattact attgccagtg
     9241 gaagacgtct tctcaattac aggtcgagga actgttgcct caggtcgtat tgatcgtggt
     9301 gctgttcgtg tcggtgatga ggtagagatc gtagggatca aacctgaaac acaaaaagca
     9361 gttgtaacag gtgtagaaat gttccgtaaa acgttagatt acggggaagc tggggataac
     9421 gtaggcgtgt tgttacgggg gatccaacgt gacgatatcg aacgtggaca agtacttgct
     9481 aaaccaggtt ccattactcc acatacaaaa ttcaaagcag aagtgtacgt gttgacaaaa
     9541 gaagaaggtg gacgtcatac tccattcttc aacaactatc gtccacagtt ctacttccgc
     9601 acaactgatg ttacaggaac aatcacattg ccagaagata cagaaatggt catgcctggt
     9661 gacaacgtga cgattgatgt tgacttgatc catccaatcg ctgttgaaaa cggaacgaca
     9721 ttctcaattc gtgaaggcgg acggacagta ggttcaggta tcgttacaga gatcgaagca
     9781 taagaaacgc gactcgaata ttttggtaat gaaaaatgtt taaaataaaa gagcggtcca
     9841 aacaggattt ctgtttggac cgctctttgt tcttcaattg tataagaaga gattgtagaa
     9901 gcatgaactt tcgttttact tcagtctctt ttattcatca tgagagtgtt catctatcgg
     9961 tatgcagttt ttaatacttt cttcgtatcc attttttcaa accacttatt ctaccttgtg
    10021 tctgctcaac tggcgcatta tcaataatca gcaaagcaat cataacatat gcaatccaac
    10081 tatctctaga atatagagta taacgtgaga cccagtttgt agcgtacttg cttttatatt
    10141 ctcttaatcc atggaaagaa taaaaatgag aaccaaactc gtaaaccaag tatgcaatcc
    10201 tttcctgtaa aaaactcttt ctggaagttc cgacatttga aagaggggcc atccctaaat
    10261 tgaaccattg gatatgttct tctttcatat aggcaaacaa atgcaagaac aagaaatcca
    10321 tactgccaga aggtgctttt ttagaatcat atcgcatcag atcaatcgtt cctactttat
    10381 tgttcgtgta agtaggcatg atcgttgcaa aagcgacaat ttcttcttgg gtatttttga
    10441 caactgcaat aggcgctctt tgtagataat cttcagagaa aaagcctaaa gaaaaccctt
    10501 tttcctttcg tgaacccaac caattatcag agatattttt gaaagtactc atttgctcag
    10561 tagaaaatgg tggttgtaag acatcaaatg taaatccttc tcgttcgatc cgattcaaga
    10621 cagcacgagt gcccttcatt tttttccctg aagttgtaaa actattcagg tctacataag
    10681 cttcttcccc catcttaatg aaatcgtagc cgaattcatg caaaatcata acaatctctt
    10741 cgcttgtttc gtagaaaact ggtaaatagc atagtcgatc tgtttcttcg ataaaagctt
    10801 cgattgcttc tggaaaatct tctttcttac cagaaggatc acccattaca atacatttat
    10861 tattgaagca agcgaattgg agaagaacag ttggttcacc gtctttttca taggcaaaca
    10921 tccgcttatc ttttaagaag atcaattgac tatcggagtt tcctccataa gttgtaagga
    10981 tcttcagggc cttttcttca ttaaaggctt cgccaatctg tttcttttct ccttgaagga
    11041 aatgaacaaa tagaacgatc atgaaactaa cagcgatgat ggccaacaat cccgaaaacc
    11101 aaatcttttc agaaggaaat aagaaaaagg aaataaaatg gtgacgccga tgagggaaat
    11161 ccggcagatt gtatacccca ataacgatgt aaagcaagga cagtgcacca ataatgattc
    11221 catcgatcgt acgccactcc catgaataga tcaattgttc ccgaaataat tcgtttttag
    11281 aagcaagaat gatcagaagc agaatagaca agaaaaccac cggtgtgaaa ctaaaatcac
    11341 ttaataaaac ataaagtaaa gctagaacaa tcaagaagat tgtaggcaaa tatgctcgtt
    11401 tcacacgtgc tgcgatccct ctgcccataa tgattaaaag aaatcccaat agtatactag
    11461 gaaattggat aataaaatga aatttcaatg ggttcaaact atgaagccag cgaaactctg
    11521 taaaagcttg cgggatagtg gcagaaagta ctagcatgat tccagaaaag tataataaga
    11581 caaccacgat tttatgcgca atttctgttg ctaattgttt agggatacca gaataacgct
    11641 gatcaaaagt ggaaccgata tttttgaaga aaaagacgat tccaatcaaa aacggaatga
    11701 tgtagtagaa caggcgatag agcaagatcc acacaacgac tatttctctt ggcacaccaa
    11761 tagcggacaa cccgataatc atcattacat cgaaactccc aatttctcct ggaatcatag
    11821 acacgattcc tatcactgaa gcagcaatga ataatggaat tgtttgccac agatcaatcc
    11881 ggatttccat taaataacca acagaaagga aactaaacag gacaccggtc cattccaaca
    11941 atgaaactag caatagctgt ccttgagttt taagtgaggt accaccaagg aatcctttct
    12001 ttttgaaagt agtaaataaa aagacgacag gaaaatatag accgccgccg atcaaccata
    12061 tccaatattg cttcaaaaaa ggagcaactg gcgtgaagac tacaagtaaa aaagaaagca
    12121 gactgtaaat agaaagtcca gccatcaaaa acaagaaaac tttcgataat gcttggatca
    12181 cgtttctgct ctctttcttt tgtccatata gttcagagcg aagccccaca ctaacaaacc
    12241 cgccgaaacc ggcaatattg ttgatcgtat tgatcagcca gcttgtctca aacaggtaac
    12301 gaggattctg cttttgttca agcatccgat tcaaaataat atcataacca accataggta
    12361 acacagagat aagaccaatc aatagcatta gtccgctttt ccatacaggt atagtggcaa
    12421 acgtttctcc taattgctgg atagatagag ttttaccgat ggacatcaat tcaccgacaa
    12481 taatgacaat gacagaaatc aaaaagattg ttttgaacag tcctaggtgg tttttcagcc
    12541 attgtatggt attttttaac aaataaatca ccttctattc ctaatagtta tgtttcagaa
    12601 agaaattgaa gaacttctcg attgaagcgt tcaggatctt ttctagctaa ttcatgtcct
    12661 tgttctttca caagcacaaa ggaagctttt ggtatagttt tagctatata caaagaatgt
    12721 tttagcttga ttacatcttt ttttcccacg atgatcaaag tgggggagtt gatttttttt
    12781 aaatcatttt ctgtaagccc gatgtcatgc agcaaaagtt tgataactaa aagatttttg
    12841 cgaagacttg ggcgaaataa agagagtaac catacccatg cataatgaat attactgatg
    12901 actctggcag aaaaacgaac gcctttaaca agcgtgtttc cagaatttaa aatcaatcga
    12961 tgaacttttt tagggaagct gctggcaaat accagtgcta gatttgctcc atcactaaat
    13021 ccaagaaaat ctgcctgatc gattttttcc agcaacatga tcgtattcag atcctcggcc
    13081 attaactgaa aattcaacat agatgcttcg tttgtcgaac gaccatgtcc tcggctatct
    13141 actagataca cggtatagta gcgttcgagt acagggacct gttctgaaaa aaagcggccg
    13201 ctgccgtcat tgccatgcag taaaaagaga gggaagcctt gaccgctctt ttcatagtaa
    13261 atttcgctcc catctggcat ttttgcatat ttcttttctt ttttcacata atcacctact
    13321 gtgtaaagta taacgattat atcagtcatt gggcaattgt ttttactgaa aaacaacgat
    13381 cattttcgta agatgtcaaa aaatacagga aaattcattt tttcttaagg cgtacacaga
    13441 aatcaaggaa gaaatagcca agaagataaa gaaatagtaa gataaaaaaa gatgtcaaaa
    13501 taactaggtg atgaaatgaa gcgaaaacga ttatctatta tccgtattct tttttacatg
    13561 atcattctga cggttattgg tgcggtgttg tttttaggag gaagaactta tcgttcggta
    13621 aaacgagtgg aaagctatca aatagaaata acaacagctg caaaaaatta tcatatggaa
    13681 aactacgaga atttgatcaa ggcgataata ttgaccgaat caaaaggaaa agggacagat
    13741 ctcatgcaga gctcggaaag tctgcatgga gaagctgaga tcattgataa tccagctgac
    13801 agtattgatc aaggtgtcaa atatttggcg gaaatgatag tagaagcaaa gaaacaagga
    13861 tgcgatttat ggacagctgt ccaagcatat aattttggga aagattatat tgcctatgta
    13921 aaaaatcatg gcggagaaaa cacagtagaa ttagcagaag cgtattctaa agatgtgctg
    13981 agcccacttt taggaaatga ggaagggaaa caataccgat attggcggat ccagtccttg
    14041 ctttacaatg gcggctatct ctatcataat ggaggtaaca tgttttatcc tgatattgtc
    14101 aaaatgaatg aaaaaataat agagacctat gaaaaagtct ttaagtaaaa tagcaggaaa
    14161 tgttcaatca tgaataaaat taaatgaaag aaggagtgcg caaatagtgg aaaaaaggca
    14221 aaaaatggaa aatcaagaag tggggtacac aaccaaagac tggatgttac ggtttgtgaa
    14281 gggaatgttt atcggttcag gatttatctt gccaggagtc agcggtggtg cattagcagc
    14341 tgtctttggc atgtatgagc ggctgatttc ttttttagcc caccttacaa aaaatttcaa
    14401 agaaaatgtt ttgttttttc tgcctgttgg tctaggcgga gtgacaggca tctttctact
    14461 ttctttttta gtcagttttt tattaggtgc gtatgaaaca acgatattat ggttttttgt
    14521 cggatgtatc gctggaactg ttcctgcgtt atggaaagaa gcagggaaaa aaggaagaga
    14581 tacttctgat gtgatcatca tggttgttac ttttgttctg gcttatttgt ttttattata
    14641 cggcgctcaa ttatttgacg ggcaagtcga tcagaatttt ggaacatggc tgattgccgg
    14701 cggattgatt ggtttgggta tgatcgtccc aggattgagc ccttctaatt ttttggtgta
    14761 tatgggattg tataaagcga tggctgacgg atttaaagaa gtacgacttg aagtgattgt
    14821 gccgatcgga attggtggga ttctttgtgt tcttggattg tcaaaaatca tggattacat
    14881 tttctcaaag gcatatagca agctattcca tttcatttta ggtgtagttt ttgcttcaac
    14941 gattatgatc attcctaccg attacgcggg attgggagtt gctggggtac tagcttgtcc
    15001 tgttcttttt atagccggta cagcactagg ttggtggatg agccgtttgg aggaacaata
    15061 taagtaaaga tagattgata ataaaaacag cacacgggtg attcaaacaa aaaggttggc
    15121 atcttttttg taaaatcatt cgtgtgtttt tctataaatt ttataaaaac aagttgtttt
    15181 taatcttgga acacgctaga cttaaacacg tgattatttt tgaaagttgg cggaaaatgg
    15241 agaaaaagaa aatgaatgga cttacacagc aagaggtagt tcagaaaatg gcttctggcc
    15301 agcaaaatga ctaccaggaa gatgcatcaa aaagtacaaa acaaatattc agcgataata
    15361 tattgacgtt attcaatttt ctgaactttg gtattgggat ttgtctgtta tttgtaggtg
    15421 cgtattccaa catggcgtat ttagcaatta ttgtcgtcaa tatcgttatt ggaatttatc
    15481 aagaaataca tgcaagaaat cttgtacgga aattatcgat tgtttcccaa tcagaagtac
    15541 tagtgatccg ggacggtaaa gaacaatcga tttctactaa agagctggta ttaggagatt
    15601 tggtaaaaat cggagcagga gaacagatac cagccgattt acaggttata tctggacggg
    15661 cagaagcaaa tgaagctctt ttgacaggcg aatctgattt gattgtcaaa gaaactggag
    15721 ctgaattgct ttctggaagc tttttgacaa gcggttctgt catggctgaa gttatccgag
    15781 taggtgcaga taattatgct gtccgcttga ctagcgaggc aaagactcac aaagctattc
    15841 gttctgaact tgtagattcg attcgcaaag tatccaaatt cactagtttc gtgattattc
    15901 ctttggggat catactattt ttggaagcac tgttcatccg cgatgcttct atcaaaattt
    15961 ctgttattgc atctgcagca gctttgttag gcatgcttcc aaagggtttg gtattgctaa
    16021 taagtattgc attaacgaca ggggtaacca aactggcaaa aaaacgaatc cttgttcaag
    16081 acatgtattc aattgaaacg ctggcccatg tcgatacatt atgcttggat aaaacaggga
    16141 ccattactga agggaaaatg agtatccagc gggtagaagc actacatccg ctgtacgaga
    16201 aagccatccc agaaattatg gggacgtatc tggcagaaag cagtgataac aacatcacta
    16261 tgcgggctat gagagattat tttgagcttt ctaatcggta tgatgtgaca aacaaagtcg
    16321 cattttcttc tgatcgcaaa tggggcgcga tggaatttcc agaactggga gtcgtgtacg
    16381 taggagcgcc tgaacgtttg gtggaagaag atcggcttcc ggacagtcta aaaacagccc
    16441 aagcgaatgg ctatcgcgta cttatgttgg ggatcgctcc aaatcagcaa ttgaacgaag
    16501 aaaaaccagc atttgttgag ccggttgctc tgtttgaaat cgatgatcca atccgaaaaa
    16561 acgctcaaga aacactagct tatcttcatg aggaaggtgt ggatctgaaa gtgatttctg
    16621 gagacaatcc ttttactgtc tccaatatcg ctagacgtgc aggattaccg aattatgatg
    16681 cgtatgtcga tctttctcaa attactgaag aaatggaagt gcgagaagct gctcatcgct
    16741 atacggtttt tggacgagtg agtccgcagc aaaagaaatt gctggtaaat gaattgaaag
    16801 aaagcggcag aacggttgca atgacaggcg acggtgtgaa tgatgttttg gcgttaagag
    16861 aagcagattg cagcattgct atggcagaag gtgatggagc aacacgtcag attgcgaatc
    16921 tggtattgtt ggactctgat tttactacat tgccagaagt cctgtttgaa ggacgccgag
    16981 tggtcaacaa tgtgacgaaa gtctcaggca tcttttttat caaaacgatt tattcattta
    17041 ttttatcgat tatatgtgcc gttacagcaa ttggatttcc gtttatccct atccaaatca
    17101 cgctgattga tttagcgatt gaagggtatc cttccttctt tttatctttt gaacaagata
    17161 aaagaaaaat cacttaccgt tatttgccta cagcacttat taatgcttta ccaaatgcct
    17221 tgcttgtagt agtgaatatc attgcggtgt atctacttgg aaaaacattc gcatggggaa
    17281 atgctgaaac tactactttg atgtattact tgctgattgg gatcagttgc atggcagttg
    17341 taaaagcttg ttatcccttc aacccattgc gcatcttcct agcagtaacg acgatcgtag
    17401 ggatatatgt agctgcaatg ctgttccatg gaattttgga agtaaactta gggttgggag
    17461 agagcgtagg atacttcttt gtattcatgc tcgtaaatat tgttcttcga gtattgtact
    17521 ggaaggctga tattcaaaat cagttactga aaagagtagc aaattgatgc ttaatgagat
    17581 agaaatgtgt tatacttgaa aaagcaatga aatatgatac aatcaaacat gtataattgt
    17641 gtcctttaaa atcgcactga tttcagttag tgcgattttt taccggttat tctcctgaaa
    17701 tatcttctgt taaacccaaa agatatcaat agagcagggg gtgaaaaaat ggctcaacgg
    17761 attcctcaag aggttatcga aacagtacgc agtcaaacga atatcgttga ggtgattgga
    17821 caatatgtcc agttgaaaaa gtctggtaaa aattacttgg ggctgtgtcc ttttcatgaa
    17881 gaacgtacac cgtctttttc tgttgcagaa gacaagcaga tttttcattg ctttggttgt
    17941 ggtaaaggcg gaaacgtgtt tacttttctt caagaactag aaggtctaag ttttccagaa
    18001 gcagtggtaa aagtggcaga cttcgaacag ataccgttag aagatcaatg gcgtcagcgt
    18061 actatagctg tccaaaatcc tgaatctgct acggggaaac tgattgctgc tcatgaaaaa
    18121 gcagcggaaa tctatcatca catgctattg catacaaaag ctggacagcc agctttagaa
    18181 tatttgcaaa gtcgtgggtt gtctttagaa ttaattgaag aattcaacat aggttttgca
    18241 cctaatgagc gttcttttct tcagcaagta ttcaagaatg aatcaatttc aaatgaattg
    18301 ttagaacgct ctggattgtt tgtcacgcat gatgatggcc gtatgtctga tcgtttttat
    18361 caaagagtga tgtttccact tcgtaattct caaggccaga cgatcggttt ttcaggacgc
    18421 tggcttgcac ctgaaaaagg gcaggaaaaa gatcagccca aatacttgaa tagtccagaa
    18481 acagaactgt tcaataaaag acaagtttta tttaatcttg ataaagcaag aagcgatatc
    18541 cggaaaaacg gagaaatttt gttgttcgaa gggtttatgg atgtgattgc tgcatggcag
    18601 gctggtatca aaactggatt agcttctatg gggacaagtc taacagctca acagatccaa
    18661 caaatggaaa agctgacgaa agaattggtc ttttgctatg acggagacaa cgcaggtttt
    18721 gaagcaacca atcgagggat tgaattgctt cggcaaaaca gtcgattagc actttctgtc
    18781 gtagtcgttc cagaaaagct tgatcctgat gaatatctcc gtaagtatgg agaagcatct
    18841 ttccaagaat tagtggctca tgggcgcgaa acagtcttta cttttaaatc acgttattta
    18901 aaacaaggga aaaatttaga taatgaaaaa gacaagatcg aatacctcga agaattacta
    18961 gttgaactta gccgagttgt ttcaccaatc gaacaagata tgtatctatc tcaactgtca
    19021 acagagtttc agatcggcag agagacgata caaaaacaac tgcgcgatct tcgaaggaca
    19081 aatcagcaaa atcgtcaaga acctcaggaa agtcaacaca ctcaggttac gagacaagaa
    19141 actgcacgga aaaagagacc tttgacgcaa gtagaaaagg cagagcagat tctattatat
    19201 cgtgcattta aagaagtttc tgtccgtaat attttaaaag aacgagaatt tcagtttatt
    19261 catgatgcat atgcagaagt ttatttttta ttcgatgcat atgtctcaca acattatgaa
    19321 ttcaaccttg cagagttttt agactttttg caagatgaaa atttaaggcg gttggtggtg
    19381 gaaatcgaat atttaccggt ggcagaagaa agttcgccac gagaaatcca agacttgcta
    19441 gatgtgatca gcaaatctgg cttagctgat gaaataacat taaaaaaaca aatgcagcaa
    19501 gaagccagac gaactggaaa caaacagctt gagcttgaat tgacgattga aatcatcaat
    19561 ttaacgaaac agttaaaaca agccaaatag ctactcaagg ggggccttct tttatggcaa
    19621 atggaacaga taaaaaaacg tatgaagcag cagtagcagc tttcatcaaa gaaaacaaac
    19681 ccaaacgaca agttgtatat gatgatttat ccaatcagct tgctacacca ttcactttga
    19741 atgcagatga aatggacaaa ttgatccaaa agattgaaga cgcaggtatc agtgtggtgg
    19801 atgaaaatgg tgatccatca attcacagct tgaagagtgc tgagaaaaaa gctgaacaag
    19861 caaaaacaga agatctttct gcgccaaccg gtgtaaaaat caatgacccg gttcgtatgt
    19921 atctgaaaga aattggccgt gtctcccttt taactgcgga agaagaagta gcgttagcat
    19981 tgaaaatcga agaaggcgac caagaagcga aacagcgtct ggcagaagca aaccttcgtt
    20041 tagtagtaag tatcgctaaa cgttatgtag gacgaggcat gcagttcctt gacttgatcc
    20101 aagaaggaaa catgggactg atgaaggcag ttgaaaaatt tgactaccgc aaaggattta
    20161 agttttcaac ctatgctaca tggtggattc gtcaagccat cactcgagca atcgctgacc
    20221 aagcacgtac gatccgtatt ccagttcata tggttgaaac aattaataaa ttgatacgta
    20281 tccaacgtca attgctgcaa gaccttggaa gagaacctac gccagaagaa atcggtgcgg
    20341 aaatggatct tccaacagaa aaagtccgag aaatcttgaa aatcgcgcaa gaacctgttt
    20401 cccttgaaac gccaatcggt gaagaagatg actctcactt aggtgatttc atagaagacc
    20461 aggaagcaac aagtccagca gaacacgcag cttatgagtt actaaaagaa caattggaag
    20521 atgtactaga tacattgact gatcgggaag agaatgtcct tcgcttacgt tttggtttag
    20581 atgatggccg gacgagaaca ttggaagaag tagggaaagt gtttggtgtt actcgggaac
    20641 gtattcgtca gatcgaggct aaagcattaa gaaaattgcg ccatccttct cgttcaaaac
    20701 aattaaaaga tttcttagaa taagcgtgga ctattgacca gaagagaaat cagtaaaact
    20761 gtttggttta ttttaaaaga aaaaaagctt gagactacgc agtctcaagc ttttttttct
    20821 ataggaagga aattcattca ttatttttaa gtaaatccta aaaataagct attggcgtga
    20881 cgtatagaat atgatagatt aaatggtagc gtaaacctag taaaggagcc gatcgctaag
    20941 tgatgaaaaa atgtccaaat tgcggatcga aaaaaatgga gcagaatact atctgtccag
    21001 actgcggtca tcaaataact gcagaagatc agcaaataaa agaatcaatt gaagaaacaa
    21061 atacagatgc agctatgcag gataaatcaa ctgaagatgc agtctttcct gatacagaat
    21121 taaacgatcc aatcgaatgg tcggaattga aagatttacc tctagaatct gtaatggaat
    21181 tattcgaaaa agcagaacca gaagacgaag aaccacctgc tcacgatcaa gtaactaata
    21241 tagagaaaaa tgaacagaag aaagcaactg ttcatgagac ttcggaagaa tcaggaaaga
    21301 atcaagaaga aacgcttgaa tcaaaacaaa aaagaagagt agctgaactg aaagaaatcg
    21361 tcgataatga ggaagaaaat tcgatactat ccgcttatat caaagcacat cgtgaagata
    21421 caaaagaaga gcacgcgaaa gagctgctca aaatgatcag tgaaaaaatt gcacaggaaa
    21481 acaaagtaga gccagaaaag gaacaagaaa ctgaaaaaga ctctgataga gaaaacgcca
    21541 caggtaaaga aacagtaaaa ataaaagacg taaaaacgga tatcacagaa aaaactgaag
    21601 tatttactga aaaacaatta gaaaaggaaa aaacgaataa actgccggaa gcagagaaaa
    21661 aagaaatact cgaaaacaca gacaaaaagt caacagagcc cgatgaaata aatagtgaat
    21721 ccgatgctga aaatcaatct gtaagcaaag agggtactga tcttgaagca aaaatagaaa
    21781 aagaagagaa ccagcctaag ctgtttgaag cagaagcgaa atcaataaca atcgtgccag
    21841 atactgaaaa aacacatcaa gaatcaaact tagaaaaaac agatccagat aaagcgcaaa
    21901 agaaaaaatc aaaaaaagta ccttatctcg ttttagcagc agtacttcta ctcggtggag
    21961 gaagctgggc ttattatgac catcatcaaa aagtagaagc cgaagtagca gcagaagcaa
    22021 aaagacagca acaaatggaa gaacttcatg agaaacttgc tgccttttat acagatgatc
    22081 accatcaatt tattcgtgca gatatgattc atcaagattt atcaaaacta aaaaatgatt
    22141 tatccagtct taagaatgaa aaaggatatt cagagttaga aacaacttac caagatatcc
    22201 aatctaagat ccgagatatc caaaaagtga atgagtggtt catagcacct gccatcgtcg
    22261 atgatcatct agcagatgac atcaagttga aagcagataa agagatccaa gcaatcgaaa
    22321 cggataacac agattttgga aaattgattc aacaagcaca aacagaagct aaaaatcaat
    22381 atgctgaatt gcaaacagct aaagaaaaaa cagctatagt ctttaaagac ggaaaagtag
    22441 tggattcagc aacacgcgac caatacaaga cggcaaaaga agcagtagaa aaagtgaaaa
    22501 atacagatct atctgctcag ttgaatgaac aattgaaaca agtagataag atgctcactg
    22561 ataaagagaa aaaagaagaa gaggaaaaga aaaaagcaga agaagcgaaa aaagcagctg
    22621 aagaacaagc aaaacaagcc gctcaagcag cagctgcagc tcaagccgct caacaagctg
    22681 cggtcgcaca agcagcacag caagaagcgg catcctcgac cccttcctct tcaaactcag
    22741 cgaatcagcc aatcaaatct gccagagcaa gtgatattgc cgatgcatct aatccagcat
    22801 ggacgtgggc accaggtgtc caaagcaaag tgattgctac atgtatccaa cgtggatata
    22861 tcgttgaagg aggttacaga ttagaaaaag ccagaatcga aaatggggaa ggctattata
    22921 atctatatgc cacttcaaca aaatctgcat tgatgaaagg cattggagaa agtgctttgc
    22981 cattttacat cgtaaccatc aactgtaaaa ctggatggtt cggaggaaat gggagcaatt
    23041 aattttaggc aaatgaaaga ggctgtgagc ctgccgttta acaccgttta ttcgaaaaag
    23101 gggagtatga cacaactgtt gtcatactcc ttttttcacc tttccaaacc aaggctcagc
    23161 tattcaagta gataacatta tgttatgata gcaaagaaat gtattaagaa aacctttcac
    23221 tatagaggga gaaaaaaatg aacgatttat tagcaactat atttacaggt attattattg
    23281 atgaaaatga aaaaaactac tttgtccaaa aaaacggaca aacctttggc ttaagcaaat
    23341 cagaaggtga acacaaaatc ggtgaagcag ttgaaggatt cggttaccaa aatcaaaaac
    23401 atgaaaatcg gatcactaca caaattccta aaagccgtat cggtcattac ggttttggaa
    23461 tcgttactgc tacacgaaaa gatttaggtg cgtttgtcga tatcggtctt ccagataaag
    23521 actttgtcgt atctcttgat gaattgccga caatgacaga gctatggcct aaaaaagggg
    23581 atcgcttgat gatttccctt agagttgatg caaaagaccg tatttggggc agtttagcag
    23641 atgaaaaaat attcaaatct ttaagcaaat atggaacaga agaaatgaaa aacaaagatg
    23701 tgataggaac agcataccgc ttgaaattaa caggtacgta cgttttaacg gaagatttct
    23761 atcttgggtt tatccatcct tctgaacgat ataatgaacc tcgtctaggc gagcagataa
    23821 aaggtcgagt gattggtgtc cgaccagacg gtgtactgaa tctttcattg aagccaagag
    23881 catatgaagc tatatcagat gatgcacaaa tgattttaac cattttagaa cgttctgcag
    23941 atcagcaaat caactttaca gataaatcgg atccagaaga aatcatgaaa gcttttggta
    24001 tcagcaaagg agcatttaag cgcgcattag gtaatctttt gaaacaagga ttgattacac
    24061 aagaaaacgg tgtgacaaaa ctagtcaaaa aatctaattg agaatccctt gcatgttttt
    24121 cttaactagc ttataataat tttaattaac atagtgttat atcttttttt atttgtaatt
    24181 attataaatt gttggggttg agtaaatggt catgaatgct atttcggcga tgaaaaaaac
    24241 aaaacagcag ctacatgaag cggggtttaa gctgacaccg caaagagaag ctactctgct
    24301 tgtgcttttg gaaaatgaga aagagcattt atctgcagaa gaaatcttct ttttagtgaa
    24361 aaaaaagagt ccggaaattg gacttgctac tgtttatcga acccttgaaa tcttgacaga
    24421 attgaaaatt gtcgataaag taagttttaa tgatggatta gcccgttatg atttgagaaa
    24481 agaaggcgcc aaacatttcc atcatcattt actatgcttg aactgcggca cgatcgagga
    24541 agtagaagag gatcttttac ttgaagtgga gcaagtagta gaagaacgtt atcatttttt
    24601 agtaaaagat catcggctaa cgttccatgg aatctgtcag gaatgctatg aaaaagaaaa
    24661 aagaaaccag tccgtctgag tgtctagacg gctttttctt tgctcagatt atggaaaaag
    24721 actatcagaa tgaagcggta tctgatatga tagagaggca tgagggggat tattatgaaa
    24781 gagcaaatca acgattatct ccactacttg aatattgaac ggggattgtc cgccaataca
    24841 cgacaaagct atgaacgtga tttggaacag tacttgcatt ttctacagga gcagaaaatt
    24901 gcttcatggc aggatgtcga tcgcttttta gtcatccgtt ttctggagaa gttgcatgaa
    24961 gaaaaaaaag cgacagcaac tgttactcgg atgatctcaa gtctcagaag attccatcag
    25021 tttttacggc aagagcgtat cactgatcat gatccgatgc aacatatcga tacgccgaag
    25081 aaagcacaga aattaccaag tacattgact ctgacagaag tagaaaagct gattgaagca
    25141 cctgatacga caaaaacgtt agggataaga gatcgtgcaa tcttggaagt catgtatgct
    25201 actgggatgc gcgtcagtga attgattgga ttgaaattgg gagatcttca tctttctctt
    25261 ggactggtac agacagttgg aaaaggagat aaagagcgga tcattccttt aggtgattat
    25321 gcgatccaat ggctggaacg ctacttagac gaagcacgtc cattacttgt aaaggacgca
    25381 tctgaaatgc atgtatttgt caataatcat gggaaaggtc tttctcggca aggaatctgg
    25441 aaaaatctga agcagttagt acgagaggct gggatttaca aagaagtaac accacatacg
    25501 ctgcggcata gctttgccac acatctgcta gaaaatggag ctgatttgcg gacagtacag
    25561 gaattgttag gtcacgcgga tatctctacg actcagattt atacacatat cacgaagaaa
    25621 agaatgacgg atgtttataa gcagcatttt ccaagggctt agtcatagga aggtgagaag
    25681 atgttaacac attaccggaa agaaaaccgt aaaattgcta tgggactatt gagtttccat
    25741 aagaaactga caggtaaaac ttctttgttg aaggagattg atacgtacga atctgaagac
    25801 gattatgaac tttttttctt tacgccagaa ggttcaacca acattcaagg gattattggt
    25861 atttactggg caacgaacga tcagctgatc atccatgaca tttctttgaa tccgtcttat
    25921 cgcggtgaga atatgggctt tcaaatgtta gatgaattac aggaaaagta cccggatgtc
    25981 tccatccgtg caactgaaat cacagagcct tacattggaa aatggctagc aaagaaaaag
    26041 aagaaagagt gaatgagttg acggagatca atattaaatt agatgtattc gagggtcctc
    26101 tcgatctgct gcttcatctg attcagcaaa tggaaatcga tatatatgat ataccgatcg
    26161 ctacgatcac ggagcaatat atgaattata tccatacaat gaaaacactc gagctagctg
    26221 ttgcaggaga atacttagtg atggctgcta cattgatggc aatcaaaagc aagacattgc
    26281 ttcctgtcca agaattcgtc acagacgatg aagaattatg ggaagaagat cctcgagaag
    26341 aattggtcac tcagctttta gaataccgta aatataaata tgcagctgaa agactgacag
    26401 aaaaagcaga ggaacgaagt ctttattaca caaaagaacc tatgaacatc gatgggttag
    26461 cggatgctga aaagccgttg aagcgaggac aagtcaaaaa aatcgatttg atccgtgcca
    26521 tgcagaaaat cttagaacgt aagaaatttt ctcaaaaagt ggaaaaaacg atcacgcccg
    26581 atgacacaac gatcgaagaa cgaatggtat ttatcgaaga gcgtataaaa agaaatgcgc
    26641 atggctgtac tttcgattct ttttttgagt caccttctaa aagtgaagtt gtcactactt
    26701 ttatggcttt gctagaattg atgaaaaaag ggcagatcat tgcgcaacaa aaagaaaact
    26761 atgaatcaat tatgctttat ccagcagtag gagataccga acatgacgaa attaagtgaa
    26821 cttgaagccc ttctttttat tgttggcgag gaagggatca gtaatgaaga attaagcgga
    26881 ctgttaaatc tcagcgaagc agaagtcaca agtttagtga aagaattaaa agaatcttac
    26941 actcaaaact cgcactcagc tttgcatatt tttgaaacgg aaagccatta tgtattaacg
    27001 actaaaaaag agctggctcc cttacttaag cgatatgcgc aagggacatc aaacacatta
    27061 tctcaagccg ccgtcgaaac cttagcaatc atcgcttata aacagccaat cacaagagct
    27121 gaaatcgagc agattcgagg agttcaggtt tcaggagcgg tacagcgtct agctgcccat
    27181 aaactgattg aagaaaaagg tagagtagaa ggaccaggtc ggccgatatt atatggaaca
    27241 actggctact tcttagatta ttttggtttg aaatcattag aagaactgcc tgatacacaa
    27301 gaaatggaaa tttcacttga agaagacgtg tcaccagatc tattctttga tggaatgaat
    27361 aaaggagaat aattgtaatg gagagattgc agaaagtaat tgcccacgct ggcatcactt
    27421 ctcgtcgaaa agcagaagaa ttcatccttg caggacgtgt aaaagtaaac ggacaagttg
    27481 taagggaatt agggataaaa gttgggaaac atgacactgt ggaagtggat gaagtcccaa
    27541 tttatcaaga agaatacggt tactatttat tgtacaaacc taaaggagtt atttctgctg
    27601 ttgcagatga caaaggaaga aaagttgtta cggatctttt gccgatggta aaagaacgta
    27661 tctatcctgt aggtcgactg gattacgata cttcggggat cttgctactg acaaatgatg
    27721 gagattttgc tcagcgcctg acacatccaa aacatgaagt ggataaagtt tacgttgcaa
    27781 aggtaaaagg gatcgctaca aaatcgatgc ttgcaccttt gacaaaagga ataaagatcg
    27841 aaggacgaaa aacatctcca gctaaattcc aaattttatc agtggatcct aagacaaacc
    27901 acagtatcgt ggaattgacg atccacgaag gacgtaatca tcaagtgaaa aatatgcttc
    27961 aagcagttgg tcttcctgtg caaaaactaa aacgtgaaaa atacggagat ctgactttac
    28021 aaggcctacg tcctggggat taccgtgaac tgaacaaaaa agaagtcagc agtttgctga
    28081 accactcaaa atgaacactt actttttata agtgttagat gttgcgtttt ttgaatagat
    28141 atgtataatg aatatgtaaa caaaaattat ataaggttcg tcttcagggg cagggtgaaa
    28201 ttcccgaccg gtggttatag tccacgacct attttgcaaa aaaatagctg aatcggtgaa
    28261 attccgatac cgacagtata gtctggataa agaagataga gcttatttga cgacgcttga
    28321 tcaaataact ctaactctat tttccctgga aaatagagtt ttttcatttg gagagaaacg
    28381 tcaaaaagtt cgctgaagag gagtcctaac aggaggattt caaatgaaga acacccgtgt
    28441 acagaaaatg gttgcagtag cgatgtttgc tgcgatcgca ttagttttac agtattttgc
    28501 ttttccgatc atgccggctt ttagtttttt gaagatcgat tttagtgata tctcggtatt
    28561 gatcagcatg ttcttattcg gtccagcggc cggagttgca acagcgttct tgcgttcagt
    28621 attacatctg ctgactacag gtttttctcc ggataatttg gtaggagaca ctgctagttt
    28681 cttatcaaca acgatcttta cattcccgat ttattatttc tttagtgtaa agaaacagca
    28741 taaaggaaga aacaaatttt taggtgtcat tacaggaacc atcgctctaa ctatttttat
    28801 gagtatcgca aattatttcg ttattacgcc tctttactta atgtttttag ggctgaacgc
    28861 aacacagatg ctgggcatgt ctttagcaaa ctatgtactg attgggatcg ttcctttcaa
    28921 cttgatcaaa ggattcatcg tgagtgctgt ctttttagtg ctgcatgcgc aacttcttcc
    28981 atggttaagt cgaaaacaac atcagttcga acaacgtcat acagcagtca aataaatatc
    29041 aaaaagatca agaaatttct tggtcttttt ttttggaaaa aaatacaaga catgcaataa
    29101 tgtaaacgtt ttatttgttt gttttgagta tttttttgat ttatgcataa aaatcaatca
    29161 attctttgca aatgtgaaat tcttctcctt ttaaaagacg aaaatgtttg tttataaaaa
    29221 aaaggaaacg ctacaatgaa aaagaagaaa gctttaaaaa cctgaaaaaa gaggagggaa
    29281 tagggaaaaa cgaacttttt gaacaaaagt tttacaaaat gcgtgttatt atttttgttc
    29341 tgatactctt tttgataaaa taacattaga gccaaaattg ttgtctctaa cggaaaagaa
    29401 aggaagaaga agatggaaca aacaaaaaag aaaaaatttc aaatgccttc agcgtatacg
    29461 gtcttattta ttattattgc agtaatcgct gtacttactt ggtttatacc agctgggcac
    29521 tatagtgtag acgatgcagg caacatcgtc gctggatcat atgaacgagt acaacaaaat
    29581 cctcaagggc tgtgggatat tttcatggcg ccaatcaatg ggatgctagg tgtaccagcg
    29641 ggggagctaa ctaaagaaac acctgctgca atcccaatct ctttcttcat tttggttgtt
    29701 ggtggatttt taggtattat caacaaaaca ggggcactag atgccgggat tgcttcagtt
    29761 gtgaagaaat tcaaaggaaa agaaaaaatg cttattccag tattgatgct gttatttgca
    29821 ttaggcggct ctacttacgg aatggcagaa gaaacgattc cattctatgc tttactgatc
    29881 ccagtcatga tggctgtagg ctttgataca gtagtagctg tagcaatcgt attagtaggg
    29941 tctcaagtag gctgtctagc ttcaacggta aatccttttg caacaggcgt agcttcacaa
    30001 gctgttggga tttcgatggg tgaaggtatt ggtcttcgat tcttgatgtt cgttattttg
    30061 ttagctattt ctattgtata tgtgtatcgt tatgcatcaa agatcgaaaa agatccaaca
    30121 aaatcattag tatacaacca acgtaaagaa gatatgaagc atttcgatat tgaagcaatc
    30181 ggtcgtcaag aagtaatcac gaaaaaacaa aaacatgtta atgtattgtt ctttattact
    30241 tttggtatca tgatcatcag tttgattcct tggacaacct tgaatgcgaa tttcacgatt
    30301 tttgaatcat tgacaaactg gttaacaaac cttccggtac taggtacggt tctaggtaaa
    30361 agcatgcttc cattaggtga ctggtacttc ccagaaatta ctatgttatt cttagtaatg
    30421 tccatcgtag tagcaatcac ttatggcatg aaagagtctg aatttgtctc tgaattttta
    30481 gctggtgctt ctgatttgat cggtgtagca atcgtagtag ctgttgctcg tggtatccaa
    30541 gtggttatga acaatggatt aatcacagac accatcttac attggggcga acaaggatta
    30601 agttcattat cttcaagtgt attcatcatt attacattta ttttctatat ccctatgtca
    30661 ttcttgattc cttcaacttc cggcttagct gctgcaacaa tgggaatcat gggacctatg
    30721 ggtgaatttg ccggcgtcgg taaggattta gtaatcactg cttatcaatc tgcatctggt
    30781 ttagtaaact taattacacc aacatctgct atcgtaatgg gtgctgtagc aattgctcgt
    30841 ttcgatgttt cagtgtggtg gaaatttacc ggtaaattaa ttgcgatatt atttgtagcc
    30901 atctgtgtga tcctaggtgt agcagcaatg ttctaaacct agacaaatac aggtacaagg
    30961 tctatcataa gaatgaagaa accgataaac ggctatcgat aagcacgtgg ataagtcaat
    31021 agctccattc agtgagtgtt ttttctttca tcatttgtta agaacattct gcttgctgat
    31081 ggagcaggct taaaacgtca ttatttgaga agaagaggtt gtgtcggagg aatttgacat
    31141 gacccttttt aacatattag gaggataata tcatgaaaaa atttgtgaca gaacaacatc
    31201 atgaacaagc attagaatca ttgagcgaat tgatccgaat tccttccgta ctagatgaag
    31261 cagattcagg acaaggacat cccttcggta aaaaagtgat tgaagctttg gataaagtat
    31321 tggaaatcag tgaaaagcta ggatttagaa catttaaaga tccagaaggc tattacggtt
    31381 attcagagat tggctctgga gatgaattat tcggtatctt gtgtcatatg gacgttgttc
    31441 cagcagggga cgaaaataat tgggaaacaa aaccattcga tccaactata aaagacggct
    31501 ggttagttgg tcgcggatcc caagatgaca aaggtccttc tattgcggca atgtatgccg
    31561 tcaaagcttt gattgatgct ggcgtggaat tcaagacacg tattcgtttt atctttggta
    31621 cagatgaaga aaatttatgg cgttgtttag aaaaatataa cgaaaaagaa gaaggaatta
    31681 cgcaaggatt tgcgccagat gctgaatttc ctttaattta tgcagaaaaa ggcttattgc
    31741 aagcttactt gacaggacca ggaacgaacg agttttctgt aaaagctgga ggagcgttga
    31801 atgttgttcc tgatgcagct ccttactctg gagaaaagct ttctgaagta aaagaagcat
    31861 tgaaaaaaca cgaattcgat ttcgaagaac aaggtgaagg catcgtcgtt cttggtaaaa
    31921 gtatccacgc gaaagatgca gcacaaggag tgaatgctat ttctcgtctg gcaattgctc
    31981 tttcagaagt atttgatttt ggcccaatca atttcttagg aaaattagtt caagaaaatg
    32041 caactggtga agctgtcgtg ggcaaaacag aagatgaaca atccggcgag ctaacgatga
    32101 actttgcaag tttggaaatc acaccagaac aaacaaaaat cggtgtagat atgagaatcc
    32161 ctgttacatt caagaaagat gatttagtag ctaaattaac taaaacagca gaaaaatatg
    32221 ggttgactta tgaagaattt gacttccttg attcattata cgtgccacta gacagtgagt
    32281 tagtgaaaaa tctattgggg acatatcgcg atattactgg agacatgact gaaccgtttg
    32341 tatcaggcgg cgctactttt gctcgtacga tgaaccagtg tgtggcattc ggtgcgatgt
    32401 tccctgatac tcctgacttt atgcaccagg cgaatgaacg atgggaatta agtagtatgt
    32461 ataaagcaat ggaaatttat gcagaagctg tgtatcgttt atgtgctaaa taaaaataaa
    32521 catacaaaaa gggcggatat tcaaatggat attccgtctt tttttatttg atgctggaaa
    32581 gtttgcattt ctctcttatt tttttaaggt ataatcatac ttgattaaga aaaaggggtc
    32641 actcagatag aaaaggtggg agaaagtgaa aatatttaga cgaatactaa ttggcttagt
    32701 catcatttta ggattactcg gtggagccgg ttattactat atacagcaaa atacgtacga
    32761 accatcgtca gaagcgcaag tgttggtaaa agaaggaaaa aacaaagaag attacttatt
    32821 ttttgaagga gagaaaaaga atcatggaaa gtctccatta cttatttttt atcctggtgc
    32881 tctcgtagag ccagaaagtt atagtatttg ggcgcaagat ttagcaaaaa acggcttttc
    32941 agtcgctatt gtcaaaatgc cacttgatct agcagtgatg ggcggaaaca aagcggataa
    33001 ggtcaaagaa gattttccaa attccgatta tgtgatcggt ggccattcat taggtggcgt
    33061 aatggcaagt cgttatgtca ataagaatca ttcagacaaa catttaaaag gggtattctt
    33121 catggcaagt tatcccgaca aaaaaggaac attgacagaa tcagctgttc ctgttttatc
    33181 gatcacggcg acaaaagata aagtattgaa tcaggaagct tatcaagaag ctaagcagta
    33241 tttaccggaa agaacagagt atgtatcaat caatggcgga aatcatggag gttttggcag
    33301 ctatggtgag caaaaaggag atggagaggc agaaatttct aacgcagacc agcaaactgt
    33361 gatcgtcaat acattggaaa actggctgaa aaagttgaaa taatataaat gggtcctata
    33421 gggtccgtga aaaaactagt caattaacta tagatagcaa atgaatcttt caaaataagt
    33481 cgggatttca cggaacaaga gaaacagatc ccggcttatt ttcaagttta gagaacttag
    33541 tgtacgtttt taaagtttcg tttatattta tattttattt tctaataaaa tcgctcgaac
    33601 tggacatttt tgatacgctt tttttacata tgtttcttct tccggcatca cgaactgttg
    33661 atgagcctct ggttcttggg caaataaaac gattccttct tcatcataat cgaaaatatc
    33721 tggcgcttcg atttgacaaa gaccgcatgc aatacagcgt tcaggtacaa gtttacatag
    33781 tagtgacatt tctaaccatc ctaacttaag gagaataata tgattgtttt tattttatcg
    33841 ctattttcat caggacacaa gctgcggatt agttctcttt accaactcct tgtgggaaaa
    33901 cgaacgactt cagtacttat ttatggattt acccacgaac ttttgtttat ccataacagt
    33961 tttccagaat tgaagcagga taagttttat caaattttgc aaaaaattgc gcagcaaggt
    34021 tggatcgaaa taaatgaaaa tgaagcaaag ctaacgcctg caggggctga tatgttgtcc
    34081 gaacatcaaa tagaacatac tggtttgcgt tttgaccgct atggcagaac aggggaaact
    34141 agttggcggc tcattaaatt tgctgttcaa gtaatttcta atctggcaac gggtattcaa
    34201 gactatcttc cagcagagac aagtcctttt tatactttcc aactaaaaaa atggcttagt
    34261 gaaagccaat tgccacgtga aattttgatt gatactgcgt atgagagttt ggtgcagctg
    34321 ttttcggaga taccagaaga agcagcagat tttttagcta accaattatc tggaaatgag
    34381 cgaacagggc tgcttcctta tcagctggca aaaaacaatg atgagtcagc ggtttatctg
    34441 caacaaagca gatgtatcca ccttttgtta gcacaaatcg aaaaacggcc agattcgctt
    34501 tggcacgctt tgatcgattc attattacag caaaatttca atcaaagcat gatgatcacc
    34561 aagcagatgt ttatgaatgg tcagacaatt gaccagatca tggcaatccg tcatttaaaa
    34621 agaggaacag taacagatca tcttattgag tgggccttgt tttttgatga ttttccatac
    34681 gagtggattc tctctgcaga aacaatcgaa cgtttggaac caaataagga ttccgtgcga
    34741 gagtggcgct ttagcgaatg gaatgtagat ggacaattag attatggaga atttcgtttg
    34801 tatcaaatct atctattgag aaaggaagcg atacagaatg ttaataaatg aattaaaaaa
    34861 atattttgga tttgattcat ttcgtcccgg ccaagaagaa attattcagg cgttgcttga
    34921 tggagaagat actctcgcta ttttgcctac aggaacggga aaaagccttt gctatcaatt
    34981 gacggggtat ttaatggaag gtctggtcat catcgtgtca ccgctgcttt ctctaatgga
    35041 agatcaagtg acgcaattac aaaaacgagg ggagaaacga gtagctgctt tcaatagttt
    35101 actttcgcaa tctgaaagaa gatacgtcct ccgtcatcta tcgcaatata aatttttgtt
    35161 tttgagtccc gaaatgttga ctaatccttc tcttttagag catctgaaaa aacaaaatat
    35221 tgcgttatat gtagtagatg aggctcattg cgtgtctcaa tggggagttg atttccgtcc
    35281 agaatatcaa cagttaggaa aaatccgaaa gcttttagga aacccggtca cactggcact
    35341 aacggcgaca gcaacagatt tagtagcaag agatatacgt catgtactat ttgatcgacc
    35401 accaaaagag atcagacaat cagtcaatcg gcaaaatatc tcgctttttg ttcggaaaac
    35461 gcagcaaaaa gaacaagaac ttgaacactt catggaaaga gcacaaggag cggcaatcat
    35521 ttattgtgca acaaaaaaag aagtcgaacg attgtatcat ttattcaggg aacgttttac
    35581 agttggatac tatcacggtg gtcttgatgc agctcaaaga agacaacttc aacagcagtt
    35641 tgtaaaaaat cagctgcagt ttctcattgc tacgaatgca tttggtatgg ggatcgataa
    35701 atctgatatc cgttatgtgg tccattatga tttgccagac agtctagaaa actatgtaca
    35761 agaaatcggt cgagcaggca gagatcagga agaaagtgca gcaattcttt tttatcaaag
    35821 tggggatgaa cgtatccatt atttctttaa tcaactttct agagaacagc gacaaagttt
    35881 tgagctttat ttggaatatg ccacagagca agctcccttt gatgagctgc aaaaaaaatg
    35941 gatggagctg atccagcagt ctgaaaaacc agaaaattgg gtggaacggc tcaaacgtca
    36001 ggaaaaagaa aaagaattcc gcctgcagca gatgcttcgc tatattaatg aagaaaactg
    36061 ccgcagaaaa ttcatcttag cttattttgg cgaaaaactc tccgaaaagc cgcagaattg
    36121 ttgtgatatt gatggagcaa aagcagaact tctgccaaag aggaagcttt tttctaagac
    36181 tgaacaactt cattgggaaa cgattttact aaatttattt aaaaaaaaca tggaacattg
    36241 attttttagg acaagacact ttttcctatg gtataataca cacgatagag tttaggaggt
    36301 aaaacagtga gcagaaaaga tagacatcaa tctacagaaa ataacgaaac acaagaacca
    36361 tgggaacaac caatctacga tacagatgat gaagtttcat caagaagttc tcagagacaa
    36421 caaaagaaag gaaatacatt atttctttcg ctatttttga ttttactggt cttatgtatc
    36481 gctattccag caggtgctta tttctggatc agaaatggat caagcaacaa tgcaacagca
    36541 gcaacttctt ctgaaacttc gacatcagta gtagaaagtt ctacaagtac aacaaaagag
    36601 gagtcaactg agacttcaac agtagaatct agtacaatcg cggaagaatc tactgtgtct
    36661 caagatacag gtgtaacgtc agaaagcagt attgcagcag agacaacacc gacttcctca
    36721 agtgaggcaa cttatcaagc aggggattca agcagcaatg cagcagaaac aacaccttct
    36781 tcatcagctg cagccggttc aacaacgact gttcaagcag gcgaaggtcc aaaacaagtg
    36841 gctgagcgtg cagggatcac cactgatcaa ttgtttgaat tgaatggctt agatccaaac
    36901 aactttatgc tttaccctgg tcaagaatta agaattaaat aataatagcc gcgctttgcg
    36961 gctttttttc tgagaaaaag gagttatatc atgacacaaa tcagtattgc aatcgacggg
    37021 cctgcttcat ctgggaaaag taccgttgcc aagatattag caaaagaatt gaattatatt
    37081 tatacagata ccggtgccat gtatcgcgca gtaacttatt tagctattac gaacaatgta
    37141 tctttttcag atgaagaagg gctagtttcg ctgatcaaaa agtatcctat ctctttttcg
    37201 caacaagaag atggacagca tgtattcata gcatcaaaag atgtgacttt agaaatccgt
    37261 caaccagatg tcacaaaagc tgtttctgaa gtctctgcac atggaaaagt cagagaagaa
    37321 ttagttgctg tccaacgaaa aataggggaa cgcggtggcg ttgtcatgga cggaagagac
    37381 atcgggacag ctgtattacc gaatgcagaa gtgaaaatct ttttagtagc aagcgtaagt
    37441 gagcgtgcag aaagacgttt caaagagaac caagaaaaag gaattccgac tgatcttgaa
    37501 acactgacga aagagataca ggaaagagac cattatgatt caacaaggga cgtctctccg
    37561 ctgaagcaag cagaggatgc tgttcgtatc gatacgactg gcaaatcgat tccagaagtc
    37621 gttgcagcaa taaaagctgt tgttttgaaa aaaggttatc ttctttttta aattaagaaa
    37681 aaaaatgaaa aacaattgtt ttttcaagga aaacgaacga aatcgcttta ttttttttga
    37741 ataatcaatt aaactaaaaa cagtaccgta cttacggcag aatgttggtt aggaggacaa
    37801 gtgttatgac agaatttgat caaaatcaag agaacaacca gtcaatggaa gacgcaatga
    37861 aaagcgtaca agaagtaaaa gttggcgatg ttgttaaggg cgaagtttta gtcattgaag
    37921 acaaacaagt gattgtcgga atcgaagggg ctggagttga aggagtcgtt ccggcaaaag
    37981 aattatcaac tttgccggta gaagatatca gcgaagtagt aaaagtcggt gatgtattag
    38041 atttagtcgt tatcagtacg atcggcaaag ataaagaaaa cggcagctat ctactttcaa
    38101 aacgccgttt agatgctaaa aaagtttggg aagatatcga aagagatttc caagagggca
    38161 aggtcatcga agcacctgtt acaaatgttg tcaaaggcgg tttagtcgtt gacgtcggtg
    38221 tacgtggttt tgtccctgca tcaatggtgg aagatcattt tgttgcagac ttttcagact
    38281 ataaaggcaa aacattgagc tttaaaatca tcgaaatcga accatcagaa aatcgtttga
    38341 tcttatcgca taaagcggta gtggaaaacg aaagagaaga aaagaaaaaa gaaattcttt
    38401 caactatcca tgagggagat gttctcagtg gacgtgttgc acgtcttact gattttggcg
    38461 catttgtcga cctaggcgga attgacggtc tagtccatgt ctcagagatt tcacatagtc
    38521 atgtagcaaa accaagtgat gtattggctg tcaatgatga tgtaaatgtc aaagtgttgt
    38581 ctatcaatcc tgaacaagaa cgtgtttcct tgtcaatcaa agacacacag cctggacctt
    38641 ggtcagaaat cgatacaaaa gctccagttg gcacagtatt agacggaaca gttaaacgtt
    38701 tgacaagctt cggtgccttt gttgaagtgt tccctggagt agaagggcta gtccatatct
    38761 ctcaaatttc acataaacat attgcgacac cacatgaagt gcttcatgaa ggtgacgaag
    38821 tgaaagtgaa agtattagag atccatccag aagaacatcg tattgcattg agtatcaaag
    38881 ctttagaaga aaaaccagct tcagaagaag aaccaaaaaa tgttgagtct tatgaattac
    38941 cagaagaaaa tactggattt actatgggag acattttagg tgatgcgttg aaagaagaag
    39001 tagaagaaaa agcaaccgat gattctgaaa aataattgat tttgtatctg tgactgagat
    39061 gaaagcagct gcttttgtct cagtttttct tttgaaaagc gattagtatt tcaataagga
    39121 ataaaaatac ttcgtttaat tgacaatcta tgcttgaaag ttggcaatgc attcgttaaa
    39181 ctaagtgaga ttggaaactt gtgaggagga aataatatgg caaatccaac aattgcaatc
    39241 gttggccgcc cgaacgtcgg taagtctacg atttttaacc gcatcgctgg tgagcgtatc
    39301 tcgattgtcg aagatactcc tggagtaact cgtgatcgta tttatgcaaa aggtgaatgg
    39361 ttaggtcgag aattcagcgt gatcgacaca ggcggaattg atcttggcga tgaacctttt
    39421 atggatcaga tcaagcatca agcagaaatc gcgattgaag aagcagatgt aatcatttgt
    39481 gtagtcagcg gacgcgaagg cgtgacagac gcagatgaga tggttgcgaa aattttatac
    39541 agaagtaata aaccagtgat tttagcagtc aataaagtag ataatccaga aatgagaaac
    39601 gatatctatg aattttattc cttagggcta ggcgatcctt atcctgtttc aggaagccat
    39661 ggactaggga ttggtgatat tttagatgaa gcagtgaagt atttctctga agagactgaa
    39721 gaagaggacg acgacacgat taagtttagt ttgattggtc gcccaaatgt tggtaaatcc
    39781 tctttgatca atgcgatttt aggagaagaa cgtgtaattg tttcggatat tgaaggaacg
    39841 acccgagacg caatcgacac ccacttcgtt tctgaaagtg gtcagaaatt cttaatgata
    39901 gatacagctg gtatgcgtaa acgcggaaaa gtatacgaaa atactgaaaa atacagcgtg
    39961 atgcgtgcaa tgcgtgccat tgaccgttct gatatcgttt tgatggtact gaatgctgaa
    40021 gaagggattc gggaacaaga caagcgagta gcgggttacg cccatgaagc tggtcgtgga
    40081 attattatcg tcgtgaataa atgggatctt gtaaagaaag aaaccaatac aatgcgtgat
    40141 ttcgaacaag agattcgtga tgaattccgg tatcttgatt acgctccaat cgtttttgtt
    40201 tctgcagtga ctaaacaacg gttggaacgt ctgcctgaaa tgatcgaaca agtaagtatg
    40261 aaccagaatc ttcgtatctc ttcggctgtg ttgaatgata tcattatgga tgctgtagca
    40321 atcaatccaa caccaacaga taaaggaaaa cgcctgaaga ttttttatgc tacacaagtc
    40381 gctgtcaaac cacctacatt tgtcgttttt gtcaatgaag aggaattgat gcatttttct
    40441 tatgaacgtt tcttagaaaa tcaaatcaga aaagcattta cttttgaagg gacgtccatc
    40501 cgaattatcc ctcgtaggag aaaataggca ttttaccata tcgacgtttt tttttcaaaa
    40561 gaaaaagaca gtttcgtttg ttacgtttct atgactaaaa aaagcatgtg aaaattggta
    40621 aaaaccttgc tattaagcgg ttcatatgat atcgtgataa cagaatattg aagttaatca
    40681 atatttcttt ttaaacttct ggaccactca gaaagtttta actaaatgat atttctatca
    40741 tatctcttgt ggaggaggtg aatctatcca tggcaaacaa agcagaatta atcgaaaaag
    40801 ttgcttcagc tactgattta actaaaaaag atgcaactgc agcagtagat gctgtatttt
    40861 caactattca agatgcttta gctaacggcg aaaaagttca attaatcggt tttggtaact
    40921 ttgaagttcg cgaacgcgca gctcgcaaag gtcgtaaccc acaaactggt gaagaaatcg
    40981 aaattccagc tagcaaagta cctgcattca aaccaggtaa agcattaaaa gacgctgtta
    41041 aataagacag ttgaaaaagc gcttgtggct ctagggctac aagtgctttt ctttttattt
    41101 cctagcagaa aaggaataaa taagagacag agattccgaa tccgtatgtc atacatagaa
    41161 aacacatgta ttttatttaa tttttattta tttgcaagtt atgaggtgag ctttgctctt
    41221 atcttttcta gaatttgctt actaatggta aaataaaaat aagaagagga gggatgcgta
    41281 tggaacttga ttatcaagta gaagatgcgt tgacgaaagt gttttacgga gaaacgctag
    41341 tcagtcagct aagagaactt tccattgatc agccaatctt atttttaacg aatcagcgct
    41401 attatgattt gtttgcagat aagatcaacc cgttatttgc aaatcaagca aacaatgact
    41461 ggtatatttg tgccaacact caatgcaatc atttaacaga attaaagaac ctgcttgatt
    41521 tcgtcaaacg ctatcccgaa aatcaatcca tgtttatcat cggatttgga aatgaaggga
    41581 tcatggatct ggcaggtttt tttcaaaaac atacaaccct tgattcatca ctatggatga
    41641 tccctgtatc gatccgttct ctaagccgag cattaacacc gcagcggacg attttgcagc
    41701 taccaaatcg tgtagtgctg caaaccatca atctgccaga acgcatcgtt tatgatcaaa
    41761 caatcagcga gcggcaggtg gacggaaagc agattgactt tttgactttt atctgttgcg
    41821 gaatgatttg tgatcatcgt tttttgcaaa atctgtataa aaactatcca aataaaaagc
    41881 aattaacgac tcggccgttt gccgggatga tcgaagaaat gatctatttt tatcaattag
    41941 aggcagaaaa cctgtcaaat tatggtaaac tgtttgaaca agctttttat ctgaccgaaa
    42001 atggccatct actttctgct agtatgaaaa aatttttagg aatgatgttt catttcgtgt
    42061 ggaatctcca agcatatcct tttgatttcc aactaaaaaa cttttttgtg tggctggact
    42121 tgcttggcta tccaatccac tggctggaac agatttcaaa gatggagtat ttggaaaaag
    42181 ttcttttttt ggcagaaaaa agcaaaaaaa tacttgtttt agaaaaaata ggtataatag
    42241 acggatacca acatccaaac gaaaaagaat tattgagaac aatgacggta tttcaacaaa
    42301 tcgtcagtga gataagaggg aattgaaatg aatacaaata gcgaaaaaat gttgcaagct
    42361 ttatcagatg aagacttgtc acaagcacaa atctttttag aaaaagcatt aaaagaagac
    42421 ccagcagata tattagctga actaggcgaa gaattgctgg ctattggctt tttgatcgaa
    42481 gcaaaacaga tttttgaaca actgatcaac caatacccag aaaatgacgg actgaacatc
    42541 ccgttagcag aaattgcaat cgaagataat gagatcgact tagcttttga atacctggaa
    42601 aaagtggata agcaaagtga ttactatccg caaagcttat tggcgatagc tgatttgtac
    42661 caagttatcg gaatccctga agtgagtgaa gcaaaattga aagaagcagc tgggttgctt
    42721 cctgatgaac cattgatcca gtttgcgcta gctgaattgt atttttcagt tgatcgtttc
    42781 aaagaggcag cagtggttta tgaaacattg ttggcaagcg ggataaatga aatttcagga
    42841 atctcgatgc aggaacgttt aggacaatcc ttaagtatgc aaggagaatt cgaagcagct
    42901 atcgtacctt tagaagaagc actgaaagaa gaaaggacag atgatcgact gttccagcta
    42961 gcttttacga atcttcaatt gaaagaaaat cagcaggcaa tcaactatct ggaagaactt
    43021 cgagaagtta atccgcatta tcaatcgtta tatctatatc taggacaagc tcttcaagaa
    43081 gaagaaatga ttgaagaagc acaaacagtg ttagaagaag gaatcaaaga aaatccttac
    43141 caagtcgaac tttatcacct ggcctcggaa aatgctttcc gtctgcatga tagacagcga
    43201 gcagaagaac ttttactgaa agctttagaa gtaggagaca aacaagatga aacattactt
    43261 actttaagta atctttactt ggatgatgaa agatatgaag atgtgataca agtgatcaat
    43321 cagatggaag aaactgctaa tccttatgca gaatggaacc tagcccatgc ttataatgaa
    43381 ttagaagact ttaccgttgc agctgtacac tatgaacagg cttatcatga actatcacat
    43441 gaaccagatt tcttgaaaga gtatgccttt ttcttaagag aagaagggca gctgaaaaga
    43501 gcgcaagaat tattgactta ttatttaaca cttgaaccag gagatatgga ggcactgtca
    43561 ttattagatg acctaacaga gaggtgagaa aaatgctaat tgatgtacgg gaaaagaaga
    43621 attttttaac gtggatggtc aatcatgtat cttttagccg aagagaagtt ttttggatct
    43681 tgaattatct tgccaatcat gaagcgattt taagcaatgt ccactttgtt gaaggggcga
    43741 attttgcgga tcgaggactg cagatcagtg atctatctgt tgaaggggaa cccatgaaat
    43801 tgtttttgca gggaaaagaa tttacggaca cagaccagat ttttcatgaa atccgtttga
    43861 attggaaaaa gcctttatat gtggaatgta tattcgaaaa tgcttggcag acaagagaat
    43921 atctatctat cttagaagac aatccatttt cttcttggga ttcttcagtc agtgaagaag
    43981 atactgaatt aattgaacga tattttcaag aaaaagaaga agaggcaaaa ctaaaaatgc
    44041 tttatgctca aatcgatcaa gcactagaag atggagatag ggatgctttt ttgaaattat
    44101 ctgatgaagt taaccgaaag atccttttgc agacacaaaa gaaaagtaac cgggtaagtg
    44161 aacataacaa ttagttaaaa atagtatagt actaaaaaag acaaaggtca gctggatgtg
    44221 gaatctttcc tcatagccta tctttgtctt ttttcttata gttttttcag taatcttgtc
    44281 tgtggcttca aataagtaaa gccttgccct tccacttcat gcacattgat gattgaaagg
    44341 aaagcttttt cgtcaatctc gtggacgatc ctcttagctt cagttaattc actagagcta
    44401 acgaccatat agatgatttt ttttgaatta ccagagaatg cgccttctcc agaaaggaaa
    44461 gtcacacctc tttgcagacc ggtcatcagt agtggtgcaa tctcttcgct tttgttggag
    44521 acgacaagta gaccttttgc agaatatccg ccatctaaga tcgaatcaat cacacgactg
    44581 aaaacatacg aaacaatcaa cgtatacatc atacgtttca agtcgatata ggttaatgaa
    44641 gcaagtaaga cgatgatatc aaatgccaat agggaacgcc ccatagtgat gccgtaattt
    44701 tgttctaaaa tccgagcgat aatatcactg ccgcctgttg ttccacccat gcggtagacg
    44761 atcccgcttc ctacacctgc aactaaaccc gcaagtagag aaacgatcag tagatcatgc
    44821 tgtaaattga tttctagtgg aaccctttgc cagatccata aaaagaatga caaagaaagt
    44881 gtacctagaa cagtataggc caaggaacgt ttaccgagga tctttcctcc tagtaaaatc
    44941 aatgggatgt tgattaataa agtcgtataa gctggatcaa taccaaataa agctcttaag
    45001 atcaaggtga tccctgagac tcccccttct gctaaatgat tagcgatgtt caagtaaaca
    45061 agaccaaatg cataaatact tgttcctata atgataaaaa gaacttcttt tactgttttt
    45121 cgtttgacca tatgaattcc agctttcaat tatgtatttt cacagaattt ccatttagaa
    45181 attccttcct aaatgtagca tggaaattcg attttctcaa ttgctcttat ctaggatttg
    45241 cgttaaagtt ttggtaagat agttttggag ggaaaaagat ggataaaaag cgttctttat
    45301 acagtatgca gcaggaagtg gatgaatata tccagcaatt caaggtgggg tatttctctc
    45361 cattagctca gatggctcga ttaactgaag aagtaggtga attggcaaga gaagtcaacc
    45421 acacttatgg agaaaaaagc aaaaaggctt ctgaaccagt taactcggta gcagaagaac
    45481 ttggtgatgt tttattcgtt acgatgatca tggctaattc attgaatatc gacttaactg
    45541 aagtttttga aaaaaacatg gaaaaattca atcaaagaga ccataatcgc tttgagcgta
    45601 aggacgagta aacaagatga agtggtcctg gccttgaaga ctctgaaacg gacttgtcaa
    45661 acagtcacca tgcaactgag tctttatctc aggacaagaa acacgcagga aaggttggaa
    45721 aaatgaaatt aaaacaatta cctctggaat accaaaaggc aattccagtt ctgaaaaaat
    45781 tagagaatgc aggatatgaa gcttattttg taggtggaag tgttcgtgat atcttgctga
    45841 accagccaat ccatgatgtg gatatcgcaa caagcgcatt tccagaagaa atcaaacagc
    45901 tttttccaaa aacgatagat attgggatcg aacatggaac tgtgttggta ttagaaaatg
    45961 atgaacaata tgagatcacc acatttcgga cggaatcaac ttatcaggac taccgtagac
    46021 cagatcatgt cgaattcgtt cgttcgttgg cagaagattt gaaaagaaga gattttacga
    46081 tcaatgcgtt tgctttgaaa gaagatggag aaatcatcga tttgttcgat ggtctgcaag
    46141 atctagaaga acagatcttg cgagctgtag gcaatcctca tgagcggttc catgaagatg
    46201 ccttacgaat gatgcgcggg ttgcgttttg tcagtcaact agggttcaaa ttagaggaag
    46261 aaaccttcta cgccatcaaa gaaaaccacg agctattagg taaaatatct gtagaacgta
    46321 taaatgtgga attcatcaag atgctcttgg gaaatgaacg ggccgcggga atccatgcat
    46381 ttattgaaac agagtgctac atttgctgtc ccggtttgaa agaagaaggc gaagcacttt
    46441 tacgttttgc tgaattacca tccgtcccat tgaaagaaga gagccaagca tgggcattat
    46501 tgatcagcca actggatcta aaagaaaatg agattcgttc ctttttgaaa tcgtggaagt
    46561 gttctaacca aatgattaaa gacgttcaag cacttgtcca aggactacga caacgagaaa
    46621 ctggagcttt ggaaccattc gaattgtact tcttaggcaa aaaacatgca ctgcaagtag
    46681 aagaattgat gatctatttt gacgaaacac ctcagatgga tgccgtagga gaatcctatg
    46741 atcgtttacc tatcaagtca ttaagcgaat tagcagtaga tggtaaaatc ttgctagaag
    46801 aaactggaaa aaaacctggt aagtgggtta gtgaagcttt gcaattagct gaaaaagccg
    46861 tcgtagaaca aagaataaaa aatgataaaa aacaggtttt ggatttttta tcgaaagaaa
    46921 aattgattta aaaaacacta gactgtatct gctcagcttt gttggctact taaagtgggc
    46981 agatacgtca ttagaagaaa aaacataaga tgtgaccact tacataaatt tgtgctaaac
    47041 tgaggtagta caagaataaa ttacatcata aaggagtctt tttaatgagt aaagaaatga
    47101 cagcgctaaa attttatttt agaaatggag aaacctggac gatcaaccgc cgtcatatcg
    47161 gcgatctttg gatcaaacaa atcacaacaa gttttggacg aatcaatggc agtgaatttg
    47221 ttgaaatcca tccgtgtgct ggatttaaaa tcgaaatctt ccatgaaggg gacgcagttg
    47281 cgacacatga tatcaaccta ggcggactgg aaatgggcat gtttaatcgc gcattgaaat
    47341 acgaagatat cgagcgaatg gaaatccttt accgaaatgg cacacctgat cttgtgtact
    47401 tcccatatct agataaagga acagaaggat tagacaatca atatcaatca acaaaaatca
    47461 gcgaaaaaac aggtaacttg tatatcgtga tcaatccaga tcaacgtgta gaagatgtat
    47521 acggggaatt tttcgaataa atcgattttt acgcaaaaat gaggctgtga aagagatgtg
    47581 tcttattact actgataggc tgtctcttcc acaccgttta ttcagaataa gggactgtga
    47641 caagattttt gtcgcagccc catttttttg ttgtgataaa agaacaagaa aggcaggaat
    47701 gggaaagtaa acatcctttt gtcagaaact tttatctttc ttaagtttta cttgatatct
    47761 gatactattt ggaatagaat gaggcgttga aaaatttatg gaaatttcta actagcaata
    47821 aacgatgaaa caatgaaata tttttcatcc aaaaagaact ttgctataat gatggaagtt
    47881 tgtgtatagg agatctggaa aatgagagag agttttgaac aacaaaaaaa actgttgcat
    47941 gatcgctatg gcgccctttc gatggatgac cgccgtcaaa tactttgtaa gttgcgtaaa
    48001 agaaatatat tgatgtatcg tcagttggaa cgtctgaaac atgatctgct tcgtttggag
    48061 tcaaaacgtg tacagtgtga attagagggg aaccaaacac aggttgaagt agtcgaaacc
    48121 aaaattttaa agaaaaaaga acaattttta aaaatgctta cacaaaataa aaaataaagg
    48181 ggatggacga tggaatttgc tgagttagtt attgtatttg cagtaacgat caccttatcg
    48241 aacatagcta gccgcatttt gccaatgatt ccagctccac tgatccaaat tttccttgga
    48301 gtggtattag gtctgacaga gtggggacaa tcaatcgatt ttgaacctga attgttctta
    48361 gttatgatta ttgcaccatt gttatttaga gaaggagaaa aagcagatat ttcttcgatt
    48421 ctcaaaaatt tcgggacaat tttgttcttg gcatttggag gagtcatttt gacccttgtc
    48481 ggggtaggtg cgacgttatc attcctgttg ccaagtgtcc cacttgctgc ctgctttgct
    48541 tttggagcag cgttaggtcc gacagatgcg gtagcagtca gttctctttc tggacgagtg
    48601 aatatcccta aaaaggcgat gcatattttg gaaggagaag gtcttttgaa tgatgcatct
    48661 ggtgttactg ccttccagtt tgctcttggt gcgctgatca ccggatcttt ttcagcagta
    48721 aacgcgggga tgagtctagt agtttctagt attgggggag ctttgatcgg ctttttgctt
    48781 gtctggttca aacaaaaaat aattcatttg atcgaaaaag catcagcaca agatgtcaca
    48841 gggtatctgc tgatcgaact tttgcttcct tttctagcct atgtattggc agaggcattt
    48901 gatgtatctg gaatcattgc tgcagtggca gcaggtattc tccaagcttc tggttttagg
    48961 aaaatctctg tgtttgatgc agaattgtcg agcttgtccc acagtacatg gacaactatt
    49021 gcttttacac tgaatgcatt agtatttata tttttaggaa tcgaattgac gcaagtgttc
    49081 tcgccagtat ggggagacgg tttatatcca aacggtcttt tattagcgat tatcgtatta
    49141 atctctgtca tgctttttgt gatcagattc atttctatca gtctttttta tgtattcaaa
    49201 gatggcagta aaaagttcaa aaaacagttg aacgagatct tgatcttaac atttggcggt
    49261 gtaaagggaa cagtcagttt ggctacgatt tttattttgc cattttcaat caataatatg
    49321 atgttttacc agcggtcttt gcttttgttt ctgacggcgg gtgtcatctt agtgactttg
    49381 gtcataggga tcattgtctt gcctatgctg acggaaacag aggaagcgaa aagcacggat
    49441 ttgaatgctt tgatgatttt agaagaggtc gttgaagttt tgcgaaaaga aataaaggaa
    49501 attgatcgta atacaaaaga atttttagcc actgaagcag tgatagaaaa ttatcaagaa
    49561 cggatacgtg atctgtactt ggaagattta accgatgatg aaaagcaaga agtacaagaa
    49621 atacaagcac tgattttgtc gatcgaacgg gatggattgg atgaaagtta tcgttcgggc
    49681 aagctttctt ctaatggtta tcgtttttac tcccgttttc tttctcgatt cgaacattct
    49741 atcacaagcc agattttgtc ttttatcggc ttttggttca ttgttgtccg taggttaatg
    49801 cgaatcgttc tccatccgaa aatgttttgg caaagaagat atgctgatcg tcagacattt
    49861 attagtgatg aagatatcca agaaatcaga gagacatatc aaaaaaatac tcagttgatt
    49921 attgaaagtt tagataactt gactgatatt tatgatgaaa cgatggttca attttttatc
    49981 cagcaacgca aacttgaagg aataaaaatg aactcgggga atttgatttc ttcgtggatg
    50041 atccagcaag atagtctgtt tacgaaaaaa atgctaagag gttattatct tgaaagaaaa
    50101 atcattgatg aatacgaagt tgctgaaaaa atcacgacgt tttctgcgaa cagctatcgc
    50161 aggaatatca atttgttaga atcttatacg atgaacaaac catctgataa cttttctttc
    50221 cgatttgcgt ttcgagcaaa gtcaaaaaaa acgagtccaa taaaataaaa aggtaaaaat
    50281 tttcaagttt tataaaaaac aaaacatatc agaacaggat cgaatcggtc ctgttctttt
    50341 tttgagaaca caaaaagaac aaataccaaa aaaattttcc tgaagttcac tatttttatg
    50401 atacaatatc caagataagg agggaacatg ttgaaagaat taaaagtaac tgacctcaaa
    50461 aaaacttatg gtgaaaaaga tttgtttgac cagatttctt ttttggtcca cgaaaaagac
    50521 cgtatcgggt tgattgggac gaacgggacg ggtaaaacaa gtctcttaaa tattattgcc
    50581 ggtatcgata gcagcgacgg tgatcggcaa acagtgtttt atccaactga ttaccgtatt
    50641 ggttatcttt ctcaagcagc tgaattttcc gatgaattaa ctgttctcca agcagtcttt
    50701 caaggaaaca gccccttgat ccaaactgtt cgagcatatg aggaagcatt gatcgaacta
    50761 ggggaaaacg gagaagaccc tgatgtgcaa aaacgttatg ctaaagcaga agaacaaatg
    50821 aataaagaag atgcttggac tacagatacc aacgcaaaga ttattttgca aaaattagga
    50881 atcagtgaat tagataaaaa aatcagtact ttatcaggtg gtcagaaaaa acgagttagt
    50941 ctggcgcaag tgttgattga tgaacccgat ttactattac tagacgaacc aacaaaccat
    51001 ttagattatg aagcgatcga gtggttggaa aactatttga aacaataccg tggcgcacta
    51061 ttgatggtta cccacgatcg ttattttcta gatagagtag caaaccgaat cttcgaactt
    51121 tcatttggaa aattatacga gtataaagga aattatgaag cttacgtctt agaaaaagca
    51181 gaacgtgatc gtgtagaagt agaacaagaa gaaaagcgca agcggcttta taaacaggaa
    51241 ttagcttgga tgagggctgg cgtacaggca cgtggcacca agcagcaagc acggatcaac
    51301 cgtttcgaag atctaaagga gaacttgtac caagtaaacc aagaagatga tttagagctg
    51361 aacctagcga cacaacgttt agggaaaaaa gtactggaaa tcaaagatgg cagttaccgt
    51421 ataaatgacc aaacactgct agaacattta gatttattga ttcaatctcg ggaaagacta
    51481 ggtattactg gtaaaaatgg tgcgggaaaa tcgacattgc ttaatattct agctggcaga
    51541 attcccctgg atagcggtac aatgtctatc ggtgaaacgg ttcatcttgc gtattataca
    51601 caagaaaatg aagaaatggc accagataaa cggatgattg cttacttaca agaagctgct
    51661 gaagaagcaa aaacagcaga tggcagtcaa atcggagtag cagaattact tgaacgattt
    51721 ttatttccaa gatttatgca tgggacactg ataggcaaac tttcaggcgg agaaaaacgc
    51781 cggttatttt tgttgaaact gctgattcag caacctaatg ttttattatt ggatgaaccg
    51841 accaatgatt tggacatagc aacattgacg attttggaag attattttag aagttttcca
    51901 ggtgctgtga tcactgtttc ccatgaccgt tatttcttgg acaaggtagc agataagtta
    51961 ttagtattcc aaggaaacgg aaaacaagaa ctttattacg gaaacatgtc cagttattta
    52021 ctgaagcaaa aagagaccca gcagcctgct gaaaaagcga aaccaaaaat acagagcaag
    52081 gaacctgctg aaaagaagaa attatcttac atggaacaaa aagaatggga aacgattgaa
    52141 gatgagattg cagaacttga agaaaaaatc tcattgctcc aagaagagat gaatcatcaa
    52201 ggagataatt tcactcgatt acaagaattg caaaacgacg tatctgaaac agaagcacaa
    52261 cttgaagaaa aaatggcacg gtgggaatac ttgagtgaat gggtagaaga ttaggaggaa
    52321 aaaggatgga acaagcgtat cttgacttag gaagaaaatt gttggaagaa gggcatcgta
    52381 aagaagacag aacaggcaca ggcacattaa gcttattcgg ataccaaatg cggtttgatc
    52441 tgcaaaaagg gtttcctttg ttaacaacga aacgagtacc ttttggattg atcaaaagcg
    52501 aattgctttg gtttttaaaa ggagatacga atatccgcta tctattacaa aataaaaacc
    52561 atatttggga tgaatgggca tttgaacgct acatcaaaag tccagactat aatggaccag
    52621 atatgactga ttttggccat agatgtttga cagatcctga attcaatgaa gaatataaaa
    52681 agcagagcaa gcttttttgc gagaagatcc taaccgatga ttcctttgct gaaacatacg
    52741 gcgatcttgg acacatctac ggctatcaat ggcgtcactg ggaaacaaaa gacggtggct
    52801 ttatcgatca aatcaaacaa gtgatcgaag caatcaaaaa gactcctgat tctagaagat
    52861 tgatcgtttc tgcatggaat ccggaagatg ttcctagcat ggctttgcct ccttgtcata
    52921 cgatgtttca attttatgtt caagagggac ggctaagctg ccaattgtat caacgcagtg
    52981 gggatgtgtt tctaggcgtt ccgttcaaca ttgcaagtta tgcgttgctg actcacctaa
    53041 ttgcacatga aacaggttta gcggttggcg aatttgttca cacattagga gatgctcatc
    53101 tttatatcaa tcatatcgaa caaatgaaag aacaattgag ccgagaaata cgcgcatttc
    53161 cgactttagt tttgaatcag gaaaagcagt cagtatttga ttttgagatg gaagatatcc
    53221 aattagaagg atatgaccca catccggcga tcaaagctcc tatcgctgtt tagaatcaga
    53281 aaggatgaga aaatgttagc tgcaatttgg gcacaggatg aaaacggatt gattggaaaa
    53341 gaagaccgtc ttccttggcg tttgccaaat gatctgaaat tcttcaaaca aatgacagaa
    53401 gcaaatacac tagtgatggg acgaaaaaca ttcgaaggga tgggtagccg tccgttgccg
    53461 aatcgtcaga cgattgtttt gacgagagat tcttcctata aagcagaagg cgtgcatgtc
    53521 atgcatagtg tggaagacgt gcttgctctg gaaaaagaaa cagacggtat ctttttcatc
    53581 gctggagggt cagctgttta tcaagaattt ctgccatttt gtacgatatt ataccgtaca
    53641 gtcatccatc atgtattcga tggagatgct tattttccac ctgttgactg gtctgattgg
    53701 tcactgatca atactagtca aggagaaatg gatgaaaaaa atcgttatcc gcatcaattt
    53761 gaaacgtatc agcgtaatga gaatcctgta aaaagcggga caggcgaatt gacgatataa
    53821 aaaagctatg gatagactag ctgttattta gagctgtccc atccatagct ttattttttt
    53881 tattaagtaa agaataaaac agagaagtac ataaaacctg cacctaacat aacaaacaaa
    53941 tgccaaacaa catgcatata gcggatagaa ttcaagctat aaaagaatgc gcctatcgtg
    54001 taagaaagcc cgcctgctac catcaaaata acaccagtca ttccaagaga gtgataaaga
    54061 ggaacagcag ccacgacaca gagccacccc ataaaaatat agatgatcgt agatactttt
    54121 gatactctct cccgtttatg caacgtcaac gctttatata taatgccaag aatcgcaaac
    54181 aaccagatta atacaaataa agtccaacct agccatcctc ggatactcag caaacaaaaa
    54241 ggagtataac ttcctgcaat caaaagaaaa atcgaactat gatcgaatac ttggaacacc
    54301 ttttttgctt ttgtaaaaat caatgaatga aacaaagtag acgttaaaaa taaaagaatc
    54361 atcatcgatc catagatagc ataagagaca atatggaggg aggaatgcaa gtgggcacct
    54421 tttactaaaa gaaccactag tcccgcgata ctcaatccag tcccaattcc atgggtgact
    54481 gcattaaaca cttcatttaa tatttcatac gttcgattaa atttcgtttt ttccatgaaa
    54541 acggctcctt tactaggtgt aattaatgaa aaatcattat ttgtctgtta tactaaaaat
    54601 agaaattgtc ttacatgtag tttaacatga ataaggcatc ttgttaaaga aagagagaga
    54661 gaaaataatg acaaatgtaa aaatcgtaac agattcttca tgtacgatgg aaaaaaatgt
    54721 acgcgatgct ttaggcattc gtgtcatgcc gctatccatc atgatcgacg gaacagtata
    54781 tcccgatgat gaccaactag acggcgaaag atttatggaa atgatggcga aagcaaaaaa
    54841 tctgcccaaa acaagccaac caccaattgg agaattcatc tcgatgtatg atgagctagg
    54901 agaagacggc agtgaagtga tttcgatcca tatgacaaaa ggcttgagtg gaacagtaga
    54961 agcagcaaga caagccagta atctaacaaa aacgaaagta acggttatcg acagtgatac
    55021 cactgaccaa ggattatctt ttcaggtaat tcgagcagct gaattagcaa aagaaggtaa
    55081 aacagtagag aaaatccttg aagaagtcaa aaaagtacaa gacaatacaa aattatacat
    55141 cggaatatcc acactagata acttggtaaa aggtggaaga atcagccgaa caactggttt
    55201 gctgtctagt gttttgaaca tacgcgtggt gatgaatttc gcccattctg aattaatccc
    55261 tgtaactaag gggcgaggaa agaaaacgtt cgataaatgg tttaataatt tgaaaaatga
    55321 actgaaagaa ttgccaaatg tgcgacaaat cggtatttca catgcggatg caaaagaatt
    55381 ggcgcaagaa ttcaaagagg gtttgcaaga attattcccg gacatgcata tccctgtact
    55441 gcatacgaat ccggttatcg ctacgcatac tggtaaagac gcgtttgcaa tcatgtatta
    55501 tgtagattag tcgaaaagag gataagccct cagcctgaaa ggcttgcagc ttattctctt
    55561 tttctttata aaattaggaa aataattgtt ttcttttttc ataaagacta cctttttgat
    55621 aaaatttttg ataacattag aaccaatcga atacaagagg tgaaaaaatg aaattaacga
    55681 aacgacattt gatcctcgtt ttgttcccat tattaattgc gatcatcatc tatgcaggtt
    55741 tagctgcttc tataccgaaa gctggcccac taatgaaacc agtaactact gtgagagaag
    55801 atccaaataa aaaagaaaaa cttcactaca tagctatcgg agattcgctg actgaaggag
    55861 taggagatca aaccaagcaa ggaggattcg ttccccttgt cgcaaatgat ctaaaagacc
    55921 gttataattt gaccgcggtt gaaacagaaa actatggtgt aaatggtgaa cgaagtgacc
    55981 agatcttaaa gcgagtaaaa acaaaagaag aaattcgaaa caatatcaaa acagctgatt
    56041 ttatcacact gactgttggc ggtaatgatt tgatgaaagt tatccaaaat aatttattcg
    56101 ggttaacggt caattccttt aaaaagccac tgaaaaacta tcaggaaaat gtcacagaac
    56161 tattggaaga atttcgatcc ctcaataaaa ccgcacctat ttacatttta ggcatctaca
    56221 atccatttta tttgaacttt cctgagatca ctgacatgca gacaattgtt aacaattgga
    56281 acaaaggaac agaaacggtg acaaaaaaaa tgccgaactg ctactttatc ccaatcaatg
    56341 atttgcttta tcaaggattg aatcaggaag taggtgtcac agaagaagga acagatcaaa
    56401 caactagcac gacagaaaat ctaaatggca tcaaaaataa tgtgctctat gaagaagatc
    56461 atttccatcc aaataattta ggttatcaat tgatggcaaa tgcagtgaga gatcagctga
    56521 tcgagacaca aaaccaatgg ttagagaagg aggatgatca ataaacatga aaacaagatc
    56581 tgacgtatct tcaaacaaaa caaagaaaac aaattactgg aaattcgcct tccttatcct
    56641 tcttggggta gtacttggtt cgaccgtatt tttaggcagc cgtatttttg ctaatcggga
    56701 accagaactc ccagaaatac cagctcttac ggaaagacaa ggagatcctg tcttaacgat
    56761 caattcaaat aaagaaaaag tcaatcaaat catcagcttt ttccttagtg agtatcaaaa
    56821 agatagtgat attgaatata aattttattt ggaaaatgaa gcactactca atggtacttt
    56881 cgaagtacta ggttttccta tcgatttcta tttatatttt gatccgtatg tgatggaaaa
    56941 cggaaatgtc caactaaaag ctagaagtct ttctatcgga acattgagtt tgccaatcaa
    57001 agatgtgatg aatatgatca agagaaacta taaattacca gattggatcg aagtcaatac
    57061 agatgatctg actatcatgc ttaggttgga tcaattccga atgcaaaacg ggatgtatat
    57121 taaagcagat aaaatcgact tagtaaatga tgacattcgg tttagtctat atttgccaaa
    57181 agatacctct gatgcttcaa acaactcaaa taccaacaaa actagcacca gcagtactga
    57241 aagcaagaca aaagaaaata aaaaatcatc ggatgagtag tattagaggg ggaatcataa
    57301 tggaacgagc aatatttgca ggaggctgct tctggtgtat gatccagcct ttcgacacgc
    57361 ttcctggtat ccatacagtg atgtcaggat atactggagg gcatgtacca gatccgactt
    57421 atgaacaagt aaaaagccaa acgactggac atacagaagc agtggagatt atctatgatc
    57481 caacattgat ttcatatgaa caattagtag aactttactg gcagcaaact gatccaactg
    57541 acgctttcgg acaattcgag gatcgcggtg acaattatcg cccggtgatc ttttatttga
    57601 cagaagaaca gcggatcatt gctgaaaaaa gtaagaaaca gttagctgaa agtggacgtt
    57661 tcgaacagcc aatcgttaca aaaatcgaac cagcccaacc attttatcta gcagaagaag
    57721 accatcaaga gtattataaa aagcatcctg aaaattttaa aagaaaccat gcacgccggg
    57781 ctgcctttat cgaagaaaat tggaggaacg aagggtgaat cgaagctttt ttcattattt
    57841 aatgacactg cgaggcggtg gcacacatga tgctttatct gttttcgcta cagaagccgg
    57901 taaagacatc caatttccta agcacagctc tagctacgaa gaaatttcta attatctgga
    57961 actgaatgtc gactatttgc cgtccatgga tatctttgac gaagcatggg aaaaatattt
    58021 agaaaataat catgacatat aagagatagt tttgtacttt atgatcaaaa aagttttttg
    58081 tccaatagcc taattgaaag aattattttt atttcagcta tctagtcgca tttttttgat
    58141 atttttctta taataaagaa agaatgaaaa aaagagggat ggattgatag agattgacaa
    58201 aaaaacaacg ctatattaat cgcttctggc ttgtattcaa atacttactt gtttctgtat
    58261 tccttgcgtt catgttgcgg ggatttttat tcatcccggt accagtggaa ggcaattcaa
    58321 tggaaaacgt gttgaagcaa ggtgatatgg ttgtgatgga aaaattttcg gagatcagac
    58381 gatttgatat tgttgttttt caattagcag atggcacgat ttatatcaaa cgagtaatcg
    58441 gtcttccagg agaaaatgtc agctaccaaa atgatcaatt gaagatcaat gggaaagtag
    58501 ttaaggaacc ttatctaact aaaaacctga aatcagatca tgcaaatgca tcctatacga
    58561 cggactttac actacaagag ctaacgggac aatccaagct tccggaagat aattattttg
    58621 tacttggaga taatcgaaga gtttcaaaag atagtcgttc gtttggcacg atcaataaaa
    58681 ctgatattct aggtaaagca agatttgtct attatccact tgatgaaata aaatggatcc
    58741 agtgagaaac aataaagcgt gcagtctgtt gagactgcac gctttattgt ttaatccaaa
    58801 atcagtttac taccttagta cgtaaaatca aacagctcgt ttaaacactt ttctagcctc
    58861 taaagttttg ataaatgaat aaacaaccat tatttgaata gggatttgga tcatattcct
    58921 gatgaatcta cctagaaaaa ttactttgaa atctgcacca aacaaaacag acatcagcca
    58981 agaattgata aaaaggctga ctgggatcat aatcaataat tgggcagcga tgacggaagg
    59041 caggtttatc tttttatgat ataaaaataa gccattaata aatccaccaa ggaaagccgt
    59101 gataagaaaa gcagcttgaa acgttcctga accaaatatc gtgaaattta aagtgttcga
    59161 caacatttca agcaaaccag cccagatcgg tccatataga taacccataa gcgccatact
    59221 taaaaatccg aatgtgattt gaaaataagc aggaccaatc gctatcttgt ataagatgac
    59281 atcaagggct aataaaagag cagaggtcga caacaatctt gcattcattt cgggcaatct
    59341 aaaaacgtct tttgcaatca aagtgttcaa aatattctct cctttgtcag ttaataataa
    59401 aaggatacca taaaatcacc aatgtgtcat gacacattgg tgatttacat acactggcat
    59461 ctaacaatta aaaaaagggt gagaagactg cttttataaa ctgtaaaaaa gagattgtac
    59521 gaataaaaaa aatagaggcg gagaatactt atcgtatcat ccgcctttgt ttttttgtta
    59581 taaaaaacgt cagattagtt atctgcttac atcttcatcc atacgggttc taatgtattt
    59641 ccgtctagat cttggacttc taatgaaaac atttcttctt caggcattcc catatctact
    59701 tcgtggaaag taccaccatt ttcttttgca atttgagcaa atttttttac ttcatccgca
    59761 ttttcaacac taaacgaaat caaagcacca cttgtttttt tattatcagc tatttcttta
    59821 tcttttataa attttttata aaaatcatga gagagaagca ttatccaaaa agtgtcatcc
    59881 cataccattg aaccagcttc ttcagtagaa aattcttcat tttttttaaa acccagcttt
    59941 tcataaaaag caacggaacg attgacatca gcaacaggaa aattaacaaa aaccatacta
    60001 ttcatttgtt tcgtctcctt tctgttttgt tcgtctatca tctcttattt aggaaacgct
    60061 gtcaaaaatt tagattcata tatagaaacc aaaataaaaa tttgcatcat caaaaaagtg
    60121 aagatgtgat agaatgagga ctggttcact ttcacttaac taatagatgg aatttcttta
    60181 taataaaaaa gtgaatttat attgaaaaag aaaaaaacaa gtaaagccgg ggaatattcc
    60241 ggtatgaaag gaatggagag aacaatgacc atccaatggt ttccgggaca tatggcaaaa
    60301 gcccgacgag aagtttctga aaaaatgaaa tatgtggaca tcgtatttga attggtagac
    60361 gcacgattac ctttatcttc tcgtaatcca atgctagatc agatcattca gcaaaaacct
    60421 cgccttgttt tattgaataa agcggatctg gcagatccac aacagacaaa gctgtggcaa
    60481 gaatattttc gtaaacaagg ccatcttgca ttagctatca cggcacaaga aagtaaagga
    60541 attaaaggtc tagtacctgc ggctaaagaa gcattgaaag aaaaacgggc aagagatgct
    60601 gctcggggga tcaagcctcg cgctattcgg gcaatggtct taggtattcc aaatgttggg
    60661 aaatctacgt tgatgaatcg actagtaggc aagaaaattg cacagacagg aaataagcct
    60721 ggcgtaacaa aaggtcagca gtggcttcgt ttaggtaatg agttggaatt gttagacaca
    60781 ccagggattt tatggcccaa atttgaagat gaagaaatcg gcaaaaaact agcgctgaca
    60841 ggcgcgatca aagaccagct tgtccattta gatgatttag cgatttacgg attagacttt
    60901 tttgcccgat attattcagg aagaatcagc gatcgttatg gtttatcaat cgagcaagaa
    60961 gaaaaattgg caccggaatt actgatggat attacagcaa aacgtgggta taaagaagac
    61021 tatgatcgtg gcagcgaatt agtcgtgcat gatattcgtc aaggaaaact tggacgatac
    61081 acactggatc gttgcgaaga aatggagcaa aaaagtgatg actgaatcca tccaaagtat
    61141 caaagaacga ttgaaaagca tacagagaat agatgatcct acactagaat cattaagaaa
    61201 tgatccacgc aaaggcgtgc agcaagcact ggcttctttt gaacgacgat tgaaaaagga
    61261 agcattaatt aaggaaaaat atgaagaaat gttttgcttt gaaaagcaag ggtacgcaca
    61321 aggtcaccaa tggattgccg gcattgatga agtaggaaga ggaccattag ctggacctgt
    61381 cgtggcagct gcagttatct tgccgaaaaa tgagatcata ttagggctga atgactccaa
    61441 acaattatca gagaaaaagc gagaacttct ttatcaacaa gttcaagaaa aagccctggc
    61501 aatcgggatc gggatcgttg atcagcagac aatcgatgat gtgaatattt atgaagcaag
    61561 taaattagcg atgatccaag cagtagaaaa attgtccatt gtaccaagct atttgttgat
    61621 cgatgcgatg accttggatt tgcctattca gcaggaaaaa ataatcaaag gggatgcacg
    61681 atctgtgtcg attgctgctg caagtatcat tgctaaagta tatcgagacc aattgatgaa
    61741 agaatatgac gtgctttatc ctggatatgg tttctcgcat aatgcaggtt atggaacaaa
    61801 ggaacactta gaaggacttg aacgacaagg aattacgcca atccatcgta aaagttttgc
    61861 acctgtaaaa aaatatttac aataaaaaac agccgctttt acgtatctta ttagaaagag
    61921 agacgaaagg cggttttatg atgtatcaaa tagaagaaaa tttattgaaa cttgcttata
    61981 caaaaggaat cagtagtcaa ggaaaatggg cacttgctaa ctggatgatg cagtatcctt
    62041 ataaagaaat cggatttgaa gacatcatta agataggtaa aataaccaaa caccgggagc
    62101 tgtttcgcaa aagttggcag gaaattcacg ctaactgggg caaaatccaa tcgaaacagt
    62161 cgtttatcac ttgctttgat cccaaatatc cccctcagct gcttcacttg acctatccgc
    62221 caattgtact gttttataat ggtgatctat ctttactttc ttgtaacatg ttaagcgttg
    62281 ttggtggaag acacacttct gctttagcca aaaaaacagt ttattattta ctaaaaccag
    62341 tgatagaagc tggatatgtg atcgtcagtg gctgcgcgaa agggatagat acatacggtc
    62401 accaagcagc aatctctcat ggtggacgga caatcgcagt cattggaaca gggatagagc
    62461 aagtctatcc tgctgaaaat cgtgacttgc aagaggtgat tgcaaatgat catcttcttt
    62521 tgagtgaata tcctcctcaa tccggcccga aaaagcattg ttttccaatg agaaatcgga
    62581 ttatcgcagc tttgtctaaa ggaacatgtg tctttgaagc caagaaaaaa agcggctctc
    62641 tgataacagc acagcaagca ttggatcttg gaagaacagt tttttctgtt ccaggaaata
    62701 ttttaacaga acattctacc ggatgtcatc atttgatcca agacggtgca gtttgcacgg
    62761 tttcgggtga agatatcttg gcagaattta aagaataaca ccatactttt catttgcttt
    62821 tcttgacaaa cgttttctga atggatatga ttagctacga tttgtatgaa tcctctttta
    62881 atagtaggaa cacgacaatg gaaaggagtc cattcagtaa tggcgtataa atatttagtg
    62941 attgtagaat cacctgcaaa agccaagaca attgagaaat atcttggacg aaactataaa
    63001 gtaatggcca gtgttggcca tataagagat ttaccgaaaa gtaaaatggg tatcgatttt
    63061 gaaaacaatt atgaacccca ttatatttct atacgcggaa aaggcgatgt catcaaaagc
    63121 ctgaaagccg cagcaaaaaa agctcaaaaa gtttacttgg caagtgaccc ggatagagaa
    63181 ggagaagcga ttgcttggca tttagcgtac ctacttgggt tggatctgaa agaaaaaaat
    63241 cgggtggtct tcaatgaaat cacaaaagac gcagtcaaag cagcttttaa ggaaccaaga
    63301 acgatcgatg tagatttagt agatgcacag caagctcgtc gtaccttaga cagaatcgtt
    63361 ggttattcga tcagtcctat tctctggcgt aaggtcaaga aagggttaag tgcaggacgt
    63421 gtccaatctg tcgctttaaa aattattatt gaccgtgaaa aagagatccg agaatttgtt
    63481 ccagaagaat attggagcat cgacggtaat tttaaaaaag ctcgcaagaa attcaaagca
    63541 aatttctggg gaatcgacgg taagaaaaag aaattaccag atgcacaaag tgtaaaagaa
    63601 gtcactgcta gaattgatgg aacagacttc gaagttaaaa aagtagaaaa gaaagagcgc
    63661 aaaagaaacc ctgcgaatcc tttcactaca agtagcctgc aacaagaagc tgcccgtaag
    63721 ttaaactttc gaacaagaaa aaccatgatg gtagcacagc aattatatga aggaatcact
    63781 ttgggtaaac aaggaacagt cggcttgatt acatacatgc gtactgattc tacccggatt
    63841 gccgatacag caaaagcaga ggccgcagca tttattgaag atacgtatgg aaaagaattt
    63901 tctagacatg atcaccgaaa gatcaaaaat gctcaaggcg cacaagatgc ccatgaagct
    63961 gtgcgtccaa cgagtgtgct tcgtacacca gatgaactca aacaatattt agataaagat
    64021 caattgaaac tttatacatt gatctggtca cgttttgtgg ctagtcagat gacaccagct
    64081 attttagata caatgaaagt gacattagaa caaaatggtg tcatcttcat tgcgaacggt
    64141 tcaaaaatca aattcaaagg attcatgcaa gtgtatgtgg aaggtagaga tgacggcaaa
    64201 gaagagaaag aaaatattct tccagaactt gaagaaggcg atgtagtcca atctgttgat
    64261 attgaaccaa aacaacattt tactcaacca ccagcacgtt ttagtgaggc tacgttgatt
    64321 cgtgcactag aagaaaacgg ggtagggcga ccttccactt atgcaccaac acttgatacg
    64381 atccaaagac gctactatgt aaaattgaca caaaaaagat ttgagccgac tgaactagga
    64441 gaaattgtca attcattaat ctgtgaattc ttccctcaaa tcgtcgatat ccatttcaca
    64501 gcagaaatgg aaggagattt ggataaaatt gaagaaggca cggaagcgtg ggtcaaagtg
    64561 gttgatcgtt tctataaacc gtttgaaaaa gaactgacga atgcggaaga aaaaatcgaa
    64621 aaaattcaaa tcaaagatga accagcagga ttcgattgtg atgtctgtgg acatccgatg
    64681 gtgataaaat tagggaaata tgggaagttt tatgcttgca gtaattttcc tgattgtcgg
    64741 aatacgaaac caatcgtaaa agaaatcggt gtgacttgcc cagtatgtca tgaaggacaa
    64801 gtcattgaac gaaaatctaa gaaaaacaga ctattctatg gttgttcccg tttcccagaa
    64861 tgtgaattca cttcttggga taaaccagtg ggcagaaatt gtccaaaatg tgacggatat
    64921 ctggtcgaga agaaagtcaa aggcggtaaa caagtagtct gtgtaaatgg agattacgaa
    64981 gaagacatcc aaaaataata gaaaagaggt tctttcattg aaaatggtaa atgttgttgg
    65041 agcagggctt gccggaagtg aagctgcttg gcagatcgca caagcaggag tccctgtccg
    65101 tttatatgaa atgcgtccag tcaaatcgac tgaggcgcat cacacaagta attttgctga
    65161 actagtatgt tccaattcat taagaggaaa cagtttggct aatgcagtag ggttattgaa
    65221 agaagaaatg cgccgattga attcggtagt aatcacttcg gcagatgaaa cagcagtgcc
    65281 agctggtggt gccttagctg ttgaccgcga ttctttttct gaaacaatta cccgaaaagt
    65341 caaagagcat ccattagtaa cagtgataaa cgaagaaatt actgaaatac cggaaggaat
    65401 caccgtagta gcaacaggac ctttgacttc tcatccatta gcagaaagca tcaaagcatt
    65461 caatggttca gatggttttt atttctatga tgcagctgca ccaatcgtag acaaagctac
    65521 gatcgatatg gataaagtat atttgaagtc ccgctatgac aaaggagaag cagcttactt
    65581 gaactgtccg atgacagaag aggaattcaa agctttccat gaggcactaa tcaatgccga
    65641 agtggcagaa cttaaatctt ttgagaaaga aaaatatttt gaaggatgta tgccaattga
    65701 agtaatggca cagcgaggat tcaaaacgat gcttttcgga cctatgaaac cagttggatt
    65761 ggaagatcct aaaactggca aacgtcctta tgctgttatc cagctgcgtc aagacaatgc
    65821 tgcagcttct ttatacaaca tcgtgggctt tcagactcac ttgaaatggg gcgagcaaaa
    65881 acgtgttttc cggatgattc ctgggttaga aaatgctgaa ttcgttcgct atggtgtgat
    65941 gcaccgaaac agctttatga attcgccaga attgctgaaa ccgacttacc aatcaacgaa
    66001 acgcgaagat ctgttctttg caggtcagat gactggtgta gaaggctatg ttgaaagtgc
    66061 agcgagcgga ctacttgctg gaatcaacgc cgcacgctta gcaaaagaaa tggaaccagt
    66121 cgagtttcca caagaaacag ctattggaag tatggcttac tacattactc atgcggaagg
    66181 aaaacatttc caaccgatga atgccaacta tggtctgttt cctgaactgc cagagcgcat
    66241 tcgagacaaa aaagcaagat atgaagcaat tgcacaacga gctttaaaag ctaatgaggc
    66301 aataaaaaca gaattagaaa aaactgcaat cccaaatgag taaggaaact ccatgaagag
    66361 ggtgagacgg atagtctcgc tctttttctt gcgtttttct taagaatttc tcaaacaaaa
    66421 tgtgaggaat tgcgccaatt gtgaacaaac ttagaaatat tggttaaatt ctgacaattt
    66481 atttgtcttt ttataaacgc tgtgctaaat tattctctgg gacaaaagga aggtgagaaa
    66541 atgacagaag ccacgtggga acaaaaattt ttgcgttatt tgattgtcga aagaggatat
    66601 tcagaaaaaa cgaaagaagc atatgaagaa gacattctcc atttcaaaca ttttttggag
    66661 gaatctggag acgctgatct gctgaaggcg gaatatttta cggttcgtgt ctatttgagt
    66721 gcattagctg atcatcgtcc tagctatagc agaaattcta tcagtcgcaa gatagccagc
    66781 ctacgttcgt tttatcagta tcttctcaaa gaagaagtga taaaagaaaa tccattttct
    66841 tacgttcatc tcaaaaagaa aaatttgaga ctgccacgtt ttttttatga aaatgaaatg
    66901 caagcacttt ttgacagcgt agcaggagat agtcctttgg atttgaggaa ccgcgcttta
    66961 ctggaagtcc tttacgggtc aggcatccgt ttaagtgagt gtagcagttt gtcggtatca
    67021 gacattgatt ttgattcaga ggtcatgttg atccatggta aagggaacaa agagagatat
    67081 gctcctctag gttcttttgc tcaagatgct ctgcaagaat atttcaggga aggccgccag
    67141 gtattgatga caaaatatca cgaagagcat gatatcgttt ttgtgaatca tcatggaaaa
    67201 ccaatcacgc ctactggaat tgaatatgtc ttgaatcaaa tgatcaaaaa aagcagtttg
    67261 gatagtgata tccatcctca catgctgcgc catacatttg ctactcattt attaaataat
    67321 ggggcagatt tgcggacagt ccaagaattg ctaggacatg ccaatttatc gactacccag
    67381 atctatgccc atgtaacaaa agaaagttta caaaaaaact atcgttcttt ccatccaaga
    67441 gcgtaaaaat aaggaaaaga acaaatttag gaggaaacaa acatggtcga atcaccattt
    67501 cattcaacca ctatctgtgc cgtcgaaaaa gacgggaaat ttgctatggc tggagatggc
    67561 caagtaacaa tgggtgaatc tgttgtcatg aaaggcactg caaagaaagt acgacgtatc
    67621 tacaatggag aagttgttgt aggtttcgcc ggaagtgttg cagatgcgtt tactttagaa
    67681 gaaaaatttg aaggcaaact aaacgaatat aacgggaatc tacaacgcgc agctgtcgaa
    67741 ttagctcaag aatggcggac acagcaatct atgcaaaaac ttgaagcgat gctgatcgta
    67801 atgaatgata aagaaatgct tcttgtttca ggtacaggag aagttatcac accagatgat
    67861 ggtatcttag ctatcggatc aggagggaat tttgcgttgg ctgcagcccg agcaatgaaa
    67921 aactatgctc aaaacgacat gagtgcgaaa gaaattgcag aaaatgcgtt aaatattgcc
    67981 gcagatatct gtatctttac taatcataat attatcgtag aagaactgta agaggtgagt
    68041 agatatgtat gaattaaaac aaacaccaag acaaatcgta agtgaattag atgaatatat
    68101 cgtaggacag cacgcagcaa aaaaatctgt tgccgttgct ttgcgtaacc gctatcgccg
    68161 tttgcagtta gatgaaaaaa tgcaacaaga tattacacca aaaaatatgc tgatgatcgg
    68221 acctacaggg gtcggtaaaa cagaaatcgc acgacgtttg gcaaaaatcg tcaatgcacc
    68281 atttgtcaaa gtcgaagcaa caaaatttac tgaagtcggt tatgtcggaa gagatgtaga
    68341 atcaatggtt cgggatttag tagaaaatgc gatccaaatc gtagaaaaag agcagtacag
    68401 ccgtgtatac acaagtgcta aaaaaaatgc agaaaaacgt ttggtaaaaa tcttggtacc
    68461 tggtatcaaa aaagaacaga aacaatccac taatcaattt gaacaaatga tgaatctttt
    68521 taatgctagt cagcaaaata ccgctgaacc gcaagaagaa gtgacagaag atattcgaat
    68581 caatcgccgt acagtcttgg aacaactaca aaagggttta ctggatagtc gtgaagtaac
    68641 cattgaagtt gaagaccaaa agaaacctgc accaatgatg aacaatggat tggagcaaat
    68701 ggggatcgac ctaaatgaaa ctctaggtgc tttgacaccg aagaaaaaag tggaacggac
    68761 ggtaacagtc aaagaagctt tagagttatt gatcaaggaa gaatcagcaa aattagtcaa
    68821 ggatgctgat atccatagtg aggcaatcaa attagcggaa gaaagtggaa ttatttttat
    68881 cgatgaaatc gataagatca cttctaaatc acagcaatct ggagaagtat ccagagaagg
    68941 cgtccaaaga gacatattgc caattgtcga aggttcacaa gtaaacacaa aatacgggat
    69001 catccaaaca gatcacgtcc tattcattgc ttcaggagct ttccatttgt ctaaaccaag
    69061 tgatctaatt ccagaacttc aaggacgctt cccgatacgg gtagaattag atgatttgac
    69121 agctgaagat tttgtgaaga ttctgaccga accaaataat gctttagtaa aacaatacgt
    69181 cgcgttgatc ggtacagaaa atgtgtcagt tacgtttaca aaagaagcaa ttgaacggat
    69241 cgctcaaatc gctttcgatg tcaaccgtga cacagataat atcggcgcac gcagactgca
    69301 taccattttg gaaaaactac tagaagatct attatttgaa gcaccagata tgcaaatggg
    69361 agaaataacg atcacagaag catatgtgga tgacaaactt ggctcaattg cggcaaatga
    69421 agatttaagt cgctatattt tataaaaaat cggaggacga caatgacaga cttgctaacg
    69481 aaaacccgca agataaacac acttttgcag caaaagaata cttttgacat gcaagcagat
    69541 ttgccttacg ataaaatggc tgtcacacta ggtggtattc ttgacagcaa cacctatatc
    69601 ataggaagtg acggagtatt actaggttat aatgaacgtc acgatgtgaa caatgaacga
    69661 atcaaaacaa tgtttgttga gaaacaattt cctgaatctt atactgatac agtggcacag
    69721 ttgatgaaaa ctgaagctaa tatcccaatt actagtgata ttactgcatt tccggtagag
    69781 tcaagagaga aatatccatt tggtctgacg actgtcgttc cgatctttgg agctggcgaa
    69841 cgtttgggta cgattatctt atctcgtatg gaacaatcgt ttgcagatga cgatctagtc
    69901 ttagcagaat atggagctac ggttgtcggt atgcagatcc tttatcagaa gtctcgaagc
    69961 atcgaagcag atgtacggag tgcaacggct gtccaaatgg caatcaacac attatcttat
    70021 agcgaattga aggctgtaca agctatcttt gaagcattgg atggagatga aggtcgtctg
    70081 actgcttcta atattgccga tagtatcggc atcactcgtt ctgtgatcgt caatgcttta
    70141 cgaaaattgg aatcagctgg aatcattgaa tctcgttcgt taggcatgaa gggaacttat
    70201 ttaaaagtat tgaattcccg ttttaaagac gagttagcaa aacacagtta ttagaagtaa
    70261 ggggactggg gcagatagaa atgtttgttc cagccttccc attttaaaaa gtaagtcgaa
    70321 gttggaggaa tggcaatgac tgttattatt caaaatgacc agctgatcgc cgaaatcgct
    70381 gaacacggtg cggaattgat cagtctgaaa tcaaaagaac atggtttaga gtatatctgg
    70441 caaggtgatc cagcgtattg gggcagacat gcaccggttt tattcccttt tgttggacgt
    70501 ttaaaagatg atcagtatgt ttatcaaggg aaaacatatc aaatggggca acacggattt
    70561 gctcgggata tggattttga agtcattgaa catggacaag aaatggctag tttcatctta
    70621 aggagtacgc cggagacatt agaaaagtat ccatttgatt ttgaattagt gatcagctat
    70681 gaattaggag gagacggcat cacggttcat tatcaagtgg caaataccgg tgaaaaagaa
    70741 atgttctttt ctatcggtgg acatcctgct ttcaatgtac ctcttgaaga aggattgtca
    70801 tttgaagatt tctatctggc attttctcca ttgaaatcaa gattacgcct accattgaaa
    70861 ggcccattca tcgatatgga tcaaaagacg ttaggtcaga caaatacgaa tctggctttg
    70921 aatcgtgaac tttttgagca agatgccttg gtttttgaaa caaggggtct aaatgcgtac
    70981 gccattcgaa gtgaaaaatc ttcccatagc gtaactttaa gctataaaga tatgccttat
    71041 gtagggatct ggtctcctta tccaaaagaa gcgcctttcg tttgtatcga accgtggtgc
    71101 ggaatcgctg acacggtgaa cagtagtgga aacttgatgg aaaaagtagg gatcaatcaa
    71161 ctaggtgccc atgaaatctt caagacaaaa tattccatca cagtgaagta agaggttgtg
    71221 accgagaagt tagcagggaa caccgtttac caaggtgtgt aaaaaagcta tcctgtaagt
    71281 aataagggag tgtgacatcg atttgtcaca ctcccgtttt atctctttgg aatgaaaaag
    71341 tatcaggatt ttttcttgct gctattcaaa ccaaacggga ttcgactttc agtatggttt
    71401 ctgatacgct tgatattgtc tttatgccga taaaagataa aggaagaaac taaaaaggca
    71461 atgatcgtca gtaaccaatt gggcttagcc aaaatcacag gagctacata aggaaggacg
    71521 atcgtagata aagtgatcaa tactgcactg atcatactgc tcaaactcac catacttgta
    71581 caaaataaac taacgataaa gatgatacaa gaataaacaa aaaatacagg attaaatcct
    71641 aaaagcattc ctgcacttgt cgcaacagct tttcctcctt tgaacccagc aaaaatcgga
    71701 aatgtatggc caagaatggc gcatacccca aaccaaagag ggttaatccc agaaaggtgg
    71761 aagatcatcg gcaaacaagt agccaatgta ccttttaaaa tatccataag caggacaaca
    71821 atcccggctg ttttgcctaa tacacgaaat gtattggtcg ttccagtatt accgctcccg
    71881 tgttgtcgga tatctttttt gaaaaacaat ttgccaatcc agacaccgga aggaatagaa
    71941 cctaaaagat atgctaaaat aagtaataag atcaatttca ttttttaccc tctttcaagt
    72001 tgaaaactat cctttatttt agcatgaata ggtaacagga acaattgaaa aaatgaaaga
    72061 tacaagtata atagatggaa taaaaagaaa agcaaggggt ggcagaaatg tctgtaaaaa
    72121 atccaacaca agaaacgatt ttcaactatt tggaagaagc aaaaaatatt gccgtcgtag
    72181 gcttgagcaa taaaccagaa cgaacaagtt acatggttgc acaggtattg caagacaatg
    72241 gatataaaat cataccagta aatccattat tggctggtga agaaattcta ggcgagaaag
    72301 tctatgcgaa tttgacagaa atcgatgatc caatcgatat cgtagatgta tttagacgga
    72361 gtgaattttt acctgaaata gcaggtgatt ttttgaaaac tgatgctaaa gtgttctggg
    72421 cacaattagg gattgaaaac aaagaagcag ctgagatgct aagaaaagca ggacgtacag
    72481 atatcgtaat ggatcgttgt attaagattg aacttggtaa gttgaaagaa aaccaaaaat
    72541 aaaaatgacc acaaagaaga gatgatcgat agaggggaat gtcgaaaaag cggttaggag
    72601 ataattaaaa ttgatttctc gtctaccctc ttttttttca cgaccttttc tagtatgata
    72661 atcgtggtgc ggttttgccg caaagtatta ttgaaggagc gtttgccttg gcaaaaaaag
    72721 taaacaacga atacaatgac tcgtccatcc aagtattgga aggattagag gcagttagaa
    72781 aaagaccagg gatgtacatt ggatccactg acagccgagg cttgcatcat ttagtctatg
    72841 aaatcgtcga taatgcagtt gacgaagcat tatcaggtta tggcagtgag attgatgtga
    72901 ccatccatga agacaatagt ataactgttg cagatagcgg acgtgggatg cctgtaggaa
    72961 tgcatgcttc cggaatacca acagttgaag tgatttttac tgtgctgcat gctggcggaa
    73021 agtttggtca aggagggtac aaaacttctg gtggactgca cggtgtagga gccagtgtgg
    73081 taaatgcctt atcgaaatgg ctaattgtaa cgatcgttag agatggcgta gagtatcagc
    73141 agaaatttaa aaacggcggt aaacctgacg gtactttgaa aaagatagga aaaacaaaaa
    73201 aagcaaacgg gacgactgtc cattttttac cagatgatac aatattcagt acaacgaaat
    73261 tttcatatga aattttagcc gaacggttaa gagaatctgc ctttcttcta aaaggcgtta
    73321 aaatctctct ttctgatctt cgtggagaag aaccagtcaa ggaaattttt cattacgaag
    73381 aaggaatcaa agaatttgtt gattatctga atgaagaaaa agatacattg acaccagttg
    73441 tttatttttc aggagaaaaa gaaggtatcg aagtagaggt cgcttatcaa tacaatgacg
    73501 gttattcaga aaatgtttta tcttttgtca ataacgttcg gacaaaagat gggggaaccc
    73561 atgaagctgg tatgaaagcg gcgatgacga aatcttataa tgaatatgcg agaaaagttg
    73621 gtttgctgaa agaacgggac aagaatctgg aaggtagtga tttcagagaa gggttagctg
    73681 ctgtactttc tatccgtgta cctgaaaatc ttctgcaatt tgaagggcaa acaaaagaaa
    73741 aacttggtac gccagttgct cgtaccgtag tagataacgt catcagtgaa caaatgggct
    73801 tttatttgca ggaaaatagc gaaatgagcc agatgttggt ccgtaaagca atcaaagcca
    73861 gagaagcgag agaagcagca cgtaaagcca gagaagaaag ccgaaatggg aagaagcgta
    73921 aaaaaggcga atctcttctt tcaggaaaat tgacacccgc acaatcccga aaccctaaga
    73981 aaaatgaatt gtatttagtc gaaggggatt ctgctggcgg atctgctaaa caaggaagag
    74041 acagaaagtt ccaagcaatt ctacctttac gaggaaaagt catcaatacc gaaaaagcta
    74101 aaatgcaaga tatcttgaaa aatgaagaaa tcaatacgat gatctatacg attggtgcag
    74161 gagtcggtcc tgagttttct atcgaagact gtaattacga caaagtaatc atcatgaccg
    74221 atgcggatac agacggcgcc catattcaag tattactgct tactttcttt tatcgttata
    74281 tgaaaccgct gattgaagct gggaaagtat atatcgcgtt accgccttta tataaagtat
    74341 ccaaaggaca aggaaagaag caagtcattg aatatgcgtg gacagatgac gaattggcag
    74401 caatgattaa aaaagtcggc aaaggatata tgctgcagcg atataaagga cttggagaga
    74461 tgaatgcgga acaattgtgg gaaacaacga tggatccgac ttcccgtacg ttgatccgcg
    74521 tccgtatcga tgatgctgcg caagctgaac gtcgagtaac cacactgatg ggtgacaaag
    74581 tagaacctcg aagaaaatgg atcgaaaatc acgtgcaatt tacgctcgaa gaagatggca
    74641 gtatcttaga taaaaaagag gatactgaaa tctctccttc agtttctaat gatttattag
    74701 atgaagaacg agcagataaa aatgaaaaca atcagttatt tgaagtagaa taggaggtca
    74761 cctgatggaa aatcgacaag aagtacaaga attaacttta gaagaagtga tgggtgaccg
    74821 cttcggacgt tattccaaat atattatcca agaacgtgca ctgcctgata tccgtgatgg
    74881 attgaagcca gtgcaacgcc ggatattatt tgccatgaac aaagatggca atacgtatga
    74941 caaaggattc cgtaaatcag caaaatctgt cggaaatatc atggggaatt atcatcctca
    75001 tggtgacatc agtatttatg aagcgatggt ccgcatgagc caagactgga agttgcggga
    75061 agtactgatc gaaatgcacg ggaataacgg gagtatggac ggtgatccac ctgctgcgat
    75121 gcgttatact gaagccagat tatccaagtt aagtggagag atgctagcag atatcgagaa
    75181 agaaacagtc gatctcgtgt ggaattttga tgatacagaa aaagaaccaa cagtccttcc
    75241 agctcgatac ccaaaccttc tcgtcaatgg atcgacaggt atatctgctg gatatgcaac
    75301 agaaatcccg actcataact tagctgaagt gatcgatggc acaatctata tgatcgatca
    75361 tccacaagcg agccttgaaa aattgatgga atatattcct ggacctgact ttccaacagg
    75421 agggatcttg caaggaaaag atgaaatcaa aaaagcttat gaaacaggac gaggaaaagt
    75481 tattcttcgt tcgaaaacaa agatagaggc aatgaagggt aataaacagc aaatcgtgat
    75541 cacagaaatc ccatatgaag taaataaagc gaccttggtg aaaaaaatgg atgagatccg
    75601 tttgaataag aaaatcgatg gaatagctga agtacgagat gaaagtgata gaacaggtct
    75661 gcaaattgtc gtcgaattga aaaaagacgc caatgctcaa ggaattttga attatttgtt
    75721 caaaaacact gagctacaga tcaattacaa tttcaatatg gtcgctatcg accatatgac
    75781 tccgcatcaa gttggactga aagacatttt aagaagttat atcgagcatc gaaagcaagt
    75841 cataacaaaa cgtagtcaat tcgatttagc caaagctcaa aaaagacagc atatcgtaga
    75901 aggattgatg aaagctttat cgattctgga tgaagtaatc gcaacgattc gtgaaagtaa
    75961 agacaaaaaa gacgccaaaa agaatttagt cgacgtcttt caatttacag aagaacaagc
    76021 agaagcaatt gtcacattgc aattataccg tttgacgaac acggatatca cagagcttca
    76081 aaaggaatcc gaaagcttga ttgcgcaaat cacagagttg aataaaatcc tttcaaatga
    76141 caaagagctt ttctctgtta tgaaaaaaga attgcgagaa gtgaaaaaaa attattcttc
    76201 cgctcgtcta acgacaatcg aagacgaaat cgaagaaatc aaaattgata cgcaagtctt
    76261 agtggcacaa gaagacgtaa ttgtcagtgt gacgcgagaa ggctatgtga aacgaacaag
    76321 ccttcgttct tatagtgctt ccaaaccaga agaaatcggg atgcgagaag gcgactactt
    76381 gctatactca ggtgaattga gtacattgga ccatgttctt ctgatcacaa ataaagcaaa
    76441 tgtgatctac cgccctgtcc atgaactacc cgatttgaaa tggaaagatg ctggtgagca
    76501 catttctcaa acaatctcca atctgtctgt agacgaatcg attttagctg ttttcccata
    76561 tcaaaaaatt caagcagaga aaacatttgt attcatcagc aagaatggat tgatcaagca
    76621 aacacgaatg acagagttcg aaccatggcg cacctataag agccgtccgc tcagctgtat
    76681 gaagctaaag gcggaagaag atgaactgat tgctgtgtat ctgaaagaag atcagccagg
    76741 cttagatgtt ttcttagtaa cgcatcaagg aatgggtttg cgctatcctt taacagatgt
    76801 tcccgttgtt ggagcaaagg cagctggagt gaagtctatg aatttgaaag atggagatag
    76861 gattatcaac gggctgcttg tgttagcaga aggtgatacg ccgatcgtaa tcgttactca
    76921 gcgaggagct gttaaacgca tgcttgctca agaaatcagc caaacttcac gtgcgaagcg
    76981 gggagtgacg gtcatgcgtg agctgaaaaa aaatccgcac cgtattatct atatgtcgga
    77041 aggaagatca aaagaaataa ccttgatgaa tcaaaaaggg cagcagttaa cgattgaccc
    77101 aactgatttc cctataggtg atcgaacatc gaatggatca tttgcgatgg atgagaaaaa
    77161 aggtggagaa gtcatcgaag ttatcgatgc tcctgagatt ttcatcgagt cgtaactgtt
    77221 gtagtatttt aatgaagaga cgccatctgt attaatacag gtggcgtctc tttttcattc
    77281 atttttaata aatccttata cgtttgcaaa aaaagatgaa agtgttcaca atgcttaaat
    77341 gttggtatgt caacgttgat ttaaatatat gtaaataaaa cataaaaatt gttaaataaa
    77401 aaacaagaaa acccttgcaa agatagggtg ctgtgttata ctaatcacgt aaaaactgtt
    77461 acataaaaca gaaatttagg aggtccatac aatggagcaa tggaatggat ttaaaggtac
    77521 caaatggaaa gaaggcgtag acactagaga ctttattcaa aataactaca ctgaatatcg
    77581 cggtgatgac agctttttgg aaggcccaac agaagcaaca gaaaaattat gggatgaatt
    77641 gcaaaagtta aatgatatcc aattcgagcg taacggtgtc tatgatatgg acacagaaat
    77701 cgtatcaact attacttcac acgatgcagg ctatttggat aaagatttgg aaaaaatcgt
    77761 cggtctacag acagacaaac ctttgaaaca agcattcatg ccgttcggcg gaatcaatat
    77821 ggctaacaat gcgctaaaaa gcaatggcta tacaccaaac gatgaattga cacatatttt
    77881 cactgactgg cgcaaaacac ataatcaagg tgtatttgac gcttatactg ctgaaatgcg
    77941 tgctgctcgt aaaaacaaaa tcattacagg gcttccagac gcttacggtc gcggacgtat
    78001 catcggtgac tatcgtcgtg tggcattgta tggaatcgac tatttgatgg aacaaaagaa
    78061 aaaagatcat gatatgactg gttatcatac aatgagtgaa gaagtgattc gtttacgtga
    78121 agaaatcact gaacaatatc gtgcattagc gcaaatgaaa gaaatggctg cgaaatatgg
    78181 ctatgatatt tctaaaccag ctgcaaatgc aaaagaagct gtccaatggc tatacttcgg
    78241 atatttagca gcaatcaaat cacaaaatgg tgctgcgatg tcaatcggac gtatctcagc
    78301 attccttgat atctatatcc aacgtgattt ggataatgga gtaatcacag aaaaagaagc
    78361 acaagaattg atcgaccact tagtaatgaa attacgtatg gtcaaattcg cgcgtacacc
    78421 tgaatataac caattattct caggattccc tatctgggct actttatcca ttgcaggtat
    78481 gggattagat ggtcgttcat tagttacaaa gaatgatttc cgtctgcttc atacattaac
    78541 aaatatggga ccttcaccag aaccaaactt gactgttttg tattctgaac accttccaga
    78601 aggattcaga acatatgcta gcagaatcgc tatcgaaagt tcttcgattc aattcgaaaa
    78661 tgataatcag cttcgtgaac aatggggttc tgatgattgt gcgattgctt gctgtgtatc
    78721 aggaacagtt gtcggaaaag acatgcaatt ctttggcgct cgtgctaact tggctaaaac
    78781 actattatat gccatcaatg gcggagtcga tgaagtgact ggcgcccaag ttggaccaga
    78841 atatcgtcca atcacatcag aaatactaga ctttgaagaa gtgaaacata acttcatgaa
    78901 tatgatggat tggttagcag aactatatgt caatacgttg aacatcattc attatatgca
    78961 tgataaatat tcttatgaag cagctcagct ggctttgatg gattctgact tgcaacgcac
    79021 atttgctaca ggtattgctg ggatctctca tgcggcagac agcttgtcag cgatcaaata
    79081 tgcaaaagta aaagcaatcc gtaatgaaaa aggaatagca gttgattttg aagtggatgg
    79141 cgacttccct aaatacggaa atgatgatga ccgtgcagat gaattagttt catggatctt
    79201 ggaatacttc atgggacaaa tcaaacgtca taaaacttac cgcaactcaa aaccaacaac
    79261 ttcattattg acgattactt caaatgttgt ttacggtaaa aatacaggaa atactcctga
    79321 tggccgtgaa gctggaaaac cacttgcgcc aggagcaaat ccaagttaca atgcggaaca
    79381 aagtgggtta ttagctagcc tgaactcaac agctaaaatg aattacggct gtgcattgga
    79441 tggaatttca aatacccaaa caatcaatcc ttcaggtctt ggaaaagaac aagatacaag
    79501 aatcgaaaac ttgcgtaatg tcttagatgg atacttctca aaaggagctt atcatttgaa
    79561 tgtcaatgta ttcagtaatg atttattgcg tgatgcaatg gaaaatccaa tgaaatatcc
    79621 gaacttgacg atccgggtat ctggttatgc agttaaattc cgtgacttga caagagaaca
    79681 acaattagat gtcttgatga gaacttcaca cgacagaatg taaaaagttc gtgaaaaaag
    79741 tttttcgact tagcgtcgaa aggacgttga atagccatcg catcaaaatc gaataatcag
    79801 tatgcttatt tgaaagaaac gatttacagg ggcaggactt gtatgttccg tccctgtaaa
    79861 ttttacacat aacgaagcgg caattgcgaa aaattttgtt cagaaagctt cgcttcgaca
    79921 gctaacttgt acttaaaatg aaatcaaaga aaagatgtga acttaaatgg aagaaaaaac
    79981 aatcggctat gttcattcta tcgaaacttt cggttcagta gacggacctg gactgcgctt
    80041 tgtcgtgttt atgcaaggat gccgcatgcg ttgccaattt tgtcacaatc cagatacttg
    80101 gaatattggc ggagggaaag aatacacagc agatgaactt ttagataaag cagaacgctt
    80161 cagaccttac tggggagata aaggtggtat tactgttagt ggtggagaac ctctattgca
    80221 gatcgatttt ttgatcgaac tatttaaaaa agcaaaagag cggaagatgc atactacatt
    80281 ggatacatgc ggaaaacctt ttacgtatga agaacctttc ttttcacgtt ttcaagaatt
    80341 gatgaagtat acagatttac tgttatttga catcaaacac atcgataatg aagagcataa
    80401 aaaactaacg cattgggaca atgaaaatat tttagaaatg gctcaatatt tgtcaaaaat
    80461 caacaaaccg gtttggattc gccatgtact agttcctgag cgaagtgatt atgatgaata
    80521 tttgatccga ctagacaact ttattcaaac cttgtcaaat gtagacagag tagagattct
    80581 tccttatcat acgatgggaa aatacaagtg ggaaacactt ggtttgaaat atccattaga
    80641 agggatcgaa ccacctacaa aagaacgtgt cgaaaatgct aaacgattgc ttcatacaga
    80701 agagtataca aaatatttaa cgcgataggt cgcatcggaa agaagataag tattgcttct
    80761 ttccgttttt ttgctattat taaataggag aaatcacaaa ggagcgaatg acatgtcaaa
    80821 aattttagtt tttggtcacc aaaatccaga tacagatgca atcggggcag ccattgcgtt
    80881 ttcacacttg caaaatgaat taggtaaaga aacagaagca gttgctctag gtacacctaa
    80941 tgaagaaaca caatacgcat tagaccactt tcagctatct gcaccacgag tagtagagtc
    81001 agctaaagca gaaaatgcag atgtcatgct tgtggatcat aatgaattcc aacaaagtat
    81061 ttcagatatc agcgaagtaa atattttagc tgtagtagac caccatcgta ttgcaaactt
    81121 tgaaacagct aatccattgt actatcgtgc agaaccagtt ggatgtacaa gtacgattat
    81181 tttaaaacta tataaagaaa accaagtaac aattcctaaa gaaatcgcag gaatcatgct
    81241 ctcagctatc atttcagata cattgttgtt caaatcacca acatgtacgc ctgaagatga
    81301 agcagctgca aaagaacttg cagcaatcgc tgaagtcgat ctaaacactt atggacttga
    81361 aatgttgaaa gcaggaacaa atctaagtga taaatcagct gcggttcttc ttgatttgga
    81421 tgcaaaaagt ttcccaatgg gcagttccaa cgttcgtatc gctcaagtca atacagtgga
    81481 ccttaatgaa gtgatggatc gacaagcaga gctagaagca gcaatggaag atgaaatgaa
    81541 agcaaatggc tacgatctgt tcgtattagt tgtcacaaac atcttagaca gtgattcaga
    81601 attacttgtt gctggtaaag gaaaagaaaa agtagaagaa gctttccaaa caactttgac
    81661 caacaaccgt gctttgctta aaggtgtcgt ttcacgtaaa aaacaagtcg tacctcaatt
    81721 gacggctgta tttagctaat caaatggtag tatgaagcat tcaaaatgaa tggataagcg
    81781 attgatataa aaagaaacat agaacatact aaaggccgaa gaaatggagg agaataacag
    81841 tcaattatga ctcttgttct tcctcctttt tacgtaaaag ccttttaagt aaaataaaac
    81901 ggatagaaaa gagaacatat atgaactatt attcaaaaaa taaggaaaac ttttatcaaa
    81961 aactgaccga tgatccgctt ttttcttcat tgaccgatta tctatatgaa catcgagaac
    82021 aagaaacgat tctaagagaa ttgaaaaaag aattttcgca aaataaattt tcccattttc
    82081 ttgatttatt gatcgatgca ggattaatca agagggaaga acgaagatat catttgaact
    82141 ttccaatatt tgatcctaaa gattacttgc aacaagccac ttcggctgct gaaaccatag
    82201 ctgaacaatt gaagagactc tctgttgatg aacaaaaatt agcgatggga gaagttattt
    82261 gggcgtattg tttcgaagat gaacggaaag aagcgtattt ttatggagta agaaacagcc
    82321 gagagacaga attgctgagg acaactgcag gaaatgagaa gtaccgtttt atcacacttt
    82381 cctctataga acacttcccg cttactttgg ctaattactt ttttgtacag aagaatcagc
    82441 ttcctgtaac gaaggcattc aaagaattag ccgaacttat tggagacgta aatgaatcgt
    82501 acttttttga tcaaatagaa gttatcgttg acaggatacg taagaataaa tataaaaatc
    82561 gccggcctag tattttccat cagtctctac ttgtgacgaa tactataaag gaagaagaat
    82621 cattcacatt agaattacct attgtcgaaa aaaacaattt tgagattgaa ttaccaacat
    82681 tggatccttc attgacaatg gaggaaatgg cctttcttaa acgacaaatc ttttctgagc
    82741 tgagcaagaa atttataccg catgcatttt cttatatcaa agaatatgga acagttttag
    82801 tgagtaaaac ctaagagagc agtaagcaaa aattatactg actcttgcag gaggagcctt
    82861 tctcttcctt tatggttaaa agaattattt gagtattttg cctatctacc acctattaga
    82921 ttcactacat ggtctggaaa caaaggaatg caaaaaaatg gtgagaaatg tggaatgaca
    82981 aaggaagtag tgataagaaa agttagattt ttaaataatc aatattatga ttcagtcaag
    83041 tatggcattt tatgggaaga actagctgat tagattagga agtccatttg ataatccaga
    83101 atcactaaga aacgaatggc gagtcattaa taatttatcc aatcttgggt tattctttta
    83161 gattgaagtg tttaaaacta aaaaagcatt tatgaagtcg taatagtcag gcttcaaaat
    83221 gctttttatt ttgtttgttt tttctttgcc acataaatac acctagactg acgatgaaga
    83281 gcatatccaa cagatttcct gcgacttgga tcgtcgaagg gttggtcagt ggcattaaag
    83341 caaggacaaa aaaggaaaac aagctgtaaa taaaacaggt gacaggaact aatcgaaaga
    83401 agagcggaca tttcaattgg ctaaaaatga gtgaaaaaat aaaataagta aaaatggata
    83461 aaatcacgac taaaccattc atgataaaga agaaaagcgt attgtgatta aacgaataaa
    83521 aaagaattgc taaaaaagaa aacgttttaa atgcaatcaa tacgcttgaa gcttcgttta
    83581 acgtaccagg atgtcgatga aaaaaatagg caccgaaata aacagaaaac agtaagccgc
    83641 aaagagaaga caaaatcaaa aaaaacggat tttcttcggc ttctgtgata tcagaatgat
    83701 ccaaaagcaa ccagcctaat gcactagaag gcgcatgtga ggtcttaagg tatgaataac
    83761 atagaaaaaa taagatcgtc aaagttgcaa aaaaagagcc taaatgtaaa aaattagtgg
    83821 ttctacgttg aatttccata atatctccaa attaaattga taagtatata aagtataata
    83881 acaaattgat gagtatatgt cgatgttttt taatcaaaat aataaataaa aactgtctaa
    83941 catttaaaat ttaatttaga tattagacag tttttaagtt tgtgagttat tttccttgtc
    84001 gttttctcac ttttttagtc cagaaaccac ctgaaatata ttttggctca taagaaatga
    84061 taaaagcacg ctcttcgatt tctttgatca ggcgatacag ttcacgttcg ctttttctag
    84121 gagaaagtat ttcgagaact agccgctcac cttccagccc cattgcagaa gtctgtgtca
    84181 caccataacc gtgttctctc agtatacccg gcaaactttt atcttctgcg ctatttgctg
    84241 gcaaaatcgt tgtgaccatg atgtatccta atgccaattt gtcttcaatc aaaattccga
    84301 cactgatacc tactgcgtaa cctaacgcat agacaaataa attcagtgga ttatctaaac
    84361 gatctaaaac aagggataag ccgacgatat aaatcgtgat ctcgaccata ctgacaagtg
    84421 gagcaatcag tcgatagcct ttcattgtca acatgaaacg taacgtgttc agagtgatat
    84481 aagcaaaatt aatgaggaag atcatcccca acatttttgg atcaatcatt tgtaaaactc
    84541 ctttcattta tataacaaca atatcaaaaa aaatcgtaag tgaagaaaaa ttgaaacttt
    84601 atacatacaa aaaaatgata aaatgattat aatagaatta taaagatagg ttaggtgatt
    84661 aaaatgaaaa cggtcaatcg tgtgttttgt gccagccacg tgctaagtct ccttctcagt
    84721 atatacttag gtgtctattc gattcaacag ccaattgagg tagagaacat tgtttttcag
    84781 atgtcgctga cagatggttt aattttaagc gtttttttct ttttgatact gtttattggt
    84841 aatattttcg gtagcgttgc cagttttttg aatttttcta tttatccact cctttcgcta
    84901 gcattaggag tggtgggact ttgttctctg tgcttatttc ccgagccatt cagtcctgca
    84961 tttatattat ttggtacact gaacctgttc cagacaactg ttggagcatg gttgctatgg
    85021 cgatcaggaa atttaatgaa aataggtgag taacaattga atccaattat attgaaacgt
    85081 tctgtccatc atattccagt gttagaagtt gttctgaaag aattaagaga ggaacgtatt
    85141 cccgttgtca tctattatca cggatggcag acaagtaagg agttagtttt gacgcaagga
    85201 agaaaaattg cgcagcaggg cattcgtgtg atcctgccag atgcgatgaa tcatggggag
    85261 cgcaaacagc cggtttcttc tattccatcc tatacatttt gggatagtat ctacggaaat
    85321 ctgtttgaat ttgacacact tatcaagcat ttagaaaaaa gaggtcttct acatgatcag
    85381 cttgcagttg gcggggtttc gatgggggga atgacaacat gcgccttgtt ggctaaacat
    85441 cctcatatag tagcgggcgt gtgtttgatg ggttcccctg cacctttgga atatggaaaa
    85501 gaaatcgtaa ggcgcgcatc ggaatataat tatgtcgtac caaaagacta ttttgatttg
    85561 atttcatggg ttaagagcta tgatttgtca ttgcagccgg aaaagttagc tggacgtcct
    85621 ctgttctttt ggcatggaca agctgacgaa aaaatccctt atatacaaac ggaacgattt
    85681 gtagaaaaaa atcggcataa gtcttacgga aaagaaattg tttttcgttc ctcaaaaaca
    85741 cagcgacata tggtacaaat accactaatg gaagaagctt ccactttttt agcaaaaaat
    85801 ttgataaaaa agtataaata attgaaacgg aaaatcactc atgacgatag aggattttcc
    85861 gttttttatt ttgggctata ataaactctg ttaggaaaat ttggtataat tgatagtaag
    85921 aatgacaaca tgttagaaag gaagagagca tgcccacttt agcagatgtt gcaaaacgtg
    85981 ccaatgtttc aaaaatgacg gtctctcgag tcatcaatca tccggaacag gtgactgacg
    86041 aattgaaaga gttagttttc tcagcaatgg ctgaactgga ttaccgtcca aatattgctg
    86101 caaaagcact tgtcacgaat cggtcgcaga tcatcaaatt atttatactg gaagaaatcg
    86161 acacaactga gccctattac atgaatttgc tgatgggaat cgctaaacgg atcggtaaag
    86221 cgcattattc tctccaatta gttacaaatg atgccttcga cgtcggttct tgtgatggat
    86281 acatcatcac aggtgtcaga aaaaaagact tcgattggat cgaccgtttg gaaaaaccag
    86341 ttgtcttgtt tggggaaaat tctgaaggat atgattatgt agacagcgat aatgaatatg
    86401 gtacagcaaa agcaacgcaa tatgccttag aaagagatta tcaaacgatt atttatatcg
    86461 gtatcgaagt ggacgagcct tttgaaattt caagggaaac tggttattta tctgtgatga
    86521 aggaagttga tcttcctagt aaaatcttgc ggtttccaaa tcattcgaca gaagtagaaa
    86581 gatatatgac agaaaactgg gcagatttta cagataaaac ttgttttgta tgtagttcag
    86641 atcggctagc actaggagca gtaagaggga ttataaatgc tggaggacac ttgcccgaag
    86701 aatttggtgt gattggattt gatggggtat ttttagacca aatcagttca cctaaattga
    86761 caacgatcaa gcaagatatt atacgtatgg gtgaagtatg tggagaaatg ttgttaaaaa
    86821 aaatagaaga aaaaggggcg agtcaaggtt atcgtcgttt ttttcctgaa ctagttatca
    86881 gagagacaac gaattaagtc ttattactat atatatattt atgaaattca tcgctatttt
    86941 cttaaaataa tcagcgcatt gctactgaaa acaatgaatc tgtgctatta ttgagaaaag
    87001 ttccattttt gagaaggatg gtttgaatga aagaaatcag acgaaaacat ttccgttttc
    87061 ctgcgtacga tgatgagtta ggcgtaaaat taaccaacga caagaagcga gtattatttg
    87121 acggacaaga agatcttttg actgaacaga atcagtcccc gtttgaacag atgaaagaat
    87181 ttcatttcac gaacacgaac accgagaaaa tccgtcgcaa gcgtcgtgca acaaatggat
    87241 tgaagtcagc tccgcgtaag gaaaatttgg aaaagcataa aggaaaatta ccggattata
    87301 ccggccatta ccaatcagaa atcacatcga caggacgaaa aaaacttttt ggtgattcct
    87361 ctcgttctgt cagacaaagt gaaacaagga cagagtccaa gcatactaca cgaaacgcat
    87421 ctgttgacac gaaggtgcgg gagcgttctt attttgttcc taaatatgta cccgcatcga
    87481 ttatcccaga ccctagagaa agcaaaattt ctgaggatca tttaatcgaa tcgatgaaaa
    87541 aaacggatga ctcttatctg ttgttcgata cagaaccgac gccgtatcaa gaaaaaagaa
    87601 atggtgagcc gtctgtacga acattcaatc gaacaaaaac gttagaggaa acaaagcagt
    87661 cagaagaaaa aaaatcgaaa aaaagccatg gtatcttaga acgctcatta caaggattga
    87721 tcgatgatca aggaaactct ttgggagaaa atagctattt taaataagtg atatacaaat
    87781 ttatattcgg ctacagttgg aaaggaaacg ctgcggcgtt tccttatttt atactctatc
    87841 cgaaagttta tatcgtatcc tcaaattttt ttgagtttaa gcgaattttt tctcccaata
    87901 agtaagaaaa taatggcaaa ataaaaaa
//
LOCUS       DADVXM010000004        75357 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.004, whole genome shotgun sequence.
ACCESSION   DADVXM010000004 DADVXM010000000
VERSION     DADVXM010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 75357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.004"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            7..525
                     /locus_tag="KB927_000287"
     CDS             7..525
                     /locus_tag="KB927_000287"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6839237.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            653..1336
                     /locus_tag="KB927_000288"
     CDS             653..1336
                     /locus_tag="KB927_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBB6839238.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1645..1718
                     /locus_tag="KB927_000289"
     tRNA            1645..1718
                     /locus_tag="KB927_000289"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1679..1681,aa:Arg,seq:tct)
     gene            1877..2236
                     /locus_tag="KB927_000290"
     CDS             1877..2236
                     /locus_tag="KB927_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBB6839239.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2359..3990
                     /locus_tag="KB927_000291"
     CDS             2359..3990
                     /locus_tag="KB927_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBB6839240.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMLQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4052..4693)
                     /locus_tag="KB927_000292"
     CDS             complement(4052..4693)
                     /locus_tag="KB927_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBB6839241.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    4879..4955
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            4975..5283
                     /gene="rplU"
                     /locus_tag="KB927_000293"
     CDS             4975..5283
                     /gene="rplU"
                     /locus_tag="KB927_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBB6839242.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5310..5654
                     /locus_tag="KB927_000294"
     CDS             5310..5654
                     /locus_tag="KB927_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBB6839243.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5667..5960
                     /gene="rpmA"
                     /locus_tag="KB927_000295"
     CDS             5667..5960
                     /gene="rpmA"
                     /locus_tag="KB927_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBB6839244.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6394..9201
                     /locus_tag="KB927_000296"
     CDS             6394..9201
                     /locus_tag="KB927_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6839245.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9392..9883
                     /locus_tag="KB927_000297"
     CDS             9392..9883
                     /locus_tag="KB927_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6839246.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            9986..10975
                     /gene="manX"
                     /locus_tag="KB927_000298"
     CDS             9986..10975
                     /gene="manX"
                     /locus_tag="KB927_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBB6839247.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11008..11811
                     /locus_tag="KB927_000299"
     CDS             11008..11811
                     /locus_tag="KB927_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBB6839248.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11832..12746
                     /locus_tag="KB927_000300"
     CDS             11832..12746
                     /locus_tag="KB927_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBB6839249.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12829..13203
                     /locus_tag="KB927_000301"
     CDS             12829..13203
                     /locus_tag="KB927_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBB6839250.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13342..13587
                     /locus_tag="KB927_000302"
     CDS             13342..13587
                     /locus_tag="KB927_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6839251.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13759..14823
                     /locus_tag="KB927_000303"
     CDS             13759..14823
                     /locus_tag="KB927_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBB6839252.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15069..15494
                     /locus_tag="KB927_000304"
     CDS             15069..15494
                     /locus_tag="KB927_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6839253.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15487..15936
                     /gene="nusB"
                     /locus_tag="KB927_000305"
     CDS             15487..15936
                     /gene="nusB"
                     /locus_tag="KB927_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBB6839254.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16033..16887
                     /locus_tag="KB927_000306"
     CDS             16033..16887
                     /locus_tag="KB927_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBB6839255.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            16888..18225
                     /locus_tag="KB927_000307"
     CDS             16888..18225
                     /locus_tag="KB927_000307"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBB6839256.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18230..18454
                     /locus_tag="KB927_000308"
     CDS             18230..18454
                     /locus_tag="KB927_000308"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBB6839257.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18456..19346
                     /locus_tag="KB927_000309"
     CDS             18456..19346
                     /locus_tag="KB927_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBB6839258.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19355..20173
                     /locus_tag="KB927_000310"
     CDS             19355..20173
                     /locus_tag="KB927_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBB6839259.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20280..20729
                     /locus_tag="KB927_000311"
     CDS             20280..20729
                     /locus_tag="KB927_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBB6839260.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20747..22429
                     /gene="recN"
                     /locus_tag="KB927_000312"
     CDS             20747..22429
                     /gene="recN"
                     /locus_tag="KB927_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBB6839261.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22484..22600)
                     /locus_tag="KB927_000313"
     CDS             complement(22484..22600)
                     /locus_tag="KB927_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBB6839262.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22673..23629)
                     /locus_tag="KB927_000314"
     CDS             complement(22673..23629)
                     /locus_tag="KB927_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6839263.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23800..24168
                     /locus_tag="KB927_000315"
     CDS             23800..24168
                     /locus_tag="KB927_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBB6839264.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24338..24769
                     /gene="mraZ"
                     /locus_tag="KB927_000316"
     CDS             24338..24769
                     /gene="mraZ"
                     /locus_tag="KB927_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBB6839265.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24790..25749
                     /gene="rsmH"
                     /locus_tag="KB927_000317"
     CDS             24790..25749
                     /gene="rsmH"
                     /locus_tag="KB927_000317"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBB6839266.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25754..26155
                     /gene="ftsL"
                     /locus_tag="KB927_000318"
     CDS             25754..26155
                     /gene="ftsL"
                     /locus_tag="KB927_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBB6839267.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26156..28348
                     /locus_tag="KB927_000319"
     CDS             26156..28348
                     /locus_tag="KB927_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBB6839268.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSTYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28374..29336
                     /locus_tag="KB927_000320"
     CDS             28374..29336
                     /locus_tag="KB927_000320"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBB6839269.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29350..30711
                     /locus_tag="KB927_000321"
     CDS             29350..30711
                     /locus_tag="KB927_000321"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBB6839270.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30737..31825
                     /gene="murG"
                     /locus_tag="KB927_000322"
     CDS             30737..31825
                     /gene="murG"
                     /locus_tag="KB927_000322"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBB6839271.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31840..33060
                     /locus_tag="KB927_000323"
     CDS             31840..33060
                     /locus_tag="KB927_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBB6839272.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33216..34541
                     /gene="ftsA"
                     /locus_tag="KB927_000324"
     CDS             33216..34541
                     /gene="ftsA"
                     /locus_tag="KB927_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBB6839273.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34564..35805
                     /gene="ftsZ"
                     /locus_tag="KB927_000325"
     CDS             34564..35805
                     /gene="ftsZ"
                     /locus_tag="KB927_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBB6839274.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35822..36499
                     /locus_tag="KB927_000326"
     CDS             35822..36499
                     /locus_tag="KB927_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBB6839275.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36513..37112
                     /locus_tag="KB927_000327"
     CDS             36513..37112
                     /locus_tag="KB927_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBB6839276.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37127..37414
                     /locus_tag="KB927_000328"
     CDS             37127..37414
                     /locus_tag="KB927_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBB6839277.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37463..38245
                     /locus_tag="KB927_000329"
     CDS             37463..38245
                     /locus_tag="KB927_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBB6839278.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38266..38973
                     /locus_tag="KB927_000330"
     CDS             38266..38973
                     /locus_tag="KB927_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBB6839279.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39235..42033
                     /gene="ileS"
                     /locus_tag="KB927_000331"
     CDS             39235..42033
                     /gene="ileS"
                     /locus_tag="KB927_000331"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBB6839280.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42082..43608)
                     /locus_tag="KB927_000332"
     CDS             complement(42082..43608)
                     /locus_tag="KB927_000332"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBB6839281.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43623..44270)
                     /locus_tag="KB927_000333"
     CDS             complement(43623..44270)
                     /locus_tag="KB927_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBB6839282.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44454..44783)
                     /locus_tag="KB927_000334"
     CDS             complement(44454..44783)
                     /locus_tag="KB927_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBB6839283.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            44960..45688
                     /gene="sfsA"
                     /locus_tag="KB927_000335"
     CDS             44960..45688
                     /gene="sfsA"
                     /locus_tag="KB927_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBB6839284.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45704..46717
                     /locus_tag="KB927_000336"
     CDS             45704..46717
                     /locus_tag="KB927_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6839285.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46717..47994
                     /locus_tag="KB927_000337"
     CDS             46717..47994
                     /locus_tag="KB927_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6839286.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48057..50759
                     /locus_tag="KB927_000338"
     CDS             48057..50759
                     /locus_tag="KB927_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6839287.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            50911..51228
                     /locus_tag="KB927_000339"
     CDS             50911..51228
                     /locus_tag="KB927_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6839288.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51258..51578
                     /locus_tag="KB927_000340"
     CDS             51258..51578
                     /locus_tag="KB927_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6839289.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51686..53146
                     /locus_tag="KB927_000341"
     CDS             51686..53146
                     /locus_tag="KB927_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6839290.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53214..53435
                     /locus_tag="KB927_000342"
     CDS             53214..53435
                     /locus_tag="KB927_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839291.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53466..53648
                     /locus_tag="KB927_000343"
     CDS             53466..53648
                     /locus_tag="KB927_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBB6839292.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53648..54061
                     /locus_tag="KB927_000344"
     CDS             53648..54061
                     /locus_tag="KB927_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBB6839293.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54184..55365
                     /locus_tag="KB927_000345"
     CDS             54184..55365
                     /locus_tag="KB927_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6839294.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55436..55600)
                     /locus_tag="KB927_000346"
     CDS             complement(55436..55600)
                     /locus_tag="KB927_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839295.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55754..55827
                     /locus_tag="KB927_000347"
     tRNA            55754..55827
                     /locus_tag="KB927_000347"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55788..55790,aa:Arg,seq:cct)
     gene            complement(55896..57035)
                     /locus_tag="KB927_000348"
     CDS             complement(55896..57035)
                     /locus_tag="KB927_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6839296.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEVK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINAVFDSLYKNDN"
     gene            complement(57145..57795)
                     /locus_tag="KB927_000349"
     CDS             complement(57145..57795)
                     /locus_tag="KB927_000349"
                     /inference="COORDINATES: protein motif:HMM:NF023043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBB6839297.1"
                     /translation="MKKNLILGFICTSILTLGACSSPSNNATNSETQKTINSLKKENE
                     ELKKQIASQSNDTEENSESIDNASKEKTLPVVGILEYTISSIKTEQVTNDEDNFTNAE
                     YNFSGIENFPEKYYRTTISYKLKNKATSPFSLSSYQASLIDGDGMEYSRTAGEYFLYD
                     ENSNSLVQPETTTSGVFYLLSKNKPNLSTFKLNASKQFTDDFTAEPIGEAGTTEYK"
     gene            complement(57932..58585)
                     /locus_tag="KB927_000350"
     CDS             complement(57932..58585)
                     /locus_tag="KB927_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839298.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETNISKTKET
                     TEISSSTSKSTSKTDSSSTVTSSNQATAKPSPTVISSSQDTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNTEAQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFSKYGIQ"
     gene            complement(58635..59063)
                     /locus_tag="KB927_000351"
     CDS             complement(58635..59063)
                     /locus_tag="KB927_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBB6839299.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRDRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKKIEELKNLYGLPESAYRFLI"
     gene            complement(59068..59442)
                     /locus_tag="KB927_000352"
     CDS             complement(59068..59442)
                     /locus_tag="KB927_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6839300.1"
                     /translation="MSLVTKIKELADEKHVTIAEVERQVGISNGQIRRWDKASPKSEN
                     LKKVADYFGVTTDYLLGNNNVPKWATKEEVVELDKLLDSNVNMSYGGETLTPEQIQRV
                     KDILIATFWDIVKEDKEKGKKM"
     gene            59745..59930
                     /locus_tag="KB927_000353"
     CDS             59745..59930
                     /locus_tag="KB927_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6839301.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALVGISGAYLSDILNGNRDG
                     KKAQEHIETVKKILGIQ"
     gene            59943..60281
                     /locus_tag="KB927_000354"
     CDS             59943..60281
                     /locus_tag="KB927_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBB6839302.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            60268..60447
                     /locus_tag="KB927_000355"
     CDS             60268..60447
                     /locus_tag="KB927_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839303.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(60490..60960)
                     /locus_tag="KB927_000356"
     CDS             complement(60490..60960)
                     /locus_tag="KB927_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839304.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            61047..61745
                     /locus_tag="KB927_000357"
     CDS             61047..61745
                     /locus_tag="KB927_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBB6839305.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            61923..62264
                     /locus_tag="KB927_000358"
                     /pseudo
     CDS             61923..62264
                     /locus_tag="KB927_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            62257..62928
                     /locus_tag="KB927_000359"
     CDS             62257..62928
                     /locus_tag="KB927_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBB6839306.1"
                     /translation="MSENKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            62934..63620
                     /locus_tag="KB927_000360"
     CDS             62934..63620
                     /locus_tag="KB927_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839307.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            63627..64478
                     /locus_tag="KB927_000361"
     CDS             63627..64478
                     /locus_tag="KB927_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HBB6839308.1"
                     /translation="MADNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIEVLDNGAIYMSDI
                     QSFIGKSSTEADRKRKYRKEIEEAKQNLITSGQMSDKCPDKTTPELEIELEKDIELEK
                     DIENVTPSKKSKAKPVRHKYGEYKNVLLSDEQMEKLKIEFPNDYQERIERLSEYCESS
                     GKTYKNYLATIRSWARKEKSEPKNASGAYKRTGRREKLPEWAIDQEAYLKKKALERAN
                     RQSKAPF"
     gene            64490..64759
                     /locus_tag="KB927_000362"
     CDS             64490..64759
                     /locus_tag="KB927_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839309.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGINNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLSELEQV"
     gene            64764..64928
                     /locus_tag="KB927_000363"
     CDS             64764..64928
                     /locus_tag="KB927_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839310.1"
                     /translation="MDLKTFTAQIELMHQEALRQSASYEDKWLNTFHGGRESALDQVL
                     KLLKGERRDG"
     gene            64921..65223
                     /locus_tag="KB927_000364"
     CDS             64921..65223
                     /locus_tag="KB927_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839311.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVTEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEKK"
     gene            65220..65531
                     /locus_tag="KB927_000365"
     CDS             65220..65531
                     /locus_tag="KB927_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBB6839312.1"
                     /translation="MNELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            65528..65746
                     /locus_tag="KB927_000366"
     CDS             65528..65746
                     /locus_tag="KB927_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HBB6839313.1"
                     /translation="MIGLTIFWCAIGGLLAFLGYYLICESRKGRKYTVTGIVLLIIGI
                     LVAVGAELNLYVNGTQEDLVRFMFWMKN"
     gene            65757..66572
                     /locus_tag="KB927_000367"
     CDS             65757..66572
                     /locus_tag="KB927_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBB6839314.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            66711..67067
                     /locus_tag="KB927_000368"
     CDS             66711..67067
                     /locus_tag="KB927_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBB6839315.1"
                     /translation="MDLITQYSDIILKKIMAKIQKDKKAKERAELVKLEMAETGVGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKAHSIQHGFI"
     gene            67054..67272
                     /locus_tag="KB927_000369"
     CDS             67054..67272
                     /locus_tag="KB927_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839316.1"
                     /translation="MDLYDIESGATVSVESDHLIISFADERQIIIWVVDDMLYPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSK"
     gene            67269..67667
                     /locus_tag="KB927_000370"
     CDS             67269..67667
                     /locus_tag="KB927_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HBB6839317.1"
                     /translation="MIPKFRAWDKRENTMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVEIFEGDVVITSKGAIGYVAYLQQEAGFVVVLKKSDYRLG
                     HRNTGESYDVATAHEVIGNIYENSELLEVE"
     gene            67664..68002
                     /locus_tag="KB927_000371"
     CDS             67664..68002
                     /locus_tag="KB927_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839318.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            67999..68229
                     /locus_tag="KB927_000372"
     CDS             67999..68229
                     /locus_tag="KB927_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839319.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            68236..68439
                     /locus_tag="KB927_000373"
     CDS             68236..68439
                     /locus_tag="KB927_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBB6839320.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASETIRKFGISILNDDRKWEAER"
     gene            68436..68741
                     /locus_tag="KB927_000374"
     CDS             68436..68741
                     /locus_tag="KB927_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839321.1"
                     /translation="MKLKDGFYTDAYGIGGLMMDLPTKNPIKQEESEIKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVINNGIKN"
     gene            68725..69018
                     /locus_tag="KB927_000375"
     CDS             68725..69018
                     /locus_tag="KB927_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839322.1"
                     /translation="MELKIDKVTFEEPAFQEMDERIAELVEKKQDELIALLEKKYQFP
                     KYMNKMQAAKYLGVSYNTMMDKYVPAGLKMGIVNGVIRISKEECDRFMKEHQK"
     gene            69278..69694
                     /locus_tag="KB927_000376"
     CDS             69278..69694
                     /locus_tag="KB927_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBB6839323.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            70010..70216
                     /locus_tag="KB927_000377"
     CDS             70010..70216
                     /locus_tag="KB927_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839324.1"
                     /translation="MLNKASDQVEQLQETLDEIAIVNKAESENSSFFVKANWNIDLPE
                     GDINNPVAEPIKYNPSKAKLDKVH"
     gene            complement(70170..70418)
                     /locus_tag="KB927_000378"
     CDS             complement(70170..70418)
                     /locus_tag="KB927_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839325.1"
                     /translation="MKITAAITKEQGVTFTVVVVKNGVISSSHREQVRSSIPRNFPRP
                     IILAEQSHGKMKYHGRTDIVKFLSNVPYQALPWKDYTL"
     gene            70777..70989
                     /locus_tag="KB927_000379"
     CDS             70777..70989
                     /locus_tag="KB927_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839326.1"
                     /translation="MNEKQLSELFKLNESNQTAEATFYEAQKSLALIAKQAKYFYDQL
                     ILQGFNEGQAMEFMMRTFSASNQQKE"
     gene            70996..71223
                     /locus_tag="KB927_000380"
     CDS             70996..71223
                     /locus_tag="KB927_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839327.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIIEMTREAT
                     PNEIDKYNLRYCGHGYWKDEYIQQNIERYIK"
     gene            71220..71504
                     /locus_tag="KB927_000381"
     CDS             71220..71504
                     /locus_tag="KB927_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839328.1"
                     /translation="MNDNYDYIKLIEKIRAEKDMDELANLFMNIISLVGLKMDEVAAL
                     NYFIAEQTIRAEHNAKFLKDRLDLDVKGLGVEGIFKVQEALVNVYVEKMQ"
     gene            71545..72117
                     /locus_tag="KB927_000382"
     CDS             71545..72117
                     /locus_tag="KB927_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839329.1"
                     /translation="MKLKDYIREGYNIVTTPNLAYKIQEDYPNVLVFTDRALDAIPIG
                     KLLVDRYYSNNPAVLSAKPLQNAYAIERFTCEFTGYETVVPMTGETGRKVIQQIKKRI
                     AELTLDDGSNTNLLEIKLRDTDSVPEVYYKGQRMDEMPIGLVDITYHWHTEEYECQVP
                     KGANDITIEYYDSHNNKYLDRKIIGHKRDM"
     gene            72118..72429
                     /locus_tag="KB927_000383"
     CDS             72118..72429
                     /locus_tag="KB927_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6839330.1"
                     /translation="MIDVSTKQARARFYGSTEWRKLRSQCLERDHYECQWCKAEGRLT
                     TQHDSILEVDHIKELEYHPDLALDINNLRTLCKDCHNKRHNRMKYRGQQKKRKWDDEW
                     W"
     gene            72420..72680
                     /locus_tag="KB927_000384"
     CDS             72420..72680
                     /locus_tag="KB927_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839331.1"
                     /translation="MVVRKTANRDDVKRAEAIAMVDKAIDKLVLFKSQLIEETTTVED
                     ISINNRLIGNANEVTGTFNINVDIDYTLSPFAHIVESNEQDG"
     gene            72848..73402
                     /locus_tag="KB927_000385"
     CDS             72848..73402
                     /locus_tag="KB927_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016630802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6839332.1"
                     /translation="MIGLNSKLVGTRMKQKRIEKGLTQADVATKSGISSRYYGSIENG
                     KNSPSIETLNSISIVIGCSLHFLLNDRMDDMEKRVELEKKRLQKIFDKIPHDKLNLVE
                     GLIIQAARLRVLLDDNWKDIIENGEYEKFKQSENQIAYDRKRPIVENYDNRDKTYQAI
                     VKQLTDLLPQGTRADKKSKLLGRK"
     gene            73405..75096
                     /locus_tag="KB927_000386"
     CDS             73405..75096
                     /locus_tag="KB927_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6839333.1"
                     /translation="MLFNQHVDQYIRKWKSGELILNEKRIQLLKLIEKEILPRDDIYY
                     FDEEQINNYIEFSQAWYFELDEWEKFISAFIFLFYKEDDEVVFDEFVINMGRGGGKNG
                     FISTLANYFVSSLHGIDYYDVSIVANSEKQAKRSFQECYRVINKKGNEDLKEEFEAYK
                     SSLTGLETQSVFEYKTSNASSQDGGREGAVIYDEYHEMENTDIVDVFSGGLGKVDHGR
                     QFFIGTKGFVREGYFDIKYRECEDILNGLSEFKGVFPYICELDAIEEMDDPKNWPKAN
                     PALQPPLNKRGKRLFNEVMKKYKKLAKEPSGRSAFVTKRMNFLEDNMENSVASREEIM
                     ATNRPFFELDTVPIGSLDFGSVRDFATCGLLFKNRKKSEYAFKSFTFAMKNFCDVHYG
                     YSLKEQLVGSEKRAPIKTWEKMGLMKVIDEPSLNPKYIVDWFIQAREEYGVRVIVVDN
                     YKADILGPMLEKEGFEVVRLKRPSSLHPLLAPRIEDGFANHKFIFGDNPLMRWFTNNV
                     YVKETQAGKQFLKKEEVKRKTDGFQAFVHALYKATELDEQIDYDDAFDMLDEIEF"
     gene            75128..>75357
                     /locus_tag="KB927_000387"
     CDS             75128..>75357
                     /locus_tag="KB927_000387"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839334.1"
                     /translation="MRIKGKNISWVFYMLGILAFTFVAIKLSEIIIPNDSVVSKNLVL
                     ERAKLIISILGPALTLIVFVRTIQTQLESSKN"
BASE COUNT        25273 a        12380 c        16042 g        21662 t
ORIGIN      
        1 aaaacgatac ctgattacaa aaaaataact tttataagtt ctataacgtt gattatattt
       61 ttaattctta ttcttctcgt cgtcttggtt ccccgaattt ttggtttgac tccttatatt
      121 attgaggaca aagaaatgag tccatattat gcacaaggaa atctgatata tgtacgaccg
      181 aaaaatacaa atgagatttt agtcggagat attattacat attatgaaaa ttcaggaaaa
      241 aaaatctcga cccgtcgcgt aatagccgtt gaaaacaacc acgaagattt ttatacaaaa
      301 gctgatacaa agacttatat tgagcctgga gtagtaaaaa agagaaatat tatcggtagt
      361 cccatctttc agattccata tattggacta gtcctttcaa aaacggcatt tgcatggatt
      421 caggggttat tctttacgat tgctttttgc ctaacaggaa tcacagcatg gaataccttt
      481 gtagagttga aaaagaagcg gagacgaaca cagaaatttt tgtaagaatg ttaaaaacat
      541 aaatgtattc cagagatcca acgactcttc tgaacatgaa acacgagaaa acactcatgc
      601 agcttgtaga tttagtcagt tgttcgtata atgtgtgaag aggaggagta gtatgcgcaa
      661 tgaaatgatg catcgtcctg tagtcaaaga agaactattg gattttatgc gtacccagca
      721 aaaaaaatta ccgggtgagc taggcaaact ggaagaagaa gctcatgtag cagaagtacc
      781 agttattccc catgaaacag ttgtattttt gaaattttta cttggacagc ttcagcctga
      841 acgaatcttg gagatcggag cagctatcgg tttttcatca agtgtcatgg ccacgacaat
      901 cggagaaaac gctcatgtta cgacaattga tcgtttcgat gtcatgatcg agaaagctaa
      961 aaaaaactat gaacgtctag gactgacaga taaagtgact ttgcttgaag gtcaagcagc
     1021 agatatcttg ccggagttgt ctggtccgta tgactttatt tttatggata gtgcaaaatc
     1081 aaaatatatt gaatttttac ctgaatgctt acgtttgtta agaaaaggtg gcgttttgat
     1141 ggtagatgac atcttccaag gaggaacgat cttgctccca gatgaagaga ttccccgtgg
     1201 caaacgagct atccatcgta aattaaatga atttcttcgt gttgtgatgg atcatcccga
     1261 tttgacatcg acaatcttgc cattaggtga tggtgtgatc ttaatgacaa aggaatcaga
     1321 aacaatcgag ttgtgataca tgattatggc agcctgtaga taatcgattg aatcgagggc
     1381 tcaattcgaa cttgatgtaa aagtttctat atttgtaagt caattaaagg atacaggaaa
     1441 tctaaataaa caggagtagc atgaagtcaa tgtagctcct gttttcaatt gataacctta
     1501 gaacagctga aggagaatgt ctcgttttaa aagattgatt tagtagttgg gccaaaataa
     1561 ttcattattt gctaattaaa taactatttc gtattgacag aagcaattta attatctata
     1621 attattgatg ttccgctgat tcttgtcata gtagctcagc tggatagagc atccgccttc
     1681 taagcggacg gtcgggggtt cgaatccctc ctgtgacgct aaaaaaccgt tagaaactga
     1741 ggtttctaac ggtttttctt tgttttttgt gccaatattg tttgttttca aaggcaaata
     1801 aaataaaaaa acatccttat cgagtacaat tataaggagc aaaaaaataa aactcatcag
     1861 aaaagaggaa gaagatatga cgatactatc tagaatttta gtgactctag ttgcaattga
     1921 atttttttat atcatgtata tcgaaacggt gagaactgat tctgacacga caagtagggt
     1981 ttttaaaatg agtaaagaag agttaagcag aaaatctgtt caaacattgt ttaagaacca
     2041 aggagtgtac aatggactat taggagtggg actactttat ggagcttatc tttcttccgc
     2101 atctaaagaa atcacaagta tgctattaat atctattttt tttgttgcat tatatggcag
     2161 tttgactagc gatcgttgga ttttactcaa acaaggtggg ctagctctgt tggcattgct
     2221 ttctattttc ttataaatat agaaaaaata agaatttatc taacaggaaa ctttgtgaaa
     2281 aatattactt tatctcatga aatatgatat tctaatgaat ggtattttag aaaatttcat
     2341 gaaaaaggag ttagataggt gttcaaaaat tatgtttcct cactaaaaaa agaattttca
     2401 ggttatgatc tttcaagatt tcagaaagat cttttggctg ggatcacagt agctgctgta
     2461 gcattgcctt tagccttggc ttttggggta tcaagcggag ctgatgcggc cgcaggtttg
     2521 attacggcta tcattgccgg tatcgttatt ggcggtttat caggcggttt ttatcaaata
     2581 tcaggtccga caggtgcgat ggcagctatc ttgatgtcta ttgcggcaac aaagggaatg
     2641 caaggtgtat tgcttgctac ttttttagcg ggtctatttt tacttgcagc aggacttttc
     2701 cgattaggaa cactgacttc ttttatccca gcacccgtaa ttacggggtt tacttcaggt
     2761 attgctatca ttattgcatt aggtcagatc gataatttat ttggtgttca ctcggaaggt
     2821 acaaacgtta ttgaaaaact aagtagttat caaacgatag gatttccgat aaacacagcc
     2881 tctttgatca tgggagggct agtcatttta gggatgttta tctatccaaa aaaatgggcg
     2941 aaacgaatgc ctagttcgct gctggctatc attttggcaa cagcagttat gctattgttc
     3001 catttaccag tagcaactgt gggtaagatt ccacaaacat tgatcagtag taatcgtttg
     3061 aatatgggag attttagctt ttctgccttg caacaagtgg cagttccagc tattagcatt
     3121 gctttattag gaatgattga aagcttgcta tgtggtgctt cggctggccg aatggcaaat
     3181 aagcccttag atagcaatca agaattaatg gcgcaaggaa ttggaaatct gttgcttcct
     3241 ttctttggcg ggattcctgc tactgcggcc atcgcccgta caagcgtggc catcaaatct
     3301 ggtgcacaaa ctagattagc tggtatgata catgcagttg tcttactgct ctccatgctt
     3361 gtttttgcgc cagtgatgtt acagattcca atgccagcac ttgcaggtgt tttgattgtg
     3421 acggcttggc gtatgaatga atgggaaacg atcaaggagc tatttactaa taaatattgg
     3481 tcagcagttc tattgtttat ccttacgatg atttgtacag ttatctttga tttaagtatt
     3541 gctatcgtga tcggggtgat cggcggctgt gtattttttg ttgtcaaaag cgctgctatc
     3601 acgatttcat tagaaacgat cgattggcaa agaatggggc tgccagaaac ggaaaagctg
     3661 aataactgga cagtagtgta tattagtggt ccactgtttt ttatgtcttc agaaaaactc
     3721 aaaaataaat tggaagaact aaatcatcac gatggtgtca ttttctccat gcgaggcgta
     3781 ccaagtattg atttgacggc acgtgcagtt tttgatgaat ttcaagaaaa agcagagcaa
     3841 agaggacaaa cgattatcta tacttccttg cagccagaag tagaaaaaca actttctcac
     3901 ttgtgggaac atacattcac gcatcaacat caaacagttg ctcatgcgtt gacagcttta
     3961 catgcgaaat atactgcaat tagccattaa aacaatgaaa aagaacagac aagactgtaa
     4021 actgaagatt ttatggtctt gtctgttctt tttaatattg ctgtaaaagt gaagctagta
     4081 cttgccagtc ttgatggata acaggtacaa gggagcgatt gtagaaaata gctgctggat
     4141 gaaaaagtgg aagaattcga tagttttttt ctgaccattc gtaggcatcc ttttgttctg
     4201 ttaattgtaa gacaggccct gtatagagtt gaccatgatt tttggtaacc gtatattctt
     4261 tgccaagtaa acgttgaaga ccaatgtttc caagtgtcgc aattaatttt ggctggacct
     4321 tcatcagttc gtaatccaat attggtgcat gcgcaaatac ttcggaacga gtaggtgtcc
     4381 gatttggata aacagtttct gactgttgtg tccgtttatt gatccgatga gtcacgcgat
     4441 acgggcggct ccttacagca ctggtgatat acacctcttc tcgtgttaag ccagttgaag
     4501 aaagtgcctg catcaattct tttccagctt gaccgctaaa aggaacatgc gtatcaatct
     4561 ctgttttccc tggggcttct cccacgagca tcagtttagg atgaagaggt ccttgcccag
     4621 cgataaatcc ttctacagga cggccgttca ttcttaaaga agcttcttgt atcagttctt
     4681 ttgggtattc catttatgct cctccttttt cttttattat aagaataaaa gaaacacaat
     4741 gcgactattt tatttggtag aactgtgagg atagaaaagc agaagtattg cttgaatttt
     4801 tgttttactt tttgatttta aatttagttg actaacggtt gctgttctgg taagctagta
     4861 ctgttgtaat tgtggactcc acagctacaa ccgctcagaa caagtaataa gcacagcata
     4921 tgctgtcact tcggatggcg agtctaagta tatcagaagg aggtgcttta tagcatgtac
     4981 gcaattatta aaactggtgg taaacaagta aaagttgaag tgggacaagc aatctatgtt
     5041 gaaaaacttg acgttgaagc aggagaaaaa gttgtttttg acgaagttat cttagtaggc
     5101 ggagaatcta caaaagtagg cgctccaact gttgcaggtg caactgttga aggtactgtt
     5161 gaaaaacacg gcaaacaaaa gaaagtcgtt actttcaaat acaaacctaa aaaacattca
     5221 caccgtaaac aaggtcatcg tcaaccatat acaaaagtgg ttatcgacgc gatcaacgct
     5281 taatagcgtt tgagaaagaa ggcctatata tgatcaaagg aacatttaag cgaaatgacg
     5341 caggtcagat cgtttcattc actttgaccg ggcatgctga tgctggtcct tatggaagtg
     5401 atatcgtttg tgcgggtgtt tctgcgttag cgatcagcac tgtcaacggg attgcctcat
     5461 tagccggttt tgagccgatt gttgaaatga atgaagaaga aggcggttat ctttataccg
     5521 aagtcacttc aggaatgaca caagaacaaa acaatattgc tgagattcta ttagaaaatc
     5581 ttttattagg attacaatcg atagaagctg aaaactcaga atatatccaa attaaaacaa
     5641 ttaatgataa ataggaggtg cagaccatgt tgttatctat gaatctacaa ttatttgccc
     5701 acaaaaaagg tggcggttct acatctaacg gccgtgactc agaatcaaaa cgtctaggtg
     5761 ctaaacgtgc tgatggacaa acagttacag gtggatcaat tctttaccgt caacgcggta
     5821 caaaaatcta tccaggtgta aacgtgggta tcggtggaga cgacacttta tttgcaaaag
     5881 ttgatggcgt agtacgtttc gaacgtaaag gccgtaacaa aaaacaagtg tctgtttatc
     5941 cagtagctca agaagcttaa ttgaatctta tgattaaaga ggttgtgaca agacttttgt
     6001 cacagccttt tttgtttata aaaataaaag ttgtagtgga ggctacgaag tttactttgt
     6061 ctttttacac ttaatatttt tttgccaatt tggaatcagg atgttttgat aactatcgtt
     6121 ttcaattgat ggaagctata ttgtttgcta tcagtgaaat aattatatgg taaacagtgt
     6181 tctttttctt gtttccatta taaaaatcgt atcgggattt ttcgttcttt taaattgaac
     6241 atttctatct atccgcgtgt tatcaacaaa acaaaatcag gtaaatagtt gacgaaacag
     6301 aaataaatac atagtattat gttttgaagc ctaagtacaa tagtctatag aaaaggagcg
     6361 ataccattgg caaaacgcat tgaccgaatt tatatgtatg tcaaagaaaa aaccgctcat
     6421 ttaacaaagg cagaatatga tcaaggagta acaacacagg aaattgctga agtgttaggg
     6481 attcagcgaa caaatagcag taaagatctg aatcagctag tgcgcgaagg aaaactgata
     6541 aagacagacg gacgaccagt acgttacata tatcaaacac tcgttacgca cgtaaagcca
     6601 gttacaaaac atgtagtcag ttacaaagaa acgccggtct ctgaagaaaa aaatacactc
     6661 caaatagata ctaaggatat ctttgcaaaa atcattggag ctaacggcag catgaaaaat
     6721 tcagtggaac aggcaaaagc tgcgattttg tatccgccaa gaggattaaa ttgtttgatt
     6781 acaggaccta ccggatcagg aaagacttat tttgcacacg cgatgtatca ttttgcaaaa
     6841 gcgcatcatg taatagatga ggaaacggaa ctgattgttt tcaattgtgc tgattatgcc
     6901 aataaccctg agcttttgat gagtcattta tttgggtacg caaaaggtgc ttttacaggc
     6961 gcagatgaag aaaaaatggg gattatcgat caagcggatg gcggtatgct gtttttggat
     7021 gagattcacc ggttgccgcc tgaaggtcaa gaaatgatct tttactttat ggatcatgga
     7081 acttacagtc gtcttgggga aacaacgaaa tcccatgaag caaatgtacg gatcgtaggt
     7141 gcgaccacag aagacccagg ttcttctcta ttagaaactt ttgttcggcg tatcccaatc
     7201 aatatcaaac ttccggcttt tgaaaaacgt cctgcaaatg agaaagtcga tttagtaaaa
     7261 atcatgattg cccacgaagc aaaccgcacg cagcgaaaga tttctttgac agaagatgta
     7321 gcaaaagcat tgatcggcag tgtgacctat ggaaatatag gacaattgaa gtcaaatatc
     7381 cagttagtat gtgcacgagg atttctaaat catatgcaat cacccgaaat ctcgatcaca
     7441 atcgatgatt tgacagaagg gattcgtagc ggattgattc aattagcaag caaccgcagt
     7501 gcaatggcag agctttctaa aatattggag ccaaagataa ctgtagcacc aaatgatacg
     7561 atcatgaaaa tccaatcgga ctcctatgag ttaccttata atctatatga tatcatcgga
     7621 gataaagcag ctttactgaa gtcggatggt ttggatcaag aagcaatcaa tcatttcatt
     7681 tctacagata tcaacatcca tctgaagtct ttctataaag accatggttt ttcttttaat
     7741 gcagacagca aattagcaga atttgtagat ccgaaaatca tagaagtgac caatcagatt
     7801 tatgtaatgg tcaaaagatc tttaccatat gagtttcagc aaaactttat ttatgctatg
     7861 agcttgcata tcagttcttt tttgaaaaaa atcaacttag gagaagaacg gcatacgaat
     7921 gataacatcc gtgagatggc ttttgatttt ccagatgaat atgctgttgc gaaagaagtg
     7981 cgtagttata tcgaaacgta ttttcaagtg gagattccag aaagtgaaga ctattacttg
     8041 accgttctac tcgtctcgtt acgggcaaat caagcaagcg gcagaatcgg tgtagtcgtt
     8101 gcagctcacg gaaacagcac agcaagcagt atggtccaag ttgtccaaca gttgttagat
     8161 gcagagaacg tacgagcagt agacatgcct ttggatatgg atccgaaaac agcattggac
     8221 cgaattgaac gcaatgtaca agaagtagat gaaggaagcg gggtcatact cttagtagat
     8281 atggggtccc ttgcgtcgtt taattcgcaa attcaaagag acactggaat tccagtacgt
     8341 actgttgata tggtaacaac ttctctagtt ttggaaactg tacgaaaggt ctcagtatta
     8401 gggacagatc tagatatgtt gcatgaatca ttgaaaaatt ttcgaggtta cgcagaaata
     8461 tcttctgtag aatctgttca ggaagcaaaa cctattcata agaaaaaagc tgttttggct
     8521 atctgcgcat ctggcgaagg tacagcacaa agaatcaaag aattgatcga acgagcggta
     8581 aacaagcgtc aagaaacaga attagaagtt ctagctttgt cgattgtgga agtgaaagaa
     8641 gaactgccag ttatccaaaa agaatatcag atcatagcta ctactgggat tactgatttg
     8701 aatatccaag ccccatttat tcctttagaa cgttttattg atcaaaatat cgaagtcatt
     8761 ttggatcagt tgctgatgga atcagaattg gaggaaactg aattcatctc cctagatgaa
     8821 gagtcagcta aaaatacgtg tgttgagttt atctctgata acttcatctt tattaatggt
     8881 agtaagttaa tcgatccaat gtggcaattt tctacacaaa tctctcagac gacgggaatc
     8941 ggcgatgaag aatatggatt caaaatcaac ctagtgatgc acacagcagg aatgatcgaa
     9001 cgtattattc ggaatgaacc attgactgtg gaagaaaacg aattgacaaa tacaacgaat
     9061 gatcctcttt atagccaatt ggcagcctca gttgttctgt tggaagatca gataaaagta
     9121 aaagtgccga tagaagaaat gtattatctg ctacgtctag tccataatca gttagataaa
     9181 aaagaataca ctgtgccatg aatacacaaa aacgatacac ttttatagtg tatcgttttt
     9241 gtgtattggt taagaatcct ttaaattcaa ttagtgtatc gtaaaaaagt tggcacgctt
     9301 tttgcttata gtagtgtgtg ctaggaggtg gttgttcaca cagaaatgat aggggtttct
     9361 gtgaagtagt gaggaagaag gagttttgca gatggatatt cgattggcac gtatagatga
     9421 tcgtttaatc cacgggcaag tcgcaacagt ttggtcgaag caaacaggtg ttgaacgtat
     9481 cattgtgatc agcgatgtag tcgctcaaga taaattgaga aagtttctac taaaagaagc
     9541 tgcaccgccg gggatcacag caaatgtaat aaccgtgcag aaaatgattc aaatctatca
     9601 tagtggatta ttatcacgag caaaagtgat gcttttattc accaatcccc aagatgttga
     9661 agcggttgtc cgctgcggtg tacagttgaa gtcgttgaat atcggcggta tgagttttac
     9721 tgaaggcaaa tcaatgatta ccaattttgt ttcagtaaat caacaagata ttgattcctt
     9781 tcgttacttg aacagtcaag aagtggagtt agagattcga aaagtacctg ctgacaggaa
     9841 aatccttttg atggaactac tagcgaaaat caaaaaggtg tagcaagaat ggttgttgga
     9901 aaaggtcaaa taattctgtt gtaatggtta gcaattatta atatttttga atttgttaca
     9961 acaaaagtaa ataggaggta taaatatggt agggattatc ctagcaagtc atggacaatt
    10021 tgctgaagga atcttacaat ccggttcaat gatctttggc gaacaagaaa acgtcaaagc
    10081 cgtgattttg aaaccaagtg aaggtccaga tgacttgaga gccaaattgg aagaagcggt
    10141 tgcttctttt gataatcaag acgaagtgtt attcttagtt gatttatggg gcggaacacc
    10201 gttcaatcaa tcaaacacat tattcgaaga gcacaaagat aaatgggcaa tcgtcagcgg
    10261 tttgaattta ccaatgttga ttgaagccta cgcatcacgc ttttcaatgg aatctgctca
    10321 tgaaattgca gcacacatca ttgaaacagc aaaagacggt gtaaaagtaa aaccggaaga
    10381 attagaaccg gcagaagcac cgaaagcagc agttgaagac gcacaaccta aaggagcact
    10441 tccagaagga actgtggtcg gagacggaaa aatcaaatat gtattagcac gtgttgactc
    10501 acgtctgtta catggacaag ttgcgacagc ttggacaaaa gcagtgcaac caaaccgtat
    10561 tatcgttgtt tcagatgcag tatcaaagga tgatctgcgt aagagactaa tcgaacaagc
    10621 tgctcctcca ggtgtaaaag caaatgttat tcctattagc aaaatgatcg aagtagcaaa
    10681 agaccctcgt tttggaaata ccaaagcatt gcttttattt gaaaatcctg aagacgtatt
    10741 gacagctgtt gaaggtggcg tagacatcaa agaattaaat gttgggtcaa tggcgcattc
    10801 ggtcggtaaa gtcgttgtaa gtaaagtatt gtctatggga caagaagacg ttgaagcgtt
    10861 tgagaagctt gaacaaaaag gtgtgaaatt cgatgtacgt aaagtaccta atgattcacg
    10921 cgataacatg gatgatattt tgaaaaaagc aaaagctgaa ttagcaaaag cgtaataaat
    10981 aatattaaaa tttataggag gcttatcatg tctattattt caataatttt agtcgtatta
    11041 gttgcctttc tagctggtat ggaaggtatt cttgatgaat ttcaatttca tcaaccacta
    11101 gtggcatgta cattgatcgg tttagttacc ggtaacctcg aagctggtat cgtacttggc
    11161 ggtacgcttc agatgatcgc tttaggttgg gcaaatatcg gtgccgctgt agcaccagat
    11221 gctgcattag catcagtagc atcagcaatt attttagttt taggtggaca aggtgttaaa
    11281 ggtgttcctt ctgcgatcgc gattgccgtt cctttggctg ttgcagggtt gttcttaaca
    11341 atgatcgtac gtacaatcgc tgttccaatc gttcatttga tggatgcggc tgctgaagaa
    11401 ggaaacatcc gtaaggttga aatgtggcac atcattgctg tatgtttaca aggggttcgt
    11461 atcgcggtcc cagcagcagc gttgctattt atcccagcac aaactgtgca atcattcctt
    11521 gaatcaatgc cagcatggtt aacagatggt atggctatcg gtgggggaat ggtcgtagct
    11581 gtaggttacg ctttggtaat caacatgatg gctacaaaag aagtatggcc attcttcgtt
    11641 attggtttcg ttgtagctgc aatttctcaa ttaacattga ttgctctagg tgctttaggt
    11701 gttgcattag ctcttattta cttgaacctt tctaaaatgg gtggttcatc aaataatgga
    11761 ggcggaagca actctggtga ccctttaggc gacattttga atgactatta atcttgaagg
    11821 aggaaaataa aatggcagaa gaaaaaatca aattatcaaa aaaagatcgt ttagctgttg
    11881 cgtggcgctc taccttcatt caaggttcat ggaactacga acgtatgcaa aacggtggct
    11941 gggcattttc tatgattcca gcaatcaaaa aattatacaa aacaaaagaa gaacgttctg
    12001 cagcattaaa acgtcacttg gaattcttta atacacaccc atacattgct tctccaattt
    12061 taggggttac attggctctg gaagaagaac gtgcgaatgg cgcgcctgtt gatgatgtag
    12121 cgattcaagg ggttaaagta ggtatgatgg gtcctttagc tggtgttggt gacccagtgt
    12181 tctggtttac agtacgtcca atgctaggtg cactaggtgc ttcattagct atgggaggaa
    12241 atatccttgg accaatcatc ttcttcttag gttggaacat tattcgttgg gcattcatgt
    12301 ggtatacaca agaatttggc tacaaagctg gttctaaaat tactgatgac ctttctggcg
    12361 gattgttaca agacgtaaca aaaggtgctt caattttagg gatgttcgta ttagctgccc
    12421 ttgtacaaag atgggtatca atcaaattct taccagttgt atcaactgta aaattagata
    12481 aaggtgctta catcgaatgg gataaattgc cttcaggtgg tgaaggaatc aagagtgcat
    12541 ttgaacaagt taataatggc ttagcccttt ctcctgaaaa ggtaacaaca ttacaagaca
    12601 acttagacca attgattcct ggtttagctg cattaggatt aacattgtta tgtatgtggt
    12661 tgcttaagaa aaaggtttct ccaatcgtta tcatccttgg tttattcgta gtcggtgttg
    12721 ttggacacgt catcggactt ttataatcca taaaaatata gctcgggcgt tgtcccgagc
    12781 tttttttata tagtatactg ttcataaaca aatatctgga gggagaaaat ggttcaatca
    12841 atcaatacaa aagtagactt ggtaattgat gctacttcgt ttacgggtct gacagattac
    12901 gggcaaatca tgataggtga taatggtttt gagttttacc atgcgcgaga tagacgcaaa
    12961 tatatccaaa ttccatggga agaagtggat tatgtactag catcagtcat gctaaaggga
    13021 aaatggattc ctcgatatgc cattcaaacg aaaaaaaatg gtacatacac attttcttcc
    13081 aaagaaccta aaaaagtgct tcgtgcgatc agagaatatg tagatgaaga tagaatggta
    13141 caatcattga gtttctttga tgtagtgaaa cgtggtattc gtagtatgtt taaacgcaag
    13201 taaaaaataa agaaaacttc taagaggagg ttttctttat ttttttactt tgcagaagaa
    13261 aatatgaaat agcaaaacca attatttgtc ccctttaaat cccatatgct aaaattgatt
    13321 agcaaagaag gaggttatat tatgagttgg ttatggacat tgattgttgg agccgtgatc
    13381 ggagcaattg caggtgcgat caccagtaaa ggaaattcga tgggctgtgt aacgaatatc
    13441 attgctggac tagtcggttc aagtattgga caagcgattt tcggcgaatg gggaccaaaa
    13501 gctgcaggta tggcacttat tccatctatt ttaggcgcag tgattttggt agcagttgtc
    13561 tcatttttct ttggaaaacg atcataagtt tttacaaaat agtaaactaa aaggagttgc
    13621 agcgagactg tgactccttt ttggctttat ttatttaaaa taaaaagaag ttttccggaa
    13681 atttttattt aactgtcgtg tacgaagaaa agtttgctat aatggaaaaa agcgtgcaaa
    13741 gaaagaggga gtttcattat gatgctacgt gtagaaaaat tgcgcaaaaa aatgcaagaa
    13801 gaaaatttgg attcattttt ggttaccagt ccgtacaatc ttcgttactt aacgaacttt
    13861 acaggtacga caggattagc tgttattact ttggaaaaag cattttttat tactgatttt
    13921 cgttataccg agcaggcggc agcgcaggct caagggtttg aaattattaa aaatgtcgga
    13981 cctatttttg atgaggtagc aaacttagta cgcaaagaag aactgcactc attagctttt
    14041 gaggaaacaa cagtctcatt tttagaatat tcggttttag aagaaatcat cgatgcggaa
    14101 ttagtacctg tttcacagat gatcgaagaa ctcagagaag tgaaagatga agaagaaatc
    14161 gctattatcg aaaaagcatg tcatattgcg gatatggcat atgatcacat cctgaaaatg
    14221 atccaaccgg gcatgactga gattgaagtc gcaaatcaac tagactttta tatgcgttct
    14281 cttggcgctt caggtgtttc ttttgatacg atcgttgcta gcggattgcg ttcggctatg
    14341 ccgcatggtg tagcaagcaa aaaaatcatc gaacaaggtg acttgatcac attggacttt
    14401 ggttgctatt acgaagggta cgtttccgat atgacacgta cattcgctat tggtgatcct
    14461 ggggaaaaat taaaagaaat ttatcaaata gtcttagatg ctcaattagc agttattgat
    14521 gctgcaaaac caggaatgac tggtgtccaa ttagatgcag ttgctagaga ttatatttca
    14581 aaacatggtt acggggaagc atttggacat tctacaggac atgggatcgg tttagagatc
    14641 cacgaaggac caaacgtttc ttctcgtgca gaaaagcaat ttgtaccagg aaatgtgatc
    14701 actgatgaac cagggatcta cttaccagga atcggtggag tacgtattga ggatgacttg
    14761 ttgatcacag aagatggaaa tcgtgtgttg actcgttcac caaaagaatt gatcatctta
    14821 tagtttcatc aatagaagaa gtaagcgtaa aaatcagtgt tcacagactt tgttatagaa
    14881 aatcactcga tttaatgata cactatagaa gaacttttaa gctgtaagag ataataaagt
    14941 tgggtgtttt ctccaattca tagcagtttg cagctgatcg gcggcagttt tcttaccacg
    15001 tgatcactat gccgcatcat agagaattcg gatgtatctc gtgcttaggc aaagggagga
    15061 ataaataaat ggcagatgaa aaaaatttga ttttaaacgc aaaccaagat ttaggagaga
    15121 tcgtgatcgc tcctgaagtc atcgaagtaa ttatcgggat tgcagcttct aaagtagaag
    15181 gcgtatacgg aatgcgcgga acttttgcca gcaatgtcac tgaattatta ggacgtgcag
    15241 ctcacggaaa aggtgtttac ttagcaaacg aggaagatgg cttgaaagta gatctttact
    15301 gttatctaga atatggtgtt tcagttccta aagtagcaat ggaaatgcag gaacgggtca
    15361 gccagcaagt ccttttcatg acggatatcg atttatctga agtcaatatc catgtagtag
    15421 ctgttgttcc tgaaaaatta gaacaaccaa caatcgaaga actttttgaa gacgaagagg
    15481 aagagaatga ataaagaatt atcaagacac gagattcggg aaatggcatt gcaggcttta
    15541 tttccattag acttcaatgc agacctaaca aaagaagatg cgattttcaa cgcaatcgaa
    15601 ttagaccacc gcgacatgat caacgaagat gaatcagagt ttgttcctgt ttatcttgat
    15661 acgctagttg gcggtgtctg tgcaaaaaaa gatgaattgg ataaagtgat tgaaaaacat
    15721 ttaaaaaaca attggcacat caatcggatc tcaaaaatgg atttggtgat cttgcgtatc
    15781 gcgatttttg aaatgactta tgtgacagat gtaccagcgg ctgttgcttt aaatgaagca
    15841 atcgagttgg caaaaacatt tagtgatgac cgttcacgta aattcgtcaa cggtgtttta
    15901 tccaatgtat tgaaagaatt agaagctggg gcgtaagtcc tagctttttt ctatgaatca
    15961 tcataaacct gttataaatc gggaaaattc tatggtagaa tgaaaacaca aaaaatatct
    16021 gggagtggtt agatggcaga attgattaac ggaaaagaat tagctgaaaa aatgcaggca
    16081 gagattgctg aaaaaatcca aaaattgaaa gataatggta tccatcccgg attagtcgtt
    16141 ttattggtag gggaaaatcc agccagccaa atctatgtaa gaaataaaga acgtgtagca
    16201 aaagaaatcg gaatccattc attggtagag cgttatcctg agacgatttc tgaagacgaa
    16261 ctacttgcag aaattgaaaa atacaatcaa gatcctagtt ttcatggtat attggtccaa
    16321 ttaccattgc caaagcatat agatgaagaa aagatcctgt tagctatccg ccctgaaaaa
    16381 gacgtagacg gttttcatcc gatgaattta ggcagactcc ttgcgggtaa accggacaag
    16441 attccttgta ctccatacgg catcatgaaa atgtttgaag cttattctat cgatccggcg
    16501 ggtaaacgag cagtagttat cggacgaagc aatatcgtcg gtaaaccgat ggctcagcta
    16561 ctcttgatgg cagatgcaac tgttactgtt gctcattcta aaaccgaaaa tctggctgaa
    16621 ctggcacaag aagcagatat tttagtcgta gcaataggac gtggacattt tgtcacaaaa
    16681 gaattcgtaa aaccaggtgc tgtagtgata gatgtaggga tgaatcgtga tgctaacggt
    16741 aagctgatcg gtgatgtgaa atttgatgaa gtggagccta ttgcaggctg gatcactcct
    16801 gtgccaaagg gtgtagggcc aatgactatc acgatgctga tgtatcaaac cgtaaaatct
    16861 gccgaagctt ttggagcagg tgaatagatg gcacaagaat atttaactgt cactacatta
    16921 acgaagtatt tgaaaagaaa atttgatgcc gatccttatt tagaacgcgt atatttaaca
    16981 ggcgaaatat cgaatttccg tttacgtgcc aatgcccatc aatatttcag cttaaaagat
    17041 gaccatgcaa aaatatctgc tattatgttc aaaggagcat tccaaaaatt acgattccag
    17101 ccaaaagaag gaatgaaagt ccttgtcgtt gggcgtattt cattatatga agcgggaggt
    17161 tcttatcaaa tctatgtaga gcacatggag cctgatggaa taggtgcttt atatcaagaa
    17221 ttggaagaac gaaaagaaaa gctgatgaag gaaggccttt ttcaagggcc taaaaaaatg
    17281 ctgccacgtt tcccaaagcg aatcgcggtc cttaccagtc caagcggagc ggttatccgc
    17341 gatatcatca cgacggtgaa aagaagatat ccaattgtcc aattggtttt gttcccaaca
    17401 gttgtacaag gaaaccaagc agcggacaat gttgtcagga atatccagag agtagaagag
    17461 atgggcaatt tcgatacaat gatcatcggt cgtgggggtg gttcgattga ggatttatgg
    17521 ccgtttaatg aagagcgggt tgctcgggcg atttatcaag ctaatacgcc ggtgatttca
    17581 tctgtaggac atgaaacaga taccacgatc gctgatttag tagcagatgt tcgggctgcc
    17641 actccaacag cagctgcaga attagctgtt cctgttttgt cagaagagtt gatgcgcatt
    17701 caagaacggc aagctagatt gcagcaggcg tttgtacgcc agatccagcg caaacaagaa
    17761 cggttcgagc gtgctcgacg ttcctatgta tttcggcagc ctgaaagatt gtatgaaggt
    17821 cagaccatca aattagacca gttgaaacag cgattatatc aagctacaca gcaaatttat
    17881 catgcgaaag aaaaacaaac gatcgcatta agccaccaat tggaacaagt ggctccgctt
    17941 tatcgagtta aagcagctcg ccaagaaact gcttatctag aaaaacgctt agaagagaaa
    18001 atccaacaat atatgaaaca acagcagcag cgttttgctc aagctgttca atctcttgat
    18061 ttgttgagtc cattgaaaat catgggaaga ggctacagct atacgacgtt aaatgatcaa
    18121 gtagtaaaaa gtgtcaccga gattcatcaa ggggatttgc tgacgatcca ttatcaagat
    18181 ggaatcgtta aaggacaagt acaagagata gacaaaggag aataaaaata tggaaaatcc
    18241 aacttttgaa gagtcactgc aagaattaga aaaaattgtc atgcagttag aacaaggaga
    18301 cgttccatta gaatcagctc tagattcgtt taaacgagga atggaattaa gcaaacattg
    18361 ccaagataca ttagctaaag cagaagagac cttgacgaaa atgatgacag aatcaaatga
    18421 agaagttgat tttgacggaa acgaggaaag ctgagatgag attaactgac ttttcagcta
    18481 ttcatctacc tgctgtagaa aaagaaatct tgtctttttt agatgagcat acaacggata
    18541 gaggactcta tgatgcgatg agttattcag tgaaagcagg cgggaaaaga atacgtccct
    18601 tattactttt aacggccgtt gcttcctttg atgagcctat tgatgttccc gtctatcaag
    18661 tagcagctgc tttagaaatg gtgcatacgt attccttgat ccacgatgat ttgcctgcga
    18721 tggacaatga tgatcttcgt agaggaaaac ctaccaatca taaagtattc ggcgaagcat
    18781 tagctatatt ggccggagat ggtttgctta caggagcatt ccagctaatc agtatggcac
    18841 acttaggtaa ttctcctaag cttctgctgc ttcagcaatt agctgtttgt gcgggatcac
    18901 aaggtatggt tgctgggcaa gctgcagata tcgagggcga atcgaaaaag ctttctttag
    18961 aagaattagc atttattcat gaaagaaaga cagggcattt gattcgttat gccttgctgg
    19021 ctggtggcat attagcgaag caacctgaag aaatcttatt gctacttcaa cgattagccg
    19081 aacatttagg tttagctttt cagataagag atgatctact cgatgtgatt ggtacaacga
    19141 aaacattagg gaaaacagct ggtaaagatg aacgtatgga aaaaaatact tacccgcgtt
    19201 tattaggcct agaaaagaca cgtgaggcgt tggagattga gctgttatcc gccaacaaga
    19261 tcatagacaa attagaagag gacgtttttt cttttgatgg cgggctgatg cgccagatga
    19321 tcaagcaatt tgatgtggag aaatgaggga aagaatggaa aaagaacgcg tagatgtatt
    19381 agcggtcaaa caaggattat ttgaaacaag agaacaagcc aaacgttcag tgatggctgg
    19441 tttgatttac aacgaaaaaa acgagcggtt tgataaaccg ggagaaaaaa ttccagtgag
    19501 tagtgaatta agagtcaaag gtaaaaaact tccttatgtt tctcgagggg gattaaaatt
    19561 agaaaaagca ctcaaagcat ttgatctatc tgttgaagga aaaacattgt tagatattgg
    19621 tgcatccact ggcggattta ctgatgcagc tttgcaaaat ggcgcaaaaa tgagttatgc
    19681 tttagacgtt ggctacaatc agctagcttg gaaaataaga caagatccta gagtcgtcgt
    19741 aatggaaaga gtgaattttc gttatgcaaa acccgaagac tttaccttag gaattccaga
    19801 agttgctgtt atcgatgttt cttttatttc actaaaactg atgctgcctc cattacatgc
    19861 tattttaaaa gaagagggag aagtgattgc tttaatcaaa ccccaattcg aagcaggcag
    19921 agaagctgta gggaaaaacg gaattgttcg tgaccctcag acccatcaaa aagttttaga
    19981 agacattttg tcatttgcgg cacaaggtgg atatgatgtg ctggaattaa gttattctcc
    20041 gatcacgggg ggagaaggaa atatcgagtt cttggctcac ttgaggaaag tacccgaaag
    20101 cggaacaatc aattcagcta ttaatatggc agaagtggtt tcaaatgcac acgaacagtt
    20161 tgaccataaa taaattgtaa ctgtgaaaat caagtgagaa gtatgcggat tcttctttat
    20221 tataccaagg aaataagcta tcattgatta agaagaatat gctaaggagc gaagacgtaa
    20281 tgagaaaaaa agatcggcat cgtttgatta ctcgattgtt gagtgagcaa gatatccgaa
    20341 agcaggaaga atttgttgaa atcctgaaaa gcaaaggaat atctgttact caagctacga
    20401 tttccagaga tataaaggaa ctgaaactga tcaaggtacc ggcttcagat ggcggctacc
    20461 gttatagcat accagctgaa acaaacgaag atgtaaatac taaattggaa aaactattaa
    20521 aagacgcttt cgtggcagtt gaccaaatgg aaaaatttgt tattttgaaa acattgccgg
    20581 gaaatgcttc ggcagcagca aatttgattg ataaacgtta caagaaagaa ttattttcga
    20641 ttatcaatga tgacgataat gttttgatga ttacacgaac tgaagaccag gcagttttat
    20701 tgaagaaaga cttcctgcat tacctttaag ttgaggagcg aatgtgatgc tacaagaaat
    20761 cagtattact aactttgcga ttattccgga attgcggctt tcttttcacg aaggaatgac
    20821 cgcgctgacc ggagagactg gtgcgggtaa atccattatt atcgatgctt taggtctgtt
    20881 agcaggagga agaggttcaa gcgattatat acgtcaagga gcagaaaaat gtgtgcttga
    20941 agggttgttt gaactaccaa aacaagaagg attctctgaa ctgatggttg aattagggat
    21001 cgaaacagat gaggacaatc tgattgttcg acgggatatg tccttaactg gaaaaaatgt
    21061 ttgtcgagtg aatggtcata ttatcacatt agctaatctg agaagaatcg gcagttattt
    21121 agtagatatc caaggacaaa acgaacatca ggaactgctc cagcctgaat cacatcttgc
    21181 tttattggat cgttttggag atgtagcttt ccaacagaag aaaaagagtt atcagcaaga
    21241 atatatctct tatcgtgagc tggaaaaaag ggtacgaaaa gtgcagcaaa atgaaaaatc
    21301 ctatgttcag agaatagata tgctccattt ccagcaagaa gaaatagctg ctgctgattt
    21361 gcaagtcgga gaagaagaga aattaaaaga agaaagagaa aaacttagca attatcaaaa
    21421 aattgctgat ggattagctg caggttacgg agcactgacg aataatgaac aaaacagtgt
    21481 agatggtgtt ggcttggccg tttcagaact gcaagggatc gcccatctag atgtggagta
    21541 tgaagcaatt tatgaaaata tccaaagtgc ttactatttg ctgcaagatg caatcggcga
    21601 tatgagtcgt cagattgatt tattggagtt agatgagagt cgtttagaag aagttacgca
    21661 acgtttagaa ttaatccgac agttgaaacg taaatacggc gaatccattg agtcaatatt
    21721 ggcttactat gacgaaatca ccgaagagct agcttcttct gatttttcag aaggtcaatt
    21781 ggacaaaatg aaagaggaac tagagcaaaa agagcttcta cttcagcaac aagccgcaga
    21841 tcttcatgaa gcgcgtaaaa aaatcgcaaa agaattggaa aaatccattc tgcatgaatt
    21901 gaaaagtctg tatatggaaa acactgagtt tgaggtacgt ttcttaaaag aagaaaatag
    21961 acaattgaat catgatggat ttgaccaaat cgaattttac attacgacca atccaggaga
    22021 gccactgaag cctttggtga aagtcgcttc tggtggcgaa ctgtctcgga tgttgcttgc
    22081 tttgaaaact attttttctt ctgagcaagg tgtgacaagt attatttttg atgaagtgga
    22141 tacaggtgtg agcggaagag ttgcacaggc catcgcagat aaaatttctc aaatatcgaa
    22201 atactctcaa gttttgtgca tcactcatct gcctcaagtt gctgcagtcg ccgactatca
    22261 atattatatt gtgaaagcag tgattgatgg acgtacgcaa acttctgttt cagagttgaa
    22321 aacaaaagaa agagaagaag aaattgcacg tatgctggct ggaagtgaga ttacaaaact
    22381 cacactcgaa catgcaaaag aactattgaa actcgcaaaa aggacctgag ccacctcgca
    22441 gtggttcagg tccttttcag cagctgatag ctatatttta tttttacatg acactcatta
    22501 cagcagtcaa tacaacagat ccaatcgtta aaatcagcat tgtccaaatg acaaattttg
    22561 ttactttagc aaaagtactt gtttgttttt tttcacgcat tgttttcaac ctcgtcatta
    22621 attagttgat tcaagtgtac aatctttttt ccatttccac aagagggctt ttttataaaa
    22681 acttcccttt ttttaaataa taggtagtta cgatacaaat aaataatgtt aatagaacta
    22741 gccatataaa ggcatcatcc ctttcagcaa taggtaactt aatgttcatt ccatagatac
    22801 tgccgacgat tgtcggtata gttaaaataa tcgttaaaga agttaaaatt ttcataatat
    22861 tattcagatt attcgatacg attgctgaaa aagtctgatt catttgttct actagtttta
    22921 attgaatgcg agaagtagtc attgcctgct ctgtttccac caatacatca cgtaaatgat
    22981 ttttcaaagc atgattttct tggaaaagtt tattttgcgc tagttctttc aatgcatcta
    23041 aattagcaga agtcgcttct ctgaaataaa cgaggctttt ttggatatcc atgatttgat
    23101 aaagttgttt gttttcagtg gatacttgaa gtttggcttc caaagtatcg cattgagatt
    23161 gaagcgtagc taaataactg ttgtaagaga gtgtgacctg ccaaatgaat tgaaagaaga
    23221 tattgagatt aggcgaaata tcactttttg gaaaggtctg gctaaagact ttctttaaaa
    23281 acagtggttc atgattcgta attgtgataa gcttcttttt gggcgtcaaa ataatagaga
    23341 gcgggtatgt atccacttga aaataaccgc taggacttgt tttagcaaaa ggatattgta
    23401 acaataataa cgctggcttt gtcaactttg attgattgaa ttcttctgta cgggaatttt
    23461 ctgcatcgtc caatatggaa gtgatgtaat ctgacggaat ttcaaattga tgtgtcagct
    23521 gatgaatctc ttcttgatta ggacgttcta cacaatacca gatcgtttgg tcagtttcct
    23581 ttccggtatt acgcagtttc tcattatcta atgtaaaata tttgatcatg attttcctcc
    23641 tgttgcctgt ttcttttatt ataacggata gggaattgga atacatggaa tgtgtttgta
    23701 agatatagaa tataactgca taaatttaaa taaaatgaaa cagttgtgta aagtatatac
    23761 agtatacttg aagcaacgat aaaaaaggag tttacgttca tgggcacatt cacaccactt
    23821 atcttgtttt ggtatattta cccggtaatc gttttgtttg gttgccaatt tcttgtaaaa
    23881 ttattttcgt taaatcgtcg ttttaaaata aaagcccctg atttggcgat tccttttttg
    23941 tggggcggta tgcatgcatt gtctagaaat acagggacaa tttctatctt accgtttttc
    24001 tttatttctg ttttgctaat gggaatttgt attgctgttt tccaagcata ttattatgaa
    24061 gaaattattt atccgcgtta tttcaagatg acttggcgtt tggtttttct gttgacaatc
    24121 gtcttgtacg ctgtcttgat cattgtgaac atactttctt acctatgaaa aaaatagaaa
    24181 agctgtaaaa agtcttttaa aaggcttttt gcagcttgat ttttaaaaaa atgtttatga
    24241 ataaaaaaag ttgttcccgg atttcccaga aaaggtggta gaaagtgggg gattgtggta
    24301 gactaatttt agttagtgga ggaatggggg gctttcaatg ttgatgggtg aattccaaca
    24361 taatattgat gcaaaaggac gtttaatcgt gccctcaaaa cttcgtgaag aacttggcga
    24421 aaagtttgtt ctgacacgcg gattggatgg ctgtcttttc ggctatccga tgagcgaatg
    24481 ggaaaatctg gaagctaaac tgaacgaaat gccgttggct aaaaaagacg cacgtacttt
    24541 tgtgcgattc ttctattcgg ctgccactga atgcgaactt gataaacaag gacgaatcaa
    24601 tatacccagc acgttaagaa attatgcagc tttgacaaaa ggttgcgtag tcatcggtgt
    24661 atctaaccga attgaaattt gggatgagac acgatggcaa gatttttctg cagcagcaga
    24721 agagaacttt gacgaaattg ctgaaagtat gattgatttc ggactataag aataggaaga
    24781 ggctgactaa tgactgaaac atttcaacac tatacagtca tgttgaaaga aacggtagat
    24841 ggattgaaca tcaaaccgga tggcgtttat gtagactgta cactcggcgg tgccggacat
    24901 agtgaatatt tattaagcca actaagttct aaagggcatc tgtatgcgtt tgaccaagat
    24961 caaaaagcaa tcgatcacgc caagctgcgt ttagcttctt atgtcgaaca aggtatggtc
    25021 acatttatca aagcgaactt cagagaatta gaagaacgct tgagtgagca tgtagataag
    25081 gtagacggca ttttgtatga tctaggggtt tcctctcctc agctagatga agcagaacgt
    25141 ggatttagtt atcatcaaga tgcaccgttg gatatgcgca tggatcagtc agctccttta
    25201 tccgcttatc acgtaattaa tgaatattcc taccatgaat tagtaaagat tttcttccgc
    25261 tatggcgagg agaaattttc caaacaaatt gctcgtgaaa tcgaacgagt acgaaaaaca
    25321 aaaccaatcc aaacaactgg tgagcttgtc gaaatcatta aacaagtcat cccagctccc
    25381 gcaagaagaa aaggcgggca tcctgcaaaa agaatttttc aagctgtgcg gattgcagta
    25441 aatgacgaac tcggtgccga agaggcctct ttagaacagg caatccggtt attgaaagtc
    25501 aatggaagaa tcagcgtaat cacattccat tcattggaag acagaattgt caaaagtatg
    25561 tttaaagaat atagtacggt acaagatcta ccaccgggac ttcctgtcat acctgacgaa
    25621 ttccaaccag aactgaaagt cattactcgt aaaccaatcc ttccttcaga ggaagagcta
    25681 acagaaaaca atcgatcacg cagtgcaaag ttacgtattg cagaaaaaat aagaatgaaa
    25741 gaggagtaga atgatggcag aattaaagaa aatgcaagat tacgaatatg atttacctga
    25801 attggtggat cagccggaac aacaaatgcc tgattcttct tcgaatcaag aaatcattct
    25861 tccacaatca ccggcaaaac gattaaagca gatttctgct ttggaaaaaa ttgctgtggc
    25921 aagcgtggcg attgctattg ttgctttatg tgttttaaca gttatgctgc gcacaaatat
    25981 cagcggagct gaaaaagaaa tcacgtcaat acaaacagaa atcaatgata aaaagcaaga
    26041 aaaaacgagt ttagaacaag aaaaaaacga actttctcgt actgaacgga ttaaacaaat
    26101 cgcagaagaa aaaggattgt ctattaatga cgacaattta aggaaagtga agtaaatgag
    26161 tcttaaaaat aaaattcggc ggtttatgga aaagaaaaat ctaaatccga tgaacaatcg
    26221 caaaaaagta ggtatcattt tatttgctac gagtattgga ttgttctttt tatttgccgt
    26281 ccgtttctcg tatatcgtta ttggaggtca tgttgctggt acctcattag ctgaaaaaac
    26341 aaaacagttg taccaaggaa gtgaagtagt aaaagcaaaa agaggaacga tttatgatcg
    26401 taacggtgtg gcgctcgcag aagatgcctc ctcttattca attaaagcga tactctcaaa
    26461 aacatatacc tctggggata aaaaactgta tgttgaagaa aagaattttg ataaaatagc
    26521 agaaatcctg cataagaatc tttctataga caaaaaagat gcactgaata ttttagagga
    26581 cggcgcaaaa aaagagctgt atcaagttga atttggtagc tatgggaaaa atatctccca
    26641 agaaaccaag caaaacatcg aagcggacat gaaaaaagaa ggtgtcgctg gtctttattt
    26701 tgtcgaccat caggctcgga tgtatccaaa tggcgtcttt tcttctcatt ttattggata
    26761 cgcagttcca gacaaagatg agaatggctt agttggtaaa ctaggtttgg agtctgctta
    26821 caatgatatc ttgagcggta aagatggtaa gattatttat caaaaagata attttcaaaa
    26881 tcctctgcca ggtacagtgg cagaagaaga aaaagctgtc gacggacaag atatctacac
    26941 gactttagac agcagactac aaagttattt agaaacactg atggatcaag taaatgaaga
    27001 atatcagcca gaagaattga cagcagtcct gatgaaagca aaaaccggag aaatcttggc
    27061 aatgggacaa cgacctactt tcaatcctga aacaatggaa ggattgactg gaaaagatgc
    27121 tatctggcgt aatttcttgg tacaagatag ttatgaacca ggatcaacca tgaaagtttt
    27181 cactactgca gctgctatcg aagaaggaga attcaacgag aatgaaacct tccaatctgg
    27241 aaaaatccaa gtagaagatg ctacgatcaa tgaccatgac tttggtgaaa aaggtgtgct
    27301 gaccatgcgt caagctcttt catggtcaag taacgtcggg atggtcatac tggaacagcg
    27361 attaggcgga cgatggtata actatttaca aaaactggga tttggacaaa gtactcattc
    27421 tggattagat gatgaagtaa acggtgcttt acctacatta aatattgtcg accgagcaat
    27481 gagtgcttat ggacaagcgg taggtgtgac gaatttccaa atgatgaaag ctttcacttc
    27541 tattgcgaat aacggtacaa tgattcaacc tcgatatatc agcaaagtgg tggatcccca
    27601 aactggagaa gagcgaacaa ctcaaacaga agttctaggg caaccttttt caaaagaaac
    27661 aacagaaaaa gtccgtgaat atatgagaga tgttgtcgaa agcgaaaact acggtagtac
    27721 ttatggtgta tatagtgtac ctggatacaa tgtatcggca aaaaccggaa cagcccaaat
    27781 cgcttctgat acagggggat atcaaacagg agatacagcc tacctgtatt cgattgtgga
    27841 gatggttcct tctgaagatc cagactatgt cttgtatcta acaatgaaac accctaagac
    27901 atatgatcga atggcattgg ctaaaatcgc aaatccattg atgaaacggg caatggattt
    27961 taaagaaact gaagaagatt cagatacaga aacaaaaaca gaaaaagtat ccgtagccga
    28021 ttatcgtaat cttgaagcgg acgttgcagc agctgatgct caaaaaagtg gactgcaacc
    28081 tgtagtgatc ggtaatggta aaaaagtaca aaaacaatct actgccaacg gtgatcagtt
    28141 gatctctgga gaaaaactga tcctatatac tggtggtgat aagctgatgc ctgacgtaac
    28201 aggatggtca aaagcagata tcatgaagct ggggaaaatc ctcggtattg aagttagttt
    28261 tgatggagat ggttattgtg tcaaacaaga acttgctcca tatgaaaaaa tcactgaaga
    28321 caaacttagt tttactttag aagaataaga agagaaatag gagagaaaag agcatggaat
    28381 ggacacaagc attgattccc attgtcagca gttgtgcaat gacaattgcc gcaatgccgc
    28441 tatttattgg ttattttcaa atgaaaaagc aaggtcaggc gattcgtgag gagggaccaa
    28501 agtggcacaa tagcaaagcc ggaactccta caatgggcgg cttagtgttt ctgatcggct
    28561 ctattttgac aggaatttgg gttggagctt ggcaaaaaca gctaactcct actcttttca
    28621 tcttgctttt tgtattagcg ttatacggag taatcggctt tcttgatgat tttataaaaa
    28681 tattcaagaa aagaaacatg ggactgaact cgaagcagaa attgattgga cagattctag
    28741 ggggaatcat cttttatctt gtttaccgtt ctgaaggtta tccaggtgta ttgaatttct
    28801 tcggactaga tctaccttta ggaatcattt atggtatttt cgctctcttc tggcttgttg
    28861 gattttcaaa tgcagtaaat ctgacagatg gcatcgatgg attagttgct ggcttaggaa
    28921 gtatctcttt tgcagcttac ggtctaattg cttggcatca gcatcagtat gatgtattaa
    28981 tcatttgctt aagtgtttta ggaggtttac tgggtttctt cgtctacaac agaaaacctg
    29041 ccaagatttt tatgggagat gtcggttcat tagcgttggg cggactttta gcggcaattt
    29101 ctataatgct aaaccaagaa tggacattgc ttttgattgg tttgatctat gttatggaaa
    29161 cagcaagtgt gatgcttcaa gttacttcct ttaagcttac aggaaaacga atttttaaaa
    29221 tgtctccaat tcatcatcac tttgaaatgt gcggatggtc ggagtggaag attgatacag
    29281 ttttttggtt gatcagcatt gtgacttcgt tgatcacatt atggatcgtt tggtaggaga
    29341 tgacgggaaa tgaaaaaaat atcaacatat gaaaataaga aagtgcttgt cttaggactc
    29401 gcaaaaagcg gagtaagtgc ggccaaatta ttacatgaat tgggcgcact tgtcaccgtt
    29461 aatgatggaa aaccttttga cgaaaatccg gaagcacaag agctgctttc tttagggata
    29521 aaagtaataa caggtagtca tccaatcgaa ttgttggatg aagaattttc attgatggtc
    29581 aaaaatccag ggattcccta cagtcatcct ttagtagcaa aagcccaaga aatgggtatt
    29641 ccggtaatta cggaagttga gctagcttac gaagtagcgg aatgcccaat tattgggatt
    29701 acaggaacga acggaaaaac aacgacaaca acgatgacag gactactact gaatgcagga
    29761 gcagatcaag gaattgcacg tttagcgggt aatattgggt atccagcaag tggtgtagcg
    29821 caagaagcaa aatcagaaga taaaattgtg atggaattgt ctagcttcca actcatggga
    29881 atcacagatt tccgccctca tatagcggtg attaccaata tctatgaagc acatattgat
    29941 tatcatggta caagaaaaga atatgtcaaa gctaaatgga accttcaaaa aaacatgaca
    30001 gaaaaagatt atctgatcct taactggaat cagtcagaac tacaagaatt agcgcaaaga
    30061 acaaaagcac gcgtactgcc tttctcgaca aaagaagtgt tggaagacgg tgtgtatgct
    30121 gacgattact caatatacta taaaaaagaa aaaataatgg aaatatctga acttggcgta
    30181 ccaggtaagc ataatgtaga aaatgcacta gctgctattt ctgtagcaaa attgtatggt
    30241 atatcaaatg aagctatacg agaaacgttg cattttttcc atggcgtacc acatcgtacg
    30301 caatatgtag gagaaatcca aggcagaaaa ttttataatg attcaaaagc aaccaatatt
    30361 ttagcgacta aaatggctct aagtggattt gaaacgtcta aggtcgtgtt attggctggc
    30421 ggattagaca gaggaaatac atttgatgaa ttaattcctt cattaaaagg aatcaaagca
    30481 atggtcgtat ttggccaaac aaaagaaaag ttgatggatg ctggaaaaaa agcaggcatc
    30541 gagacaatag taacagccga ttctgtagaa caagcagttc ctttagcatt agaaaacagt
    30601 acagatggtg atgtagtttt attatcacca gcgaatgcca gctgggatca atacccaaat
    30661 tttgaaacta gaggaaacag attcatggaa gctgtgaacc gattaaaata gaaaaagtag
    30721 aagcgagcga taaaaaatga aaattttggt tacaggcgga ggaacagggg gacatattta
    30781 tccagctctt gcctttgtca attatgtaaa gactcaagaa ccgaatgctg aattcatgta
    30841 tgtgggagca aaacgaggtc tagaaaacaa aatcgtccct gatacaggaa tgcctttcca
    30901 taccttggag attcaaggat ttaaacgaaa aatttccatg cataacatca agacggtccg
    30961 attgtttctt aagagtatcc gtcaagcaaa aaaaatcctc agtgattttc aaccagatat
    31021 cgttatcggt actggaggat atgtttccgg agcggtagtg tacgctgcag ccaaaatggg
    31081 tattccaaca gttatccatg aacaaaacag tgtaccaggt gttaccaata aatttttaag
    31141 ccgatatgtg gatcggatcg ctctttcatt taaagatgcg gcttcctttt ttcctgaaaa
    31201 caaagcagtt cttgtaggta atcctcgagc acaagaagta gcagatacta aaaaatcaga
    31261 tattttgaaa acatttgatt tggatccaga aaagaaaaca gtcttgattt ttggcggtag
    31321 tcaaggagca cttaaaatca atcaagcagt atcagttttt ttaagtgaat atattccttc
    31381 ttcttaccaa gttttgtatg cttcaggaga tagatattat gaagagatcc taaataaaat
    31441 aaatcctgaa atacaaaata ttagtgtcca gccttatatc aaaaatatgg cagaggtcat
    31501 ggcttccagt gatctgctgg tggggcgtgc tggtgcaact tcgatcgcag aattcacagc
    31561 tctggggtta ccggcagtgt tggttcccag cccatatgtt acgaatgatc atcagactaa
    31621 aaatgcaatg agtcttgttc acgcaggagc agcaaaaatg attgcagata atgaactaac
    31681 aggtgaatca ctaagtcaga cagtcaacga aatcatgggt gatgaagaat tgcaaaagca
    31741 aatgtgccga gcttctaaag aacaaggaat ccctgatgct tcaaaacgtc tttatgactt
    31801 agtaaaacaa ataatcaaaa aataaaggcg gtggtcttag tgagtaagaa aaaagaacca
    31861 aaaaaattgt ctcatccgtc ttctgatgaa aacaatttga ctccttggca aaaggctaac
    31921 cgaaaatatc tggcagaaca agagatgaaa aaccaagagc caaaaaaaga agacataaca
    31981 ttagatacac ccctttcaga ttctgaagaa gaaaaaacgg ttcaagagga acagcaagaa
    32041 gaaagccagt ccgagaaaaa aatcgaattt tttgaagaga tcaagcaaaa gaaaaacggt
    32101 ggaccatata acggttcttt tttgaaccgg ctgcccaatt taaaaagtca acggcacaaa
    32161 gtactatttc gtcggttagc tttgatcatc actgtattgg gtataccgct gatttttttg
    32221 atctattatg tttctcctta tagcaaatta caagcagttg cagtatcagg caataagaca
    32281 gtcaacagcc aagaaatcat ctctgataca aaattgtcat taggagaaaa tgtttgggga
    32341 cagtattttc atcgatctac ttatatcgat cgccttaaaa aagcacagcc aagaatcgaa
    32401 acagcaaata tacatttcaa agggatgaat gaattcgatt tggatgtaac agaatataaa
    32461 gagattgctt tgatcgcaaa aaacaatcaa tactacccag tgattgaaaa tggaacagta
    32521 ttagatgaaa aagtagcaaa tcctacaaaa aatctcccta tcttggaaga gttcaaagac
    32581 tctgcaaaaa tcaaagaatt aacaaagcaa tacaatcagt tatcatcaga attacaaaaa
    32641 gcaatttctg aaatcaagta cacgccaaga gcaagcaata aaaatctgat ccaattgaat
    32701 atgaatgacg gcaatcaagt tattgtaaat atcaataatc ttgcgaacca aatgaaatat
    32761 tattcgcaag tagccaaaga tatggatgaa aaaggtgtga tcgacatgga agttggtatc
    32821 ttctcgcatc cttacggtag cactcaagaa acggaagaat cgggccaatc ggaagaaaca
    32881 actgaaagtg aagaaaatgc ggatcaaaca aacgaatcaa gtgaagaggc agaaacgcaa
    32941 aaagcacaaa cacctggatc gtctagcaca aacggatcat ctgattcaaa tgattcaagt
    33001 gaaacaagtc aaatagaaga taatccaagt acaactccgt caagtttaaa tgaaaattga
    33061 taaaacaact ttaaaaagta agaatgtact ttctaaaaac cagtaattta tggtagaatt
    33121 ggaagcagtg aatatatcta ttaataagta tattttaaaa cggacgctag ttgttcgctt
    33181 gtatatggaa tagtaagtag gagggaatcc cattcatggc aaaaacagga atgtatgtag
    33241 gccttgatat tggaacgaca tctgttaaag ttgtcgtggc tgaatatatc gacagccaaa
    33301 tgaatattat tggagtagga aacgcaaaat cagaagggat taaccgaggc attatcgttg
    33361 atatcgataa aacggtccaa gcgatacaac gagcagtacg acaagcagaa gaaaaagcag
    33421 gtatccagat caaaggcgta agtgtcggtt tgccagcaaa catgcttgaa gtagaaaatt
    33481 gccagggaat gattgcagtt aacggagatt caaaggaaat caccgatgaa gatgtcagaa
    33541 atgtggcttc agctgccctt gttcgttcaa tacctcctga acgtcaaatc gtgtcaatat
    33601 tgccacaaga ttttactgtc gatgggttcg agggaatcaa agatcctcgt ggaatgatcg
    33661 gcgtaagatt agaaatgtac ggtctgttgt ttacaggacc taaaacgatc atccataaca
    33721 tacgtaaatg cgtggaaaat gccggattaa tcgtcaacga aatggtgatt actcctttag
    33781 cgctgactga atcaattctt tctgacggag aaaaagattt tggtacgatc gtcattgata
    33841 tgggtggcgg ccaaacaaca acggctgtta tgcatgataa gcaattgaag tttaccaatc
    33901 ttgaccaaga aggtggcgaa tttgtcacta aagatatctc tattgtatta aatacgtcat
    33961 ttaacaatgc agaagcgttg aaaataaact acggggatgc atacccagaa cggacatcac
    34021 cagatgaaga atttccagta gatgtgattg gtcagtcaga accagtgaaa gtcgatgaac
    34081 gctacttgtc agaaattatt tcagctcgaa tggaacagat tttcaacaaa gcaaaagatg
    34141 cattggacca aatcgaagca ttagagttgc caggtggcgt cgtattgaca ggcggagctg
    34201 ctagtcttcc tggtgttgtg gacttggcac aagaaatctt cggcgtaaat gtaaaattgt
    34261 atgttccaaa tcacatgggg ctgagaaacc cggtatttac aaatgtaata agtatcgtgg
    34321 attattcagc aaacttgagt gaagtgtatc aattggcaaa aattgctgtt acgggtgaaa
    34381 cctcagcagc tcgtcaaatg gtagttgaac aagaaacaac aaacacatat gagagctatg
    34441 aagcacctga agaaacaatc tacgatgagc cggaaccaaa agagtccgga gaaaatgtaa
    34501 aaaataaaat caagggtttc tttacaaata tttttgatta attcatcctg ggaggaataa
    34561 gatatggaat tctcaattga taataatatc aatgacggcg cagtaatcaa agtcatcgga
    34621 gtcggtggtg gcggtggaaa tgctgtaaac cgaatgattg aagaaaacgt taaaggtgtt
    34681 gaattcatta cagccaacac agacgtgcaa gcattaaaaa attcaaaagc tgaaacagtt
    34741 atccaattag gccccaaata tactcgtggt ttaggtgctg gttctcagcc agaagttgga
    34801 caaaaagcgg cagaagaaag tgaacaatcc ttacgcgaag ctttagacgg tgcagatatg
    34861 attttcatca ctgcaggaat gggtggagga accggtacag gtgctgcacc aatcgttgca
    34921 ggtatcgcga aagaattggg cgcattgact gttggtgtcg tgacacgtcc attcactttt
    34981 gaaggaccga aacgtggccg ttttgctgca gaaggtatcg ctcgtttgaa agaaaatgtg
    35041 gatacattat taattatctc aaataaccgt ttattagaag ttgtagataa aaagacaccg
    35101 atgcttgaag ctttccgtga agcagataat gttttacgac aaggtgtaca aggtatctct
    35161 gatttgatca cagcgccagg ttacgttaac cttgactttg ctgacgtgaa aacagtgatg
    35221 gaaaaccaag gtacagcatt gatggggatc ggtgtggcta gtggagaaga tcgcgtagta
    35281 gaagcaacga aaaaagcaat ctcctctcca ttgcttgaaa catctattga tggagctgaa
    35341 caagtacttc ttaacatcac aggcggtttg gatatgacat tgttcgaagc acaagatgct
    35401 tcagatatcg tagcaaatgc agcaactggc gatgtaaata tcattctagg tacatctatc
    35461 aatgaagaaa tgggcgatga aatccgtgtg acggtcatcg caacaggtat cgatgaatca
    35521 aaaaaggaac gcaagtctag ccgaccagct agacaagcac aaatgcaatc acctgctcaa
    35581 aagactgtat tagatatgga tcaagctaaa ccaacttctt cagaagaaga aaacagtttt
    35641 ggcgattggg atatcagacg tgaacaaaat gttcgtccta gagttgatga ttccaatttt
    35701 gacaatatcg aaaaaaaaga atttgataca ttcaaccgcg aagaaacaaa atctcatggc
    35761 gatgatgaat taaatacgcc accgtttttc cgtcgtaaaa aataaaggag aggaagagca
    35821 catgattgct gacaacttgc agaaaatcaa gcaagaaatt caggattcgt gtgctcttgt
    35881 tcatcgtgat ccgaaagaag ttacattagt agctgtaaca aaatctgttg aatccgctca
    35941 agctgaagaa ttggttagag ctggcgttat gaattgtgca gaaaaccgag tagataaatt
    36001 attagaaaag aaacaagatt tatttgattt tcctgaaata aagtggcatt taattggtaa
    36061 tttacagcgc agaaaggtaa aattgattgt aaatgaaatt gattactttc atgcgttgga
    36121 cagtttaaga ttagcagaag aaatccagaa gcggttagag aaagaattat cctgttttat
    36181 tgaagtaaat gtttctggtg aggaatcaaa acatggaatt tcaccagatg agcttttacc
    36241 gtttgtggaa tctttagctg cctgcacaaa aatcaaggtt gttgggttga tgactatggc
    36301 gcctaaagaa gcttctgatg agcaaatcca taaagtgttt ggtacgctga aagaattgcg
    36361 tgatcttgtt caagcaaaag gttatgccca tgcaccatgt agtgaattaa gtatggggat
    36421 gagtcaagac tttcaaattg cgattgaaga aggtgcaaca tttatccgtg taggaacagc
    36481 gctattcaaa gacgaataaa ggaggaacaa aaatgccgct tttaaacaga ggagcaattg
    36541 ctaatttttt cggattagct gatgaggaag agtacgaata ccaagattat cctgaaacaa
    36601 caaaaaaggc tgtacagcca actaaaaaaa atacaacaca gaatcaatca actcattctg
    36661 tatctgctgc gaatactcat gaaaaacaaa aaacggcgac ttcacgtcct gtaacgcatg
    36721 aaagtattca gccggctgaa aagaaaaaag taattgaact acatcaatca cctacaaaaa
    36781 ctgtagcgaa agaaagaaca gcttcaagaa cctctacaca acctaaagca aatcttgctg
    36841 gaaaaatcac tgtaatggaa ccaagagctt attctgaagc tatggcgatt gctaaacgaa
    36901 tcattgctgg agaagcaacc ttagtgaatt ttcatttagt agaagaaaaa caagcgagaa
    36961 gaatcgttga ttttctaaca ggaacagttt atgcactaga tggagatatc aaacgtgttg
    37021 gagatgagat ttttctttgt acaccgactg ggatggagat tgacagttca accgctcaat
    37081 cttttgcaga tgcgaatttg tttgatctgt aagaggagga actacgattt atactattgc
    37141 actattactt catttacttc aacgggcagc ctatttctat agcattatct tgatggtata
    37201 tgcattgctc tcttggtttc caggcgggta tcaatcaggg ctaggacgat tattagctaa
    37261 gatctgcgaa ccgtatatca gtttgttcga tcgtctgcct ttgaggattg gacccttgga
    37321 tttcacaatt ttaggggcaa tcctgatctt gaacttagcc gtacaaggtt tagcacagat
    37381 cgttatatgg ataactgtcc atttagttta ttgattgaag caacaaaatc tttattctca
    37441 gaatagatag gaggggaaaa ttttggatgc aaatgtatac cagcactttc gggcagatga
    37501 acgtacattt atcgattcgg taggcgattg gattgaacag gttcaaggac aatatgcacc
    37561 ctatctgacc gaatttcttg acccaagaca atcctatatt ttagaaacac tgattcgaca
    37621 aagcagtgat ttgcgtttca tgttttatgg cggatatgaa caggcagaaa gaaaaagatg
    37681 tttgattttc cccgattatt acgaacctgt agaggaagat tttgaaacag cattgtatga
    37741 aatccattat cctagcaaat ttgccagcct aagtcatggg aaaatccttg gaactttagt
    37801 gggaacgggg atcaaacgct cttactttgg cgatatcatc tcggacggtg atcgctggca
    37861 agtatttatt gcaaatgagg tggatcattt tgttgctgca caagtaacaa agattggaaa
    37921 ggttgctgta cgcttggaac caatcaaata cacagaaatg attatgccga aagatagctg
    37981 gacacaagaa agaggaacag ttagttccat gcgactagac agtgtgatct ctgagattta
    38041 taatatttcc agacagcggt ccaagcagct gatcgaagct ggtaaagtaa aagtgaactg
    38101 gacagaaaat acaagacctg attttgtact tgaactatta gatattattt cagtcagagg
    38161 ttatggcaga gtccagatcc aagaacttga ggggaagacg aaaaaagaaa agtacagggt
    38221 actgttcggt gtattacgta aataaaataa aaaggtggtt tactcatggc tttaactcca
    38281 ttagatatcc aaaataagac attcccgaca aaaatgcggg gatataatca agacgaagta
    38341 gatgatttct tagatttagt tgttcgtgac tatgaggaat tgactcaaag aaatcgagaa
    38401 ttagaaaaag cagtcaaaca ttctgaagaa aaacttgagt acttcaatga attaaaagat
    38461 gctttgaacc aatcaatcat cgtagctcaa gatacggctg ataaagtaaa aacaagtgca
    38521 agcaaggaat ccgaagtgat cgttacttct gcacaaaaca aagcagatga gttagttgcg
    38581 aacgctgaaa aacgtgcaca tcaattaaca actgatgcag aagaaaaagc aagaaaaatc
    38641 ttgacagatg caacagaaaa agcaagacag cttgcgacag aaactgaaga tcttaagaaa
    38701 aaaacacgag tattccatca acgtatcagc ttgatgcttg agtctcaatt agaacaagtg
    38761 aaaagtccgg aatgggatga aattttacaa ccattctcca gctacgtgac tgacagccat
    38821 gaagtgatca aagaagtttt agcaaaacag cttgacaatg aaaatgatac tgatgtaaac
    38881 tcagacacag gagtcataga agcacctatg acggcatttg atacacaggc tattgatatc
    38941 tcgatcgtgc ctggtgaaaa tgaaaacgag tagaacagaa aagcactttg ttattcttaa
    39001 agcgagccga tgagagtgga agttcggtaa gacactgcat ggtgaaagat cctctacttg
    39061 agacctgctt ttccgaaatt agagtaagaa gcagcggctg acctcgttat tggtcacaga
    39121 gagtttgcac tagatagatg caactaaatt tgggtggtac cacggcatgt tcgtcccttg
    39181 cggctgaaca tgcttttttg tgtccggaaa acaaataaag gagtgtatgg ttgaatgaaa
    39241 atgaaagaaa ccttgcaatt aggaaaaaca aaattcccta tgcgtggtaa tttgccaaac
    39301 cgagaaggcg agtggcaaaa agaatgggaa gaaaatcgaa tctaccaaaa aagacaagag
    39361 ttgaacgaag gaaaacctag ctttgttctt catgatggac ctccatatgc caatggtaat
    39421 atccatttag gacattcatt gaataaaatc agtaaagaca ttatcattcg ttcaaaatca
    39481 atgtctggct atcgtgcacc atatgttcca ggatgggata cacatggatt gccgattgaa
    39541 caagtattgg ctaataaagg cgtgaaacgt aaagaaatgt ccatggcaga atacttggaa
    39601 aaatgtcgtg aatatgcact ttcccaagta gataagcaac gagcagattt caaacgccta
    39661 ggagttgcag gagattggga acatccttat gttacattag atccttctta tgaagctgca
    39721 caagtacgcg tatttggtaa aatggctgaa aaaggctata tttacaaagg attgaaacca
    39781 atttactggt ctccgtcaag tgagtcttct ttagcggaag ctgaaattga atataaagat
    39841 gtaaaatctc catctatttt tgtagctttc aatgtcaaag acggcaaaga tattcttgat
    39901 gaagatacag cttttgtcat ttggacgaca acaccatgga cattgccagc aaaccaaggt
    39961 attgctgtaa atccaaaatt tacgtatgta ttggtggaag ccgatggccg taagtttgtc
    40021 gtagcgaaag atttgctaga aacagtccaa tcagaaatcg gttgggaaaa tgtaacagtt
    40081 ctaaaagaat ttgctggaca agaaatggaa tatatgactg caagtcatcc attctatgaa
    40141 cgtgaatcac ttgtgatttt aggcgatcat gttactttag acgctggtac tggattagtc
    40201 catactgctc caggacatgg ggaagatgac tatatcgctg gtagcaaata taaactatct
    40261 gtagtgtcac ctgtagactc aaaaggattg tttacagaag aagcacctgg atttgaaggt
    40321 atcttttatg acaaagcaaa tcctatgatc actgatctat taaaagaaaa aggagctttg
    40381 ctgaagctag atttctttac tcatagttat cctcacgatt ggcggacgaa aaagcctgtg
    40441 atctatcggg caactccaca atggtttgca tctatcgata aattccgtca gaatattttg
    40501 gatgaagtag aaaaagtaga gtgggttatc ccatggggta aaacacgttt gtataatatg
    40561 atccgtgacc gcggcgattg ggtaatttcc cgtcagcgtg catggggagt accacttccg
    40621 attttctatg ctgaaaatgg agaagcaatc atcacaccag aaacaatcga acatgtggca
    40681 aaattatttg ctgaacatgg atcaattatc tggtttgaaa aagaagcgaa agaacttctt
    40741 cctgaaggat ttacccaccc aggttctcct aatggcgaat ttacaaaaga aaaagatatc
    40801 atggatgtct ggtttgattc tggttcttct catgaagctg ttttacgtca gcgaccagaa
    40861 ttatcattcc cagcagatat gtatttagaa ggatcagacc aatatcgtgg ctggttcaac
    40921 tcaagtatca cgactagtgt ggctatcaat ggtgtagcac catacaaatc agttatttct
    40981 caaggatttg ctttagatgg tgaaggccgt aagatgagta aatctttagg aaacatcatt
    41041 gcaccagaaa aagtgatcaa acaatttggt gcagatatcc ttcgcttatg ggtatctagt
    41101 gtagattatg aagcagatgt tcgtgtttct atggatatct taagtcaagt ggcagaagta
    41161 tatcgtaaaa tcagaaatac gatgcgtttc ttattagcga atacagaaga tttcgatcct
    41221 aaaaaagata ctgtttcgta caatgattta cgttctgtag acaaatatat gaccgttcga
    41281 ttgaaccaag taatcaaaga aatccgagaa gaagggtacg acaaatataa cttcatgcat
    41341 atttaccgta cagttatgaa cttcttgacg gttgatctat cgtcattcta cctggatttt
    41401 gctaaagatg tagtttatat tgaagcagaa gatgattatc aacgtcgttg catgcaaact
    41461 gttttctatc aaacagctgt agctttgaca aaattattga ctcctatcat tccgcataca
    41521 gcagaagaaa tctggtcatt cctgaaagaa gaagaggagt acgttcagtt aagcgagttt
    41581 cctggttatg aagagtttgc aaaccaagaa gaattgatgg atacctggac tgctttcatg
    41641 gacttccgtg ataatgtctt aaaagcattg gaagaagcaa gaaacagcaa attgattggt
    41701 aaatctttgg aagcaaaact aactgtttat ccaaaacaac aagttcgtga aatgttaaaa
    41761 gctttggatg cagatattgc acaattattg atcgtttcac cagactactt tgaagttatg
    41821 gcagcagatg aacaagtgcc agataacgct atggtatttg atgatgttgc tattacagtg
    41881 gaaaaagcag acggggaaac ttgcgatcgc tgtcgccaag ttcgtaaaga tgtaggagta
    41941 gatgaaaaac ttcctcatct atgcggtcgt tgtgcaaaaa tcgttgaaga cttctatcct
    42001 gaagctgtag ctgaaggatt cgaagaaaag taaaagggaa aagggggtgt gacatgttct
    42061 ttgtcacacc cccttttgtt atcaatcgtt taattttcca cgttcacgat accagttatc
    42121 tggttgccag atccattcga atccgtcttt ttcaagtagt tcgaaagctg ctttaggtcc
    42181 cattgatcca gctttgtagt tgggaaaatc cggttgtgtt tggtcccaag cttttcgaat
    42241 gacatccacg atatgccaag attgagcgac ttcttcccaa tgagagaagt tcgttccatc
    42301 accattcaac gcatctaata gtaatttttc gtaagcttct gggctatttt caaccatttc
    42361 tgcactattt ctaaattcca atttgattgg ttccgtttca aatccttgcc ctacttcttt
    42421 cccattcaag gataaagaaa atccttcagt tggctgaata tagatcgtta gaacattagg
    42481 tggaagtgtc gtatcgtcac atggttcatc gacagatgtt ttgaatacat taacaggaac
    42541 ttgtttgaat acgatgttga tccgagtccc tttttcagtc aaacgtttgc ctgtacgtac
    42601 atagaaagga acacctgacc aacggaagtt atcgatagtg aatttgcctg cgacgaatgt
    42661 ttcagtctct gattgagcat ccactttgtc ttcttcgcga tagcccttga attgtacacc
    42721 atccaattca ccttgagcat attgcccgcg aacgaagttt tctaacactt cttcttcgtt
    42781 ataaatgcgg atagctttca atgctttgat cttttctgta cggatttctt tttcggaaaa
    42841 tgctactggc ggttccattg caagtaatgc tacaacctgt aaaatatgat tttgcaccat
    42901 gtctttaagt gcgccactat gatcgtagta gcccccgcga tcttctacac cgaggttttc
    42961 gccaaaagta atttggatat tgtcgatata gcgattgttc cattgagcct caaaaatatt
    43021 attggcaaaa cggatagctg agatgttttg gatcatttct tttcctaaat aatgatcaat
    43081 cctgaaaata tcttgttctg ggaatacttc tctgatttgc tggttcaatt caaaagcaga
    43141 ctggtaatca gaaccgaacg gtttttctat gatcaaacga ttgaagccat tttttgtcat
    43201 aatattttgt gatttcaaat gagaaacgat cgttccaaaa aattgaggtg ccatagccaa
    43261 ataatagaca cggttaccgt ttaattgata gtgtccatct aatcggtcag acaattcttt
    43321 taatgtctga taatgcgttg aatcatttac atcatgggat tgatagtaaa aatggcttgc
    43381 aaaggtagtt gcttcttcat ctgaaggatt caatgcacgg attgtttctt tgacaacttc
    43441 acggtagtgc tcatcgctcc agggacggcg agcggttccg attacagcaa aatgctcgcc
    43501 taaatttcct tttctgtaaa ggcggaacaa agacgggtac aatttacgct gggctaggtc
    43561 acctgtaccg ccgaatatcg taaacaatac atttttttca ttagacatgt ggatacactc
    43621 ctttatattt tatcgacaaa aatcgtgctg gccgccttaa agctgacggg gattttcttt
    43681 ctatcatttt ggatagtgat cggtccttca taagctgcga tgtcaacgat ctcatattct
    43741 tcgttgatat tcaggtcaat agtgactaag taatccaaca attctttttc atcaagcact
    43801 cgtgcgatac gcacttttgt accgacagga taggactcca atgtttgtcg gcgttcttca
    43861 tggacaactt cctctttttt aggaatcgat cctccatgag gacaatgttc aggatgattc
    43921 aaatagtttt ctaaatgatc tgcaagatgt tccgaagtca catgttccaa tacttcagca
    43981 tcatcatgga cttcattcca gctatagtct aaatgttcaa ctaaaaaaac ttcccataag
    44041 cgatgtttgc gaatcagact gctagctttt tgcagtccgc ttgcagtcaa ttgtacacct
    44101 tgataagggg aatgttctac aagctcttct ttcacaagtt tagaaatcat ttcactgaca
    44161 gatgcagctg agacatctag actagatacg atttgtttat tgttgacttt cgttgtatct
    44221 ccacctagtt ctaaaatgat tttcaaataa tcttctcgat ttggtgtcat attcgatcat
    44281 cctttcatgg taaaaaacca tcattagtaa gtgtaacaaa aaaaacgtta attgactatt
    44341 tttctaaata aaaaacaaag gatttttaga cgtttttaca acaaaaaacg aaagatgata
    44401 gagaagactc attctttcgt ttataaagga tatatatata cattgggagg gatctatttt
    44461 tcagataaca acttatatga agtgtctgca gattcgtcat aaagagtttg ttcgggataa
    44521 gaaaagataa gataaaaacc atactgatca cgtacgacta aacgatattc atctatttct
    44581 accacagatg tgccaagaga ctgaccgttg atcaaaaacg tgtaatcaga tgtaatctgt
    44641 aattgttgtt tttgctggct atcactaaag aaccatgtac cttgatactt tgagagtcct
    44701 tctgactttt ccgcttgttt tttctttttc aagtaaataa aacttgagag aacggtaatg
    44761 agtgaaccaa gaaaatagat catttttttt atcaccaaat cactccttta tgagaaaata
    44821 atcgcataga catattcttt cttctttatt tcattgtacc gaataaaagc taaaatttct
    44881 ctaagacttt cgactggttt ttttactgtt tttctacaaa ttatgatagg atacatagta
    44941 ggaagaaagg tgacataatt tgaagtatca gcaagtggaa atagcttttt ttattgaccg
    45001 cccgaatcgg tttatagcac attgtatgaa aaaagacgga gaaataatta ttgcgcatgt
    45061 caaaaataca ggtagaggaa aagaggtcct gataccaggc gctgaagtgg ctattgtatt
    45121 tgctcctgga cctaaacgga aaaccgccta tgatctgatt gctgtaaaaa agaagggtga
    45181 ctggtttaat atcgatagtc aattgcctaa tcggctggca attgatggta ttttagacgg
    45241 cacgatcctt ttaccaggat taactggtcc atttacggta tacaagcgtg aagtaactta
    45301 tcttcactcc aaatttgata tttatttaga gacggtggtc ggacaaaaag catttgttga
    45361 agtcaaaggt atgacacttg aaaataaagc gattggtgct tttcctgatg cgcccacact
    45421 cagaggattg aaacatatag gagaattaac gtatgccgca caagatggtt atgccgctta
    45481 tgtcttgttt attgctcagt tcgaacatct tcatctggca acgatccatg aagaaatgca
    45541 accagcacta gctgatatgg ttcgacatgc gcagcaaagc ggagttcaaa tcctcgccta
    45601 taattgtcaa gtatcggcag atgaggtaac tgtcaagcag gccattccat ttgatgtaga
    45661 tatccctttt gaagatccta tacaatagaa agaaggtaaa ataatgatca acttaggtat
    45721 tatcggaaca aattggatta ctcatcaatt tgtccaagca gctttaagca caaaaaaata
    45781 tgaattgaca gcggtatatt ctagacattt ggaaaaagca caggaatttg gttctcatta
    45841 tgaaggggat atcgaattcg caacagattt gaagactttt ttcaatatta ctcatatgga
    45901 caccatttat attgcttctc cgaatagtct tcactttagt caagctaagc aagcaatttt
    45961 ggcaggaaaa aatgtgatag ttgaaaagcc agctttttcg acgccaaaag aaatggatga
    46021 aatcatccat ttggcaaatg aacacaatgt gtattttttt gaagcagcaa gaaatatcca
    46081 tgaatcaggt tttaaaaaga ttgccgatta cttaccatta aaagacgaga taatcggtgc
    46141 aaatttcagc tatatgaaat attcttcgcg ctatgaccaa gtattagatg gagaagaacc
    46201 gaatatcttc tcgactcatt tctcaggtgg tgcattgatg gatttaggtg tttaccttgt
    46261 atatgcagct gttgcttggt ttggaatgcc aaaagaagtc cattatttcc caagaaagat
    46321 ttctactggt gtagatggtc ttggatgggg gatcttacgt tatgagaatt ttgatgtatc
    46381 gatccagcca ggtaaaatcg gtgattctta tttaccgtca gagatttatt ttgactcagg
    46441 aacgctagtg atgaatggag tcaatgcaat tgaacaagca caatttcatg atcgcgcgca
    46501 taaagaaatc attgatttgg cggtaacagc tgcagaaaat ccaatggcag atgaagcaga
    46561 ggattttgcc aatgtcatgg ctcatccgaa agatccagct tggggattgt tgtatgaaga
    46621 gtggatcgag ctagctagaa atgtgaacca agtgatttat gatttaagaa aaaatggcgg
    46681 catcaaattc gatgcagata atgaggaaga tttttaatga acgaatttgt acaagtattt
    46741 cccgaaaatt ggcagaaaaa atatgaggat aaagggttta tctcaccttc tcttattcaa
    46801 cgagcagttt ttcagccact aagtaataaa caaagtatag tagcggtttc tcctacaggt
    46861 tcaggtaaaa cactggctta tctttggcct ctactactaa acgtggaacc aggtgaagca
    46921 agtgcgttgg tcatttttgc ttcttctcaa gaactagcta ttcaagtagc agatgttgca
    46981 cgtgaatggg gaaaagacaa agagttgaaa gtccaatctt tggtgggcgg agccaacgtc
    47041 aaacgtcaga ttgagggttt gaaggaaaaa ccagaaatct tgattggtac accaggaaga
    47101 atattggaat tgatgaaagc aaaaaaaata aaagcacatc aagtgaaaac aatggtattt
    47161 gatgaagcag accagctatt tgacgctggg aacagccaaa tcattgatca aattcttcat
    47221 caagctccaa cagagtatca gctagctttt ttttcagcga cagcagatcg ttcccttgaa
    47281 agcattgaaa aaatcactgg gaaaacgttt gagacaattg acgtgacagc agaggacgat
    47341 tctcgaaaag gactgagaca ttacttttta cgtgtaccga tacgaaagaa agatgactac
    47401 ttgagacgtc tcacgcatat agaagatttt catggtctga ttttctttaa tcaactgact
    47461 gaattaggcg taatggaaga aaaattgctg tatagaggtg taccggtagg aagtctggcc
    47521 tctgatcaga acaagctact ccgaaaagca gcgctagaac aattcaaaaa gaaaatggtc
    47581 agagcacttt tgaccacaga tgtggcggct agaggtttag atattacagg tcttccttat
    47641 gtagtgaatg cagaagttcc gttaagtgaa gaagcttatt tgcatcgttc gggaagaact
    47701 ggtcgaatgg gtaatgaagg aatagtaatt acactcgtac aagataataa tctaagagat
    47761 ttaaaacggc ttttacgtcc atcaaatata acacttgaag agattttttt atacggaggt
    47821 aagctgcaaa ctgagcagcc aaccaaagaa gatgcagctc ctgcagtaaa taaaaagtat
    47881 gcgaaaactt tttctggaaa ggagcagaac ccagaatata acaaagaaaa aataagaaaa
    47941 aaagttaaaa ataaatcaaa aaaagagaga aataaaggag caaggcgcaa ataagcgcct
    48001 ttttatgcta tgattatgaa aacgggaaca aaattggttg ccagaggagg ggttatgtga
    48061 aagaacgtca agaagagatc ttgcagctat tgacagaaaa ccaacaagga ttgacagcaa
    48121 gtgatgtagc tgagcgctta actatcgatc gaagcaatgc aagccgatat ttaagtgaac
    48181 tatacaaggc ccatcatatt gtaaaaaccg ctggccgacc agtcgtttac tctttgccaa
    48241 cggaaaagtc aaaatctgat gaagtgcatg tcgactcttc tacgcaagtg acttttgaaa
    48301 cactcgttgg agaaaatgat tctttaaaag tcagcataca gcaggcaaaa gctgcgattc
    48361 tttatccacc gcgggggttg catacgatta tttttggaga aactggtaca gggaagtcga
    48421 tgtttgctga atgtatgtat cattttgcaa tcgattcaga gatgctttct gcagatgcgc
    48481 catttgtttc tttcaattgt gcggattatg ctcaaaatcc gcaactgctc tttggacaca
    48541 tctttgggat caaaaaaggg gcttacacag gagcagctca agatagtccc ggtctaatag
    48601 ccaaagcaga cggcggtata ttgtttttag atgagatcca ccgtttaccg ccggaagggc
    48661 aggaaatgct gtttactttc attgataaag gtatttaccg tccgcttgga gaaagtgcac
    48721 aagtacatga agcatctgtt cagatcattg gggcgacgac tgaatcttca gaaagtttct
    48781 tatctacgtt caatcgacgg attcctatgg caatcacctt gccgaatctt gcttcacgtt
    48841 cactggatga gcgttatgaa atcatctctc tttttatcaa acaagaagcg aatcgtttga
    48901 atcaacgtat cgatatcgaa aaagaagcga ttcttgcctt catgctttat gatgcggaag
    48961 gaaatatcgg tcaagtgaaa cgagacttga aactagtctg tgcaaaatct tttttacatt
    49021 accgtactca tcatgagaaa aagctaatca ttcgaaaaga agaactttcc cttcaagtac
    49081 aaaaaggatt actgaaaatc aaggaaatac cggaacgtct cgaccgattc atggacagca
    49141 aaagtcagta tttgacattt gaaccaggat ttgctgatgt tgtctggtca caagatccag
    49201 aacgaaacat gcaggtctat aacgatattg aggaaaaagt cacttctctt tccgaaaccg
    49261 gtgtggagaa cattgatcta gagaccctca tttcaaaaga tgtggatgct tatttccaga
    49321 catatgtcaa agaattgact aaaagttcga ttcccaaaga tcttttgcca gatgaaatct
    49381 ggcggttaac caatcaattg tatgatgtgg ctgaaaaacg gttagaccgt atttataatg
    49441 aaaaagctcg ttttgctttt gctttgcatc tgcaaagtac attggatcgt gtgagagaag
    49501 gtcatatgat cgtccaccca gatttgaata acgtacggaa aaattttaag agggaattcc
    49561 aggtagcaat cgatctttca acgatcattg aagaagaaga acaagttgag attccttttg
    49621 atgaaatcgg ctttattagt atgtttcttt ctatcaatct aggagaaagt gagcctgtta
    49681 aagaaaacaa agtagatgtt ctcatattga tgcacggcag acagactgct tcaagcatgt
    49741 tggagatggc acaagaacta ttaggaacaa aagtagggaa agcttttaat atgccactgg
    49801 ttatggaagt tcaaacaatg tatgaagaag tgttacaata tgtcaaaaac tatcaagagc
    49861 atttgacgaa tggcctactc ttgttaacag atatgggatc attaaacacc ttcagtgatt
    49921 tgatttatga agagactggc attcggacga aagctatcac gatgacaagt accatgattg
    49981 tgatagaagc gatacggatg gcaagtgttg gaagaagctt agaagatatt tatcaaaata
    50041 tccagctttc ctttgaatcg atcgtacgtg atcagttcaa agcggaaaag tctgaaactt
    50101 tacagcgtaa aaaagccgta atcgtgacat gctttactgg tgaaggagta gctgccaaat
    50161 tatatcagcg tattatgcca gtgattaatc aaaataaggt agaactgatc cagatgcagt
    50221 ttttagaacg tgaatcattc aaaaaacaca tcgatgcctt attggaagaa tatgagatca
    50281 aagcaattgc gggaacagtt gatgttgatt atcaaaatat cccatttttt tcagcctatg
    50341 acgtttttga tgatgaaaaa ctaaatattt taaagcgtat agctgatgat gagatcccga
    50401 cagctaaaat tgtcgattca cttgctggat cattaagcga tgtcttttct attgatgaac
    50461 tgatccgttc attgcaaaag acagttcagc agatccagac cgatttgtcg attatcgtgg
    50521 aacctggagt agatactgga atcgttatcc atttagcctt catgttagac ggattgatca
    50581 aacaagaaag ccatcggcaa tttgagaaac tgtctatttt ctcaaaaatt tatcgtttgg
    50641 aaatggatat cgttcgggca aacttgatgg cactagaacg aaaatatcag gtaaaaattc
    50701 cagaagatga tatcgcattt cttacacaaa tgtttcttga aaataaaata aaaaaatgaa
    50761 cacactaatc atactgttta cacactaaac atctgtgtgc gcactataaa aaagagctaa
    50821 aaagcatgaa aacgctattt cagctctttt ttttattggc atgcttcttg cgttatataa
    50881 aagtgtaaaa aaataaaagg agtgttaaaa atggcaaaaa aaacaatcat gttagtttgt
    50941 tcagcaggga tgagtacgag tttattggtc acaaaaatgc aaaaagcagc agaagaaaaa
    51001 gggatggaag ccgatatttt tgcggtctct gcctcagatg cagataataa tttagaatct
    51061 aagaatgtcg atgtattatt attaggtcct caagtacgtt tcatgaaagc tcaatttgaa
    51121 caaaaacttg cgcctaaagg tattccatta gatgtcatca atatgcaaga ctatggcatg
    51181 atgaacggag aaaaagttct tgcacaagca gaaaatctaa tgaaataaat caagtatgca
    51241 gttgggggta taacaacgtg gaagatcaac aaaatctaga agccatcatg gggttaatca
    51301 tgtttggcgg taatgcaaag agcgatgcaa tggaagcgat tgcggctgct aaaatcggtg
    51361 attttgagtt agcggatagg aaaatcgctg atgcagaaga atcacttata caagcgcatc
    51421 atgcacaaac agacatgttg acacaagaag cacaaggaaa tcatatgcaa gtgacattat
    51481 tgactgttca cagtcaagat cacttaatga catctattgc gtttactgat ttagcaaaag
    51541 aaatcatcga actttatcgt cgcgtataca gcgaataaat acaacttctt ttttgaacgg
    51601 aagaagaaaa atttttgaac ggatttttta ttttgttata aggagaactc tctttatata
    51661 aaaaacttat aggaggaagt aaaaaatgaa cggactatca agttggatgg agaaatacat
    51721 cctgccggtt gccgcaaaaa tcggagcgca aaaacattta gttgctttgc gtgatgcttt
    51781 tatcggcata ctgcccgcaa caatggcggg atcagtcgct gtaatgatca atgcaattat
    51841 tcgtgattta ccgcaacagt ttaacagtac ctatgctgac agtttagcag cagacaaagg
    51901 aatctttgcc gtattgaatg tcatcatcgg aatcaatggt tttgtctgga acggtacact
    51961 agcaatcgcc ggattgatct ttgccttttc ttgggggtat aatcttgccc gagcttatgg
    52021 agtaaatgat ctagctgggg ggatcgttgg tttagctacc ttgattcaag gtatttcctt
    52081 tggtccagca ttatcagcag cattagatgt gaatgttcct tcaaatgtcg cagatgcaat
    52141 caatagttct gagattggtg caacgattgc agatggcaca ctgtcagttg gattatgggg
    52201 ttggctaaaa ctagatcatt tgaatggaaa cgcttatttt acagttatga tcatgggagc
    52261 tatttcagtc attatttttt gtaaattgat gcttgccaac attacgatca aaatgcctga
    52321 ttcagtacca ccagcagtat ctaaagcatt tgcagccatt ttaccagcga cgatcgcttt
    52381 atacgtcatt gctattatca attatatcgt aggtcgtgta gctgatgggc aactgatcat
    52441 tgatttggtg caaaaatata ttgcagaacc attcctagga ttatctcaag ggttgggagc
    52501 agtattgatc gtcacagtat ttgttcaagt attctggttc tttggtattc atggatcaaa
    52561 tgtattggca ccagtgctag agggaatctg gggacaagca caactaatca atattgatat
    52621 tttccaaaaa ggttataacg gaaaaactgg tacaccagcc gtgttagatg caatcgaaga
    52681 tggaaaagct tatatgtggg tccgcggatc gttcgatgct tttgcatggt ttggcggatc
    52741 aggcggaacg atcgtcttac tgatagctat cttgattttc tctaaacgtg cagattatct
    52801 aacagtagct aaattatcca ttgggcctgg tatcttcaat atcaacgaac cagtgatgtt
    52861 tggtctgcca atcgtattga atgcaatcat gtttatccca ttcttgattg ctccagtagt
    52921 agcaacagca attggatgga cagctactta tcttggccta gtcgctccgg tatcgcagca
    52981 agtcacatgg gtagtaccgc cgttcttatt gtcattctta gcaacaggag cggattggcg
    53041 ggcaccgatc gtaacattag tatgtatggt cgtgactttc ttgatttggg caccatttgt
    53101 catctctgca aacaaaatgg accctgccgc aggcgaacaa caataagatg aacgtgagga
    53161 gcgggacgct ttaagtttcg ttcctcataa tgaattttcg aggaggaact gaaatgatta
    53221 caattgccag tgcaatgcaa caagatgaaa tcaaagaatt gttagaagga tacaatgaag
    53281 aaggaatgac ttttacattt aaagaaaaac aaggaatcaa gctgttcttt gaaacaagtg
    53341 cagaagatcc ggaagttgcg gctaaaaaag caaaggaact aatcaaagca cagccttggg
    53401 gaacagtcct ttattttcaa tcaacagctg tttagaaaat ggtttaaaaa gataggatgg
    53461 ttgagatgat aaaaaacggt ttatttttat gtagtattgg ttctttgatc gtgttgtata
    53521 gtttgaatcc acattcgcaa aggtatgatt tgtatagtat ggtcacaggt ctttttctaa
    53581 caggattagg aatctatttc ttcatgaagg ggaaaaaaag agaagaagca aaggagaaaa
    53641 ataactaatg gaaatcacga aaaaattaaa tattccagca tcgttttttt acgataaagt
    53701 tatggactct gtccttttcg atgtacgtaa agcgaccggc aaatcagtaa ctagaaaaca
    53761 gctgaaaaat ttggagtacg tcaaacaatt ctcgcaaaat aaccgggctc gcataaaaat
    53821 cgaagaagtc attgaaaacc agtcttataa gtttcgtaca tcgacaacga agaatgaatt
    53881 cgtcgttcat tatcaaatca aaccattgga cgattcgacc tgtgaggttc attacacaga
    53941 aaaaatggag tcttatggca tgcttcaaaa gttgaatgat atgcttttag gaacaatctt
    54001 gatgtatttt aaacggagac gtttcaaaaa aatgctagat atgatcgaag caacgtatta
    54061 aatcaatgaa acatggtact atttagttat tgaaaaatga agtaagctag aaggaatttt
    54121 tcataggaag atagatcttt cctgcgaatc ctcactagct tttttgtagg aaggggcagc
    54181 aaaatgacaa acaaagtaag agagctaggt gtatcttcga ttgaggaaat gtttgattta
    54241 gccacttatg catttaatgg ggcagataca cctgaaaggc gagaacgttt tcgtacactt
    54301 gcggagaatt cttggaatta cggatttttt gatgaggagg atcggctaac aagtcaagta
    54361 atggcgaccc cttttccagt gaatttttac ggacaagagt acctaatggc cggcattggc
    54421 tatgttgctt cttatccaga agcaagggga caaggcggga tcaatcagat catggaaaag
    54481 atccttgaag attgccgtga tcgtaaagta agcttatctt atctggcgcc attctcctat
    54541 cccttctatc ggcgctatgg ctatgaacaa tcatttgata aaatcagtta tcaactaaac
    54601 agtcgtgatg tgccgtttat caaaaaaaaa tctggaaaaa taaagcgtat ggattttgaa
    54661 gatgcaaaag ctgcaatcag aagaatttat gaacagatgc cggaaaacca acgagctggt
    54721 ctgaagcgcg aagactggtg gtatacgtat aaattcaagc aaaaaggcaa ttaccagttt
    54781 gctttgcatt ttgatgataa tgaggaagca acgggatata tcgtttatca gcttgcaacg
    54841 tcttccttta ttattgcgga gtggggattt ttggatcatg atgctttttg cagccttgtt
    54901 cgcttcgtaa gttctcacaa tggtgctttt gaaacatttg aatattcatg cggctacggc
    54961 ggtaatgatc aaaattatct attagaaaat ccatttgctt ctgtaatgat cacaccttat
    55021 atgatggcga ggatcgtaga tatttctttg tttttggaaa attatccatt taaaaagaga
    55081 caagctgcat ttgccctaca aatagaagaa gatcattatg cgaaatggaa tgaaggaatc
    55141 gtggaagtaa caatcgaaaa tggaaaaaat catctctcaa aagtagaaca aacaaaactc
    55201 ccaatcgttc gaggaagtat ccaacatatc acgcagctat tattagggta tcgtaaagtg
    55261 gaagagttgg tattccaaga aagaatacag gtgacaaaag aatatgaaga aacgttaagc
    55321 tcaatcttgc cacagcaaca gccaattctt aatgactatt tttgataaaa aacgggtgat
    55381 gacaatattt ttgtcaccac ccttttgttt ttcatttggc atttgaagga aaatgttaaa
    55441 gtaaatcctc ttttttcgta aatttgaatt ttttgttttc ttttgtttta gggttttctt
    55501 ttttgtggtc ttggattgct tctttcgtaa tcttttcccg atttttttta gatgaatcta
    55561 agcgttctgc gtatactttt tcttttggct tatcattcat tggaaaggac ctccctacat
    55621 tatttcattc tacctctagt ttatcatctg ttaaggacta gtggaaacgt tttgcctaac
    55681 ttataagctg atttttttag cagataagct tgcaagtaaa aaacaaacaa gctacaattg
    55741 atttattgaa attgttcctg tagctcagta ggatagagca atcgcctcct aagcgatagg
    55801 tcgctggttc aattccagtc aggaacgtat aaataacccc tgtatccttt gtggtacagg
    55861 ggtttgtttt gtatttgtgc caaaaatgtg ccaaactagt tatcattttt atataaacta
    55921 tcgaatacag cattgatttt ttctttatcc tgatcttcaa gttctcgaac gatatgaaga
    55981 taagtagaca ttgtagtttc taaactgcta tgtcctaacc gttttgatac gctaagtata
    56041 tttactcctt gataaagtaa aatagatgca tgtgtatgcc ttagtccatg caaagtaaat
    56101 tgcttttcaa tccctaattc ttttaatttt ttgcgcaaat atttgctgac ggcatttgat
    56161 gaaactaatc cattttttaa gttgaaaaaa acaaaattat gagggttttt aacttcaaaa
    56221 ttctcgaata attctttttg attgatttta aactttttta agagatcaat cgtatgttta
    56281 tcaattgaaa ttttccgatt tgaagtctcg ttttttgttt ttccccattc atttaattta
    56341 taattccatg ttttattaat agtgatgatt tgatcttcga aatcgatatc ttcccatgtt
    56401 aatcctagaa gttcagcaaa tcgcattcca gtagcaccag caactaacac gagcatagga
    56461 gaagagtact gtgcagaaag gttttcttct acgagtttca ttaaagattt aaattgatca
    56521 taatctaaat atttatcttc ttttggcttc aatgaatctt ttcctttgat tactgctttt
    56581 ctagttggat caaacggaat taatccttct tctacggcat ctttcaacga tgctctaata
    56641 tggttattaa acttaataac ggtggatttt acatggtctt tcgcatactt atttaaaaag
    56701 cgttgatatc caactctatc taaatcagaa atcaatactg ctggcatata tttctttata
    56761 ttcattaacg tatcttcgta ttttctataa gtgataggag atactgttcc ttctttgtag
    56821 agttgcatcc aatcttcaaa gtaatctgat aataatagat ttttgcgatc ccctttaaga
    56881 cctttattca ggttatattc taattcgttg gcggcatctt ttgcttcgcc ttttgtcttg
    56941 aatcctgatt ttcttatctt cgtgtatttt ccgtcatctt ttttgtatga aatttcgtat
    57001 tgccaactat ttccacgttt gactaatctt gccataattg aatctactct ctttctctga
    57061 tacaataggc actgtaaaga agcctattgt gtaggtttgt ttttaacgcg tccacaaact
    57121 ttggcgaggg agggggcgtg ttttttattt atactctgtt gttcctgctt cgccaatcgg
    57181 ctcagctgta aaatcatcag taaattgttt agacgcatta agtttaaatg tacttaaatt
    57241 tggtttattt ttagaaagta aatagaaaac cccagatgtt gtcgtttcag gttgaactaa
    57301 agaattagaa ttttcgtcat ataagaaata ttctccagct gttctactat attccatacc
    57361 gtctccatct attaaagatg cctgatacga agacaaagag aaaggtgatg ttgctttatt
    57421 ttttaacttg taagaaatag tagtacgata gtatttttct ggaaaatttt ctattccact
    57481 aaagttatat tcggcatttg taaaattatc ttcgtcattt gttacctgtt cagtttttat
    57541 agaagaaatt gtatattcta ggataccaac aactggcaag gttttttcct tagaagcatt
    57601 gtcgatagat tcgctatttt cttcagtgtc atttgactgc gatgctattt gttttttaag
    57661 ctcttcattt tcttttttta aactattgat tgttttttga gtttcactat tagttgcatt
    57721 atttgaaggc gaactacatg cacccaaagt taaaatacta gtacaaataa atcctaatat
    57781 taagtttttt ttcattttta attcctcact tctatgatat tatttttatg tagaatctta
    57841 gaaatgagat tttagtccgt gttgcagcac gggctttttt ctttataact ttttagaggt
    57901 tataggcaag atagtgggac acaaaaatat attattgtat tccgtattta gaaaatccta
    57961 attgaacttc accggaagtt ttttgctgtg ttgtacgcaa tgcttcttct tcagacattc
    58021 cattctgtac tttccatgca acaggcgaca tcccgtattt gttaacaaaa tcagtaagtg
    58081 ataaagtgtc agcgtcttgt tgagcgcttg tttgttgggc ttctgtattt tgttgagatg
    58141 cagcttgttg ttctttctga tcttgactga taatattgcc agcatcatct gtagtcaatc
    58201 cattttcata aagggccacg ccgaaagctt cccactcttt gttggaccaa tttgcacgat
    58261 cagctggagt tgactgtaaa gtgcgttgtt tcatctgttc atatgtttct tcttgaggtg
    58321 cggtttggat tgtatcctga ctggagctta taactgttgg gctaggtttc gccgtagctt
    58381 ggttggagct tgtaactgtt gaactagaat ctgttttaga tgtagatttg ctagtagatg
    58441 aactgatttc agttgtttct tttgttttac ttatatttgt ttcttggtta gaagtggcat
    58501 ctgttgattc agctttttta ttatttgaac aagctgaaag tagcagagca gtacttaaca
    58561 acaacataac gctaactttt ttcattttat aattcctctt tctcgttgta atatgtgtgc
    58621 taacacgggc ttttttatat aagaaaacga taagcgcttt ctggaagacc gtaaagattc
    58681 tttaattcct cgattttttt aggatattga tcattatctt ctttataaag agaaacaatg
    58741 agattagcag caaagcaatt agcttcgctt tcagatttgc ttctagatgt tcttgttgat
    58801 acataatagc tggataagcc acgatgaaaa atagcgtgac ctaattcgtg agcgcaaatg
    58861 tagaatcttt cctcagagtc tcgcagttca tcatttaaaa agattatcgc acgatctcta
    58921 atttcttgaa actgcccctt gggattctcg ataaaaggaa cgtattgaat tttaatgccc
    58981 atcttttcac aaatataaaa aggattagcg gactggtatt tccgcttcaa ctcctcgact
    59041 aaattaatcg tatccatctc cataagctca catctttttg cctttttctt tgtcttcttt
    59101 cacaatatcc cagaaagtcg ctatcaggat atcttttacg cgctgtattt gttcgggtgt
    59161 caatgtttcc ccaccataag acatattaac atttgagtct agtagtttat caagttcaac
    59221 cacttcctct tttgtagccc atttgggaac attattattt cccaataaat aatcagttgt
    59281 gacaccaaaa taatcagcaa ctttctttaa gttctcagat tttggcgagg ctttatccca
    59341 tcttcttatt tgtccattag agatgcccac ctgtctttct acttctgcta tagtcacatg
    59401 cttttcgtct gctaattctt taatcttagt aactaaactc attattatca acctttcaaa
    59461 gctgaaaaga aaataaatag cttaaaagtt atatttttgg ttgacaatta gcttttaagc
    59521 tagtatattt aattcgtaag ctaaattgtt agctaaataa gagcaacaaa aaactctact
    59581 aatttaaaac attctctcgg tcgccaaact tagaaatgtt attttagagg ctttttataa
    59641 gtcttattta actatgtatt cataatagct taaaagctaa taggtgtcaa cgatttagct
    59701 aattttttag cttacaaatt attttttaga aaggagctat ttttatgtct gagaatttag
    59761 acttaaaaat tcgagcggag atgagaaaaa gaagaatgac tttcaaagaa ctagctgcgc
    59821 ttgttggtat ttcaggagct tatttatcag atatcctaaa cggcaatcgt gatggtaaaa
    59881 aagctcaaga acacatagaa actgtaaaaa aaatattagg tattcaatag gaggaacagc
    59941 taatgcaata tctagaagcg aaaatcccag ttccagaagg ctatgtaatt atctctcaag
    60001 tggattacga ggagttaaaa aaagctgatg atactggtag atggatgacg ttgccagaag
    60061 tgctagaacg gattaacaga aaatatgatt ggtttacttc tagagtttta aagaacccaa
    60121 gatatagaaa tattatcgat atcgagaaaa acaaaaatgg atttgtctat tatccagttg
    60181 aaggaagaga cacatatcta tttttaagaa gtaaaacact tgaattttta gaaacaaatt
    60241 tttcggaaat cttaaggagg caagcggatg ggaaaattta atagagcgct agtgttcagc
    60301 gcaccgctaa tcatctacgc tttaggactt tggggaagca ggcaagcgtt gataggaacg
    60361 attgtttaca tggtttggat ttttatgggg cttgatgaag ctgaagctga gtacagagcg
    60421 aaaaagccaa ccgagggggc tgactaaaaa tgaatagaaa agagaaacta gaatgtatat
    60481 tactattact cagtttaatt ctttcactaa tttctctatt gggaagtttg tatttttgat
    60541 atcaacaatt ttgtggattt gggttctatt tagagtaaat atcatttttg tttggtgatt
    60601 aaggagttta ttaaaattaa ttttccctac ttcaaatgca aggtaacaag atatagcact
    60661 tttaggagga atatttagcg gtacagcttc agagtatatt ctattatcat cgactgatcc
    60721 tcctttagca attaatttct taaatggagt agctgaccat ctgcggttta agttagcgga
    60781 tgaaagttct aaattaacta acatagctgg ttctgttgaa tagttagaaa tgattacttt
    60841 tgtataaatc atatctgcag cgaagtaaga agcattaagt tcaacttcta gttgagggcg
    60901 cattcctttt atttttatcc ctgttaaaaa cgtactcaat ataaaactta ttattgacat
    60961 ccattgaaaa attgttaagt gaaaaaaatt caaaataaac accaccagtt tttaactaaa
    61021 ttataccaaa aaggagagaa gaaataatgc aagaattagt aattttgaaa aataaagaag
    61081 ctgtgactac gagcttacaa gtggcagaaa gcttcgagaa aaaacatcaa catgttttaa
    61141 gagatattga tgcactaaaa aaagatgtgt ccaattttgg acagatgttt gtagaaggta
    61201 atgaaccaga ttcatatggc agaaatcgac gagttttctt cattagtaga gatggatttt
    61261 tcttgctggc tatggggttt acaggaaaga aagctatcta cttcaaacaa aaatacattg
    61321 aagcattcaa cgaaatggaa gatgttattc gcaagaatac tgttcctcaa acaattgaag
    61381 atatgatgat ctatcaatta gaagaaatga aagatgttaa aaaagatgtt tccatgctta
    61441 aagatactat gcgaattagc ggacaacaag agtttgaaat taagcaaaaa ggaaatatga
    61501 aagttatggg agttctaggg ggaaaagaaa gccgagctta tgaagaaatc agcaaaaaag
    61561 tattctcaaa attttggtct gaatttaaac gtaccttttc aatcccaaga tatggcgagt
    61621 tacctcgtaa gagattcgat gatgctgttt catttattga aatgtggttg ccagaaactg
    61681 cgatccgtat ggaaattgat caactgaaca gacaacagag actttttggt gatgacaatg
    61741 aatagagctg aagcgctaag aatagggacg gcaattgcta attgctggtg gaaatactat
    61801 aaaccaatca tcctaagcca acaacatatt gacaagcaaa aagcatggca acaaataaaa
    61861 aagtgactcc gccggcaagc aaagagtcac aaagaaaaca catcataagg agattttagc
    61921 atatggaaaa agaactttcc actctagatc aatatttgat tgatcctgat tggggcaagc
    61981 cgaaaattga ggaaacaagt ggtcgaaaaa tcaggcgaaa tcttttgacg aatgaagaac
    62041 tagcttgtga tcaagatgat ttaggtaacc ttgtaactat ttgagatcat gtttatctta
    62101 tccatttatc gaagcattcg aataaacctg aatatattta cgtcatcgaa gatggcttga
    62161 ttgatgcatt agaagagtac gaaagggata acttgatcga tatctcttat tacggaccag
    62221 gtaagaaata cattgctgaa ttggaggcag aatttgatga gtgaaaacaa agggacaacg
    62281 aattttgaaa aactttttag tcgcaagtta aataaaattc tcaagaaaaa aggaaatttt
    62341 gattatttat cttgggctca cgcatgggag attatgaaaa agaatgatcc acaggcaaca
    62401 gtaactatta atgagtacaa acactacaga gttgtttctg gaactcatca agactttctt
    62461 gttgaggaat acaaaccttt tcttatggat gaaacaggga cttatgtatc tgtctcagta
    62521 acggttaaag gacacacgga aaccgagtta tttcctgttt tagattatcg aaaccaacca
    62581 gttgttaaac caaatgcaat gcaaatcaat aactcattga agcgatgctt tgtgaaagca
    62641 ttggctctac acggactggg attatatgta tttcaagggg aagatattcc aacaccacct
    62701 agaatcgata cgaagaaatt aaacatgcta gagacgattc tagaagcttt caatgagcag
    62761 atgggtaaag atatgaccaa aaccttaatc gaatatgtta atgagcagac agataaatta
    62821 gggctcttag ctgataacgt tgaaactatt gaacagttaa gctatgagca atgtgccttg
    62881 atggagcgag caatagcagc taagagaaaa gaattagata agaagtgata tgagtgttta
    62941 aaccattaat cgattcatat tcagcggttc tgaaaaagtt caaaggaaaa gacataggtg
    63001 caaccatcaa tgaggaagtg aacattgatc gactaaagac gatgtatgac ggctacgatg
    63061 gtgatcgagt tattgaaatt cgttttattg atcctagacg tttcacagta cagcaacgaa
    63121 acttcatcta tgcactcata ggcgatattt tcatcgatac aggcatgcca acggacttct
    63181 ggaaggaatt cttttacttc cgctttgaag gtgtcacagg gcgcaaaata agcctcaaag
    63241 atgaatcgaa tacgactgtg agtgatgcta acgtcttagc aaatatcatc ttagatttca
    63301 tctttgaaca tcatattcct ttcaaagaag gctatgagat tttaccagcg aatcaagaat
    63361 attacttcta caaatgcatc acaaaaagag tctgttgcat ctgtggcaaa acaggagctg
    63421 atatcgatca ctttgacaaa gcgctaggaa gacgaaagcg caaagaagtt gatcattcag
    63481 agtacacatt tgcagcactc tgcagaatcc atcacacgga gaaacacaag ataggtgtga
    63541 tcaatttcaa aaataaatat caaatcaaag ggatcaagtt aaaccaggaa acaattaaga
    63601 aacttagaat aggaggataa aaaatattgg ctgacaacaa acgatactac tatttaaaac
    63661 taaaagagaa ctttttcgat agcgacgaga tggttctttt agaaagtatg ccagatggat
    63721 acatttattc taatattctt ctcaaacttt atttaagaag tctgaaacat gaaggcaaac
    63781 taatgtttaa tgacaggatt ccattcaatt ctacaatgct tgcgactatt acaagacact
    63841 ctgtgggagt tgtagaaaaa gcagtacaaa tatttcgtga tttacaactt attgaggtat
    63901 tagataacgg agcaatttat atgtctgata tacaaagttt tattgggaaa tcttcaactg
    63961 aagctgatag gaagagaaaa tacagaaaag aaattgagga agcaaaacag aatttaataa
    64021 caagtggaca aatgtcggac aaatgtccgg acaaaactac accagagtta gagatagagt
    64081 tagagaaaga tatagagtta gagaaagata tagagaatgt aacgccttcg aaaaaatcga
    64141 aggctaagcc cgtccgtcat aaatacggag agtataaaaa tgttcttttg tcagatgagc
    64201 agatggagaa actcaaaata gaattcccta atgactatca agaacgaata gaacggctat
    64261 ctgagtattg tgaatcatct ggtaagactt ataaaaacta tttggcaact attcgaagtt
    64321 gggcaaggaa agaaaaaagt gagcctaaga atgcaagtgg tgcatacaag cgcacaggaa
    64381 gacgagagaa gcttcctgaa tgggcaatcg accaagaagc ctatctcaag aaaaaagcgc
    64441 tagaacgagc taatagacaa tcaaaagcac cattttaaga ggtggaaaat tgaaaatcga
    64501 ttatctagaa ctaattaatg aaatagcaaa gtataaaact ggtgaggaaa tagaaatcct
    64561 gagagacgta tatgatcaac tcgaagaagc tggaatcgaa ggaattaata atgatcgttc
    64621 gagttggagt aaactcagat actatttcgc actctatatc gatacaacac aattaagaaa
    64681 tttagcttat acaaaattac tatttgttga ttgcgttaaa ggattgcaaa aacatcttag
    64741 tgaacttgag caggtgtaat cagatggatc taaaaacatt tacagcacag atcgaactaa
    64801 tgcatcaaga agctttaaga caaagcgcct cgtacgaaga caagtggctc aacacgttcc
    64861 atggtggacg tgagagcgca cttgatcaag tactcaaatt attgaaaggg gaacgtcggg
    64921 atggataaga aagcggcaat gaaacgaatc atcgaactga cacattctga gaattggcaa
    64981 gaagacaaag aaatagttac agaagtccaa aagctcggta aatcaatgtg gactgaaaag
    65041 cccaaacgga gaacgccgag aaagattgca atttggcatg gtgatcgaat tctagtaaca
    65101 ggtactgctg aacagttatc tgaaattact ggtctgagca aaaacatcat ctgggataga
    65161 gcaaggagct tatggattga ttcaaaagga cgacaattta ggtatgtgga ggagaaaaaa
    65221 tgaacgaact aatcacaaaa gtagagcagt gggctaaaga caagggactg gatcaagcag
    65281 atccaaaagc acagtttttg aaagtagctg aggaattcgg ggaaatcgct tcagcaatgg
    65341 caagaagtaa tgatgagcta tttaaagata gcgtaggaga cgtaatcgtc acgttgatta
    65401 tcctttccat gcaaaaaggg acaaacgtac aagagtgttt agaaatggca tacaacgaaa
    65461 tcaaagggcg cacaggaaaa atggtagatg gtgtattcgt gaagtcgagt gatttggagg
    65521 acagcaaatg ataggtttaa caatattttg gtgtgcgatt ggtggtttac tagcatttct
    65581 aggatactac ctcatctgtg aaagtagaaa aggaagaaaa tatacagtga caggtattgt
    65641 cctgttaatt atcggaattc tagttgcagt tggagcagaa ctgaatcttt atgtaaatgg
    65701 tacacaagaa gatttggtgc gatttatgtt ttggatgaag aattaggagg aaaaaaatga
    65761 acgaaaacaa attaatcaaa ttaggtgtag caggagcagt aatcgtaggt attggagtta
    65821 tcggaggatt taagttcttc gaaaaaatcg ataatggata tgtgggtgtg cgctattcaa
    65881 tgaacggcgg tatcaaagat gaagcactga cgcaaggtgt gaaatttgta gggattgaca
    65941 aagtgatcca atatccaatt cgcttgcaaa ctatccaatc aaaaaatatt tcagtatcta
    66001 caagcgacgg caaaaagaca acgattgata tcaaatatga ctacaaagtt gattcaacta
    66061 aagcagcaaa aatgtacaag gaatttggga atatcacttc ggaagatatc gaaagtggat
    66121 ggttaaaatc taagcttcaa aaggtcgctc gtgaagttta tgcgaaatat agtctgcttg
    66181 atgtcctttc aggagattcc tctaaagttg aagctgaggt attaacgaac tttgctaaat
    66241 cagttgaatc taaagggttt gaagtcgaag acgtaacact tggtgttcca gatgtcgata
    66301 aagaaacaca aaaatcaatc gatgcgatca ttcgagctgg tcaagaaaat gaaaaagcga
    66361 agctagatgc agaaactgca aaaactcaag ctgatagtga agcttacaag aaaacaaaag
    66421 ctgcagaagc agaggcagaa tctaatcgca aagtcgccga atcagtaaca gacaatttga
    66481 ttcgttatga agaagctcaa gctcgcaaaa agcatggatg ggtaacagta aatggagcag
    66541 atactgtagt tacggatgaa gcaggcaaat aatatgggat tctttatggc taaaattctc
    66601 ttgttcttag gtttagtagg agcagcatat ctcgtgtatg cgctcctttc ccaaactgat
    66661 gacaaagaag atgacaacaa cgatgaaatg aaattttagg aggagaaata atggatctca
    66721 ttacacaata cagtgatatc atcctcaaga aaatcatggc aaagattcag aaagataaaa
    66781 aagcaaaaga acgagcggaa ttagttaagt tggaaatggc tgaaacagga gtaggagtgc
    66841 gaagtagcag gcattggaaa gcagcagcaa acattgaatt ttattacaac gaaattcaaa
    66901 aagggttcga tcagatgcgt gagctggatc ggcaaacaaa ttggagcaag aaacttcatc
    66961 aagatcgttt caaatttgta gagaagtata aagaaatatt agaagagtat ttgaggagga
    67021 cagcgaatga taaaaaagct cattcaattc agcatggatt tatatgatat cgaatcagga
    67081 gcaacagtat ctgtggagtc tgatcattta atcataagtt ttgctgacga acgtcaaatt
    67141 atcatatggg tagttgacga tatgctatat ccagaaattg tacatgattt tgaagaatca
    67201 aaagcggttg agtttgaaat agtgaaaaaa gtaatggaat tgattgaaaa atacgaggag
    67261 gacagcaaat gataccgaag tttagagcgt gggataagcg agaaaacaca atgagagatg
    67321 tagctgtctt acattttact aaaaacggca aaacaaactt tattgaatat tggataaatc
    67381 ctaccgaatt gaaatcatat cacgtgcgaa acatcgacct catgcaatcc acaggaatga
    67441 aagataagaa tggtgtggag atatttgaag gggatgtagt aattacatca aaaggagcga
    67501 ttggatatgt tgcgtatctt caacaagaag ccggctttgt agttgtacta aagaaaagtg
    67561 attatagatt aggccatagg aatactggcg aaagttatga tgtagcaact gctcatgaag
    67621 tcatcggaaa tatatacgag aatagcgagt tattggaggt agagtgatta tcttagctac
    67681 tgactacatc gattctttaa aagatgaaaa tgggaatgtc ccagcattgc taaattgtgg
    67741 aattaaaagc aagaatagaa tcattttgtt acggatatcg gctgatttag caaaatatct
    67801 ttatctgagc aagacagcag tatattacac tgcggctaca cgttatcagt acaagggaaa
    67861 aacaatcagt caggattatt atgatcgttt aatcagtcct gacatgcatg gaaaatcaaa
    67921 atcagcgatc aagttatttg gcgcaataga gatatatgcc gatgattttc caaatttatg
    67981 gttgaaggag gaagcggaat gaaatacgaa ataccactaa gtgaagcggg cattcaagca
    68041 attatcaatg gtcgggaggt taataaaaaa cttcctgatg gtactgaatt agtcatcaga
    68101 caaagttatt tgaaagatat ggcagctcca gtattaattg atcgttttaa cgtgactgat
    68161 tctgtggtag agaaccactt gaaagaattt cgatcaagta taaacgacac tttcagatta
    68221 gggagttgat tgacaatgaa caccagacac cgcagagtag caaaactaag aaaacaggaa
    68281 ctgaatgtac taaagacaaa gtttgaaaaa gaatatggaa tttcagcaga agaaacatat
    68341 aaagtggcaa gtcagtttgt tgctgatgcg agtgagacta ttcgtaagtt tgggatttcg
    68401 atattaaatg atgatcgtaa atgggaggca gaaagatgaa actaaaagac ggattttaca
    68461 ctgatgctta tggaattggt ggtttgatga tggatctacc aactaagaat cctataaagc
    68521 aagaggaatc agaaattaaa gtcggtgaca tggttcgctg cgaagcagaa gggttcatct
    68581 atccatttcg tggatatgta gagcatctct ataatcactc agcgatcatt cgtattgaaa
    68641 acacaatgga atgcgataag tggttagcga aaagcaaaga gaatttagca gtggtgagat
    68701 tggtggatat ggaggttata aacaatggaa ttaaaaattg acaaggtaac gtttgaagaa
    68761 ccagcatttc aagaaatgga tgaacgaatt gcagaattgg tcgagaaaaa acaagatgaa
    68821 ttgattgctt tgctagaaaa gaaataccaa tttccgaaat atatgaacaa aatgcaagca
    68881 gcaaaatatc ttggtgtaag ttacaacacg atgatggata agtacgtacc agctggtttg
    68941 aaaatgggta tcgttaacgg cgttattcgt atcagcaaag aagaatgtga tcgttttatg
    69001 aaagaacatc aaaaataaaa taaaaaaacg tttagcccct tagctaaacg cacaattata
    69061 atttacctga cagttaatta taacaaaatt gcggaggttg aggaatggcg gaatgaaaaa
    69121 gacaataaaa acagaagaag catatattga agtatttgac acaccagcat gctaagtcga
    69181 gaagtgtaac tcggcaaata aaaaaagccg gatcgctccg actgatgtaa taaacccaac
    69241 aagtttatta tatcacataa aggagcggtt tgacttgatg caattgttac gagaggtaga
    69301 tttcaaacag acaagatgca atgcgagaga tgtgctgaag aattttcgac gcttagagcg
    69361 gatggcaggt cgctctttga tagatattaa gtcgccgatt attacggata tgccgaaggc
    69421 accgaagcac ggcaataagg cagaggacgc gattattcag atgatggata tagaagcaga
    69481 gagagatgcg attctagcgg ctttgatggc tcttagtctg attagccgtc agatactcta
    69541 ttatagcttt tgtgacgtaa acaagcactc taattatgaa atagggcaat tgatacgagg
    69601 atacggagag aagaatgtag agaagctgaa atctatcgcg ctgatcgaat ttgctgaagc
    69661 atacaaaaaa ggcgtattag ttcagtatcg ttgattttgt agggtttttg tagggatagt
    69721 gtagggtttt tgagtggttt aacgtgatat tatgatagtg tcgaaagatt agtgataggt
    69781 ctaagacaaa ataataataa aaggaacatc gttttattat tgtttcacaa ttaagcttcg
    69841 atagacagca gcggaaatat taagaataag gatgtgaatt ttaactcctt ctaaattgtt
    69901 cttattatct atcatccgtt gctgtctatt aatttatgta ttggagggaa aacgaatgga
    69961 taaagaaatc aaagtaactg tcaaattaga tttgactgaa ctaaaagaac tgctcaacaa
    70021 ggctagtgac caagtcgaac agttacaaga aactttagat gaaattgcta ttgtgaataa
    70081 agctgaaagt gaaaattcta gtttttttgt aaaagcaaat tggaacattg atttaccaga
    70141 aggggatatc aacaatccgg tagcagaacc tataaagtat aatccttcca aggcaaagct
    70201 tgataaggta cattagaaag aaattttacg atatctgttc taccgtgata cttcattttc
    70261 ccatgcgact gttcagctaa gataataggt cttgggaaat ttcttgggat gctacttcta
    70321 acttgttctc tatgagaaga agagatcaca ccgtttttca caacaacaac tgtaaaagtt
    70381 acgccctgtt ctttggtaat agcagcagtt attttcatat attcaccacc tataatttat
    70441 ttcagcggac cactcgctga taaataaaat tatacgctta gtatttattt tcacaatatt
    70501 aatttgtcac tgtggcggaa agggtagacg ctaagcatgc gtgctaggtc aatgcttcgg
    70561 caaccatgca atgttcgatt cattgccagt gactttggca accgagggtt ggaaatgggc
    70621 gctccaagta cacgagcaag gcgaggtcga tagtaatcga tggaatcggt gtaggttgct
    70681 tgatagaact ataactgcat ctcgtttatg aggtgtagtt tttacatatt agatcactct
    70741 ttgagtggtc tttttatttt gaaaggagtt ttatctatga atgaaaaaca attaagcgag
    70801 ttatttaaat tgaatgaatc aaatcaaact gcagaggcaa cattctatga agctcaaaaa
    70861 agcttagcgt taatcgcaaa acaagctaag tatttctatg accagcttat tctacaaggg
    70921 tttaatgaag gacaggctat ggaatttatg atgcgaacct tttctgccag taaccaacag
    70981 aaagagtgat acataatgag aaactactgg tatatatcgc taactaatga atatcctcga
    71041 accattgatg attgttcagt gcgtgttgtg cgttctgtac aaatcaaaaa gaagtactcc
    71101 atcattgaaa tgaccagaga agctacacca aatgagatcg ataagtacaa tcttcgttac
    71161 tgtggccatg gatattggaa agacgaatat attcaacaaa acattgagag gtacatcaaa
    71221 tgaatgataa ctatgattac atcaagttga ttgaaaagat aagagcagaa aaagatatgg
    71281 acgaactagc taacttattc atgaacatca ttagtttggt ggggttaaag atggatgaag
    71341 tagcggcact aaattatttc atcgctgagc aaacaattag agcagagcac aatgctaagt
    71401 tcttgaaaga taggttagat ctagatgtaa aaggattagg cgttgaaggg atattcaaag
    71461 tgcaagaagc cttagtgaat gtttatgtcg aaaagatgca atagcattaa caagtaatta
    71521 ttggatgttt tcaggaggga aactatgaaa ttaaaagatt atatcaggga agggtataac
    71581 attgtaacta caccaaatct agcttacaaa attcaagaag attatcccaa tgttttagtg
    71641 tttactgata gagctttaga tgccattcct atagggaagt tattagtaga tcgttattat
    71701 agcaacaatc cagctgttct tagtgctaag ccacttcaaa acgcttatgc tattgaacgc
    71761 tttacttgcg agtttactgg atatgagacg gtagtaccaa tgacaggcga gacaggaaga
    71821 aaagtaattc aacagatcaa aaagaggatt gctgaattga cgttagatga tggaagtaat
    71881 acgaaccttc tagaaatcaa actaagagat actgactcag taccagaagt ttattataaa
    71941 ggtcaacgaa tggatgagat gccgataggt cttgtcgata ttacttatca ttggcatacg
    72001 gaagaatatg aatgccaagt accaaaagga gctaacgaca tcactattga atattatgat
    72061 tcacataata acaagtactt agatagaaaa atcattgggc acaagagaga tatgtaaatg
    72121 attgatgttt caactaaaca agcaagagct aggttctatg gatcaactga gtggaggaaa
    72181 cttagaagtc aatgcttaga gcgagatcat tatgagtgcc aatggtgtaa agcagagggt
    72241 agactaacaa ctcaacatga ttcaattctt gaagtggatc atataaagga gctggagtat
    72301 catccggatt tagctctaga tataaacaac ctaagaacct tatgcaaaga ttgccataac
    72361 aaaaggcaca accgtatgaa atatcgtggc caacaaaaga aaagaaagtg ggatgatgaa
    72421 tggtggtaag aaaaacagca aacagagatg atgtcaaacg agcagaagca atcgctatgg
    72481 ttgataaggc tattgataag ttggttctat ttaagagtca gctcattgaa gaaacaacaa
    72541 ctgtagagga tatatctatc aacaatagac taataggtaa cgctaatgaa gtaacaggga
    72601 catttaatat taatgtagac attgattata ccttgagtcc atttgcacat attgtagaaa
    72661 gcaacgagca agacggctga taaatcagta taaagcgaag atatatagag tgaaataccc
    72721 ccggtcaaaa gattttgaga agaaataaaa tttttgggaa ccggtggatg gggttaattc
    72781 tgcaaatgca acgtatttat tttacccctc ccccctccgc cgccccttta gtaaatatag
    72841 aaggaaggtg attggtttga attctaagtt ggttggcacg agaatgaaac aaaaaagaat
    72901 tgaaaaagga ttgacacagg ctgatgtagc aacgaaaagt ggtatttcta gtaggtatta
    72961 tggaagtatt gaaaatggga aaaattcccc tagtatcgaa acgttaaact caatttccat
    73021 cgtcattgga tgcagtttac atttcttact caatgatcgc atggacgaca tggaaaaacg
    73081 cgtagagcta gaaaagaaac gtctgcagaa gatattcgat aaaattcctc atgacaaact
    73141 taatttagtt gaagggctga tcattcaggc agcaaggtta cgtgtcttgt tggatgataa
    73201 ctggaaggac atcattgaaa acggggagta cgagaaattt aaacaaagcg agaaccaaat
    73261 tgcttatgat agaaagcgtc ctatagttga aaattatgat aatcgagata aaacttatca
    73321 agccatcgtc aaacaactca ccgatttatt accgcaaggc acaagagcgg acaagaaaag
    73381 taagttactc ggtaggaaat aaaaatgctt tttaaccagc acgttgatca atatattcgt
    73441 aaatggaaat ctggtgagtt aatccttaac gaaaaaagga tacaactttt aaaactaata
    73501 gaaaaagaaa tattacctcg cgacgacatt tattacttcg acgaggagca aataaataat
    73561 tatatcgagt ttagtcaagc atggtatttt gagttagatg aatgggagaa atttatttct
    73621 gcattcattt ttttgtttta taaagaagat gacgaagttg tttttgatga atttgttatt
    73681 aatatggggc gtggcggggg taaaaatggc tttatttcaa cattggcaaa ttattttgtc
    73741 agttcgcttc acgggattga ttactatgat gtttcaattg tagctaatag tgagaaacaa
    73801 gcaaaaagaa gttttcaaga atgctatcga gtaatcaata aaaaaggaaa tgaagattta
    73861 aaagaagagt ttgaagcgta taaaagcagt ctaaccggtt tagagacaca gtctgttttt
    73921 gagtacaaaa ctagtaatgc aagctctcaa gatggcggtc gagaaggtgc agtaatatac
    73981 gacgaatacc acgaaatgga aaacacagat attgtagatg tgttttctgg tggactgggg
    74041 aaagttgatc acggacggca atttttcatt ggtactaagg ggtttgttcg tgaaggttac
    74101 tttgatatta aatatagaga gtgtgaagat attttaaatg gtttgtcaga gttcaagggt
    74161 gtatttccgt acatatgcga actggatgcc attgaagaaa tggatgaccc caaaaattgg
    74221 ccgaaagcaa acccggcact gcaaccaccg ttgaataaac gtgggaaacg tctgtttaac
    74281 gaagtcatga aaaagtacaa aaagttagct aaagaacctt ctggacgctc ggcatttgtt
    74341 actaaacgaa tgaattttct tgaagacaat atggaaaact ctgttgcttc aagagaagaa
    74401 ataatggcaa caaatcgtcc attttttgaa ctagatacgg taccgattgg atctctcgat
    74461 ttcggtagtg ttcgagattt tgctacttgc ggtttgctat ttaaaaatcg aaagaaatcg
    74521 gaatacgcgt ttaaatcatt tacgtttgca atgaaaaatt tttgcgacgt tcattatgga
    74581 tactcgttga aagagcaatt ggttggcagt gaaaaacggg caccaataaa aacttgggaa
    74641 aaaatggggc tgatgaaagt tattgacgag ccatctttaa atcctaagta tattgttgat
    74701 tggtttattc aagctagaga agaatatgga gtgagagtaa ttgtcgtgga taactataag
    74761 gcagatattt tagggcctat gcttgaaaaa gaaggatttg aagtagttcg actaaaaaga
    74821 ccatctagtt tacatccatt attagctcct cgtatagaag atggatttgc aaatcacaaa
    74881 tttatttttg gagataatcc gttaatgcgt tggtttacta ataatgtgta cgtaaaggaa
    74941 acgcaagcag gcaaacaatt cttaaaaaaa gaggaagtca agcgtaaaac tgatgggttc
    75001 caagcatttg tacacgcatt gtacaaagct acagaattag atgaacagat tgattacgat
    75061 gatgcttttg atatgttgga tgagattgaa ttttaaggta tacttttctt tacaaagggg
    75121 tgctttcatg aggataaaag gaaaaaacat atcttgggta ttttacatgt tggggatttt
    75181 agcttttaca tttgtggcaa taaaactatc agaaattatt attccaaatg acagtgtagt
    75241 ttcaaagaat ttggttttag aaagagctaa actaattatt tcaattttag gaccagcatt
    75301 aacactaatt gtttttgttc gaacaattca aactcaatta gaatcttcaa aaaactt
//
LOCUS       DADVXM010000005        74440 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.005, whole genome shotgun sequence.
ACCESSION   DADVXM010000005 DADVXM010000000
VERSION     DADVXM010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 74440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.005"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(159..443)
                     /locus_tag="KB927_000388"
     CDS             complement(159..443)
                     /locus_tag="KB927_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839335.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(461..1351)
                     /locus_tag="KB927_000389"
     CDS             complement(461..1351)
                     /locus_tag="KB927_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBB6839336.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1371..1589)
                     /locus_tag="KB927_000390"
     CDS             complement(1371..1589)
                     /locus_tag="KB927_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBB6839337.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1559..3259)
                     /locus_tag="KB927_000391"
     CDS             complement(1559..3259)
                     /locus_tag="KB927_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBB6839338.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3526..4299
                     /locus_tag="KB927_000392"
     CDS             3526..4299
                     /locus_tag="KB927_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839339.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4380..4949)
                     /gene="thiT"
                     /locus_tag="KB927_000393"
     CDS             complement(4380..4949)
                     /gene="thiT"
                     /locus_tag="KB927_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBB6839340.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5015..5117)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5123..6094)
                     /locus_tag="KB927_000394"
     CDS             complement(5123..6094)
                     /locus_tag="KB927_000394"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBB6839341.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6188..7561)
                     /gene="glmU"
                     /locus_tag="KB927_000395"
     CDS             complement(6188..7561)
                     /gene="glmU"
                     /locus_tag="KB927_000395"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBB6839342.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8064..8882)
                     /gene="purR"
                     /locus_tag="KB927_000396"
     CDS             complement(8064..8882)
                     /gene="purR"
                     /locus_tag="KB927_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBB6839343.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9049..9873)
                     /locus_tag="KB927_000397"
     CDS             complement(9049..9873)
                     /locus_tag="KB927_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6839344.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9846..10526)
                     /locus_tag="KB927_000398"
     CDS             complement(9846..10526)
                     /locus_tag="KB927_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6839345.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10549..11487)
                     /locus_tag="KB927_000399"
     CDS             complement(10549..11487)
                     /locus_tag="KB927_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBB6839346.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11732..12595)
                     /locus_tag="KB927_000400"
     CDS             complement(11732..12595)
                     /locus_tag="KB927_000400"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBB6839347.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(12737..15310)
                     /gene="mprF"
                     /locus_tag="KB927_000401"
     CDS             complement(12737..15310)
                     /gene="mprF"
                     /locus_tag="KB927_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBB6839348.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15451..16257
                     /gene="proC"
                     /locus_tag="KB927_000402"
     CDS             15451..16257
                     /gene="proC"
                     /locus_tag="KB927_000402"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBB6839349.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16336..17892)
                     /gene="rny"
                     /locus_tag="KB927_000403"
     CDS             complement(16336..17892)
                     /gene="rny"
                     /locus_tag="KB927_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBB6839350.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18303..19352)
                     /gene="recA"
                     /locus_tag="KB927_000404"
     CDS             complement(18303..19352)
                     /gene="recA"
                     /locus_tag="KB927_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBB6839351.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19461..20702)
                     /locus_tag="KB927_000405"
     CDS             complement(19461..20702)
                     /locus_tag="KB927_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBB6839352.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20942..21520)
                     /gene="pgsA"
                     /locus_tag="KB927_000406"
     CDS             complement(20942..21520)
                     /gene="pgsA"
                     /locus_tag="KB927_000406"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBB6839353.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21729..22652)
                     /locus_tag="KB927_000407"
     CDS             complement(21729..22652)
                     /locus_tag="KB927_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6839354.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23391..24677)
                     /locus_tag="KB927_000408"
     CDS             complement(23391..24677)
                     /locus_tag="KB927_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBB6839355.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24670..25938)
                     /locus_tag="KB927_000409"
     CDS             complement(24670..25938)
                     /locus_tag="KB927_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBB6839356.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26190..26651
                     /gene="mscL"
                     /locus_tag="KB927_000410"
     CDS             26190..26651
                     /gene="mscL"
                     /locus_tag="KB927_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBB6839357.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26710..27156)
                     /locus_tag="KB927_000411"
     CDS             complement(26710..27156)
                     /locus_tag="KB927_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6839358.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(27249..27494)
                     /locus_tag="KB927_000412"
     CDS             complement(27249..27494)
                     /locus_tag="KB927_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBB6839359.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(27609..28187)
                     /locus_tag="KB927_000413"
     CDS             complement(27609..28187)
                     /locus_tag="KB927_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6839360.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(28264..28794)
                     /locus_tag="KB927_000414"
     CDS             complement(28264..28794)
                     /locus_tag="KB927_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBB6839361.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(28798..29658)
                     /gene="rlmB"
                     /locus_tag="KB927_000415"
     CDS             complement(28798..29658)
                     /gene="rlmB"
                     /locus_tag="KB927_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBB6839362.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(29651..30046)
                     /locus_tag="KB927_000416"
     CDS             complement(29651..30046)
                     /locus_tag="KB927_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBB6839363.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(30043..31455)
                     /locus_tag="KB927_000417"
     CDS             complement(30043..31455)
                     /locus_tag="KB927_000417"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBB6839364.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(31452..31988)
                     /gene="cysE"
                     /locus_tag="KB927_000418"
     CDS             complement(31452..31988)
                     /gene="cysE"
                     /locus_tag="KB927_000418"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBB6839365.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(32074..32313)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(32310..33770)
                     /locus_tag="KB927_000419"
     CDS             complement(32310..33770)
                     /locus_tag="KB927_000419"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBB6839366.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(33940..35097)
                     /locus_tag="KB927_000420"
     CDS             complement(33940..35097)
                     /locus_tag="KB927_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBB6839367.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(35131..36501)
                     /gene="radA"
                     /locus_tag="KB927_000421"
     CDS             complement(35131..36501)
                     /gene="radA"
                     /locus_tag="KB927_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBB6839368.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(36564..37091)
                     /locus_tag="KB927_000422"
     CDS             complement(36564..37091)
                     /locus_tag="KB927_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBB6839369.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            37321..38127
                     /gene="proB"
                     /locus_tag="KB927_000423"
     CDS             37321..38127
                     /gene="proB"
                     /locus_tag="KB927_000423"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBB6839370.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            38124..39371
                     /locus_tag="KB927_000424"
     CDS             38124..39371
                     /locus_tag="KB927_000424"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBB6839371.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            39447..39791
                     /locus_tag="KB927_000425"
     CDS             39447..39791
                     /locus_tag="KB927_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839372.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(39908..40234)
                     /locus_tag="KB927_000426"
     CDS             complement(39908..40234)
                     /locus_tag="KB927_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839373.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(40607..41808)
                     /locus_tag="KB927_000427"
                     /pseudo
     CDS             complement(40607..41808)
                     /locus_tag="KB927_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            41925..42440
                     /locus_tag="KB927_000428"
     CDS             41925..42440
                     /locus_tag="KB927_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6839374.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(42639..43085)
                     /locus_tag="KB927_000429"
     CDS             complement(42639..43085)
                     /locus_tag="KB927_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBB6839375.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(43132..44610)
                     /gene="msr(C)"
                     /locus_tag="KB927_000430"
     CDS             complement(43132..44610)
                     /gene="msr(C)"
                     /locus_tag="KB927_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBB6839376.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(44964..45593)
                     /locus_tag="KB927_000431"
     CDS             complement(44964..45593)
                     /locus_tag="KB927_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6839377.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(45577..46041)
                     /locus_tag="KB927_000432"
     CDS             complement(45577..46041)
                     /locus_tag="KB927_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6839378.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(46528..47796)
                     /locus_tag="KB927_000433"
     CDS             complement(46528..47796)
                     /locus_tag="KB927_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBB6839379.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(48027..48764)
                     /locus_tag="KB927_000434"
     CDS             complement(48027..48764)
                     /locus_tag="KB927_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6839380.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(48831..49400)
                     /locus_tag="KB927_000435"
     CDS             complement(48831..49400)
                     /locus_tag="KB927_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBB6839381.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            49528..50400
                     /locus_tag="KB927_000436"
     CDS             49528..50400
                     /locus_tag="KB927_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6839382.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            50742..51614
                     /locus_tag="KB927_000437"
     CDS             50742..51614
                     /locus_tag="KB927_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6839383.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            51611..53569
                     /locus_tag="KB927_000438"
     CDS             51611..53569
                     /locus_tag="KB927_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6839384.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(53820..54671)
                     /locus_tag="KB927_000439"
     CDS             complement(53820..54671)
                     /locus_tag="KB927_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6839385.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            54794..55261
                     /locus_tag="KB927_000440"
     CDS             54794..55261
                     /locus_tag="KB927_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBB6839386.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(55524..56006)
                     /locus_tag="KB927_000441"
     CDS             complement(55524..56006)
                     /locus_tag="KB927_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBB6839387.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(56106..56969)
                     /locus_tag="KB927_000442"
     CDS             complement(56106..56969)
                     /locus_tag="KB927_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6839388.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            57567..58415
                     /locus_tag="KB927_000443"
     CDS             57567..58415
                     /locus_tag="KB927_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839389.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(58586..58927)
                     /locus_tag="KB927_000444"
     CDS             complement(58586..58927)
                     /locus_tag="KB927_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HBB6839390.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            59013..59720
                     /locus_tag="KB927_000445"
     CDS             59013..59720
                     /locus_tag="KB927_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBB6839391.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            59707..60030
                     /locus_tag="KB927_000446"
     CDS             59707..60030
                     /locus_tag="KB927_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBB6839392.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(60119..61156)
                     /locus_tag="KB927_000447"
     CDS             complement(60119..61156)
                     /locus_tag="KB927_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6839393.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(61603..62586)
                     /locus_tag="KB927_000448"
     CDS             complement(61603..62586)
                     /locus_tag="KB927_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBB6839394.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(63002..63772)
                     /locus_tag="KB927_000449"
     CDS             complement(63002..63772)
                     /locus_tag="KB927_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6839395.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(63765..64700)
                     /locus_tag="KB927_000450"
     CDS             complement(63765..64700)
                     /locus_tag="KB927_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6839396.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(65294..66943)
                     /locus_tag="KB927_000451"
     CDS             complement(65294..66943)
                     /locus_tag="KB927_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBB6839397.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(67138..68034)
                     /locus_tag="KB927_000452"
     CDS             complement(67138..68034)
                     /locus_tag="KB927_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6839398.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(68027..68707)
                     /locus_tag="KB927_000453"
     CDS             complement(68027..68707)
                     /locus_tag="KB927_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6839399.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(68708..69490)
                     /locus_tag="KB927_000454"
     CDS             complement(68708..69490)
                     /locus_tag="KB927_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6839400.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(69483..70400)
                     /locus_tag="KB927_000455"
     CDS             complement(69483..70400)
                     /locus_tag="KB927_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6839401.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(70403..70687)
                     /locus_tag="KB927_000456"
     CDS             complement(70403..70687)
                     /locus_tag="KB927_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839402.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(71388..72008)
                     /locus_tag="KB927_000457"
     CDS             complement(71388..72008)
                     /locus_tag="KB927_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839403.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            complement(72089..72499)
                     /locus_tag="KB927_000458"
     CDS             complement(72089..72499)
                     /locus_tag="KB927_000458"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839404.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            72529..73707
                     /locus_tag="KB927_000459"
                     /pseudo
     CDS             72529..73707
                     /locus_tag="KB927_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT        21520 a        15817 c        13087 g        24016 t
ORIGIN      
        1 ataccgagaa aatggttttt gaacatcact tattcaaaat aaaaaaagat tgtgacacga
       61 attttgtcac aacctttaaa tgtattccta gagcaaagaa gctaagcgaa gaaatccaat
      121 tctgattatt tattgtattt ctttgttcag catccttgct aaaagcccat attggacaaa
      181 gtattcacta cacccatgat ctcatctttt cgagaacgtg ctttttctgt cggatcttct
      241 acctcttctg tgtcaattcg aacaataaat ttccgattca tcgtcacgta agcaccgtcg
      301 ttgatcaaaa taaacagttc gttctcatta tagtctgcac aggcatcttt ccatacgtca
      361 aagccgtttt tttcagaagg gatatcccgt ttaaccacag tttttccact taattcgtgg
      421 aacgttacgt cataatattt cattatctct acctctttcg tcattcaata ttttgtactt
      481 gttctctgat tttttctaag atcgtcttag actggacgac ttgattttta atttcgattg
      541 catttgattt ggaaccgatc gtgttgattt cccgattcat ttcttggatc aggaaatcta
      601 attcccgacc tacaggacat tgtgcttcga taagttcatc tagtttttgt acatggatcg
      661 ccagacgatc cagttcctcg tgaatatctc cgcgttccaa caagatggct agctccgtca
      721 acaaccgttg ctcatcgact ttcgctccaa gaaattcctc cagctttttt tgatacctta
      781 tttgaaattc cttttcatag atttctacaa aactatcgag tttttttagt acttctttga
      841 attcttcagt attctttttc aacactaaag ctaaagcttg accttctttt tctcgactcg
      901 cctcaataga atcaagtgcg cttttcaatg tatctagagc taactgtgcc aattcttcca
      961 tgctctcttc cggtttttct tctaccgtta cgaagttttc gtccagcgcg aagcgttccg
     1021 ccatccgact aattgacact tgattttgac taccgtatcg ttgttgaatt ccgtctgtca
     1081 attgagtgat aagtgaatca atcaattccc agttgatgac gatctgtttt tcgtttttgc
     1141 caatataagc tagattcaca aatacttcga ttcgaccgcg gcttaactgc tgtttaataa
     1201 gctgacgaaa atcgttttca acaaagttca ggattttagg acttcgtatt tgaacatcta
     1261 gaaaacgctg gttgacactt tttatttcaa tatctaactg atacgctttt gtttcgcgga
     1321 tggctttgcc aaaaccagtc atacttttca ttcgacaggg tccttcctca ttacatattt
     1381 tctattgctt tttgcagttg ttcaaactct tcgttcgtca atgtcaggcc tttccccatt
     1441 ttttcatggt ctggcgccca atctcgaaga tcgaattttg gcgggcgacc attccagctg
     1501 actaggttca gttctttacg ccaccccttg ttgttttctg acaatatagc gatttcttct
     1561 acgatttcat atgaaaattc ttgtgccatg gttgttcctc cttgagataa tataaatata
     1621 ggatcagtaa tgtgtcaact ggttgcttaa gcaattcatg ctgcaaacga tccttgcgtt
     1681 ttccttgtag cagataatca aaataaacag ttttcgtgcg ctcattttgt attttttgct
     1741 ggtattttcg ataccttcgc cattcttcag tacttaattg accaatttgt gccaataaat
     1801 catccggcat actttttata tcttgttggc agatcatttg aatcatcatg tctacttgat
     1861 agatttcatt gggcagtaaa aaatgttttt ttgctaaaag ttctagcatc gccaatccgc
     1921 atgtctctgg tacgaccctg ttcttatata aattacgcag tttttgccaa aattttatgc
     1981 ttttgaaaaa agataattct aactgaattt cttttgttaa gtaagacaaa aatcctcgcc
     2041 agtatgttct tgcaggttta acagaatgaa atgtatacca gttcccatag taatagccta
     2101 atcgtttttt catttccaga tagcctaatt gtaaatttaa ttggttcctt tggctatcaa
     2161 aaagcagaaa gctgcctagt gtccacaatg tttgacattt ccaatggata aaaatgtctg
     2221 gcatacgaat ttttttcgct gggcctggcc cttgcacatc tacgacaaat gcctctgttg
     2281 ctcctttgtt aatcgcaata tcaataggta ttttgttgcg atacccaccg tctgcatatt
     2341 tattttttcc gatctttcga taagccatag cgggataaaa tgaagcagag gcgagtatcc
     2401 aatctggtat ttcttctgtt tttgtctgtt ggatatcagt cactacttcc gctagttctg
     2461 gcagtttagt agacaccgta tataaacgta ttttgggatt atgtttgagt aaggacaaat
     2521 ccaaattgtc tttgaccatc ttttccaatg gagcagaaga aaccccgcct tcaattagtg
     2581 ctgttttcgt catttggcgt ctttctcgat agaagcgttc acgaaggtct tcaactgcag
     2641 ccatttctgg taacgcaagc acttgtcttg tcgacagctt tttccataaa ttcacagctt
     2701 ttttcatatc tccttgtaaa atcaatgcgc cgttcaacgc acctaccgag gtacctgtga
     2761 taatctcaaa gttgatatca tgttccttca gcgcctgcca cacaccaatc tgataagcac
     2821 cgtgcgctcc tcctccacct aaaacaagtg ctgtatgata gaccagcttt ttatttaatt
     2881 gtgtggttcc ttgatagccg tttttatgaa aaatacgcaa ccattcttct gatagaggag
     2941 attgaaataa aaaacaacag ttttctttaa taaaaaaacg agcgcaagct tccatatacc
     3001 gaaaaaattt tttccattca aaagtttcac cttcaatcaa cagattatta aaaataacat
     3061 ctcctctact tttagcaata gtaaaataga cggtatattt tttcgatact gctttaaaag
     3121 cacattgctt ttttgcagaa cgccaaaaag cgtctctact ttcttgatga ctttgaaaaa
     3181 atggaagggg ttgttttgct tgctggatag gcgaatacag cgacattttc tgtgaaaagt
     3241 aaactttttt tatctccatc gcgctctcct ttttcttcaa gtataccagt acgtcataaa
     3301 aaggtcatga gtctcgtatt cgactttgta gattccataa gaaaacaatt cataaaacct
     3361 cctttaaata aaaaaataca aaaatcacaa aaattaattg aaaatgagag tgttttcaat
     3421 gaaaacgtga ttttgtaatg gaattttaaa ataaaagaaa caagcttttt taatgcaaat
     3481 gttgtaaaat aaaagagatt aagaggaaat aagaggagga acatgatgac tgagtcagtt
     3541 tatgtacata ttgataccac aagtaatgct gttttaacaa aagggctgac tgctactgac
     3601 tttgcaaaca gtatcgtgca ttttcctcaa aacttgctct tgcttgatcc atctgcttct
     3661 gctggagaat atgaatccca tacagggctg aaagtaatcc gtggtacaga aaatattcag
     3721 cgtttctttt cctcttctcg taacaggcgt ggattcgatg aattgaagtg gatcgacttt
     3781 actgatttaa cgatgctgaa agaattgaca cctttagaaa tttcagaatt attatatttt
     3841 ggtcatatga aaacacatct tcattcgccg tttttttata aactacagaa taattttgta
     3901 tacttcgatc ttaatgatca gctgaatcgg atttattatc gctatttaga tgaattttat
     3961 aggatttttg ctagtaaatt aagttcgatc ttgtcagata agatcaatgt aaaaaaatct
     4021 tttttcaaaa aagaaacacc tgttgaaaaa atcagtgtgg aattattgaa agaaatgcgt
     4081 aatttgatgc aggaagggat cattttttct tttgatcaag ttggtttgat cgatggtaaa
     4141 tatcgtatcc caatctatgt gattgaagat tatatttgga aattaaaagg cacccggtat
     4201 cgagaagagg aaatcatcgc tactttaatc tactctgtca ccgatcgaca ctggcaattg
     4261 gtagaagatg ccgatctttc ttatctgcca ttgaagtaga tctatttctt atcaaaaaat
     4321 aaaaaggaaa caagaaacta ggacatgatt ctgtctcaag tttcttgctt cttttttatt
     4381 tacagctcct gtcgtttatc tggcacaaaa atcgaaggag tcgtttgttg gatccctaat
     4441 aaaacgatga tcgttacaat agctgtactc aacccgctgg caccattcat tacgaaagaa
     4501 aagagccaag gattcatccc ccatagtgca tacgctcccc agaaaaccac tcctgcaata
     4561 aaatgccaaa aatatctgga aagtgcgcca atcaatgcac caaacacgat gctttttcta
     4621 atttgtttcg tattatcgtc tacatagcct ttttggacat ttgaagccat gagccctgct
     4681 gcgcctgcaa aagtataggc aatcgggtac tcaatcaaca cttgaacgac acttaaataa
     4741 taaacttgtc ccaacggaaa atgtaggatg ccccaaatga aacctgccag catccctgcc
     4801 tttgtccctc ttcttaacgc aaaaagagtc aatggaatct gccctaatga aatagaaaaa
     4861 ctgctgccga tctggatcgg aatcaacgac aacaccatcg ctaacgctgc aacaatcgtt
     4921 ccttctaccc aaactctatt ttttcccata aaaaaacttc ctcctttgaa taaaaaagtc
     4981 acaaaggagg aagcagcttt cgaaaatagt caaacagctg tttattcaca attcctacgc
     5041 tcgcataacc gatacaggta cgaagggttt agaaatagat tcaatctcag cccaattgga
     5101 ctcccctttg tgagtttatt tattatttat tttttgtttc aaacaatgga ctaactggtt
     5161 tgttttcatg gatacgtttg attgcatctc ccattagtcc gccaacactt acttcatcga
     5221 ttttgtcgat tttacgatct tctggaagat agatcgagtc tgtaacaact agacgctcga
     5281 tagctgaatc ttctattctt tgtaaagcag ggccggataa tactggatgt gtacatgaag
     5341 catacacact agttgcacca gcttctttca aagcattggc agccaatgtg atcgtacctg
     5401 ctgtatcgat catatcatcg atcagtacac aagttttgcc tttgacttgt ccaatgatat
     5461 tcattacttc tgcaacattt gcttttggac ggcgtttgtc tatgatcgca atcggagatt
     5521 tcaaaaattc cgctaattta cgtgcccgtg tgacaccacc atggtctggt gaaacaacga
     5581 caacatcatc gcctttgatt cctttttcta agaaataatt ggcaataagt ggcgcaccca
     5641 tcaaatgatc gactggaata tcaaagaaac cttggatttg aactgcatga aggtccaaag
     5701 tcagcattct tgttgcacca gctttttgaa tcatgtttgc tactaatttc gctgtgattg
     5761 gttcccgtgc acgtgcttta cggtcttgac gcgcatagcc ataataaggc atgactacgt
     5821 tgattgtttt tgcacttgct cgtttcagtg cgtcaatcat gatcagcaac tccatcaagt
     5881 tatcattgac tgggctgctc gttgattgaa taacatagac atgcgatcca cgaatacttt
     5941 cttcaatgtt tacttgaatt tctccatcac taaattgagt aacagatgat tttcctaact
     6001 cgacgccgac tgctgctgca attttctctg ctaatgggcg attggaattt aacgcaaaaa
     6061 tttttaatct tgggtcaaag taatgttttg acatggggac ctccactttc tttttcacaa
     6121 ctctagaatt ctacctaata aatagtagtc atatttttta aataaatcaa gtgattttgc
     6181 aaaagtctta gtttagataa gggagttttt ttgcatatcc ttctttattg acttgtcttg
     6241 ctctcgcaat tgccagcgca tattctggaa tattgtctgt aattgttgac ccggcagcaa
     6301 tcgaactgtt tttagctacc tcgacaggtc cgatgatatt cgtgctagaa ccaataaagc
     6361 tgtggtcgcc gacagtcgta tgatgtttgt tctttccatc atagttgacg aagacaacac
     6421 cacatccgac attgatttct tctcccagcg tagcatcacc aacataagtc aagtgaccga
     6481 ctttagttcc tttgccgatt tgagcatttt tcacttccac aaagtttccg atatggacgt
     6541 tttcgccaat ttcagctttt ggtcgtaaat gtgcataagg tcccacatct gcatgtttct
     6601 tgacatggct gctttcaatg actgagtttt caatgacgac gtgatcctca atcctactgt
     6661 ctacgatttt tgaatgtgac ccgatgacac aatcagaacc aatgactgta tttccttgga
     6721 tttgtacacc tgcttcgatc aatgtgtctg gaccgatttc tacgcctgca tcgatgtatg
     6781 tcgttgctga atcgacaaag cttacgccat tgaccatatg catctggtta attcgctttc
     6841 tcatgatctc atttgcttta gctaacgcga tccgatcatt gactcccatt gattcttcaa
     6901 aatcatccgt ttgataagca gcaactgtat ggccttcttc ttttaagatt tcgatgatat
     6961 ctgttagata gtattcacct tgagcattgt ttgttccaac tttgcttaac gcatcgaaca
     7021 aagcttcgtt gtcaaaacag taagttcctg tattgatttc ttgtacaaga gcttcttctg
     7081 gtgttgcatc tttttgttcc acgatttttt ctacgatccc aatatggtca cggatgattc
     7141 gtccatatcc tgttgggttt tctgcttgtg ccgtcaagat cgttgcactt gcattttttc
     7201 cttggtgata ttcaaaaaga ttgttcagcg tttcagtagt caataatggt gtatcgccac
     7261 tgataactaa cgttgttcct ttttttcctt ccaagaaaga agcagcttgc aaaacagcat
     7321 gtcctgttcc caattgttct gcttgtaacg catatttact gcgttctcct agttgtgctt
     7381 taacttgttc tgctccgtgt ccaacgatcg taatcacttc atctggtttc gtttcactga
     7441 cccgattaat gatatgttct accataggtt taccagaaac gggatgtaaa actttatata
     7501 attttgactt catgcgggta cctttccctg ccgccaaaat aattgcataa cgtgcgtcca
     7561 actgcgtcac tcctaaatat agtttgctga tttcagttta tcccagtata cccatttttt
     7621 caacaaaaca agtgattttc ttttatccca gcgttttctg gataaaaaaa tagatagacc
     7681 ataacgggcc tatctatttg gtaaccggtg ctctcctgcc aactcctcgg tcacaagtca
     7741 cactactcat aaaacatgaa aagctgtttt ttgaaatcgt ttcttgtgac ttagagttaa
     7801 acggtaggct tacaacctct tcattaaacg tttttcaatc agctgacctt cggtattagc
     7861 tcaataaacg gcaaaatatg aggagcaatt tttccgttta ttgagctaat actcaggaca
     7921 ggacgctgat ttcacaacct ctagataaac ggtgttcaaa agccagtttc tcggtattaa
     7981 gccaaattta tgaaaaaatg tggaaagcca ttttcacaaa atttttctta ctactcgaaa
     8041 ctaagcagct ttttcacaac ctcttattct gaaaaataat ttcctggcac aaccgtaata
     8101 tttttcgttt gagtatctac atctttgaca taaagcagtg acgtataatc atcgatggcg
     8161 cgatgaccgt tgaattttga ttcggcaaat acagtgatgc caacaagttc tgattcgaat
     8221 tcttcaatca agctcttcat tccgttgact gttccgccgc ctttcatgaa atcatccact
     8281 acaaggacac gtgaaccacg tttcaaactt ctcttagaca gttccatctt ttcaattctt
     8341 tcagaagatc cagacacata gttgacactt actgttgatc cttctgttat ttttgagtcc
     8401 cggcgtacaa taacgaatgg cgcattcaga taataggaca cagcttgggc aataggtacg
     8461 ccttttgtgg ctacagtcat tacagcatcg attttttcac caaggtattt agaagcaatg
     8521 attcttccaa cttgacgcag cagttcaggt tctcctaaca aatcagagag ataaacatat
     8581 cctcctggaa gcagacggtc ttgttctgat agacgttctg ctagagattc aatatatttt
     8641 ttcgcctctt catatgaaat ttcagggatg aacaatacac cacctgcagc acccgggatt
     8701 gtttccaagg ttccataccc tcgttcttta aatgttttct tgatgattcc caaatcttca
     8761 ctgatagaag atttagcaga ttcataacgt tcggcaaagc ttgttaagga aatcaattca
     8821 tgcgggtgat tcaataaata ctgtgtcatg tcaactagac gttcactgcg acgtactttc
     8881 acctattcca actcctttta agaaatttta tcgttttaca ttatataagt ttttcttcaa
     8941 aaattcgagc attttatgaa aaaataagaa aatagttcgg tatttattaa aataaaaaga
     9001 agcctataaa aaatttttcg tttttataag gcttcttttc tttataattt agttattttt
     9061 tcttctgaag gcaaccaata ttcgtttgat gatatttaca atcaggaaca aagcaataaa
     9121 gactaatgtg attgttgctc ctggaggtgt atctagataa aacgagctag ttagtcctga
     9181 cagcatccct agaaatccta cacaaacact gatagcaatc acgacattga agcttttgcc
     9241 taatcgcata ccgattgctg cgggaagaac catgattgcg gatatcaaaa gtgcaccggc
     9301 aatcgggatc atcacagcaa tagccacacc agtaatcaca ttgaacatca tcgacatcaa
     9361 atgaacgggt agcccatcca cgtgggcggt atcttcatca aaagtcagaa catacatcgg
     9421 ccgtttgaat aaaaagaaca atataccgat ggcaacgaat aagattccta aaaagatgac
     9481 ttgctcccat gtaatggtca cgatcgaacc aaacagatag gattggatac ttgttgctga
     9541 attccctccg ctcaaattca tcaatactaa cgctagcgcc aaaccaccag ccattaaaat
     9601 ggcaatggag atttctgaat aggttcggta gatcgttcgc agatactcca atatcacagc
     9661 tgctaataca acgactagca tggtcgtaag tgtaggatta aggttcaaaa agaatcctaa
     9721 cgctacccct gctaaagaga catgagaaag cgtatcagcc atcagcgatt gtcttctgat
     9781 cactaaaaac acacctagca tcggggcgat tccggcaatg aagatagcgg caagaaacgc
     9841 tcttctcatg aattcatatg aaagcaacgc cattgagaat cctcctttct caccagtcgg
     9901 atctgtctgt ccgcatactg tttgatatct tcatgatcat gggtgatcat tagaactgat
     9961 ttcccatgga catgcgcact atgtcggaga agacgataaa attcatttct ggattcttca
    10021 tccatacctg ttgttggttc atcaagaaca aataagtcag ggtcagtagc aaaaatacgc
    10081 gctaaactga ttcgctgctt ttgtccgcca gacaattcac ctattcgccg atttcgcata
    10141 tcccacatcc ctacagcttc taaagcacgc tgtacatgtt gatgatcttt ttcagagaga
    10201 cgcttgaacc agcggcctct tggatatctt cctgaacgga ctaattcgat caccgtacta
    10261 ggaaaacctg cattgaaaga tgcaacttgt tgaggaatat aaccgatact taattttttt
    10321 ccttcttgat ttttctcagc aatctttatc attccttttg aaggtttcag taatcctaac
    10381 gatgctttca ccaaggttga cttggctgct ccattttctc cagttaaaat gacaaattca
    10441 cccgcatcta catgataaga gacatcttct agtacaggtt catcatcata gtaaaaggtc
    10501 aaatcagata tttcgatata acgcacctta caacctccat tctaaaactt aattgatact
    10561 ttcttttaaa gctttcagat ttttttccat gacagaaata taattttcgc ctgctttgat
    10621 ttgttcatta gtcaagcttt ctaaaggatt caacacttct agcttcactc ctgtttcatt
    10681 cgacaatgtc tcagctacct tcgaagaggc attttcttca aaataaatca ctttgatgtt
    10741 gtttttcttc acaaattctt ttagctcagc taagcgactt ggtgtgggtt cctgatctgg
    10801 tgaaacgccc gaaatcgcta cttgttttaa gtcgtattga ttcgctaaat aagcaaaagc
    10861 agcatgctga gtgacaaatg tgcggtttgt tgcatctttt agctcatcgg agtatttttg
    10921 atccagtgct tcaagctttt tgatataagc atcggcattc ttcgtaaaag tttccttttt
    10981 atctggatat ttttcgccta attcttcagc aatcgttctg acttctttta tagctaatac
    11041 cggatcgagc caaacatgtg gatcgtattc atgtgaatga ccatgccctt cttctgattc
    11101 ttcatgttcg tctgcttctt gcgattctaa acggtcgatt cctttagctg cttcgatcat
    11161 caaggtctgt ttgctatcca ctgaatcctt taacgaatcc acaaaaaatt ccatgtctga
    11221 actattatac acgaaaacat ctgcatcgga aatttctgct ctttcttttg cacttggttc
    11281 gaaatcatgc ggctccgttc cagcagggat caaaagtttc acgtttcctt catcccctac
    11341 gatctctttt gtaaaatcat acatcggata aaaagtcgta acgatcgtca aatcctcttt
    11401 tttgtctgct tccttgttcg tatttccaca tgctgcaaac agtaaagcac ctatcattac
    11461 cgtagctgtc aaaagatatt ttttcattta tatgctcctt tcaatgaaca aatcggaatt
    11521 ttacgattta ttaacgtgaa ctaatgtatc aaaataaaaa aacacagtca atagaaatcc
    11581 atcaatttct gatttaagca tgtatattct tgattaaatc gtaaaatgga tgagttgctg
    11641 ctcatatcta gccatttcac tacaataaaa aactgaagaa taccatttta ggattcctca
    11701 gtttttcatc acctatttta cttcttatat tttattgcag ggttcgtact aaataaactt
    11761 cctcacaaaa accttttaac ccattatata ctctctgcgc tcttgaataa tgttgacaca
    11821 aggcaaaaac ggttggtccg cttccactca tcaatgcagc atctgctccg tacttgatca
    11881 tacgctcttt gatttgatgg atgactggat gccgctttcc cgttatatct tctaaactgt
    11941 ttcccatttt tttgatcatc tgctgataat cttgctctcg gatggcttca gcaagtccgt
    12001 ggatgtcttg atgttggatg gcttgcgtat ctacttctct aaacactgta cgtgtagaga
    12061 cactcattct tggtttgacc aacacaaccc agcactgtgg catagaaggt aatacttgga
    12121 tttcttcccc tttgccaccg acaaatgccg tacttccgta gacacagtaa ggaacatctg
    12181 taccgacttc caaaccgatt tctgccagtt cttctaacga acagcccaga ttccataatt
    12241 ggttgatccc tcttagagca gctgcacagt ctgtacttcc tccgcctaat ccagctgcta
    12301 ctggaatatt cttcttaaca aagatcttga caccggtttt gatattgtat ttatttttta
    12361 gcaataaagc agcttgataa acattgttcc gttcatctac cggtaaaaat gctttatttg
    12421 tttctacaat gattttgtct tctgttattt cttcaaaaaa tagatgatct gccaagtcta
    12481 cgctcgacat caccatttcc aactcatgat acccatcttg ccgtctatat aatacatcca
    12541 gtcctaaatt tatcttggct ggcgcttttt caatcaattc catcctctca cccattcgaa
    12601 aagtctaagt cgcaagtatt ctatcatagg gaaaaataaa agtatagctt atgtctgcct
    12661 agtggttgat tttgtcatcg tttcaacagc tttcacagaa ttttctcttc ataatccaaa
    12721 caagttctag tgattcttat aattctgtga gcacttcttc tgccaaactc ggaacatttc
    12781 ctttttcttt tcctatcaga ctgagtagct gcatggtagc aaatccgaaa ttacttcctt
    12841 tcctataagc aaaataacgt ccttcccaat gatcgacata ttttaatttc ttttcataag
    12901 cagactggaa ggaatagaaa aaattaccat aattatatac gatatgcatg actttttctt
    12961 gaaagaaaga aaaatctgtt tctccaacat tagctaatgg agctaagcct agattggctt
    13021 ccgagtagcc cattttctcg tatacaataa acagattggc taacagatag tcagctaatt
    13081 cctcagattc tttaggtaag acccgcaaca aatcatatcc cgcctgcttc ttcgtcatcg
    13141 gctgagcggt gatgaagcca acgacttttt gatctttacg gacaataccg acaccgctag
    13201 ataatacata tgatttatca aatcgtccca cagagaagta tttttctcgt gcaccttgaa
    13261 gccatttttg tgaaacttca tttacagctt gatgtaattc ttccggcagt tgatcgtacc
    13321 aagtaaaatg gtatccttct ttcatcaaac gttgatattc aagttgctga ctcagccgag
    13381 acaagtcttc tgttgctaga tcaacaatcc ctgcttcacc tactttcgtg aagtgaaaac
    13441 ccaattcatg aagcatcact acgtagcttt ctgatatctt ataaaacgca agctgatagc
    13501 ctaaacaatc tgcttgtttc ataaactgat tcgttgctgc ccgcatcatt ttaggattgc
    13561 caactggatc tcctaaaaca aagcatttgt ttcctttgat ctgataacca aaaacgactt
    13621 gatcttggtc gtcttcttgg taataaaaat aactgtaacc tgacaagcga agctgatggc
    13681 ttgtagctgt gcctccgtat gtttccaata aacggtcaaa acggtctttt tcgtactcac
    13741 tgccaagctt cgtagtatct tcagctaaat attgataaag cgccactaaa gctagcaatg
    13801 agatgcccaa accaataagc cctgagaacc acacatcatc tgaaggaaac aaaataaaat
    13861 gatttcctgt tattcgaccg actaaaaagc gtccgctgtg atagcctgca attgcgtaaa
    13921 cgataaacaa aaagccgaac aagctagcat caaagattat agctccccaa gaataaacga
    13981 attttgttcg ataaaattct tttctggata accacacagc taacagaatc aagacatata
    14041 ccaatatcaa ctgccaagat aacgtacgtg tgattgtatt taaaatacca aaagatagta
    14101 aagcaatcgt aggcagaaat gcctttttga cttttactga aagtgctcta gcaaggccga
    14161 gtaataaaaa gccaaccaat agattcactg tctgatctaa aaaattgaat gagaacggca
    14221 ataatacttg aaatagccga ctgattgcag acagattagt gattgttgat agaagtacca
    14281 tcatgatccc cgcaaaatag acagcactta cgagcacgat atgcgcaacc ttttggaaaa
    14341 acagtcgcgg aatgttatct aaaaatcgat tgattttgac tcctgtatgt gtgatgaaca
    14401 atagaagtcc cgtcataaaa ggtagaacat aataaaacaa ccgataatat aatagccaaa
    14461 ctactgctac atcttgccga acaggcaatt gactcattcc taagatcatc aaaacgtcaa
    14521 aagtccccat tccacctggg accatcgtca gcattcctat caatgtagca atcatgaaca
    14581 taggatagat cgaaagcatc gaaatatcta ttctcatcaa cttgccgatg atcaaaaata
    14641 ccgcaagggc tcccgtccat tgtccaaagg atgccagtag cagaccaagc aagccttttg
    14701 gataaaactc gaagaacaat gtctttctct ttagataagc aaaaaagaaa atgactggtg
    14761 ctaaaaaact accgccgaaa agccagatcc aatagcttcg aaaaatactt tctgactgaa
    14821 taaaaaagac atcaataaat gtaagaaacg accatacaga caaaccagtc agcataaata
    14881 gtgcgacttt tgatacagtg gctaaaacca tttttctatt tgtctgcttt ccataaaaac
    14941 tagcccgcag acttgctcct accacaccac caaaaccggc gagattgttg atcgtgtttg
    15001 ttacccacgc agcaagaaga aactcttttc tttccatttt tggttttcct tgtttttcta
    15061 agactctgat cgtcacccaa tcatacaaca acatcggagt gacacccagc agtccagcca
    15121 gaatcatgag caggatcgtc atgcggcttt gttgtcccat cctttgccaa atatcttgcc
    15181 aactcatgcc attagcaata tttgcgactt gatttgccac aaagactaac acggagccga
    15241 aaaaaatcag ttttaaaatc agactatgtt cctttatcca ttgcagcatc aagtatcgtt
    15301 tatttttcac attttcccat tcctaacttg tatacttttg tgtcataccc caatgttatc
    15361 ttatttattt taatttttcc actttagacc tgttctttgc ttgcgatgat agaaaaagaa
    15421 agatatccta atgctaaagg agaggataac atgaaagtag gatttatcgg cacagggaat
    15481 atggcacaag ctattattga tggtttatta aaaaaaggaa cagtctcgaa agaagaggtg
    15541 ttcgtttcca gtggacattt tgaaaatgca caaaaatttg ctgctgaaac tggcgtccat
    15601 gcatgcaaaa gtaatcagga agttgcatca caatcagata tcgttctttt agccgtgaaa
    15661 ccaaaaatca ttgaaaaagt attggaagaa ctaagagaat atagccagaa agtcttattc
    15721 atttctattg cttcaggaaa atcattaaca gatttagaaa cagcgcttga agatcctcag
    15781 gcctccatcg tacgtgtgat gccgaatgtc aatgtcagcg taggagcagg cgtttctgcg
    15841 atttgcaaaa atgaagctgc cacggaggaa cagcttcagc aagctacgat gatttttgaa
    15901 gcaatcggca gcgtctatcc tttagcagaa tcagatttca gtacattcat tggccttgct
    15961 ggcagctcac ccgcattcgt ttacatgctg atcgatgcga tgggacggac tggtgtactg
    16021 aatggtttgt ccaaacagac agccactgag attgctgcaa aagcaattat gggttcttgt
    16081 caaaaattcc tttcaagtga taaaaatcca tgggaacttg tagaccaagt ttcttctcct
    16141 ggcggtacaa ctgttgcagg tgtagttgcc ttagaagaag caggattcat cccagcaatc
    16201 atcaaaggaa tcaatacgac gatcgagaaa gatcttgaga tgttgaataa aaaataatga
    16261 tagcaatgtt ttttcgtgcc ttacaaaaaa agaagagctg tggcttttgc cgcggctctt
    16321 cttttgtatt ttttattatt tagcataatc agttgcacga gtttcccgaa taacgattac
    16381 tttgatgtgt ccaggataat ccagttcttc ttcgattcgt ttacgaatat cacgtactaa
    16441 acgaacagcg tctaaatccg agatttcttc tggcttgacc attacccgaa cttcgcgtcc
    16501 agcttgaact gcgtaacttg attctacacc ggcgaagctg ttcgaaatat tttccagact
    16561 tcttaaacga cggatgtagt tttctaatga ttcacttcgc gcaccaggtc ttgctgctga
    16621 gagcgcatct gctgcagcta caaggacaga gataacagaa gtagcttcca catctccatg
    16681 atgagaagcg atcgcgttga ttactactgg gttttctttg tacttggcag ctaattccgc
    16741 accgatctca acgtgagatc cttcaatctc atggtcaagt gctttcccaa tatcatggag
    16801 caacccggca cgttttgcta attggatatc ttcgccaagc tctgctgcta agataccagc
    16861 taattttgca acctcgaccg aatgcttcaa gacgttttgt ccataactag ttctgaatcg
    16921 cagacgtccg atgatcttga ttagatctgg atgaagtgta tgagcaccga cttcaaacgc
    16981 tgcctcttcc ccgtattcgc gaatacgttc atccatttct ttacgagatt tctcgaccat
    17041 ttcttcgata cgcgctggat ggattcgtcc atcttgtatc agtttttcca aggtcatccg
    17101 tgcgatttct cttcggattg gatcgaatcc ggaaagaaca actgcttccg gtgtatcatc
    17161 gatgattaaa tcgataccag tcagcgtctc aagcgttcga atattacgac cttctcgtcc
    17221 aatgatacga cctttcattt catcattcgg aagggtaacg actgaaacag tcgtttctga
    17281 aacttgatct gctgcgcagc gttgaatcgc taatgataat aagtttttcg ctttgcgatc
    17341 tgcttcttct ttggcacgct gttcagattc ttttaccatt agagttaact catgattcag
    17401 ctcttcttca gtcgatttca tgatgacatc tcgtgcgtcc tcttttgata aaccagcaat
    17461 tttttctagt tctttttgtt gatcttcaat cattttttca acgtcttttt ctcgctcttc
    17521 aattaattgc tgttttgaac taagtgcttc ttctttactt tcaagtgagt tctcgcgttt
    17581 ttctaacgag tcatctttac gattcagcgt ttgttcgcgt tgaatcaaac gattctcttg
    17641 agattttaat tctaacttac tttctctcag ctcactttca acttcagaac ggtatttctg
    17701 attttcttcc ttagcttcta acaatgcttc tttttttaga gtttctgctt ctttttttgc
    17761 actatcgatg attccagcag ctgatgattg tgcaccagct atttctttct cgtgacgtga
    17821 ctttgcgacc ataaacccta aaccaagacc gacaattaaa ccgatgatag cgaggagaat
    17881 gttgaatacc ataaaatcca cctccatact atctttttca tttttatcat ctatacagct
    17941 tctatgataa attattctaa actcgtcaat atgcatcttc gcatatatgt gtacaaaaaa
    18001 catgcacaac tttattctaa tgtttgtacc ccgtagtgtc aactttaaat aaacaaagaa
    18061 acggctttct acttattcat taaacgatgg tttttaaaat aaatgacact agtttcatat
    18121 aggtaaacct ttaaattgag aaacttttct attaaattat tctttgtaga tgaacagata
    18181 tttttatttt atgtacccac tcgtataatt aaataactca cgatttcttt attcaataaa
    18241 aaaacggcag gtcaaggaga gtacctactc ttcagaccag ccgtttttgt ttatcataat
    18301 ttttattctt ctactaaagg caattcttct tgtccttttt catcttctgg gacagcgact
    18361 tcttcaccaa taccataagc tgctctaact agagcagaaa cttctgccat catttcagga
    18421 tgattagcca tatagatttt agcgttttcc cgtccttgac caatccgatc ttctttataa
    18481 gaataccaag caccgctttt atcaacaatg tctttttcta ctgccatgtc tagaagttct
    18541 ccttcttgtg agatccctaa accatacatg acatctactt cagcgatttt gaaaggaggt
    18601 gctactttgt tttttacgac tttgatcttt gtacggttac caacaatatc tgtaccttgt
    18661 ttcaattgtt ctgcacgacg tacttccaaa cggatcgttg cgtagaattt caatgcgcgt
    18721 cctccaggag tgatttctgg attcccaaac atcacgccta ctttttcacg gatttggttg
    18781 atgaaaatag cgattgtttt tgttttgttg atcgaaccag agagtttacg caatgcttga
    18841 gacatcaaac gtgcttgtaa cccgacatgt gagtcaccca tttcgccgtc gatttctgct
    18901 cgtggaacta aagcagcaac tgaatcgact actacgatat ctacagcccc acttgatact
    18961 aaagcatcag cgatctctag accttgttct cctgtgtcag gctgtgaaag aagtagttca
    19021 tcgatattca cacctaattt ttgtgcatat tgcggatcta acgcatgctc agcatcaatg
    19081 aaagcggccg ttccgccatt tttttgtact tctgcaatag cgtgtagtgc aactgttgtt
    19141 ttacctgaac tttcaggtcc atatacttcg atgatacgtc cacgggggta accgccgaca
    19201 cctaaagcga catctaacgc aagagagcca cttggaattg tagagatttg ttggtcgatt
    19261 ttttcgccca atttcataat agagccttta ccatagctct tttcaatttt tttcagtgca
    19321 gcatctaagg ctgctttacg atcatctgcc aatacgataa tcctccttat atttacaaat
    19381 cagagcaaca tttcattatc cttatcatat cttttttagt gaaaaaaagc aagaaaaaac
    19441 cgaacaaata ttcgcattta tcattttctt aaaagctgtt ttctcaaaag atcaaatcct
    19501 tgcataaccg cattatatct gatagcagca cgatctctgg caaagtgata tttttccgaa
    19561 accacgccgt ctttagatga aatagcgatc catactgttc ctgcagattg accttctaac
    19621 gtgtccggtc cagccactcc ggtgaaagct acactgtaat ctgttcttgc tatctcacgt
    19681 gcttgaatgg ccatctgctc cacacattct ttgctgactg ttccatattc tgctaatagc
    19741 tccggatcaa tctccagaaa accagctttt gtttggagcg agtaggtaac gaatccgcct
    19801 ggaaatactt cagatacacc agcaatgtcg cctaatgcgg cttggaaggc gccggctgtc
    19861 aaactttccg ctgctgttac agtctgcttg ttttctttca gtagttccac tacgactttt
    19921 gctagcgaat tatcatcgcc gtatccataa aaatattccc ctactcgttc ttggattttt
    19981 tcttctaatg ctaaaagagc ttgattccct gcctgaacat catttgtttt cactgtcagt
    20041 cgtaatgtca cttcatttgg tttggcatat ggtgcgatcg ttggattgat ctgtgtctca
    20101 atcagatctt ttagctcagt gaccagtcgc gattcaccaa tcccataaaa gcgcaaaact
    20161 ttagaaatta gtttttcttc agaaggaaaa cgttcctcta gtaaaggacg tacttgttcc
    20221 acaaacattg gtttcaactc attaggcgga ccgggaagaa ggatatacgc atgtgtatct
    20281 gtttgataaa aagtccctaa agcaagccct gtacgatttg gtagaggaac cccgccttcg
    20341 ataatctggg actgttgcag attgtttttg gtcatttttc gatgggttgt ttcaaaatat
    20401 gccaataatt ttttgtatcc ttccgtattt tgtatgagag acttaccgag gtgagccgca
    20461 gttgcttctt ttgtcaggtc atcttctgtc ggtcctaatc cgccacataa gagtatgagt
    20521 tcacttcttg tttcagctag agcaatcaac tcttctaaac gctgctgatt atctcctaca
    20581 actgtttgat aataaacttc gatacctaga tcagctagct gttctgacaa gaaagtggca
    20641 ttcgtattca cgacttgtcc tagtaaaagt tctgttccga cagctattat ttctgctttc
    20701 attacttccc gctcccttat atagtatacg ctgtattttt atattttttt atttaaaaag
    20761 agggcaagga gctgtgacaa aaatcttgtc acagctcctt gttccaaata aacagtgttc
    20821 tcctgccaaa acctcggtca taagtcacaa tatacataaa acatgaaaag ctgttttttg
    20881 aaattatccc ttgtgactca gagttagacg gcaggctcac aacctctcca ctaaacgata
    20941 cttacattga tcctttgaac acaccgctgt ttttgatgaa gtaatccaca cctgaataga
    21001 tagtaaagat cagacaagca taaagcatga tttgatctac tggaataccg atcaggctga
    21061 atgggatatt attgataaac agcaagataa tagcaaccat ttgtgtagcc gtcttgactt
    21121 ttcccggcca agctgcagcc atgacttctc catgttcgac aagtagtaaa cgcaagcctg
    21181 tgacggctaa ttcacgacag acaatgatcg ctactaccca accaggggcc tttccttggt
    21241 caaccaacat gataaaagca gtcataacta gcattttatc tgccaacggg tccgcaaact
    21301 tgccaaaatt agtgacaagg cctcgcgcac gggcaatttt tccatctaac cagtctgtga
    21361 tactagctaa agcaaaaata actgcaccta ctagctgtgt gacagccagt gtggtgtctc
    21421 ctacgttaaa ttgtccccaa tctaaaggta aacctacaac caaaatgaaa atcgggatca
    21481 tacaaattct aagtacagtt aatttatttg gtaaattcac actatcgact cctttcttcc
    21541 ctattctacg tgactatcag cgaagtttcc accgatatta tttacttttc caaatgaatt
    21601 tattcaaagg agtattttta ttgaaattga tctttttgaa ttaacgaaga aggaccgcga
    21661 cacagatttg tcacgatcct tcttttttat acctacaagt aaacagatgc gtaaactaat
    21721 ttatacgatc attctgcgta ttgaagagta aggttcacat tttttggact ctgattgttt
    21781 tcccctggat taactggtac ggattctcca ttcgctttga tcgttgcatt gcttgctgca
    21841 ccaatcgtga tggtcgcatt tgttgctgtt tccggtaaca cggtactctg tgtttcattt
    21901 gctgccagtg tcccttgata aacataggca ttgtctacta gcacacctaa ccatacacga
    21961 ttgacagcag taaattcaag ggttacaggc ttggtagcgt ctgtgatatt tactgcgatg
    22021 gcactgccag aatcttctcc tgtagctatt gccattttct tttcttcact tgattttgtt
    22081 gttgattcta ctgtagaaga ctctttggtc tgcgtgcttt gctctgagga agaggactcc
    22141 tcgactgatc cttctacttt aagcgaagaa gctgtgtctc cgattattgg atcagcttga
    22201 cgatcttgcc aagtcatata gcccacgaca acgacaatcg ccaaagcaac caatcctaat
    22261 aaaatgacag gaagacttgt ccaaaagcga cttggatgcg attcttcctg atgcattgct
    22321 tttctagaag tacttactgt ttcaggctgc ggacgttcag ggaccgatcc tgtcaatttg
    22381 cttttcccat caaaaacatc gactaaatgg tctccatctt ctcctacagc ttcagcgtat
    22441 tgccgaataa atgcccgcac gtaaaattta ccaggcaatt ggtcaaaatc atcattgtcg
    22501 attgcttcca aataacgttt ttgaattttt gtaatctgct gtaattcatc taaagatatt
    22561 tttttattca ggcgtgcttg ccgtaatttt tctccgatgg tttcaaaagc cactcgttca
    22621 tcttctccag tctgtttgat tctccgaagc atctgctgtt gcaacgaaag acgttatgtt
    22681 tgggtgctgt gacaaaagtc atgtcacagc tccttttttc cgaataaaca ttgttctcct
    22741 gccaactcct cggtcacaag tcacaatatc caataaatat aagaagctgt tttttgaact
    22801 tgttccttgt gactcggagt taaacggcag gctcacgacc tctttcttaa acggtgttca
    22861 atcagctgtt cctcggtatt agctcaaaaa ccggcaaaat ataaggagat atttttccgt
    22921 atgtttctct aatactcagg tcaaaacgct gatttcacaa cctcttcctt aaacggtgtt
    22981 caaaagcttg catctgcggt aataagtcca accaagttaa aaacattaag aagctgtttt
    23041 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct tggtacacgg
    23101 tgttccagaa gtagcttctt cggcaataag ccgaaatatc acaaaaattt gagaagcaat
    23161 tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctttgatta
    23221 cttcgtttga ttttatttta atataagttg attaaaagag agcatgattt gttttatttt
    23281 ctcactaatt tttccaacac aactaagaat accataaaag ctgattttgg aggaggttcc
    23341 tactacaagt ctaaaacgaa atttaagact tttcctcata aaatactggt ttattttggt
    23401 ctcatgtaaa actcgctgaa ggcctcttca cttataaatg cttccccagc tgccagtacg
    23461 tctttcattt ggatcgaatc gatgatttca ggaagatcaa ataaagttcg atcgccaaat
    23521 aaactttgcg taaattgatt ggcaatatat tcgatcgaat ttaatgattg gaaatattgt
    23581 ccaagcattt tcttcttcag caaatcgaga tttgtttctg acacttccgg atcatcagcg
    23641 aatccaagaa tgatttcttt gactttttct gctgctttct ctggttcgtc cgtatctccg
    23701 ctgaagtccg caaagtgaaa ttcacgatcc aagctgaatt caaaaccaaa gctgtcatcg
    23761 ataattcctt gattgtacat cgctagatag tttcgagaag tattgcctaa aatcatttgg
    23821 aacaacagat tgattgctgt tttatagcgt aacagttctg ttccttcttg cggcaatgtg
    23881 tctaatcctt taataccaag tacaaattta tctcgtgtaa tggctgcttc caatgcactt
    23941 tgtttgatga tttcttttgt gttttcaggg aaataacgta caatttcttg ctttggaggg
    24001 aaattttttg cttcttggtt ttcccgaata agtttcatca atttctcagg ctccatctta
    24061 ccaactacaa ataaaaccat attgcttggc tgataaaacg tccgatagca cgtatacaag
    24121 tcttgagctg tgattttgtc gatactttca accgtgcccg caatatcgat atgcaatggg
    24181 tgtgtaggat acaagttatt tagtatgcca aaaaacatcc gccagttagg gtcgtcttca
    24241 tacatttgga tttcctgacc gatgattcct ttttccttgt ttacagtttc ttctgtgaag
    24301 taaggtgctt gtacaaaatc gatcagagtc gtcagattct tttctacctg atccgtcgta
    24361 gaaaacagat agctggtttt cgtaaaactt gtgaaagcat tggcggaagc tccttgtttc
    24421 ccaaataatt gaaagacatc accatcttct ttttcaaaca acttatgttc taaaaaatgg
    24481 gcaattccat ctggaacttt caccttttct ttttcaccat agggaataaa ttcgttatcg
    24541 atcgaaccat aattcgtact gaacaaacca tatgtcttgt gatagtcatt tttaggcaac
    24601 aaatacacgg tcaaaccgtt tggcagtact tcatgataaa gtgtttcatt gatttgctca
    24661 tattctgttt tattcatttg catttcctcc tgctaaaaag aagattgcct gcaattcgat
    24721 ttgctcagct acttgttgta tctctttgat cgttacgctc tccatacgtt tcaaccattc
    24781 ttcatcagat aattttgttt ccggcagcca gctgtccaaa aaagaagctt cgattgccgc
    24841 ttgcggagag tctagagaaa gcagatattg gtttctcagc attgcttttg tctgagacag
    24901 ttccaactct gttatttcac catttcgcaa actttctaat tgctcgtgaa tcagatgaag
    24961 tacttgattt cggttctttt catcgatacc ggtttggaca ctcatgaatc ctcggaacgt
    25021 atccacgcta ctagaggcat aataagctag actttctttc tctctgacat tcatgaaaag
    25081 tttagagtga ggaaaaccgc caaataaacc gttaaagacc attagcgcaa aacgttctgg
    25141 ttcatcgtaa tacacatttg tctgataagc taggttcagc tttgcttgaa cgattggctc
    25201 acgtacttgt cgttccttca cgatattcac ttgaggttgg gtataaaaca gatctggata
    25261 aactgtttcc cgcgactcaa atggtaattg cccaactgct tcagctgctt tgtccggatc
    25321 aacatcgccg acaacaaaaa tgtcgatttg atcatttgcc atcatttctt gatagtagga
    25381 cgctagcgaa ctagcagtga tcttgtccaa atcttcgact acgcccaacc ctgggatctt
    25441 ttgttccggg ctgttttcaa aataaagttc ttgcaaggca taggaagcaa aagtttgttt
    25501 atcttccttc aaactttcca aatatagacg cagattgttc ttttccaagt caaacgtcaa
    25561 ctgatcaaac tgatgatttt taatatttgg ataaaataaa acctctttta aaaaatctac
    25621 cgcttgagaa aaaaggtttg gatcattgac atattcacca ttcacaaaac tgatccctgc
    25681 gtttagccaa tgtaaatttc ctttttttct aactgataat ccaaagcttg cgccataaag
    25741 ctctgcaagt tgcgcactta actttgtctg atccggataa ttcaaactat ttgtttccaa
    25801 catgctgctg agaagtgaac gtttcgtgat gacttcttgt tgcagacgcg cagtaaaacg
    25861 gataaaaatc cggatcgttt tgtattgttt tgttggtaag acatgaagat tcacgccttc
    25921 tgccaattga tacaccatat ttatatgctc cttttcacag ttgattgccc gcttactctt
    25981 ttaatgggtc aacctgcctt ttttacttat tcctctgctt gaaatttata agttcaggca
    26041 attcgccgtt ttttctaaat gatgttacac tttatagtat agcatagatg ttttttatca
    26101 aaagaaacag acggctaaaa gcgtatattg tttttttatt ttttattttt cgatatacta
    26161 aagacaaata aaagaaggga gggtcattca tgatcaaaga attcaaagag ttcatcatgc
    26221 gtggagatgt cttggatctt gctgtcggcg ttgttattgg tagtgcgttt acaagcatcg
    26281 taaaccaagt ggtgcaaggc ttgatcacac cactaatagg ttggtttgtc gcaatgatca
    26341 caggtacttc tgatttagaa ggagcacttt caattcttga ctggtcgccg acaaaaggcg
    26401 tcacatttgc gtttggtaac gttattagtg ctatcattac atttctgatc actggttttg
    26461 tcttattctt agttgtcaaa gcggcaaacc gtgcgaagaa tttacgctcc aaagaagagc
    26521 aagtggaagt ggaagaaact cctactgcag aagattatct tagtgacata cgcgatcttc
    26581 ttgccaaaca agtggcagaa gacaatacac atccagtaga gcaaacaaat ctttccgata
    26641 cttctaaata ataaagaatc taaaaaaaag aaagccgatt ttcagtgtcg gctttctttt
    26701 tttagattct taacttgcta cttgttcctt tttcatgtcg atatgtggaa tatcatcttc
    26761 caaatacaca tctgagattg ccttgaatcc aaacgactca taaaaagctt gtaggtattc
    26821 ttgtgcgccg atcacgattg gtttttctgg aaaatttttc tggatcatgt taatcgtttc
    26881 ttgaacaatc tttcttccta aaccatcttt acggttgtcc tgatgaacaa ggacacgtcc
    26941 aaaatggata ctctccgctt cttcatatac tcgcgtgtag gcaaggatct tcccatcagt
    27001 atcttgaaaa aacgtatgcc aagcttgtcc atcaatgtca tcaacttctt gataaggaca
    27061 ctgttgttcc acaacaaaaa ctgcgattcg ttctttgacg atcgcgtaaa actctgctgt
    27121 tgacaattct tcaaatttct ttacctgata ttccactaag caaacgcccc ctgctttttt
    27181 attcttagca taccgattcg cacacaaaaa agcaaacgaa ccttacgaat ctcaggctcg
    27241 tttgcttttt aaactgcttc agttaaaaat tcgatctcaa ctgtccgagt aagtacatct
    27301 gaatagctgt aagatactcg ttcaaaagaa ttttcttcag gatccaaatc aacaacgaat
    27361 actgaaggat aggtttctgt taaaacgccg cggcgttctg tttgacgctt tcttcctgtc
    27421 tgagcaacca acatgattgg gctgccgata cgaccttcta aatctttctt gattgaagct
    27481 aaagttgttg gcatacagtt cacctctact atcaactata ccacatattt ttaaaatttt
    27541 caagtttacc ataaaaaaaa aagaaatgca ataaaaataa ataagaagct cattaagatt
    27601 tttctaaatt attcctcatt ataaaatttc aagtgttttt ttattttgag ttttactctc
    27661 ccgtaagcgc tcattacttg cttgtgatcc attgctaaac attcagccat gtctacaaaa
    27721 tcaacgcctt gcatataata atgaaaaatt ttagcttcta tttttgaaaa ctggatttcg
    27781 caattttcga ttgcttcttt taataaaaga tgctgaatcg ctaaaggttc ttgcaatgtg
    27841 atctctgcta aaaagtctgg tccttctgtc tctatttttt ggtcgattga gacttcatct
    27901 ttttgatcac gacgcttcag cgcgttctgc ttcctcaaca gagaatagat ttgattgctt
    27961 ataatgcttt tataataact tccaaagcta acacctttgc ttttttcgta agttctcaat
    28021 gcctgatata aagcgatcct tgcttcttgt tcccaatcct cagaaacata atttcttaaa
    28081 taataggtgt ttttcaaacg tagtaaaagt ggaaaatatt tttgatacag ggcagcaaat
    28141 gcttcttcgt caccattacg tgcagcgcgc aataactcct cagacataaa ataattcctc
    28201 cataaattcg tttatggagg aatcttatca tcaatgattc atcgaactga ttagaacgat
    28261 atgttattta ttttttctca ttaaatcgtc caatttttgg gacaattttt ttaactgctc
    28321 ttcattccat ggagaattac gtcggaaatc aataaaatgc atatctttat tttcttgggc
    28381 tattgttttt tccgtttttt ttatcgtctt atataattca taagcagaag ttcgtaatgc
    28441 tccttgggaa aagatcatcc actgttctgc taaatcgctt gtcgccactg tcacttgtgt
    28501 caaacggtca ttcagctgac cagcgattct ctcgatataa ctgtcagccg tttcgtcttc
    28561 tttcgtaaaa acaacatcca actggtattt cttataattt tgttggatgc ccggaactag
    28621 ttgggcatcg aagacaacga tgacttccat tccttcatat ttcgcataat ttgataaacg
    28681 atgtaaaaga gcttctcttg catccgccat tttgtcctgc tttttaagct ggacaagttc
    28741 cggccacgaa ccaatcatgt tgtagccgtc tacaatcaac agctgttttt tcatggtcta
    28801 ctccccctga cgttgggaaa aagcctgata cataagcaaa ccagcagcaa cactggcatt
    28861 taagctctgg acgtgcccgg tcatcgggat cgtcagcaat tcatccattt cttttttcaa
    28921 tcctggactc attcctttgc cttcattacc aatgactaaa gcaattgatc ctttggcatt
    28981 ccatttttgg aagtttgtgc cggtcatatc tgtgccaaat acccaaaatc ctgtttcttt
    29041 gagctgttgc acagcttgta ccaaattcgt cacgcgtgca acagggacat gttcgactgc
    29101 cccagtggaa gtctttgtta cgataggtgt gattccaact gctcggtgtt ttggtatgat
    29161 cacaccatcg acgccacttg cgtctgctgt ccgtaaaatc gacccaaaat tgtgtggatc
    29221 ttcgatgcta tccaaaatca aaaagaaggg gtcttctttt ttctcttttg ttcgttcaat
    29281 cagttggtca agggataaat attcataagg tgtaatcgca agaacgactc cttgatgcac
    29341 gccgtgatcg ctcaaagttt ctaatttttg tttaggaacc catttgactg gcacagcttg
    29401 ttcacgtgcg atttctttca gttcttctac tttttctcct cgtgaatctt cttgaagaaa
    29461 gagtttattc cctcgccctt gttgtagcgc ttctactgcg gcatggtgcc caaagacgaa
    29521 attatcttct aatgcttctt cattttgatc agaaactgac tgatttcgtc cagtttgctt
    29581 tttatttgaa tatctatttt gttttttgtc ttcaaatcca cgtttcgatt gatgtttgtt
    29641 tgttctttct ttacccattt ttttcaccaa ctttctgaat acaccagcgg atcaattctt
    29701 ccatccgctc ggtttgtttt gtcaaatgca gatagcccat gagcgcttcg aaccctgttg
    29761 cgacccgata cgtcgtaaca tcagcatttt ttgcgctcgt atggctttta gcatttcttc
    29821 ctctgcgata ataaagttct tcttcttctg tcaaaagatg ttcttccagc atttgctgaa
    29881 tcaaaaaggc ttgtgcattc gcagaaacat aattcgttgc cgcacgatgc agcttattgg
    29941 gttttgtttc tccttgatca atcaggtggt cacgaacata gatttcgtaa atcgcatctc
    30001 caacataagc caaggctaaa ccgttcaatt gtgtgtaatc tctcatgctt ctcttctcca
    30061 tcgggttcct tgcggtgtat cttctaataa gatccctttt tctttcaaca aatcacgaat
    30121 ttcgtcgctt cggacaaaat cacgattgct tcttgcttga tttcgttctt cgatcaattg
    30181 ttcaatctct tcatctaata actcttctgc tgtaaataaa ataccgaaga tcgaaagcca
    30241 ttgcgagaat aaagcttctc cttgtgccaa gacagcggca gaaactttcg gctggtctag
    30301 ataagtgttc agccacttag caagctcata gaccactgtg atcccatttg ctgcattaaa
    30361 atcatcgtcc atttcttcga tgaatcgctg ttctaaattt tctaacaaag cgattttatc
    30421 cgcatcatct gccaaattct ctgaggcagt ttcttggcgg aatttcaaat tgtcaaacgt
    30481 attcttcagt cgttgtaaat tggtggctgc ttctttcatc gtcgtttcac tgtagcggat
    30541 cggacgacgg tattgtgtgg tcgccatgaa gaaacgcaag acttgtggat caacgttttt
    30601 gatcatttca tgtacagtga tgaaattccc tagagattta ctcatttttt catcgtcttc
    30661 gccaatcgtt acatagccat tgtgcatcca gtaattagcg aattttttcc ctgttttcgc
    30721 ttcactttgt gcgatttcat tttcatgatg aggaaattct aaatcttgcc cgccaccatg
    30781 gatatcgatc gtttctccta aatgttttgt tgccataacg gaacattcaa tatgccaacc
    30841 gggacgtcct ttgccccatg gtgaatccca agaaatctcg ccaggttttg cttgtttcca
    30901 taaagcgaaa tctaatgggt cttctttttg ctgctgttct tcccctgtac gctgacttgc
    30961 tccgacttcc agttcatcga tggattggtc acttaatttc ccataatttt caaatttacg
    31021 ggtacggtaa tacacatcac ctgaagattc ataagcatag cctttttcaa ccaacacttg
    31081 aataaatgct aaaatatctg gcatatgatc catgactctt ggatgcagtg tagcaggctc
    31141 gacattcaac gctttcgtat cttcttcaaa tgctcggatg aaacgatcag caacttctgg
    31201 tgctgtaata cctaattcgt ttgctgtacg gatgatttta tcgtctacat ccgtgaaatt
    31261 cgatacgaaa tcgactttat agcctcgata ttcaaaatag cgtcgaattg tatcgaaagc
    31321 aatggtgcta cgagcatttc cgatatggat ataattatac acagtcggtc cgcagacata
    31381 cataccgaca tgtccctttt gtatagggat gaattcttct ttttttctgg tcaatgtatt
    31441 gtagattttt atcattctga tctcctcact ttttctcctt tgattcgaac gacttttgct
    31501 ggtactccta ccgctgtagc gtcgtctgga acatctttca acacaacggc acctgcaccg
    31561 attttggcgt tttttccgat cgttaccggt cctaatatct gcgcattcgc agagagcatg
    31621 gctccttgtt taacagttgg gtgtctttta cccgtttctt ttcctgtgcc gcctaatgtt
    31681 acgccatgga ataaaatcac atcgtcctcg atttctgcgg tttcgccaat gacgattccc
    31741 attccatggt cgatgaacac gccagttcca atcgttgctc ctggatggat ctcaacacca
    31801 gttaggaaac gccagaattg agcattgatc ttcgccaata aaaagagccg gtgctgatat
    31861 aaaaaatgag agaaacgatg ccaaaacaag gcatgaaaac cagggtatgt caaaacgatc
    31921 tcagctgtcg aacgtgcagc cggatcgttt ctctttgctg catcaatcgc tcgggtaaac
    31981 caactcatga ctttccactc ctttcgtaag aattttatgt aggaaatcat cttcttataa
    32041 agaaaagaag cgccttttaa ataagtttcc ttatcaaaag acgctttccg cgtggttcca
    32101 cttttcttca taatcaatga ttatctctga cagctaacgc ctgttatacg ttcttggcta
    32161 ctttgtttcc tataaaacag tttttcctgt tttctgtgtt tcgccaagac cactcccaga
    32221 ggcatttcgg caaccattca ttgatacctt gcaccacccg gtatctctct tgtaatgatc
    32281 agctgcttac ttttttctgt tcatcgtgtt tagttcagta cttgatttaa atgtgctaat
    32341 gatttttcac gaccaagcaa ttcgatcgtt tcaggcaatt ctggaccatg catttgtcct
    32401 gatacagcta cacggattgg catgaaaaga ttttttcctt ttacgccagt ttctttttga
    32461 acagctttga tggcagcttt gacagttgga gcatctacta cttccatttg ttctagctgt
    32521 gctttgaatg cgtggagaac agtaggaact gtttcaccag caagtacttc ttttgctgct
    32581 tcattcaata caggatgttc attgaaaaat agcgtagaca gatcaacgat ttctgcagca
    32641 tagctcattt gaggttgata caggctaacg atcttcttca cccattcgat tgtcttttca
    32701 tctgggtttt ctgctacacg tccatcagcg attagataag gcagacacat gtcagtaaat
    32761 gcatctagat ccattgcttt gatgtaatgg ttgtttaccc attgcagttt tttcgcatcg
    32821 aaagctgcgg gtgatttact taggcgtttt ggatcgaaca ttttgatcaa ttcttggtgt
    32881 tcgaagattt cgtcttcgcc cacaggtgac cagcccaata atgcaataaa gttgaacatt
    32941 gcatctggta gatagcctaa ttcgcgatat tgttcgataa attgcaagat tgattcgtca
    33001 cgtttgctta gttttttacc tgtttcactg ttgatgatca atgtcatatg tccgaaggtt
    33061 ggtggtgtcc agccaaatgc ttcatagatc atcagttgtt ttggtgtatt ggcaatatgg
    33121 tcatctccac gtaaaacgtg agtgattttc atcaaatgat catcgaccgc aacagcaaaa
    33181 ttataagttg gcataccatc gcgtttttgt atgacaaagt cgccaccgat attatcggat
    33241 tcgaacgaaa tagcgccttt caccatatct gtaaatgcgt attctgtatt gcgaggcaca
    33301 cggaaacgta caacagattc tagaccttgt gcttcttttt ctgcttgttc ttcaggtgtc
    33361 aagttcgcac atgttcctgc gtaatgaggc atttctcctc ttgcgcgttg tgcttcccgt
    33421 tctgcttcta attcttcttc tgtgcaatag catttgtatg ctcgattgct agcaagcagc
    33481 tgatcaatca gcggttgata gatttcttta cgttcagatt gacggtaagg gccgtattct
    33541 ccaggatttt caggagattc atcccaattc attcccaacc aagcaaggtt ttccaactgg
    33601 cttttttcgc catcttcgat attacgtttt tggtcagtat cctcaatacg aataataaag
    33661 tctccatcat tgtggcgggc aaacaaataa ttgaataatg cagttcttgc atttccaata
    33721 tgcaggtgcc cagttggact tggtgcatag cgtacgcgta ctttcgtcat tttcttcctc
    33781 ttctttcaaa ctagactttg actaacagca aaaattccgt cagttacggc ttctcaaata
    33841 tcatttattt aaagccactc agcacaaatt ttaccttttc taaggtaaat agtaaagcca
    33901 actggttgaa tttccttacc agttggctga atttcttttt tattttgatt gtttagtctt
    33961 tttctctgtc tcttttttat tgtcgattcc tcgtcctgca tgtgcaggtt tagcaaagat
    34021 catgcgtcca gcagctgttt gaagggcact tgttacaacg acttcgatac gttcattcat
    34081 gtaatgctgt ccatcttcta cgacaaccat cgtgccgtca tcaaggtagg ctactccttg
    34141 ttggcgttct gtcccggctt ttactactag aacattcatc gtttcaccag ggatgacgac
    34201 tggttttacg gcatttgcca acgcattgat attaagaaca ggtacatttt ggaattcaga
    34261 gactttattc aagttatagt cattggttac aatgacacca tctaaaagct tagccaattt
    34321 gatcaatttg ctgtctactt cactgatatc ttcaaagtct ccatcgtaca tttcgacaga
    34381 tataccctct tctttttgca aggcatttag gatatctaat ccgcgacgac cacgcacacg
    34441 tttcaaacta tcccctgagt ccgcgatgta ttgtagttcg taaagaacaa aattagggat
    34501 catcaaggtt ccttctaaga atccagtctt tgtaatatca taaatccgac cgtcaatgat
    34561 cacgcttgta tccaagattt tatatttatg gaaattttct cctgattttc gttctaacag
    34621 ttgactctca acttgactag ctgtttcttg ctcgattttt ttgcttcgtg aaccaaaaac
    34681 tttcttccat tcttcgattc gtgtcgttcc cattctcaat cccagatagc ctaagatgat
    34741 catcagtaaa atcggcaata cactattgac gaatggaatt tccatattgt aaagaggggt
    34801 cgagatcaca acacctaaag tcaatccgat gatcgcaccg atcgcaccga agagaagata
    34861 agtcaagctg acctcactta gtttttgttc tacttgtttg ataatagctg agatatgttt
    34921 ggccaacagc aaagataata aaaagaaaat aagtgcgcct aacaggctgt tggtaaatgt
    34981 attattcagc catccgtttg actgttgacc gattgcctgc caagctgagg gtaaaaatga
    35041 aatacccaag cttgcgccga caatgatcat cagcaaagta atgacacgtt tttgcatcgt
    35101 ttttcctccg tttcgacaat catttattag ttagcggaac acacgcttca acgtttcagc
    35161 caaagttgct actccaacta tctcgattcc ttttggcgct tcccagttac ctaagttgtt
    35221 tttaggtagg tatacttttg tgaagccgag tttttggact tctttgactc gttgttcaat
    35281 atgactgaca cgtctgattt ctccagtcag tccaatttca ccgatgaaac attccgttgg
    35341 ctgtgttcct ttttctttat agcttgaagc aatactgaca gcgatagcta aatcaatcgc
    35401 tggttcattt aattttaccc cacctgcagc ttttaagtaa gcatcttgat tctgaagaag
    35461 caacccagct cttttttcca gcactgccat gatcagagat acccgattga aatcaagacc
    35521 tgttgttgtt cgtttggcat ttccgaacat agtaggtgtg actaatgctt ggatctctac
    35581 caaaattgga cgtgtccctt ccattgccac aacgatagca gagccagttg caccgtctag
    35641 gcgttcttct aagaaaatct gtgaaggatt agcgacttct tccaatccat gctcatgcat
    35701 ttcaaaaatc ccaatctcat tcgttgagcc aaatcggttt tttactgctc gcaaaatccg
    35761 aaaactatga tgttgttcac cttcaaaata taacaccgta tccaccatat gttctaacat
    35821 tcttgggccg gcgatcgagc cttctttggt aacatgaccg acgataaaaa tggctatccc
    35881 atttgtttta gcgattttga gtagttctgc agtggtttct cttacttggc tgacacttcc
    35941 tgccacactt gtgatgtctg gctgcgtcat cgtttggatg gaatcaatga taacataatc
    36001 aggggagata tgttcgatgg cacgactgat ttcgttcata tctgtttcag cgtatagata
    36061 aaattctgtg ttgatacttc cgaggcgttc cgcgcgtaat tttatctgct ctgcgctttc
    36121 ttcgccggat acatataaga cttttccgcc tatggctgct aattgctgag aaacttgtaa
    36181 cagcaaagtg gatttcccga tacctggatc gccaccaatc aagaccatag accctggcac
    36241 cacacctccg cctaacacac ggttcagttc ttctaatttt gttttgatcc gaggttcttt
    36301 tttagggacg acgtctgcga tttttgttgg ttttgctttt tctcctgtca aacttgtccg
    36361 agttctgcgg tccgttgtat cttgttcgat ttcttcgacc atcgtattcc attttccgca
    36421 atttgggcag cgtcccaaga acttaggcga cacatacccg caattttggc aaacaaattg
    36481 tacttttgat ttttttgcca ttgtaccgcc tccttttatc ctaatcatga gacattaaat
    36541 caagcttaag tatctttaac gttttattta ctggaagaac caaatccgcc ttgacgttga
    36601 gcagtcgttt gatcttgatc tgcttttaaa aacggcaaaa agatcccttg gccgatacgc
    36661 tcgccttttt tgatcactac atccttgaaa ccaaagttgg tgaattggaa catgatatgg
    36721 ccttcatttg cctcattatt gtaataatca ctgtcaatca cacctactcc gtttgtcaac
    36781 actaaaaacc gcttcaacgg attgcttgaa cggttagcaa gctgcaaaaa ttcatcttct
    36841 cccatgtaag ctttgattcc agtaggcacg agggttggtt tcaattgttt ttcattttct
    36901 gatacatctt ttttcaatcc atctgcgact gtttccaacc cctttttcca gcctgctttc
    36961 cagatacttg gaatcacgac ctcttctgct gcttcaaaat catagccagc agcatgatgt
    37021 gtagcgcgct gcggtagatt gatattttga tctttatatt tagaaataac ttcaaatcct
    37081 ctttttctca ccggttttcc tccctaaata aactactcct attctaacat atccgaggct
    37141 gtaaaagact ttctttacaa attcttcaag aaattctgct atcttaaagt aaaccattaa
    37201 ttcgttcttt ttccaaacga ctgcaagttg tacaaaaaaa ctatttttta catgacttta
    37261 ctcgtcaaaa caagtagaat agaacgaaat taatgagtgg atatttgatt gaggtgtcac
    37321 atgcgtaaag aaattaaaaa tgcaaaacga attattgtca aagtaggaac aagtacattg
    37381 atttatccca atggaaatat caatcttgcg gcaatcgatc agttagcttt tgtcctttct
    37441 gatcttagaa atcggggaaa ggaagtgatc ttagtctcat caggagctgt aggcgttggt
    37501 atgcataaat tacatttgtc agaacgtccg actttgattc ctgaacagca agctgcggcg
    37561 gctgttggtc aagccgaact gatgaatatc tataatcaaa gattcagtgt atataatcaa
    37621 cagacggcac agatcctcgt gacaagagac gtggtagatt atcctgaaag tcgtaaaaat
    37681 gtgaggaata cattggaaca gcttttgatt atggacacga tccctatcgt gaacgaaaac
    37741 gatactgtag cagtggatga attagatcat ctgacaaaat ttggcgataa tgatcagctg
    37801 tcagccatca tggcaaaact tgtcgcggca gaccttttga tcgtcctttc tgatatcgac
    37861 gggttttatt cagataatcc gactacaaat cccgaggctc agatgtatcg ctatatcgat
    37921 aaaatcgatg aaaagattct ggcacaagca ggtggtgctg gtagcacatt tggaacaggc
    37981 ggtatgcaga gtaaattaaa agccgcttct aggatatttg aagcaaacag cgcaatgatt
    38041 ttagcaaatg gaaaaaatcc ggcaattatt tttgatattc ttgcaggaaa agaagtaggt
    38101 actttattta aggaggactt gaaatgactg acttgatgca attaggacaa caggcaaaag
    38161 atagcgcgca acaactagca cttatgccta caaaccgcaa aaatgagcta cttgttcaaa
    38221 tggcacaaac catcaaaaag aatcaacaag cgatcattga agcaaatcat aaagacttag
    38281 aaaaagcagt cgaaaacaat atcagtgaaa cgatgcaaga ccgcttgcag ctgacacctg
    38341 agcgaatcaa tgccatggct acagagatcg aaaaaattgc ttcgttagac gatcctattg
    38401 gaaaagtaga tgagatgtgg acgaacaccg acggattgag aatcggcaaa aagcgcgtgc
    38461 cactaggcgt gaccggcatc atttacgaat ctcgtccaaa tgtcacgaca gatgcagcta
    38521 gtctagcatt caaatcaggg aatgccgtta tccttcgcgg tggcaaagaa gcattcttct
    38581 cgaatcaatt attagtccaa ttattgcagc aagtactggt cagtgctggc gaatctcctt
    38641 atgccatcca gtttgtcgat gatacttctc atgaaactgc aggacagttg atgcgattga
    38701 cagaatactt agatgtgctg attcctcgag gcggagcaaa attaatccaa cgagtcaaag
    38761 aacaggcaac ggtacctatc attgaaacag gtacaggaaa taatcacgta tatatcgata
    38821 aagaagcaca gttatctatg gcagtgaaca tcatcgtcaa tgcaaaagct tcccgtccat
    38881 ctgtctgtaa cgcggcagaa acattgctga tccattctga gatcgcacct tttttcttgc
    38941 cagctattga aaaagaactg gtagaacacg gggtctcttt acgtgcggat gctcgtgcgt
    39001 tagaatatct agagacggct gctttagcag aagacacaga ttgggatact gaatatctag
    39061 attatatcct tgctgtcaaa gtggtcgatt ctttggatga agcaattgca catatcaatc
    39121 ggcataatac taaacattca gaaacgatcg tgacagatag ttatgcggct agtcaacgtt
    39181 tcttaaatga agtggacgcg gcggctgtct atgtcaatgc ctccactcgt tttacagacg
    39241 gatcggtatt tggttttggt gcagagattg gtatctctac tcaaaagttg catgcccgtg
    39301 gtccaatggg gttaaatgaa ttaacttcca caaaatatat catttatggc gatggacaaa
    39361 tccgcgaata atgtttcgtg tgaaacatta ttcccgcctt ttgccttttt tctgtaaagg
    39421 ttctatccaa ctagaaaggt gtcaatatgt ttgaaatttt aatgattttt tttatttacc
    39481 ttatttctct gaatatcgct gcttttctgg gagtcggtat tttatccctt ttctttcaat
    39541 tcaaaaaacg aagcataggg agtcaacggg aaaaatggtc gcagtatttt gacaaaatcg
    39601 ggcaaaaagg gctggttaca cgcttgcaca ttagttacat ggttgcatta tgcttattag
    39661 cgacaatcaa ttactattct tttttcgatc attcaatcgc ttatacgatt acgctactga
    39721 ttgctgggat ttttcactta tcttataaat atcagctgaa taaaaaccac ttgaatcgga
    39781 ctttccgcta aaaaatatcc gtacgataag tagagtgcct tgaagatcgg caaaaaactg
    39841 ccggactttt tagaggctgt gacaaagatt ttgtcacagc ctctttttcc atataaacgg
    39901 cgttcgccta ccagctgcct ggtaaatctg tttcctcttc gttaagaagc gaaaatccgt
    39961 caaatgtttc gccatcataa taacgaagca gctcatccat ggacaagttc atcgtttttt
    40021 ctttttcttc ttccgctgat tcagccagta gctgttcccg atacacctga tacataccag
    40081 ctattttttg ctgcatcgct tttctagttt caccttccgc attgattatt ggcaattctt
    40141 tgatatagcc acgataaatc aaccgatcat ctgaaaattc aatgggtaat tcaacgagtg
    40201 tcaacccgac ttcctgaaaa tattcttcca gcatctatta tccccccatt ctttttctta
    40261 aatgaatttt agcttaccta ctgaaaattt tccagtttca ttattttgag aaaaaaaggg
    40321 aatgtgacaa aaatcgtgtc acatcccctt tttccgaata aatggtgttc ttctgccaac
    40381 tcctcaatca taagtcacaa tattcaacaa acatgagaaa ctgttttttg aaattgttcc
    40441 ttgtgattca gagttaaacg acagtctcac aacctcttgg taaacggcgt tcaaaagctt
    40501 gcatctgcgg taataagccc aaccaaacga aaaatatgag aagctatttt tgtttggctg
    40561 ttcttatgac ttgatgcagg acagcttttt cacaacctct gatttcttat tcttcttcat
    40621 ttgtagcaaa ataattacgg tgataaatga tacaacatac actgataaga acaatggcac
    40681 ctgcaaaata aaacgcatag ctttcaccaa tatgttcacc aatcacacct gcaataaatg
    40741 gtgctaaagc tccaccgaaa aagcggacaa aactatagct ggacgaagca acgtttcgtt
    40801 gcagacctgg tatttccata gcaatcgtcg tcaacagtgt attgataatt ccttggaaaa
    40861 atcctgctaa cacaatgctg atcggtacaa ggactggcat agaagttcca gctcctaata
    40921 acagcaaaca aataatgaat aagacaaatg ctgctaaaat tgtccgataa gtcgtaaact
    40981 tccgctcaag agccggtgca acgaaaatcg aagcaatagc cagaagcaca ccccagccaa
    41041 aaaatacaaa accgacttct aattcagaat agccaatcaa taaaaatggc gcatacgcaa
    41101 gtaaagtaaa gaatccgaaa ttatataaca atgcgattag tccaactgaa cgaagtttat
    41161 gattgcttaa cgctttgaca ccttcccaaa ggcctacttt tctctttggt ttctcagttt
    41221 caggtaaaag taccgctagg gctataaaac cgcaaaacat caaaaatgct accccaaaaa
    41281 atggataacg ccatgaacca ctgcccaaga ccccaccgac tagagggcca acagccattc
    41341 cgcagccaag tgctgcttca tacatcatga ttgctttttc tgtgttacca actaaaatac
    41401 tgacgatcgt tgctaaagca gtagagacaa ataaagcatt cccgacaccc cagccggcac
    41461 gtaacccaat cagcattccg atattcccag ataatccgcc aagaccagcg aatacaacga
    41521 tgataaacaa tcctgtcatc aatgtttttt caaaccgatc cgactagata agaaacctgt
    41581 aaatagcatc accacaccag tgactaacat gtaactagta aataacaggg tcgtttcagc
    41641 tggcgtagcg tttaactgtg cagcaatcgt ttttaagatt gggtctacta gacccactcc
    41701 cataaaagcg atcatacagg tagctgctac aactagcgct gaacttttcc cctttgtttc
    41761 ttcatttgtt tgttcttgta tatctatttg attctccaat atttccatcc ctttctctct
    41821 attagcatca tacatgattt attttacatg taaatatgca catgtaaaac gtggaaactt
    41881 tactgtgata taataaagaa aataagacga gaggtaggat ttttatgaat actttagcct
    41941 atatattatt atgcgtgctt ttatccaaac cacgttctgg gtatgaattg aagcagctga
    42001 tcacaatttt ttgggaagcc catcacagtc agatctatac aacgcttgcc aagttagacc
    42061 agcagggtta tgtgaccgtt ttggacaaag acgagcactc tcaaaaaaag atctaccact
    42121 tgactgatga aggacgtgct cttgtagagg aatggatcaa agaggaaact cccgctccta
    42181 cgcaaaaaga tgaatttcta gcaaaaatct atgctttttc gacgctcgat aaaacaacag
    42241 ctactggact gctattcact agagaacaac agctgaacaa aatcatgcaa aaaaatcaaa
    42301 aaaaattgaa tgacctctcg ctagacaaga aacaagaatt tggacgttat gttgtgatcc
    42361 agcgcagaat tatgctttgt cagcaggaac tccaatggtg tcagcaagta agagaacaaa
    42421 tgcagcagtt ttttgagtaa gggataaaca gaacctttct agaaatatct attgaagagc
    42481 aaattatctt caataaaaga gcaatacagt tggaaaagaa aaagcgatcc gaacgacagg
    42541 ccaaaaccta tcgttcggat cactattttt ctagaactgc attcaagaga ctatgacaaa
    42601 aagcatgcca aggccttttt tcaaataaca gtgttccatc attcattact ttgaattgct
    42661 tttagcacac ttcttgaaag cgggccaacg atgatcaact gcaacggtaa agcggcaatc
    42721 acattcattt tccaagcatt catataagca gagaataatt gatcaggtat tccttgttcc
    42781 atgatcacac cgaataaaga catacatgtc accattccta aaaccatcaa gcatgaaata
    42841 gttaagatca tttggacctt gctttctgga tttactggta gtttaaaggc aatttttttc
    42901 gccagcacac cgatgatgaa gacatccaaa atgaaagcca ccacgaatcc aggcactaga
    42961 ccaatcaaca aacttgataa atgaagatct tgatgcagcc ataaattata cgcgctcatc
    43021 cccaagacca tcaaaaaaca catcattgtt gtaaaaatta ttccttcttt tttatttgta
    43081 ggcaatctgt accactcctt taaatttgtc acgaaaatca tcgtagcaca tttaaaaatt
    43141 tctcgtaagt acttttttta ttttctgccc ttttatttca taaacttcat cagccgtacg
    43201 ctcgacaaag taagaatcat gagaagtaaa caaaatcgtt cccggatata tttgcattag
    43261 cttctctaaa gcttcgatcg ttgccatatc aataaaatta gtcggttcat ctaacagcaa
    43321 cacattactt ggcttagtaa aaagcaaagc aatcgtcaga cgggtcgctt ctcccccact
    43381 taatgtacat aacggtttcg tcaaagtttc ctgagcaaac cctaagtgat tcagcaaact
    43441 acggacaagc gattctgaaa actctgtttg tctcatgaca aaacgaatga tggattcttc
    43501 agatgtcatt tgataaccct tttgctgata tacttgaaag cttactttcg gagagagaag
    43561 gattccttct ccttgtttgc ggatatgttc taataaggtt gtcttacctg aaccattttc
    43621 accgacaatc gcgatttttt tacctaaaga aaactgaaaa tcaccattta ccagtaatgt
    43681 tctcccactt ctttccaatt ggacattttg tcccatgatg ggatagcggc tgtggagttc
    43741 aagagatttt ggtactggaa aacggatttg tttcatctgc tgcggcttgg ttgtttctcc
    43801 tattttttgg agtcttctct ctaatgtttt cgcattcttt tggatggctt tttgtacact
    43861 gtctttttgt ttagaggaag acaaccgatc cggtctgatt tgttgctttt tctttttact
    43921 ggacactttt tccaactttt ccgcttgttt tttcttttct tggatcgatt tttccaatcg
    43981 ttttttctct ttcatgatcg actctgcttc tcgtagctga gtctttttct ccaattcctt
    44041 ttgagtgaga taggcactat aattccccga aaactctcgg atttctccgt cttttacttc
    44101 ccagattttc gatgctagct catctagaaa atagcgatca tgactaacaa aaaccagcgt
    44161 accataataa taacgaagct cttcaatcag tcgatcaata ctttttctat ctagatgggt
    44221 tgttggctcg tctagaagca tcccttgttc ataagaagaa agaagacgta tcaactcgat
    44281 ctttcgttct tcccctccgc tccatttccg ctctgaagtt tcttccagtc ttaactggaa
    44341 atgactggct aattccaaat ttaggtcctt tgcttcagcg agataggtta attgaggcag
    44401 gtagttgaag gtgatctctg tttggatttt cccatgatcg ggaaaaagtt caccggctat
    44461 tagtttgagc aaagtcgatt taccgacacc attttctcct atgatcccta tacgatcttg
    44521 ctgatagaca cgaagagaat caatagatag ttctagctgg ttgccaaagc tgacttgtag
    44581 atttgttata tttactgcta aattttccat atgttttaca ctcctatttc atgtaaaaca
    44641 acaattatcg atactaaaaa agagcagaaa aatctgtttg caaaaaaact gcatcacatc
    44701 ttttcctact ctgaacgaaa taactatgac taaatcacca aatctgtcat agctttcacc
    44761 tattctactg tcgttcgaaa aaatggacat actccatcca tgaaattgtt gtttatacat
    44821 gtcttttgaa tttatttagt tgttattcaa aagttcgaaa cgtaatttca tcgatgcagt
    44881 catttttccg acctcctttt ttattaggtt accacacacg attcaaaaaa agcaatagct
    44941 actgaatagt aactgaaaac cttttattcg aacgtagtga tcttttctgg tgctaaacga
    45001 acagactcgt aaccttcttc taccgctttt cctattgata aaataataac tggaacataa
    45061 cggtctttat ccaaaccaaa tgcctctgcc aactgatctg cttcgaatcc accaattgga
    45121 tttgtttcat agccatgatc acgcgcaact aacatgaatt gcatagccgc taagctagaa
    45181 tcgactttga ctacatcgtt catttcttct cttgaaaaac tcttgtaata aggaatgatc
    45241 gcagctaatt gttgatctct gacttctttt ggcatcttcc ctgattcgta agcttggtta
    45301 tagatttctt cgccatattc gtaacattgc atatcgccaa aaatcatgac cattgcagaa
    45361 gaagtatcat tttgtctcgt attgaaacgg atcaaaggac gcaagatttc ttttgcttcc
    45421 tcgctttcag cgaccacaaa gcgccatggt tgcatattga cagaagaagg tgcagtcgtc
    45481 gcttctttga tcatttccag catttcttcg tgtgggattt tgtatgtttc atcatatacg
    45541 cgaacggatc ttctaccagt cataattgtt gaaaaatcat ttttttgttc cattattatt
    45601 aacctctttc gtttctgttg ttatattgca aagttgggta ttcaatttat ctaaaagtgt
    45661 tagaaattgt ttcatttcta catcgctgaa agccggggat agcacggaac ctgtatcttt
    45721 atggtccatt tcacaatgct cgattttctt ctgggctttt tctgttagcg ctacatacac
    45781 ttcccggttg ttctgaggat ttctctgacg cgaaacatag ccatttgctt ccaatacctt
    45841 cagatgacga gtaactgctc cttgatcaat ctgcaacttt tcttgcaaac tgctttgtag
    45901 caatggattt tcttctttca gtctcatcat gatctcgtat ctagtaagac ttataccgat
    45961 attttcttca aagatctgga cgattttttg atcggctaat ttgatttgat ataaaaggtg
    46021 actaatctct tctaaagaca taatttcctc ctttctaata attgactcgt caacgattga
    46081 cttgtcaata atagaataaa aaaagaaaaa agtcaaagaa tcagctgtgt aataaaaaaa
    46141 acgctctcaa tagaaaagta tagagaaaag aaattttttg tagaatgaac ggaaaaaatg
    46201 ataaagaaag cacaacgcta aaaccaagat tattgattct tatcaaacta tagaagatag
    46261 ctcttctgca gtagaaaatt ttacaccgcc aaaaatttcc gaaatcgcct tttgcaagaa
    46321 tcccgtcgaa tattagaaat tggatcagta tgcttaaaca gtaataaaaa agttatgaca
    46381 agatgttgtc acaacctttt ttgagtaaac ggtgttcaaa aacttgcatc tgcggtaata
    46441 agttcaacca aacaaaaaac atgaaaatct gtttttgttt ggctgttctt actacttgat
    46501 gcagggcagc tttttcacta cctcttttta ataaccataa aatcctattc cttcatatct
    46561 ccagcccatc ggtgttagcc aatctctttc cttagcactc aaggtatagt gatgggtacc
    46621 agttttttca tttggattaa atagtcgata aattggcttg gaaccaccag aataaaaact
    46681 tagaccttca taacgccaac cgatttttgt taaagagttg atctcagatt gtgccattgt
    46741 gtaatgatgg tctccactgt aaggattgta taaacggtag acaggttgtc cgctgtttgg
    46801 tgcttgccaa gcaatccctt catattccca gcctacagtt ggcagataat ttttttctcc
    46861 ggcattcaat gtatataaat gttctcctgt atgacggtta tacagacgat acatcggaga
    46921 agttgaagtt ggtgctgtat catactgtgt cagattatag gtttcgatta cattgttcaa
    46981 tgtagaacca taattaggcg cagtggcata acgacctgtt agccaagccg tagcatcttt
    47041 gtaagagttc gtattgcttt tccatgcacc ggaatagtag taaacgcctg gctgaaaaga
    47101 agtcgtcttc aataccgtta cgttatcttg caatgattct ttgtacgaag gatattttct
    47161 aaaagcggca ttcaccgtaa tccattgccc attcacatat tccgaagtag gcatcgtaac
    47221 agattggcca ttatagcttc ctttaatccc aaatagattg taattagggg cagaagccaa
    47281 agtactgttc ccccagccac tttcaacgat ggcttgagca atcatgactg atgcatataa
    47341 gtcattggca cttgccaaac tttgtgcagt tgaggcaata ctatcaatga acgcttgttg
    47401 agaattagca gatgagcgag cataaaaagc atagccagta tagttttcga attcagacaa
    47461 atctgcttga tgggtatgtg tcaatgtttg cccatctgtc aattggttcg tgatttcttc
    47521 tgcattctct ggattgttct gagcttctgc tgatgtactg tcttcggttt gtgtttgttc
    47581 tgttgtttca gttgttggtt cttcggttga aattgtattt tctgagacag tagctgactg
    47641 caaagtactc tctgtatcgt tttcaattcc tgtttctgaa gaactcgatg tctgagttgc
    47701 gacagtttct gtcgattctt cagctagcac tgttgtgttg gcaactgcta gatttcctaa
    47761 aagaataacg ctaaataata aattctttgc tttcatcttt tttctccttt gaattatgaa
    47821 acttttccta aataacagtg taactaaaaa agtaaaagca agtcaatgtc catatttaaa
    47881 taacatttgt ttctttttga taaatttgct ttttctacat aaaaagacgt aaatgaagaa
    47941 tattcttctc cattcacgcc ttaaattgat ggtcgtttga ataactattt aacaagtaat
    48001 tctctttgga tattatccgt tatggattat acttcctgtg tcgtcggacg gataatcatg
    48061 ttactgacag acatccggtc tggcgtttct atcgcaaatg ctacagcaga agctatatct
    48121 tcggaggtca atccccattc tttttgcgct tcatgaagtt caagagcagc ctttttgtcg
    48181 ctgatggttt gatataattc agtttgaaca gctcctggag agatgatcgt agatttgatg
    48241 ttattttgcc gttgctcttg acgtaatcct tccatgattg cacggacagc aaattttgtt
    48301 ccgcaataaa cggcggaatc aggataaaca acatgtcccg ccacagaatc agttgaaatg
    48361 atatgcccag atttttgttt ttccatgatt ggaagtacgg cggaaattcc atttaacaca
    48421 cccatgatgt tgatatcaag catattttgc cattcatcac ggtgaccttc aactaatgga
    48481 gcggttggca tgattcctgc attattgtac aatacatcga ttcgaccgaa cttttccatc
    48541 gctaaatcga taactgcttg gacttgtgca aaatctctta catctgctgt ttgaatatat
    48601 agctcagctt ctggtaaaga ttcttttatt gcttttaggc gatcttctcg gcgtgcagct
    48661 ataactagtt tagccccttt ttctgctaat agcttcgttg ttgcttcacc gattccgctt
    48721 gaagcgccca tgatgacaat cactttttct gataaatcat tcattctatt ctcctcctgt
    48781 tttgaaaaat ctcttgctta tactcactat ctcttatttc atcttactgt tcaaataatc
    48841 cgttcgacag gtttgacgat tttggcaggg attcctgcaa cgatggtatt gtctgggaca
    48901 tctttcgtaa cagttgcatt cgctgcaaca atggcattct cgccaatcgt tacgcctggc
    48961 agaatagttg ctcctgctcc gatccaagca tttttcttga tgtggattgg ctttactgac
    49021 aagcctcttc gttcttttgg atcggttaga tggttcaccg tgatgaggtt gacacgagga
    49081 ccaatcaata ctgaatcttc taaacagatg ccacctaagt caacgaacat cacttgacga
    49141 ttgataaaga catttttccc tatactaata tgtttgccga aatctgtata aaaaggcagc
    49201 agaacagtca ccgtatcatc tactttgtca ctaatgatat tttctagccg tttgcggata
    49261 tctgctggtt catggtaccc agtattcagc gctgctaaag gctcttcgtt ttcagcttgg
    49321 atctgatgga tcacttcaaa gagcggatcc gttactcgaa tctctttatt gacgatttgt
    49381 ttttcgatga ggcttgtcat tttgctccct ccttttatcc ttactttata acggacggct
    49441 tatcatgtct aatacttata aaacatactt aactattcct tttaactata cttagtggta
    49501 tgctttttta aaaacaggag ggaaaaaatg gatattcgta tactgacgta ttttttagca
    49561 gtagctagag aaaaaaatat cagccgagca gcaaaatctc tgcatatcac gcaacctact
    49621 ctctcaaaac aactgaaaga tttagaagaa gaacttggtg tgacactttt cactcggggc
    49681 tcccgagaga tacagttgac ggattctggt cgatatcttt attcaaaagg aaaagaaatc
    49741 ttgtcgttgg tagaaaaaac ggcgaacaat ttaacaaatg acgcaatcat ctctggagaa
    49801 atctacattg gcggaggcga aactaaagca atctctttca tttctgatag ccttcattcg
    49861 ttgatcaagg cgcatcctga tatccagttt catttatata gcgggaatgc agatgatatc
    49921 atagacaaac tggatagcgg attacttgat tttggactcg taatcgaacc gacaaacaaa
    49981 caaaaatacc agtcatttcg actgccagcc caagatcgtt ggggactttt gatacatcga
    50041 aatcatcctt tagcaaagca aaccgtcatc catccgcagg aactgaaaac tgttcctttg
    50101 atcatttccc ggcaaacgtc agtggacagt caactagctg aatggctagg tttcagcata
    50161 gatcagttat cgatcgtcgg aacatataac ttattgtaca atgcttcttt gatggtcgat
    50221 aacgggactt ttggtgcatt agctctagat gggatcatca atacttatgg gacggaaaaa
    50281 atattcatcc cactcgatcc gccattacaa gcttcactga atctcatttg gaaaaaagac
    50341 cagcctcttt ctcctgctgc tcgtaaattt ttagatgtcc taacggagaa atacagttaa
    50401 gtagagtttt tttccttcgc tttcagcttt ttaacaacga ataagataag caaaagatcc
    50461 aacgattaaa taacataagt ttcttaattt atttcttcct tttatttctg ataattccag
    50521 taaattacta taattataaa aaaagaattg acaaaacata actgtctata taaaattgat
    50581 tacgttaaca ataattcgtt tcatgtgact agatcatact aggcatgaaa aatctctgag
    50641 gaacatggtt tccctaggag gtttttcgtg tctatttttg tttggccgca atcaactggt
    50701 ctagcaaacg tgaaaaccaa atcttcaaaa agggtgcgcg catgaaaatc aaaaagatct
    50761 ttaatcaaaa tgcagtattg gtagatgacg gtggacagga aaaagtagct attggaaaag
    50821 ggattggatt tgacagaaaa agaaatgatt tgatttttga tcgtgatgtc gaacggatat
    50881 ttgtcatgga accagaaggt caaatcaagt tgcaaaattt acttaatcag attgatgaac
    50941 gctttttatt tgcagcagaa acgatcattg atcatgcgga aactgttttg atggaaaagt
    51001 tgaatgaaca tgtattgatc gctttgaccg accacattgc tttttctgcg gagaacatta
    51061 ataacggtat cgtcatccgc aacaaacttt taagagaaat cgaagtgctt tacagtgatg
    51121 aattcagtat tgctcaatgg gcagtagagt atctgacaaa agagcttggg attccatata
    51181 cttatgacga agcaggatat atcgcaatcc atattcacag cggacgaagc ggtcggaaca
    51241 ataaccatcg cagtatccgt gaagtgacga ttgtatctga catcatccat ttagtggaat
    51301 cagaattgga aacagatatc cattcagaac cattttcact gaattattca agactggtga
    51361 atcatttacg actgcttcta caacgaaccc atgcgcaaca atatgctgtt ttagacacgg
    51421 aaatcgtaga aatggtcaaa cgaaaatacc cagaaagcta taagatttct aaaaaaatcc
    51481 gtgtgttgct gaccaaagaa taccagctcg cgatcacgaa agaagaactg ggttacttgg
    51541 ccatccatat cgagcgttta agaagcgcaa tcgtacaaac aaatgttaac aatcatgagg
    51601 aggaaaaaaa ttgaaagcat atctacaacg aatgggacgt tcccttcaac ttccagttgc
    51661 ggtcttacct gctgctgctt tactagtagg gatcggaaac tggtgggcat cttatagtaa
    51721 cgacattgtc gctcattttt tacaagctgg cggtaacgca gttttaggtc aattaccttt
    51781 gctgtttgcc gttgggttag cactagggat gtcagtggac aaatcaggtg ctgctgcctt
    51841 ggcaggtttg gtcgcatttg aagttccagt aaatgtttta aaaactgatt cagtagctac
    51901 tttattgaat atcaaaccag aatcagttga tccatctttt gctcagatca gtaacgtatt
    51961 tattggtatt attgccggat tgattgcggc agctctttat aatcgtttcc acgaagcaaa
    52021 attaccgatg gctttatctt tctttagcgg caagcgtcta gtgccaatct tggctgcctt
    52081 tgtcatgttg ctgatcagtg cagtgctact gctcgtatgg cctccggttt actctgcttt
    52141 agtttctttt gctaaattca ttttgagttt aggctggggt ggtgcaggtc tttatggctt
    52201 cttcaaccgt ttactgatcc ctacaggatt gcatcaagca atgaactccg tgttctggtt
    52261 tgacgtagca ggaatcaatg atattggtaa atttttggct tctgaaggaa caaaaggcgt
    52321 aacaggaatg tatcaagctg gatttttccc aatcatgatg ttcgggcttc cagcaggagc
    52381 atatgctatt tacagaaatg cacgtccaga aaacaaagca aaaacagctt ccttgatgct
    52441 agcagcagct tttgcttcat tctttactgg tgtgacagaa ccacttgaat tttcatttat
    52501 gttcgttgct tggccattat atgtcttgca tgcaattttc actgggattt ctttagcagt
    52561 gagtgcattc ttccattgga cagcaggatt tgcctttagt gccggatttg tcgattactt
    52621 cctatctttg aaaaatccga ttgcgaatca gccattgatg ttgatcgtcc aaggattagt
    52681 aacagcagtg atttactact ttggctttaa ctttgctatc aaaaaattcc atctgatgac
    52741 tcctggccgc gaggaagcag atctttcaga tgacgatact gcaacgacta attcagacaa
    52801 taaatatgcg gcacaagcaa gcaaaatcta cgctgcatta ggcggagccg acaatgtaac
    52861 ttcgatcgat aactgtacta cacgccttcg tttgcaagtc aaagatacag gcctgatcga
    52921 tcaaaataaa atcaaagcca ctggcgtacc tggtatgaag atcatcgacg gaaaaaatgc
    52981 gcaagtcatc gtaggtacag aagtacaatt cgttgcagat gagatggcaa aactacatgg
    53041 tggtgctgca gcacgacctg cacaaacaaa caccgtggtt aaaacagaaa catttgccgg
    53101 tgaaacgatc gaacaagata tttacgctat cgcaaatggg aaactgattc caatcactga
    53161 agtttcagat gatgtattcg cggaaaaaat gatgggtgac ggctatgctg tattaccaga
    53221 aaatggagaa atcttctctc caatcgctgg tacgatcaca aacattttcc caacgaaaca
    53281 tgctgtcgga atccaaacag atgctggtat cgaagtcttg cttcatatgg gcatcaacac
    53341 tgttgactta aaaggcgaac cattcacttt atatgtagaa gaaggtcaaa aagtcgcaag
    53401 aggtcaattg attgctttag ttgatcttgc cgctattcaa tctgcaggca aaaacacgga
    53461 tatggtcgtt gtattcacaa atggcgacaa agtccaaagc ttagaaatcg aacccgcacg
    53521 tgatgtaaaa gcaaatgata aaatcggctc tgtttccaac aaagcctgag ccatcgtctt
    53581 ccccagactt ttttatcgat aaacaaacag gagctgagac aaaaatcttg tctcagctcc
    53641 tttttccgaa taaaaacggc gttctcctgc caactccgcg gtaataagtc cagctaaacg
    53701 aaacatatga agagctattt tttatttgac tcttcttatt acttgatgca gaacagcttt
    53761 ttcacaaaat ttttcttcat actcaaaact aatcggcttt ttcacaacct ctttatacat
    53821 tattcctgat ccaatatttc ttttaatgct gcttcaagag aagttaatgg ttttcccaat
    53881 actttttcta aatcatcaga ggaaatagct aactgatcct ttttaatatc atgttggatc
    53941 gctaaaaaca tgtcagctgc ttcttgaggg aatccggctt cttttagatt ttcgacaaac
    54001 gctgcatcac ttgcttcaat aatttctaac tctttacctg tcgcacgctc taatgccttg
    54061 gctaattctt catagtcagt tagattgccg gataattcta agatttctgg agagtcactt
    54121 tctactagta cttttgctgc agcttctgca tattcacgtt tcaatgccca acctgttttt
    54181 ccatttcctg cagcataaac gaattgacca gtttttaaag cctgcccaat gataggtaat
    54241 tcattctcta cataccaatt attccgtaaa aatgtatggg aaatacctga atccttaatc
    54301 attttttcag tgaattggtg atctggcgct aatacactga tcgagtgatc ggcatctgca
    54361 aaacttgtat aagcgatata agatacccca gctgcttgtg ctgccttcac tacattctta
    54421 tgttcggctt gacgatttcc tggaacgcca gagacaaaaa gcaatcgatc tattcctttc
    54481 aacgcttctt tcattgagtc taaatcatca taatcaccaa tacgtatatt aaatccagct
    54541 tctttcagtg cttctccttt ttcttcacta cgtactagta catagatttc attttgtgga
    54601 accatctttt ttaagaattc cagcgcataa ccaccaaaac ctccagttgc tcctgttact
    54661 aaataatgca tatttgccac tccctattct ttttatttgt taagatttac agctgtacat
    54721 ttataaatta cacctttatc ataaagagtg tggtaagata agtcaagcaa aaaaaatgaa
    54781 aggatgacaa ctgatgaagt attctctgca atttagtgat gcaatccatg tacttgccta
    54841 tattgaaatg tttcaagata cccgatcact ttctagtgag atgattgcca gtagtatcga
    54901 aacaaatgca gcaaatgtac gtaaaatcat gagtcagctc aaaaaatccg gtttgatctt
    54961 tacaaaaacc ggaaaaccgc agccttccct tgccaaaagt ccagatcaga tttctttact
    55021 agatgtctat cgcagcatcg aaggtaatac acagcttatc caagtcgatc caaaaacaaa
    55081 tccaaattgc gtcgttggtg cgaatatcca agaagcttta gaagaaagct acgctcggct
    55141 gcagaaaaag gcagaagaag aaatggctaa gatcacactt gatagtctga tacataaaat
    55201 agccgttttg gaaaaagaaa aaagaccaga aaacacaggc ctcgtagaga gatttttata
    55261 attctctcta ctgtgcctgc atttttctga tcggaatcgt ctacataaat tcttttattc
    55321 tccgggggac aaaagccttg tcatgcccct ttttcctctc taatgctcag gtcaaagcgc
    55381 tgaagtcatg acgtcttgat aaacggtgtt caagtagctg accctcggca ttagttctga
    55441 aaaatgcaaa atatggaaag ctatttccca tttttcctct ctaatgctca ggtcaaagcg
    55501 ctactttcac gacctctata ttatcatggt ttattgacta ccggtatcca gatttctccc
    55561 atatatttcc cgttggtaac tcccatttcg actacagcat ttggaccccc aacataggcg
    55621 taatcttcta cttctcttaa aacatgccca aaggccgtat tcgtcaaatc atttcttaat
    55681 tcttcaggcg attctgctaa agcgcttaca acaagatacg ttccttttgg gaatgggatg
    55741 attcgcgtag tgtttggaac atcctgactc gtttgaacac cgacatagta catcattttc
    55801 ccgttatagg gttcgttgac tgtaaagaaa taatgatttt cagcagcttg tttcaatgca
    55861 tctattgttc cattaccgat aactttttgc tcaaatgctt gtttctctgc agccaaaccg
    55921 acaaaatccg tattgctact cttcaattcc acaccaatac ccgtcaccgt aaaatctggt
    55981 ttttcttcga tcctatactt tgccatttct cccacccttt ctattatatt aagttcatct
    56041 tacataaaat taaagggaaa tgacacgatt acgctctttt ttctagggat atttttattt
    56101 tttaactatt tttttgcttt cactgcaatc caaatctcac tgtaaacatt actgaaatcc
    56161 tctccccatt ttgtaaaaga gatctcggga gcttcgacta acccataatc tgaagaagga
    56221 agccattctg catagatttt cccccaagta tcttgtaaag tttggggaaa tggcccttta
    56281 ttaggaaaaa tggcccaagt gtgttcttct atagcaagca tttctaaatc agcgtacgga
    56341 ttttcttttg tcgtagcaaa gccaatcatg tgcatcaaac tgcccttttc ttccaagcgg
    56401 tctccatcaa atccataaga aacgttgatt acttgatttg gatataaatc tcctaactta
    56461 tgcatctctt ccctttgagt ctccgtgatc gtctgcgcta acttttgtat ttcttgattg
    56521 actccttcaa atttgacagg aacttttttc gccacacctg ccacataaaa ctgttctttc
    56581 ttttcgatac gaaattccat cgattttcct cctctgacat caataaaaaa tgtcaagcgt
    56641 ggaaaagatt tttgtatgcc gtatctactg atttctgaag gcagatatcc tgaccaatca
    56701 cgaaaagctc ttgaaaaacc ttcgactgtt tcatatccat atctaaacgc cgtttctgtc
    56761 actcttgatc catctagaag atcgcgatta gccaaagcca atctacggtt tttgatatag
    56821 tccattagcg acatccctgc aataaacgta aagatgcgtt ttaattgata ttcagagatt
    56881 cctgtatttt cggctattat tttataggaa agtccttctg tcaaatgttc ttcgatgtaa
    56941 tcgatcaatt ggttcagatc tttaagcata tttatcttcc tccttgattg cctttttatc
    57001 atattatcaa agaaagtcaa ttacttgatg aatcaggaac caatttagtc agatgtagaa
    57061 aatgttgtat ggatctaaag aaaattctca agcagcgttt cgtaacggat aattggtatt
    57121 atctgcctat ctatgtttta cctttagaaa aataaatttt ggggaagaca gattctaagt
    57181 aaacaaagcg gtaaaaatat cttttattcc cttagttaat ccgcttacta cctactgtac
    57241 aaagcaaatt gttgttcaaa ctgctgatca gaacgctgct tggatttttc tttgcgatac
    57301 atcatacctc ttttatcaat tggaacaatt atttatttct aacaaaatca cttcattttt
    57361 gtcagataaa taaaaaacaa aaaaagttcc atctttaaaa cacgctattc ttttactttt
    57421 tctcacattc tctaagaaaa gaaaaggaga atgaattttt gacaattcga gcaaaagtga
    57481 ttatcaaata tgtaaaatca gctacttttt tcttaaacgt ttctttatac taaatataaa
    57541 taagtgtttc atgaaaggag aactagatga ataattggct tgagtatttt cctgaaaacg
    57601 ttttggaacg cggttacagc tatcatctgc acggttttgt ccgtcatttg aactatacaa
    57661 gcaagtactt gtccgcaaca gtttctggca cggaagatta taaggtagtg atcacttggg
    57721 atgaaaagac caacatgact tgtgattgtc tatatgccat agaaggaaaa aaatgcaaac
    57781 acatggctgc tgtcttattc gcttacgaag aacgtccaat aaaaaaatcc aactactcac
    57841 tttccgaact ctcgtccctt gtttcctccg ctagttcctc tcttgtacgg gagcttttaa
    57901 cagagattct tatagaacat ccgcacttta tcgaacgctt caaagttaag atgccatttc
    57961 atgcaataaa ttattcagat aaattaacaa ctatcatcca taaatacgat catattatca
    58021 agaaaaacaa aaacaggaaa acagcgaagt tcatcatgga gatgcgaaag ttcatccaag
    58081 aagcagttga atcgcttatt cagcaaaatg cctatcttcc cgcattcgaa ttgatcaatg
    58141 aagtgattgc tactctcgaa acattctatt gggagcctga ggatgaacga acccttcttc
    58201 tgatagagga ctgttattat ttatggaaag aattattagc agaagcacct catgcagaaa
    58261 aaaggcaaat gttctcttgg ttcgtctgcc aagtcgatca tactgacgcc tcttattcaa
    58321 aacgctactc tataaaaatc ctgaaagaag actttcggga aaaagaattt tctaaccaaa
    58381 agaaaaaaat agataaaaaa ctaaagaaac ggtaaagaaa gacgatttca atgaaaaata
    58441 gcaagtaaac gataacaacc atcctaaatc cacaagaaat acagcagacc ttgctttaaa
    58501 aacacgaatc atgcaaagga tgaagtaaag aagacttaac gcgtacccaa tattagtcat
    58561 ttgactatta ggtacgcgtt ttgttttata agtcatgaca aatttccttc gttgctggat
    58621 agattttccg gcattgttga tagattttat gatacttttc tacattttgt aagagaggtt
    58681 ccgctgcatc tgtatattgg ataaaattct gacaacaact ttcaggtgtg tcgaaccacc
    58741 ctaaccctag tgcagcaatc attgttgcgc ctaatgcagg tccttcctcc atacttaaac
    58801 aatagaccgt tgcatcgaaa atatcagctt ggatttgtag ccatgcaaga tttttcgcgc
    58861 ctcctcccac cgaaacaata cgtgtaaatc tgcgacccgc tagttcttta cgtttcaatc
    58921 ccaccattga caaatgctca ttaaaaattt agaatattca caagtttaac gacaattatg
    58981 aaaatttatg tcgtgctaaa ggagttttgt tattggatga aaagttagat ataaaaactg
    59041 cgatcaaaga cacgttacct accgttttcg gttatatcgg tattggactt gcatttggta
    59101 tcgttgggaa agctgccgga tttcatccac tagtcgtcac gttgatgtcc ctgctggtct
    59161 atgctggttc tgcccaattt atcacagtca gcatgcttgc tagtcacagc ccattgcttt
    59221 ccatcgtttt ctcgaccttt ctagtcaatt cccgaatgat tctgatgagt atgacgattg
    59281 ctccttattt caagaaaaat cggctgcttc aaaatctgct gattggcaca ttgctgacag
    59341 atgaaagttt cgcactggga atgaataaat tgaactatac tggacaaaag ttaaactttc
    59401 gttggatgaa tacagctaat tggatttctt atttgacgtg ggtgggttct tctcttgttg
    59461 gcgcactttt agggaatttt attactgatc cgaaaaagtt tggtttggat ttcgccatcg
    59521 tcgctatgtt tatcgggtta ctttatcttc aagtcatttc tgatagaaac acctctaaac
    59581 gattacagtt gatcctgatt ggtctcactt tgattctggt atatgtcgga ctgattttta
    59641 tcccaagcaa cttagtgatt gtagttgtaa cactgattgg gtgcggattg ggggtgtgga
    59701 tcaaacatgc cttcttttga gtttacattg ctgactattt taggttgtac tttagcaact
    59761 tggctttcta gggtcctacc atttgtctta ctgaaaaaat tcgatttacc gcaaccgttg
    59821 cttgagtatt taagttttgt cccgatcgtc attatgtctg ctttatggtt cagcagtcta
    59881 tttacccaaa atatcggaca tctgccgcag atcaatctcg aaaatgcttt ggcttcagtt
    59941 cctacacttt tagctgctat tctttcaaaa agcttattgg tgatcgtctt ggcaggaatt
    60001 ctttcccttt cgttgattcg cttattataa ataaaaaaac aagagcttat ggcaaattac
    60061 tgtcatgcgc tcttgttttt atcaaagtca aataagaaaa aaatcggcgt attcttgctt
    60121 atccgttgaa cggaccacta acaacgactt ttcctaacat atgtcctgtt tctacgtctt
    60181 tggttgcttg tttcaagttc ttcgcattca tcccatctga atagaccttg ctcaatgtac
    60241 tgcggataat cccttcattt gctaaagcag caatgtgcgc taaagcttct ccttgcgttt
    60301 cgatttcata gttatagtct gttttagcga acatatactc ccagtcgaag ctgatagatt
    60361 ggtttttcca aacacctata tctaacggct ctttgatccc tacgatcgtt cccacatgtc
    60421 caaatggtcg gacaaggtgc ttgatttgat caaagtagcg ggtaatatcg aataatacag
    60481 cgacatactc tacttgatcg attcctaatt cacgaaaact tttacttaag tcgtgatgat
    60541 aatcgattgg atagtctaca cctgtttttt tcagccattc aaaattcttc ggacttgcag
    60601 tcgcgtagac ttctaggcca gcccaatgcg ctagttgatt caaaatcgaa ccgacgcccc
    60661 cggatccgtt gatcactaag atttttttcc cgcgattggc attttcttct ggagttagac
    60721 caaatttttc aaataacaat tcataagcgg tcaatgaggt caacggcaag gctgcagctt
    60781 cttcatctga aagatttttt ggtgcaagag cgacaatacg ttcgtcaact agttggtatt
    60841 cttgattgct tcctgctctt gttgttgtac ctgcgtaaaa aacgcgatcg ccgacagaaa
    60901 atttttgcac ttcgtcacct acagcaacaa ctttcccgac tccatcaaaa cctaagatac
    60961 gtaaagcatt tcttatcccg ttatcttggc gaagtttcgt atcgacagga ttaacagata
    61021 ctgcgttgac ttttaccaga agatcccgtg aactgggtac aggtatctgt tctttttcat
    61081 caataaagct ttttggatca tcgatcggca acccttcata aaaaccgact accttcatta
    61141 attccttttc tgacatacga attcctcctt agcttcatca agttggagca tccatacagt
    61201 gttcatttca atatatatag tatgctattt gttccacctt ttttattcat cataattatt
    61261 ctcttactta aagtaaacta tttgcacttt tttggttaaa aaagaggttg cgacaagact
    61321 tttgtcacaa cctcttataa acggtgttct cctaccaact cttcggtcac aagtcaaaat
    61381 attcatcaaa catgagaagc tgttttttga aattgctcct tgtgactcag agttaaacgg
    61441 caggctcaca acctctgata taaacggtgt tcaatcaact gaccctcggt attagctcaa
    61501 aaaacgacaa aatatgaaga gctatttttg tttggctgtt cttattactt gatacaggac
    61561 agctttttca cgacctctaa ttcacggtgt tcaagcaaga aatcattgtt cactgaaaag
    61621 cgttggatgt tctttttcaa aggtctctaa gatctctcgt acttcatcag tagatttcgt
    61681 attcatcaac tgaactcgca agtcatttgc tcctggaaat cctttgatat agattttaaa
    61741 gaaacgatgt agtcctgtga tggaacgcgg gatgatttct gaataatgat cttgcagatc
    61801 tagttgcaga cgaagtagtc cgatcagttc tttttctgta tgttccctcg ggtctttttc
    61861 aaatgcataa ggattcttga aaatccctcg gccaatcatg atgccatcaa cgccatattt
    61921 ctcggccaat tcttctcctg tctggcgatc ggggatatct ccattgatcg tgattagtgt
    61981 ttgtggagcg atttggtcac gtaaagcaat gattttagga atgacttccc aatgtgcatc
    62041 tactttactc atctctttac gcgtacgcaa atggacagaa agattggcta tatcttgatg
    62101 aagtaggtga ctgatccatt cttccatctc agacatttcc gtatagccga tacgcgtctt
    62161 gacgctgaca ggcaaaccgc cagctttagc tgcttcaatc aattgtgccg ctacttctgg
    62221 acgaaggatc aagccactgc cttttccacg ttctgctaca ttagggactg ggcagcccat
    62281 gttgatatcg attccttgga agcccatttc tgccatagca atgctcattt ctctaaaaaa
    62341 ttctggcttg tctccccaaa tatgggcaac catcggctgt tcatcttctg taaatgttaa
    62401 tcttcctcgt acactgtctt ttccatctgg atgacagaaa ctgtctgagt ttgtaaactc
    62461 agtaaagaag acatccggtg ctgctgcatg ctttacgaca tggcgaaata caacatctgt
    62521 tacatcttcc attggtgcta aaacaaaaaa aggctttggc agctctttcc aaaaattagt
    62581 agtcatttat ttgttactct ccattctatc aagcagtgaa gtcgcaatct ttctcaaaaa
    62641 cattgtcatt atactaggaa acaaaaaaag aagcaaagtg aacagcttaa aagatgtttc
    62701 tgattgagca aaaaaaagac tgtgacaaaa atcttatcac agtccatttt ccggaataaa
    62761 tggtgttcaa aagcttgcat ttgcggtaat aagtccaacc aaacgaaaaa taggaggagc
    62821 tatttttgtt tggctgttct tattacttga tgcagaacag ctttttcaca acctctccac
    62881 taaacggtgt tcaatcagct gaccctcggt attcgctcaa aaaacaacaa aatatgagga
    62941 actattttcc cgtttgtttc tctaatactc aggtcaaaac gctgatttca caacctcttt
    63001 tctaacttct caatcctctt cctttattga tcaaatacca agtaacggcg tacaaaacaa
    63061 cgatgaataa cacaagtacg atcatcgatg ttgctactgg cacatcgatc gttccaagga
    63121 atccgtaacg gaaaccggag atcatataaa cgatcggatt gacttttgaa acagcttgcc
    63181 aaaagggcgg taacatagag atggcataga aaacgccacc tagataagtt aacggctgca
    63241 agacaaatgt aggcacgatc gatacatcat cataagactg agcaaaaatc ccgttgagca
    63301 gtcctgctaa tgaaaacaag attgccgtca tcaataatgt aatgatgacc atgaaccatg
    63361 aatacacatg aagtggtaca aagaacaagg aaatgatcgt tacgagagag ccgacgagaa
    63421 tactgcgacc cacaccacca atcacaaagc cccaaataat cacatgcgta ggaacaggtg
    63481 ctaccaagat ttcttcgata tttttctgaa atttttgaga gaagaaggac gaagaaacat
    63541 tggcatacga actagtgata gcagacatca taatcaaacc aggaacgatg aattccatat
    63601 atgaaaaacc acccatgtca ccgatccgcc caccgatcat ttttccgaaa ataacaaaat
    63661 acaaggatgt cgtgatcact ggcggaacca gtgtttggac ccatatacgc aaatagcggt
    63721 tcgtttcctt gatagctaaa ctttttaatg cagtaaaata aagattaaac atttttctcc
    63781 tccgtatgat tattttcttc tgtgattttc aagaacagtt cttctaaacg attcgactta
    63841 ttcctcatag aaagaacttt gattccttgt cttgtaagct gatcgaagat tccgttcacc
    63901 ccttgatttc gttcaacttc gacagcgatt gtctgctcat cttcaaatgt acaagcatat
    63961 ccttcaatca caggtttggt atcatatggc gctaaatcaa agataaatgt ttcaaattgc
    64021 agttttgaca gaagctcttt catacttgta ttctcgatca gttcacccga ttggatgatt
    64081 ccgatgttgc gacaaagcat ttcagcttct tctagataat gcgtcgtcaa aatgatcgtt
    64141 gtaccatttt cgttcaattc tcgtagaaac tcccacatct cgcgtctcaa ctcgatgtca
    64201 actcctgctg ttggttcatc caagatcagc aaacgtggtt catgcatcaa tgccctagca
    64261 atcatcagtc ttcgcttcat tcccccggaa agcatacgtg cacggacatt tctcttttcc
    64321 caaagattgg actgcttcaa atatttttcg ctgcgtttca tcgcttcttt gcgagagaca
    64381 ccgtagtagc ctgcttgatt cacgacgatt tgctggaccg tttcaaaagg gttaaaattg
    64441 aactcttgtg gaaccaatcc aatctgttgc tttgctcgaa ctagatcctt gtccagatca
    64501 taaccgaaga cattcacttt tccagatgtt ttattgacta aagaagtaat aatcccgatc
    64561 gttgtagact tcccagctcc atttggccct aatagcgcat agaaatctcc ttctttcacc
    64621 gaaagatcga ttccccgcaa tgcttcgacc ccacttccat agatcttttt caaattattt
    64681 atttcaagcg catttgccat ttatttccta tctccttata gacatgattc ttaattgtat
    64741 catggaatac agcagatgaa aaaacaactt ggcttccaca caaaaacaca cctgctaaca
    64801 aagaggagat gtgttttcta gttcatgatc atcttcgata gaataactat ctaaacaact
    64861 ctggaacttt taaaatcata aaagtaccga cagcaactac tacgatgaca tatagaagat
    64921 ccttataact gaggttcttg tcttttttat tcatgttaag ctttcctccg tccttttatc
    64981 gaaagctttt ttcttttatt ttaaccgaaa taaataaaat ggaaatagtt attttcaatt
    65041 tctgttttcg ctgtttgttt tacggagaac tttgccatgg aacgtgcgtc tcgtcgctga
    65101 tgctaagttt tttcgataaa agctgctaga aggaagacag cgtggtttat tttgtatcgt
    65161 cttttgctaa atcttccaag atcatctgga cagcagactc gttcccattg aattctgcca
    65221 cttttttggc atcaatgtac ttcttttgat aatcgtcttt ttggacccac gcatcatgct
    65281 tcgtttgata aagttaatca aacggatacc actgacgctg ttcatcgaac aacaaacttt
    65341 ctttttgggc ctgttcaact atggatttag gataattcaa aactttcagc aaggcaatcg
    65401 catttcgggt ccttgaaggt ccttctttta atttgaaatc aaaactgatt ccttttcctt
    65461 ctgttacttg ttcttcaaag tggacattct cacaataatt ctttaaaatc tctgtcaatt
    65521 cgatatcatg tgtggcgaca aatgctaaag atggatactc cgcaagccac cgaacgactg
    65581 aagcggaaga agcaatccgt tcgatcgtat ttgttccttt taaaatctca tctacgaagc
    65641 agtagcagcg ttctttggaa gccacttggt ccagcaaacg tttgatcgat ttgatttctg
    65701 aaacaaaata actgtcgcct tcaaataaat catcttcgat tgccatggaa gtcaacacat
    65761 gtccaggttg cagggtaaac tgttctgcaa tcgctgtttg gatcgtctgt gctagaatac
    65821 agctgatggc tatacttttg acatacgtag attttcctga tgcattggaa cccgtgacta
    65881 atgtattctt ctgccagttg actggattaa ctaccgcttc ttttaacaat ggatgataga
    65941 tatctttcgc tgtcacaccg ccctcagtaa actctggtcg gcaagtgatc ggcatatagg
    66001 tgcgataatt caaaacggct gctgcaactt ccaattctcc cagcaattcc cacagcttga
    66061 tggcttcagt tgaatgcttt tctaatttag tgagaacgaa atgataggag ataaatggca
    66121 gcatgaacat gatgttgaca tattcaaaaa tcaattctgc ttcactcccg ctcttcattc
    66181 gaaatgaaaa acctaattta gggatgtctc ttaatggttt agtttgctgt ttcagctctt
    66241 tttgaagtgg tgtcgtcatt tttgctaact gattggcggc tgaaatcgtt gaaaccaaat
    66301 aactcatgct attcagctct gtttctagtg tttgtttctt cactagataa tagaccgtat
    66361 tgaatactaa gccaccgatt gctagataga ttcctagtac ttgccctaaa agaagcaaac
    66421 ctacacccac cagcggaagc aagccaagaa aaataaataa acctacgcgt ccaatctttt
    66481 tactttttcc atccgctaga tattgttttg caaaattatg atcttttttt cctaaacgag
    66541 cgaattgata ttggattctt tctctcagtt gaggattttc ctgataaaaa gcaattagtt
    66601 tttctaactg ataatcttct ccaaaatcaa agctacgtaa acgctgatac aacgcttctg
    66661 aacctacact agaataggta ctgttgatcc cttcaaatac ttcgaacata tccaagtcat
    66721 accaagtaag atcgtcgatt tcactatccc atgaacggaa ttttttctcc gtgagccacg
    66781 catccttcaa actttcttct ttatcaaatc tcggttgata aggaattttt ccccaattac
    66841 tacgaactgt ttcctttact ttcaaacgtg aaaaaatgtc taaaacaact aataaaataa
    66901 caactgcaat aataattaaa acgataaatt ctctttggcc catatccctc tccgttcctt
    66961 gatttgttag ttttagtata gcactgttgc gctatttgaa aagggggtac aaaaataact
    67021 gtcttcgtta cctaattcgt atcaatcaca ccaaaataaa aacaccttcc aaaaaagaag
    67081 atgtctttaa aacgagatac aattttttgt cattcacttc aggtaaatta gagccaatta
    67141 aaccctccgc aacttgacgg agatggagaa gatgcccccg tctaatctag cggtcatctc
    67201 tcctcccatt ccttccacca atttttttga caggtaaagc ccgattccgc tagattccgt
    67261 atttgtgcgg ctggtatttt cggtataaaa acgctggaag actttttcaa cagaggtttg
    67321 cgctcctggt ttgataggat tggccactgt taatcgaatg aatgaatcct cttttgaaaa
    67381 tgtcaccttt gcttgtccat ctgcataacg caataaattc tgtatgatat tttgcagcac
    67441 tcgcagcaac atgagcggat ctgctaatac agttgtattt atcgagtgtt cagcgaacgc
    67501 tacctcgata tttttctcag aaaattgttc ataaaaagag aaaaatactt cttccacctc
    67561 tttagaaaaa gaaagcgtat ggagatccat ttctttttgc ttcgtctcta ttcgagcaag
    67621 atcataaaac tgatccgtca tactgagtaa tcttgcaaca gattgtttga tgatcgttaa
    67681 atacttctcc cgtttctccg tatcctctac ctgttccagt aattgtacat aaccgttaat
    67741 agcagtcaaa ggagttctga gatcatgaga aaggccgacg atcgatagtc tgatgttttc
    67801 ttccatttct tgaaatgctt gtcctttttg ttcattttca tccacccatg tattcagtgc
    67861 atctactagg tccattagat tcttttctcg aaattcgact gaaagacgac caccatattc
    67921 ttgtcgttca gaaagagtgg cgattttctt agttaatctc ttgatttccc tttgcaggaa
    67981 gaaaataaaa cttcccataa agataacaac gagaagcaac agccacttaa tcaaatctaa
    68041 accccactcc ccacaccgta tgaatataca cagcatgtgc ctttgctagt ttccctcgaa
    68101 gattggaaat atgcatattc actgttttct cactatcaaa atatggttct tgccaaactg
    68161 tttcataaag atttgctcgc gaaaatactt ttttcggatg ttctaaaaaa agcttcagca
    68221 gatcgaattc tcttcctgtc aaatggacag ccacaccatt cacatttaca tccctcgact
    68281 ctttgtccag taagatttcc ttgtaataga tgcgttgcga cagatctttt acttggacag
    68341 aagtctgatg acgaagttgg atgccgattc gtaacaacag ttcttcgata tcaaatggtt
    68401 tcgtcacata gtcatccgct cctgctgcca acaaggaaac tttatctctt tgatcgcttt
    68461 ttgctgaaag aacgatgatc ggaacattcg atgtctgtcg gatttctgct aacaatgctt
    68521 cacctgaaag ccctggaagc atgagatcta gaaggatcaa atcgacagga tatgtgctta
    68581 acaataattt tccttccgta cctgaataag catcaagaag tttgtatctc tgttcaagaa
    68641 cctcctccag taaagaatga acagcttcat cgtcttcgat aatcaaaata gtttccagca
    68701 ggaacaccta cttaatgtca gatttttgga aaataaacat tcctagagct gatgatacca
    68761 cgattgttac tagactgacc agaatcattt tcggtgcttg cgaataagtt gcttgttgcg
    68821 caaagtccgt atacatgagc cacgtttccg taaaccactc cgttagaaat tccaagcctt
    68881 tgatttttgc gaaaacaccg ggaacgaagg ccgttcccat gatataaaga aaagaaagaa
    68941 gcaaactgac actggtactt ctagtgatga atgtcaaagc cactggaaca gataatgtcg
    69001 ctaatatcag cagaagcaat acaggaaata cttttagaac ataatttcca tagtttttga
    69061 ttccctcaac ttcaccaaat ccgaaagcaa gtgtgtaagc aatcatggct agccccgtaa
    69121 tcaaaaccac gccaagtgtt gtgatcaaaa gcgtaacgag aagtttcgac acataataag
    69181 tcattcgatt ccgtcctaaa gataacgtat tgcgaatcgt accgttttga aattcttccc
    69241 caatataaaa gcacgcaaat gctgcgaaag ccagaagaat ccatgcagcc attttttcca
    69301 ccattaaaat ccctgttgca ccgttgatga ctgtatccgt tgcttggttt aattcattgc
    69361 cgtattttgt atgcatatac cattcgttcc aagaataaaa aagcggaagt acgaccatca
    69421 gtcctagtga gacccacatt ttacggctct tccatacttt tattttttca gcagttaata
    69481 gattaaacat gtggattgcc tccagttaat tgtaagaaat aatcttccag tttttgccca
    69541 actaggtgga taccatccac aggaactttt gcctctacca atgcttgatt gatggctgct
    69601 acttggtcaa ttccttcaaa aagctggata acacggctag attggacaaa ataatcccta
    69661 taaccaagag agtcgagaac cgttactgct tgttccgtcg ccgaagtgtc aatttttata
    69721 aattgacgag attcttgtgc caattcttct ttcgataatt ctttgatcaa gtgtccttca
    69781 tgcaaaatac cgtagtgagt ggcgatctgt gacaattcat ctagcaagtg gctagaaagc
    69841 aagacggtga tgccccgttc ttttaccaaa cgttggatga tttctcgcat ttctgccatc
    69901 cctgctggat ccatcccatt cgtcggttca tccaaaatca aaaattctgg attcgtgatc
    69961 agtgcatttg caatagctaa acgctggcgc atacctaaag agaaattctt tgctttcttt
    70021 ttccctgtat tttccaatcg catcattttc agcaggtctt cgatttctct atccgacaca
    70081 ccgccgttcg ctgcttggat acgtaggtta tctcttgcag ttaattctgg ataaagagca
    70141 ggggtttcaa tcgattgacc catacgtcgt cttgctgcct gcaaatccgt cgttccaaat
    70201 aattcgatcg aaccttcatc aatcgagatc aaacccataa tagttctcat aaaggtagac
    70261 ttacccgctc cattctcccc aatcaaacca tagatcattc cacgtttgat ttcgatcgat
    70321 actttatcta atgctttggc agcaccgtat tttttggtta taccagttgc tttcaagacc
    70381 gtttcatttc caaaatccat acttatcctt ctttcttatt gataagtgaa gtatagttga
    70441 cgggtataaa gaaagcagcc agaaatgtat aaagaaagtg taaattttcc aattgaattt
    70501 caagaaaaat cagactgtct cgcagacgtg gttgagttgt ctgccaatca aagagcgcac
    70561 caaacagtgc taatccaagt ggactggcca ccatggtaat cgttgttatc gttgacatca
    70621 gacgtccttg tatatgcgtt ggaacttctc gctgaagcca gaccatataa aaagcaaaag
    70681 aaaacattaa tccttaaaaa cggacttatg aaaaataata catgccgttt gggatttaca
    70741 attagctacc aaataagagg ttatgacaaa agacttttca caatcccttc ttccgaataa
    70801 acggtgttct cctgccaact cctcggtcac aagtcacaat atttatcaaa catgagaagc
    70861 aatttttgta aattccttct tatttcttga agctgaccac ttctgtcaca acctcagaag
    70921 cggataaata atattgtttg atgatacttt atctttttcc cgtttgttta tagatcgaat
    70981 gatattatag accaagaatc ctacctatta acatagctaa aaacacaaaa aaggcacttt
    71041 ccaaattgtg gaaagtgcca gaaaagttag gattaaggta actgcgctca gcattgcttc
    71101 gcccagtacg attctcgtaa ctcgtgaact cgaacgataa tcgcaattaa cgttttgaga
    71161 actgtgaagc tttacgggct ttcttaagac ctggttaaac aaaactctat tttattgcat
    71221 tttacaggaa tgtatttcat gcgaaattaa taagtctttg tttatagagt tttactaggg
    71281 tataaaaagt tgtatgttat cattacctca aaacattacc tcagcttggc gagttggttg
    71341 attgaagaat aaatcattta tctagatatc tcaataaaaa atgatttcta agaaacttgt
    71401 attttcgtgt tattattttt ttgccctatc aaaatttcta attcttctag cgtaatatga
    71461 ttatgacaca taatcgattc aattacttca atacctattt ttttcgagaa agatcccttt
    71521 tgttcactca caaaaatact ttcagaagac atatataagg aacgaagttt tggaattagt
    71581 atatcgtaca aatagaccac cataaaatcg tccttgcaac cattctcaaa aagaattaaa
    71641 tttgctgatt gtgttacata tatcactgaa ttacattcat ggtcaattcc aaaaacaatg
    71701 tctacttcat tttcttttct aattcgcgca gttacatttt tcaaactttc accattactt
    71761 ataaatgctt tagttactgt aagctctgat gtttgttcag atattccttt tataatattt
    71821 tgttcatcag ccacattccc cataaatccg ccgattcctt ttaagtaata attctcacct
    71881 aagagtcgct tgcattcact gaattgataa aaaaaccagt taaaaaaatc ttctggaaaa
    71941 ataaattctg atcgaacttt atttatattt ttagctccta ttaattttat aactcgatta
    72001 atgttcactt gctgcgatga acatataact gaataaattg agttgtttaa ttcaaaaaaa
    72061 caactttaac atatgcatca ttaattcgtt attttttagg tagatattga tcattgttat
    72121 ctctcttttt ttgcttccca tactccaact tagaaattgc cgttataaaa tttattttaa
    72181 aggtgacttt ttcccctgaa gtatcggtag taggaatact taatacctca gcttctgagg
    72241 aggtatccca attatagtta tactttgcat catcaccata aagaacaatt ccattttttt
    72301 tatcttgtgc cgttagcttt actggttcgc ttacttttct tgttaatatc ttggacttta
    72361 catcatcgat attgcttatt ttatcaagct taaataattt acaaattaat ttcgtactag
    72421 tttttatatt tgacgagagt gtaaaatatt ttgtgtaaat agaaaaaagg aagtcccttc
    72481 tgtagaatag agttaccaca acacattcac agaaaagagg acttccatat gaacgatttt
    72541 actacagaaa ttctaaagac tctagcgaac aaaggcgatt tgaatgaatt attccgtgtc
    72601 catttggaaa aagctgtcaa tacgcttctc aaaacggagt taacggcttt cctcgattac
    72661 gaaaagtacg atcgcattgg ttttaacacg gggaattctc gtaacggctc ctatgaccgt
    72721 acggtcaaga ccgagtacgg ggaacttcat ctccagattc cgcgcgaccg caacggcgag
    72781 ttcaagcaac agactgttcc tgcttataga cggacgaatg ataccttaga ggagaccgtc
    72841 attcacctct tccgaaaagg tattaccatg tcggaaatcg cagacttgat tgagaaaatg
    72901 tatgggcatc actacacgcc ccaaaccatg tccaacatga ctaaagtgct gactgaagaa
    72961 gtaaatgcat ttaaagttag aactctaaat gataagtatg tcgctatttt catggatgct
    73021 acttatattc ctttaaaacg gcaaaccgtc tccaaagaag caatctatat tgccattggt
    73081 atacgagaag acggcactaa agaagtacta agttatgcga ttgctccgac tgaatcgacc
    73141 tacgtttgga atgagttgtt acaggacatt tactccagag gggttcatga tgtcttactg
    73201 tttattaccg atggcttaaa aggcatgaaa gatacgattc accagattta tcctaaagct
    73261 aaataccaac attgctgtgt tcacgtttcc cgtaatattg ctcataaagt acgtgtcaaa
    73321 gatcgaaaag aaatctgtga tgattttaag gctgtttatc aagctagctc aaaggaagag
    73381 gcaaatacct ttttagggag tatgattgag aagtagcaaa aaacttatcc taaagtgacg
    73441 cagtcactga taaaaaatca agatttattg actttttatg agtttccgcc tggtatccgc
    73501 cgaagcattt actcaactaa tttaatcgaa tctttcaaga aacaaatcaa gaaatacagc
    73561 cgcagaaaag agcagtttca aaatgaagaa tcactagagc gtttcctagt atccatcttt
    73621 gatacataca atcaaaaatt cttaaataga agccataaag gcttccaaca agtgacggat
    73681 acattagctt caatgtttac tgagtaaccc attattttgc agaaggacga gttatttaca
    73741 caaaattatt gacgctccct ccaaattact tcatcaaaac attgatataa tttttattat
    73801 atcagtattt attcttgata cataaatgag aaaataaata ctttaaatct attgactaca
    73861 agtagtcatt aagtcttcat aagatgtaca atatgacatt aaaaaaataa aagcttacga
    73921 ccatccgtta aatctgacac taaataatgg actgctttct tttgtattag caggttacgt
    73981 tgactatgaa tattcaccag attatttgga gaaacctctt caacacgaga acaatgatat
    74041 taattttaga tttgtctacg agtcaaaaag taaaacatgg ttagttgatc aattaagcac
    74101 gataaacaca agcttccatg aattacctaa acctgaaaat gaagttgaga tggtcattaa
    74161 aatcttctaa aaaagaagcg ttgaagggga aatattcctt tcaacgctct tttttatatg
    74221 cttagaaaca taaataaatt gtatactttc tttttagccc ctattacttt tcacgaaaaa
    74281 tatctttttt tcgacgctag cgtttctcta cttctaatac tgtacacagt ttttgtatta
    74341 ttgaaaaatt actcattatt tagcattaat ccacatcgtt ttatcaatcg accttcatac
    74401 taaactactt taaagtcatc ttccttctcg tttttcatta
//
LOCUS       DADVXM010000006        73657 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.006, whole genome shotgun sequence.
ACCESSION   DADVXM010000006 DADVXM010000000
VERSION     DADVXM010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 73657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73657
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.006"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            162..392
                     /locus_tag="KB927_000460"
     CDS             162..392
                     /locus_tag="KB927_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBB6839405.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            489..1790
                     /gene="murA"
                     /locus_tag="KB927_000461"
     CDS             489..1790
                     /gene="murA"
                     /locus_tag="KB927_000461"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBB6839406.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1803..1979
                     /locus_tag="KB927_000462"
     CDS             1803..1979
                     /locus_tag="KB927_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBB6839407.1"
                     /translation="MSNQRYIILTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2114..2410
                     /gene="yidD"
                     /locus_tag="KB927_000463"
     CDS             2114..2410
                     /gene="yidD"
                     /locus_tag="KB927_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBB6839408.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2594..3061
                     /locus_tag="KB927_000464"
     CDS             2594..3061
                     /locus_tag="KB927_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6839409.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3146..4030
                     /locus_tag="KB927_000465"
     CDS             3146..4030
                     /locus_tag="KB927_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6839410.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4144..4380
                     /locus_tag="KB927_000466"
     CDS             4144..4380
                     /locus_tag="KB927_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBB6839411.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4468..4548
                     /locus_tag="KB927_000467"
     tRNA            4468..4548
                     /locus_tag="KB927_000467"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4502..4504,aa:Tyr,seq:gta)
     gene            4555..4626
                     /locus_tag="KB927_000468"
     tRNA            4555..4626
                     /locus_tag="KB927_000468"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4587..4589,aa:Gln,seq:ttg)
     gene            4751..4921
                     /locus_tag="KB927_000469"
     CDS             4751..4921
                     /locus_tag="KB927_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839412.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            5141..5848
                     /locus_tag="KB927_000470"
     CDS             5141..5848
                     /locus_tag="KB927_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6839413.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5908..6552)
                     /locus_tag="KB927_000471"
     CDS             complement(5908..6552)
                     /locus_tag="KB927_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBB6839414.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6679..6966
                     /locus_tag="KB927_000472"
     CDS             6679..6966
                     /locus_tag="KB927_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839415.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7074..7394
                     /locus_tag="KB927_000473"
     CDS             7074..7394
                     /locus_tag="KB927_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6839416.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7475..8788
                     /locus_tag="KB927_000474"
     CDS             7475..8788
                     /locus_tag="KB927_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBB6839417.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8785..9504
                     /locus_tag="KB927_000475"
     CDS             8785..9504
                     /locus_tag="KB927_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBB6839418.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9632..10183
                     /gene="raiA"
                     /locus_tag="KB927_000476"
     CDS             9632..10183
                     /gene="raiA"
                     /locus_tag="KB927_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBB6839419.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10405..12939
                     /gene="secA"
                     /locus_tag="KB927_000477"
     CDS             10405..12939
                     /gene="secA"
                     /locus_tag="KB927_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBB6839420.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDIQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGDE
                     DAVIQSKMLTKQVEAAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIVDFAGSTLVHEDSISLTDIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKDAN"
     gene            13066..14167
                     /gene="prfB"
                     /locus_tag="KB927_000478"
     CDS             join(13066..13137,13139..14167)
                     /gene="prfB"
                     /locus_tag="KB927_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBB6839421.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAVMQEEAEARI
                     NALDEKMNTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14272..14958
                     /gene="ftsE"
                     /locus_tag="KB927_000479"
     CDS             14272..14958
                     /gene="ftsE"
                     /locus_tag="KB927_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBB6839422.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14942..15835
                     /locus_tag="KB927_000480"
     CDS             14942..15835
                     /locus_tag="KB927_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6839423.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEKAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFYQLINPSLLRSHYSLIHPENIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            15987..17435
                     /gene="cls"
                     /locus_tag="KB927_000481"
     CDS             15987..17435
                     /gene="cls"
                     /locus_tag="KB927_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBB6839424.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDTLGE
                     EVREALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPEFFPTIHSTGDMAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEVYENRGMMIKMKEGLARLISPLL"
     gene            17772..18629
                     /locus_tag="KB927_000482"
     CDS             17772..18629
                     /locus_tag="KB927_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBB6839425.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQAENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18744..19664
                     /gene="pstC"
                     /locus_tag="KB927_000483"
     CDS             18744..19664
                     /gene="pstC"
                     /locus_tag="KB927_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBB6839426.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19664..20548
                     /gene="pstA"
                     /locus_tag="KB927_000484"
     CDS             19664..20548
                     /gene="pstA"
                     /locus_tag="KB927_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBB6839427.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20563..21369
                     /gene="pstB"
                     /locus_tag="KB927_000485"
     CDS             20563..21369
                     /gene="pstB"
                     /locus_tag="KB927_000485"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBB6839428.1"
                     /translation="MKKYNWNETNVITMPKDKEVALYTNDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYKDVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21385..22143
                     /locus_tag="KB927_000486"
     CDS             21385..22143
                     /locus_tag="KB927_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBB6839429.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWEDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22156..22833
                     /gene="phoU"
                     /locus_tag="KB927_000487"
     CDS             22156..22833
                     /gene="phoU"
                     /locus_tag="KB927_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBB6839430.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23055..24089
                     /locus_tag="KB927_000488"
     CDS             23055..24089
                     /locus_tag="KB927_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBB6839431.1"
                     /translation="MQKKISIIITLFFICILASWFIQRQAALYDVPVIEIERVRIEED
                     QQLITGRLMNTDQKGEVISLTAPYQKNQIETANITTRQIYLVQMHGDEWQLVAKKNDG
                     WLFFFTSVFIGTMLLIGGKQGVFALGSLIINIVLLLLLLLLFTKTEGISLLNIAILFV
                     VIGIIVSILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTR
                     PYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKQQPKISAKQLWLSGRQVGRDVIGS
                     MANILLFVYISGAIPSLLLYLGNQWSFKETVERHLSLELLRVIAGSLGIVLSIPIAVL
                     FFLAVRRLKK"
     gene            24086..24853
                     /locus_tag="KB927_000489"
     CDS             24086..24853
                     /locus_tag="KB927_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBB6839432.1"
                     /translation="MNVLIILVGIFAISVLFVGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILVLSIIGFLLIAVVILFFINGYNLKMRAAFASILIFLFCFLLLIPITDFLAI
                     QGFTSIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     MSFNQLRHASFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDISFQQIINEKSFVL
                     EYTMAILTTLAALLVLPLTCVTTAYLFTKKKEHLKME"
     gene            24953..26521
                     /gene="liaX"
                     /locus_tag="KB927_000490"
     CDS             24953..26521
                     /gene="liaX"
                     /locus_tag="KB927_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBB6839433.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDELENGEEKISEPVDPKEKERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEATGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSDDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVNQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATPENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDSIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26697..27005
                     /locus_tag="KB927_000491"
     CDS             26697..27005
                     /locus_tag="KB927_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBB6839434.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            27005..27355
                     /locus_tag="KB927_000492"
     CDS             27005..27355
                     /locus_tag="KB927_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBB6839435.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
     gene            27521..28459
                     /locus_tag="KB927_000493"
     CDS             27521..28459
                     /locus_tag="KB927_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBB6839436.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28474..29304
                     /locus_tag="KB927_000494"
     CDS             28474..29304
                     /locus_tag="KB927_000494"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBB6839437.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGSLPDYDRSLGKNQQII
                     "
     gene            29348..30373
                     /locus_tag="KB927_000495"
     CDS             29348..30373
                     /locus_tag="KB927_000495"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBB6839438.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTNV
                     KAAKYVQELFMNHYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30388..31326
                     /gene="galU"
                     /locus_tag="KB927_000496"
     CDS             30388..31326
                     /gene="galU"
                     /locus_tag="KB927_000496"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBB6839439.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            31451..31900
                     /locus_tag="KB927_000497"
     CDS             31451..31900
                     /locus_tag="KB927_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBB6839440.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFLKTKNILKRQEENKNG"
     gene            31893..32507
                     /locus_tag="KB927_000498"
     CDS             31893..32507
                     /locus_tag="KB927_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBB6839441.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(32570..33673)
                     /locus_tag="KB927_000499"
     CDS             complement(32570..33673)
                     /locus_tag="KB927_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBB6839442.1"
                     /translation="MNNVKINELRQWMAQHQLELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            33883..34884
                     /gene="ccpA"
                     /locus_tag="KB927_000500"
     CDS             33883..34884
                     /gene="ccpA"
                     /locus_tag="KB927_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBB6839443.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            35238..35633
                     /locus_tag="KB927_000501"
     CDS             35238..35633
                     /locus_tag="KB927_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839444.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREAQKQQDLLAVEKQS
                     VKVLKNTFADIKEVKIEQFEKNDMTGIYEALITMTNTEGKAVYFDYSFTKESNEIDGY
                     GVENEEVQKEGITVDEIIVIYTDGSEEKV"
     gene            35630..36886
                     /locus_tag="KB927_000502"
     CDS             35630..36886
                     /locus_tag="KB927_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HBB6839445.1"
                     /translation="MTITDKQYKGISNKVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKNSFDGMQAMAVAPIKNGKVDISQVVIAFAGTNLSDWKDLETDARSVMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAYLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSVKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            36898..37221
                     /locus_tag="KB927_000503"
     CDS             36898..37221
                     /locus_tag="KB927_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839446.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            37214..37480
                     /locus_tag="KB927_000504"
     CDS             37214..37480
                     /locus_tag="KB927_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839447.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQTWAEKRLTDQNHQ
                     MTAEEATQEFSNRHAHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(37643..39988)
                     /locus_tag="KB927_000505"
     CDS             complement(37643..39988)
                     /locus_tag="KB927_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBB6839448.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKDEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            40267..41169
                     /locus_tag="KB927_000506"
     CDS             40267..41169
                     /locus_tag="KB927_000506"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBB6839449.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            41380..43155
                     /locus_tag="KB927_000507"
     CDS             41380..43155
                     /locus_tag="KB927_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBB6839450.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPTVEIIIA
                     CLLAIYYRKYNSSKKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFDFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLKLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVIGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIAVTSMLVFSKLNLKKALSSK"
     gene            complement(43464..45050)
                     /locus_tag="KB927_000508"
     CDS             complement(43464..45050)
                     /locus_tag="KB927_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBB6839451.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            45301..45525
                     /locus_tag="KB927_000509"
     CDS             45301..45525
                     /locus_tag="KB927_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBB6839452.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            45667..47418
                     /locus_tag="KB927_000510"
     CDS             45667..47418
                     /locus_tag="KB927_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6839453.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            47418..49202
                     /locus_tag="KB927_000511"
     CDS             47418..49202
                     /locus_tag="KB927_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6839454.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            49537..50388
                     /locus_tag="KB927_000512"
     CDS             49537..50388
                     /locus_tag="KB927_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6839455.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQNNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            50485..52371
                     /locus_tag="KB927_000513"
     CDS             50485..52371
                     /locus_tag="KB927_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6839456.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLKAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(52412..53314)
                     /locus_tag="KB927_000514"
     CDS             complement(52412..53314)
                     /locus_tag="KB927_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6839457.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            53544..54947
                     /locus_tag="KB927_000515"
     CDS             53544..54947
                     /locus_tag="KB927_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6839458.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMATMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     DLIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            54944..56380
                     /locus_tag="KB927_000516"
     CDS             54944..56380
                     /locus_tag="KB927_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6839459.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDKDHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     ENEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDTVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            56525..57451
                     /gene="trxB"
                     /locus_tag="KB927_000517"
     CDS             56525..57451
                     /gene="trxB"
                     /locus_tag="KB927_000517"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBB6839460.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            57665..59392
                     /locus_tag="KB927_000518"
     CDS             57665..59392
                     /locus_tag="KB927_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBB6839461.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLIDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            59408..59758
                     /locus_tag="KB927_000519"
     CDS             59408..59758
                     /locus_tag="KB927_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBB6839462.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(59852..60712)
                     /locus_tag="KB927_000520"
     CDS             complement(59852..60712)
                     /locus_tag="KB927_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBB6839463.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            60804..61232
                     /locus_tag="KB927_000521"
     CDS             60804..61232
                     /locus_tag="KB927_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6839464.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            61394..61570
                     /locus_tag="KB927_000522"
     CDS             61394..61570
                     /locus_tag="KB927_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBB6839465.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            61597..62043
                     /locus_tag="KB927_000523"
     CDS             61597..62043
                     /locus_tag="KB927_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBB6839466.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(62199..63578)
                     /gene="brnQ"
                     /locus_tag="KB927_000524"
     CDS             complement(62199..63578)
                     /gene="brnQ"
                     /locus_tag="KB927_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBB6839467.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            64284..65255
                     /locus_tag="KB927_000525"
     CDS             64284..65255
                     /locus_tag="KB927_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBB6839468.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            65279..67471
                     /locus_tag="KB927_000526"
     CDS             65279..67471
                     /locus_tag="KB927_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBB6839469.1"
                     /translation="MLNKTLQKLQKKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            67488..67964
                     /gene="ybeY"
                     /locus_tag="KB927_000527"
     CDS             67488..67964
                     /gene="ybeY"
                     /locus_tag="KB927_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBB6839470.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            67948..68343
                     /locus_tag="KB927_000528"
     CDS             67948..68343
                     /locus_tag="KB927_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBB6839471.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFSVIVGLILFVPKIYHLLFN"
     gene            68358..69257
                     /gene="era"
                     /locus_tag="KB927_000529"
     CDS             68358..69257
                     /gene="era"
                     /locus_tag="KB927_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBB6839472.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            69400..70212
                     /gene="recO"
                     /locus_tag="KB927_000530"
     CDS             69400..70212
                     /gene="recO"
                     /locus_tag="KB927_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBB6839473.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTSEKDMSEKDLPKKEE"
     gene            70598..71515
                     /gene="glyQ"
                     /locus_tag="KB927_000531"
     CDS             70598..71515
                     /gene="glyQ"
                     /locus_tag="KB927_000531"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBB6839474.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            71517..73592
                     /locus_tag="KB927_000532"
     CDS             71517..73592
                     /locus_tag="KB927_000532"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBB6839475.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        24156 a        12996 c        15838 g        20667 t
ORIGIN      
        1 ttttgtctca gtcccttttt ttgcatattt ttagcattta tttcctaaaa aatgtaaggg
       61 gattcctata tttttaagta tacttgtttt tccttttata cattttatgg tattatcatt
      121 ttattagtta ttataaaaca atcgttagaa aggacgtcat tatgcaagta tacggaattg
      181 atgcggtgct tcgaatcgtg agtcatttgg cgtttatcta cttagccttc tggtctttac
      241 gttcgttacg cattgaaact tttttcagac caatgcataa tacgcaaatt agaatggcaa
      301 tcgtactttt ttcaattttt ttagggtaca ctgcaagtaa ttttttctta gaagttatcg
      361 ctttatgccg aaatcttttc gttagcctgt aaattttaaa aaaaggtact attttaaaag
      421 caaggatgtt ataatagaaa agattttgag taagtgtatg ctcattggaa ttttttggag
      481 ggaacaacat ggaagagatc atcgtaagag gtggcaatca attaaatgga acagtaagaa
      541 ttgaaggagc taaaaatgct gttttgccta ttttagctgc tagtttgtta gcagaagaag
      601 gtattacgac attagacaac gttccgattc tttctgatgt cttcactatg aatcaagtga
      661 ttcgtcactt aaacgtagat gtagattttg atgaacaaaa gaatcaagta acaatcgatg
      721 cttcaagaca attagaaatc gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa
      781 tcgttgtgat gggtccgcta cttgccagaa atggacatgc aaaagtagct atgcctggtg
      841 gatgtgcgat tggtaaacga ccaatcgatt tgcatttaaa aggatttcaa gctttaggag
      901 caaaaattat tcaaaaaaac ggctatatcg aagcaattgc ggatgaattg atcggtaaca
      961 cgatttattt agatttccct agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa
     1021 aagcaaaagg aacaaccatc attgaaaacg tagctcgcga accagaaatc gttgatttag
     1081 caaacatttt gaataaaatg ggcgctcaag tctatggagc tggtactgaa acaatgcgta
     1141 ttgaaggcgt ggatcattta catgcagtca accactcaat cgtacaagat cgtatcgaag
     1201 caggtacctt tatggttgct gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta
     1261 tctctgaaca taaccgccca ttgatttcta aattgatcga aatgggtgca gaaatcattg
     1321 aagaagaagg cggagtccgt gtcatcggac caaaacatat cttacctaca gatgtaaaaa
     1381 cgatgcctca tcctggtttc cctacagata tgcaagctca aatgacagct atccaattag
     1441 ttgcagaagg tacaagtgta gtgactgaaa cagtgtttga aaatcgtttc caacatttag
     1501 aagagatgcg ccgtatgaac gctcatgtca aaatcgacgg aaatgtagca atcatggatg
     1561 gaaaccatga attgcaaggt gcagaagtat atgcaacaga cttgcgggca gcagcagcat
     1621 tagttttagc tggcttgaaa gcaaatggaa tcacacgtgt gcgtaacttg aattatctag
     1681 accgtggata ttataatttc catatcaaac tacagcaatt aggtgcagac gttgaacgtg
     1741 tagacatgga tcaaacttct gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct
     1801 gaatgagtaa ccaacgatat atcatattaa ctttgataaa gattttagtg gtgatcttat
     1861 tgcttatcct tctttttgtg gccggaacga tgatcggata tggtgtcatc ggtggcggca
     1921 atccatttaa agtattccag ccaagtttgt ggattcatat tcgagacttt tttcattgat
     1981 aaataagaat cacagtggtt ctagtcgata tgaagtgagc catgaagcag aacatgacaa
     2041 aagaaaacag aagggaacgt tgacgttagt cgcgatccct ttttttagta aaagaaaaga
     2101 aggaatctaa ttgatgaaga agatattgat ttatttagtt agaggatatc agcgctttat
     2161 ttcgcctgca tttccaccta gctgccgtta ttacccaacc tgttccaatt atatgataaa
     2221 agcaattcaa acccatggtg cactaaaagg gacggtaatg gggactgcac ggatcttacg
     2281 ctgtcatcct tttgtcaaag gcggtatcga ttatgtacca ttgacattcc aattaacgcg
     2341 aaataagaaa gataaaaaag aaccagatta taaaaaggtt gtgaaaaata cgagtagcac
     2401 tgagcgataa agaaacaatt tggaaaatag cttcttatat tttgcaaaat tgtgagttat
     2461 tgccgaagtg ttggattttg aacaccgtca aaaaaaggtt gtgaaaaata cgggtagcac
     2521 tgagcgataa agaaaaagag gaaaattatt gtcaaagtaa caactccgca actacttata
     2581 tgggggacaa aaaatgatcg aagaactaaa caagaaagat ttaccatggt ccttgttatt
     2641 agatgcagat cctgataaag aaaaagttca agtatatgtt tccagaggga gtggctggat
     2701 atggaaagaa aaagaaaaaa caataggtgt actgatctat gtggcaaggg aaaaagaata
     2761 cgaaatcgtc aatgtagcag tagccccaac gtatcaagga aaggggattg gcggaaaatt
     2821 acttgagaca gcttttcaga agctttcaca actcgcttcc agtcaaactc agatcatcat
     2881 acgaaccggc agtactagca gtgcggcgtt acatctctat caaaaaatgg gctatgtgga
     2941 gattggtcga gtcaaagact attttatcca tcattactct gagcccattt ttgaaaatgg
     3001 agatcaatta agggatcaag taattttagc aattcactta cctaaaaata gctttaacta
     3061 ataaactttc aattcgagaa aatgctttca aatgctaaat agatacatta caatagcttt
     3121 agcaaacaaa aaggagaata tttttatggg aatattagtt tttgattttg gtggatcggc
     3181 tgtcaaatat ggttgttggg atggcaaaga gattaaaggt aagggacaat ttgcaacgcc
     3241 tgaatcttgg gaagaaatga aagcgcaatt atttcaagtt tataaaaaaa tactcgtttc
     3301 ttttgaagtc gaaggaattg gaatcagctc tcctggagta gtgaataatg agaaacaggt
     3361 gattgaggga atcagtgcga ttccttatat tcatggattt aatattttcc gagatttgga
     3421 aactctgttt caactcccag taacgattga aaatgacgcc aactgtgccg gaatggctga
     3481 attttatgaa ggtgctgccc gtgattatca agatgttgct tttgttgtgg caggaactgg
     3541 gattggcggg gcgttgttca cgaaaggaca aatcaataaa ggggcacatc tttatggtgg
     3601 agaatttggg ttgatgttct taaatggcga taagacattc agtaaacttg gtacagcggt
     3661 acagatggct tggcgttatt gtgaacgcaa aggtctcgat aaaaattctt ataccggaaa
     3721 agatgtcttt gaattagcag aaactggaga tgcaatagca aaagaagaag ttgagagttt
     3781 ttatacgtat cttacaaagg gattattcag tattcaattt tcgtttgatc cagaagtgat
     3841 cgtattaggc ggcggtgttt ctgcaaaaga agggctcatt gatgagatca aaagccgaat
     3901 gaagaagctg acagaacaat tcgatctgca tgatttcgaa ccgcagattt tattatgtga
     3961 atacagaaac gatgctaatc ttgtaggtgc agcagcaaac tatctcgctg tacgtcaagg
     4021 ggagaattaa gagctttaga gaaggtgcag cttgcataaa agaagtgaat gaaatgaata
     4081 ggagattttt acctaaggaa tgttttattt gctgcagtat gataaaatat ctgagaggtg
     4141 aaaatgatgt caaaaaaaaa taaagatgtt gaagtgcgta tagaagaagt gaaaaaagat
     4201 atcaaaggta agaattatga agtcactcag ttatttatag ggaaaaaaat gattggtgag
     4261 atcttagcct atgggccaaa agaatatgaa attttctttg gtgaagaaga ttttggaaaa
     4321 gaaaaaagtc ttgaaaatgc gatagaaaca gtgattcgac actggaatct gcacgaataa
     4381 aaaaatatca aaaaaacttt caataaaggg ttgcaaaaat ctggaaaatt aggtattata
     4441 actaagtcag gttgatacaa acctttcgga ggagtagcga agtggctaaa cgcgacggac
     4501 tgtaaatccg ttccttaggg ttcagtggtt cgaatccact ctcctccatt tcattggggt
     4561 atagccaagc ggtaaggcaa gggactttga ctccctcatg cgttggttcg aatccagcta
     4621 ccccagtata ccacaatcgt aagctctcgt tagttcgaga gctctttttt ttgctttgct
     4681 accttgttcc ttgaagattc tgctgattta agatagagtt aagttaacta caagaattgg
     4741 agggatccac atgaaatgga aagaaaaagt agacgaagca gctgaaaagt tatatgattt
     4801 ggtcaaatca gaaaaataca atattgaagt gaatattccg aaaaaaggcg gaaaagcggt
     4861 ccaggtaaaa tcaaaacgcc caacgaatca tacaaaaaaa tggatggcta aaaaccgcta
     4921 ataataacaa aagatccata agtcggcatt ttcatcgatt ttagggtctt ttgttatttt
     4981 ctaggttgaa catatctaaa aaattgtttc tgacaatagg agtaggaaga acgatgtgtg
     5041 tctaaatcct ctgttgatgg atagaaacct ttatcttttt cagttgtgaa tcaggtatat
     5101 accagttata atagaagaaa cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt
     5161 atatatacag attcatgacc aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg
     5221 agaccgtctt ccttcagaaa gagaattagc agtgaaattc aatgtcagcc gtatgacgtt
     5281 gagacaagca attcaaaact tggcagatga aggaatctta gaaagaaaga tcggttcggg
     5341 tacatatgtt gcgcgagaaa aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga
     5401 aattatggaa tcgcaaaatc gagtaccgtc tagtcggaca atctcttatt tcttgacttc
     5461 gccaagctca agtgaaatgg aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat
     5521 ggaacgtatt cgtttcgcag atgatgtccc tatttgtttt gaagttgcca gtgtgccaca
     5581 aaagctgatc gatggctaca gcaaagcaga gattactgaa tcgttgtatc gcacgctaga
     5641 agaaaaaggc gggaaaaaga tcggtccagc gaatcaaacg attactgctg tgttggcttc
     5701 tgagaaaatt gctgactatt tagaggtaaa acgaggagat gcagttcttc gtttgcgcca
     5761 gatttcttat tttgaagacg gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa
     5821 tcgttttgag ttttatttgg aaaaataaaa aacaggtgat ccctgattcc ttacttagaa
     5881 ataaaagaga atcagaatca cctgttttta tatatgatca gttaccagtt gctcgtgata
     5941 agaaacagga ccctcttcaa attggacttg tccgttcagc agctcaatga tggattcttt
     6001 aaagtggtca gcactttttt catctacagc acagatgacg ctaacttgat cagtatattg
     6061 gatttctttt ataaaaaaat gttggagttc aagataattc tgtaattttc ctagttgcgg
     6121 atacgtgatc atcacagaga tctcctgttg caaggtacct tctacgattc caatgtcaga
     6181 caatgcttga gagacagcat gagtgtatgc tcgtattaat ccgcctgtgc cgagtttcgt
     6241 tcctccaaaa tatcgagtga ctactgcagc tacattgatc agttgatttt ttttgaggac
     6301 ttccaacatc ggtacgccag ccgttccact tggttctcca tcatcgctgc ttcgctggat
     6361 ttcatttttt tctccaatga tgaaggcgct gcagttatgg ttcgctttcc aatgttcttt
     6421 ttttatttct tgaatgaaac tttttgcttg gtcctctgat tctattcgtc taagagaaca
     6481 gataaagcgt gattttttga tctcaatctc actttgtcca ttttctttta ttgtacgata
     6541 gcgctcgatc atcttgtcac ctcttttttt cattttcttt attcagtata aataaagttc
     6601 taggttgttt caacactgta acggttgcgc aatcgctgta gtatgcgata ataaagacaa
     6661 aggtaggtgg atctggggat gcaggaacga atgaaaaagt acgatgcaat tacgcattat
     6721 ttgaagaaca atggcggctc tcaagtaacg ttgaccttta cccaatttga cgaactgctg
     6781 tttcccagta acggacttcc caaaacagca agggaaagta cagattggtg ggcaaatgat
     6841 tataaacacc ctgaaaaagg tgcctatggc tggataaatg caggctatga agtagttgtc
     6901 atcaatttgg acaaagaata tgtcgtgttc aataaattag tgaaatctag ttggctattt
     6961 gattaaataa accgcgttta gaaaacgttg acaaatttct ttctttttat ataatagagt
     7021 aacagacgcg aagaaaacgt ttgcgtagtt tgttttaaaa aggagagaaa agtatggcta
     7081 aaaaaacaat catgcttgta tgttcggctg gtatgagcac aagtttacta gtaacaaaaa
     7141 tgcaaaaagc tgctgaagca aaaggaatcg actcggatat tttcgctgtg tccgcttctg
     7201 acgcagataa caatcttgca aataaagatg tagatgtact gttattagga cctcaagttc
     7261 gctttatgaa agctgatttt gaaaaacgtc tggaaccaaa aggcattcct ttagacgtca
     7321 tcaatatggc tgattatggt atgatgaatg gcgaaaaagt gttagatcaa gcaatcacgc
     7381 tcataggtga ataaatagaa cagtataact atcgaacaag cgatccaaaa aatagatcgc
     7441 ttgttttttc gtatattttt ttagggcgaa taatatgaat catttttggg gtagaaggct
     7501 tctgacgaga gatattaaag caatagactg tgaggaggta aatttaccaa attatgagaa
     7561 gatcgcagca gtggaacgtt tgggcaactg gattctttgt catcgctgtg gaatgaggac
     7621 gtccgtcatt gatggacagc ttgcagatta cggttatttt tgtacacatt gtctatattt
     7681 agggcgatgc gacactcaac aagatttata tttgtttgat cagcctgaag caaaacctcg
     7741 agaagtcgtc tttttttgga caggacagct tactgaaaaa caaacggaaa tcgcaaagag
     7801 aatactttgc cattcagaaa aaagacatca tcttatttgg gctgtaacag gtgcagggaa
     7861 aacagagatg ctttatccta ttttagtgga aactttaaaa gctggaggaa gagtagcgat
     7921 ttgtacaccg cgagtcgatg tttgtaatga attgttttta cgctatcgtt atgtttttcc
     7981 agaagaaaaa atcacgttgc tccatgggaa tacagcaacg gcttatacct ttacttcttt
     8041 tgttatctgt acgattcatc agctataccg tttttatcgg tcctttgatt taatagtgat
     8101 cgatgagatc gatgcgtttc cttataacgg ggatgcagga ttagctcatg ctgtgcaaac
     8161 agcgattaaa ccagacggac gattcatcta cttaagtgcc acacctgata aaaagttact
     8221 aaaggaaatc aagcagacgt ttgacatcca caaacttgct ttgcgctttc atcggcgttt
     8281 acttcctgaa cccgtcttgg ttttcatgaa taattggcga caaaaatgca agaacaagaa
     8341 gaagataaaa tctttggtgc ggatcattca tcaattaatt aaagaaaacc atatcctttt
     8401 attttgtcca agtatcacga tgatgcatcg tttgaaagcc acacttcaag aggctcttcc
     8461 gagatatgag atcacagatg tttcttcaag agacaatcag cgggcggaaa aagtccagaa
     8521 aatgcgagaa gcaaaatatg acatactgtt aaccacgatg atccttgaac gtggagtcac
     8581 atttgaaaga atatccgtta tcgttttagg agcggatcat ccggttttta ctaaatcttc
     8641 tttggtacaa atcgcaggaa gagccgatcg taaagggcct tatacgaaca gtcaagtata
     8701 ctttttctat gaagaaaaaa ctgcagctat tcgaaaagct tgtcaggaaa tcaaagaaat
     8761 gaatgaagaa gggaagaaga tgctgtgagg tgcagttgct gcagtaaaga tatcgtccaa
     8821 aatttaacat tcagcgagat tattggtgtt tcgaaataca gattacctca gacttgttca
     8881 gtttgtcgcg cacaatttca tttattggaa acaagaggct gttctggctg tcaaaaacca
     8941 atccatttca atctagagag tacgaaaaag aaagtaaagt ctattcccgt ttactgcagt
     9001 gactgtcaag aatggaagaa gaaatatccg acctatgatt ttcagcaccg tgcctttttt
     9061 gtgtacgatg aaaatatgaa ggcctggctc aatcaataca agtttatggg agatatccga
     9121 ctagcaggca cctttgcata taaatggacg cagataaaaa aagaataccc gacatacatc
     9181 tattgtccaa tacctttatc tgaaaaaagg cgaacagaaa gaggattcaa tcaagtaagc
     9241 gagatgttga aagcagcaag aattcctttt cagatgctac tcaaaagaga gaagcatctg
     9301 ctggctcaag caaaaaacac gcgaaaggaa agattggaga tgcctcaacc ttttgaactt
     9361 gcagtcacct tttctaagat acaaaataaa aaaatattga ttattgatga tgtctataca
     9421 acaggacaga ctcttttcca cgcagcagat tgtttgcagg tcgcacagcc gaaaatcatc
     9481 cgaaccattt ctttagcaag atgaattaga tgtggaaatt tgatagcgat ttaatttgca
     9541 aataacctag agttcgatat aatagaatta agaagaggga aagagtggtc cttctccttc
     9601 ttgattgtgg tagacgaaag gggtaatttt tatgtttaga tataatgtac gcggcgaaaa
     9661 tatcgaagta actgaagcga ttcgcgacta cgttgagaaa aaagtaggca aactagaacg
     9721 ctatttcagt gacgcacccg atgcaacggc gcatgtgaac ttaaaagttt atacagaaaa
     9781 aacagcaaaa gtggaagtaa cgatcccatt accttatctt gtattacgtg ccgaagaaac
     9841 ttctccagat ttatacgcaa gtatcgattt ggttgttgac aaattggaac gccaaatccg
     9901 caaattcaaa acaaaaatta atcgtaaatc ccgtgaaacg ggcatgaata ctgcagatgc
     9961 tactgcttta ttcaatgaag aggacgaaaa cgaaaatgat tctgaattag atatcgtacg
    10021 tacgaaacgc ctttcattga aaccaatgga tagtgaagaa gcagtcttac aaatgaacat
    10081 gctgggacat aacttcttta tttttgaaga tgcagaaaca aatggtacaa gtatcgttta
    10141 ccgccgtaaa gatggaaaat acggactgat tgaaacagac tgatcagcct tacttaaata
    10201 acaacgaaaa cttgcagcag ctactgacag ctgccgcaag tttttttgag tttcctcctc
    10261 ttttagatga aatatgaata aattatgaag ttcttacttt aatacgctta agatatttca
    10321 attatctata actaatgata aaatgaaaag taaagtctac atagtctgga taatacacag
    10381 aaggaaaagg agattacaca acgcatggcc aatttgattc gttcacttat cgaaaacgat
    10441 aagaaagaac taaaacgttt agatagcatt gcaaaaaaag ttgaagcata cgctgaccaa
    10501 atggcagcat taactgatga acaattacag gcaaaaactg ctgaattcaa gggcagatac
    10561 caaaaaggag aaacattaga tcaattactt ccggaagctt ttgcagtcgt ccgagaagca
    10621 gcaaaacgtg tattggggtt atatccatac cacgtacaat taatgggtgg gatcgtgctt
    10681 cacgatggga atatccctga aatgcgtact ggtgaaggta aaaccttgac tgcaacgatg
    10741 ccggtgtatc tgaatgcgtt gactggcgaa ggggtccacg tagttaccgt caatgaatat
    10801 ttagcaaccc gtgactcgac ggaaatgggc gagctttata atttcttagg attgacagtt
    10861 gggttgaata tcaactcaaa atcttcggat gaaaaacgcg aggcttataa ttgcgatatc
    10921 acttatagca cgaataatga attaggattt gactatttga gagacaacat ggtcgtttac
    10981 cgtcatcaaa tggtacaacg tccgctgaat tatgccattg tcgatgaagt tgactcgatc
    11041 ttgattgatg aagcgagaac gccgctgatc atttcagggc aagcagaaaa atcaacagct
    11101 ttatatacaa gagcagacaa cttcgtgaaa cgtttgaaag aagaagaaga ttataaaatc
    11161 gatatacaat caaaaacaat cagtttaact gaagcaggga tcgaaaaagc tgaagaaaca
    11221 ttcggtttgg acaacttata tgacattgaa aatactgcat tgacccatca cttggatcaa
    11281 gcattgagag ccaactacat catgctttta gacatcgatt atgttgttca agatggaaaa
    11341 gtattgattg ttgaccaatt tacgggtcgg atcatggatg gacgccgtta ttcagatggt
    11401 cttcatcaag cgatcgaagc taaagaaggc gtagagatcg aagacgaaac gaaaacgatg
    11461 gcgacgatca ctttccagaa ctatttccgt atgtacaaga aacttgcggg gatgactggt
    11521 acagctaaga cagaagaaga agagttcaga gagatttata atattcaagt ataccagatt
    11581 ccgacaaacc gtccggtcat ccgtgacgat cgaccagatt tgctttaccc aacattacaa
    11641 agcaagttcc atgctgtcgt acaagatatc aaagatcgct accgcaaagg acagcctgtc
    11701 ttagtcggaa ctgttgcagt tgaaacatct gagttattat cagatatgct gaatcaagaa
    11761 cgtattcctc atgaagtact gaatgcgaaa aatcacttta aagaagcaga aatcatcatg
    11821 aatgcgggtc aaaaaggtgc agtgacgatt gctaccaaca tggctggtcg gggaacagat
    11881 atcaagctag ggcttggcgt aagagaactt ggtggcctag cagttatcgg gacagaacga
    11941 catgaatctc gtcgtatcga taaccagctt cgaggacgtg caggacgtca aggagaccct
    12001 ggtatgtcac aattctactt gtctttagaa gatgatttga tgaaacgatt cggttcagaa
    12061 cgaatcaaag ctttcttaga tcgaatgaag atcggtgacg aagatgctgt gatccaaagc
    12121 aagatgctga cgaaacaagt agaagctgca caaaaacgcg tagaaggaaa caactacgac
    12181 acacgtaaga acgtcttgca atacgatgac gtgatgcgtg agcaacgtga agtaatctat
    12241 aaacagcgtc aagaagtgat catggaagaa aaaagcttat ctaaaccact gatgaatatg
    12301 gtcaaacgga caatcagtcg tgtggtagat gcgcatacgc aattagaaaa agaaaattgg
    12361 aatttggaaa gtatcgtcga ttttgctggc agcacgcttg tccatgaaga cagtatttcc
    12421 cttacagata tcgaaggaaa aacctctcaa gaaatcaaag aatatctaaa cgaacgagca
    12481 caagaagtat tcaataccaa agcagctcaa ttgaacggac cagagcaact gcttgaattt
    12541 gaaaaagtcg tgatcttacg tgtcgtggac tctaaatgga cagatcatat tgatgcaatg
    12601 gaccaattac gtcagtcaat cggcttgcgt gcctatggtc aaaacaatcc attagtcgaa
    12661 taccaaacag aaggttataa gatgttcgaa gatatggtag gtgccattga atatgaagtc
    12721 actcgtatct tcatgaaagc tgagatccgt caaaacgtac aacgtgagca agtttctcaa
    12781 ggaacagctt ctcactcaga agatggagat gccaaagaaa acagtaatac tagcgcgaaa
    12841 aaacaaccaa tccatgtgaa caaggttggt agaaatgatc cttgtccttg tggaagcggg
    12901 aaaaaatata agaactgtca cggaaaagat gcaaactaat ttctgacagc aggattggtg
    12961 agacaaattc ttttttaaag aatttgtctc accttctttc tgttatttga cgattctgtt
    13021 agactagata taataaaaaa agtatagtga aagaaggaaa aaaacatgga aatatccgaa
    13081 attcgaaatc tcctgacaga aatgcaggaa aaggtcacaa gcttcaggag gtctctttga
    13141 cttagaccag ctggaagaag acattgcgga agcagaagca aaaatggctg aacctggttt
    13201 ttgggatgat agcgaagctg ctcaaaaagt gatcagtgaa aacaatgcaa ataaagaaac
    13261 ttatgatcaa ttccattctc ttgctgaaga actggaagaa atcgaattga tggtggagat
    13321 gttgcaggaa gaacctgatg cagtaatgca agaagaagca gaagcacgta tcaatgcgct
    13381 agatgaaaaa atgaatacgt atgaattatc tatgttgtta gatggtcctt atgatcgaaa
    13441 caacgccatc gtcgaattgc atccaggggc tggcggaacg gagtcccaag actggggcag
    13501 catgctttta cgcatgtata cacgctgggc agagcagcat gggtatcaag tagagacact
    13561 agattatcaa gcaggcgatg aagcaggaat caagagtgtg accctactga tcaaaggaca
    13621 caacgcattt ggctatctga aatcagaaaa aggtgttcat cgccttgtac gtatctcgcc
    13681 ttttgactca gcaaaacgtc gtcatacttc tttttgttcg gtagatgtga tgccagagct
    13741 tgatgaaacg atcgatatag aaatcaatcc agatgatttg aagatcgaca catatcgggc
    13801 gagtggtgca ggtggtcagc acatcaataa gacagaatcc gctgtacgaa tcactcactt
    13861 gcctacagga acagtagtag cgagtcaggc acaacgttca caattgaaaa accgggaaca
    13921 agcgatgggg atgctgaaag ctaagcttta ccaattagaa gtggaaaaga aagaacaaga
    13981 agcagctgca ctgagaggag aacaaaaaga aatcggctgg ggatcacaga tccgttctta
    14041 tgttttccat ccatattcta tggtaaaaga ccatcggaca aacgtagaga caggaaatgt
    14101 ccaagctgtt atggacggag atcttgattt atttattgac ggctatttga aaatgcatct
    14161 gcaataagag ccctttgtta aattgaaata aaattgtaag attttgcaag caagttgaaa
    14221 cattgccatg ctataatagc taaagactga aaaagatatg gagagaacgc catgattgaa
    14281 atgaaggatg taatgaagaa gtactcaaac ggtaccactg ctatccgcaa tctctcgatt
    14341 gtcatcgaac aaggagagtt tgtgtatgtt gttggtccgt ctggagctgg taaatctaca
    14401 ttcatcaaat tgatgtatcg agaagaaaaa gcttcaaaag gaactttgaa cgtcgcaggt
    14461 catgatctaa tagccatcaa aaaccgcgaa gttccttatc tacgcagaga aatcggcgtg
    14521 gtgttccaag actataaatt attaccaaga aaaacagtat atgaaaatgt tgcgtacgcc
    14581 atgcaagtta tcggcagaaa acctcgggat atcaaaaaac gagtaatgga agtgctggat
    14641 cttgttggtt tgaaacacaa agtccgagtc tttcctagcg aattatctgg tggggaacaa
    14701 caacgtgttt ctattgcccg agcaatcgta aatacaccta aagtacttat cgcggatgaa
    14761 ccgacaggga atctagatcc ggaaaactca tgggaaatca tgaaactatt agatcggatc
    14821 aatgcacaag gaacaactgt cgtgatggct acacataaca gtacgatcgt aaatacgatt
    14881 cgacaccgag taattgctat cgaaaacggc cgcattattc gagaccaagc ggaaggggaa
    14941 tatggatacg atgattagaa cctttttccg ccatttatta gaaagtatca agagtttgaa
    15001 acgtaacggc tggatgacag tagcttcggt cagtgcggta acgatcacgt tgactttagt
    15061 tggtgtgttc atggcggtca tcatgaacgc aaccaaacta gcacaagata tagaaggaaa
    15121 cgtggatgta tctgtgttcg tagacattgg tacaaaagac gaagagatga aaaaattaga
    15181 aaaagaatta aatgacttag atcatgtcaa aaaagtcgaa ttttcaagca aagaacagga
    15241 attgaagaaa atccaaaacg aaatgggcga ttcttggaaa ttgtttgaag gggataataa
    15301 cccgttatat gatgtatacg tagtaagtgc taccgatcct tcttatacaa aacaagtagc
    15361 agaaaaagcg gcagatttga agaatgtttc ccgttctgat tacggtgggg cttcctcaga
    15421 tcggattttc caaattgctg gtgcagttcg aacatgggga ttagttgcgg cggcattgct
    15481 gctgtttgta gcaatgtttc tcatttctaa cacgattcgg atcacgattt tatctagaca
    15541 gcgtgaaatt caaatcatgc gtttagtagg ggcaaaaaat ggatatatcc gctggccatt
    15601 tttccttgaa ggtggttgga tcggcttaat cggtgccatt cttccgatac tgatcattac
    15661 atttggttac gcatggtttt accaattgat caatccgtca ttattacgat ctcattattc
    15721 attgatccat ccagaaaata tcgtttggaa aatcaatctt ttgatggtcg gtattggtgt
    15781 gatcattggt tcactcggct cgatcatctc tatgagacgt ttcttgaaat tctagtgtca
    15841 caagataaat ataatcagaa agttggacga tttcgttcca gctttctttt tttatcagct
    15901 aggtggagta aatggggcgg cttttttctc tttactttaa aaaacaactt gggtattctt
    15961 aagttggtag aaaaagaggt gaagccgtga agattatcgt tgacaatttt tttacgatcc
    16021 ttttgattat gaatattttg ctttccttta ttatcgtttt tcgagaaaga aaggaaactg
    16081 cgcaaacatg ggcatggctg ctcgttttga tgttcattcc agttgtagga tttattttat
    16141 atattttttt aggaagaggg atttccaaag agaaaatctt tgatttgaag atccaaggga
    16201 aaatcggtaa gaatctagaa atcgaagaag ataaacaagc attgatgcga gggctttatc
    16261 ctcatccgcc tactggacaa gtagatgtga aacaattgat ctatatgctt actgtatttg
    16321 aaagtacgct ttatacgact aaaaatgaaa tcactttatt tacagatggt cgtgaaaaat
    16381 tcgatgcgct gatcgaggat atcaaacagg cagaagacca tatccatttc caatattata
    16441 tttaccgcag tgatacatta ggtgaagaag ttcgagaggc attgacagag gcagcaagac
    16501 gcggagtaaa agtcagagtc cttcttgatg catggggttc cacacaagtt tcttctagtt
    16561 tttttcagaa tttgaaaaaa gcaggtggag aagtcgcatt tttctttcct ctattcgttc
    16621 cgtatatcaa tcctcgaatc aattatcgca atcatcgtaa aatcgtagtg attgatggga
    16681 aaatcggata tacaggtggg ttcaatgttg gaaacgaata tctaggattg gtaaagaaat
    16741 ttggttattg gcgagacaat catctgcgta tctatggaga agcggtttac accttgcaaa
    16801 accgtttttt gatggactgg aattctcagc atacaaaaga agtaggatat tcaccggaat
    16861 ttttcccgac cattcattct acaggtgata tggctgttca aatcgtgaca agcggaccag
    16921 ataccgaaca tgagcaaatc aaaatgacat atttgaaaat gatttcgtta gccaaacggg
    16981 agatattgat ccaaacgccg tattacatac cggatggatc gattcatgag gcattgaagt
    17041 tggctcttct ctcaggcgta aaagtccata tccaaatacc taacaaacca gatcatcttc
    17101 tcgtttactg ggcaacgtat tctttcgctg cagagctgat cgagtatggg gcaagaatcg
    17161 aaacatatga aaatggattt atccatgcaa agacgatgat tatcgatggc ggcatcgttt
    17221 ccgttggttc agctaatatc gacgttcgct catttagatt ggattttgaa gtcaatacac
    17281 tgatctatga tgaacgaatg gcttctcgcg taagaaaagc attctttgaa gattcaaaga
    17341 tttcgacgca tctcacaaaa gaagtgtatg aaaaccgagg gatgatgatc aagatgaaag
    17401 aaggattagc aagactgatt tcgccgctcc tttaaaatac aaaaaggaca ggagagccat
    17461 caatagatgg aaatctcgcg tccttttttc tcggggccat ttctgagagt acgtcagaaa
    17521 tggagaaagc gtctcgcatg agcgaaatta actttggggt atctcttgtt ttttggggaa
    17581 agcaagaaat aagctaatat atgctattaa aagagacaca tttcaaagcc agtatagcat
    17641 agaaactttt aatgagatag ctttttttgc aattatgaga atttattttg ttatttaatg
    17701 attttgattc gttttcatca agtaatgaaa atgatagaat aaacatactt taggattaaa
    17761 ggagatttct aatgaaaaaa ctaaaattat tcttaccaat aataggatta gctattcttt
    17821 tatcaggctg ttcaaagtgg attgatcgag gagaatccat tactgcagtt ggctcttctg
    17881 ccttacagcc tttagtagaa acggttgctg aaacctacca ggcagaaaat cctggaaaat
    17941 tcatcaatgt acaagggggc ggaagcggaa ctgggttgtc tcaagtacag tcaggagcag
    18001 tcgatatcgg aaattctgat ttgttcgcgg aagaaaaatc agggattgat gcttcggcat
    18061 tagtcgatca tcgagtagca gttgttggaa tcactcctat tgtgaacaag gatattggcg
    18121 taaaagatat cagtatggaa aacctgaaaa aattatttac gggcgagatc aaaaactgga
    18181 gtgaagtcgg tgggaaagat cagccagtag ttatattgaa ccgtgcatca ggaagcggga
    18241 cccgtagtac gtttgaaaaa tgggtattgg acggagaaac agctgttcag gcacaagaac
    18301 aagattcaag cggaatggtg cgccaaatcg ttgcggacac acccggagca atcagctatg
    18361 ttgctttttc ttacgtttcc gatgatgtgg atacgttgaa cgttaacggt gtggaaccaa
    18421 cagatgaaaa tgtgacaacg aacaaatgga cgatttgggc atatgagcat atgtacacaa
    18481 gagaccatcc aaaaaaactg acaaaagaat ttttagacta tatcttatct gatgaagtac
    18541 aagataatat tgtcggagag ctaggctata tccctgtttc acatatgaaa gttgaacgtg
    18601 attggcaagg aaacattgtt aaagagtaat ctttacacaa aatttacaaa cttagctaaa
    18661 cttttacatg ttattaaaac caaattgatg ttcaatttgt acactgagtg agtatgttaa
    18721 acctgattaa gggggagtca tctgtggaag atgtgaaaaa agtattatta acaaaatcaa
    18781 aacgttcaaa aatggaacag cgcggaaaat tcattagttt tttgtgtatc gcgctgatcg
    18841 tgttggttgt attatctatt ttttattttg tcgctagtaa aggattggcc acctttttta
    18901 ctgataagat caatgtattt gattttctgt ttggtacaga ttggaatcca agccaaatag
    18961 gagcaaatgg gaaacccatg gtaggggcat tgcctatgat cacaggttca tttattgtga
    19021 cctttttatc tgctattgtt gccacaccat ttgctattgg agcagcagtg ttcatgacgg
    19081 agatttctcc taaaaacgga acgaagatct tgcaaccggt catcgagcta cttgtaggta
    19141 ttccgtctgt cgtttacgga tttatcggtt tatctgttat cgtgcctttt gtcagaagta
    19201 tctttggcgg gacagggttc ggtatcttag ctggtacatt tgtgttattc gttatgatct
    19261 taccgactgt cacaacgatg actgtggatg cattaaaggc agtgccgcga cactatcggg
    19321 aagcttcatt agcgctaggt gccacaagat ggcaaacaat ctacaaagtg gtgctgcgag
    19381 cagcagtgcc cggaatttta acagcagtcg tttttggtat ggctcgtgcg tttggcgaag
    19441 ccttagctat ccaaatggtt attggtaatg cggcattaat gccaacagga cttactactc
    19501 ctgcttctac attgacgtcc atcttgacaa tgggaatcgg aaatacaatc atgggaacag
    19561 ttgaaaataa tgtgttatgg tcattagcgc tgatcttgct attgatgtca ttattcttta
    19621 atatcgtgat ccgtatgatt gggaagaaag gagagctgaa ataatgaacg caaaacgctc
    19681 agataaaatt gctacaggtg ttctatatgt ggtttcaggg atcatcgtat tgatcttagc
    19741 agctttatta ctttatatct tagttcgagg aataccgcac atttcatggt cattcttgac
    19801 tgaaccttcc aaagcctacc aagaaggcgg tgggatcggg attcaattat ttaactcgat
    19861 ttatttgctt ttgattacca tgatcatcag ttttcctatc tctttaggtg cgggtatcta
    19921 cctttcggaa tatgccggaa aaaactggct gacagacgtg atccgtacgt ctatcgaaat
    19981 cttgagctct ttgccttctg ttgttgtcgg tttattcggt ttcttggttt tcgttattca
    20041 attccagtat ggtttctcaa tcatttctgg tgcattagct ttgaccgtat tcaacttgcc
    20101 tcttttgact cgaacggtcg aggaatcttt acaagcggtc cattacacac aacgagaagc
    20161 tggattggcg ttaggtttgt cacgctggga aacagtgata aaagtggttg ttccagaagc
    20221 gacaccagga attttgactg gtgtgatcct aagttcagga agaatttttg gtgaagctgc
    20281 cgcattgatt tatacagctg gtcaaagcgc gccagcatta gattttacga actggaatcc
    20341 attaagtgtt tctagtccga tcagcatttt ccgccaagct gaaacactgg ctgtccatat
    20401 ttggaaaatc aacacagaag gtacgatgcc tgatggtgtt tctgtttcgg ctggcgcttc
    20461 tgccgtgttg atcattgctg ttttactgtt caacttcggc gctcgtgcga ttggcaaacg
    20521 attataccga aaaatgactt cagcctaagg agaagaagta aaatgaaaaa atataattgg
    20581 aatgaaacaa atgtcattac catgccaaaa gataaggaag ttgcattata tacgaatgat
    20641 ctgcatgttt ggtatggcga caatgaagca atcaagggag tggatctaga attcgaaaaa
    20701 aataagatca ctgcattgat tggtccctct ggctgcggaa aatccacgta tcttcgttct
    20761 ttgaatcgta tgaatgatgg gattgctaat acgaaaatta ctggaaagat tatgtataaa
    20821 gacgtggata tcaatgcgcc tcaagtggat gtttatgaaa tgcgtaaacg gatcggcatg
    20881 gtgttccaac gccccaaccc ttttagcaaa tcgatttatg acaatataac ttttgctttg
    20941 aaacagcatg gtgaaaaaaa caaaaagaaa ttagatgaaa tcgttgaaac aagcttgaaa
    21001 caagcagctt tgtgggatca agtaaaagat agcttggata aaagtgcctt ggctttatct
    21061 ggcggacaac agcaacgttt gtgtatcgct cgtgcaatcg cgatgaaacc cgatatcttg
    21121 ctgttagacg agccggcaag tgccttggat cctatttcga caggaacggt tgaagaaaca
    21181 cttgtaaact tgaaagaaga ctacacgatc attatcgtga cgcataatat gcaacaagca
    21241 gctcgtatca gcgactatac tgcctttttc tatctaggaa aagtaatgga atatgacaaa
    21301 acaaacaaga tatttaccag accaaaaatt caggcaaccg aagattatgt gtccggtcat
    21361 tttggttaag acggaggcct caacatgaca aaagaaatta tctcatccaa agatcttcat
    21421 ctgtattatg gaaagaaaga agcactaaag ggaattgatc taagtttcaa tcaaggtgaa
    21481 atcacagcga tgatcggtcc ttctggttgc gggaaatcta cctatctacg ttcgttgaat
    21541 cgaatgaacg atctgattcc aaatgtaacg atcaccggaa gtgttttata taaagacaaa
    21601 gacatctatg gtccgaaaac agatgttgtt gaactaagaa aagaaatcgg catggtgttc
    21661 caacagccaa atccatttcc tttttctatt tatgaaaatg tcatctatgg attgaagtta
    21721 aaaggtgaaa aagataaaaa agtccttgat caagtagtgg aagaaagtct gaaggcagcg
    21781 tccgtttggg aggatgtgaa agataaactg cataaaagtg ccttgtcttt atccggtggg
    21841 cagcagcagc gtgtatgtat cgcacgtgtt ttggcagtga atcccgaaat catcttattg
    21901 gacgaaccaa caagtgcact tgaccctgtt tctactggga aaatcgaaag tatgctgtta
    21961 gaattaagag agcggtatac gatgatcatc gtgacccata atatgtctca agcttcacgt
    22021 atttcagata agacggcatt ctttttagat ggtcacttga tcgaatacaa cgatacgaag
    22081 aagatattca tgaatccaga aaaacaagag acagaagatt atatttcagg tcgatttgga
    22141 taaggaggaa acggaatgct acgtacacaa tttgaagaag aattgctgaa tctccataat
    22201 cagttctacg aaatggggat gatggtgagc agcgctgtgc acaagtcagt tcgtgcatac
    22261 atcaaacacg ataaaatctt agctcaagaa gttatcgaaa acgatataaa tatcaataat
    22321 atggaaacgc gtttggagaa gaaaagtttt gaaatgattg cattacaaca gccagttaca
    22381 actgacttgc gtatgattat cacggtcatg aaagctagct ctgatttaga acgtatggcc
    22441 gatcatgcgg tgtccgttgc taaatccaca atccgcgtaa aaggacagac gagaataccg
    22501 gaaatcgaaa aagagatctc cgatatgtcc gattacgtga aaaaaatggt ggacaacgtc
    22561 ctagttgcgt atgtcaaaac agacgaaaaa gatgcgcgta caatcgccaa tatggatcaa
    22621 agagtcaatg actatttcaa tcgaatctat aatgcaacca tcaaaaacat gcaagaaaat
    22681 cctgaaacag tcatcagtgg cacagactat ttgaatgttg ccagctatct agaacgaatc
    22741 ggagactatg tgacaaacat ctgtgaatgg atcgtctact tggctacagg gaaaatcact
    22801 gaattaaata cgaaccacaa tgagattttc taaactgaag ttgtgattct gctgtttatt
    22861 taggaaaaga ggttgtgaaa tcagcgtttt gtcctgagta ttagagaaac aaacggtaaa
    22921 atagttcctc atattttgcc gttttttgag ctaataccga aggtcagctg attgaacacc
    22981 gtttattctg gaaaagggtt tgtgacaaaa catgtcacaa acccttttca ttattccaat
    23041 agaaaggata aagaatgcaa aaaaagatta gcatcatcat cactctattt tttatttgta
    23101 tacttgcttc atggtttatt cagcgtcaag ctgctctata tgacgtacct gtcatcgaga
    23161 tcgaaagagt gagaatagaa gaggatcaac aattgattac aggaagattg atgaatacgg
    23221 accaaaaagg agaagtgatt tctttaacgg ctccttatca aaaaaatcaa atcgaaacag
    23281 caaatataac aacaagacaa atctatcttg tccaaatgca tggagatgaa tggcaactag
    23341 tagcaaaaaa aaatgatggc tggctttttt tctttacaag tgtcttcatt ggcaccatgt
    23401 tgcttattgg tggaaaacag ggcgtatttg ctttaggaag tctcatcatc aacatcgttt
    23461 tacttttact tttgttgctc ctctttacca aaacagaagg tatttctctc ttaaatatag
    23521 caatcttatt tgtcgttata gggataatcg ttagtatatt ggcgttagac ggatggaata
    23581 gaagcagtat aatcaaaatt tcggctgcag ttacaagtgt ttttttagca ttttttattt
    23641 gtcttttgac aatgaatcat tggaaagatc aaggactgcg ctatgaagaa ctgaattatc
    23701 tgacacgacc gtatcgttct gtttttcttt ccagcgtgct gattgggaca gctggaggga
    23761 cactcgatac cgtgatcaca gtcattgcga cattagaaga attgaccaag caacaaccga
    23821 aaatatcagc gaaacagtta tggctttcag gaaggcaagt gggccgagat gtgattggtt
    23881 cgatggctaa tatcctttta ttcgtctata tcagcggagc gattccatcg cttctgttat
    23941 atttaggaaa tcaatggtct ttcaaagaaa cggtagaacg acatttatca ttagaacttt
    24001 tacgcgtcat tgctggcagc ttaggaatag tattatcaat ccccatcgcg gtcctctttt
    24061 ttctcgctgt aaggaggtta aaaaaatgaa tgtacttatt atacttgttg ggatttttgc
    24121 aatcagtgtg ctatttgtcg gtggtacgca aggtatgtat attcttttag gattattcat
    24181 taatttagga atctttttcc tattattatt cggctatcat cagaagtggc cgatattggt
    24241 attgtcgatt atagggttcc tattgatcgc tgtggttatc ttatttttta tcaatggtta
    24301 taatctgaaa atgcgagccg cttttgccag tatactgatc tttttgtttt gtttcctact
    24361 attgattcct atcactgatt ttttagcgat ccaaggcttt acttcgatag aactagaaga
    24421 actatctggc ttagataaga cgttagcaat tgattttaga ctacttacga ggtcgttgct
    24481 tctgatcagt cttagcggag ctgttttaga tgcgagtgta gcgatttcta gtggaacatt
    24541 cgaagtatat caggcaaatc cgcaaatgtc ttttaaccaa ttgcgccatg ctagctttgc
    24601 cattgctaaa aaaatattgg catcaacagt gatgacgctt ctttttgcgt ttatggggag
    24661 ttctttagcg ttgattcttt ggtttattga cttagacatt tcttttcagc aaataatcaa
    24721 tgaaaaatca tttgtcttgg aatatacgat ggctattctt accacactgg ccgcactact
    24781 tgtcctgccc ttaacttgcg tgactacagc atatctcttt acaaaaaaga aagaacatct
    24841 caagatggag taaaagttac aacttaagtc ctatgacatt tttactgaat cagtgcataa
    24901 tatggatgta aggaaaagct tgcaaacaat tttgcttaag gaggcaattt ccatgaaaga
    24961 aagagaacgt attttagact tagtgaaaaa aggaatcctt tcgactgaag aaggcttaga
    25021 tttattagaa agcatggcaa ctgaaaaaga cgaaaaacaa atcaaaaaag aagcagacaa
    25081 ggtaactgct agtcataaag aaaaagatca ggcaagtcaa ttgatcgatg aacttgaaaa
    25141 cggtgaagaa aaaatttctg agccagttga tccaaaagaa aaagaaagac aagatcaaga
    25201 aaacttagaa aagatcttag atgaactagc aactgaagcg aataaaactt cggcgcgtct
    25261 agacgaagta aatgctcaat tcgctgacaa taaggcagca cgtaatgaga aacaggaagc
    25321 attgatgcag ctgaatacaa aagaagaatt aggcgagttg acagaagaag aattagcaca
    25381 gcgtcaaacg ttagaagcag aaatcaaaga gttagaagca accggcgata cactattaga
    25441 agaacaattg aagctggaag cagaattaaa agatatccgc aagaatcaat ggtctgagaa
    25501 aaaagaaaca tttacggata agtttgaatt gccagatgat tggaaagatc aagcgacaga
    25561 tacgctgaat caagtaggcg aaaaaatgtc agaagctgga tcacagttag gcaaattctt
    25621 gaagaaaaca ttccaaactg tttcagaaac agtaaatgat aacatggaat ggaaagatgt
    25681 cagcttacgc gtccctggaa ttgcgacaac gaaatttgaa cacgaatttt attatgaagc
    25741 tcctgcagca agtatccttg atatcaaggc agcaaacgga aacgtgacgt taaaaacgtg
    25801 ggacagtgat gatgtgaaag tggaagccaa gatcaaactt tacggaaaaa tgggtgctga
    25861 accatttgaa gcattctctg aacggagcca gatcgaggtc aatgaagatc atatctcctt
    25921 ccaaattcca aataagcgtg tgcgtgcaga ccttgttttc tacttgccta aacgagtata
    25981 cgaccatgca gctatcaaac ttctaaatgg caacatcatg attgagacat tggaagctaa
    26041 agatatttat acaaaatcta cgaatgggaa catcatcgtg aaccaattaa ctgcaacgat
    26101 gctggaagta gaaggtgtaa acggcaatat cgatattcga aacgggaaca tcttagattc
    26161 tattatagaa acagtaaacg gtacagtgac atttggtgcc acaccagaaa acctttctgt
    26221 gtctttagta aatggtgatg tacgtcttac gattaaagaa gataatttga aaaaagtaga
    26281 agcaagttca gtgaacggga atgtcaaagt tgctttacca gatagcatcg gtttggaagg
    26341 acacgctaaa acaagtcttg gaagcattaa cagccgtctg tccaattacg aagtagttcg
    26401 tgagaaaaaa gaacggacaa accaaatgtt gcaattccgt cgtgtttcag atgatgagat
    26461 cgcacaagtg cagctttcaa cgacaacagg aagtatctat ttaaaagata cagataaata
    26521 aagaggttgt gaaagagatg ttcagccttg agcaataaga agcgattttt taaaatagct
    26581 tcccctattt taaaaaaatg tgccttattg ccgataggct atctcttgaa caccgattaa
    26641 gaagaaggtt gtcacaacga ttttcttcat ttaaaatagt agaacagagg tgagacatga
    26701 tgaaaaaaaa gttgacaaaa tccaataaaa atgttgtttt gacaggtact ttagcaggga
    26761 ttggggaata tatcgggatt gatcccactg ttatccgtgt gctttatgta ttcttaagct
    26821 tagttgcttt tggaagtcca atcattttat acattttatt agctttgatt atcccatctg
    26881 cgcgttctgc acgaacaaac tatggacata acaatgcata ttatgaaaaa aacaattatc
    26941 gtgaacaaac aaaaaaacgc aaagaagcgg aaaaaatcga tgatgacgaa tggagtgact
    27001 tttaatgtcg tactttcagc gtattttggt taatacgtta acattcatat cgttggctgt
    27061 tctttttcct gcgatggtcc atgtgagcag tatttggacg gccgtccttg ccagcttcgt
    27121 attatctgtg ttgaacatgt ttgtcaaacc gattttgacg atcctgtccc tgccctttac
    27181 attagtcaca ttgggattgt ttacgtttgt tatcaatgca gcgattctta aaatgacttc
    27241 cttttttgta ggagcagaac attttagttt ttcttcattt ggtgcagcgt tattcgtagc
    27301 tatcttgatg tcacttgtca atgtaattgt tagtgaacat aacagcagaa aataaaaaaa
    27361 gctgtgccga gatctcggcg cagctttttt gtttagaata aagaatgcgt tttctattac
    27421 attggtaatt aaataaaaac gtttttttta attggtagta cttttggcta gacaatgata
    27481 aaatgataga gaacactcta atagaaatga ggtagcatga atgtcagaag ttgtaaaagt
    27541 tagccaatta gtaaaaaaat tatctttgga aatcgtcaca ggcgacgaga aaagtttaga
    27601 ccgcgtcatc gtgactgggg acatctcacg cccaggacta gagttgaccg gttattttaa
    27661 ttattattcc cataatcgtt tacagctatt tggcagtaaa gaaatcagtt ttgcggaacg
    27721 gatgatccca gaagagcgtt tgatcattat gagaagatta tgtagtgaag atatgcccgc
    27781 atttattatt tcaagaggat tgccggctcc ggaagaaatg atccaagcag ccaatgaaaa
    27841 tgggatagct gtgctgcgtt cgcctatctc aacgtcccgg ctgctaggtg aattatctag
    27901 ttatttagat ggacgcttag cccctcgaac aagtgtccac ggtgtgttag tcgatgtcta
    27961 cggattaggt gtactaattc aaggggacag tgggataggg aaaagtgaaa cggcgttgga
    28021 actgattaag cgcggacatc gattgatcgc agacgatcga gtagatgtct atcagcaaga
    28081 tgaactgacg gtaatcggag aacctcctaa aatcctggaa catctgattg agattcgagg
    28141 gatcggtatc atagatgtaa tgaatctttt cggtgcgagt gcggtacgag gctctatgca
    28201 agtccagtta gctgtttatc tagaagcatg ggcgaaagat aagaaatacg accgtctggg
    28261 ctctgaagac acgaccgttg aaatcgcgga agtgggcatt ccacaaataa aaatccctgt
    28321 caaaacagga cgaaacgttg caatcatcat tgaagtagcc gcaatgaatt tccgcgcacg
    28381 tacaatgggc tttgacgcaa cgaaaacatt tgaagaaaga ttaagtcgct tgattgaaga
    28441 aaactcaggc aatgactagc aaggagtgac aatatgttag cacaaatcaa tcgagttgct
    28501 tttgagcttg taggaattcc tatctactgg tatgcattga ttatcgtatc aggaatcatt
    28561 attgccatgt ggctcagcag cagagaagct gttcgggtag gattaaaagc agatgacgtg
    28621 acagatttta tgttgtgggg attgccgatt tccattattg gtgcccgctt gtattatgtt
    28681 ttattcgatc ttccccaata tatagctgat ccaatccaga tattcaatat ccgttcagga
    28741 ggattagcga tttacggggg attgattgca ggtgcaatca cactgtactt ttttaccaaa
    28801 tatcatttta tttctttgtg gaccttttta gatatcgctg caccaagcgt attattggcg
    28861 caggcaatcg gacgatgggg aaatttcatg aaccacgaag cgtatggtcc agacacgaca
    28921 cgaagtttct tagaaagtct gcatttaccg caattcatca ttgataacat gtatatcgaa
    28981 ggaatctatc gacaaccaac ctttctttat gaatcacttt ggagtttgat tggatttatt
    29041 ctgcttttgg ttttgcggaa gaaaccacat cttttgaaaa aaggagaagt ccttttatgt
    29101 tatctaatgt ggtatagttt cggacgtttc tttatcgaag ggttacgcac agacagcctt
    29161 tactttttag gtgtgatccg catttctcaa ttattgtctg ctgttttatt tgtcggcaca
    29221 ttgattctgt ttatttggcg tagaaaaaaa ggaagtttac cggattatga ccgctcatta
    29281 ggaaaaaatc aacaaattat ttgattttca gagcgttaaa aatgaaaaaa atttcaggag
    29341 tggtaaaatg aattatagag tagcggtttt aggaccaggc tcttggggga ctgctttagc
    29401 acaagtcctc gctgaaaacg gacatgacgt tcggatttgg ggacatcgtg cttcacaagt
    29461 agaagaaatc aacacccaac acaccaatca acgttattta ccagatcatc atctacccga
    29521 ttccatccga gcattcaccg atatggaaga tgcagtaaaa gatgcagatg cggtactatt
    29581 cgttatcccg acgaaagcga tacgttctgt tgcaaaagaa ctagttgcca aattgaatac
    29641 gaagccagtg atcatccacg caagtaaggg attagaacag ggaacgcata aaagaatctc
    29701 tgaaatcttg ttagaggaaa tcccgacaga aaaaagaaaa gctgttgctg ttctttctgg
    29761 gccaagccat gcggaagaag tagcaaagca tgacattacg acgatcacag cggcaagcac
    29821 aaatgtaaaa gcagcaaaat atgtacaaga gctgttcatg aaccattatt ttcgaatcta
    29881 taccaaccct gatgtgattg gtgtagagat gggagcagct ttgaaaaata ttattgccat
    29941 tggagctggt gctattcacg gcttagggtt tggcgataat gcaaaagcgg caatcatgac
    30001 gcgcggatta gctgagatca gccgtttagg tgtagcaatg ggtgccaacc cgctgacctt
    30061 tattggctta agcggagtag gtgatctagt cgttacttgc acaagtgttc attccagaaa
    30121 ctggcgcgca ggcaacttgt taggacaagg tcagcctcta gaagaggtgc tagccaatat
    30181 gggaatggtt gttgaaggtg tgaatactac tcaagcagcg atggaactag cccaaatgat
    30241 ggaaatcgaa atgcccatca ctcaaacaat ctatgaagtg ctgtatgaac aaaaagaaat
    30301 caaaacagcc gcaaaagaaa tcatgttacg tgatgggaaa aaagaaaatg aattctcatt
    30361 aacaattttt tgaaggagcg aatgtatatg aaagtaaaaa aagcagttat tccagcagca
    30421 ggattaggaa caagattttt accagcaaca aaggcgatgg caaaggaaat gttgccaatc
    30481 gtggacaaac caacgatcca attcatcgtt gaagaagcgt tgaaatcagg aatcgaagac
    30541 atcttgatcg ttacaggaaa agctaaacga ccaatcgaag atcactttga ttcaaatatc
    30601 gaattagaaa caaacctaag tgaaaaagga aaaaccgaat tattgaaatt agtagaagaa
    30661 acgacagatg tcaatttgca tttcatccgt caatctcatc caaaggggtt aggacacgcc
    30721 gttcttcaag caagagcctt tattggaaat gaaccgtttg tcgttatgct aggcgatgat
    30781 atcatggaag acgaagtacc attgacacag caattgatcg atgactatga gcgtacacac
    30841 gcttctacga ttgccgttat gcaagttcct cacgatgaaa cttcaaaata cggaatcatc
    30901 aacccagggg aagtactgga agatgggtta tacaatgtca aaaactttgt tgaaaaacca
    30961 gatccaagca aagcaccaag tgatttagct attattgggc gttacttatt gactccagaa
    31021 atctttgatg tattatcaga acaacaacca ggcgctggaa atgagatcca actaactgac
    31081 gcaatcgata cgttgaataa aacacaacgc gtatttgccc gtaaattcac aggtaaacgt
    31141 tatgacgttg gtgacaaatt tggttttatg aaaacaagta ttgaatatgg tctgacacat
    31201 ccagaagtag gggcaccttt gcgtgaatac atcatgtctt taggtaaaac attagaagca
    31261 gaaggaagca agatcaatca taatccaaaa ggaataacag aaatcaaaga agaaaagaaa
    31321 aaataatctt tttttctaac gagcttcagc tgctaattga ataaaaagta gttgaagctc
    31381 gtttttattt gtttaaaaaa cacgaaaatg ctatccttat agaaaagaga gacaagaagg
    31441 gagtttgatc atgtcaggag gagaaattgc aggattgatc gcagcaatcg cctttgcgat
    31501 acttgtcgtt ttcatcgttc gcgtattgtt gcaagtttcc aaaactttag aaaaagtaga
    31561 ccagactgtc gcagaagcaa atacgacaat tgagatcgtc acacaagacg tagatctttt
    31621 atctagacaa gtagaaggct tgctagtcaa aagtaatgag ctgctcttgg atatcaatgg
    31681 aaaagtcgca acgatcgatc cattgttcac agcagttgct gatttaagtg aaagtgtatc
    31741 ggaacttaat cattctagta aaaacatcgt gacgaaagtc ggcggaatcg gaaaaacgac
    31801 agctaaagcg actgttgccg gaaaagtcgg tggaacagcg atgaaatttt taaaaacaaa
    31861 aaacatactg aaacgacagg aggaaaataa gaatggctaa aaaaggtgga tttttattag
    31921 gtgcagtagt tggaggtaca gccgcagcaa tcgccgcatt attgttagca cccaaatctg
    31981 gtaaagaact tcgggatgaa ttggctgctc aagcagatga tttgatggac atggcttcag
    32041 attacacaga tatggcaaaa gaaaaatcat ctgagttaac aggtattgca aaagaaaaag
    32101 cgcaagatct ttctcaacaa gcaggggatc tagcaggcaa tgttaagcag aaggtaagtg
    32161 aatcagcaga ggaagcagga agcgaatcag atgatatctt gttaaacctc aaagaacaat
    32221 cagctgattt atctaatcgt ttcaaaaaaa cagcagaaga tctgaaaaag ccagcagacg
    32281 aattaggtag tattgctaaa gatacttcag aagatatcat gatcgatgta aaagatgctg
    32341 cagataaagc aggagagacg gtcaatgaag gaatgtcaga agcaaaacca gttgcagatg
    32401 acacaaaaga aatgttgaaa atggcaaaag aagatgcaaa agaagatgca aaagaagcta
    32461 aaaaagaaat gaaagataca atgacagatt cgactaccaa tcactaagat tactcatttc
    32521 tagaataaaa aaggtgagag cggaccagct ctcacctttt ttattttcat tactctaaaa
    32581 caagtaattc ttttggtgta gtcgtgaatg gcacacaacc atcacttgtc acatacacac
    32641 aatcttcgat acgtacccct actttttcag gaatatagat tcctggttca agagagaagc
    32701 acatcccttc ttcaatcact aagtcgtttc cttctacaag agaagggaat tcgtggacgg
    32761 ttgttccgat tccgtgacct aaacggtgat tgaaatattc gccgtagcca tagctgttga
    32821 tcacgtttcg tgcgatttga tcaagttcac ctgctgtcac acctgggcga actgcctctt
    32881 gtgcggcaag ctgtgcttca agagtgatgt tatagatttt ttcttggaat tcagttggtt
    32941 tttgataagc aactgtacga gtagcatcac tgcaatagcc attccaaata acgccaagat
    33001 cgaataacac tagttcattt ggtgaaacct tcgtgcttcc tggtgtacca tgagggcttg
    33061 cagcatttgc tcctgcaagg actaatgtgt cgaaagacat ttgtgaaaca ccttgttttt
    33121 ttaattggta ttcgatttct gcgataattg cttgttcagt tacgccttct tttactgttt
    33181 tgaagccaat ttcaaaggca acatcggccc atttaccagc ttcgatcagt ttgtcttttt
    33241 cttctaccgt tttgatcagt tgcagacgct ggataataga agttagatcg gtgtaagaat
    33301 ctgtacctgt caagatatca gagatagcat cgaagcgatc gacagtcaga gcattctttt
    33361 caatacctac attaccaggt tgcccatagc gtgcgcgaag ctcttttccg atgatctccc
    33421 aaggattttc gctgtctaag tagccacgta catcgtacgc ccagctgctg ttttgagcat
    33481 cttcaacttc cagagcagga gtgaaaagga aaggatcttg ttccagaggg ataaaaagag
    33541 ctagtacacg ctcgtgagga tcactttcat atccggaaaa gtaagcgatg tggccagggt
    33601 cgctgatata agccaattct aattggtgtt gtgccatcca ttgacgtagt tcattgattt
    33661 ttacgttatt catttggcaa cctactttct aaattaattt tgtattcaat aattgtacca
    33721 ctgattgatt aaaagaccaa cgttcttaaa actgaaaaaa gtaaaaattt tcatgaaaac
    33781 agagataaaa cggttgcaat tgttgagatt atttgatatc ctattttaga aatgtaagac
    33841 gtattttcag aaaacatata aaatatgaat aggagaacac aaatggaaaa gcaaacaatc
    33901 actatctatg atgtagcgag agaggcaaat gtttcgatgg ctactgtttc acgtgtcgta
    33961 aatggcaatc caaacgtcaa accagcaaca agaaaaaaag tcttggaagt tatcgatcgc
    34021 ttggattatc gtccaaatgc agtcgcacgt ggcttggcaa gtaagaaaac aacaacagtt
    34081 ggggtaatca ttcctgatgt cagcaatatg ttctttgcct ctttagcacg tggtatcgac
    34141 gatgtggcaa caatgtacaa atacaatatc atcttagcaa actcagatgg caacgatcaa
    34201 aaagaagtca atgtattgaa taatttattg gctaagcaag tggacggcgt gatctttatg
    34261 ggtcaccata tcacagacga aatccgtgga gaattttcac gttcaaaaac gcctgttgta
    34321 ctagctggtt ccattgatcc agatgaacaa gtaggtagcg taaacattga ttatgtatca
    34381 gcaacaaaag atgcagtaaa taaattagca aaaagcggca ataaaaaaat cgcttttgtc
    34441 agcggtgcgc tgattgatcc tatcaatggt caaaaccgtc taaaaggcta taaagaagca
    34501 ttaagcgaaa acaatctacc atatagcgaa ggattgattt ttgaggcaca atacaacttt
    34561 aaagatggtc tgtctctagt tgaccggatc cataatagcg gtgcaacagc tgtctatgtt
    34621 tcagacgatg aattagccat tggtatcttg gatggtttat tagaccgcgg cgtaaaagta
    34681 ccagaagaat tcgaaatcat cacaagcaac aattctttac tgacagaagt agctcgtcct
    34741 cgtttgacaa gtatcacaca accattatac gatttaggag cggtatccat gcgcctattg
    34801 acgaaaatga tgaataaaga agaagtcgaa gaaaaaacga ttatcttgcc ttatggaatc
    34861 gaagaaaaag gatcaactaa ataataaaag atcaatcatt taaaggttgt tcccaaagtg
    34921 gtcaacttct ggaacaacct ttatacgaga aaaggggtta tgacaaaatt ttgtcataac
    34981 cccttttttt gtgactttaa aaaaaagaga gaatggcgga aacaaacctt acgtccatcg
    35041 tatacgacac aatctgtgcg tagatgctac attttgttca ctactatcaa aattacttta
    35101 aaatgaaaac gtgataaaaa agaaagtaga aaagtagaaa agtaactcta aaaaatccaa
    35161 aaaaatccag gctcgattgc gtacttatct taaaggagaa acaatccatc atacataacc
    35221 cgaaaggaga cttctatttg cctaagaaaa gacgaaagac catagtcatc attttgacca
    35281 ttcttactat aggaatcgga ggaaaatttt acatggacaa aagagaagcg caaaaacagc
    35341 aagatttact cgcagtagaa aaacagtccg tcaaagttct gaaaaatacc tttgcggata
    35401 tcaaagaagt gaaaatcgaa caatttgaga aaaacgacat gacaggaatc tatgaagcat
    35461 tgataacgat gaccaataca gaaggaaaag ccgtttattt tgattatagc tttacaaaag
    35521 aaagcaatga gatagatggc tatggtgttg aaaatgaaga agtacaaaaa gaagggatta
    35581 cggttgatga gattatagtt atctatacag atgggagtga ggaaaaagta tgacaattac
    35641 tgataagcag tataaaggaa taagtaataa agtatattgg ctagatccaa aacatcctca
    35701 atatagtaaa agttacaaag aaggcgccat taaaaacttt ggagaaacaa aattccaaat
    35761 cctaaaaatc aaaaactcct tcgacggcat gcaggcgatg gctgtagcgc caatcaagaa
    35821 cggtaaagtg gatatttctc aagtagtgat tgcttttgca ggaacgaact taagcgattg
    35881 gaaagatttg gaaacggatg caagaagtgt tatgaatctc tatgggaata gaccaggagc
    35941 aagtttttct gaaaaagcaa caacaaacaa gattttatcc gttagtggat tgaaaacagc
    36001 ggggcaaatc aattcagcga ttgcatttgc taatgaagta aaaaaggaat atggagaagc
    36061 tgctatttct actaccggcc attcattagg tggattctta gcattatatg tagcagcaga
    36121 gaaacaatgg aaaaatgtcg gcttcaacgg gccggacccg tatgatctct tatcaccaga
    36181 agcaaaaaaa tgggtggaag aaaatcccgg tatgctcacc aattaccgaa atcacgccga
    36241 ttttatcggt aattttggtg gtaatggcac aggtgctgaa gttcggatca gtatggaaac
    36301 agcatacttg aatctgcttg cttcccacag tttaacctct tggaagtttg atgaaaatgg
    36361 aaagctgatt attcctgaaa atgaaaacaa tgttaaagct cgaaaacaac agaaagaaaa
    36421 ccaagcgacc cagttgtttt cctatcagtt gcaagaactg aacaacatac gtaaaaaact
    36481 acgattaagt ggcggccggc tgacagttaa tgaacaaatt tacttagatg acacacaagc
    36541 taggttagtg gtggaaaagt tatcggtaaa aatgaaaagc gctatggaag aagttatccg
    36601 catcaaccaa agaggaattt ttgagctaga gaaaaaatgg caagaaggct tgcggcaagc
    36661 acgtgttgtc gccccttcgt tgactgaaca ggaaatcata gaagcattag ctagtgtggg
    36721 cgccacaaaa gagaacttag tcgattctgc gaaagaagtc tatctgctac gaatcaataa
    36781 ggcaagacgt atgggggagg cctttgatac attggcgaag gagatccaag acaaaatcaa
    36841 tgaaatcgtg gcacgagatc gagaattagc acagcaattc aattaaagga gaagtagatg
    36901 aaactagaag aattggaaag agattatcga agtgaacgaa gacaattaga agctcaagaa
    36961 gatgaattga tccactttaa gaatcaagga ttacgattga tggagcaaga ggagcagcga
    37021 ctgcatcatg tattaaagaa cttagcttta gataatgagc ctctgtttca agcaagacga
    37081 agttattcga attatcagga gcattatcaa caagccctac aagtagaacg acgaaaactc
    37141 tatcagcagc aagacgaact agaacgttcc tatcgtcaaa aaatcagaca aataactatg
    37201 gagaaatcat cttatgaatg aatttttaat gcaattacta aaagaattag agaaaaatct
    37261 acatcgatca aatgtacgtt cagttggtat ggggatatct cagcaaactt gggcagaaaa
    37321 acgattgaca gatcaaaacc accaaatgac tgcagaagaa gctactcaag aattttctaa
    37381 ccgacatgca cacttaaaag aatcagtaaa agggcaattt gcagaaaaac taaccgaatt
    37441 attccaaaga caagaaaaga aattaaaaca gtttcgttag taaagttata tagaaaaatt
    37501 ttgtgaaaat ggtttttcac atttttacat aaatttgtct taatatcgta gatgtaagct
    37561 tttgaacacc atttattcgg aaaaagggag ctgtgacaag atttttgtcg cagctccctt
    37621 taattctgat taatctatta gatcaatcat ctttatcgtc tgattctttg gtctctggat
    37681 tcgctctagc ataagctgaa gcggtgttcc agtaatctgt atagttttca tcagtaccgc
    37741 caacgccgaa tttaaaggcg cttttcttcg gaccattttt tgcccaaagt gattccactg
    37801 tttttcctgg cgtttggata gattttttat tgacagtaac ttttccagct gtttgtcctg
    37861 tgaacccaga tacttttttc ttcatcacat cggatgataa gtcaaatttc tcatcagtgc
    37921 cgaaaatctc agggtttgct tggtaagctt gattgattag attggcaaga taattagccg
    37981 aacgtattct tgcttggctg tccattccag tattgtcatc gtgtcctgcc caactactga
    38041 tagtgataga tggagttgag acgatcagcc atgaatctcg gtattcattg gtagaaccag
    38101 tttttccgac ccaatctgca tttcctagat ttccgtttaa gcttgagatg acatctttga
    38161 atggtgtagt gattttttca ttgatcacac tacgcatcat gtcattcatg atcgatgccg
    38221 ttgcttcgga ataaatacgg acagaattac tttcatgttt ataaatcaca ttacctgcat
    38281 tatctgtgat ggaatcaatg atatagcctt cttcgtagac tccaccattt gctaaggcct
    38341 ggaatccatt tgtctgttga agcgtcgtta catctactgt ccctaaagga gccgattcaa
    38401 cgccccaatt atcatttgct gggtagttca tcttcgccaa gtagtgctcg taagcgtatt
    38461 gtttcgatcc accggaattc aacacatctt gatataagtg ataagctggg atattgttgg
    38521 accattccag tgactcacgg acggtttgga aggtgttcga cccttcattg gtcgcattga
    38581 cgattttctc accagcattt tttccttctt gccaagtcgt tgcataatct gatacacggg
    38641 attctgatcc gacaagtccc atatcgattg caggaccgta aacaagaacc ggtttgatgg
    38701 atgaaccagc ttgacgttct gtatcaaagg cgtggttatt ttgattctgg ctgtaattcc
    38761 gaccacccac gaagccatag atacgtccgg ttctgttatc catcaataca tttccagtct
    38821 ccacttggct accagcacca tcatctaaca tgtagccata attttctacg ccggtttgca
    38881 atgcagcata gatatcttta tcaatcgtcg aatggatcgt atatcctttg ttttggatcg
    38941 tttgctgtgc tttttgataa taagcttcac tgaccgatga atctgacata tcagcattat
    39001 ctttttctgc caattgttgt gcaataatcc ttgttgcttc gttcatcacg gtataataca
    39061 agaattctct gtcagtctgt tccgcgattt gttgtgggag aaagtctttt gtaagatcat
    39121 aggctttcgc ttcttcgtat tgttctttcg taatttgtcc ttcacggtac atactgaata
    39181 aaacaaaatc ttttctggca agaccggcag aaagatcttc ttttagcgcg cctgtattcg
    39241 tgtatggact atacgtgata gggctttgag gcaaaccagc gatataagca gcttgcggca
    39301 gagtcacatc ctttgcatct acaccaaaga ttcctctagc agcttcctgg actccagcaa
    39361 tattttgccc cttattattc cgaccaaatg gtgagacatt caaatacgta gtaatgatct
    39421 catcttttga aaagtgtttt tctacttgtg cagaaagaac gatctcgttt gctttacgtt
    39481 tgaatgttgt ttcatcggtt aggatctgtt gtttgactaa ttgctgtgtc aaagtggatc
    39541 ctccagacga gccgatgcca gtcgcttctg aaactagtgc tcgtaaaaca gctttaggga
    39601 cataaccttg gtgtttatcg aagtattcat cttctgtact gataatcgcg gttttcaata
    39661 aaggcgaaat cttatcagat gaaatagtcg tccgcatcag atctgtctgg atttttgata
    39721 tctctgtatt atctgcataa acaatctttg acgtttccgt aatgtttcct agttctgtct
    39781 gcagttcttt tttagtcggc aattgtgtgt cttcgacaag ataggcaaag tagccagcac
    39841 ctattccgat acctagagct gcgaacaaca aaagaagaac agtaataaaa acagtcaatg
    39901 attgaaacac tctaaaaata atcttaggaa caaaccattt ttcttttttt cttctattct
    39961 gtttttttcg agtatttttg cgtggcaaaa gggtcacctc aactaatggt tttatttcgc
    40021 taattatagc aaataatagg acaaaaaaac agacaaggct gtttttgaca ggaatttctt
    40081 tttcgaatga gataaaacgt gaggaaatga tcttttttat gaaagagttc ttaagctttt
    40141 ctttagggaa agtttcagtt actatggaga acagggcaaa gaaaaacaaa ctattttctt
    40201 tgtacatcat cttatcaata tacaggaatt gttcgaaaca attgcctttc aaggaggaat
    40261 ccatccatgt tattaggctc acacgtcagc atgagcggaa agaaaatgct gttaggcgcg
    40321 gcagaagaag cagccagtta cggatcttcg acctttatga tctatacagg cgctcctcaa
    40381 aatactagaa gaaaagctat cgaagagatg aatattgatg ccggaaaagc atttatggca
    40441 gaaaacggac taacaaatat cgtcgttcat gcgccttata tcattaattt gggaaatacg
    40501 atcaaaccag aaatgtttcc atttgctgta caatttctga gagaagagat tgtccgtgcg
    40561 gaagctttag gtgctactca aatcaccctt cacccaggcg ctcatgtagg agcaggggca
    40621 gaagctggga ttgctagaat tattgagggg ttgaatgaag ttttgacaaa agaacagacg
    40681 gcacagatcg ctttggagac gatggcaggg aaaggtacgg aaatcggtcg aacatttgag
    40741 gaattagcgc aaatcatcga tggagtaaaa ttgaatgaaa aattatccgt tacttttgat
    40801 acatgtcata cgaatgatgc cggatataat ataaaagaag atttttcagg tgtaatggaa
    40861 gagtttgata aggtcatcgg attagatcgg cttaaagtac tgcatatcaa tgattctaaa
    40921 aatcctcaag gttctcataa agatcggcat gccaatatcg gttttggaac aattggattt
    40981 gacacattga acaaaatcgt ccatgatcca atgtttgaca acatttcgaa aatattagaa
    41041 accccatatg tcggtaaaga taaaaagaaa gcttacgcac catatggaaa agaaatttcc
    41101 atgttcaaag cgcaagcatt cgatcccgaa gtgttccctg agttattagc agaagaagtc
    41161 acactttaag ttttctacct gacagcaaca aaaaaggatt gggcagtctg ccttgtcctt
    41221 ttttgtttaa gaaacaaagg agtgcttttt gcattcgttt tcgccatgct ccttttgccc
    41281 cctcttttta aattcagaca aacagggtat actgatagaa aagtaaaaaa cgaaaagttt
    41341 cacaaacaag tagcaaaacg tgattgaaag gacgaaaaga tgctgaacat tttaaacccc
    41401 ttgatcgacc aactaaaaaa gaaacataca tactttattc ttggcatagc cgtattattt
    41461 acaattattc ggttgtattt atatagtaaa gcaatctatg gaacagatat gtcggcgacc
    41521 tatgatgatc agctgctgat tcactatgct caaaatattt tggatggtaa atggctaggg
    41581 gagtacacga ctacgacact ttcaaaaggg atttcctaca gcttgttttt agtacttgca
    41641 cataaactgc atctttctta tgcagtttta ttcggcatgt tcagtattct tgccagtata
    41701 ttggttgcac tagcgtttaa accaatcgtg aagaacaagt atcttctttt aagtatctat
    41761 ttttattttt tgttttctcc gattagtttt acacatgaat attccactcg aacatatcgt
    41821 aatgctctcg tgatcccgac tgttgagatc attatcgctt gtttactagc tatttattac
    41881 cgcaaatata attccagcaa aaaattgctg ccgtggtttt tagggctagc tgtttctttt
    41941 cctttctttt ggttcattcg cgaagattcc atctggcttc ttccttttac tgtagtcgcg
    42001 ttaggcatca gtttcgttca gatcttgcta ggacaagact tttctttcaa agaagcaaag
    42061 aagttaaaag aacgaccatt tctcctttcg aaacaagaat ggctgaaact ttcattgttt
    42121 ttactccctc tagtcggttt ctccatcgtc tatcagtgga tcgaatataa aaacgagaca
    42181 acatatggta ttgcagccat caatgaccgt tcgagtggcg aatttggacg tttgatgaaa
    42241 cagctgatcc gaatagatga cgaaacaaac ttaaataaag aaaacagtga gatatgggtc
    42301 tcgcatgctg cattaaataa agctttagac gcatctccta catttcatac tgtttctact
    42361 cgtattgacg aattgtatac gactcatgcg tggacccaag gcggaaaagt aaaagaatta
    42421 ccaggagata tcattttttg ggcattgcga gatgtggtaa gcgaatctgg ttattaccaa
    42481 aacaatgcaa aagaaaccaa tgatttttgg aaaaaagtca atcaagaatt agaagaagcc
    42541 tatcaaaagg gaactatcaa aaagaaaaaa gaattctatc tgatgggatc aggggatgga
    42601 aagacgatga atgatctgcc aatcgtattt gattttctga aatcaggata tgcttatgca
    42661 tggcgataca aagatttcca tcaagggggg aattatagtt ttgggacgca agaacaagtc
    42721 gaacaggcac aagaattatt gaagcttcca ctaatggata attggatcga tagcagtgat
    42781 ccgagaacac ctgatttcca gttgacaaaa acagcaaaag tcgcgaatgt catgataaaa
    42841 atttaccaag ttctggccat tcccgtgctg attgcttcaa tagcagggat attacttatg
    42901 atactaggaa ccgtatttgc aaaagctgat cgtgcctatt atagttcctc tttgattgta
    42961 gtcatcggat taatactgac acaattggtt tttcttttcg gtgtctcgtg gttttgttct
    43021 tatgcgccag aaaaaaagga ttatttttta agtgtctaca ctggcgcagg cgtgccatta
    43081 acgcaattca tcgcagtaac aagcatgcta gtttttagta aattgaatct gaaaaaagct
    43141 ttatcttcca aataaaaagg gaactgtgac aaaagtcttg tcgcagttcc tttttccgaa
    43201 taaacggtgc tcaaaagctt gcatctgcgg taataagctc aaccaaacgt aaaatatgag
    43261 gaactatttt tgtttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct
    43321 gatacacggt gttccagaag taacttcttc ggaaataagc cgaaatttca caaaaatttg
    43381 aaaagcaatt ttcttaaatt ccttcttatt tcttgaagct gcccacttct gtcacaacct
    43441 cctttgtgta aaagaatcag tttctattcg atttcttcta tcgtttcttg caaacgctgt
    43501 tcatattttt tgtttccttt atataaatca ccaatcgtcc atgccaacag gagaaggaca
    43561 agaacaatga ttacataggc gatttgatca gccaatgcta gttgagctga ggtggcttgc
    43621 tcgccgaaga aactttcgat ttgacctggt aatcctcgta agttcaagta agtcagacta
    43681 atcacagaga accagccaag aagttttaca acaaatgaat ttttgaatcg gctccccatc
    43741 tccgcttggc tattggtcat catcagtaaa ggaatcatcg agaatggcaa tgcaaaagcc
    43801 agaaaaactt gggattcatt catcaagtta ttcaaagcgg tatgttcttc gatcgttcct
    43861 tttgtacttg taaacaaaac acaaatcaat acaggaatca cagaaagcaa tcgtgtgact
    43921 agtcttctta gccaaatcgg gatacgcata tggatgaatc cttccatgat gacttgaccg
    43981 gtcaacgtac cagtaatagt agagttctgg ccagaagcaa gaagtgctac agcaaataaa
    44041 gtagacaaga taccagattt tgctacagca atcaagatac cattgctcat agctgatgga
    44101 tcagataaag cttcatacag accaaaaaag gaaggatctt ggacagaacc ggttttgaat
    44161 acagcgacac ccatgatcaa tagcagtgca ttgactaaaa aagccattga caactggata
    44221 ttagagtccc aagtagaaaa gcgtaccgct tgtgctacat cttcttcgtc ttggtgatcg
    44281 atcttccgag tttgagaaac tgctgaatga agatataagt tatgcggcat gactgttgca
    44341 ccaataatcc ctaacgctcc agtcagcgga gtttcaccac ctatgacagg tgagtctgag
    44401 aatgtatgac tgttagggat aaagccagca aataaactgt gccaatcagg gttagacaag
    44461 ccaacttgat agacgaaaac gaataaaatg acgaaaatca agcagacaac caaagcttcg
    44521 attttacgaa acccgacttt tgtcagcaat aaaaggacga aaacatctaa cacagtgata
    44581 aatacggcaa ttaccaatgg aatatcaaaa agtaagtaga gggcgattgc tgcaccaatg
    44641 acttctgcga tgtctgttgc cataatggct aattcagtca agatccataa aatgacaccc
    44701 aatgtcttac ttgtccgtgc tcggattgct tgggccaaat ccatttgggt cacgattcct
    44761 aattttgctg ccatatactg taaaagcata gcaattagac tagacatcaa aataactgac
    44821 atcaataaat attggaaatt ttgtccacca gtgatcgaag tggaccagtt acctggatcc
    44881 atataaccaa ctgctactaa tgcacctggt ccagagtaag caagaagtgt tttaaaaaaa
    44941 ctttttccct ttggtacatc cactgttcca tttacttcag ctaaagataa accatttgta
    45001 tgttcaataa gtcgatgctt atgaaattgt ttgttggatt gattattcaa gaaaaaacca
    45061 cctttcctat ttatctacga ttacattcta cacctcagaa agaaaaaatt aaagaaaaag
    45121 attcggtatg cctaattttt tttcgtggcg tgtcttgctg gttaatgaaa gaaattttgt
    45181 tcttctctaa aaaaaccact attttttgca tgaaactaaa gaatacgcct ttcttttttc
    45241 aataaacttt agtaaaataa atcattgaga gcaattcgga aatagaaagg agagatttat
    45301 atggtatcaa caggtattgt cgtacttatt gctattattg ctttgctaat cggcgcagta
    45361 ggtggctttt tcctagcgcg taaatatatg aaagactatt tagaaaaaaa tcctcccgtt
    45421 aatgaggaca tgttgcgatc aatgatgatg tcaatggggc aaaaaccatc tgagaagaaa
    45481 attcgccaga tgatgcagca aatgaagaac caagggaaaa aataggttct gacccaaaga
    45541 ctttttgcgg gctgattttt tcagtccgtt ttttatttcg taatttgtta gactattcag
    45601 actattcagc aaaaaagaca aggacagaca atcctatgct cttgataaag acaaaggagg
    45661 agtaaaatgt cgatttttag aaaattaggt tggttttttc gtcaggaaaa gaaacattat
    45721 ttaattggga ttttctccct attcgcagtg gccttggtac agttagttcc tccaaaagtg
    45781 attgggatca tcattgatga gatcgccgat aagaatttat caataaagat catttcttgg
    45841 tggatcttac tattgatcct tgcagctttc ttacaatatc tttttcgtta tatctggcgg
    45901 acgaatattt ggggaagtgc agctcggttg gagaaagaac ttcggcagca gctattcaaa
    45961 cattttacag aaatggacaa tctcttttac caaaaatatc ggactggaga tttgatggct
    46021 catgcaacga atgatttgaa tgcaatccag aatgtagcag gagctggaat cttgaccttt
    46081 gcagattcag tgattacggg cggaacaacg atcattgcga tgattttgtt tattgattgg
    46141 cgcttaacac tgattgcgct gattcctctg cctttgctag ccgttacttc acgagtgctg
    46201 gggtcaaaac tccacgatgc ttttcgtgat tcgcaagaag ctttttctag tatcaatgat
    46261 aagacacaag aaagtatcac tgggatcaaa gtcattaaaa catttggaca agaaaaagaa
    46321 gatctcgcgg attttgaaga aaagattgaa gatgcaatta ttaaaaacaa acgagtcaat
    46381 tttttagact ccttatttga tccattcatt accttgatta tcggtctgtc ttatgttgca
    46441 acaattattt taggtggaaa gtatgtcttg gaaggcacga tctcgattgg gcagatggtc
    46501 tcatttatta gttatatcgg tatgcttgtt tggccgatgt ttgcgattgg ccgattgttc
    46561 aacgtattgg aaagaggaaa tgcttcttat gatcgcgtta atgaactttt gcatgaaaag
    46621 acgcatatcg tggaacaact gggtgcagtg cagaccccgg caaaaggcga gctgaatgta
    46681 gctatttcct cttttaacta tccgaaagaa gaatcaccag cattagaaca aatcaaattt
    46741 gcgatccaag aaggagaaac attaggtatt gttgggaaaa ctggtgcggg aaaaacgaca
    46801 atcatcaaat tactgatgcg tgaatacgat gattatcaag ggaaaatcca atttggcgga
    46861 cgttcgatca aagaatattc attgaatgct ttattaggat caatcggtta tgtgcctcag
    46921 gatcacttcc tgttttcgat gaccattcga gataatatcc gtttttctaa tccaaaactt
    46981 tcagaagaag aagtagagca tgcggcttct ttagcattta tcaacaatga aatcaaggaa
    47041 ttgccaaaag gttatgatac cttagttgga gaacgtggag tctctttatc tggcggacag
    47101 aaacaaagga tttcgattgc tcgagcattg atcaaaaatc ctgaattgct gatcttagat
    47161 gatgcacttt ctgcagtaga tgccaaaaca gaagaagcta tcttgcataa tttaaaagaa
    47221 ataagaaaag agaaaacaac catcattgca gctcaccgtt taagcagcgt gatgcatgca
    47281 aaagaaatca ttgttgtcga tcaagggaaa atcattgaac gaggaaccca ccacgagctg
    47341 cttgcattag gtggctggta tgaacgaatg tgggaaaaac agcaattaga agcgaagata
    47401 gaaggaggcg aggcctgatg gatgaaaatt atcaatcgga atggacaaaa tcgattccac
    47461 ttaaagaaca gaagaagatc atcaaacgac tgatgaagtt cgccaaacct tttagaagaa
    47521 cgttcatcgt tgctatctta tttgcgtttg ccctgtctgt gatcaatgtc ctattgccaa
    47581 ggatcatcca aacttttatg gatgatcatc tggctaaaca gtcagctacg acacaagtta
    47641 ttttgttttt tgctggtgtg tacttgtttg gagtcatagt caaaagtatc atttggtttt
    47701 tccaatggta tttgtattcc atggcttcat tgaagaccta tcagtatgtt cgggtaagat
    47761 tatttgaaaa gctgcataca ctaggtatgc gttattttga ccagacaccg gcaggatcga
    47821 ccgtttctcg agtgacgaat gacacagaaa cgctatttga attttggtat gtctttttga
    47881 tggtattgac tgggatcttt gcagtcgttt cttctttcgt tgccatgttt caaatcaatg
    47941 gagaaattgc cttgtggact ttggtgttct tgccgatttt aggaatcgtc atctggtatt
    48001 accagaaatt cagttctcgt atttaccgaa atatgcggga aaaattaagt cagctgaaca
    48061 cgaaattgaa tgaatcgatt tccggcatgc gtattatcca gcagtttcgc caagaagctc
    48121 gtttagctaa agaatttgaa caagtgaaca acgagtattt agacacgcgc tatgcgatga
    48181 tcaaaacgaa ttcgattctg ttaagtccga tcatcaattt tctctatgca ttggcgattg
    48241 cgttggcgtt gactttgttt gggatcgatg cgttgcattc tcccgtagaa gttggactga
    48301 tctatgcatt tacgacctat gtccagggat tttttaatcc aatgtctcaa atgatggact
    48361 ttttgagcac ctttacagat gggatggttg ccggtagtcg tattttgaaa atcatggata
    48421 cagaagaata tgcaccgcaa caaaatcctg gagcagatca agcgattact tcaggtaaga
    48481 tcgagtttcg caatgtaagc ttttcttatg atggagagca caatgtattg aacaatatct
    48541 cttttgtcgc taatccgggt gagaccgttg cattagtggg gcacaccgga agcggaaaaa
    48601 gctcgatcat caacgtattg atgcggtttt acgaatttta tgaaggccaa atcttgattg
    48661 atgatcatga cattcgagaa tatccaatgg aagagttacg taagaaaatg ggattggtct
    48721 tgcaagatgc cttcttgttt tatggagata ttgcaggaaa tatccggatg atgaatccag
    48781 ctatcacaga cgaacagatt cgccatgcag ctgagtttgt tcaagcaaac aagttcatcg
    48841 atgaattacc aaaaggatat cactcaaaag tgatcgaaca cggtgccagc tattctagtg
    48901 gacaacgaca gctgatcact tttgcgcgaa caatcgtgac agatcctaaa atactagtat
    48961 tggatgaagc aacagcaaat atcgatactg aaaccgaagg attgatccaa gaaggattgg
    49021 caaaaatgcg acaaggacgg acaacgattg cgattgccca tcggctgtcc acgattcggg
    49081 atgcagaatt gattttagtt ttagacaaag gtcatatagt agagcgtggg aatcatgaaa
    49141 cacttctagc gcaaaatggt ttgtatgcag atatgtacaa actgcaaagc agtggtgtgt
    49201 aaaaagaggt tgtgacagta gcatagtagc attttgtcct aagcgctaga gtgaaaataa
    49261 aacagagctt cccagattct tcatctgtga gcgttagtgg cgtagtcacc cgatttaaaa
    49321 aagacgacga cagctagtca aaagtgccta atagccacta agaaagcgtt gacaaaagcg
    49381 tttgctttcg ataatataaa gaaaacgata caacttggat agtgattgcc tgatgcaagc
    49441 taaacctgat gagtctccca tggttccatg gacggctttt tgggtttttc tttttgtttt
    49501 gaatacagcc ctatatatca tggaaaggag caaaacatgc tgattgagaa agtactgaat
    49561 aacaacgtcg taataaccag ggatgaaaga aatcaggaaa tgatcgtgat gggaaaaggt
    49621 ttggcattca aaaagaaagt gggtgacccg atttttgact catgcatcga caaaaaattt
    49681 cagttgacaa atgacgggct ttcacaacag ttccaagaat tggcacaagc gattcctctt
    49741 gagtacttag aaatttcttg tgaaatcatt gaatatacaa aagaggctct acaagtccag
    49801 ttgaatgatt ctgtgtatat tgcattgacg gatcatttgt atacggctat cgaacgtcac
    49861 aaaatgggaa tatttgtacc aaatgtattg ctgtatgata tcaaacaact atttcctaaa
    49921 gagtatgcca tcgggaaaaa aacagtgaag aaaatctcgg ataaatacca catcaagtta
    49981 tcagaagatg aagccggatt tatcgcattg catttagtca atgcacaagg cattcaaagc
    50041 caacaaaaca atacctacct gtttactata acaatacagg atattctaaa tatcgtccgc
    50101 tattactata agattacatt tgatgaagat tcagtccatt tttttcgatt cgtcacacac
    50161 ttacgttttt ttctgacacg cgtcctagat ggagaaaaat cagaagtggg agaagtttct
    50221 gaggaattgt ttcaggttat tcaaaaaaaa tataaggata cgtttggttg cgttgagaaa
    50281 atagcagact ttttagccga gacgttcaac taccagatgt ccacggacga aaaaatgtat
    50341 ttaacgatcc atactgcgcg tttagtgcat gagaatcgtt gtaaataaat aaaaaaagga
    50401 ggataaatta acaagaacgt atgaaataag ggtagtgaca ttcagttggc taaaccttcc
    50461 actaatatat tggagggaat agaaatggga aaataccaag aattagcgag aaaaatcgta
    50521 gaaaatgtcg gtgggaagga aaatatcaat ggtttgacac attgtatcac aaggcttcgt
    50581 ttcaaattaa aaaacgaaga aaaagcaaat gatgagatct tgaaaaatat ggacggtatt
    50641 gtaacggtaa tgcgagcggg agggcagtat caagttgtca tcgggaatca tgtgccagtc
    50701 gtgtttgaag aggttataaa agcaggaaac cttacttttg atgaggctgt ttcaacagaa
    50761 aaaatgagac cgtttgatat gcttattgat ggaatatcgg gctgtttcca accattcctt
    50821 gctatcttag ctgctggcgg gatgattcgt ggactgacag cattccttgt cttcttaggc
    50881 gcgtttgacc gcggttctgg cacatttgtt atgtttgata atatcggtga ttctgtattc
    50941 caatttatgc ctgttattat cggtttaaca gctgcccgta aatttaaagt aaatgaattc
    51001 gtagggatgt tgcttggcgc agcattaatg aatcctagct tgtcgctgga agctttgagt
    51061 ggtgcagcag aagcaccact aacgaccata ttttctggca ctatttttga agcacctatt
    51121 tatcaaacag tattcggcat tccctggatt gcgcgtaact acgcttcttc tgtcattccc
    51181 attatcttta ttgtgttgtt agctagccaa attcagaaac caattaaaaa gttagtacct
    51241 gagatgatcg cgaatttctt cgttccattc ttcaccgttc ttattacaat gcctttaggt
    51301 tttttactcg ttggaccagt attcacattc gcaactgata ttttaatggc tggatttgaa
    51361 acacttttag cactttcgcc agttatttat ggagcaatcg taggcttctt ctggcaaatt
    51421 ctggtgatgt ttggtctcca ttgggcaatc gtaccaatgg gattgatgca attttctgtg
    51481 aatggttggc aaaatattat gacacctgtt gcagtagtgt cttttggaca aactgcagca
    51541 cttaccgcac tctactttaa gcttagaaat ccaaaagaca aagcaattgc aataccagcc
    51601 attgtttctg gtattgtggg gattacagag ccagctattt atgggtttac attaccacgt
    51661 aaaaaaatat ttatttttac ttgtgtcggt ggtgcgttag ggggcgcgta tagtgggtta
    51721 atgaatttaa cttcttggaa tcaaggtgga ctaggcatct ttacaattcc caactatatt
    51781 agaccagatg gtgatttaac agatgtgatt aatgtattga ttgggatcgc cattgcgatg
    51841 gtggtatcct ttgcgctgac ttttttcttt tggaaggagg aagcaggtga aacagatgac
    51901 agacagaaaa gatcaggtaa agaaattgta aaaacaccga tacaaggaca aatcgctcca
    51961 ctgaaagcag caaaggatgc agcttttgca caaggaacac taggtcgagg aatcttgatc
    52021 taccctgaaa aaggagaagt acgtgcccct tttgacggaa cagtcatgac cctgttcccc
    52081 acgaaacatg caatcggaat ggtttctgaa acaggtctgg aattgctgat tcatgtcgga
    52141 ttggatactg ttcagttgga agggaaatat tttgaaagct tggtgcagca aggagaaaga
    52201 gtgaaacaag gcgatctgtt gctccgcttc gacaaaaaga aaatcgaaaa ggaaggatac
    52261 agtttagaaa cacctgtaat cgtcaccaat tacatggatt atttggatat tttggaaaat
    52321 caaggggaga cggtcgggcc agacgatgca cttatcaccg cactgacctg aacggttagg
    52381 tgaaagaatg gaatagactt aactattctt tttagtccac ttctttattt tcaaaattga
    52441 aaggctcttt catgatggct gagctgatag ggcgtttatc aaatttttgt cctacagaaa
    52501 ttagatggac taaattctgt tgataatttt ctgcaaaaac acaactatat aacacgtcta
    52561 gaagataaca aatcgatgta ttgatcgtaa aattaccaat ttttgaatac agtcgttcgc
    52621 gtgtcgtaag tcgcaaagcg gctgtactca ttgaggatag cgttgaatca ccgatactgg
    52681 tcaacgctaa aattggaaca tgattttgtt tcaatatttc tgcggtacga aggatcacat
    52741 tgttttcacc cgtataagaa atcagaatcc cgcacatatc actcgtgcaa ttgtacgctt
    52801 catagaacga ttcaccaaaa gtggtgacaa tcgtgacatc cattttgatg cgcttcattt
    52861 tcagcatgaa atcttgagaa atcaaagtat tcgagttact ggcgaaaatc acgatttttt
    52921 ttgcttgaag cattagttgt ttggcttttt gcagttggtc atgatgaatg agagaaagtg
    52981 tatcttgaat cgtcatctgt tctaaagaag ccattttatt tgcgatcgtc ataataccgt
    53041 ctgtggtgga aaaaggaaga ttcgcatcta cgtcttgaaa attcccttca agataggctg
    53101 tttcagctaa aaaagcatta cgaaaactga cccagccatc aaaacccatt ttttttgcta
    53161 cacggatgag tgtggacggg tggacataac atcgctcagc aatctcttgg atggtcattt
    53221 cgccaagtgc tggagaatcg cttaagagaa actgaatcac ttcattttct gaaggagaaa
    53281 aggagatttc tttgattttt tcacgtaata acatgtagat accttcttct agttttttta
    53341 cgtaaattat aacttttttg aaaatgattt gtaaacggat ttatgttata tagcttaata
    53401 aagtcatttt ttgacaagat atttacaaaa atccagtaga aaacactaac ttttgtaaat
    53461 gttactggaa agaaacgaat ttctattgtt tgttttgttt acaaaaaaga taataaaagt
    53521 gtaaaaagca aaggagtgag aacatggcaa aaggaatcaa aatcgctacg attggtggag
    53581 gcagcagtta cacccccgag ttgatggaag gatttatcaa aagatatgag gaattaccga
    53641 tacgagaaat ctggctcgta gatgtagaag aaggaaaaga aaagcttgag atcgtcagtc
    53701 agatgtctca gcgtatgtgg gatgcttctc cgtatgaagt caagatctat gcaactttgg
    53761 atcgggaaga agcattgaaa gatgcggatt ttgttacgac tcagtttcgt gtcggtcaat
    53821 tagatgcacg aatcaaagac gagcggatcc ctagttatta tgggatgatt gggcaagaaa
    53881 caaatggtgc tggcgggata ttcaaagctt ttcgtaccgt tccagtggtt ttggcaatcg
    53941 ttgaagacat gaagcgttta tgtccaaatg cttggctgat caatttcgcg aacccaagcg
    54001 ggatggtgac agaagcagtt atcagatatg gcaaatggga taaagtgatc ggattatgca
    54061 atgtgccagt aatggcgacg atgacagaac cagcaatgct tggcaagaaa aaagaagagc
    54121 tgatctacaa gtttgccggt ctaaatcact tccattggca caaagtagca gataataaag
    54181 gaaatgaccg cacagcagat ttgattgatc gtttatacga tgaagacaat ggattgccga
    54241 aaaatatctt tgacatcccg tttttcaaag aacaattaaa acaaatgaac atgatccctt
    54301 gtggctacca ccgctattac taccgtgaag aagaaatgtt ggaacatgct ttagaagaat
    54361 atcaaacgat tggtacaaga gcgcaacaag tgaaagaaac agaagcagag ctgtttgaat
    54421 tatacaaaga tccagaattg gatcataaac ctgaacaatt gcaaaaacga ggtggtgctt
    54481 attattcaga tgctgcctgt gaaacgattg cttcgatcta tggaaataaa gaaacacaga
    54541 tcgtggtgtc tacaaagaat gatggagctg ttcctgatct gccggcagat tgtgtagtag
    54601 aagtcactgc ctatgttggc gcacaaggcg cacgaaatgt agcgtttggt tcccttcctg
    54661 ctgctgaaag aggctggttg caagtaatga agaatatgga attgctgacg atcgaagcag
    54721 ccgtgactgg tgattatgga acagctttac aagcgtttac gatcaatccg cttatacgat
    54781 caggaaagac agcaaaacgg atcatggatg agttgtttat tgcacatcag cagtatttac
    54841 cgcaattcaa ggaaacaatc agccggttaa aagcagaagg aatcgaagtc caagatgaac
    54901 tggcaagaga attgtcaagc aatacacatg taatggagga agtatgatgg gattcagaaa
    54961 agatttttta tggggcggtg ctacagcagc caatcaatgc gagggtggtt atgatgaagg
    55021 cggacgtggg ttagcgaacg tagatgttgt gccaatcgga gaagaccgtt ttcctgtcat
    55081 tactggaaaa aagaaaatgt ttgaatttga taaagatcat ttttatccag caaaaattgc
    55141 gatcgatatg tatcatcatt ataaggaaga tattgctttg tttgcagaaa tggggttcaa
    55201 gacttatcgg atgtccattg cttggagtcg tatttttcca atgggcgatg aaaatgagcc
    55261 aaatgaatct ggtttgaaat tttatgagga tgtctttaaa gaatgtcaaa agtacgggat
    55321 cgagccgctt gtgacgatta cacattttga ttgtccgatg catttgatca aagaatatgg
    55381 tgcgtggcgt tctagagaac tcgttggttt ttatgaaaat ctgtgccgag tcatcttcaa
    55441 tcgctataaa ggacttgtca aatattggtt gacattcaat gagatcaata tgatccttca
    55501 tgcaccattc atgggcgcag ggctgtattt tgaagaagga gaaaatgaag aacaaatcaa
    55561 atatcaagcg gcacatcatg agttggttgc aagtgccatc gcaacgaaga ttgctcatga
    55621 agtagatccg gagaacaaag taggctgtat gctggcagca ggagcatatt atccatacac
    55681 ttgcaatcct gaagatgttt gggcttctag aaaatcagat cgagaaaatt atttcttcat
    55741 tgatgtccag tcacgaggag aatatcccgc ttatgcattg aaagaaatgg aacgaaatgg
    55801 cattcagatc aaaatggaac ctggggatgc cgcattgctg aaagaacata ctgttgattt
    55861 tatctccttt tcttattatt cttctcgagt ttcgactact gacaacgaac tcttggaaca
    55921 gactgcagga aatatctttg cttctgtcaa aaatccatat ctggaagcaa gtgaatgggg
    55981 ttggcaaatt gatccattag gcttgagaat aacgatgaat gatatttatg atcgttatca
    56041 aaaaccacta tttattgtag aaaacggctt aggtgcagtc gatacgcccg atgagaatgg
    56101 ttatgtggaa gatgactatc gaatcgacta tctggcagca catatccagg caatgaaaga
    56161 tacagtagaa ttagatggag tcgatctatt aggctatacg acttggggat gtattgattt
    56221 agtatcagct ggtacaggtg agatgaagaa aaggtacgga ttcatttatg tcgatcgtga
    56281 caacgaagga aatggcacat tagcccgttc gaagaagaaa tcattcaact ggtataaaaa
    56341 agtaattgat tcaaatggag aaaatctttc gaatgattga tcaatgattt gtaaaagtct
    56401 attgtttttc agcggatttt tcgagtataa taaagctatt cgagaaacgc aagcagaaca
    56461 atagactttt tttcgcattg gctgtaaagt atgcttactt gattaagtaa aggagaatct
    56521 acatatgtat gatgtaatcg ttattggcgc aggtcctgct gggatgactg ctgctttata
    56581 tgcttcacgt tcaaacttat ccgtattgat gatcgaacaa ggcgcccctg gcggccaaat
    56641 gaacaatacg gcagaaatcg aaaactatcc tggtttcgat tcaatcatgg gtcctgatct
    56701 agcttataag atgtatgaag gtgtttcaag atttgggaca gaaaatgctt atggaatcgt
    56761 gcaagatatc aaggatcacg gcagccacaa agaagttatt tgtgaagata aaacttacga
    56821 aggaaaaaca gtcattatcg caacaggctg tatccaccgt aaattaggcg tacctggcga
    56881 ggaagaattt gctggacgtg gcgtttctta ctgtgcagtt tgtgatggtg cgtttttccg
    56941 taacaaacgt ctagtagtga tcggaggagg agactcagca gtagaagaag ccatctattt
    57001 gacacaattt gcttctgaag tagtcatcgt ccaccgtaga gatgaattac gtgcacaaaa
    57061 gatcatccaa gaccgtgcat ttgcgaatga aaaaatttcc tttatgtggg atacagtcgt
    57121 tgacgaaatc gttgggaatg aaatggtagt gacaggtgtg aaagcacgta atgtcaaaac
    57181 cggcaatgag tttgatttgg cagcagacgg agtattcatc tatgttggac tggatccatt
    57241 aactgcacca tttagagaag cagggttgac gaacgaagct ggctggattc caacagacaa
    57301 cgaaatgaag acgaatatac caggcgtttt tgccatcgga gatgttcgtg aaaaagattt
    57361 gcgacaaatc actactgctg ttggtgatgg tgggatcgct ggacaacaag tgtataaata
    57421 cttggaatct ttagaagaaa caactgcata agtttaaaaa gagtggaaga acggtttcaa
    57481 ttgttctttt actctttttt ttcgcgtgaa atctactgaa tccgatttat gcgaatactt
    57541 gcaaccgtgc ttgataaaag aatcctttct tgatttaagc gttttttaga cctcgtactt
    57601 tcatatctaa taagtgaatg ctatacttat taagaaccat atttcagaaa gaggtgttat
    57661 tttcatgtct tgggaacaag tgtatgaaca atgggtacat gaagaaaatt tagaagaaaa
    57721 cttaaaaaaa caattaattg atctgggtga agatcctgaa aaacttgaag atgcttttta
    57781 tgcaccgttg gaattcggta ctgcaggcat gcggggaatc ttaggacctg ggatcaatcg
    57841 aatgaacatc tatacggtaa gacaagcaac agaaggactt gcacgtttca tggatacaca
    57901 aggtgaagaa acaaaacgcc gaggtgtcgc tatcgcttat gactcacgcc atcaatcacc
    57961 agaatttgcc atggaagcag ccaaaacatt agcacatcac aatatccctt cttatgtatt
    58021 cgaaagttta cgtccaacac cagagctttc ttttgcagtc cgtcatttga agacgtttgc
    58081 gggaatcatg gtaactgcat cccacaatcc agcagcttac aacggatata aagtctacgg
    58141 agaagatggg ggacaaatgc ctcctgcaga cgcagatgca ttgacgaaat atgtccgtga
    58201 agtcagcaat ccgttaaaag ttgaagtatt atctgacgac gaagctgaac atagcggatt
    58261 gatcacgatc atcggagaag aagtggatgc cgcttatcta gaagaaatca aagcagtaac
    58321 gattgatcat gaattggtgg aaacaatggg taaagatttg aaacttgtgt acacaccact
    58381 tcacggaaca ggaaaaatgt tgggcgaacg tgcgttgaaa caagctggat tcgaacaatt
    58441 cgtactagtt ccagaacaag ctgtcgcaga cccggatttc actacagtca aatcaccgaa
    58501 tccagaagaa cactctgctt tcgagtatgc gatgcgactt ggcgagaaag aaggcgctga
    58561 cttactgatt gcaacagatc ctgatgcaga ccgtttaggc gcagccgttc gtttgccaaa
    58621 tggctcctat gaagtattga cagggaacca aatcggagcc ctgtttgctc aatatatttt
    58681 ggaagcacac caatcgcgag gcactttacc tgaaaatgca gcggtattga aatcaatcgt
    58741 ttctagcgaa ttgcctacag caattgcgga acactatggg gctaccatgt tcaatgtatt
    58801 gacaggattc aaattcatcg ctgaaaaaat tcaacaattt gaagaagatc attcccatac
    58861 ttttatgttc ggattcgaag aaagttacgg ttatttagtt aaacctttcg ttcgcgacaa
    58921 agacgcgatt caagcattgc tcttattagc agaagtagca gcttactata aaaaacaagg
    58981 caaaacgttg tatgacggct tgcaaacgat ttttgaaaca tatggctact acgcagaaaa
    59041 aacgatttct gtgacaatga gcggacaaga aggttctgca aaaatctctg ctttgatgga
    59101 aaaattccgt gaagaagcac cgacagaatt tgccggagca aaagtcatcc aaacagaaga
    59161 cttcaaagag ttgacgagaa cagaccgtga aggaaacgta gaaaaactaa cgacaccgcc
    59221 atctgacgta ttgaagtata cgctggaaga aaatggctgg atcgctatcc gtccttcagg
    59281 aactgagccg aaaatcaaat tttatatcgg tgtaaaagga aactcttcag aagacgcagc
    59341 tgaaaaagta gccgcttatg aagcgattat caaaaaaatg acagaagaat aaaaaaactt
    59401 gagactgatg gaaaaagtgg taaactttag aagtcagtct tttttcaagt tggaggtgaa
    59461 tggattgcca gacacgcaaa aaacaaaagt agagaaagtc agccaactat tcaaaatgtt
    59521 gagtgacccc actcgtctca aaattctgct gtatctgaaa gacggggaac aaaatgtgac
    59581 agcaatcacc caagcagtag aaatggaaca atctgctgta tcgcatcaac tgcgtttatt
    59641 aagagaaaac catgtcgtca agtcccatcg tgagggaaaa gcgattttgt atagtcttga
    59701 tgattctcac gtactggata ttttgaacca gacgctcaaa catgtggaac atcaataacg
    59761 ataggtgcaa atagagacaa actggactgt atcaacgaat cttcttcgct gacacagtcc
    59821 agttttttta agaaaaagac aagaaaaact gttagtctgt ttcttcggtg gtttcagttc
    59881 cataataact atgatcttct aggtctaaag cattcaaaat aagtgaagct gtttcttcga
    59941 tagataaaga agcgacattg attactacgc agcccaattt ttcataaaga tcattcgcaa
    60001 aatcgagttc agctcgtatt ttttcgatat cggaataagc agtatcagga tttaatccgt
    60061 aagagcgcat ccgttcttta cggatattgt ttaaaatatc tgggttattc gtcagtccca
    60121 cgattttttt aggatcgatc tcccaaagct gtttgggaat atgtgcttgt gggatcaaag
    60181 gtagattggc aacctttaaa tttttgttag ctaaaaacaa gctcaaaggc gttttggaag
    60241 ttctggatac gcctagcaaa acgacatctg cttctagaaa cccacgagga tctttcccgt
    60301 catcgtattt tacagcaaat tccattgctt tgatccgttt gaaatagttc tcattcaata
    60361 aatgaagggc gccaggttgc cgaatgggct tgataccagt taagcgctcg atttctgata
    60421 tcggcggagt catcacatca aaactaaata attgatgttc ttcacaaaaa gaacgcgtca
    60481 tctcgatcaa ttcttgattg atcaatgtgt gcaggacaag ggctttttct tttagtgcat
    60541 cttgcagtgc ctgcatcaat gttttctcat ctgtcacaaa tgttctgcgg aataaattga
    60601 actcaacggt aggatattgg gccatagtgg cttgcgctaa ttttgtcgca gtttctccag
    60661 cagagtcaga gatgacaaaa aaagtaacga tttctgtaga atcggaagac atggataaaa
    60721 cctcacttgc atttttttta tgtttattat accatactct agaatgtgta cttcgtaatc
    60781 attttgattt ggaggaataa gtcatgaaaa aacagacatt gattgaacaa tcactagaaa
    60841 cattgaaaaa taacggtttt aaatatacta aaaaaagaga agcattgtta acttatttag
    60901 tgaagcgcaa tcgctacgta tccgctaaag aagtttttga ctatatgaat caggaattca
    60961 aaggagtaag ttacgatacg atttatcgaa atctccatga ttttgcagaa atcgatttac
    61021 tggaagaaac cgatttaaat ggagagatga agtttcgttt tcattgctgt caaggggaaa
    61081 tcggccatca ccatcacttt atctgtacgg tgtgcggaac aacgaaagaa atccatatgt
    61141 gtccaatgaa ttatttcgaa gaacagctcg gtggatgtac gatcgaaggg catagattcg
    61201 agattttcgg aagatgtgaa aattgtcaat aaggatttaa ataaaataac atttgataat
    61261 tttaaaaaaa agcaagattt ccttgacggt caaaacagca ttagatataa tatttacagg
    61321 acagtcttgt tttttgagat atatttcaat aacaattacg gttacttttt aagctcggag
    61381 ggagggaatt aacatgtcaa aaacagtcgt tcgcaaaaac gaatcacttg acgatgctct
    61441 tcgtcgcttc aaacgttccg tgtcaaaagc gggtacttta caagaatctc gtaaacgtga
    61501 attctacgaa aaaccaagtg taagacgcaa gaaaaaatct gaagcagcta gaaaacgcaa
    61561 aaaattctag ttctgtgatg aattggagtt ggtagtgtgt cactactaag tagattaaac
    61621 gatgacatga aaacagcgat gaaagcgaaa gataaggaat ctttacaagt catccgaatg
    61681 atcaagtcat ctatacaaaa cgagcagatt aaagaaggtc acgacttgac agaagaagaa
    61741 gaattaacgg tgttgtctcg cgaaatgaaa cagcgacgtg attctttgca tgagtttgaa
    61801 gaagcaggac gtgacgattt agctgaaaaa gtaaaaagtg aaattgtgat agtcgaaaaa
    61861 tacatgccgg aacaactttc cgacgaagaa attcgacaac ttgttcaaga agcaatcaca
    61921 caaactggtg cttcatcaat gaaagaattt ggcaaagtca tgggtgcgat catgcctaaa
    61981 gtcaaaggaa aagcagatgg aaaccaagta aatgccattg tgaaagaact attacaatct
    62041 taattttatc atttaaactg cggacaatca ttgtccgcag tttttttgtg cgcgtaaaaa
    62101 agagaacaaa aaaatagcta gacgaaagaa taggattctt tcatctagct ggttttttcc
    62161 tgtttaatat ttcttatgtt aaattgtgtt tgatttggtt attcttctgg tagttcattt
    62221 gcttcttgtt tataccctga taggcgatag gcgtaataaa acagtaggct gccagcgtaa
    62281 ccaagtaacg ttgggaccat ccagccaagt cctaatgcag caaaaggaac gtgatgatga
    62341 taaaattcga gcatgcttgc tacaactctt tgttgactca ctaaagcagg cgaatttgcc
    62401 agcatatcca atacggcagg aacagcagca aacaacatcg ttacttgata gacaaatggt
    62461 gtcttttgga aaaattttgc tgttaaggaa agcaagatca acgcaagcga caatggatac
    62521 aaaagcatca atactggtaa agaccattgg atgatattgt ctaaaccagc atttgcaacg
    62581 acaaaagaga cgaaagtcgt taaccgcagc catgtcatat aactgacttt agggaacagt
    62641 ttatggaaat cttgcgcaaa agaaacaacg agtcccatag cggtagtgaa gacacctaat
    62701 gtgaccatca ctcctaagaa gctagcgccg aagttaccta aataaaaatt agtgatctga
    62761 gaaagtgcag ttccgccatt ttctgataaa gacatcttat tcaaactcat cgcaccgaga
    62821 agaacaagac caaaatagat catgacttct agcgcaacgc tcaggctacc agcttttgct
    62881 gttaattctg tgactttttt atctttgaaa ccaaggtcac ggactgcatg gacaaaagtg
    62941 acacttaagg caagcaaggc tactgcatca accgtgttat aaccttctag gacaccattt
    63001 gttaaagcgt ttgtttggta agtatctgca gcagattgat ttagatttcc cattgggtgg
    63061 aataaagaaa cgacaaaaat gattgctaac aatgcaagaa acaaggagtt tagatacttt
    63121 ccgacgtatt tgaccaaccg tgtgggatgg acagtaagga aataagcaag taaaaagaaa
    63181 agagcagaga ataaaaacat acctaatgaa ttatattttt caggcaaaaa tggtttagca
    63241 gccatttcaa aagcagtagc agctgtccgt ggtgtaccga aaaatggtcc gatcgtcaaa
    63301 tgaacaagga ttaagaacaa ggcagcatac cattttccga caggtttagc taagtcatac
    63361 agaccatcac tttttgtcac tactacagct aagatagcta gtaatgggaa aagagcgccc
    63421 gagatggcaa atcctacgcc agcactgacc cagtttgcgc cagccatttg acctaagtgg
    63481 acaggaaaga ttagattacc tgacccgaag aacatcccga agataagtga actgaccatc
    63541 aatagttgtt tccatgaata agtttttgtt tcttccataa atttttcctc caataattat
    63601 cattttgatt gacgatataa acgttgcagc aattagtaat gccactaata tcagattcca
    63661 tgaaaaccac caccttaaaa tataaaaaaa gcccttttcc acttgggaaa agggctctag
    63721 attctagaac ggtaccacct tttttcgctt aaaaaagctt cttcattcac ggacgctttt
    63781 tgataaagtt atccgctagc ctgataatgg aggcagccac aatgatctac gttttcgaca
    63841 ttgactcgga aatgatgttc gtctattcga tttattgtca tttctcactt acatgactca
    63901 ctgggaataa atcgttgaat agcctactgt tttcctcgac gctttgctgt atgtttattt
    63961 gttgacgtaa taatacacct gttttttttg aaatgcaaga atattttaac tattttgttt
    64021 tctttttttg aaacaagaaa aatacctaga gaatacctgc tgaatgaaac ggaatatttt
    64081 gttctccact ttcatataac ttacattctc agcttctttt tatcaaaacg agacctttag
    64141 cgaatggaaa cggctatttt ttaacgtttc ttggtacgta tggttaaacg actcttttac
    64201 aaccttttct tatttgctat atagtttctt ctgagtatgg taaaatagga aagaatgaat
    64261 cgaaaaaaag gggatgtcta tttttgacgg aagagtctag ttctttagag attagattga
    64321 cagctgctga tgatgtcagc atgcttttag gtgcacacga caagcatata aaactgatcg
    64381 aggaaacaac ggaaacaacc atccatacac gtggagaaat cattcagatc attggtgagc
    64441 aatcccagat ttccttggct gcctcagtca ttcggacatt acaggaattg atcaaacgag
    64501 gaatccacgt aagtacgcca gatgttgtga cggcattgaa gatggggcaa aaaggtacat
    64561 tagattattt tgttgagatg tatgaggaag agatcgtcaa agaccgtaat ggaaaaccta
    64621 tacgggtaaa aaacagcggt caaaagaaat acgttgaatc ggtagccaaa catgacatcg
    64681 tatttggtgt agggccagcc ggaacaggga aaacgtttct tgccgtagta ttagcaattg
    64741 ctgccctaaa aaaaggcgaa gtgcaaaaaa tcattttgac gcggcccgct gtggaggcag
    64801 gggaaaacct aggctttcta cccggggatc tgaaagaaaa agtggatcct tatctgcggc
    64861 ctgtttatga tgctttatac caaatttttg gattggatca tacgaaccga ttgatggaac
    64921 gaggcgtgat cgaaatcgca cctttagctt acatgcgggg gcggacattg gatgatgcat
    64981 tcgttatctt ggacgaagca caaaacacga cagtcgctca gatgaaaatg ttcttgaccc
    65041 gtctcggtta tcaatcaaaa atgattgtca atggggatac aagtcagata gacttgcctc
    65101 gtgggacgac aagtggtctt gttcatgcag aacgaacatt aaagcaaatc aaaaaaatcg
    65161 attttgttaa ttttgaagca agtgacgttg ttcggcaccc tgtagttgcc gaaatcatca
    65221 aagcttatga aaaggcggat cttcatcaag aataagcttt gcttaggagg ataagcacat
    65281 gttgaataaa acactgcaga aactacaaaa aaaactcgga aaggcagcat tgcctttcct
    65341 tctgttcttg ttttttatca ttgtctgcgg cgttacattt agtagtgtca aacaaaaggc
    65401 caatgatttc agagaaggcc aagtagcaga agagagtatc cgtgcgaata aaacgattga
    65461 gaacacggaa gaaaccgaac aaagaagaaa actggcagca gaagcagtga ctccagaata
    65521 tacttatcaa aaagatctgg cagatgacca gaacaatcgg atcaagcaat tattcgaatt
    65581 gatcgataag acgaatgata ccatcaacaa atcttataat gacaaggtag ataaggcgaa
    65641 ggaagatgaa aatatcccga aacctactac agaagagcgg attgctacac tgaagaaaaa
    65701 ttttgaaaac gtgaatgcag aaaacgttgc gttttaccaa aaactgccga acaattttta
    65761 ttcgacgata tttgaaatga ctgaaacgga aattcacacg gttagggatg aaagtttgaa
    65821 gctcattgac gaacagatga gtaaacaagt tcgtgaaagc gaattggaag cttttaaaca
    65881 agaagcagaa gatcagattc aatatttgaa tgtcacaaca gagcagcaac aaatgattcg
    65941 ctacttagtg gatcaaggca ttgtagttaa tgatgtattg aatgagaaaa agacagaaga
    66001 attaaaacaa tctgcacgag aagctgtaca accagtgatg atcttccaag gagaaattat
    66061 tgttcgcgaa ggaaatcaaa ttgatgcttc agcgatgaaa aaattggaat tactaggatt
    66121 gacgaatcaa acgacttcta ttttcccact cattgccatg gttttagctg ttttgcttca
    66181 aatcggtgta ctgatttata attcacttca attccaaaat gcaggagaaa gaacaaaata
    66241 cgtacttttc tacgtgacgg caatgtcagt aagcgtcgta ctaatgaaat ttttccaact
    66301 cttccaaaca gaacaagctg cttatattcc gctgttttac cccgcggctt ttgctccact
    66361 tgttttaagc tttttcttga atcgaagagc agggatcatg gctggtattt ttcaagcagt
    66421 atccgcactt ttcatttttt atgattcgat tggcacgaac tttctgacag ttattttgat
    66481 gtcctatgta ttttctggtc tcatggcaac gatcgtcaga cgcaaacgga tctcagaaca
    66541 agggttatcc gctgctatgt gggtcattat ttttcctgtg atgatggatg tcattttgat
    66601 tatctaccaa ggaatgagct ttggggatgc aacgacttgg ttaacgctag tatgcggatt
    66661 cacaggtgca ctgttctcat tcttgctgac gataggtctg cacccctata ttgaattgat
    66721 ggtcaatgat gatagtgtga tcgtattaaa tgaactcagc aatcctaatc atcctttatt
    66781 gaaacagttg ctggaagaag caccaggcac gtatcaccat agcatgatgg tagccaatct
    66841 aagtgctaat gctgtagcag aaatcggtgg acgttcttta ctaactcgag tagcttgcta
    66901 ttatcatgat atcggcaaga tcaaacacgc cagctttttc gttgagaact tgccttcagg
    66961 agcggaaaat ccgcacaatt tcttattgcc agaagacagt aaacatatta tctttggaca
    67021 tgtgacagat ggtgccaaaa tattggaaga ttataatatg ccgcaaatgg tgatcgatat
    67081 ttgcagacag catcatggaa ccacgctgat gcgttatttc tacgttaagg caaaggaacg
    67141 caacccggaa gtcacggaag agcaattccg ttatcctgga ccaaaacctc aaagccgtga
    67201 agcaggaatc gtcaatatag ctgacagttg tgaagcggca gtacgagcaa tggaccatcc
    67261 aacgagcgaa aaaatcgaaa gttttgtcca taatcttatt gaagagcgta tttccgatgg
    67321 acaattggac gacagtggat tgacgttaaa agaaatccgt aaagtagaaa aatcattgat
    67381 cagcggttta agcagtacct tccattctcg gatcaaatat cctaaaatga aatcggaagt
    67441 tgagaagata aaagaagaac aagaagaata gaaagaagcg atgtataatg gatattactt
    67501 tcatggatga aacaaaccaa gtctcagaag agaaaatgaa agaaatcgac gacttgctgc
    67561 aatttgcagc atcatattta gagttgccag aagaaacaga aatgtctgtt actttcatgg
    67621 acaatgcagc gatccaagta atcaatcgtg attaccgtgg aaaagatgca ccgacagacg
    67681 tcatcagttt tgccttggaa gaagagggcg aagacgaaat cccagtgatt tttgaagatg
    67741 gagagaatcc attgcctcgt gtactgggag acatcatgat ctctactgaa cgtgctgcag
    67801 agcaagcaga agcttacggc cattcgtatg atcgggaact tggcttttta gcggttcatg
    67861 gattcttgca tatcaacggg tatgaccata tgacaccaga ggatgagaaa gaaatgtttg
    67921 gtttacagaa agagatctta gatgcctatg gacttaaaag ataaaaacgt agagaaaaac
    67981 aaacatttcc tgatgtccgt ggaatttgcc gtccaaggag tcaaaaccgt ttttgaggaa
    68041 gaacgcaaca tgaggaaaca tgttgcgttc ggaatcctcg ctttgtttat gggcgtgatt
    68101 ttccagcttg atcggataga atggttatgg ctgcttttag ctgtttttct cgtatggata
    68161 gtagagatca tcaatactgt ttttgaaaat gtcgtggaca tgtttacgga ttttcatttt
    68221 catccgattg ggaaaaaaat caaagatatg gcagctggag cagttttagt gaccgcttgt
    68281 ttttccgtca tcgttgggtt gattttattt gtccctaaaa tatatcattt gttgtttaat
    68341 taaaaaggag aacgtatatg ccagaacata aatcagggtt tgtcgcaatc gtcggccgcc
    68401 cgaatgtagg aaaatccaca ttattgaatc gaatcgtggg tcaaaaaatt gccatcatga
    68461 gtgataaggc gcagacaact agaaataaaa tccaaggagt atatactaca ccagaagctc
    68521 agttgatttt tattgacaca ccaggaatcc ataaaccaaa gcatcgttta ggagatttta
    68581 tggtagaagc agcttacagt gcgttgaaag aagtggacgc ggtcttattt atgatcagcg
    68641 ctgatcaaaa acgcggtcgg ggagacgatt ttattattga acgtctaaaa aacgtgcatt
    68701 ctcctgttta tctgattatc aataaaatcg ataaaatcca tccagacgag ttgttgggaa
    68761 tcatcgaaga ttattcaacg cagatgccgt ttgcacaagt gattccaatt tctgctacag
    68821 aaggaaacaa cgtcgaacgt ttgatggatg tattagtcag tgaaatgcca gagggcccac
    68881 aatattttcc agatgatcaa gtgactgatc atcctgaata cttcatcgtt tctgaattga
    68941 tccgtgagaa agtcttgttt ttaacacgag acgaagtgcc tcattctgtc gcagtcgttg
    69001 ttgattcgat gaagcgaaac gagaatgata aaatccatat ccaggctacg attattgtcg
    69061 aaagagatag ccaaaaaggg atcattatcg gcaaaggcgg aaaaatgctg aagcaagtag
    69121 gaacgaaagc gagaaaagat atcgaaaatc ttttaggaga caaagtcttt ctagaacttt
    69181 gggtcaaagt tcaaaaagac tggcgagaca aaaaagtcta tctgcaagac ttcggctacc
    69241 gaaaagacga atattgatat tctgagcttc ttgtaagtta ggtatagaaa taaactggat
    69301 aaaaatccgc gtgttgagaa aagctgcgga agatcgcaac ataaatgatc tggatcggca
    69361 gaatctgctt ttccagattt attttttagg agggagaata tgagccagct tgcagaatca
    69421 aaaggcttga ttttatctag ccgtaattac aaagaaaaag ataaattagt caaaatcttt
    69481 acggaatctt ctggcaaaat gatgttttat atcaaaggga tccatcggca aaatcagccc
    69541 ttagctccgg ctttgctccc ttttactgaa gcagtttata tcgggaattt tcgaagtgaa
    69601 ggtttgtcat ttttaagcag tgtcaaagat gtccacgcgt ttcgacacat ccaagaagac
    69661 atctttttga gcggctatgg cacatattta ttgaatctag tagatgcggc aatcgaagat
    69721 catcagtacg acccgcattt gttccagttt acgcaacaag cactgcaacg gatggaccaa
    69781 ggagatgatg cagaaatcat cacgaatatt tttgaagtcc aaatactgca acgcttcgga
    69841 attgcaccaa tctggacaca ctgcgtcgta tgtggggaaa caaaaggaaa atttgactat
    69901 tcttccaaat atggtggtgt gatatgcgaa agacactggt cgatggatga tcaccgttat
    69961 catgcagatc ctcgagctgt ttatttcgtt cggatgtttt cagctatttc ttatgataaa
    70021 atcagtggaa tccatctgaa agaagaaacc aaacaagcaa tccgtgaact catcgaccag
    70081 ctgtatgatg aatatgtcgg tatccatttg aaaagcaaaa agttcattga tcaaatgaag
    70141 tcttgggcac acgtattaaa gacgtcagag aaagacatgt ctgaaaaaga tctacctaaa
    70201 aaagaagaat agtaaatgaa acatacaaca aaaaatcaaa accatttgac aaacacaggg
    70261 agttccgtct attattaacc gtagatcaaa tagatcgttc actgagagga tctattatag
    70321 aaacaagaaa actgcaaaat gaatacgtac attgaccaag atcagtaaaa aacacgtggt
    70381 ttagcgagtt cgggagagtg ggagccggac ccaaacgatt tttgaagagg cacttgcgag
    70441 tacgataaat gaagctgccg aatctttatt cggaagtagg gtggaaccgc gaattattcg
    70501 tccctatgtc tgtaatcaga catagggatt ttttgtcgtt ttctttcctg tattcttatt
    70561 tgacagcaac gctttaaaat tgaaaggggc aaaacagatg agtaaaaaat tgaccgtcca
    70621 agatatgatt ttaacattac aaaaattttg gtcatcaaac ggctgcatgc tgatgcaagc
    70681 gtatgacaca gaaaaaggag caggtacgat gagcccatat acctttttac gggcaatcgg
    70741 accagaacca tggaatgctg cttacgtaga gccatctcgc cgaccagctg atggacgtta
    70801 tggcgaaaac ccaaaccgtt tgtatcagca tcatcaattc caagtcgtga tgaaaccttc
    70861 acctgagaat atccaagagc tttatttaga aagcttgcgc cttttaggaa tcgatccact
    70921 agaacacgac atccgttttg ttgaagacaa ctgggagaac ccatccatgg gctgtgccgg
    70981 tgtgggttgg gaagtatggc ttgacggaat ggaaatcaca caattcacgt acttccaaca
    71041 agttggtgga ctgccttgta aaccagtaac ttctgagatc acttatggat tagaacgtct
    71101 tgcttcttat atccaagaag ttgaaagtgt ctatgattta gaatgggctg atggcgtgaa
    71161 atatggcgag atcttcaaac aaccagaata tgaacattct aaatattctt ttgaagtaag
    71221 cgaccaagac ttgctactaa gcaactttga tcgttttgaa aaagaagcta aacgctgtat
    71281 cgatgaaaat cttgttcatc cggcgtatga ttatatcttg aaatgtagcc atacattcaa
    71341 cttattagac gcccgcggtg cagtatccgt aacagagcgt gccggttatc tttctcgcat
    71401 ccgcaacatg gctcgtgctg tagccaaaat ctttgtggca gaacgcgaaa aattaggatt
    71461 ccctttgttg aataaaaaca cagcaaatcc agaaaacgtg aaggaggctg aataagatgg
    71521 caaaagactt attacttgaa atcgggctgg aagaaatgcc tgctcatgtt gtcacaccaa
    71581 gcatgaaaca attagaagaa aaaacagcaa aatttttaga tgaaaaccaa ttgacttatg
    71641 atacgatcga aacattttcc acaccgcgcc gtttagcaat caaagtaaca aacattccag
    71701 aacgacaagc ggacagtgaa gaagaagtca aaggaccagc caaaaaaatt gctttggacg
    71761 cagatggaaa ctggacgaaa gcagcggaag gatttgtccg cggacaaggt ctgacgacag
    71821 acgctatcac ttttagagaa ttaaaaggtg tggaatatgt ctatgtaacg aaatacactc
    71881 atggtaagga atccaaagaa gtattgacag gtttagcaga tgtcattaaa agcctgactt
    71941 tccctgtaac gatgcattgg gcagaatacg attttgaata tatccgccct attcactgga
    72001 tcgtggcatt gttagatgac gaagtaatcc cattcgaaat cttggatgtc aaaacaggca
    72061 gagcctctcg aggtcatcgt ttcttaggcg aagatgtgac atttgcgcat gcaaaagaat
    72121 atgaagaaaa attgaatgaa caattcgtca ttgcgtctcc gcaaaaaaga caagaaatga
    72181 tcgttacaca agccaatgaa ttagccgaaa aaaatcattg ggttattgat ctagacgaag
    72241 atttactaga agaagtcaac aatttagtcg aatatccaac tgtcttttct ggcgacttcg
    72301 aagaaaaata tctttctgtt cctgaagaag tactagtcac ttctatgaaa gaacatcaac
    72361 gttatttcga ggtacggaat gatcaaggta tgctgcttcc tcattttatt tctgctcgta
    72421 atggtgatcg ggtaaaattg gaaaatgtgg ttcgaggcaa tcaaaaagta ttgacggctc
    72481 gtttagaaga tgcggaattc ttttataatg aagacaagaa agcttcaatc gaccaatacg
    72541 ttgaaaaact aaaaactgtt actttccatg aaaaaatcgg tagtatctat gagaaaatgc
    72601 aacgggtaca agtcattgcc cgtatcattg gcgaacaagt aggactatct gaggaagaat
    72661 tgatggatct gcaacgagct gctgaaatct ataaatttga tctagtaacc aacatggtag
    72721 gggaatttcc tgaactgcaa gggatcatgg gcgaaaaata tgctctgctg aaaggcgaga
    72781 aacctgctgt agcgacagcg attcgtgagc attacatgcc tatatccagt gaaggagagc
    72841 tacctcagtc tacagtaggt tctgttttag cgattgcaga taaattagat agcatctttt
    72901 ctttctttgc tgttgggatg atcccaagcg gttcaaacga tccttatgcc ttacgtcgcc
    72961 aagcatacgg tgtcgttcgg atcatcgaat cgaaaaaatg ggcctttcct ttgtctgttc
    73021 tgcaagaaac gattagcgat gttatcagta aagatacgga tcgtttcggc attggtttat
    73081 cagaagggca acaacaagtg atcgacttta tcaaaggccg tctgcgccaa ttattgacaa
    73141 cgaagaatat tcgtcatgat gtcatcgatg ctgttttgaa tgcggaacaa aaagatctga
    73201 caaaagtatt tgcagcagca caattgttca aacaacatct tgcagatgaa gacttcaaac
    73261 cttcaatgga agctttgaca cgtgtcgtga acttagcgaa aaaagcgcag cttgaaaaac
    73321 aatcagaagt agatcctgag ctgttcgaaa acgacgcaga gaaagaatta cacaaagcag
    73381 tagaagcaat gaaagcaagt tttgctgacc aaacgatcca cgaaaactac gaccagcttg
    73441 tcgctcttcg tccactgatc gaaaattatt ttgatcaaac gatggtcatg gctgatgaac
    73501 cagcagtacg taagaaccga ctaacacaac ttagtcaaat agctgccatg gctttgtcat
    73561 tagcaagctt ggatcaaatc atcacaaaat agtcttttgt ttgaaaaaca gagagcatgc
    73621 acgaaacgtg ctgtgtctct gtttttttgt tataaat
//
LOCUS       DADVXM010000007        65985 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.007, whole genome shotgun sequence.
ACCESSION   DADVXM010000007 DADVXM010000000
VERSION     DADVXM010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 65985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.007"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            213..1427
                     /locus_tag="KB927_000533"
     CDS             213..1427
                     /locus_tag="KB927_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBB6839476.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            1458..2885
                     /locus_tag="KB927_000534"
     CDS             1458..2885
                     /locus_tag="KB927_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6839477.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            2908..3834
                     /gene="glsA"
                     /locus_tag="KB927_000535"
     CDS             2908..3834
                     /gene="glsA"
                     /locus_tag="KB927_000535"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBB6839478.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            4042..5502
                     /locus_tag="KB927_000536"
     CDS             4042..5502
                     /locus_tag="KB927_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839479.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            5723..7486
                     /locus_tag="KB927_000537"
     CDS             5723..7486
                     /locus_tag="KB927_000537"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBB6839480.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            7570..8028
                     /locus_tag="KB927_000538"
     CDS             7570..8028
                     /locus_tag="KB927_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBB6839481.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            8137..8820
                     /locus_tag="KB927_000539"
     CDS             8137..8820
                     /locus_tag="KB927_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBB6839482.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            8967..9581
                     /locus_tag="KB927_000540"
     CDS             8967..9581
                     /locus_tag="KB927_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBB6839483.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            9597..9803
                     /locus_tag="KB927_000541"
     CDS             9597..9803
                     /locus_tag="KB927_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839484.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            10342..10899
                     /locus_tag="KB927_000542"
                     /pseudo
     CDS             10342..10899
                     /locus_tag="KB927_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            10957..12996
                     /locus_tag="KB927_000543"
     CDS             10957..12996
                     /locus_tag="KB927_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBB6839485.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(13105..14256)
                     /locus_tag="KB927_000544"
     CDS             complement(13105..14256)
                     /locus_tag="KB927_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBB6839486.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(14410..14940)
                     /locus_tag="KB927_000545"
     CDS             complement(14410..14940)
                     /locus_tag="KB927_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBB6839487.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(15039..15389)
                     /locus_tag="KB927_000546"
     CDS             complement(15039..15389)
                     /locus_tag="KB927_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBB6839488.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(15546..17075)
                     /gene="ahpF"
                     /locus_tag="KB927_000547"
     CDS             complement(15546..17075)
                     /gene="ahpF"
                     /locus_tag="KB927_000547"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBB6839489.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     RTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(17085..17648)
                     /gene="ahpC"
                     /locus_tag="KB927_000548"
     CDS             complement(17085..17648)
                     /gene="ahpC"
                     /locus_tag="KB927_000548"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBB6839490.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(17792..18454)
                     /locus_tag="KB927_000549"
     CDS             complement(17792..18454)
                     /locus_tag="KB927_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6839491.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            18638..20284
                     /locus_tag="KB927_000550"
     CDS             18638..20284
                     /locus_tag="KB927_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBB6839492.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            20275..21357
                     /gene="uxuA"
                     /locus_tag="KB927_000551"
     CDS             20275..21357
                     /gene="uxuA"
                     /locus_tag="KB927_000551"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6839493.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(21465..23018)
                     /locus_tag="KB927_000552"
                     /pseudo
     CDS             complement(21465..23018)
                     /locus_tag="KB927_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            23166..24454
                     /locus_tag="KB927_000553"
                     /pseudo
     CDS             23166..24454
                     /locus_tag="KB927_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(24580..25659)
                     /locus_tag="KB927_000554"
     CDS             complement(24580..25659)
                     /locus_tag="KB927_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6839494.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(25762..26202)
                     /locus_tag="KB927_000555"
     CDS             complement(25762..26202)
                     /locus_tag="KB927_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6839495.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(26259..26669)
                     /locus_tag="KB927_000556"
     CDS             complement(26259..26669)
                     /locus_tag="KB927_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBB6839496.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(26849..27283)
                     /locus_tag="KB927_000557"
     CDS             complement(26849..27283)
                     /locus_tag="KB927_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6839497.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(27383..28231)
                     /locus_tag="KB927_000558"
     CDS             complement(27383..28231)
                     /locus_tag="KB927_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6839498.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            28620..30386
                     /locus_tag="KB927_000559"
     CDS             28620..30386
                     /locus_tag="KB927_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBB6839499.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            30488..31747
                     /locus_tag="KB927_000560"
     CDS             30488..31747
                     /locus_tag="KB927_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6839500.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            31894..33195
                     /locus_tag="KB927_000561"
     CDS             31894..33195
                     /locus_tag="KB927_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6839501.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            33198..34049
                     /locus_tag="KB927_000562"
     CDS             33198..34049
                     /locus_tag="KB927_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6839502.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            34062..34877
                     /locus_tag="KB927_000563"
     CDS             34062..34877
                     /locus_tag="KB927_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBB6839503.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            35028..36194
                     /locus_tag="KB927_000564"
     CDS             35028..36194
                     /locus_tag="KB927_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6839504.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            36424..37071
                     /locus_tag="KB927_000565"
     CDS             36424..37071
                     /locus_tag="KB927_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBB6839505.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            37155..38099
                     /locus_tag="KB927_000566"
     CDS             37155..38099
                     /locus_tag="KB927_000566"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBB6839506.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            38234..39685
                     /locus_tag="KB927_000567"
     CDS             38234..39685
                     /locus_tag="KB927_000567"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBB6839507.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            39706..40542
                     /locus_tag="KB927_000568"
     CDS             39706..40542
                     /locus_tag="KB927_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBB6839508.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            40542..41201
                     /locus_tag="KB927_000569"
     CDS             40542..41201
                     /locus_tag="KB927_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6839509.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            41327..42016
                     /locus_tag="KB927_000570"
     CDS             41327..42016
                     /locus_tag="KB927_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839510.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            42022..42978
                     /locus_tag="KB927_000571"
     CDS             42022..42978
                     /locus_tag="KB927_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBB6839511.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            43022..43534
                     /locus_tag="KB927_000572"
     CDS             43022..43534
                     /locus_tag="KB927_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6839512.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(43790..44338)
                     /locus_tag="KB927_000573"
     CDS             complement(43790..44338)
                     /locus_tag="KB927_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6839513.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(44427..45608)
                     /locus_tag="KB927_000574"
     CDS             complement(44427..45608)
                     /locus_tag="KB927_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBB6839514.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(45844..47352)
                     /locus_tag="KB927_000575"
     CDS             complement(45844..47352)
                     /locus_tag="KB927_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBB6839515.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            47511..47702
                     /locus_tag="KB927_000576"
     CDS             47511..47702
                     /locus_tag="KB927_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839516.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            47905..48822
                     /locus_tag="KB927_000577"
     CDS             47905..48822
                     /locus_tag="KB927_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBB6839517.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            48815..49888
                     /locus_tag="KB927_000578"
     CDS             48815..49888
                     /locus_tag="KB927_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839518.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            50036..50554
                     /locus_tag="KB927_000579"
     CDS             50036..50554
                     /locus_tag="KB927_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839519.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            50535..50927
                     /locus_tag="KB927_000580"
     CDS             50535..50927
                     /locus_tag="KB927_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBB6839520.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            51003..51938
                     /locus_tag="KB927_000581"
     CDS             51003..51938
                     /locus_tag="KB927_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBB6839521.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            52071..52850
                     /locus_tag="KB927_000582"
     CDS             52071..52850
                     /locus_tag="KB927_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBB6839522.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            52843..53160
                     /locus_tag="KB927_000583"
     CDS             52843..53160
                     /locus_tag="KB927_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBB6839523.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            53404..55014
                     /locus_tag="KB927_000584"
     CDS             53404..55014
                     /locus_tag="KB927_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6839524.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            55171..56019
                     /locus_tag="KB927_000585"
     CDS             55171..56019
                     /locus_tag="KB927_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6839525.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            56250..56729
                     /locus_tag="KB927_000586"
     CDS             56250..56729
                     /locus_tag="KB927_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839526.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            56762..58990
                     /locus_tag="KB927_000587"
     CDS             56762..58990
                     /locus_tag="KB927_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6839527.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            59119..60762
                     /locus_tag="KB927_000588"
     CDS             59119..60762
                     /locus_tag="KB927_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBB6839528.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(60835..61380)
                     /locus_tag="KB927_000589"
     CDS             complement(60835..61380)
                     /locus_tag="KB927_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBB6839529.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(61403..61888)
                     /locus_tag="KB927_000590"
     CDS             complement(61403..61888)
                     /locus_tag="KB927_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6839530.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(61878..62690)
                     /locus_tag="KB927_000591"
     CDS             complement(61878..62690)
                     /locus_tag="KB927_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBB6839531.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(62829..64361)
                     /locus_tag="KB927_000592"
     CDS             complement(62829..64361)
                     /locus_tag="KB927_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBB6839532.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            complement(64470..65501)
                     /locus_tag="KB927_000593"
     CDS             complement(64470..65501)
                     /locus_tag="KB927_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6839533.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT        21901 a        11789 c        12839 g        19456 t
ORIGIN      
        1 aataaaaaaa gacgaaaata aacggttttc tataaaaaga agaccgttta ttttttgtct
       61 ttatttgtgt gaaaaacgaa aaagagcaca acacatcaag cttttattaa ttgtctgtct
      121 tttataaatg caagtattaa ttcaaaaaaa cagaagaaaa aaacaactac accttctttt
      181 atactcgtaa tcgtagaaag gaggcgaaaa aaatgaatac attacctatc aatacaggag
      241 atacagcatt catgatttta tgtacagcaa tggtttgcct gatgactcct ggtctagctt
      301 ttttttacgg cggattagca cggaagaata atatactaac gatcatgtct caatcttttc
      361 tctccgttgg gataacaacg attatgtggg tatttggtgg attcggattg gcctttggac
      421 gggatatcgg cggtgttatt ggaaacccgg cagatttctt tttgatgaga catgttacaa
      481 gcttccccaa catgtttcat ggtgcaacga ttccattttt aatgttcttt ctttaccaac
      541 tgatgtttat cgtgattacc gttcctttga tgacaggagc ttttgcaggg agattgaatt
      601 taaaaggcta tattatactt gttatttttt ggaatctgct gatttatttc cctgtttgcc
      661 actggatatg gggtggcgga tttttggatc agatgggatt tagagatttc gctggtggag
      721 cagtcatcca cacgacagct ggattcggct ctttagcatg tatcctcaca cttggtcaaa
      781 gaaagattcc tttaggagaa agaagtcagc atagcagtct tatggcagct gctatcggta
      841 caggactgct ttggtttggc tggttcggtt ttaattccgg tggtgcactt cgagcagatg
      901 aacaagcagt caatgcattt ggttcaacat tcatcgctct tgcatttgcg atgattactt
      961 ggctgatcat tgcaaaagta aaaggaaatg gctttgattt tgtcgacgta ctaacaggat
     1021 ccgttgctgg attggcagcc attacgcctt gtgccggtta tgtagaagca aaaagtgcca
     1081 tgctgattgg gatcattgcg ggtatcgtct gtcatgctgc tgttgatttt cgtaaaaaga
     1141 aacaatggga tgatgcactt gatgtgtggg gtgttcatgg catgggcgga ttcacaggta
     1201 cgattctgat agggatcttt gcatctaaca gccatttact aacgaatcca agcagctggt
     1261 acttcttagg gattcaagtg attggtgtca tcattactgc cgtgtatgcc tatgtgctga
     1321 caacagtgat tttaaaatcg gcgatgcact ttacaacgat cactactaca aaagaagaac
     1381 aagaagaagg attggacttt ttcttctttg gcaacaaact caattgaaac aaattcaaat
     1441 agaaaagagg aagattcatg caacaaagca aaacgaaaat tcctgcaaaa aaattaacgt
     1501 tctttggctt tttggctatg accatctcaa tggtcgtttc attatatgaa tatcccacat
     1561 tcgcgacctc aggcttcagc ttagtatttt tcttgttatt aggcggtttg ctatggttta
     1621 tccctgtggc attgtgcgca gcagagatgg caacggtgaa aggatgggaa aaaggcggtg
     1681 tctatacttg ggtcagtcgc acattgggaa aacgattcgg ttttgccgca atctttttcc
     1741 aatggtttga gataacagtt ggctacttga ccatgctgta tttcttaact ggtgcattat
     1801 cctatgcaac gggtattggt gctatacaaa acaataaata tctgaaattg gcaatcctat
     1861 tgattatttt ctgggctatt ttactctcac agttaaaagg aaccaaatac acttcattga
     1921 ttgctcggat cggttttgta gctggtatct tgttgccagc attagtcttg tttggcttag
     1981 ggatccatta tgtcgcttca ggcgctccac tacaaacgat actgtctatg aaaacattga
     2041 ttcctgattt ttcgaaattg cctacgctgg ttgtttttgt ttcctttatt ttagcatata
     2101 tgggcgtaga aacatctgcc agtcatgcaa atgaaatgga aaaccctaaa aaggattatc
     2161 cattagcaat gtttgtattg gttattctgg caatcatttt agatactttt ggcggattga
     2221 ccgtcgctac tacagtacct caacatggtt tgtctcttaa tacaggggtg attcaatcgt
     2281 tagaattcct attaagacac attgatccaa atcttgcatg gattgcgaaa attcttgcga
     2341 ttcttgtttg tttaggtgtc atcggagaaa ttgcttcttg ggtaacctct ccttcaaaag
     2401 cacttcacgt agcagcagaa gaaggattac ttcctgaata ttttgcaaaa gaaaacacac
     2461 acggtgttcc tgctcatttg atgatcgcaa atgggatcgt tgcaacaatc tgggcagccg
     2521 tctttacatt aagcggcggg gggaataatc tttcatttct tgcagcgatg tcattgactg
     2581 ttgtaatcta cctgatgttg tactttatgt ttttcgcggg ctatttgaag ctggttttta
     2641 aagatgacag tcttgaaaga gcctatcagg ttccaggcgg aaaagttgta aaagtaatcg
     2701 ttgcttgttt aggtcttttg acttcacttt ttgctttttg tatctcattt gttccacctg
     2761 ctagtatcgc agctggacag catgggattt atgaaacgat tctgattgtt tcttatctta
     2821 tcgtcttagt tattccattt acgatctacg catgccgtca taaattccag catgcagaaa
     2881 aataaaaaat gaaagctggt tattcaaatg gaagtaaaag aattagaaca attgattgga
     2941 aaaaatttcc actattatca aacaggacaa gtggcggatt acattccagc attagctgaa
     3001 gtggatccca aacaattagg tatggcgatt tatgatttgg atacaaaaca actgattgag
     3061 ggaggagacg ccgatgtgcg ctttgccatc gaaagcatgt caaaagttcc cgtattgtta
     3121 ttagcaatca aagacaacgg aatagaaaaa gtctttcaaa caatcaacac ggaaccaacc
     3181 ggttttgcct tcaattctat catgaatatg gaaatcaatc atcgcaaaca tccaatgaat
     3241 ccttttgtta atgcaggagc gattgcaaca acctcgttga ttgccggtaa agatgcagat
     3301 gaaaaatttg agcgaatctt gtcatttatg aaagagatct gtgatgatcc taatatcaca
     3361 ttgaatgaag aaatctatca ttctgaatca agaacaggtg atatcaatcg ctctcttgct
     3421 tactatatga aaggtaatca aatgatcgaa ggagacgtac cggagatact cgatgcttat
     3481 ttcagacaat gctccctcaa tgtcaccgct acaggcatag caaaattagc tgctgtgctg
     3541 gcaaataaag gaattgctcc ttggaatggc aaacaaatca ttactgaaga aagtgctaca
     3601 atcgtcaaat caattatgac aactgctggt ttgtatgatg aatcaggaga gttttccgtc
     3661 catgttggtg tacctgcaaa aagcggtgta ggcggcgggt tgatggcagc tgtgccaaat
     3721 cgttacggca taggtgtctt cagcccggca ctagatccat ttggtaacag cgcagctggt
     3781 atccaattgt tgaaagatgt agtcaaagaa ctagacgctg acatctttga ataaccattc
     3841 ttgaaagagg ctggggtaaa agtccaaacg gctcaaagct acctacaatg aggctgaaat
     3901 tgtgagcttg tttgactttt gtcccagttt ctttttttat tggtttttga aagggctttt
     3961 ctaaataaaa aggaaacaaa aatacgattt acagatatga ttaaataaaa tcataagaaa
     4021 aactggaggc gtgtatcagg aatgctggaa aattacatcg agcgaaatat atttagaaaa
     4081 gtgtatctgt gtgaacaatt atttgaattc caagaaatag acatcgaaca aacagctatt
     4141 tctctaaggg tgactacacc aacgatcctt cacgatctag aaagtctagc cgagtgtcta
     4201 gaatattgta taaaagaaca agtaagagag aagcataagt ataaactcgt attcaaacat
     4261 ggtattgctc tttctgagct cacacagttt ctgtacggtc aatcttattt tttaaagttt
     4321 ttaagttatt attttaatgg tatattcacg agtacagaac tggctgatct tgaatttatt
     4381 tctttgagca aagtatatac aatcaaaaaa atcgtattgg atttttttaa agaaaatgat
     4441 tatttgaaaa ataaagaaat cattatccca gaatttgact cgcggaacat cttgctagct
     4501 ttagtacgtt atgtcaattg ggaaggctat gaaaataaaa atccgtatgt agaagaagct
     4561 tgtaacgagt tgattgatta tgtagagact cattttttta aaagaagata ttcggaagat
     4621 gaaaagtcct ttatcatacg aggaatagag atcgcaatcg gaagaaaggc atttcccctt
     4681 ggactgaaag aagaagataa gaaaagcgca gaaacgaagc cgttatttca attagtctgt
     4741 caaggattgg aagagcaaaa aggaattcta gacttacaag aagaagatgt ctattatatt
     4801 ttttctttgt tcaacagtag aaattatacc aatgagaaca tggagctgtt aagaaaagat
     4861 ttcgaagttg tttataaaaa ttttgttctc aatgacctat cactgaatga attgatttta
     4921 cagattatta gtatcgctga aatcgacgat gcagaaaatt ttattttcaa gcaatccttt
     4981 ttacaatttg tccgtacgtt gtgggcagat ggacaagtat ttttaccgga aaggatctat
     5041 cttctatcag aaaaagaaca acttctgtac ggaaaaattg tagaaatatt ggaagagtgg
     5101 aaaaagaaaa atcaaatcca actaagatgg aatgaaaatt tcattcgaaa attcgtcaaa
     5161 agtctttctt tgatcaacag tgaacaagcg gggagacagg aaatagaaat ttttgttgtt
     5221 tcagaaagtt cagtcaaaca atttttttat cgaacccaat ttcatttgta tgcggaagaa
     5281 ggcatcgctg aaataaatcc tattttattt cgttcattag aagaattgcc tgatgaatgt
     5341 ctatgtgcga aaaaaagagt ggttttgtgc gatgctgcta gctatcaaaa tggattagaa
     5401 actgaaaaga caaagatcta tccaatctca ttaaaaggtg caaacatcca tttgtatcat
     5461 attgctcagg aacttcacct attaaaaaaa catatttctt gatgagacct taattaggag
     5521 accttctaca aagcttttta attgtctgta gaaggttttt atttgagtcc tgattcgtgc
     5581 gaagatctac ttatataaca agctttctct gaaatttttt taaaatgcta ttgacttaga
     5641 gtcaactcta agtagtagaa tagataaagt gtaacaaatc tattttcatt aaaagaagat
     5701 agtacggagg agagaatgta ttatgagtac agtattacat gtattggatg caatcaatag
     5761 ccccgcagat gtcaaaaaat tatctgttga ggaaatgaaa cagttggcag aagagatgcg
     5821 ccaaaaaatc ttgcaaaagg acagcgatgt aggtgggcac gttggtccga atctaggtgt
     5881 agtagaatta acgattgcgt ttcattatgt atttgattca ccaaaggata aaatcgtttg
     5941 ggatgtttcc catcagtctt atggtcataa gcttttaact ggtcgaaaaa atggttttga
     6001 aaaaggacat taccgtgaag tgagcggata ttccaaccaa catgaaagta aacatgacta
     6061 ttttacagtg gggcacacat ctacatctat cagcttagca acaggtttag ctaaagcgag
     6121 agatctgaag aaagaatcag gaaatgtggt agcatttatc ggtgacggct ccctaagtgg
     6181 tggcttagct tttgaaggat tgaacaatgg tggtgtttta caatccaatc taatcgtatt
     6241 agtaaacgat aatgagatgt ctattgatga gaatcatggc agtttatata aaaacttagc
     6301 tgagcttcgt caaaccaacg gtaaaagcag caataaccta tttaaagcaa tgggatttga
     6361 ttatcgttac gtggataatg gaaacgatct ggaaacggtg atccgtttat ttgaagaagt
     6421 aaaagatatt gatcatccga ttgtacttca cgtccatacg gaaaaaggtc gcggttatca
     6481 gccggcaatc gataataaaa tgaaatatca ttggcatgta ccatttgatc tgtccaccgg
     6541 ggaggcaaag caagtaactt ctggagaaac atttaatatg atcatcatgg attatttgga
     6601 taagaaaatg caaacaagta cagctcctat tgccgcagtc aatgcagcga taccaggcgc
     6661 ctttggactg aaaacattcc aagaaaaaca tccagatcat tattttgacg tggggatcgc
     6721 tgaacagcac tctatcactt tcgcttctgc tttggcttct cagggagtac gtccagtcgt
     6781 cttccaatca agtactttct tgcaacgggc atatgatcaa ttatcacatg atttagcgat
     6841 caacgagaat ccagtgatta ttttagtcgg tggcggaacg atctcagcta gtgaccgaac
     6901 acaccaagga acatttgaca ttccttactt atcaagtatc ccgaacatca aatatcttgc
     6961 tccagcaaca aaagaggata tgatctctat gctagattgg gcgttcgaac aaacagcgca
     7021 gcctgtagca atccgaattc ctacacatgg tgtagaacat ggtacagcta tcgcaaatga
     7081 ttatagtatt ccagcctatc aaacagtaaa taatggagga aaagtagcaa ttttagcttt
     7141 aggcggtttt cttgaattag gaaaagaaac agtaaaagct tttagaaaaa aaggaatcga
     7201 agcaacgttg atcaatccag gaacgatcac agaaaatgac gtagaaacat tagataaatt
     7261 aaaagaaaca cacgaattag tcatcacatt agaagatggt agtttgtcag gaggatttgg
     7321 cgaaaatatc agtcgttatt atggtgattc ttcaatgaac gtattaaatt ttggtgcaga
     7381 gaaagaattc acggatagcg ttcctgtagg gcagctttat gaacgttatc atttaacacc
     7441 aaaacaaatc gttgaagata gtctgcgtgt cttgaatatt caataattca ttatgctcac
     7501 catccagata attgtttata ctagtatctg gatggttttt tcattataaa aagcaaaggg
     7561 gtggatgtta tgtatcagca agtagaagaa tatgtcaaaa agttccaaga aaaatatcct
     7621 agttatcaat cagaaaaatt aggtttcttt tcatttgggg atacagaaaa aatggcagac
     7681 gagttgagcg aactagttgt aaaaaagata aagactggta catcaagtgg ttacgatctg
     7741 tataaacaag agaatgagcc tttaccaaaa gttggtcaat tagacgtggt cctgaatgga
     7801 aaaaatgaac cagtttgtat catcaaaaat ataaatgtga ccatcttgcc ttttagtgaa
     7861 gtcacgaaag agcatgcttg gaaagaagga gaaggggatc ggacattagc ttattggcgg
     7921 aaagtccatg ctgagttttt taaacatgct tataaagaag cgttgaacat agaatttaca
     7981 gaagagaagc tggtcgtata cgaagaattt gaagtaattt tcttttagta agaaaggtct
     8041 gctgaaagaa atagctcatt attgtctcct gaatagaaaa gggttacatt tttatatgaa
     8101 gctgtatttt tatataacat tactggagga gatattgtgg atacactgga acaaatcaaa
     8161 ggcggagtcg tcgtttcttg tcaagctttg gaaaacgagc cgctacacag ttcttttatt
     8221 atggggagaa tggctttggc tgcaaaagaa ggcggagcag ttggtattcg agcaaatacg
     8281 acagaagata tcaatgaaat caagcgaatc gttgatttac cggtaatagg gattatcaaa
     8341 agagattacg atgggtcaga agtgtttatt actgcgacag aaaaagaagt ggaagaactt
     8401 ttggagacgc aagcagaaat cattgcactg gatgcaactt ctcgtaaacg tccgacagaa
     8461 aaaacaactg ctgaacttgt ccaaatgatt cacgaacacg gtcggttagc tatggcagat
     8521 atttcgactt ttgaggaagc gcttcaagcg caagaagatg gttttgatct tttgtctacg
     8581 actttagcag gctatacaga atattcacga aagacgcaga cacctgattt tgatttattg
     8641 aatcaaatca tagaacaagt cgatatccca gtaattatgg aaggacatac tgactctcct
     8701 gaacaagtag agaaagcata tgaattaggt gctttttcag tcgtagttgg atctattatc
     8761 acccgtccgc aattgatcac taaaagatat gtcgaagccg caagtaaagc aaataactaa
     8821 aaaacacgca cggcacagat tcttgacaaa aaagaaaaat tgatagatag tttaaagcag
     8881 attctaagaa gatgaaaaaa gcattacttt tcattttgtc ttcaagatct gctttttaac
     8941 gaattttata gaaagaaggc gaaaccatgt ttgaacggag tccttcagaa ttgacagaac
     9001 gtgaaaatta caagttgctg attggttcag tcatccctag accagtagca gtagtaacga
     9061 ctaaatcagc aaaagatata gtgaatatcg cacccttcag ttacttcaat atcgtcagtt
     9121 cgaatcgacc catcttatcc ttggcgatcc agagaaaaca agatgcagta aaagacacag
     9181 caaagaatat tcttgagaca agagaagctg ttatccatat ccttgatgag gacaacgtag
     9241 aagaagtaaa taaaacagca gccaatctgc ctaatgagga aagcgaactg tacctgactg
     9301 acttgacttt aactgattca gtaatcattt cagtaccagc attgacagaa gcaaaagttc
     9361 gttttgaaac atccttatat gaacatgtcg agatacggaa taaaaataaa gtaacagctg
     9421 atttattttt gctagaagta cagaaatatc atttaaatga aacagtctat gatgataaga
     9481 caggaaggat cgatccaaga aaattgaatg ctgtaagccg tttggcagga aatgattatg
     9541 cagcaatagg agaaattttc acgattgcac gtcccgaata aaaaggagca ctagttatgt
     9601 taaaaataag ctataaacca tcgacagatt caaaagaaat gaaaaaagaa tatgaaacag
     9661 tgaatgattt tctgcaaggg cagtacttag aagttccgcc attgcaagac cattttgtcg
     9721 ttactactgt tactttagat ggtaaggaaa tagaaatgcc agatcaaacg attagcggat
     9781 tgtttaatta ctttaacaaa taaatattta ttccgaaaag tgaaaaaaca tataaaaaaa
     9841 cacataaaac taaaaaatta tcaaagaatc ctggtgcaac tgaaagaatt tgcaacggga
     9901 ttctttcaac ttatttgtta tttttttcta aaaaatatta aagattgtta aatttcacta
     9961 tttcatttca aattccattg cctaatcatt aggaaaagtc tatcatgaac tcgtaaatag
    10021 aatatagtaa taaccttgtt aggtgaggct cctatacaaa cataggctgt tgcccagaaa
    10081 cgtcgaaagt cgccaatggg taaaacagaa actgttggat taaggctttt tccaatagct
    10141 aagaatgttt tctttacgtt gtatagtgct aaaactcgga cgatgagatg atgctaggtc
    10201 agaattcttg ttcgaaaagg tttctgacct tttctttata tttttgtgac tgacttattt
    10261 gatgagacaa actcgctcct cacctgacaa gtggattgct gtgtgaggag gagatgcggt
    10321 gaaaaaagat cgattggtgg aggtcgctcg gattcacttc tggttgcaca atacaaccag
    10381 aaaacacaac aagcaaaact gatctctatc atgagagatt catatgtcga tattccaggt
    10441 tacggaatga ataagataaa tgcagcttac tcttatgggg gagttgattt attaaatcaa
    10501 acattaaagg aaaatttcaa atttgaagct ccctattatg caagtatcac atttcaagat
    10561 tttatcgatt gcgttaatga actgtttcct ggtggagtca agatcgatgc agaaaaatct
    10621 ctagatttag atggcgtata tataaacaaa ggagagcaag tgatggatgg taatacttta
    10681 ctccagtatg ctcgatttcg ggaagacaaa gaaggagact tcgggaggat cagaaggcag
    10741 cagcaagtga tcaaagctat ctctcagcag ctgaaagacg taacttcaat attcaagcta
    10801 cccaaagcgg ttgggaaatt acttggtagt atccaaacga accttccaga aagtgtgctt
    10861 ctggattgtg gtatggattt cctcaaagac atatgttaga ataaacaggt ataaatagtg
    10921 aaataaagga atgacaagca agagaaggag gaaaaaatga aaagaagtga caagcacggc
    10981 aaaaatcgaa caggcgctta tattgccggc gcagtgatct taatagcagc tgcgggtggc
    11041 ggttattttt actaccagca ctatcaagaa acccaagcag tagaagctgg agaaaagaca
    11101 gttgagcaat ttgtccaagc tttgaacaag ggagattata acaaagctgc agaaatgaca
    11161 tcaaaaaagg cggcaaataa aagtgcatta tctgaaaaag agatcttaga taaataccag
    11221 aatatatacg gtgctgctga tgtcaaagga cttcagatat cgaatctaaa agtagataaa
    11281 aaagacgatt ctacttacag tttttcatat aaagcaaaga tgaatacctc attaggtgaa
    11341 ttgaaagatc tttcttataa aggaacatta gacagaaatg atggtcaaac cacgatcaac
    11401 tggcaaccca acttggtttt tccagaaatg gaaggaaatg acaaagtaag cctgaccaca
    11461 caagaagcag caagagggaa tattatagat cgaaatggtg aaccattagc aacaacaggc
    11521 aaactaaaac aattaggagt cgttccaagt aaacttggag atggaggcga aaaaacagcc
    11581 aatatcaaag cgattgcttc ctccttcgac ttaacagaag atgctatcaa tcaggcgatt
    11641 tcacaaagct gggtacaacc cgattacttt gtcccattga aaatcattga tggagcaacg
    11701 ccagaacttc cagctggagc taccattcaa gaagtagacg gcagatatta tcctttgggt
    11761 gaagcagctg ctcagctgat tggttacgtg ggagatatca cagcagaaga tattgataag
    11821 aatccagaat taagcagtaa tggaaaaatc ggtcgctcag gtttggagat ggcttttgat
    11881 aaggatcttc gtgggacaac aggtgggaaa ttaagcatta cagatgcaga cggtgtagag
    11941 aaaaaagttc tgatcgaaca tgaagttcaa aatggcaaag atatcaaatt gacaatcgat
    12001 gcgaaggcac aaaaaatagc ttttgacagt ctaggaggaa aagctgcatc aactgttgcg
    12061 acaacgccaa aaaccggtga tcttcttgcg cttgctagct ctccaagcta tgatccaaac
    12121 aaaatgacaa acgggatctc acaagaagat tacaaagctt atgaagaaaa tcctgaacat
    12181 ccattcatca gccgatttgc gacaggttat gctcctggat ctacgtttaa aatgattaca
    12241 gcagcaatcg gtctcgacaa cggcactatc gatccaaatg aagtgttgac gatcaacggg
    12301 cttaaatggc aaaaagacag ttcttgggga tcttttaaaa caacgcgtgt cagtagtgat
    12361 gtatcacaag tagacttaaa aactgctttg atctattccg ataatatata tgcggcacaa
    12421 gaaacgttga aaatgggtga gaaaaaattt cgtacaggct tagataaatt catttttggt
    12481 gaagaccttg atttgccaat tagtatgaat ccagcacaaa tttctaatga agatagcttt
    12541 aactcagata tcttgctagc tgatactgga tatggacagg gcgaacttct aattactcct
    12601 atccagcaag cagcaatgta ttctgttttt accaacaatg gcacacttgt ctatcctaaa
    12661 ttgattgcag ataaagagac aaaagataag aagaatgtca tcagcgaaac agcagtacaa
    12721 acgatcgtgc cagatctgag agaagttgtg caagatgtaa atggtacagc acattctctt
    12781 tctgctttag ggattccgtt ggcagcgaaa actggtacag cggaaatcaa agaaaaacag
    12841 gatgtaaagg ggcaagagaa cagtttcttg tttgctttca atcttgataa ccaaggttat
    12901 atgatggtca gcatgttgga aaataaagaa gatgatgatt cagcaaccaa acgagcatcg
    12961 gaactattgc aatacctcaa ccaaaattat caataaaaaa ttgcttttta agtacagtaa
    13021 aaggactgtg gcgttatcgt cacagtcctt ttttcaaata aacggttttc acgatgtctc
    13081 tttcacaact tctttttgat ttactcacac ttcataaact ttttttgtaa aatatttgag
    13141 aacaagtgga gaaataagtg tacttaataa aatcacgata actaaaggtg aatagtactg
    13201 tggttcgatc aattgacttt gctgtccaat ttgtaaaatg atcaaagcca tttctccacg
    13261 cgaaatcata ccagcaccga ccatcaatga actatgttga gaaaaaccgg caatctgagc
    13321 accaaaataa cctccaagca atttggtcaa aatcgctaca agcgtcaata tagaaataaa
    13381 gagtagttgt tcactaaagt cagaaaaatc aacttctaat cctacactga caaaaaatac
    13441 tggtataaat actgcatatc ctaaagcctc tacattgtgg tatacttctt ctttaacctt
    13501 tgtctgactg acagctatcc cagcaaaaaa agcaccaatg acagagctaa gcccaacaag
    13561 atccgctacg taagacattc ctaaacaaat aactagcgat acgatgataa tagaagaatt
    13621 tgcgtacact ttttctgcaa atgaaagtag gaaaggcgca atccatttga ctaataagaa
    13681 aataaaaaca aaataaatta gctgttcaat caaaacaagc ggtaaagaag cattgctaga
    13741 agcttccccc gttagaaaag ataggctgaa acttagaact aaaacgacta aaatgtcatc
    13801 taccacagaa gcacccaaaa ttgttgatcc ttcttttgta ttcactacgt ttagttcttt
    13861 taatacttct actgaaatac tgacagaagt tgccgcaaga ataatcccaa agaaaatcgc
    13921 ttcatttccc gaaacttgga atgctttgcc tgtcaaccag ccaaaaacaa ccgggaagat
    13981 gatcccaagc aaagcaacga acataccagg tcggaaatat tttttcaaaa gagataaatc
    14041 actttccaga ccagctaaaa acattaataa gatcacacca atctccgaaa agtcatggac
    14101 tagaatatca ggtttgaccc aattcaatcc agcttggcct agcaaaacac caacaagtaa
    14161 ttgtccaatc actgctggga tacctaatct ccgcgagata tgtgagccaa tcgttgttga
    14221 aatcaatatc aggcataaaa taccaataaa ttccattctc atcattcctt tgtataaaat
    14281 atagcccgaa cttagcataa catacattat tgaaaaaata ggaaaatata ctcacaaaaa
    14341 aaccaacaat ccaaaagatt tttttggatt gttggttttt atacggtcta ttttaataac
    14401 taaaaatgat taacgtatag tcatttttct tattctgatg aaattgataa tctcctggat
    14461 gcccatgaaa atcaaaataa agccgaatat ttggaataga agcatcaaac ttttgaatgg
    14521 attgaacaat aagacgaatc cgccaatcaa caacagaata ctactataaa cactccaact
    14581 tttagctttt gtattcatgc tgaagaacaa ctggaacaag ctgttgatga taacagctaa
    14641 tccaagaaga atcggcagga tagaaacgat tgcaggtgca aaagcataga cgatcagagc
    14701 taagatcagg aaaaaaagac cactgaacag accgatactc caagaacctg ttttcctttt
    14761 aaaacggtaa gcctcaaaaa gattcaacaa cccaagcaaa acaagatagg cggtgatcag
    14821 ataaccgata aaatgaaaaa cagcagaagg gtttagcaca atcgcaatcc cagaaataat
    14881 ataaacagca gctcttaata aggcgtattt ttgaatattt tgtttaatcg tctcaaacat
    14941 ataagaaaac ctcctttgac ttattttaac gtgaactagt cattttacca aattaaatgt
    15001 tacaaaatga gcgaaggaga agaatatctc tggaaaaatc aacttctgag gatcttttcc
    15061 atttttttgc cttttgctag ctcatcgatc attttatcta aataacgaat ttctttcatc
    15121 aagttatcct cgatgtcttc tactcgtaca ccacaaacaa cacctgtaat caaggaacgt
    15181 gaaggattgg ggacaggggc ttccgcaaaa aattgttcga aagtcacttg tttttgtagt
    15241 tgatattcta gttctgtttg ggaataaccc gtcagccaac aaatgatttc atctacttcc
    15301 tcttttatac gatcttttct ctccgctttt gctacataca taggataaac gcttgcaaaa
    15361 cttgtcgtaa aaatacgatt ttgcgccata atcagtcacc tttctttttt tcaaattatt
    15421 tactacttat agtatataag aaaaagagaa gaaaaagcga ttattcaaaa aaacaaaaag
    15481 gattgtgaca aaattcttgt caccatcctt ttttccgctc tctgactttt tacaatcttc
    15541 atagctcaag tgcgcatcag ataatcgaat gctcctaaag ctgcagtagc tcctgaaccc
    15601 attgaaacaa tgatttgttt gtatggacta tctgtacaat caccagctgc gaaaacgccg
    15661 gggatattcg ttgcgccatt tttctcggtc actatttcat ttcttggatt catttcgatc
    15721 gttctatcta gccaatccgt attagggagt aagccgacta gaatgaatac tcctgaaaca
    15781 gctagtgtat gcatctccat cgtacggcga tcgatatagg agagagattc tacctgattc
    15841 gtaccgctga tttctttcgt cgctgcatgt ttgataacag tgacattcgc aagagagact
    15901 agtttatcct gtaagatttg atctgctttt aattctggta agaattctag aacatataca
    15961 tgttttgcta acccagccaa atcgattgct gcttcaacac cagaattacc accaccgata
    16021 acagcaatct cttttccttt aaataaaggg ccgtcacagt gtgggcaata agcaattcct
    16081 ttatttttaa actctttttc gcctggtaca ttgatagaac gccagtgcgc acctgtcgcg
    16141 atgatggcgg tttttgcttt aagtgatata ccgttagcta agccaatatt aataaaatgt
    16201 tgctctttat ttaaggaaac ggcctgttga ttcatcataa tgtcgatagg gtaactacgc
    16261 acatgacttt ctacttgctg catcaatttt ggaccttctg tgtaagaggt accaatcata
    16321 ttttcaatcc ctagtgtttc aacgacttgt ccgccgaaag aatcagcgac aagtcctgta
    16381 cggattcctt tacgtgctgc atagatagct gcactactag ctgctggtcc accgccaatc
    16441 actaatacat cataaggttc tttttcaaac aactcttctt caatcaaagg gccagtgatt
    16501 ttttcaacaa tttgttcgat cgtcatgcgt ccgctactaa attcttctcc atttaaaaac
    16561 acagttggca ctgccatgat ttttttatca tcgatttctt tttggaacat cccaccttca
    16621 atcatcgtat gagtaatatt tggatttaat acagctaata tattcaatgc ctgtacaacg
    16681 tcggggcaat tatgacaagt caagctaaca taactgtcaa aatgcaatgt ttgtgttatt
    16741 tttttgattt taagactcaa agattcactg attttcggtg cccgtccact aatttgtaac
    16801 atagccagta aaaaagagga aaattcatga ccgaggggga taccagcaaa aacgattcca
    16861 ctttctttgc caactggatt gatagaaaaa ctaggtgtgc gcatcgaatc tcttttttcc
    16921 caagagattt taggagacat ttctgctatt tccttcgtaa attcagctag tttttgacta
    16981 ttttcactat tatccaaact aacagaaaaa acaataggag attcaatcag tgctaaatat
    17041 tgttcgagat tttgtttagt ttctttgtct aacatatcca ccacctaaat ctttccaaca
    17101 agatcaaaac ttggtttcaa tgtttcgcca ctttctttcc attttgccgg acaaacttca
    17161 cctgggtggg tacgtacata ttgagcagcg cgaatcttat caatcagtgc actagcgtca
    17221 cgaccgattc catctgcatt gatttccata gcttgaacga ttccgtctgg atcaataata
    17281 aatgttcctc gctgagctaa tccttgctct tcatccaaaa catcaaaaat acgagaaatc
    17341 tgatgagacg gatcaccgat catcacgtat tcgattttac cgatagcatc tgatgtatca
    17401 tgccatgctt tgtgagtaaa gtgggtatcg gtagagcaag aaaagacttc aacacctaaa
    17461 gatttcaatg tactgtattg ttcttgtaag tcttctaatt cagtaggaca aacaaaagta
    17521 aaatcagctg gatagaagca aagaatactc cagttcccca taagatcttt ttcactgact
    17581 tctaaaaatt ctccttgatg ataagcatgt gcattaaatt cttcgatttt tttcccaatc
    17641 aatgacatag taaaacctcc aataataatt atttatttat aattattgta atttagttgg
    17701 agttgcaaag tcaatggata ttttgttatt taataaagat tactcaaaaa cgaaggttaa
    17761 ttataaaaat agaagaggtc gcaagaaaat gctactgctg gaaatactcg ggataacgtt
    17821 gagtaacagt ttcctgttct ttcagcatca tgtgtaagtg caatcccgtt tgaaatcgag
    17881 cttcttctgg ttttttatca actaaagcct tgagtaaatc ataatgttgt tccatgatcg
    17941 tttcccatgg aagcccctga atggtcactc gtaaccagcg gaaacgttct aaatgggtat
    18001 tatggtcatc taaccagttc caaacttctt ttcttcctgc aatttcgaaa caagcttcat
    18061 gaaataaatt atctgcacgg aaaaaagcgc gttcgtcatt tattttgact gctttttctt
    18121 gttcttctaa aatcgtttct agcactattc gtgtttgtgt gtccaatttg gaacaacatt
    18181 caatcatgat ttgctcttcc aactgttctc ggacaaagcg agcattttct gcagaaacaa
    18241 gattaatttt ggaaacatac gtaccacttt gaggtatcgt atacacgagt tcttgctgac
    18301 gtagttgaat caatgcttcg cgaatgggag tccggccgat agcaagatgt tcctccagtg
    18361 ccttttcaga tattttcctt ccaggttcta agtcagcata gataatttgt ttacgaatcg
    18421 cttgataagc ttgtgattgc aagctgcttt tcatctttat tcctccaaaa tcatttctat
    18481 gaacgtagta taacagaaga ggtctgaaaa acaatctggt atgtcacatt aactagtaaa
    18541 tttgtataaa tagtaaaatt ttggttgaca tagcgatttt tattgcataa aattcacttg
    18601 aatacaaaaa ctaatatgtt agtttaggag gggaaaaatg attgatttaa acaactggag
    18661 gaactttatc cctgaattat ctcaaaaaga agtagaaata cctcattttg accgtgcatc
    18721 attaagagaa aatggacaaa aaaatcctgt ctggatccat ttcggtggcg gaaatcttta
    18781 tcgaggattt catgcagaaa tcgctcaacg tttagcggat ctaggcgaat tgtccactgg
    18841 tgtcattgtt tgtgaaacat tcgatgaaga aataattgaa agggcttacc aagattttga
    18901 tgatttgatt cttgaagtgg tcatgccaag cagtggagag ttcgtcaaac gtatattagc
    18961 tgcgacagct gacagtctgt attgtcatcc agattgttct gaacactttg ataagatgat
    19021 tcgacacttt gaaaatccta gtttacaatt agttactttt gctattactg aaaaaggtta
    19081 tcgattgaaa gatacaaata ataaatatat aggaccgatt gcagtcgata taaaaaatgg
    19141 tccaaagaag ccatcacata caatgagtat tcttgctgtg ctactttata aacgtttttt
    19201 atctggagct tggccgattg cacttgtctc tacagataat ttttcacaaa acggtagtca
    19261 attacgtact tctttgctaa cgatcgcaaa agaatggcaa aaggaaggtt atgtacaaaa
    19321 tacatttatc caatacttat cgaatgaaga aattgttgcg tttccatgga cgatgattga
    19381 tcgtatcacc ccgaatcctt ccttgtcagt tagcaaaatg ttggcaaaag agggcttttc
    19441 aaatatgtcg attttccaaa ccgcaaaagg aaataatatt gctccatttg tcaatacaga
    19501 ggacatccat tatttaatca tggaagatca ttttcccaat ggacgtccga aattcgaaaa
    19561 agctggggta ttcttgactg atcgtgcaac ggtagataaa gcagatacga tgaaggtgac
    19621 gacttgcctt aatcctttgc atacgtcttt agctattatg ggttgtttac tggggtatag
    19681 gagcatagct gaggagatga aagatccaga tttatcgctg ctagtttctg aaatcgggta
    19741 caatgaaggc ctcccagttg tggagtctcc aggtatcatt gatccaaaga tctttctgga
    19801 agaagtaatt actgtgcgct tttctaatcc aaatattcct aatatgcctc agcgaatcgc
    19861 cacggatacc tctcaaaagg tggcgattcg ttatggtgag acgattaaaa aatatatgga
    19921 aatagaagtt aaagacccgc agacacttgt attcatacca ttgactctcg ctgcttggct
    19981 tcgatacctt attggcattg atgatcaagg aaaaccattc atcccgagtc cagacccact
    20041 attgacagac cttcagcata agctttccga tattcaactg ggtacgcaag atacatcaca
    20101 tattcatgag aaaatggctc ctattttgtc aaataaagaa atttttggtg tagatcttta
    20161 ccaagcagag cttggcagaa aaatagaaga aatgttcatc aagatggtag caggaccaaa
    20221 tgccgtacga aaaacattac aggattactt acaagaacat ggaggaaatt tatcatggaa
    20281 atgactttta gatggtacgg atcacaggaa gaaaagatta ccttagatga aatcagacag
    20341 attcctgcgg tcaaagggat tgtaggcaca ttgatggata taccagtagg agaggtatgg
    20401 cctagggaga ggatcaaaga actaaaagaa gaaattgagt ctcgtgggtt aacactaaaa
    20461 gtaattgaaa gcgtcaatgt gcatgatgcc attaaaattg gattaccttc ccgtgagcag
    20521 tatatcgaaa actataagca gacaatccga aacttggcag aatatggaat agaagtcatc
    20581 tgctataatt ttatgcctgt atttgactgg gtgaaatctg accttgacta ccgcttagaa
    20641 gacggctcat ccacgttagc ttttatatct gatgatattc cagatgatcc aagagaaatc
    20701 gtcgcgcgca tcgaacattc cagcaatgaa tttggattgc cgggatggga acctgagcgc
    20761 ttagctccta tcaaatcctt gcttgaagcc tatgcatcag tagacgaaga aaaacttcga
    20821 gaaaattttg cctattttct ccaatcaatc atcccaacat gtgaagaggt aggggtcaaa
    20881 atggctgtac atccagatga tccgccatac tcgatttttg gattagctcg aatcgtaaag
    20941 aatcgagaag atttagattg gttgtgtcgc atagtagaca gcccttataa cggaatcact
    21001 ctttgtacag ggagtattgc agaagatcca gaaaatgatg tatatgggat tttagcagaa
    21061 ttttgccaaa gagatcgaat cccatttgca catgttcgaa atattaaatt tttagctaat
    21121 cgagatttct atgaggcacc acataaatcc gaatacggtt cattagacat gtaccgcata
    21181 ctaaaaacaa tgtatgacaa cggatttaac ggatacatcc gtcctgatca tggaagaatg
    21241 atctggaatg agacaggaag accaggatac ggcttatatg atcgagcatt aggtgctgtt
    21301 tatctaaatg gattatggga agcaatcgaa aaaggaaaca aaagtaaaga taattagtga
    21361 aaaaaactgt aattttatta tgtaaataag aaggatgttc aaattcttga tacataaatc
    21421 cggaggttgt taataagcat tcggatttat gtatcttatt tggtctagga agtaacttga
    21481 ttttcttttt tcgattgatc catgagtgct tcttctttta attcaaagat atattctgag
    21541 atcctcataa tcactttttt ccagtcttct ggtgtgatga ttccttttaa aatatagatt
    21601 tttttgatat gagaaggcaa ttgtttcaaa gggcagtcgc tgataacgat gttgcagttc
    21661 tccataaaat cattttgtat tttgatcgat tcatttgaaa aaatttgttc tatcttaacg
    21721 atcagatctt tactgatata aaaatcacgc gtatagttca caccaatcac aattcgcggc
    21781 tgttttttgt agcgatcata caaatgtact aggtcttcaa ccatccattg cacattttcc
    21841 ttttctaaaa taactggtaa caagtgttga ttttgttctc tgaaatccat ataaaattgt
    21901 tcaatggcgg tttggacttc tttcaatacg ctatgttctt gataaagcat gaaagtagga
    21961 aggggcgtat ttggttgatt gaagttaaga aatccattat aaagtttatt tcgtgcgaat
    22021 gccaatgagt aaagaatctt ttctttttca ggtataaaca aatcaaatac agtacaaagg
    22081 gactccacca tttctcttga ataaagaaca tgaggaacgt ttgctttttt taaaagtttg
    22141 tattgctcca agcttgtttc ttccgattcg attttcgtga tagaaagtcg agctaaaata
    22201 ttcactaaga tgcgttgttc gcgacaaatt ggcagattag gtcgcaaaat atctacagag
    22261 agatcaataa aaaagtcaat atattcatac tctgtgaatt ctttttgtac gtctttcaca
    22321 gaagttgcag gaaaattctc tttacatatt tttaatagaa aatataattt atctatcata
    22381 ccgctattta gtcggtcaag tacttctttt ttaaaaaaag tattcatcat aaaagccact
    22441 acttgcggat cttcatcata aaattctgta gcagtacttg aaaagatgtt ccaataaata
    22501 tctaatgctg catattgaat ttgtacctct tttccagaaa aagactttct gccattatta
    22561 gaaaaggaga tagacaaacc gtactatgct aaaaatgcat taatcttttt cattttcgta
    22621 tacaaataag aggcactata gtttgtttgc tgactgaaac tgataatcga atttgtctga
    22681 cagctgaaca aagaagtcaa gatctgataa ctgactgatt cgttgcagta tcttccaaat
    22741 agacgataat agcagtaagc cggatcaatt ccttcaaaat tcaactttaa aaaaggtttt
    22801 tgcttatcaa tatgcagttc tgttagattg agacgctcaa agtcttgttc taattctttg
    22861 atgtatagta aaaaatttga ttcagacata tggaaatgat ctgctaaata ttgtgtagta
    22921 ataaagaaac gatgttcaga taggaaaaga aaaatatcta attttgtatt gctttttttc
    22981 ttcaagataa acgttttaat cgcttcttga gtttgcatga aagaggctcc tttttactta
    23041 aattgttaaa acttgaaaat attactgttt ttttcataaa tttagacaaa aaaacagtaa
    23101 acatataggt agaatctcta ctatcttatt tcttgcatac aaaaaaatca aggagtgaga
    23161 gagttatgag atattcaacc atcttaatat caacatttgc agccttaagc ttatcgctta
    23221 ctataaatca gacagtccac acagaggaga tagaaacagc caaatggaca gaaaccaagt
    23281 gggccaacgt caatcgaatt acctttcagg atgaattttc atccttcaat tcaggagtcg
    23341 caaaattaag aaaaggacaa acagcgacca tcaaagcaaa aattgactat tcaggagact
    23401 tagcacctat actacaatca gctgttacat ttgagaatgt tgatcccgct ttgtcgattg
    23461 gctatgacga gaacactttg actatccaac acaagcaagc gatatttacc ttcaccgtta
    23521 cattaaatca ggacttgtta aaaccagcgc tttttactgt caaggtatca gatggactac
    23581 cgaacgatca tcatcattta acgccgtata gtcagcggca gacaattgag caagattcag
    23641 ctatcgactc aggaggagat cttgttgaag aaccaacaga taaaccagaa aatgaaaata
    23701 agccagaagt accgcctaca gaaaatccag acggagaaca gaaaccggaa atagaacctg
    23761 gagaagaacc cgatacagaa actcaaccag agccagacaa tgaatcaaaa cctgaaataa
    23821 cccctggaga aaaaccagat gtagacccag aagaaaaacc agatgtgact ccagaaccag
    23881 atacggattc tggaaaccaa acagtaccgg aaacaaatcc agacacagat aatgaaactg
    23941 aaaatccaga aaaaccagag gtagccccag aagaaaaacc agatgtaact ccagaaccag
    24001 atacggattc tggaaaccaa acagtaccgg aaacaaatcc agacacagat aatgaaactg
    24061 aaaatccaga aaaaccagag gtagatccag aagaaaaacc agatgtgact ccagaaccag
    24121 atacggacgc aagagaccaa ggaataccag aaaaaataaa caaaaaaaca attcaagagg
    24181 atggaaaaaa agagagtaaa aaatcaaatc tagcaattct aaaaataaat gaagagcagc
    24241 tgaataaaaa atcacgaata tttgatagcg cccaatcagc tgaaacctta aaaagtagca
    24301 aggatacaac ctttgctgtc ctgaaacgaa aaataaacag ctaccaaaat ccggagagtc
    24361 acaaaacaaa gttatactgt ggagcggaat cattctatta agtatagcaa caatgctttc
    24421 tgcaaaaaga tttaaacaaa acagatctct ctaacatttg aataatgtct gtgaacgcat
    24481 ttttcaaata aaaagaaata tccagaaaat gaccccaaaa taccagattg aaatctgata
    24541 tttggggtcg ttcatacttt atctttcttc atatttattt taagggatat ctgtttcttt
    24601 tggaagatgg ttcgggatct ttttcacttt caatacatct aaaaagaagg taaagatcgg
    24661 aatgccgaca atcaagcccc aaacgccaaa gaaccgttcg ctaacaagta agaccacaaa
    24721 tgtataaaaa atcggcagtt ctgttttgct ggacatcaac ttcggattca gcacataaga
    24781 ctcaattaga tggacaatca aaatcgtaat caggatataa acaacatctc ggatgcctcc
    24841 ttgggaataa gctatgaaag atagaggaat acaagaaatg ataacacctg ctactgggat
    24901 cagacttaaa atgaaaatca tgatcgctaa actcagcagc tgatgaaagc caaatacagc
    24961 caaggcgatt gtagtgagca acgtatttaa aagagcgaca acaaattgag cttctaatac
    25021 caaaccaaat gtattgacaa acttatcggc aaaatagtaa atatcttgaa agaaccaaga
    25081 aaattcactt tttaaaaaca atcttgagaa tacaattgtt tttttctttt caatcataaa
    25141 aaagaaactt aagatgaatg acatagcaaa cgccactgcc atttttccta tatcctgtaa
    25201 atagccaagc gcaatcgaag cgccattttg aagctgttca aaaaaatcgt ttcgctcaat
    25261 ataagtatgg atatattgta aaacaggatc tgcatctttt ggctgatgct cgtaaaaatt
    25321 aataacggac tggatcatgt caaatgtttg atgaataagc atcgggatat actttgtgaa
    25381 tgccagatag ataaggtaaa cgatcagtgt ataaatcatg atagctaaaa cacctgtagg
    25441 gattcggaca aatcgctgaa tgatttgaac aagatgaatc atcaaataag taaagataaa
    25501 tgtgagcaaa atggttgtaa tcatacttct aactaagaaa agaacaaaaa cgacaaataa
    25561 taaaacagtg agacggcgta ttttttcatt cgccaaaaaa cgctgataaa cggtcaaatc
    25621 gacaacctcc aaataacaaa aaataaacac gttattcatt atatgatgga atatgaaaat
    25681 aagaaagagc aaaaagaaaa accgctaaat gacgttatct tatgagttgg ttttcctcat
    25741 aaaatcgttc atctagcagt ttcagccctt tttctggtct tgatgaaaat tatctagcat
    25801 ttttcgggtc agatgttgca gtgtatccaa ttcttcctgt tcaagtggaa gataagactt
    25861 gatcttttgt ggaatacctt ctgcttgttt ttgcaacgca gcaccttgag cagtcagcgt
    25921 aacatttacg attctttcat cacccgtttc acgctgacga ttaatataat ttttttctgc
    25981 taactttttt agtaagggag tcagcgtacc agaatccaga cacaaatcat ttcctagctc
    26041 tttcactgaa gtctttttct tttcccataa aactaacatc acaagatact gggtataggt
    26101 aagattcagc ggcttgagga ggggagtgta gtgtctaatg atttctttag aggcggcata
    26161 taaaggaaaa catacttgat taactaaata tagatcttcc atttttccac ctccgctgtt
    26221 ttactatagt gtatcatagc ggatttacac aaaaaagtct attcactaac tgctttcaga
    26281 gtaacttcta tatttccagc tgtagctttt gaatacggac acactttatg cgctgcctct
    26341 aataattctt gcgtttcttc cagagaaaga ccttcgatag atccttcaat ctctacacct
    26401 aagacaaagc tcgtttcact ttctgaataa agggaaactt gtgcactgac agtagaagcc
    26461 ccagagatat ttttttgctg tttgatcaat tctaatgcac tgttaaaaca tgcactgaaa
    26521 ccagctgcaa acaattgttc agggttggtt gcattttcga cgcgtttacc aggagctgca
    26581 atattcaatt cgaatgtacg atcgggatta tgcacttctc cagagcgtcc gcctgtgttg
    26641 atcattttcg tagaatacat ttttttcata aaattaccac ctttaattat attttataca
    26701 attgaatttt acacaatata attgtggaaa gcaaagaaat ggattggcat aagataaata
    26761 agagaaagca catgaaacag acgcgctttc tcgaatagca aacatataca aaaaatatca
    26821 gagacaaaaa ataatctcat cataaacatt acatatattt ctcaaaaagt tgttttcttt
    26881 cttcaaaaat tacttcacga tggacctgat gaagcatcca taaataacca aaaggatctc
    26941 tgaacattga gttagtcaca ccaaagtcca tcatttctgt catttcttga atctctacac
    27001 agccatttcg taatgcttta ttatgtgtgt cctcgatatc agagacgatg atattgaacc
    27061 agatcgtatt tggatgttca gcagtaggag cagtcaaacc aagagacgtg ttttcatcca
    27121 gcatatggaa tctcgtacca tacaaggtaa aaatgacttc attattgcct ctagggtaat
    27181 ctgttgcctc aatcagttgt atttcatcaa agattgtttg atacagttct agtgctttca
    27241 aactatcatt taatacaaaa tcgatttccg ttcctttatg cataaagatc tcctctcctt
    27301 ttcagtcgaa cagttactag attcttttat tataccagct aaagaaaacg cattcaaaaa
    27361 aatagcggat ttacttacca actcattcga ttggatgata agtaaatccg cgtcccatta
    27421 cttctgctac gctgctgaca atgacaaagg cacttggatc gatttcttct atcaatggtt
    27481 tcattcggga aaattcatga tcagtcacaa cgatcaataa aacctctttt gactttcgat
    27541 tatacccgcc ttttgcctct agcagggtaa ggccacgtcc aatctcagca cttaagcgaa
    27601 ggcggatgtc ttccaaataa tgttcactca tgaccataac agatttcttt cgattgatac
    27661 ctgtttcgat ataagtcatg acaattgaag tgattgcaat agataaaata gcataaagaa
    27721 actcttctat tccaaaaata aacagattaa gagaaacaac gaatgcgtct gtaaaaaata
    27781 agccaatcga agtattcaag tggaaatatt ttttaaaaat gaggggaggg atcgtcgtac
    27841 cgccgctaga agagttgttt ttatataaaa tcgcaactcc taaagcaaaa atcgcacttc
    27901 caaaaatgac agacaacaac cgatctgaag taatcattgt ttctggaact attgcaatga
    27961 ttaaaggaaa aaccaagctt ccgaaaagta ctttaaaaaa gggtttttta cctaaaaata
    28021 gaagagctag taccaacata acgatattca acactaaaat aactatagct cggtcaaagc
    28081 ctaaagcagc ttccagtaat attcctagac cgctgacacc tccagcagca atatgatgag
    28141 gccctaaaaa catattgata gcgactccta atatgaagag ggcaaaaata atcttaatgt
    28201 atgtccatat aaattgtctc gtttctttca tttattcact tccttaattc attaataata
    28261 ctcttatctt attataactt acttttcacc ttaagttaac tttaattaat aaaaaaatta
    28321 ggctagtcta aattattatg tttcattctt ctagaatata cttctacgcc aaaaactgtt
    28381 aaaaaacttt tactttagaa aattggagaa attgatcgct taagataaat tcaggacact
    28441 aaatagtaca ggaagtagac taaaactttt aaaagtttta agtctatcta tttggcaagt
    28501 ttaaaaaata aaaattcggt atcaaaaaac tgttaccgat aacatttttg aaagcgttgt
    28561 cttttgcttc tctatcactt atagtgatga cgtcatatta aaacacaagg aggaaatcaa
    28621 tggatacagc tgcaatttat catcgaccgg aaagtgaata tgcatttcta tatacgaata
    28681 caagatttcg tattcggctt cgtactagga aaaatgatat caaaaaagta tatgtgctat
    28741 gtggagatcc atataccata acaactgaaa aatggtatca aaaacaacga ccaatgaaaa
    28801 aatgtctaag taccaatgtt catgattatt gggaaattga agtgacgagc gaaacaagtc
    28861 gcttacagta tgcgttccat gttgttgggg aagataacac ggactgtttt tacggtgatc
    28921 aaggaatttt tccttatcga gaaaatgtga ttactgaacc aaatttttat tttcgaatac
    28981 cttattttca tcaaatcgat cgattcacta ttccagaatg ggtaaaagaa acagtatggt
    29041 atcaaatttt tcccgaaaga tttgcaaacg gggacaaagc aaatgacccc gaacacactt
    29101 taccttgggg aagtaaagat ccagaccgag aagacttttt cgggggagat ttgcaaggtg
    29161 tgatggatca tttggattac ttgacggacc ttggcatcaa tggcatctat ttttgtccca
    29221 tatttaaagc cacatccaat cataaatacg atacgattga ttattatgag gtggatcccg
    29281 cttttggcga taaaaaactt ttaaaaaact tgattgatga agcacataaa agagggatac
    29341 gtatcatgtt cgatgctgta ttcaatcata tgggtgtcca ttcaccacag tggcaagacg
    29401 ttctcaaaaa cggagaaaaa tcgatctata aagactggtt ccacatccgt tttttcccag
    29461 tagattctta tcagatgact gacttaccag aaactgctga aaatatccca tatgatactt
    29521 ttgcttttac tccattcatg ccgaaactaa atacagcaaa tccagaagtg caaaaatatt
    29581 tgctggatat cgcaacttat tggataaaag aattcgatat tgatggatgg cgtcttgatg
    29641 ttgctaatga agtcgatcat catttttgga aaaaattcag agaagcagtt acagaaatca
    29701 aaccagacat ctatatcctt ggagagattt ggcattcctc tcaagcttgg ctgcaagggg
    29761 atgaattcca tgcagtgatg aattatgcat ttacagattc gattaaagat tattttgcaa
    29821 aaaagaaaat cacagcttca caaatggtca gtggaatgaa tcatcagcaa atgctttaca
    29881 gagatcaggt gaacgaagga acattcaact tattagattc tcatgatact gccaggatct
    29941 tgaccctttg ccaaggtaac aaagaattga tgaagtctgt gatggccttt atgtttcttc
    30001 aaaaagggtc tccttgtatc tattacggga cagaaatagg gatgactggt gaagatgacc
    30061 cggattgccg caaatgtatg atatgggaga aggaggaaca agatctagag ctattcggtt
    30121 ttataaaaga acttgtttct ctaaggaaac agttgtctaa gattatttct gaaggttcta
    30181 ctcagtggct aatagtaaat gatcgtgaag ataagctcta tttcacacgg aaactagagg
    30241 gacagatcat ctatgtttac tttaatcagt caaaagaacc ttgggtagta gaacaggaaa
    30301 atgaggtgat tcttagtcaa aattgtcagt tgttagaaga cgggaaagca gagatacgac
    30361 aatacggatt tttgatcatg tgttgaaaac tgttaccggt aacaacaaga aagcgtttgc
    30421 aaatgaagat ttgtgcccat tataataagg gtgtaacagc acgttgaata caaaggagga
    30481 aatgaagatg aaaaaaagaa gtgtgaaaca gttgggttta gggttaatct ctttaggaat
    30541 cttaggcgga ttagcggctt gtggcaatgg taactcttca gcagaagggg aagccgatga
    30601 aggaaaaacg ttaacagttt ccgttgattc tggatataaa gattatataa acgaaataaa
    30661 aaacactttc gaaaaagaaa acgatgtgaa aatcaagcta gtagaaaagg acatgttcga
    30721 tcagttggaa tcattagcgt tagatgggcc tgctggaaag ggacctgacg ttatgatggc
    30781 agcatatgac cggatcggtg cgttaggaca gcaaggacat ctggcggaag taaaactggg
    30841 aaatgaagca gcttacgatg aaacagacaa agcccaagtg acttatgatg gaaaaatcta
    30901 cggagaacct gcagtaatcg agacccttgt tttgtactat aacaaagatt tagtcgatac
    30961 agcaccatca acgtttaaag atttggagaa tctatccaaa gacagtcgtt ttgcttttga
    31021 gtcagaagca ggaaaaaata caggattttt agctaaatgg actgactttt attattccta
    31081 tggtttaatt gcaggttacg gtggctatgt atttggtgat gatggcacaa atccttcaga
    31141 tatcggtttg aataatgcag gtgctgtaga aggaatctct tatgcaacag attggttcaa
    31201 aaatgtttgg ccaaagggaa tgcaagacat aaaaagtgca ggagacttcg ccagccagca
    31261 attcatgtcc aataaaactg cagcaatcat tgacggtcca tggcaagcgc aaacatacaa
    31321 agaaaacaat atcaattatg gtgtagccaa aattcctact ctaaataatg gacagcctta
    31381 tcaaccgttt ggcggaggaa aaggatgggt agtcagcaat tatgctaaaa acaaagacct
    31441 ctctcaaaaa tggcttgatt atgtaacgaa tcaggaaaat caagaaaaat tctttgaaat
    31501 ggtaaatgaa atccctgcaa accaacaagc tagggaaaca gcaaaggcta aaaacgatga
    31561 attaacaaca gctgtgattg aacaatatga aacagctcaa gcgatgccaa acatcccaga
    31621 aatgggcgaa gtttggacag gtgcagaaaa cttgatgttc gatgcagcat caggttcaaa
    31681 aacaccaaaa gaatccgcag atgaagcagt aaaaacaatc agtgaagcca tagaacaaaa
    31741 atactgatta aaatgataac cgtccatttt tataaaaaat ggaacaggtg cttcagataa
    31801 aagtggcaag agcgagatgg aaaattatct tgctcttgtt gccattatct taaaagcagt
    31861 ttgcggttta gcaagtttag agggggcatt cagatgcagc aagataaaac aagcaatatc
    31921 aacgaaaaaa aaatcacgct ttgttcactt attccaggga tggggcagtt tgtaaatggc
    31981 caagctttta aaggtatcgt ttttttcgcc atattcgtcc tattcattgg tcagatgctt
    32041 ctgggcggat ttcatgcatt ggtaggattg gttactttgg gaagtatacc aatggaagat
    32101 cattcattat ttattttgat tgaaggcact ttgcaattca tcattacaat cattttcttg
    32161 attttttacg gtttgaatct tttagacgct tatcgagtag cgaagatgcg tcaagagggc
    32221 aaaaaaatca atcggacgat gaaggaagtc atacataata taggtgatga aggttttcct
    32281 tatctattga cacttcccgc ttatcttctc atgattttta cgatcatttt cccagtccta
    32341 gttacattgt tcactgcatt tactaattat gacttcaatc atattccacc agccagttta
    32401 attgattggg taggggctaa aaactttttt agtatcttct ttttaagctc atatcgtaat
    32461 actttttttg cagtcttttc gtggaccgtg atttggactt tatgtgcaac aactttgcaa
    32521 atcacccttg gtattctcac agcggttgtt gctcaccaga aatttattaa attcaaacgt
    32581 attttcggta tcattttctt attaccatgg gcggtcccag cttttattac tatcatgagt
    32641 ttttcgaata tattcaacga tagcgtaggt gccatcaata ctcaagtgat tcctttcata
    32701 aaccagcttc cttttgtaga tatcagtgca atctcttgga aaacggaccc gaactggacg
    32761 aaagtagcaa ttatcttagt gcagggctgg ttaggatttc cctatatcta tgtgatggtt
    32821 acaggaatct tacaatcgat ttcagaagac ttatatgaag cagcaaaaat cgacggagca
    32881 aatgcatggc agcgcttttc aaacatcacg cttcctgctg tcttcctagt ggcagcgcca
    32941 acatttatta cacagtatac ggggaatttc aataatttct ccatgatcta tctgtttaac
    33001 aatggcggtc ccggaagcgt aggcggagga gctggttcta ctgatattct tatttcctgg
    33061 atctataaac ttacgactgg aacttctccg cagtattcta tggcttcagc aatcacgttg
    33121 attatctccg tcatcgttat ctgtgtgtca ttgctggtat ttaaaaagac aaatgcgttc
    33181 aatatggggg attaacaatg aaaaaatttc attcgagtgc tcgattccaa aaacgacttt
    33241 ctcacttttt tacttacttt tttcttttaa tactgtcagt cattatcatc tatccgcttt
    33301 tgatcacagc aagtactgcc ttcaagtcag gaaatattgc agcttttagt ttagatcttt
    33361 caagtgactg gactttagga aactttactc ggctattcag tgaaacactt tacgggactt
    33421 ggtataaaaa tacattgatc atttctgtcc taacaatgat cgtacaagtg actgtagtaa
    33481 ctttggcggg ctatacttat agtcgctatc gttttatcgg ccgcaaatca agtttgatgt
    33541 tctttttagt gattcagatg gtaccgacta tggcagcatt gactgccttt tatgtcatgg
    33601 ctttcttatt agaagcgctc gataagtact ggttcttgac aatgatctat ataggcggtg
    33661 gaattccaat gaatacttgg ctgatgaaag gatactttga cactgtacca atagatttag
    33721 atgaatctgc taaacttgat ggggcagggc atttcaggat ttttttccag attgtattac
    33781 cgcttgtcaa accgatgctc gccgttcaag cattatgggc ttttatggga ccttttgggg
    33841 atttcatgtt agctaagttc ctgcttcgaa cacctgaaaa tcagactgtt gctgtcggct
    33901 tacaaacatt tatttctgat gtgacaaacc aaagagtctc tctttttgct gctggggcaa
    33961 ttttgattgc actaccgatt tgtctattat tcttcttttt acaaaagaac tttgttaccg
    34021 gcctgacatc tggcggaaca aaaggatagg agcagagtat catgcaaaca tttccgttaa
    34081 actatttttc cgcattacgt acgccaactc aagtgtttgc gggacgcaaa ctattatcat
    34141 ggcctaaatt tttcttgata tttgtatttt tagtttcctt gatggtcatg cctgtgactc
    34201 ttttttatgc caatcagatc caagcgattc cattagaaca atttctatcc gttcattcgc
    34261 tgatcgatga acaaggaacc caaaaatttt ctgaacttga attatctgaa actgggttac
    34321 aagcatcgca acaaacgata gctgtgaccc ctgaaatttt ggtaggtgtg tctttatctg
    34381 agaaacaaca atccgatcat ggaactttta ttgattttga gaaggaacaa tgggtgatcc
    34441 aacaaaagga taaatctggt atacgccgct atacgatgaa ttatagccca tctttccaac
    34501 cagattctgt acgtacgccc gaagatttcc aacgattttt agaaagagaa ttttatgcca
    34561 gtaatcgtcc aacaatcatt ttatcttata gtttaagtct tggtcttgtc ctatttgtca
    34621 tgacgagtct cattttattc ggggcttcct ttttcttgtg gatgacaaga aaaagccaac
    34681 tttcatccat tcatacattc aaagagagtg caaatttgat gctgaatgtt atgggaatag
    34741 gttccatggc agcagcagtt gtagggttta tccactttga ctttatcttg atgctaagtg
    34801 tccaaacaac gataactgtc ttgctgcttt tatgggtttt tgtcaaaaca agattcaaag
    34861 ataagcgtgt cgaatgacaa gtttaagcga tttatgcgac aatgaatgtg aaaaaaatga
    34921 aaaataaagt agtttttgaa aaatttctga aaaaattaaa cttcttagtt gattcttttc
    34981 ttttttagta ttaacgtaat agggtagttt ttttaaggag gaaaatcatg ttagagaaaa
    35041 ctttatacaa tcaattattt tcacgttctt tctcgctccc tgtcgaagta aattattggg
    35101 acggtacaac gaaacaatac ggagatacgg acactcctcc ccaaatcaaa atcaatatcc
    35161 atgaagaaat cccaatgaaa gagattacaa gtaacgcttc tttggcacta ggagaagcct
    35221 atatggatca tcgaatcgag atcgagggaa gtatccaagc attgatcaac gatgcttatc
    35281 agcaagcaaa cagcttttta cgaggaaaag attatctaaa atggctgcca aagaaagaaa
    35341 aacatacgaa acaaaaaaac aaagaagata tccatgcgca ttatgactta ggtaacgact
    35401 tttataaact ttggctagat ccaactttga cttattcttg tgcttatttc aatacacctg
    35461 aagatacgtt ggaacaagca caaatcaata aagtccatca tatcttagac aaactcttta
    35521 tcaaagaagg cgaaacgttg cttgatatcg gttgtggctg gggaacattg atgttcactg
    35581 ctaccaaaga gtataatgtc aaggcaactg ggatcacact aagtgaagaa caatacgatt
    35641 tgattaccaa aagaataaaa gaagaacatt tagaagataa atgccgtgta ttattaatgg
    35701 attaccgcga actaaaaggc gaaacgtttg atcatatcac aagtgtaggt atgttcgaac
    35761 atgtaggttc tgaaaatctt gaaggttatt tcaaagtggt aaaagattta ttgaaaccaa
    35821 aaggaacagc tttgatccat ggaatcagcc gacaacaagg cggtgcgaca aatgcttgga
    35881 tcaataaata tattttccct ggcggttatg tccctggtgt tactgaatta gttgataata
    35941 ttacaaaaaa cgatttgcaa ctgattgatt tggaaagctt acgtcgtgac taccaattga
    36001 cattagaaca ttggacaaag aattttcatc aagtccaaga tcaagtcacg aaagaaatgg
    36061 gtgattcctt ctatcgaatg tgggatctat atttacaagc ttgtgcagct tcatttgaat
    36121 caagtaatat cgatgtgatt caatatttgc ttgttcaacc tggaaacaat gacatcccaa
    36181 tgcatcgtgc ataattgagg caaaagtact gtttaaagac tatttaaaaa gaagctaagt
    36241 tttatgatgc tccagaagtg aacttttttg tctaacttct aggattgtct ctaaagctta
    36301 gtttcttttt ctttatattt tcataataaa agtttggttc tttaattttt aaacatgaca
    36361 gaaaattttt tcttcgttat acttgtaata gaatactatt ttataacaaa ggggatcgaa
    36421 tcaatgaaaa aaactgttat ttatactagt ttatttgcag ctttgttttt agctgcttgt
    36481 caatcaaata ccaatcaagg cacatctggg aatacgtctt ccagtagcga acagcgctct
    36541 tcacaggtat cggactcctc aacaaaagca agcacatctt cgtctagcca gacaaaaagt
    36601 tctagtgaag caagtactca gtcagatatc aaagtgtctg cagctcgtgc gatcgaattg
    36661 ttccaagata aatacccaga tactgcaatt actagtttgg aattagatag tgattgggga
    36721 tcttacttct acaagataga aggtgtcgat gatcaaaaag aatacgaagc aagaattgat
    36781 gctcaaaatg aaaaaatgga gacagagaat ccagaaactc tagatcgaga tgaacaaaat
    36841 ggtcaaaaga aaaaagaaga tggtctggat gttgataaat tgatcacgat tgaggaagca
    36901 gcaaaaatcg ccgtcgacaa agtaggaagc ggtacggcaa cagattggga tttggataaa
    36961 gatttaggta ctacttattg ggaagtcaaa gtaaaagacg gcaatcaaag tacatcagtc
    37021 aagatcaata gccaaacagg cgaagtactg tcaactgaac aagatgatta agaatttctt
    37081 cggaaaacaa gagttgattt ttcttttagt catgatacac tagacaaaat aacttgtttg
    37141 aaggagcgat ttacttgagt ttagaaacga cctttgccaa tcatatcttt gccaatcctt
    37201 tgatgaatgc atctggtgtc cactgcatga ctacccagga attagatgaa ctggctcatt
    37261 cagaagcagg agcatttatc actaagagct gtacgatcaa tgaacgaaaa ggaaatcccg
    37321 aaccacgcta ttttgatgtt cctttaggga gtatcaattc tatgggactt ccaaacttag
    37381 gtttttctta ttatctagag tatgctcttg cgtatgaaaa agtgcaggaa aaccaaaatc
    37441 aaccgttatt tttttccatt gccgggatga gtgtccagga aaacttggaa atgcttgaga
    37501 aaatagaaaa aagtgggttt aatgggatca ctgaattaaa tttatcttgt cccaatgtgc
    37561 ctggaaaacc acaactagct tacgattttg aggccactta tgaaacactg aaagaagtat
    37621 tcagcatctt ttctaagccg ctaggaatca aattgcctcc ttattttgat tttgctcatt
    37681 ttgatcagat ggctgatatc ttgaatcagt ttccattgac ctatgtcaat gctatcaaca
    37741 gtgtgggcaa tggtttgtat atcgatacag aacaagaagc agtagtcatc aaaccaaaag
    37801 aagggttcgg cggcattggc ggagagtata tcaagccgac tgctttggcg aatgttcgcg
    37861 ctttttatac acgtttgaaa ccagaaatcc aaatcattgg tacaggtggg attcggacag
    37921 gacaagatgc atttgaacat ctgctatgtg gcgcaagcat gttacagatt ggtacagagc
    37981 ttcataaaga agggccggaa attttttcta gaatcataaa agaattaacg cagattatgt
    38041 cagaaaaagg atatacgtca attgacgaat ttaaaggcaa attacgcacc atttcatagc
    38101 aaagagacga aggtcatgat tgatcttcgt ctttttttat aaaaaacact cgtctgttca
    38161 ttcctgtgca agcgtactca ttgtatgtta gacgaacttg tgggaaaata acagaggcaa
    38221 aaaggaggat aatatgaatg atgcaacaga attagcaaaa gagcttaaag aaaaagaatt
    38281 tagttttcaa gaactagtta cggatataca gaaaaaaata aagaagcaaa atcatgaatt
    38341 gaatgcgttt gtcgcgcttg aaccattcga gagtaattcc cacgagctat tgattcccca
    38401 gtcagaaaaa gggccattgg ctggtatccc atttccttta aaaatgctcg gtcaagaaaa
    38461 aaagggatgg ctagctactt caggatctcg tttatttgaa acacaccgag cttctcatac
    38521 atctaattat gtgcggcaag cagaagcgat aggtctagtt ccttttggac aaaccaatgc
    38581 gccagagttt ggtttcaaaa atattacaga cccagtcatc tatggcccag caagaaaccc
    38641 ttggaacctt gaatgtacac cgggcggatc aagtggagga gctgctgctg cagtttcatc
    38701 aggaatcgtt cctttagctg gtgctagtga tggcggtggt tctattagaa tacccgcttc
    38761 gttttgcgga ttgattgggc tgaaaccttc gcgagggacg atgccagttg gtccatatgc
    38821 ttggagagga tggcaaggag ctgctattga tttcggcttg acagtttcta tgagagacac
    38881 ggaggcttta ttttatggga tgagaagtat ccattccggt gcgccatatc aagtatcgcc
    38941 agttgagtgg caaacacatc caagaaaaaa acggttgaag atagcttttt gtgttgattc
    39001 accgatccac tcacagatta gtgaagaggc agtacttgct gtaaaaaaag ctgtagattt
    39061 ccttggaaaa gaagggcatg atttgacaga gattccttac ccactagatg gtcgtaaact
    39121 gatcacgtct tattatcaga tgaatggcgc agaaacagca gcaatgatcc gctcgattga
    39181 aacaggcatc cagcgagctg tcagaaaaga agaacttgaa cccatttctt ggactttgtt
    39241 ccaatatggt cagaagctct ctgccgctac ttacatcgat tctctgcatg tatgggatga
    39301 agcagcaatt gtcatggaaa acctacatca agaatacgat ctattccttt caccaacgac
    39361 tgcatttacc gcccctaaaa tcagcgaaga tttgcaaagt gatgcgataa gagcacagat
    39421 ggaacacatc agtgattgtt ctgaagtaga aggtttagac gttgtttctt ccatgtttga
    39481 ggagagcttg aagatcacac cttatacaca gttggctaat ctgactggac aaccagcaat
    39541 cagcttgcct actcatttga caaaagaaaa catgcctcta ggaatccaat ttatggctgc
    39601 cagaggaaga gaagatttgc tatttcaaat cggctatcta tttgaagcaa atcatcagtt
    39661 ccatttacca aatccatgga aatagcagaa acaaggagaa gaagaatgaa gaaaaaaaga
    39721 ttgtttgctc taataactag tgcctttttt attttaagcg cttgcggtac agctgccgct
    39781 aatcaggaag ataacagctg gagtaatgta gaaaaaaaga aagaattagt agtagcgact
    39841 tctggcacac tgtttcccgc atcttattat aatgatcaaa atgaattagt tggttatgat
    39901 gtagatttgg caaaagaggt ggctaaacgg ttaaatgtca aaatctcctt taaagaatac
    39961 aacgtggatg gacaaatcac ttctgtttca aaaagagaat cagattttgc tgcgaacgat
    40021 tttggtatca caaaagaaag agaaaaaaaa ttctcccttt cagagacttt caaatattca
    40081 tttgacagta tgatcgtacg aaaaaaagat gattcaggaa tccactcact tgaagatctt
    40141 aaagggaaaa aagcagctgg cgaacccaat actagctata tgcgtttagc ggaaaaacac
    40201 ggagctaaat tagtcacata tgacaatgcc acgaatgatc agtatttaag cgatgtagca
    40261 aatggtcgaa cagatgttat tctaaatgat tattatctgc agaaaatggc cgtatctgct
    40321 ttaccagata tccctgtaaa aatactggag aacgtttatt tcaatgaaaa cgaaagtggt
    40381 tttttattga aagaaggaaa tgatgctctg aaaaagaaaa tcgatggcgt attaaaagag
    40441 atgaaagaag atgggacgac aaagaaaata tctgaaaaat attttcaaac tgatgtttca
    40501 gtcaaaccga aagaaacgat ggctgagtcg gtgagtgagt gatgtacttt cctctaattg
    40561 atttttccct catgtggact tcacttcctt tcgtactgca aggcttggta tacacattag
    40621 ggattggctt cgtgtcgttt cttttaggaa atttggtagg gttgcttttg acagttttag
    40681 gtcttttgga ttggctgcct ctgaatgtat ttattcgttt ttatttatcg ttctttagag
    40741 gcattcccgc actagtcctg ctgtttctgt tatatttcgg gttaccttat caattaagtg
    40801 ccttaacggc ttcagtcatc tgctttacga ttaccagcag tgcatttatt ggtgaaatct
    40861 atcgaggatc actagcaggc gtttcttcag gtcagtggga cgctggttta gcttctggtt
    40921 tttctttctt tggggtattg aaatatatcg ttttgccgca agcttttcga atctcagtac
    40981 cggcactcag taacgtagct atggatctag tgaaaggtac ttcgttagca gcaacaatca
    41041 cagtgccaga aatatttcaa aaagcaaaga tcataggcgg tcggacattc gattattttt
    41101 ctctctatat tttagttgca ctgatttatt gggtcatttg tatcgggatc gaaaaagtgc
    41161 aacagtattt agaaaaacgt tctatccatc agtcaatctg aaaaatagaa atggtgctag
    41221 cgtggctggc accatttcta ttttttgttt cttgtatatt ctgcctagta ttttaaaacc
    41281 atttcatgta aaatgtaaat cgaaaatatg ttcggaggta gaaaacatga agaccccgct
    41341 aaccatcgaa atagaatcct cgttatacca atattgcatc gagcaaggcg gcttggttgt
    41401 agaagaagtc acgatgcctg atgaccaagg aattgtagat acgcttagct gcttgacaaa
    41461 atttgatgga agccgagaat ggcgatgcta tgagctgaaa gtgacaaaag cagattttcg
    41521 ctctacagcc aaactgtcat ttgttggaca ttataattat tttgttttac caagtaaact
    41581 atatgaagaa gtaaaaactg aaatccctac aggaataggt gttttagtgt atcgtccgta
    41641 cacggttgaa gaggagatgc ctgcctctgg tacatttctg attgcgaaaa aagcagcaaa
    41701 gaaagagctt gctgtaccgg aagaagcttt gacaaaccgc ttcatggctt ctttattcag
    41761 ggaagtaaga aaagcaaagc aaatggagcg aggcgtaaaa tattttccaa aagatcaatt
    41821 gtacaaagaa ttgaaaagac gttcagaaaa tcaagatcca ttttctaacg aacgatatta
    41881 tgaacggttt ttagaggaaa tagctagtca ggcaatcaat gagttgcaag aagaagttat
    41941 cgcgcttcag catgattatg aatatttgag gcaacaacag cagatccgtc ggttgcctac
    42001 agagccattg gagtgaaaaa tatgtactat ccttatttaa gaggaaaaca atttgaccta
    42061 ttagcattaa aagaagcact gtcgcgagga ttgctctcca ataaaatcca accagtgatc
    42121 gaaccagtac gtgattccgc tacgcttaaa aatgtgatcg aattatttca aaaaaagcac
    42181 catccaatcg ctgtgatcca aaatccccaa gtaggacaat tcaaattatt cgatcagcat
    42241 gtgcacagtt ggacagtcaa agaaaatagc tctgtcgtcc ctgcacagat cttaacgcca
    42301 gaaaatctca gtgaagtact ggattcacct ccagcgtttc ttgttttcga tggacagcac
    42361 tacccaaaag atacagaggt gtggaaacag ttggcaggag ttgattcgaa atttttgata
    42421 ccagatacta gtcgctttcg catctggctg cccgaaaaca aaattgtgat ccgtgactct
    42481 tttcaaacga gaaagcatgt tgaaagttat gcagataaaa cagatgactt ttttagtgat
    42541 gactatcttt ttttccacgc agacggatat attggatttt ctgatttcac gatcgaaggt
    42601 agccgttatt tcgataaagg gttccctagc cgagcgcttg ctatccatct aacgtatatt
    42661 gatgcttacg gcaatatacg cgtgaaacat tttgtctctg acagtaacga ctctgctaaa
    42721 gaccaagcat tgaagtttct tgaagcagga gataaaatga aaaaatggat catgcgtcac
    42781 catcatcaac tcttgattac ttcaggaatg attgaattat tggctcttta ccagcaacaa
    42841 aaattccctg gactgggagt gttgaaaaag tggtcactta tgcatcattt ggaacttatt
    42901 agtcacctgc tagatcatcc aaaagattgg cttaaatatt attcaaaagt tcaggaacta
    42961 tatgaagtga tccaatgatt agataatgta aatgaaaaag gaatagaaaa gaggaaactg
    43021 gatgtatatt cggcaaacaa ggaaagaaga agtagaagaa gtggtagaaa tcattaatgc
    43081 cgcagcggat ttcattgctt cgcaaggctc tcctcaatgg caaaacgggc agaaaccaac
    43141 aaaagaaacg attttgaacg atattgaaag aaaagaaagc tatgtattaa tagtggaaga
    43201 tcaaattgct ggaacagctg cattagtctc aggcgtggat cccgtttaca caaaaataga
    43261 tggtagttgg aaagaatcaa ctggtcctta tttatcgatt catcgtgtcg ctttagcaga
    43321 aagtactcga ggaaaaaaac tagcaaaacc gttcttagaa catttgttga cgattgcagc
    43381 cagcaaaaat atccaagata tccgtatcga tacttatcca gctaatgaac cgatggaaaa
    43441 gaccatctat tctgctggat tcacttatca agggatgatt gaatttcctt ttgaacacgg
    43501 cgaaagaaaa gcatatcaaa taatcatcaa ttgactataa aatcatctga gcaaagataa
    43561 agacattaac actactgaaa aaaacaatca tatgatagcc aagaggttgt aacagaagtg
    43621 gccagcttca aaaaacaaga aagaatttcc gaaaatgctt ctcaaatttt tgtggaattt
    43681 tagcgtattt tacgaaatag ctgctttctg aaactccctt catcgagagg tcgtgacata
    43741 gcttttgtca cgatctctcg gcttatccta cgagtattat tcgatacatt tatatcaata
    43801 atcctttttt tattttatct gcagcttctt ggaacgctcc atcgtttgac acgactaaaa
    43861 gtgaggggat agctttcaaa cgtttcaact gtgctaaatc ttctacataa accgccagtc
    43921 tggctgaaat ctgttcagat gaatctccac gttttttcag gcgcgattgc aatgtttctt
    43981 tagagatcgt aataaagata ggacggacta ccgtcccgaa atactcatat aaatgccaaa
    44041 aaccatttgc tgtcaaaacg gcgtaacaat ttcctactgt cagtttcttt ttaatttctg
    44101 ctttactgga accatattta tgttgagcat attggtccca ctctgcaaac tcatttccct
    44161 tgatcatctg attgaatgta ttgtcagaaa caaaataata atcctcttga tctttttccc
    44221 caggtcttgg tgatcgattc gtgtaagtaa tgatcttttg ttccggctga aaaatagctt
    44281 ctgcgagtga agtttttcca gaaccagaag gaccgataaa tacatagcaa taattcattg
    44341 tcatttctcc tttgatgatt gaacaagtga aaaagctttg gaaaatattt ccaaagcttt
    44401 taaaagtaac tttgcttttt tgtattttat accagcaagc cagtcacaat agcacttaaa
    44461 aagctgacta aagtcgctgt tagcaaaatt ttcaatccgt gttttgcgac aagatttcct
    44521 ttttcttcat ttaatccctt catcgcacca gaaatgatcc cgatagaaga gaagttggca
    44581 aatgaaacga ggaagacaga tataattgct gttgtacgct cagtaaaatg gaaattacca
    44641 tttgctaatt ctgtcatagc aacaaattca tttgtaacca gtttagtcgc catgatacta
    44701 ccggcatcca ctgcttcttt ccatgggatt ccgctgatga aggcaagagg ggcaaagatg
    44761 taacctagga tctcttggaa agtgatgccg aatatcccgt ggaagatagc attgatcatg
    44821 gcaatcaaag caacaaaacc gataagcata gcagcaaccg tgatcgccac atggaaacca
    44881 tcaagaatgt attctcccaa catttggaaa aatgtctgtt ctttgttttc ttcaatgatc
    44941 agctcatctt ctttttcttc taatacatag ggatttacaa ttgaagccag aatataaccg
    45001 ccaaataagt tcaaaacaag ggcagtgatc acatatttag aatcgatcag tgccatataa
    45061 gatccgacga tcgacataga aactgtagac atagccgata cactcatggt gaacaaacgt
    45121 ttctcagata ggaagggtaa ttcctttttt atggaaataa aaacttccga ttgccctaaa
    45181 atagcagaag ctactccatt ataagattcc aatttgccca tcccgttgat tttacttaat
    45241 cctagaccaa cagctttcat aaataatgga agaatcttga tatagcgtag aataccgata
    45301 atagcagaaa taaatacaat tggcatcaat acggaaagaa agaaaggtgc acttccttta
    45361 tttgctacac cggcaaaaac aaagtcaaca ccttgcccag caaaagcaag aagatgatca
    45421 aacatttttg ccaatacaga aacaaccgct gtaccaaaag ttgtacgtaa taatacgaaa
    45481 ccaagaacaa gctgtaaaac gaacatcaca attagtggtt tcaatttgat tgcttttttg
    45541 ttactgctga tcaaaaaagc aagccctaat gtgacaaata aaccaataat acctaataaa
    45601 taactcaaat aatcactcct attccaaatt ccgttttatt ttacctgttt tgcaaataaa
    45661 atactaatct ttagtgaaat tttcattact tttttagagt gaaacgcatt cattttccat
    45721 tagaaaataa agcgaacaaa ataaaaggtt taaaaagtgt aacgtcttag taaagtctat
    45781 aaaaaaacga aactatcgat taagctaata gtttcgtttt caacatttat aagtaaactt
    45841 tttctattgg taatatagat tttcggaagg gtagacaggt gcgcaggtaa tatcgattcc
    45901 tagttttttc aatgtttgtt catcattttt attgaccatc acagtagagt gggcttgtgc
    45961 tccctcaagt tcagctagtt tatcataagc aacttgagcg attggattcg ttactgcact
    46021 gattgataaa gcgatcaaga cttcattgat gcttagtgca tccaaagagg aatgaagtgt
    46081 ctttgatttc aatccttgta ttgtttcaag aactaatggt gacaataaag gaatgtcatc
    46141 tgcgatatgg gctaaatgtt ttactgcatt taagataact gccgctgacg catccatcaa
    46201 tgaacttgta cgcccggtaa tgatgacttc atctggtaat tcgattgcaa tcacagcaga
    46261 aggatctttt gtaggacttt gcgcttgaat cttatctgca tagtcatggg cagggactac
    46321 cacgtttcgg tcttcaggac gtaaaccgac ttcttccata atcagtttga ttcgattaac
    46381 tgcttcttcg tcgatcaatc cttttttgaa gtcgcattct gtttggaaat aacgacggat
    46441 gatttcttgt ttagaggctt cttggacaac ggtatcatcc acgatcccaa atcctacacg
    46501 attcacaccc atgtcagtag gagattgata aacagattct ttaccagtaa ttttttcaat
    46561 aatacgtttg attacaggaa atgtctcaac atcccgatta tagttcacag ctactttatt
    46621 gtaggcatca aagtggaagg aatcgatcat attgacatct tttagatcga ctgtggctgc
    46681 ttcataagca atgttcagcg gatgtttcaa cggaacattc catactggga aagtttcgaa
    46741 cttggagtaa ccagctgcat gtcctttttg gctttcatga tacagttggt tcaagcaagt
    46801 agcgagcttt ccacttcctg ggccaggagc tgtcactaca acgattggtt tagttgtttc
    46861 aatatactca ttttttccaa aaccatcttc tgagacgatt ttttctacgt tgactggata
    46921 gtcttcgatt tctgagtgtt tatagacctt gatgtttcgt ctttctagtt tattgataaa
    46981 gactttcgtg gcaggctgtc cactatagcg agtgataacg acactgttga ttaataagcc
    47041 ataaccacgt aattcatcga ttaaccgcaa gatatccata tcataagtaa tcccataatc
    47101 accacggatc ttattacgtt caatatctcc agcatagacg caaatcagta tttcagcttg
    47161 atctttcaat ttttgcagca atttgatttt cgcatcttct tcaaatcctg gaagtacacg
    47221 tttcgcatgc ttgtcgtcaa ctaacttccc accaaattct aaatataatt tgtcatagtg
    47281 gttcactcgt tccaaaatat acgctgactg ctcttcaata tatttttctg aatcaaaacc
    47341 aatttttttc actaggttcc ctccttaagt actaaagcat tttttcattt ttttgaggat
    47401 tcgtcaactg gaagagcgaa attcctcaaa aaaacaaaga aaatggttta aaccaacttg
    47461 tctagatagt tattcattgg tatgatagtt tttgataagg aaggtgctac atgaaaaaaa
    47521 gacagaaaaa gaaaaacgca tataaacact atatccgttc gatttttacc ggttatgaaa
    47581 gaatgcttga agatcccgaa ttggaacaat tgacgtttac ttatctaaac gaagaaacgc
    47641 agctaactcg tgatgagcat cagcgcattc atttcacaac aagagatctg cctagtaaat
    47701 aaaaaataag ataaaggtca tcggattcga ttctgtccta tcagatggaa agactagttg
    47761 atcgaaaaaa aggctgtacc aaattttggt gcagcctgtt ttatggagca ttgcccgctc
    47821 ttttttataa caatttttta cagaaaatgg tactattgaa gtattaataa gtgaaaaaca
    47881 gatgagtaag aggaggcaag tagtatgaaa gagccagata caaatgcaaa ttatgagcca
    47941 gacgaactag aggagacgaa cgcggatcag gatacaggac aagaatcgtc ttctttttac
    48001 gatatcaaag aaaaagcaag catgaatctt tcccaattat tagaagactt acaggctttt
    48061 gaaaaagctg tccgcgaaga agatatccct gagatctacc gtttatacaa tggccgattg
    48121 aatgaagaat taaaaagaag ctcaaatgaa aatcacgaga tcgatcaatt gctgatgcgt
    48181 aagatccatg atcgtttttt acaggaattt ccttttatgg aacaagtaga aaacatctcg
    48241 ccaacgatga gctattacaa aatcggcact tattaccatg atcggcccac ggtcggtatt
    48301 gatgcaagtc tgccagaaat ttttgttttg cctaagatcg atgaagagtg ggagaaatat
    48361 tcccaaccgg agtcaacgga ctatgacaaa aaaatcaatg agctagacgc aaaggtgatc
    48421 actgctcaga cagaaattga acgtttagat gaacaaataa aagaaatcaa tcgacaaatg
    48481 actgatttga acgacaataa aggattcttg aatcgtaaaa aaatcgagga agaaattcaa
    48541 gaattagaga agaagaagca agtactatct aatgaaaaat taggctggct tccttatatt
    48601 gagacgcctg aaacaatcca gcagcaaaaa gaagcattga agcaagaagc aagagcagac
    48661 cagcttcgtg cagccatcgt agaaaaagaa caaaggcaaa tcagacgcta tttcggtagc
    48721 aaagagggat tcggtcaagc aatccatgaa ttcttgatga attatcttgg caatgagaat
    48781 cctaataatc aatctaatga aggaggttcc gagtatgaat gaacacgatg aagcagaatg
    48841 gacaaaaaat gaagaacaaa cagaagatca tgaagaaacg aacacttcat tggaagaaca
    48901 aacaagtaat cctctggatg acacagaaga aatccctatg ctagaggaaa caaaaataca
    48961 tgaaaaagaa aaagtaactc cgacgaatac gaatactgca gaaaacaccc atgcttacga
    49021 aataactgaa aatcccgggt atttagaagg aaaagagcaa gatcatcaag atatcgtcag
    49081 tttgattgaa acagcggaag cagaattagc ggatttacgt atgagaaaag atttgatcga
    49141 atcagatttt ccacaattat tagaatcata tgatcgtttt atattgaatg aagaaccaat
    49201 ctccacgatc ggaaagacaa gcctgatcga atacttcacg tatgaattac tgaaaccgtt
    49261 gaatgatatt ggtctggaac ggtcaaattc agcttatgac acatggaaaa caagacattt
    49321 ttcgatcaat tatacgttga atggacaaaa cgaattagtc ttttcctttg tattaccgac
    49381 catcgatcaa cgataccaag tggaatcgat gagtctccta aacgtatcac cagagacaat
    49441 ggaaatcaat gtccaagatg accgggtgct ttctttgatc cgacactggt cagtggatcg
    49501 agtattctct gcagggcaga tcacgatatt caatcacaaa ttgaatcaat tattagccca
    49561 tgcaagaaca cttggtttta ccgttaatca gacattacta gacaatacga agccacttcg
    49621 tttgaatctt cagagcgaat ttgaattgac gaatgaagta ttggatgata tttttatcgt
    49681 ggcaatgaaa aatccatcct acgatatgga aaagatcaac gaaactactt atcaagtacg
    49741 attagataaa ggacagtctt taacgataac aacaaacgaa aaagatcaaa cagtcttgtc
    49801 gatctcatct ggagactacc cacgatctgt cattgatttc tttatcaatt acgaattctt
    49861 ggtcccatta atggtgagaa agtcctgatt ggataagttg gattaccaga tgtcattcag
    49921 ataattctgt tccaaaggac ttgcggcagt tatccagaat aattgtcaca agtcttttct
    49981 gtatgtacta aatggacgtg aataacttgc tgatgaagga gggatttcat taggaatgtc
    50041 cacaaataaa atagcacagc ttagcttatt gtctgctgct tgtgtagcag gtaggatcgc
    50101 ttttcaattt attccgaatt tccagccaat gactgctatt tttttattta tagtacttta
    50161 cttaagctta aaagatgcgt taattgtcat gagtctttct attgcgatca gcagttttta
    50221 ttttggtgtt ggaccatggg tcatcggcca atggatcagc tatactgttg ttctgagttt
    50281 gttttcaatc gtctgcttga gaaaaacagt gcaaaggaat ctatggttaa agggagtctg
    50341 tttttttctg gcgggcatgg tttacggaat aggtatgacc gtttttgata cgctgttata
    50401 tcgtttgcct caaccttgga tctattacct tcaaggggtg tcgtttgatt tgatgcacag
    50461 tataggcaat gttgtgttct ttcttgtttt tctgccagtc gtcaaacgtt tttacaatca
    50521 ttcaggagga aaaaatgaaa aaaataattt atagtttgct tgcaatgagt gtcagtatac
    50581 tcattttgac aagttgcagt acaacctata cacaatcggc ttccaaccaa aaggaggaag
    50641 taaaaacatc gcaaaaagca acaatcacgt tacaagaaaa tggtcaaaac ttttcggaaa
    50701 aagaagtggt cttcaaaaaa ggcgatgatt tactgagtat tttgaaacga aattttgaag
    50761 tcaaagaaga taacggcttc atcacttcgc ttgaagggca ctcacaggat gagaaaaatc
    50821 aactctattg gatgtttact gtggacggga aaagtgctac tactggtgcc aaagagatca
    50881 aattgaatga tggacaatcg gtcattttca atttgtctaa actataagtt tcataaaaaa
    50941 ctgttaaagg gcgaatattg ccataattca gtgagttcag ttgatgaaag aaggaaaata
    51001 acatggaaaa ttttaaaaaa agcggaatgt tttccgtaat tgctgctcta ggggctaata
    51061 ttctagttgc tatcagcaaa tttgtcggct atgcaatcag tggcagtgcc gccatgctaa
    51121 acgaaagcat ccacagtatc gttgattgca gcaatcagat tttgctgtta ttcggtgata
    51181 aacaagccaa taaaggacag agcgagttgc atcaatttgg tgaaggacga gcaaaatact
    51241 ttttcagtac aatcgtcgca atgatgcttt tcttcggcgg tggggcactt ggggtgatgg
    51301 aagcttttga aaagttgacg catccatccc atgaagtggg taatccgatc attgttatag
    51361 caatactgtt atttggtttg gtaatcgaag gaagttcgtt acgcgtggca atgaaagaaa
    51421 tcaaagaatt gaatactgaa aaactttcca cgatgcgctt tttgcgcgaa agtcgacaca
    51481 gtgaaatact gattattttt acggaagact tgtgtgctgt aatcggtttg gtcttggctt
    51541 tagcaggaac aatattgact tatgcaaccg ggattgctgc atttgatgcg atcagcggat
    51601 tgctgatcgg tttcttgctg atgggagccg ccattttcct agcaaaagaa ttttatagtc
    51661 tgatcatcgg tgaaagcgtg acagcaagcg atttatcaaa aatcaagtta gcttttgaac
    51721 gtcctgagat cagtcggctg atcgatataa aaacagttca tttaagtcca acggagattt
    51781 tagttgcagc aaaagcagat atcgttggta acaaagagaa tgaagcttac tcggtcatca
    51841 atgatattga aaaaaatatg cgtcagtctc ttcctgacaa gaagatgtat atatacattg
    51901 aaacagataa atatgaccca aattattctc gtaaataaaa cgtttattca tgaattgaag
    51961 caaaaatgag aaaaatataa tcttgttttt aaataaaacg gctacaattt agcgaattta
    52021 tgttacaatg agtccgctgt ttatttgttg taattaaagg agatatttta atgaacaaaa
    52081 agaaaagtgc gccatggctt caagctttgc atgcagtgat gccactttgt ataagctata
    52141 taccagtagg attagcttgc ggagtattgt tgcaaaaagt tggatttgat cctctcttat
    52201 caggactgtt atcgattctg gtcttttccg gtggcgcgca gtttttagtt gcatctatgc
    52261 ttacgacgca agcatcattt gcaacgacat tattgatggt tttcttttta gaattacgct
    52321 atacattatt aggagcaagt cttgccggtt ttatgaaaaa agaaaagcgg acgtttttgg
    52381 ctgtcttttc tcaatcactg aatgatgaaa actatgcggt gaactactta aagttttcaa
    52441 ctgacccttc ctggaataaa agaaaggctt tatatgtcaa ttggttctca atgactgcat
    52501 gggccggtag caatatgatc ggtaattttt tcggctcggt gattcgagta gatgctgacc
    52561 ttgtccattt tgctttgacg gccatgttca ttttcatgtt tatcatgcag atgaaaagcg
    52621 cactactgat ctttacaggt ttattctcag gcgtattagg ggtcgtattc atggtattat
    52681 tccaaaatac tttcggattg attgcagcaa cagtcattgc ttcatttgcc ggatttatgc
    52741 tggagaaggc attcaaaaaa gaaaaagcta agaaactaag agaccgcggt aaagatgtca
    52801 atgagccgct cttcaacttc ccggaacagg aggccaatca ccatgactaa actatatttg
    52861 ctacttttag ttgcttgtct gttcatcgtg gcatatatcc cgcgcttgtt cccgatgctt
    52921 tattttactc atcgaaaagt gccatcctgg ttcagtgact ggatgaaata tgtaccggtg
    52981 gcattatttg cggcgttagc ttttaaagat gttttcatta ctcatgaaca tctggatatt
    53041 gcttggaata tcaaaatagc tgcaatgatt ctagtagcag gcgtggctta caaaacacgt
    53101 tcgatggcgt tgtcagtttt gacaggactt gcgtctgtct ttttgctgtc tatgctttaa
    53161 actgttttat tttattaaaa acagagattg cgacataagt tgttcaaact gatctatccg
    53221 aactgcattt gcaacagtca attctggatg caagtttatt cgtagggata aaaaagatta
    53281 gtgttggctt atgatgcaag ctctttttta ttttaggaat tagagaggga tttgtccttc
    53341 tatgattttt tgctataata gggaagatgt ttattttatg aaagaatagt tgagggaatt
    53401 taaatgaata aaaaattgat gcaaggaaca ttttggctaa cctttgctaa tcttctatgt
    53461 aaagttttag gggtagtcta tttgattccc tggctaagta tgatggggaa caatcaagat
    53521 ggtatgcttg ctacgacatt gtataatgtt ggctatcttc cttatggatt gttcctgatg
    53581 cttggtacag tcggatttcc aaatgcgatt gcaaaaaaag tagctgtagc cacaaaagaa
    53641 ggagataacg ctgcttgtcg gctgattttt agaagtacga tcaatatcat gtttgtcatc
    53701 ggtatcgcct ctgctgcact gatgtattta tttgctcctt tactagccgg aatcagtccg
    53761 attgctaacg ttaataatgg gatactagct atcagaagtt tatgcccatc tttgattgct
    53821 atcccaattc ttagtgcaat gagaggatat ttccaaggaa aaaatgatct gcggccttat
    53881 ggaacttctt tgattatcga acaggctgtg cgagtgatcg ttatcttggc tggtacttat
    53941 tacttgcgcg tattgactga cggaaccata ttagaagctg tattgatcag tacagtcgct
    54001 tctttcttcg gtgggttagc tgcgattatc catatgtata tcgtcggacg cagaaaagac
    54061 ttcttcgaac ttaaagattt tttgatttcc agccgttatt tcgaaagaga aaaccgatct
    54121 gcctctgtct ctatcattcg ggaaacacta ccgtttattt ttgtcggctc agtcattact
    54181 atcgttcaaa tgatcgacca agtaacgatg aaaccactgc ttcacttttt ccgtccagag
    54241 atcgcagatc agcaactgga attcttattc agccgtgctt ctgtcaatcc aaataaattg
    54301 acattgatcc tgatctccat ggtaggaaca gtagctataa gcagcttgcc aatattaagc
    54361 acgatgaaga aaaaagatcg gatacaaatc gaaaaaacag taggagatag tttttcgatt
    54421 gcgttattga ttcttcttcc ttcattgact ggaatgtctt tattagctgg accactatac
    54481 acattgtttt ttggctatga tcctgaaagt gtcggatatt tccaaatggc tttgctagct
    54541 tctttgtttt tctctttatt cacgatccta tctacgatgc ttcaatcttt gaatcaccat
    54601 cgttttgcga tccgattaac tgtagaagca attatcctga aagtcatctt ccaagtaatc
    54661 ggattaggat tagttggcgg atacgggatg agcttatcaa atggcttagc attcggtatt
    54721 gtctttgttc gcggctatca ctttatgtgc aaagaatacc gaatagcacc tttagcaaag
    54781 atcagcaatt ttttcttaaa aactttccgc tccaccctga ttatgcttgc agtatgtttt
    54841 gccgttttct ttttgctgaa tcagcgattg tcaatggaat caaaaagcta tgcaatgatt
    54901 tattgtgtgg ctgtaggaag tattggcggc ttagtatttt tattttctca attcggaaaa
    54961 aatgggtttc gaatgttgaa aaatgttaaa catcatagca gaagcaaaga ataggttaac
    55021 taatcgtttt ttgctgtcac ttgaaaaacg gcaactcgta tgattacgct tgtcgttttt
    55081 ctattttcca attttagttt catatctaat cttacttatg atatagttat aaggtctgga
    55141 aaaattcttt gaaacgagga aattaaacac atgaaacttg cagtagttac agatagttcg
    55201 gcatatctgc cggaacgtat caagaaccat cccgacttat tcgttattcc aatccctttg
    55261 attatggatg ggaaaattta taacgaagga atcgatatcg aagcggatga atattatgga
    55321 cttttaaaaa acagtaaaga ttttcctact acttcacaac ctgtcgtagg ggaagttttg
    55381 ggtttatatg aggaattgaa agagaaaggg tatgacacga ttttaagtat ccatctttct
    55441 tcagggattt ctggctttgt caacacatta tttgcgatga aagatgacat cagcggagta
    55501 acggtcattc cttatgactc taagatcact agtatgccga tgggacacat ggtagaagct
    55561 gccttagact taaatgatga aggtcagtcc cttgatgaaa tacttgcaca tatcgatcga
    55621 atccgagata atacctacgc ttatctgatt gtagatgatt tgaacaattt agtacgagga
    55681 ggacgtttga caaatggtgc agcgctgatt ggcagcttat taaaaatcaa accgatcctg
    55741 acattttctg aagggaaaat tgttttattc gaaaaaatcc gttcaagtaa aaaagcattt
    55801 gctcgagctg aagaaattat tggtagaaga aataacgaaa tacaaccgcc agtcaaactt
    55861 tacgtgatac atgcaaataa tttagaagta gcgattgcgg agaaagagaa attgcagaaa
    55921 aaatatccaa atgcagaaat cgaaattggt catttcggac cagtcattgg tacacattta
    55981 ggtgaaaaag ccatcggcat tgccatttca gcgcaataat tccttttatt caaaaaacat
    56041 accaaaaata ttccaacatc atcttggact ttctacatgt tactaatgag cgtgtaaaag
    56101 aacgagatgg tgtttttatt tctatcaatg aagctctttt tctttgcaat cctcacttca
    56161 atcctctata atgtcgcata tagtttagta aatgagtaaa ctactaattt acttatttac
    56221 taaaaataaa aggatgagga gttaaaataa tggaaatacc aacaaattta aaacataaac
    56281 cagtaatcgt tgtagaagac tatgataaag ttgatggaag aaatgcatta aatacggatg
    56341 caaaagggct ttcactgggc cttgctcagt ggaatgatcg tggaaaagtc gatatctcag
    56401 gcaaggtatg gcgacatact ggagaaaaat ggtcacgaca gtcggaagaa ttaccaatca
    56461 cacgtatttt agatttagcg atcttagctg cacaaggaag tttatacttc caagatgctt
    56521 atcgttatga aaaattttat gatccagaaa atccagtcgt agacatcatt ggattacaag
    56581 ggaaccgaat gacggtagaa gtagatacca aaaatccaaa gatcgatgaa gacatcattt
    56641 tgtattacga tacactacaa aaagacggag aactgattgg ggaacgattc cgtattttaa
    56701 aacgtctttt agatgagcta ggatattaat agacagagat gatcaaaagg ggaagagaag
    56761 catggagaat ttctcactaa cagaaaaccg aaccttttca cggctagaaa agcaaatgat
    56821 ctggaagaaa ccgaaaagcc atcggacaag tgcagaagaa tggcggatcg cctccgaaat
    56881 caaagggaat tggcaagatc ctgaaatgaa aatcagtaac gtacttttgg aaggagatgc
    56941 cgggtcgggg aagacacaat tagccaaagc actatctgct gatctgcaac ttccctatac
    57001 aaaagtgacc tgttttgcag atatggacaa atcagatgtt ttcggagcct tattacctgt
    57061 agtagattct aataaggaac aagaccaaga attactagaa gctatttacc aaacagatac
    57121 acttgaagct gtactgacac tgatccagaa ccattacggc attgatcctt tttctgctaa
    57181 agaaaaatta gcagagctag ttcaaaggat cgaagctgat tatccagatg caatccatta
    57241 cagctattac ccttctgaaa tcgttcgagc gattgaaaaa ggatatttat tagagattca
    57301 agagccgact gtcatccgag atgcctctgt tcttgtggca cttaactcag cgctcgaacc
    57361 aaatgggatg ttgaatttac cgacaggaat cattcgtcgc catccagatt gcgtcattgt
    57421 gatcactaca aatcgaaatt accaaggaaa tcgcccatta aatgaatctt taagagatcg
    57481 gatgcaacat gcggaaaaaa tggatcttcc tgccttagaa gtcatggcag aacgtgcgat
    57541 ggcgaaaact atgatccaaa aacaagaact tctcttaaag atggcagaga ttatccgttt
    57601 gttggatgaa actgcaaaag ctaacgccat caaaggtgta gcaggaatgc gttcttattt
    57661 ttattgggca aatacctata agcaaggaca agatttactc cagtcgattt atccaaaagt
    57721 tttgtataaa ttatccactg attcagatga attggcaatt cttgaacaag ctttgtctga
    57781 cagtggattg ctactggaac ttcaggacat attgagaaaa gaaaaatggg gtcatcctca
    57841 atctgagcat acaaaaggaa gaaccattag cgccgaagaa gcaaatgaac gaaacatcac
    57901 tgaaaatgct gaagaaattc tgcgcttaga tgaaaagaaa tcgttgtctg ctgaagaacc
    57961 aaatgaggga gaagagaaac aagaagaaac aatagaaaaa aacgagattc ctcctcaaat
    58021 gcaaaaagaa cgcagtagcg atatcgaagg aaaaaatcaa aaagaacaac aaacaggaga
    58081 tgattctcaa gaaatgtctg cttctgacat ggaagcacat gataaggaaa tcaagaagca
    58141 actgaataaa gaagcgcgac aaatcatgaa ggaaacgatt catgaaaaag aaggtctcat
    58201 cgttcaccga ccagctttcc aaggaaaaac gccggaagca cgtgagctac acatgcaagt
    58261 aatgccaata gtagaatcac ttagccggca aattttagag ttactggata atgaacaaac
    58321 agagacgtac caaaaaggaa aatacgaagg tcagcggttc aatgcaagca aagtagcata
    58381 tggtgatttg agaaattttg acaaaaagaa cccgccacat gagcaacctt ctttagcggt
    58441 agctgtacgg atcgatgaat ctgggtcaat gatacgggat gatcggatcg aagcggcaaa
    58501 aaaagcagcg attgccattg ccgaattttc taagaaagtc gatatcccat tgttgattta
    58561 cggagataca gcagaccgtt cgtcaagaga aaagacttct ttgttttctt ataaagaatt
    58621 tgaagacgga tttcaatggt taaatgaaaa attagtcact atgaaaccaa ggcaaaacaa
    58681 tcgtgatggt gctgcacttc gtttagcagc agaaaaatta aacagacaat ccgcaacaac
    58741 caaactgttg cttaatatta gtgacggtca gccaaaagcg ttgccggatt atacaggcaa
    58801 aaaagcaaaa gaagatatcc agtctgtttt gaaagaatat gaacgtcaag gaatcctatt
    58861 tgtctccgca gctattggcc aagacaaaga agaaatcaag tcgatctacg gtgaaagtcg
    58921 ttttgtagat attactgact tgaatgaatt tcccaagcaa atgattcaac tgattgcccg
    58981 ctatctatga taaaataaag ctcaacgaac gcacttagca gattcgttga gcttttcgtt
    59041 tctagttacc ggtaacaagg atacttctaa aatagaatcg gttataatca agagggaccg
    59101 ttaaaggagt gaaacgatat gatacaagaa caaaaatggt ggaaagaagc agtaggctat
    59161 caaatctatc ctgctagttt caaagatagc aatggcgatg gtcaaggaga catcaatggg
    59221 atccgtgaaa aacttaatta tttgaaagat cttggtatcg gctttatctg gatcaatccg
    59281 atctatcaat ctccatttgt cgataatggt tatgacgtaa gtgactatca agatatagaa
    59341 gagagattcg gaacgatgga agattttgat ttattgctaa aagaagcaca tgaattaggg
    59401 atcaaagtga ttatggatct tgtcatcaac catagttcgg atcagcatca atggtttgaa
    59461 gaatcgaaaa aatctaaaga aagcccgtat cgcgattatt acatttgggt cgacggggta
    59521 gatggcaaag aaccgaataa ttggacatcg attttcggcg gttctgcttg ggagtattct
    59581 catgaaactg gacagtatta tctgcatgtt tttgcaaaag aacaaccaga cttaaattgg
    59641 gaaagcgaga aattgaaaga agaactattc aatatgatcc gatggtggtt ggataaaggg
    59701 atagatggat ttcgtttaga tgcgatttct catgtaaaaa aagatgaata ttcagtaaaa
    59761 gccacagaga accctttctc accctttcaa aatgtctcag gaatcgaaga acatttgacc
    59821 gatttgaaac atgtttttga agagtacgat atcatgactg tcggagaagc aagtggtgtc
    59881 actgcagaag aaggaccaca atgggtaggg aaagacggtt atttcgatat gatattcgaa
    59941 tttgatcata tccatatctg gcagcaagaa aaagaagggc aattagatgt ccttaaattg
    60001 aaacttgcat taagcgcttg gcaaacttca ttggatggta tcggatggaa cgctttatat
    60061 atggaaaacc atgatgttcc tcgtgccgtt tcagtgtttg gagatactcg tcccgatttt
    60121 tgggctatgt ctgcaaaagc aatcgctatg atgtatttct ttttgcaagg tacgccattt
    60181 atttatcaag gacaggaaat cggaatgacg aatatgccct ttgaatcgat cgatcaagtt
    60241 gatgcagtag attcgaaaag actttataaa aggctgcttg cggaaggtaa gacaagagaa
    60301 gaagcattgg atatcattcg tgaaacaacg agagacaaca gcaggacacc catgcaatgg
    60361 acttcggaac aatatgctgg tttttctaca catgaacctt ggctgatcac taatccaaat
    60421 accaaaacga tcaatgtaga acaacaagaa tatgaaccag agtcggtcct gcaattctat
    60481 aagaacatga tccgcattag acaaaccaat aaaggtctga tatacggttc ttataaagaa
    60541 tatcttcatg aacatccaca actttatgtc tatgaaagat atttagaaga tgaacaatat
    60601 cttattatgg taaacttaac agaatcactt gctgactatg aacttccaaa agaagcagat
    60661 cagtcctgga cattactctt gtcaaattcc tctagcggag aatttgaagc taaaggcata
    60721 ctagcacctt atgaagctcg gttatataaa acaaacaagt aaaacttcct cgttaaagtt
    60781 cattagttgg actttgcgag gaagtttttc agattgctct gtcaattact catttcaata
    60841 attcgctcta ggaccaccga tatatttagg acgagagcga agggctgtca cgtgagcttg
    60901 tccaagggtt ttcaaacgag gtctgacagg tacttggaca tgtttgatat gcataccgat
    60961 tgatgtgtca ccgatatcga taccggcttg tccaactacg tgttccactt cgacaggatc
    61021 attgaactgg tcaaaagcag caacagaaca agcacctcca gcatgtagtg caggaacaac
    61081 agagacaatt tcgaaatttt ttgcttctgc cactgttcgt tctactacta atgctcggtt
    61141 caaatgttca caaccttgga cagctagcgc aatttcttta ggatccaaca actcttttaa
    61201 cgtacggatg atccattgac caacttccgc actggaattt tttccaatat gtcctccaac
    61261 gacttcgctt gtgctgcatc ctaaaacaaa aagatcacct tttttcaagt gtgcctcagc
    61321 caatatgtca ttaactattt cagtcaattg gtcttttaat tctttttctg acaacttcat
    61381 tttctaaaac cttctttttc aattaatatt gcttccgtgc ttgaatacgt tgaagacttg
    61441 cagttatagg aaaggcaagt cccattccaa tcagattttg gaagatgttt cctggtatag
    61501 aagccactcc agccggccaa tcatataaaa tccaaccggc gataccatag ccgatgatca
    61561 taactaagct tcctaataaa agccctaatc cccacatacg agtagaagat ttgctgaaag
    61621 aaccagcaac atatccttgt aacccgtgga tcactaatga aaaaactgcc cactgcggat
    61681 atcctgaaat caaatcgatc aatagaccac tggaagcacc aacaactaat ccacccgttg
    61741 gaccataaag aaaagcagcg gtatagatcc cggcctcgca taatgtcaca aatccattcg
    61801 tagccggtac agggatcaaa attgttaatg aaagggcaac tgtcaacgca atcagcatag
    61861 catagatcgt taattgctta gttttcattt ctcattcctc ctttttgaat accgccagac
    61921 cagacacttc cggtatgatc gttcatcagc acgccattag aaatacaatg ggcaacaaat
    61981 tttttacttt ctgctactgc tttggtaaaa tctgccccta acacaagatt cgctgttatt
    62041 gcagaagaaa aggcacaacc ggccccgttt actgttgtag tgtcgatttt tttatgagaa
    62101 aatacctcat aatgatcaat tgaatagaga agatccacag cttcatctcc agccatcctt
    62161 gtgccgcctt tgatcacaat gttttttgtt cctgaagcag tgagttcttt agcgagatgg
    62221 atcatttctg ttaacgaaga gggaagagct tgaccagaaa gtaaagcagc ttctgccaaa
    62281 ttaggcgtaa tcatcgtaac aagtggaaaa agttcttcga tgagctgcga aatatacaat
    62341 tgattgatca cagcttcagt ttctttgaat gccaaaacag ggtctaaaat gattgggata
    62401 ttttgttttg tttttatgaa gtctcgaaca accatgattg cttcacttga attcaataac
    62461 ccaattttga taccatctaa tgaagtcatt ttatcaatcg aaactaactg tcgtttaagc
    62521 aattccaaag atatagattc cagcataaat cgctcattaa tatctagtgc ccctatagaa
    62581 gtcaaggcgc ttagtccgaa tagaccaaaa ttctcaaaag tttttaaatc tgtttggatt
    62641 cctccaccag caaatggatc agaaccgcca attgtcaaga ttcttttcat aacattttcc
    62701 tccatgaata agagtataac gaaattttca aaaaagaaaa acagccaatt ggcatatttt
    62761 tatctcatcc aatttaaaaa aacaaaaaga aaagaaagac caaaatggat ctttctttcc
    62821 ttaaatagtt aggacttttg tgattttaat tctttctcga tttgaagccg ttgcactttc
    62881 attgtagctg ttcgcgggat tgcatcaaaa tcacggatga tagggacgtt caagcgagga
    62941 agttcatgga cttgctccca ccatcgattc caatccattt ctttatcagg agctaaagca
    63001 ataatcggtt gtggagaatg atttttatcc cttacaatca ctacttctgc caaaaaatct
    63061 aacgaatcta ataaaaagtc ttcaatagct aatgtactat tgatcgtttc gatcaaatcc
    63121 acttgccgat ctttcaaaaa taggtggcca tgcttatcca taaaaccgta atctccgcta
    63181 tcccaccaat cgccataaac attttcctgg aaccgtgcat cttccttgta ataagtcaaa
    63241 gcccgtcctt tagacagtaa ttgtatatga ccatctgtgt tttcaggtag gacattccca
    63301 actgaatctg taatccgagc gcttgtcatg tcttccagtc caacgcccat atctcttgca
    63361 tcacttgttt tcaaactctc tagtgtatga gccttaagaa tcattggtcc gcattcactt
    63421 tggccatata cttgaagaaa taccgcatcc tgtgccatcg acgttcgcaa aaatgtcttc
    63481 attgtctggt tgtttatagc atcaaaagtg gagtgatagt atcggatacc cgaaaaagct
    63541 tctggatgct ccttagcagt aaaacgccac tgaacaaagt tattcggatg ggtctctagt
    63601 gcaattggcc ggtgagcttc caacatatga acaacttttg aactttgtgc gtttgctaaa
    63661 ggcatcatag gaaatcccat ggacatcaaa gaagagatac caatattgaa tctggaatgc
    63721 actggagaga tgtgaaaagc gattaatttc ttttccgaaa tttttgtgaa aactgttttt
    63781 tgccatttcg tccgccatcc catagaatga gcagaatgac aaataagttt agggatacca
    63841 gttgtaccag aagtatgggt catataagaa atttcatttt tgtctaaaaa tgattgagaa
    63901 acagacaaag caggttgttc cattaaataa agaataggaa tctgttttga ttttgttcca
    63961 tttgaaattt ctctcactcg cttttttgtc tcatcatcaa ataaaatgaa agggtcttct
    64021 aaacgatcga taaatacttc cattgttgtt gttggtagat gataagaagt catgacaggc
    64081 actgcaccaa ggtaagacac agaaacagct agaaggtatg tgtcaaaagc ggaactctta
    64141 taaataataa ctttgtctcc ggatttcact ccaagatgag ccaattgata agcccgtttc
    64201 aacacacttt cgcagcattt tttgtaagtt gtttcaagtc ctaattctgg gaaagctgaa
    64261 agtggctcat caaagataat cggggtctcg gaaaagttag ctgcagcttc ttgaaaattc
    64321 gtaaataagt tcaaagggga atacgttatg gtctccatca ttcacactcc attatctttt
    64381 gttaagtaat atacaaattc aagataatcg taacataatc ctttatataa taacatagtt
    64441 tattgtgaaa aaaagatcat acatttgttt tatatggaag aaacccgaac gaatgccgct
    64501 aattcgtgat aagaaaaatc aaccatcttt tcccagatat cttgaaaaga atgggatgag
    64561 aggtatcgat taccacataa ataatttacc gcgtcagcat catctaaata tagttctgca
    64621 taataacgat atgtttttct gcatagttct ggcgatacgt ttttatatac tgtaattttg
    64681 ctcaaaattt ggcgaatagt ccgaggagaa atttgctgat catgtgagga acgaaaaaca
    64741 aaagaatttt cgtccgtatt ttgtgctgtt aacttaaaat agttctccag aaatggcatc
    64801 gcttcttttg gtattggtac tttattcagt ctgttttctt ttctattcag attaagaatc
    64861 tgcttggtca aagatacatc tttacgttta agttctacta cttcatggat ctttaatccg
    64921 caatacagaa gaatggcagt aattgcaagg ttcctcggtc tattcttttc ttcaaagcta
    64981 gcttctctgc ttgtttgaaa gccttcaatc gggataaaca aatgctcaaa atctttgaaa
    65041 agttctgcat cgatatatcg cggagctgct ttggttgttt ccggtaaact tgtacccaaa
    65101 agagaaatct cttcttcaat cagtcctttt tgatacaaaa atcgtaaaaa atgatttaat
    65161 gaatattgct tccttgaaat cccgtaatag ctattttcaa acaattgctc cgtttcttgg
    65221 ttcgctgtag tttggaacga acgagtatgt cgatagattt tagctaagaa attctgataa
    65281 tcttgttttt ctaaatggat aatcagctga tcatccactt cttcagaaaa tacttttctc
    65341 aaataatcag taaacagatg aaaatctttt gcgtattcat agcgactgcc taatgaaagg
    65401 gaagaacgat tttcttctaa aaactgttga aagacggaag ggagcaagtg tgtacgttgc
    65461 tttaactttt cttgcagttg ttttctagtt ttgctgtcca ttacaaattc cctccaatag
    65521 tgttcatttt ctatatttta ccgcatttca tcaaatgaag atagacagtt tgtcttgatc
    65581 ttaggaagca aatttttaac taagtactag ctaaaagata tgaagtaaga agatacattt
    65641 ttagttattt tattagtgca gtcattcttt tgatctttta attgatttat cctcttttta
    65701 gctatgtggt tacttcatga gcaatgaaat ggatttggtt cgttctaatg gcaggaggct
    65761 ctttctttta tttccgaaaa attagaaaac attttttcag aatcgattgg ctctccattt
    65821 attcaataat ggtttgtcta acgatattgt tgggataatt cttaaagaag tattagaaat
    65881 agttggtact tcattacttt acatgaagat ttattctatg gtaggagcaa ttatattgag
    65941 aattaatcct tttttatata agttgtttgc ttattgatgg attgg
//
LOCUS       DADVXM010000008        58991 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.008, whole genome shotgun sequence.
ACCESSION   DADVXM010000008 DADVXM010000000
VERSION     DADVXM010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 58991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.008"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(59..187)
                     /locus_tag="KB927_000594"
     CDS             complement(59..187)
                     /locus_tag="KB927_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBB6839534.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="KB927_000595"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="KB927_000595"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBB6839535.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="KB927_000596"
     CDS             complement(1674..2729)
                     /locus_tag="KB927_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBB6839536.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="KB927_000597"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="KB927_000597"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBB6839537.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="KB927_000598"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="KB927_000598"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBB6839538.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="KB927_000599"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="KB927_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBB6839539.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="KB927_000600"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="KB927_000600"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBB6839540.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="KB927_000601"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="KB927_000601"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBB6839541.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="KB927_000602"
     CDS             10491..12050
                     /locus_tag="KB927_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBB6839542.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="KB927_000603"
     CDS             complement(12161..14092)
                     /locus_tag="KB927_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6839543.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="KB927_000604"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="KB927_000604"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBB6839544.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="KB927_000605"
     CDS             complement(15021..15773)
                     /locus_tag="KB927_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6839545.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="KB927_000606"
     CDS             complement(15932..16141)
                     /locus_tag="KB927_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839546.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="KB927_000607"
     CDS             complement(16152..17480)
                     /locus_tag="KB927_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839547.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="KB927_000608"
     CDS             17616..17771
                     /locus_tag="KB927_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839548.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /locus_tag="KB927_000609"
     CDS             complement(17845..18432)
                     /locus_tag="KB927_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBB6839549.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="KB927_000610"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="KB927_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBB6839550.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="KB927_000611"
     CDS             complement(20012..21301)
                     /locus_tag="KB927_000611"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBB6839551.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="KB927_000612"
     CDS             complement(21455..22387)
                     /locus_tag="KB927_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839552.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="KB927_000613"
     CDS             complement(22544..23203)
                     /locus_tag="KB927_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBB6839553.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="KB927_000614"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="KB927_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBB6839554.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="KB927_000615"
     CDS             complement(24244..24534)
                     /locus_tag="KB927_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839555.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="KB927_000616"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="KB927_000616"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBB6839556.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="KB927_000617"
     CDS             complement(26821..28176)
                     /locus_tag="KB927_000617"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBB6839557.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="KB927_000618"
     CDS             complement(28200..29369)
                     /locus_tag="KB927_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839558.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="KB927_000619"
     CDS             complement(29366..30253)
                     /locus_tag="KB927_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBB6839559.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="KB927_000620"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="KB927_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBB6839560.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="KB927_000621"
     CDS             34320..34841
                     /locus_tag="KB927_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBB6839561.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="KB927_000622"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="KB927_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="KB927_000623"
     CDS             complement(36284..36940)
                     /locus_tag="KB927_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839562.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="KB927_000624"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="KB927_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBB6839563.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /locus_tag="KB927_000625"
     CDS             complement(38477..39475)
                     /locus_tag="KB927_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBB6839564.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="KB927_000626"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="KB927_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBB6839565.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="KB927_000627"
     CDS             complement(40491..41222)
                     /locus_tag="KB927_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBB6839566.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="KB927_000628"
     CDS             complement(41226..42491)
                     /locus_tag="KB927_000628"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBB6839567.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="KB927_000629"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="KB927_000629"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBB6839568.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="KB927_000630"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="KB927_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBB6839569.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="KB927_000631"
     CDS             47833..49335
                     /locus_tag="KB927_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBB6839570.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="KB927_000632"
     CDS             49337..50074
                     /locus_tag="KB927_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6839571.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="KB927_000633"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="KB927_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBB6839572.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="KB927_000634"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="KB927_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBB6839573.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="KB927_000635"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="KB927_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBB6839574.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="KB927_000636"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="KB927_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBB6839575.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /locus_tag="KB927_000637"
     CDS             complement(55574..56740)
                     /locus_tag="KB927_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBB6839576.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="KB927_000638"
     CDS             complement(56756..56983)
                     /locus_tag="KB927_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBB6839577.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57370..57626)
                     /locus_tag="KB927_000639"
                     /pseudo
     CDS             complement(57370..57626)
                     /locus_tag="KB927_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            complement(57969..58434)
                     /locus_tag="KB927_000640"
                     /pseudo
     CDS             complement(57969..58434)
                     /locus_tag="KB927_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323211.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
BASE COUNT        16244 a        12792 c        10267 g        19688 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacttgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc a
//
LOCUS       DADVXM010000009        56280 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.009, whole genome shotgun sequence.
ACCESSION   DADVXM010000009 DADVXM010000000
VERSION     DADVXM010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 56280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.009"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(43..1611)
                     /locus_tag="KB927_000641"
     CDS             complement(43..1611)
                     /locus_tag="KB927_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBB6839578.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(1615..2025)
                     /locus_tag="KB927_000642"
     CDS             complement(1615..2025)
                     /locus_tag="KB927_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBB6839579.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(2022..2945)
                     /locus_tag="KB927_000643"
     CDS             complement(2022..2945)
                     /locus_tag="KB927_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBB6839580.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(2942..3820)
                     /locus_tag="KB927_000644"
     CDS             complement(2942..3820)
                     /locus_tag="KB927_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBB6839581.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(3807..5144)
                     /locus_tag="KB927_000645"
     CDS             complement(3807..5144)
                     /locus_tag="KB927_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBB6839582.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(5147..6250)
                     /locus_tag="KB927_000646"
     CDS             complement(5147..6250)
                     /locus_tag="KB927_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6839583.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(6324..7832)
                     /locus_tag="KB927_000647"
     CDS             complement(6324..7832)
                     /locus_tag="KB927_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6839584.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(7798..8490)
                     /locus_tag="KB927_000648"
     CDS             complement(7798..8490)
                     /locus_tag="KB927_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6839585.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(8512..9486)
                     /locus_tag="KB927_000649"
     CDS             complement(8512..9486)
                     /locus_tag="KB927_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6839586.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            9786..10658
                     /locus_tag="KB927_000650"
     CDS             9786..10658
                     /locus_tag="KB927_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6839587.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(11116..13314)
                     /locus_tag="KB927_000651"
     CDS             complement(11116..13314)
                     /locus_tag="KB927_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6839588.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            13546..14538
                     /locus_tag="KB927_000652"
     CDS             13546..14538
                     /locus_tag="KB927_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6839589.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            14598..16019
                     /locus_tag="KB927_000653"
     CDS             14598..16019
                     /locus_tag="KB927_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBB6839590.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            16012..17511
                     /locus_tag="KB927_000654"
     CDS             16012..17511
                     /locus_tag="KB927_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBB6839591.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            17550..18944
                     /gene="uxaC"
                     /locus_tag="KB927_000655"
     CDS             17550..18944
                     /gene="uxaC"
                     /locus_tag="KB927_000655"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBB6839592.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            19103..19786
                     /locus_tag="KB927_000656"
     CDS             19103..19786
                     /locus_tag="KB927_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBB6839593.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            19788..20624
                     /locus_tag="KB927_000657"
     CDS             19788..20624
                     /locus_tag="KB927_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6839594.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            20635..22389
                     /locus_tag="KB927_000658"
     CDS             20635..22389
                     /locus_tag="KB927_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6839595.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(22665..23006)
                     /locus_tag="KB927_000659"
     CDS             complement(22665..23006)
                     /locus_tag="KB927_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6839596.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(23074..25245)
                     /locus_tag="KB927_000660"
     CDS             complement(23074..25245)
                     /locus_tag="KB927_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBB6839597.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            25414..26313
                     /locus_tag="KB927_000661"
     CDS             25414..26313
                     /locus_tag="KB927_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6839598.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(26384..27241)
                     /locus_tag="KB927_000662"
     CDS             complement(26384..27241)
                     /locus_tag="KB927_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6839599.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(27226..29928)
                     /locus_tag="KB927_000663"
     CDS             complement(27226..29928)
                     /locus_tag="KB927_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBB6839600.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(29941..31230)
                     /locus_tag="KB927_000664"
     CDS             complement(29941..31230)
                     /locus_tag="KB927_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBB6839601.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            31380..32426
                     /locus_tag="KB927_000665"
     CDS             31380..32426
                     /locus_tag="KB927_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6839602.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            32428..34581
                     /locus_tag="KB927_000666"
     CDS             32428..34581
                     /locus_tag="KB927_000666"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBB6839603.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(35054..36505)
                     /locus_tag="KB927_000667"
     CDS             complement(35054..36505)
                     /locus_tag="KB927_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6839604.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(36502..38226)
                     /locus_tag="KB927_000668"
     CDS             complement(36502..38226)
                     /locus_tag="KB927_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6839605.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(38219..38833)
                     /locus_tag="KB927_000669"
     CDS             complement(38219..38833)
                     /locus_tag="KB927_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6839606.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(39178..40635)
                     /locus_tag="KB927_000670"
     CDS             complement(39178..40635)
                     /locus_tag="KB927_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6839607.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(40676..41596)
                     /locus_tag="KB927_000671"
     CDS             complement(40676..41596)
                     /locus_tag="KB927_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6839608.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(41608..42555)
                     /locus_tag="KB927_000672"
     CDS             complement(41608..42555)
                     /locus_tag="KB927_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6839609.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(43034..43753)
                     /locus_tag="KB927_000673"
     CDS             complement(43034..43753)
                     /locus_tag="KB927_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBB6839610.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(43802..45448)
                     /locus_tag="KB927_000674"
     CDS             complement(43802..45448)
                     /locus_tag="KB927_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6839611.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            45627..46217
                     /locus_tag="KB927_000675"
     CDS             45627..46217
                     /locus_tag="KB927_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6839612.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            46309..47814
                     /locus_tag="KB927_000676"
     CDS             46309..47814
                     /locus_tag="KB927_000676"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBB6839613.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(47898..49250)
                     /gene="celB"
                     /locus_tag="KB927_000677"
     CDS             complement(47898..49250)
                     /gene="celB"
                     /locus_tag="KB927_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBB6839614.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(49250..49768)
                     /locus_tag="KB927_000678"
     CDS             complement(49250..49768)
                     /locus_tag="KB927_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839615.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(49784..50110)
                     /locus_tag="KB927_000679"
     CDS             complement(49784..50110)
                     /locus_tag="KB927_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBB6839616.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(50123..52102)
                     /locus_tag="KB927_000680"
     CDS             complement(50123..52102)
                     /locus_tag="KB927_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6839617.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(52123..52437)
                     /locus_tag="KB927_000681"
     CDS             complement(52123..52437)
                     /locus_tag="KB927_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBB6839618.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            52605..52898
                     /locus_tag="KB927_000682"
     CDS             52605..52898
                     /locus_tag="KB927_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBB6839619.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(52976..54088)
                     /locus_tag="KB927_000683"
     CDS             complement(52976..54088)
                     /locus_tag="KB927_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6839620.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            54475..54654
                     /locus_tag="KB927_000684"
     CDS             54475..54654
                     /locus_tag="KB927_000684"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839621.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            54848..55018
                     /locus_tag="KB927_000685"
     CDS             54848..55018
                     /locus_tag="KB927_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6839622.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(55442..>56280)
                     /locus_tag="KB927_000686"
     CDS             complement(55442..>56280)
                     /locus_tag="KB927_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6839623.1"
                     /translation="YQLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGV
                     VLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAP
                     TGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIF
                     LTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKR
                     NI"
BASE COUNT        16772 a        11512 c         9919 g        18077 t
ORIGIN      
        1 agtgaaaata agttagtgaa cctcatttat taaagaatta aattacagat gatcttttcc
       61 atcatacttg aaaaactcaa aatcagcata acttcctctt tttttattta gatcatgcac
      121 tgctatcccg ataaaatttc cagtaaaccc tcctgagagt atacacatgt ttttttgcgg
      181 acctactttc ttccattctt cagttgatac gtctttcaaa tgaaactgtg ctgtctcttt
      241 ctttacagtg actttcaaaa aagtcttctt ttctgtgagt ggaatcgtcc aatcttctat
      301 ttgtgctact ccgttttctg attctatcat acgtaggcat tttcccttgt cctcattcca
      361 agtaacataa caataaatat aattggattc atttaagtac agtaccagtc cagccatctg
      421 attaaaatta ttaggcatgt attcaaatgc tgtctccgca tcaaaagtaa aatccgtttg
      481 ccgaatagct aacaaatgat gttcgaaggt agattgaaga gattcaccgg aaatcagacg
      541 taaaaaacct ggtctacatt ttgtatcaca ccaatcagca tttggcaaaa tgcgtctggc
      601 attccagttc ttctttagct ctccttcaaa tgtatccata aactgatgat ctttttcttg
      661 ttgtacctct tcatttgtct caatcattat ttcttccatc ggagttgtct ggctatcttt
      721 aagtcttaac caatcgtcgg acgtccaata cacttcttga atagcggttt ctcttcccaa
      781 aatagccgca ccgtttaatg gtctggtaca aagatatgtc atgtaccatc ttcctgacgg
      841 ggtttgtact aagctcccat gtcctgtaca ttgcaatgta gaagcaggtt tgtcactagc
      901 tgtcagcata ggaaaaccag gatcaagctc gtaaggacca gtaatattct ttgctcggca
      961 aactgtaact gaatgtcctc ttcctgtacc gccttctgcc gtcatcaaat aataataccc
     1021 gttacgaaaa tacaaatgtg gtgcctccgt tttcgctaat tctgtacctg caaatatttt
     1081 atagatggga ccatcaagct tcttcttctc tgcatcatat tcttgtaata cgataccgct
     1141 ggatttattc ggtgtgtcca gacgataatc ccatagttca ttgacaagcc atttttttcc
     1201 cgtttcaaga tcatggaaca aagaaggatc aaagccgtta ctatttaaat aaattggttc
     1261 ggaccaagga cctgtgatct cagatgcagt gatcaaataa ttgtggacat ctttaaacgg
     1321 acggcctgca cttttgacat ctgtgtaaac aagataaaac aatccatcag cataactgat
     1381 ctgtggcgcc catatacttc catttgtagg atttccttgc aaagatactt gagtggtcaa
     1441 aatatccgtt gtatgtgacc agttgactaa atttttcgac tcatatactc ggattcctgg
     1501 aagccattca aaagaggaga caataatgta ataccgctct ttcactctta atatattagg
     1561 atctggattg aatcctctta aaataggatt tttcactttg atagtctgca tgattcaggc
     1621 tccttttctc attcttactc gatataaact gaatgcccca gctgcgaaat aaaaaaatgc
     1681 aaaaggaaac gcaataaact gagtgccaat caacaatatg aatcctgtta taaaatacaa
     1741 accagtggca gttgttaagt attttccttt agcagtcaaa aacaatgcta ctgctaaaaa
     1801 agcaagtgaa ataaacaaca caacggcaaa cagaccagtc atgtcctgta ataatccaaa
     1861 tgtattttct aaagacaaag ttgaatgatc tacagcaagc gactgataac tttttttaaa
     1921 ctctgacgca gacatattac ttaaagtaac tgctaacccg ccaaagaaaa tcaaagatag
     1981 actgccaccg accattccta gcaatagttc ccattttctt ttcatttctg aaccccctgc
     2041 ttttctaaat gtatccattc aggtcttttg atcgatgttt cataattgtt attacgttca
     2101 gagaatttga cagtctgttc atttttcttg tcatcccaat tatcccaacc agttgggtga
     2161 acatgcccac ctatcttaca cgcttcaaat aagacatttg catacggacg ccacggtctt
     2221 cctaaataga cgtttctagt atcaggttct gcagtcaagg tacagctttc aaaacgatac
     2281 cctgtttttt gatttttcgg cgtagatgct gctgtgatgt atccaggatt tttactggct
     2341 aagctatgga tatgacactg atgaaaaacg gcatctgccc caccaaatat gaaatccacc
     2401 gttccttcaa tccagcaata ttcataggtc tgacgacaat actcaggatt ggcagaagcc
     2461 ggtgtacaaa aaggagtacc atctttttgc aaatcaggca acggacccgt gcataaggta
     2521 tcctgataac cagatagtcg acagtttttt aaagatacgc gatctcctga attgaataaa
     2581 gcaacagcct gtcctacctt ttctcctgga cctgctgtat tttcgatgtg aagattttct
     2641 aatacgacat tcgatccttc taagaaaaaa gtagcacttc ggaaagtccc taactggcta
     2701 ccgtcaagat actcctgttt tgcaaaacga ttaccggaga taactactgt tcctgctccc
     2761 acaagtttaa aattggataa tctgctttct atatattcat catatcttcc ttcttttact
     2821 atcaagacct ttggatggct atccggcagg cctgccaaat aatcgattcc ttcttggata
     2881 gtttcaaaat ccgtcggggt atctatagca ttctttccaa ttatcagttt gtctttcatc
     2941 ctcataaatg ctcccttatg aattgtttcc aaatatttct catttcttgt gtttccatat
     3001 gaccgcctgt taaagaaaaa gaagaaaagt tttctggact acccattgat tgatactttt
     3061 tgtccagccc ttttctcagc ttcagtacgc cttcgtccaa gcacatcgta tcgttttttc
     3121 caactaagct aagacgaggg cgcggagcga ttttttcttg gattgctaac gttgtataag
     3181 ctgtcaatag atttggcaca tagtaataaa acccatgatg atctaggcgg cgatgtagca
     3241 aaagtatttc gatgtccacc tgtgccgcta gatcaataca aactttgaca cgagaatcca
     3301 atgctgtcac ccaccagctt aataagcctc ccatagaaag accaatcgtt gcgagccgtt
     3361 gagtatctgt gtcttccctt gtctccaaat aatcgatcaa gctgatcaca tcataaatac
     3421 gcattcccca taacgttttt cctgttaata aaaattgttt gaacaactcg ctttcagaaa
     3481 tacctccgcg ttcttcaaat ccccaagcat caatcgacca aacagcatat cccattcctg
     3541 tcagtacttc tgcaaaagat ggagaagcta agtaaggagc accatggatc aattcacttt
     3601 tcccgactga aaaatctccg ccgtgagaat gcaggtaaag gaccggcgga aacggtcctt
     3661 ctttttctgg ataagcatag agggctggta ctgtttccaa ttcatttaag tacaattgat
     3721 agtattcaag cataaaaccg ttttgttttt ctcggtataa tcgttttcca ctaggggtat
     3781 gtctgctaga tggagcacct aaaaaatcat tcaactgcat aagcaaagtt tttacgaaca
     3841 accagttcat ccatattttc tgattgattt gattggaatt tctcaatact gatttcttta
     3901 gtattttcta atagaaatgc tggtccctcg tgattttcaa tcgacatctg gttaaaggaa
     3961 accttacccg caaagccaat ataaaatcct tgtctgctca tttcctctat tcctgtcatc
     4021 atagcaggaa caccgggaac tgcatcttgg gccatcgaga catcgatatt gtcaaatgtg
     4081 atttcttgta tgaattgttc cgctaatcca taaataaaac ctgcagaagc atggacattc
     4141 cttgccgtga tattcgaaaa atggatcctt ctgaatgctg gtgtccgttc atctatcgga
     4201 taagcctttt tttcccatac atacggttct ttccctcgcg gaccacagaa ataataaaga
     4261 ttcagtataa atggacacat cacattatcc atgactatat tggatactcg aatatcttca
     4321 acgatcccgc ctcgacctcg tctagatttc aatcgtattc ctcgatcagt ttcttggaag
     4381 atacaatttg aaatggtaat attacgaata ctaccactca tttcacttcc taatacgaca
     4441 ccgccatgtc catggaccat cgtgcaattt gtgatcgtga tattttcgca agcgatcctt
     4501 tcgtacgtat cttcagtccc tgccttgatt gcaatacagt catctcccac gtcaatatgg
     4561 caattactaa tacgcacatt tttgcatgat tctggatcaa ttccgtctgt atttggtgaa
     4621 tccgctgggt tcaagatcgt caagttatca aacgttgcat tactgcaaag aatcgggttg
     4681 atcgtccaac ttggtgactg gatcaattta atatctttca cagtaattcg atgacagtta
     4741 tggaaactca tcaatttagg acgaggataa gcgagattat ctggttcatt tctaaaagta
     4801 tgccaccatt tttttccatt tccatctaat gtaccgaaac cagtgacaga gatgttctct
     4861 acattttgag catagataca ggaagcataa acttttcgat ggactccttc ccaacgtgaa
     4921 tgaacaacag gataatcttt tggatcgtca gagaatttca gaaccgctcc tgcgcttaaa
     4981 tgaagttcga cattgctttt taaaaataaa gctcctgtta gaaattcacc tgctggaaca
     5041 actacggtcc cgcctccgtc acttgctgca gcatcaatgg cttgttgtat tgcttcagta
     5101 ttcaattcat caattgatgc gccaaatgtc aaaatatcat acatatttat aatgcctcca
     5161 cttcaatcaa tgcttgcaag aatgcaccaa cgcctttttg atcattacaa ataattggtt
     5221 cactgatgta gtaagcatat gaaccatctc gctgatctgc tccgcctaac cctgctactt
     5281 gacagttttt attcaagttc agccagcctt cttttgtttc cagaacaaat tcatcaagta
     5341 atccttgatg tgatttcttc acttgtggaa gccattcttc tttgttcagc agtcccaaac
     5401 gtattccttt agccattgcg taaacaaaca tactactgcc ggaagcttcc agataatttc
     5461 ctttccgttt tgtttctgtt gttacttgat accatgtccc gctgttttct tcttgatatg
     5521 gaagtaatgc agccagtgtc ttttctagaa tttctttcag caaagaacaa tctgtttctt
     5581 catgaagtaa ttcataggta tctgctgcag ccatcaaata ccagccaatc gatcggctcc
     5641 aaaaatgatg ggatagacct gtttttggat cagcccatgg ttggaccttc ttttcatccc
     5701 atgcatgaat cagcaaattt gtttttggat cgaatagatg tttataactg atttcaaact
     5761 gtctcaaaac atcttggtaa tctttttctt cactaaaatt ctggataaat tcagcataaa
     5821 aaggagaacc catatataag ccatccaacc aaatttgata aggataaatt tctttatgcc
     5881 aaaaagctcc ttcggatgtg cgtggatggt ttgccaactg ctgggaaagg agttctgctg
     5941 cttttttata tttttcttcg cctgtttctt tgtacaataa aaagaaaagc tttcctgtat
     6001 ttacatggtc gatattgtat tcttcaacgc tgtagccacg gatcgttcca tcttcttgca
     6061 cgaaatagtc gatattgtct tttatgaaat caaaataaat tttttcttgg gttcgttccc
     6121 aaagtaattg gaacccttta agtacgacgc catagtcata agaccatttt cctttatacc
     6181 acttttcttc atataagcga ggtgttcttt ccatgatact ttttgctaat ttctttgacc
     6241 agttttccat tatttgctct cctttaaaaa ttaaaatagg atttgggaca aataccaaga
     6301 agtatttgtc ccaatcgtct atattactgt gccgctgctt tgtatgcttc ctcgtactct
     6361 tgtgtgattc gatcgcctcc ttgtgctttc cagtcttcta cagctttttt gaatccatct
     6421 tcgtcaagct gtcccatgat gtattgcacc gtagcatcaa tgacgatttt ttcaatttct
     6481 gatcctactt cattgttcgt cggtgaatcc aatggcacag aaggatccat tacagcaaat
     6541 tcttcatttt ctttgatcaa ttgattagag aattcttttt cagggtctgt atctttgaaa
     6601 gagaacgtca cttcactagg acgagagctt gataacggtt gcacctcttg ttgccaaaga
     6661 tccatatcga taaattcgat agaaccatca tcattcaatt cataatgcgt tccttcgata
     6721 ccgccagtca tcaatttata cacatcttct tctaaaagat catcaacaaa ttgaagtaat
     6781 ttcttcaatt gtgcttcgtc ttttacttga gatttgggaa atgctagcaa gccgccaata
     6841 ccatttcctt ctgaccaaac atgataaccg ccgccttcac catctgagat cttgtttaca
     6901 ggcactaatt ccatatcatc ttgaatacct tgacccatcg tcttcagatt cttgatatcc
     6961 accattccag tgtagattcc agttcttcct tgtgcaaatt gttcttgctg atcagtcttt
     7021 tgggtaactg caaagtcttg tgccaaatag ccattctcaa atagatctct tgaaaaattc
     7081 aaagctttca tatactcttc tgtatcaaat tctggagtga atttgccatt atcgtctaca
     7141 gcccagccat ttggtgctcc aaaataagaa gtgaaaagtt taaagctggt ataacgaata
     7201 tcactaggcg cacgatcgcc aaaaccaact gtgtcgtcca caccatttcc atcaggatcg
     7261 ttttctgtaa attgtttagc tacttcataa agctcatcca tggtagttgg aacatctagt
     7321 cctagattat ccaaccagtc ttttcgaatg actaagccag cacgagcgta gtctttttgt
     7381 atcggtacgc cgtacaaggc accgtcgata ctcgcagctt cgattctatc ttcagaaatt
     7441 tgacttaaat ttttatagtc ttttaaatat tctgatacat cccagaatac gcctgatttt
     7501 aacgcattgc ggacagaaga gtttttcaac atcgcaattt gaagtgtaac gatatctcct
     7561 agttcatcag aagccaatgc agttgttaat ctttcttctt ttgaagcatc aggaatccag
     7621 ttgaatgtca gttccgtatc ggttttttct tcgatcaagt tcacaatcgt gtctgtaggc
     7681 ggtgaagcat gatgcaaaat atttaaccaa gtgattttag cttttccatc ttctgtctct
     7741 gaagaactgt tacttgaact gctgccgcat gcggcaagtg ctagaattcc tgcaaaacta
     7801 agacctaatt ttacgagcgt tgcttttttc ataaattttc tccttcactg ttttaataat
     7861 atttttgttt tcttctgttt tttctgtata tgagttcttc cattccaaat ggcaaaatat
     7921 agaatttgct gtccacgtga ctgcggaaaa gaagagactg ccaccgataa aggttaaaac
     7981 acctggcatt gtttggatga tcatcagata aatccctacc atacttaata tcaacactaa
     8041 tgagtaatga agatgtgaga atccgaataa aaatgccatt ttcattttga aaaaatatcc
     8101 tttccaatca taatgagcca tgattgggaa aatatagagt gctgagagca catatatgaa
     8161 cgcagcaata tacaaagcga tcctaagata ccaattgtgt atgaaagaaa gatccacaag
     8221 taaaacaatc ccgatggcgc catatatcca gctcatcagc aaggtttcac gatagttttc
     8281 tttaaaatat gtgaagtacg ttttcgtcaa aggaaacgtt tcttttgagc gcagccattt
     8341 tctaatcact gcaaccatcg catacgatgc aggaccgaaa gtaaaaactc ccaaacctgc
     8401 gatgactaaa ccgccccaca gaaaattcaa ataaaccaac tgtaaaatac gatttagcct
     8461 tccgtttatt ttatctaatg actgcagcat atctttccct ctctttctat cttagtaaac
     8521 gccgtcttct cctagctttt tggcaatctt attagctaaa attaccataa acaatcctac
     8581 gaccccttta aacaatccca ttgctgtact gaaacttaac tgtccattct tcaatccagc
     8641 tgtataaata taggtgtcga aaatttctgc aacgcttcga ttcaatgaat tcaataacaa
     8701 gtacatatgc tcgaacccta agtctaatgt ctgaccgatt tttagaatca gcaaggtaat
     8761 gattactgga cgaattgccg gcaatgtaac atgccatgtt ttgcgtaagc gtcctgctcc
     8821 atccatttct gcagcttcat acaactgtgt atcgactgca gttatcgctg aaaggtagat
     8881 gatcgtagac cagcccaact ctttccagat cacttgtccg atatatactg tgcgtgtcca
     8941 ttcaggggat gttagaaaac tgattttttc aaatcccatt gttgcaagga attcattcaa
     9001 tacccctccg tcaacattca aaaatacata agtaatcgaa acaatgatta cccaagacat
     9061 gaagtgaggg atgtaaatga tcgtttgaat cccgtttttc aatcgtttgt tcgttacttc
     9121 atttaatagt aaagacaaaa tgattggcat cggaaaaaac acgaagatat ttaatccgaa
     9181 caagatcaac gtatttctta ataatgtaaa gaatgtcggt tctgtaaaca aacgaatgaa
     9241 atgtttgaaa ccgacccaag gacttcccat tattcctaaa aatggttgat aatcttgaaa
     9301 agcaataacg agtcccccca taggaagata cctaaaaatc aagaaataaa ggactcccgg
     9361 cagaatcatc acatataaaa atttattcgt tttgattcct gcaattattt tttttcgtct
     9421 tctgagcttt tcttcttttt tcgatagcgt cagttgaaat ggttcttgtt tctttacact
     9481 ttccataagc ccctccttag ttttgtgaat gtttgctgct tatgacttca tgatagataa
     9541 ctatctgaat tacgtatata atcattttta ccgtaagtaa aaacgcttac atagcaatga
     9601 tttttgtgct atacaaaacg ataaagtgta ttttttcaca aataaactac gcatagcaaa
     9661 ccttctattt ttttctatct gacacttagc ataggaaatg attatatacg taatctttca
     9721 ccgatgataa attgaacata tagaaacaga aacatttaat ttattttgag gaggagccta
     9781 tctatatgaa aaagaaagtc tctataggag aaagaagttt tacacttttc aacaatacgt
     9841 ttctaatttt gctagctttg atctgtatcg ttcctttttt aaatatcatc gctacatctt
     9901 ttgcttctac acaagaagtc gtcgcgaaaa agtttatcct ttttcctact accttttctt
     9961 tagacgcgta tcgctacatt ctttctacgc cgaccatttt tagagcactt gctgtttcga
    10021 ttggtgttac aggtgtcgga acgatcgtca gtatgtgtgc aacttcactg atggcctacg
    10081 gtctttccag aaagtatttg tttggtcgag gtttcgtcaa ctttcttgtt gtattttcta
    10141 tgttgttcag cggggggatg attccaacgt tcttagttgt tcgttctcta gggctggtca
    10201 attcttactg ggccatgatc ctgcctgtgg ctgttaatgc aatgaatatg atcattatga
    10261 gaaacttttt ccaagccttg ccggatagtt tggaagaatc agcaaaaatg gatggttgca
    10321 cagattttgg tgtatttttc aaaattatgc tgccattagc gttaccgtct attgctacta
    10381 tctcgctttt ttatgctgtt acttactgga acacttatat gactgctatt ttgtatatca
    10441 acgattcatc taaatggccg atacagattc ttttacgcca aatcgtcatt gtatcaagtg
    10501 ggatgcaagc agaaagtagt gccgttgatg tgattccacc agcacaaaca gttaaaatgg
    10561 ctgttatcgt tattgcaaca gtgcctatgc tgattgttta tccttttgtt cagaaatatt
    10621 ttgtcaaagg agcactcgta ggttctgtca aagggtgatt atgtactgaa cgcaaaatgg
    10681 tagttgtgtc agaagtggtc agcttcaaga aataagaagg catttacgaa aattgcttct
    10741 taaatttttg tgaaatttcg gcttattttt cgaagaatct actcctggaa caccgtgtat
    10801 cagaggttgt gaaagagacg ttcagccttg agcgatgata aaaactctca caaacattgc
    10861 gacgagtaac ccacaggagc aataagaagc gattttgaaa aatagcttcc catatttcac
    10921 aaaattatgc cttattgtcg atagcctgtc tcttgaacgc catttattcg taaaaaagaa
    10981 ctgtgacaag acttttgtca cagttctttt tgcgtgctta gccttgaaat ttaactatcc
    11041 ataaatacaa atactagggt tattctaact tcttttattg cttgaatcag tccacaagaa
    11101 aaacagcctc ttgattcaca aatatttttt tcgatattct cccggcgtaa tcgattcctt
    11161 ctttttaaag aaacgaataa aattttgcgg atttcgatat tgcaatcttt ctgcaatctc
    11221 ttttacggag aggttagtct ctttcaacca tttttttgct acctctaaac gatgattttg
    11281 aacaaaatca ccaaattttt ctcctgtttc ctttttaaat acattactta aatagttagg
    11341 gttataatgc aacctatcag cgatcacatc taaagacaga tcacgatcat attctgtgta
    11401 gacgatatgc ataatattct ccgacaaatt tttaaattca tgatcagtga ttgcttgaga
    11461 gcattctgtg attggcagaa ctaattgttc taaaacaagt ttttctagtt ctttgggatg
    11521 ataattgttc agtgctttta cataaatttg tttcatgtta tcaaagtttt ttgaatctac
    11581 tcccaataac tgtcctaatt gaacgagttc attgatcaag cggaccgaaa ctacttcccg
    11641 actcaaagga tttttatttt gtgcaaacaa tgcatcaatc aattcatgta ctaaattctt
    11701 cacttcctga tttccagaac gaatggcttc aaacaatcga ttttgttctt ctatcggata
    11761 tctaataagt gttttttcat gagcagcagg aacgatttcc tgataaaaaa taattgaact
    11821 tggaccagta tttacacgat aatacagggc ttcttttgcc cgatcaaccg attgcttgct
    11881 ttcattcagc gtttcgaacc ggttactgat gcctatactg atagttaaat tcaagtattc
    11941 ttttacacgt ttttgaatga gtcggcaata ctccatgact tttttgcttg cttctgcatc
    12001 atctttatcc attcgataaa tagtggcttg catttcttca ttcaaaacga tcggcagcat
    12061 tcgattttcc tttggcacaa tttccgtgat catgttgttg atcgctaaaa gtagcaaatc
    12121 acgctcccca ccgtgactat cttctaacag atcgatttga accaaagctg tataatagca
    12181 gtcattttga gaactataac caaattgctg caaccgctga tctagttctc gcctttctac
    12241 tcgatttcta aataaactaa gtacaaatag cgtttccagc tgtggctttt gggtaactaa
    12301 gtgtgcactt aacgcttctt tttctcctat gatccgactg actgattgag cgaccaaatc
    12361 tagttctttc ccactgaatc cttttgattt aagattcaga cgttcctgta tttgagaaat
    12421 cggacgggca aatctgtccg aaaataagta ggaaagaaga ccaatgagtc ctaccagtgt
    12481 taaagacact gcaactagcc cgattctcag attgcggatc attgcgccaa ttgcactaga
    12541 gtcaacttct aatctgtaaa tccaattatt ataatctgat ttcagtacta tatacgtttt
    12601 atctttttct cttatcactt tcagctgatt gtaatctaga tccacgtccg ttaatacagt
    12661 tggttgctct ttatttttta ctgtctgagt agtaaaaagg ttgccaactt cgttttcaat
    12721 agaaagtatg tcttctccac tttcaccaac aacttgttct attgtatgtt tctctatcgt
    12781 agcaattccc aatgcatatt tttctttttc aaacattggc aaagaaatca ccatttcgat
    12841 tcctttgttt ttcttttgcc aaaataaatt atttttgtta tttatgtact tctgttgata
    12901 cttttcaatt tcctcttcgg tcagttgact caacgatcca ttgattactc cccatttacc
    12961 agccaaactg actaaatcat aattattatc atccataaca atcgtttcta taaaatttag
    13021 ttctttcctg atttcagaat aagtggagta atctgtatat gtcagcggat gcttgaatat
    13081 gtccgagaaa tttttggtcg aaccatacgt agaaaacgaa tattcaatcg ttctaatttt
    13141 ccattcaacg ttagttttaa cttgcctgag caaattcttt ttgtctgtta aataactcga
    13201 ttcgatcgat tcataggtat tctggtaaat gaataaacta aatcctatga caagtacggc
    13261 tcctaataaa aacatcggta aaaatatttt ataaaatact gtacttttct tcattttctt
    13321 cctctcctcc ttttaaaata aaaggctttc atttttctgt aaaattgata ctcatctaat
    13381 taaatgagca ttccccgctt tcaagaatag cataattaaa aataaaaatc caagtaattt
    13441 ttaacgtgtg caatcttttc atatcaaaga tctattgact tatcgtagtt atcgtaatat
    13501 gatgaatgcg ttaacaaaaa gtgaaaaagt aaggaaaatg atggaatggt aacgatcaaa
    13561 gatgtcgcta aagcagctgg cgtttctcat acgacagttt ctcgtgcttt gaataacagc
    13621 agtttaataa aaaatgaaac aaaacaaaaa atacgacaac tagctaagga aatgaattat
    13681 tcgccaaact atagtgcaaa aggtttagtg aatcaaaaaa aatatctaat cggactattt
    13741 ttctcaagtt tgcataaagg aacttcatca aatttcctag cagattccat tgcaggcatc
    13801 cattcagtat tagacacaaa ttacagttta tctgttgaaa gtatcgatgt tgttgattta
    13861 acagaaatca acctgcaacg ctacgatgga ctgatcgtta tgagtcaaag tgatgatgat
    13921 cagcctttca tcgactatct caaagaaaaa gaatttcctt tcgttgttgt caatcgtcac
    13981 atcaatgatc cagcggttat caacgtcact gccgatgatg cggccggtgt tatgcaggca
    14041 gtagattacg gtattggatg cggacatacg aagatcgctt atattggcgg aaagaaaaat
    14101 tttcgttcga caaaagaacg ggaaaaaggg gtattgaaaa gtctaaaaaa agcgagcatc
    14161 cctgtcaatc cagcctattt tttaacagga gattacagct tagaaagcgg cctccaaaac
    14221 atggaatacc tattatcact ttctgacctg cctactctgg ttttttgcgg caacgacgac
    14281 atagcgattg gtgcattgag agctgtacat ttagctggcc tccgtgttcc ccagaacatt
    14341 tctctgatcg ggttcgatga ttctccagtc gtctcctatc tcaatccgcc gcttaccacc
    14401 gtacgtaagc ctttgaaaga aatgtgtcaa gaaggaacaa agcttttact agatttgatc
    14461 gaaggcagga cgatcgaaca atctaaaatt gagctctcca ccttgttgat ccttcgtgag
    14521 tcgatcaatt acttgtaaac tacaagtaat tttatataaa aatgttaacg tgtgcataac
    14581 acagaaagga agtttatatg aaaaaactga caaaagaatt agtgaaaaaa aacgaagcac
    14641 ctgtaaaagt tcttcagttt ggtgaaggca attttatgcg tggatttatt gattggcaga
    14701 ttcagcagct gaataaccaa caattgttta aaggtaatgt tgcaatcatt caacctttag
    14761 aacaaggtct tggaaatatg atgaaccagc aagataattt atatacggtc attttacaag
    14821 gactcagcaa tggcgaaatc gttgatactt ccgagattat caccgtagta gaacaaatga
    14881 tcaatcctta tgatgaatgg gatgcttatc tatctctagc agaaaatgac gacttggcct
    14941 atatcgtctc caatacaaca gaggcaggaa tccaattcgt ggagactgat aatttaacag
    15001 atactccccc acagagcctc ccgggcaaac tgacagcctt tttataccga cgtttcaaat
    15061 taaacaaagc tggctttacc atcattcctt gcgaactgat tgacagaaac ggcgaacgtc
    15121 taaaagaaat cattttacgc tacgcagaaa aatgggattt agaacctgct tttgttgagt
    15181 ggttagaaaa agaaaatgtt ttctgttgta gtttagttga tcgcatcgtc ccaggttatc
    15241 ctcgcgaaga tgcaggtgtt ttcaatcaac ggcataacta tgaagatcaa ttgatggtca
    15301 aagcagaacc attcatgctt tgggtgatcg aagggcctaa agaattggag aatcaactac
    15361 cattcaaaca ggctggcttg aatgtcatca tcacagatga tatgactcct tatcgtgaac
    15421 gtaaggtgca tttgcttaat ggaccgcata cagcgatggt ccctcttgct ttgttggcgg
    15481 aattggaaac tgtagaagaa gtaatgaaag atcctttatt ctccgcatat gttgatcagt
    15541 tattcaatct agaattgatt cctatgcttt ctttacctaa agatgaatta gccatttatg
    15601 ctgaccaaat caaagaacgt ttcttgaatc cttttgccca tcacaaatta gaagcgattt
    15661 cattaaatag tgtttcaaag ttcagcaccc gtctgcttcc agtgttcaag aagtatatcg
    15721 aagaacaaaa tcaggtacca ccgttaatca ctgtttcact agctgcgcta cttcttatgt
    15781 atcgaggcga tcaagtaaag ccacatgatg atgaaaagac gataagcgaa tttactgatg
    15841 cttggtctga taatggaaca gctattcctc gattattgca aaacgctgcg ctttggggag
    15901 aagatttgtc tcaaataccg aatgtgacag atacagttca agaaatagct gcaaagatcg
    15961 atcaaaaagg tgtccggtca gtattacaag aaatgaaagg aacgatggtc catgcttgaa
    16021 accctgcaac caacaatgaa attaaatcga cgagacagtg tggtcgtcgc attaacccct
    16081 attccaaaac aaacacaact gacgattgat cagcaaacga tcaccactct tgaagatatc
    16141 ccgcaaggtc ataagattgc attgggtgat ttgaaagctg gagacaacgt gatcaaatat
    16201 ggctatccaa tcggtcatgt gacgacagac gtaactgccg gtcaatggct gcacactcat
    16261 aatgtaaaaa ccaatctttc tggtgaattg gattatcgat atgaaaaaga tgtccatcca
    16321 agtcattacc tttttgagaa ccgaacattt caaggttact tgcgaaaaaa tggaaaagta
    16381 gggattcgta atgatttgtt tttagtacct accgttgggt gtgtgaatgg cattgctgaa
    16441 ctgatcgtca aacagttcaa ggaaaaacat ccagatctgg gacagtttga ccatattacg
    16501 attttaaagc atccttatgg ctgttcgcag cttggaaaag atcatcaaaa tactcgagaa
    16561 attttagcgg acgcagtaaa tcatcccaat gccggaggag ttttagtatt tggattaggt
    16621 tgtgagaaca atacagttcc tgaattcaaa aaaattttag gtgaatatga tgaagaacga
    16681 gtgaaatttc tagtggctca agatgtttac gatgagatcg aacaaggtgt ggctctatta
    16741 gaagagcttt taacagcggc ggaaaatgac cagcgcatat cagtcccgct ctctaagttg
    16801 aatgtcggtt tgaaatgcgg cggttctgat ggtctatcgg gaataactgc taatccttta
    16861 cttggtgcat tttctgacta cttgattgct caaggaggca gcacgatctt aacagaagtg
    16921 ccagaaatgt ttggcgcaga acaagtattg atggcacgag cggaaaatga agaagttttt
    16981 gactcaatcg ttgacttgat caatgacttc aaacagtatt tcttgtctta cggggaacca
    17041 gtttacgaaa acccatctcc tggtaataaa gcaggtggga tcactacatt agaagataag
    17101 tctttaggct gcacgcaaaa atcaggaagc tctcctgtcg ttgatgtgct acaatatggc
    17161 gaaaaaatca gaaaaccagg gcttagttta ttgcaagctc ccgggaatga tcttgtagct
    17221 gcctctgctc ttgcttcatc cgattgccag ttggtcttgt ttaccacagg aagagggact
    17281 ccgtttggct catatgtccc aacggtcaag gtatctacga atacaactct ttttgaacgc
    17341 aaaggtcatt ggatggattt taatgcaggc gtcttattag aacaaccaat ggaagtaatc
    17401 ttagaatcgt ttgttcaaaa aatcatcgct gtagctagtg gagaagaaac gaaaaatgaa
    17461 caaaatgacg ttcgagaaat tgccattttt aaaaacggag taacactttg attttcataa
    17521 aacagtataa aaagaaagaa ggaagattta tgtttttatc tgatgatttt ttattaaaag
    17581 acgattgggc gaaaaagctt taccattcct acgcaaaaaa catgcccatt attgattatc
    17641 actgtcactt agatccaaaa gaaatttacg aaaacaacaa tttcagcaat ctgacagaag
    17701 cttggttagg aggcgatcat tacaaatggc gcttgatgcg agcttgcggc gtgcctgaag
    17761 aaaaaatcac aggaaatgct tctgattttg aaaaattttt agcttggtgt caaaccgtac
    17821 caaaaattat cggaaatccg ctttacagtt ggtcacatct tgaattgaag cgtttcttcg
    17881 gtattgactt gttgataaat gaagaaaatg cagagaaaat ttggacacaa gcaaatgaaa
    17941 ttttggcagc tcctgatttt cgccgtcggg aaatcgcaaa aaaatcgaat gtagaagtga
    18001 tttgtacaac agatgatccc gcagacgact tgcactatca tcagttgctt gctcatgaag
    18061 aaccagattt gaaggttcta ccttcattcc gtccagataa agcactcaat attgaaaaag
    18121 aaggatttaa tgcatgggtc acactactgg aagaagcagc tgaccaaacg atcaccacct
    18181 atcaagaact gatagaagtc ttagggcagc ggatagaata cttccatcaa catggatgtc
    18241 gtgtttccga ccacgcttta gacatcttac gctataaaga agcggatgaa acagtattag
    18301 aagagatttt tcaaaaagca cgagctaaca aactattatc ttcagatgaa atcgatgctt
    18361 atcgtacaga aacactgata catttgaccc acttctatca ttctcataat tggacgatgc
    18421 agctgcacat ccatgcttat cgtaactgta atacacaaat gttggaaaaa ttagggcccg
    18481 ataccggcta tgatggaatg aatgatcttt ctttgactat tcctctgcaa aaattattga
    18541 accgtgcaga agaaacggat cagttgccaa agacgatcct ttattcattg aatccgaatg
    18601 actatcctgc gattttagct ttgatgggct gtttccaaaa agaacagaat ggaaaactgc
    18661 agttaggttc tggatggtgg tacaacgata ctcgagctgg tatgcgcgat caattgacac
    18721 aatttgctga tggtagtgct ttggggaatt ttgtcggcat gctgacagat tcaagaagtt
    18781 tcctgtccta cactagacat gaatatttcc gtcgtgttct ttgtgaattt ttaggcgaaa
    18841 tggtcatgcg aggagaagca cctgaagatg aacaactttt aggaagtcta gttcaagcga
    18901 ttagttatac aaatgctaaa aattactttg gcttttttgc ctaattgatt aatagtaaca
    18961 gtaacgaatc aaaaacagga tagtgaaata acggaatccg tttatccacg ttttagagaa
    19021 gaagacggac caaatttgct ccgtcttctt ctcttgctgt tctgcttcat tgcctataaa
    19081 cctttatgaa agaagagata acatgcctac tatccatatt gccggtgatt ctactgcggc
    19141 agaaaaagat gaaaacaagc gtcccgagac aggttgggga gaaaaaatct ctgcttattt
    19201 ttcacccgag atccagatca ataaccaagc aaagaatgga cgcagcacca aatcatttat
    19261 ccaggaagga aggttagccc gtctagcttc acagtttcag ccgaatgatt tcttatttgt
    19321 acaatttgga cataacgacc agaaaatcca agaagaaaga ggtacgcttc ccttcggtag
    19381 ctatttaaaa aatctgcaga tattttttga atgcgcaaaa aaagcgaacg tccaaatggt
    19441 cttactgaca tctgtgacgc gacgagatta cttagaaaac ggaacattga atccagatat
    19501 acttggagac tatccaaaag cgatgcgtgc atttgctgag aaacaccata ttcctctttt
    19561 agatgtgttc tcaagatcac aagaattgtt ccagaccttc tcaaaagaag agacaaaaaa
    19621 attctacctg catcttatac ctgatacttg taaaaattac ccagaaggac taaaagacaa
    19681 tacccacttt agtccagaag gcgctgataa agttgcccga ataattgttg aattgataaa
    19741 agaatcccgt ctgcctcttg ctaattattt acaaaaagga gtttgagatg tttccattaa
    19801 atttaggcat ccgtgcccac gatttagatg ttcgaaatcg tgaagaaatc gttcaaaaag
    19861 tatcacagct tcacttgtcc catatccaat ttgcaccaca aaaagcattt cctgaacaac
    19921 ttaaattaac tgacatgaca cttgggagtg ctgcctattt tggtgaatac ttccaaaaaa
    19981 acaatatcga actttccatt ttaggatgct atatcaacct atccagcaaa aatcaagaag
    20041 ttcgtgcaca agcattggca actttcaaac agcaaattgc tctgtgctct gcctatcaag
    20101 ccaagatgat tgctacggaa accggtagtg tctctgtcgg ttacacaaaa gaaaatttta
    20161 ctgaagaagc ttatcagatc gccagaaatt ctatcattga attagtcgct catgcagaaa
    20221 attttggcgt aactgttgct gttgaagcag ggatcaatca tccaatctat aactatcagt
    20281 tagctaaacg tttaatcgat gaagtagctt caccaaattt aaaaatcatt ttagattgtg
    20341 cgaatttgat gcataaagaa aatcatgctg atcaggaaaa agtgatccga ggtgccttgg
    20401 acaatttaca tggttatatt acagcgcttc atctcaaaga ctatatcatg gaaaatggaa
    20461 agatccgcat ggtacctgtt ggcaagggct gtttagattt ccgcccggta ctgcattata
    20521 tcaaatatga gcgtcctcta atgtacgcca ctcttgaagc tactcctgag atttatgttc
    20581 ctgaagcaat agaacacttg cagtttattt accaagattg ttaaggagaa gattatggag
    20641 gaacgaatac agaaaagtta tcaaaaatat catgcaaatg cttttcagac attgctgcat
    20701 ctttatcagg gaaattattg gcgttttgcc atgtcaggac tcttttttat tatcaaacat
    20761 cttccatctt ggttaatgcc gatcgctatt gccaatgtaa tcaatgcagc ttcatcgaaa
    20821 gattcttctc agttgcaggc catttatttc aacgcttttt tgatggcttg tctgattggt
    20881 caaaatatat tgacgaatta ttttcatgta aaataccata gcacttcgat ccgtcaagta
    20941 gaagctggac taagagcgac ccttatcaag aaaatccaag aactatctat tccttatcaa
    21001 aaagaattgc aatctggacg aatccagtca aagatcatcc gtgatgtaga agctatccaa
    21061 acgttgtcct ctcaagtatt tgtcagcgga ttaaatatcg ctgtcaattt attcgtagct
    21121 ttaggtatca cgctttataa aagtcctgtt gttttcatgt ttttcttatt gactgttcct
    21181 ctcgccgcat tcgttactct ctttttccgt aaaaggatca gacagtccaa ctcagacttc
    21241 aggcaagaaa tggaagagac ttctgcaaaa gtgatcgaag tgatcgaatt agcaccgatt
    21301 gctcgagctc atgggttaga aaaacacgaa acaactcgct taaataagca ttttactcaa
    21361 atctatgaaa aaggattcca cttagatatc ctgcaatctg ttttcggatc agtcagctgg
    21421 gctagttttc agatatttca gctgatttgt ttgattttca ctgggatatt agctttacaa
    21481 gggcgcatcc aacccggcga tgtcgtgatg tatcagacgt atttcacgac gatcgtcaat
    21541 tccgtttctg gaatgatcac gctgattcct acgatttcaa aaggcatgga atctatcact
    21601 tctattggcg aactgttgat tgctggcgat gtagaaactt atcacggtaa gaaaaaaatc
    21661 caacatttgg atggaaattt tcgttttgag gatgtttctt ttctttatcc ggactcactc
    21721 aaaccgatta tcgatcattt ttctctagag gtgaaagctg gagaaacaat tgcttttgtt
    21781 gggccatctg gctctggaaa atctacactc cttaacttat tgattggatt tatccagccg
    21841 acttcaggaa aaatttttct agatgatcag cctttggatg aactggatat gcgaagtgtg
    21901 cgaaattatt tagccgttgt tcctcaaacc actttgttgt tctccgcttc gatcaaagag
    21961 aacatcactt atggcttgaa aaacgtatca aaagaacgtt tagatgaagt catcgaagct
    22021 gcgcaacttt cttcactgat tgaccagctt cctgatggtc tggatacctt agtaggcgaa
    22081 catggcaaca agctgtctgg tggccaaaag caacgtatct ccattgcacg agcgttgata
    22141 cgtcagccaa aaatcatttt gctagatgaa gcaacctcag ctttagataa ccagtcagag
    22201 aaaaaaatcc agcaagccct gaattacctg acagaaacac ccactacttt tattgtggct
    22261 catcggcttt caacgatcaa agaggcagat aaaatcgttg tgatcgatga aggaaaaatc
    22321 gttgaaatag gtacttacga aaaactgtta gctcaaaaag gctatttcta ccgcttgaaa
    22381 aatgaatgac aaaaaatagg agctatgaca agacttttgt cgtagctcct atttctgaat
    22441 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atagtcatca aacatgagaa
    22501 gctgtttttt gaaattgttc cttgtaactc agagttaaac ggtaggctca cgacctcttg
    22561 gtaaatggtg ttcaagagac agcctatcgg caataagaag caattttgtc atcgctcaag
    22621 gccgaacgtc tctttcacac cctctgttgt ttcataaaat agttttattc gctgtaaagg
    22681 tcgcgaactg gtgtcatgat gatacggttc aagtcattga tgattgtact gaagccttgc
    22741 tctttttgca tcaagtcatt gattacttct tctgattgga ttttcacagc catttcttgt
    22801 gctttcattg catcttcgtc gctgaactct tgtccactca tttgtttttc ttgtaattcg
    22861 atttgcatcg cttggaagtc tttgaacagt ttgtgtgctt cttcgtttgc ttgtactttc
    22921 tcgtacgctt ctttcaacgc tttgaattct ggtaattcac ggatctcacg ttcgatttga
    22981 ttcgcgctat cgtagatgtt tgacatgtta tgccctcttt tcttttagta gttactctct
    23041 attgtaacat ggggttattc gttttcaaag gggctactct ccttgatatt tccgccagag
    23101 gtctttagcc gcttcaccaa ttccctgaac gccttctttc accatatcgc cgaagttttt
    23161 cagcccttct tttgcttgtt caccatattg attcaagtta tcttgccaat ttccagactc
    23221 tccattagaa tttcctgtgt ttccaacttg atctgcagct accacttgtc ctcctgtggc
    23281 ataggcatct gctacactaa atcctgtttt tgaagtatac ggaaggatgc cttctgccgc
    23341 tgatttgaag actttcccga caacatttcc acttgtccct tccaaatagt gcagcttgct
    23401 ggattcttcg taacccatcc atgtcgaaat cactacgtct ggcgtgtaac cgatcatcca
    23461 ttggtcattt gcttttgtgg catcgaaatt agtttctgtg gttcctgttt tccctgctat
    23521 cgtataacct gcaggattcg cagcagccgc tgttccattt gaaaatgtac caagaagcat
    23581 gctggtcatt tcatcggctg tttcctttga tatgacctgt tttggttttt tgtttgtgtt
    23641 atcgacgatc accgctccag tcgaatcaac gattttcgtg ataagatgcg gcgtatacat
    23701 ctgaccatca ttggcaaatg cactgtaagc acccgccatg atcaatggag atactccttt
    23761 ttccagtcca ccaagggcta agccataata cttatcagat tttgctaaag gcaggccgaa
    23821 ttcttctgct ttatcatatc ctttttgtaa accgatctca tgcaaaagcc atacagtagg
    23881 caaattcaaa ctttgtgcaa cagcttgata catcggtact tctccttggt atgtcccgtc
    23941 aaaattatgc gcatcgtaat aactttgcgg ttcgtctttc aagatactgg aaggcttgta
    24001 tccagcttcc agtgctggtg tatatacgct taatggtttg atcgttgatc ctggtgaacg
    24061 acgcatctgt gtagcaaagc tgaatcctct aaagacatga tctcctcttc gtcctactag
    24121 tgcttgtaca ccacctgtat tcggatctaa agctactgaa gcagattgga ccatggcacc
    24181 atctgaagca tttgctggga ataatgcact gttttgataa gtagcttcta attgcttttg
    24241 ataatcctga tctaaagctg tatagatttt atagccttta ttcatgacat cttcttcatc
    24301 aagaccatac tcgttaactg cttcatcgat cactgcatca aaataataag gataacgata
    24361 accagaatct gaattatcgt atgtgtcatt aagatacgcg ctgatatctg tctggctttc
    24421 tgcttgttct tgttcttttg tgatttttcc gttttcttcc attacactta gtactgtgtt
    24481 tttccgatca ttcgcatttt ttgggtgatc gatcggatta taaataccag gacctttcag
    24541 cattcctgcc aaagtagcag cctcagacag cgtaacattc gttgcatcta ctccaaaata
    24601 ctttctggaa gcgtcttgga caccccatac cccgttgcca aaataggcat tgttaagata
    24661 catggtcaag atttcttctt tgctgtactt cttttcgatc tcgattgcca aaaataattc
    24721 cttcgctttt cgatcaaacg tttggtctaa tgtcagatac gcatttttgg caagctgctg
    24781 agtgatcgta cttcctccgc cccctgatgt tccgccagac aagaccattc ggactgctgc
    24841 acgggcaatc cctttgatat caaacccgtg atgctcgtaa aaattcctat cttctgtcga
    24901 gattactgca tcttggatat agggagaaat cgcgtttaat tctacatatg ttcctttttg
    24961 ggcgtacagt gtgccagctt cttcgttttt cttatcataa atgactgtcg attggcttaa
    25021 tcctgatttt aacgtttcga catttgcttg ttttgctaaa ataaagaggt agatacttgt
    25081 cactaagaca cagatcaaac caatcagcaa aatcaatttg ttcacatgat attttttcca
    25141 gatgcgcttt cgccatcgat ggaattgtcc gagatatggt ctgatccaac gccaaaaact
    25201 gatcaaagca gcttttatct tttctaaaat gctttgaaaa tccatttgct tcttctcctg
    25261 tctatttgat tcaatcgtct tattttacca tagtgaaaga gtgttttctt cctgcttaag
    25321 ttgtagttca atatgttttt ttacgttagt gcaagtagag taacataaga atgaacagaa
    25381 aaatgtaagt tttttcttaa atatgtttta aaaatggtac aattagtctg cgattgcact
    25441 gaaaggagta cacttgtgaa aatcacgatc actttaccta tgaaccatcc tgaaacaaca
    25501 attcgcgact tgcttgaaaa ggaatggtta gttcctagaa aggttcgaca ctttttgcgt
    25561 atacgtaaaa acgtttggat caatcaacaa cctgctttgt tccatcatga agtaaagggc
    25621 aatgaccaga tcacattgtt attcgaagaa acagattata attatcaaga agttcaatta
    25681 ggagatgcga agcacatccg tgttttatat gaagatgagc atttgattat agtggataag
    25741 cctgcaggaa tgaagactca tccaaatgaa ccgacagaaa acagtacctt actcaatcat
    25801 ttagctgctt atctcgacac taaacagcaa cgaccttacg ttgtccaccg cttggacaaa
    25861 gaaacaagcg gtgccgtttt atttgcaaaa aatccatttg tcttgccgat acttggaaga
    25921 atgttggaac aaaaaatgat ctatcggaga tatcaagcca tcgtatgggg agaaattgcc
    25981 aaagatatga ccatcaccaa taaaattgga cgagatcgcc atgatcggag aaaaagggtc
    26041 gtagatgata aaaatggtca gagcgccttg acacatgtca ctgtcaacaa agtactttct
    26101 gaacaaacac aagtctattg tgttttggaa accggacgta cacaccagat cagagttcat
    26161 ttagctcata agggacatcc gatcgttgga gaccctctct accaaaatag aacagctgaa
    26221 cgactgatgc tccatgcatt agaactgcac atgatccatc catttactca agaaaaaata
    26281 gtcggtaaag ctttacctgg attatgggaa tagaaataaa aaagaacaga gtcttatcag
    26341 cagataatga taagactctg ttctttttgt gtaatttgtc tgcttacttt tgatgttcgt
    26401 gttctgctaa cagcaaacta ccgataatcc cactttcatt cggcagtccc caacgaacga
    26461 tatattcact tacttgaggt gtttccatat aaccacccat caattcaaca aattgctgac
    26521 ggattttttg aaggagatga tcctgattca ttaccccacc gcctaaaata atcttttcag
    26581 gtgctaacgt caacgtatag ttgatcagtg cttgagcaat ataataagcc tgaatagccc
    26641 aaacaggatg atcttgcggc agatcttgcc ctttgatccc tgtgcgtgcc tcaatagacg
    26701 gtcctgctgc taatccttct aaacaatctt tatgataagg acaagtacct tcataatggt
    26761 catctggatg gcgtttcacc caaatatgtc ccatttcagg atgtgcgatc cctgaaaaaa
    26821 tttcttcatt gatcacgaca cctgcaccga ttcctgttcc cacggtaagg taaatacaac
    26881 tattttttcc ttgtgctgct ccttgcttca attccccata tgcagcagca ttgacatccg
    26941 ttgtccaagc agcaggaata ttgtagcgtt ccttgattgt gccaagaaaa tcgaattgtg
    27001 cccacccttt tttgggagtt gccaaaacgt atccgtaatt atcttttgtt ttgtcgatac
    27061 caatcgggcc gaatgagcca atcccgattc ccttcaattc ataacgatca aaaaattcaa
    27121 atacctgatc caatgtttct tctggtgttg tggtagggat acttaatttt tctaaaattt
    27181 ctccaccatc tgaaaccgca cacacaaatt ttgttccgcc tgcttctatt ccgccataca
    27241 ttcgttttcc tcctcgaatc cgattgtccg aatctcataa ggttggatta ttgggacaac
    27301 cgcttgcttc gttggttctt caagcagatt caatatgaca gtttttccat tgtctttagt
    27361 tatttccaat ttttctaaat gactagacat attgaaacct cttactacta ctttatcact
    27421 aaacttgctg cgtttcaaag ctgtaattgc aaacgtttca ctttttatcg ttaaatattg
    27481 ttgttttgaa atcaatgttc cttcatgatg tttgatttgt tgagtggaaa aaggaatctg
    27541 tgctgcgtat gcatgcaaat aagtagagaa tttttcttct ggtccatgta gttcaatgct
    27601 gtaattgaac cgatgctcac ctagacactg tgcttctggt gttggaaaat atccccaatc
    27661 gcctagttct cccacactgc gaagtagcgt cactgcgatt tgtccgtctt ctgttacttc
    27721 atattcattc aaaccaaagt ttccgactgt tacaccgtac tcttcatcat gaatattgac
    27781 aaatgcttgc tgatgttgcg gattcgtggg gttttcccaa cttttagaca catggtttgg
    27841 gcgcttcacc acttcaaaaa tactatctgc ttcgtgatgt tccacatgta actttgtagg
    27901 aaacaagaca cgtaagcgat gatctttcat ctgattgtcg agagtcgttt caaagtcgat
    27961 ttttttacta tcttttctga ttgtcatgat tgtttttatt tgaaggattc gtttttcttt
    28021 ggatcgttct gcttttcgat aacgaaattc cacaaccatc tgctgttctt tttctaaacg
    28081 ctcgtctgca gaaacaggga tttccatttc ctgtagaata cttatttttg ctatttccgg
    28141 tgtatctact aatactttta cttcagagtt ttctttgtta ctggatagga ttggctgatc
    28201 acagaaaggt tgtttaaaga tatactcatt tcctatatcg ccgatatctt caaaaatatg
    28261 cagattattc aactttcgtt tgtttttgcg atcttccatt gtaatggtac catttttttc
    28321 aatcgtcaaa tgtagagggc cgttttcgat gattcgtcca ctctgatgaa tcattgtttc
    28381 cttttcttct gctttcgctt ccccttctac aagcgcgaat gtttcccaag aaaatgctgg
    28441 catgttttct aatggtaaag tcactttgat cattcttgcc atatatggca cacggaaacg
    28501 gtctttcggc aaatcataac caaattggac agtttcttca gataaaatag ctggtatagt
    28561 ggccccactt tttgtttcta catgatactt acgtttaggc aaattttcta actcttgata
    28621 tagttgttca ggtattcctt cagcgaatct ttttctttct aattcgatgg ttatttctgc
    28681 ttcaccagtt ttatccattc ctgcagtatt tacaatgaca aatggaaagc tgtcttttgg
    28741 gaatccggtc gtatcgattg ctgcggtcag ctgttctaag gaatcttgtg caagatactt
    28801 tccaacttca tctgcttttt caaaacgagg tatcatttcc cgatggacag aatcgactga
    28861 acaaccgcaa atactgtcgt gaggatgatt ttgcattaat gtcttccaag cataatctaa
    28921 ttgatcatgg ggatagtttc cactaacttc ataagccatc gtcgcaagtg gttctgtaat
    28981 attttctagc tgtcgctgga ccttggtatt ccattgtttt aagtaaaccc gagcagatgc
    29041 tgtattggct aaagtatacc agccatccgt ttcttgactt gtcaattctc cttctactga
    29101 gcctaagtct tctggcacat ctttttgaac tgcttccaga tagtcagtaa aattagaatg
    29161 aataaactcg taatctggaa acagttcatt tgcgagatgg attgcttttg atatatcttt
    29221 ttgtaccggt tgatgatcaa caccattcat catcaataag tggttcgtag aggcatattg
    29281 ttctgcatcc gctaattttt gcttccaaaa ggcaagagct gcttcttttt ctactggaat
    29341 ctcattcccg ttgctatacc aattggcaaa tagcagacca aagattgctg tttgatcagg
    29401 tcctttccac cacatctctg agtattggga agaatagttt tctgcttcca aaacttgatt
    29461 atcaaagcca attggtttta caccacggcc aaacgctgct gctgaaatac cagcttgttt
    29521 cattaattga ggcgtctgtc ccatatttcc aaatgtatcg ggaaaatagc ctaacatgac
    29581 aggggttccc catttacggc tttcttccat gccaatcagc atatttctca cgttcgattc
    29641 cgagctgata agaaaatcat cttgcaagat ataaaatggt ccaattctca attttccttc
    29701 attgattgct tgttggattg cctgtctttt ttctggcctt acttgaagat agtcatctaa
    29761 aataatcgtt tgcccatcca aatgaaaact gttgaaggac ggatcaactt caaatagctc
    29821 tagtagatcg tctatcaatt caatcagtcg catgtgatgc tgttcgtaag ccatgtacca
    29881 ttcacgatcc cagtggctat gagaaatgat atatactttc tttttcattt acgatacctc
    29941 ctacttttct actctaatat caaagtaatc catgactaat tcgcaaaaca tcatatttgc
    30001 ccaagaaaac cattctctcg tataattttc aggattgttc acatcgaatc cttcgtgcat
    30061 aaggtgtgtt cctgcgtcag ttgctacaag taaattcaat atccgctctt tttcagattt
    30121 gtctgacgtt gtcattcctt ccatagctaa tgcaatcggc caaacgtatt tttctggcgt
    30181 atgggaggat ccaattcctt ttgcgtactt tccttcatag aaatatggat tttctttact
    30241 caacaatgtt cttcttgttt gcagataatc ttcctcttgt tcagaacaat atcccaagta
    30301 aggtgcggcg atcagattgg gcacattact gtcatccatg actgtggcgt ttcccattcc
    30361 atctacttca tatgcataaa tcgtttgccc tttttgatta accgttcgtc cgtgattctg
    30421 aatcccctct tggatctctt tcttcaattt ctgtgtttgc tgtacaattt ctttatcatc
    30481 gagtatcgtt tgaaaaattt cttccacata acctaacacg accaccgcaa acatattgga
    30541 tggtaccaga tatccataac ggcaagtatc atcgctagga cggaaaccag accatgtcat
    30601 tcctgtaaaa gctgtttttg cacctcgccc gtcattgatc agcgtatctt cttttcttgt
    30661 cgtgtctcgt acaaatgtat aaggagagtg ttcatgatct tgctctgttt tgaacacgtc
    30721 caagattttt ttgatacctt caataaaaga ttgattgaat tgatcagttt ttcctgtatt
    30781 tttgtaaaga agataggcca actgtattgg gtagcataaa gaatcaattt catattttct
    30841 ttcccagatc caatcgttca tttttgtatg atctgtttgg tggccagcac cgttagcttc
    30901 ttcgttgaag gcattcgcat atggatcgat attgatataa aaaaattgct ttttgactaa
    30961 cccgctgatc atgtcagcta attcctcatc ttcttttgca atcactaaat aaggacgaac
    31021 ttgtgcagta gagtctctta accacatcgc tggaatgtct cccgtcaata aaaaggtggt
    31081 tccgtcattt tgctttttga ctgttgtcaa cagagtattg gcaaatgctg ctgtaaaatt
    31141 ctttgcccag tccgcatgga tatccccaca tttttgtgtg atatcttcca taaatttctg
    31201 caccgatttt ggtatatctt tataagccac taataaaacc ttctttctat ttgatatatc
    31261 tttaaagatt atacttcata cagccaatta tgtctacgct ttcaaaaaat atctttttat
    31321 ttactttttc atccattatg gtattatttg aatatgatat atcattaaga ggtgtttata
    31381 tgaatcaacc attgtaccag acaatattta atgatttgca aacggctatt ttaactggtg
    31441 aattacctgt agacagccaa ctaccaactg aaaaagaact ttcacgtacc tataaagtaa
    31501 gcagaatcac ttccaaacgt gcattgactg aattagagca attaggactt atttatcgcg
    31561 ttcgcgggaa aggcagtttc gttaaatccg cttctccgga acagattctt gcttctccta
    31621 caaaaacacg acggattctg tttcttcttc catatgtcgc tgatttgtct gttggtgatt
    31681 ttagcaaggg attgaaccct gtgatgcaag ataaacagat tgatgtcatg atgacgacgc
    31741 ttgactttct acaaaataaa acagcaaaag agctaatcaa tgaatttgac ggattgattt
    31801 attatgctct tgatacagaa caacatcttg acttactttt tgagctttca ttgaaagaat
    31861 tccctgtcgt catattagat aaaaaaatct atgagttacc ttttcctacc gttctttccg
    31921 ataatttcca aggcggtgcg cttgctgcct cttatttgat cgaacaggga cattcaaaaa
    31981 tcgcttattt gtttggtacg cagactcatc cacaatccgt tcgacagcgt taccttggtt
    32041 accttgaagc attggacaaa gctggtttga ctttccacac ttcactggat gacaaaagcg
    32101 cgacattaga tgaattgctt tcttatatca ctaagtatga agtaactgct tttgtttgtg
    32161 aaaacgatgt tgtcgctatc cagaccatga atctcttgag acagcatggt tatcatatcc
    32221 ctgaagattt ttcaattatc ggatttgatg atatccaagc agcagctctt gttgacccgc
    32281 cactgacaac catcgcacaa gattttgaac agttaggtaa gcttgcggga gatgctttgg
    32341 tcacttggtt agagacaaaa gatcgaccat ccgatagtaa atttccagtt tcattcatca
    32401 aaagacaatc aacaaaggag aaataaaatg aatatcggtc aaatagatac tagacatgca
    32461 acagcgaatc agccaaattt ctctaatggg aactgccagc cttatactgg cgttcctttt
    32521 gggatgaatt attttgcacc gcaaactacg gatcaaaacg gcagctggtg gtttcatcct
    32581 gatgaccgcg tttttcaagg ctaccgtctt acccatcaac caagtccttg gatgggtgat
    32641 ttcagtcata tgctgtttac gccgatcaat ggaaaactac aggagaacac ccttttccat
    32701 gctcaaagtt cttaccgccc agaagaaagt atattttgcc cgactcatct gtcgatctgt
    32761 caattacgtt atggcatctg ttctacattg atacctagca tgtatggcgg aatcttatct
    32821 attgattaca gcaaaaatga cagcggttta cttttatcct ttccgggacg ccatcagctc
    32881 tttgttatag atccttacac agtggaagga aaaatcacac attttgctgg ttcagaagat
    32941 cctgattttt ctttttattt tatattgaga tttgaatatc ctttaacaat tgatgagtta
    33001 gctgtttcca acaaaaatag cgactcgatc ccgttgtatt ttgaacagac aaaaaaacaa
    33061 actatccgat ttgggacatc ttttatcagc tcggaacaag cagcttataa cctggaacta
    33121 gaacaaaacc aaagcaaaga gacttacctt gctcacagtc aagaacaatg gcagtcctat
    33181 tttgatcgta tacagctcac acaccatgat caacaacaat tgcggacgtt ttatcataat
    33241 ttatatcggg tgtttttatt tccacaaaca ttttatgaaa ttgatcctag tgggcaaaaa
    33301 atccactatg atacgactag tcgatctata aaacctggtg ttctctatac aaataatggg
    33361 ttttgggata cgtataaaac ggtttatcct ctttattctt tgattgctgt agaaaaatac
    33421 gaagaaatgc tggaaggttt tttgaacagc tatagagaaa gtggctattt gccaaaatgg
    33481 ctgtctcctg atgaacgtgg acttatgcct gggacattga tcgatgcggt cattgcagat
    33541 gctgctgtaa aagatatccg acgagacttg atgcctgaat ttctaacggc aatggaaaaa
    33601 ggtgctacgg ttcaaagcaa acatccaaat tatggacgcc aaggaacaga agattacttg
    33661 acatatggct atgttcctaa tcactaccac gaatcagtca atcacacatt agactatgct
    33721 tatagcgatt tttgtattag ccaagttgcc aaggtactag aagaagagga aatgacgaag
    33781 aaatatcagc agcaatcatt gaactatcaa aatatctttg actatgagtc aggatttatg
    33841 cgttcaaaag ataaagatgg caagttcaga gaaccatttt cagctaatcg ttggggacaa
    33901 gattatgcag aaggaagtgc ttggcaaagc agctttgctg tttatcacga tttttcagga
    33961 ctgatcggaa aatatggtgg cagtgagaga tataaagaaa aactcattga gctgtgcaat
    34021 cagcccccaa cgtttgaccc aggaggatat ggttttgaga tccacgaaat gagtgagatg
    34081 gccgcgatag aatttggaca attagctatt tcaaaccagc caagttttca ctatccttac
    34141 ttgttcagtt atataggaca acctgaaatg gcacagccac tgcttaaaca gttgatgact
    34201 cagaccttcg acgattctcc aatgggttac cctggagatg aggacaatgg aagtatggcc
    34261 gcttggtata tcttcaatag tctgggattt tatcctgtca cgcctggaac cggtgaatat
    34321 gttatcggta tgccattaat tgacaaggct gttttgcttt tgtcaaatgg aaaggaattg
    34381 acgattgaag caacgcctaa tcggccgcag caacaattta tccataaaat caaacggatg
    34441 gacaaagaat atacgaaatt atattttacc catcaagatt tgctgaaagg cggcacgatc
    34501 tcttaccaat tagggatcat ccctcaccct aagaaatatc aagcaaaaga tttgcctttt
    34561 tccttatcaa actataatta acaagaggtt gtgaaaaagc tgtcctgcat caagtaataa
    34621 gaacagccaa gcaaaaatag atcctcatat ttttcgtttg gttggtctta ttaccgcaga
    34681 tgcaagcttt tgaacaccgt ttattgagag gttgtgaaat cagcgttctg acctgagtat
    34741 tagagagaca aatggcaaaa tagttcctca tattttgcca ttttttgagc taataccgag
    34801 ggtcagctga ttgaacaccg tttagtggag aggtcgtgaa aaagctgttt agtttcgagt
    34861 attaagaaaa attttgtgaa aatggctttc cacatttttg cataaatttg gcttaatacc
    34921 gagaaactgg cttttgaact ccgtttatcg agaggtcatg aaaaagctgc cttgcctcaa
    34981 gtaataagaa cagcccaaaa ttagatttct agacaatttt ttataagtta tttcattaca
    35041 ttggcttttt cttttatgat tctccactgt tttctcggta ctctttaggg gatctgccga
    35101 cgattttctt gaataattta gagaaatacg tggtgttgtt gtagccaatc tcacttgcta
    35161 tctcattgat gttttgatta ctgtgcaaaa gcagttgttt cgctttttcc atacgtaaat
    35221 ggttcaaata agctgaaaaa ctttttttcg tttctttttt gaacagctgt cctagataca
    35281 tgacatttaa atgcaggttt tctgacactt ctttgagtgt aagtggttct tgataatgct
    35341 ggtgcaggat tacgattact ttttccacat tgtcactgta ctttttctgt ctctgatgct
    35401 ttttgatgaa tgacagaagt agctgctgaa gttcttgcac cgtttttgcc tgatggattt
    35461 tttcgattcc ttgtaaatat tcctcatctt ccagatcaat caattcccgt tgaatctcca
    35521 taaacagtaa aaaactggaa tatcgtatat cttccggcat catggctgct aactgaaact
    35581 gttcaaaaaa atcagtgatc attttttgag cgacttccaa ttgtttattt tgcagcacgc
    35641 gtctgaaact tgaaaaatcg atggtttgat cttttgtttc tgcttgtact gcgtaaaaaa
    35701 catgctcgtc tttatctcca taaaattgat gcaactgtag attgtctttc gcttgttgga
    35761 atgtttcagg gattttgtcc aaagaatctg tctcttcccc gatactgatc agccattcct
    35821 gatcaggaaa gttttcttga acaaaacaac agaagccatc aacttcatct gcctccaaca
    35881 acaacgtgat caatacacgg tctccgtaat ttcgttgata gtaaaagatt tgttgccgtt
    35941 cttgcaacca tctattgata agagtatcat gagttcttgc cagttgaatc aatactatcc
    36001 tatgctgctt ctcacttatt tgtcctatta tttcttcttc acttatttca tccaattctt
    36061 cattcaacca ttgactgaat aacagttctt gatagatttc ttgttgattt ttttgttcat
    36121 tttgctgatc taaccgtgtt ttgattttct tgaggctttc aaccaattcg aacttattca
    36181 cgggtttcat caaataattc acggcgccta attgcatacc tcctttcaaa taatcgaatt
    36241 cttggtatcc tgataaaatc ataaattcaa aattatgacg ttctttttga gccgcttcaa
    36301 taaattccag tccatttatt tctggcattg tcacatccgt tactactaaa tcaatctgtc
    36361 gctgttcaag tacagctagt ccttctttgg cattctctgc tgttgctact atttgaaagc
    36421 ctaaactttg ccaatcaatt atctttttta acccattcaa aatcatgtat tcatcatcta
    36481 ccaataacac ttgatacacg ctcatccctc cttgaatgta atagaaacgg tcagtccacc
    36541 tgtctcatta ttctcaagcg acatataata actgctgccg aagctggcac gtaaacgttc
    36601 attcacgttt tgcagaccga tagaaccgtg aagttccact ttaggatgag acagtttttc
    36661 ttcaatctgt tttagccgtt tttcagtcat cccttttcca ttatctttga tgatgatcct
    36721 tacccgtttg ccttcctgca agactttgac acttagcgca ttatcgaatc gagtaaaatc
    36781 aataccgtgt ttaaaataat tttcaactaa tggctggatc acaaatttag gtacttcgat
    36841 cttttccaaa tcaggatcga tcataaaatg ataggctact cgattaggat aacgcatttg
    36901 atacaaatag acatattttt cgcaaaagtc cagttcttct tttaaagtga tcgttttctc
    36961 ttgattcgta ttgtttcgaa gcaaagcgga aaacgcatac acaacatctg ctaattcttc
    37021 acttccttcg ctgattgcat acattcggat atattctaat gtattatata aaaagtgtgg
    37081 attgatctgt gcttgaagcg cccgcatatg tgcgtcttgc tgtttgattt ctaatttgta
    37141 gatgtcttct acaaactgat tgatgctatc caacatttcg ttgataccga ttgaaagttc
    37201 cttcagttca tattccgtgt ttgttatgtc gatccgcgtc tctaaattcc ctgctgctgt
    37261 ttgatccatg gcctgcatga cgatagatac ttgctgtgaa tatcgtttga atgttttata
    37321 aagaaagata agcagtatat tgtctaaaat aatgatacca atgatcagcg gggcaagatt
    37381 ttttcccgtt tcgattttta cacttttttt atctagtaca gctaatatac gataatcatc
    37441 agacagttct tggtgttgaa caaaattgtt tttttccaga tcgtcaatcg gcaattgtga
    37501 atttttcttc agactctctg tgatgatcat ttcttgtctt tcaaacgttt ctttagctat
    37561 tttattatca tggaatgtgt atagtcgatt tgtcgttcca gaaatcatgt ataaagagag
    37621 tccattgaat gacgttagat tttctaaaat catatctagt tctttctttt gaaaaccaat
    37681 aaaaatactt cctgactcag ctcctccttg tgtgataggc aacttgatat aaaaggcgtc
    37741 tagtaatttt ggtgtcccct tttttatttc cccacctttg ttttctctag aagattcata
    37801 atactccggt agttgattca acacgatata tatcgcactt agttcttcat aatttgcgta
    37861 gagatctttg atttgatttg ggaaagaaac taattcatcg gtactgtttt gctgttcgta
    37921 tacatacatc agatactgat ctatgggttt tgttaagtag gtcgtcacat tttcgatctt
    37981 ttcggaattc cctacaagct ggtttttgat gatcctactc aaggttgttt tatcattcag
    38041 cattctgctt gtgctttgaa cggcatcact tgtcatgttt tctgcctgtt tttgattttg
    38101 ttcccaagta tggatactaa aaataacggt agcagtcatc gttacaccga tcatgataac
    38161 cgcgtatttc cgcaacagac gatttagtaa ggttcctttt gaaaatagaa tccgaaactt
    38221 attcataact ttccaactgt ttatctaatt cttcacgcca atgtgttgtc atcgtaccat
    38281 tccaaaccgt caaaagacca atgacaccaa acaggatcaa tcctttgaat tgccaagtca
    38341 cgcctaaaat tataccgcta ccaataatta tttttagaaa agacgaaaag ctggaaaaaa
    38401 ccgaaataaa acttagcttt agcagattag gaacagagat cgtatattca ctatctaaaa
    38461 tcatactgta ttgataagta gcaaataggc agagcaaggc aaaaagtaaa ataaaatcaa
    38521 tagctaaaaa aatgagccct ttgatttgaa cagataaata taaattgtaa ctcaataaag
    38581 cagtaccaga taaaaataaa ctaaatagca gattgcctct taaaaaattt cttttatata
    38641 tattccagcc tctttttatt gtgatttctt tatactcgaa tccgtacaaa taaaatagtt
    38701 cattgactgt tttccatgcc gcacctaatc caaagatgat cccgccggca aatgtatata
    38761 tccagaaata caaggttagt tttataatga cccagatccg gataaataac tcttccaaaa
    38821 ccttccctaa catatcttct cctccaaaca ttaagtttat actttctcat tatacaaaaa
    38881 aaggttgggc aatcagcacc ttgacctgat tattagagaa acaaacggaa aaatagttcc
    38941 tcatattttg tcgttttgtg agcgaatacc gagggttagc tgattgaaca ccgtttacca
    39001 agagtttgtg aaatagccgc ttagtttcga gtagtaagaa aaattttgtg aatatggctt
    39061 tccacatttt tacatatatt tagcttaata ccgagaaact ggcttttgaa caccgtttat
    39121 tcggaacaag aggttgtgac acgtcttttg tcacaacccc tttgtcttta ttcattatta
    39181 ttcttgtcgg aactcatcat attgtttttg catttctttc aataccttat catagccagc
    39241 cttgtccaaa gcgtctttca atttcggtaa tgtttcatct ggatcaacag tccctgtatt
    39301 caatccatct aaatattgat tcatgacatt agaaatatta cttaattctg ttttgacact
    39361 gtcagtgttg aagctgaatc ctaaaatcgg tgaagtttct gcatcagcaa tcgattgatc
    39421 acgtttggca atcatgtcat ccgtaataga ctcttgtgta tatagaatct tgttgtttcc
    39481 tgtattccaa gcagacatat gtgtatttgg ctgataacca tctagcaatt tgattttatc
    39541 atctgaacca tcgacttttt cccatgcttc tccctcgatc ccccaaacaa gcccattcaa
    39601 taattctgga tcactgttaa gcagccctag aagttctact gatttttctt tattttttga
    39661 agtatttgat acgacaaaat ttgccatttg tgcttgagct gtagatttta gtggaacagt
    39721 aattgctttt gagacaagtt cttgttttgc tgcatttgtc aaaattgtat cgccataatc
    39781 atacggtcct tgtgtttctc cacgcattag ccaagtattt ccttctagtg gataatcctt
    39841 attgctcgtt gcagcgtcac ttggaatgag tccttgtttg taccagctat gcattgtacg
    39901 taacagtccg atatacgttt cattatcgta ttggttgatg attttcgaat catctccatc
    39961 cagatcaata gcaaatggta acgtattccc taaaggataa tcaaagttcc cttggacttt
    40021 gaagccttgt ccaatggcaa aagctgccgt gtttggttct ttttcatgga attccttcaa
    40081 gactttttct gcatcagcgt aagattggat tccatcaatt gaaagatcgt atttatctag
    40141 taaagctttg ttaaaagtaa gtacttgttg agcaaagaca tttccattga ctgggaaagc
    40201 atataatttt ccattgacca gatttccttt aatatatgct tcatctaaat cattataagc
    40261 tttttcagcg tacttaggcg ctaattcagt caaatcagca aaggctcctt tttgggcatt
    40321 ggaaacatag ttgttcgcaa aggcgatatc ataattttcc ccggaagaaa tgatgacgtt
    40381 cattttcttt tcgtaatcgc cccagccaat gtaattgata ttgactttta caccgatctc
    40441 tttttcgatt cgtttgtttg ctacttccat caattgatcg aaattatctg gtttatctcc
    40501 gatttgatac atctgcaaag tgtccgaatt gctagcttct gcctggtctt tagaaccaga
    40561 acctccgcat gctgctaatg ttcccaacaa caacgctgaa acacctgtaa aggctagttt
    40621 cttccataac ttcatttttc ttcctcctaa ttttatgatt tatatttttg tttctttatt
    40681 cttttactcc gccgattgtt agacctttga caaaatgctt ctggaaaaat ggatagctga
    40741 tcgcaatagg caacgtcgag atgactacga tcgccattct ggcagattct cctggaactg
    40801 aggctaatcc gcctgtcaat tggcttcctg ctcctgaatt ttgtgtcaga tattgaatat
    40861 tactttggat tttcatcaaa agatactgta gtggaactag cttatcatct tggatgtata
    40921 gtaaagcatt gaaccagtca ttccagtaac ccaatgcggc aaataaactg attgtcgcaa
    40981 tacctggaac agctaacggt aaaacgatct gaacaaatat tcgcagttcg ctagctccat
    41041 cgatccgtgc cgattcaata atcgaatcag agaccgaacg tttaaagaat gtgcgcatca
    41101 caataatatt gaagggactg acagccattg gcaagatcaa tgcccaaatc gtatctttta
    41161 actgaagaag atttgtcata acaagataat tggccaccat ccctggtgag aacaacatcg
    41221 taatcaaaca aaaaacggta aaaaaacgac ggaatggaaa gtttgaccgt gaaatcgcat
    41281 aagcatataa agaagtagcc gtgctattga tcagtgtacc taaaacagta acaagtacag
    41341 tgacgaaaag cgcttggaaa attttatcct gcatctggtc gaacaagtac gtataaccaa
    41401 atatactgaa cttttctggc caaaaactgt acccgtgagt cgacaatatg gactcatcgg
    41461 taaaagagat ggcgataaca aatataaatg gcaaaataca ggaaatagca aagagtgcaa
    41521 tcattatatt agagaaaaaa ttagccgtct tattgaaaga gcggacttgg actctctcca
    41581 ctttcttttt tttcattttt ttcctcctta gaataatgca gaatcgctat caaaacgtcg
    41641 ggcgatcgta tttgtgatca tcaacaagac aaagccgaca actgattggt aaagtcctgc
    41701 agcagccgtc ataccaaaat ctcctgtgga tgtcaggcca ttgtagatat acgtatccaa
    41761 aacttgagtc acatcatata atgcaccgga attcctagga atgttataaa acaggccaaa
    41821 atcagctcgg aaaatgtttc ctacggctaa aatcgttaaa atcgtcatta gtggaataag
    41881 ttgtggtatc gtcacatgtt tgatctgctg ccatttgcta gctccatcaa ccatagcagc
    41941 ttcataataa gtcggatcga ttcccataac agatgcaaag taaataatgc tgttataacc
    42001 aatccctttc catgtaccaa tgaacaccaa gataaacggc caatatttcg gttcattata
    42061 ccaattgaca gcttctcctc catgtccagt gatccactga ttgaatattc ctttgtcagg
    42121 acttaaaaaa gcgtaaacaa agtaactgat aatgacccaa gatagaaaat aaggtagtaa
    42181 ggacatcgtt tgataaactt taacgagtcg tttatttctc aactcgctca taatgattgc
    42241 aaatacgact gagatcagca gattcaaaag gataaatgct acattatata aaattgtatt
    42301 tttagtgatg agaaatgctt gatccgaaga aaataaaaat ttgaaatttt cccaacccac
    42361 ccaaggactt tccctcaagc tagccaagaa cccatctgct gaaatatgaa aatttttgaa
    42421 tgctacgaca ttcgccatta caggtatgta aaagaaaaaa atcatccaaa gcatacccgg
    42481 tacagccatc aggacaagtg ctttataacg ccatagattc ataaaaaaat gattgaaccc
    42541 ctttcgtttt ttcatctaaa aacccctttc gattcattcg caacgtaatt atagcgcttt
    42601 caataatgag aataaataaa caaagtatag ggaaaatgaa acaaagtata ggagaggttg
    42661 tgaaatcagc gttttggcct gagtattaga gaaaaaaacg ggaaaatagt tcctcatatt
    42721 ttgccgtttt ttgagctaat accgagggtc agctgattga acaccgttta tcagaggttg
    42781 tgaattcagc gttttggcct gagtattagg gagatcgtgt ccttactatc taactctgag
    42841 tcacaaggaa caatggggac tgtaacaaaa gtcttgtcac agtcccttat tccgaacaaa
    42901 cggtgttcca gaagtagctt ctacggaaat aagccgaaat ttcacaaaaa agccatccga
    42961 aagtcagacg gacaagtctg cttttcagat ggcgctacaa ctactctgct tattctttta
    43021 gctatccatt caattatttt tctctcactt gttctagctc ttctttggtc atgggtcgat
    43081 attgcccttt attcaaatct ttaggcagcc aaaattttcc catacggatt ctttttaaat
    43141 ataagacttc ttttcctact gctttgacca ttcgcttaac ttggtgaaac tttccttcat
    43201 gcaaaatcag acggataatt gaagtttctg tctcttgatc tacttgatca atttggagtt
    43261 ttgccggcaa tgtctgctca tcgccatcaa taatcagtcc ttctgcaaat aaacggatat
    43321 cttcttctgt cattataccg ctaacctcag ctagatattc tttctccaca tgttttttag
    43381 gtgatagtaa ctgatgggca aacaccccgt cattcgttaa aatcaagagg ccctctgtgt
    43441 ctttatctaa tcggccgact ggaaaaagat cttcccgata atcctggtct tccaataaat
    43501 cgattacggt ttgatcatga ttatcctgag tagcagaaat gactcctgca ggtttatgca
    43561 aaatgtagta aaaatctttt tgatacgtaa tgatttctcc taaataagta accgcatctt
    43621 cgaattcatt tacttgcgct ttatcgcttt tcaccacttg tccattgact tcgatcgttc
    43681 cttttttgat taatcctttg acttctttgc ggctgccaag tcccatatct gctaaaaact
    43741 tatctaaacg catgcgtttc ccccatttca aaagagcatc aatctagctc ttctgattca
    43801 cttattttat ttttaattta tgtcgtaaac gcgctattcc tggtcctagt agtctttctg
    43861 ccaagcggat tttcaaagct aaataaccat acactaaagc ccctatacct gctactacaa
    43921 gaatcaacaa tagagactgg aatttgctat cttcgtttaa aaaagcacca aaaatcatct
    43981 ttgtgatcca cgaagccaaa agcataatca aggtaagaat aaagatcagc aatgtcctgc
    44041 gccagacaaa acttggttta aagcgggcta cttcatggat tctctttaag atcaaggtac
    44101 aagacacagc aaatccgatc attgtcgcca ataaagggcc gtatacttca aataaacgaa
    44161 tggctgggta ttgaagaagg agtttcacta gaaacccaat aaccaaataa ttaattgccg
    44221 ccttgttttc aaacattcct tgcagcatgt tggaaactag catatatagt cctaggaaga
    44281 gtcctacaaa acttgcttgg atcagtacat tacttcctag agaatccggt gtataaaata
    44341 atgtatttag cggataggca agtaacataa caccaaatgt cgccggaaac ataaaaaatg
    44401 aaaacaactg taaatttccg cttgtcaatt ttgccagacc tactcgatct ttcaacgtaa
    44461 cagcttctgt aatcaacggt aacccagtag acgcgatcga tgttgccaat gcaataacta
    44521 ccatcgtcaa cttatctgga ttggcactaa aaatcgaaaa aagatccagt aactgtgcat
    44581 tggaatactc ggtggatgca gacatgatct tcataaaagt gaactgatcg actaatttga
    44641 agatcgttac ccctgaaccc acaataataa acggaatcgc ttctttaacg gtatctaaca
    44701 acaattcctt cgttgcaata tttattttgt tttcgctgta gtgaataaac gccgatgtat
    44761 acgcttgatg tttcttcaaa aaatacaaaa ggacaagaat acttgctagc ataccgataa
    44821 atgccgcgaa agttgattgc gtgaccgccg tcacatagtc accatccatg actttcatga
    44881 tgatgaatgt agccaatagc atataaaaaa tacgtgccac ctgttctaca atctgcgaca
    44941 gcgcataagg catcatttct tgattgcctt gcaaataccc tcgtatcaca ctcatacaag
    45001 gaaaaaccaa tacagcgata ctcaaagaac gcatcgttgg aatcagttct tctccgccac
    45061 cagaagcatg agctagccaa ggagaggcga tgtacatgaa caaagcaaac aacaggccta
    45121 acccgcccat catctgtaat gcacggataa ataatcgtcg tgaagtgcca tattcattca
    45181 atgaattata gcgtgcagtt tgttttgcaa tcgcagcagg tattcctgct gtagagatca
    45241 gtagaaacaa tgcatatata ttgtatccca tattgaataa tccattggca gccttagcat
    45301 tttcgcccat ccaagcatac cagggaatga tatagacagc gcctagcaat cttgaaatga
    45361 tattactggc ggtcatccaa gcagagcctc gtgccatttt ttcttgcggt gttaattgat
    45421 ctaatgctgg ttttctttga ttatccatcg gtcagattcc aactttctac aaaacattac
    45481 tatcatttta attggtaaaa cagaaactgg caatcgattt tatataactt ttataagaac
    45541 aattgttttt ttgaattcgg tttcgttttt ttggtaaagt aaagaaatat acagcctttt
    45601 atggctaaca tttataggag atatcaatga cacaagaaat aaaaaaacta cccgttatat
    45661 ttttaggtct tttctttatc acagttggat tgaattggtt cttgctccct cacgatatag
    45721 cttccgccgg agtgggcgcc atcggacatt tagttgaaac ggccttttct atccaacgct
    45781 cagttactgt ttggagcatc aatcttatga tgctgcttct agccgctgtc ctattaggaa
    45841 aatcagtatt ttttaagact gtagcgggaa gtctgctttt tcctgttgtt ttagagattg
    45901 ttccaaaagt ggaaatgatc tcctcacatt tcttttcact gatttcagga agtcttttgt
    45961 tcagtcttgg ggtttacaca ttgtacacag tcggggcctc aaatggcggt ataacgatac
    46021 cgccgattat tttccacaaa ttttttcggc ttccaatgcc gcaaggactt ttacttacca
    46081 atagtcttat cgtctttttg aattattatg tttttggatt gttggagaca ctattcgttc
    46141 tcctatctat tacagtcagt tcattgttta tgaaaatact catccgcttg tcccctgtgt
    46201 caagaaaatt tgaataaagc tggattttgt catagcggaa acaaacgata tattaaaaag
    46261 agtgtgctat aataaaccaa gaaattgaat aaagcgaggg atcaatcaat gagcttctct
    46321 ttagaagaca tccgtcattt actattaaaa gaaaatctat taaaagaatt tgtttcaaca
    46381 agaggctggc atcttgatgt accagaaaaa gctgaatttc ttcagttaag ttatgattca
    46441 agaaaagctg atgcttctac tttgtttttc tgtaaaggaa tgaatttcaa agaagaatat
    46501 ttggattcag caatcgaaca gggtattcaa tattatgtat cagaacaacc atacgaaaat
    46561 tcagcagtag gaatcatcgt aacggatatc cgtaaagcaa tggcgcttct tgctatggct
    46621 ttttacgact atccgcaaaa taaattgaaa gtgatcggat tcactggaac aaaaggtaaa
    46681 acaactgctg cgtactttac aaaagcaatc ttggatcaca caacaaataa aaaaacagca
    46741 ttgctttcta ctatgaatac aacgttagat ggcaaaacat atttcaaatc ccatttgaca
    46801 acgcctgagt cattagattt atatcgtatg atgtcagaag cagttgaaaa tggtatgact
    46861 catctagtga tggaagtttc ttcacaagct tacaaaacac aacgcgtata cggcttgact
    46921 ttagatgtcg gaatcttctt gaatatctcg cctgaccata tcagtccgat cgaacatccg
    46981 acatttgatg actatttcta ttgcaagcga caattgatct tgaattcaaa aacagttgtt
    47041 ttaaatcatg aaagtgacta ttttgattta cttagggaaa cagccgatct attccagatt
    47101 ccaacgatca cttatggtcg ttcggaagaa agcaattatc aagtgatccg ttcagataaa
    47161 ggtactcacg gttttacttt atcttctcat gaagatcgct tagctatctg cgatactgct
    47221 tatgatattt tgctggctgg aggattcaac caagaaaatg cagccagtgc gatcattgcc
    47281 gcagcactaa caggtgcctc cagtcaagat gcacaagacg gattaaaaga agctcgtgta
    47341 ccaggccgaa tggatcaatt gatccaatcc aatggagcgc atgtctatgt ggactatgca
    47401 cataattatc taagcttgaa aacattgctg aaatttgcca aaaatgaaca tccagatggc
    47461 cgtgtaattg ttgtattagg cagcccagga aacaaagcaa tctcccgtcg acatgatttt
    47521 ggaaaagtgc tatcagaaac agctgacatc gcctttttga cggcagatga cccagcattt
    47581 gaagatccga aaaaaatcgc ggaagaaatc aatgaagcaa ttactaatcc agatttgatc
    47641 gttcattatg aaatggatcg tcctgaagcg attcgacgcg ctttagcaga aagcgctccg
    47701 caagattcag tcgttattgc gggaaaaggc gtggatccct atcaaaaaat caatggtgta
    47761 gatgaacctt atgaagggga ttatgcaatc gtgaagcggt tgattgaaga ataatggtat
    47821 ttatatacta gtggtttccc atttctaaga aaaaaaggga ctgtgatttt ttgtcacagt
    47881 tccttttttc ttagaaatca ttttaacttt tcactagcta attctgctgc cttttctctt
    47941 tcttcattta ataatttatt atcatagaat ttgataaatg ggaaccagat aatgaatgcg
    48001 atgattgcac aaatgactgc taacacagca gctttccaat caccaccact accaacaaat
    48061 gctccgatcc cgactggtga aggccacggc atctgtgcaa gcatcggttt gacgatttcc
    48121 agccgaatgg caaaataagc gagtgtagca gaagccatcg gagctaagaa aaacggaacc
    48181 gctaaatagg gattgtagac gattggcatc ccgaaaatga ttggttcatt gatattgaat
    48241 aatcctggta caagtgaggc ttttcctaac actttcagct gatcagattt cgcgaggaat
    48301 gcaataaaga tgatcaatcc taaagtcgca cctgatccac caacggttac ataagaattg
    48361 ttgaattctc ctgccaacgg ataatttgcg ccttgtgcgt tagctgccat attagctaat
    48421 acgatcgggg tcaagaaaga agtgatgata ttcgctccat ggatccctac gatccacaat
    48481 gcatggatca agaaataaat caccatgaca ccaagccatg tattcgtcaa ctgcgtaaca
    48541 aacccaaatg ggatagcaat cattttgaag atatccgttc ctagtgcaac taataatcca
    48601 ttgatgatca tcaccacaaa cgcaatgaca aatgttggga tcagagcagt gaaagaacga
    48661 gaaactcctg gcggaacaac atctggcatt tttatgaccc aatttctctt gacacacata
    48721 caatacaatt cgaccgcaat aatcgacata ataatagctg taaagattcc tgaagttcct
    48781 aaacgttcga caaaagagcc catcctaata ccatttacta cagtttctgt ctcattgata
    48841 gaagcaatca agctgatttt accatcagtc atgatcaatt cagggataca cataaagaat
    48901 gcaaaaacag atagtaatgc ccccgtgagc ggattaacat ttaatttttg ttcatctcgt
    48961 tcaattgacg ttaattcata agcaaacaca atggcaaagt aaatagataa aatccccatc
    49021 gtcattgtat tgacgatcat gtacaagtca ctaactttga aaaaagttgc attaaaaaat
    49081 ccttctaaaa atgggaacgg taatggcaaa atatttaaaa ccaaaaacat cgagcctaca
    49141 atcgtgaaag gaatagaagc catccccgct gccatgacag cccgaacgat tttaagttgc
    49201 gcaattttcc ccataggtcc catcaggtat ttctgcaaaa aatcaaacat tagttattct
    49261 cctttcctaa atataacgct ttttcatatt gtttaatacg gatatactgt tggtcttggt
    49321 tgagtgaaat tttctttaaa cgatactgta taaatgcact ggcaaaaata ccgcttacaa
    49381 caagaatgaa aacaaataac tgtcctccat tgttatttgc cataaaagga tacaagaatg
    49441 taaatcctga ggtaaacaac actggaatca ctaataaatt aaagacactc tggaacaaaa
    49501 aataccactt tgtccatgga acgttcgttt ggtgttttcg ataaagcttt acttgttctc
    49561 ctactgcagg caaaatagct aaaatcagaa tcatcggtaa actacttcct aaacttttag
    49621 ctgatagaag cagaatcatc cattgcatgt tcatgaaaaa gaaaaaggca gtcaggtaac
    49681 gtacgattag ataacgattg aaatacatgt ttttcaaact aagttgcttt ttttctaatt
    49741 cgattttcct ttttactgta tcctgcacaa tgatccttcc tttctattta tttttttgat
    49801 acaaataatt catttcctgt gcaacttcca ataatgtcat cgtcgtcatc agatgatctt
    49861 gtgcatggac catgataatt tccatttcta tttttgtccc gctggcatat tctttcagaa
    49921 gttgagtttg tgactgatgc gcatgaagaa tctcttcatt tgcttgtcgc aacttctctt
    49981 ctacttcttc aaacatctct ttacgcatcg agcgaaatgc ttcatgtatc agtgtccgtg
    50041 catttccgct atggaaaatg atatcaaaag aagtcacttg tagtgtttca ctgtttattt
    50101 tttcagccat ctgttttcct ccttattcga tcagtttgat aaatttactg ctgaaattct
    50161 caaaaatagg ttcagctaag atttcctgct gtacttttag ctggtcaact aacctaacga
    50221 ttgctttagt cacgaccgta attccttcat tttcgacata agaaggcgaa actaaaaaaa
    50281 caaaatgaat ttcttgatat tgatcccact gcatcccaga aggaatcaat gcaacggcta
    50341 cctttgtttc gattccaact ggaacagcgg gatgtgggac tgccactgta tcactgaata
    50401 tgatttgtcc catattttca cgttgctgga tctgctttcg catttctctt atatatcctt
    50461 cttcttcatt tatgctcagc ttttgcagca aatcatgaag aatttcttcc tttttcggtt
    50521 cgtacgtata agtcttgaaa aatttttcag acaactgttc ggtgtaaatc tgcttttttt
    50581 gctgtagaga aaatgctggt atcggtctat ctgaggaatg atagggtata gattctccaa
    50641 ctacctttcg tattttacga acatcatctt cattcaaaaa aatactgaca tgtaaaactg
    50701 gaattttgaa aaacattgtc gaaagatcaa tagaagaaat aatcaggtcg attcctttta
    50761 aagttgtttc attgatctca taatagcctt ttacacttac cactgtaata tttttaccga
    50821 attcactgac tacgcgattc tttaatagtt gggcactgcc gtaacccgtt gcacagataa
    50881 tcaatgcatg tagtttatgc gcagctcttt ctttttccaa tgccgccatg agatgcaaag
    50941 ccaaataggc ccattcatct tcattgatgg tatagttttt caaagccggc atgttgctga
    51001 aatgcctttt tactgcgtca aagactttgg gattttcttt ctttatctcc tcagtcaatg
    51061 ggttctcaat gcgaatacct cggctcaatc gaatcatcat cggtgacaaa tgatcgagta
    51121 gtccattgaa aagctggaga tcctctacta atgaaaaatg aaattcctga gacaatcttt
    51181 tcagaacttt cgctaattcc tttgatagtt cctgatcatt ttgattttct ttgtgattcg
    51241 acttagccat gagatgtaat gtcaaataag caatttcttc ttcgggaaac gatacacctg
    51301 cgattacctc aatacgttga acgatccgct gcgccacttg atactctact cgcttagaaa
    51361 cttcttgttc gatgcctaat tccttgattt caaacccttc tcggagccgt ttgatcccca
    51421 aagccaagtg taaagtcaga ttctgtatga taaaatccga aacttttaac ttagcttctc
    51481 ttgtttcatc gagaatgata atgactagct cttcaaaact gatgtctggg aaaaaacggc
    51541 tttgccctaa atattctttc aatgaatttc cataatggtt tccaaaaaaa gtatccatga
    51601 taaaatgccg tcgatttctt tcttcccctt cgatccatgt cccttgacca tgcttagaaa
    51661 cgatttttag tgaatatgga atcaatcgct ccttgatttc ttgcatgtcc tttgtcaaac
    51721 tggaacgact gatataaagc tcttctgcca aatcatccat aaaaagaatg gcatcttcca
    51781 aaagcaattg gttcaatata tacttttgtc gatcttcgga ctcataaaat ccttgcggtt
    51841 ctctagcata tccaggtact atttcttgcc gactcaaaaa caagtcaaat gtcagtcttt
    51901 gtaaaatatg cagttggtag ccataacctg gtttagcaat gatcttacct ccgttttttt
    51961 ctactaactc tttgatccgc tgcaagtaat tacggattgt ccgatcagat aataacaatt
    52021 cagaagctaa acgttgactg gtgacatact ccttcttgtg atcaatcaaa tatctcaaca
    52081 gcaatttttc cttctgtttc attatcatcc actcctattc catcatatgt tctcttcgat
    52141 cacctctgct aacttctgga tgcctgtagg gattgggaca tacgcttgga aagggatact
    52201 aacaacaggc tttccaacag attctcctaa ttttttgaat ttatccaaaa acatcgtcgt
    52261 ttgcgggctg atcagaaata aatcaaaatc actattctta atcatattat cgccttctgt
    52321 agctgaaact gcatctacga gtacctcttc tcttttttgc ttaaagaaat ccgttgtctt
    52381 tgaggccatc atcgaggatg acattcctgc cgcacaaata atcaatgctt ttttcataaa
    52441 tcaatcactc cttttatttt tataaaccaa gcatatcttg taagcgtttt ctattcaaaa
    52501 tatatatttc cgtagcattg cggaaaaaat gtgtatcata tcttgaataa taatttctgg
    52561 caccgtgata tactagtgat agaatttttt caggagggga tttagtgagt atcacagtga
    52621 atattttgta tacaagtaca aatggacaag ccagaaaatt tgcagaagaa atggtcgaaa
    52681 gaaacattgt caaagcgatt cgtgcagaag aaggaaacga gaaatatgac tattactttc
    52741 cactagaaga tccagaatct cttttactga tcgaccgttg gaaagatgaa gaagcaatcg
    52801 aaaagcatca caaatccgaa atgatggctc aaataaacga actccgtaaa aagtataaat
    52861 taaaaatgaa agtcgaacgt ttcactgatt taccgtaaaa agatacacat ggaatgatag
    52921 caatttatca tccatgtgta tcttcacttt ttccttattt tttattcgat ctcatctaat
    52981 gattcaaacc gtgtttttct cttatttttc ggataagtat ttcagtcacc ccaatataca
    53041 tgattcctaa acatacccca aggatattct caaaaatgcg gatcgttact gctcctggaa
    53101 ccccgaataa actggcagtg attgccaaag caccaaaaga attaaaaact gttttatatc
    53161 tataggtaga acaaacacct aaagctagac cacctaatat accgacccag ttaaaaggaa
    53221 taaattggct gataccaata aataaaacac atccaatcaa tgagccaatg attcggtcta
    53281 ctgctcgttc tttgaaacca atcgacatca atccatagct agatacaata gaagaaaatg
    53341 caaaccctgc ccacatcaat cgctgaaaag ggacatactc tcctgcaacg atcaaaagac
    53401 taatgccaaa tgcatagatg agcatccaaa ttttttcctg cgaatacatg cctttcaaaa
    53461 aaatctcttt aaacaagctt ttgtctttgt tcttttctcg atgttttctg taaaggagaa
    53521 ctgaaaacca acaaaaaaac aaaaataata agctacttgt ttgtgtaaag aaattcttgt
    53581 tcaacgaatc tttaggtaac gaataaacaa taaagagata tgaaaagccg tacaaagaag
    53641 cattccccat tttgggatca ctagcggttg ccattaatat gctgcttagt aaaataaaat
    53701 gaatcaacat gcccataact gaccatttga tcagctggac atacggtgct actaatagtg
    53761 agaacatgac gattgctaaa cctatgatcg aatgggaaat cttataacca aagtcaacaa
    53821 aacgaatact catcaacata cagaataaaa ccacagcgta tggtttatgc ttcgattcaa
    53881 ataatgttgt aattataatg ataaaacaaa tggcaaacaa tacgatgaat aatgatcgta
    53941 aaaacaatga acaaatatac atgcactttt cttttttaga agctgcttct cgtatttttt
    54001 gttttaaaat aaacggatct agttgtagag actgataaaa atccacctgt tgtcgtcctt
    54061 tctttttact tttatttttt acagtcatct atgacaggtt gtaaatacta tggaacatca
    54121 tatggcgttg tcattttctt gtcaactatt tttcctattc atgtttttat aaaaaaacat
    54181 atcgttttct tgtatgatta aatcaccaca aaataaacaa ctgagagaac gatatgcttt
    54241 atgaatggtt ctatcaaaaa aattctgaga tcaatagaca aaaatttgat gattacagag
    54301 gtctcttacg aaaccttaca gaagaaaaaa acattgatcg ttgctgcagt tctcttccct
    54361 gctccatgtg tctgtagaaa ttgtggttct gctgtggtag atggaaatag gaaattaatg
    54421 gtggtgaaaa acaagaagaa ggaaaccatt gtccactttg aataatataa tcatatgcca
    54481 atggttatac gcctaaaaaa gcagcgctat acctgtaaaa actgtcgaag ccattggaac
    54541 gctcaaagtt attttatccg tccaaggcac tcgatttcaa atcatgtcag acataaaatc
    54601 acttctttac tgactgaaaa agtgtcgtta ttttttattt cgaaaagttg ttaggtatct
    54661 ttgacaaccg ttattcgcac attgaaagag ttgagaagct atttaccaaa gtcttccaaa
    54721 agaattctgt cttgagtgtt gagggttgtg aatttcgttc tcacgtttcc gttgaggata
    54781 aactgagttt tatttccgcg gatggcgaga cagaaaaatt aatcgagaaa atttacctac
    54841 acaaaaaatt cctcgattaa caaactattt ccttagctgc actaatccta aagaaataga
    54901 attcttagtt acagacatga acgccaccta ctttcagctc accaaacatg ttctaccaaa
    54961 tgcgaaattg gtgattgatc gattacttgg tttttccacg cctttcaagg aggcgtaacc
    55021 tttattcacg agttggttga agctttccga gacaaaagac ccgacttgtt tttctcctta
    55081 ttgacaaaga gccattaaaa ctagagaaaa aattacaact gatcgctgat tatttgtaga
    55141 aagaaaatca aagtattacc caataaactt gagtcattag gcaaaaaaca ctgcgaaact
    55201 caagaatgat tttcgcagtg tttttgtata ttttttatta actagtatta ctacaaaggt
    55261 ttatttttca cttctcaacg cagcacaaaa ttgtctttac ttatttactg gttgggttca
    55321 accttctcta ctccgatact aatatttgtt tgtatacccc ttctaaaatc ggtagtttcc
    55381 attcaattga tgggtactag ttgattttaa aaactatgct tattcaattt tttattttag
    55441 ctcatatatt tcgtttcttt ctaaatttta tactgatgaa aacaagtagc acacccaata
    55501 ttgacaatat aaactggcta atgatggttt ctccagtttt tggaagatgc ttatttccac
    55561 tgcttgttgg attgtttcct cttatatctg agctatcagc aacttttcta ttctcttttg
    55621 ttaaaaagat cgccacttct tgttcttttt cgatcttgaa agttactggt gtcgcatcca
    55681 attcataccc cgttggcgct tgagtttcta ccagctgata tgctcctggt gctaagccat
    55741 ctatcgccag ttttccatct gctcctgtgg ttagacctga ctgcagaacg gttccattgg
    55801 catcttgtaa ctcaaaaaca gctccttgca ggacttctcc gctttggtca tcgatctttg
    55861 tcaacacgac accgcctggt gtaagtcgat tttctttcgt caattctacc accgctgtct
    55921 gacttctttc gatctcaaac tcgattggtg tcgcatccaa ttcatacccc gttggcgctt
    55981 gggtttctac cagctgatac actcctggtg ctaagccgtc aatcgccagt tttccatctg
    56041 ctcctgtggt tagacctgac tgcagaacgg ttccattggc atcttgtaac tcaaaaacag
    56101 ctccttgcag gacttccccg ctttggtcat cgatctttgt caacacgaca ccgcctggtg
    56161 taagtcggtt tgctttcgtc aattctacca ccgctgtctg acttctttcg atctcaaact
    56221 cgatcggtgt cgcatctaat tcataccccg ttggcgcttg agtttctacc agctgatatg
//
LOCUS       DADVXM010000010        50044 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.010, whole genome shotgun sequence.
ACCESSION   DADVXM010000010 DADVXM010000000
VERSION     DADVXM010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 50044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50044
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.010"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            115..960
                     /locus_tag="KB927_000687"
     CDS             115..960
                     /locus_tag="KB927_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6839624.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1241..2461
                     /locus_tag="KB927_000688"
     CDS             1241..2461
                     /locus_tag="KB927_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBB6839625.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2458..5178
                     /locus_tag="KB927_000689"
     CDS             2458..5178
                     /locus_tag="KB927_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6839626.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5162..6106
                     /locus_tag="KB927_000690"
     CDS             5162..6106
                     /locus_tag="KB927_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6839627.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6175..7185)
                     /locus_tag="KB927_000691"
     CDS             complement(6175..7185)
                     /locus_tag="KB927_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6839628.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7365..7709)
                     /locus_tag="KB927_000692"
     CDS             complement(7365..7709)
                     /locus_tag="KB927_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBB6839629.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7702..8136)
                     /locus_tag="KB927_000693"
     CDS             complement(7702..8136)
                     /locus_tag="KB927_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBB6839630.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8274..9011
                     /locus_tag="KB927_000694"
     CDS             8274..9011
                     /locus_tag="KB927_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6839631.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9004..10215
                     /locus_tag="KB927_000695"
     CDS             9004..10215
                     /locus_tag="KB927_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6839632.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10419..11201
                     /locus_tag="KB927_000696"
     CDS             10419..11201
                     /locus_tag="KB927_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBB6839633.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11271..11933
                     /gene="trmB"
                     /locus_tag="KB927_000697"
     CDS             11271..11933
                     /gene="trmB"
                     /locus_tag="KB927_000697"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBB6839634.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12031..13785)
                     /gene="ade"
                     /locus_tag="KB927_000698"
     CDS             complement(12031..13785)
                     /gene="ade"
                     /locus_tag="KB927_000698"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBB6839635.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            13917..14846
                     /gene="tadA"
                     /locus_tag="KB927_000699"
     CDS             13917..14846
                     /gene="tadA"
                     /locus_tag="KB927_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBB6839636.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14803..15852
                     /locus_tag="KB927_000700"
     CDS             14803..15852
                     /locus_tag="KB927_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBB6839637.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            15849..16127
                     /locus_tag="KB927_000701"
     CDS             15849..16127
                     /locus_tag="KB927_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBB6839638.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16102..16572
                     /locus_tag="KB927_000702"
     CDS             16102..16572
                     /locus_tag="KB927_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBB6839639.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16589..16891
                     /locus_tag="KB927_000703"
     CDS             16589..16891
                     /locus_tag="KB927_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839640.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            16908..17279
                     /locus_tag="KB927_000704"
     CDS             16908..17279
                     /locus_tag="KB927_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBB6839641.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17251..17610
                     /locus_tag="KB927_000705"
     CDS             17251..17610
                     /locus_tag="KB927_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839642.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17782..18789
                     /locus_tag="KB927_000706"
     CDS             17782..18789
                     /locus_tag="KB927_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6839643.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18814..19998
                     /locus_tag="KB927_000707"
     CDS             18814..19998
                     /locus_tag="KB927_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBB6839644.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20435..22018)
                     /locus_tag="KB927_000708"
     CDS             complement(20435..22018)
                     /locus_tag="KB927_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6839645.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22596..22739)
                     /locus_tag="KB927_000709"
     CDS             complement(22596..22739)
                     /locus_tag="KB927_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBB6839646.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(22962..23441)
                     /locus_tag="KB927_000710"
     CDS             complement(22962..23441)
                     /locus_tag="KB927_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6839647.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23514..23798)
                     /locus_tag="KB927_000711"
     CDS             complement(23514..23798)
                     /locus_tag="KB927_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839648.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(23876..24070)
                     /gene="ssrS"
                     /locus_tag="KB927_000712"
     ncRNA           complement(23876..24070)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KB927_000712"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24142..25428)
                     /locus_tag="KB927_000713"
     CDS             complement(24142..25428)
                     /locus_tag="KB927_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBB6839649.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25566..26237
                     /locus_tag="KB927_000714"
     CDS             25566..26237
                     /locus_tag="KB927_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBB6839650.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26203..26691
                     /locus_tag="KB927_000715"
     CDS             26203..26691
                     /locus_tag="KB927_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBB6839651.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26704..27651
                     /gene="prmA"
                     /locus_tag="KB927_000716"
     CDS             26704..27651
                     /gene="prmA"
                     /locus_tag="KB927_000716"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBB6839652.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27652..28416
                     /locus_tag="KB927_000717"
     CDS             27652..28416
                     /locus_tag="KB927_000717"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBB6839653.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28649..30862
                     /locus_tag="KB927_000718"
     CDS             28649..30862
                     /locus_tag="KB927_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBB6839654.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            30873..31319
                     /locus_tag="KB927_000719"
     CDS             30873..31319
                     /locus_tag="KB927_000719"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBB6839655.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31490..32749
                     /locus_tag="KB927_000720"
     CDS             31490..32749
                     /locus_tag="KB927_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBB6839656.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(32838..33785)
                     /locus_tag="KB927_000721"
     CDS             complement(32838..33785)
                     /locus_tag="KB927_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6839657.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34179..35471
                     /locus_tag="KB927_000722"
     CDS             34179..35471
                     /locus_tag="KB927_000722"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBB6839658.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35486..37255
                     /gene="aspS"
                     /locus_tag="KB927_000723"
     CDS             35486..37255
                     /gene="aspS"
                     /locus_tag="KB927_000723"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBB6839659.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37364..38239
                     /locus_tag="KB927_000724"
     CDS             37364..38239
                     /locus_tag="KB927_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6839660.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38505..40388
                     /locus_tag="KB927_000725"
     CDS             38505..40388
                     /locus_tag="KB927_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBB6839661.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40463..40747)
                     /locus_tag="KB927_000726"
     CDS             complement(40463..40747)
                     /locus_tag="KB927_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6839662.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40737..41471)
                     /locus_tag="KB927_000727"
     CDS             complement(40737..41471)
                     /locus_tag="KB927_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBB6839663.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41600..42223
                     /locus_tag="KB927_000728"
     CDS             41600..42223
                     /locus_tag="KB927_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBB6839664.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42415..43536
                     /locus_tag="KB927_000729"
     CDS             42415..43536
                     /locus_tag="KB927_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBB6839665.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43543..46671
                     /locus_tag="KB927_000730"
     CDS             43543..46671
                     /locus_tag="KB927_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBB6839666.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46690..49884
                     /locus_tag="KB927_000731"
     CDS             46690..49884
                     /locus_tag="KB927_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBB6839667.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLQELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
BASE COUNT        16412 a         8755 c        10438 g        14439 t
ORIGIN      
        1 tcctattctt aaaatgatgt ttgtacttac ttaaattagg tataattagt atatgttttg
       61 tgagaaattt agacttacaa taagcagtga atttataatc aacgtatagg agacatggat
      121 gaaatgaaac taattggtat agatttagac ggtactcttt tgaattctga ccagagcatt
      181 agtcaaaaaa atgcaagaac aatgaaacat ttaccggaag actgttttcc attcatttgt
      241 tctggaagag aagtagaaga cattaataat attctcaaaa aatctggttt aaggatacca
      301 gcagtagggt taaatggttc tgttggattt gatggagaaa aaaagatatt tgagtcttcc
      361 ttcgataaaa atgatgtaaa aaaaattgat tctgtcctat cgaaatttcc aaccaaaata
      421 tatacaaatc tcggaagtta tgaatctcag aattataaaa ataaaatgaa aaaaattttt
      481 cacgaggtag ggagtgaatt ttctatcaaa gagctaaact atgagcttga gtatgaaaaa
      541 tctatttgtt caatccctta taataatatt gaggaaatta tagaaaagga tgctatcagc
      601 atttacaaat tttttatttt tattcctaat cgtcaattga aagctaatat atttaaccat
      661 ttgaaaaaga tgctaaatgt gtctgttact gaatcggcac ctgtaaatat tgaaatcgta
      721 cctcaaaatg tatctaaagg tgtggtgttt gatcgtttgg aatcaatcta caatttaaag
      781 aaacctttga gaatcgcgat cggagatagt ttaaatgact tatctatgtt tgaaagtgca
      841 gatattagtt ttgcaatggg aaatagtcat caagaaatca tgaaaaaagc tgattatgtc
      901 actgtttcaa atgataaaga cggagtatct caagcatttg aaagaattct taccatataa
      961 actaattaag gtagtataga acatagaatt ctaaatacgg aaaaatggag cataaattcc
     1021 agtacaaata gtacttcttc agtgtcaaac gaagcgaata taacatagat atttaggatt
     1081 gtgacaaaaa tcatgtcaca atcttttttt cgaataaact tattttttga agtcggccat
     1141 ttatcgtaat ttctttgcat aatacgaaca aattttcggt tattgatgaa aaaaaacatt
     1201 gaaaatggta tgataaaaga aaaaaaggag gaaattttta atggtgaaat ttatccatgc
     1261 ggcagattta catatggatc ggtcatttga aggactgaca actcttgata aaactgtaca
     1321 ggaaaaacta ttgaagacga atctgaccgt tttatcaaat atcattgaac aggcaataat
     1381 aaataacgtt gattttgttt tacttgcagg agataatttt catcaaaatc gtccttcatt
     1441 aaaaatacag aaacattttt cagaacagat gaaacggtta gaaaagaacc atatacctgt
     1501 atttataata ttcggaaatc atgatttcta tcaaaaagag cggtattggt tctcctttcc
     1561 taaaaatgtc catttattta catccgaaac ggtagagaca aaaaaaataa cgataaaaag
     1621 tggagaaact gtctctctca gtggatttag ttatcgtcaa ccgtggattc aaaaagacaa
     1681 agtgatggaa tttccttcta gagaactcac agattaccat attgggttgt accacgggga
     1741 acctggcgtc tctcaaaaag gaaactatgc tcctttccaa ccctcaaaga tgcaagaaaa
     1801 gggatacgat tattgggctt tagggcatat ccatgtgcca acggtcttaa atgaaaagca
     1861 aacaattgtt tatccaggtg cgcctcaagg tcatactaaa aaggaacaag cttctacatc
     1921 tattctacta gttgaattaa gtaaaggaag ttgccaaata catccgatta aagtagcaga
     1981 ggtctattgg aagacaaagg aaatatcatt gaggaaagca agaacgacaa aagaggtcat
     2041 tgttcacatt cgtcagcagc tttcaaaagt agaggatgga tttagtttaa ttgagataaa
     2101 attaaaagat tatgaccatc tcaatacaga tgttttggaa cggatacaat caggagagct
     2161 attagactat ttgttagagg aattctcaga taggataaat gatttcttta tttggcgtat
     2221 ttctctcata gagaatactt tttatacgaa gaccccactt gctgcttctg ctaaattgat
     2281 ggaacagtta tttcaatact atcagacacc tcaagatttc caacaaattt taaatgaagt
     2341 atatagtcat caagaagcgg ctagaatatt gagcgaactg ccggaatatc aagaagaaac
     2401 acttgaaaaa gccaagcagc tgcttaatca agatttttta tttgaggagg atcaggaatg
     2461 aagattttaa ggatcgagat tgctgctttt ggaaaatggc gtcaaaaaag ttttgacttt
     2521 tattcaggca atcagctgat ctatggggga aacgaagcag gaaaatcaac gatttatcaa
     2581 tttattcaag caatattatt tggtttccct tcaaaaggcc gtaaaaaaaa ggattataca
     2641 ccaaaagacg gctcagccta tggcggcaaa atatggctta aacatcctgt atatggtgaa
     2701 tttgctgtcg agcgctacaa gcagcaaaat cgcggaaaat cgaaggtgtg gctgggggat
     2761 caagtgggaa gtgatgagtt actagaaaaa ctgatcgcac ctttgacgaa agagttattc
     2821 cagcaggtat ttactttcca gcaagagcag ttgatggaac tagatcattt gagagaaaaa
     2881 gagctacatg atgcgctgat ttctttaggc atcacgggca gttctcaagt attccaaaag
     2941 cggcaagaat attatcagaa agcacaacaa ttattcaaga aaaaaggcca aaaattacta
     3001 atcaatcaaa aattaaatga atggaaagag ctgcaagaaa aaattcatca aaaacaagaa
     3061 caggaagctt attttggcaa gttgatccaa caagaacagg aatacgagtc gcaacagcag
     3121 cagttattgg cacaattaaa agaggcgaac aaacaatttt cattagccag acagcaagaa
     3181 cttaattttt ctttatatga agaatggcaa tctctcaaaa aaaacagcac tacaggtctt
     3241 cctgatgagc aacttctttt agatctggag tctttctcca aacggtatca gcaaacaaat
     3301 gagcgtttgg aagaattaga agcaacactg gaaaagcata gcgggatgga tcagcagtca
     3361 gccagatatt atttttattt agagcaggag caggaactaa aagatctcca gcaacttcaa
     3421 tttacagcgg aacaattaaa cgaagaatgg caaagattac aaattgagac tagagaaaca
     3481 aattcagaat tgaagatttt ggaacaaagg tggcattggc agaaaaatcc gttaccggaa
     3541 gaatttttat atgaagaaga atggaagcat cttctggctg aagaaagaag gattgctgat
     3601 ctagaaagcc agatttctgt gcgtctccaa atagctaaag aacagcaaga gatgattgaa
     3661 gcagaagtga atgacttgga agagacctat ccagcattat tacaaaatca gtcagagata
     3721 gcaccagtct cttcatctaa accgtatatg ctgatggctg gcggagcaat aatcattgca
     3781 ggtatatttg taccaatgcc cttgaaagtg atccttttac taattggtgc aggcatgatt
     3841 ggctatttct tctacaaaag gcaaccaaaa attaaaacta aaaatgattt ctctgagata
     3901 aaaggaatgt ggcaagaaaa actaggacaa cttgatctag ccttagctca attagctgaa
     3961 gcagaagaaa aacaaaagag aactggagaa gaaaaacaga ttcttcagca agaagtatat
     4021 cgttttgcgg atcatcggca cttaggaaag atggatacgc tcaaactcat gaaagaatat
     4081 ggacaggaag tcatagatta tcagaaatta tatggcgtat ttgagcggaa acataaaaga
     4141 gaacaggaaa tacaagaaaa actacgacaa atcgaccaaa aatttgagtt tgttaaagaa
     4201 tggttaccga tacaagataa gacaatttca gaaaaaatgg tattgctttc ccgttttata
     4261 caagagatgg aacagatgaa atttgccaga agctatcagc aaaatacttt attgaagcaa
     4321 gaaatcaatc aattgaaaaa gaaacaaaaa gtatggatac aagaatacag cgaacaattg
     4381 actcaagcag gcttatctta tccttcggaa gtacctgtct ttttacaaaa agccaaacaa
     4441 gccgaacagc agatgaaaag atacaatgaa ttatcggaaa tgcttactcc actatttcct
     4501 gaagagctga caaaagagaa attatctgta agactgcgcc aactgaaaga aaagcaatcc
     4561 caactccagc aagaagaaaa agaagcaagt gaaaatcggc aacgactcca acttcaagta
     4621 gaagagttgc aaagagacgg cacattggac gaactttatc aacaagctag ccggcaaaaa
     4681 gcaaaattac aggaattact ggaggaatgg ggagcacttg aaatcgccgg gacattctta
     4741 ggtgatcttt caacagagat gagtgaaaga caattacccc agttgttaag agcagcaggt
     4801 gattatttag gtattttaac aaaaggaaat tatcagaaga tattactgaa aaatgataca
     4861 ctgactttaa cagacggata tacagaattt cccatctatg agttatctac aggtacgaaa
     4921 gatcagctga ttatggcgat gagatttgct tacctctcat tagaagctaa ccgttcgata
     4981 tgcccgatca tcattgatga tggctggctt cattatgatc atcagcgaaa gtatcaatta
     5041 gctgaacttt tagctaaatt tggagaaaag tatcaaataa tttgtttttc ttctgataaa
     5101 gaaatggtaa gctattacca tgagatgaac caaatcgtaa aacaattaga aggagcaaat
     5161 aatgaaaaaa attcgtgatt tagtaatcga tgagcagttt gaacaatttg tcctgatcaa
     5221 aagtgcagat gtaagaatcg ctaaaaacgg aaaaaaattt attgctttta ctttccaaga
     5281 tacttcaggt actatcgatg gtaaatactg ggatgcttcg gaggaggaaa tcaataaatt
     5341 tacagccggc acagtcgttt ttctaaacgg taaaagagag gtttatcaag gaaaccctca
     5401 agtaaagatt cttcatatgc gcttaacaag ggtagatgag ccaggagagc ctagtttata
     5461 catggaaaga gcccctttga agaaagaaga aatggaagaa gaaatcaatc aattgttgtt
     5521 tgagatcacc aatgcgcatt ggaatcgtat tgttcgctat ctacttaata aatatcaaaa
     5581 acaatttttt gagtttccgg cagcaaaaag aaaccatcat gcatttgcca gtggattagc
     5641 ttatcatact ttgacaatgc ttcacttagg gaaatcaatc gccgatgaat atcctgagct
     5701 gaatcgagca ttgttgtatg ctggtatcat tttgcatgat ttaggaaagg tgattgaact
     5761 ttccggtcct atgtcgacag aatatacgct tgcaggaaat ttgatcggtc atctggtatt
     5821 gattgacgaa gaaataacta aagcctgtct tgcgttgaaa atcagcgaag ctgacgaaga
     5881 tgttctcgta ttacgtcata tggttttagc acaccatggc ttattagaat atggctcacc
     5941 tgtacgtcca agaataatgg aagcagaaat attacatcaa atcgacaata tcgatgcttc
     6001 gatgcagatg atgttgactt cgattcgtca aacagaacca ggaaaataca ccgatcggat
     6061 tttcggtatg gacaaccgaa gtttctatgt accaaaagat ttatagcaaa aatttatttt
     6121 tttcattcaa aacaaaaaaa gcgagacata agtcttcgct ttttttgttt tcttttattt
     6181 tgatgaatca gttgtttctt cagttgaaga ttcttttgtt gaatcagttg attttgtgtc
     6241 agaactcttt gttgaagctg tagtttcact tgagtctttc gtacttgatg aagttgttgt
     6301 gaatgcactc aacacatttt caaaggcatc atctttgatt tttacatttg catcttttaa
     6361 ttcttcaccg attactttag ttgtgaatgc attgtcactt agtttagttt cagtagcgat
     6421 atcttttagt tgatctttgt atttatccat gtcattgcct ttattttggt ttttcaccat
     6481 tttgacaacg tagtattctg tcgcataaga agtaggattt gttgtagtaa taacatcgga
     6541 gatctcaccg tctttcaatt tgaaagctgc ttcttttact tctgcaggaa tagttgttgt
     6601 cgttgagtcg aatttaactt taccgccatc ttcttttgtc tctgtatcag ttgatttgtc
     6661 tttggctaat ttagagaaat catctccatc atccgctgat tttttcacat cttttgcttc
     6721 atcttcactt gataatttga tgatttgtgc ttctacttct ggatggaaag atttccaagc
     6781 agttttcaaa tcgtcatctg taatatctac gtgagctttc aagccagctt caaaagctaa
     6841 attgttacga atatattctt tataagtatc tttcgtatat ccagcagctt ctaattgtga
     6901 ttcaaaagta tcacctaatg atttcgcttg tttgtcgtat tctgcatcca cttgcttatc
     6961 ggttacttta tcgccatatt tgttattgaa tactttataa atgatcatcc gttgtactaa
     7021 ggattggttc gatgattcaa gttttgcttc atcatagaaa tcagatacag tgatcgttcc
     7081 gcctttcatc gttgcgatat ctttattagt atcgcctgaa caagctgcta gagttaaaac
     7141 agccaacgca ctagtagctg ccaaaataat tgattttttt ttcattaaaa tttgcactcc
     7201 tgtaattagt tattattttt atatattaac tataccatat cccatttcct ttaaaaacgt
     7261 tgtcgtggta gtttcaaaca aaattcaaaa tttcatcaca ttcctaggaa atacgcaaac
     7321 ttttctcact tatatagtta aatctgttga gaaaataatc attattatat ttgttcagga
     7381 tactctggca gatcagcttt tagtttttct acttgttcat tgatttgtgt gatacgtggt
     7441 tcggcttgga atttaaaatc ttcgatatct tttttgattg cttcttggaa agcaggaatc
     7501 acagattcag ctgtttcttt tgtttcgatc aatgcgcttt taaaatgatt caggctgtta
     7561 tttaaatcat ttgtcagagt tgttgcttct tccaattctt cgatcagttt ctttcttgtt
     7621 tcattcccgc tcctgggcgc caataacaga cctccgacag tgccagcagc agctccaaat
     7681 aacagtcctt tgaaaaagtt tttaatcatc gcaggacacc tgctttacga ttgtttcttg
     7741 aatagctttt agttcttccg atccataact atcttgatga ttgacaaagt gaatagaaaa
     7801 atcatcctct ttgctgtagc gagggactaa atggatatgt gaatgaaaaa cagattgata
     7861 ggctagttca cggttgttat tcaagatatt aagacctttc atttctggaa aagctttttc
     7921 caatgcttga gcaatcttag gcacacgcga aaaaacctct cctgcaagtt cgggatcata
     7981 ttcaaaaata tctgctacat gacgtttagg cacaactaat gtgtgtcctt tcgttgcttg
     8041 agagatgtct aaaaaagcat agaccttgtc gtcttcatat attttatagc ttgggatttc
     8101 ttgattgatg attttgcaaa aaatacagtt ttccatataa aacatccttt ctataaagaa
     8161 taaatacttc agcttaactt taccataagt taaagctatt gtaaggaaaa aaacaaaata
     8221 ccgtcatttt cttcgtggta taataaataa aaataaatgg cggaggaaaa agaatgagtt
     8281 taattatcga tcatgtcaca ggggggtacg gacatctccc tgtgttaaaa gatatcagtt
     8341 tcgatgtaca gcctggagag atagtagggt tgattggact gaacggagca gggaaaagta
     8401 cgaccatcaa gcacattatc ggtctgctgg aagcttcaaa aggaacgata gaaatcaatc
     8461 atctatcctt aaagaaaaat acggaagaat atcgcaaaca aattgggtat attccagaga
     8521 ctccttcttt atatgaagaa ttgacattga gagaacatat cgaagtcact gcgatggcct
     8581 acgatatacc tatggatata gcaatgaaaa gagcagaaaa gttgttggag acttttcggt
     8641 tatctaatcg tcttgactgg ttcccagcta atttttcaaa gggaatgaaa cagaaagtga
     8701 tgatcttatg cgcctttttg atcgagcctt ctttatatat catcgacgaa ccatttttag
     8761 gcttggatcc actagctatc aatgcattgc ttgaattgat ggtagaaatg aaaaaagaag
     8821 gagccggtat tttgatgtct acgcatattt tagctactgc agaaaaatat tgtgatcgtt
     8881 ttgtggtctt acataacgga gagatacgag cagacggttc tcttgagatg ttgagaaaag
     8941 aatttcagct gccggattct tctttggacg aaatctatat tgctttaaca aaggagcagg
     9001 cacatgagta gtttttttca aaaacgttta gcaagacatc aaaagaaaat gatgaaatat
     9061 atgcgttatg tattgaacga tcattttgtt ttagtttgtc ttttcttgat tggcggtgtg
     9121 ggattatatt attctaattg gttgaaaacc ctgcagccac cgtttgcaat tggagggctc
     9181 ataatctctg tattttggat gctctgttta ttcgtgggta agatggctac ttttgcagag
     9241 gcagcagata ttgttttttt acttcctaaa gaaaaagaaa tgcaaaccta tttggaacga
     9301 gcttttcgct attcttgcat ttttccgttg atctttttga tattggcatg cggattggcc
     9361 atgccattag tggtggttag tacggagcaa tccttttcga tgtttttcgt ctatctgatc
     9421 atattatgga gtttgaaatt cagtcatctg caaatcaaga gagcagaatt gtttcgacta
     9481 gatcaacaag ttattcgtta ttggaaatta ggctggtttt tttcttctct gatctttttg
     9541 tttctatcat tttattggct aatatgggca ggaatagcag gtgcattagt acaggcaagt
     9601 ctatattact ggtttttgtg gaagcaacaa gaaaaaggat tggattggga gaaaatggtg
     9661 catgtagaag aacataggtt gcatcagatc tatcaattta tcaatttatt cacagatgtt
     9721 cctgaaatta cggcaaagat caaaagaaga cgctatttgg atcctatatt gactcatatt
     9781 aaaagagaat caaaaaacac ttatctttac ttgtttgcaa gaagattggc aagaggttct
     9841 gattttagtg gtctttattt ccgattagta attataggtg ggttattgat tgccggagta
     9901 gtcgactttt attttagtct gattatcggt ttcttatttt tatatttgat cggtttccaa
     9961 ctgttacctt tagcgaacca gttccgctat atggttctcg ttcagcttta tccaatccat
    10021 aagaatcaga agaagcaggc gattcagtat ctactcacat gggtattaat tatcgcgtcg
    10081 gttatttttg gtttgattgc tgcagtcgta ttagatgggc agcagcgatg ggttccgcta
    10141 gcggcttatt tgattgttac tatgctcttt gttaaactat atgtaccaac tcgtttgaag
    10201 aagatgtcag actgaaaaca aagctgtgta gggtaaaaat gagaatgaaa aatagagcgt
    10261 tgacagtaag aatgctgttc gttctatttt ttttgagaaa agctggtttt ttgaatggca
    10321 attaaatgaa aaagaacgta tatgtgcttg acgtgtagtg ttcaggcgac tagaataata
    10381 agtactgcaa aacaaagagt aagaggacgg gagaatgcat gatggagttt cagttagacc
    10441 aagagtggcg gttacgtccc atcaaaggcg acacaggaaa aacatacata ggcatgcgtg
    10501 atgaggacaa agtctttatt aaacgaaaca cgactccgat gttggctgct ctttcaaggg
    10561 aaggaattac accaaaactt gtttggacaa aacgaacggg gaatggcgat actttgacag
    10621 cacaagagtg gctggaaggt cgcttgctga ctcctaatga gattggtcaa agaaacgacg
    10681 tgattgatgt tttgtaccat ttacatcatt caaattctct taaaaccatg ctgacccgta
    10741 tcggtggtcg tgtcatgacg ccggagaaga tgctgcaaaa atatgaaaaa gaattaccgg
    10801 aagaactcca gaaaaatcaa tttctgcaaa ttgtccatcg ttttcttcgt gagcagatcc
    10861 cgtcaataga taaggaaaac ttatcagtag tacacggaga tgtaaaccat cgtaattggt
    10921 tagtatgtaa aaattattta tatctagtcg attgggattc aatcatgttt gcagaccctg
    10981 cggtggatat tgcaacgatt ttaggaaatt atgtgccact gtctagctgg aatcagtggc
    11041 tgatcagtta tggcatacgc ccgactgacg aaatgcttga aaaatttcat tggtatgcgg
    11101 ccatgaattt gctccaagaa atcaccagat attgcaaacg tgaagatcat cgacggatga
    11161 acgaagaaat tttacaatta aaacgaattt tcagtggctg aggtttggcc caaactctgc
    11221 ggagatttgg ccagaccttt ttaattagag gaaaggaatg gagataaata atgcgtgtcc
    11281 gaaatcgtcc gggagcagcg gaaatgttag cggctcaccc gaattttgta attagtgatc
    11341 caacattgtg gaagggaaaa tggaatgaat tgtttgaaaa cgatcatcca atccacattg
    11401 agattggtat ggggaaaggc cagttcatca ctggaatggc aaaagcccat cctgaaatca
    11461 attatattgg agtagaaatg caggtcagtg ttgtttcgat tgcactagac aagttgatcg
    11521 aacaaccgct tcctaacctg aaacttctac atgtggatgg atcagcgttg acagagtatt
    11581 tcgctgacag cgaagtagat caaatctatc tgaatttttc cgatccatgg ccaaaaaaac
    11641 gtcatgaaaa acggcgattg acatataaga cttttcttgc tgtagatgaa cagattcttc
    11701 gtccaaatgg agaaatccat ttcaaaacag ataatcaagg attgtttgag tattctctgg
    11761 caagtttttc tcaatatggc atgatcctca aacaggtatg gttagattta catcaaagtc
    11821 aatttgaagg caatattatg acggagtatg aagaaaaatt ttcttcaaaa ggtcaacgta
    11881 tttatcgagt agaagctcaa tttcaagata agaccaaaaa gaaaagtctg tgaaactaac
    11941 tttctgcttt cataaaaaca ttaatatcca taaataaatc ccagaaaatg aacattacag
    12001 atgtaatgta ttttctggga tttatttgat ttaaaatgta tttatttcat cggtttttcc
    12061 acaaggtgga atcaattgga agcgagaaaa tgaaaataat cctttgtcgg tgatcttcaa
    12121 ttcgggtatg acagataatg ttaagaaaga aagtgtcaaa aaaggatcaa aggttttagc
    12181 tgctcctagt tgatgtgctt tagttattaa ttcattcaac tgttcataga cgatcgaaaa
    12241 aggttcctgt gtcatgattc cgcctatagg aagagaaaca caagctattt cctgctgttt
    12301 gttgacaacg gtcatcccgc cacctttttg aatcaaaaga ttagcagcat acagcatatc
    12361 ctcgtcgttt gtcccaacga caactagatt atgcgagtca tgggcaatcg ttgtcgctat
    12421 cgctccttgt ttcagctgaa atcctttcac tatgcctaat ccaatgtttc ccgtttgatg
    12481 gtgacgctcg atcaccgcaa tctttaattg gtctttttcg attgaaggaa tgaatcgttc
    12541 gccttgtcgg tccacttttt ctaccaaatc tttagtcact agactattcg ggataatttc
    12601 gatcacatgg gcttgtgaag aagaaagaag cagctctaac gaatgtggat ttaatggttg
    12661 agcgtttagt tttggcagac aacacgtata tgaatttgaa tgatcagcaa ataaatggtc
    12721 ttggagttgc ccagattgaa caactaatgt tcccttatag aaaacttcat gaattggcag
    12781 cttggtaaga tcgtctgtta agaagaaatc agcttgatac ccaggggcaa tcgcacctag
    12841 tgttttcaaa tcaaaacatt ctgctgcatt caatgttgcc atctgaatgg cttgtaatgg
    12901 atcgattcca agtgcaatag cttgacggac gatatgatcg attgatcctt cttttactaa
    12961 atcattgatc agtttatcat cggtgacaaa gaagcatctt cttgaatttt caggtgtgat
    13021 cgccggtagt agcgatgcca gatcttttgc aacggtccct tctcgaacca ttaaatacat
    13081 accaagatcc aaacgttctt tagcttcttt tgcagttgta gcttcatgat ccgtccgaat
    13141 acctgctgca ggataaacat ttaactcttc catgccgata ccagctgcat gcccgtcaat
    13201 ttttttctta tgctggtgca tcaattggat cttttctagg atgtctgttt cattatttgc
    13261 tactgcttga tagttcatga cttcagctaa gcctaaaact tcgggttttt gtaaaaaagg
    13321 ggctaatttt tttgcattta aatttgcacc attggtctca aaaggggtta caggtacaca
    13381 agaaggtagc ataaaaaaga tattcatgag tgtttgtctt gcatcttcta tcataaactc
    13441 aagacctgta ctcccagcaa tgtttcctat ttcatgggga tctgtcacta cagtagtaac
    13501 tccatgaagc aaggatactt ttgaaaattc gcttggtgat aaaagtgagc tttcgatatg
    13561 cacatggcca tcgatgaatc ctggcactag atattgccca ttagcattat gtacgctttt
    13621 tccttcgtat tcaccgattc ctacgatcat tccttcgcag attgctacat ctttttccat
    13681 gatttctttc gtaaagacgt tgacgatctt agcatgcttg atcactaggt cagcaggctt
    13741 ttttttactt gctacttcga tatatttcct taatgttgtt tccaatggag tgcctcccaa
    13801 gataaatttt tataagtata acataaattc ggtttttgcc aatatttttt tgtaaattca
    13861 ttttatttga aacaaaaaga tcaaaaagac gtatgttttt tgtggagggg agaataatgg
    13921 aaataaaacg attatcggat caaatgataa gtgaaagttt tgccaaacat gcccaagacg
    13981 tatatatatt gccagcttca gaagtatttt acatctattt tcgctatgga aaaaaacgaa
    14041 cattctggaa gaaagtctct tcggcagatg gacagcaact gatctcaaga tttaagtatt
    14101 tgggacagat ggatatcgga gaaaaaagaa aagctcagtt aggtgcattt acttattctt
    14161 tagaaaaaca ggaagttcgt ctgcggttgt cttctgtagg agattacctt caacgagaga
    14221 gtttagtgat tcggctatta tacggtactt ttgaaacacc ccatcgttgc tttagttctc
    14281 gagattttgc aactatttta cagaaaaccg tcagacgtgg attatacctt ttcagcggac
    14341 cagtcggatc aggcaagact tctctaatgt atcggttggc tttggaagaa aaattgcaag
    14401 tgattactat cgaagatcct gtagagatag aagaaccgtt ttttctgcag ctacagatca
    14461 atccgaaaat agcacagact tatgatacac ttttgagact cgcattacgg catcgtccag
    14521 acttgctaat cattggcgag ataagagatg aatcaactgc acatgctgcg gtaagagcag
    14581 cactaacagg gcaccgggtt tttgcaaccg tacatgcacg caatcttgaa ggtacattgg
    14641 tcagaatcca tgaactgaca aagaaaaaag aagagctatc tgaatgttta gctggtgtca
    14701 tttatcaaga acttttggaa gatgccaatc accatccttc tgttttatgg agttatcaat
    14761 ttatggagga agaatcagta aaaaaatcat gggaggaaag ttatgaagaa gctcaggaaa
    14821 atatttggca gtcagaacta ttctaaagga ttaacaagaa gccagcaaaa ccagtttgca
    14881 caaaccatgg gagaactgct tttatctggt tttagtctgc aagaatccct ttatttatta
    14941 ctcacgatcc gttcgtttcc acctgttatt ttggcaaata tccaacatca gctaaaggaa
    15001 gggcaagcgt ttagtgaggt actttcgcaa ataggatatg gagcagagca actggtacag
    15061 atcgagttag ctgaacgtca tgggaatctg ccgacaactt tgttggaaat tgccaaacag
    15121 tttcggcttg ttgaaggatt tcgcaatgat ttgaaaaagc tgcttgcata tccgatgcta
    15181 ttgctcacct ttttgctagg tatcttgttt agtatgcggt tgttcgtttt gcctcagctt
    15241 attggttcag gaatggtcat gcaagagcat tggggtattc agctgataca agtctttcat
    15301 tggtatgttc tactattcat cctagcggtt actctattgg ctttactagt aaggtatcgt
    15361 ctgatgaagt tgtctcctgt tgatcagagt gaatggataa gcagacaatt attgattgga
    15421 ccgatatatt ccttgtatca atcggcttat ttgtcactag agattggaaa gctttttcat
    15481 gaaggtttcg aattaaggca aatcatagtc tgcttaaagg aaacgaaaca agaaagtctg
    15541 attcagcatc ttgcctctaa gttgattcaa ggattggagg caggtatgtc attggctgag
    15601 cagttccaga attatcgttt tctatcagaa gaattcagta aaattgtttt acagggagag
    15661 gcaaagggaa gtttaggtaa agaactgatt ttttacagcg aatggacaag aaaacagctt
    15721 ttcaaacgtc ttcatcactg gatgcatttt attcagccaa tcattttttt gggcgtagcg
    15781 gctttgattt tattagttta tgccgctgtt ttattacctg tttacggaag catagaggag
    15841 gttttgccat gaaaaagaga aaaatatctt attatagcgg ttttacattg atcgaaatgc
    15901 taatcgtctt actgatcatc agtgtattag tgttgttgtt cgtccctaat ttgtcgcgtt
    15961 ataggaatca tgtagaccaa gaaagtcgtg aagcgatcat ccagttggta gacacacaaa
    16021 aagagctcta tgcgcttcaa aataatggaa gagttcctac tgtggaggaa ttgttgaatg
    16081 aaggctatat caaacgagaa catgcagaaa tctatcagcg gccttgaagg taaggtttta
    16141 gcatcaggat atacgttgtt tgaatcactc ttactgattt tattacttac aacgatcctt
    16201 tcttttccag ttctcgcatt ttctgcatgg aagaatgaat tggcagtcta tcaatttttc
    16261 ggccaatttg aaaaacgaat ctattctacg caaaaaatcg ctattgtgaa tcagatccaa
    16321 acaggctttt attggaatag tgaagagaat caaatcattt ttcatgttcc gaatccagat
    16381 aaaataaatt gggaagtatt agatattcct gatgagatta ccttgaaacg ccatgcttct
    16441 attacttttg ctgctagaac cgggaatgaa agttcactaa aagcttatca attttattgg
    16501 gaagaaaaag agcggacgat tacgtatcaa ttccagatag ggagtggtcg ctatacaaaa
    16561 agaattgaat aaaacaggat ttgttttgtt ggagtccctt acagcgctta tgatcgcttc
    16621 tgtctgtgtc tacttagtga gctttggcca gctgtttttg cttcaggcag aaaagaaaag
    16681 tggggaggaa ctgctattta ttcgaatgat ttatgaagat atcaagacgc agcggatgta
    16741 tcacaaaaga ccagagcgaa gggaagaaat gatcccatac gatatccaaa ttgtcgataa
    16801 taatggagta atcgaaaaag tgtttgtcaa tatggagaaa gaagcgatca gtattgaaaa
    16861 aacaagtaat tccagcattt acgctgattg aatgtctaat tggactgatg atattgagca
    16921 gtctattgct cacattcaat cttttgattc agcaaaccat ccaagtaagt gaatttttgc
    16981 agcgtaaaga tcaaaaagag tggctaatat ttttagcaca attagaagaa gaactcaaga
    17041 gcagtcacaa tgtctctgtg aaaaatcagc aactgcacta cacgatcgag gataaacagt
    17101 atatcatcga aagatatcag gcaatgatac gtaaaagaag aacttccggc ggacatcaac
    17161 ctatgttaac aagtatcact gagcttcaat tattggaaaa agaacacaca atttcttttt
    17221 atgtacactt tgaaaatgga gaagatggat atgccatatg gacaaaaaac gatcagtaga
    17281 aaatgttata agggctctat tttattttct gtcttgcttt tatttctttt atgtacgttt
    17341 ttattgatgg cagcattaga aagctaccgt ttgtcaatgg atcttaatat acgaatcaaa
    17401 aattattata tagcaaaaat aatgaagcag atggctttat cggaacagtc tacgcttgcc
    17461 gaaagttcgg aaggagtttt ttactacaca actggatctg taacatatca gtgggtacaa
    17521 cagtccctat tcttagaggt ggaagtctca ccgtttatct ttcggttcac agaagaagta
    17581 aaaaatgata cagatactag tacagaatga tggaatgttc gtgaaaacgc cctcttttct
    17641 gttataacac tgtttttaat aaaaaaatgt ttgccgtttc acaaataaaa aacagtgaaa
    17701 acgattgaaa ttttgtcaat tgttcgatag aattaaacag gtgaaaaaat tgttataata
    17761 tatctagaaa tgaggtgcac catgttacca gaaaaaatgg aacaagggtt taatcaaaac
    17821 ctggaagcta ttcagctttt acagaatgca ttgggaactt cctttttaga agcctatgtc
    17881 gaaaatgcag aaaatttaat agatgattat caagtacgtg tggtggatgg agtgccgaca
    17941 aaagagacaa cgcaacggat cacagctctt tatgaagagt tgaagaaact ttctttcgag
    18001 ccagaagaat ggcgcagact gtctcaatta cttttattga agggcagcca gacagaacat
    18061 ttgcaggcga accatcaact cactcctgat agtatcggtt ttttatttgt ttttcttatt
    18121 gaacaactat acacaaataa aaaagcaccg gttaagattc tggatattgc ggcaggaatg
    18181 ggcaacttgt tattaacagt tcttttaaac ctatcgaatg cggggtacca aacagaagga
    18241 attggtgtgg atattgatga tacattgttg gctgtcgcag cttctacaag tgatttgaca
    18301 caagcaaatg ttcaatactt tcatcaagac gggttgcagg aattattaat agatcctgtc
    18361 gattttgcaa tcagcgattt gccaatcggt tattatccga atgacgaaaa agcaaaagag
    18421 tttttaacaa gtaccgaaga aggccatagt tatgcacatc atttattgct agagcaatca
    18481 atgaaatatg tgaagccgga tggttttggt ttgtttttga tgccgagtgg atttttagaa
    18541 acggatcaaa gtgaagaaat caaaaaatgg tttaaagaag aaggttatct tcaaggaatg
    18601 attcaattgc cagatgaatt gttccgtaat aaacaatcgc aaaaaagtat tttgatctta
    18661 cagaaaaaag gaccacaagc acaacaagta aaagaagtct tgcttgtgaa acttgcttca
    18721 ttaaaagaac cagagaaggt gacggaattt ttcaacgagt ttaaaaactg gaaatcatct
    18781 gctctgtaat cattcaacga gaaggagagt catatgtcta aaacaattgc aatcaatgct
    18841 gggagttcaa gtttgaaatg gcaattatat caaatgccag aagaaaccgt agttgcgaaa
    18901 gggatcgtcg aacgtatcgg tttacaagat tctattttta ccatcaagta cggcgataat
    18961 caaaaattcg aacaaatcat ggatatcgaa aaccacgaag tagcagtaaa aatgctgtta
    19021 gatcagttga ttgaactgca aattttaagc tcttatgatg aaatcaccgg agtagggcac
    19081 cgtgttgttc acggaggaga aacttatggg gattcagtag tgatcgatga gaaagtaatg
    19141 gaccgcattg ctgaattagc agaatttgct cctttgcata atcctgcaaa cttaatgggg
    19201 atcaaagcgt ttaaaaagat tttacctgac attttgagtg tggctgtatt cgatacatct
    19261 ttccactcaa caatgccaaa gcaaaattat ttatatagct taccggtgtc ttattatgaa
    19321 gatttcaaag taagaaaata tggcttccat ggcacaagtc atcgttatgt gtcggaacgt
    19381 gcggcaaaat tattgaacaa accgatcgaa gaactaaaaa tcatcacttg ccacttagga
    19441 aatggtgtat cgatcacagc agtcgatgga ggtaaatcca tggatacttc tatgggattc
    19501 acaccattag ctggggtgac aatgggtaca cgttcaggtg atatcgatcc agctgttctc
    19561 ccatatttaa tggaaaaatt agagattgat attgatgaaa tgatcaatgt tttgaacaag
    19621 aaatctggtc tgctaggcct aacaggattg tctagtgata tgcgtgatct tgaaaagaac
    19681 tatgaaaaag aacatattcg tttagcttat gacattttcg tggaccgcat ccgaaaatac
    19741 atcggcggtt atgtgacaac gatgaatggt gttgatgcaa ttgtctttac tgctggtatc
    19801 ggcgagaatg acggacatgt acgtagtgaa atcatcaaag gtatgtcttg gtttggttgt
    19861 gaaatcgatc cagcgttgaa tgaattgcgt ggtgaagaag tagatatctc tacaaaagaa
    19921 tcaaaagtaa gagtattagt gatcccaaca gatgaggaac taatgattgc ccgtgatgtg
    19981 gagcgtctgc gcggctaagc caaagcattc gttaggataa aagatgaaac gcatgcaaga
    20041 gggaattctt gcatgtgttt tttttgcgga gaagaccgca aaatggtaat ttaacttcaa
    20101 tttcccttct tttttacagg atcttcttag ggaattttgc ttggaaaagt ggtcaaaagg
    20161 gaaaagactg gcattttatt tattgatttt caggaaaatc ccaatatttt attttcattc
    20221 atctttataa gggacattac atatgtaaaa agaaaaaaca tttttagatc agcctcgtgg
    20281 gctgtcgact ttattcttcg ctttatgttt agctagaaaa ccgatccgaa acattcattg
    20341 atcgaataat aaaaacttga ttttccacct gtactttgcc tgaatcgtga aagcacaggt
    20401 atgaaaatca agttttttgt tgcgaaaaaa cgtcctagtc aatcagttgg ccgagcggct
    20461 ggcggctgat ctgctcctga tcaataacga gtgcttcttg gaagtgttgc tgcaaaaagt
    20521 agcggtcatg gctgactgct aggagcgttc cttgatagtc ttgcagcatt tcttcaattt
    20581 cttctcgagc atagctgtcg aggtgattgg ttggttcatc caaaatcagg acgttgattt
    20641 tttctaaaaa gagtttcagc aacgccaaac ggattttttc accaccggat aaatctttga
    20701 tccgtttacc cacatcgctt tgataaaagc cacttttggc taattgccgt cgagcgactt
    20761 cttcgtttcc agtcaatgtg atggcgtaag ccagcaaacg gctatcggga tcggcaaact
    20821 gcagctgctg cggcaaataa ccgatttgca agctactacc taatttgatg gtgccaccgt
    20881 aaggcttttc ctcaccgagt aataatttga gtaaggttga ttttcctgca ccattgtcgc
    20941 cgatgatggc taaatgatct ccacgataga ctgcaaaact gctgtctttg aatagtactt
    21001 gatcagcgta ctgctggtgc aagttttgaa tgatgaaaac ttctttgcca gattttccac
    21061 cattagacaa gctttgcagc cgatttttcg ggggaggtgg cggtttgacg agtgtcagtt
    21121 tcgccaggcg gcgttccagt tctttggctt ttttgaagaa ggactcattg tctccttcat
    21181 gtgcccactg acgaaaacga cgaatcatga ctttcaaccg ctggacttct ttttgctgca
    21241 gttcgtaatt ttttgtcagc tcagccaagc gagcttcttt caagactcga aaacggctgt
    21301 agtttccggg atactcaatc aatgcacctt cttccagttc ccatgttttt gtggtgactt
    21361 gatcgagaaa ttgccgatca tgagaaacga ccagaaccga tttttttgta ttctgtaaat
    21421 agttttccaa ccagcgaata ctgttaagat ctaaatgatt ggtcggttca tcgagtaaaa
    21481 gtaaatcggc atcggctgct aaaattttgg ctaaagcgac tttaactcgt tcgcctccgc
    21541 taagttctgt taaccgtgct tcctgacggt gtggaatccc taagccttgc aagatcgctg
    21601 caatccggtc ttctaatacg taaccgccta gttcttcaaa gcgatgctgc agctcaccgt
    21661 aacgggccag acacttctct aagtttgtat ctggttctgt catcaatgct tcgtagcgac
    21721 tcatttgctg tttgaggtcc tgtatctcag cggcagaatg gagcaagtag tggttgacgg
    21781 tcgcttcgga aactgtaagt tcttgttcga ccgtcccgat ctttaagcct tttttgcgac
    21841 tgataacacc gctgtcgaca ccttctctgc cggtcaagat ttgtaaaaag gttgatttgc
    21901 cagttccgtt gataccgact aaggcaattt tttcaccagc ttcaatttga caggataaat
    21961 cctcaaataa tggattcccg ccgattgttt ttttaataga aattgcttgt atgatcatga
    22021 tctctctcct tgagaccact caaaaaggcc atggttatcc atggcctgtg ttatttaaac
    22081 tcagattatc atgagaaaaa taccttgaga tggccattga ttttacgtga attcaactgt
    22141 tttggacaaa cttgtcccgt caacagcaac tgtaaaacca attgcatggc taaatgcgat
    22201 atggtatcgt tggtaatttt cattacttgt tattttagtc atgcgcatca tagtattttc
    22261 cctccttcgt gtagttgtct tttccagtgt acctgaaagt gtcagaaagt tcaactagcg
    22321 ctgacattta cttaatattt atcgatgtgt aattctgtca gagagctttt tttatctgac
    22381 tgagggtaat gtctcgtgga ccacatcatt gtattctgag ctaaaccagc gttcaggcga
    22441 aatcatatgg tgtttgataa aaaactttgt ctacatgact tccttttgcc atttgcttaa
    22501 taccgttgca ttaaacagct cttctctttg gaaatctcac caacatcgcg ttcaggagta
    22561 tcgttgtggt tgcaatggca agcggtagcc tttcatcaat tcttgaatga tttaccgaat
    22621 gtagcacttg ccttctcgcg gtacccgaac ccgaaataaa attttagttt ggcgataaaa
    22681 tcggtatccg ccatcgatac ttcatatttt ttcgtatcag attcatcgga aacttccaca
    22741 ttgacgaacc aataagcttt ggcatgctta ggtcgtttta aaccacacca gggcgactaa
    22801 tcgccctggt gttcactttt ttttatttta cttgaactca ttgactgttt tccctttatt
    22861 ttaaacatta taaagaccga tgagtgcttg ccgcgtcttt tgtttttatc acggtttttt
    22921 gtgcaaaaaa acctgccgat agttggcagg tcgtctacgt gttaagcttt ggtgtggtct
    22981 ttagctggca attggttttc taaatcagtt cggacaacaa gcacatcgca agctgcgttt
    23041 ctaataacat attcagaaac agaaccaata aataaacgtt ctacagcatt caatcctgtg
    23101 gctcctaaca taatcaaatc tacttgatta tcttctggga tttctctggc aataatttgt
    23161 tttggtgagc catattctac gacagaggtt acattattca agccagcttt cttcgcattg
    23221 ctttcataat ctgccaatgt ttgctttgcc atttcagtag cttgttctgc aagcattcca
    23281 tcaaaggatg aaacggtttg gaaagaacgt gtgtcaatga catgtgctaa tagaagttct
    23341 ccgttatttc ggatagctac attgaccgcc tttttaaaag ctaattcagc ttcatcagaa
    23401 ccatctacgg caaccatgat ttttttgtat tgttgtaaca taagcattca ctcctcaagt
    23461 caatcgtatt gtactctttt attgtagaac actttaggga aaaagagaat tatttactgc
    23521 tttggttcag caattttttt tgcaaatcgg atactgaagg tggcagaaac aataattacg
    23581 atcagtaaaa agaccaaggc aataaagcgt tgattgaaaa aagctgttaa aatacccatt
    23641 acgcctaaaa cagcatatgc agctccgtaa aattgtagga atccttgatt tttatcattt
    23701 ttgttgatca atacaaaaaa gatatcctgt ttattaaata aataatagct aacgaataat
    23761 aatactaaag tggcgataat cattaaaatc ctaatcatga acaaatcctc caaaataagc
    23821 aacaaataga aaaagcaatt tgccaagagc aaattgcttt attctttaaa agatggtaat
    23881 ctccgttaat gccgttgttt gtcctgtagt attgatcccg cgaattcaag caggtgggtc
    23941 ccatggtcgt agcttcgaac taccaaatga taaggcatgt taccagcagt gacacaagac
    24001 gggtcccaag atatcaataa aaatgttcgg tcaacacaca aagaggacaa ttcgaacatc
    24061 acagatttcc cacctctata gtagcatatg aatttaaaaa gagcaatgag agagctcgca
    24121 gaaacagaac cgttttcttg tctagttttt tggaggatgc tttttccact cttttatacg
    24181 gtaatactgt tgacccagag cctgttcata tttccctgta tcttttggct gataatactg
    24241 agcattcttc agtttatctg gtaaatattg ctgattgacc caagcctgat caaaatgatg
    24301 aggatactga taacccacgc cacggttgag tgatttcgca cctttgtaat ggctatctct
    24361 caaatgatca ggaacatctc cagctttgcc ctctcgaata tcagcaagtg ctgcatctaa
    24421 tgccatgtag gcagaattgg attttggcga caagcaaaga tcgacgacga cgtctgctag
    24481 tgggatacgt gcctcaggca atcccaattt ttcagcagct aatacagcgt tcactgtacg
    24541 agccgcagca gcaggattac ctaaacctat atcttcataa ccgataacca tcagacgccg
    24601 gcaaatactt gccagatcac ctgcctcaac taaacgggcg agataatgaa gtgcagcatc
    24661 cacatcactt ccacgaatcg atttttgaaa agccgaaata acgtcataat gagcatctcc
    24721 atttttgtca tgggtaagag cttttctttg gacacattct tcaatgatcg acagtgtaag
    24781 atgaatcctt ccttctttat ctgaaggagt cgatagtgta gccagttcca gcccattcaa
    24841 tgcactccgc aaatcgccgt tcgttgcacg cgaaaggtga agaagagcat cttcgtctaa
    24901 ctggattgct tgttgtccaa ggccgcgttc tttatccctt aaagcatgtt cgactgccaa
    24961 ctggatgtct tgttctgtta atggtttgac ttcaaagatc tgtgtacggc tgcggatcgc
    25021 tggattgatg gtaatataag gattctcagt agtcgctccg atcaagatga ttcggccact
    25081 ttctaaatga ggaagcagaa aatcctgttt tgttttatct aatcggtgta cttcatccaa
    25141 taagaggatc actgtaccac tcatttttgc ttcttccgct acaacttgta gatccttttt
    25201 tgaatctgta gcggcgttta gcatgcgaaa tgcataatta gtagagccgg cgatcgcact
    25261 tgcgatactc gtttttccag taccaggagg tccatataga atcatggaag agagcatgcg
    25321 agcatcgacc atgcggcgta tgatttttcc ttccccgact agatgctgct gaccaacgac
    25381 ttcatcgatc gttcgaggtc tcatgcgata agccaatggc tgttgcatag gattttcctc
    25441 cttcttgttt ttacgtccct taattatatc atatttagca agatgcctag aaagaacagc
    25501 cttctgttgt tttgttttca tagcttatcc aactaatatt gtgtatgata aagtaggtga
    25561 gaaaaatgac ggataaacaa aagatagatg aatttttttg gaataaaacg acgccagaag
    25621 tggcacggga tttattgggg atgtatttgg agcatgacac accagaagga agattagctg
    25681 gatatattgt agacgcggaa gcatacctag gtccagaaga cgaggccgcc catagctatg
    25741 gtttaagaag aacaccgcgt gtgcgggcaa tgtatgaaaa accaggtacg atctaccttt
    25801 acacgatgca tactcatcgg attttgaaca tcattactca gccagaaggg attcctcaag
    25861 gagtaatgat acgtgcaatc gaacccgccg caatgattga tcaaatgagt aaaaatcgtg
    25921 gcggaaaaac tggtccagat atcagcaacg gtccgggaaa attagtggaa gcattagcaa
    25981 ttcctcaaga actttatggt cagtctatag cagatagttc gttacgctta gtttttgaga
    26041 aaaaaaagac accaaaaaag atcaatgctt tgcctagaat cggtatccca aacaaaggtg
    26101 tatggacaga aaagccgttg cgttttgttg tgtcgggaaa tccttatatc tctttacaaa
    26161 gaaaaaacca aatcgagaaa gattggggtt ggaggaaaga aaatgaaaaa gaaggatcta
    26221 ttaacatatt tagatgaaat aattgaaaaa caagtgacag actatgatgt agctttagat
    26281 tgggatacaa aaaatcatac gatcgagatc gttgttcgct tgtttgcaga aaataaagca
    26341 caatttgaga ttgatgatgc agaagggatc gtttcgcaag aaccaattat cgaatttgaa
    26401 gacggcgtac ttctttttaa tcctcagaaa tctgtttttg atgaacgcaa ttatctagca
    26461 gtaatccctt atgaaggaaa aaaagggttg gcaaaatcag tagctgattc tttagtggaa
    26521 tatctaaatg aagtattagc tcaagggcaa agcgatttgc ttgatttttt ggatgaagac
    26581 gatgacgaag ctgtattcga gcttcactgg gataatcagc aactagcaga attagtagaa
    26641 gtaaaacagc aaaatgaagc agatacttat ttaccgtacc caagttatta aggagtgaca
    26701 gatatgaaat ggaatgaagt aaaagtagaa actgaaagtg aagcagtcga agcagttgct
    26761 aatattttga tggaggcagg ggcgagtggt gtcgcgattg aagattcttt agatgttgaa
    26821 cattttcagt cggatcaata tggtgagatt ttagataaaa atgattttac atcgctgaaa
    26881 gaaggcgcac tagtcatggc ttattttccg gaaacgactt tcttaccgga aatcttgcct
    26941 tttatcaaag atcgtatcac acaattacct gagtttggtc tagctattgg aaaaaataaa
    27001 gtaacagtta gtgaagtaga ggaaagcaac tgggcaacag cctggaagaa atactatcat
    27061 ccggtgcgta ttacgcgaat gctgacggtt gcgccaagct gggaaaacta ccagacagaa
    27121 gatcctctag aaaaaattat cacactagat cctggtatgg catttggcac aggcactcat
    27181 cccacgactt ccttgacatt gacagcacta gaaacagtct tgcgtggtgg tgaaacattg
    27241 ctagatgtgg gaactgggtc gggcgtgcta agtattgcag caaaatatct tggtgcaaaa
    27301 gatgtctatg cctttgattt agacgaagta gccgttcgtt cggcgaaaga aaatatggat
    27361 atgaatgaaa tagccaaaga tgtccatgta tcagctaacg atcttttgac aggaatcgag
    27421 attgaaagtg atgtaatcgt tgcgaacatt ttagcagata tcatcttatt gatgatccca
    27481 gatgcttggc gtttactgaa gcaaacaggc acgctgatcg tttcaggaat cattgaagag
    27541 aagaagcaaa tggttctgga tgccatgtta gaacaagggt ttatcgtgga tcaaattttc
    27601 cagcaaaaag actggtatgc aattattttg aaaaaaccag aggtggaata gatgcagcgg
    27661 tattttttaa aagaatcata tgaatcaaaa gactattttg ttttagaagg ggaaaactat
    27721 caccacattg tacgggttat gaggatggaa cccgaggatg aagttttttt ggcattcaat
    27781 gatcaaatag ccattgttgc agaaatcacg gagattactg aagaggctgt ttatctgaaa
    27841 gaaattaaaa aagaagaaaa tcaaaaggaa ctgccaagtt cgattaccat agcgagtggc
    27901 tatcctaaag gggaaaagct ggattggatc gttcagaaat ccactgaatt aggagcgcaa
    27961 gcttttcttg gtttcccggc atcagcctct gtcgttaaat gggatgcaaa aaaacgtatg
    28021 aaacgacaac aacggcttga aaagattgct caagaggcag cggaacaatc ccatcggcag
    28081 atcgtgccat cagtagagtt attggaaacg aaacaagatt tatttgagcg gctagatgat
    28141 tatgacgtgg tcttggttgc ttatgaggaa tcagcaaagc aaggcgaaaa atcaaatgca
    28201 gccaaaattc ttagtgaaac aaaaccagat agtcgaatct tagctgtctt tggaccagaa
    28261 ggtggattat cccgcgatga agtcgattat tttgtagaac acaaagggat actttgtgga
    28321 ttaggaccaa gaatccttcg tacagaaaca gcacctcttt atttattaag tgctgctagc
    28381 tatcaatggg aattaatgaa tccttctttc agctaacgtt cttcattaat aaaagagtat
    28441 cgacagaaag aattgaaaaa atagtcaaca atttgtataa tagaaacaat tatttataca
    28501 atggatacga aaaatcgttt gaaaaagctt ttaaaaagcg aacatttccg taaaaaaacg
    28561 tataactgca cggattttgg gacaattatc aaacagatat ttgtcccgat tcccgtttta
    28621 ccgaaaaaag aaagggggat cgattcctgt gacaaaagaa gaaattttaa cgggacccgg
    28681 tgtcataaag ctcgttagtc aatacatggg tcccgaacat gtagcatttg ttgagaaagc
    28741 atgcgaatac gcgactgctg cacatgacgg acagtttaga aaatcaggcg aaccctacat
    28801 tattcatcct atccaagtcg caggtatatt agcagattta aaaatggatc cccatacagt
    28861 ggctacaggc ttcttacatg atgttgttga agatacagaa atcactttag aagatctgag
    28921 agaagaattt ggcgatgacg ttgctatgtt agtggacggc gtaaccaaat tagggaaaat
    28981 aaaatataaa tcccacgaag agcagctagc agaaaaccac cgaaagatgc tgctagcaat
    29041 ggctcaagat ttacgagtta tcatggtcaa attagctgat agactacata acatgcgtac
    29101 gttgaagcac ctgcgagaag ataagcaaag aaggatcgct caggaaactt tagaaatcta
    29161 tgcgcctctt gcacatcgtc tagggatcag ccggatcaaa tgggaattag aagatacagc
    29221 acttcgttat ctaaatccaa aacagtatta ccgtatcgtc cacttgatgc agacgaagag
    29281 agaagaacgt gaaaaatacg taagtggtac tgttgaagat attcgaatag cgacagaaga
    29341 gctggggatt tttgcagaaa tctatggacg gccaaaacac atttattcaa tctatcgtaa
    29401 aatgaaagat cagaaaaagc agttcaacga aatttatgac ttgctagcta ttcgagtgat
    29461 cgtagattca atcaaggatt gttatgctgt attaggagca atccacacaa aatggaaacc
    29521 aatgcccggc agatttaagg attatattgc catgccaaaa gctaatatgt accaatcttt
    29581 gcatactacc gtgatcggtc cggcaggaaa tccggtagaa attcaaatcc gaacacagga
    29641 aatgcatgaa atcgctgaat tcggggttgc tgcacactgg gcctataaag aaggaaaaaa
    29701 tgaaaaagta gaaccagatg gtatgacgaa acaattaagc tggttccatg agatactcga
    29761 acttcaagac gaaagctatg atgcttctga atttatggaa ggcgtaaaag gagatatctt
    29821 tagtgataaa gtctacgtct tcacaccaaa aggagacgtt actgagttac caaaaggatc
    29881 cggaccattg gactttgcat acagtatcca tacagatatc ggtaacaaaa ccactggtgc
    29941 aaaagtaaat ggcaaaatgg tgcagcttga ttacaaattg aaaaacggag atatcattga
    30001 gatcatgact tctccaaatt catttggccc aagtcgcgac tggttgaaat tagttgctac
    30061 tagcaaagca agaaataaga tcaaacgttt cttcaaagcc caagatcgag aagaaaatgt
    30121 gatcaaaggc cacgaatccg tggtcaaatg tattacagat ctaggattta cgcctaaaga
    30181 tattttgacg aagaacaaac tgcaagaagc actcgatcgt tttaattatc aaacagaaga
    30241 tgatctctat gcagctgtag ggtatggaga agttagcccc ttgacgatgg ccaatcgtct
    30301 gactgaaaaa gaacgtaaag aacaaaaaat cgagcagcaa aagcaagaag cagaagaaat
    30361 catgaatcag ccgaaaaaag aacctgacaa aatgaaagta cgtcatgaag gtggcgttgt
    30421 cattcaaggg gtagaaaact tactaattcg tatcagtcgc tgctgtaatc cgattcctgg
    30481 tgatgatatc gttggttata tcactaaagg cagagggata tccattcatc gtcgagattg
    30541 tccgaatgtt cagcctgaca aaccaaatgt agcagaacgt ttgattgaag tcgaatggga
    30601 agatacatcg aatacacgaa aagagtatga tgcagatttg gaaatttacg gctataatcg
    30661 ttcaggctta ttgaatgatg tacttcaaac agtcaatgcg ctaacgaaaa atctcaacag
    30721 cgttgaagca cggacgaata aagataaaat ggcgacgatc catttgacgg ttggtatcca
    30781 gaatttatcc cacctaaaga gtatcgtgga taaaatcaaa gcagtacctg atgtctacag
    30841 tgtacgccgg acgaatggat aggaggacag atatgagagc agttgttcaa cgggtaagta
    30901 aagctgctgt gtcagtcgat cagcaagaaa ttggaaaaat tggctacggc ctacttgttt
    30961 tattaggcat tcatgaaacc gatacgcaaa aagatgtgga ctatctggta aaaaaaattg
    31021 cacaaatgcg tatttttgaa gatgaacaag gaaaaatgaa tattagtgta gaagatgtgg
    31081 gaggacaaat tttaagtatc tctcaattca cactgtttgc ggatacgaaa aaaggaaatc
    31141 gaccaagctt tgtggaagcc gcacgaccag aaacagctat tcctttatac gaatcattca
    31201 atgaaggaat cagaagtcgc ggcatcacag tcgctaccgg acaattcgga gcagatatgt
    31261 cggtttctct cgtcaatgat ggacctgtaa cgatcattat tgattctaaa aacaaataaa
    31321 gtaatctggt tttcactagt aaaaactatg aaacacgtcg cttaagttag actgataaac
    31381 tctaacttaa gtggcttttt tgtctgcaaa aagcgcttct tttgtcagca gtcggaaaaa
    31441 aagttaagct taaattatac aagttatttt ttataggagg ttgctgaaga tgaaagaagt
    31501 accagtagta gatatcaaaa tcacagattt aaaaaaattg tatcaaaaag gatacaacat
    31561 gttggaggag ttacgccatg aagcggacgc tcccgtcgtc aaagcaaaga ttttcaataa
    31621 agaagctatc acgatctacg gatcatcagc agcaaaagta ttttatgatc caaggaattt
    31681 caaacgaaaa ggtgctatgc caaaattagt attgaagaca ctttttggtc aaggtggagt
    31741 acagactttg gatggagctg ctcatcacca tcggaaaaat atttttatgg atctaatgac
    31801 accggaaaga atggaagatt atcatcgtat cttagataag aatctgacac aagcacttga
    31861 agcacagcat ggtcaatttg aactatttga tttaagtaag atggttttct ttacatctat
    31921 ttgcgagtgg gcaggtatca atttatcagc gatttctaaa gatgaggtcg aaaaattagc
    31981 agaatatcaa atctctatga tcagcggaac gtttacttct ccgattgatc acataaaagg
    32041 tgtcgaaaat cgcaaaaaat cagaaaaatg ggcgcaaggc ttgattgaag aagctcgaca
    32101 aaatcctgtg gctggaaaag aaaatgtggc attatatgct tttgccaatg ccacagattt
    32161 agatggtcag cttttacctc tggaagtggc agctgttgaa ttattgaaca tcatccgtcc
    32221 aacggttgct ctaactgtgt gggcggcatt gatgggacat gcacttttca gtagaccaga
    32281 tttgtatcag caattaaaaa atgacttttc gacgttacaa gatccgttta ttcaagaaat
    32341 gagacgctat tatcctttct tcccaatgct acctgcgatt tcgctgaaag aagtagaagt
    32401 agatggttat cgtataccag aaggcagttg ggttatttta gatttatatg gaacagacca
    32461 tgatgaacga acagttgaag cgccagattc ctttatgatc aaacggtatg tagggaaagc
    32521 aaaagatatt tcctataaag aagaatatga gatgattgca caaggcgggg gaaattttcg
    32581 acaaatgcat cgctgtgcag gagaatggat cactcttcat agtctacgtg tgttttccga
    32641 tcagctagta aataagtttg agttctctgt acctgaacaa gattggacga ttccattcaa
    32701 tcagtttccg acttatccga atagccgagc gctactttac aagaattaga ttagcataaa
    32761 cttatcgaaa aaaaggaaga tcaaacagtg ctgatcttcc ttttttcata ttactataaa
    32821 ttgataaggt caattgatca aaatccacga aatgcttcat caatggtttg ataatcttca
    32881 ttggataaat gcaaatctaa agcttggaca ttgtcagata cttgctctgg acgcttagct
    32941 ccaggtataa ctacagacac tcgtggattc ttcatgtacc aagctaaaac aagttgcgca
    33001 ggagtggctt ggtatctttt agcaatgggg cgaagtacat cgacagcggt taaaatttct
    33061 ctgaaacgtt ctccttggaa atctggattt ctttttcgag gatctccttc accaaattgt
    33121 ttttcctcac caagttcata ttttcctgtc agcaaaccgg aagcaagagg aaaataggga
    33181 acaaaactga ttttgttttt ttcaagataa gggaataatt ctttttcagc ctgccgatgg
    33241 atcaaactgt atttatcttc tactacatcg acatatccat ctgcattcgc ttctttcaat
    33301 tgttctaacg tgaagtttga cacaccgact gctcggattt ttcctgcttc ttttaattcg
    33361 tgcaatgtag caactgattc attttttggt gtgctttcat ccggaaagtg gatataaaaa
    33421 atgtcgatgt aatcagtttg cagacgtttt agtgcatctt ccaccgattg tttgagaaac
    33481 tcaggagaat tatcaaatgt tcgcccttta tttggtacat gagcagcttt tgtagcgatg
    33541 acgacacgtg agcgatcata ttctttttcc ttcagtacct cgccaatcag ttcttcggaa
    33601 cggccgtttc cgtaagcata agcggtatcg atcaaattga tcccgctatt caaagctgta
    33661 cgaactactt gttttcctgt ctcatcttcc aaaccgtcaa aaagattatg tcctccaacg
    33721 gcatttgctc ctaatccaag ctgttctgcg tagacttgtg aatgtccgat tcttatttct
    33781 gccatagctg attcctcctt tttgtctagt ctaaaacaaa ataccaaaaa gctgaactaa
    33841 aacgtttttg tgaggggaaa tagtcagata tctcttgact ttgagactgg tttttagtag
    33901 gttataagta atatcgaatg tcaatgaaag agcgagtaag tttttgaaac tttacaagag
    33961 aggatcatcg aggctgaaaa tgatctaaag tttcattagc ctaaagacac tctggagatg
    34021 gacgagtgaa aagccgtccc gcgtacgagc gttattcgta agaggaaaga gaaatctttc
    34081 aaaattaggt ggtaccgtgt atgaatttca ttcacccttg ttcatgatga acaagggtga
    34141 tttttttatt tacatagcta agaaagggag agaaaactat gagtttccaa agaccaaaag
    34201 gaacaaatga tattttgcca ggcgaatcag aaaaatggca gtttgtcgaa gaaacagcac
    34261 gtttattatt cagagattat cagtataatg aaatgcgtac accgattttt gaacactatg
    34321 aagtgatatc ccgaagtgta ggggatacaa cggatatcgt ttcaaaagag atgtatgatt
    34381 tttatgacaa aggggaacgc catgtgacgc ttcgaccaga aggtacagca ccaatcgttc
    34441 gttcttttgt tgagcataaa ttgttcggcc cagagtatgc gaaaccgttc aaaacttttt
    34501 atatgggacc aatgtttcgc tacgaacgcc ctcaaaaagg acggttacgt caattccatc
    34561 aaatcggagt agaagcattt ggatcagaaa accctgcaac tgatgtggag agcatggtga
    34621 tggcacttga tttcttcaaa cagttgggga tcacgcaaat ccggctagtc atcaattcat
    34681 taggtgataa agaaacgcgt caagcctatc gtcaagcatt gatcgactat cttttacctt
    34741 ttgaatcaga gctgagtgaa gactctaaac gccgccttca tgaaaatcca ttacgcgtat
    34801 tggacagtaa agacaaacga gatcaaaaat ttgtggcaga agctccatct atcttagatt
    34861 atctaagcga gcctgctcaa aaacattttg ataccgttgt ttccatgctg gatgcattgg
    34921 ctgttcctta tgaaatcgac agtaatatgg ttcgcggact agattattac acacatacga
    34981 tttttgaaat catgagtgac gcaccaaaaa tgggggcaca agcaacgatt tgcgcaggcg
    35041 gacgttatga caatctagtg gaagaactag gtggtccttc aacacctggc ttcggatttg
    35101 caatgggtat cgagcgatta ctcttgacta tggaggcaga ggaagtagtt atccctgcat
    35161 ttaatgagtt ggatgcttac gtggtcgcac tcggagacga aacaaatatc gaagcattga
    35221 aagtggtcca agcgattcga aactttggtt tttcagctga ccgcgacttc atgaaccgta
    35281 aagcaaaagc gcaatttaag acagcagata aagcgaatgc caaattagta ttggtgatcg
    35341 gtgaagatga gcttgctagt caaacgatta atgtcaaagc aatggcaagc cgaaaagaaa
    35401 aaagttttcc attagaagag atatatgaac attttgatga agtctatgat gaaatgactt
    35461 tattcgagta ggaggaaaaa aataaatggc acaaagaacg atctattgcg gattagtttc
    35521 cgaacaacaa ttagaacaaa cagttacatt aaaaggatgg gtacaaaaaa gacgagacct
    35581 tgggggagta atctttatcg acctacgtga tcgtgaagga atcgttcaaa tcgtctttaa
    35641 tcctgaaatc aacaaagaag catgggaaat cgcggataaa tgtcgcagtg aatacgtgat
    35701 cgaagtgact ggggaagtta gaagacgcgg agaaaatgca gtaaatccta aaatggccac
    35761 tggtgaattc gaagtgattg caagtgaaat cgtgattttg aatcaagcaa aaaccccgcc
    35821 atttcaaatt gaagatgatc aagcaatcag tgacgaaata cgtttgaaat atcgttattt
    35881 ggatctgcgt cgtccaaaaa tgactaaaaa catcaaatta agaaatgcga caacaaaagc
    35941 gattcgtcat tatttagatg ataatgactt tctcgatatc gaaacacctt acctagggaa
    36001 atctacacca gaaggcgcaa gagactacct agttccttca cgtgtccatg ctggacattt
    36061 ctatgcgttg ccgcaatctc ctcaattgtt taaacaattg ctgatgaatg ctggattcga
    36121 ccgttattat caaatcgttc gttgtttccg cgatgaagat ttacgtggag accgtcagcc
    36181 tgaatttacg caagtagata ttgaaacaac gttcttaaca gcagaagaaa tccaaactta
    36241 cacagaggga ttgattgcga aggtaatgaa agaagttcgc ggtatcgaag tcacattgcc
    36301 atttcctcgt atgacctatg atgaagcaat ggctcgctac ggcagcgaca aaccggatac
    36361 acgttttgat atggaattga tcgatctaag cgatacagtc aaagaagtag aattcaaagt
    36421 cttccaaatg gctcttgaaa acggcggtgt cgtgaaagca ttgaatgcta aaggcgctgc
    36481 agatcgctac tcacgaaaag acatggatca gttaggtcaa tatgtaggac aattcggagc
    36541 taaggggctt gcatggctga aagtagaaga agacggattg aaaggtccaa ttgctaaatt
    36601 catgggagaa gcaacagaag caatcattaa agcaacagat gcaaaaccag gtgacttgct
    36661 gatgtttggc gcagataaaa gtgaaatcgt cgctgctgca ttaggtgcta tccggacacg
    36721 tttaggaaaa gaattaggac taattgatga atcgaaattc aatttcttat gggtaactga
    36781 ttggccacaa tttgaatttt cagaagaaga aggtcgatat gtctctgctc accatccatt
    36841 cacgatgcca aaagaagaag atatcccgtt attggctgaa gaccctgcaa aagtctatgc
    36901 agaagcttat gatatcgtct tgaacggtta tgaactaggc ggaggttcta tccgtattca
    36961 tactcgtgag cttcaagaaa aagtactaga aactctaggc tttacaaaag aacaaatgga
    37021 agaacaattt ggtttcttgt taacagcttt agattacgga ttccctccac atggcggtat
    37081 tgcattagga ttggaccgtt ttgcaatgtt attagccgga gaagataata ttcgtgaagt
    37141 cattgccttt cctaaaaacg gaaaagcagc agatgtgatg agtgatgcac caagtatggt
    37201 ttcgccttta caattgttcg aattgaatat tgatgtaacg aatatagaag aatagccgat
    37261 aaaaaggtaa aaaggatttg tcgaatacgc ttcttttgac aaccttgatt taattgaaaa
    37321 acactttata atgaagccat aacatataaa gcggggcttt tccatgaaaa aaacattcga
    37381 aaattgggct tatcatgatt acacgaccaa gctttcggta tctatcgttt atgcgttgat
    37441 cgcatcagtc gcattgaatt tcttttatca gccaggacat atttattcaa gtggtattac
    37501 tggtctagct cagattttga cgactttgtc aaaatcactg ataggattcg aagtaccggt
    37561 atcaacaact ttgtatttac tgaatatacc tttgtttgta ttggcgtggt taaaaatcgg
    37621 gaagaagttt acaattttca cttttatcac agtcactttg acctcccttt gtatccatat
    37681 tttaccggaa acagtcctat ctaccgatcc aatcatctgt gcgttgtttg ggggggctgt
    37741 gatgggacta ggtattgggc tagcgttgag aaacggccta tcatcgggcg gtctagatat
    37801 cgtgagtatc acgattcgta aaaaaacagg aaagtcgatt ggttctattt cgatctactt
    37861 caatgcattg atcgtttttg ttgccggaat tctatttggc tggcaatata tgttttacag
    37921 tacgttgtct attttcgtca gtggaaaagt aactgatgtc gtttatacta aacaaaagaa
    37981 gatgcaggta atgatcgtaa cgaaacatcc agaaaaagta gtaaatgaaa tccaaaactg
    38041 tatgcgtaga gggatcacga tcatcaatga agcagaaggt gcttataagc atgataagca
    38101 gacagtattg atgacgatcg ttacacgata cgaactgcct ctacttagag aagcaatgaa
    38161 agcttctgat ccacaagctt ttgtaagtat tgcagaaaac gtccagatac ttggtcgttt
    38221 ctatgaggat ggcatttaga tcgagtttga caaaaattca tgaaatactg ctgtagacag
    38281 acgttcgttt gtctgcagtt tttttctacc atagtagaat cagcaaagaa aaactgcttt
    38341 tttatttgaa attttcttaa agttgaaaaa aagcatgttt atttttttaa atttatggga
    38401 tgatagaaaa aaatagtaga gaaaggacac gattctactt gctattttca cttaataccc
    38461 gtatattacg aatgaaaaaa gtttatgaaa agttggaata ttgaatggaa aaacaaaaaa
    38521 ggttaaaaaa cagccgctac atcactgggt ttgatgggct ccgttcatta gctgtggtgg
    38581 gtgttatctt ctatcacctt ctgccaacta gtatgaaagg cggctatttg ggcgttccga
    38641 tttttttcgt cgtatctggt tatttgatca cggatctgct gcggcaggaa tgggaacaaa
    38701 atggaaaaat caatatttgg caattttatg tcagaagaat gaagagactc tatccggcac
    38761 ttgtttttat gcttgtgaca gcttcggctt atatcacttt gtttcagcga gggctgttaa
    38821 acaatcttcg aggagttgtg gtcagcagct tactgtatgt caacaactgg tggcaaatca
    38881 ataacggttt atcttatttc gatcgatttg ctaatgagtc accgtttacg catatctggt
    38941 ctttagcagt agaaggtcaa aactatttgg tttggccgat cttgtttgta ttgttgatgg
    39001 tatttgttcg taaaagaaaa tggatctttt atactgtgtt aggtacatcc ttcctctccg
    39061 ccatcttgat gatgatcttg tatacaccag gaggcgatcc aacccgtgtt tattacggta
    39121 ccgacactcg tctgttttct atatggttgg gaagtgcgct tgcgtttgtt tggccaagta
    39181 cgcgtttaaa gaaaaacatc ccgaaacaag cgaaaaatat tctgaatatc gctggaggaa
    39241 tctcgctttt ggcactgatt ctttgcttct tctttttaga tgatcattac aatttcatct
    39301 attacggagg aatgctccta gtgagtctgt tatgcgtagt gctagttgca gtgacagcac
    39361 accccggagc aagtttgaat cgatggctga caaatccagt atttacttgg attggcaaac
    39421 gaagctatgg catttatctg tatcagtttc cagttatgat tttttatgaa gcaaaggtga
    39481 ctgatattgc cgatcatgtt ttgttgcata ctttagtgga aatcacattg attctaatca
    39541 tcagtgaact ttcttatcga tatgtggagc gtccgctagc acgttttgat tatggtcgta
    39601 cattccaagt gatgaaagga tggttcagca aaccgatcat cagtaagagc aaaccatggg
    39661 ttgttccagg cacattactt gtagcaattg cactcgttgg tttcgttacg gcaccgaaaa
    39721 acgctgtaac agccgatcaa aaacaactgc aggcaaaaat cgctgaaagt aaaaaattag
    39781 cagaagaaac cagaaacaat tcagaaaaca ccactagttc ggttgaccaa gcgatccttg
    39841 ataagtacga gttgtccaag gcacaaggga ataaggcaca aaaattagaa ctaacggcat
    39901 ttggtgattc agttatgttg gatgctgcaa cggatctaca agaactttat ccaaaagtag
    39961 tggtagatgg agatgtcgga cgacaattat atgccagtgt accgtacatt gaaaaattaa
    40021 aggaacaaga tttgttgaaa gacactgttc tgatcggact aggaacgaat ggctcattct
    40081 cggaagctca gtttgatagt gtgatggatg caatcggtga tcgaaaagta tactgggtca
    40141 atgtccgagt accgacgaag cgctggcaaa atgacgtgaa tgcgatgctt gaacagatga
    40201 cgaaaaaata cgacaatatg acgctgattg attggtacag ctacagtaat gaccatagtg
    40261 actggtttta tgatgatcaa gtccatccaa atcctgaagg gatgacacat tacattcact
    40321 tagtcagcga agccttgcta ggaggaagtt caagtacgaa cagcagtgag acaaacgtga
    40381 cagaatgata gctacaaaaa acttcaggca aaaacatttg tttttgcctg aagttttttt
    40441 atatttaccg tgtttttaac attcatatag attcaggaag caaaacggtt gagtgtgtct
    40501 gtaaataacg ttctttttgt tttcgggtga gttttttgaa tgcagcttct gcttttgttg
    40561 cttcgcttct tgaagaaaat acttctgcat ggatcatctt aacaggtctt cttttttgaa
    40621 gacgagtata tttagcacca gtaccattgt tatgttcctc taatcgtcta gaaagatcgg
    40681 ttgtatatcc accataaaat gtctgatctt tacagaataa tacgtaaaaa taatgttcat
    40741 ttgccataga gcatctcacg aatctctgca gtgtattctc catccatatt gtaagtgatc
    40801 aatggtggag cgactttgaa tccgtctaat ttgccttctt tgattccttc aactaacaaa
    40861 atatttgcct cttttccagg ttttgggtaa acaaattgga tccttttagg tgcaattcga
    40921 tagtcttcca tgacctgaat gatttctaag aaccgatcag gacgatggac catagtaaag
    40981 cgtccatttg tttttagtag cttacttgaa atatcgatca cttcttctaa cgtcgtatga
    41041 atctcatgac gggcgattgc caggtgttta ttagggttcg ttttatttgt tggcagccct
    41101 ttgaaataag gtggattaca gacgactaag tcacaagaat tatgtcgaac gacagataag
    41161 ctgtctttca gatcgatggt gtggacagtc atttgttcat ttaaatggtt aagcgcgata
    41221 ctacgtcttg ccatgtctgc tagacgaggt tgaagttcga tagcgtcgat agccgcctgg
    41281 gttcgtttac ttaaaaaaag tccaactgcg ccatttcctg cacaaaggtc aacaatcttc
    41341 ccttttttag gtacacggga aaagtgagca agcagcacag catctaaaga aaaagaaaac
    41401 actttggaac tttggataat cttgatatct tctgcgtata attggtcgat tcgttcgtct
    41461 tcgtgaagca tggattccct ccaaaatgaa aaaaatagtc gtctgtatta tactattttt
    41521 attaaaaaga accaaggtgg cttgtcaaac ctctattttt tatgcatact atgaccataa
    41581 gaagggaaag gaagagacta tgttttatcg atttatgcgc ggggtagttc gagtactatt
    41641 agccttagtt aatggaaatg cccgctatga gaataaagaa gttttaccgc aagatgagaa
    41701 ttacatacta gttgctcccc atcgtacttg gtgggaccca ttatatctgg cggtagctgc
    41761 agcacccaag gaattcagct ttatggcaaa agaagaactg ttcaaaaatc cagttctgcg
    41821 atttatatta actcgatcca atgcttttcc agttaaaaga gaaaatccag gaccaagcgt
    41881 cattaaaaca cctgtaaaga ttttgaaatc gacaaatttg agtttgatca tgtttcccag
    41941 tgggacaaga catgctacag aacttaaagg cggaatggca ttgatttcca gaatgtctaa
    42001 agcgaaaatc gtgccagctg tatatcaagg tccgttgaca cttggggatc tgttcaagcg
    42061 tcagagagtg acagtgcgtt tcggcgaacc aatcgactta tcagatatca agaaaacgga
    42121 taaagaaggt atggcggaga tcgaacgacg aacacaagca gcttttgaca aattggacaa
    42181 agaagtgaac cctgatttca aatatgaagt caaaaaaaaa taaaatgata agtttatgcg
    42241 tgggcggtct tttgaatcta ctgtcctgtt cagttcagac tttttcaatg aaaacgaggg
    42301 agagacgtca agtctgccct ctttttgcgt tccaatatgt aaaatagaag acaggtgtca
    42361 tgtaatggat caaagtgtta taataattag aaggacattt tttgaggtga ttgaatgcgt
    42421 tttttacata cagccgattg gcatatcgga aaaaaactac aaggttatga cttgattgaa
    42481 gaccagcgtc atgtactatc ttctatacta gatatcgcga aagaagaaaa agtagaggca
    42541 atcgtgattg ccggagactt atatgatagg agtgtcccag ctgttgatgc cgtagaatta
    42601 tacaatgaat tgatggtcga ttggaattta aaggaaaaga tcccgatttt tgctatatca
    42661 ggaaatcacg atagcagtac gagactttca gcgggtacgc catggttcag ttattcgaac
    42721 tattttttgc gaacacagct agcagaagca tttgaaccag tcgagtttaa aaacgtacaa
    42781 tttttctttc ttccttactt tgaaccaatt gcagcgagat tatattttga agatgacaat
    42841 atccgaacga tcaagcaagc ggtagccaag gtgatagata aaatgcagga gctatttgat
    42901 tcagaaaaaa aacaagtatt gattagccat ttttttgtaa tgggaagtgt aaaatctgat
    42961 tcggaaacga aaatcgaagt aggcgggttg gattcgatcc ctggtgaact acttacaccg
    43021 tttgattatg tagcactagg acatttgcat aatcaagctg ctttgagaca ggataatgct
    43081 cgctatagcg gttccccatt gaaattctct ttatctgaga tcaaccaaaa aaaaggcgta
    43141 tggatcgttg acctgacaac aggcctggag ttgaatttta gggagatcga acccctgcat
    43201 gatattgaag aaataacagc gagtttcaaa gaattgctgg atcctgcctt ttatcagtcc
    43261 gtcaatcggg agaattacat ctatatctat ctcactgata gaacgatcat cccgaatatg
    43321 atgaaccagc ttcggcaaat atatcctcgt attttgggga ttgaacgggc aaacggtcga
    43381 gcagaacaaa caaagcgcaa acgaaaagta ctagaaatga aagatcctca aaaattagca
    43441 gaagcatttt ttagtgaaat gacggaagag cagctaactg caaaccaaga aaaatggctc
    43501 ggagaaacgt tgcaagaaat catggaaatg gaatgatcaa gaatgaaacc gaaaaaatta
    43561 caacttaaaa attttggtcc ttttatcaat gagaccgtag atttttcacg tttgacagaa
    43621 gcaccgcttt ttttgatcag cgggaagaca ggagctggca aaacgacgat ttttgatggg
    43681 atcaccttcg cactttttgg tgaaacttcc ggaagacttc gctctggaaa agagatgcgt
    43741 tctttgtttg ctacaccaga cgaagaaaca agcgtgactt tttcttttga acatcagcag
    43801 atgagctatg aaatcgaacg aaaaccagaa caagttttag caaaacgaaa aggaaacgga
    43861 acaaaaaaac aggcagccaa agtaacgttg accatttttg atgggaaagg aaaagaaata
    43921 aaacaaatca caaaacgtac agaagcagat cagttgatca gagaactgat gaatctcgat
    43981 gcgaaacagt tttctcaaat cgttttacta ccccaaggag aattccgtaa ttttttggtt
    44041 tcatcaagca gtgataaaga gactgtttta cgtcatttat tcggtactca atttttccaa
    44101 cagttcaatg agcgattaaa agaaaaagca aaacaacagc aacaaaaatt ggatcattta
    44161 gagcaagagc tgcatcttct gcaaaaaagg tttgttttag tcaaagaaga ggaaccagca
    44221 gcagggtttg aagccgtttt agcccaatgg acaaaccatc aggcaatact cgaaaaacaa
    44281 atcacggaag aaaaagaagc tctaacggaa cttcaggaaa aacaaaagca actagaaaat
    44341 tcctactatc gttttgaaag cttgaaaaaa agttatgaag aaaaaacgat attaataaac
    44401 aagcaaaagg aattagctgc tcaaaaagac gaaatagagg aaaagaaacg atggattggg
    44461 tattatgaat ttacgcaacg attagtcgaa ccaatccagc gcctacaaga aataaaagtt
    44521 gaaaaaatag aactgtcaca aaaaagtagt gagcaaacaa agaaactagc gatgactacg
    44581 cagaattatg aagagtggca aaaaaatgaa gcaaaccgcg tacgccgaca aacaaaaatc
    44641 aaagaagctg ctcaaaaact gcaaaacaaa cagatgatgg tgccaattgt cgaatcctta
    44701 cgtagtaaaa aacaagacgc agaacaatta acaatttcat tggataaaga agaattgaat
    44761 gccgagaagc tgtatcaaaa tctcgctatc tatcaggaaa gaactcgaat tcttcaagaa
    44821 aatttactgg atcaggaaaa actgcaagaa gatcgtcttg cttttggaca gttaaaatat
    44881 ctagatgaaa agcagcaaga aatagaaaaa caaaaagcaa aagacactgg gtcgctcgca
    44941 cagataagag aagaactcaa aaaagcaact gaagaaataa caaaaaatag tcagctattg
    45001 aaagaacaga cagaacaagc agaacagctg aaaagccaat gggcaaagca gcaaattgct
    45061 cgtcttcagc tttttttgcg tccaggggag ccatgtcttg tttgtggatc aacggaacac
    45121 cccatacaac aattaaaaca cgaacagcca aataaggaag atatcttaaa agtagaacaa
    45181 caactggcag aagctgagtc tgctgtagaa agaactcagc aaatcattgc caaaagtgaa
    45241 gcacatgaaa ataatcttca acaacaatta tcagatttag aacaaaaaat catggcaacg
    45301 aatatacaat tggctgaaca agaagaacac ttgcaacagg ctttgaaaaa ggcatttcct
    45361 gagataacag aacaaaaaac aaaaacaact cttgtagtaa tcgaacaatc tttagataga
    45421 cgaaaaagca agatggccaa tgcaagaata gagctggaag aaataagaca acaagcagaa
    45481 aagctcgaac aacaattagc tgtctacaaa cagcagcaga cagaaaaaaa taatcagctc
    45541 cagcaactgc aaggagaaat caaaagttta gaacaacaat tgcaagatac ggatagtaac
    45601 tgtttagaag aggagatacg acgacttgaa aaacagttag aagaagactc gaatcaacta
    45661 gctgttgagc agaaagcagg agtgcaattg ttgcaagatc ttcatacgct tcggacacag
    45721 cttgatcttc aacatgaaca aatagaaaaa atagatgaaa aaatagaaaa ggaacaagaa
    45781 agaatagcta aaaagttaga aagccagtcg tatttttcaa caattgaaga aatctgtgca
    45841 tttgcacaac agcaagcaca atataaagaa aaccaacgta cagttacttc ttatcatgaa
    45901 gagcaattag tgacagctga ccggctgcgt caattagaaa atatccagct aactgagaca
    45961 ttcccagata cagaagagat cagccaacag ttagaagaaa taagacgtat gatcgaaata
    46021 aagcaagaaa agatatacgg tttacaagaa caaaaaatta gtaatcaaaa aatctacgat
    46081 gaatgtcttt cgatttatca cacaagccag acgaaattag atgagcttac gcaattacag
    46141 cagctttcgc aaacattcaa cggagaaaat cctaagaaga ctagtttgga acggtatgtg
    46201 cttcaggttt atcttcaaga agtgttacaa gtagcaaatg atcatctcca acgtttaacg
    46261 aaaaatcgtt atcaatttga gctagcggat accattggca gttatcgagg gaaaaccgga
    46321 ttagaaatca atatctatga tgatcaggca ggtatgtctc gaagtgcgca taccctgtct
    46381 ggcggtgaga gttttattgc agcactttct ttagcattag ctcttgccga tgtgatccag
    46441 acacaagctg gtggtgtagc aatcgatgca ttgtttattg atgaaggatt tgggtcatta
    46501 gatgaagaag ctttggaaat ggcaatggaa gctttagaaa cgatcgaaag tgaaggaaga
    46561 atgatcggca tcattagtca tgtaagagaa ttgaaagaac gagtattaca acaaataaga
    46621 attgatacag aaggtagcgg acaaagcaaa atacgctatc aacttggata aaaagggaga
    46681 ttggtaacta tgaaatggag tattccagaa aaagtcattg cacgtggacg tcaatacttg
    46741 caagaaggcc gagtgttatc ggttgtccct gaccaagaag aaaacgtgtg gcatgcagaa
    46801 gtcttgggca gtgaattgta tatggttgat ttggatggta cagcaaaaga gatagattac
    46861 tgccaatgtc cctattggga ggaacataaa tattgtaagc atacagttgc tgtggaactt
    46921 tatttacggt cgaaaaatct atctcgtatc atgaaaaaag accagccaat gctagaaccg
    46981 gtaaaagcaa caagtgaggg agaaatcatt gcaaaaggtt tttctcgtct aaaaacacaa
    47041 aacaatcctc aagcggtgca acctttgatt attgaatacc aagtagaaac gattgagact
    47101 aatcagtatc acccagagct ttctattttg gcactttact tgcgtatcgg ttcattggca
    47161 tcaccgaaaa aaacatatat cgtaaaaaac atctatgatt ttttacaagc ttacacagaa
    47221 aaagaaactt acactgttaa taaacagtac cagtttcgtc tagataaacg ggcgtttcaa
    47281 aaagaagatc aaaaaatact cacgcatctt gcaggaagtg ctcagacgca tcaattatta
    47341 ggtacgaacg gcttacaagt caaaggaaaa ctagataaaa gatatctgct tctcccagta
    47401 gaacaagccc gcttcctgtt agagcagatg aatcagacta cacgtttgca tctgcagata
    47461 aatgaacaaa acgatcaagg aatacaattt tccgatcaaa acaaaccttt atcattcaaa
    47521 gtggaaaaat ttggagaaga ttatttgctg caagcattga atgattttga ttttttcttt
    47581 atgcattatc agtggggagt tatccaaggg acattttatt ctctgacgaa atatcaacaa
    47641 acggtttatc aaacttggaa acaattgatt cgccgattgg agaaaccaga agtagtgttc
    47701 aagaaaaaag aattaccgtc tttgtttaaa gagattatcc ctctgctgtc agagatcggc
    47761 gacgtagcta ttgcccctgc agtagaagag gaagtagcag atatccccgt cgaatttatt
    47821 ttctttttcc gaaaagcaaa aggaaaaatc caagctcgag tcgatttcgt ctatggcgaa
    47881 gtcatctatt cgactgaccc gaagcatgag gtctcgacag aacaggcttt tcaggtgtta
    47941 cgtgacacag tagaagagaa acgagtactt gatctattca gaatgtatcg ctaccagaaa
    48001 aatgaaactg gttatgaacg tccattgcca agcggggaag aactatatgc ctttttccgc
    48061 acagaactat ctgtcttccg tcagtttggt gaagtcagac ttggaagaaa attgcaagag
    48121 ttgtatttag atgcgcataa acatcaaccg aaaatcgaag taaccgagac cggttcatgg
    48181 ctcgatattc gattcgatgt gacagggata gaggagcaag aaatcgatca tgtcctgcaa
    48241 agcttgctga gaaatgatgc tttttataca ttagaaaatg gtcaggttct ttcttttgat
    48301 tcagaagaat ttcaacaaac aagccaagtg ttgcaacaat tacgggaatc gatacgtaca
    48361 gaagaaggaa cgatccatgt acctaaaaat caaggattga tcattcaaaa tcaattggaa
    48421 aaaagcaatg ctacttttag tgaatcgttc caaacgatgg tacaagatct cattcatcca
    48481 gaaagatacc aggcacagct tcccaaagga ttgaatgcaa cgatgagaga ttatcaaaag
    48541 caaggttttc gatggttgaa gatgttaggt cattatcagt ttggcggtat tttagccgat
    48601 gaaatgggac ttgggaaaac actacagaca attgcctttt tactttcgga aaaagaagaa
    48661 cggaaaagct tctctgcttt gatcgtagcg cctgcgagct taatttacaa ctggcaggca
    48721 gaggtgagaa aattcgcccc ttctttaagt atccaagtaa tcaatgggaa taaaaaagaa
    48781 cgtgaagaat tactggctaa agacacagat atccgagtga cttcttatgc cagcttaaga
    48841 caggatctag ctaattatca gtcgcaaaaa attgattatt tgattcttga tgaggcacaa
    48901 atggtcaaaa atagcagtac gaaaactgca caagcattga gagaattagc tgtacctcag
    48961 cggtttgcac tgagtgggac accaatcgag aataatttag aagaattgtg gtcattgttt
    49021 gcaacgatta tgccaggatt tttcccgact aaaacaaaat tcagggaact tgccgcagaa
    49081 gaaattgcgc aaatgattcg accgtttatt ttacggcgag ataaacaaac tgtgttgaaa
    49141 gacttgccgg aaaaaacaga gatgaatcta tattctgcac ttacagaaga acaaaaaact
    49201 gtttatttag cttacttgcg tcaaatgcgt gaagaaatca catcaatgga ttctgaagca
    49261 ttcaagaaaa accggatcgg gatacttgct ggtctgacaa gactgcgaca aatttgctgc
    49321 gatcctcgtc tgtttattga agattaccaa ggcggttccg gcaagctcga acaagtaaaa
    49381 gatctactgg tagctgccaa agagaacaaa cgaagagttt tgctgttttc tcaatttaca
    49441 gggatgctga ctatcttgca agaagagtta gccgagctag ggatctcgac attttattta
    49501 agaggcagta cgaaaccaca agatcggtta agtatggtag acgcatttaa tgctggcgaa
    49561 aaagatgttt ttctgatttc cttaaaggct gggggaactg gattgaatct cacgggagca
    49621 gatacggtca tcttgtatga cctttggtgg aatcctgcca ttgaagaaca agctgctgga
    49681 cgtgcacatc ggatcggaca aaaaaatgtg gtagaagtgt ggcgtatgat ctctgaagga
    49741 acgattgagg aacgcatgga ttcactccag caagaaaaac gcgaactgtt ccaaaaagtg
    49801 atccaaggta atgaagaaca gttgacgaaa ctgactgaag aagacatccg catgatttta
    49861 agtgtaggag aaatcgagga gtaagagact cgaaaaagcg ttcagtaatg ggtaagaaag
    49921 cctttctaaa gaagcgattg tttatttgat ttaaaaaata gcaaggaggc tgggattcca
    49981 ttttatccca gcttccttgc tatcattttt ttatttctat ttttaaaggt tatacaaaga
    50041 ttgt
//
LOCUS       DADVXM010000011        48956 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.011, whole genome shotgun sequence.
ACCESSION   DADVXM010000011 DADVXM010000000
VERSION     DADVXM010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 48956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.011"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(318..1025)
                     /locus_tag="KB927_000732"
     CDS             complement(318..1025)
                     /locus_tag="KB927_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839668.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENG"
     gene            complement(1090..1926)
                     /locus_tag="KB927_000733"
     CDS             complement(1090..1926)
                     /locus_tag="KB927_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6839669.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(1944..3353)
                     /locus_tag="KB927_000734"
     CDS             complement(1944..3353)
                     /locus_tag="KB927_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6839670.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYRKVIARNGLA"
     gene            complement(3367..5190)
                     /locus_tag="KB927_000735"
     CDS             complement(3367..5190)
                     /locus_tag="KB927_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6839671.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(6033..6359)
                     /locus_tag="KB927_000736"
     CDS             complement(6033..6359)
                     /locus_tag="KB927_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839672.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(6405..6767)
                     /locus_tag="KB927_000737"
     CDS             complement(6405..6767)
                     /locus_tag="KB927_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBB6839673.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(6804..7019)
                     /locus_tag="KB927_000738"
     CDS             complement(6804..7019)
                     /locus_tag="KB927_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6839674.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            7146..7481
                     /locus_tag="KB927_000739"
     CDS             7146..7481
                     /locus_tag="KB927_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6839675.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(7557..9554)
                     /locus_tag="KB927_000740"
     CDS             complement(7557..9554)
                     /locus_tag="KB927_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839676.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(9652..9927)
                     /locus_tag="KB927_000741"
     CDS             complement(9652..9927)
                     /locus_tag="KB927_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6839677.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            10159..10893
                     /locus_tag="KB927_000742"
     CDS             10159..10893
                     /locus_tag="KB927_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6839678.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            10932..12074
                     /locus_tag="KB927_000743"
     CDS             10932..12074
                     /locus_tag="KB927_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6839679.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(12169..13560)
                     /gene="sufB"
                     /locus_tag="KB927_000744"
     CDS             complement(12169..13560)
                     /gene="sufB"
                     /locus_tag="KB927_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBB6839680.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(13565..14035)
                     /locus_tag="KB927_000745"
     CDS             complement(13565..14035)
                     /locus_tag="KB927_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBB6839681.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(14022..15257)
                     /locus_tag="KB927_000746"
     CDS             complement(14022..15257)
                     /locus_tag="KB927_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6839682.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(15254..16540)
                     /gene="sufD"
                     /locus_tag="KB927_000747"
     CDS             complement(15254..16540)
                     /gene="sufD"
                     /locus_tag="KB927_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBB6839683.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(16553..17326)
                     /gene="sufC"
                     /locus_tag="KB927_000748"
     CDS             complement(16553..17326)
                     /gene="sufC"
                     /locus_tag="KB927_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBB6839684.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(17523..18371)
                     /locus_tag="KB927_000749"
     CDS             complement(17523..18371)
                     /locus_tag="KB927_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBB6839685.1"
                     /translation="MKKKIFGLAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(18395..19081)
                     /locus_tag="KB927_000750"
     CDS             complement(18395..19081)
                     /locus_tag="KB927_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6839686.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(19074..20108)
                     /locus_tag="KB927_000751"
     CDS             complement(19074..20108)
                     /locus_tag="KB927_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6839687.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(20171..20427)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(20503..20841)
                     /locus_tag="KB927_000752"
     CDS             complement(20503..20841)
                     /locus_tag="KB927_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBB6839688.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(20843..21199)
                     /locus_tag="KB927_000753"
     CDS             complement(20843..21199)
                     /locus_tag="KB927_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBB6839689.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(21205..22392)
                     /locus_tag="KB927_000754"
     CDS             complement(21205..22392)
                     /locus_tag="KB927_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6839690.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYFYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVVGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(22583..23428)
                     /locus_tag="KB927_000755"
     CDS             complement(22583..23428)
                     /locus_tag="KB927_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6839691.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YPLPQLMKHLIKRFPKVHFEIEIANSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            23662..24627
                     /locus_tag="KB927_000756"
     CDS             23662..24627
                     /locus_tag="KB927_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBB6839692.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            25127..26170
                     /locus_tag="KB927_000757"
     CDS             25127..26170
                     /locus_tag="KB927_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBB6839693.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     RATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGIKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(26232..26696)
                     /locus_tag="KB927_000758"
     CDS             complement(26232..26696)
                     /locus_tag="KB927_000758"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBB6839694.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQQILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            26941..27888
                     /locus_tag="KB927_000759"
     CDS             26941..27888
                     /locus_tag="KB927_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6839695.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDVDSVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(28099..30171)
                     /locus_tag="KB927_000760"
     CDS             complement(28099..30171)
                     /locus_tag="KB927_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6839696.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEEQKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKEMRINPDF
                     TIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKMLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(30104..30481)
                     /locus_tag="KB927_000761"
     CDS             complement(30104..30481)
                     /locus_tag="KB927_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBB6839697.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEAEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESGKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(30610..31188)
                     /locus_tag="KB927_000762"
     CDS             complement(30610..31188)
                     /locus_tag="KB927_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6839698.1"
                     /translation="MRGNMKMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLEGIHETNQIILQIFEAFQLTKEEKVHRSRELCSMIHGYL
                     SLRFLGYFTKESTIDPEDSYFWMINDFIATLP"
     gene            31320..32612
                     /locus_tag="KB927_000763"
     CDS             31320..32612
                     /locus_tag="KB927_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6839699.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLAHQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNAAALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLMGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSISSGHSPSHRQ"
     gene            complement(32672..33790)
                     /locus_tag="KB927_000764"
     CDS             complement(32672..33790)
                     /locus_tag="KB927_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBB6839700.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SEFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILER
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(33804..35225)
                     /gene="arcD"
                     /locus_tag="KB927_000765"
     CDS             complement(33804..35225)
                     /gene="arcD"
                     /locus_tag="KB927_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBB6839701.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFAIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVAFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(35471..36592)
                     /gene="mnmA"
                     /locus_tag="KB927_000766"
     CDS             complement(35471..36592)
                     /gene="mnmA"
                     /locus_tag="KB927_000766"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBB6839702.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNHAEVVFD
                     EPVRAITPGQAVVFYDEMECLGGGLIDHAYQETKVLQYV"
     gene            36996..37595
                     /locus_tag="KB927_000767"
     CDS             36996..37595
                     /locus_tag="KB927_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6839703.1"
                     /translation="MNYFTSDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(37748..39018)
                     /gene="efmA"
                     /locus_tag="KB927_000768"
                     /pseudo
     CDS             complement(37748..39018)
                     /gene="efmA"
                     /locus_tag="KB927_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
     gene            complement(39289..39633)
                     /locus_tag="KB927_000769"
     CDS             complement(39289..39633)
                     /locus_tag="KB927_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBB6839704.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(39770..40915)
                     /locus_tag="KB927_000770"
     CDS             complement(39770..40915)
                     /locus_tag="KB927_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6839705.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSCQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLEQLVRAVKK"
     gene            complement(41095..42069)
                     /locus_tag="KB927_000771"
     CDS             complement(41095..42069)
                     /locus_tag="KB927_000771"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBB6839706.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(42149..43024)
                     /locus_tag="KB927_000772"
     CDS             complement(42149..43024)
                     /locus_tag="KB927_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBB6839707.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     ALIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKEWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            43154..45061
                     /locus_tag="KB927_000773"
     CDS             43154..45061
                     /locus_tag="KB927_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBB6839708.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNEQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(45602..48880)
                     /locus_tag="KB927_000774"
     CDS             complement(45602..48880)
                     /locus_tag="KB927_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBB6839709.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEGNAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
BASE COUNT        14041 a        10309 c         8645 g        15961 t
ORIGIN      
        1 taaaatatac aaatttctta aaaatttttt cactaaaatc actacctgaa acagtctaaa
       61 acacttatat atcaacgttt aatgaaacta tctccgtttc atttcagata caaataaata
      121 tagtcgggct ccaaatccga aaaaaaatac ccccagtagc ttatcctaag ctactggaga
      181 tgtataagta cggtcatata acaacggggt agggtaaata aatgaaaaag atggaagaat
      241 cattattcaa taactttttt aaatacttcg ttgtaatcag ttacctgtcc gttcttaaat
      301 accacagaat aatcttttta cccattttca agtaaccgaa gtggaatgtc tttaccaact
      361 tgctctgtca ctgcattact gatacctgtt agattagcta ataaatctga taaagattga
      421 gcatctgtag aaatctctgt atcagtattt atcgtgattc ctttatcttc atttacaagc
      481 ttccaagtag gtggtatagc tgtgtatgtt tcgatgaatg aatcaattct ttcatctatc
      541 gtcttcccag tatctacttc tgtctcatta ctcttagatg aatcgattct ttcatccatc
      601 gtctgctccg taactgcttc tgtctcatta ttctcaccgg aaactctctt cacacccaaa
      661 cttatatatt gtccatcttt agtgtgcata gttaaaattc ccacgctttt actaataaat
      721 tcactataac cagttctttc aatagagact tcaatgtatt tcacactatc atactcaaaa
      781 gaaaaataga catgtaaaag cattttgttg tttacatcta cataataatc ctttgactct
      841 acttgagacc ttcctatacg gaatacagct ttactgtctg atatctctat accagcatcc
      901 ttattattaa tctgccaatc tccaagtagc tcttctggca agctagtagt ttcttgtgaa
      961 cactttacca cttcactggt agaggtcgaa acattcacct ccgcactgtt agaagaattt
     1021 tccaaggaat caggagcctt agcacaacca acaagtcttt atatattgtg cagccgatat
     1081 tttcttcatt cagtacaccc ttgaaatatg cagtgttaga taaagcagtt cgtcctgatt
     1141 tgctgaggca cccatctctt cttgaacgta ctccttgatt ttcaaggccg cccgatactc
     1201 tttcggaaaa cgctgcttca ctgaagccag caaaaaatca tccttctccg gcaactcttc
     1261 cttcttaatc attcgggcaa taaaaaactg taaatgcgtc acaaatctta agtaaagcat
     1321 cgaatcttta tcaacctttt tttcgggaaa cagatatcct agcatagcca agatatcctt
     1381 tagtgctctt accgagagca tggtttcttc catatttgct tgttcacttt gggcatttac
     1441 aatgtgaaac gcaatgtttc cagcctcctc ttctggcaac tgaacattca tttttttgtt
     1501 gatcaattgg atagcatagc agccgatctc aaattctttt gggtaatact tttgaatttc
     1561 aatcagcagg cgattttgaa aaacaatgcc tttttgactg cgttcaatgg catgcttcaa
     1621 gtgatcaacc aaggtaaaaa atagactttt attcagctta aagtcaaact tggcgttggc
     1681 ataatcgata attcgcttga cgcaaataat tagatcatcc ggagcagcct caaacagttt
     1741 aatgtaatcc ttttttagag catcagaaag tgaatctaat ttaaatactt tttggatttt
     1801 gtcagccgga accaaatcgc ctttctttag ttgaaatcca atccctttcc ccatcaaaat
     1861 tacttctttg ccttgcttat ctaagcaaag aattaaactg ttgtttaacg ttttaattac
     1921 tctcattaga ttcaccgttc tctctaagct aagccatttc ttgcgattac ttttcgatac
     1981 caaaagaagc tttctttttt tattcgtttt aattctttaa gattctcatc ggttcggtca
     2041 acatatataa aaccataacg cttattgaag ccttgatggg tactaacaac atcaatcgct
     2101 gaccaaggta aataaccaaa aacatctaca ccatctgtta aagctgcttg aatagccaga
     2161 atatgtttgg ctagataatc aattcgatcc tggtcattaa ttcgtctatc ttcctcaact
     2221 atgtcgggtg ccccatagcc attttcagta attaaaatag gtaaatcata gcgatcgtac
     2281 aatttcctca atgttaatcg tagtccagta gggtcaacta cccagccata tggcgtttta
     2341 tctacataag gattttcagc tgcccggtag acaccttctt ctcccaacat gatctgttga
     2401 tcccccgctc tagcggaaac atctgatccg tcatttttgc tggcagcgat ggtggcagtt
     2461 gaataataat taatcgcaat aaaatcgggt ttaccggagg ataaaattgc ctgatcctct
     2521 gcctcaattt taggatataa tccacgatca ttcaaatagt tttcaaacaa ataattgtat
     2581 tttccccgaa ctgctacatc taagaaagac cagcctctca atgtttccca attatgggct
     2641 gcaattgcat cttctggact ggaggtagct tgatacatag ccgttaaatt gattgctgga
     2701 ccgatttttc ctttaagatt caactgatga tacaagtgaa ttactctagc ttgagctaat
     2761 aaaacatggt gattaatttg aaagagttct ttttttgaag gcagctctcc acttggtggc
     2821 aaaccaatcg ctccaggatg aaggatcatc gtgttttgct cattaattgt cagccaatag
     2881 ttcaccttgt caccatactc agtaagcaat acctgtacat agtccacaaa ataatcgata
     2941 gttgctcgat ttaaccaacc gccctgctcc tctagaaaat aaggtaaatc gaaatggtac
     3001 atggtgacaa tcggttcgat tccctgattc aggcattcat caattacttg atgataaaaa
     3061 gaaattccct tttgattggt tttattattt tcaatatcca taattcgcgt ccaagcgatg
     3121 gaaaagcgaa aagcttttaa gcctaattct ttaaacagct gtatatcttc tttatagtga
     3181 tggtaaaaat ccgaggcaac ttcaaaatta gctacccctt ctgtatgctg atacttgtca
     3241 ataatagacg gttgtttccc atcctcctga taggcaccct ctgcctggta ggcactaatg
     3301 gaggcacccc ataaaaactt ctctggaaat gctgaaagct gtttgtattg cacaaaaatc
     3361 ctctccttaa ctaatttgca tcaatggttc gtgttccttt aagcttccgc ttgcttcact
     3421 aattcctgcg taattttcac tgttggtcac taccacaatc actgtatcat cgtagccagc
     3481 gtttctaatg gcagcgaaat cggcgttgat taataattgt cctgctgaca cctgatctcc
     3541 tgcttttaca aatacttcaa agggttcccc ttttaaattc acggtgtcga tccccacatg
     3601 gatcaataat tcaatacctt ctttagaacg tagaccaatc gcatgtttag attctaaaat
     3661 agtaatgact tctccctcaa caggtgaata aatgctgttt tcttctggat gaatggctac
     3721 gccctttccc aatagtccct tagaaaagac agcatcgttc acttcagaaa taggacacac
     3781 ggttcctttt accggatttt caacaatgac tgcttcggct attgccgttt gctctgattc
     3841 atcagaagta tcgtcaaatc caattagata agcaatgata aaggttgcaa caaaggcgat
     3901 tacacacgta ataattgcgt gaacaatatt cattggattt tctccaataa aggctggtaa
     3961 ggctgctaag ccaggggaaa caaaggcata tctgactaaa ccgctcaagc cagcatacaa
     4021 accagcaatt gcaccaccaa tcatggaagc aactaatggt tttttcagct tcaaggttac
     4081 tccatagagt gaaggctcag taattcccat taaagcagtg atcccagtgg acacagctag
     4141 ctgcttcaac tctttgtttt tagttttcgc ggctacagca aaggtagcac ctgattgagc
     4201 aatattagaa gccagcattc ctggcccatt gatcatttca gaacccgtac tgctcaattg
     4261 catagtagcg attggcgtca ttgcccaagc tgtacccgta accaccaaaa atggctgcaa
     4321 accacccatc aaaaatggaa ttaaccaagc tgctttgccg ttaatccatt cagcccccat
     4381 tgctataaga tcgttcagca acgttccaaa cggtccaatg acaaccaacg ctaaaggccc
     4441 cataattaaa aataccagca tcggcttagt aaagaattta ataaacgaag gcgaaattcg
     4501 atccgcaaag ggctctacat aggacatgat ccaaacagta aagataatcg gtaaaactga
     4561 tcccgcataa tctgcagcta ataccggaat tcctagaaaa gaaacggcat cgccagtaga
     4621 aaaaagctgt gaaatatttg gatgaagcaa aatgccagca acagtaatcg ccaaaattgg
     4681 gttgacatca aactttatgg ctgccccata ggctaatagt actggcataa aataaaaggc
     4741 tgcatcagca atagtattca aaatgatgta agtttgacta ctgtctgata gtacaccagt
     4801 caaagtcaag acggccaaaa tggcttttac catcccggca cctgttatag ctggaatcat
     4861 cggtgtaaag gtggtagaaa tgacactaat caatcttgaa ataatacttt cttgattgtc
     4921 tgaagagggg ccctttttaa ttgaagttcc cacttccttt tgaatttcct tgaaggctgt
     4981 ttggacttca ttgccaatca ccacttggta ttgtccaccg ctatccacca cactaattac
     5041 accaagtgtt ttttctaagg ctttcgtatc ggctttcctt ttatctttga gttcaaaacg
     5101 cagtctggtg gcacaatggg ttaagctgac cacattttct tttcccccaa cctgttgcaa
     5161 tacatttctt cctacttctc tgtaatccat tattctctct ccttaaagca gtaaaaaaga
     5221 ccaagtcaaa ccacgcccca atcaacattg aagtgttagt ttgtcttggt cttgcctgca
     5281 taatcagtaa catgccaata acgttatttt gctgtaatcc aataatagca cattatgata
     5341 gcgcaatcaa cagggaattt aattttttat cttttcgttt gaccgtatag ggtaatataa
     5401 cagttagatc acatcaacta gggtatatct gcgtatactt actgctaaaa taagtatatc
     5461 taatattaac tataccagta aaaccattcc tacataacca gcgggaaatt cccaaaatcg
     5521 tgaaagcatc aaaaatgcat ataacggatc acacaacttc aacaattctg ctcttgggaa
     5581 aaattgatga atttggtgag taaaggatgg aataaacagc attccaacaa tataggcaac
     5641 aatagtgata cttgtttttt tggtaaaaat cagtaagcaa tagccaattt caatcattcc
     5701 gagatataaa ggtatcaata gaatgatttg ggctagtatt cttaaaaatt aactagcaaa
     5761 tgtttaaact gatttatttc taatctacat gtagtaagta tttcaattcc accaattatc
     5821 aataaaaata ccaaacatat ccataataat tttttctttt tcatttcttt tatattgtta
     5881 taacagtgaa taacataaaa attcccgaca atcattgtaa tatttttttg tcacctgtat
     5941 tagtatttaa tttataggaa actataaaaa ctccctagtg aatttacacc tttgggagtt
     6001 cctgtttgga cggtatgcat aatacattta aatcaattta acattaacac ctcagcatat
     6061 ggtatctcca catatatacg gtctttcttt ggatagtact caatatttat gttgatagca
     6121 cttccattgt ctaatatagc tttagcccgg tatgtgttat ctccattttc atgagtaatc
     6181 gtcacatcat cacatgatcg atttaagttg tactgttctt gtaaaatctg tgttaccaat
     6241 ggttttgatg acttctctaa tccagatgta cctgtcattt ttgaaaaaat aatacctata
     6301 atagccaaga caacaatacc tataatgaca aacttcttgt tcatatttac tttattcaac
     6361 tttttatctc ctatctccaa aataatttgt tcttatccct cttatcagta cattgacatc
     6421 cctaaaagta caccaaagat tgctccagct acccctgcta tcatcaaaat cgtacccatt
     6481 ttctcatctt tttctcgata taagtagccc ataataacag caacagcacc aaatacaaca
     6541 ggaataaatg ctaacgatac taccatagaa atccaaccaa taatcaaata cagcttccct
     6601 gtctcttgtc catgtacgat ttgttccttc atttcattaa ttgtctgctc agtacttttc
     6661 tttactgtgt ctgttccggt tgtctcatct gtttcttgta gtgctccaca aaactggcaa
     6721 tacttacttt catctgttat ttctttgcca cattttctac aatacatgtc ttctcctcct
     6781 aaaatcattc aattgcttat tagttaactg tttactttat taaatacatc agaaaacagc
     6841 tcattcattg gtacacttaa tatctcagaa agcatcttca tttgataggg tttaggaatc
     6901 gttctccctg tttgccacga acttacacat tgctgtgtaa cattcatttt ttttgctaac
     6961 tccgtttgag aaagtccttt ttcttttctg tatcggctga gattacttac ttttttcatg
     7021 attctcccct cctgttttat tatatacaac aatatgatgt atttcaactc ataaaatata
     7081 aaaaacttca aataccatta caaatacaac aacttgttgt actatactga gatgggggtg
     7141 tattaatgaa acagaaacaa tatgcaaagg tcattagaga aaagcgaaaa gctctcgggt
     7201 ggacacaaaa agaattagct gaaaaaatct tctctacaca acaggcagta gcaagatggg
     7261 aaaattctgt aacagagcct aacctcgata gcttaacagc tctttctaga gccctaggaa
     7321 cccctgtaag ccattttcta gacaatgttg tcgtagatta tgaggaagag tttttggctc
     7381 tctatcgttc tcttagcact gaagatgcag ttcgaacaat tgactatatg aagctattaa
     7441 aaaggcaaga aaatgaacgc aatcagctat tgaaagattg aaaaataaat aacccaccga
     7501 actttaacgg tgggtgtatt gagatgaaat aagattaaga gctatggata acctgtctag
     7561 tttaatacaa ttgggtcttt tctcttcctt actctccgtc catcatctct tgttacactt
     7621 gtaaattgat acagaggaac tatcccagct cctgataata tcaattcttt tattgtttca
     7681 tctatccctg cccctttcgc taaatatatt aaaaaactac tacttgcttt cacattgtat
     7741 agtttcttaa tatccttaga agctcgttca agagtgaatc cttgtttaac aaagtagcct
     7801 ctgtttttta ttaaagcatt tttcacgctg ttatccccaa cattacgtag gcgttcacaa
     7861 acagtgttaa taagttcttt ctctgtcatt agatatgtcc cttgccacga taagccctgt
     7921 aaaacttcat gtgcttcatc taaaatcaat tgtttttcct tgctgagttc tgatcgggaa
     7981 ttttgaggaa atactctttt agcctctttt tcgttaaaac atatcttaac ccattcataa
     8041 gaaaaatatt gatatgtaaa atgaattttt tccagaagtg gaaggatatc ttcattcaat
     8101 ttttgaatca cagaagttgc attaaaaacg tctaatcgat agacattgct tctcttatga
     8161 ttaaagtttc ctaacgcttt ctcttccttt aacctattta ggtattcgag catcttcaaa
     8221 ggaacatctt catcatctaa tttttttatc aatcctataa aagtcataag tgatagtaac
     8281 ttattacatt tatctatgtc ataagtttta ccatagtaag aactcatttt tttagctaat
     8341 tgttcccccg acaaaataca agtcacactt tccttactat catcaaaaaa attaacatca
     8401 gaaagcaaga catcatagac acgtcgcatt tcctctagat aattccttat tgtcctgaaa
     8461 agtttgtctt tcattgattc aagagtgtca aaaagtactt ttgattcctc tttcaatttt
     8521 cgaaaatgtg taggatacaa gtctaggttc tctaatagcc aattaaatgt ttctacccga
     8581 ctgtctttct ttaaaattag catcacaact ccaataaaat tttcactgat atcacaatta
     8641 ctggaatgac aataaaaaat ggaatgccca gttttactgg taaaaatact agcagaggga
     8701 ttatgatcgt tgtgaaacag acatcttaag tttttacttg acttaagtaa tttattcata
     8761 tcaatggtta acaatctttc ataaatctca ttaaaagaca tgtcggagga atcaaacagg
     8821 cagtctttaa accactgttt catttcttct ttgtcgtcat tttttatcaa cttaacaaaa
     8881 tcggtttcat tgactagttc atactctctc cctgaatcac tttgacaatt tttagaacat
     8941 gtcatggtaa aatcaatcgg aagctcagta atatctaaca tgttgtcttc attaattatt
     9001 atcactgcat ctgacttata tcctccaaaa aacattctat tcgaagcatt tacattgtca
     9061 tcacacccgg ggatgttctt tttcaagtat tcgtaaacag caaccatttt accatagtca
     9121 gtaattgctt cttttaatag aaagacaatc ttgtattttt ctagattttc agagtaccga
     9181 atactttttt gtatcgcaaa cgcagaatta tgaactaaat tgatagataa aaccttttct
     9241 atgcttaagt atctactatc atctttactc aaatctacta ccttcccctt ctcatcttta
     9301 acagtgttat cgacatccag aataattact ctggtttcca caaaactctc cttgtcattg
     9361 cctttattct ttgtcttgct tggaataaat gattgtgatg aatttagtat ctctacaaac
     9421 tcatctcttg taacttctct atagttatct aaacacctat ctcttacatc agttttttct
     9481 ttttttgtaa ctggcttctc taataatttt tcttgatcta cataaattgg aatattaatc
     9541 attgatgttt ccatttgtgt ttcctcctta taaaattctg ttaaagacta aaacatacag
     9601 ataataaaaa caaactcttt attactatat gttttagtct tatttgttta ctcaaccttt
     9661 ataccgttcc atgaaactat caatatcaga ttttttaaat ctaatgaccg tatcaatttt
     9721 tataacaggt aacccgtatt gagaaacata ttttctaatc gttcctactg atacacctag
     9781 atattcactt gcctgctgat agtccatata ctctagagtg actccagaaa taatgtcttc
     9841 tagcataggc tttagcactg taattatctc tttcacttgt tgttcaactt gtatagaaac
     9901 aatgctatca atgatttgta gagacatatt tccccctcct ttcgtgattg cttgaacaaa
     9961 ttttctaaga attatcttcg tattttttgc tcaaaataaa agtattttgt tattaaccga
    10021 ttaatcaaac aaaaaatgat taccagttca tcgacataca cataatacct cgataaaaaa
    10081 ggggtgtcaa cagctttgta aaatttattt acaacacccc ttttttgagg tatactaatt
    10141 ttaggaggtg tggtcaatat gataaaacgt ccaccaataa attatttaga acgaaaaaag
    10201 atactcggaa caaaaataaa agctataaga aagagtaaaa aattaacaca accagcattt
    10261 ggtcttatga ttaacaacgg tcaattaatt gacaaaaaaa ctatctacga atgggagaag
    10321 ggaacctatt taccaatacc agagcgatta tcccgaattg ctgatttggg aaatatgagt
    10381 atagaggagt tagtttgtgg caatgtagaa gaatatattt tgggaattat tctttataga
    10441 gatagcattg tactagatgg tataacattt ccagataaaa acctgttcca gcatcttcgt
    10501 caacagttcc caccagtaca ctctaattta gatacatggc tggatagata ttccaaatta
    10561 gaaccagaga tgcaagaatt tattgctaac aagacttgta ataaagttaa aaatgaaaaa
    10621 attagtcttt tcaatatctt aaaaatagaa gaattattca tcaatgctat tgtagaagaa
    10681 tttgacaata acattctttt cctcactagc agtatagaag aactactaga aagaatggta
    10741 gatgaatggc tacctattca attgaaagac atgtcttatc ccgaagaagc tgtgagagaa
    10801 attactgata atataaacaa gctagaacaa acgatttcat caattgggaa aaaatacact
    10861 aagaaaaaaa tgaagggagg tgataccatc tagtggtaag tactccttgt aaactaagag
    10921 gagatgattt aatggcaaaa atatcaaagt acaaaaagaa aaacggtcaa gtggcgtgga
    10981 tgtataaagg acacattgcc accgatccac gaactggtga aaaaataaat actacgagaa
    11041 gaggttttag tagcaaacaa gaagctcaaa aagattatga cgagtacaga catcaaatat
    11101 tatacggtgt taaaaagaaa gcacctgata tgacatttga agacctgtat aatgaatgga
    11161 taactcatca gcgtaccagt gttaaagctt caacaatcgc aatctcagta agatacgcaa
    11221 ataatcaaat acttccagca tttggtaagc ttaaactatc gaatatctct gtcccatatt
    11281 gtcaaaaagt ggtagatgaa tggcacagta aatatgaaag ttacgattat atgagaaaac
    11341 agactgcaca aattttacgc tacggggttg caatgcaata tattgacaat aatcctatgg
    11401 aaaaaacact tcttccacga aaaaaagagt atgagaaaaa tcgtaaattt tactcaaaag
    11461 aggagcttaa taatttactg gatgctttta aagattttgg taacatgaaa caatacgcct
    11521 tcttcagatt attggcatac acaggtatga gaaagagtga agtactcgct ttacagtgga
    11581 aagacataga cacgtttaat aaagaactac atgtcaataa aactcttgct gtagatgaat
    11641 ttggtaaagt tataattcaa tctccgaaaa caagagcttc tagacgagtt atctctttag
    11701 atactgagac tctttctatc ctcaacaact ggaaattaca gcaaaaagaa gagtatttaa
    11761 aacttggata caatactagc tctaaagagc aacatgtttt tacaacagtt aaaaacactc
    11821 tatacattcc aaacactgtt aatgattggt taagatatat tttgaaaaaa tataacttgc
    11881 ctcgtattac acctcatggg tttagacata cacatgctag tttattatta gaagcaggag
    11941 aatctgtcaa ggtagttcaa caacgattag ggcatgaaaa tagtaaagtg acattagaca
    12001 tctatgcaca tattacaaat aatgcaccta agaaaacagg tcaagacttt gctgatatga
    12061 tggctcatca gtaaaagagc tggtcaaaat ctggtcattt ctagtataca ggcaaaacaa
    12121 aaaagctaga acccttatat atcaagggtt ctagctccta taacaggttt acccaacact
    12181 gccttccatc tcataactga tcaatcgatt gagttcgact gcatattcca ttggaagttc
    12241 tttggtgaat ggttcaacaa agcccatgac gatcatttca gttgcttcag attcggtcag
    12301 gcctcggctc atcagatagt agagttgttc ttctgagatt tttgagactt tggcttcgtg
    12361 ttctaaagag acttggctgt tgtggatctc attgaatggg atcgtatcgg atttcgacca
    12421 ttcgtccatg atgatcgtgt cacattcgat atgagagatc gaacccgcac tgtttttggc
    12481 aaaggttact tgtcctcgat agtttacttc tccgccgtct tttgaaattg atttagagac
    12541 gatagagcta gatgtatttg gtgcattgtg gatcattttt gcacccgtat cttggatttg
    12601 gtttgctcct gcaaaggcga tggagagcat ggtgcctcgt gcaccttttc catctaagta
    12661 aacacttggg tatttcatcg ttgtttttgc acctaggttt ccgtcgatcc attcaacggt
    12721 tgcgccttcg tatgcttttg ctcgtttggt tactaagttg tacacattgt ctgaccagtt
    12781 ttggatcgtt gtgtaacggc aatacgcatc ttttcttgta aagatttcta cgatggcggc
    12841 atgcaggctg ttacttgaat aagtaggtgc cgtacaacct tcgacatagt ggatgcttgc
    12901 tccttcgtca acaatgatca gcgtacgttc gaattgcccc gtgttttccg cattgatccg
    12961 gaagtacgtt tgtaatggaa catcgacttt gacgcctttt ggcacgtaaa taaaggtccc
    13021 acctgaccat acggctgaat tcagcgctgc taatttgttg tcggttggcg gtacaagttt
    13081 tgaaaagtac tctttgaata attcagggta ttctttcaaa gcagagtcag tgtcagtaaa
    13141 gacgattcct aacttttcga attcatcttt catattatgg tacacgactt ctgattcata
    13201 ttgtgcggaa gcaccggcta gataagctcg ttcagcttct ggtataccaa tcttttcaaa
    13261 tgtatctttg attttttctg gtacgtcttc ccagtcacga gcgggtttgt cacttggttt
    13321 ttggtaatat ttgatggcat cgaaatcgat gtctgaaagg tcggggcccc atgtttgcat
    13381 tggcattttg ttaaatgttt ctagagattt cagacggaat tcaagcatcc attctggttc
    13441 gcctttgatt cttgacatct cacggatcac ttcttctgtc aagccttctc ctgtactgaa
    13501 aaccggttcg acatcatcgt gaaacccgaa tttatattct tctaattctg gtacgcccat
    13561 gttctcactc ctcttccttg tggtaatgat ggaaagctgc ggtaccatcg ttttccattg
    13621 cttttcctag tgctttccag gcaagtgtcg cacatttgat ccgagcggga aatttagcta
    13681 caccaccaag catagcagca tcgcctaatt ggtcgggatc tttgacttct tttccttgga
    13741 caagctgtag aaagtctaca gttaaatgtt ctgcttcttc tattgatttt ccgatgacgg
    13801 cgtctgtcat catcgaggca cttgccgtac tgatggagca gccactgccg tcaaaggcga
    13861 tatttttgat gattccgtct tttacatcga cttgcaattc gatcacatct ccacatgtgg
    13921 ggttgttcaa ttcgatcttg cttgtcgagt cagtcaagct tccacgatga tgcggatggg
    13981 aagaatgatc caagatcact tgacggtata aattgtctaa tttagatagt cccatgttgg
    14041 aaaaactcct ttgttgccat gattgcttca actaaacggt cggcgtcttg cgttgtgttg
    14101 tagaaataaa agctcgcgcg agcagtcgct gatacttcaa ggtacttcaa tagcggttgc
    14161 gcacaatgat gacctgctct gacggctacc ccttccatgt ctaaagctgt cgcgacatca
    14221 tggggatgta acccatccaa attgaatgca acgactcctg tccgaaaatt cgggtcttgt
    14281 ggaccataaa cagtcaatcc atcaattgct tgtaattttg gcaacacata agcggctagt
    14341 tcttcttcat atcgatggat attgtccata ccgagttttt gcaaataatc gattgcatgg
    14401 cctaatgcga tagcgccggc gatatttggt gtccctgctt cgaatttcca aggtagttct
    14461 ttccatgtac tgtcgtataa ttcgacaaaa tcgatcattt cgccaccaaa ttcaacaggt
    14521 tccatttctt ctaaccattt tcgtttacca tataaaacac caatacctgt tggtccgcac
    14581 attttgtgtc cgctgaaagc aaagaaatca cagtctagtg cttggacatc aatggccatg
    14641 tgcggggcag attgagcacc atctactacg atgaccccgc cgttttcatg gacaagttca
    14701 gctaattctt gaacaggatt gaagacacct aagacattgg atacatgagc aatggagacg
    14761 attttggttt tgtccgtaat ctttttcgct gcatcctcca tatccaggaa gccttcttct
    14821 gttagttcga tatatttcaa gacagcacct gttcgttttg ccaactgctg ccacgggata
    14881 acattagaat gatgttccat gtaagagagc actatctcgt ctcctgcttt gatatagcgg
    14941 tcgccgaagg ttctggctac ccaattcaag cttgtcgtcg taccacgagt aaacagcact
    15001 tctgctgttt cttttgcatg gatgaacgcc cgtacttttt ctcttgcttg ttcataatca
    15061 tgggtcgcgc gttctgctaa cgtatggaca ccgcgatgaa cattggcgtt atcgtgttcg
    15121 taatagtacg ctaatgcctg gagtacttgt tttggctttt gggtcgtcgc tgcattatcc
    15181 agataaacta aaggttcatc attgacgtct tgaaataaga taggaaaatc attgcgtagc
    15241 tttttagcat cgatcatcca ttcaacttcc cttcgattac ttcgactaat tctttccgaa
    15301 cttgttctac agggattgct gttaagacag aaccgaggaa tcctcgaatc actaagcgct
    15361 ctgcttcttc tttatgcaat cctctactca tcagatagta catttcttct ggatcaactc
    15421 gtcctacact ggcagcatgt ccagcagtta cttcgttttc atcgatcaaa agaataggat
    15481 tcgcatcacc acgtgcttta tcagaaagca tcaagacacg actttcttgt tgggcatctg
    15541 caccttttgc ccctttcaag atgtggccga taccattaaa ggtcaatgtt cctttttctc
    15601 ggatcactcc gtgttgcaaa atatgcccga tcgtatgagg ggctttattg gttactcgtg
    15661 tatcgattcc ttggatttgt ctgcccgagc tgattgccac gattttgact tctgcgtgtg
    15721 caccttctcc tgctaaatct gagtcaaagt cagcgatcac atgaccgtca ttcatgacac
    15781 caattgccca gtcgacagaa gcatctcgta aaatgtgccc acggcgattc atataagaag
    15841 taatattttc tcctaattga tctacggctg aatatttgat ttttgaacca gctttagcga
    15901 tgacttccac gatgatatta cctgatgatt ttgctacttg ttctttggtt gtctggaaac
    15961 gttccagata agaaaattca ctatgttcat ctgccacgat caacacatgc ttgaagaagt
    16021 gctcatcgga tgcgccatct tgaatgaata aggactcgag tggttcatcg atcacgacat
    16081 ttttaggcac atacaggaaa ataccgctgt tcataaaagc tacatggagt gcagtcaatt
    16141 ggtcttcgtt catgtttact gcttttttca tataatattc ttggactagt tctggatatt
    16201 cgatcattgc agtgaacaag tcggtaaaaa tgactccttt ttctgctaat tccacaggca
    16261 gttgttcaaa aatcgtccat gaaccttgtt ggacaagcac aggattgtct ttcattgcat
    16321 caaatgccgg aatcgtgcct gtttcactga tggtttgtgt ttctttcaca tcaaataacg
    16381 accagcgatg gaatttcacc cgatcgatat gcggcaatgg cagttcatct gctttcgcta
    16441 gtgcgtcttg acggaaggtt ctcatccaat caggttcgcc tttacttaaa gaaaaatcat
    16501 ttaccgcgtc aagataatcg agccagtttt tttctttcat tcttgctccc ccttacgctt
    16561 cttcttcttt atagtcgatt cctaattctt tactgatacc agcgtagcct tctgcttcca
    16621 gacgtttagc taggtcagca ttccctgtca tgactactcg gccttccatc atgatgtgaa
    16681 cgacatcagg tgtgatatag ttcaataatc gttgatagtg ggtgatgatc aatgcaccga
    16741 aattgtctcc gcgcatttca tttactcctt tagcaacgac tttcaaagca tcgatatcca
    16801 gacctgaatc gatttcgtct aaaattgcaa atgtaggttc taacatcaac aattgcagga
    16861 tctcattccg tttcttttct ccgccagaaa aaccttcgtt cagataacgt tcagccattt
    16921 cttctggcat atttagtaaa gccatttttt catctaactt tttcaaaaat gccataacag
    16981 aaattttgtc gttttcatca cgtttcgcat tgatcgctgc acgcatgaat tccgcattcg
    17041 tgatacctgg tatctcactt ggatattgca tagctaaaaa taagccaagt cgcgcacgtt
    17101 catctacttc caagtctaaa acatttttcc cgtcaaacaa aatttcgcct tctgttactt
    17161 catagtttgg attgcccatg atagcggcag ataaggtaga ttttcctgtg ccgttaggtc
    17221 ccatgatggc atggatttct ccggttttca ttgttaggtt tacgccttta aggatttctt
    17281 tttcctcgat cgacacatgt agatttttta tttctaagac agacatgcat tataccccca
    17341 aattctcttt cgttctcact cattttagac taattgagaa tgaagcgcaa tgaccttcct
    17401 tactaaaatc aaatatcttt tatttattat taaacaattt tgatttctaa attagaatag
    17461 gtataaaaaa gatgagaaat aagccattac agacttattt ctcatctttt ttgttccata
    17521 ccttattttg catcagcctt tactggttta acagagccgc cccatttgtc tgtgatccat
    17581 tcttggactt ctttgcggtg aagcacttca atcagttttt tgattttgtc actgtcttca
    17641 tcacctttac gagtcgcaat aatattcacg taaggagagt tgtccttttc aagcaatacg
    17701 gcatcttcta atggattcaa ccctgcgccg taagcgaagt ttgcgttgat tgcaactagg
    17761 tcaccttcat cattttggta cgtagaagct aaaagtgatg ggtcgatcgt atggttgaac
    17821 ttcaagttct tagggttttc ttcaatatca tcgaatgttg ctgtttccag atctactcca
    17881 tctttgactt tgactaagcc agcatcttgt agaattgtga tgatgcgtcc ccagtctgat
    17941 tcagaatttg aagtaatgat tgttgcacca tcttttaatt cggaaacatc tttgactttt
    18001 ttagagtaca agcccattgg ttcgatgtgg acagcaccgg cattgacaaa gtcatatcct
    18061 ttttctttga tttctttgtt caaataagga atatgctgga agtaattggc atcaatgtcg
    18121 ccttcttcca aagattggtt cggtaataca tagtcatcga atttgacgat ttcaagatcg
    18181 attccttcat ctttcaataa tggtttcaca tgttccaaaa tctctgcgtg cggtgtcggt
    18241 gaagcgccga ctttcaatgt cgtgtcgtct gctttatttg ctgaatcttt gctgtcgctg
    18301 ttgttaccgc atgctgctaa tcctacagtc agcaaaagcg ctgctgctaa tccaaaaatt
    18361 ttctttttca tatcctacat ccccctatat cctattatct tttgtctgtt ttcttagtta
    18421 agaaatcacc gattccttga acgataaata cgattagtaa aataattaaa gtcgcaacga
    18481 atgtcactgt cagattacca cgctggtagc cttcctgcca agcaagacct ccaagtccac
    18541 ctgcgccgat cgcgccggcc atcgcagtaa atccgatcat cgagatcgtt gtaactgtta
    18601 atccagaaat caatgcggga atactttcag gtatcaagac cttccagatg atttcccagt
    18661 aacttgctcc cattgcatct gctgcttcca gtacaccagg gctgacttca cgaaaagcaa
    18721 tctctactag acgggcataa aatggtgctg cggataaaac aagagctgga atggctgctt
    18781 gcgcacctag catagtgcct acgattgctt tagtaaatgg aatgatcaaa accatcagga
    18841 tcataaatgg cgttgaccgg aaaatattac tgatgatcga tacgattcca taaatgattc
    18901 gagcatacgg tttgtttttg cgtccaatag agtaaaggat caatcccaaa actaatccga
    18961 tgatcgtcac taagaccatt gagattaatg tcatatatag tgtatcaagg atagcctgat
    19021 tcatcgtttc cgggttgatt tgtttaaaat ctagatatgt ttctgaaaag cttttatcca
    19081 cgatggatca cctcaattcc tactccttgt tctttgatga acacttctgc ttgatctaat
    19141 tctttggttt caccagtcat caagacagtc aatgaaccaa aggaaccttc tttcacttgt
    19201 ttgatctttc catacacaac gttgacatcg atgttatagc gtcgaatcgc ttgggaaatg
    19261 actggctcgt tggcatttct ttcgctaaag gtcaaagttg ccaaacggcc gcttggattt
    19321 tctttgatga gttcagctaa tagttctgtc gaatcagctt ctggttcgat gtcttgttgt
    19381 acaaagcgtt tggttacttc ttttttcggt tgtctgaaga cagtcaatac gtctccttct
    19441 tctacgactt tccccaactc catcacagcg actttgttgc agattttgcg gatcacattc
    19501 atttcatgtg tgatcaagac gatggtcaaa ttcaatttct tattgatcgc taacaataag
    19561 tctaatactt cttctgttgt ttgcgggtcc aatgcgctag tagcctcatc acaaagcagg
    19621 atctcaggat catttgccaa tgctcgtgcg ataccgacgc gttgtttctg cccgccggaa
    19681 agttgtgaag gatatgcttg tccgcgtcct tctaacccga ctaaacgcaa cagttcttct
    19741 gcccgttctt tacgtttgct ctttggtacg ccagctaatt ccagcggcag ctggatattt
    19801 tcaagtacag ttcttgacca taacaggttg aaatgctgga agatcatacc gattttcttt
    19861 cggaatgtac gtaattcttt gttttttaat tttgtaatat cttgatcgtt tacgatcact
    19921 tcgccgctcg tgggaagctc aagtccattc aggagacgga ctaatgtact ttttcctgcg
    19981 ccagaatagc cgacgattcc ataaatatcc cctttttcaa cgtttagtga aacgtcattg
    20041 acggcttgga tgtttccgtt tttcccattg aatgtctttt tgacattcgt tagttggatt
    20101 aatgacatgc cattcacatc tttctcttat gatttttcaa acaaaaaagc cttcgccctc
    20161 ttgccttaag caaaaggacg aaagcttgaa cttccgtgtt accaccttga tttaccgtta
    20221 cttcgcaata acagcctctt ccagtacttg gacttagctt ctttccgtat actgtcgcgc
    20281 tgtaacgggc actcccgtag taagtttgct tacgctcgct tactctgctc taagaccatc
    20341 ttccatctca ttttcgttac ccattttcag caaacagggc tctcttcaaa cgtccgtgac
    20401 atgtactctt cttttcaaag ctttctcgtt tcatatagga ttgcttatga ttatagcaac
    20461 tggaagaatc agtgtcaact tttttcaagt gattttctga ttttataatt cgtcaaattc
    20521 ttttggatca acatctttga aacttaagat ccacgcattc atttcatctg aatcattcaa
    20581 gatattgata tcttcaccga ttttatcatt aacagaagaa actgtacccg ttagcgggct
    20641 ggcaaattca ttgaccgctt tttccgcttc aacttcgatc agaggttcat ctttttttag
    20701 cgattgtcct gcttttggca gattggcaaa cgtgatgtct ccaagttctt cttgcgcttc
    20761 atttgtcaaa ccaacacagt attcttttcc attaaataag atccaaaggt tgtccttttt
    20821 cttcaaatgc ttgcctgcca ttttatatca gttctccttc ataaattttt tcattgaatc
    20881 caattgcaac aagctggtcc tctcgtaaga tcagtggccg cttgatcagc ataccatctg
    20941 tcgataagac ttggctcgct tttgaagccg taaactcgcc tacttgatct ttcagtccaa
    21001 gttcccgata tttcatcccg cttgtgttga acaggcgacg gattggtact tgactcgttt
    21061 ctagccaagt ctcaatcgtt gaggccttcg gtacttcttt gatcatatca acagtttgat
    21121 aactaacgcc atgctggtct aaccacgctt tggctttttt gcatgttgaa catttcgggt
    21181 accagtaaaa ggtgtacaat tttcttacct ccttgaagat cttgcaggtg cttcattttg
    21241 gtatctcatc gataatatca acccgatacc gatcatgttc cctaaaatcg aagatcctcc
    21301 ctgactaatg aaaggcaatg ggatccctgt taaaggaagt aatccgatat ttgctccaat
    21361 attctcaaag acatggaaca gcagcatcat gatcaaaccg cttgcgatat aggcgtaaaa
    21421 ttcattattc gtatcgaaac acacccgaat catacgatag attaaaataa aatacaagaa
    21481 aatgacaaat gcaccaccga taaagccgaa gttttcaccg acaacggtaa aaatcatatc
    21541 ggactcacga acaggcacat aaatattgct tacgttgaat cctttaccaa acaagccacc
    21601 ggtaccaatt gccaaaagtc cttgggccgg ctgataactc attcctgacg tatcatggaa
    21661 agggtccagc catgaatcaa tacgtgcaaa ctgataagat ttgaagccaa ctttgtaaag
    21721 caagtctctt ccgccttcag tcgtaaccaa gaagatcgtt cctgctccaa cgactactgc
    21781 caagattact acaggtgcga tgatgcgcca agagattcca gacatcaaga aaatcccgcc
    21841 aaagatcgca agaaagacaa gcatcgttcc aaagtcatct tgggccatga tcaatgctaa
    21901 aaccggtatt gtcacgatca agagcttccc aatcagccaa aagtccgatt tcatcgtccg
    21961 ttcttttact tgcgtattat gtttagttac gatcagtgcc atcatcaaga tgtacgcaat
    22021 cttcatcaac tctgctggct ggaaagtaaa cgcaccgaat cgaaaccagt ttttagaccc
    22081 tgttgaagca gctaaattct gatcatagaa tttgagcaag agtcccatta ccactaaccc
    22141 caaaccataa aagtaaggag tcagtttcca gatccatttg gaattcaaat gcatgatgac
    22201 aacgattgct gccgctccaa ctaaatacca gacaacttgc atccctacgc ctttcaagac
    22261 tgctggattg ttcggatcat ggctaagtgc tacatataat gagagcagac caatcaaaca
    22321 taacagaaag actggtaaaa tcacgccata atcaatacga ttatcgttcg aagcttttaa
    22381 ttttttttcc atgtttcatc ccttttctta aaaaccatac tgctgattat tatagcggtc
    22441 caattagata atggaaagtc tttccataga catttgggaa aaattaactt tccgtttgtg
    22501 cagttgcttg agcaaatgca gtacaaaagc ctactgctta tctttagtgt atcatagaac
    22561 tttttttgat acatgcaatt atctaccaac tgagattctc ctcgctgtga gaagtttctg
    22621 tgctttcatt gtatcgaagg atctcttcgg caatctctag cagctgatca gaaaccagat
    22681 tggttcgttg gatgaaataa aaataacgat ggaaattcaa cggagtcatt ggcacatttt
    22741 ctggaacaga gcgcttagac aaaatcgagc gaccgattcc ttccttcagc aacgcaacaa
    22801 ttacatcgtt acttttcacg atcatcttct tatcttggat attcatctct tcaaaataac
    22861 gctgcgtgta atgaaaaaca ccagagtttg cttctcttac aagccacaat ttgctttttg
    22921 ggtccccagc gatgactagc tggtcttcca tcaaagagta tctttgtacg ccggaagtct
    22981 ctaatggctt ttcgataaaa ccaaaatcgg attcatgttt cgctacttgt tctaatgatt
    23041 catgagaatt cgcgatttcg atctcaaaat gcactttagg aaaccttttg atcagatgtt
    23101 tcatcaactg aggcaaagga tagacagcaa aggtgtggga agcaacgatt cgacatactt
    23161 cttcttcatt ttgttcattg agcaattttt gctgagtttc ttcccattct tctaacaaaa
    23221 ccagtgtccg ttcatataat aagtcggctt gcttagttgg aagcatctct tttcttccgt
    23281 tacgttgaaa aagatcgata ttcaattccc gctccaactg tttgatttga ttcgagactg
    23341 ctggttgaga taaaaacagt acttctgctg ctctggaaaa atttcttgtt tcatatactg
    23401 cccgaaaagt cgttaataac ttaaacatgg caccacttcc ataacttttt atgataatta
    23461 ctataaaaac tatttgattt aaatatacaa aaaaccatct ataatagaaa tgtacaacaa
    23521 aacagttgct gatccaacta gtaacttaga tgaagacaat cagctgtctg cttgctcgta
    23581 atcatacatt cctattcatt ttacaatgta ttcgttcatc ttggtactaa aatctattaa
    23641 ataaaaagga gaatattata tatgaagaac tttttgaaaa ttattccgat cccgatctgc
    23701 gggttgatcc ttgggttagc ttcccttgga aatctgttta aagactatca ccatgttgct
    23761 ttaggcaatc taactggcgg tatctctatg attcttatga tattcatttt tgttaaattg
    23821 tttatcttat tcgaacacac gaaacaaacg ttgcatgatc caatcatcgc ctccgtttca
    23881 ccaactttta cgatgtcact catggttatt tgtacttatt ttgtttcata tgaaagtatt
    23941 gcaccaattg tcaaattcat ttggctgtgc gctgttatct tccaagtgat ccttgtcttt
    24001 tatttcaatt atcaccatgt tatcaaagct gatctttcaa ttgaagcaat ttatccaagc
    24061 tggtttatca tttatgttgg atttggggtc atcactgtaa ctgccgggaa cttcttcccg
    24121 cttattggaa aaattttctt ttggatttca ttgatctgct atgcgttctt attgccgatc
    24181 atcatcaaac gtgtcttttt cgtaagaaat atggctcatc cgacacgtcc gctgattacg
    24241 atcgttgcag cacctggttc tctttgccta acaggttatc ttaaaaactt tgctgaacct
    24301 aatttttatc ttgtcgtagc attgttcgct ttatctcaag tattgtattt cgttgtgctg
    24361 tctatgcttc cacgtttgtt caagcttcgt ttttatccaa gctatgcagc ctttacattc
    24421 ccgcttgtta tctctgcaac agctatattt actactgttc attacttcaa cagtttaggt
    24481 atctatagta gcgtattgga tttcttaaaa gttgcggaat gtctgtttgc aagtgtagtt
    24541 gtcttctacg ttcttgctca ttacgtacgt ttcttaatta aagaacatag caaacatgga
    24601 aaatttgttt ctaaaaaaat cgcttaataa tcgattcaat aggttgtgaa aaagctgttc
    24661 tgcatcaagt aataagaacg gccaaacaaa aacagctgtt catgtttttg aattggttgg
    24721 gcttattacc gcagatgcaa gcttttgaac accgtttacc aagaggtcgt aaaagaagtg
    24781 gccagcttca agaaataaga aggaatttac gaaaattgct tctcaaattt ttgtgaaatt
    24841 tcggcttatt tccgaaaaag ctacttctgg aacaccgttt accaagaggt cgtgaaaaag
    24901 ccgcttagtt tcgagtatta agaaaaattt tgtgaaaatg gctttccaca tttttgcata
    24961 aatttggctt aataccgaga aactggcttt tgaacaccgt ttattcgaaa caagaggtcg
    25021 tgacaagact tttgtcacga cctcttgttc ttttgtcaaa atactggttt agtgctacta
    25081 tgttcgagta tgcttttagt atttattgac gaaaggaacc gatcaaatga aatcattgtc
    25141 acatccaata aaatctgtaa aggattcagc ggtccgcgaa atcttacccg gtttactgct
    25201 ttcttttgcc atcgctgcct tcagcaggct tcttgctatt tatctgccac agttaggtag
    25261 agcgactatt gctattttat tgggtatttt attaggaaat acttttttta aacagcctgt
    25321 tctagcaatc ggcacaaaat ttgctgaaag caaactatta gaattctctg tttttttact
    25381 aggtgcaact gtcacagctc aaacgattgc tcaaattggt ataaaaggaa ttgtttttgt
    25441 gttactgcaa atgtcagtca ctatcatcgg tgcttacttg attggtaaaa aactgcaatt
    25501 cagcgatact tcttctttga tgatggctgg aggaaacgct gtttgtggtt cttctgctat
    25561 tgcttcgatc gccccttcca tccatgcgaa agaggaagaa aaaggacaga tcatcacact
    25621 agtcaatcta ctgggtactg tgatgatgtt gactctccct ttccttggat tacagttgtt
    25681 tggtggaaat ctcattgaaa aaagtgcact tttgggtggc acactccaat ctgttggtca
    25741 agtagtcgct ggggcaagct tacttgacaa ttctgttgtc gaattcgcca tgctatttaa
    25801 gattctacgt attatgatgc tcgttgttgt tgtctatctg tttgaaaaat tcatgcacaa
    25861 gaaacaacca gctctgtttg aaacgccaac tgatacgcag aaaaaacgaa aattaccact
    25921 tccttggtat gtattagggt ttgtgatctt ttgtttggtc aacagcttgt tttctttacc
    25981 tgtagttatt gaccaatcgg cacattttat cagcagctgg tttgagatca ctgctttagc
    26041 ggcaattggt ctgcgtttag actttgcaaa attcatgaaa gaaggtacac gcttcttatc
    26101 ttatggatta gctgtcgggc ttctccaaac agtgatggct ttactattta tttggctgat
    26161 caaagtttag aatgaacatg aaaaaacagt tgtgattctc gcatggaaca atgtccgaat
    26221 cacaactgtt tttaattttg cagatatcct tctaacaaca acaattggcg tttgatttca
    26281 accccatcta ttgcgtttcc catatatcct gtcagttttc cattttgccc gatcactcga
    26341 tgacaaggaa taacgattgg caatggattg gttcgatttg cctgcccaat cgctcgcaca
    26401 gctttcggac tatcaacagc aacagctact tctttatacg ttcggatttc tccataagga
    26461 atggtcgaca aagctttcca gacattttgc tgaaaaggcg tacctctctt tatagataaa
    26521 ggaacatcaa attcttttct ttttcccgca aaatattctt caaactgttc ttgtgtgcgc
    26581 gttaaaattt gctgattcgc tgattcgctt tctgaaattg gctgaaaaga tacagcagtc
    26641 aatccggatt catctgcatc taaccataaa aagccgatag gtgtgtgtat tttcattttg
    26701 tttgctcctg gtcagtagac tggaacttcc tcctttttct ctatccaaaa ctacttgcca
    26761 actaataaaa attgttctta aaagtttgat aaaccgagga aacatggtaa actaaatacg
    26821 ttagtttacc aaagaatagc tgttcttttc cataaaatca aatttaaaag gtgttattta
    26881 aggtttatta aattttgaat gtaaaccata tataaacata cgattgaaag gatagaaacg
    26941 atgaaagtat caattgttgt cccatgtttt aatgaagaaa aaactgttcc tctttttttt
    27001 gatgaggttg aaaaattcaa aggtgcccat gagttcgaat atttgtttat tgacgacgga
    27061 tcaaaagacg gtacgttagc agcaatcaag aagctagcct cagcttatcc ttatgtccgc
    27121 tttgtctcat tttccagaaa ttttgggaaa gaagcggctc tgtacgctgg attgcaagct
    27181 tctacaggag atttagtgac cgtgatggat gttgatctgc aagatccgcc cgaactgctt
    27241 cctgagatga tcaaccggat cactacttct gatgtcgata gtgtcggcac ccggcgttcg
    27301 actcgtgaag gcgagcctgc gatacgcagt ttctttgcga aaaaattcta ccagttgatc
    27361 aataaaatca gcgatacaga aatggtcgat ggcgctcgtg atttccgctt gatgactcgt
    27421 caaatggtgg atgccgtcct agaattaaca gaatacaacc gattttcaaa aggattattt
    27481 agctgggtcg gatttaaaac agaatatatt tcttatgaaa accgcgaacg tgtggctggc
    27541 gaaacatctt ggtccttctg gaaattattc aactactcga ttgatggtat cgtgaacttc
    27601 tcggatgcac cgttaacgat tgcttcattt atcggcgctt tgtcttgtgt cggttctggt
    27661 attgcaattt tgttcattat tttgcgggca ttgttgtttg gtgatcctac atcaggatgg
    27721 ccttccatgg tctcgatctt cctgttcatt ggtggaatcc aattgttatg tcttggaatc
    27781 atcgggaaat atatcgggaa aatcttctta gaaacgaaac agcgtcctgt ttatatcata
    27841 agagaaacag aaaaagtgaa gccaaatgaa ttgaagcctc accaataata tacgtcaaat
    27901 gaagtaaaca tttttttaaa tgaaaaagga ctgtgacaaa agtcttgtca cagtcctttt
    27961 ttccgaataa atggtgttcc agaagtagct tcttcggaaa taagccgaaa tttcacaaaa
    28021 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctatcac
    28081 aacctctttc atatcttatt acttcttcat tgctgctttt agtgctgctg ctaatgggct
    28141 ttcttctggt tcttctgctt gtgcatattt tttcagcaag cgtcgttctt catgtttggt
    28201 cattttcttc ttctgctctt ttttatcaag cattttttct gtcgttccat cgtatttaca
    28261 acggaaataa gcaccgtttt taccttcgat gatttccatt ttccggtgac attgcgggca
    28321 tcgatgatta gagacttttg gatcttttct tctgcggtag ttgcaatctg aattggtgca
    28381 gacatagatt ttgccgtcac gtgtgttttt ctcgcgcaga ttggccccac attctgggca
    28441 tttcttttgg gtaatcgaga aatcttgata ttcttgtttg cttgatttga tctcattcac
    28501 caagcgtttt gtttcttttt cgattccatt caagaaggtt cctgcttgtt tctttcctgc
    28561 agcaatagct tcaaggtctt tttcccagct ttctgtcaaa tctggtgtta ctaaagaggg
    28621 atttaccaat actaataatt gcttaccttt aggagatact tgcagtcctt gaggggtacg
    28681 ttccatcagt tcagatttga ttagtttctc gataatctct gcacgcgtag ctggggttcc
    28741 cagactgtat ttttccattt gaccaagcaa gcttgcttct gacaatggtt taggcggtgc
    28801 agatagttct tttttgatgg tgaaatcggg attgattctc atttcttttt cccatttgac
    28861 tgtttccgtc tcagtttcag tttcgccttt ccatcctgct tggacgacac gattttgccg
    28921 aaaaatgaat cgttctttac caaattcaac cgtaactttt gtttggctga ctttatgggg
    28981 ttgagcaaac agtcctaaaa aacgagagac aatcatttga tagatttttt gctcttcatt
    29041 acttaatttt tcataacgtg ctctgttttc agttggcaaa agtgcatggt gatcggtcac
    29101 tttactgtct tggaatactt ttgtctgttg gacgatggct ccgtttttca aatactgctt
    29161 gacctcagga gcaaagtcgc tgactgcttg caatcgttct ttcatcgtac ttttcatgtc
    29221 atttgtcaga tatttgctgt ctgtacgcgg ataagtaacg atcttatggg tctcatacaa
    29281 actttgtaca agacttaatg ttttctttgc agaatagcca tagcgttgat tggcttctct
    29341 ttggatctct gttaaatcat aaggcaatgg cgcagattcc gtttttaatt tttcttggac
    29401 ttctgtgaca gttcctttgc ttgtactgat caattgaaca agtttttgtg cttcttcttg
    29461 tgtttttaaa gcaaattgat ttttttgaag cattttggct tgttcttttc cagcttgcaa
    29521 cgtgatcgtg aaatacgttt gtggacggaa ctgctcgatt ttcttttctt ggtctctcac
    29581 taatgctagt gtcggtgtct gcacacggcc tgctgataaa ttatccgcgt acttcacagt
    29641 taaggctctg gtcacattca atcctaccag ccagtccgct tttgcccggg caagagcaga
    29701 ttcatacaat gcatcatatt ctttcgcagg tcttagttgc ttgaatccag ttttgattgc
    29761 tttatctgtt tgagaagaga tccataaccg cttcactggt ttattgaaat gcacatactc
    29821 taagatccag cgagcaacaa gttccccttc tcttccggca tctgtcgcaa tgactgcttc
    29881 tgagacatct tttcgctgag ccagctgctt gattgctttt aattgatgtc ctgttttagg
    29941 aagtggtttg attcctagtt ttttagggat cattggcaac gtgtccattt gccagctctg
    30001 ccattcctta ttcagatctt ccggcatttt caatcctaat aaatgaccaa gggcccaagt
    30061 aacgatcacc ttgggtcctt cataataatt tttgtgcttt tgattagcac caagcacctt
    30121 gcttaggtct ttcgcaacgc ttggtttttc cgctagaatt agttgtttca taaaattcct
    30181 ttccgctttc tactgtgatg ggctgatgat ttttcaacaa cgcaagtcct ttgtattgct
    30241 gtaaatcatc gtcacactct tcacaccagc gctcatctcc gtcattccaa aaggcgctga
    30301 gaaagttact ttttgcattg atatattcat aattttgatg gatttcgttc cattgttttt
    30361 cgtacgcttg tcgtgcttct tcgaaagact cgaatgtttc ttctgcttca atatcttctt
    30421 cccagtcttc aaaaaaccac caaggctcat tgtccccgaa catggtaatt acttgataca
    30481 tactcgtgct ccttctttca gcttttctag acttatctta gtcacttttc aagaaagttg
    30541 caagaatttt ctcttataaa aggatcattt aatgaacatc ttgaaaatga tataaatgaa
    30601 tctgattgtt taaggcaaag tagcgataaa gtcattgatc atccaaaaat agctgtcctc
    30661 tggatcgatt gtcgattctt ttgtaaagta tcctaaaaaa cgcaaggaaa gatagccgtg
    30721 gatcatacta cataattctc tgcttcggtg gactttttct tctttcgtta attgaaaagc
    30781 ctcaaagatc tgcaaaatga tctggttcgt ttcatggatt ccctctaata aaactgcttc
    30841 attggtgtgg ggcacactga tcagtaactc atacactgct tgatttgaaa aagcaaagga
    30901 tcgataagtt tctgcataga tctgcagtgc ttcctgacca ctttttccca caagagcccg
    30961 acgcagctgg tcattaagtt cctgcagaag tttcgctgtt agcgctgttt tgacatcacg
    31021 aatatttttg aaatggttat acagcgaggg agccttgata tccaagcgtt ttgctaaatg
    31081 ctgaaaggtt atttgctgaa catccatctc ttctgctagt tctcgaaagc agtcgatgat
    31141 tttctcttga gacagatttc tttttttcat tttcatgttt cctctcataa aataaatcct
    31201 tcactctttc agtttaccac gaaaaagaaa gagaaaaaag agactttcat tgataaacta
    31261 catattgtag tttataacaa aaagctgtag atgaaaattt tcagaaagaa ggagtctaat
    31321 tggctgcaag aataaaggaa aaattattta ggaaaagaga aacttgggaa caaaacttgt
    31381 ttgtcttatg gtttggaaca tttatggctg gtatcggatt tagtttagtc atgcctttta
    31441 tgtcacttta catagatacg ttaggtaatt atagtacgtc acaattgaac ttttggagcg
    31501 gattgacttt ttcatctact ttcttggtga ctacgctgat ctctccttgg tggggaaaat
    31561 tagcccacca aaaaggaaga aaattgatgc tgttgcgtgc ttcattagga atggcaatcg
    31621 tcatttcttt gatgggttgc gtgactagtg tgtatcaatt agtcgcattg cgtctgcttc
    31681 aagggatttt ttctggttat atcagtaatg ccgctgccct tgtcgcaact gggacgccaa
    31741 aagaaaaaag tggtcaagtt cttggaactt tagcaactgg ttctgttaca ggaacattac
    31801 ttggaccgct tcttggcggg atctctgctt cagcgtttgg ctatcgccct acctttttca
    31861 ttacagggat catcttattt ttcgtcttct tgttgagtct gtttttcgtc catgaaaaat
    31921 ttgtcccagt gaaaaaagaa aacatggttt ctgccaaaca gattttcaaa gacttgaaat
    31981 atccacacgt cgtcatcggt atgttcgtca caacgatgat catccaagca tccaacaatt
    32041 ccattagtcc aatcatcagt ctgtacattc gccaattgct gcatggacat gggaatgtta
    32101 cgttgatcag cggaatcatc gcttcgatac ctgggattgc cactttgata gccgctccaa
    32161 gatttggtcg cttaggtgac aagattggga gtgaaagaat acttgcgatt ggtttgggtt
    32221 ttgcgattct ggtttatatc ccaatggcat tcgtcacgaa tgtttggcaa ttagctgcct
    32281 tacgtttttt gatgggtatc tctgatgctt gtctgctccc tgctgtccaa gcattgatca
    32341 caaaatattc tcctcatcaa gctgctggac ggatcttcag ttataaccaa tctttccaag
    32401 caactggtaa cgtagtagga cctatgatcg gctccagtgt ttctagtgca tttggttatc
    32461 gtggcgtctt tctttcgact tctcttcttg ttttggtcaa cttcttgctt gtacgacaca
    32521 atacacaaga gatccatcag caagaaactg cagaagaaaa agcttcagga gtctccatat
    32581 cttcagggca ctctccttct catagacaat aagcgtaaat gaaaaacact gcttgaacag
    32641 ttgtcacaga ctgtccttgc agtgtttttg tttaggcctg ttttttcaag aactcagata
    32701 agaggaataa tcccttttcc aaggtttctt ttttacaaca gtaacctagt cgggcatgct
    32761 tcggtaaatc aaaggcactt cctggtacta atagtactcc tgtttcttct aataaattga
    32821 tacaaaatgt ctggtcatct tcttcgatgg ctaatttaat gaaagaagta gagacgtaat
    32881 tgggagcgac aagttcaact ttcggttcat tggctaccca ttgttttaaa atcacaaggt
    32941 tctctgtaat gatctttttg tttcgctcca atattttttc tttattcttc aatgcatgta
    33001 cagcaagatc atctgacagg actccgccgc aaatcatcgt gtagtctcga tactttcgaa
    33061 aaacttctgc caactcaggt ccagtagctg tccagccaat acgaatacct ggaatggagt
    33121 aggttttgga tagggaattg gttgctatac ctttttcata gacatctacg atcgacaaga
    33181 attcaccttt atccgttaaa ggcgcatata cttcatctat caatacatat gcatctactg
    33241 tacgagcaat ttctgcgatt ttttctaaag ttttccgatc tagcaatgtg cctgtaggat
    33301 tgtttgcact attcaaacag atgatttttg tttcaggttt gactaaggct tctagctgtt
    33361 ctaaatcaaa ctgccaatct tcttcttcct tcaaatgaac aaagtcaaca gcggcaccta
    33421 aagatttggg gatgtcatat aattgctgat aagtaggaag catcgaaaca acatggtctc
    33481 ctgcttccac taacgcgtat agagctaaaa gattagcacc agtcgctcca ttcgtttgta
    33541 agatgttttc cggatcgacg gtttgataaa gagaagcgac ttcttgtttg aaaacatctg
    33601 atccttcgat ccagccatag tccaatggtt cgtttttgcg tttttcgaaa aattcactta
    33661 cgctagtccc atctaagcca acgagttcgt ctaatgtcaa tgcttcgatc gagctttgtg
    33721 caatatcata taccgctttc ttttcccatt tatttagcca ttcttctaca ccgaaatttg
    33781 cgattttcat gtttctttcc cccttatatc ttgatccagc ctacagcaag caacccgatt
    33841 gaaagcagtg cggccacaca aatcagccca atcattactt tttcttttcc cgtaatttga
    33901 tgtttggttt cacgacaagc gatccagtag aagcaaaaac caggaagata ggcaatacta
    33961 cataaaagga cataagaaaa tcctgctaaa atgatgccca tcaattcaaa agctacagca
    34021 atcccaccga tcactacttg ttttttgatt ccttctttta aagaaaactg gacttgatag
    34081 atcccgacaa gtagataaca aatcaaaatt gccgctgtac ataaagaata ggcaaattga
    34141 taggcataat cagtaactaa gaaagtcaat aagaatagat tagtcaagat tgcagtaaca
    34201 actaacgaat aagttggggc atttttttta ttcgtttttc cccaaccttt cggcaacaga
    34261 ccgtctcgag ccatcaacat cgttgtttct gctgggagca tcgtccaaga caaccaagaa
    34321 ccaatgatcg aaataatcaa gccgatattg atcagcgctg ctccccaatt tcccacgatt
    34381 ccttttaaaa tatttgccat agcaggttgt gaaatagttg ctaactcttc ttgagataag
    34441 acgccgtatg gcaagatcga agcaaggata tagataaaca ataaacaaag cagaccaatg
    34501 atcgatgctt gctgggcttc tgaacgtttc ttcgcgcggt tggctaaaac acttgcgcct
    34561 tcgatcccta caaagaccca catcataacc atcaaacaac ctttaatctg caaccagatc
    34621 gttccttgct gccctgttcc attcactaga ttatcagata cgttacccca aaaatcagca
    34681 gtgaatatat tcactttaaa tgcgataaat acaaatatta aaaataggaa taatggcact
    34741 aatttacaga tcgtcacgat tgtattgatg acgctcgctc cttcaactcc attgtttact
    34801 aataaagtca gaccccaaat aaaaatactt gcaaataaaa tagaaggaac attttgtcca
    34861 cctttgaata tcgcgaaaaa ttctcccatg gcgctcatca gcatcgttgc aaaagcaaca
    34921 tttcccagcc acgcagacaa ccagtaaccc caaccactga tgaagccacc taatttacca
    34981 aatgaagctt ccgcgtaacc gaaaatacca ccatctagat ctggacgttt ttctcctaaa
    35041 tgattcagcg ataataccaa agctaaaata ccaatcccaa cgattatcca tgaaaggatc
    35101 gctggccctg gagctgcaga actagccaga tcacttgtga tcccaaacac accgcttccg
    35161 attgacgaac tgacaaccag agcaaccagt ccccatttgc taatacccgt tgatttcttt
    35221 tccatttcca tcaccctcac ttataaaatt gaacaaatca cttgcaaaag atttccttct
    35281 attttgcaac tgctcttgct taacaaaaag caactttatt catattattg gatattatga
    35341 actttttaca caagtatttc aagtataaaa tgaataaaaa ttaattttat tgcaaaaaaa
    35401 cagctatgct atccaaaaga aaaggtgttt cttttgttag ccatagctgt tttgattcat
    35461 ttaatatcgc ttaaacgtat tgtaaaactt ttgtttcttg atatgcgtgg tcgatcaaac
    35521 caccacccag acattccatt tcatcataaa atacaactgc ttgtccagga gtgattgcac
    35581 gtacaggttc gtcgaatacg acttctgcat gattatcatc caataagcga actgtcacag
    35641 gaacgtcttg ctgacgataa cggaatttcg ctgtacactt gaattctttt ggcattggtt
    35701 cattcgtcgt aaagtggatt tcacttgcat ccaagcttgt ggcatacaat gcaggatgat
    35761 ggaacccttg ccccacatat aatgtgtttg tcgctagatc ttttcctaca acaaaccagg
    35821 gttcttgcga atctcctccg ccaccgatcc ctagtccttg acgttgacca atcgtataat
    35881 acatcaagcc agcatgttgc cctttgactt caccatcaag agtgaccata tttccttttt
    35941 ttgctggcag atagttgctc aaaaattgtt tgaagttctt ttcaccaata aaacagattc
    36001 ccgttgaatc ttttttctta gcagtcgcaa ggcctgcgcg ttcagcaatt gcccgtactt
    36061 ctgatttttc catgccgcct agagggaaca tcgtttttga aagctgttct tgtgataatt
    36121 ggctaaggaa gtaagtttga tctttattat tgtctactcc acgaagcatg tggaccacgc
    36181 cgttttcatc gcgagtgact tgcgcataat gtccagtagc tacataatcg gcgccaagat
    36241 ccattgcata atccaagaat gctttgaatt tgatttcttt gttgcacatc acgtctgggt
    36301 taggtgtacg tcctgcgcgg tattcggcta ggaaatattc aaatacacga tcccaatatt
    36361 ctttttcaaa attcacagaa taataaggaa tcccgatttg agcagctact ttcgctacat
    36421 ccttataatc ttccgtggcc gtgcatacac cgttttcgtc cgtgtcatcc caatttttca
    36481 tgaatattcc gatcacgtcg tatccttgtt cctttaacaa aagtgctgtt acagatgagt
    36541 cgacaccgcc gctcatccct acgacaacgc gtgttttgct gttgtctgtc atgatatcac
    36601 catcatttca attagattct gaaacatcta cgagttgaag gtcgcaactt ttcagtattt
    36661 tacattatac gtcatatttc tgaaaatttc atcccttaat tatcaagtcg taaaaatact
    36721 gttctactgg acctattcag tacacaaaca tgatagtcaa ccaaaaaatc actcatcttt
    36781 tgagcattcg atataaaaaa ttggcatact cataaaaagg gccagccttt cggcaataag
    36841 gaataatttt ataaattgtg aaaaactatt tttcaaaatt gcttcttatc gcttaaagct
    36901 acacgtctca tttacaacct tttcttttta gatgttatga gttgctcaga taagtgattt
    36961 tgtttactct aagaaaaaag ggaggcaaaa gatacatgaa ttactttacc agtgatatgc
    37021 actttttcca tgaacgctta ttaggaaaaa acgactttgc tccgcggctc tttgcaaatg
    37081 tggatgaaat gaaccaacag ttgatcacta gctggaatgc agtaataaaa gaaaccgacc
    37141 atgtttatca tctaggcgac cttgctatgc atccgcaata tgaaaaagca aatgcagaaa
    37201 ttttggaact ggtcactcaa ctgcaaggaa caatccactt gatcaaaggg aaccatgaca
    37261 gtcgcgcttt tttccgttat ttagaaaaaa atgatcctag gcttactgac ggaagtccca
    37321 aattttattt ttatgatgta ggtgccatcg ttaaattcga ccatcaacaa tattacttga
    37381 ctcattatcc gatgttgctc gggcctaacg acactatccg caatcttcat ggacatatcc
    37441 atcattacag cgtacctatc gagaacgatg tcaatgtagg cgtagacgca ccggaaaggg
    37501 aactcttaaa ggaaaaacta ccatttggca ctccgttatc tgagcaacaa atcaaagaaa
    37561 tctatgaagc aaagaggaag tacgataggt cgtgaaaaaa ctgccctata tcaagtatta
    37621 aacaaataaa gataattact catatttttc atttgagtag gcttattgcc acaggaacat
    37681 taggatcaga aatggagttg taacaagact tctgtcacaa ctccattcca tactattcgt
    37741 ctttttacta atggtgttct tttaccaatt ttttctgtaa ttctttatca taatttcgag
    37801 cagctgacgt taaaaataaa acgattccgc ataataaaat cccgattcca gaaaacaaga
    37861 acattttttc tacccctaaa cgatcagcta atggtcctgc aaataataat ccaattggac
    37921 ctgccaggtt catcaaagag ttgaagttcc ctaagacacg acctaaaaca ttcgattcat
    37981 aactctgctg gatcattgcc atcagcagtg tattgaaata tggcgttgca caacctgctc
    38041 ctgcattcaa gataagaaag tacaagaacc cttgactatc gtttggaccc aatccgcttg
    38101 caccgatcgt caggcccata atgatgtagg ctataataat aggtttcatt cggtctttcc
    38161 atgttcctat aaaactgatc agtgcaccgc ctaagagcat tccgactgcg tagactactt
    38221 ccactgctcc cgcctgtcca acggaaccac caaagtaacc tagcgtcatc aatggataca
    38281 gactgattgc tggcatgaac aacagcatca caaatgcacc attgatcgtt atgtaccata
    38341 accctttgtt atccatcaat tgctgcagcc caaattttgc atctttaaaa atagtaagcg
    38401 gaacttccaa tatttcagga gaaacttttg ggatcttcac aaaaatcaat aagccgacac
    38461 caaaaactgc ccccaataca tctaataaaa taaggtaatt gacaggaacg actgaaaaca
    38521 aagccgcacc tagagctggc gcaatgatga aattcgctga ttggaccatt cctaactgtc
    38581 cattcgtcct tgttatgtga gaagatggaa cgattgtcgg cataatcgac tgatcgttgg
    38641 catttggaat gtttgtgcga ccgaacgcat aaacaaagac acaaaaacta gccaaatcgg
    38701 gaaggattct gaaatcgttc cgactactgc taaaataagc gcgaaaatcg ctacaataat
    38761 atccgtgaca atcaaaagag cttttttatc ccagcgatcc actagcggtt ctacaaatgg
    38821 gcttagtaaa accatgggaa tcattcctag taaagtagca aaactcaaaa ttgtcgccga
    38881 accggtttct cttgtcaaat accagatgat cgcatattgg acgaccatac tagtgattcc
    38941 tgacaaaaac tgtcccgata aaaagaacaa ataatttctc ttccaattcg ttaaaacgac
    39001 cgactgttca ttttccataa acatccctct tttctttttc attttgtata gcgtttgcac
    39061 aacaatcatt atacgggatt cttttttcaa aaaatacctt tttccctaaa taacaatcgt
    39121 ttcaatttaa atttctttac ttagaaacaa taaatcagca aaatattaaa aataacaaca
    39181 tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt tgtccttaca aagttagtca
    39241 tctaacaata ggccgtttca aaactagttg tctttttata tccacagatc attcgacttt
    39301 ttcgaataac ccacggctaa tcatcccatc catcagaaaa taaaatttat cttggctcat
    39361 tttctgtttt ggatctttga aaatattgac tgctttcaat ccatttgctg tagtgatcga
    39421 cattttcaat gtttgaatat cttttgatac agtgattttt aatttgaatc cttctttgct
    39481 ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg cctccgtttg tttctgtaaa
    39541 tccattatcg cgcaatgtat atctttttgc atcaggatgc aaacgatagc taattggtgc
    39601 gcccagtacc gttgctgttg tttcaaatgc catgattttc acctcgataa aattagtttc
    39661 tctttattat aaaagtttat cctgattttt actaggtttt tcagttaagt tccctaaaaa
    39721 atgaaggcgt tctctcagac atctgttcat ataagaatga cttcactagt tattttttga
    39781 cagcacgaac taattgttca aggaaatact ggatgtcgtc ttcggtattt cccaaaccaa
    39841 agctgatacg gatggattct tttagtatcg gtgtatcttc tccatacatt gcttctaata
    39901 cgtgtgaagg ctcgatatta cctgctgtac aagctgaacc agtagaaata gcgaccccat
    39961 taagatcaag cttcatcagt agcaaatcat ttgcttcgcc aattaagcga agattcaaca
    40021 catgagggag tttattcgtt aaatcaccat ttacttgata agggatttcg tttgcttcta
    40081 atgtatcaag aatcaattgc tggaatcctt tatatttgtt gttacgtgct tcacgttctt
    40141 caggtgacag cagttcaact gcttttgcca taccccagat ccctgctaaa ttttctgtac
    40201 ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa tgcagggata tttactccgt
    40261 ctcgtttata taagaaaccg acgccttttg gcccattgat tttatgagca gagatactta
    40321 ataaatcgat tcctaattct tctggatgga tcgtttggtt tccgtacgct tgtaccgcat
    40381 ctgtatggaa ataagctgga tgatccgcta aaagttcacc gatttctttg attggcatca
    40441 aatttccgat ctcattgttc ccatacatca cagagaccaa gatcgtatct tctcgtaacg
    40501 cttttttgac ctcttcgatc gacagattcc ctttttcatc tacaggcaga tatgtaacgt
    40561 caaacccctt tgtctctaaa tatttcatgg tattaagaac agcaggatgt tcgatagctg
    40621 tagtgattag atgtctgcct tctttttgac acgagaacgc tgtttctaag atagctgtat
    40681 tatccccttc tgttccccca ctgttaaaga tgatctcgtg aggttttgct tgcagactgt
    40741 ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc gtggcgacca aatccatgta
    40801 tgcttgaagg atttccaaac gtgtcttgca tgattgccgt catcgcttca attacttgtg
    40861 gatgcatggg ggtagttgcc gcatgatcca gataaatagt tttcacttca ttcatccctt
    40921 ccaaattatt gctaggcaca ttctagcata aaatagcgaa caaaccaaag aagagctcat
    40981 ttttgtctag aggacgtttc atgggcatag aaaaaaggag ctatgacaaa agtcttgtcg
    41041 cagctccttg aagctgctca cttgtgtcac aacttctttc cctctttttt ttgtttattc
    41101 gaattctttt tcttccagac ggaataacgg actcatcggt gtattttcat ggatgcgttt
    41161 gaccgcttct cccattaatt ctgaacatgt aacgattgtt aagttttctg gatgacgatt
    41221 ttcttctgtg aaaacagaat cagtgataca aatatctttg attggtgcat tgtctaaaat
    41281 acttttcgca tgatcggaca ataatccatg tgacgcacag gcatatactt cttttgcgcc
    41341 gttttctttt aatacatttg ctgctcgtgc aagcgttgct cctgtgttca agatatcatc
    41401 taccatgata catgtctttc cttgaacatc accgatcaca taaccaccct cagttgaagc
    41461 atcatctgca tgatctacga tggctaatgt gctgttcaaa tattctgaaa gactacgtgc
    41521 acgctgaaca ccgctgtttt ttggcgaaac aactacgatg tcatctcccg tcagacctaa
    41581 ttgacggtaa taatgagcaa acaacggcat cgtaaataaa ttatctacag gaatatcaaa
    41641 gaatccttgt acttgaaccg tgtgcagatc taaagtcagt actcgagttg cccctgcttc
    41701 ttcgatcaag ttagcgatca atttcgcagt gatcggttca tgaggtttcg ccgtgcggtc
    41761 ttgcctagca tacccatagt aaggcaatac gacattgatc gttttcgcac ttgctcgctt
    41821 cattgcatcg atcatgatca gtagttccat atagtagtca ttgacaggtg cattcgttga
    41881 ttgaacgata tacacatgat cccctcgaat actttcttcg atattgatgg aaatctcgcc
    41941 atcactaaat tgcttcacga cgcttttacc taattctgtt ccgaacactt tcgcgatttt
    42001 ttcagctaat ggacggttgc cattcaaact aaaaatcttc aacgtgtcat cctgatactt
    42061 attactcatg tagtcctccc caaaacttct ctattcttcg atagtttaac atatttttcc
    42121 aagattttct gttaatttca gcaaattctt aaggaagtga aactgttccg ttactccaac
    42181 tggcaggaat gactttatga taatcgcccc agttgtcgtg tactttgtaa taacgttctc
    42241 ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg attgccatat gtactgccaa
    42301 gtactttcaa aataccaatc atcacaggtt tgccttcacg tatacgtttt gtagctcgct
    42361 gccatgaacc tagaagagtt gctcgtgcac gctcatgatt gccattcttc tttaaaaaac
    42421 tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag tcctagtggt tggatctggc
    42481 tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt tttcttgcga atctcatttg
    42541 gaagcatcca ctccttacga tagtcttgat aataggcaag gagaactgct gccgcgtaag
    42601 taccacaaag atagcctgag ggggtagccc atttcttata cctcaaaaaa cgttcttctg
    42661 gcaatcccac ccagcaattt gcgagttcct ttcctgacct tttttcttcg atcaaagcgg
    42721 gaatatcttc ttttctgttg atccatctag ataactcgat tggctcttca ttgatcagct
    42781 tccatttttt acaagaaaga ccctcttgat aagtatattt tgctggagaa tattctaccg
    42841 gatgtcctga ttgatcgata atcacataac tttgatcttc aaaaaccaga gctaaaaaaa
    42901 gcaatttact ttttcttgac tgcagctgct gagtgctggc taatttttta atttttttat
    42961 ctactttgaa atataaaggt ttatccacta cttgattcag ttgggatcgc ctcctttttt
    43021 tcattataag tgaaggattg aaaaaaacaa atcagtttga ttgttcgaat tttcaatttt
    43081 ttatgttcta tttgttaatt ccttcatttt gtaagataat gggcacacga aacaaaaaag
    43141 gagcgatcga tgaatgaaca aagaacgatt gaaacaagat ttctatgaag cagtcaatga
    43201 agaatggcaa aaaacagcaa aaatccctgc agataaacca gctacaggcg gtttccaaga
    43261 tttagttgac gggatcgacc aacttttgat gggagaaaca gacgatctgc ttgcccatcc
    43321 agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca tattatcaac tggcaaacga
    43381 ttatgaccga agaaatgagt tgcatgctca accacttcaa cctataatcg aaaaagttga
    43441 atcattgcag tctttcgacg aattgaatga gcaatttcca gaatggctgt tggatacatt
    43501 accattgcca tttaatctgg atgtagatgc agatatgaag aatgcgcaaa cgaacgcctt
    43561 ctttgcttat ccgccttctt tattccttcc agataagacg tattatgcat cagaccatcc
    43621 caacggtgca caactaatag gcgttttctt tgatatggct gttcagttat tagagcttgc
    43681 cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa gcagtgcaat ttgataaatt
    43741 gattgctcct catgtaaaaa gtgcagaaga aaacgcagat tacagcaaaa tgtataatcc
    43801 gcaatctttt gatacattta ttaaatacac agataaactg gacttgaaaa aacttgtcac
    43861 gggtttgatt gggacaactc cagataaagt gatcgtaact gatccagtgt acttcgatca
    43921 tttgaatgac atcctgacag aagctcattt tccgttattc aaaagctgga tgatcattaa
    43981 aacagtacgt tctcttagtg gttatctatc agaagaattc cgccaagtca gcggaatcta
    44041 ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag aaaaaagcag cgtattacct
    44101 tgcctctgga caattcgatc aagtagttgg cgattactac ggaaaaaaat attttggcga
    44161 agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg atcgccgttt ataaaaaacg
    44221 tctagaagaa aatgactggc ttggggatgc aacaaaagaa aaagccgtca taaaattaaa
    44281 taacttaggt atccaagtag gctaccccga taagatccca gcattattcg accagttcaa
    44341 aacagtacct gcagatcagg gtggtacttt gctttcaaat actcttgttt tcagcaaact
    44401 cacattaaaa gatcgtttca gcaaatggaa caaaccagtg gatcgttcag aatgggaaat
    44461 gagtgctgac acggtcaatg cttattatca tccatttcgg aatgtgatcg tctttccggc
    44521 agcgatcctt caagcaccat tttacagtct agaacaatca agctctgcta attatggtgg
    44581 aatcggagct gttatcgctc atgagatttc ccatgcattt gataataacg gcgctttatt
    44641 tgacgaatat ggcaacttga acaactggtg gacagaagaa gatcttacac aatttcaaaa
    44701 caaagcacaa gcaatgatcg aagaattcga tggtctgcct tttgctgacg gaaaagtaaa
    44761 cggaaaatta accgtttcgg aaaatattgc tgatgcaggc ggtctaagct gtgcattgga
    44821 agcagcaaaa acggaatcag atctttctat cgaggaattc tttgtcaatt gggcaacgat
    44881 ttggcgtaca aaagcaaaaa aagaatacca acaactttta ctgcaaatcg atgtccatgc
    44941 ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt gacgaattct atgaaacatt
    45001 tggtatcacg gaacaagacg ctatgtatct agcgccagaa aaaagagtgc gaatctggta
    45061 agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa ggaatttggg aaaatcgctt
    45121 ctcaaatttt tgtgacattt cggcttattt ttcgaagaag ttacttctgg aataccatgt
    45181 attagaggtt gtgaaaaagc tgcttagttt caagtagtaa gaaaaatttt gtgaaaatgg
    45241 ctttccacat ttttgcataa atttgactta ctaccgagaa actggctttt gaacaccgtt
    45301 tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt agagaaaaaa acggaaaaat
    45361 agttcctcat attttgccgt ttgttgagct aataccgagg gtcagctgat tgaacaccgt
    45421 ttagtggaga gattgtgaaa aagctgtcct gcatcaagta ataagaacag ccaatcaaaa
    45481 gcagcaagga gaacctcatc tataaaaaga tagaaggaag tgagacatct attggtctca
    45541 tttccttcta tttttacttt cctcagtcaa ttgttttaca tcataaaagg agaaattcca
    45601 cttatttttt tcgctgtttc atgacataaa caactacacc gattaacaaa attcctccag
    45661 ctaatgctag caacgggtta ttaaattctc ccgtttttgg gagtccttga gtgccatttt
    45721 tttcactttc ttttgctgtc ctatccggat gagaaggttt tccatttggt tttccatttg
    45781 gtgattcatt tcctggattt tctctttctg gtttgtcatt tcccgggggc acatcggcag
    45841 tttctcgcac agtgatcgct ttttgctggg taacagattc tgtatgagca gaccattttt
    45901 ccccatcaaa tatttccgaa cgataagtga cttctagcgt atattctcct tttgaaggtg
    45961 ctgaaaaaat agcggtatga ttagaaaatt gagcacttga ctgtgtttca acgatttgga
    46021 tcttttctgg gaaataacgc atatcttcaa agacaggcgt tccttgattt ggtgtgaaag
    46081 ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt tccttctgca ttctccgcca
    46141 caccatttgc ttcttgtata ataatcggat tattttgttc atttggtttt gtctgatttg
    46201 gttcttgtac gattgcatac tctggatatt ccgaagacgg tgaggtttct ccgtcaaaaa
    46261 tagcacctac agataatgga agaccatcca ctctttcctt ttctgtttga cgattccccg
    46321 gtttaatctg catcagtcca tgaacatgga tacttccatt ttcatagcgc gtaacaggct
    46381 gctgaccttc tttcgaacat gtatttagag actcgatcca atcttttgat atggtatgtc
    46441 caagagtatt ttctgattgt ttctctcgtt cattccaata gtagttcaac gagtggtaga
    46501 tttgatcttc gttttgattc aatgggcgga tctgctctct catctcaaga ttctctgttc
    46561 ggaaagataa gataccagaa gcatggtagt ctgtgtttcc tgctgaagag gtataaagag
    46621 ccacattata tgaaccgtta ttaaaacttg tactgctatt gacgataata tctgttccgc
    46681 tattggaatc gattcctttc gcaagatttt cgaaagacaa actattgatc aattcatgag
    46741 ggcccgttaa agaagaaccg cccattttga atccattacc gttaccttct ccctcaattc
    46801 ctggtaccca gccgtttcga taagcaactg agtttttgat gattactttt ccgatcgaac
    46861 ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc attatgatac gcgatacaac
    46921 cgtcaaatac atttccttct cctattgtca gtttggccgc aaatccatcg gcatcttcaa
    46981 atcctggatc ggcattttca aaagatgtac agttcttgac taagttatgc gcgggccatg
    47041 cttcgaaagg atcatttgag ctaccgctga tttggattcc tgtatttcca ttccgataag
    47101 catgaatctc ttcgatcaaa ttatgatttc cagaaatctg taatcctttt tgcatagctg
    47161 cactatttgt aatgtcaaac cctcgtaaac cccagtagtg actgaacagt gtcatcccat
    47221 ttccagttcc tttaaaatca agtacaggac gcttgttttc tggatttttc tctgcaatca
    47281 actgaatcgg gttttctctt gtcccgttaa cgccttttgg aatcgtcaat cctctttcga
    47341 aggaataagt tccaggcgcc atgacgattg tctgcccagc atatgcgtat ctcaatgctt
    47401 gtgtcagaga taatggattt tgtctgcttc cgtttcctgc atctgaccct tctggtgtta
    47461 cataaactgt cgaatattta ggtttacggt agtccactgt atgaagaatc tcttttgttt
    47521 cataactagt catctctacg tattcttctg gcggatagtt tttatctggc gtaaaactga
    47581 aagtaaattc gttcgttcct tccatcagtt ttgtctgata atcaaattcc cgattcgcag
    47641 tgatagccaa gttttttgcg ttcttaagca cctctcctgt tgctttattt ttaattgtca
    47701 ataatccgtc agcatttgct ctaaaggaca tagtatgatc ttggtttcct gaatgattac
    47761 tagaggtcac agtgtaaatc ggatcaatca agcgagtagg tctttcttgc ccaggaggat
    47821 ctgtcgcagg atctgagtaa gcaacttcga ttccttctac cttgatcgtc atattccttg
    47881 ctgcagcaaa tcctgcataa ataaccgatt catctgaagc gtataatttt tcccagtcat
    47941 acatgatgtc agaagccatt tcttctcctg tttcaggatc gtaataatat gcctctaaac
    48001 cagtattcgt ttttttcatc tctacgtcca gtttagtaat cgagttcgtg gccggaaaca
    48061 gattcccatg accgtttccg aatatattat aagaacctgt ttctttttcc aagaaccctg
    48121 ctgaagtctc taaaggtgtt gtttccactg agacactccc aggagctggc gcagcttgcg
    48181 gatcttcaga tgatattcct gtgattgccc gtgtccccaa tccaagtcgc atcgtatatt
    48241 tgctgccgct cgtgttgacc acttcttgtc tatccgagtc ccagacatat tcgatccgac
    48301 tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc aaacaaatga ttttttggta
    48361 ctgcgtctct taccattaaa gcaaatcctt cttgggcatt cgtataggtc caagattcta
    48421 tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg gattgcttga taataatagg
    48481 tcattccatc tgatccgctt gactggaatt ttccgccgtt attcgtggaa gagagccgca
    48541 cgccgtcttc taatggttca atggcatacc tactagcact tgtgctttct ccgaaaacaa
    48601 cccctttcca ctcttcattt gcttcttcag attgcttttt tgtcttttca ttttctgatt
    48661 ctttcatcat aggatcattt ccttcttccg tatccatatc ttcactagtt cttggtattt
    48721 cctccattgt tgacatccct tcaatgttca cgtgtgcatt tccttcgttc acagactgtt
    48781 gttcgttagc agcaacttca acgacagaaa ttaaaaccgg ggtactgagc ataaggagat
    48841 tcatcattag cgcactgtat tttatacgtt tttttaacaa gtgtattcct cccgtaacaa
    48901 attagaaagc gtttacttaa agtattacct aatttatttt tactgtcaat aaaaaa
//
LOCUS       DADVXM010000012        47640 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.012, whole genome shotgun sequence.
ACCESSION   DADVXM010000012 DADVXM010000000
VERSION     DADVXM010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.012"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            31..219
                     /locus_tag="KB927_000775"
     CDS             31..219
                     /locus_tag="KB927_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBB6839710.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(277..630)
                     /locus_tag="KB927_000776"
     CDS             complement(277..630)
                     /locus_tag="KB927_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6839711.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            1161..1583
                     /locus_tag="KB927_000777"
     CDS             1161..1583
                     /locus_tag="KB927_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6839712.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            1580..1810
                     /locus_tag="KB927_000778"
     CDS             1580..1810
                     /locus_tag="KB927_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6839713.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            2308..2508
                     /locus_tag="KB927_000779"
     CDS             2308..2508
                     /locus_tag="KB927_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBB6839714.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            2535..3728
                     /locus_tag="KB927_000780"
     CDS             2535..3728
                     /locus_tag="KB927_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6839715.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(3796..5361)
                     /gene="guaA"
                     /locus_tag="KB927_000781"
     CDS             complement(3796..5361)
                     /gene="guaA"
                     /locus_tag="KB927_000781"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBB6839716.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(5420..6343)
                     /locus_tag="KB927_000782"
     CDS             complement(5420..6343)
                     /locus_tag="KB927_000782"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBB6839717.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            6539..7144
                     /locus_tag="KB927_000783"
     CDS             6539..7144
                     /locus_tag="KB927_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6839718.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            7452..8468
                     /locus_tag="KB927_000784"
     CDS             7452..8468
                     /locus_tag="KB927_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBB6839719.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            8609..9910
                     /locus_tag="KB927_000785"
     CDS             8609..9910
                     /locus_tag="KB927_000785"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBB6839720.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            9956..10618
                     /gene="deoC"
                     /locus_tag="KB927_000786"
     CDS             9956..10618
                     /gene="deoC"
                     /locus_tag="KB927_000786"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBB6839721.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            10639..11037
                     /locus_tag="KB927_000787"
     CDS             10639..11037
                     /locus_tag="KB927_000787"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBB6839722.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            11103..12185
                     /locus_tag="KB927_000788"
     CDS             11103..12185
                     /locus_tag="KB927_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6839723.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            12397..13959
                     /locus_tag="KB927_000789"
     CDS             12397..13959
                     /locus_tag="KB927_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6839724.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            13952..15085
                     /locus_tag="KB927_000790"
     CDS             13952..15085
                     /locus_tag="KB927_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6839725.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            15085..16041
                     /locus_tag="KB927_000791"
     CDS             15085..16041
                     /locus_tag="KB927_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6839726.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            16140..17306
                     /gene="deoB"
                     /locus_tag="KB927_000792"
     CDS             16140..17306
                     /gene="deoB"
                     /locus_tag="KB927_000792"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBB6839727.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            17330..18148
                     /locus_tag="KB927_000793"
     CDS             17330..18148
                     /locus_tag="KB927_000793"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBB6839728.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            18165..18872
                     /gene="deoD"
                     /locus_tag="KB927_000794"
     CDS             18165..18872
                     /gene="deoD"
                     /locus_tag="KB927_000794"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBB6839729.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(19170..19856)
                     /gene="gpmA"
                     /locus_tag="KB927_000795"
     CDS             complement(19170..19856)
                     /gene="gpmA"
                     /locus_tag="KB927_000795"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBB6839730.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(20028..20609)
                     /locus_tag="KB927_000796"
     CDS             complement(20028..20609)
                     /locus_tag="KB927_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6839731.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(20742..21425)
                     /gene="rpiA"
                     /locus_tag="KB927_000797"
     CDS             complement(20742..21425)
                     /gene="rpiA"
                     /locus_tag="KB927_000797"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBB6839732.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            21744..22157
                     /gene="rpsL"
                     /locus_tag="KB927_000798"
     CDS             21744..22157
                     /gene="rpsL"
                     /locus_tag="KB927_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBB6839733.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            22241..22711
                     /gene="rpsG"
                     /locus_tag="KB927_000799"
     CDS             22241..22711
                     /gene="rpsG"
                     /locus_tag="KB927_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBB6839734.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            22805..24892
                     /gene="fusA"
                     /locus_tag="KB927_000800"
     CDS             22805..24892
                     /gene="fusA"
                     /locus_tag="KB927_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBB6839735.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            25064..26251
                     /gene="tuf"
                     /locus_tag="KB927_000801"
     CDS             25064..26251
                     /gene="tuf"
                     /locus_tag="KB927_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBB6839736.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            26658..26966
                     /gene="rpsJ"
                     /locus_tag="KB927_000802"
     CDS             26658..26966
                     /gene="rpsJ"
                     /locus_tag="KB927_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBB6839737.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            26997..27626
                     /gene="rplC"
                     /locus_tag="KB927_000803"
     CDS             26997..27626
                     /gene="rplC"
                     /locus_tag="KB927_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBB6839738.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            27654..28277
                     /gene="rplD"
                     /locus_tag="KB927_000804"
     CDS             27654..28277
                     /gene="rplD"
                     /locus_tag="KB927_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBB6839739.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            28277..28567
                     /gene="rplW"
                     /locus_tag="KB927_000805"
     CDS             28277..28567
                     /gene="rplW"
                     /locus_tag="KB927_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBB6839740.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            28606..29439
                     /gene="rplB"
                     /locus_tag="KB927_000806"
     CDS             28606..29439
                     /gene="rplB"
                     /locus_tag="KB927_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBB6839741.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            29482..29760
                     /gene="rpsS"
                     /locus_tag="KB927_000807"
     CDS             29482..29760
                     /gene="rpsS"
                     /locus_tag="KB927_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBB6839742.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            29783..30130
                     /gene="rplV"
                     /locus_tag="KB927_000808"
     CDS             29783..30130
                     /gene="rplV"
                     /locus_tag="KB927_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBB6839743.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            30144..30800
                     /gene="rpsC"
                     /locus_tag="KB927_000809"
     CDS             30144..30800
                     /gene="rpsC"
                     /locus_tag="KB927_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBB6839744.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            30803..31237
                     /gene="rplP"
                     /locus_tag="KB927_000810"
     CDS             30803..31237
                     /gene="rplP"
                     /locus_tag="KB927_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBB6839745.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            31227..31415
                     /gene="rpmC"
                     /locus_tag="KB927_000811"
     CDS             31227..31415
                     /gene="rpmC"
                     /locus_tag="KB927_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBB6839746.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            31440..31706
                     /gene="rpsQ"
                     /locus_tag="KB927_000812"
     CDS             31440..31706
                     /gene="rpsQ"
                     /locus_tag="KB927_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBB6839747.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            31764..32132
                     /gene="rplN"
                     /locus_tag="KB927_000813"
     CDS             31764..32132
                     /gene="rplN"
                     /locus_tag="KB927_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBB6839748.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            32169..32477
                     /gene="rplX"
                     /locus_tag="KB927_000814"
     CDS             32169..32477
                     /gene="rplX"
                     /locus_tag="KB927_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBB6839749.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            32505..33044
                     /gene="rplE"
                     /locus_tag="KB927_000815"
     CDS             32505..33044
                     /gene="rplE"
                     /locus_tag="KB927_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBB6839750.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            33063..33248
                     /locus_tag="KB927_000816"
     CDS             33063..33248
                     /locus_tag="KB927_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBB6839751.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            33284..33682
                     /gene="rpsH"
                     /locus_tag="KB927_000817"
     CDS             33284..33682
                     /gene="rpsH"
                     /locus_tag="KB927_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBB6839752.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            33714..34250
                     /gene="rplF"
                     /locus_tag="KB927_000818"
     CDS             33714..34250
                     /gene="rplF"
                     /locus_tag="KB927_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBB6839753.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            34411..34767
                     /gene="rplR"
                     /locus_tag="KB927_000819"
     CDS             34411..34767
                     /gene="rplR"
                     /locus_tag="KB927_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBB6839754.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            34788..35288
                     /gene="rpsE"
                     /locus_tag="KB927_000820"
     CDS             34788..35288
                     /gene="rpsE"
                     /locus_tag="KB927_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBB6839755.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            35303..35482
                     /gene="rpmD"
                     /locus_tag="KB927_000821"
     CDS             35303..35482
                     /gene="rpmD"
                     /locus_tag="KB927_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBB6839756.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            35526..35966
                     /gene="rplO"
                     /locus_tag="KB927_000822"
     CDS             35526..35966
                     /gene="rplO"
                     /locus_tag="KB927_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBB6839757.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            35966..37261
                     /gene="secY"
                     /locus_tag="KB927_000823"
     CDS             35966..37261
                     /gene="secY"
                     /locus_tag="KB927_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBB6839758.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            37323..37970
                     /locus_tag="KB927_000824"
     CDS             37323..37970
                     /locus_tag="KB927_000824"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBB6839759.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            38161..38379
                     /gene="infA"
                     /locus_tag="KB927_000825"
     CDS             38161..38379
                     /gene="infA"
                     /locus_tag="KB927_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBB6839760.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            38412..38528
                     /gene="rpmJ"
                     /locus_tag="KB927_000826"
     CDS             38412..38528
                     /gene="rpmJ"
                     /locus_tag="KB927_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBB6839761.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            38546..38911
                     /gene="rpsM"
                     /locus_tag="KB927_000827"
     CDS             38546..38911
                     /gene="rpsM"
                     /locus_tag="KB927_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBB6839762.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            38939..39328
                     /gene="rpsK"
                     /locus_tag="KB927_000828"
     CDS             38939..39328
                     /gene="rpsK"
                     /locus_tag="KB927_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBB6839763.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            39408..40346
                     /locus_tag="KB927_000829"
     CDS             39408..40346
                     /locus_tag="KB927_000829"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBB6839764.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            40374..40754
                     /gene="rplQ"
                     /locus_tag="KB927_000830"
     CDS             40374..40754
                     /gene="rplQ"
                     /locus_tag="KB927_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBB6839765.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            41026..41865
                     /locus_tag="KB927_000831"
     CDS             41026..41865
                     /locus_tag="KB927_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6839766.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            41841..42710
                     /locus_tag="KB927_000832"
     CDS             41841..42710
                     /locus_tag="KB927_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6839767.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            42700..43497
                     /locus_tag="KB927_000833"
     CDS             42700..43497
                     /locus_tag="KB927_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBB6839768.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            43700..44446
                     /gene="truA"
                     /locus_tag="KB927_000834"
     CDS             43700..44446
                     /gene="truA"
                     /locus_tag="KB927_000834"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBB6839769.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(44779..47448)
                     /locus_tag="KB927_000835"
     CDS             complement(44779..47448)
                     /locus_tag="KB927_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBB6839770.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
BASE COUNT        15378 a         8760 c        10176 g        13326 t
ORIGIN      
        1 ttgaattaaa gtggaaagga ggagattgtt attataaact acaagtggat attgtgtcct
       61 atttgtggaa ataaaacaag actacgaata cgagtggata ctatacttaa aaatttccct
      121 ttatactgcc ccaaatgtaa gaacgaaact ttaattaatg ttcaaaaaat gaatataata
      181 acaatcaaag agccagacgc caagacgcag agccgataat ttgagaaatg aaactctcat
      241 cttatcggct ctttttgttt atctgaattt tactgactag ccttcaatat ttcttgcttc
      301 attgatacct tttgctagtg cttccattaa ggatagttct ttgtctgtaa agctatccat
      361 gtatttttct acctgtaacc ttcgagtgct tttaatcaaa ttatctgtag gtaagaaaaa
      421 ttcatcaata gatacatgga gtaatgatac aagatcatac agcacttgtg tacttgggtg
      481 ttgtcctttg ttttctatat ttgttaaata acgtgggtca atttcaatca ttgttcccac
      541 ttgttcacga gtgagacccc gtttcattcg agcctcttta atcgctaaac caacggctct
      601 aaaatcgtat ttatcttctt ttttacgcat actaaatcac ctctatacat tttactgttc
      661 ctatataacc ataaacaggt atagaaaaac atgttatata gtttatgagt tcctatagaa
      721 cactgtggaa tttattaatg cgatgaatcc aatttcaaat agaaaggtcg ctgattttat
      781 ttacctatac aactttataa aatttagtca tactcctaga aagtagataa aattggcgac
      841 ttaatggagg gaaaagtcgc catgagaaag ataatctgtc atctagttct cttaattaag
      901 ttcttatcaa aaaaacttat ccacctgtac tggatagata tgaccatcaa tgtggttttg
      961 cagattacat agatagaaaa atcaaagcat atgaacagag aaaacaatct gtttatgtgc
     1021 ttttttggtc acttaataaa tatcttttag gatttctctt catttatgca acaaatcccc
     1081 cgttcgtgtc ggggtttagt atgaagggag ataaagaagc acatgccact ccctttcacg
     1141 acagaaaggg ggtgaaaagc atgaaaccat cttcttttca agaaaccata gaaaatcagt
     1201 ttgactatat ctgcaaacaa gttattgaag atgaacgaaa agattacttc aaacatctag
     1261 acagactatc agcaaaagaa gtctcgtttt ctgatataga taactacctt gtcaactctt
     1321 tttctactgt tgatacgtac gtcactgatt tccaactatt taaattattt ggattaagaa
     1381 tcaatgttga aagtgattta ttaagtgaag ccctgcgtca tctttcagag aaaaaacgga
     1441 acattatttt acttcattac tttatggata tgagtgatgt ggagattgcg gagttactaa
     1501 atttgaatcg ttcgactgtt tatcgtcatc gaataagtgg actagccatg attaaagaat
     1561 tcatgaagga gtgtaaagaa tgaaaacagc ttatccaagg gttcccttcc ccctcattgt
     1621 aaaggcgaca gatggcgacg tggaagcaat taatcagatt gttaaacatt atcgagggta
     1681 tacctcaaaa cgttcattac gtcgcatgac agacgaatat ggaaattctc atatggttat
     1741 tgatgaaacc ctacgtggca gaatggaaac gaaactcatc tctaagattt tatcgttcga
     1801 aattaaatag tcccattttt tcgtggaagc gtgtcgaatc gtatccacgc ttcccgattt
     1861 gggaggtttg ttattccatc aaagcatatt gtgtgttcag taggttttga taggctaaca
     1921 agccaaacgt tctttgacaa ccaaataaag gcaatcgaat acgtttcggt aagaaaagag
     1981 ctgatgaact aacacgccat gacctacaaa attagtgagc gattcatgtt agtaattcga
     2041 aagtaatctt tagcaggatt gctgccatga ctttcttatc gtgataatga tactcccgta
     2101 tagccatagt ccgagcgtta gaagcgtcac aggcaatggg tacggctaca tgagaaccat
     2161 gcagaagtga aattcctgtg agctttgcta gagctgttcg attgctaaga tattcttctc
     2221 ttgtcagtgt attattataa aactatttga tataattata ggtgaatatt ggagttttcc
     2281 tagcctataa ttgggaaagg agtaataatg ataacggtca caaaaaagga tttagttgag
     2341 ctaggatatg gaacttcttt ttcagcagac atcataaaaa aagcaaaaga attgatgatt
     2401 acaaaagggc atatctacta tcaatctcga aagctagata gagtccctcg tgaagctgtt
     2461 gaagaaattc taggaattcg gttttcaaat gaaaacaggt ctgagtagtt tttgcacagt
     2521 aaggagtaaa aactatggtt aaagacccaa taaaaaaagc aaagaatgga acctattatt
     2581 ttcgtgcaaa tctaggttat gattctaaag ggaaaaaaat tcaaaaatat cgtagtggat
     2641 tcactactaa aaaagaagca agagaagaat attcgaaact gctattgatg aaaccagaag
     2701 aattaagtga gaataaggat aaaatgacgt ttaaacatta tatctttgaa attttccttc
     2761 catggtataa gacacaggta aagctcagaa catatgaaaa tcgcttacca actattaaga
     2821 agcatttctc ttattttgat aaaatggctg tttccgatat tgagcctatt gatgtgcaaa
     2881 attggcaact aaaattatca aagaagtgta agtcttctta tgtaagagct gttcaaggac
     2941 tattttcagt tgctatggat cgagcaattg tccttgggat aaccaccaca aatccatcta
     3001 agattattgg caatgtgaaa aagcaaaagt ctaaaattga attttggaca aaagaagaat
     3061 ttgaaaaagt aatctctcta atttacaaag aagattacta tcaacacttt ttatttatct
     3121 ctctgtggtt tttatttatg actggaatgc gaattggtga agctactgcc attcaatggg
     3181 aagatattga ttttgactca ggagtactaa ccatcaacaa aacactctat tacaagaatc
     3241 aatcgaatta tagatttgtt gaaccaaaaa caaaggcgag cgttcgtcat attgtattag
     3301 ataaatgcac attaacttat ttatccgaat ggaaggaagt acaacaaaat ctaattcaga
     3361 cagactttgt aatgagctat aacggtattc ctacccaaaa acatacacta tcatatgcta
     3421 ttgaacgcta tgctaagctg gctggtatcc atcgaatcag aatccatggg ttacggcatt
     3481 ctcatgcttc cttgttaatc agtatgggag aaaatccact tatcattaaa gatcgtctag
     3541 gacacgaaga tattgagacg actttaggaa cgtatggaca tctttatcct aacagtaatt
     3601 tcgaggtagc taacaaatta aatggagcca tttcctttaa agaagcaaaa caaaattatg
     3661 atacttcacc aaagaatcaa tttactgtag actacttgcg aaacaaagaa atgaaaaaag
     3721 tgcaataaaa gtgcagtaaa aagataagaa gagccagaaa cccttggtat aagaggattt
     3781 ctagctctcc tacaactatt cccactccac tgttgctggt ggtttagaag tgatgtcata
     3841 cacgatacgg ttgacgtggg ctacttcgtt tacgatacgt acagagattt tttgcaagac
     3901 ttcccatggg atacgggcaa agtcagcggt cattccgtcg attgaagtta cagcacggat
     3961 accgactgtg tagtcgtaag tacgtccgtc acccataaca ccgacagagc ggatccctgg
     4021 aagaacagtg aaatattgcc agatatcacg gtcaagtcca gcagctgcga tttcttcacg
     4081 caagatagca tcagattcgc gtacgatttc tagcttgtct tcagtgattt cgccaagaac
     4141 acgaatacca agaccaggac cagggaatgg ctgacgccaa acgattgaat caggcatgcc
     4201 taactgagtc cctaattcac ggacttcgtc tttgaataat gtgtttaatg gttcgatcaa
     4261 ttcaaattgc atatcttctg gcagtccacc tacattatgg tgagatttga tcgtctgtgc
     4321 tgtttctgta ccagattcga taacgtcagt atacaacgtt ccttgtgcta ggaaagagac
     4381 gccttcttca ccagcaagtt ttgttgcttc gtcatcaaaa acatatacga attcattccc
     4441 aatgatttta cgtttttgtt ctgggtcaga tacacctttc aacttgtcta agaagcgatc
     4501 tcttgcatcg actttgatga tgttcaagcc gaattttccg cctagacttt ccattacttg
     4561 ttccgcttcg cctttgcgta gcagaccgtg gtcaacaaag atagatgtca attggtcacc
     4621 gatcgctttt tgtaaaagaa ccccaacgac actagaatca acgccacctg aaagaccaag
     4681 caagactttt ttgtcaccaa cttgttcacg gattttttct acttgcatat cgataaagtt
     4741 atccattgtc cagttacctt cacagtgaca aacatcaaag gcaaagtggc gcagcaattc
     4801 gattccgtat tcggaatgac gtacttctgc atggaattgg ataccataaa aattacgtgt
     4861 tgtgtcttgg atagaagcaa tcggacaatc tttgcttgtt ccgactgttt caaagccttc
     4921 aggaacttta gttaccaagt caccatggct catccatact gtttgttgtt ttggtgtttc
     4981 tttaaacaag acagcttgat cgcttgttac ttctaacaag gctttcccat attcgcggtt
     5041 tttagcaggc tctacggaac cgccaagttt gtacgtgatc aattgcatac catagcaaat
     5101 ccctaataca ggaataccta aattgaagat ctcaggatcg atcccaaatg cattctcatc
     5161 atatacactg tttggtccgc cagaaagaat gattcccttt ggattcatcg cttttacttc
     5221 ttctgcagta atgcggtggc tcaataattc ggaaaagact ccaagatcac gaatacgtct
     5281 tgtgatcaat tggttatact gactaccgta gtctaatacg ataatctttt caacgttcgt
     5341 catatcggca acgtttgtca aatttattac ccctatccct ttaaatttta tctcaaaata
     5401 gtcaaactat tttaaaatgc taatattttc gcatgaaaat cgaatcgatg atatgatttt
     5461 cagttttatg gagaattata tcggctcttc ctcgtgtagg caagatatat tcctgtaaat
     5521 ttttcaaatt cacatttttc catacatctt ttgccatttt aaaggcttct tcacgatctc
     5581 cgatagcaaa acgataataa taattctctg gattttggaa agccgtatcc agtaacgcac
     5641 caaaacgatc caaataccat ttttcgatca gcacgggatc ggcatcgaca tagacagaaa
     5701 aatcaaaaaa gtcgctgacg tagatttgct gattcgcagg taattgaagc gtattgatcc
     5761 cctcaacgat caagatatca ggctgctgga tcaattcgta cttgtctgga atgatatcat
     5821 acacatcatg tgagtaaaca ggtactttta tctcttcctg accagatttt acacggttca
     5881 agaaatcgat cagcatctcc atatcataac tttcaggaaa tcctttacgg tccatgattc
     5941 cacgctcttt taatatacga tttggataaa gaaatccgtc agtcgtgatc agctgaacgt
     6001 ttcttcgttt gaaggtacga gacaaaatcg tctgcagcag tctggctgtt gtactttttc
     6061 caacggctac acttccggcg atcccgataa taaaaggcgg tacttctacg tatttatgaa
     6121 gaaataaacc tttactcaag aacaaagatt caaattcttt catataaaga taaatcagat
     6181 gagcaagagg tacatagata tctcgaacat cctgcatgga aatgcggtca ttcaaacttt
     6241 tgatattatc tagttcatct tgtgtcaaag gtgcttgccc attacgataa aattctcgcc
     6301 attcttctct tgccacacgg tagtagttca ttggatcatt catattagcc tcctgcgttc
     6361 tcccatcaat ggaactattt taacacaaaa taaacgcaaa ccccaccact taagagagat
     6421 tgccgatctt tttgtataat ctttataata gaaagaaacg gagtcttatt cttgacttgc
     6481 gcacggatac ataaaaggat agactgttgt catgaaagaa atgagaagga tggaagacat
     6541 gacaaatcat tactattctg aacgcccaga tacggcgcac gattttgaac aatgggcttt
     6601 tgagttaaaa ggcagaacct ttcaatttgt aacagattct ggtgtatttt cacgtgaaac
     6661 agtggattat ggttcacgtg tcctgattga tgctttcgat tgggaagagt tacctgatga
     6721 aggaaagatc ttagatgtgg gatgcgggta tggaccgatt gggttagctt tggcatttgc
     6781 gacacagcgg tttgttgaaa tggtcgacat taatgaacga gcggtaagtc tagcgcaagg
     6841 aaacgcaaag cgtaaccaaa tcgaacatgt tgatatccat caatcgaata tctatgaagc
     6901 agttcatgaa gaaacctatg cagctatcgt aagcaatccg ccgatccgtg ctggaaaaaa
     6961 agttgtacat gaaattttga caggcgcata tcctcggttg aagaagggcg gtacactgac
     7021 aattgtgatc cagaagaaac aaggagcgcc gagtgcgcaa aagaaaatgg aagaaacatt
     7081 tggtaatgca gaaatcgtca caaaagataa aggatattat atcatcaaaa gtgtgaaaga
     7141 ataactagct gaaaaatagt ggagcgacga aagagtggaa ctgggcgtgc atgtacgggt
     7201 acgtatcagt tctttttttg ttgagaagtt tttaaaaaca aagaactatt ttttcttcaa
     7261 aaagaaatag taggaacaga gtcgttgttt tttacgataa aataaataag atacagaact
     7321 tgtatagaag gctgccaagt cggtagataa aggaggtttt tatcaaaaaa catactttcc
     7381 ttttttctct attcttttct tgggggtttt ggtacactga tagggaattt agatagaagg
     7441 gagccaatag gatgaagctg accatcagag atatcgcaga aatggcaggc gtatcagtaa
     7501 caactgtctc acagattttg aataacaaag gaagcagatt tagtgataag acaagaaaaa
     7561 aagtgttgtc gatcgtgaat gaacatcatt ataagcccga ttatttcgct tcaaatgtga
     7621 tcaatcgaca ttcaaagacc atcggaatga tcgtccctga tgtcactgat ttcttcttct
     7681 ccaaactgat cgaaggtgta gagagctatt tgaatccttt gggctatgtg atcatgttat
     7741 gcaattctcg tcatagccaa gaaaatgaga tcaagtattt acaagagctt tcccaccgct
     7801 cagtggacgg aatcttgctg gccacaccaa atattttacc tgagaaatat gcattagaca
     7861 gcggttttta tcaaaaaatg ccaatcattt taatcgatcg cggattgaat cgtcgggata
     7921 acggacggct tatcgtaaag gaatatgagg gcgcctatca agctgtttcg ctgtttattg
     7981 aaaatggcca tacgaagatc ggcatgctga aggaaaccac tggatactat caattagaag
     8041 aacgtttcaa cggatatcgt catgcgctga aagatcatgg cctgcctttt aatgggaaat
     8101 ttgttgaaca tggagagttg actgtccaag gtggatatac tgcatcaaaa aaattactca
     8161 aacataaaga tatcacggct attttttgcg ggaatgatgc catggcgatc ggatgctatc
     8221 aggcgatcga tgaattgggc aaaaaaatcc cagaagatat ctcagtcata ggattcgatg
     8281 gattaaagct gtcagaatac atgattccgc aattgacgac agtgcagcag ccaagttttg
     8341 atattggatt ttatgctgca cgtttcctga tcgatacgat cgaatttcct caaagaaaag
     8401 ttccgaacaa agtgttcgaa acaaaattaa ttattcgtga gagcgtaaaa gtattgacaa
     8461 agggctaact cggcggtata ttgcttatgt aagcatttac aaaggctagt tagtgctttt
     8521 tttattttta gtaaaccagt ttactaaagt ggtttacctt tcctaaaaat aatgtataat
     8581 accgaatgaa gacaaggagg atcaggcaat gcgaatggtg gatctgattg aaaaaaagag
     8641 ggatggaaac gagctgtcga aagaggaaat cgagtacatc gtcacgaact atacgaatgg
     8701 aaagattcca gattatcaag tcagtgcatt attgatggca attttttatc aagacatgac
     8761 aaatgaagaa atcacgaact taacattggc gattgctaat tctggtgatg tcatcgattt
     8821 gagttctctt gaaggaataa aggtagataa gcattcgaca ggtggcgttg gtgacacgac
     8881 cacattgatt ttagcccccc tagtagctag tgtcggagtg acagtggcta aaatgtctgg
     8941 acgcggtcta ggttacacag gtggtacact agacaagcta gaagcaattc ccggatttca
     9001 gatcgagctt tcggatgaag aatttgtacg cattgttaat gaaagtaaag tagcggtaat
     9061 tggtcaatca ggaaacttgg caccggcgga caaaaaattg tatgccttgc gtgacgtcac
     9121 agcgaccgtt gattctcttc cgctgattgc cagttcgatt atgagtaaaa aaatcgcggc
     9181 aggagcagat gcaatcgttt tggatgtgac cactggagac ggtgctttca tgaagaacat
     9241 cgaagatgca agacgtctgg caaagaccat gacgagcatt gggaaactgg ctaaccgaga
     9301 aacagtggcg gttatctcag atatgtcaga acctcttggc gaagctatcg gaaatagtct
     9361 agaagttgtc gaggcaatcg aaacattaca aggaaatggt ccagaagatc tagtagaaat
     9421 gtgctacgcc ttaggaagcc aaatggttgt tcttgctggc aaagctaaga caaccgatga
     9481 agcaagaacg ttgcttcaag aagctctgga atcaggtaaa gcgttagcaa aattcaaaga
     9541 aatgatccaa aatcaagggg gagacccagc gatcgtggaa catccagaac gaattttgac
     9601 tgcacgctac acaatggagc ttcctgctaa acaaagcgga gttgtgtcaa aaatcgtggc
     9661 aaatgaatta ggaattgctg caatgatgct aggtgctggg cgtaaaacca aagaagaaga
     9721 tattgatcac gctgttggat tgaaactgca taaaaaaatt ggtgacactg tgacaaaagg
     9781 tgagtcacta ttgacgatct atagtaacga cgaagaaatc acttctgtca ttgaattatt
     9841 atataaaaat attgaaattg gtgaatcggc aatgaagcca acgttgattc atgacatcat
     9901 cacagaataa aggaaaaaag cggactttac cgttttaaag aaaaggggaa aagaaatgga
     9961 actaaaccga atgatcgacc atactatttt gaaagcagac gcatctaaag aagctgtgat
    10021 gcaaattatc gaagaagcaa aaaaatacca tttttattct gtctgcatca atccagcatg
    10081 ggttgcgcta gcgaaagaac aattacaagg tgagccagta gccgtatgta cagtaatcgg
    10141 gtttcctcta ggagcaaaca cacccgagac aaaagcattt gaaacaacag atgccatcaa
    10201 taacggtgca gatgaagtcg atatggtcat caatatcggt gctttgaaat caaaggatga
    10261 tcaacaagtc caaaaagata tcgaagcagt tgttgaagca gcaaaagatc gtgcgcttgt
    10321 caaagttatt attgaaacat cgttattaga tagagaagaa atcatccgag cttgcgaaat
    10381 agcaaaagct gcaggcgctg attttgtcaa aacatcaact ggtttctcaa caggcggagc
    10441 aaaggtagag gatgtccgtt tgatgcgtga aactgtagga ccagaaatgg gtgtcaaagc
    10501 ttccggcggt atccataacg aagaagaagc aatggcaatg atcgaagctg gtgctacaag
    10561 aatcggaaca agcgcaggag tagcaatcgt atctggttca actggtgaag gctattaatt
    10621 ttttcaaagg agaagctcat ggcagaactc aaacaagaat ggatcaacac agctattgaa
    10681 gcgttagata aagcctatgt tccttattcc cattttccgg taggcgcttg tctcgtaacg
    10741 gaatcaggca agatttatca aggcatcaac attgagaatg catcatttgg attaacgaat
    10801 tgtgccgagc gcacagcttt tttcaaagca gtatctgaag gagaaaaaac atttacgcat
    10861 ctagtcgtag cggggcacac ccccgatcct atctctcctt gtggtgcatg tcgacaagta
    10921 atggcagaat tctgttcccc tgatatgccg gttacgctag taggagacaa tggtgtgacg
    10981 aaggcaacga ccgttcgtgc actgctgcct tatgcattta ctgaaaaaga tctataactc
    11041 atgttcattc agtcagctga ctgttgaaaa ataaaacaat tattttagga ggctttacag
    11101 aaatgaaaaa agcaaaatta tttggtttag gtgctgtcgc actagcagca gggttatttt
    11161 taggtgcatg cggcaacaac ggctctactg attcatccgg tggcaaaagc tcatcagaca
    11221 caacaactgc agcattgatc acagacacag gtggtgtaga cgaccgttca ttcaaccagt
    11281 cagcttggga aggactagaa aaatggggga aagatcaagg actttcacga ggaaatgatg
    11341 gcttccaata tttccaatct tcaaatgaat cagattacat cccaaatatt gaccaagcat
    11401 tgaatgctgg attcaaaacg atttttggta ttggttataa actaaaacca gcgatccaag
    11461 aacaagcaac aaacaataca ggtacgaact ttgttattat cgatgatgtc atcgatggat
    11521 tagataacgt tgtatctgca actttcaaag acaacgaagc ttcttatctt gcaggtgttg
    11581 cagcagctta tacgactgaa acaaacgtag tcggctttat cggcggtgta aaaggtgaag
    11641 taatcgatcg ttttgatgct ggattcaaag ccggtgttga tgcaggtgcg aaagaattag
    11701 gaaaagaaat caaagtattg aatcaatatg ctggtgactt ctctgctcca gataaaggac
    11761 gttcaattgc tcaaggtatg tatgcacaaa acgcagatat catcttccat gcttcaggcg
    11821 gtacaggtaa cggtgtattc caagaagcaa aatcattgaa cgaatcaggc gacaaaaaag
    11881 tttgggttat cggtgttgac cgcgaccaat cagacgaagg cgaatacaca ttaaacggcg
    11941 aaaagaaaaa cttcacattg acatctacac tgaaagcagt tggaacagta gtagaagatt
    12001 tggcacaaaa atcagcggac ggtaaattcc ctggcggcga acacactgtt tatggattga
    12061 aagaagacgg tgttggtcta acagaaggac aactttctga cgaagcgaaa aaagcagttg
    12121 atgaagcaaa agaaaaaatc atttcaggtg acgtaaaagt tccagaaact cctgaagaaa
    12181 actaaaacca tttctatagc cttgttagac acatgtttga caaggctatg gtttgattag
    12241 aacaagaatt gttcatttat ccaagctgcc ttgtgacagt ttggataagg gaacaactcc
    12301 ctgaagtaat gtttgtttca aaagaagaac gctcactaag cgtgaatctt agtcaatcgt
    12361 tgccctagat agaaatcgtt aggatgtgaa aaaaaggtgg ttcaagaaaa tattgtcata
    12421 gaaatgcaga atattaccaa agaatttgga acattcaagg caaatgacaa catcaattta
    12481 caagtaaagg caggagaaat tcatgcgttg cttggagaaa acggtgctgg caaatctaca
    12541 ttgatgaacg tgctttccgg attattagag ccgacatcag ggaaaatttt gatgcgtggg
    12601 aaagaagtaa agatcacaag tccgaccaaa gccaaccaat tagggattgg gatggtccat
    12661 cagcacttta tgcttgttga tgcctttact gtaacagaaa acatcgtgtt gggaagcgag
    12721 cctagtcgcg cagggatgct tgaccataaa aaagcacgaa aagagatcca aaaagtttct
    12781 gaacagtatg gattgtcagt caacccagat gcttacgttc gtgatatttc agttggaatg
    12841 gaacaacggg tagaaatttt aaaaacactt taccgaggag cagatgtact gatttttgat
    12901 gagccgacag ctgtattgac ccctcaagaa attgatgaat taatcgtgat catgaaggaa
    12961 ttagtcaaag aaggcaagtc gatcattttg attacgcata agttagatga aatcaaagca
    13021 gtagctgacc gctgtacagt tatccgccgt ggaaaaggaa tcggtacagt caacgttaaa
    13081 gacgtaacct cacaacaatt agccgatatg atggttggaa gaacggtttc attcaaaacg
    13141 atgaaaaaag aagcgaagcc tcaagaagtc gttttgtcta ttgaaaatct agtggtgaaa
    13201 gaaaatcgtg gattagaagc cgtgaaaaac ttgaacttag aggttcgtgc tggcgaagta
    13261 cttggtatcg ctggaatcga tggaaacggg cagtcggagt tgatccaagc tttgactggt
    13321 ttgcgaaagg cagaaagcgg acatatcaag ctaaaagggg aagacatcac taataaaaaa
    13381 ccccgaaaaa tcactgaaca tggtgtagga cacgtgccag aagaccgtca taaatacggg
    13441 ttagtcctag atatgacatt atctgaaaat atcgcactac aaacctatca tcaaaaacct
    13501 tacagtaaaa acggcatgct gaattattca gtaatgaatg aacatgccag agaattgatc
    13561 gaagaatatg atgttcgaac aacgaatgaa cttgttcccg caaaagcttt atcaggcgga
    13621 aatcagcaaa aagcaattat cgctcgtgaa gtcgaccgag atcctgatct gttgattgtt
    13681 gcaaatccaa ctcgtggact ggatgtaggt gcgatcgaat ttattcataa acgtctgatc
    13741 gaacaaaggg acaaatacaa agcagtgtta ctgatcagtt tcgaattaga agaaatttta
    13801 aatgtttcgg atcgtattgc tgttatccat gaaggagaaa ttgtcggtat cgttgatccg
    13861 aaagaaacat ctgaaaatga attaggtcta ttgatggcgg gctatacctt agaagaagca
    13921 cgaaaagagt tagaaaaggg ggctggcgca catgaatgat cgcagcgaaa aattccgtaa
    13981 tttattagtg cctgtacttt cagttgtttt aggattgatc ttaggcgcga tattgatggc
    14041 tgcttttggt tttcagccca tccaaggtta ttcttctatg ctagatgcag cccttggttc
    14101 gcaaagaggg ataggtgaaa cgttaaggca agcaacgccg ttgattttta cagcattagg
    14161 tttttctgta gctaactcag ctgggttttt caatattggg ctttctggac aagcactttg
    14221 cgggtggatc gtcagtgtct gggtggcact tgcgtttcca gatctgccaa aagttgtttt
    14281 gcttccgtta tgcgtgatct taggtgcctt agctggtgcg atggcagcgg ctgttccagg
    14341 tttacttcga gcattttttg gaacaagtga agtgatcgta acaatcatga tgaactatat
    14401 cttattatac gtaagcacat ttgctttaca tgaagtgatg cctgaaagct atcgctcaag
    14461 tttggactct tccaatatga tcagtcaaaa tgcctcactg cggttaccat ggttaacaca
    14521 agcttttggc ggctctcgcg taaactcagg attattttta gcaatcatcg cgcttatttt
    14581 cgtttggctg ctgatgaaga aaacgacttt aggatttgaa atccgttctg ttggattgaa
    14641 tccttttgct tctgagtatg caggaatgag tagtaaacgt acgatcgttt tgtcgatggt
    14701 catttctggc gctttggcag ggcttggcgg tgtggttgaa ggattaggaa cgtatcaaaa
    14761 cttctttgtt caaacgactt cgctatctat tggatttgac ggaatggctg tttccttgct
    14821 tggttctgga tcagcaatcg gtattctttt atcagcgatc ttgttcagta ttttgaagat
    14881 cggtggactt ggcatgcaga caggagcagg tgttccgttt gagatcgtca atgtatcgat
    14941 tgctttgatt atcttctttg tcgggatcaa cttcctgatt cgtttcgtca tggctaaagt
    15001 cttccaaggg aaaaaacaag aagagatcgt tgcgacaata gaatcgaaac caacgaatca
    15061 aaaccatgaa gggggcgaac tataatgtcg actatcgaat taattgcctt gatccttact
    15121 tctacactgg tttattcaac accgctaatt ctaacgtcac taggcggaac tttttctgaa
    15181 cgaagcggga tcgtaaacgt agggctagag ggaatcatgg tcatgggtgc ttttagttcc
    15241 atcgttttca acttgacgat gagtccatca cttggttcta tgacaccatg gatcgctatt
    15301 ttagtgggtg gcgtcgtagg tatcctattt tctctgattc acgcagtagc aacagtcagt
    15361 ttgcgtgctg accatattat cagcgggaca gtaattaatc tgatggcacc tgctttaggt
    15421 gttttcttga tcaaagcatg gtatggtaaa ggtcaaactg ataacatcac gcagaatctg
    15481 gggtattttt ctttcccagg attagcagat attccggtca ttggaccaat tttctttaaa
    15541 aatacattct tacctgctta ttgtgctatt ttgattgctg tcctagcttg ggtgatcatc
    15601 ttcaagacga aattcggctt gcgcctccgt tcagttggtg aaaatcctca agctgccgac
    15661 acattaggta tcaatgtata tgctatgcgt tattcaggcg tactgatttc tggcttgtta
    15721 ggcggtatgg gcggtgctgt ttttgctcag tcgatttccg gtaacttttc agctggtacg
    15781 atcgttggac aagggttcat ctccatggct gctatgatct ttggtaagtg gaatccttta
    15841 ggggcaatgg gtgcctcatt gttctttggt tttgctcaaa gcttgagtat cattggcgca
    15901 caattaccag ttatttcttc gattccgcca gtattgctgc aaattgctcc atatttgctg
    15961 acaatcattg tgctggttgt tttcttaggg aaagcttctg gtccaaaagc aaacgggaag
    16021 aactatatca aatcaaaata atcttttagc gaataaaaag ggtgggttac gggaagtgtt
    16081 tttcgtctcg ccctttttgt tttaaaggca ataaaaataa aaagaaagaa ggaataatca
    16141 tgtttaaacg cgtacatctg atcgtcatgg attcagtagg aattggagaa gcaccagatg
    16201 ccgataagtt cggtgatgtt ggttctgata cattaggaca cattgcgaaa gaagcaggat
    16261 tgaacgttcc acatttagag cagcttggtt taggaacgat ccgtcctctt gaaggtgtgg
    16321 aatcagtgaa agatcatcaa ggctatgcga cgaaattaga agaagtttct gtagggaaag
    16381 atacgatgac aggccactgg gaaatcatgg gattgaatat caaaactcca tttcgtgtgt
    16441 ttcctaatgg attccctgat gatctgatca aacaaatcga agaattttct ggccgtaaag
    16501 tcgtatgtaa caaaccttat agcggaacag ctgttattga cgattacggt gaacaccaaa
    16561 tgaaaacagg cgatttaatt gtatatactt ctgccgatcc tgtccttcag atcgcggcac
    16621 atgaagaaat cattccttta gaagaattat atcggatttg ccaattcgtt cgtgatataa
    16681 caaaagatga tccgtatatg attggccgaa tcattgcacg tccgtacgtg ggtgaaccag
    16741 gagacttcac acgaacaagc aatcgccatg attatgcgtt gaatccattc ggacacacag
    16801 tccttgattc tttgaaagaa gcaggaaagg acgtgattgc tgttggaaag atcaacgata
    16861 ttttcaacgg acaaggaatc actgaatctg tccgcacgaa aagcaatatg gatggcgttg
    16921 accagctgct gaaagttatg aaaaacgatt tttcaggaat cagctttacc aatttagtag
    16981 attttgatgc attatacggt catcgtcggg atgtagtcgg ctatgcgcat gcgattgaag
    17041 aatttgactt acgaattcca gaattgcttg aagcgatgga agaagacgac ttgctaatga
    17101 ttacagccga tcacggaaac gatccgacgt ttactggtac cgatcatacg cgagaatatg
    17161 taccgttatt ggtttacagt aaaaaaatga aagaacaagg ggcattgcct caaggatatt
    17221 attcagatat ttcagcaacg attgctgaga actttagtgt ttcttcgact gaaaatggcg
    17281 aaagcttctt gaaattatta aaataatctt tttaaatagg agaaagcaaa tgaccaagtt
    17341 aagcgagatg ttacaagaaa cgacccagtt tatccttgat aaaggagtaa aagaaattga
    17401 ttttggtttg attctaggtt caggattagg tgaattagca gatgaaatcg aagatgctgt
    17461 aatgatttct tatgatgaga tcccgttctt tcctgtttcg acagtagttg ggcatgcagg
    17521 aaagctagtt tatgggtctc tggcaggcaa gaaagtgtta gccatgcaag ggagattcca
    17581 ctactatgaa ggtcattcca tgcaaacagt gacctatcca gtacgtgtga tggccggact
    17641 aggggcccat tcagtcattg tgactaatgc atgtggtggt gtcaacgaat catttgtacc
    17701 aggagatttg atgctgatta ccgatcatat caattttact ggtgaaaatc ctttgatcgg
    17761 tccgaatgaa gatgcaatgg gccctagatt tccagatatg agtcaagctt atacgcctga
    17821 ctatcaagca acagcaaaag cagcagcaga aaaactaggt ttggatctta aagaaggcgt
    17881 atatatgggc tattctggac caacttatga aacgcctgcg gagatccgaa tgtctcggac
    17941 aataggagcc gatgcagtag ggatgtcgac tgttccagaa gtcatcgtag cagctcacag
    18001 cggattaaaa gtgttaggaa tctcttgtat taccaactta gcagcaggta tgcaagcgaa
    18061 tctgagccat gaagaagttg tagaaacaac tcagagagtc aaacaatctt ttaaagcatt
    18121 ggttaaagaa acattgacat tattgtaata ggaggaacaa taaaatgagt gtgcatattg
    18181 aagcgaaaga aggcgagatc gccgataaga ttttacttcc gggagatcct ttgcgagcta
    18241 aatatattgc ggagactttt ttggaagatc cagtttgtta caatcaggta cgcggtatgt
    18301 taggctttac cggcaaatat aaaggagaac gtatttctgt tcaaggaaca ggaatgggaa
    18361 tgccatcagc caccatctat gcccatgaat tgatccagtc gtatggtgta aagaaattga
    18421 ttcgagtagg tacatgcggt gcattgtcaa aagacgtcca tgttcgtgat ttagtactag
    18481 cacaaggtgc agcgaccagt tcttcgatga tcgaaaaaaa tttccaagcc tttcattttc
    18541 ctccaatcag tgatttcaat ctattactga aagcatatga gatagctaaa gaaaagggct
    18601 atacggttca tgtaggaaat gttctttcgg aagattcttt ctacaaagat gatttgacag
    18661 agacgttcca attagctgaa cttggcgttt taggagtgga aatggaagca gcggctcttt
    18721 attacttagg cgcgaaatac catgtgcaga cattaagttt gatgaccgtt agcgaccatt
    18781 tgatcaccgg tgaagaaaca acagctgcag aacgtcaatc tacgttcaat gaaatgatcg
    18841 aagtaggatt ggaaacagcg atagcagaat aagaaggaaa tgaaaaagct gccctgcatt
    18901 aagtaataag aacatccaag caaaaatagc tcctcatgtt tttgacttgg ctggacttat
    18961 tattgcaaat gtaagctttt gaacaccgtt taccaagagg ttgtgaatct gccgtttaac
    19021 tctgagtcac aaggaacaat ttcaaaaaac agcttttcat gtttgatgaa tattgtgact
    19081 tgtgaccgag aagttggcag gagaaaaccg tttatacgaa aaaagggact gtgacaaatc
    19141 gtgtcacagt ccctttttta tagtgttttt tataggtagt attttttagc aactgttaag
    19201 tcatcattta attcataaac aagtggttga cctgttggaa tttcaagatc catgatgtct
    19261 tcgtcagaga taccttcgat atgtttagct agggcgcgta atgagttacc atgtgcagct
    19321 actaaaacag ttttgttgtc tagtaatgct ggagcaattt catcttgcca gaatggcaaa
    19381 gcgcgttcta atgtcacttt caagttttct ccaccaggaa tatcgcgttt gtctaacatt
    19441 gcgtaacgac ggtcatttgc tgcagaacct tcgtcagttt cttccattaa tggaggaaga
    19501 gtatcgtaag aacgacgcca gatgtgcact tgttcgtcgc cgtatttttc agctgtttct
    19561 tttttgttca aaccttgtaa tttaccatag tgacgttcgt ttaagcgcca tgatttgatt
    19621 tgtggtaccc aaagttgatc tgaatattct aagatcaagt tacatgtttt gattgcacga
    19681 gttaaaacag aagtgtaagc aacatcaaat tcgattccag cttctttgat tttgcgtccg
    19741 ccttcttttg cttcttcgat tccttctggt gctagattta catcagccca accagtaaat
    19801 tggttcaatg cattccattc actaagaccg tgacgagaaa aaactaattt tggcatgttt
    19861 agctctcctt ttaagatagg tttatatttc tgaaattttc agttctgttt tattgtacaa
    19921 ttttttggaa gagatttcca tcgaaaaatt agataagatt ctatgagaaa acaagtagag
    19981 aatataaaaa aacgaacagt gcccacgcaa ctgttcgttt ttaggtatta gatgcataat
    20041 tgctcgattt ctttttcagg taaattgata tatttataac atgttccaac tgaaacaccg
    20101 cattttgaag aaataaattg gatcgtttct tttttttcat aatagagacg tcggattttt
    20161 ttgatcgttt ttgcatcgat ttttggtctt ccgccgattt ttcctttttt acgagcttca
    20221 tctaatccaa ctaatgtacg ttctttgatc aatgcgcact ccatgtttgc taggttttcc
    20281 attaattgga aatagatttt tcccatttcg cgcgtatcga ttccttcatc aagactaatc
    20341 aagtgcagcc cgcgatcttt gaataattgc gtgagttctg ttaattgccg cgtagatttg
    20401 cctaatcgat gaagttggca aatgactagt gcatcgcctt gttgcatgtc agcgatcact
    20461 gactccaaat gaacagcagt agaatcattt tgttccactt catatgtctc atggaaaatt
    20521 tcttgacaac caaagtcaga taattgatca acctgagttg ttaaatcaac gtcatttatg
    20581 gttgtgcgtg cataaccaat aattttcatg gtgattcctt tctagcagtg attttctaac
    20641 tggatataac agtaaaaatg tagcataaag tacgtcaaaa agatagtttt ttcgcaaatt
    20701 ttccgctgtc tttttttatt ggatgatcaa gcagtttttc tttatttacg acggattgcg
    20761 tcaagaatct caacgccttt ttctgagccg acaactactt tagaaaccat gtttaggaaa
    20821 agcccatgtt ctactacccc aacaagttca tctaaatagg tagctaagct ttctggctgt
    20881 tcgatgactt ctagatgcag atcaatgatg taatgaccac catctgtggt taagacttct
    20941 ccgttttcgt ctgtacgcaa gacgggttgg aatctttttt cttcaaaaat atgaagtagc
    21001 tgttgggagc cataagggat cacttcaact gggagtggga acttcccaag tttatcgact
    21061 aatttagaag aatcaacgat ccaaatcgtt tcttttgagt acgtagcgac tattttctcg
    21121 aaaagcaaag cagcgccgcc gcctttgatc ccttgaaaat cagcactgat ttcatcagca
    21181 ccgtctattg tcaaatcgac tacggggact tcatcaatac tctttaacgg tattcctaat
    21241 ttttccgctt gttcttttgt cgcatttgaa gtagtaactc ctgtgatacg taaaccttct
    21301 tcacgcatac ggcgaccaat ctcttctacc atataatagg cggttgaacc ggtcccgaga
    21361 cctacgatca tcccgtcctt tacgaatttc gcggcttcaa tgccagctaa ttgttttaaa
    21421 ttcatctttg cgtccacctt tttttagttt gagcatcgtg ctttcctcac tattttagcg
    21481 tgatttacgg taaaaagata ccattctttt ttattccaat aaagcttttt caaaaaaaat
    21541 tgcatctctt gttgacatgt tttttcattc gtgatattct aacaaaggtg ctttatctac
    21601 aggtttctgt gaagaaacgt gctgactgtt tatcaaagca tatttgataa ggatgcagac
    21661 attgcattta ttttttatca caaaaaaaga accacctgga tgtgtggaac tagacgcaaa
    21721 tcgtgggaag gaggaaacaa ggaatgccta caattaacca attagtacgt aaacctcgta
    21781 aatcaaaggt ggaaaaatct aattcacctg ctttgaacaa aggatataac agctttaaga
    21841 aaactcaaac taacgtaaac tcacctcaaa aacgtggggt agcaactcgt gtgggtacaa
    21901 tgacacctaa aaaaccgaac tcagctttac gtaaatatgc acgtgttcgt ttgtcaaact
    21961 taattgaagt tactgcttat atcccaggga ttggtcataa cttacaagaa cacagtgttg
    22021 tattattacg cggtggtcgt gtaaaagact taccaggggt acgttaccat atcgttcgcg
    22081 gtgctttaga tactgctggt gttaacgacc gtaaacaaag ccgttctaaa tacggaacta
    22141 aaaaacctaa agcttaattt taattattaa acaaatgaaa cttgcttcta ctatatagaa
    22201 gtaattacta tgaacaatat ttcggaagga ggagttacgg atgccacgta aaggtcctgt
    22261 tgcaaaacgt gatgttttac cagatcctat ttataactca aaattagtaa ctcgcttgat
    22321 caaccgtgta atggttgacg gaaaacgcgg gattgcagct aacattatct ataatgcctt
    22381 tgacttgatc aaagaatcta caggtaacga tccattagaa gtgtttgaac aagcaatgaa
    22441 aaacgttcaa cctgttcttg aagttaaagc acgtcgtgtt gggggttcaa actaccaagt
    22501 accagttgaa gttcgccctg aacgccgcgt tactctaggt cttcgttggg tagtaaacta
    22561 cgctcgcttg cgcggtgaac acacaatgga agaacgctta gcaaaagaaa tcatggatgc
    22621 tgcaaacaac acaggtgctt ctgttaaaaa acgtgaagac actcataaaa tggctgatgc
    22681 caaccgtgcg tttgctcact atcgctggta agattctctc tgtttggtcg gcttttataa
    22741 gtcgacctca gatagtgtcc ttatttttag caactagata gtaaagagag gagaaacaag
    22801 gagaatgacc agagaatttt ctttacaaaa cactcgtaat atcggtatca tggcccacat
    22861 cgatgctggt aaaacgactg ctactgaacg tatcttgtac tatactggta aaatccataa
    22921 aattggtgaa actcatgaag gagcttcaca aatggactgg atggaacaag aacaagaacg
    22981 tggtattacg atcacttctg ctgctactac agcacaatgg aagggtcacc gaatcaacat
    23041 catcgacaca ccaggacacg tagacttcac agttgaagtt gaacgttcat tgcgtgtact
    23101 tgatggtgct gtaactgttc ttgatgcaca atcaggtgtt gaacctcaaa ctgaaacagt
    23161 ttggcgtcaa gcaacaactt atggtgtacc tcgtatcgta tttgcaaaca aaatggacaa
    23221 gatcggtgct gacttcttat attcagtatc aactttacat gaccgtttgc aagcaaacgc
    23281 tcacccaatc caattaccaa ttggtgcgga agacgacttc acaggaatta tcgaccttgt
    23341 aacaatgaag gctgaaatgt atacaaacga tcttggaaca gagatcgaag aaacagaaat
    23401 tcctgaagaa taccgcgaat tagctgaaga atggcgcgaa aaattggttg aagctgtagc
    23461 tgaaactgat gaagaactta ctttgaaata cttagaaggt gaagaaatca ctgaagctga
    23521 gttaaaagaa ggtatccgcc gcgcaacagt taacgtagaa ttctacccag tactatgtgg
    23581 ttcagcattt aagaacaaag gggttcaatt actattggac gctgttcttg attacttgcc
    23641 atcaccgtta gatatcccag ctatcaaagg gattgaccct aaaactgatg aagaagtaga
    23701 acgtcctgca gacgacagcg ctcctttctc agctttagca tttaaagtta tgactgaccc
    23761 attcgtaggt cgtttaactt tcttccgtgt gtactctggt gttttacaat caggttcata
    23821 cgtacaaaac gcaacaaaag gcaaacgtga acgtgttggt cgtatcctac agatgcatgc
    23881 caactctcgt tcagaaatct ctgaagttta cgctggagat atcgctgctg ctgttggttt
    23941 gaaagacaca actactgggg acacactatg tgatgaaaag agtctagtta ttcttgaatc
    24001 catggaattc ccagaaccag ttatccaagt cgctattgaa cctaaatcaa aagctgacca
    24061 agataaaatg ggtgtggctt tacaaaaact atctgaagaa gatcctactt tccgtgctga
    24121 aacaaacgtg gaaacaggcg aaacaatcat cgctggtatg ggtgaacttc acttagatat
    24181 catcgttgac cgtatgcgtc gtgaattcaa agttgaagct aacgtaggtg cgcctcaagt
    24241 atcttaccgt gaaactttcc gtgctggcac tcaagccgaa ggtaagtttg tacgtcagtc
    24301 tggtggtaaa ggtcaatacg gtcacgtatg gattgaattt acaccaaatg aagaaggtgc
    24361 tggtttcgaa tttgaaaatg cgatcgtcgg tggggttgtt cctcgtgaat acattccagc
    24421 tgttgaaact ggtttgaaag atgctatgga aaatggtgtc ttagctggct atccattagt
    24481 agatatcaaa gctaaacttt acgatggttc ataccatgat gtcgattcaa atgaaactgc
    24541 cttccgtgtt gctgcttcta tggcattacg tgcagcagct aagaaagcta atccagtaat
    24601 ccttgaacca atcatggctg tagaagttgt tatccctgaa gattatttag gtgatgttat
    24661 gggtcacgta actgctcgtc gtggacgtgt tgaaggtatg gaagctcgcg ctggcggcca
    24721 acaagttgtt cgtgcgatgg ttccacttgc tgaaatgttt ggttatgcta caactcttcg
    24781 ttctgctact caaggtcgtg gtacatttac aatgacattt gaccactacg aagatgtacc
    24841 aaaatcagta caagaagaaa tcattaagaa aaacggcgga aaagctgaat aatttcttaa
    24901 aaccggatag tcctgcaaag agattatcca aagagactat atttttaata tagtttcgtg
    24961 taaaataatt atcgatgata tgggcatgtg gtgtaccttg tgtacatcat atacctatca
    25021 gacaaataaa aaatatattg tatttttagg aggacatttt aaaatggcaa aagaaaaatt
    25081 tgaccgttct aaaccacacg ttaacattgg tactatcgga cacgttgacc atggtaaaac
    25141 tacattaaca gctgcaatca caactgtact atctaagaaa aacggcggcc aagctatggc
    25201 ttacgatcaa atcgatggtg ctccagaaga acgcgaacgc ggaatcacaa tctcaacagc
    25261 tcacgttgag tatgaaacag atacacgcca ctacgctcac gttgactgcc caggacacgc
    25321 ggattacgtt aaaaacatga tcactggtgc tgctcaaatg gacggagcta tcttggtagt
    25381 ttctgctgct gacggcccaa tgcctcaaac tcgtgaacac atcctattgt ctcgtcaagt
    25441 tggtgttcct tacatcgttg tattcttgaa caaagtagac atggttgatg acgaagaatt
    25501 actagaatta gttgaaatgg aagttcgtga cctattaaca gaatacgaat tccctggtga
    25561 cgatgttcct gtagttgctg gatcagcttt gaaagctcta gaaggcgacg cttcatacga
    25621 agaaaaaatt cttgaattaa tggctgcagt tgacgaatac atcccaactc cagaacgtga
    25681 caacgacaaa ccattcatga tgccagttga agacgtgttc tcaattactg gacgtggtac
    25741 tgttgctaca ggtcgtgttg aacgtggaca agttcgcgtt ggtgacgaag ttgaagttgt
    25801 tggtattgct gaagaaactt caaaaacaac agttactggt gttgaaatgt tccgtaaatt
    25861 gttagactac gctgaagctg gagacaacat tggtgcttta ctacgtggtg ttgcacgtga
    25921 agacatccaa cgtggacaag ttttagctaa accaggtaca atcacacctc atacaaaatt
    25981 ctctgcagaa gtatacgtgt tgacaaaaga agaaggtgga cgtcatactc cattcttcac
    26041 taactaccgt ccacaattct acttccgtac aactgacgta acaggtgttg ttgaattacc
    26101 agaaggaact gaaatggtta tgcctggcga caacgtaaca atggaagttg aattaatcca
    26161 cccaatcgct atcgaaaacg gtactaaatt ctcaatccgt gaaggcggac gtacagttgg
    26221 tgccggtgtc gttacagaaa tcaaagctta attcacttaa gttttaaagt aaagcaacat
    26281 ttattcggac gtaatcgctc ggaacgaagg tcttaggatc tttgttccga gcttttttat
    26341 ttattgcagg atcaggaaaa aagacaggag tattataaat agaagaaaca cgaaataaaa
    26401 gagtcagtat tttctaaatg aaactttatg aaaacaaaat gttttttaca agaaaaagcc
    26461 ttgctttgtg agtttatata tattataatg acaaaggtgc gtttacttta gtgaattgca
    26521 cagacgtaat cagaatgatt tcgtcggcta agaaacgaga ggttgcgaca cgcccggacg
    26581 ctttgccacg aacgagcgtg acggaaattt tcgtggagct atgtctactt ttcaaaatag
    26641 gcgaaggagg gaacaagatg gcaaaacaaa aaattcgtat ccgtttaaaa gcgtatgaac
    26701 accgtatttt agatcaatca gcggataaaa tcgtggaaac tgcaaaaaga actggagcta
    26761 gcgtgtctgg tccaattcca ttaccaactg aacgcagtct ttacacaatc atccgtgcga
    26821 ctcataaata caaagattca cgcgaacaat tcgaaatgcg tacacacaaa cgtcttatcg
    26881 acattgtgaa cccaacacca aaaactgttg atgctttgat gaagctagac ttaccatctg
    26941 gtgtaaacat cgaaatcaaa ttataaaact aaaacaaaaa taatggaggt gtactcatga
    27001 ccaaaggaat cttagggaaa aaagtgggaa tgacacaaat cttcactgaa tctggtgaat
    27061 taattccagt aactgttgta gaagctactc caaacgtagt actacaagtg aaaacaatgg
    27121 aaacggatgg ctacgaagct attcaagttg gttaccaaga tatgcgtgaa gttttatcaa
    27181 acaaacctgc gaaaggtcat gttgcaaaag caaacacggc tcctaagcgc ttcattcgtg
    27241 aattcaaaaa tgttgagcta ggagaatatg aagtaggaaa agaaattaca gtagatgttt
    27301 tccaagcagg agacattatt gatgtaacag gtactacgaa aggtaaagga ttccaagggg
    27361 ttatcaaacg ccacggacaa agccgcggac caatggctca cggttctcgt taccatcgtc
    27421 gtcctgggtc aatgggtcca gttgcaccta accgtgtatt taaaaacaaa cgtcttgctg
    27481 gccgtatggg tggcaaccgc gtaactatcc aaaacttgga agttgtacgt gtcgatgcag
    27541 aaagaaatgt tatcttgatc aaaggtaatg ttcctggagc taaaaaatct ttaattacta
    27601 tcaaatcagc tgtgaaagct aaataattgt aggaagaaag gaggaactaa ggaatgccga
    27661 atgtagcatt attcaaacaa gatggaagcc aaaacggtga aatcacactt aacgaagaaa
    27721 tcttcggaat tgaacctaat gaaagtgttg tttacgatgc aatcgtaatg caacgtgcgt
    27781 cattaagaca aggaacacac gcggttaaaa accgtagcgc tgttcgcggc ggcggacgta
    27841 aaccatggcg tcaaaaagga acaggtcgtg cacgtcaagg atctatccgc tcaccacaat
    27901 ggcgtggagg tggcgtagtc tttggaccaa caccacgttc ttacagctac aaacttccta
    27961 aaaaagttcg tcgtttagca atgaaatctg tattgtcaga aaaagttgct gaaaacaact
    28021 tggtagcaat cgaaggcttg aacttcgacg caccaaaaac aaaagaattc aaacaagttc
    28081 ttgctaactt atctatcgac tctaaagtat tggttgttct agaaaaaggt aacgactttg
    28141 ctgctttatc agcacgtaac ttaccaaacg tttctgtagt aacttctgat aatgtgagtg
    28201 tgctagacgt tgtatcaaat acaaaagtgt tagcaacaca aactgctctt actcaaattg
    28261 aggaggtgct tgcataatga acttactaga cgtaatcaaa cgcccagtga tcactgaaaa
    28321 atcaatgctt gccatggatg acaagaaata cacttttgaa gtggacactc gcgcaaacaa
    28381 aactttagta aaacaagcgg tagaagctgc ttttgacgtt aaagtcaaaa acgtgaacat
    28441 cgtgaacgta cgtgcgaaat tcaaacgtat gggcaaatat gcaggatata caaaaaaacg
    28501 tcgcaaagcg atcgttacat tgactgaaga ttcaaaagaa atccaattat tcgaagctgc
    28561 tgaataagca ctaatagata actcattaaa ttaggaggga aaaacgtggc gattaaaaag
    28621 tacaaaccta cctcaaatgg tcgtcgtaac atgacaggtt ctgattttgc tgaaatcaca
    28681 acatcaacac ctgaaaaatc attgttacaa ccattgaaaa accatgctgg acgtaacaac
    28741 aacggccgca tcactgtacg tcatcaaggt ggcggacaca aacgccaata tcgcgtgatc
    28801 gacttcaaac gtaacaaaga taacgttgtt gcaactgttc aaacgatcga atatgatcca
    28861 aaccgttcag ctaacatcgc gttagtacac tatgaagatg gagtgaaagc ttacatctta
    28921 gcacctaaag gactagaagt gggtatgaaa cttgtttcag gtccagaagc agatatcaaa
    28981 gtcggaaatg ctcttccatt agaaaacatt ccagttggta ctgttatcca caacattgaa
    29041 atgaaacctg gtaaaggtgg acaattgatc cgttctgctg gtacaagtgc tcaagtactt
    29101 ggtaaagaag gcaaatacgt attgatccgc ttgaactctg gtgaagttcg tatgatctta
    29161 gctgcatgcc gtgctacaat cggttctgta ggtaacgaac aacacgaatt aatcaacatc
    29221 ggtaaagctg gacgctctcg ttggatgcgt aaacgcccaa ctgtacgtgg tagcgtaatg
    29281 aaccctaatg atcacccaca cggtggtggt gaaggtaaag ctcctatcgg acgtaaagca
    29341 ccagtttctc cttggggtca accagctctt ggttacaaaa ctcgtaacaa aaaagctaaa
    29401 tcagacaaac ttattgttcg tcgtcgcaaa aataaataat tactttgacc atgtgtcgca
    29461 cattttgaga ggaggttcac catgggtcgt agtttaaaga aaggaccttt tgtcgatgag
    29521 catttaatga aaaaagttga agctcaagca ggggttgaaa agaaaaaagt tatcaaaact
    29581 tggtcacgcc gttcaacagt tttcccaagt tttgttggat ataccatcgc agtttatgat
    29641 ggacgtaaac atgtaccagt ttacatccaa gaagacatgg taggacacaa attaggtgaa
    29701 tttgcaccta caagaactta tcgtggacat gctgctgacg ataagaaaac gaaacgctaa
    29761 tttgagggga ggataaatcc aaatggcaga acaaatcaca tcagctaaag caactgcaaa
    29821 aacagttcgc acttcacctc gaaaagcccg tttagtaatt gaccttatca gaggtaaaag
    29881 tgtcgcagat gcaatttcaa tcttgaaatt cacaccaaac aaatctgctg gaatcattga
    29941 aaaagtattg atgtcagcag ttgcgaatgc agaaaataac tttgacttag atgttgaaaa
    30001 cttggtagta agcgaagctt ttgttaacga aggacctaca atgaaacgtt tccgtcctcg
    30061 tgcaaaagga tcagcttctc caatcaacaa acgtacaagt catatcacgg tagtcgtatc
    30121 agaaaaataa ggagggataa tcagtgggtc aaaaagtaca tccaattgga atgcgtgtag
    30181 gcatcatccg cgactgggat gctaaatggt atgctgaaaa agagtatgct gagttcttac
    30241 acgaagattt aagaatccgt aaatttattt caactaaact tgctgatgct gctgtatcaa
    30301 cagttgaaat cgaacgcgca acaggtcgcg taaacatttc aattcacaca gctaaaccag
    30361 gtatggttat tggtaaaggc ggttctgaag tcgaaagcct aagaaaagaa ttaaacaaat
    30421 taactggtaa aagaatccat atcaatatcg tggaaatcaa aaaaccagat ctagatgcaa
    30481 aattagtagg tgaaggaatc gcacgtcaat tagaaaaccg tgttgctttc cgtcgcgctc
    30541 aaaaacaagc catccaacgc tcaatgcgtg ctggcgctca agggatcaaa actcaagtat
    30601 ctggtcgtct aaacggagca gatatcgctc gttcagaagg atactcagaa ggaactgttc
    30661 ctcttcatac tttacgtgcg gacattgatt acgcatggga agaagcagat acaacatacg
    30721 gaaaactagg agttaaagtg tggatctatc gtggagaaat tcttccaact aaaaaaaaca
    30781 ctgagaaagg agggaaataa tcatgttagt acctaaacgt gtaaaacacc gtcgtgaatt
    30841 ccgcggaaaa atgcgcgggg aagctaaagg cggaaaagaa gtagcattcg gtgaatacgg
    30901 tttgcaagct gttgattcac attggatcac aaaccgccaa atcgaagctg ctcgtatcgc
    30961 aatgactcgt tacatgaaac gtggtgggaa agtatggatt aaaattttcc ctcacaaatc
    31021 ttatactgcc aaagcaattg gggtacgtat gggttctggt aaaggggcac ctgaaggatg
    31081 ggttgcacca gtaaaacgtg gtaaaatcat gtttgaaatc gcaggcgttc ctgaagaagt
    31141 agctcgtgaa gcgttacgtc tagcttctca caaattacca atgaaaacta agatcgtaaa
    31201 acgtgaggaa atgggtggtg aatcgaatga aggttaaaga aatcagagaa ttaaccactg
    31261 ccgaaatgct tgatcaagaa aaacaattaa aagaagaatt gtttaatctt agattccaat
    31321 tagcaacagg tcaattagaa aacactgcac gtattaaaga agtacgtaaa tcgattgcac
    31381 gcatcaaaac tgtgttgcgt gaacaagcta agtaattatg gaaggaggcc attaagcgta
    31441 tgactgaagg aagaaatcaa cgcaaagttt atcaaggtcg cgtggtttca gacaaaatgg
    31501 ataaaacaat taccgttgct gtcgaaacaa agaaaaacca ccctatctat ggcaaacgca
    31561 tgaactattc taagaaatac aaagtgcatg atgaaaacaa cacagcaaaa gttggcgaca
    31621 tcgtgagaat tatggaaact cgtccattat cagctacaaa acgtttccgt ttgttggaag
    31681 tagtcgaaga agcagttatt atctaataac acgagatttt cctatataga ttgaatgcaa
    31741 aatctgaaag gaggatacac aacgtgatcc aagcagaaag tcgtttaaaa gtcgctgata
    31801 actcaggcgc acgtgaaatt ttgacgatca aagtccttgg tggatctggt cgtaaaactg
    31861 ctaacatcgg tgatgtgatc gttgctacgg ttaaacaagc aacgccaggt ggggttgtca
    31921 aaaaaggtga cgtcgttaaa gccgttatcg ttcgaacaaa atcaggagct cgtcgtacag
    31981 acggttcata tattaaattt gatgaaaatg ctgcagtgat tattcgtgat gataaaagcc
    32041 ctcgtggaac acgtatcttt gggccagttg cacgtgaact acgtgaaaac aacttcatga
    32101 agatcgtttc actagcacca gaagttttat aatcttgaga cacttatcaa aggaggtgcg
    32161 aaacagttat gtttgttaaa aaaggcgata aagttaaagt tatcactgga aaagacaaaa
    32221 acaaagaagg cgttgtacta gcagcgttcc cgaaaaaaga taaagttatt gtcgaaggtg
    32281 taaatgtcgt taaaaaacac caaaaacctt ctcaagctgc tcctcaaggt ggaattgttg
    32341 agatggaagc gccaattcat gtttctaacg tgatggtggt tgactctact ggtgtagctg
    32401 gccgagttgg ctacaaagaa gtagacggca aaaaagtccg tgtttctaaa aaaaccggtg
    32461 aagttttaga taaataaaag tttaaggaag gagggtctta ctgaatgaac cgcctaaaag
    32521 aaaaatatct taaagaagta actccatcat tgatggaaaa atttaactat agctctgtta
    32581 tgcaaacacc taaagttgaa aaaatcgtca tcaacatggg tgttggtgat gcggtatcaa
    32641 acgctaaaaa cttagataaa gcagttgaag aattaacttt gatcactggt caaaaaccaa
    32701 tgattacaaa agctaaaaaa tcaatcgctg gattccgttt acgtgaagga atgccaattg
    32761 gtgcaaaagt tacattgcgc ggagaaagaa tgtacgaatt cttagacaaa ttggtttctg
    32821 tttcactacc acgtgtacgt gacttccatg gtgtaagtaa aaaagccttt gacggtcgtg
    32881 gaaactatac tttaggtatt aaagaacaat tgattttccc agaagtagat tatgatttag
    32941 tagataaagt acgtggtatg gacatcgtta ttgtaacaac agcaaactct gatgaagaat
    33001 ctcgtgagtt gttgacacaa ttaggcatgc cattccaaaa ataattaaag gaggcgaact
    33061 acgtggctaa aaaatcaatg attgctaaaa acaaacgtcc tgcaaaattt tcaacacaag
    33121 cttatactcg ttgcgaacgt tgcggacgtc cacattcagt ttatcgtaag ttccatcttt
    33181 gccgtatttg cttccgcgaa cttgcctata aaggtcaaat tcccggcgtg aagaaagcta
    33241 gctggtaaaa agtaaattcg cataagaagg aggtaaaaga tcaatggtca tgacagatcc
    33301 aattgcagat tttctaactc gtatccgtaa cgcaaacatg gttaaacatg agtctttaga
    33361 agtacctgca tcaaaaatta aacgtgacat cgctgaaatc ttgaaacgtg aaggtttcgt
    33421 tcgtgatgtt gaatacatcg aagatgacaa acaaggcgtg atccgtgttt tcctaaaatt
    33481 tggtaaaaac ggcgaacgtg ttatcacaaa cttaaaacgt atctctaaac caggtttgcg
    33541 tgcttatgtc aaagctgacg aagtaccaaa agtattgaac ggtttaggta tcgcaatcat
    33601 ttcgacttct gaaggtgttg tcactgataa agaagctcgt gaaaaaaata tcggcggcga
    33661 agttatcgct tacgtatggt aatcaagtag aatctacaag gaggtgtctt taagtgagcc
    33721 gtatcggaaa taaagtcgtt gttatccctg aaggagtaac agttactcaa gacggaaaca
    33781 acgttacagt taaaggacca aaaggtgaat tgactcgtac tttttcagca gatatcaaaa
    33841 tgaatatcga aggaaacgaa gtaactttca ctcgtccaaa cgacagtaaa gaaatgaaaa
    33901 caattcatgg aacaactcgt gcgaacttca acaacatggt tgtaggtgtc agcgaaggtt
    33961 tccaaaaagc gttagaacta atcggggttg ggtaccgtgc acaattacaa ggatcaaaac
    34021 ttgtattgaa cgttggttac tcacatccag tagaaatcac accaccagct ggagtaactg
    34081 ttgaagtacc agctaacaca caagtaattg ttaaaggtgc gaacaaagaa gaagttggcg
    34141 aattagctgc aaacattcgt ggaactcgtc ctccagaacc ttataaaggt aaaggtattc
    34201 gttatgttgg cgaatatgta cgccgtaaag aaggtaaaac tggtaaataa tcgtttagaa
    34261 aaattgcata gaagccagca gcaggaaaaa ggcatttggc tgaagtttac cttcaaaaaa
    34321 atacattttt acttgtgccg cagcttctat ttttcgaaac gtatttactg cttgaaatag
    34381 tagtacaata aaaataaaga ggtgacaatt gtgattacaa aaccagataa gaacaaaaca
    34441 cgtcaaaaga gacatcgtcg tgtacgtaac aatatctctg gtactgctga gcgcccacgc
    34501 ttgaacgttt ttcgttctaa caaaaacatc tacgctcaaa ttattgatga cgtagcgggt
    34561 gtaacgctag caagtgcctc taccttggat aaagaaattt caggtggaac aaaaacagaa
    34621 gcagcacaag ctgtcggtaa actagttgct gaacgtgcag ctgaaaaagg cattaaagta
    34681 gtagtctttg accgtggtgg atacctttac catggccgtg tgcaagcttt agctgaagct
    34741 gctcgcgaaa atggactaga attttagaag aaggaggaat accattcatg gtttatatcg
    34801 atccaaaaca tttggaatta gaagaccgcg ttgttgcaat taaccgtgta acaaaagttg
    34861 ttaaaggtgg acgtcgtcta cgttttgctg ctttagttgt tgtcggtgac aaaaacggac
    34921 acgtagggtt tggtacaggt aaagctcaag aagttcctga agcaatccgt aaagcaattg
    34981 aagatgcgaa gaaaaactta gttgaagtac ctatggttgg ttcaacaatc ccacacgaag
    35041 taatcggtgc ttttagtggt ggtagaatcc taatgaaacc tgctgtagaa ggttctgggg
    35101 ttgctgctgg tggaccagtt cgtgccgtat tagaattagc tggggtagca gatatcactt
    35161 ctaaatcttt aggctcaaat acaccaatca acgttgttcg cgcaacagtt gaaggtttga
    35221 aacaattgaa acgtgcagaa gaagttgcag aacttcgcgg caaatcagtt gaagaattaa
    35281 tcggataagg aggacaacaa taatggctga attaaaagtt actttaaaac gcagtattat
    35341 cggacgtcct caaaaccaac gcgatacagt taaagcgtta ggtcttacaa agattaacag
    35401 ttcagtggtt aagccttcta atgaagcaat taaaggcatg atcaatactg tttctcacct
    35461 agtggacgtt gaagaaattt aatttagaaa aatcataact agaacattaa ggaggtgcca
    35521 aacctatgaa acttcatgaa ttaaaacctg ctgaaggttc acgccaagta cgtaaccgtg
    35581 ttggtcgtgg tacttcatct ggtaacggaa aaactgccgg acgcggacaa aaaggacaaa
    35641 aagctcgttc aggcggcggt gtgcgtttag gatttgaagg gggacaaaca ccattgttcc
    35701 gtcgtttacc aaaacgagga ttcacaaacg tgaaccgtaa agactatgca gtcattaatc
    35761 ttgatgtatt gaaccgcttt gaagacggag ctgaagtaac tcctgttgct ttagttgaag
    35821 ctggaatcgt gaaaaacgaa aaagctggaa tcaaagtatt agctaatggg gaactaaaca
    35881 agaaattaac tgtgaaagca gcaaaattct ctaaagcagc tcaagaagca attgaagcgg
    35941 ctggtggatc aatcgaggtg atctaatgtt tagactatta aaagatgctt ttaaagtaaa
    36001 agacattaga tcgaaaatcc tatttactgt atttgtgttg tttgtatttc gcctaggtgc
    36061 acatattact gtaccaggcg taaatgctgc ttcattgcaa aacctttctt ctttgccatt
    36121 tttcaacatg ttgaacttgg taagtggtag tgcgatgcaa aacttttcca ttttctcaat
    36181 gggggtttca ccatacatta ctgcttctat cgtcattcag cttcttcaaa tggacatcgt
    36241 gcctcgattt gttgaatggt cgaaacaagg ggaagttggt cgtaaaaaac tgaatcaagc
    36301 gactcgatat ctgacattag tattggcatt tatccaatct gtcggtatca ctgctggatt
    36361 caatcaatac gctcaattag gtttcgtgaa taatcctaac gtagcaactt acgtaacgat
    36421 cggtttgatt ctaacagccg gtacgatgtt tgttacttgg ctaggagaac agatcacaga
    36481 aaaaggtatc ggaaatggcg tatcaatgat catttttgca ggtatcattt ctagattgcc
    36541 tgaaagtatc agagaaattt atgaagatta ctttataaat attgatcctt cagacatatg
    36601 gaaatctgct atttttgtgg ccattttact agtagcggtc ttgttgatcg tgacattcgt
    36661 aacatttttc caacaagctg aacgcaagat cccgatccaa tatacgaaac gcgtagctgg
    36721 cgcgcctaca agcagctatc tgccgttgaa agtaaatgca gctggagtta ttccagttat
    36781 ctttgctagt tcgtttattg ctacgccaaa tgctgtttta caagcattga gcggtagatt
    36841 cggttctgaa aactggtaca aagtgatgat ggagatcttt aactataata cagcacctgg
    36901 tgctacgatt tatacgattc tgatcgttgc cttcactttc ttctacgcct ttgttcaagt
    36961 aaaccctgag aaattagcgg aaaacttgca aaagcaagga agttatatac caagcgtacg
    37021 ccctggtaag gggactgaag agtatgtctc aagattactg atgcgtttaa gtacagttgg
    37081 tgcagtcttc cttggtttag tggcattgct tccaatcatt gctcaaatgg tttgggatct
    37141 tccacaatca atcggattag gcggtacaag cttactgatc gttatcggtg tagctttaga
    37201 aactgcgaaa cagttagaag gcttaatgct gaaacgtaaa tatgttggat tcattgagta
    37261 agaaagcgtg ttgaggtttc ccctcaacac acgttctcac acatttatta ggagggaaaa
    37321 caatgaacct cattttaatg gggctgccag gcgcaggtaa aggaacacaa gctgaaaaaa
    37381 tcattgatgc ttatggtatt ccgcacatct caacaggaga tatgttccgc gcagcgatgc
    37441 aaaacgaaac agctcttggc ctggaagcaa agtcttatat ggataaaggt gcattagttc
    37501 ctgatgaagt aacaaatgga atcgtgaaag agcgactagc tgaaccagat acagagaaag
    37561 gcttcttatt agatggcttt ccacgtacgc tagatcaagc aaaagctctg gacgcaatgc
    37621 taaaagattt gaataaaaaa attgatgctg tcatcgatat ccatgttggt gaagaaatct
    37681 tggtcgaacg tctagccggc cgatttatct gcagcaattg tggagcaact taccataaaa
    37741 ttttcaaccc tacaaaagtt gaagacacat gtgatcgttg cggtgggcat gaattctatc
    37801 aaagagaaga tgataaacct gagacggtta aaaatcgtct ggctatcaac atcaaaaata
    37861 gtgaaccaat cttggcttat tataaagaac aaggtttgct aaacactatt gatggtgctc
    37921 gtgaaatcga tgctgtattt gcagatgtac aaaaaatcat tgaaaaatag cacgattgcc
    37981 cgtagccgac ttgcattatg cagttactct tgtcaagttc aataaattat gatagaatat
    38041 gtcagtccga cttctagaga atcctctaga tgatccattt tgagaatttt gaggtgggaa
    38101 ctgcagtttc cgccatttta tcgtgtgaaa atgcgaaaca agtacaagga ggtactgtgc
    38161 gtggcaaaag aagatatgat tgaagtcgaa ggtacagtcg tcgaaacttt gccgaatgca
    38221 atgtttaaag ttgaactaga aaacggacac caagttcttg ctactgtttc aggtaaaatt
    38281 cgtatgcatt acatccgtat cttacctggt gacaaagtaa cggttgaatt gtctccatac
    38341 gatcttaacc gtggccgtat tacttatcgc tttaaataat tgtactccgt aaaactacag
    38401 gaggtattat catgaaagta agaccatcag taaaaccaat gtgcgaacat tgtaaagtaa
    38461 ttcgtcgtaa aggacgcgtt atggtgattt gcccagcaaa tccaaaacat aaacaacgtc
    38521 aaggataatt ggaggtgcta taaatatggc tcgtattgca ggagtagata ttcctcgtga
    38581 taaacgtgta gtagtttcac ttacttatat ctatggtatt ggtaacacta ctgctaaaaa
    38641 gatcttagct gatgctggtg tatctgaaga tgttcgcgtt cgtgaattaa cgaatgaaca
    38701 aacagatgct atccgtgcag aagtagataa attaaaagtt gaaggggatc ttcgtcgtga
    38761 agtgaacttg aacatcaaac gtttgatgga aatcggttct taccgtggaa tccgtcatcg
    38821 ccgtggattg cctgttcgtg gacaaaacac gaaaaacaat gcacgtactc gtaaaggccc
    38881 agctcgcgct atcgctggca agaaaaaata attcttaagt gaaggaggtt aaaacttcat
    38941 ggcagcaaaa aaagtgaatc gtaaacgccg tgtgaagaag aatatagaag caggtattgc
    39001 acatatccat tctacattca ataacactat catcatgatc actgatactc acggaaatgc
    39061 attagcgtgg tcatcagctg gttcattagg tttcaaagga agcaaaaaat caactccttt
    39121 tgccgctcaa atggcagcag aaactgctac aaaagcagca atggaacacg gattaaagac
    39181 tgttgaagta acagttaaag gacctggttc tggacgtgaa gcagcaattc gttcattaca
    39241 agctacaggt ttagaagtga ctgcaattcg tgacgtgact ccagttcctc ataatggtgc
    39301 ccgccctcca aaacgccgtc gtgtttaatg agtgccgctc attttgagtt ttatcagtaa
    39361 cgtcattgaa caagacactt ttcgttttga aaggggtaaa gataagaatg attgagttcg
    39421 aaaaaccaag aatcgcaaaa attgatgaag aaaaagatta tggcaagttc atcgttgaac
    39481 ctcttgaaag agggtatggg actactttag ggaattccct acgtcgtatt ttattatctt
    39541 ctttgccagg tgctgccatc actaatattc aaatcgatgg tgtactgcat gaattctcta
    39601 ccatcaaagg tgttagagaa gacgtcactc aaatcatctt gaacattaaa ggcttagcgc
    39661 tgaaaatgta tggccaagaa gaaaaaaccc ttgaaatcga tattaccgga cctgctacag
    39721 taactgctgg cgatattatc gttgatagtg atgtagaaat tcttaacaaa gatatgtaca
    39781 tctgtagtgt ctctgaagga gctacgttcc atgctcgctt aacagtgaaa cctggacgtg
    39841 gttatgttca agcagatgaa aataaaaaag aagatatgcc aattggcgtt cttccagtcg
    39901 attcaatcta cacacctgtt cgtcgtgtga actatcaagt tgagaacaca cgtgttggac
    39961 accgtgaaga ttttgataaa ttgacgatgg agatttggac agatggttca attgaaccgt
    40021 tggaagcaat gagtttgtct gcgaaaatca tgactgaaca tttggatatt tttgtgaact
    40081 taactgatga agcaaaaaat gctgaaatca tggtcgaaaa agaagaaaca caaaaagaaa
    40141 aaatgttgga aatgacgatc gaagagttag acttgtctgt tcgctcttac aattgtttga
    40201 aacgtgcagg aatcaatact gtacaagaac ttacaaataa atctgagcct gaaatgatca
    40261 aagtccgtaa cttaggacgt aaatcattag aagaagttaa agcaaaattg cacgacttag
    40321 gtttaggttt acgtaaagaa gattaaaacc ttttacgaag gagggaaacc aacgtgagtt
    40381 atcgtaaact aggacgcaca tctagccaac gtaaagcgat gttgcgtgat ttaacaactg
    40441 atttattaat caacgaacgt attgtgacta ctgaagctcg tgcgaaagaa gttcgctcaa
    40501 ctgcagaaaa aatgatcact ttaggtaaac gcggagattt gcatgcacgt cgtcaagctg
    40561 cggctttcgt acgtaatgaa gttgccagcg tgcgtgaaga aaatgaggac atcgtcattg
    40621 aatcagcttt acaaaaactg ttcaacgata ttgcacctcg ttacgcagaa cgtcaaggcg
    40681 gatacacacg cattttgaag acagaaccaa gacgcggtga tggtgcacca atggttgtct
    40741 tagaacttgt ctaaaatcac actaataaca tcactttata gatgattctt ttagagtgtt
    40801 atgatgttgg aagatatttt tccgagtcta gctcagcgct gctcctcaag cgaatatcgc
    40861 ttggggagta agcactcatc ataaagtgtt tttttatacc ttcaattacc tgtcatgaca
    40921 gatatgtttg aaggcataaa aaaacatttt aagcgagaaa taattgaaaa ttttgtcttt
    40981 ttttgatagt gttagtagga actttaggat gaagaaggag taatcatgga gccaattatt
    41041 gaattagaaa agataaatta taaataccag ccagatgatc ttcgccccgc attgaaagat
    41101 gtctccttta caattgataa aggtgagtgg atcgctatta ttggacacaa tggttcagga
    41161 aaatcgacac ttgccaaaac gatcaatgga ttgcttctgc cagaatcagg gatcgtgaaa
    41221 gtgggaaatc aaatattgga tgaagaaaat atttggacga tccgacagat ggttggaatg
    41281 atttttcaaa atccagacaa tcagtttgtt ggttcgacag tagaagatga cgttgctttt
    41341 ggtcttgaaa atcaagggat tcccagagaa gaaatgctag tgcgtgtgaa agatgcactt
    41401 gagaaagtta gaatggctga gtttgcttca cgcgagcctg ctcgtttatc aggagggcaa
    41461 aaacaacgtg ttgccattgc cggcgtggtt gccttacgac ctgatatcat tattttagat
    41521 gaagcaacca gtatgctaga tccagaaggt cgtgaagaag tgatctctac gatcaagaag
    41581 atcaaagaag aaagtcaatt gaccgttata tctatcactc atgatattga tgaagcagct
    41641 aatgccaatc ggatactagt gatgagacaa ggcgaacttg tccgtgaagg tacaccaaaa
    41701 gaaatttttt ctgctggtcc tgaactgatc gacttaggtc tagatctacc atttcctgaa
    41761 aaactgaaga gcgcactgaa agaacgtggg gttgatgtgc ccagtgaata tatgacagaa
    41821 gaaaggatgg tggattggtt atggacatcc gttttgaaca agtagacttc acttatcagc
    41881 cgaatacacc atttgaacaa agagccttat ttgacatcaa tatgacgatc aaagaaaaca
    41941 gttatactgc attagtaggg cataccggaa gcgggaaatc aaccttactt cagcatttga
    42001 atgcgcttgt taagccaaca agcggtacag tccatattgg agaacgagat attcagccgg
    42061 atacggataa taagaattta aagcccatcc gaaaaaaagt tggcatcgtc tttcagtttc
    42121 cagaagcaca gctattcgaa gaaacggtag caaaagacat tgctttcggt cctaaaaact
    42181 ttggtgtcag cgaagaagaa gcactagtcc tagcaaaaga aacattagaa caagttgggc
    42241 tggatgaaag ctatttggaa cgttcgccat ttgaactttc aggagggcaa atgcgtagag
    42301 tagcaatcgc tggtgtgctt gccatgaggc cggaagtact tgtattggat gaaccaacgg
    42361 caggacttga tccccagggc agaaaagaaa tgatggagat gttttggcgt cttcataagg
    42421 aacagcagat cactattgta ttagttacgc atttaatgga tgatgtagcc aattttgcag
    42481 attatgtcta tgtgttggaa aagggacgaa tcgttaatag cggggagccg caagaggtct
    42541 ttcaaaacat tgaatggcta aaagaaaaac aactaggcgt acctactgcc accgagtttg
    42601 cagaagaatt aatggctaaa gggatgaact ttgctacctt gcctttgaca gctgaagaat
    42661 tagcagacgc tatcgtccat tatgctggag gaaatgccca tgatgaataa attgatattt
    42721 ggtcgttata tgcctggaga ttccttgatc catcgattgg atccccgagc taaattatta
    42781 gccagttttt attttatcgg aatcattttt ttagcaaata attgggaaac gtaccttttg
    42841 ttggcatttt tcacattact ttctgtcttc ttgtcaaaag tagatttgaa attttttatc
    42901 cgaggcattc gcccattgat ctggctaatc ctcttcactg tagctttgca ggtcttgttt
    42961 acaagtggcg gagaaactta ttggagttgg ggtgttttcc atatcactga atttggtgtg
    43021 atgaacggcc tctttatttt ctgtcgattc gtgttgatca tttttatgtc gactctactc
    43081 acgcttacta caccgccttt ggaattatcg gatgcgattg agtacttgct tcgtccattg
    43141 aaagccgtac ggttcccagt ccacgaaatt tcattgatgc tgtcgattgc tcttcgtttt
    43201 gtgcctacat tgatggacga aacagaaaag atcatgaacg ctcagcgcgc tcgcggtgtt
    43261 gattttggtg aaggaaacct agttcagaaa atgaaagcag tcattccttt gctgattcct
    43321 ttatttgtca gcagcttcaa ccgtgcggaa gatcttgcga ctgctatgga agcaagaggc
    43381 tacaaaggtg gggaaggaag aacgaaatat cgtgtattgc attggcataa tagagacacg
    43441 atggttatca ttgcttttgt attattaact gtgctactga tctttttaag aggataaacg
    43501 ttcagtgggc cgctatctat tcttttcttg ctgatctgtt tgcaagaaag gatgcaagca
    43561 gtgtatgaca agaaatatta gggtctgtgg cagactaagg tcacaggcct ctttctttta
    43621 tctgaaaaga aagaacgaaa aaattttata gaaaaatcat tattccagat aaccttttag
    43681 gaacaaagga gagaaaaaca tggtacgtta caaagcaatc attgcgtacg acggaacaaa
    43741 ttttaatgga ttccaaaaac agccaaatgg gcgtactgtt caagaagaag tagaaaaaac
    43801 attacaaaaa atggcaaatg gaaaagaaat cacggtcttt ggttcgggaa ggacagatgc
    43861 cggagtacat gcgatcgggc aagtaatcca ttttgattat ccagaggagc gtccgttaga
    43921 acgaatgcgt ttcgcgctag atacccagtc accagaggat attgctgtaa gacaagtaga
    43981 aattgtttca gaagacttcc acgcaagata tttggtcaaa gaaaagacgt atcaatttcg
    44041 agtggatata gggaaaccac gcagtccttt tcgacgccat tatgcaagtt attttcctta
    44101 cccacttgat ttggaaaaaa ttcagcgggc gcttcctgat ttattaggga ctcacgattt
    44161 cacctctttt tgtgcatcag gaagctcgat agaggataaa atacgtacga tctacgaggc
    44221 taagatggag gtaaatgaaa caaaagacga attgttgttt acatttaggg gaaatggctt
    44281 cttgtataag atgatacgga tcttagtagg aacgcttttg aaaattggca atggccgatt
    44341 gcctgaagat agtatcccag atattattgc gaaaaaagat cgtaatgcag caggacctac
    44401 agcacaccct gaaggacttt atttgtatga agtgaaatat gaataagagg ttatgataga
    44461 agtggtcagc ttcaagaaat aagaaggtat ttacgaaaat tacttctcaa aattttgcaa
    44521 aatttcggct tattttcgaa gaagctactt ctggaacacc gtttaagaaa gaggtcgtga
    44581 gcctgtcatt taactctgag tcacaaagag caatttcaaa aaacagcttc tcatctttga
    44641 tgaatatcgt gacttgtgga cgaggcgttg ataagtgaat catctttttg ttacctattt
    44701 tttctgtaac caaaaaacga tggaacgttg ttttgattgc ccttggtgcg gacagtctga
    44761 acaggttcca tcgtttcttt attttctacg tcttcttctg tgtgtgtttc gtggttgttc
    44821 ttctattgct ggatcaatcg tgccataaaa ggggcgattg cggtcaaggt accagacata
    44881 aagaataaac aatgcaatac ataggacaaa aaggattgca cctatcgtaa atccttcagg
    44941 caagtaactg aaagtgacag tatgtttacc tgctggaact tttatcatca agaatgcgtc
    45001 tttgaaattg ctgaccttga ctggtttccc atcaatttta gctttccatc ctttgtcata
    45061 aggaatagtt gtcaccaaca tggaatcttc agcggtattt acagtcccag aagcttttct
    45121 gccagtggct tccatttcga cacctttttc tttgatctga ttcattgcgg cttgataggc
    45181 tacaacatct agaccaacga ctttaggctc catgaaactt atttctttcg tcccataaaa
    45241 acttgcagta aatgtcactg ttgtctcttg aggataatag ccaagatcat agtattgacc
    45301 agaaatgttg atttgcgttt ttcgcgatgt accattgaca gtgatcgtcg cactagaact
    45361 ttctaattgc gcaaaattgg ttgggaacaa acttaagtaa gcttgtgtat ttgcaggcac
    45421 atggacttcc caagtgagct cttttggctg gttatctgct gtttctgagt aagtgacgcc
    45481 agtcgttgtc tttgtgatcg tcgtattcaa ctgattcttc aaagtaggtg tatagaatgt
    45541 aaaatactgt tcatttagac cagacaatgt attgatcaag tttgtctgac tggtcaaatt
    45601 atctgtcact ggctgctcaa catcattaac ggacaacggt gcagtaaatg ctagtggcaa
    45661 tgcattgaca ttctgataca gtgtatagtc gccgctttga ccagcttggc ggaagccata
    45721 tttactgaac gtgctttcgt ttttagaaat gttatatttg attcctgtaa acccatccat
    45781 cagcaaagta ttattgttat aacggatatt caaatttgtc cctcttgaac ggaaacctaa
    45841 tttatccagg taagaggaag aattacgatt tcttatagaa gaaaacaaac tgataccact
    45901 gtaaccatag ttgatcgaat cgtttgcaga tactggatcc agattttcca agcggtaaaa
    45961 cgagtcggaa tctttttttg tttcatttac aagagctttc aagtcaggat aaggatcagt
    46021 atataaactg cgggaagcat aattccaatc atcaagaatg ccatggatca tactgttcgt
    46081 attgaccagt gcttcagcag acatgatcaa taataacaat atactcagat gattgaatga
    46141 aagtttttta tgctgataaa atcccacagc aaaagcataa atccctaaga aaaccactgt
    46201 caatacaaag gaagtcatcg tcacataggt gtagcttcct tcaggtttga tgccccatgc
    46261 caccgcaaag agagcagcta cgaccaaaat gattcctaac aacagcccac catcgtcttg
    46321 ttctatcttt tcccatcctt ttcctgcaag caggagcact aagaaagaga acagataggc
    46381 ataacggaat aaaaacatat tcggtgcatg cataccatgc cagaacaaat tcaatggaac
    46441 aagataaaaa cttgcgataa gtatggcgaa aagactgccg tacaaaaatt tatttttcaa
    46501 cggtactttc cgactggcaa aataaaacag acagaggact aatggtagca gacctgcgta
    46561 aacgaacgga atcgatccgt attttgtcgt gtcataaaca ccaatcatat ttttcatgat
    46621 tagatccaga taagaagtcg cttctgtttt caacgtagtg atctgactca gtgcctcgcc
    46681 atttgaccga agatccagca ctgctggcaa tacaatgatc attgaagcgc cgcctgccag
    46741 taaagaagtg ataccataag gaacaatcgt ttttttatat tctgaccagt ttgtcaatag
    46801 acgggcgata aaatataaga aagaaaatac gccaatcata aaacccatat aaaaactgga
    46861 taaaaacaag agtaaataac tgataaataa aagtttcggc cgtttaagat ccataacacg
    46921 atgaatcccc aaaatcacta atggaagata aacaaatgca tccagccaca tgatgatctc
    46981 cgaatgtgca gtgataaatg agatcaatgc gtaactgacg ctaagtgcaa catgccccca
    47041 gcgaggaatc ttgaacgtac gtgcaagaaa ccaaaaagcc aatccggcac agccgacctt
    47101 aagcaaagtc agaacataca gtgcatctgg catcatctgg tttggaaaaa agaacaccag
    47161 tggcgtgaag atcccgccta gatagtaaga aattaaagat aaataattca atcctagaga
    47221 agcattccat gtataaaaaa tactttgctt tccaagaaga acatttcgga agctggcatg
    47281 aaaattagaa aactgtgaaa aggcatcact tgccaaaata cttctgctgc ttccaggata
    47341 gattccgata cttagataaa caagtgctaa aatcaaaaac ggaatcagga aactagctgc
    47401 tgcgtagcgt ccgttttctc taaagaatga ctttaaattt tttttcatat ttattttcca
    47461 ccaaatttct atgaagttgt attcagttta tcatatcctt gtttttctct gcttaaaaag
    47521 agtctagttt tcacaaaaaa ataaaattta gaataaataa cttcataatt tgttcgtata
    47581 acaaaaataa acgcaaaaaa agggtaggaa tcaaaagtcc cacccttaaa aatttttatt
//
LOCUS       DADVXM010000013        45033 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.014, whole genome shotgun sequence.
ACCESSION   DADVXM010000013 DADVXM010000000
VERSION     DADVXM010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 45033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45033
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.014"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            201..1097
                     /locus_tag="KB927_000836"
     CDS             201..1097
                     /locus_tag="KB927_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6839771.1"
                     /translation="MEINLFEAGNRIKQIREKHGYTMADLGKLVDANSPSTINNWEKG
                     NNLPNRKRLEKIALLGGTSVEWIKYGDFSDYVYRLTQNIEEKILKEYGETTLNNYREA
                     LLDELTIEKITYEEDTKILAAAEKINTQNIFQEVKYMYSPDEDYRNIEVKPDLGLTDD
                     NKNIKMIGQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAE
                     IGGVSELYLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKID
                     DPDKREISLNAICQLSLLDKMG"
     gene            1146..2117
                     /locus_tag="KB927_000837"
     CDS             1146..2117
                     /locus_tag="KB927_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6839772.1"
                     /translation="MKPNLSLTSERIRKIIESKGLTLERFGDLIGDTPISSVNNWLRG
                     VSLPNKNRLLTIANIGNTSVDWIKWGTLEEYIASYLIDSGYELYIKDFPEIPYKVFKD
                     IQEKYSDTFSLDKDYELLNPIIKFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTT
                     LTNYYRGERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDK
                     IVKNIASLDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQ
                     KKFINKALNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            2172..3338
                     /locus_tag="KB927_000838"
     CDS             2172..3338
                     /locus_tag="KB927_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6839773.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            complement(3427..3819)
                     /gene="rpsI"
                     /locus_tag="KB927_000839"
     CDS             complement(3427..3819)
                     /gene="rpsI"
                     /locus_tag="KB927_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBB6839774.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(3835..4278)
                     /gene="rplM"
                     /locus_tag="KB927_000840"
     CDS             complement(3835..4278)
                     /gene="rplM"
                     /locus_tag="KB927_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBB6839775.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(4797..5264)
                     /locus_tag="KB927_000841"
     CDS             complement(4797..5264)
                     /locus_tag="KB927_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBB6839776.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(5384..6922)
                     /locus_tag="KB927_000842"
     CDS             complement(5384..6922)
                     /locus_tag="KB927_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBB6839777.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            7002..7688
                     /locus_tag="KB927_000843"
     CDS             7002..7688
                     /locus_tag="KB927_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBB6839778.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(7889..8416)
                     /gene="msrA"
                     /locus_tag="KB927_000844"
     CDS             complement(7889..8416)
                     /gene="msrA"
                     /locus_tag="KB927_000844"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6839779.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(8500..9177)
                     /gene="pgmB"
                     /locus_tag="KB927_000845"
     CDS             complement(8500..9177)
                     /gene="pgmB"
                     /locus_tag="KB927_000845"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBB6839780.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(9174..10304)
                     /locus_tag="KB927_000846"
     CDS             complement(9174..10304)
                     /locus_tag="KB927_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6839781.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(10304..12487)
                     /locus_tag="KB927_000847"
     CDS             complement(10304..12487)
                     /locus_tag="KB927_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBB6839782.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(12484..13509)
                     /locus_tag="KB927_000848"
     CDS             complement(12484..13509)
                     /locus_tag="KB927_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6839783.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(13554..14381)
                     /locus_tag="KB927_000849"
     CDS             complement(13554..14381)
                     /locus_tag="KB927_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6839784.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(14378..15445)
                     /locus_tag="KB927_000850"
     CDS             complement(14378..15445)
                     /locus_tag="KB927_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBB6839785.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(15471..16307)
                     /locus_tag="KB927_000851"
     CDS             complement(15471..16307)
                     /locus_tag="KB927_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6839786.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(16304..17173)
                     /locus_tag="KB927_000852"
     CDS             complement(16304..17173)
                     /locus_tag="KB927_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6839787.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(17243..18526)
                     /locus_tag="KB927_000853"
     CDS             complement(17243..18526)
                     /locus_tag="KB927_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBB6839788.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(18540..20225)
                     /locus_tag="KB927_000854"
     CDS             complement(18540..20225)
                     /locus_tag="KB927_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBB6839789.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            20500..21525
                     /locus_tag="KB927_000855"
     CDS             20500..21525
                     /locus_tag="KB927_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6839790.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(22120..25794)
                     /gene="rpoC"
                     /locus_tag="KB927_000856"
     CDS             complement(22120..25794)
                     /gene="rpoC"
                     /locus_tag="KB927_000856"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBB6839791.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(25852..29469)
                     /gene="rpoB"
                     /locus_tag="KB927_000857"
     CDS             complement(25852..29469)
                     /gene="rpoB"
                     /locus_tag="KB927_000857"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBB6839792.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            30197..31165
                     /locus_tag="KB927_000858"
     CDS             30197..31165
                     /locus_tag="KB927_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6839793.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            31183..32088
                     /locus_tag="KB927_000859"
     CDS             31183..32088
                     /locus_tag="KB927_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6839794.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            32085..32891
                     /locus_tag="KB927_000860"
     CDS             32085..32891
                     /locus_tag="KB927_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6839795.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            33027..34016
                     /locus_tag="KB927_000861"
     CDS             33027..34016
                     /locus_tag="KB927_000861"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBB6839796.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(34333..34857)
                     /locus_tag="KB927_000862"
     CDS             complement(34333..34857)
                     /locus_tag="KB927_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBB6839797.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            35144..36955
                     /gene="scm"
                     /locus_tag="KB927_000863"
     CDS             35144..36955
                     /gene="scm"
                     /locus_tag="KB927_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBB6839798.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSS
                     TTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKR
                     ALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(37110..38096)
                     /locus_tag="KB927_000864"
     CDS             complement(37110..38096)
                     /locus_tag="KB927_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBB6839799.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(38119..38685)
                     /locus_tag="KB927_000865"
     CDS             complement(38119..38685)
                     /locus_tag="KB927_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBB6839800.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(38699..39115)
                     /locus_tag="KB927_000866"
     CDS             complement(38699..39115)
                     /locus_tag="KB927_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBB6839801.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(39572..41506)
                     /locus_tag="KB927_000867"
     CDS             complement(39572..41506)
                     /locus_tag="KB927_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6839802.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            41787..42743
                     /locus_tag="KB927_000868"
     CDS             41787..42743
                     /locus_tag="KB927_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBB6839803.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            42833..43936
                     /locus_tag="KB927_000869"
     CDS             42833..43936
                     /locus_tag="KB927_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBB6839804.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            43949..44902
                     /gene="menA"
                     /locus_tag="KB927_000870"
     CDS             43949..44902
                     /gene="menA"
                     /locus_tag="KB927_000870"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBB6839805.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
BASE COUNT        13247 a         9402 c         8477 g        13907 t
ORIGIN      
        1 ggttgaattg atagatggac tcaaagaaga aaattcaaag ttaaaagaga agataaaata
       61 ctatgaatgt ttatttgatg gtatagagag tctgctgaac tcacgaaaaa atccctagtt
      121 tttatgaatg accgttttgt aaatctgatt gaaatagatt tatatgattt cggtatatga
      181 tatacattag gaggtgtcga atggaaataa atctttttga ggctggtaat cgaataaagc
      241 aaatacgaga aaaacatgga tatactatgg cagacttagg taaactggtt gatgccaata
      301 gtcctagcac aattaacaat tgggaaaagg gaaataactt acctaataga aagcgtcttg
      361 aaaaaattgc actattaggt ggtacttctg ttgaatggat aaagtatgga gatttttccg
      421 attatgttta tcgcttgaca caaaatatag aggaaaaaat tcttaaagag tacggagaga
      481 ctacactgaa caactaccgt gaagctcttc tagatgaact tacgattgaa aaaatcacat
      541 acgaagaaga tacaaagata ttagcagctg ccgaaaaaat caatacacaa aatatttttc
      601 aggaggtgaa gtacatgtat tctcctgatg aagattatcg aaatatagaa gtcaaaccag
      661 atttaggact gactgatgac aacaaaaata ttaaaatgat tggacaacgt ataaggaaaa
      721 taagaaaaaa agagaatatt acattagaag aattcggcaa actattctct cctacagctg
      781 ataaagctgt tataagcaac tgggaaaatg gtaaaaacct tcctaactca gaaagaatta
      841 aaaagattgc agaaattggc ggagtttctg aactttatct tatgacgggt gtcgattcaa
      901 gcgtagcaga atcaatgtat tttctatctg aagtagcatt ggatgctttg gaacgtctgt
      961 caattgagga agtcaataga ataattgaaa gcttcgccgg ttatcttaat gtgatttcaa
     1021 aaattgatga tccagataag cgagaaatat ctctcaatgc tatttgtcaa ctatcacttc
     1081 tcgataaaat gggttgattc acaaaaaata ttgaaagatt actttactca cgaggaggct
     1141 tagctatgaa acctaatcta tcgttaacta gtgaacgtat tagaaaaatt atcgaatcca
     1201 aaggtctgac attagaacga ttcggtgatt taattggcga cacaccaata agttctgtta
     1261 ataattggct tagaggcgtg tctttaccca ataaaaatag gcttttaaca attgcaaata
     1321 ttggaaacac tagtgtagac tggattaaat ggggaacttt ggaagaatac atagcttcat
     1381 accttataga ttcaggttat gagctatata ttaaagactt tccagagata ccttacaaag
     1441 tctttaaaga cattcaagaa aaatatagtg atacgttttc actagataaa gactatgagt
     1501 tattgaatcc tataataaaa tttactatag ggggcgttac tttgaataga ataaaatttt
     1561 atattgattc cagtaaaaag accattaaac aaattagtac agaaactggt attaactata
     1621 caactcttac gaactattac cgtggtgagc gaaatcctag aaatactgaa acatggaata
     1681 tccttgctga ttatttccat gttcctgtaa gttatttgat gggattagac gaaacaaatt
     1741 ccatagaaca acctaatctt gatagaataa aaactgctcg tttagaaaaa aaggacaaaa
     1801 tagtcaagaa tattgccagt cttgactcag attattttac tgaattatct aatctatact
     1861 tttccatgac ttctttactt gaagtcaaac ttcaagaaga tgactccgac tttctttttt
     1921 taaaaagtat tctagaggac tcctttgaat acacgattct atttgccaaa caaaagaagt
     1981 ttattaataa agctttaaac ttaaatatcg atgaaagaaa agagttagaa tctgagttat
     2041 ttggcaactt aacccaagta caggttaaca atctaaaaag agagataaca gctcgattaa
     2101 tatcaaaact tcaataaaac taattattca atcagccaac tcgccaagtt atcagattgg
     2161 agagattagt tatgtcaata caaaagtaca caacaaaaag cggtgcacga tatagtgtcc
     2221 gcttgtatgt tcgtaaagat gaaaatggaa agcaagaata ctatgtaaaa aaagggttta
     2281 aaactgaaaa agaagccaag ttacacgaag caagaaaaaa ggtcgagatt gaagataccg
     2341 gctatcataa gccttctaat gacttgttta taacagtgta tgaagaatgg ttgccttctt
     2401 ataggaatcg tgtacaagaa acgacatatc aacgtacaaa agaccttttc cgcttgcata
     2461 tactaccaaa attcgggaat aagtccattt ctaagattac tcctgttcac tgtcagaatg
     2521 cagtcaatga atgggcttta aaattcaaga atatcaaaca gcttaagtct tacagctctc
     2581 aaatatttga gtatgccatt tttgcagagc tattacaccg aaatcctatg gcaaatacaa
     2641 atctaccaaa gcgggaaaag aaagaaaatg aaaattactt ttcattagaa gaactaaaag
     2701 ctttttggga tattctcaat aaagaagagc ctttaaaaca tattttaatc ttccagcttt
     2761 tgattactac tggtatacgt aaaggagagc tagctgctct tcattggtct gacatttatt
     2821 ttgaagaaca gctaatgtat gttagaaaga gctatgcaac tattcgaaat gaagagaaga
     2881 atgcaagaag aaaaactgtc aggattcaaa aaaatacaaa aaatatatct tccgaacgaa
     2941 tattaccaat tgatgcacaa actattgaaa tgttaaaaat ctggaaaaaa gaacaagctc
     3001 gagagctttt gcagtttggc ataaatacaa atacaaaaaa tcaacttatc tttacctatg
     3061 taaatgcaga cggtgacatt aatcaacctt tgcatgcgga ctattcaaat aatatattga
     3121 aacgtttaga gaagaaatat aaatttaagc acgttactat tcatggattc cggcacactc
     3181 acgctactct tctactagaa ggtggagcaa gtatcaaaga aacacaagat cgattgggtc
     3241 ataaaaatgc tgaaactacc cttaacactt attctcatgt tactgaaaaa gctcaacgaa
     3301 atgcgttaga aaaattcatt gcttacactg gtttataata ttgtcattac ctttctcatt
     3361 accagaacga aaaaaagaca ccttctcgca atgagaaagt gtctgaaatc gttggtataa
     3421 caacgattaa cgttttgaaa actgtgaagc tttacgtgct ttcttaagac ctggtttttt
     3481 acgttcgacc atacgtgcgt cacgagtaag taagccagca cgtttaagag ctaaacggaa
     3541 gtcaggatca acttctagca atgcacgagc gataccatga cggatagctc ctgattgtcc
     3601 agcgtatcct ccgccgttta cgttaacaaa tacgtcatat gcgccttttg tttcagtaac
     3661 agcgaaaggt tgattgatta cttcacgcaa gtcagcatgt ggaatgtatt cttcaacatc
     3721 ttttttattt acagtaattt tgccagttcc tggtactaga cgtacgcgag caactgcgtt
     3781 tttacgacgg cctgtgccga tatattgaac ttgtgccaat gaaattccct cctattagat
     3841 taagtttgtg atgtctaaaa cttctggttg ttgtgctgca tgtggatgtt ctgctccacc
     3901 gtatacgttc aattttgtaa attgtttgcg gcctaaagtg tttttaggaa gcataccttt
     3961 tacagaagtt tcgatcaaac gacgagaatt tttagcacgc aattcgccag cagtgattga
     4021 tttcaatcct cctgggtagt tgctgtgacg gtaataaatt ttgtcagtcg cttttttacc
     4081 tgttaatttc actttgtctg cattgatgac gatgacgaaa tcgccagtat ccaaatgagg
     4141 tgtgaaagtt ggtttatttt taccacgtag tacagatgca acaactgttg aaagacgtcc
     4201 caatggaaca tcagttgcgt ctactacata ccatttacgt tctacttcgc ctggtttggc
     4261 catatatgtt gtacgcacgt tattttcctc caatttaagt tctgatgttt gacatacact
     4321 tcgagtttcc ggggctcttt gtggggcaaa caataccatt taacatatta cccgctaatc
     4381 tagtcaatgt caacgttttt ctgcttgatt gaaaaattta tatgaaactt tacttctttt
     4441 ctttctttta tataaaaggg tcgtttcctg tcaaaatgaa aaacaaaaag aggctgtgac
     4501 aaaagtcttg tcacaacccc ttattttgaa taaacggtgt tctcctgcca actcctcggt
     4561 cacaagtcac aatatccata aaacataaga agctgttttt taaaattgtt tcttgtgact
     4621 cggagctgaa cggcaggctt acaacctctt ggtaaacggt gttcaatcag ctgaccctcg
     4681 gtattagctc aaaaaacggc aaaatatgag gaactatttt gacgtttgtt tctctaatac
     4741 tcaggtcaaa acgctgattt cacaacctct ttttcggtca agttcaacaa cagtttttac
     4801 gcgtcgatct ctggcgcttt gcccaaatga gcttggatca tccagatacg tttttctgtg
     4861 gctgttttga attcgataaa gatatcttgt gttggatcgt cgccttcttc tccagaaact
     4921 tcgattcctt tttggtaaag atctgctaga taacgatagc ctgcaacaag tgtttccaaa
     4981 cgttctggaa tagtacgatc ccagcggcca atttcatcag ggatttttgt gttatctgca
     5041 aattcacgca atgtagaata aggtgaaccg tctaatgtga tcaagcgttc ggatacttca
     5101 tctaactgag cgttcaaatc atccatgaac tcatccatca ttgggtgcaa tgtaaggaaa
     5161 cctggtcctc tcatgtacca atgtgtttgg tgaacaacaa cagacatttg gcttagatct
     5221 gcaactaatt gatttaatac ttctttggtt tgttggaatt tcatctttct tgcctcctaa
     5281 cattttctta cacttaaaat aatagtagac tttcaatgaa aagtacaaca aaatcattta
     5341 cctgagaacg attttcagtt cgctttttta tccgtaaagc caatcatttt tcagaatcag
     5401 ctaattcttc tcgcagttga gcaaattgct gataagtctg tgctaaatgc ttttgtgtcg
     5461 aaacaaataa tggatagatt ttctgatatt ttttatgatc agtttcttgt actccaactt
     5521 gctctttcaa ttctatcaat tcctgtgctt cactgatact ttggatcttt ccgatgcttc
     5581 tccagcctaa aatcacagct cctaatgcgg atgcttctgt gacagtaggg aaaacaagcg
     5641 ggtaacccag tacatcagcc atcatctgac gaaaaatcgg agattgagca aacccgcctg
     5701 tagcacggat ctctgtgagc tgattttcct ggcaaactcc ttttaaaatc cgataaaggt
     5761 tgagacagat cccttctaga atcgccttca tcatttcttt ttctgtatgt tgccgctgta
     5821 aaccgataaa actgccaaac gcatctgcgt cccaaagcgg tgctcgctca ccaagtaaat
     5881 agggatgaaa aatcagacca ttggcacccg ctggcacaaa agcgatagcc gaaagcagtg
     5941 catcatatgg attttctcct ttttctttag cagattgaac gacttcctgt aaaaatgtat
     6001 gccctgccca atcaaagatg ccagcaccat tgctagtcgc tcctcccact acccaatgtt
     6061 tctgatccag aacataacaa aacgtctcca tttctggatg gaactgaggc tgagtagtaa
     6121 taaaacgaag tgctccgctc gttcctacgg tcaaagcggc gatcgtatca ccaaaagcac
     6181 ctaaccctag attagaaagc ggcccgtctg cccctcccaa aacaaatgat atatcatttg
     6241 gcaaacctag ttctgctgct gtttttgatg gtagacctgt tacttgatag gtggaaggaa
     6301 agacttgcgg caattgctct attcgaatgt tcaagtagtc aagcacttct tctgcccatt
     6361 ggaattcatg gatatcaaaa tatccagttc ctgaagctgt tccgtagtcg ctgatcagtt
     6421 cgccaaacaa tctataaaag atatagtctt tgataccgac aaaataagca gtttttttga
     6481 ataattcagg ttggctgttt tgcagccact tgattttgtt caatggtgtc attggatgaa
     6541 tcggcgtccc agtctgccga taaaattctt tgccaagcac ggtatatttc agtttttctg
     6601 cttcgtccgc tgctcggtta tctgcccaag tgatcattcg agataacggt gttttctctt
     6661 catccaacaa tatcaggcca tgcatcgcag aggagaagga gacaaattga atgattgtgt
     6721 ctgaaggcaa ctgtttaatt acttctttta taacggtgca gacaccttga aagatcaatt
     6781 cctgatcttg ttctgccatc ccttgtgttt cttggatcaa agggtagcga aaataagcgg
     6841 atgctgcttc ttgggcttca tctgtgaaag caactgcttt ggtttgtgtg gttccgatat
     6901 ctaatccgat tgaaacgttc attttttcac ctcaaatttt atgtatgtac aaaaatttag
     6961 tttaagcttg cgtatcttgg ttttgaaaag ggggagatgg cgtgttactt tattttatca
     7021 ttggttgctg tatcggatca tttttatgtt taaccgccca gcggattccg ttaggtcact
     7081 ctattattta tcctagatct cattgtgtca aatgctgtcg ttcgctttct tggtatgaat
     7141 tgattccgat tctctcgatc atcgtccaac gatttcgctg ccgctattgc aggtgtcggt
     7201 tgcccttcta ctatttgttg gcagaagcct tatgtggtgg tctttttgcc tggttcttta
     7261 ctttttcttc cgcaagaaat ttttcgacgt tcatatggat gctttcggct ttgctatttt
     7321 cgttgatgga tttattttac ttcatggtcc attctcacac gctattctgt tcttgggcaa
     7381 ttttatggat tttttggttg caggccggcg tcttccaatg gcaaagtgtg ctgttaacgt
     7441 ttatcgtagg cggtgtgtgc cttcgctatg gtcaatccta tctcggagct ggcgatactc
     7501 tgttgatgct ttcttggagt ggtggcttgt ctctagaaga gttgcttcag atcttgtttc
     7561 ttgctagtct gtttggaata tccgtttttt ctgtttactt tatctgtcat aaaaaaaagt
     7621 tggaaaagct gcctttcatt ccttttttga gcagtgcgtt gctgattgtc cttcatctta
     7681 ggtattgaaa aaaggttgtg acaaacgact tgtcacaacc tctgatatat agtgttctct
     7741 taccaaatcc ttgtgacttg gagctaggcg acaggttcac aacctctcca ctaaatggtg
     7801 ttcaatcagc tgaccctcag tattagctca aaatgctggt tttacaacct ctgatatacg
     7861 gtgttccata agtagctttt tcggcttctt atttcttgac gccccaatgt cgacgaagga
     7921 aacctgcacg tccagaacct tctcgataaa gattgtaatg gagcttgttt ttcttgtaat
     7981 aatcctgatg gtaatcttct gcaggataaa attcgcttct tggttcgatt tttgtcacga
     8041 ttggcttatc gaatcgcccg ctgtcttgca atgcttgttt tgaacgctct gcaatatttc
     8101 gttcttcttc atcattatag tagatcactg gacgataaga atcaccgcga tcagcgaact
     8161 gtcctaatgc gtcagtcgga tcggtttgct gccaatagat ttccaccaac tgatcataag
     8221 aaataacttc tggatcatat tcgatctcta ctgcttctgt atgccctgtt gtgcctgttg
     8281 ttacttgttc ataagttgga tttggtacat gcccgccagt ataaccggat gtcacagaaa
     8341 tgatccctgg ctgctcttca aatggtttga ccatacacca aaagcatccg cctgcgaaaa
     8401 ctgctttttt tgtcatataa aatccccctt ttttctcatc ataccttgat ttccaaaagg
     8461 aggataacgt tttgcttgtg acagaaaaaa cggaaactat tatatacgtg atacggcttc
     8521 tgataaatgc caaaacgaac gtacttgatc aaaaacggtt aaatcaggaa tcacatattc
     8581 agcagaagga agatttatgt tttcacctat tcccaataca tgcatgttac cagccaaagc
     8641 tgcttgacaa ccagcttctg aatcttcaat gaccaagcat gcatttggcg gtacattcaa
     8701 ttgctgtgct cctttgagaa aaacttctgg atcaggtttt gcttttgata cttgcgtgcc
     8761 gtcaataagg acatcaaaat aacttgtcaa attcgttttt tctaaaatga ggcgtgcatt
     8821 tttgcttgct gatcccaatc cgatcttgat gtttgttttt ttcaagtact caagaacagc
     8881 tattgcacca ggcaaaacgg atgtttcatc cattttttga atcgcttgaa gatatagatt
     8941 gtttttttgc tcagcaaagg ctgatttctc tttttctgag aatttctgtt ccatttttcc
     9001 aaatgacagc aatcgctcta gtgactcggt tctggatatt cctttcagtt gctcgttttc
     9061 tttctcagtg aatggaatgg acagctggtt agctaaaacc agccacgctt cgtaatgata
     9121 acgagctgtg tctacaagaa cgccatctaa atcgaatagt gctgctttga ttttcatcga
     9181 ttacctcctt gaaaatgaac gacttgaagt aaagatgcga tgtttttagc tgtgcgatga
     9241 agattatcag tggcttgctg taaagcttct tgtaaaggca cagctgcagg aaggatcgga
     9301 aaaacggccg aaatgccaac atctgctgct ttttcgcttc ctttaccaac acttccgcaa
     9361 atagctatca caggaacgcc ctctggtact cttctagcaa tcccaactgg cgcttttcct
     9421 tttagacttt gtccatctag acgtccttcg cctacgatta cgaggtctgc ttgctgtacc
     9481 cgtttatcga actccagtaa atccaatacg tagtcgatgc cagagactat tttccctgaa
     9541 gcaaatgcta acagtcctgc acccattcca ccaccagcac tactgcccga tgcctcgatt
     9601 acttgagggg caaatctcat ataaaaatca tgcatggctt ggtcagccac tgctaattca
     9661 ttttctttca agcctttttg tggtccgaaa acaaaagaag cgccttcttt tccgcataaa
     9721 agattagtaa catcagtaat gacagtgatt ttggctttaa tcagctcaat aggcacgttc
     9781 gttttatcaa ctgtagcaat tttacctaga ttttctccca gtgcttctac tttttgatta
     9841 tcttgatcgt aaaaagcata acctagacct tctgccatgc cgatgccgcc atcgttggta
     9901 ctacttccgc caacgccgat gatgatgtgt cgaacacctt gttgcaacaa ttgtcgtatc
     9961 agttctccta ctcctcgcgt ggataaccta agtggctgtt gttggtttag tgggacatct
    10021 ttcaatccga cgatttctgc catttcaaaa atcgcagttt gaccgtctga agcgtactgg
    10081 atttctttgt ttttgccaaa tgcattagta acgactgctg tttgccgctt caaccttaaa
    10141 ctgtctgcta atgatgaaac cgttccttct cctccatcgc ctataggtag cagatcatat
    10201 tcagcctgaa caaaaacttc ttgaaaacct gattgaatgg cttgtgctgc ctctaaggct
    10261 gtcagacttt ctttgaaaga atctggcgca atcagaatac gcattatttt cccctccgtt
    10321 ccaagatcag ttctttttcc agctggtatt ggtctccatt gacaaaaata ggtaatgttt
    10381 ctttcgtctc tttttttatt actatttgtt tttttgtcaa aacaaatagc aacctgtgat
    10441 ttttccaaat aaaaggaaaa gaaatttttt cccatgctga aggaagtctt ggagaaatag
    10501 aaagagttcc attcgttact gtaatacctg aaaaaccaaa tataactgct agccatagtg
    10561 ctcctaatga agcagcatga attccgtcat ctgatgaatg cggatctggt cctaaatcaa
    10621 tcaggcacgc ttcttggaat aaatgatacg cccattccat ttcttggata cggcaagcct
    10681 ctatggcgtg aatcgcttta ctcaacgatg agtcgtggat tgttttgttt tcatagtaat
    10741 gcaaattctt agaaacgatt ggttgagaaa aatactcagg taataagtat aacagcatga
    10801 caagatctgc ttgcttgctg acttggagtt catttacttc gctacgggca taatcaagta
    10861 aaatagactg gctgccagga cgttctttgt aagtggtcaa atcaataact ggcttactga
    10921 gatacgtgtc atcttgcgga atcagctgtt ctttgttagg cactggcaaa tataacttat
    10981 ctaaaaaatt ttgacattct ttcaaaaaaa gcggatcgcc agcttgatat ttaacagcta
    11041 aggccacatt ataatgcgcc agatagttcg tatatgcatt attgtcgata tattctgtgt
    11101 attcatctgg accaatgact ctgtgtatct ctaaatgatc atcgactttt acagctctgc
    11161 tcagccaaaa agctgctgtt tcatgaatga gcgtttttcc ctttgtttct aaaaacgatt
    11221 gatcctctgt tgcttggaca tactcttgaa cggcataagc aaggtctgca ctgatatgat
    11281 gttctgcggc agctgaagca acttcttgtc ttgttccggt tttgatattc aatgcagcaa
    11341 atttgggtgt ctcttcctga ccagtgtgtg cgctttccca tgggaaaagt gcaccttgat
    11401 agtgataatc tcttgctttt tgccgtgcgc cttctaatcg atcataacgg tacagcagca
    11461 aattctttgc tacttcagga aactgatata aaaagaaagg caggataaaa atttccgtat
    11521 cccagaaaac atgcccttta taaccttcgc cagttagtcc cttcgcccct acactaacac
    11581 ttggatcatt gcggggagtc ataatctgta aatggtaagc agcgaagtcc atcgctaact
    11641 gatcgaaaga agaatcgcct tggatcgtta tccgatgctg atgccaaaaa tctgtccaat
    11701 aagacatcga ctgctctaaa atttctgtat aactaacgct tttctgggct tgggcaatac
    11761 ttttcttaaa cgggtctgtt tgctgaagag aggtagagag cacgatgatc ttctccagcg
    11821 taaaggacgt attttttctg atcttttctg aaaaggaagc ggtgatccgg cgattttttg
    11881 cttggaatac acctgcttta ttgaatttag ctgcaatccc aatatcaatt ttactttctg
    11941 ttgtctggta ggatgcactg atcaaatcgt caccaaatac tcgcagttct ttttcaacca
    12001 actgctgtgt accaaaattg gtttgctgtc catcgatacc cgttttcaca tctacttggc
    12061 agtcttcggt caacggcttg atgaccactt tcagggctgc ctgatggaga ttattttgat
    12121 cagcaacacg acaagtaatg acttccactt tttttccttg agcagtttca atgagcgcat
    12181 agcgtttaag ctctcccatt tctaaatcta gtgcccgctc gtatgcaaga actttcatcg
    12241 tctcaagaga aaaatgttca ccgtcgattt ttatttccca tctgatgaca tctgggagat
    12301 tcactaactc ggctgattct gctcctaaag gtcggttata tacaccagct gcaaacattc
    12361 cccttacttg attccgatag tcttcctcct ggcttcctct gataccaaaa aatccatttc
    12421 caatggtcat ctgactcgca tacttattga tatactctaa atcaaactgt ttttcttcta
    12481 ctttcataag gtaataactt ctcctgtttc tgccgaacga tataaatttt ccaccagatt
    12541 ctggatgaca tatccttgcc agccatctgc aatcatctga gtctggtcac cgagcgcccg
    12601 attcacaaaa tgagccatac ttagttcatg tgggtcatta actggcgtgg tcttttgtaa
    12661 ggaaaccagc tttccatcta catcttcgaa tagttcgcct ggatacagat tagcacctgc
    12721 ctgatcgcca caaaaagcca cattcagttt gtcttctctg atattcaaag caaacgaagt
    12781 attcagttgg atgatcttgc cgttttctaa ttccagtgtg ccaaaaattg catcttctac
    12841 tgtgaatttg cttggatccc atttcccgaa tttccctgaa ttttttttcg taccaatttt
    12901 ttggaagctg tacgcccgaa cgctttttac tttaggaaat ccagtaatat acatcgctgt
    12961 atcaagcatg tgaatgccat aatcgatcaa aggcccgcct ccttgaagtt ctttgtcgat
    13021 aaacgttccc cagcctggaa caccagaccg acgaagcgca ttcgcttcta cgtaataaat
    13081 atccccgaga acatcaagat gattcttgat cattgttgct tcgtcagaaa aacgatgctg
    13141 gaatccataa gccaaaatct gcccgttttt atcggctgtc tctgccatct ttcttgcttg
    13201 atcagctgtc atagctggtg gtttctcgca catcactgaa gcattagctt cgagggcagc
    13261 caatacatgt tcgaagtgaa agcgattggg tgtacagaca ctcacgatat cgggagaaat
    13321 ctcattcagc atttgtgtaa ctgatgtata cgcatgagaa aatcctgtac gtcggcaaaa
    13381 gtcttctgct cgctggctga ctggatcaac cacagcggcc aattctaaga catctgatct
    13441 tttttgataa taagcagcat gtactttttc tgctacttgt ccagcgccta tgattgctac
    13501 tttcttcatt tatttctctc tcctttgctt atttacttat tgttattctt tctctattct
    13561 ttctctaaat catttaaatg acgcgctgtt tccagacagt ttttcaagta ttgcaatgat
    13621 tcctgataaa ttttcacttc attttctcct cgcaaacgac attcatatac catataacct
    13681 tcatactcat tttgaagtag cgtttgaaaa tggcgagtaa aatcaattgc gccagatcct
    13741 ggttggtagc gatgattatc tgctaaatgg atatgaccca catactcttt ttgcgtagtc
    13801 aatgcttttg aaatatcatc ttcttcaata ttcatatgat aaaaatcagc gatgatctgc
    13861 acatgtttca attgattaga gtcaatgtaa tgacgcgcat ccgctaacaa attgatcata
    13921 tggtcttggt atcggttcaa aggctccaaa taaataaccg tacctgtttc ttcggctact
    13981 ttatctaaat aacgaagtga ttcgctgact gctttatagt ctccttcttt gcttcggggt
    14041 gaaaccatcg gcggtaatcg ataagtgaac attccccaag ctgctgggat aacgattcct
    14101 ttgcctccaa cctcgcttag tgcacgcaaa atctcagcaa tttgacgtac accattaaga
    14161 cgccgttctt cgataaagtc accgatccac ccatcgtagc cgttacaagc tgtcactact
    14221 gggatccctg tttctttgat tgcctgtttg actgtgtcga tattttctat taacaactta
    14281 ccgtcgattt cgtattcttc aaatccacag tctttgataa atctaaattt ttctaaaatg
    14341 tctcttggga aaaatgcttg atcttgcgta ccgaatttca ttgttctcct cctcggactt
    14401 gaacgcccat tttgatactt tcttctgggt gctggtctac ataacgcatg taagcttctg
    14461 cgctttctgc aaatggcaca actggatcaa tgatttcttc acaatccaag taaccgttca
    14521 tcaataattc ccaacatgtg tcctcgattc gtttacggtt ccatcttggg taatctgggt
    14581 ttggttcact agatgctcga gcaaagacga tttttgcatt attgaaatgt gcttcgcgac
    14641 caagattaaa cccagctgga aaaggtttag caaaggcaac ataagaaatg atcccgccat
    14701 agccgatccc tattaaagaa gcttgtaatg cggcagcact gccactcgtt tcaataactg
    14761 aatctactcc acgtttatct gtcaattcct ttagacgaaa accgacatct gctttcatag
    14821 gatctagcgt gtaatcggca ccgtgttttt ctgctaattc tctacgctgc gctatgggat
    14881 cgatcccaac gatggtagta gcacctgctt ttttagctaa ttgaatcgca atttgcccga
    14941 tagcgcctaa accgaagatt gctacagcat cacctgctcg aacatgtgct tcccggatac
    15001 cacctaaagc gaattgagca ggatcgtaac atactgcatt tttccattga tccaaccgat
    15061 caagtttacg tagtttataa ttatcaacac cgtttgtaat cagcgtttca cgaatgggtc
    15121 cataagtgca gactaactct cctttttgat actctgtcac caaactgccc gtttcttcga
    15181 tcgtaccgac aatcatattt cctaattgaa attcgccaaa taccacaccg cgttggcttc
    15241 cttcttctct tggcaagaat aggcgccatt cttctgaaaa ttcttcatcg ataaatggac
    15301 ttaatcctct aaagtcgaca atttctgttc ctggttttgg agtagcgaaa attactcgga
    15361 tacgtacttc gttcttttcg atctcacggt cttcgtaatc tttgaatccg gctattcttg
    15421 gttctaatgc aactaatttt ttcatctttt ctttcctctt tcttttcttt ttatcctttt
    15481 acgccgcctt cgactaaatc acctttaata aatcgttcag ataacgcata cataatgatg
    15541 actggtaaag cggtcaccaa tgaagcggcc atcattcgtc cccaaatgta gtctggtgta
    15601 ctgaataatg tgttcaaacc gattggtaaa gtaaattttt cggaggtcga caggaaaatc
    15661 gaagcaaata aataatcatt ccacgaaacc ataaagcaat aaacgaagac agaaatgatt
    15721 ccagaaatag ccaatggtat aatgatccga ataatgatct ggatccggct aagaccatcg
    15781 atcattgctg cttcttcaat atcagtcgga atcgtgtcaa aataactttt tagcatgaat
    15841 atcgcagtag gaagtgtttg aacgaccatc gtgataatca gtgctgtatt ggtatcatac
    15901 aaacctagac cggaaatgat tttaaataat ggaacaacga tcaaaatacc ggaaaacata
    15961 taaacggtgt aaaagctagc attgattttc gagcgagctt tgaagcgtag ttttgacaaa
    16021 gcgtatgccc cgctgatccc aatcactact gcagttacgg aggctatcaa ggagatcact
    16081 aaactatttt tgaaatacat gatgaatgga aaaatctcag cattgaaaat atcctgataa
    16141 tgttcaaaag tccattcttt cggaaaaata gtttgtgtcg ttgcaattgc ttcttgtgaa
    16201 tccttgaatg atgtcatcag catgatcaaa aatggaaaca aattgacagc taatagcaac
    16261 aaaatcgtcg cgtaaaataa gattttcctg ctctttttat ttttcatttc aagtccacct
    16321 tctttcgtga gagcaagacg accgctgcaa taatgatgaa caatagaatc gatatagctg
    16381 ctgcttttcc aagatcattg aacgcaaagg ctgtctgata caaataaacg cctaagatat
    16441 tgactttatt cgtcagtaga tagacatctg taaacatata gaacatccag atagatcgta
    16501 aaacaatcac agttgctagt actggtttga ttgccggcag tgtcacgatc ttgaacttct
    16561 gccaagcatt tgcaccgtcc atttcagctg cttcataaag cgttttgtcg actgtttgca
    16621 aaatagccaa aaatgaaata aacgcatacg gatagtatct ccagatagca aacaaaacga
    16681 ccataaagaa gctagcaact ggctggtcga accacagcgg tgcttcgttg aaaagctgca
    16741 acctatctac taacagatca ttgacgattc cataactatt attgaacata tatttccaag
    16801 caaaaatcaa agaaatagat ggcgtaacat aacttaataa aatcagtgaa cgcaccgttt
    16861 tcctaaatct gaacttgcgg ttaagcaaaa tagctacggc taatcctaaa gctgtactgc
    16921 ctgctacaac taagaatgtg taagcaactg ttaaacctaa agaacgataa aattcactat
    16981 cacttaaaat ttcaagataa ttgcttaatc cgataaaaac ggcgtctgag ttaggattca
    17041 gcggcatatc gaaaaaactg atctgaatat tggaaagcat tggaatcagc actaaaacag
    17101 ctaataaaag catgcttggt gctaaaagtc ccatggctaa ttttaagtca gaatgtttcc
    17161 ttggacgatt cattgaaacc tccccctgat aatctgccaa tagctatcta cttttttcga
    17221 acaccattgg cagaacttct tgttatttcg tatttttttg tgcgtcagct aaagcttgat
    17281 cgacatcttc gtttccgaca gttacttggt tcactgcttt tccgatcaca cctgagcttg
    17341 tgatatctcc cattttcgtg aaattctttt ccccgactag tccaaagact tgtacttcat
    17401 caaaagcact agcaatctca gatggcagct cgccaaaaga cttgatgact tcattttctt
    17461 tgtaaccatc cagttcgact acttgtttat tcactggttg agcaccacca ggagacatca
    17521 agacccactt ttccatgttt ttcggttgag ataagaaagc tgtgaatgct tcagcagcct
    17581 ctttttgttt ctcgtctaga ccagaagaaa tcgtcaatcc agatactgtg ccatagacag
    17641 cttgatcttt ttgtgttggg atagcaaaac cgatattttc tgagttcccc gcttcataaa
    17701 cagaaggcaa aatgtaagtt gaatagattg ccattggtgc tgttccattc atgaaagcat
    17761 ctttgatttc tgtcacatca ttagagcctg gcatcgtgta ttgggataag ttttgataaa
    17821 acgacaatgc ttctctcatc ttttccgtat cgatcgttac ctcgccttca tcatccaaaa
    17881 catttgctcc atttgacaaa gcaaattgag agaacgcttg ctcactcatt gttccttcag
    17941 cagtaggcat agcaattcca tattgtttat tctctttatc tgtgaaatgt tgagcaattt
    18001 ttaaaatatc atcccaattt tctggttctg aaaaaccagc ttctgataat ttttctttgt
    18061 cataccaaat accttgaacc cagccgctaa ttggtgcagc aatatagctt tttccatctt
    18121 ctgaacgaac aaggtttttg gctccgtcat aataattatc ttctccagct tcctcgataa
    18181 cgttttggac tgccgtctga tcaatcagtt catctttatc catcacttta gcaaaatcct
    18241 gactgacttc cattacttct ggtaatttac cggaacgagc taacgtaacg atttttgtat
    18301 tgaacgctga ttcttctacc ggcacttgct tgattttgat gtctggattt tctttttcaa
    18361 aatcagcaac cagttcattg atcacactta atcgttcctg ttcgacagaa gagtgcatga
    18421 attgaatcgt tgtctgttgt gattcgttag agctttgact ttcaccacaa gcagtaagaa
    18481 gaaatccagt agctagcaga caggtagtaa caataatttt tttcattttt ttccacctct
    18541 tattttatta ttttcagcca catatattca tacggctgga atatcaactt tcgttcttga
    18601 ctgcaatgga taatttgtcc agaaaacagg tctaggtaat ctccttttgg taaaagataa
    18661 cctgctgatt gattggaaaa attatggata actaagactt tctcttcctt cgcttcgcga
    18721 ataaaactga taaaagaatc tgctgagtcc agtaagtaaa tcaaactatt cggatggaag
    18781 gctttttctt tttttcgaat agatagcatc tgggtcaatt caccatatac tgctgttctt
    18841 aatggatctg tctgcaactc tttctcaata tctgctaaca aaaatttttg ccgattgatt
    18901 tttcgattct ctcctgtttt ttctacgcct ttgtaatcat ttcgacttcc cagcacactt
    18961 tgaatataaa ttgccggcac gcctggtaac gttaccaaaa atgaatgagc agctaaaaag
    19021 cgtttgcttc tccattccgt cgtatctgtt ggagaactta acgcatctag atacgtagcg
    19081 tttatctcat atggactggt cgttccatct gggtttttct tgtagtttac tcgggcaccc
    19141 tctttcttca gctgttccac taattcaagg atcgtttttt ccggcagaat acctcgtacc
    19201 ggattcaatc cgataccgtc atgggaggct aaaaaattaa aaaaagttgt ttttttcgat
    19261 gcgaaatcga tggtttttaa ccattctttc aacttacttg tattacccga acgaatcgct
    19321 tgaagggtca aaggtggtag cgaaaactga tagaccatct gtgcttcatt ctcgccattc
    19381 ccaaaataac tgatattatc tttgtgtggc acatttgtct cagtgatcaa taccgttcct
    19441 ggagctgctt catcagcgat tgcacggaat aattggatga ttttatgcgt ttctggcagg
    19501 tgtatacaag aagttcctag ttctttccat aaaaatccca cagcgtccaa gcgaataaat
    19561 gaagcgcctt tttctaagta aaacaaaaga atatcgatca ttttcaataa aacttctgga
    19621 tttttaaaat tcaagtctac ttgatcttcg ctaaaagtcg tccatacgtg tttttctttc
    19681 ccgtttttgt caatgaacgt tgtaagtaac gggctggtcc ttggtctagt cacgctgctt
    19741 gtatctgtat ccagtggcaa atcaataaaa aaatctttgt acgtatcatt caagtttaaa
    19801 tattcctgaa accaagtact ttcggcagac atatgattgc agacaaagtc gaacattaac
    19861 cgtgtttcgc ttctcatttc ttctatatct tcccatgtgc ccaaacggtc gttgattgcc
    19921 tgataattta caacggagaa accatcatca gatgtatatg ggaaaaatgg caagaaatgt
    19981 acaactctaa atgtatctgc caaatacttt tgataaaatt tcttaaatgt acgcaaagtt
    20041 ggttgctgct cttcaaaaaa ttgatcccca taagtaatca agaaaatatc ttcttcgtcc
    20101 caatgcagtt tgcctgcctg gcctttcttc tgctgataaa cactgacttt ttgttcaatc
    20161 atagaggcgg ttttctcaga caaatctgag tcgcgataaa tcgcttgtaa aagttttgta
    20221 tacatcggat tcccctttct tttttgggag cgttcccaac gatttgatca tattatggaa
    20281 aacgcttact gtcaatagca tttttttaaa taattttgat atacacaaaa atacaaataa
    20341 gaaagcttat gtatcaataa ttaatagctt cttaaaaaaa tatggtctct catgatcatg
    20401 caagctattc ctaaattttc aaaatcatag acaaaaaaga atgtctattg tactatggaa
    20461 ttattctaaa acgctcccaa aaaggaggtg catataaaat tgaaacctac tatttatgac
    20521 attgcgaaaa aagctaatgt ctcaaaatca actgtctcca gagtattaaa taaccagcca
    20581 aatatctctg ataaagcaaa agcaagtgta cttcaagcaa tcaaagaatt gaattatgaa
    20641 ccgagcaaaa ttgcaagagg actgtcagga aatggttttg acgcgattct agcattatct
    20701 catcgtactt ctcatacgac ctatggcaat cctttttttt cagatgttat tcaatccatt
    20761 tctgccgttt ctgaacaaaa taacttcgac ttgattctac aaacggcaaa aacaccagaa
    20821 gaagagctag aaaaatgcgc gaaaaagatc caagaaaaaa tgatccgagg aattattatt
    20881 ttaagctcta cgatggatga aacacttctt tttgaattgg atcaatacaa tattcctatt
    20941 gtggtaatcg gaaaagtcgg aaacgactac acgaacatct actcagtgga cacggataat
    21001 ttccaggata gttacgattt ggtggaaaca ctgatcaaga atggacaccg tcatatcggc
    21061 tgtctccatg ctccgacaga agtttatgta tccaatgatc gtctcaatgg ttaccgtcaa
    21121 tgcttatttg atcaccacct agatatccgt aatgaatgga ttatagacgg cggctttcgc
    21181 ttagaagata gcatggcagc aatgaatgat ttaatgaagc tacgagaaag accaactgcg
    21241 attttttcta ccgatgcatt aaaatcattg agtatttaca aagtggcaga acaatctgga
    21301 aagcagatac ctgatgatct ttcgatcgca ggattcagtg atcccttatt gtcctcccta
    21361 ttttcgccac agttgactcg gatagacatt ccgacaaatc agttaggaat caaagccaca
    21421 gaacttttat tccaactaat ccaccaccaa taccctgaag aaaaaagaat cattctttca
    21481 accgagatta ctctcacaga ttcgatccaa caacaagaaa tgtagaacag aattataaaa
    21541 gaacagaaac actgaggata agtcagttac tctgttcttt tttcaatcac tcatccctcg
    21601 ttaccccctc ccggtatttt agcgaatttt tcttattttc catctgtttt agatagctgt
    21661 ggataactat aatgtttgtg ttaaactatt ttttccacag ggaagaaaaa actattttta
    21721 accacgttgt gtataagttt ttatagttcg tttttttaaa cacatttacc cttatttcaa
    21781 tccatgttat ttggggatac ttatctctaa aacataaata gaataacaga catgtctact
    21841 ggttttgttt tattcgagga attattcaat aatagctagc aaaatattaa aaataaccgc
    21901 tctatcttcc catcaattta ttttgcattc aaaaaatgat ctatctttac ttttgttgat
    21961 tgacttctct tggaagatga tcgttccgat accttaattg gatacgaacc gatgttgtta
    22021 agatcctttc ccacttttct tctagttaga caaattattt tagacaaacc aaaaaagagg
    22081 ttgtgacaat aatttgtcac aacctctttt ttaaaatatc tattttgttt gattgttcat
    22141 tgcgtcttct gcagccattt gcgcttcaat atctgaaata ctgtagacat tttcgcttgc
    22201 tacaccgact tcttttggtt ccatgtcacg ataacgttgc ataccagtac cagctgggat
    22261 gatcttacct ataataacat tttctttcaa accaagaaga ggatctttct taccgcggat
    22321 cgcagcatcc gtcaagacac gagttgtttc ttggaatgat gcagcagata agaaactatt
    22381 tgtttctaat gatgcttttg tgatacctag taagacaggt cgagaagttg caggaacgcc
    22441 tcctgagact agcgtattgt agttttgatc tttaaagtct gcgatgtcta ataatgtacc
    22501 tggtaagata tctgtatcac ctggatccat tacacgaact ttacgcagca tttgacgaac
    22561 cattacttcg atatgcttgt cgccgatttc taccccttgc atacggtaaa cacgttgtac
    22621 ttcacgaagc aagtagtttt caacagataa tacatcgcga acttgcaaca attgttttgg
    22681 atcgattgat ccttctgtca atggtgcacc acggtggatc atatcgcctt ctgctacttt
    22741 catacgtgct gtataaggaa cagtatacgt acgtgtatct gtttttcctt tgattgttac
    22801 ttctttggta cgtgttgcag gatcttctga gatatcgatg acatcccctg ttacttctgt
    22861 gatcactgct tgccctttcg gattacgtgc ttcaaagatt tcttggacac gaggaagacc
    22921 ttgagtgata tcgtctccgg caaccccacc tgtatggaat gtacgcatcg tcaactgagt
    22981 accaggttca ccgattgatt gagcggcgat cgtaccaact gcttctccga cttcaacgtc
    23041 agagccagtt gcaaggttgc gtccgtaaca atgtttgcag acaccatgtt ttgtattaca
    23101 tgtgaagaca gaacggattg tcactgtttc gacacctgca tcaacgattt gttttgcgat
    23161 gtcttcggaa atcaattggt ttcctgcaat gatcaattca tttgtttcag gatgacgtac
    23221 ttctttacgg gtgtaacgtc ccactaaacg atcttctaat gattcgatga tttcatttcc
    23281 ctcgcggatg gcttggattt caagacctcg gtcagtaccg caatcttctt cacggatgat
    23341 tacatcttgg gccacgtcaa ccagacgacg agtcaagtaa cctgaatcgg cagtcttcaa
    23401 ggctgtatcg gtcatccctt tacgagcccc gtgagttgag ataaacattt ccaagacgga
    23461 tagtccttca cggaagttcg aaatgattgg caattccatg attcgaccat taggagcggc
    23521 catcaaacca cgcattccgg caagctgtgt aaagttggaa atgttaccac gagctccaga
    23581 atcagacatc atgaagattg gatttttcgc ttccaaacct tccatcagtt tttgttggat
    23641 gctgtctttt gcagcattcc aaacagcaat gacacgttca taacgttcgt catctgtgat
    23701 cagaccacga cggaattgtt ttgtaatagt ttcaacttgt ttatgggcat tttcaatgat
    23761 ttcttgtttt tcattcagta cactgatgtc agcgatccct actgtgatac cggcatgtgt
    23821 cgaatgtttg taccctaagt ctttcatacg gtcaagcatc ttagaagttt ctgttacttt
    23881 gaatcgtttg aagacttctg cgatgatgtt tcctaagttt ttcttcttga acggtaatac
    23941 taattcttgc tctttgatat gtgcaggaat atcagtacca gcttcaacaa agtatttgtc
    24001 cggtgtttgg acggtcaagt tgaagtctgt tggttcattc agataaggga attcaggagg
    24061 catgatctcg ttgaagatga tcttaccaac tgttgtgatc atcgtacgtt ctttttgcca
    24121 ttcagtaaat ggtttttcac ctaatgagtt agggttcaca ccgatacgtg aatgtaaatg
    24181 aacatatccg ttgcgccatg cgataacggc ttcgttttga tctctgaaga ccattccttc
    24241 gccttcgcgt ccttcttctt ccattgtcaa gtagtagtta cctagaacca tatcttgaga
    24301 aggagtaaca actggtttac catctttagg gttcaagatg ttttgagcag ctaacatcaa
    24361 catacgtgct tctgcttgtg cttcttcatt caatggaacg tggacagcca tttggtctcc
    24421 atcgaaatcg gcattataag cttcacatac aagtggatgc aaacggattg cgcgtccttg
    24481 tactaaaact ggttcgaatg cttggatacc aagtcggtga agcgtaggtg cccggttcag
    24541 caatactggg tgttccttga ttacgtcttc taaaacatcc catacttcgt cttcttgacg
    24601 ttcgatttta cgtttcgcat ttttgatgtt tgaagctagt tcgcgttgaa caagctcacg
    24661 catcacgaat ggtttgaata attcaatggc catttctttt ggaagtccac attggtacat
    24721 cttcaagaaa ggtccaacaa cgataacgga acgacctgag tagtcgacac gtttacctag
    24781 caagttttga cggaaacgac cttgtttccc tttcaacata tgagaaagag atttcaatgg
    24841 gcggttacct ggtccagtaa ctggacgtcc gcgacgaccg ttatcgatca atgcatctac
    24901 tgcttcttgc agcatacgtt tttcattttg aacgatgatt ccaggtgcat tcaagtctaa
    24961 caaacgtttc aaacggttat tacggttgat tacacgacgg taaagatcat tcaagtcact
    25021 tgttgcaaaa cgtccacctt ctaattgaac cattgggcgt aaatctggtg gaataacagg
    25081 gataacgtcc ataaccatcc agcttggttg atttcctgaa gcgcggaatg cttctaaaat
    25141 atccaaacgg cggattgcac gtgtacgttt ttgtccttgt gcagatttca attcttcttt
    25201 caattcggct gcttctgcat ctagatcaac attatcaagt aattgtttaa tcgcttctgc
    25261 acccatagca gcttggaatt cttgtccata ttgttcacgt ttttcgcgat attcgcgttc
    25321 tgtcaacaat tgttttttct ctaaattcgt atttcctggt tcgatgacta catatgaagc
    25381 aaaataaatg atttcttcca aagcgcgtgg gctcatgtct aatacaagac ccatacgtga
    25441 aggaatccct ttaaagtacc agatatgtga aacaggagct gctaattcaa tatgtcccat
    25501 gcgttcacgg cgaactttcg aacgagtaac ttccactccg catcgatcac aaacgattcc
    25561 tttataacgg atacgtttgt attttccgca ggcacattcc cagtcttttg taggaccaaa
    25621 aatccgctca cagaacaacc cttcgcgttc aggttttaag gtacgatagt taatcgtctc
    25681 aggttttttt acttcaccgt aagaccagct tctgattttt tcgggagaag ccaaacctat
    25741 ttgcatactt tcgaatttat ttacatcgat caaaaggggt tccctccatt tcatttaatg
    25801 gcaaaccgca agacggctga tcttcgaccg ccttgcagct catagaccgg attagtctaa
    25861 attatcttct gcggtttcaa agttttggat gacatcgtct ttttcatctt ccacttgttc
    25921 agcagctttc ttttctaatt ctttggcagt ttgctgttcg gcaaattttg tcaaagcatc
    25981 aacagtgatc aaatcgtcgt cttcatcgtc catgtcgcga agttcgatct ctgtttcttc
    26041 gatatccaag acacgcatgt ccagacctag tgattgcaat tctttcacca atacgcggaa
    26101 tgattccggt acacctggtt ttggaattgg ttcacccttg acgattgctt cgtatgtttt
    26161 cacacgtccg actacgtcat ctgatttgta tgtcaagatt tcttgtaaag tataagccgc
    26221 accgtaagct tccagtgccc atacttccat ttcaccaaaa cgttgtccac caaattgagc
    26281 tttacctccc aatggttgtt gtgtaaccaa tgagtaaggt ccgattgaac gtgcatgcaa
    26341 tttgtcatcg accatgtgag caagtttgat catgtacatc acaccgacag acacacgtcc
    26401 atcaaatggt tcacctgtac gtccgtcgta cagaacagtt ttcgcatcgc tggccatacc
    26461 ggcttcacga actgtttccc atacgtcttc atcacttgca ccatcaaata ctggcgttgc
    26521 tacgtggata cctaactgac gtgcagccat acccaagtgt aattccaata cttgcccgat
    26581 gttcatacgt gaaggcaccc ctaaaggatt cagcatgata tcgattggtg ttccatcagg
    26641 taggaatggc atatcttctt ccggcataat acgggataca acccctttat ttccgtgacg
    26701 accggccatt ttatcccctt catggatttt acgtttttga acgatataaa cacgaactaa
    26761 catgtttacg cctggtgaca attcatctcc agcttcacga gtaaagattt tcacatcgtg
    26821 aacgataccg ccgccgccat gtggtacacg taatgatgta tcgcggactt cacgagcttt
    26881 ttcgccaaag atcgcatgca atagacgttc ttctgcagat aattctgtta ccccttttgg
    26941 cgtgactttc cctacaagca aatcgccatc ttggacttct gcaccaatac ggatgatacc
    27001 catttcgtct aaatctttta atgcgtcttc cccgacatta gggatttcgc gtgtgatttc
    27061 ttcaggtcct aattttgtat cgcgggcttc tgattcatat tcttcaatat ggatagaagt
    27121 gtatacgtca tcttttacca aacgacggct catgatgatc gcatcttcat agttgtaccc
    27181 ttcccaagtc atgaaaccaa ctaaaacgtt ttggcctaga gccatttcgc cttgttccat
    27241 agatggtccg tctgccagag tatccccttt ttcgactttc tcacccaaat gaacgattgg
    27301 acgttggttg tagcttgttc cggagtttga acgacggaat tttgttacat cgtatttatc
    27361 taatgcaccg ttgtcgcggc gtacgcggat ttcagaagca tcaacgtatt caacgacacc
    27421 gtcatgttta cataacaaag cagctcctga gtcatgcgct gatttgtatt ccataccagt
    27481 accaacccat ggtgcttgag gattgatcaa cggcactgct tgacgctgca tgttggcacc
    27541 catcaaggca cggttggagt catcgttttc caagaaagga atacatgctg tcgcaacggc
    27601 aactacttgt ttaggtgata cgtccatgta gtctacttta tcaatagata cttctaagtt
    27661 ttcactttga gcacgagcca taacaacgtc ttgagcaaat gttccatctt cattcaatgg
    27721 gctgtttgct tgggctacga tgtaatggtc ttcgatatca gctgtcaagt agtcgatttg
    27781 gtcagtaaca cgacctgttt cacggtctac acgacgataa ggtgtttcga taaatccgaa
    27841 tttatttact ttcgcataac tggacaaact attgatcaac ccgatgtttg ggccttcagg
    27901 agtttcgatc ggacacatac ggccatagtg ggagtagtga acgtcacgaa cttcataacc
    27961 ggcgcggtca cgagtcaatc cgccaggtcc taaggctgaa agacgacgtt tgtgtgtcaa
    28021 ttcgccaaga gggtttgttt gatccatgaa ctgtgacaac tgagaagaac caaagaattc
    28081 tttgatactt gccacaactg gacggatatt gatcaattgt tgaggtgtca atgtttcagt
    28141 atcttggatc gacattcttt cacgaaccac acgttccata cgtgctagcc cgatacggaa
    28201 ttggttttgt aaaagttcac cgactgaacg gatacgacga tttcctaagt ggtcgatatc
    28261 atcgacattg ccgatacctt ccatcaagtt caagaaatag ctcattgaag caatgatgtc
    28321 ggctggacga accgttttta cagctgcttc tggatagccg tttccgatca cgtttacttc
    28381 acgttcaggg tctcttggtg aaaatacttt gatgacttgg acagtcattg gatctgtgac
    28441 cacaccgtct tctgatggat agtaagtcac tgaatttagg ccattatcaa tgaaaggagc
    28501 tagtgtttcc atgacttggt gagtcagaac tgttcctttt tcaacgatga tctcgcctgt
    28561 ttctggatca actaatgttt cagctaatgt cagattcaat agacgtgttt tcaaatctaa
    28621 ttttttgttt actttgtaac gaccaacgtt tgctaagtcg taacgttttg gatcgaagaa
    28681 acgagcattc agcaagttac gtgagctgtc tgctgttttt ggttcgcctg gacgcaaacg
    28741 ttcgtaaacg tctttcaaac cttcttctgt tcttgagtcg cttgcgtttt tatgcaagtc
    28801 tttttcgact gtattgcgta atgtttcgct gtcgccgaag atttcaaaga tcgtatcatc
    28861 ggaaccaaat cctaacgcac gaactaatac ggttaaagga atcttacgtg tacggtcgat
    28921 acgtacataa gagatgtctt ttgcatcagt ttccatttct agccaagctc cacggttagg
    28981 gataacagta gaaccgaatc cttcttttcc gtttttgtcg acttttccat ggaaatagac
    29041 acctggtgaa cggactaact gagaaacgat tactcgctct gccccgttga tgatgaatgt
    29101 tccttgttct gtcattaatg ggaaatcacc gaagaatact tcttgtgctt tgatttcgcc
    29161 agtctcgcgg tttgtcaaac gcaatgttac atgtaatggt gcagagtagt ttgcatcatg
    29221 cgcacgagct tctgctactg tatactttgg ttctttcaat tcataatcta caaattccaa
    29281 agatagattg ccattgaagt catcgattgg caaaatgtct tcaaacattt ctctaagtcc
    29341 ctcatctaag aaccattggt aagagtctgt ttgaatttcg atcaaatttg gtaattccaa
    29401 cacttcactg attcttgcga aacttctacg ttcgcgatgt tttccgtatt ttactacgtg
    29461 tccagccaag ctcttcaccc ctctaaaatg tcattcaaaa agactacccg atcaattgtt
    29521 acaataatat ttcaaatatt atttttaggt aacaacagac attttttgcg gcttttaggc
    29581 aaaaaaaaac caaaaataga acattctctt gaaaccttac ttcgtgagct tctacttttg
    29641 tttccttata ttaaagccga aacggacaat atttcgtttc tgccttttct tcatcagata
    29701 gtttttgcaa cttcatatac tacacttatt ttctataaaa gtcaacactt cctggcgttt
    29761 cttctgcttt ttcgcaacat tttcttaatg ttttcaattt tatgttttca attatctgac
    29821 aattcttaat tgacagacct ttttatctcg gttatacttt agaaaattca ttttgtggag
    29881 gaacttctat gcgaaccaac atcaaccaaa tcgcaccaac acaactgaat aacttttact
    29941 ttagctactt tagataggtt tgtattcatc atgatggata caaacgttaa acgacagttt
    30001 gtatctatga tggctaaaga actttgtatt gcagcaaaaa gccacgtaga caaaatgcta
    30061 agtggctgag cagtgaaaat acaaagtaaa agtatcaagc attctacttt ttcaatttat
    30121 tttccgactt ttcaatccat ttggacattt tgtctgaatg gattttttgt ttcccaaaat
    30181 taaggaggaa aaagaaatga aaaaaaatat aatcatcgga ttaggcgctg ccctgctact
    30241 agctttagga ggttgcgcac aaaaagacaa ttccgcagag gcatcagatg gacaaaaaac
    30301 aattggcgta ttgcaacttg tacaacataa ctcgttagat gctgcctata aaggattcaa
    30361 agaaggatta gcagaagaag ggtataaaga aggcgataat ctaacaatcg attatcaaaa
    30421 tgcccaaaac aatcaagaca acctgaaaag tatgagtgag aaactcgtca aagaagatcc
    30481 tgatttgcta cttggaatcg ccactccagc agcacaatct ttattaaatg aaacaaccac
    30541 tatcccgatg actgtcacag cggtcacaga cttggaacaa gcccatttag tcacatccaa
    30601 tgaaaaacct ggcggcaatg tgactggcac gacagatatg gtgccaatcg aaaaacaaat
    30661 cggcttactg ttaaatatcg tgccagacgc caaaacaatc ggcatcatgt ataacaacgg
    30721 tgaagcaaac tctaagatcc aagctgattt ggcagaaaaa gaattgaaaa aagcgggcgt
    30781 caaagtcaaa gtactgacag caaattccac aaatgatgtc caacaagtga cgaaaagtct
    30841 agctaaagat gtagatggaa tctatattcc tactgataac acgttcgcaa gtgcggcaag
    30901 tgttgtcggt gaagtcgcaa aagaaacaaa aacacctgtc gttgctggcg cagttgatca
    30961 agtcaaagac ggcggtctag caacagtagg aatcgactac gaaagcttgg gcaaacaaac
    31021 agggatcatg gcagcaaaaa tcttagacgg caagaatcca agtgaacttc ctgtcgaaac
    31081 agcgaatgat ttggaactgt atgtcaataa agacatggcc aaagcattag gcatcaatcc
    31141 agacagcatc aaagaagctg aataaaacac aggaggattc tcatgacaaa tttgctctct
    31201 cttttcttat catctgcatc gcaaggggtc ttatgggccc tacttgcgat tggtgtatac
    31261 gtcactttcc gtatcttgga cattgccgac ttgactgctg aaggaagctt tcctttaggt
    31321 gcagggatcg cggcagtaag tattacaaat ggctatcatc cattgacagc ttgtcttcta
    31381 ggctttttag ggggtgcggc agcagggctt gtttccggac tgcttcacac aaaattgaaa
    31441 attcccgccc ttcttgcagg gatcatcacc atgactggtt tatattctgt cacatcccgt
    31501 gtgatgggtg cgccgaacat ctctttattg ggtcagccaa cgatctttca ttgggtcgag
    31561 tcattcggca taacaaaaga caacgctgta ctgatcgtcg gtctgctttt tgctttgatc
    31621 gttgtatgtt tacttgtttt gttcttacgt acagaaacag gacttgctat tcgtgcaact
    31681 ggcgataatc tggcaatgag cgaagcaaac gggatcaaca cagataatat gaagatcatc
    31741 ggttatatga tttctaatgg atgcattgct ctttctggct ccttacttgc gcaaaacaac
    31801 ggctttgctg atttaaattc tggtattgga acgatcgtaa ttggacttgc ttctattatc
    31861 atcgcagaag ttttgttacg taaccagcca ctatttctcc gtctcttgac tgtcgtttta
    31921 ggtgcggtca tttatcgttt tattttagcg ttagtcttcg aactgaatgt tgaaccaagt
    31981 gattcgaaac ttgcttctgc tttcgtgcta gtgatctgtc tttctttccc gcagatccag
    32041 caaaaattcc atttacctca aaaaaagaaa ggcggtagtg tcaaatgaat gacgtcttaa
    32101 cattggaaaa tctccatcat acctttgaaa aaggaacgat caacgaaaat catgtcctga
    32161 aaggcattaa tctttcctta gatcccggcg acttcgtgac gatcatcggt ggaaatgggg
    32221 ctggtaaatc tactttgctg aacagcatcg ccggtacatt ttctgtcgat cagggtcaaa
    32281 ttttattgaa tggaaaaaat atcacgaaaa aatctgttgt cgaacgttcg aaatccatca
    32341 gtcgcgtatt ccaagatcct aaactaggga cagccgttcg tttaacggta gaagaaaatc
    32401 ttgctcttgc tatgaaacga ggaaaaaaac gcggcttctt ccgtggtgtc aaaccacaag
    32461 accgaacatt tttcaaagac cagctggttc ggctaaattt ggggttggaa aatcgtttat
    32521 cctcagaaat cggtttgctg tctggaggac aacgtcaagc tattacgtta ttgatggcca
    32581 cattacagcg tccagaactg atcttattag atgaacacac tgcagcgctt gaccctgcta
    32641 cttccaaaac ggtgatggaa ttgacagaaa agctgatcac tgagcagaat ctcactgctt
    32701 ttatggtcac tcatgacatg gaagacgcga tccgctatgg gagtcgactg atcatgctgc
    32761 atcaaggaag gatcgtcgta gatatccagc aagaggaaaa acagcagctc acagtgcccc
    32821 aattattagc gttgttcaaa caaaacagcg gcacggcatt aaaagacgat caagtacttt
    32881 tatcttcata atcagaaaga ggatgggaca aaaaatgaac gcccaccctc ttcttttttc
    32941 tctttccttc tttcgttttt gctttatgta tcaaccgttg tttcttcgaa aactattttg
    33001 ttctctcctt cttcctgata gaatggatgg gaaaggagct tgatgccatg acaacgaaag
    33061 acaaggtact tcaattattg aaaaagacac cagattttct ttccggagaa aagttggcac
    33121 agcaactgga agtttcccgg acaagtattt ggaaagccat caaagaattg gaaaaggcag
    33181 gctatcgttt tgagcacggg cctacagggt atcgttacct gccctctgac gtactagatg
    33241 caaaagaaat ccagcaagag ctacggtcgt ttattcctga tttgaaagta caaacgatgt
    33301 tgacttctga atctacgatg aaagatgcca aactggcagc agctcaagga gattctgttt
    33361 cgaagttatt tgttgctgat acacaagaac aagctcgtgg acgttttgga cggccttttt
    33421 tcgctgaacc tggacgagga atctacatga gtctcttgct ccatccagac aaacggtttg
    33481 atgaattgcc tcaatatacg atcatcgcag ccagtgcctg tgtgaaagcc attgaatctg
    33541 taaccggtcg ttctgcttcg atcaaatggg tcaatgatat ctacatggat ggaaaaaaag
    33601 tctgtgggat tttatctgaa gcagtcagtg atatggaaag cggcaggatc agtcatatca
    33661 tcattgggat cgggcttaat ttttctgttc ctcaaaatca ttttccagct gatctccaag
    33721 aaaaagccat ctctgtcttt cccgacggac aagctagtgt cacaaggaat cagctaatca
    33781 gcaaaatctg gcaagaattg ttcacttatc tttctcaccc agaaaaagcg ttggacttct
    33841 ataaagaaaa atcattcgta ttgggaaaaa ccgtgtcgtt caatcaaaaa ggaacgactt
    33901 atgtcggtct tgcaaaagaa atcggtgatc atggcgaact gatcgtccaa acaaatgaac
    33961 agaagatgag tttgtcttct ggcgaaatca gtctcacatc tatccgtacg caataattat
    34021 cagatttcac aaaaggacac ctgatctcat acagtgtcct tttttctgaa ttctcttcaa
    34081 aagactctcc ttattctatc agctgacagt ttctctatcc tctagaaaaa ggtattctaa
    34141 aaatatctat aaagcatggt acactttctt taaatgaatc aatgcaaaaa acaagagagt
    34201 catcagttta cacgatcaaa agagatagca ggccgcttcc tttttcaatc ttatagatag
    34261 accatgggta acgataaaaa caaaaaagaa cttgcgactt attttgccgt aagttctttt
    34321 ttagctagtg ccttaatctc ttaatcccaa caaacgtctc gcatagatca cctgaccaga
    34381 gtgcatagca gcatcatcaa taatagaaac gagacgcatt cctcgtgtga ctggtggtgt
    34441 ccagttctcg tcaattactt catctagctc ggaaggttcc agccttctta agtaagaaat
    34501 agcaaaatca gcagctcctc gcaagtatcc tagcagatct tctatttgat tagcttggat
    34561 ctgctttgct tgttccagac tatgcttcca atcttgttcg ttatctgcta tcgtcatcgg
    34621 aaaccggctt tcccagtctt gactatgcca aattggagaa gttcctgcta aatcagcaat
    34681 ctggaaatct aattctcgag cggtatgcca agccagccaa gtcattgatt tgatctgcgg
    34741 ggctctatct tccactggaa aacgattggc ctcctcaata gagacgcctt caaacaaacg
    34801 ttcaaaccga tcgtatgccc gatccacact ctcgcatagc atatctaaat aatccattta
    34861 ttttcctcct ttttatttat cctacttact ttttcctaat tctaggatac ctacttatat
    34921 gttactacac acccttattt tttacacttt aacagtcacc atcatcaata gtttggagat
    34981 tgaaagaaaa agatagtgtc gaactatcaa ttgaacaaga agcaacaata tgaacgtttc
    35041 attaatattc tttaaataaa caatgatttt tcaaacgaac agtttaagac taggagaaaa
    35101 agagtataat aggaaaatgt ttgaaaggaa aggaagggga aaaatgaaaa aaagggcaag
    35161 tttactagtc ctagttgctt tgttgttcaa tatcttttcg tatggtgtgg ccgtttcagc
    35221 ggaaacatac attcctaaag accctgggaa tatttataat gatctaactg gtaactatgg
    35281 cttgttagga attgctagtc aattccacgt atttgctaaa aataagacaa ctgtgaatgc
    35341 acatacagac ggaaatatag caacacatga acttgatgca aaaaataatt ttggtacaga
    35401 gcttcatgaa ggtttattga accaagaaat aaattatata caaaaaactg attctttcgc
    35461 taattcttca ggcataccta caggtagcac aagaatgaat aaatttgtcg ttggcagtaa
    35521 cgtggatgta gcacttcaag atggtcatcc tacagtcaat ggatccaggc ttgatcactt
    35581 aactccagat gatttttata aagatcgtgc tgggcatgaa tatattgatt tcgagcagga
    35641 atttgctaaa ttgaatgtag cagcaaatga tcttgcaacg atcactccag ctaaaacata
    35701 tactgctgca gattttccag acatgaacaa tcggacaatc gatttaactg atttatcaga
    35761 taccgggttt ttattggtaa atatcgatgc agaagtgtta acgatgaata cgccacttca
    35821 aatcattaat ccaaatgatc aagtagttgt atttaatgtc atcaacagtt cttctgcatt
    35881 gaacgtacag tcaccaatca aatacaatga tcgttcaaat catgaaacag aagatttttc
    35941 ggatgcgaat atctcttgga attttggaaa tgagatgact gatttgacaa tcagtgctcc
    36001 ttttcaagga acaatccttg cgcctaatgc tactatccgc attactcaaa accaagacgg
    36061 aacgattata ggaacaaatg tgattttaga tgcagctacc aatcgttggg atcctaacga
    36121 aatatttatc agcgacaatg gtacagatac gacagacaca agcgacagta cagatacatc
    36181 taccacaagt gatagctcag attcatcaac ttcaagcgac agtacagata ctacctctac
    36241 cacaagtgat agcacggata catcagcttc aagcgacagt acagatacta cctctaccac
    36301 aagtgatagc acggacacat cagcttcaag tgacagtaca gatactacct ctaccacaag
    36361 tgacagcacg gacacgtcag cttcaagcga cagtacagat actacctcta ccacaagtga
    36421 tagcacggac acatcagctt caagtgacag tacagatact acctctacca caagtgatag
    36481 cacggacacg tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac
    36541 ggacacgtca gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga
    36601 ttcatctacc actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac
    36661 atcctctacc acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc
    36721 gtctaccaca agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa
    36781 caggacgaac tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag
    36841 agcacttcct aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt
    36901 acttgtaatc ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa
    36961 tattcaagat aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta
    37021 tcataaatac aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa
    37081 atttatttac gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta
    37141 agggaaaaga gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc
    37201 aaagcctttt ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt
    37261 tcaacgattt tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa
    37321 taaggtagta gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc
    37381 ccttgacgca tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct
    37441 aaaatatcat cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt
    37501 tttgcgaagc gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac
    37561 agttcagctg tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta
    37621 tagcgatcat ccatctgccc taattcgcca ttcaatactt tttccatact gcgagaattc
    37681 aattggagac ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat
    37741 aaatagtctc ctgcatagac agaaacgaca ttaccaaact gactacggat attaggctga
    37801 ccacgtcgca gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc
    37861 atttcgatag aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt
    37921 gagaacaata gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg
    37981 atggcttgtt cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt
    38041 tctgtcaatt ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa
    38101 aaactccttg tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc
    38161 ctgctcataa tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc
    38221 tgcgatcccg attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa
    38281 catgactgtc catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat
    38341 gaaaccgccg gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac
    38401 caataacatt ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat
    38461 cgttccgcct agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtcttg
    38521 ttttttcatg gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc
    38581 aggcgcaaaa gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg
    38641 tgcaacaagt agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct
    38701 aataaatcag actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat
    38761 gtggcaaaca gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct
    38821 ggtcatcgca atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat
    38881 aatctccgtg ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga
    38941 atgttttgat ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt
    39001 tttgctgaag accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa
    39061 taaaaacatc ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg
    39121 ttctcctttt tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc
    39181 tgtgtcttgc tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat
    39241 tctttgggct tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga
    39301 cagaagtggg caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt
    39361 gtgaaatttc ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg
    39421 ttgtaacaga ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat
    39481 tcctttaatt ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa
    39541 atcttgcatt caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc
    39601 taccgtacca ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc
    39661 caatcgcacg tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta
    39721 cccagtaaaa catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc
    39781 atagccatgt gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca
    39841 tgaatttttg gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg
    39901 tgaaccagtc tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca
    39961 aaccaaaatg tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag
    40021 ctgtggttgc atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc
    40081 atgtccaagg gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg
    40141 gtttgaacac ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac
    40201 catagaaaat acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc
    40261 gagtcacgtt gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat
    40321 aataaccaga acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag
    40381 ctaaaaatcc gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa
    40441 tagaaaccat aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg
    40501 aagccacgat attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg
    40561 gtgtcggtgt tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt
    40621 tatcttcgta gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg
    40681 attctaatcc aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg
    40741 tgtgagtcgg aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga
    40801 ttggtgcatt caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag
    40861 catcatttcg atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga
    40921 tttcgtttgg atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc
    40981 caatcatttc aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac
    41041 gcagttcatc atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa
    41101 tccttacaga atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac
    41161 caaagtcatt cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta
    41221 atttggtctt gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt
    41281 gtacattctt ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta
    41341 cacgtccgcc agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga
    41401 tcagagtaat tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa
    41461 caccggcata tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc
    41521 ttatagacta tctatataat gaatatatga taattctttt agtttgatac ttattacaca
    41581 atctccatat attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca
    41641 aattttaaaa taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac
    41701 atgggttatt tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa
    41761 tcacaaagaa aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac
    41821 gttttgtaac tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg
    41881 cagatgacaa cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg
    41941 caaaaagcac aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca
    42001 catataaatt agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg
    42061 taaaagacgg caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa
    42121 aaacaaaaga tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa
    42181 aatacattcc tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag
    42241 tcgtaactgg agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc
    42301 aagctgctca agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag
    42361 acggcactta caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa
    42421 tgacagttgc tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta
    42481 aatcaaaaca agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac
    42541 caaaaactta catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg
    42601 gctcacctgc taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca
    42661 tgtacgcaca acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag
    42721 ataatatcgt aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac
    42781 gatagccaga ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa
    42841 aaaactacta ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag
    42901 caactcagca aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc
    42961 atattctgat gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg
    43021 caaagaatca gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac
    43081 gatcaatcaa aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt
    43141 aaaagtttct gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc
    43201 tcaaggcgga ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga
    43261 tgacgccaga aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca
    43321 taagatcgaa ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat
    43381 cgatttaggt gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa
    43441 acaaggagtg accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag
    43501 cccaagaggc gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg
    43561 atctgtttta ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga
    43621 gcgttattta gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta
    43681 tccgttcgac aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga
    43741 cgggttgtct acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag
    43801 cgaattgaat aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac
    43861 cgatccaatc aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg
    43921 ttctgaacta aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga
    43981 aatacgaaca aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc
    44041 tttttttcat gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt
    44101 tgatttagcg actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt
    44161 atataagtat gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa
    44221 catgatttta gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac
    44281 gggttggctt ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt
    44341 cggaccgatt cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg
    44401 ccttggaatt tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct
    44461 gacagtcaac ttttcatctg gacaatttga tttggtagga aatctttggg ctatagcagc
    44521 aatcgtatta gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa
    44581 tttgcgggat cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg
    44641 acgtcctgcg ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt
    44701 aatggggttg ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc
    44761 aattgtgaag aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag
    44821 ctattccatc aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac
    44881 aatcattatg caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa
    44941 gtaataagaa cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta
    45001 ccgcagatgc aagcttttga acaccgttta tca
//
LOCUS       DADVXM010000014        43687 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.015, whole genome shotgun sequence.
ACCESSION   DADVXM010000014 DADVXM010000000
VERSION     DADVXM010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 43687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.015"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(328..2709)
                     /locus_tag="KB927_000871"
     CDS             complement(328..2709)
                     /locus_tag="KB927_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBB6839806.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGAGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2699..3346)
                     /gene="recU"
                     /locus_tag="KB927_000872"
     CDS             complement(2699..3346)
                     /gene="recU"
                     /locus_tag="KB927_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBB6839807.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3410..3949
                     /locus_tag="KB927_000873"
     CDS             3410..3949
                     /locus_tag="KB927_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBB6839808.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            4039..4458
                     /gene="gpsB"
                     /locus_tag="KB927_000874"
     CDS             4039..4458
                     /gene="gpsB"
                     /locus_tag="KB927_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBB6839809.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4480..4847
                     /gene="rnpB"
                     /locus_tag="KB927_000875"
     ncRNA           4480..4847
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KB927_000875"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            5056..6222
                     /locus_tag="KB927_000876"
     CDS             5056..6222
                     /locus_tag="KB927_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBB6839810.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6268..7764
                     /locus_tag="KB927_000877"
     CDS             6268..7764
                     /locus_tag="KB927_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBB6839811.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7845..8528
                     /locus_tag="KB927_000878"
     CDS             7845..8528
                     /locus_tag="KB927_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6839812.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            9173..10363
                     /locus_tag="KB927_000879"
     CDS             9173..10363
                     /locus_tag="KB927_000879"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBB6839813.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            10465..11418
                     /locus_tag="KB927_000880"
     CDS             10465..11418
                     /locus_tag="KB927_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBB6839814.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            11487..12836
                     /locus_tag="KB927_000881"
     CDS             11487..12836
                     /locus_tag="KB927_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6839815.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVIAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(13019..13342)
                     /locus_tag="KB927_000882"
     CDS             complement(13019..13342)
                     /locus_tag="KB927_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839816.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            13471..14634
                     /locus_tag="KB927_000883"
     CDS             13471..14634
                     /locus_tag="KB927_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBB6839817.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            14704..16053
                     /locus_tag="KB927_000884"
     CDS             14704..16053
                     /locus_tag="KB927_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6839818.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(16098..16529)
                     /locus_tag="KB927_000885"
     CDS             complement(16098..16529)
                     /locus_tag="KB927_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6839819.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            16917..19559
                     /gene="alaS"
                     /locus_tag="KB927_000886"
     CDS             16917..19559
                     /gene="alaS"
                     /locus_tag="KB927_000886"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBB6839820.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            19759..20355
                     /locus_tag="KB927_000887"
     CDS             19759..20355
                     /locus_tag="KB927_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6839821.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            20477..21625
                     /locus_tag="KB927_000888"
     CDS             20477..21625
                     /locus_tag="KB927_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6839822.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(21663..22076)
                     /locus_tag="KB927_000889"
     CDS             complement(21663..22076)
                     /locus_tag="KB927_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBB6839823.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            22155..22586
                     /locus_tag="KB927_000890"
     CDS             22155..22586
                     /locus_tag="KB927_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBB6839824.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(22685..22918)
                     /locus_tag="KB927_000891"
     CDS             complement(22685..22918)
                     /locus_tag="KB927_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBB6839825.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            23101..24771
                     /locus_tag="KB927_000892"
     CDS             23101..24771
                     /locus_tag="KB927_000892"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBB6839826.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            24918..25304
                     /locus_tag="KB927_000893"
     CDS             24918..25304
                     /locus_tag="KB927_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839827.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            25291..25989
                     /locus_tag="KB927_000894"
     CDS             25291..25989
                     /locus_tag="KB927_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6839828.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            25994..26458
                     /locus_tag="KB927_000895"
     CDS             25994..26458
                     /locus_tag="KB927_000895"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBB6839829.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            26455..27366
                     /locus_tag="KB927_000896"
     CDS             26455..27366
                     /locus_tag="KB927_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6839830.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            27601..28140
                     /gene="pyrR"
                     /locus_tag="KB927_000897"
     CDS             27601..28140
                     /gene="pyrR"
                     /locus_tag="KB927_000897"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBB6839831.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            28154..29437
                     /locus_tag="KB927_000898"
     CDS             28154..29437
                     /locus_tag="KB927_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBB6839832.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            29450..30376
                     /locus_tag="KB927_000899"
     CDS             29450..30376
                     /locus_tag="KB927_000899"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBB6839833.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            30395..31675
                     /locus_tag="KB927_000900"
     CDS             30395..31675
                     /locus_tag="KB927_000900"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBB6839834.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            31680..32756
                     /gene="carA"
                     /locus_tag="KB927_000901"
     CDS             31680..32756
                     /gene="carA"
                     /locus_tag="KB927_000901"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBB6839835.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            32761..35946
                     /gene="carB"
                     /locus_tag="KB927_000902"
     CDS             32761..35946
                     /gene="carB"
                     /locus_tag="KB927_000902"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBB6839836.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            36000..36776
                     /locus_tag="KB927_000903"
     CDS             36000..36776
                     /locus_tag="KB927_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBB6839837.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            36773..37705
                     /locus_tag="KB927_000904"
     CDS             36773..37705
                     /locus_tag="KB927_000904"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBB6839838.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            37702..38418
                     /gene="pyrF"
                     /locus_tag="KB927_000905"
     CDS             37702..38418
                     /gene="pyrF"
                     /locus_tag="KB927_000905"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBB6839839.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            38425..39054
                     /locus_tag="KB927_000906"
     CDS             38425..39054
                     /locus_tag="KB927_000906"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBB6839840.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            39042..39356
                     /locus_tag="KB927_000907"
     CDS             39042..39356
                     /locus_tag="KB927_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839841.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            39394..40035
                     /locus_tag="KB927_000908"
     CDS             39394..40035
                     /locus_tag="KB927_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6839842.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            40078..40770
                     /locus_tag="KB927_000909"
     CDS             40078..40770
                     /locus_tag="KB927_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBB6839843.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            40767..41669
                     /locus_tag="KB927_000910"
     CDS             40767..41669
                     /locus_tag="KB927_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6839844.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(41827..43533)
                     /gene="efbA"
                     /locus_tag="KB927_000911"
     CDS             complement(41827..43533)
                     /gene="efbA"
                     /locus_tag="KB927_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBB6839845.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        13997 a         7700 c         9486 g        12504 t
ORIGIN      
        1 agccttcttt caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa
       61 tgggattatt aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta
      121 taaacaagta aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt
      181 taagctaaat gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat
      241 acagcttggt acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc
      301 acgcttgtag acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga
      361 tggtgtatgg tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg
      421 aggagcagat gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga
      481 agacgctggc tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc
      541 gctttgacta gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt
      601 ctggacatag ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt
      661 atattgatct ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca
      721 gtctgtattt gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc
      781 tacgtgtgac gattctgaag tgacaggtgt cattttttta ttgtaacctg tccacacgga
      841 aatcgaataa tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat
      901 accaagtttt gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata
      961 taacccagcg atttgcgcat tcgtaccagc tccttcagtg atcgtatctt ttaaaatgtc
     1021 tgtgatcata taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc
     1081 ttctgttccg tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc
     1141 attggcgaaa gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc
     1201 atcttgttct tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat
     1261 cccaagattt tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac
     1321 tgctggaaca ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg
     1381 attatcccag tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat
     1441 agtttttcca gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt
     1501 catcgtagaa ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc
     1561 ttctgcgatg tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag
     1621 ggtggaggca acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat
     1681 atcatatagt ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt
     1741 gtagacattc ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc
     1801 gacgatctta gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac
     1861 attaacagct tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa
     1921 aacagtatct cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg
     1981 ggcttgaggc atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt
     2041 accaaagtac atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt
     2101 atttacgtag taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat
     2161 ccacgcttct tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga
     2221 aagtttgatc aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt
     2281 agagagggca gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg
     2341 atcttctacc gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt
     2401 ttcacgcttt tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga
     2461 agatacggta gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca
     2521 gaaaagtcct acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat
     2581 cttgataaat aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt
     2641 cttcttcaca ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc
     2701 atttgccatt cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt
     2761 ccaaataagg aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca
     2821 aagataaagg tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat
     2881 gaacactatt caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga
     2941 ccccattttg ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa
     3001 agggaaaaga tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat
     3061 agacgccatt atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag
     3121 cacttctctt aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa
     3181 ccgccaaccc gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca
     3241 tcccccgatt gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag
     3301 aggcattctt ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc
     3361 ctaggccaca ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc
     3421 aaaagtaatc tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga
     3481 tcctaaaatc caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga
     3541 agggctggaa tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat
     3601 agtagcggaa ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc
     3661 tgattttggt aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt
     3721 agcagattat gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa
     3781 tcacactcgt tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt
     3841 ccctggaaaa acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta
     3901 cgaaattcgg ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg
     3961 tttgatttat caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg
     4021 aaaactagag gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa
     4081 gaattcaaaa caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat
     4141 atcatcaaag attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat
     4201 cgattgagtg caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg
     4261 caacaaacag aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg
     4321 tcaaatcttg aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa
     4381 ccagcacaac ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa
     4441 aaaacacgtc aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct
     4501 gacttgatca ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt
     4561 gcttagcgaa accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg
     4621 cttcggctat gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc
     4681 atccggtgga acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt
     4741 ttgtctggaa gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt
     4801 tgttttttct ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc
     4861 agggaattag gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc
     4921 tatttttcaa tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt
     4981 tattcggaat ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa
     5041 ataaggagat tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc
     5101 gggctagaag cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag
     5161 aacggacgtg cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta
     5221 cgtacagcag atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa
     5281 ttgtttgaaa acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt
     5341 cctgtagctg gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc
     5401 acaaaaaaag caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca
     5461 ctgacggaaa ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg
     5521 gtaactctgg atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt
     5581 ggagcaccat tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa
     5641 gaccgtccat tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta
     5701 ataggccata atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg
     5761 ttcagtcaag aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat
     5821 attgaattag atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc
     5881 aatgcagaag aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac
     5941 ttcaaaacgg ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta
     6001 ggagaagaag aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta
     6061 aaaacatgga gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa
     6121 aaagcaacca aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat
     6181 tggggaactc gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat
     6241 tcaattggat gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa
     6301 gaaatcaatc ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg
     6361 cctgaaaaag ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt
     6421 tcaaaaaaaa tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa
     6481 gaattgtcgg aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa
     6541 catcgcgtac cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga
     6601 caatggcaaa aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa
     6661 aatattgaat taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat
     6721 gatgttttgc tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt
     6781 gatcagctta aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa
     6841 cctgaaacag actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg
     6901 aaagtaatcg aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac
     6961 ccatttatga ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca
     7021 gatttcaaaa tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa
     7081 gacatcgatg ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat
     7141 gaatcacaat cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag
     7201 caatatcctt tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa
     7261 ttttatcgtt cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg
     7321 acttaccctc tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg
     7381 gtagatgttg ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata
     7441 cgaccaacaa atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt
     7501 ggttattttc cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg
     7561 cagcaagaaa tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac
     7621 tggatgtcag agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg
     7681 gatgcaacac atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat
     7741 tttaatgtat atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat
     7801 ctatagatgt tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag
     7861 tgatcgctga ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc
     7921 ataccaaaag agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc
     7981 gctttgtgac gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa
     8041 atgagaacga ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg
     8101 aacagatctc gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg
     8161 aagcggccga actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat
     8221 taggagcaat cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt
     8281 ttgatcctga actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga
     8341 cagtgatcaa tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt
     8401 acggatatga agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt
     8461 ttctggaatg gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca
     8521 aaaaatgatg gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg
     8581 taaaagttac ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga
     8641 gtcacaagga acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga
     8701 ttcggaattg gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg
     8761 tcacagtcct tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa
     8821 ttaaaaattg ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata
     8881 aataaattaa atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt
     8941 gttgtattta tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat
     9001 actatataag tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt
     9061 ctcataatca gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca
     9121 cgatatatgt ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc
     9181 caaagaacta acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata
     9241 caatacgatc gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa
     9301 gatgatcaat ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa
     9361 agcatgtatt gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa
     9421 tggttcgctg aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga
     9481 agcagcaatc gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat
     9541 gacaaaagaa gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg
     9601 ccgcttatcc ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa
     9661 aaaagcaaag gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg
     9721 tgttttctcc atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa
     9781 atatggactg atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc
     9841 aggaaccgtc aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc
     9901 gaaagctata ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt
     9961 gaaagctaga agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc
    10021 tgcattggct tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga
    10081 aaatgctaat tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga
    10141 aacacctatt actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa
    10201 gctgatcgaa catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac
    10261 aggcaggatc agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt
    10321 agcagtttat caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc
    10381 gtctatttaa aattagagaa catgttcacg catatattgt taatcatctg aagatagtag
    10441 taaaaaagat cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa
    10501 attggttcag agttgatcac acggctacgt caagaactag gcagtgaaaa tgtcattgcg
    10561 acagatatac gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta
    10621 atggattacg aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat
    10681 ttggctgctc ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac
    10741 gtgactgggc tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg
    10801 ccaagttcaa tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact
    10861 cttcagcgtc ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat
    10921 tattattatg tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct
    10981 tatgcaacct tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca
    11041 atcaaagaag gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat
    11101 atgccagatg cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt
    11161 catcgaaatg ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct
    11221 attcaaaaaa tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca
    11281 atagcagaat cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt
    11341 tcgccgaaat acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa
    11401 ttggtagaga cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt
    11461 ggctatggta tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag
    11521 taaaaataga aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta
    11581 tgggcacagt gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag
    11641 gatccgccag tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag
    11701 gactaacagg agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata
    11761 tcgaacggat ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt
    11821 attttccagc aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat
    11881 ttggtctttc ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt
    11941 tgatcaattt tttaggttct aaagctggag gggcttttca gtcgattacg cttgtctgca
    12001 agcttattcc tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact
    12061 tccaactgtt tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg
    12121 gcttgctagc aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag
    12181 aattgaaaaa gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca
    12241 tgatcgttta tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg
    12301 caggaaacag caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa
    12361 gactggtcac agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta
    12421 ctggaatgcg tctcccttat gttattgcaa aagaaaacaa cctgcctttt agcaagctct
    12481 ttgctaaact tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca
    12541 tcgctattgg catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg
    12601 tcatttggat tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac
    12661 ctgatttgtt tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca
    12721 ttggagggac ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg
    12781 ggatagtatt gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa
    12841 aacattcgaa ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga
    12901 ggagtacgtg gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt
    12961 gtctacgatg aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt
    13021 actttgattt gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca
    13081 agcaaccaga aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag
    13141 acaaagcatg tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat
    13201 tgaagactag catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag
    13261 ttctttttct tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa
    13321 aaacaaagta catattcagc atctcgacac cccctttgtg tttatcttac tttactttga
    13381 aagaaatgag aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa
    13441 gagagataca aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt
    13501 gcgctgattg tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa
    13561 tatcgaaagt atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt
    13621 tatttattgt gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc
    13681 caaatgacag ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac
    13741 aacacggtat tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta
    13801 tttttggaac cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat
    13861 tatttccggc tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt
    13921 gaattgacgc agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat
    13981 gtgaatgatt tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta
    14041 tttacattta tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag
    14101 actgtctcat tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt
    14161 attaatttgg tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct
    14221 catatctggt ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc
    14281 aatggatgga cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa
    14341 cgaatttctt taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt
    14401 ttaagctggt tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg
    14461 cagatgagtg cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta
    14521 aatatcttgc tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac
    14581 acatatactg ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc
    14641 aaaaacgctt tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca
    14701 cgaatgaata attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca
    14761 aagggcttca aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga
    14821 aaaaatatca ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct
    14881 ttgtttgaaa aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt
    14941 agggaactag ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg
    15001 gagatccgtg tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg
    15061 catcaccaac agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat
    15121 gaacaagcgc tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca
    15181 ttggatatgg gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg
    15241 cagtttttag ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac
    15301 atggaaaatc caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa
    15361 aattggctga tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca
    15421 attggtcatc cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt
    15481 gccgattact tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca
    15541 agagagagaa aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg
    15601 actgatttag ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa
    15661 attccagaag atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta
    15721 aaaggaacgg ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa
    15781 aaattgggcg tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac
    15841 gatcgtaata gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt
    15901 ggtcttgtga agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg
    15961 gcaattgcag aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact
    16021 gctcgtaaaa ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt
    16081 gtcacaatct cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct
    16141 tcaataaaag gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc
    16201 atttcagcta ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct
    16261 tcaagcaact gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc
    16321 ggcttgaagc aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga
    16381 tcaagaaata gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca
    16441 ggaatccctt gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc
    16501 cattcatccg ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat
    16561 gtattgattc ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga
    16621 aaataaaaat tgagatattg acagtgatca atagaatgcg tatactaatt aagtacgaaa
    16681 aggatatgat ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag
    16741 tcactaatca aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt
    16801 atcgagttta agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc
    16861 gtccttggct gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga
    16921 aacaattaag tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaaggac
    16981 atacgattga acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca
    17041 actctggtgt tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa
    17101 gaatcacaaa tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag
    17161 cacggcacca tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa
    17221 atgaagccat ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc
    17281 cagaaaaact ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg
    17341 aagaagttgg cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg
    17401 gtgcaggccc atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg
    17461 atttagcaga agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa
    17521 tctggaactt agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc
    17581 ctcataaaaa cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg
    17641 cgtcaacgaa ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa
    17701 gcaaacaagt aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag
    17761 atcatattcg cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga
    17821 gagggtatgt cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta
    17881 ttgaacaagc attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt
    17941 atcctgaagt acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac
    18001 gtttcaatga aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa
    18061 aaaacgaaaa cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg
    18121 gcttcccggt agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg
    18181 ctggttttga aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg
    18241 aaaaatcaat gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca
    18301 ttggatacac agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc
    18361 ttttgaatga agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg
    18421 cagaaatggg tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg
    18481 tagcagttgt tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag
    18541 taaaagcacc aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca
    18601 atcggatcat caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac
    18661 ttggcgagca tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact
    18721 ttacccactt tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg
    18781 aaaaaatctg ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa
    18841 acatgggtgc aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata
    18901 ttggcggctg gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg
    18961 gaatcttcaa aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg
    19021 taacaagtaa agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag
    19081 caacaattgt taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac
    19141 agcaagtaag agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac
    19201 aagctggtga tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac
    19261 aagtaaaagt gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa
    19321 atatttcaga tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg
    19381 caatgacgaa agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg
    19441 caccgaaagt aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa
    19501 atcctgctgg tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg
    19561 gcgtttacgt ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg
    19621 cgaagacaaa caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat
    19681 ggtcggattc ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa
    19741 ataaaaaggg gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg
    19801 atcttgttag caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta
    19861 ggattcatta gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc
    19921 ccaaaagatg gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat
    19981 gccatgccaa caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt
    20041 cccagagtac ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaat
    20101 aaatcaataa cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc
    20161 ttagtgttag gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta
    20221 gactctgctc ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa
    20281 gcaataggtg cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg
    20341 ttgaaaccag aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag
    20401 gaagagagga gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact
    20461 agaaggggta aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca
    20521 gcggacaaaa aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt
    20581 tgtctctaag ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt
    20641 gaacagtcta tcagatactg cttcatccat attgactttg atcggattta aaattgctgc
    20701 aaagccagca gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt
    20761 atttgtttcg atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa
    20821 aatcatccat ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc
    20881 catctttttg aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc
    20941 tgaaacattg agagctacag caacagatag ttataatgat gtctttacta cactggctgt
    21001 attgctttca gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt
    21061 tgctttagca ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga
    21121 actattagga agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc
    21181 ttgcgatgat atacttggct atcatgattt attggtgcat aactatggac ccaataaacg
    21241 ctttgcatca gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat
    21301 tattgatctg atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt
    21361 ggatccaatg cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat
    21421 tcttcttgaa acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa
    21481 aacgctgcaa tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga
    21541 aagaatctta cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt
    21601 tgatcacaat tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta
    21661 atttaaagag tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct
    21721 gctcctttat ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga
    21781 agttcttgga ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg
    21841 accgtagaaa ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg
    21901 tttttcttta gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc
    21961 cctatagaaa gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca
    22021 cctccactag gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa
    22081 agagattctc ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg
    22141 tgagaggtta gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca
    22201 tctattggtc attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca
    22261 caggtcctta ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag
    22321 gtttgcggcg ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt
    22381 ggaaagaccg agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg
    22441 tgcaaatgat gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc
    22501 aagtagtcct ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc
    22561 cttatacgaa aaaaagaaaa agctaatttt aaaaatcaga acctaaaaaa acgaattttt
    22621 acaggaaaag aaaagagtga gacgtacggt tcatcccgtt tagcgtctca ctctatttgt
    22681 ttatctattc atgcatacta gtatcggtag tctgaacgtt gcctttcttg acatgggcag
    22741 cttgtgttcc tcgattccct tcgatgatct caaattcgac cacttgattt tcttccaaag
    22801 ttttgaatcc ctcttcttca atcgcagtaa aatgtacaaa aatttcttct gtgtcatcat
    22861 aactgataaa gccgtatcct tttttgttgt caaaccattt tacaattcct gtggtcaaag
    22921 cactcacgac ctttctaaag tctgatcata gccttcatta taaagagtat ttataagtac
    22981 gtcaaataaa ttaaaaacct gtaattttat gttttttttc tgaataaaaa aaggtataat
    23041 tggcatatct taacaaagaa gatattttgt tgaataaagt tcgtgaaaag gggtaatcaa
    23101 atgaagaatg atctgcaaat ttcacaagaa acagagctag aaccgattgt tgaagtggct
    23161 agtaaattag atcttaagga agacgatttg gaactgtatg ggaaatataa ggcgaaaatc
    23221 aatttttctg gaatcaatcg atcaaaggat aacgctgagg ggcatttgat cttagttact
    23281 tccatcaatc caacaccagc tggcgaagga aagtcaacga tcactgtagg gttaggagac
    23341 gcgctcaata aaatcaataa aaaatctgtt attgcattgc gagaaccctc acttggtcct
    23401 gtgatgggaa tcaaaggtgg tgctgcaggc ggaggatatg cacaggtatt gcctatggaa
    23461 gatatcaact tgcattttac tggtgacatg catgctatca caacagctaa taatgcatta
    23521 tctgctcttt tagataatca tattcatcaa ggaaatgaat tgaacatcga tgcccgccga
    23581 gtgatttgga aacgggtagt cgatctcaat gatcgtgaac tgcgtaaagt aattgttggc
    23641 ttgggtgggc caatccaagg tgttccaaga gaagatgggt ttgatatcac agttgccagc
    23701 gaaatcatgg ctatcttgtg tcttgcggca gaccttgaag atttaaaggc tcgtcttgca
    23761 aggatcgttg tcggctatac atttgaccgt cagcctgtga ctgctggaga cttgaaagca
    23821 gaaggcgctc tggcattact gctgaaagat gcaatcaagc cgaatcttgt acaaacaatt
    23881 tacggaacac cagcttttgt ccacggggga ccgtttgcca atatcgctca tggctgcaat
    23941 agtattttag ctaccaagac agcattgaga ttagcagatt acgttgtcac agaggcagga
    24001 tttggtgcag atcttggcgg agagaaattt ttagatatca aagtacctaa cttgaaaaaa
    24061 gcgccggatg ctgtggtgat tgtcgccact gtccgtgcat tgaaaatgca tggcggaatg
    24121 aaaaaagatg aacttaaaaa tgagaatctt gatgctttga aagtaggttt tgcaaattta
    24181 aagcgccata tacgtaatat ggaacaatat cagctacctg tgatcgtcgc aatcaatgaa
    24241 ttcgtaacag atacagacaa tgaactcaca ctgttggagc acttgtgtga aaatcagggg
    24301 attcttgcca agagagcgag tgtatgggca gatggagcag aaggcggcgt tgatttagca
    24361 aaagctgtag tacgattgat tgatagaaaa gaagctaatt acaagccatt ataccgccta
    24421 gaagaaacga tacaagaaaa gacagaaaca atcgtcaaga aaatttacgg aggaaatggt
    24481 gttgttttca gcaaaaaagc gcaaaaacaa atagaagagt ttacgaagaa tggatgggac
    24541 aaactgccga tttgtatggc aaaaacacag tattcatttt ctgatgatcc ttcactgcta
    24601 ggtgcaccgg aagatttcac catcacgatc cgcgaaatca tcccaaaatt aggggcagga
    24661 tttttagtag ccttgactgg agatgttatg acgatgcctg gtttgcctaa aaaacctgct
    24721 gcattgaata tggacgtgac aaatgacgga gaagtgttgg gattgtttta agcttgatta
    24781 taatctacca tcgaaggagc tgtattttga ctacagcttc tttttttaga cgatagggaa
    24841 ttaattttgt ttacactagg atcattcttt ttctttattg tattttgagc tatactaaag
    24901 cataatagga gggtatgatg aaaacgacat ttataagaaa aaccggtttt tacggtatgg
    24961 gtagctcgat tcagctaaga atcaacaatg aaaaacgcag tgttctcagt catgaacaaa
    25021 agataacgct tgatctggaa gtgcccttta cgatgcaggt caccttttat tggctaaaaa
    25081 gccccgttta tacagtgaaa gaagcaaagc ctgcttatgt gatcacaatg aattacttga
    25141 ttcttcaaat ctatccgttt ttatttctag caactgggtt gggggccgtt ttcctacaaa
    25201 atttattttt cagttttttt gcagttattg tgttgattgc gttctttttc tatataaaaa
    25261 accgggcata tttgatcaag gaggaaaatt atggcaaact ctgatctttt tttaatcagt
    25321 ttcaatcgaa tcgaaaaatg gatgagagac gagatgggaa atgcacgaaa tatgggattt
    25381 accgaacttg tcagacgcct agctcaaaga aaacaattaa tgatcagaaa atacgaagat
    25441 gatcttttac agcttgctca gttaaggaat gcgatcgtcc atgatcggat cgcagtcgat
    25501 tttgtcattg cagagccaaa tgattggaca gtcaagcgaa tccagctgat cgaacaagaa
    25561 ctgattcagc ctgaaaccgt gctgcctcga tttgcaaaac gtgtaacagg ttttgaacaa
    25621 gatcttccgt tacttgaact gttaaagata gtagcagaaa aaaggtattc acaatttccg
    25681 ttatacaata aaggaaaatt tgtagcattg attactttac gtaatatcgg gttttggcta
    25741 gcaaaagaaa gccaaaaagg tccggttgat ttaacaaata aacgagcgtt ggatttgatc
    25801 atccaaaacg gaaagtacac aaattatcat tttgttccag ctaaaacaca tatttacgag
    25861 gttgaagcga tgtttcgtga gcaagggact ttggaagccg tacttatcac taaagatggg
    25921 aatcccgatg gtaatctgct cgggatcgta cgacctcgtg atatttataa acaaatagaa
    25981 aaggattgat tttttgttaa ttatttattg gatattcagc gctttgctag taggagtgga
    26041 tcagttggtc aaatggtgga tcactgataa tctagcgctt ggagagacga aaaatcttat
    26101 accaggtatt ttgtcactga atcatattcg aaacactgga gccgcatgga gtatgctaga
    26161 agggaagatg tggttcttta ctatagtgac actcattgca gtcgttgtga ttctcacatt
    26221 gatgattaaa aatcgtgaaa aaggtaatcg ctggttcatg attggattga gtttgattct
    26281 agctggtgcg attggcaatt ttatcgaccg tattcgtctt ggctatgtag tagatatgtt
    26341 ccagacagat tttatgagct ttccgatttt taacgtagca gatgtgacac ttgtatgtgg
    26401 agtgatttgt atgttaattt atattatttt agatgaaaag gatcaaagaa aaaaatgaca
    26461 gaacttaaaa cgacgattca ccatgaatct ggtaggatcg ataaagtatt gactaattta
    26521 ttcaccgatt acagtcgttc gcaaattcag ctgtggctga aaaatggagc ggtttctgtc
    26581 aatggacagc cagtcaaagc aaattacaaa gtaaaacaag gagacgagat tactgtcttg
    26641 atccccgaac cagaaacatt agatgtggtc ccagaaaata tcccgttgac gatcgtttac
    26701 gaagatgaag atgtagcggt gataaacaaa cctcaaggaa tggtcgttca tccttcagca
    26761 ggtcatacgc atggcacaat ggtcaatgcg ctgatgtacc atatcaagga tctttctacg
    26821 atcaacggcg ttattcgtcc aggtattgtt caccgaatcg acaaagatac ttccggactg
    26881 ctaatggttg ccaaaaatga ccaggcacac gaatcattag ctcagcaatt aaaagataag
    26941 acctctttgc gcaaatatgt tgctttagtc catggagaga ttcctcacga aaaaggaacc
    27001 atcaatgcgc caatcggccg ttcgaaggaa aaccggaaaa tgcaggcgat aagagaagat
    27061 gggaagtcgg ctgtcacaca ttttactgta ttggaacgtt tcgaaggatt tactctggtt
    27121 gaattaaaac tagaaaccgg aagaacacac cagatccgtg tgcatatgaa gtatatcggt
    27181 tatccgttag ctggagatcc agtatacgga ccgaagaaaa ctttgaaagg caatggtcag
    27241 tttctccatg cgcaaatgtt aggttttacg cacccgacta caaacgaaaa gatgatcttt
    27301 gaagcacctc ttccagaagt ttttgaaaaa actttagaaa aattaagaaa aaacattgca
    27361 ttttaattta gataacggta tagtaattaa caacgaaagc ataaaactta atagaattcc
    27421 tttaagttta gtcccgtgag gctaagaagg gtgggagcaa ggatacgtat ggtgcgccat
    27481 aagtagattg ctcattgaca tagtatagct atcagtgtat cagtatacgc tcagtctaaa
    27541 cattcctcct gtcctcttag ggcaggagtt tttttatgca aaaaagtagg gggaatgaaa
    27601 atgcaagcaa aagaagtagt agatcaggta accatgaagc gagcattgac tcgaattact
    27661 tatgagatta tcgagagaaa ccatagtatc caagatatcg tattggtagg tatcaaaaca
    27721 cgaggaatct acattgcatc aagaattgcc gaacgcctga agcagctaga agatatcgat
    27781 attcctgtag gagaactgga tatcacttta taccgagatg acaaaaaaga aaatccagaa
    27841 gaaccggaac ttcattcttc tgacatccca gtttccttag aaggaaaaga agttattttg
    27901 attgatgatg ttttgtatac aggacgaacg attcgagcag caatggacgc agtaatggat
    27961 tttggcagac caagaaaaat ttcattagca gtcctggtcg atcgtgggca tcgagaattg
    28021 ccaatccgtg cagattatgt tgggaagaac attccaacat ctcgggcgga agagatttta
    28081 gtagagatgc aagagcttga tggacaagat cgcatcatga ttttgaaaga ggaagattag
    28141 aggagagaga aacatgtcgg agaaaaaagg atttcataat gatgacgtgg tgttagatat
    28201 ccacgatcgc ccaaccccag gacattgggt aggattaagt ttacaacact tgttcacgat
    28261 gttcggagca accgtgttag tccccatctt agtaggtatc gatccaggta ttgcgctagt
    28321 cagttcagga ctaggtacat tggtgtactt atttactact aaaggaaaga tacctgcgta
    28381 cttaggaagc agcttcgctt tcattgcagc gatgcagctt ttgatgaaaa cagatggtta
    28441 tccagcgatt gcacaaggag cagtcacaac tggattagtc tatttgattg ttgcgctgat
    28501 catcaaaaag atcggttcag catggctgga taaaatcttg cctccaatcg tcgtcggtcc
    28561 agtcatcatg gttatcgggt tgggacttgc ggcaaatgca gcaacaaatg ctatgtataa
    28621 tcagggcacg tatgatttca agtatattgc tgtagcgctg atcacattag gattaacaat
    28681 tttcttcaac atgtggctaa gaggttttct cggattgatt ccgattttac taggtattat
    28741 tagcggatac atcgtagcct tgctgtttgg aatcgtggat actaagccaa tcgtagacgc
    28801 tgcctggttt gctgttccta actttgagat tccctttgta caatatgaac caaagctata
    28861 tcttggagca atcacaacaa tggcacccat cgcttttgtg acgatgacag agcatatcgg
    28921 ccatcttatg gtattgaata aactaactaa acgtaatttc tttgaagaac cgggtcttca
    28981 taagacgttg acaggtgatg gattagcaca aatcgtggca gcctttgtcg gaggtcctcc
    29041 tgtaacaagt tacggtgaaa acattggtgt tctggctatc acacgtgtcc atagcgtgtt
    29101 tgtgatcggt ggagctgcag tatttgcagt cattttagga ttcgtaggaa aattaagcgc
    29161 tttgatttta agtatccctg gaccagtcat ctcaggaatc agttttatct tatttggagt
    29221 aattgccgca agtggaatga agattttaat cgagaacaaa atcgattttg ataaaaagaa
    29281 aaatctgttg attgcttcag ttatcttagt agtaggaatt ggcggactcg tctttgaagt
    29341 aggcacattt acattgtcgg caatggcatt agcaactgta cttggcatca ttttaaatct
    29401 tatcttacca gaaacttcac gaagcgaaga aaactaagga ggaaacatta tgatcatcaa
    29461 atcagaacgt atcagcttaa agcatttatt gaccgttgag gcacttactg atcaagaagt
    29521 tatgggcttg atccgcagag ggcaggaatt caagcaaggt gctaattgga ctccgcaaaa
    29581 gcgccagtac tttgctacaa acctcttttt cgaaaatagt actcgcacac ataaaagctt
    29641 cgatgtagcg gagaaaaaac tagggctaga agtgattgaa tttgaagcaa gcacaagctc
    29701 tgtccaaaaa ggggaaacac tatacgatac agtactgacg atgtcagcat taggcgtaga
    29761 cgtagcggtt atccgtcatg gtgatgagaa ctattatgac gaactgatac aaagtaaaac
    29821 aatccagtgt tcgattatca atggaggaga cggaagcgga cagcatccaa cccaatgctt
    29881 gcttgatttg atgaccattt atgaagaatt tggtcatttt gaaggtctga aagttgccat
    29941 cgtaggtgat atcactcact ctcgcgtagc taaatccaat atgcagatgt taaaacgtct
    30001 aggcgcacaa gtattcttct caggtcctag agaatggtac gacgatgaat tcgaagtgta
    30061 cggacattat atgccattgg atgaactact agatcaagtt gatgtcatga tgatgcttcg
    30121 ggtgcaacac gaacgccatg atggaaaaga aagtttctca aaagaaggct accatcagga
    30181 acatgggtta acagttgagc gtgcgaagaa gttgcaaaaa catgcaatca ttatgcaccc
    30241 agcaccagtt aaccgtgatg tagaattagc tgattcatta gtggaaggat tacagtcgcg
    30301 gatcgttcag caaatgagca atggagtatt cgtcagaatg gcaatcttag aagcagtgct
    30361 aaatggaaaa gcgtaattat aggaggatga aaaaatgaaa acactcatta aaaacggtca
    30421 gatcaataca cgaaaaaata tgacgacacc agcagaaatt tggatagaag atgggcgaat
    30481 caaagcaatc ggtacaggat tctcagaagc cgaatttgat gaagtgtttg atgcaaaggg
    30541 acaattgatc acacctggtt tagtggacgt ccatgttcat ttgagagagc caggatttac
    30601 atacaaggag acgatcgaag ctgggactcg ctcagctgct cgtggcggtt tcactactgt
    30661 atgcgcgatg ccgaatttaa atcctgtacc tgatacggca gaaaagctga gacaagtata
    30721 tgacatcatt agaaaagatg cagttgtgaa ggtattgcag tatgcgccaa tcacagaaaa
    30781 tctgcgaagt gagaaattag ttgatcaaga agcactgatt gaagaaggtg cttttgcttt
    30841 cacaaatgac ggtgtaggtg tccaaacagc tgggacgatg tatctggcta tgaaagaagc
    30901 tgcaaaaaac aataaagccc tagtagccca tacagaagat gaatctttat tatttggcgg
    30961 cgttatgcac gctggcaaga aggcagaaga acttggtctt cccgggatct taagcgtaac
    31021 cgagtcttct caaattgcta gagatctgtt gctagctgaa gcaactggtg ttcattacca
    31081 tgtttgccat gtttctacta aagaaagtgt ccgtgtaatc agagacgcaa aaaaagcagg
    31141 aatccacgta acagcagaag tttcacccca tcatcttatt ttgatcgacg aagatattcc
    31201 cgaagatttc ggcttttgga aaatgaaccc gccgctaaga ggacgggagg acagagaagc
    31261 tttgatcgaa ggcttgcttg acggtacgat cgattgcatc gctacagacc atgcccccca
    31321 tggattagaa gaaaaaagcc aaagtttcat gaaatcacca tttggtatcg taggaagcga
    31381 aacagcgttt caactgatct atactcattt tgtagaaact ggtcgattca cgttggaaca
    31441 agtgatcaat tggttggcag ttaaaccggc tgagattttt ggtttgaatg caggaacgct
    31501 aacggttggt gcccccgctg atgtagcagt ttttgatatt acacaaactt gcacgatcga
    31561 taaagaagac tttttatcaa aaggggagaa tacacctttt atcggctgga aagtaaaagg
    31621 cgaaacacaa atgacttttg tcaacggaaa acttgtgtgg cagaagggag aataaaagta
    31681 tggaacgttt gcttatatta gaagatggaa cagttttcga aggaaaggct tttggtgcag
    31741 atgctagtgt cttcggagaa atcgttttta caacaagtat gactggttat caagaaacta
    31801 tcactgatca aagttttaac ggtcaaatca ttacatttac ctatcctatg gtgggtaatt
    31861 atggggtaaa tagagatgat tatgaatcga tttctccaac atgcaaagga gtagtagtaa
    31921 aagaacatgc acgtgtagct tcaaactggc gaaaccaaat gacgctagat tcatttttga
    31981 aacaaaaagg aattcctgga atatcaggta tcgatacgcg cgcccttact cgcaaaatcc
    32041 gtgaagtcgg aacgatgaaa gctagtatcg ttgatgctgg agattccttc gaacatgcat
    32101 ttgatcagct gaaagcaacc gttctagcaa ccaatcaagt gcagcaagtc tcaactaaca
    32161 aaccttatcc aagtccagga acaggtcgga aagtcattgt cattgacttc ggcttgaaac
    32221 atagtatttt acgagaattg agtaaaagaa actgtaacct cacagtactt ccctataaca
    32281 cagatgccga gacgatttta gcgctatcac cagacggagt catgctgacg aatggacctg
    32341 gtgatccaaa agatgtgcca gaagcaatcg aaatgatcaa aaaaatccaa ggaaaagtac
    32401 cgatttttgg tatttgtctc ggtcaccagt tatttgcttt agccaacggt gcagatacct
    32461 ataaaatgaa attcggacat cgaggattaa atcacccggt acgagaagta gcgaccggaa
    32521 gaattgattt tacttctcaa aatcatggct atgcagtcga tgaagccacg attgatccag
    32581 aaaaactcat cgtaactcat gtagaagtaa atgacggaac agtagaagga gtcaaacaca
    32641 gagattatcc cgctttcagt gtgcagtttc atccagatgc tgcccctggt ccgcatgatg
    32701 cactacattt atttgatgaa tttatggaaa tgatggacgc aggaaaggag cagtaaacag
    32761 atgccgaaac gtacagatat caagaaaatt atggtgattg gatctggtcc gatcatcatt
    32821 ggtcaagccg cagaatttga ctacgcagga acacaagcct gccttgcctt aaaagaagaa
    32881 ggatatgaag tggttttagt aaattctaat cctgcgacga tcatgacgga taaagaagtg
    32941 gcagatcaag tatatatcga accgatcaca cttgaatttg tatcaaggat tcttcgaaaa
    33001 gagcgtccag atgctctcct tccaacttta ggcggacaga caggcctcaa tatggcaatg
    33061 gagctggcag catcaggtat tttagaagaa ttgaacatag aacttctagg aacaaagctt
    33121 tctgcgatcg atcaagcaga agatcgtgat ctattcaaac agttgatgaa agaattgaat
    33181 cagccaatcc ccgagtctga aatcgtcaat acagtagaag aagctgtaga ttttgcaaat
    33241 aaaatcggct atcctgtcat cgttcgtcca gcctttactt taggcggaac tggtggaggt
    33301 atgtgtgaaa atgaagaaga attacgtatc gtatcagaaa atggattaag tctttccccc
    33361 gctacccaat gtttgattga acgaagtatt gcaggtttta aagaaattga atatgaagtg
    33421 atgagagatt cggctgataa tgcaatcgtt gtctgcaata tggaaaattt tgacccggtg
    33481 ggtatccata caggtgattc tatcgtattt gcccctagtc aaacattgtc tgaccatgaa
    33541 tatcaaatgc ttcgtgatgc ttctctttcg attattcgag cacttaagat cgagggaggc
    33601 tgtaatgtcc aactcgctct tgatccacat agttttaatt attatgtgat tgaagtcaat
    33661 ccgcgtgttt ctcgttcatc tgcgttagca agtaaggcga ctggctatcc gatcgctaag
    33721 ctagctgcta aaatagcgct tggattaaca ttagacgaaa tgaaaaatcc tgttacagga
    33781 acgacttttg cagaatttga acctgcatta gattatgttg tagctaaaat tcctcgctgg
    33841 ccgtttgata agtttgaaaa cggagaacgg cttttaggca cgcagatgaa agcaactggt
    33901 gaagtgatgg ctatcggtcg gaatatcgaa gagtctttat tgaaagctgt gcgttcttta
    33961 gaaatcggta cacaccatat cgaacttcct gagttggcag acatcacgga cgatgaccta
    34021 atccaaaaag tggttcgagc acaagatgat cgcctgtttt atgtagctga agctattaga
    34081 agagggtaca ccatagaaga attagcggat ttgacaaaaa tcgatttatt ctttttagat
    34141 aaactgttgc atatcgtaga aatcgaacag cagttgaaac agcagccgtt ggatgacaag
    34201 atattgaaaa cagcgaaaca aaacggtttt acagacaaaa aagtggcgga gctgtgggaa
    34261 ataaacgaag aagccgttcg ccagatgaga aaagaaaatg atttgattcc tgtatataag
    34321 atggttgaca cttgtgcagc ggaattcgaa tcaaaaacac cttattttta tagttcctat
    34381 gaatatgaaa atgaaagttc acgatcagaa aagccctcaa ttctagtact gggatctggt
    34441 cctatccgta tcggacaagg ggttgaattt gactatgcga ctgtgcattc tgtcaaagca
    34501 atccagcagg caggatacga agcaatcatc atgaacagca atcctgaaac agtttcgact
    34561 gacttttcta tttcggataa attatatttt gagccattga ccttcgaaga tgtgatgaat
    34621 gtgatcgagc tagaacagcc gataggagta atcgttcaat ttggtggtca gacagcaatc
    34681 aacttagccg aacctttgac tgctgctggt gtaaaaatct tagggacaac gatcgaagac
    34741 ttggatcgtg cggaaaatcg tgatttattc gagcaagcgc tgaaagagtt ggatattcct
    34801 caacctttag gggatactgc tacaagtaaa gaagaagccg tggttatcgc ttcgagaatt
    34861 ggttatccag ttcttgttcg tccaagctat gtattaggcg gacgtgcgat ggaaatcgtt
    34921 gaaaaccagc gagatttaga agattacatg gaacatgctg tgaaagcatc tccagaacat
    34981 ccagtactag tggaccgtta cttgcttggt ggtgaatgcg aagtggatgc gatttgtgac
    35041 ggtgaaacag tactcatccc agggatcatg gagcatattg agcgtgctgg tgtccattca
    35101 ggggattcaa tggctgtgta tccacctcaa acattatctg aatcgatcaa gaaaacgatc
    35161 gaagattaca cgatccgctt agcattaggt ttgaattgtg tcgggatgat gaatatccag
    35221 tttgtcatcc atgaaaatga ggtttatgtg atcgaagtca atcctcgagc aagtcggact
    35281 gttccattct taagtaaggt gacaggaatt ccaatggcac aaattgcgac gaaagctatt
    35341 ttgggagaga aactaaagac acttggttat gaaaacggac tttatccaga aacaaaagaa
    35401 gttcatgtta aagcacctgt cttttctttt acgaaattgc agaaagttga tacttactta
    35461 gggcctgaaa tgaaatcgac tggagaagta atgggatctg acagacaatt agacaaagct
    35521 ttgtacaagg cattcgaagc ttctggatta cacttgcctg aatatggagc cgtattattt
    35581 acgattgcgg acgaaacaaa agaagaagca ctagaattag ctaaacgttt tacagaaatt
    35641 ggctatagtc tgataggaac gaaacataca gctgcttatt tcgaaaaaaa tggtctggtc
    35701 gttgaaacag tagcgaaaat ttctgaggaa gcagcagaaa aaaatgtagt cgacttaata
    35761 agagatggta aaacacaagt ggttgtcaat acgattgata aagatcgggg aaatgcttct
    35821 aaagacggtt tcatcatccg aagagaagca gttgaacatg gtattccatt gtttacttct
    35881 ttagacacag cagatgcgat cgttcgagtg atggaatccc gtgctttttc aactaaccct
    35941 atttaacggc gagcacatgt taagacaaaa agacgaaaaa ccgttgcagg aggggacaga
    36001 tgaaacaaga aatgatggaa atcgttcagc aaaaacagct ggcaccaaag atttttgaaa
    36061 tgacattgaa aggtgatcta gtaaaagaaa tgcagcaacc aggacagttc ttgcatattc
    36121 tcgtgccgcg tgcagacttg ctattacgcc gaccgattag cttgaatcat atcgaccacg
    36181 aaacaaatac ttgccgtatc atttatcggg tggaaggtga ggggactaga gtcttctcta
    36241 ctctttctgc cggagaccat ttagatgtca tgggtccttt aggcaatggt tttgatttgt
    36301 ccaatcttca tacaggagac gaagtattta taatcggtgg aggaatcggt gtccctcctc
    36361 tatatgagtt atcaaaacag ttagtcgaaa aaggaattaa gccaacgcat tttttaggtt
    36421 ttgccacaca tgaagtcgtt tattatgaaa aagaatttaa tcgtctagga gaaacaagaa
    36481 tcgctactga cgatggaaca tacggtatgc acggaaatgt cggtaattta ttgttaggaa
    36541 cgaagacgga acctacagct gtttttgcat gtggttcaaa cgggttattg aagacagtgg
    36601 aacagctgtt ttcttcgcat caaaatgtcc agttatcatt agaatcccgc atggcatgtg
    36661 ggataggggc ttgctatgct tgcgtttgtc atacgccgga agatgaaaca ggaacaaaaa
    36721 gtgtgaaagt ttgtgacgaa ggaccgattt ttaaaatagg agaggtaatt atatgaatga
    36781 gaatccttta gcggtcaaac ttcctggcct agaattaaaa aatcctatca tgccggcaag
    36841 cggctgtttc ggttttggca aagaatacgg aaaatactat gatttgaatc agcttggatc
    36901 gatcatggtc aaggcaacga ctccaaatgc ccgctttggc aatcccacgc caagagtggc
    36961 ggaaacacca tctggcatgt tgaatgcaat tggtttgcaa aatcctggtc tagacgttgt
    37021 tatgcataaa cttcttccag aattagagga gtacaatgag ttacccatca tcgcaaatgt
    37081 tgctggtgct tgtgaagaag actatgtaga agtttgtagc aaaattggcg aagcaccaaa
    37141 tgtgaaagca atcgagctga acatttcttg cccaaatgtc aaacatggcg gaattgcttt
    37201 tggaacagat tctgatgttg cttttcaatt aacacaagca gtaaagaaag tttcttctgt
    37261 tcctgtctat gtcaaattgt ccccaaatgt aacagacatc gttccaatcg ctcaggcaat
    37321 cgaagctgga ggggcagatg ggtttacgat gatcaatact cttcttggta tgcggattga
    37381 ccttaagaca agaaaaccga ttttagccaa tcaaacaggt ggactctccg gaccagcaat
    37441 caagcctgtc gctattcgtt tgattcacca agtagcaagt atatccagcc ttccaatcat
    37501 tgggatgggc ggcgtgcaga cagtggatga tgttcttgag atgtttatgg ctggagcaag
    37561 tgctgtagct atagggaccg cgaatttcac cgatccgtat atctgtccta aactaattaa
    37621 agagctccct gtgcgaatga gcgaactagg catcgaatcg ctggaaagat taatcaaaga
    37681 agtgagagag gaacgtgaac gatgaatcaa ctagaccaac gaccaattat tgcattagat
    37741 ttttcaacta ggcaagaggt agaagacttt cttcgatttt tcccgaaaga agaaaaattg
    37801 tttgtgaaaa tcggaatgga attgttctac caagaaggac ctgaaatcgt acgttatcta
    37861 aaagaggctg gtcataatgt atttttagat ctgaaacttc acgatattcc gaatacggtc
    37921 gaaaaagcaa tgcggggatt ggcaaagctt ggtgttgatc tcacctgtgt tcatgccgct
    37981 ggcggtattc gtatgatgga ggcggcaatg cgaggattag aagaggggac tccagaaggt
    38041 ggaaaacgtc cgctacttct agctatcact cagcttactt ctacaagtga agaagaaatg
    38101 catgccgatc aactaatcga agtttcttta gaaaaaagtg tgatccatta tgctagctgt
    38161 gccaaaaaag caggattaga tggtgtggtt tcttctgctt gggaagtaga agcgatcaaa
    38221 gaaatggcag gagacgaatt tgtttgctta actccgggta taagaccaga aggaacagtc
    38281 gcaggagatc agacaagagt agtcacacct tctcaggcaa aaaagatcgg ctcaactttt
    38341 atcgttatag gtcgaccaat cactcagtca actaatcctt ataaagcata tcaaacgatt
    38401 caaacagaat ggagctaacc taaaatgaat gttgaacaaa gtatcgcaaa agacttatta
    38461 gaaattgaag cagtattttt aaatccaagt aatcctttta catgggcaag tggaatcaaa
    38521 agcccaattt actgtgataa ccgaatcacg atgagctatc caaaagtccg aaaagagatc
    38581 gcaaaaggat tagcaagcaa aatcaaagaa gcttaccctg aagtacaagt gattgctgga
    38641 actgcaacag caggaatccc tcatgccgca tgggtagcgg aaatactgga tttgccaatg
    38701 gtctatattc gaagtaaggc gaaagatcat gggaaaggta accaaatcga aggacgtata
    38761 tttgaaggtc agaagatggt tgtgatcgag gatttgattt ctacaggcgg aagtgtcttg
    38821 gaagcagctg aagcagcaaa aagagaaggt gcggatatcc ttggtgttgc ggctatcttt
    38881 acgtatgagt tgccaaaagg aaaagcaaat ttcgaaaaag ccgaaatccc tcttatgacg
    38941 ttgaccaatt attctgtatt gattgaagca gctttagaag atcgttatat cgatgagcaa
    39001 gaattaactc tgctaaaaga atggaaaaaa gatcctgaaa attggcagat ttaagcgcgc
    39061 ttgatgaaga tagagaaatc cgatttgtgt ctccagaatc atcaattgga atagcaaaaa
    39121 tccaaaaact gattgcgaga agcatctttt catcaggtat gaaaagaaac ttctatcgtg
    39181 atcagttttt gattttttta aaattcattt ttctaagact ggttagcaga aagaagagaa
    39241 taatctcttc tcttttttct attatatata gattttctct attttttggt aagggagctg
    39301 tttcaaaaat ggtaaagagc ggaaatgttg cgaatatcag ttatttaatg atatgatatt
    39361 cggaaaaaga aatctcaaag ggaggtaact tttatggggt tgaatgaatt tattttagga
    39421 ttgaacaatt tagagacgat cacaagggca cctggatttt ttaaatatac agagcataca
    39481 gttgcagcac attcgtatcg tgtagcatct attgcgcaag ttctaggaga cattgaagaa
    39541 gcgaatggac aaccgatcga ttggaaactg ctctatgaaa aatcattgaa tcatgactac
    39601 acagagcgtt ttattggtga tatcaaaacg ccggtgaaat acgcaagcaa agagttaaga
    39661 gggatgctgc aaacagttga agaaaagatg acggacgaat tcatcaacca agagattcca
    39721 gctgagttcc aagaagttta tcgccgtcgg ttgttcgaag gaaaagatga aaccgtagaa
    39781 ggagaactat tagccatttc agataaggtt gaccttcttt atgaatcttt tgatgaaatc
    39841 atcaaaaata acccggaaaa agtttataag gagatgttca ttgaggcagt gactacgatt
    39901 aaaagctttg aacatcggcc ttctgttcag tatttcttta aagagatatt tccggaacta
    39961 ttgaaccagg aattttatgg aaaagaggcg tttttagaaa ccgtctcaac gattgtaaag
    40021 aaagaagaaa aataaaaatg atatgagatg cagggggaag tatagttgaa aaagaatatg
    40081 gatgtcgaat ggggctattc tggagacaaa ggtccggaaa attgggcgag tttatgtgat
    40141 tggtttgcga gaggtgcgga atttccattg cagtcgccta ttcatttgac caagggggaa
    40201 gaaaccaaaa tagaaggaga cacgctttcc tttcattatc aaaagcaacg gtttactgac
    40261 aaggaattca aaaacacgat tcatttagta ccttttgacc aactcagtta tgtagagttc
    40321 aagaaagaac gctattattt gacagatatt catttccact tgccttctga acatatcatc
    40381 aacggaaaac aggaagatat tgaatttcat tttgttcata tgaacagcaa aaaagagaat
    40441 ctagttgtgg gtgtcatgta ccagctaatg gtacaggaag gttggctgta taatcaagaa
    40501 aatggggaaa gttggaactt agaaaaacat gagcattggg taaatccgga tgtgttcttt
    40561 ccggagcaaa aaagccattt ccattatatt ggctcattga caactccgcc taccagcggg
    40621 ccaatccaat ggtttgtaat ggatcatgta ggaaaactga accaagagtt tcttctcccc
    40681 ttcgatggtc agtatgctcg accgaacaac cgaccaatcc agcccttgaa tggaagagaa
    40741 atttattatt tcgaggagtt tgagcaatga atattcagca gatgaaatac gtggtcgctg
    40801 tagcaaacaa tggtagtttc agagaagcgg caaagaaaat gtttgtctcc cagccaagtc
    40861 tttcagctgg tatcaaagaa ttagaaaccg agttagggat cacgctgttt actcgaacga
    40921 atcgaggggc atatttaaca gaagaagggc aagacttctt aaatcgtgcc gagaaaatat
    40981 tggtccagct tgatacatta gaaactcact atctaacgag tgaaaagaga gacaattttt
    41041 cgatcgctgc ccagcattat gatttcttag gtcctttgac cgcacagcta ctcgaggaat
    41101 tcaaagacga gatcaaacaa tttcggatca tggagacgac aacagcgaga gtgatcgaag
    41161 aagtcaaaga gcagcacagt gagatcggca ttatttatat gaatgagcat aatcaagctg
    41221 gtatcagaag atatttacaa caaggagagc taagtggccg cagcattgga aaattcaaaa
    41281 cgcatatttt tttaaggcaa ggacatccat tagctgaaca cgcagagatc accaaagaag
    41341 aattgttatc ttatcctcaa gttcgtttta cacaggatgg aaataatttc ccgtattttt
    41401 atgaagacct tatcgagatc cctgatcaag aaacagtgat ttatacgagt gatcgaggta
    41461 ctttgatgaa tatcgttctt gaaactgatg cttacgcttc aggatctggt attgtgattg
    41521 gagggattcg cgagcacttg cggttaatcc ctttggcaga aggcgaacta aatgaatttt
    41581 atatcattta ttcggcgaaa cgtccgctca gtgaaatcgc tcaaagattt atcaaagagc
    41641 ttactcggtt actggaccag cagagctaag aaaagcagat gagaacgctg tttattgaac
    41701 accgttgatc aaaaaagagg ggttgtgaca gaattttgtc acaactcctc tttttgtagc
    41761 aaacaattta taactaattg ctgttgtggg aaagtacgca aatatgattc tagaaacact
    41821 cattgattac ctgttttgtt tcatagctgt aattttttct tcttctggtg tcacgataat
    41881 cgtcttttgg ttttcataaa taacataacc aggcttggcg ccatttggtt ttcggatatg
    41941 ctttacctgt acaagatcaa ccggcacttg ggcagagtat cggtattttg aaaaataggc
    42001 agctaactcg gcagcttctg taattgtttc atctgagggc ttgtcacttt taatgatgac
    42061 gtgcgaaccg ggtatatttt ttgcatgaag ccaatagtcg gtttttttag ctgtcttcat
    42121 tgtcagctgg tcattttgaa gattgttttt accaacaaga atgagcgttc cgtcagaaga
    42181 aaagtattga tcaggctgag atggtttctt acgtttttgt ttttttaagt tcttcttttt
    42241 caggtatcct tctgaagtca attcttcttt aattgcttcg atatccattg ggccggcaat
    42301 ttccagttga gataagacag attcaagata ttggatttca tctttggctt cttggatttg
    42361 ttcgccaatc agcttaacag cgttcttcag cttttggtat cgatggaaat atttctgtgc
    42421 attttgattt ggtgtcaatg ccggatctag tgctattttg attggccgat cttcttcata
    42481 ataattaggt aaaacaactt cttttgcgcc gcgtggtact tgtgtcagaa aagtagtaag
    42541 tagttcgcca tttctacggt aattctcagc gttttcggat tctttgagtg tttgttcacg
    42601 ttttttcaat ttatttttat ttcgttttag ttcattttcg atttttcgaa tcagttctcc
    42661 gccttgttgt tttgcccgat ctttctctgc tttttcgtga taatagctat ctaataattg
    42721 actgagtgtt ggataagctg ttacagcaga tgcctgttcg gacaatacct gataagcaat
    42781 cggtgtgaaa aaatctttat tttccgtttc gtaaaaagta ggaataggct gatggctgat
    42841 ggctgagaaa aattcgtccc atacaaccat cttttcatta ggacgttcca gtaatctttt
    42901 ggtcagctct tgagcgatat cgaaaccgat tccctgaaac tgacgttgga ttgcttttgg
    42961 atctagttca gtttgggaaa gccgctgaaa gattttttct ttctcggagc taaatgggtt
    43021 caagacctct tgttttggcg gagcaacata ttctacacca ggaagcaaag aacgataagt
    43081 gttttgagag cttccaatgt gtttgatcgc atccagtatt tttccagttt ctcgattaac
    43141 taagacgatc gtactatgac gtcccattaa ttcaacgatc aatatgatat tttgtagatc
    43201 acccaactcg tttcgtttag caaagtggaa atggatcact cgatcatttt cgatttgttc
    43261 gatgtcttct aaaatagcgc catccaaata ttttcgaagc atcatcacga agttaggcgg
    43321 attatcagga ttctgataat cgatttgggt aatctgtaca cgagcataac ttgggtgcgc
    43381 agataataat aatcgatggt ttttgccgcg tgaacgaatc accagcacga tttcattttc
    43441 ataaggctga tggattttcg agatccggcc agatagtaac gtttcacgca attcgttgac
    43501 catcgcgtgg gtaaatacac catcaaagga catggttcat tcctcatttc ttttcataag
    43561 tatattcatt ataacgaaaa aaagaagaaa aaccaatttg gccgaatagt aaagcaaaag
    43621 tctagaaaaa tcttggacta attacataaa aaacagtgtt tctatcgttg aaatccaaat
    43681 ttttagg
//
LOCUS       DADVXM010000015        42801 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.016, whole genome shotgun sequence.
ACCESSION   DADVXM010000015 DADVXM010000000
VERSION     DADVXM010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 42801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.016"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(135..512)
                     /locus_tag="KB927_000912"
     CDS             complement(135..512)
                     /locus_tag="KB927_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839846.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            768..1496
                     /locus_tag="KB927_000913"
     CDS             768..1496
                     /locus_tag="KB927_000913"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBB6839847.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1496..1750
                     /gene="purS"
                     /locus_tag="KB927_000914"
     CDS             1496..1750
                     /gene="purS"
                     /locus_tag="KB927_000914"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBB6839848.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1752..2423
                     /gene="purQ"
                     /locus_tag="KB927_000915"
     CDS             1752..2423
                     /gene="purQ"
                     /locus_tag="KB927_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBB6839849.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2424..4646
                     /gene="purL"
                     /locus_tag="KB927_000916"
     CDS             2424..4646
                     /gene="purL"
                     /locus_tag="KB927_000916"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBB6839850.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4631..6070
                     /locus_tag="KB927_000917"
     CDS             4631..6070
                     /locus_tag="KB927_000917"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBB6839851.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6093..7145
                     /locus_tag="KB927_000918"
     CDS             6093..7145
                     /locus_tag="KB927_000918"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBB6839852.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7142..7720
                     /gene="purN"
                     /locus_tag="KB927_000919"
     CDS             7142..7720
                     /gene="purN"
                     /locus_tag="KB927_000919"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBB6839853.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7717..9252
                     /gene="purH"
                     /locus_tag="KB927_000920"
     CDS             7717..9252
                     /gene="purH"
                     /locus_tag="KB927_000920"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBB6839854.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9268..10542
                     /gene="purD"
                     /locus_tag="KB927_000921"
     CDS             9268..10542
                     /gene="purD"
                     /locus_tag="KB927_000921"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBB6839855.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10664..11578
                     /locus_tag="KB927_000922"
     CDS             10664..11578
                     /locus_tag="KB927_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6839856.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11711..13276)
                     /locus_tag="KB927_000923"
     CDS             complement(11711..13276)
                     /locus_tag="KB927_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6839857.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13269..14720)
                     /locus_tag="KB927_000924"
     CDS             complement(13269..14720)
                     /locus_tag="KB927_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6839858.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14734..15750)
                     /locus_tag="KB927_000925"
     CDS             complement(14734..15750)
                     /locus_tag="KB927_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6839859.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15970..17058
                     /locus_tag="KB927_000926"
     CDS             15970..17058
                     /locus_tag="KB927_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBB6839860.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17112..18638
                     /locus_tag="KB927_000927"
     CDS             17112..18638
                     /locus_tag="KB927_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBB6839861.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18640..19845
                     /locus_tag="KB927_000928"
     CDS             18640..19845
                     /locus_tag="KB927_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6839862.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20102..21079
                     /gene="guaC"
                     /locus_tag="KB927_000929"
     CDS             20102..21079
                     /gene="guaC"
                     /locus_tag="KB927_000929"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBB6839863.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21343..22767
                     /locus_tag="KB927_000930"
     CDS             21343..22767
                     /locus_tag="KB927_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBB6839864.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23228..24337
                     /gene="pdhA"
                     /locus_tag="KB927_000931"
     CDS             23228..24337
                     /gene="pdhA"
                     /locus_tag="KB927_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBB6839865.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24340..25317
                     /locus_tag="KB927_000932"
     CDS             24340..25317
                     /locus_tag="KB927_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBB6839866.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25342..26985
                     /locus_tag="KB927_000933"
     CDS             25342..26985
                     /locus_tag="KB927_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBB6839867.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26993..28399
                     /gene="lpdA"
                     /locus_tag="KB927_000934"
     CDS             26993..28399
                     /gene="lpdA"
                     /locus_tag="KB927_000934"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBB6839868.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28561..28836
                     /locus_tag="KB927_000935"
     CDS             28561..28836
                     /locus_tag="KB927_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBB6839869.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28842..29609
                     /locus_tag="KB927_000936"
     CDS             28842..29609
                     /locus_tag="KB927_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBB6839870.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29777..31606
                     /gene="typA"
                     /locus_tag="KB927_000937"
     CDS             29777..31606
                     /gene="typA"
                     /locus_tag="KB927_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBB6839871.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31867..33639
                     /gene="recQ"
                     /locus_tag="KB927_000938"
     CDS             31867..33639
                     /gene="recQ"
                     /locus_tag="KB927_000938"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBB6839872.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33753..34055
                     /locus_tag="KB927_000939"
     CDS             33753..34055
                     /locus_tag="KB927_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBB6839873.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34058..35221
                     /locus_tag="KB927_000940"
     CDS             34058..35221
                     /locus_tag="KB927_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6839874.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35247..38675
                     /locus_tag="KB927_000941"
     CDS             35247..38675
                     /locus_tag="KB927_000941"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBB6839875.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38696..39820
                     /locus_tag="KB927_000942"
     CDS             38696..39820
                     /locus_tag="KB927_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839876.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39810..40247
                     /locus_tag="KB927_000943"
     CDS             39810..40247
                     /locus_tag="KB927_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6839877.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40231..40569
                     /locus_tag="KB927_000944"
     CDS             40231..40569
                     /locus_tag="KB927_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBB6839878.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40688..41248
                     /gene="rsmD"
                     /locus_tag="KB927_000945"
     CDS             40688..41248
                     /gene="rsmD"
                     /locus_tag="KB927_000945"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBB6839879.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41245..41736
                     /gene="coaD"
                     /locus_tag="KB927_000946"
     CDS             41245..41736
                     /gene="coaD"
                     /locus_tag="KB927_000946"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBB6839880.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41726..42769
                     /locus_tag="KB927_000947"
     CDS             41726..42769
                     /locus_tag="KB927_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBB6839881.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
BASE COUNT        14124 a         7336 c         9560 g        11781 t
ORIGIN      
        1 aaccaaaaaa gaagcagatc cgttagcggt tctgcttctt ttagtttatt atattttctt
       61 atcaataata ggaacctgat tttaaaagcg gctacctctt taccgtgcct ctttacatac
      121 aaaaaataga ggaattaagc gtaaatggct tggctattat aactaaaatg ctggttatgg
      181 agatgttgca gcaagttttc gagaaaagcg tattccatct cttgtccatt gaataagatc
      241 tggatacgat aatgattttt gaaacgcttc tgttcatgaa tctgactgat tgaaagttcg
      301 cctttgtgtt ctgtctgata aagaaaagtc cttttacggc attcagcaca gcgcttggtt
      361 gctcggcgga tttttcggaa tgtataaaaa ctagtatctt tattgcataa ataaacgtct
      421 ttgatcgaca gcaaatcatt atatagacag gaacgttctt cagctgttaa ttctgataaa
      481 aaaagctgac cttgttttat tgcatcttcc atcggcaagt gcctcctcga acccattatc
      541 caaattttta gttaattcta atataccatc attaagtata aatgtaaacg cttgttgatg
      601 gtataagatt ttcgtttctg ataaaacacg aacattaaaa gaatctaatg ccttaaatgt
      661 acatattttt gttgatttat aaaaagatga ttgctaaaat ttaaagtgaa aaaacgaaca
      721 aaaaacgatg tatttgcttt taatgtaaat aaaaaggaga gacgtacatg gagaagaaag
      781 aacttttgta tgaaggaaaa gccaaaaaaa tatatcttac ttctgatgag aacttgattt
      841 ggatagaata tttagatcaa gcaactgcgt tgaatggcgc gaggaaagac cagataagtg
      901 gaaaaggaga attgaataat caaatcacaa gtgcaatttt ccgttatctg actcaaagag
      961 gaataaaaaa tcattttatt gaacaattgt ctaaaaccga acaattagca aaaaaagtac
     1021 aaattatccc tctggaagtg gttatccgaa atattgcagc aggaagtttc tcaaaacgtc
     1081 taggtgttcc cgaaggtaaa gaattcatca aaccaatcat tgaattctac tataaggatg
     1141 accagttgga tgatccattt atcaatgaag agcatatcta tttcttacaa cttgcaaagc
     1201 cggaagaaat cagtgagctg aaagcccaag cgttggctat taatgaaatt ttgaccgaat
     1261 tatttgctaa ggtcggtttg gttttagtag atttcaagct agaatttggc cggtcgaatg
     1321 gacaaatttt gcttgcggat gaagtaacac cggatacttg ccgattatgg gatgaacgta
     1381 cgaatgaaca tatggacaaa gacgtttacc gcagagatct aggtgatttg atcccagtct
     1441 atcaagaagt atataaccgt ctatcggaac taactgaaga aaaggagcga gtatgatgta
     1501 tttcgtaaaa gtatatgtaa cctataaaga ttcagtgtta gatcctcaag gggaggcagt
     1561 aaaaaaagca gtccatcgta tgggatatga aacaatcgaa gatatccgaa taggaaaata
     1621 ctttgagata caacttgctg atgcagaaga accaatcgat acagtgattg aaacgatttg
     1681 tgacaagctg cttgcaaatg taaatatgga aacataccga tatgaaatca aaaaaatgga
     1741 ggaagtataa catgaaattt gcggtcatcg tttttccagg ttcaaattgt gacgcagata
     1801 tgttatgggc agttcgcgag atcatgggcg ctgatgccga atttgtacgg catgatgagt
     1861 cctctttaga aggatttgat ggggttttac tgccgggagg attctcctat ggtgactatt
     1921 tgagatgcgg tgcgattgct cggttttcta caatcatgga agaagtgatt cgttttgctg
     1981 aagaagggaa accagtattc ggtacatgca atggattcca gatattgaca gaagcaggac
     2041 ttttgccagg tgtactgaga cgaaatgagt ctttgcattt tatttgcaaa actgtaccat
     2101 tgaaagtcaa ccccaagacg gcctttactt cagagtatga agccgacgaa ataatctatc
     2161 ttccagttgc tcatggggaa ggaaattatt tctgtgacga agaaacactt caagaactaa
     2221 aaaaaaataa tcagattgcc tttacttata atgacaacat caacggcagc gtggaaaaca
     2281 ttgcagggat tacgaacaaa gcagggaatg tgttaggaat gatgcctcat ccagaacgtg
     2341 cagtagaaga cttgctagga tcagaagatg ggaaacggtt ctttgcttcc attttaaaaa
     2401 acttcggaaa ggtgaccgta tagatgaaaa cattgaaaga accgacagct gaagagatca
     2461 agaaaaaaag aatctatgcc gaatggggat tgactgatga agaatatcga atgatcgaag
     2521 aagatatctt aggaagaatg cctaattata cggaaactgg actgttttct gttatgtgga
     2581 gcgaacattg ttcctataaa aattctaaac cggttctacg caaatttcct actagtggac
     2641 ctcatgtgtt gcaaggccct ggagaaggcg caggcatcgt cgacatcggt gatggactag
     2701 cagttgtctt caaagcagaa agtcacaatc atccttcagc cgtggagcct tatgaaggag
     2761 ctgcgacagg agttggcgga atcatcagag atattttcag catgggggct cgtccaattg
     2821 cgttgctaga ttcattgagg ttcggcgaat tagataatcc aagaacgaaa tatttactag
     2881 aagaagtagt tgcaggtatc ggcggatacg gcaattgtat cggcataccg actgtaggcg
     2941 gcgaaattgc atttgatcct tgttatgaag gaaacccatt agtcaatgca atgtgcgtag
     3001 gtttgattga acacaaacat atccagaaag ggcaagccgc tggcgtcggt aattcgatca
     3061 tgtatgtagg tgcaaaaaca ggtcgcgacg gtatccacgg agcaactttt gcctcagaag
     3121 aatttaatca agaagaagaa cagcaacgtt ctgctgtaca agtaggcgat ccttttatgg
     3181 aaaagctgct gcttgaagcg tgtttggaat taatcttgca tcattcggat tctctaatag
     3241 gtatacagga tatgggagca gcaggacttg tttcatctag tgcggaaatg gcttcaaaag
     3301 ctggctcagg acttatattg acattagatg aagtcccaca aagagaaact gggatgacac
     3361 cttatgaaat gatgttatcg gaatcacaag aacggatgtt gatttgtgtt aaatcaggag
     3421 aggaagaaaa aatccaagaa ctatttcaga agtatgatct agatgcagtc actatcggta
     3481 aagtaacaga cgacgggcaa tatcggctat atcatcaagg agaagaagta gcaaatctgc
     3541 cagtcgatgc attagctgaa gatgcaccag tttatcataa agaaatgaaa gaaccagctc
     3601 gaatcgtaga atttcagcag ttagctcctt atcagccagt tatcgaagaa cctggacaag
     3661 tattgcttga tctgctgcag caaccgacga ttgcttcaaa acgttcaatc tacgaaactt
     3721 atgattcaca agtacaaacc aatacagttg tccgtccagg aagcgatgct gctgtgatga
     3781 gggttagagg gacgaataaa gcgttagcta tgaccacaga ctgcaacgcg cgctatctgt
     3841 atttggatcc aaaaatcgga ggacaaatag cagtggcaga agctgctaga aatattattg
     3901 ctagcggtgg taagcccttg gcgatcaccg actgcctgaa ctatggttct cctgataaac
     3961 cagaagtttt ttgggaatta tcgacttcag ctgacggaat tgctgctgcg tgtgaaacgt
     4021 taggaactcc tgttatttca ggaaatgtct ctttatataa tgaaacggat ggtcaagcaa
     4081 tctatccaac accaatgatt ggtatggtcg gattgattga ggatcataaa catatcacta
     4141 ctcaggaatt caaaaaatca ggggatctaa tctatatatt aggtaagacg tttgcagatt
     4201 ttgatggcag tgaattacaa aagatgcagc ttggaagaat cgaaggtgtg atccgaaact
     4261 ttgatctatc cattgaaaag agaaaccaag agttagtatt gacagccatc caaaacggat
     4321 tgattgaaag tgctcatgac tgttcagaag gtggcttggc aattgcactg gcagaatcag
     4381 ctttcaaaca tcagctaggg atatctgtac agtttgaatt gtcctctgct caattatttg
     4441 cagaaactca atcaagattt gtgttgacag tcgcaccgga aaataagaca cgattcgaag
     4501 aaatgatggg agatgctgct gttttagcag gtaaggtgac ggatgaagcg ataatcgaaa
     4561 tttcagcaac tgacggtcag atcaaaatag aaactgcagt agcaagaaag tgctgggagg
     4621 atgcaatcgt atgtcttatg aagtgaagag tttaaatgaa gaatgcggga tcttcggtgt
     4681 ttggggtcat ccagacgccg ctagtgtggc atacttcggg ctccatagtc ttcagcatcg
     4741 aggacaagaa ggtgcaggta tcgtgtccaa tgatcgagga aagcttaagg ggcatcgaga
     4801 tttggggctg ctttctgagg tattcaaaga tcaaagaaaa ttgcagcagt taacaggaga
     4861 agctgcaatc ggacatgtac gttatgcaac agcaggcaat ggaagtgtgg acaatattca
     4921 gccttttcta ttcaaatttc atgatcagtc gatcggctta gcgcataatg gtaacttgat
     4981 caatgctcgt tcccttagaa aagagttaga ggaaaatggg gcgatcttcc attctaactc
     5041 cgatacggag atattgatgc atttgatccg acgaagtgaa gaaacagatt ttttaaataa
     5101 attaaaaagt gctttgaatg aagtcaaagg tggctttgcc tatttattaa tgacagaaac
     5161 ggcaatgatt gccgctttgg acccaaatgg ttttcgtcca ttagcaatcg gacaaatgaa
     5221 aaacggagca tacgtgattg cctcggaaac ttgtgcatta gaagttattg gggcacgttt
     5281 tataagagat gtccagcctg gtgagatagt gatcatcaat gacgaaggaa tccagattga
     5341 ttgctttacg aaggacacgc agctttctat ttgttcgatg gaatatatct attttgccag
     5401 accagattca aacatcgcag ggatcaatgt gcatactgca cggaaaaata tgggacggaa
     5461 tttagcgaaa gaatcgccag taaaagcaga tatggtcgtt ggcgtaccta attcttcttt
     5521 gtcagccgca agcggttatg cggaagctag tggaatccct tatgaaatcg gattagtaaa
     5581 aaatcaatac attgcccgaa catttatcca gccaacgcct gagctaagag agcaaggtgt
     5641 tcgaatgaaa ttatctgctg tacgaggagt agtggaaggt aaaaaggtga ttatggtcga
     5701 tgattcaatt gttcggggta cgacaagcag acggatcgtc catcttttga aagaagcagg
     5761 ggcaaaagaa gtccatgtga ggattgcttc tcctcctttg aaatatccat gtttttacgg
     5821 gattgatatt caaacgcgta aagaactcat tgcggcaaat cacacgattg atgaaatcaa
     5881 agaatgtatc ggtgcagatt ctttaggttt tttaagtgaa gagggtctga tcgaatcgat
     5941 cggtctggaa aaagatgctc cgtattcagg attgtgtatg gcttatttca acggagatta
     6001 tccgacgccg ttatatgact atgaagaaaa atatcaggaa tcactaaaag aaaaagtatc
     6061 gttcttttaa aagcagacca agaagggagt atatgaattc aatggcaaat gcatacgcaa
     6121 aagctggcgt agatgtcgaa gctggatatg aagtagtaga acggatcaag aagcatgtca
     6181 aaaaaacgga acgtttaggt atgatgggcg ctataggagg attcggcggt tgttttgatt
     6241 tatcggtctt tcaattaaaa gagccagtcc ttgtctcggg gaccgatggc gtggggacga
     6301 aattagcagt ggcaatcgaa gcagacaaac acgatacaat cgggatcgac tgcgtagcga
     6361 tgtgtgtcaa tgatatctta gcacaaggcg cagagccgtt atatttctta gactacttag
     6421 caacggggaa aaatgatccg ttacgtttgg aaaatgtagt aaaaggtgta gcagatggat
     6481 gtgttcaagg aaatatggcg ctgattggcg gagaaacagc tgaaatgcct ggtatgtact
     6541 caggtaatga ttatgatcta gccggatttg ctgtagggat agctgaaaaa tctcaattat
     6601 tgacaggaga aacgatcaac ccaggagatg tgttgcttgg aatagcatct agcgggattc
     6661 attcaaatgg gtactctctt gttcgcaaaa ttttctttga gcagcagcag ttttctttat
     6721 catcaaaact gccagaattg aaaaaaacac ttggcgaaga attgcttgag ccaacgaaaa
     6781 tctatgtttc ttccttgctt ccgctgatca aagaaaagaa aataaaagga gctgcacata
     6841 tcactggtgg agggtttgta gaaaatatcc cgcgaatgtt accagaatct atggctgcac
     6901 aaatcaaact tggctcatgg ccgattcttc caatattcgg ctgtttacaa aaatatggtg
     6961 aaattcctga gatggagatg tatgaaatct tcaatatggg catcggtatg gtcctggcag
     7021 tcgaagaatc gaaagtaaaa gaaatagtac acgaaattga gcaagctggc gaaaaagttt
     7081 atgaaatcgg gaaagtgatc gccaaagaaa aacatcgtgt ggtgtttata ggagaagaac
     7141 gatgagaatc gctgtttttg cttctggaaa cggaagcaac tttcaagcgc tagccgatta
     7201 tctatcgaaa aaaggattgg aatcttcgat tgactggttg ttttgtgatc agcctgaagc
     7261 atatgttttg aaacgtgcaa ctgcgttgag tgtaccggca gattgttttt cacctaaaga
     7321 atttgattca aaaaaagagt atgaagaagc aattttgcat aaattgaaag aaaaaaagat
     7381 cgatttgatc gtattagctg gatatatgcg aatcattgga ccggtattgc tgaaaaatta
     7441 tgataaaaga atcatcaata tccatccgtc tcttttacct gccttccctg gtttgcatgg
     7501 catacgtgat gcctttgaag ctggagtaaa agaaacgggt gtcacaattc attatatcga
     7561 ccaaggtgta gatactggac caatcatccg gcaggaaaaa gtgagaattg aacaggagga
     7621 cacgttcgat tctttagaag aaaaaatcca tagagtagag catcgaatct atccagaagt
     7681 gattagtgaa attattgaaa atggaggcta tctgaaatga caagagcatt gatcagtgta
     7741 tcagataaaa ctgggattgt agcattcgcc caaggtttga ttgaacaagg agtagaaatc
     7801 atttcaacag gaggaacaaa gcatgcgttg gataaagctg ggatcaaaac gctttcgatc
     7861 gaagaagtga cagggtttcc tgaaatgatg gatggccgtg tcaaaacact tcatcctaaa
     7921 atccatggtg gtcttttagg aagacgcgat ctccctagcc atatggaggc aatggaaacg
     7981 gaaaatatcc aaccaatcga ctttgtttgt gtcaatttat atcctttcaa agaaacgatt
     8041 atgaaaccag atgtcgaaat agcagaagct attgaaaaca ttgatatcgg tggtcctagt
     8101 atgctccgta gtgcagcaaa aaaccatgaa tttgtcacct ctgttgttga tccatctgac
     8161 tatgaagaag tactttcaga attacgtcag tatgggcata cttcactttc tttcagacaa
     8221 aaactagcgg caaaagtctt tcgtcatact gcggcatatg atgcactgat cgctcaatac
     8281 ttaacggatt gggtggaaga aaaagaaccg gaaaaattga cacttacgta tgaacgaaaa
     8341 caaacgcttc gttacggtga aaatagccat caagccgctg ccttttatca gtccgctctt
     8401 ctggaaaaat attcgatcgc agcagcaaaa caactccatg ggaaagaact ttcttataat
     8461 aatatccgag atgcagatgc tgcgctacgg atcatgaagg aatatgacga gccaacggta
     8521 gtcgccttga aacacatgaa tccttgtggt attgggacag catctacgat tttagaagcg
     8581 tgggaagcag cgtatgaagc agatcctgtt tcaatctttg gtgggatcat cgttttgaat
     8641 cgagaagtag atctgccaac agcagaacag atgcataagc tgtttctaga aatcatcatt
     8701 gccccttctt atacacaaga agctttggaa ttactgcaaa aaaagaaaaa catccgatta
     8761 ctgacagtag actttgcgca ggaagaaaat caaaatcgag aagaaacggt ctcagtctta
     8821 ggtggacttc ttgtacaaga tcaagatctg gcaatagaaa atgaagaaga gtggaaagtc
     8881 gtgacaaaac gtaagccgac tccagcagaa gcaaaagcat tagcgtttgc ttggagagct
     8941 gtcaaacatg tgaaatctaa tgcgatcgta ctggcaaacg aacgtcagac agtaggaatc
     9001 ggagccgggc agatgaatcg agtcggttca gtaaaaattg cgattgaaca agcgcaagag
     9061 aaaatggaag gtgcagtttt agctagcgat gcttattttc caatggatga ttcggttgaa
     9121 tatgcagcca aacatggtat aaaagcaatc attcagccag gaggaagcat caaagaccaa
     9181 gattctattg atatggcgaa taaatacgat ctagcaatgg tctttactga tgttcggcat
     9241 tttagacatt agagaggagt cggataaatg aacattttgg tgatcggtgc aggtggtcgt
     9301 gaacatgcaa taagtaaaaa acttttagcc agtccgaagg tggatacggt gtattgtgcg
     9361 ccaggaaatc cggggatgac aaaagatggt atcaattgtg tcgctatcag tgagcgagat
     9421 cattcagcgt taatccattt tgttaagaaa gaggctattg attggagtat cgttggtcct
     9481 gaagttcctt tgttaaatgg gatcgtcgat gattttatgg cggaaggatt gaaaatcttc
     9541 ggtccgacaa aagcagcagc tctgatcgaa ggttcgaaaa gttttgctaa acaattaatg
     9601 gatacttatc aaatcccgac agctaaatcc agaagttttg aatgttacga aaaagcagca
     9661 gcgtatatca aagaaaatgg tgcgccaatc gtagtgaaag cggacggctt agcagctggg
     9721 aaaggtgtag tcgtggctac cacagtgaag gaagcgctgg atgcggcaga acaaatgttg
     9781 aaccagcatc gatttgggga tagtagcaaa aaaatcgtcg tagaagagtt tttggcagga
     9841 gaagaattct cccttttggc gtttgtccgt aataccaagg tgtatccgat ggtcatttcg
     9901 caagatcata agcgggcatt tgataacgat aaagggccaa atacaggcgg aatgggtgct
     9961 tattcaccag taccgcaaat ttcaaaaaag atgattgaaa aagctgtgga agaagtttta
    10021 aaaccagcgg ctttgggaat gaaagaacta ggacgctctt tcacgggtgt tttatatgcg
    10081 ggtttgattg ctacgaagga aggaccaaaa gtgatcgaat tcaatgcgcg tttcggtgat
    10141 cctgaaacgc aagtcgttct ttctcggttg aagagtgact ttgcgcaagt aatcgatgat
    10201 ttattagaga atcgtacagt agagttaaag tggcagcaag aaggatacaa tgtaggcgtt
    10261 gtggttgcag ctgccggtta ccccgaagaa tatgagacag gaatggttct accagatttt
    10321 ctggaagaag agctttctgt ttactatgct ggagtttcct caaataacgg caaactagtt
    10381 ggagcaggag gacgtcttta tttagtagaa gcatacggtg agacgatcaa agaagcacag
    10441 aaaaaaattt acaccgcgtt aatggataaa acgacagatg gaacatttta tcgtacagat
    10501 attggagaaa aagctgccaa tagcgaactg atcgtgaagt aaatcagctg cttccattta
    10561 taaaaaatac aacaaacata atcggaagcg ccgattttag tgaagccttt tcataaagag
    10621 tgtggtacac ttttgttgtg tatataaata aggaggagtt cagatgaaaa aaattcaatt
    10681 aggtacttct gatcagaaag cagctgcagt gatcttaggc tgtatgcgta tcaacaatgc
    10741 ggaagatcca gtaaaagtga ttgagacagc ttatgaaaac ggcattgatt tttttgacca
    10801 tgcagatatt tatggaaacg gtgaatgtga agaaatcttt gcagatgctc tagcaaaaac
    10861 atcaatcaaa cgagaagatc tttttattca aacaaaatgt ggaatcgttc caggtgtgat
    10921 gtttgatttt tctaaaaaac atatcattga atctgtagaa aaaagtttga cccgtctgaa
    10981 aatggattat gtggatgctt tacttcttca tcgtccagat acattggtag aaccagagga
    11041 agtagctgaa gcgtttgatg aattggaacg gtcaggaaaa gttcgttatt ttggcgtcag
    11101 caatcaaaaa ccaatgcaaa tcgaattgct gaaaaaatat gttcgtcaac cattagtagc
    11161 taatcagctg caatttggct tgaaacatac tggaatgatc gatcaaggga ttcatgtcaa
    11221 tatgacagat gaagcaagta tcgatcatga cggtagtgta cttgattatt cccgattgca
    11281 tgatatgacg atccaagcat ggtcaccata ccagtatgga ttttttgaag gtgtatttat
    11341 cgggaacgaa aaattccctg aattaaacca aacattagaa gaactagcag ctaaatatca
    11401 aacgacacca actggcttgg cttctgcttg gattttacgc catccagcca atatgcaagt
    11461 gatcgccggt acgatgaacg tagggcgaat caaggaaatc gctcaagctt cagaaattaa
    11521 tatgtctcgg gaagattggt acgaattgta ccgtgctgct ggaaacattt taccttaaag
    11581 attgtcataa gcaggtcaaa agggctataa attaaaaaga cagaataact tgaaagctgt
    11641 tttcagcttc gagatattct gtcttttttt attgcaaatg gaaagagtat cattgtacgg
    11701 atttcgttta ttagttattt ttgtttttaa ggaaaagctg tgtccgatat tcttttggag
    11761 aaatcccttg ttttttctta aataaataac tgaaatagtt agggtcatta taaccaattt
    11821 caaaagcaat atctgaaata cgatagtctg attgctgcaa taattttttt gctaattcga
    11881 ttctttgttc tgtcagataa tcgatgaatg tttggttaaa cgattgagaa aaaatcgtac
    11941 tgaaatgaga gggacttaat gcaacttgtt gagcgaccca agttaaggac atatctggat
    12001 cggtaaaatt ttctttgata aaatccaatg catggttcaa aattggctga tatttgttcc
    12061 ttgaaggctg tgagggcaga gcagttaaga aagaaatgaa catataaact gtcgaacggt
    12121 aaagcgagtc gtcggcgctg attgctaagc gttgactggt ggatgtgcaa tgaaccattt
    12181 cttgcgggat tttcttttct ttcaggcaga catgctggag tagcttagtc aagacaaata
    12241 aacgatataa tcgtgttcga gttggtgtgc cttgtggttt cgtcaagtgt tcgatgtact
    12301 tagatacttc gtttttcgat aatgaagaca aatcaagtga gaggtcaaag taaaagacag
    12361 aatcaactgg aagtttcgct tcttgaatca aatcctcata gctgataatt tgttctttaa
    12421 gggaactggc ggtttcaagt atcatctgcg tgatctcaaa agatgcaggt aattcgctga
    12481 ttctttctgc gacaggacca atggcgacag aaaaattatt tttttgtccc ttttctaatt
    12541 catggaccaa cgtttgggct acctgataac tggtctcgat cacattttct tcaagagaat
    12601 caactattaa aaatttgatg aatcgagagg aaacagcaga gaagatcact tgttgattct
    12661 ccctaaataa aaacttcaaa taatcactga gatgagcgta atcttcaaag tctgtactga
    12721 cttggtttgc tgctaataat acggtcattt ttttccctgc taaagagcga ttgaaagatt
    12781 cagcaagttt caatgtttca ctgatcgtaa gtgagccttt gaacaaaccg ttcaagaaat
    12841 gatttttttt caattcgaaa acaagatcag aagaagtgtg cgtttctttt tgctgcaaat
    12901 ctaaagcagt tactgctttt tctattgctt gtttcaattc gctactttta atcggtttaa
    12961 gcagataatc atctgcctgt acctggattg ctcctttcat ataatcgaaa tcgtcgaatc
    13021 cactaataaa tatgagacga gtccaaggaa gtagtttcct tgcttctttt gaaaaagtca
    13081 acccgtccat gaaaggcatt tggatatcag tcagaatgat gtcgggctgt aagtcgataa
    13141 ttgaagacag tgccatctca ccatctccag cttcgccgac ataagtgatt ggataataag
    13201 aaccaaggac agttatttgt tcccgcaagt tattgcgaat gaggtattcg tcttcgatga
    13261 taaaaacttt atacatgttt gtttcctcca attgttttgg gagatagagg gatcatcagt
    13321 gtgacagttg ttccttctcg gtatttgctg tcaatcgtga taggtttttg atcatttccg
    13381 taataaagaa ggagacgctt gtttacgttg taaagtccgt agccgatact gaaatctgaa
    13441 tcgatccctt tggctaactc tttacgtatt tctgccagtt tttctgcagg gatgccaatc
    13501 ccgttgtcta taactttgaa ttggatcatc tcatcaattt tgcatgtggt aatacgaata
    13561 aatcctttgt gacggacgta cttcgttcca tggtatacag cattttcaat caatggctgc
    13621 aagatcattt ttaaaataga aacaggaaaa agtgtttctg gtatatcgat cttatagtca
    13681 agcatatggc cgtatcttat ttttaagatg actagataat cattgatatg gctaatttct
    13741 ttttcaagag gaatccagtc ttgtcctttg cttaaagacg tacgaaaaaa gccggaaagt
    13801 gcatgggtca tagtcagagc ttcttcaaag cagtcttgtt cgatcaaaga aataatggca
    13861 tccaaactgt tataaataaa atggggagta atctgagctt gcaatacacg aacttcactt
    13921 tgtgctaaat ggtattgttt caaagcgttc tcccgtaaag actggtttag atcttccgcc
    13981 attttattca tgctagcggt aagtgtttgt aattccagtg tttccggcag ggttaaacga
    14041 aagccaaggt tccctgaaga aagttgttct gacatctcga tcagctgatt gatcggttct
    14101 tggacctttc tctctaaaaa gcgacgattc tttttcgcat agaaaaaaat ggtactaaga
    14161 actccaagtt ccactattgt taatagaatg agcgagcgga caagtgtcgt attttttttg
    14221 cttgctaagt cgatctccac acgaacaaaa tcttgtaaga tatctgacag cagttgagtg
    14281 acagaatcta cctgattgat gatctcttca ttggtatcca taaaatcttt tgccaagata
    14341 ttattgatca gctcgttttg ataatcttcc agtgtatcga tcgtacgtag cgatacatct
    14401 aacgtactaa tttctttaag tgtatttgta ttatttttga tctctcgaat atcattccta
    14461 agttcttcta ggatattttc ctcattgaac tcatctacgg ttacttggcc agaaatcaag
    14521 tcccacatac tttccaaaac tttttgatca accttcaaag caattgcatc tgctttttgg
    14581 atatttgcga tcgtctgttg ataaatcaaa agctgttgcg aatataacag tatgctcagt
    14641 agcaaaggga taacagcaaa tagaagcatg gctttgtttg cttgggcaaa aatctgtttt
    14701 atgcttaaat tttttgtcat gatacttctc cagtcaataa tttctggttg ggatgttagc
    14761 tatattctgc tgggaaaaga cagtctcgga aataaaaata tctttaggta atgtttttcc
    14821 tgtttgaata tttccaaaat aacgagtaac ggtattggct acataccagc cgacatcagg
    14881 tttacactcg actacacaat tgacgattcc tgagcgtagc ttctcgatca tatcttcttg
    14941 tccatcaata gttacaatga tcaaatcttc tccaggtttg attgatgttt cttttatcgc
    15001 agctaaagca ccgtgagtca tttcatcact atggctgtat aatacatcga tttcggataa
    15061 atcatttgtt tctaaatatc gtttcatctg gtcttttcct ttcatccgaa taaaatcacc
    15121 gacaattcgg tgaacaatag tcatcggagg tttatggtcg atggttccat ctttttttag
    15181 ggttggttta cgattgattg attccaaaaa tccttcggag cgtagcttgg tcggtgtgga
    15241 gttctctgaa ccagcaagtt ctaggattct gatttcctgt ttctttgaat ttgtgaagtg
    15301 attgctgaca aataaacccg cccgatttcc ttctgctttg aaactggggc caatgtgggt
    15361 gacgaaaagc tcgggatcat tcgtttgaat atgtctgtcg acaagtatga cagggatccc
    15421 tgctcgcttt gcttctttta atacagagtc ccacccggat tcttgcaaag gagtaaaaat
    15481 gatcatatcc actttatagg caatgaacgt ccgtatatct tggatttgcc gttcctgatt
    15541 catgtagcca tttcggtaga gaacttggta atcttctttt tcaagcgcag tgataattga
    15601 ttcagtatgc tttttccgcc agctactctc cgttcctgat tgcgaaaaac caacgactag
    15661 tgggtcaggt gcttcctttg tattaggtgt acaccccatc atttggtaag cgattacaac
    15721 aagggctaaa aaaaataaaa cacgtttcac tttaaatcac tccatctgga tttgttagta
    15781 ctatcttatc agataaaagg gaaaatcaaa gtcaaaagga atcaatcgaa aaaaatccaa
    15841 gaaacttaaa aaaatccaag acaaaaaaag tacacctaaa aaatttaaag taaatcccat
    15901 aaaaaaatca atgttaacgc tttctttatt agctatactc ggtgtatcaa ttgaaatggg
    15961 ggataaaaaa tgaaaaacaa atttagaaag attgttggga ctatcgctat tttgaccgca
    16021 agcattctat taagtgcgtg tggcaattca ggatctgcag atgatagtac ggggtatgta
    16081 ggaatcgcta tgccgaccaa atcagcagaa agatggatcg ctgatgggaa caacatggtc
    16141 tcggaattag aaaaactggg ttataaaaca gatcttcaat atggagaaga taaagtagaa
    16201 aatcaagtag cacaaataga aaatatgatt acaaaagggg tagatacact tgtgattgct
    16261 tctatcgatg gttcggcttt aactgatgtg ttagctaaag caaaagaagc agatatcaag
    16321 gtgatcgcct atgatcgttt actgatgaat tcagaaaatg tcgattatta cgcgactttt
    16381 gataattttg gagtaggtgt atcgcaagca gcttatattg aagagcactt aggattgaaa
    16441 gaaggaaaag gaccattcac gattgaatta tttggtggct cgcctgacga caacaacgca
    16501 ctaatcaatt acaacggagt gatgtctgtt ttacaaccat atatggacaa cggtcagttg
    16561 gtcgtgccat ctggacagac gagtttcagt caaatcgcta cgcttcgctg ggatggttct
    16621 acggcgcaag caaggatgga taatctgtta agcgcaaatt atactgacca aacattggat
    16681 gctgttttgt cgccatatga tccaataagt ttaggaatca tttcgtcatt aaaaggcgtg
    16741 gggtatggga gtgaaagtaa acctttacct gtgattactg gacaagatgc gacagttgct
    16801 ggcgttaaat cgatcattgc cggggaacaa acacaaacga tctttaaaga cacacgtatc
    16861 ttagcaaaaa atacgattga aatgatcaaa gcaatcagtg atggagaaga ggttccggtc
    16921 aatgatactg aaacttatga taatggggtg aaaactgtcc ctacgtattt agcaaataca
    16981 gtatctgtcg ataaagataa ttatcaagca gagctgatcg acaccgatta ttataaagaa
    17041 tccgatctga aaaattaaga ggaaccaaac aaggaactaa agagatctaa gtcagagaga
    17101 ggataagaat tatggcggat tgtattttaa aaatggcaga tatcaccaaa aaattttctg
    17161 gaatccgagc gttagattgc gtgaatctga tgattgaacg tggggaaatc catgcattgt
    17221 gcggagaaaa cggagcggga aaatcaacat tgatgaatgt cttgagcggc ttgtatccat
    17281 atggctccta tgacggggaa atcttttatg atggaaagct gtgtcaattt aaagatttga
    17341 aagatagtga agaaaaaggc atcgtcatca ttcatcaaga attagcacta agtccttatc
    17401 tttcaataaa agagaatatt tttctcggaa atgaacaagc agaaagaggc gtgattgatt
    17461 gggaactgac agaaaagaaa acatatgaac tgctgaataa agtcggtttg tctatcgacc
    17521 cgaatcttct agtatcccag attggcgtag ggcaacagca actagttgaa atagctaaag
    17581 cattatcaaa atccgtccgt ctgttgattt tggatgagcc taccgctgca ttgaatgaag
    17641 aagaaagcgc gaatttgctg agattgatcc gagagttgaa agagcaaggt gtaacctcca
    17701 tcattatttc acataagctg aatgaaatcg tggatatcgc agatcgaatc accattttac
    17761 gggatggaca gacgattgag acactagaaa atgaaatgat cagcgaagag catattattc
    17821 gcggaatggt gggcagagat ttagttgatc gttatcctga aagaaaaccg gatattggag
    17881 aagtttattt taaagtagaa gactggacgg tctatcaccc tcttgatcac gagcgaatca
    17941 taaacgacca catcaacttg catttgaaaa aaggagagat tgtaggaata gctggactga
    18001 tgggagcggg cagaactgaa ttcgctatga gtctatttgg acattcttat ggaagcaaga
    18061 tatccggacg tatattaaag gaaggggcag agatatcagt taagaccgtt ccttcagcca
    18121 ttgcaaacgg actcgcttat gtctcggagg accgaaaatc tttaggactg aatctgctga
    18181 tggatattcg ggaaaacgtg acgctgagca gtttggataa aataagtcaa aaaggagtat
    18241 tagataaaga aaaagaagta actgaggcag aaaatttccg gaaaaagatg cgtataaaaa
    18301 caaactccat ccatcaaatt gtcagtagtc ttagtggtgg gaatcaacaa aaagtcgttt
    18361 tatccaagtg gctgatgaca caacccgata ttcttttttt ggatgagcca acccgtggga
    18421 tagatgttgg ggcaaaatat gagatctaca cgattatcga agaaatggca gcaaatggca
    18481 aagctgtctg tcttatctct tctgaacttc ctgaaatatt agggatgtgt gatcgaatct
    18541 atacgatgaa cgaaggacgt attacaggag aagtctcgcg agaagatgca gatcaggaag
    18601 tcttgatgaa attaatgacg aaagaagagg tgggttaagt tggaacaggc aaaaaatctt
    18661 acggataaaa aagagaaaaa actaaatttg aaaagtagag cagctgatct ttttggtcgc
    18721 tacagcatgg tgatcatttt agcgggacta cttattgcgt ttcaattgat gacggatggt
    18781 attttctggc gtccattgaa tataactaac cttgttctgc aaaatagcca tatattagta
    18841 ctagctgcag ggatgttatt agttgtgctc ttaggtcatg tggatttgtc ggtagggtca
    18901 gtgatggcgt ttgttggtgc aattgcgggc atgatgatgg tcaatcgcca aatgaacccg
    18961 tggatgacag ttatcgcatg tcttgcagta ggcgggctga tcggcgcatg gcaaggtttt
    19021 tgggtagctt atgcagggat accggcgttt atcgtgactt tagcaggatt gctgatgttt
    19081 cgtggactga cacaagttgt tctaggaggc caatctctag caccttttcc agctgttttc
    19141 caaaaaatgt ctacgggtta tttaccagac ttaagcgaag gaagcagcct tcacttcttg
    19201 acattgattt taggaatgat catcacgatc gtgttagttg ttggtcaatg gcgaacaaga
    19261 aatcgtcgga aaaatcattt atttgaagtg gaatctccaa cagctttctt ggtaaaggcg
    19321 gtatttacag cagtcgttgt actaggaata acttatatct ttgcctctta tcaagggtat
    19381 ccgattattt tgatcattct tggtttgatc gttgcagcat atgggttttt gacaaataaa
    19441 acagtagcag gtcgacagat ttatgcgacg ggcggaaatc gaaaagcggc tgaactatca
    19501 gggatcaaaa caaagcgaat cacgttctgg gtattcgtca acatgggagt catggcagct
    19561 ttagctggat tagttttagc tgctcgattg aatgcggcaa cacctcaagc aggtacatcg
    19621 atggaactgg atgcaatggc ggcagtatat tttggtggtg cttcgacttc cggcggcatt
    19681 ggaacaatca tgggtgcgat tgtcggtggc ttggtcatgg gtgtattgaa caatggcatg
    19741 tcgattttag gcgtcggggt agactggcag caggcaatca aaggattgat cttgctttta
    19801 gccgttgtgc tagacttgta taataagaaa aaacgaacaa cgtaggagaa cgccggttat
    19861 tcagaaaaaa gactgtgaca agacatttgt cacagtcttt ttttcgctaa aagcgaacat
    19921 tcattgtttc gtttgtatag actaaaaata atatatgttt ttttaccatt cgtataaatt
    19981 ctctttttgc tcttgatttt tttgcttaat tgagttaaat tacatagggc gctaaaaaaa
    20041 gccttgatta aattaataat gttcgtgttt tgctggatgt gaacatcagg aggataatgt
    20101 aatgaaagta tttgattacg aagatattca attaattcct aataaatgta tcgtaaatag
    20161 ccgttctgaa tgtgatacaa cggtcacatt aggtaaacat acattcaaaa tgccagtagt
    20221 gcctgccaac atgcagacga ttattgatga aacaatcgca gaattcttag cggaaaatgg
    20281 ttatttctat atcatgcatc ggtttgatga agcagctcga attccgttta tcaaaaaaat
    20341 gaaaaagcgt ggattgatta cctcgatcag tgttggcgtc aagaaagagg aatattcctt
    20401 tatagagaag ttggcagaag aatcgctaaa tcctgattat atcactatcg acatcgcgca
    20461 tggacatgct aactcagtta ttgatatgat tcagcatatt aaaaaatatt tgcctgaaac
    20521 ttttgtgatt gccggtaatg ttggtacacc ggaagccgtc cgtgaattgg aaaatgcggg
    20581 cgcagatgca acaaaagtcg ggattggtcc aggaaaagta tgtattacaa aaatcaagac
    20641 aggctttggg actggaggct ggcaactggc agctcttaga tggtgtgcga aagcagctcg
    20701 caagccgatc atcgctgacg gtgggatcag aacacatggc gatattgcaa aatctgtccg
    20761 ttttggtgcg acaatggtca tgattggttc attgtttgcc ggtcacgagg aatctcctgg
    20821 cgaaacaaaa gtcgaaaatg gaatcgtgta taaagaatac tttggttctg cttcagaatt
    20881 ccaaaaaggc gaaaaacgaa atgttgaagg aaagaaaatc tggatccaac acaaaggatc
    20941 tttgaaagat acactagtgg aaatgcaaca agaccttcaa tcatctattt cttatgctgg
    21001 aggaagagat ctggaagcca ttcgaaaagt tgactatgtc atcgtgaaaa attcgatttt
    21061 taatggagac acaatctaaa aaataaataa aatattagga tgttgtgaaa aagttgtcct
    21121 gcattaagta ataagaacag ccaaacaaaa atagttcttt atatgttttg tttggctgga
    21181 attattatcg cagatacaag cttttgaaca tcattattca gaataaggga ctgtgataag
    21241 atttttgtca cagtccctta tgttttgcaa aaaaagtttt tcttttttct cgtaaattcg
    21301 gtaaaatcaa aagaaaaaat agacaataga aaagagaagc ttatgtggga aaaagtagag
    21361 aaaaaacaag gaccgattta tcgtcaaatt atggaacaga ttatgagaga aatcgaaaac
    21421 ggaaggatca atcctggaag tcaacttgaa tcagaacgaa aactagggca actttttggt
    21481 gtgaatcgtt ccaccgttgt ccatgcattg gaagagctta gggagcttgg ggtactaacg
    21541 agcaaacgtg gcagcggatg gtttgttaat cagactgaat gggggaaatt cgctgttcca
    21601 agaatcgatt ggcggcaaat gatctctcct cgttatgagc agacggactg gtatgagcaa
    21661 aaaataagag aagcaaagca gatccaaaaa acatcgtttc ttgatttata cgctagcgag
    21721 atgccagatg agcttttgcc gaattttgag tttccttctt attctcttga agaaatctta
    21781 gcggaagaaa aagaaatgga tcttttaggc tatactccgt tacgtaacaa aatcaaacgg
    21841 tatttggaaa gtaaatttga attggcattt tcccccaacc agcttcttgt gactggtggc
    21901 ggtcagcaag caatcttttt gattttacaa acgattcttt cagctggaga ggggatagct
    21961 gtagagtcac cttctttttt ttaccgatta cctcttttca aagcttcagg aacgcgttta
    22021 tttgggatac cgatggatga agaagggatc gacttagaaa aactgaaaga atcgatccat
    22081 aaaaataaat tgaaagcagt gcttatcaac ccgaattttc aaaaccctac aggaaaagtg
    22141 atgagtcaaa aacgacgaga aaagctagta gaattgtgtc gacagtatcg gcttccaatt
    22201 attgaagacg atgtatttac ggatctttca tttctaaacc aagaagaagt ccttcctata
    22261 cgaacgattg atccggataa tgtgttatac gtcggttcgt tatctagggt tttaggaaaa
    22321 acaacgaaaa tcggttgggt gataggacct gagactttta tctcgcaact agctcaagcg
    22381 caagaaatga tggagttttc gatgaatatc cttacacaaa tcacagtggc taatgtattt
    22441 aatgaagcaa ttgatttgaa aatgcaagat gtaagaaaaa agttgaaaga aaaaagccga
    22501 ctgataagcg cttggggaga ttcacaatcg tttttcaagc ttcattcaat tttaggtggt
    22561 tactatgcct ggattacttg ggatgggaaa aaactagacc ccgaactagc agaaaaagta
    22621 gtagatatgg gtcttggaat tgcaccaagt ctactttttg ggcaagatat aaatggaatc
    22681 agaatcaatt acagtaggct ggatgaaaac caaataccgt tgttttattc aaagatgaaa
    22741 attctagaaa agtggttaac agaataattt cacaaagtaa atagattaaa gaatataaca
    22801 gcttggattt aaatttcaag ctgtttcttt tttttcggaa aaagaatacg atataaagaa
    22861 actaagaaaa aaccattatt tgtacgtccg ttcacgatgt gtaaataaaa taaatgtttg
    22921 caacaaaact gtataacacc aacgttttta aatagaaaca gatggttgta agtttgatta
    22981 gaaaatagaa aaaatgcaga tgaaatataa aacgctttcc ttattgtgat tttattcact
    23041 aatgctgtta atatgcggat tggcataatt tcctttcatc gtgaaaattt gtgcttttag
    23101 cttgtatttc tcataaatcc atgataattt attaatgaag acggttaaat agtgatacag
    23161 ttttattcac tgtttcaatc gcagaatgaa gagattttct tatagatgag agaggaatgt
    23221 gtgacaaatg gcaaacaaaa aagcaccgat cgacttccaa gcactgctag atgaagtcaa
    23281 tgcagatttc ccagtatatc aagcacttga tcaagatgga aacgtagtta acaaagattt
    23341 agtacctgat ttatccgatg atgaactcgt tgaattaatg actcatatgg tatggtctcg
    23401 tgtattagac caacgttcaa cagcgctgaa ccgccaagga cgcctaggct tttttgcacc
    23461 aactgctgga caagaggcaa gtcagctggc tagtgcttac gcatttgata aagaagatgt
    23521 tcttcttcca ggttatcggg atgtacctca actagtaaaa catggtttac ctttatctca
    23581 agctttttta tggtctcgag gacatgctgc aggtaattct tatccggaag aattgaaagc
    23641 tctaccacca caaattatca tcggtgcaca atatgtacaa gcagccggtg ttgcattagg
    23701 tttgaagaaa cgaaacaaga aaaatgtcgt cttcacttat actggtgatg gcggttcatc
    23761 acaaggtgat ttttacgaag caatcaattt cgctggcgct taccatgcaa atgccgtatt
    23821 ttatatccaa aacaacgggt atgcgatctc tacacctcgt gaaaaacaaa ctgcagcaaa
    23881 aacacttgca caaaaagctg tcgcagctgg gattcctggt attcaagtcg atggaatgga
    23941 tccgcttgca gtatatactg tatctaaaat ggcacgggaa tgggcgatca gtggaaatgg
    24001 accagtccta atcgaaacac tgacttatcg ttatggacca catacactat ctggtgacga
    24061 tccaacccgc taccgtacaa aagacacaga tgacgattgg cagaaaaaag atccattgat
    24121 ccgcttccgt aaatatttga cggaaaaagg actttggtct gaagaaaaag aagaacaagt
    24181 catcgaagca actaaagaag aaatcaaagc agctattgct gaagccgaca aagtaccaaa
    24241 acaaaaggtt tcagatttct tgaaaaacat gttcgaagta tctccacaat caatcaaaga
    24301 acaaattgca atttatgaag cgaaggagtc gaaataatca tggcacaaaa aacaatgatc
    24361 caagcaatca cagatgcctt agcacttgaa ctagaaaatg acgagaatgt cgttgttttt
    24421 ggtgaagatg ttgggaaaaa cggaggagtt ttccgggcaa ctgaaggatt gcaggaaaag
    24481 ttcggagaag accgagtatt cgatactcct ttagctgaat ctggaatcgc aggattgagt
    24541 ttcggtcttg cgttagaagg atttcgtcca gttcctgaaa tccaattctt tggttttatt
    24601 ttcgaagcaa tggacgaagt agtagctcaa atggctcgta caagatatcg aatgagcggc
    24661 actagaaatc tacccatcac aattcgttcg ccatttggtg gcggtgttca tacaccagaa
    24721 ttgcattcgg ataatttaga aggtttgatc gctcagtctc ctggtattcg agtagtgatt
    24781 ccttccaacc cttatgatgc aaaaggacta ttgatttctt ctattagaag taacgatccg
    24841 gttgttttcc tagaacacat gaaactatat cgctcattcc gagaagaagt gccggatgaa
    24901 gcttacgaag ttcctttgga taaagcagca gttactcgtg agggaacaga tgtatctatt
    24961 atcacatacg gagcaatggt gcgtgaagca atcaaagcag cagacaatct tgcaaaagaa
    25021 aatatatctg ttgaaatcat tgatcttcgt acagttgcgc cattagatgt agaaacgatc
    25081 attcaatccg tggaaaaaac tggtcgcgta gttgttgtcc aagaagcaca acgacaagcg
    25141 ggcgttgccg cgcaagtagt ttctgagatc tcagaacgcg ctatcctttc attagaagcc
    25201 ccaatcggac gagtttctgc acctgataca gtcttcccat ttggacaagc agaaaatgtc
    25261 tggttgccaa atgcaaaaga tatcgaagac aaagtaaaag aaatcgcgga attttaagaa
    25321 aagaagggac gaaacaaagt catggcttat caatttaaat tgccggatat cggtgaagga
    25381 atcgcagaag gtgaaatcgt caaatggttc gtcaaaccag gagatacgat caatgaagat
    25441 gatacattac tagaagttca aaatgacaaa tcagtagaag aaatcccgtc acctgttaca
    25501 ggaacggtta aaaatgtgat tgttccagaa ggtaccgtag caaatgttgg ggatgtatta
    25561 gtagaaatcg atgcaccagg acacgaagac aatgaagggg acagtggtgt agccgcagaa
    25621 tcccaaactc cagctaaacc ggctgctgaa cccactgttg atacagaatc agctggatcg
    25681 tcaagcgaag gagtcttcca atttaagtta ccggatatcg gtgaaggaat cgcagaaggt
    25741 gaaatcgtca aatggttcgt caaaccagga gatacgatca atgaagatga tacattacta
    25801 gaagttcaaa atgacaaatc agtagaagaa attccgtcac ctgtcacagg gacagttaaa
    25861 aacgtgattg ttccagaagg cactgtagca aatgttgggg atgtattagt agaaatcgat
    25921 gctcctggac acaatagtgc accgtcaact agtgcgccat cagctgaagc accaaaagaa
    25981 aaagtggaaa catcaggttc agcaagtgtc gttgaagctg ccgatccaaa taaacgtgta
    26041 ttggctatgc catctgttcg tcaatttgcc cgtgaaaaag atgtagatat ctcacaagta
    26101 actgcaactg gaaaaggtgg cagagtaaca aaagaggaca tcgaaaactt cttggcaggt
    26161 ggtccaagca gtgcaccagc gaaatcagaa gcgccagaag cggcagcacc gaaagaagca
    26221 gctcctgcag cagaaagcaa accagctgca ccagcaaaac cattcaagtc caacttagga
    26281 gacttggaag aacgtgtagc aatgacgcca acacgtaaag ctatcgctaa agcaatggtc
    26341 aacagtaagc atacagctcc acacgtgaca ttgcatgatg aagtagaagt gtctaaacta
    26401 tgggataatc ggaaacgatt taaagaagtt gctgctgcaa atggtacgaa acttactttc
    26461 ttgccatatg tcgtgaaagc tttaacagcg actgttaaga aatacccagt attgaatgca
    26521 tctatcgacg atgcaaacca agaaatcgtt tataaacatt actacaatat cggtattgca
    26581 actgatacgg atcacggact atatgtacca aatgtgaaag atgcagaccg caaaggaatg
    26641 tttgctattg cagacgaaat caatgagaaa gcaaaattag ctcatgacgg caaactatct
    26701 gcagaagata tgcgcaatgg aacaattacg atcagcaata tcggatctgt aggtggcggt
    26761 tggtttacac cagtcatcaa ctatccagaa gtagctattt taggtgtagg aacgattgca
    26821 caacaaccaa tcgtaaatgc tgaaggcgaa atcgttgtcg gtcgtgtgat gaaactgtca
    26881 ttaagtttcg atcaccgtat cgtagatgga gcaactgcgc aacaagcaat gaataatatc
    26941 aaacgtcttt tagctgatcc agagctatta atgatggaag gatgataaac aaatggtagt
    27001 tggagatttt gctgtagaat tagatacagt tgtaattggt gcgggacctg gtggctatgt
    27061 agctgccatc cgcgctgctg aaatgggaca aaaagtagca atcattgaaa gagagtatat
    27121 tggcggtgtt tgtttgaatg tcggctgtat tccttcaaaa gcactgatag ctgcaggaca
    27181 ccattatcaa gagtcactag attctgaaat gtttggagta actagtgaaa acgtcaaact
    27241 agattttgca aaaacacaag aatggaaaga aaacaaagtt gtccatacgt tgacttctgg
    27301 tgttggtttc ctattaaaaa aacataaggt tgaaacaatc gaaggagaag cgttcttcgt
    27361 agatgatcac acactacgcg tcattcatcc agattcagct caaacttatt cgttcaataa
    27421 cgcaatcatc gcaacaggtt cccgtccaat cgagattcca ggatttaaat tcggaggacg
    27481 tgtgttagat tctactggcg gattagcatt gaaagaagta cctaagaaat ttgtgatcat
    27541 cggtggcggt gtgattggtg ccgaattggg cggagcgtac gcaaacttag gagcagaagt
    27601 aacgattctt gaaggctcac cacaaatttt accaacttac gaaaaagatc tagtaaaatt
    27661 agtagaagat gatttcaaga aaaaaggcgt aacagtcgta acgaatgcaa tggcgaaaga
    27721 agcagtcgat aacggtgaca gcgtgacagt gaaatatgca gtggacggga aagaagaatc
    27781 cgttactgct gattatgtga tggtcactgt aggtcgtcgt ccgaatacag atgatatggg
    27841 cttagaacaa gcgggtgtcg aagtaggaga acgaggattg atcacggtgg ataaacaagg
    27901 acgtacgaac gtacctaaca tctatgccat cggtgatatc gttccagggg cggcattagc
    27961 acacaaagcc agttatgaag caaaaatcgc tgctgaagca atctctggca aaaaagtagc
    28021 tgtagattat aaagcaatgc cggcagtagc cttcactgat cctgaattgg cttctgtagg
    28081 tatgacgatc aaagaagcaa aagatgctgg tatcgaagca aaagcatata aattcccatt
    28141 ttcagggaac ggtcgggcat tatcgcttgg taaaacagaa ggattcatcc gtctagttac
    28201 gacgatcgaa gataacgtgc ttattggcgc gcaaatcggt ggagtcggcg caagtgatat
    28261 ggtctctgaa ttagctttag caatcgaatc aggaatgaat gctgaagata tcgccttgac
    28321 gattcatcct catccatctc ttggcgaaat cgtcatggat gcttcggaat tagcattagg
    28381 tttaccaatc catatttgat ttgaataata caggcgaaac gcaactgaaa aatcagttgc
    28441 gttttgtttt ttagaattat caataatatt attatgtaaa cttaaaaata tgacaacttc
    28501 ttggtttatt accacttcct atgctacact gaagaggaat atgaaatagg agagttgaag
    28561 atgcaagaat atcagtatcc acttgattta gattggacaa cagacgaaat ggtcattgta
    28621 atgaagatgt gggaagatct ggaacgtgcg aatgaaaaag ggataaacaa tgaagctttt
    28681 ttgaagactt atcagcagtt taaaactgtt gtcaaatcca ttggtgagga aaaacgattg
    28741 ggacgggaat ttgaaaaagc ttccggttat tctttatatc gtacagtgca gcaagcaaaa
    28801 aaaaatccaa acaaaacttt gagaatgaac gggtgagata aatggaacag atgattgatc
    28861 atatcaagtc ctggcttgaa gaagctggtg agaaaatcaa atcttctcaa caaacattaa
    28921 caatctcgca aaaatcaaat cgaacggatc tagtaacaaa tgtcgatcga aacatccaga
    28981 attttctaat cgaaaaaatc cattcctttg atccagaggc gaaaatattg gcagaagaag
    29041 aagggtgtaa tcaattatcg gatctcgatg gaagagtctt tatcatcgat cctattgatg
    29101 gcaccttgaa ttttgtgatt gaaggggaaa atttttgtat tatgctcgct gtttatgaat
    29161 ccggcgttgg aaagcttggt ttcatttatg acgtgatgag aaatgaactt ttttggggtg
    29221 gaaaaggaat aggcgtgtat aaaaatgatg agccattgcc tagaccagca aataaatcct
    29281 tatcggaagg cttacttggt gtgaatagtt atcttttcgg tcataataaa tatggaatcc
    29341 gagaaattgc ggaaagcagc atggggacac gtatgtacgg atgcgctggt cttgaactag
    29401 tggcaatctt gaaaggaaac cacattgctt atatttcaaa ccttagccct tgggattatg
    29461 cagcgggaaa tgtcttattg gaagagtttg gtatggtaac aagcggtctt tttggtactc
    29521 ctttgacatt tgaaaaaagg gaatactatt tagcagggac ttcttgtgca tatgcagaaa
    29581 tcgcagacct tttgaaaaaa gaaggctgaa aaaaaggtag aaatcattca caaaaatgat
    29641 aaaaacgagc aaaagattaa ttttctcgaa aaaatgaaaa cattttacta tatttcatga
    29701 aaaaagtctg ctataattag cagtcgagta aaatttgccc tgtcataaag aaccaataaa
    29761 aaaggagtta gttacattga attatagaaa cgatatccgt aacgtcgcaa ttattgccca
    29821 cgttgaccac ggaaaaacaa cattagttga tgaactatta aaacaatcag atacattaga
    29881 cgcacatacg caattgcaag aacgtgcgat ggactcaaat gcgctagaaa aagaacgtgg
    29941 tatcacgatt ttagccaaaa acacagctgt agactataaa ggtattcgcg taaacatcat
    30001 ggatactcca ggacacgcgg acttcggtgg cgaagtagaa cggatcatga aaatggttga
    30061 cggcgttgtg ttggtcgtag atgcgtatga aggaacaatg cctcaaacac gttttgtatt
    30121 gaaaaaagca ctggaacaac atatcacacc aatcgttgtc gtaaacaaga ttgacaaacc
    30181 ttctgctcgt cctgagcatg tcgtagatga agttcttgaa ctattcatcg aattaggagc
    30241 agatgatgat cagttagact ttcctgtgat ttatgcatct gcactaaatg gtacgtcaag
    30301 cttgtcagat gatccagcag atcaagaacc aaccatggca cctatttttg atacaattat
    30361 tgaaaaaatc cctgctcctg tcgataacag cgacgaacca ttacaattcc aagtttcatt
    30421 acttgactac aacgattatg taggtcgtat cggaatcgga cgtgtattta gaggaacaat
    30481 caaagtagga gaccaagtag cattaattaa attagacgga acagttaaga aattccgtgt
    30541 aacgaaatta tttggtttct ttggactaaa acgtctagag attcaagaag caaaagctgg
    30601 agacttgatt gctgtctcag gtatggaaga tatctttgtc ggtgaaacag ttactcctgt
    30661 ggatcatcaa gatgcgttac ctatccttca cattgacgaa ccaacattgc aaatgacttt
    30721 cttagttaat aattcaccat ttgccggtcg agaaggtaaa ttcgtaaccg ctcgtaagat
    30781 tgaagaacgt ttgatggcag aacttcaaac agatgtatcc ttacgagttg aaccaacaaa
    30841 ctctccagat gcatggacag tttctggtcg tggagaattg catttgtcta tcttgattga
    30901 aaacatgcgc cgtgagggat acgaattgca agtatctcgt ccagaagtta ttgaaaaaga
    30961 aatcgacggt gtaaaatgcg aaccgtttga acgcgtgcaa atcgatacac cagaagaata
    31021 tatgggtagt gttatcgagt ccttgagctt acgtaaaggt gaaatgcaag atatggtcca
    31081 tacaggaaac ggacaaatcc gtttgacatt cttaacacct gcccgcggtt tgattggtta
    31141 ttcaactgaa ttcctttcaa tgacacgtgg ttacggaatc atgaaccata cttttgacca
    31201 atatctgcca atgcttcctg gtcaaattgg cggacgtcac caaggggcgc ttgtttcgat
    31261 cgatacagga aaagcaacga cttattctat catgagtatc gaagaacgcg gtacagtctt
    31321 cgtagaacca ggtacagaag tatatgaagg aatgattatc ggggaaaaca gccgtgataa
    31381 tgatttgact gtcaacatca cgaaagcaaa acaaatgaca aacgtacggt ctgctactaa
    31441 agaccaaaca tctgtcatca aaaaaccaaa acaattgacg ttggaagaat ctttggaatt
    31501 cttgaatgat gatgaatatt gcgaagtaac accagaaagc attcgcttga gaaaacaaat
    31561 tttagagaaa aatgctcgtg aaaaagcatc taaaaagaaa aaataatctg taaaaggatg
    31621 aagagagaaa ccagcttgtt ataaaaaata gctggtttct ttttttgtcc aactcttttc
    31681 tgtggagaag tcatctttgt caatggacat aaattcagaa aatacgccga aagacgttta
    31741 aaagactttt aaaaaactta tttctagaga gtttttgttt cataataaga taatgtttca
    31801 cgaaaggaga tcaacttgtc cttcgaagaa aatcgaagta aaatggcaag agaaaggagc
    31861 gggaagatga acgacttatt aaaacaatac tttggctatg atgagtttag acctggtcaa
    31921 aaagaaatta tccagaaagt cattgatcag gaaaatgtat taggaatcat gcctaccgga
    31981 agtgggaaat caatctgtta ccagcttcca gctttactat tagatgggct tactgtggtt
    32041 gtgtcccctt taatctcttt gatgaaggat caggtggacg cggcgaatca attaggtata
    32101 cccgccactt ttatcaatag ctcgttagat ggttacgaaa cagctagacg cttccaagaa
    32161 atcgatagac agcagtaccg tttactttat atcgctcctg aacgttttat catgccggat
    32221 tttatccaag caatgaagcg atggaacgtc cgtatgatcg ctattgacga ggcacattgt
    32281 atctctcagt gggggcatga tttccgccca agttatttac agatggcgaa ccagctagat
    32341 caactgccaa atcgtcctgt aattgttgct ttgacagcta cagcgactgt gcaagtagct
    32401 gctgacataa aaagactttt aaaaattcca gaaaacaacc atattcagac tggttttgaa
    32461 cgagaaaatc tacgatttca agtaattaaa gatcaaaaaa aagaacaata tctaatcgaa
    32521 tatttaaaga tcaacaaaaa tcaatctggt atcatttatg cagcaacgag aaaagaagta
    32581 gaccgtctct atcatttgct taaaaaattc gatttttccg tgggtagata tcatggtggt
    32641 ctaaatgaga atgagcgaac agaaatgcaa gaagcctttt tatacgatcg cttgcagctg
    32701 attgtagcga caaatgcatt tggtatgggt ataaataaaa gcaatgtccg ttttgttatc
    32761 cattatcaaa ttcctggctc tctagaagca tactatcagg aagctggtcg ggcgggaaga
    32821 gatggtcttt ccagtgaagc catcctgctt ttctctcctc aagatatcca agtccaaaag
    32881 ttttttatcc agcagtccca aagagaagaa gggcaaaagc aaaaagaata tgaaaaatta
    32941 aaagcgatga cagaatacgt gtatattgag tcctgtcttc agcaatacat cctaaactat
    33001 tttggcgaga caagcagtcc gtgcaaccgt tgtggtaact gtttagatga cagagaaata
    33061 gtagaagtaa cgacagaagc acagatggtt ctttcttgct taaaacgtat gggtgagaac
    33121 tatggtaaac aaatgctgat gaaagtctta gcaggatcga aagaacaaaa gctgcaagct
    33181 ttaggttttg gacatttatc tacctatgga ctgatgaaaa accaatcgca aaaagaaacg
    33241 atgcagttaa ttgaatattt gatatcgaat ggctatcttc tgaccatcaa tggtgagtat
    33301 cctgttttga aagtaacaga aagagggata caagtattga aaggacaaga atctgtttat
    33361 cgaaaggaac ccaagaaagt ccagcagcta tcggatgaag aaaccgatac actatttgaa
    33421 gtgctgcggg aactgcgaac ggatctagca tcagaagcag gcgttccccc gtatgtcgta
    33481 ttttcagatt ccacattgaa agaaatgagc cgaatacgtc catcaagcag attggagatg
    33541 cttcagataa aaggagttgg ccaaagcaag cttgataaat atggcgaagc ctttttatct
    33601 cggataaaaa atgcggactc taacgttctg gataagtaga aagaacgaat acgtaaaaat
    33661 gaataaaaac aactggttaa atctgttttt tttgctcctt atgaaaatca aatatgttat
    33721 aattaaggaa ttagaatggg aggtaagcac agatggattc tttgtcgaaa aaacttgcga
    33781 tccaagtatt aaatgatgaa gcagaacgga tcaaacgatt aatccgaaat caaaacaaca
    33841 gtctctgtat ctcacaatgc aaagccttcg aagaagtggt agatacacag atgtacggct
    33901 tttcccggca agtcggtttt gctgtccgta taggagtaat cggaaagaac gagggccagc
    33961 tgatgttaag tgagctagaa cgagaattga atcagttata tagtgaggtt taccaagaaa
    34021 tttatgataa aaaagaagtt ggcaaggagg aatagacttg cctaagaaag tgaaaaaaag
    34081 gcatctatta gactatagca tcttgattcc ctatttaatt ttatgtgtat tgggattgat
    34141 catggtatat agttctacgt cgtatctatt attagaaaac ggacaaaatc cgtccgcatc
    34201 agtcattaac cagagtattt tttgggtgct tagcttgatt gctatcgcac tactttataa
    34261 aatgaaaaca gatgttttga aaaaccagcg tttgatcatg gcagccatcg cagttttgac
    34321 gattttgctg ctgattgttg tgttttttgg taaggagatc aatggggcga aaggttggct
    34381 gcaaattgca ggattctcga tccaacctgc cgaataccta aaaatcattt ctatctggta
    34441 cctgtctctg actttatcta aaagacaaaa cagtgtacaa aaagattttc ttgggactgt
    34501 gaaacgtcca cttgcaatgg ttatcggact tactgcatta gtcgctattc ttcccgattt
    34561 tggtaatgcg gcagttatct ttttgattat tttggttctg cttttagcca gcggagtcaa
    34621 ttatgtgtat actttgattg taggagtagg aggcttttgt ctaagtactt ttacgatctg
    34681 gctgatcaat atcacaaacg gaaagatctt acccggacgt ttacagtata tctataatcg
    34741 atttgctatt taccaaaatc ctttctcaga cgaattaaat aaagggcatc aactagtcaa
    34801 cggctactat gccatgttca acggaggact atttggcagg ggattaggta acagtatcca
    34861 gaaaaaagga tttttacaag aagcacaaac cgattttatt tatgcaatcg tagtggaaga
    34921 actgggagtg attatgggga ttttgatatt agcgttgcta ttctttatga ttgtgcgcat
    34981 tgtccttgta ggtatccgtt caaaagatcc gttcaattcg cttttgtgca ttgggatcgg
    35041 cgcaatgttt ttgatccaag tatttgtcaa tcttggagga attactggcg ttattccttt
    35101 gacagggatc acgttcccat ttttaagtca aggaggctcc agtttgctga tgctttcgat
    35161 ttgtgtcggc tttgtcctca acatcagtgc ggatgaaaaa cgcaagagct taggtttata
    35221 ataaaaaaag atgtaggagt ggttcgatga aaaaagtttt agttgctaac aggggtgaaa
    35281 tcgctgtacg tgtatttcgt gcttgtacag aattaggaat taaaactgtt ggaatctatg
    35341 cagaagaaga tgaatattcc gtacaccgtt tcaaagcgga tgaagcatat ttagtaggac
    35401 aaggaaaaaa accgattgat gcgtatctag atattgaagg gatcatttct atcgcgaaag
    35461 aatgcggagc tgacgctatt catccgggtt acggtctttt gtcggaaaac ttgaattttg
    35521 cgcaacggtg cgaagaagaa ggcatcattt ttgttggacc caaactgcat catttagata
    35581 tttttggaga taaaatcaaa gcaaaagctg cagctatcga agcggggatt gcttcgattc
    35641 caggcacaga tggaccaatc gcttctatag acgatgcctt ggagtttgcg aaacaatacg
    35701 gttatccgat tatgatcaag gcagctctag gcggcggcgg acgcggcatg cgtgtagctc
    35761 acgatgaaaa gagtgcaaga gagggctacg aacgtgcgaa aagcgaagca aaagcagcct
    35821 ttggtagtga tgaagtgtat gttgaaaaat acatcgctaa tcctaagcat atcgaagtac
    35881 agattctcgg ggatacgcat ggaaacgtca tccatctttt tgaaagagat tgttctgttc
    35941 agcgccgtca ccaaaaagta gtagaagtag cgccttgtgt ctctatgaat gaacagcaac
    36001 gtcaaaaaat ctgccaggca gctgtccaat tgatgaaata tgtcgggtat gtcaacgcag
    36061 gtacagtaga atttcttgtt gaaggagatg atttttactt tatcgaagtc aaccctcgcg
    36121 tccaagtgga acatacgatc acagaaatga ttacagatat tgatatcgta acaacgcaac
    36181 tgttgattgc tcaaggtttg gatctgcata aagaaatcgg attgcctcag caagaaggaa
    36241 ttaaattaaa tggttcagcc attcaatgcc gaatcactac agaagacccg ttgaataact
    36301 ttttaccaga cacagggaaa atcgatacgt atcgttcacc tggtggtttt ggcgtacgtc
    36361 tggatgtcgg aaatgcttac gcgggctatg tagtgacacc gtattttgat tcattgctag
    36421 taaaagtatg tacgcatggt gctacctttg aaacagccat tcagaaaatg gaacgttgct
    36481 tgaaagaatt tagaatccgt ggagtgaaaa caaacattcc atttatgctc aatgtcatca
    36541 cacatcctga attccaatca ggaaatgcaa aaacaacctt cattgatagt acagcaacat
    36601 tatttgaatt tcctcgacta cgagaccgcg gaaacaaaac gatgaaatat atcggtgaaa
    36661 ttactgtgaa tggttttcca ggtatcgaaa gtggcgaaaa accattttat gaagaaccac
    36721 gtatgcctaa agatctaatc acaagaactg attacgtaac ggctaagaat gtattagatg
    36781 cgaagggtgc cgatgctttg gtcgaatgga tcaaaggaca ggaaaatttg ttgttgacgg
    36841 atacgacatt tagagacgcc catcaaagtc tgctagcaac tcgtgttcgg acaaaggatt
    36901 tcaagcagat tgcacgtttg actggagaag gtcttcctga actcttttca agtgagatgt
    36961 gggggggagc aacatttgat gtggcttacc gctttttgaa tgaagatcct tggcaacggt
    37021 tgagaaaaat tcgttcttta atgcctaata cgttgctgca aatgcttttc agaggttcaa
    37081 atgccgttgg gtattctaat tatcctgaca atgtattggt ggaatttgtc aaagaagcag
    37141 cagcgcaagg aatcgatgta tttcgaatct ttgatagttt gaactggact ccacaaatgg
    37201 aaaaaagtat ccaagctgta cgggatactg gtaaaatcgc agaggcagct atttgctata
    37261 ctggcgatat caacgatcca agtcgggcaa aatacaatgt tcagtattat aaagacatgg
    37321 caaaggaact agaacaactg ggtgcgcata tcattgcaat caaagatatg gctgggctgc
    37381 ttaaaccgca ggcagcttat cgtttgatta gtgaattgaa agaaacgaca gatctgccaa
    37441 tccatctgca tactcatgat accagcggga atggaatcat cacttattct gctgcttcaa
    37501 aagcaggagt agacatcgtt gacgtggcaa tgagtgcaat gagtgggaat actagtcagc
    37561 ctagcatgag cagcttgtat tatgcactgg tcaatggtcc acggctgcca gaaatcacga
    37621 ttgaaaatgc acagaaatta aaccattatt gggaagatgt gcgcatgtat tacaaaccgt
    37681 ttgaaaacgg cttgaatgct cctgaaacag aagtatatat gcatgaaatg ccaggaggac
    37741 agtattcgaa tctacagcaa caggcaaaag ctgtcggatt aggtcatcgc tgggatgaaa
    37801 tcaaacaaat gtatcatact gtcaacttga tgtttggcga tatcgttaaa gtaactccat
    37861 catctaaagt agttggagat atggcactat ttatggtcca aaatgatctt acagaagaag
    37921 atatttatga aaaaggcgaa acactaagtt tccctgaatc tgttgtgact ttcttccaag
    37981 gagaactagg gcaacccgtt ggcggatttc ctaaaaaatt gcaaaagatt attcttaaag
    38041 gcagacctgc attgaatgaa cgtccaggtc ttttggctga atcagtcgac ttcaacgaag
    38101 taaaaaaaga attggcagaa aaaattggct atgaaccaaa acaagacgaa gtattaagct
    38161 atttgatgta tccgcaagtc tttttggact atcaaaaagc atataatcaa tttggcgatg
    38221 ttacattact ggacacacca acatttttcc aaggtatacg tttgggtgaa acaatcaatg
    38281 tacaaatcga acgcggaaaa acgcttatca ttcgtttaga tgaaatcgga gaacccgata
    38341 tcgaagggaa tcgcgtactg ttcttcaatt tgaatggaca aagacgtgaa atcactatca
    38401 aagataattc gatcatcagt acggtccaaa cccgattgaa agctgaaccg acaaaccgag
    38461 aacaaattgg agcaacgatg tctggttctg ttttggatgt attagtgaaa aaaggcgata
    38521 acgttaaaaa aggtgatacg ttgatgatta ctgaagcgat gaaaatggaa acggccatcg
    38581 aagcacgttt tgacggagaa gtcgcacatg tatatgtgtc ttcaggagac actatttcgt
    38641 ctggtgacct tttgattgaa gtgactgaga aataataagc gaaaggtggg gaaacatgaa
    38701 aagactgggt ttgttttggc tgattctgct attagttatt gtggcattct acatggaacc
    38761 agtcttgttt ccgccaaaac ttgaagtgaa ggaaaactct gatcaacaaa tatcaaacca
    38821 aatgacaacg tggaaatacc aggagcttaa agcaactggt ttttctactt atatcggaaa
    38881 accgatcgat cagctggaaa aggattttgg ccaagcctat gatcgattaa ctagcggatt
    38941 tggttttgaa acaagatatt atgaaaataa agctagtcat ctcacatttg aagcgaacat
    39001 ccaagacagc agagtcacaa ctgttaaagt actgcaaaca gggcctgctg atatcgcgcc
    39061 gttttattta gggatgacga tgcaagatct tacgaaaatc actactatct atactaattt
    39121 cacttttgag taccatgata cagaagttgg aatcgaacta atggaagagg atatgaatta
    39181 tcgtccgcta attgcttttg ataacgacac ttttgctatt ttattttttg atcaaacaac
    39241 aaacggccta ttttcagttg tgtatttaga taaagatagt cttttgaaac tattgccata
    39301 tcaagtgttt ggtgaaggcc ttccacatta tcaagcagat aaatcggctg attgggaatc
    39361 aatcaatcgc gttaaagaac gaaaaagtac gactttatta aatatgctta gaagagaaga
    39421 cgaacttccc atatacaatc aaacacttgc ctttcaaaac cacagtcagc tgctactaca
    39481 tgattttttg acaaggcctg aggaaatatt gtcagaggaa cgtatggctg attggcaaaa
    39541 atcgctaggc agtgctcaaa cgacagtgaa attctcactg acgaatgatg aattggagaa
    39601 gttaatcagt aaacaaaaat tagaaaatac tagtgggcta tttattcatc cggcgattga
    39661 cgctactttt tcgtttttat attggtacag cgatccttac aaccatgacc gtttcatgga
    39721 cccgggaacg gattctgtag gcattgcttt ttctaaagaa aatatgttag tcttattgca
    39781 agaagaaaac ggagaaagta gtgatagcag tgatcgttaa cgaagagctg tttcaactgg
    39841 aggatcaatg cctccaagtc gctgaaatga taaaaaagag taaaacgatg gcttcttatc
    39901 ttgaacataa acagtcaatg gaagaatctg caaaagtttg ccagttgaaa gaagcgttct
    39961 tgtctaagaa agaagcattt gaaaatgtag cggcatatgg tgagtatgca cctgattatc
    40021 gtgaaaaaaa acgagctgtt cgaaaagcaa aaagacagct tgatatggat gagcatgttg
    40081 cagctttccg atatagtgaa acacagctgc aaagtctgtt ggatcaaatt gtccaagtac
    40141 ttgccgaaga agtttctaat gaaatcaaag tagatgcagg tagcccgttt tttgaaacga
    40201 aaaaacactt tggatgcgga ggtaattgtc atgcaattag acaatagtga atttgaaata
    40261 acaaaacgac gcgggctgat cgtatgggtc tacagcttaa aacaattaaa gaatctgaaa
    40321 aagttcggct tgttgcatta tgtctcaaga agaatgaaat atgtcgtgct ttacttaaat
    40381 gaagagacat tggaagaaac agaagaacga atccgtaaat tacattttgt tcgaaacgta
    40441 gaacgttctt accgaccgga tatcgaaatg aattttgccg aaaaaatagg aaacaaaaca
    40501 gtattaaaag acgaaggttt cgaaattgaa gagctaaata cagaaatccg attagctgaa
    40561 catctttaaa aatctcttat gagcagtttt taaataaaaa ataacttgga taacgatcga
    40621 tttttgatca ttgtccaagt atttttttgg tatactagta ccagtaccat ttctaaggag
    40681 tgagtagatg cggataatat caggaaatta tggcgggcgc cgtttaaaaa gtttagcagg
    40741 ggcgaacacc agaccaacta cagataaagt aaaagaatcc atattcaata tgattggacc
    40801 atattttgat ggagagacag tattggatct gtttgcagga agcggtggtt tagctatcga
    40861 agcagtatct agaggctgca gtcatgcggt atgcgtagac aaaaattacc aagcgctaaa
    40921 aatcatcaaa gaaaacatcg aaattacgaa agaaccagag aaatttacca caataaaact
    40981 tgatgcggac aaagcaatcg aacggctagc agcggagaaa caacaattcg actacttgtt
    41041 tcttgatccg ccatatgcaa aacaaaaaat aatcgatcaa atccataaaa tggaagaact
    41101 gggacttttt tctaaaaccg cagttatcgt atgcgaaacg gataaaacag tcgaattgcc
    41161 agaaactgtg gctggattcc atcaaataag aaaacagatt tatggcataa cggccgtaac
    41221 tatctataga aaagagggaa atcaatgaaa cgtgcattat tcccaggaag ttttgatcct
    41281 tttacaaaag gtcacttaga tacggtggaa cgtgcggcta aattattcga tgaggtagta
    41341 attggtgttt ttatcaatac ttcaaagaaa agtttgtttc ccccagaaga aagaatgaca
    41401 ttgatcacaa aagctgtttc tcatcttcct aatgtaaaag tcatgcatca agaaaatcaa
    41461 ttgacggtag aaacagcaaa agagattggt gcagatgcgt tgatcagagg catacgaagt
    41521 atcaaagact ttgaatatga acgagagatt gctcagatga atcatcatct atatgatgaa
    41581 ttggaaactg tcttcttatt agcaaaacca gaatatagtc acgtgagttc cagtatttta
    41641 aaagaagtac tgcactttgg cggagatgtg agcagctact taccgccagt gatcaacgaa
    41701 gctttagctg gaaagcgtga atcaaatgaa agctaaacaa tggttgaaaa cagtactgat
    41761 tatcatattt ggaatgttga tcattggatt tgtagtagtt cccttgccgt attatgtaga
    41821 atcaccggga gccacgatcg atctgaaaga actaattacg gtcaatgata aggaagataa
    41881 aggttctggg tctttctctc ttacctctgt tggtatcagg caagctacag gtttcttagc
    41941 tttaaaagct aaaatgaccc cttttgaaga attgatcagt gaagaagaat tgactggtgg
    42001 ggcgacaaat gaagaatata atcaaatgca acagtattat atggattctt cccaaaatgc
    42061 agcaatcgaa caagcgttaa aacttgcaga caagccttat aaaatggaat tcaaaggcgt
    42121 atatgtcatg agtgtagaga aaacatcgaa tttctttggc aagctttcag ttggagatac
    42181 agtaacaaaa gtagacggga aaagctttca aagtacagaa gcatttatgg attatgtaaa
    42241 aagccaaaaa gttggacaaa caatcgaaat cagttatttg cataatggtg aagaaaaaac
    42301 agcttctggt gatctgatcg agttaccaac agataaaaag gcaggaatag gtatcacgct
    42361 tactgaccat accgagatcg aatcagatac agatgttcgt attaattctg gctctatcgg
    42421 tgggccatca gcgggattga tgttcacttt agaaatctat gaacaagtca ctggtaaaaa
    42481 cttgcgacat ggtaagcaaa ttgcaggaac tggaacgatc aacagtgaag gagaagttgg
    42541 ccgaatcgga ggaatcgata aaaaagtggc aagtgcggat aaagctggcg tagagatttt
    42601 ctttgcacca gatgatacga tttcagacga tgttaagaaa gaatatcctg aaataaaaac
    42661 caactacgaa gaagcaaaag ctgccgctaa aaaattgaat tcctcaatga aaatcgtacc
    42721 agtaaaaaca gtacaagaag cgcttgacta tctagagaaa atgaaatgaa actaaataat
    42781 taaagagggg ttgtgacacg a
//
LOCUS       DADVXM010000016        37866 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.017, whole genome shotgun sequence.
ACCESSION   DADVXM010000016 DADVXM010000000
VERSION     DADVXM010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.017"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            321..641
                     /locus_tag="KB927_000948"
     CDS             321..641
                     /locus_tag="KB927_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBB6839882.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            795..1700
                     /locus_tag="KB927_000949"
     CDS             795..1700
                     /locus_tag="KB927_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6839883.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            1697..2470
                     /locus_tag="KB927_000950"
     CDS             1697..2470
                     /locus_tag="KB927_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6839884.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2651..4075)
                     /locus_tag="KB927_000951"
     CDS             complement(2651..4075)
                     /locus_tag="KB927_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6839885.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            4286..4732
                     /gene="nrdI"
                     /locus_tag="KB927_000952"
     CDS             4286..4732
                     /gene="nrdI"
                     /locus_tag="KB927_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBB6839886.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(4797..6779)
                     /locus_tag="KB927_000953"
     CDS             complement(4797..6779)
                     /locus_tag="KB927_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6839887.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSAATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(6793..7689)
                     /gene="murQ"
                     /locus_tag="KB927_000954"
     CDS             complement(6793..7689)
                     /gene="murQ"
                     /locus_tag="KB927_000954"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBB6839888.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(7692..8753)
                     /locus_tag="KB927_000955"
     CDS             complement(7692..8753)
                     /locus_tag="KB927_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6839889.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(8964..9530)
                     /locus_tag="KB927_000956"
     CDS             complement(8964..9530)
                     /locus_tag="KB927_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6839890.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(9558..11060)
                     /gene="eat(A)"
                     /locus_tag="KB927_000957"
     CDS             complement(9558..11060)
                     /gene="eat(A)"
                     /locus_tag="KB927_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBB6839891.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKSQPKHLSISYVRQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(11318..12439)
                     /locus_tag="KB927_000958"
     CDS             complement(11318..12439)
                     /locus_tag="KB927_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6839892.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPHGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            12564..13505
                     /locus_tag="KB927_000959"
     CDS             12564..13505
                     /locus_tag="KB927_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBB6839893.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFRSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKTAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(13655..14551)
                     /locus_tag="KB927_000960"
     CDS             complement(13655..14551)
                     /locus_tag="KB927_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBB6839894.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFNMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLAYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPIPSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            14820..16160
                     /locus_tag="KB927_000961"
     CDS             14820..16160
                     /locus_tag="KB927_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6839895.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            16378..16821
                     /locus_tag="KB927_000962"
     CDS             16378..16821
                     /locus_tag="KB927_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBB6839896.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(17086..18504)
                     /gene="nhaC"
                     /locus_tag="KB927_000963"
     CDS             complement(17086..18504)
                     /gene="nhaC"
                     /locus_tag="KB927_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBB6839897.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(18907..20130)
                     /locus_tag="KB927_000964"
     CDS             complement(18907..20130)
                     /locus_tag="KB927_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBB6839898.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVEQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(20161..21000)
                     /locus_tag="KB927_000965"
     CDS             complement(20161..21000)
                     /locus_tag="KB927_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBB6839899.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETTVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDEKNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(21017..21697)
                     /locus_tag="KB927_000966"
     CDS             complement(21017..21697)
                     /locus_tag="KB927_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6839900.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(21699..22772)
                     /locus_tag="KB927_000967"
     CDS             complement(21699..22772)
                     /locus_tag="KB927_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6839901.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IIEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKINILQKNELDSRIKVIEGGR"
     misc_binding    complement(22828..23066)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(23108..23341)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23418..24089)
                     /locus_tag="KB927_000968"
     CDS             complement(23418..24089)
                     /locus_tag="KB927_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6839902.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYFDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(24176..26854)
                     /gene="mgtA"
                     /locus_tag="KB927_000969"
     CDS             complement(24176..26854)
                     /gene="mgtA"
                     /locus_tag="KB927_000969"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBB6839903.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLTFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASMFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGKFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNVTFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIHRFQELL"
     gene            27513..27950
                     /gene="ndk"
                     /locus_tag="KB927_000970"
     CDS             27513..27950
                     /gene="ndk"
                     /locus_tag="KB927_000970"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBB6839904.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAVDAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(27972..28838)
                     /locus_tag="KB927_000971"
     CDS             complement(27972..28838)
                     /locus_tag="KB927_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6839905.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICSKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLSLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEKKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(28998..31091)
                     /locus_tag="KB927_000972"
     CDS             complement(28998..31091)
                     /locus_tag="KB927_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6839906.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWMKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVLYWLDIATFIGILVWLTIKKIPIKSQPVSKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFSESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSAIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWNEFDN
                     AQMQRVPLMIHIPGYTKGSVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSPQHD
                     QVVAFRNGNFVTPKYTILGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKSALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNIAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKDNQ"
     gene            complement(31567..32190)
                     /locus_tag="KB927_000973"
     CDS             complement(31567..32190)
                     /locus_tag="KB927_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839907.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(32349..33746)
                     /locus_tag="KB927_000974"
     CDS             complement(32349..33746)
                     /locus_tag="KB927_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6839908.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHPEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIKF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(33778..34749)
                     /locus_tag="KB927_000975"
     CDS             complement(33778..34749)
                     /locus_tag="KB927_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6839909.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKELLEKGVTAIFVSNYNMSIGAIECFNQEGIRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGEQAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            35123..35548
                     /locus_tag="KB927_000976"
     CDS             35123..35548
                     /locus_tag="KB927_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839910.1"
                     /translation="MKKLIVLFILSAGLLTLTGCNLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQETDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATITFTKIGNYRLKDEDGNIYSL"
     gene            complement(36036..36737)
                     /locus_tag="KB927_000977"
     CDS             complement(36036..36737)
                     /locus_tag="KB927_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6839911.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(36753..37193)
                     /locus_tag="KB927_000978"
     CDS             complement(36753..37193)
                     /locus_tag="KB927_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBB6839912.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(37193..37768)
                     /locus_tag="KB927_000979"
     CDS             complement(37193..37768)
                     /locus_tag="KB927_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBB6839913.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
BASE COUNT        10933 a         7888 c         6581 g        12464 t
ORIGIN      
        1 ttttttaatt tattgcccga taatatatag aaataaggtc tagttactgt tttttttaaa
       61 tgattaataa ataacaactt ctttctatga aattgcaaag cattcatctt cttttccgct
      121 aacgatatat ccgtcagtgc ttggtacact ttactaaaaa gtatgagatt gccgatatct
      181 ggataggtgt gctatactac agaaaaagat atacgatctg ccaccgggta ggataaagag
      241 gatgatcatt ccattaggtc ttttaaggga tgattttcct ctttttgtgt atttttttat
      301 agttaaggag gaatgtaagt atggcatgga tggaattaat catagcagga attttggaag
      361 tattctggtc aacgatgatg aaatggagtg atggtttttc taaaatcaat tattcttttt
      421 acacagtgat tggcatgatt gctagttttt actttttgtc aaaggcaatc aaaagtttgc
      481 cgatgagtct ctcttatcct atctggacag ggattggcgc agttggttcg gtcataattg
      541 gtgtggtctt gtttcatgat aagctgaatc tttccacttg gttctttgtg gggatgctac
      601 tcatcagtat cattggcatc aagattacta gcggccacta gacacttgga ataagtactg
      661 atcagaaaaa ataagccttt ttatttaata ttcaattttt ttatgaaaaa ataagaaata
      721 agtccaatga cctagcgact tctccactca tcaggtgtat gcttgtacta tctatagaaa
      781 aggagtgaat atttttgaaa agtctttcgg tccaagaatt atccaagaac tttggtcaca
      841 aacaagccct cagcgatgtc agttttagct tatcccctgg caaaatcgtt ggattagtag
      901 gtcctaatgg cgctggaaaa acaacgatca tgaaagctat tttaggactg atccattact
      961 cagatggaac aatctgtatt ggtgaaaatg agatttctcc ctctagtcat aaagggttgg
     1021 aacaagtagg agcattgatc gaatacccgg gtatctatcc attcttaaca ggctatgatc
     1081 atctgaagtt attctctgaa accaacgatg tatctgctat cgacactatc gtgaatcagc
     1141 tcaagatgga aaagtacatt cacaaaaaag cgaaatccta ctcgttggga atgaaacaaa
     1201 aattgggaat tgctcttgcc ttactgaacc atccgtctat cgttatttta gatgagccga
     1261 tgaacggttt ggatccacaa gcaacaagag atgtgcgaaa aatcattacc gacttggcta
     1321 ctcagggcac ctctttcttg atctccagtc acttactcag cgagcttgaa aaaatggtcg
     1381 atgagctgat cctgatcaat caaggaaaga tcatcaaaca atgtacaatg gctgaattga
     1441 accaaacagc gcaagatttc atcgttatct ctacaacaaa tgatctagct gctcgaacga
     1501 tcttgacaga agctggatat actttggaag atcctgataa aatcaagctt ttaaaagaaa
     1561 acgaagaatt attaggaacc gtgatccagc tattgtctgc acaaaatatc catgtgacag
     1621 acgtccagca tctgacgaat gatttggaat cttctctatt ggaaattctg gattcagtaa
     1681 agggggaaga agaaaaatga cattgcttgt aaaacaagaa ttatttaaat tgatcaagaa
     1741 aaagtcaact gctgttttat ctgttctatt agttgttttg ctcataggaa cagcacttct
     1801 agccaaaaaa tacacgacga tcattgatcc agttgaaatg actgctcagc tttttagtgc
     1861 cacatcttgg attgtcttta tcatgattgc agctgcaagc acgatcattt cgatggaagc
     1921 acaatatggt acattgaaaa atctccttta tcgaaagtat tctcgaggag aaatattagt
     1981 aagcaaatgg atcacattag ttatttattc tgtttattta taccttttag ctattattgt
     2041 cactgtgttg atgaaactga ttcttttccc ttcgatttcc ttcacggaga aggtttctac
     2101 tggtcaaaca ctgatccaaa gcttgttcac ttatactttg ggtagttata tcggtttatg
     2161 gctgatttta agtttagtgt tgatgattgc ttgctttatc aatagttccg gtgcatccat
     2221 ctcagcagga atcgtctttt attttgcttc gtcaatcata tctggtatcc ttattgcact
     2281 catccaaaaa tgggagtgga tcaaatggaa tccgatcagt atgttgaatc tgcaaaacca
     2341 aattggaaac gaagagatca tgaagcaatt gactcatctt tctactaatc aaatgctatt
     2401 cggtaattta gcttacatcg ttttgttctt agcattagga tatctcgtat ttaagcgaaa
     2461 aaatgtatga tgactcatca aaaaagaggc tgtgaaagag acgttcagcc ttattgccga
     2521 ttggctgtct cttaaacacc gtttattctg aaaaaggagc tgtgacaaca tttgtgtcac
     2581 agctcctttc ctagtatgtt tttgaataaa cgacaggctc acaacctctc tttatacttc
     2641 ttttatactt ctatacgtga agcatcccag tggcaaataa aaccattgca atcactccga
     2701 ccatcgtcac acctataagt aaaatcttat ctaagtggat atgttgtaca ggctcgtttt
     2761 gctccttacg tgctttgagg taaaaataaa tgcctggcaa gaaaagaaca agaacaagca
     2821 ttacttcatt aaaggctacg actagcatag cccatacttg aaaggcactt gctaaaagcc
     2881 ctactaaaaa ttggacccat tctttccgct gataagaaag tttcatttgg tacaatccta
     2941 agaaaagcca cgtgaagaaa atagctgctg taccaagtgt gtaagcaaag ttataagcac
     3001 tgtcagtgaa taataatgaa agtaaaaaga cattcgtaca taacgtcgtc aatacgatag
     3061 cataagttgg tgccccattt ttgttgagtt ttccccatgc tttaggcaaa agtccgtctt
     3121 cagccatgtt tcccattgtt tcaatcggta agatcgtcca tgagagccaa acaccaacta
     3181 aagaaatgat caaaccgccg ttgatcacga ctgctcccca tttaccaacc atcatttcaa
     3241 acacatagcc catagcaggc tgcgccttga tcgtttgcag ctgattcatc gtcattgtcc
     3301 catatggaag catggaaacc aagacgtaaa taataatcaa gccgaatatc cctagaatcg
     3361 ttgctttccc aacatctgat tgtttttttg ctcgtgaacc tacgacagag gctccttcaa
     3421 taccaacaaa tacccaaagc atcaccatga tgcaactcaa tacttgactg gaaaacggga
     3481 tcggctgtcc attcgcattc aatataatgt cgctagaaaa gttatcaatg aattgttgga
     3541 tcgaaaacgt gctgatagct actacaataa ataaaaataa tggcactaat ttacagaatg
     3601 tgacgatagc attgacgaaa ctagcatttt cgactccccg attcactagc catgcatatc
     3661 cccataaaaa gactgtactc atcacgatcg atgccagatt ttgcccacct tcaaatactg
     3721 ggaagaaata tcctaatgcg ctcatcaaca atgttgcaaa agctacgttg cctaaccagc
     3781 atgtgagcca gtaaccccaa ccgctgataa aaccagcgaa acggccaaaa ccttcttctg
     3841 cgtaactaaa gatcccgcct tttaaatctg gacgtttttt attgatatta ttgatcgaca
     3901 aggagagcat caacattgct gttcctacga gtacccaact gaaaatagct gggccgccag
     3961 ccgatccgga gatgtccgtc ataataccaa atacgccacc tccaatcgct gaaccaatta
     4021 ctaaggcagc aagtggaatt aaaccaattc cttttttctg ttgctctgta tccatgtaag
     4081 catcctccaa aataaaaccg cttttatcaa aaagtataac aaaccttttt tatttttact
     4141 taattaataa aaactttaat agaaatataa ttctaccggc ttttttctca ttatacaagc
     4201 aaagcgccta gtccctttcc aaattacacc accaaaaaac ttaaaaaaga tgctatacta
     4261 aaaggaaaga attggaggat gatccatgaa cattttatat atatcgattt caggaaatac
     4321 gcgtgccttt gccaaacatc tagcagaata tgctgaaaaa atgcatgcag aagatcctgt
     4381 caatcctgaa gttactttaa aagaaatcca tgaaaatagt gattttacga aagaaacaga
     4441 accatttttt actttcgttc ctacttattt agacggcgga aatggtttag ataacggtga
     4501 tacagaaatc ttgaccgaaa cgatgcgtga atatctggaa catgaagaca atcataaact
     4561 ttgtcttggt gtagtcggta gcggaaataa aaacttcaat aatcagtatt gtctaacagc
     4621 caaacaatat gcacaaacat ttggctttcc tttcttggca gattatgaat tacggggaac
     4681 accatctgat gtgacacgaa tttatcagat tttagcagaa aacaataaat aataaaaaag
     4741 aagaagctga aaaatagatt tcagtttctt ctttcgtttc tattgtttct atcatattaa
     4801 gctttgacat ccatcacagg tgcttttgct tttgctttac ctgttttttc caagacaaag
     4861 ttttttacac gatccatatt ggttaccaag acgatcatgg atgtttcttt gcctgctgct
     4921 ttgatcgctt ctaagtcagc ttctgctaca agcgtatcag gtgtcacttg ctgcccttct
     4981 gttactttca catcaaatgg cgtaccgcct aagtcaactg tgttgattcc catatgaagc
     5041 aagatttcta aaccatttgg cgttgtgatc ccaatagcgt gtttcgttgg gaagacagag
     5101 ctgactaccc cagtaactgg agaatagata tgtccgtttt ctggttctac aaagtagcct
     5161 tcacccatca tcttttgtgc aaaaactgga tcacttgctt tatctaaaga aacaactgtt
     5221 ccgtcagcaa ctgatgagag gatagtcaca ctttcagctg aagtttgagg tactactttt
     5281 tcaggcactt catttactgt ggctgtttca gtcgctaatt cttctttttc taaacggtct
     5341 ttaggaatac cgaagaagaa tgtagcaacg aagccaccag cataagctgc caataatcca
     5401 aggatgtagc ctaaccattt accgtcagag atcaatggga tcaaagcggc tcctgaaggt
     5461 ccaatagcga tagccccgac atttccgatc attccgatca ctgccccgcc gatacctcca
     5521 ccgatacaag cagtaataaa tgggcgtcct agaggtaatg ttactccgta aatcaatggt
     5581 tcgccgattc ctaggatccc gactggtaaa gctcctttga tcatttctgt taattcttta
     5641 tcttttttgc agcgaatcca taatgccaat gctgcaccca cttgtcctgc accagccatc
     5701 gcaagaattg gaagcaatag cgtacgacca gtttcatcaa tcatttgcac atggattgga
     5761 gtcaaaattt gatgcagtcc gaacataacc atcggcaaga ataatgtgcc tagaacgaag
     5821 ccggcaaatg ctccaccaac gccaagtacc cagttgatcc caccgaccat gccatcagaa
     5881 atgaaacctg ctaaaggcat gatgaagaaa atttcaatca gaccgatggc aatcaatgaa
     5941 agagttggtg taacgatgat atctaccgca tcaggtacta ctttatgcag ttttttctca
     6001 acgattgaca atagccaaac agcgaagatg acacctagga tcccaccttg tccagctgca
     6061 agagcttcac cagtaaataa gtttttcagt ggtgcttccg gattcatccc tgtcagcatc
     6121 acaacggccc cgataactcc accaagagtt ggtgttgcac caaaaacttg tgcagcattg
     6181 atacctgtat agataactag gtagctaaac atcccgtttt tcaagatgtt catcacatcg
     6241 atatattgtt gccatgttgc tgcatcaagt gttccggctg tgactaagtt tgctaaaact
     6301 gcggcaatcc ctgccacgat cccagtaccg acaaatgcag gaatcattgg cacaaagata
     6361 ttagaaatgt cttttaatac cgatttgatt ttagatggtt tttgtttcga tttttgtgcc
     6421 gctttcattt cttgtgcccg ttcgtttaca cggtcttttc cagatgctga tgaatttgct
     6481 gtagctgcac ttacagaaga aagtttttct cctaatttca cgcctgccaa atcaaccatt
     6541 tgctgtgcta ctttgttcac tttcccaggt ccgatgatga cttgaagctg ttcatcttct
     6601 actacaccaa gcactcctgg aatcgctttt aattcagaga catttacaag atcatcattg
     6661 atgatcttca tacgcacacg agtcatgcag tggacaatgc tttctacatt gcccatgccg
     6721 cctgcccctt tataaatttg ttttgccagt tcttccaaag tcagttcgtt ttttgccatg
     6781 gtcttttccc cctcataagg tcccttttac aaatccgttt gcttcagcta attttgcttg
     6841 agcttcctct ttatcactat ttgtcaaaat catgacgata gccagcttaa cattttgatc
     6901 tgcttcttca aagtactttt cagctgtttc gtaatcagct tctgtcgctt gcatgatgat
     6961 tcgttttgag cgttcgatta gtttttcatt tgttggtttg acatcgacca tcaagttatt
     7021 gaatacttta cctataccaa tcatactgat agtagaaatc atattcaaga taagtttttg
     7081 tgctgttcct gacttcaatc gagtagagcc tgtcaaaaat tctggacctg catcgacttc
     7141 gattgggaaa tccgcgtgtt tactgatttc ggcttgttta ttgcaagaaa tcgttcctgt
     7201 gacagcaccg atcgattttg cgtaatctaa tccaccgatc acatatggtg tacgaccgct
     7261 agctgcgata ccaataacta tatcattttt tgtcaaattc agcttgatta gatcttcttg
     7321 ccctagctca taagaatctt cggccccttc gacagctaca gtcattgctt cttctccacc
     7381 agcaattaga cctatgacca tttccggttc tacaccgaat gtcggtacgc attcagcagc
     7441 atctaacaca cctagtcttc cacttgttcc ggctcccata taaatcagac gtccaccttt
     7501 tttaaaggac tcaatcgtgt tagcaatcac tggttcgata cttgtcagtt ctttttcaac
     7561 cgcagcggcc actttctgat cttctttgtt cattagttga acggcttgag aaatactcat
     7621 ctcatctaat ccaaaagttt cttggtttct gcgttccgtt gttaggttct ctaaattgat
     7681 tttgctcaat tttatcttcc ttcttttctt ataaattgat agttcatacc agctttgatt
     7741 tggttgatca atggtagctc ttctttgata actttagcta ctacattcac tttttcatcc
     7801 gctggcaaat catatttggt taattggatc tcacccatat agcgcaaata cttttcgtta
     7861 tctaaagtaa tagacccttt catacgcgta gctgtatttc ttgctgggat aggcggaatc
     7921 tctcgaaaac gtgcatctgc gcttcgtatg acatctcttg catcgtcttg ccgattcgta
     7981 tgcttcccta atatatattc gtaaaattct tcatctacag gttccgtatg gagcaagact
     8041 gtctgttctt tttggaaaga agcaaattgc tcctgaacgt tttctgacag acctgcatct
     8101 ccgatgtaaa caatatccgt gttacttgct aatagatcta gagcgcctgc aagaggatgg
     8161 atccctcgat gttcttccaa agttggcaat ccttgatata gtgggcctct caactctgta
     8221 tctcctggta caaaaccttg gacaaggaga ccttgaattt tgagccattg attttttttc
     8281 tgataccatt ctttgtccag ccctgtttcg ggacgtggat aataattatg ccaagcttca
     8341 atctgtgaga aatcagcttc tgcttctttc aattcatcga tatctttagg cgtgatcgtg
     8401 ctagcattca aactgatttt caattgatgt gaccagtcgg caatctgctg attggaaata
     8461 tgataatcca ttcttaaacc tgttacacca attgctttca aaggcgttag atcttctaat
     8521 gaaaaacccg ctcgttccaa tgcctctcct gaaatatcga ccatcaattc tagtttattc
     8581 tttttcgctt cgcttcctag ttcgatcaat cgcttttgat atgccgaaac atcatcttct
     8641 ggtatatgca tggaagtgaa aataccgaca aagccattgg atgccatttg gcggatatac
     8701 tgtttcttct cttctgacaa agaatcgttc ataaatattg aaaagccaaa catattatcc
     8761 ctctttttct gtatccgtct tcatttctat gactagagta tatatctaaa gaaacaaaat
     8821 ttcaatactt ttattaaaat aattaaattt catttctaaa ggttgagttt atattatcaa
     8881 aagaattgtc ataacctaaa aaaggcactg ctaagcaaaa gcagtgcctt gaaatatttt
     8941 atttaaataa cacaaaaaca taattactca taagaaacca attctgtatt atctaccatg
     9001 aatgtaaaga acccctcatt aggcatcgga tgaaaataag cattgatcac tcttatcaag
     9061 gcattatggc aaactaacag atagacattt tcttcgtctt cgatgcattc tttcaataaa
     9121 ggaacgatcc gtgcatacac atctaagact gactccccat ttgggaatcg tacagcgaac
     9181 gctaaacgtg ctttttgaaa gttctcatct ttgcttggca gtccatcata atccccaaaa
     9241 tccatttcta ccaatcgttc atcaacggtc agcggcaagc tgagacgatc agcaactgct
     9301 tgtgctgtat ctcttgctcg ttgaagaggg gaatggatga ttttcgtgat tggaacaggc
     9361 aaatctacta ccttttctgc tagtttctgt gcctgcatct gtcctttttc agtcagcggc
     9421 acatctgccc gtccgcaaac taatccttgt gcgttccaag ttgtttctcc gtgtctcgtt
     9481 acataaagca tgtgattctc tccttcgttg gcaaagttcc ccttaaccat accttgttgt
     9541 tcttgagatt acaagggtta gattctctca agagaaataa tctcagtaga tactttatcc
     9601 aggaaggttt gatcatgttc cactagtaac atggcaggtt tcacgttcaa gatcagttgt
     9661 tctaattgtt cttgattgaa gacatccaaa taattcaatg gttcatccca tgtatatagt
     9721 tcagctggct gtgataaaga tttagccaat tccacttttt tccgttggcc catactcatc
     9781 tgctcgatct tgttatgaaa aacatctctt tccatcccaa gctttcggag gttgttcaaa
     9841 aatgcttggt agtctacttg gtttttctct gcaaattccg ccaacgttcc tcgattgtct
     9901 tcataatttt ggcgtacata actaatgctc agatgttttg gctgggattt ttctcctata
     9961 accttgccgt tgaatgcccc cagaagataa tggataatgg atgactttcc tgcaccgtta
    10021 ggacctgaaa tcgccacccg ctgatgaggc tcgattgtaa aatgaattgg ctcgaataac
    10081 agattttcat accctaattg aagatcttct acgcttaaaa gtcgcttatg gtgagacgct
    10141 tggctattca tcgtcaaaga atcgatatat tcgatatctt ttaatagttt ttctttctcg
    10201 ctgatctggg tctccatccg attcacgatt gctttggatc gtttcatcgt ccgtgcagca
    10261 tcagcaccca ctgctccttt attcactcgt ctagattcag tatcgatgaa tccgacttgt
    10321 ttctttgttt tatctccttc tcgggaacga gaccattcgg ctttttcagc tgctgttttc
    10381 tttagcctac tgacttcttt tttcaatttt tcattttgag ccatttcaaa ttcatcacga
    10441 agttttttct gttcttcata gatagagaaa ttcccttgat aaagttccag ttgacttttt
    10501 tcgattgcta aaacatggtc cactacttca tcgataaatc cccggtcatg gctgaccacg
    10561 atgaagcctt gttttttctt tttcaaataa gccgctactt gttttctacc agagatatcc
    10621 aaatgattcg ttggttcatc gattaacggg aaatgagtgt catccacaaa taaaagtgcc
    10681 agtaggactt ttgtcttctc tccccccgat agtgtgctga attctctcca taagatttca
    10741 ggatctgttt gcatcaattg gagctctctt tcgatttccc atatctcaaa atccgtaata
    10801 tcatttaaca cgtaataggt taaacgttct ttatcttttg tctgttgcgg gaaataggca
    10861 aattcttgct gatggattac ttgcccttga taaggtagtt tgttttgtag aatattcagt
    10921 aaagttgtct ttcctcgacc gtttcgtccg ataagtccta gtttccattg tgtgtcaaaa
    10981 tttagatttg cttgttcaaa taataatgtg ccttggctgt cgtagccgaa tgtcagattt
    11041 tttatttcga ttttagacat tttccatcac ctcgtaaaaa aagaccagtc ctattttcag
    11101 aactggctaa agaggatgca agggttggat acacacaaaa agacccatac atcgaaaaaa
    11161 ccaagccaat cccgaaaatc tgcacactgc ttccttgtct ccacaaggta cagtctgaat
    11221 gcagctttca tcaatcgact taatttttca atgcacggat ccctcacttt gtcctatatt
    11281 tgaaattacg atagcataaa gaaaatgatt ttgtcaacta cttcgggagg atggtgaaaa
    11341 atctgctaag tgtctgtcct aagatttttg ttttttctaa tgtttgcctg tgttccattg
    11401 cttcttctaa acctattgga cccaaatgaa tacttaagac aattgggaga aaatcagaga
    11461 gtccttctag ctcttggtct ctacttccgc aaatagcgat tattggtttt cgatattttt
    11521 ttgcaagcac tgctacaccg tgtggaactt ttccgtggat cgtttgctga tcgatccgcc
    11581 cttctcctgt aatgatgaca tctgcttgtt cgatcttttt ttccaatcca gtgatttggc
    11641 tgactaaatc gaaaccagaa accatcttcg ctcccaacaa aaaaagggct ccaccaatac
    11701 cgcctgctgc tccacttcct ggaatatcat ctaaatccac ctcccagaaa tcttttattt
    11761 gctgagcaat ctttcctgct tgtttatcta agaaagctag cgtcgtatct attcctcctt
    11821 tttgtcttcc aaattgccaa gcagctcctt gttgacctgt atatggattg gtaacatctg
    11881 cagcgataat caattttact ttagaaacaa gaacgtttct tcgatcaaaa tgaagttttt
    11941 tagtagataa taaaggattt ccttctgtgt acccttctaa agaagcaccc aaggattgga
    12001 gtaatcctag accaccatcg ctacacccgc ttcctcctaa agtgacaata atttgttcta
    12061 cttcttgaag cagtgcatct ttgataagtt ctcctaaggc ataactggaa gcaagtcgga
    12121 tagtttgatc cgttggttta tcaagtagat ctaaccccaa tgcttgtgca gattcgatga
    12181 ctgcggtatt ttttccttgc caagttgtca ataaatagct gatttttcgc tgacggaata
    12241 aaagatccat cccatcaatg gtgcgccatg ttcccccgag cgcgtaatag attgcttctg
    12301 cagtattttc tccgccatct gcaatcggca cattgatttt tcttccttta cgatcttccc
    12361 agccatttag aactgcctga tttagttcaa atgaagaagc acttccttta aatgaatcaa
    12421 ttgccgccaa aatatccatc tgtatccctc actttcttct taagtaagac actttttttc
    12481 atttttttca aacaaaacaa tgctattttc ttccattttt ctatatacta aaagggaact
    12541 cattgataaa ggagagaaaa aacatgaaaa tcgcaatagc tggagccgga gcaatgggca
    12601 gccgaatcgg attgatgcta catcaaagcg gaaatgaggt cctcttgatc gatcgttggc
    12661 ctgcacacat tgaagccatt cgtacaaatg ggttgattgc tgactttaac ggtaaagaag
    12721 tggtcgcaaa actgccaatc tattcaccag aagaaatcat cgaaagcaac gaacacgtgg
    12781 acttgatcgt agcattaaca aaagcgaatc aattagatga tatgtttcgt tcgatccaat
    12841 ccattattac tgacaatact tatgttttgt gtttactaaa tggattaggt catgaagatg
    12901 tactggaaaa atatgtgcca aagaaaaata tcttatttgg gatcacgatg tggacagctg
    12961 gtctagctgg tcccggaaaa gtcacattgt taggtgatgg agaaatcgaa ctagagaact
    13021 tggaaccaga aggcgaagca tttacaaaaa aagttgtgga agtctttcaa gaagcaaaat
    13081 taaatccgat ctatagccat aatgttcgtt attccatttg gcgaaaagct tgtgtaaatg
    13141 gaacattgaa tggtttatgc acgattttgg attgtaatat tgctgaacta ggcgcgcaaa
    13201 aaacggcaga gagcatggtt cgaacaatcg tatctgaatt tgcttctatc gcagcaaaag
    13261 aaggaatcat attagatcaa gaagaagtgt accaacatat tgcttctact tatgatcctg
    13321 acaacatcgg gttgcattac ccatctatgt accaagacct gatcaaaaac catcgtttga
    13381 ctgaaatcga ctacatcaat ggtgccgttt ggcgaaaagg acaaaaatat gatattgcta
    13441 caccatattg tgcctttttg acccaattag tccatgcaaa agaaggaatc cttggcgcag
    13501 aataaaaggc tctctgatga gaatcagctg aatcagcagc tggttctctt tttttaagcc
    13561 caatgaaaga tcaaaaagaa aacacaactc tcatgatgcc ataagaattg tgcttgtttg
    13621 tttcggtaca taatctcttc aaaatgtagg ttttttattt attttcaaca gaggagaggt
    13681 catattcgta ttgctcataa atagtggaat cgttagtgat aaatcgtttt gcccaatttt
    13741 ctgcatcata aaattccaat agctctgatg ggattggctt aaaaggtgta tgcagaaatt
    13801 ccggtaattc atctaaatca cgttctcgaa gcaaaaaaat attttcagga cgataaaaat
    13861 gataatgagc aatcgcttga ttatccgtca ctagtttctt ttgaaaatac atagattcaa
    13921 atgtccgcaa agtcactcct tgctgaccct cccgcaacag ttccagaatc ccgcgcgatt
    13981 cccctgtttt tttcaggtac tcttcataag caagatatcc aggttgttca ttccctcgat
    14041 gtggaagaat gaaatagttg gtcgtaacat ctctttttat aaattcctgc ttatagcttt
    14101 ctgctcgttc ttttctccca ttattcgttg caccaaaaaa tagatccgtc tttggttcgc
    14161 tagaagaaaa atccatatgt ttcgaataaa atgaactatt atgtttcagc ccaagttctt
    14221 ttgcttccaa aaaatcaaaa tgataaatct catcgattgc cggttcatct tgtgcctgct
    14281 tcagcatcgc ctcgtgttct gctttgaagt gattccaaaa aaataacaca atttttgcat
    14341 tggtaaatgg gcgcacgcgt cgagccatct ccatattaaa tccataatct aaaaaaacga
    14401 tcagctgata atttgccaac tgttgtctag ctgatttaat gaattccgac tgtagtaaat
    14461 cttttccgga ccaaacatct aaagagcgga tggaaggcaa aaaataaagt gatttatttt
    14521 ttgcaactag cagtacgtca tttttgttca tcttttccgc ctcactttct ctgtcacttt
    14581 ttcctatgat agcctgttta aatagtaaaa agccagtaaa acgcttccta tatttgtatg
    14641 aaaatttaac atttgtatga aaatatgatg aaataaatca ttcttctatt aaaattcgcc
    14701 taaaagtttt ctgaatagtt gtaattgtct gaaaatttgt tatcattagt cattgttaaa
    14761 tattgctatt tattcttaat ataaattttg attgtgaatt taaaagaaag aggtcattta
    14821 tggaagataa aaaattgaaa aaacaactta gctccagaca tatcaccatg ttagctttag
    14881 gtggagcaat cggtgcaggt ctatttaaag gaagtggcga agcgattggg atcgccggcc
    14941 cttctgtatt gattgctttt ttgattggcg ggctgatttt atatatcgtg atgaaaggtc
    15001 tgggaaaaat cgttttaagc ggtggcgaca cgcatcacgg attatctggt ttgatacgcc
    15061 cttatctagg tgctcattct gctgatttta ctgattgggt ctactggtct atgtggatta
    15121 tcaatatcat cgctgaagct gttgcagctg cttccttttt gcagttgtgg ttcccgcaca
    15181 ttccagcctg ggtatttgtt tttatgttgg ctgttttaac tacgatcatc aatctttatt
    15241 cggtacggtt attcgcagaa acagaatatt ggctggcttt tgctaaaatc agtgtcatta
    15301 tcttactaat catttttgct acttatcttg tcggtcagca aatgttgggc acaggcgttt
    15361 tccctaccct tcagcaattg actgaccatg gtgggtttac tcctcatggt atgaagggaa
    15421 tcatcagttc tttgcttgta gttatctatt cttacggcgg ttctgaactg attgctatca
    15481 cggtaagcga agcagatgat cctaaacgtg cgattcctaa agccatcaaa ggtgtcatgg
    15541 gaagaatcat ttccttttac atcattcctt tgtttttgct tttgattctt tttccttgga
    15601 atactttagc aggcacgaat gtcagtcctt ttgtgatggt atttgaaaaa atgaatatcc
    15661 catttgcagc ggatatcgtc aattttgtta ttgtccttgc tttgttctca tctatcaatt
    15721 cgggtgtgta tgcatcttca agaattttgt tcttccgttt gaaggatcga aaaggttcct
    15781 ctagaaaact agctgtttta aacaagcatc aagtaccgca acgtgctgtt ttattttgta
    15841 ccagtgttct ttatcttggt gtagctcttt cttattttgt cggtgacaaa ttatttggct
    15901 atctggcagg ttccctttcg tatacagtat tattgatctg gatcattatc agtgcggcat
    15961 cctttgtact ggcactaaga aaaggaacat tatgggataa aggaatcagc ttttttgcat
    16021 tagctgtctt aggattgatt ttccttggta tcctgttcac gaactccatt ggggtaactg
    16081 tattgactgg cctgctttac ctgttcattt atttcagtta tcaaaaaaag aatgatgcgt
    16141 tcgtattgac gaatgaatga aatcgataga aaattttatt ttatttatgt ggaatagatg
    16201 gaactattga agaaaggagt tgtgacaaaa gtcttgttgc aactcctttt tccgaataaa
    16261 cagtctcatg acctcttggt aaacggtgtt caaaaaccct ctgtgcaaaa taattgattg
    16321 ttctccatgc tcatgacatg atagaagaaa ggaatgaaaa aaaggagttt gttttaaatg
    16381 aaaaagtatt ggaagttttt gttgatgatc ggtgtttcaa cggtagttat gtttggtatg
    16441 atgtacttga atgtctatgc gctcgatcat atcttcttca gtcgtacacg agtattcatg
    16501 gcgttgatga tgggtgcagt catggcagtc atcatgctgt tgttcatgtg gaaaatgtat
    16561 gaaaacaaaa agataaatgt tatgatctta gccgctagtc ttcttgtttt tgccggttcc
    16621 ttgtttatgg tacgaagcca aactactgtc aacgacacag cttggatgaa ggccatgatt
    16681 cctcatcatt ctatcgctat cctgacaagt aaacgagctg atttaaaaga tcctgaagta
    16741 aaaaaattag cggaagaaat catccaggca caagaagaag agatcgacaa aatgaaaaaa
    16801 atgatcaaag aaatggaatg accattatcc gtccaaataa aaaaagagga tgttccagaa
    16861 gtgatcagct tcaagaaata agaagaagct acttctggaa caccgtgaat aaggggttgt
    16921 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagct tctcctattt
    16981 ttcgtttggt taggcttatt accgcagatg caagcttttg aacaccgttt attcgtaaaa
    17041 gggattgtga caaaaaaagt cttgtcacaa tcccttttta tgtttttatt gttctaattg
    17101 cgctgtcttg cttactgctt cttgcggttt cacaaatttt tttgagattc cccaacctgt
    17161 gaaggcactg accatcgaaa acacaggaga aagcaaactg aaaaatacga atggcaagta
    17221 agtgagtgta ggaataccaa atgtacttgc tacgaaactt ccggcaattc cccaaggcac
    17281 taagtagttg attactgttc caccatcttc tagcgttcta cctaatacag ttggatcaaa
    17341 tcctgctttt tcataagttt ctttaaatgc attaccaggc agaataacag ataggaattg
    17401 ttcaccaata aaaatattta ctccgatact tgtcatcaat gttgtaaaaa tcaattttgg
    17461 tgtgttcgtc atctttcttg atactcgttc catcacggtt gagatcaagc caaattcgat
    17521 caacaatcca cctaatgaca aagttagaat aatcaatgac acagtaggca tcatactttc
    17581 gattcctccg cgactaagca gtgaatcgat ttgttggttt ccagtatttg aaacaaaccc
    17641 tgattcgatg accccagcca acttcgttaa ggaagtttgt gggttttgaa taaaaatcat
    17701 tcctactgct acagcgatat tcaacaaaat cgtcaaaatt gccggcacct ttttccatgc
    17761 acacagtaac attaaaaata aaggaatcag tgaccagatt gaaatagtaa agtttgcttc
    17821 tagaacatca gtcacttcac gaatagatga aagacttgcg gctttacttg tgtgccctaa
    17881 aatcatgaat aaaaagaaag aaacaacaaa tgccggaaca gttgaccaca tcatatgctt
    17941 gatgtgtttg aacaaatcgg catcaacaat agctgctgct agatttgttg attcggataa
    18001 tggagacatc ttatctccaa aaacggcacc tgaaacaata gctccaacaa ccagcgctgg
    18061 atttaggcct agtgttgtcc caataccgaa aaatgcaatc ccaatcgttg acataacagt
    18121 aaaggcactc cctacagcgc tacctacgat tgcacacaca acaaatacag aagggacaaa
    18181 ccactggaca ctgatcaatt tgaacccaat gaccattaga gttggaatga tccctgcttg
    18241 tatccataca gcaatcaatg aacctactaa aataaaaata aagattggga tgattcctgg
    18301 tttgatgcca ttgatgattc cttcgtgcag ccaatctgtc gggtatcttt ttatcactgc
    18361 atacaacatg accattccga tcgctgctaa gatcgtgata ttaggtgaga cctttaatcc
    18421 gacaacgcca atcgcaatgc ctaaaacaat aaccattaat acaagtgttg cttctaaaaa
    18481 acttggtgtt cctttttttc ccatgataat ctctcctttt ttagttgttc ttatgttcta
    18541 aaaaagttaa gatatcggat tactccgccg caattcatcc gctattcctc ctttataaaa
    18601 ataaaaagac ctgttttaaa ctaaggacga atgactccgc ggtaccacct taattaaaaa
    18661 cagatctgtt tttcactttc aaacttttat tcaaatgtat ggactttcca tgtaattcgt
    18721 caattaggct tgatcggttc acagcgacca ccgactttct gaacaaaaca cctaaccgct
    18781 actgcgtgaa aagttgactt gtatgaagtt taccttccat aagatcattt gtcaatgaaa
    18841 aagaaaatat tttttcattt ttctgaaaat tatttttata actttcacac acaagtttat
    18901 tttttactag aaagtagcac cctcttgttt ttttcttgct actatttctt gatgttcttg
    18961 cttgattctt tctaatagct ttggctcttt caacagatca agagctgtat tggcgagtag
    19021 ttctgctgca atcgcaatag aagcaaggcc tttgtcactt ttagcagcag ctttgaattc
    19081 ttctgtgtgt ccggcaatat atgtctcaga gattgctacc gtaggctgga ttgttggtat
    19141 gacttggctg acatttccta catcagaaga accgagactt gttctttgtt ccgtttctat
    19201 ttcttcatct ggaacacctg cttcttttgc atgctggaag aataagtcat caaaagaagg
    19261 agtaacgatg acatcatcaa ctgcattttg gaacaatcca aactcaaaag tcgtgcccgt
    19321 acttatcgca gcacctcgta cgatattttc cactttttca tatactttat ctaatgtttg
    19381 ccgatttcct gcacgtaaat agaaacgtcc agcagcgtaa tctggaatga cgttggcagc
    19441 tactcctccg tctgtaatga tcccatggat attgacatct tttggcaatt gcaagcgtag
    19501 agcgttgatt ccattaaaca cttggatcaa tgcttccaaa gcatttactc ctttttcagg
    19561 tgctgctgct gcatgggaag cgacaccgta aaatttgatg tcgactggat cattcgctaa
    19621 agattctgtc gttttcccat aacgaaaagc tggatggacg cataacgcta catcgacatc
    19681 ctcaaaaaaa ccttctcgaa caaagctgcc tttagctgat ccgttctcgc ccccttcttc
    19741 ccctggggtg ccatatacac ggatttctcc accagtttca tcaataaatt gctccactat
    19801 gctggcggct aatacggagt aagtaccaaa caaattatgc ccgcatgcat gaccaatacc
    19861 tggtaaagca tcgaattctg ccaaaaaggc aattgtgggt ccgggtttat tggaaatata
    19921 acgtgcatca aaggctgttc ggtgtccagc tacttctttt tctacccaaa acccttcttt
    19981 ttctaattgt ttaatcaacg ctgctgagga ataaaactca tagttactta cttcaggatg
    20041 ttcgtggata tctagagcaa gtgcttgata ttctggtaaa cgatattgga ttagatcctt
    20101 caattggttt gttgagattg ttgttgtcat aaaaaattcc tcctatgcta gtcatttttc
    20161 ttattttctc ccgaatgttt cccatgcagg cacgcttgat ccttttgatg ttttctcgat
    20221 tactttgact gtgtcttctg tttgataagc gtctactatt ttttgatacg ttttattttt
    20281 ttcatcttct tttcttgcaa cgatgatatt cacataagga cgtgcatggt catccactgg
    20341 ttctaagaag atggcatcag aagcaggatt aaatccagca tctacagcta caccgctatt
    20401 gatcactgaa atgtctacat ctgacaaagc acgtgctgtt tgggaagcat ctaattcaga
    20461 aatgtctaga ttttttctat tctcggtaat atcagaaaca gtgggcgctt gtccttttgc
    20521 cttatccact ttgatcaatc cagcagtttg caataacaga agagctctgc cgccatttgt
    20581 aacatcatta gggattgcta cttttgctcc gtctttgata tcagctacat ccttcaaagt
    20641 gttagaataa attcccagcg gtgcattgac agtatttccg atcgatacta aatcagttcc
    20701 gtgttcttta ttgtaattgt ctaaaaagaa ttgatgttgg aaagaattca aatcaatcga
    20761 tccatctgct aaagccgcat ttggttgatt gtaatctgta aatttcacgt attccaaatt
    20821 aatgttctcc tttttcaaac ggtctttcac gttgtcccat acatctgtat cttctccaat
    20881 aattcctagt tttacggtag tttctttttt gtcagttgta tctgcttttc cttggctaca
    20941 ccctgccaac caaataattg ctacaaatgt aatgactaca aaacgaataa tttttttcat
    21001 tttttctcct ccactttcaa tgtgtaattt ttttaatcag ttgattactg ataaattgac
    21061 ttaaaaaaac taagattaga atcaataatg tagccacaat cgttacatct gtttggaatc
    21121 gattataccc tctcgatata gcaagattcc ctaatccgcc tgcacctact gctccagcca
    21181 tggtagtcag tccgatcacg ttgatgatag tcaacgccga gacccgaatg ataccaggca
    21241 aaccttctaa caaatacaca cgtaaaataa taccgattgg actggttccc atcgcttctg
    21301 ccgcttcgat caccccagga tcaacttcta gcagtgcgtt ctcgatttga cgagcaaaaa
    21361 acggaacaac tccaaaaatc aatggcacta aagctgcttt cgcaccaatc gtcgttccaa
    21421 ctaagaaacg agtagtcaat gctaaaagag aaagcaagat aatgaaaggg atggaacgaa
    21481 tgatattgat cagcttatca agtatttcaa atagcagacg gttagctagt aatccattag
    21541 ggcgtgtcac tactaacgtc acacctaaga tgattccgat catcccgcca atgaatgctg
    21601 tccaaaaaga catatatagt gtttgcttcg tcgcttcgac aaattcatcc ggaatcaaat
    21661 aaacattggg caaatatgtt ttaaagaaat cagtcatttt atcttcctcc ttcgatcact
    21721 ttgatacgac tatctaattc gtttttttgt aaaatattta tttttacacc agatttgatc
    21781 aaataatcca atgctttttg ccgctgtttg gtttctccag ctaaagtaac gatcaaactc
    21841 cctaacggcg tttcttgtaa taactctaca ttgccatata aaatattcgc tgttacttga
    21901 tatttgctgt acagatgagc gattagaggt tcgttcgtct gatttccaat ataacttaat
    21961 tccaccagcc atttattggc gatctgatcg gcaaaagcag aatgggcaat gatcgtttct
    22021 aatgcttggt caagatgagt agctgttcga ataaaatctt tggtcaattc ttcttcagga
    22081 ttgctgaaga tctggatgct actacctttt tcaatgattc ttccatcttc cataaccgct
    22141 accttgttgc agatttcttt gacaacttgc atctcatgag tgatcaggac gattgttaaa
    22201 cctaactggc gattcaattt ttttaacaat gcaaggatct gaagggtcgt tttcggatca
    22261 agtgcactgg ttgcttcatc acataataat accttaggtt cattcgccaa agctcgtgcg
    22321 attgctactc gttgtttttg tccccccgac agttgtttag gataagcaga tgctttttct
    22381 tccaaaccga caagttccag tagttcattc actttttgac gacgttcctg tttcgatttt
    22441 ccagaatact ttaaagaaaa atcaacgttg tcaaaaatag ttcggctttc cattagattg
    22501 aaatgctgaa agatcatacc gatggccttt ctttcttttc gcaattcttt gggagagagc
    22561 tgactcaaat tcgtctgatt gacaatgact tctcctgctg ttggtttctg cagcaaattc
    22621 atcacacgaa ctaacgtact tttccctgca cctgagtaac cgacgattcc ataaacatcg
    22681 cctttttcaa tcgttaaatc tacagaatct actgcctgta tctctttttc tttttgtttg
    22741 aaacatacag aaacatctcg caattcaatc attaaaattc ctccttatct aaaaaaagcg
    22801 tcctcaagaa aatgaaaatg tcattttctt gaggacgctt ttttgcgtgt taccacctca
    22861 tgttcaagct gtgttcacac acaactcctc ttcaagtacg atcatactct agcaagatat
    22921 cggtcgcagc cgtcatcgcc ttacatctat gctcgggatg aattgctcga tggccatttt
    22981 ccaatagtcg ttccttgctt cttctcagct accgaagctc tctgtcaaag gttcttctat
    23041 cgtacttacc atttcaatgc aaataatatt caaaaaaaaa tccttttact aacataaact
    23101 atgtcagtaa aaggacgacg tatcgcggta ccaccttttt tcggaagttt ccttccctca
    23161 agcccaacat ctcaaaaaga gagattggcg ttcgttttaa cggtcgaaca gttccgaatt
    23221 tgcctactta tcgacaaatt attctccaag gccattttca gcttttctta cttgactctt
    23281 ctcaccagcc agagcctctc tgcaaagttt ccaaacttac tttccttttc aacgaaatcg
    23341 atattttgtt gttgggatta atctacatga ggaaaactaa aaagtcaagc acgaaattca
    23401 aattattttt tctatattta tttttctgtt tttttatcta acatttcaat aacagttcga
    23461 agatcttttc cttcagcaag aagtttcaat ttttcctttt cttcgacggt ataatttcgg
    23521 acaaaactgg aatcaggtat caaaacaacg cctaatcctg ctcgtgaagc agctgttgct
    23581 cctactaaag aatcttccac tgcaaaggct gaactagctt ctaatcctgt tcgttccaaa
    23641 gctgtcagat aaggaatcgg tgaaggcttg ttctccgaca cttcgtctcc gaatgtaaac
    23701 gtgtcaaagt aatcagctaa tttaaagtga tccaagatat ctgttgctct tttcgtaaca
    23761 gtggtcgtag caatgcctag tttcatatga cgttctttta agtctgccaa tatttctttt
    23821 gcatatggtt ttaagtggat ggctccgctt gtcagctgtt gataaaaata ttcttcacgc
    23881 ttcgctcgga cttcctgtac tttttcaggg ctacctgctg ctttcactaa aatatcaaaa
    23941 ctttgtttcc agttttttcc gccccaagcg tcaacgattt cttttgggat atggatatca
    24001 aattgctgaa atccccaaag ccagccatca cgatacgttt tttctgtgtc aactaacaaa
    24061 ccatctaaat caaatattgc acctttcatc tatacattaa tcctttccaa aacaatacac
    24121 atagtttagc acgactggtc caaaaataac agaagcaaag aaccagcctt ctcgtttata
    24181 agagttcttg gaatcgatgg atatagattt tcttcacagc tgtcacaagc gccagataag
    24241 cgatgactgt agcaaataac cataaccagt aattgccagg aagtggcatc aagcctaatt
    24301 cagcaccaaa acttgtaaaa ggaaggacag aaccgacaat aattcctaat gtagtgataa
    24361 caaacatggc aaatgttacg ttgctttgga taaatggtac tttcggtgta cgcagtgcat
    24421 ggagcactaa ggtttgtgtc catagtgatt cgacaaacca tcctgcatgg aataatgcga
    24481 tgaaaatcac ttgctgtgaa ctatccaatg tatggaaact tccgccaact acagcaggac
    24541 aaataacaaa atacatcaac aagtaagtag taatatcaaa tatcgaactt gttgggccaa
    24601 agtaaaccat gaatttccca atactagatg cattccattt ttttggctcg tccaaatatt
    24661 ctttatccat ccgatcccat ggcaaggaaa tgcaggaaac atcatagatt agattcaaaa
    24721 acagaagttg taaaggcagc attggtaaaa atggcaggaa catacttgca atcagcacgg
    24781 aaaacatatt gccaaaatta gaacttgctg tagccttgat atatttcatg atattcccaa
    24841 aagtttctcg tccagaaaga aggcctcttt ccaaaatcgt caaatctttt tctaaaagga
    24901 tcacgtctgc agattctttc gcaatatcca cagctgtatc tacagaaata ccgatatcag
    24961 ccactttcat tgcaggagcg tcattgatac catctcctaa aaatccgaca gtatgaccat
    25021 ttttacgtaa agctgtcgtc aaacgtgctt tttgctgagg attcaatttt acgaatactt
    25081 catggtcttc agctacttgt gctaattcat gatcactcat ttccgagatt ttctcaccgg
    25141 taaccaattc attgatctct agacctactt gacggcacac tgaacgtgta actaattcgt
    25201 tgtccccagt cagaactttt acagctacac catgttcttt cagagctttc aacgcttgtt
    25261 tcgttgtttc ttttggtgga tcaaggaaag taagataacc aatcaaaacc atgtctgact
    25321 catctttgac tgaaaattct ccaacgacgc ttggattggt cttttgtgcg acaccaatca
    25381 ctcgtaagcc atcttcatta agtgactgta cttttgcaag tacggcttct tttcgttctt
    25441 ttgttaatgg tgtaacagta ccgccaagat caataaattt agaaatgttc agcatttctt
    25501 caatcgcgcc ttttgtgatc atttgtgttt taccagctgg atcagcaacc acaacactca
    25561 tacgacgacg ttcaaaatca aaaggaattt catccacttt ttgataattg atcttatctg
    25621 tatctaaagt ttctgttgct tcatcaatga tagccacatc taacaaattt ttcagccctg
    25681 tttgatagta gctatttaga tacgcatggc gcaaaacacg atcatcttca tttccttcac
    25741 aatccatatg atattcaaga atgattttat cttgtgtcaa tgtccccgtt ttatccgtgc
    25801 ataacacatc gattgcacca aagttttgga tggcattcaa atttttgatc actgttcctt
    25861 ttttggccat cacacttgct cctttgacca aattcgtcgt aacgatcatt ggaagcattt
    25921 caggtgttag accaactgct acagatagtc caaaaagaaa agcttctagc caatcccctt
    25981 ttgtaagccc attgatgacg ataactgctg gagccatcaa tgacataaat ttgatcagta
    26041 gcatggatgt tttatggatg cctaattcaa agcttgattg aattggtttt tcagatagcg
    26101 tttctgctac atgaccaaat agtgtttcat ttccaacaga aacaatgatt ccttccgcac
    26161 ttccacttat gacattactt cccataaaga caagattttc gtaacttgtt tcgctttgct
    26221 gatcgtcttc acatactttc gcatgctttt ctactggata gctttcccct gtcaatgctg
    26281 cttgggaaat gaataaatcc tttgcggaca ataaacgcat atccgctggt atcatatccc
    26341 ctgctgaaag ccgaacaaga tctccacaga cgatttcttc cataggaatc tctgtgtact
    26401 ttccattacg ttttacagct gccgttactt tcacaagtga tttcagtttt tcagccgctt
    26461 gattggaacg tacggactga atcaacgtca ttgtcccgct gacgatgacc atagtgaaga
    26521 taatggctac accgaaaaga tctttatctc caggagctgc taatacatat tccgtgatga
    26581 atgaaataat tcctaatgcg atcaacacta atgtaaatgg cgtgatgtat gctttcaata
    26641 tttctacgat gaatggtgtt tttttgccat atgaaatcgc attttcaccg taattttctc
    26701 ttgaacgttc gatttgttct tctgtcaatc catttgctga tgcgtggaat agttcaaata
    26761 attcttgttt cgtttttcca gcaaaagctg catagatttt ttgtgtatct ttcttttttt
    26821 ccatctcaat ctctcctttg tgtccaaaag acagctgttc tcgctgcttt tggtctttag
    26881 ctattcatcg gatcgataga gaaaaaactg aaaggggctg agaacagata gataatagcc
    26941 ttggcctttc ctctagatcc ttgtttttcg aatgactgtc atccatttgt tctcatctcc
    27001 tttactaagt aattttaatt catgacttcc aatcattttt cgaatagtta ttttcccaat
    27061 tagaccacct cctttttatt tttcaccgat ggggatttgc ggcaacaaaa aaacctctcg
    27121 ccaaatactc agcgaaaggt ttgaaaaagc atattaaaaa aagcttctca gatctcatcg
    27181 ttgagttttg acactgtaca acgtaaaaag cagatacctg cttttagcta ccttatgaaa
    27241 agccttatct cgacaattcc tgttctaccc attggcgtct ctcgacgttt ttgggcagta
    27301 gcctatgttt gtataggagc ctcacctaac aaatcttatt cggttttcct tcgttaatat
    27361 aacaactaaa aaagaggatg tcaaatcaat tttccatgtt tttcatactt tttttaaaat
    27421 acacacgtta tattcctgtc tcacgcggtt ttatttgtct cattttccac ctcccgctat
    27481 aatagaaata tagtaggaaa cgaggtgctg ttatggaaag aacacttgtt attatcaagc
    27541 cagacggcgt gagacgccat ttagtcggaa gcatcattca acgttttgaa gcaaagggac
    27601 tggccattgc tgaaatgaag tttgaaacta tgactcctga attagcaaaa gaacattatc
    27661 agcacttgac tgagcgcagt ttttttgatg aactgatcga ttacatgact tccggtcctg
    27721 tcgtttatct tgtgctggtc ggcgaggaag tgatcgatat cgtccgtaag atggttgggg
    27781 caacaaaagc tgtcgatgct gttccaggta cgatccgagg agactacgcg ctgccgggga
    27841 ctgaaaacat cattcacgct tctgattccc gtgatgctgc ggtaaaagag atcgcccgct
    27901 ttttcccgcc attcgatata aacaaaccgt ctgaaaaagc ggcgaagtga tacaaattct
    27961 aaactgctgg tctagttgct gggttcagca atggccagca gttttttctc taaggacctc
    28021 cgttgattct ttcctaacat atattcgagc actgtgaaga attcttggta gtctttcgtc
    28081 tttttttccc ctaaagcagc agaaatcaat ctttgataat aatctgccat caatgtttca
    28141 tagatcactg tacttctttc tttatgtgct aagctccgtt tcatatcttc attcacacta
    28201 cgtgcctttt tcaaccgacc attttctata taaaacgaag tcaggttcat taaaaaagta
    28261 aagagatact gctcatgatt gttcaactgt gctaatcgtc gcattctttt tttgattttc
    28321 aaataattgt tctcaatgaa ccgatcactg aatatccaag gaaaatcagc tagaatagat
    28381 agttcaaatt gaccatagtc tggtatctgc atcaagtatt cttcaatgat tcggcattca
    28441 taacgtaaaa attcaaattc tgtctcagat acttctgttt tttcgaccat gtgaagactc
    28501 aaaaccaaat aatacagatc ttctgttttc ttaaaatgcc tacggttatt gctgatctct
    28561 ttataaggat caaagctgtc ttcttgtacc cgatctagca ttcgtctttt tttctttaac
    28621 tttattggtt catccagctg gtttcgcatc cattcatatt ctgcaagtgt catgttcatt
    28681 cgctctaaaa atgatctcaa tgttacaaat gacatttttt tcactgaatt tgtctcaatc
    28741 ccgactagag aagtcttaga acagattcct tccgctaatt gggactgtgt caacttcttg
    28801 ttgactcgaa gtttcttgat caattcacca tcatacataa tagttctcct ttttaattta
    28861 aatttttcca cattcaataa atagatacgt taaaaaggaa aaatacacga aaaaaataaa
    28921 aaaatgtttt tttcataaaa aataccaacc ttcaagcatt agaatgttgt ctaactactg
    28981 aaggttggtt tgattgttta ttgattatct ttttgctgtt caacgtctgt tcttgttact
    29041 ggatataagt tggttgttgt tttattgcca ttttttgaaa agacacttgt cgaatgttcg
    29101 cctttttgct tttcgatggc tatgttacgt tctgcttcat ttttatagtc atattttttc
    29161 ggatcgatcg tttcaaatcc gtttggcaca taaaaacgca agagattttc ttgattcagc
    29221 ttatctgaaa gacttaaagc agatttgact ttttcctgat ctttggaaat ttcctcgtcg
    29281 attcctgctg ctttcgtatc gatgatttct cctgtttggt tattgtaagc ttttcctcct
    29341 aagatggtgt atttgggtgt cacgaagttc ccatttcgaa aagccactac ttgatcatgc
    29401 tgaggagata ataaatccgt accaaaatgg agatagtctt tatcatcgat tcccaagaga
    29461 tgaagtaatg tcggcaaaac atcgatttct ccaccgtatt cgtgattgac tgacccttta
    29521 gtataaccag gtatatgaat cattaatggc acacgctgca tttgtgcgtt gtcaaattca
    29581 ttccatgtat ctgggtcttt tccaagagca cttgctaagt ctttattatc tgtatttgag
    29641 atgccaaaat gatccccata aatcacaaag atcgaatttt ggtaaatagc ggattttttc
    29701 aggtacgtaa aaaattgttc caatgactga tccaaataat gtgccgttcg aacatagtta
    29761 tctactgtgc tatttccagt gttcaaagat ggaaaatcga aattcttatc atccgtataa
    29821 taaggcgtgt gattggttac ggaaaggaat ttcgtgtaga acggctgttg tagatgttca
    29881 agatattggg cagattcact gaataaatct ttatctaata ttccataacc tagcgtttca
    29941 tctgattcat caaaataaga tcgatcaaag aaattgtcat aacctaagtt tttatataca
    30001 tgatctctat tccaaaaact agctacattc ccatggaaaa cagcgcttgt atagccttgc
    30061 ttttgtccaa ggatcgctgg tgcggcttga aagacattat ctgacccaag ttctgtgaat
    30121 aatgagcctt gaggtaaacc aaatgtgcca gtttccaaca tattttcagc atcacttgtc
    30181 tttccctgtc ctacttcatg aaaaaaatta tcaaagctga tcgttgcttg attctggaaa
    30241 atactattta aaaacggtgt gacttcttgt ccgtctacct tcatattaat caaaaactgc
    30301 tggaaacttt ctaaatggag aacgatcaca tttttccctt tagcgatccc aaatgtttcg
    30361 ggatttggct ctgcataatg tttctttgta taatctaaaa cttcatcaat cccattactg
    30421 cttgcatgcg cgcgaacact gctagtcatt cctgttttga ttccatcata aatagtatac
    30481 gcatcgattc ctagatattt gacaatatat gaacggtcaa atgttcgctg cagcaattgt
    30541 ggacggttgg cttcgctcag cgctagattt cctgaaaaaa taagccctga aagacaggtc
    30601 acagcgatag ccatcggttt gctgacaggt tgacttttga taggtatttt cttgatcgtc
    30661 aaccaaacca gtatcccaat gaacgtagca atatccagcc agtagaggac atcatggggt
    30721 ttcatcaaag aaaaggagct tcctgataac ccttgcgaca ctttcgaaaa tcccaataca
    30781 gatttgactg taatgaaatc tgtgaattcc cgataaaaaa taatgttcaa gtacaacaaa
    30841 agcgtgttta aaatatcaat gatcaaaaga atggctaatg ctggctttgg ctttttaata
    30901 tacaaagaaa ggccaaaaaa caataaggta gttgcaatcg ggttgatcca caagataaag
    30961 tactggatcg taccttccac acctaacgaa aaatctgcat agtaagcaat aatcgtcttc
    31021 atccagaaaa agaaaacagc tgtcaaaacg attgctaaac gattttggca caatttttta
    31081 agttgtgtca cgtatatcac ttctctctat tcacattttt ccttattttg ctcctgaaaa
    31141 atgaaaattc cctaaaaaag ttgttatctt aagatttttt tattctttct aaagattatt
    31201 ccgtgcactt ttcacagcat aaaaccgctg tgatataagc gattgaaaca gtaaggtgat
    31261 aaaagtcttg tcgcagctcc tgtttagttg atgcaggaca gctttttcac aacttcttct
    31321 ttaaacggtg ttctcctgcc aactcctcgg ccacaagtca caatatttat aaaacatgag
    31381 aagctgtttt ttgaaattgt tccttgtggc tcagagttaa acggcaagct caagacctct
    31441 tgatacacgg tgttcaatca gctgaccttc ggtattagct caaaaaacgg caaaatatga
    31501 ggaactattt tgccgtttgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc
    31561 tgtttttcat tgtccatagg attgatattg tccttgtgat gactcattcg taataattga
    31621 ggcttgattt tcttcacttc ccgttatcgt ttgtccactg ccagaatctg aaggacttgt
    31681 tcctgtcgac tcgttttttt gagaagagac agttgttttc ttgacttgtt catttgtctt
    31741 tttccattcc gctaaacgat cggcgaccac ttttttgtct actttttcag aataagcggt
    31801 gatcactttt ccatttttca aacgggctac tttgtcgcca tcatgagtca aaagcaaaac
    31861 ggtcaaatgc ttgtctttaa attgatattg tctgagagaa atcgcactaa gtacgtcatc
    31921 gatattaata aattgatttt cttcttttcc ttttggcaaa tagatgtcca attcgccttt
    31981 ttcgtaattg gcagttattt tatactccgc ccaccaataa gttgagaatt cttttttgaa
    32041 attatctact gattctttgc ttgctacgat tttttctgtt tctttctgag caagatctgc
    32101 tgtcattttt cctgaaaatg ctgcggataa aataagcagt aagaaaaaac cgaataacca
    32161 aaagagaaga aacggtcttt ttttcctcat gctttcctcc actcctattt aattttgact
    32221 attctattat atacaaaaaa tgaaatagaa agacaaaaaa gttgaaaaag atcgtaaata
    32281 attgaacttc tttttcacaa aatggtaaga atggagaatt tcacgcattt gctctcaact
    32341 attctttctt aagcctcaaa tccgttttta tctgatacgt ctttgaacca gtgacccgat
    32401 tttttgattg ttctttttcc atcttgtgct aagtctactg aaataaagcc atatcgattc
    32461 ttatatgcat tggtccatga ccagttatcc atacatgtcc acatatgata gcctaaacaa
    32521 ttggcacctt cttgaattgc ttgatggaca tatttcagat gagattggac aaatttgatc
    32581 cgataatcat cgtggatcat gccatcttct ttgataaatc gtgcttcgtt ttctacaccc
    32641 ataccgtttt cagaaataaa gcagtcgata tttccataat gatctcgtac attgatcaaa
    32701 atatcataga ttccttgttc atagatctcc catccgcgat aaggattcat tttacgacca
    32761 ggcatttcat aattgtcgaa ataatcctca ggcattggac cgtttttagt atcgattggt
    32821 gtttcttttg cttttacccg gcgtggctgg taataattga tacctaaaag atctactgta
    32881 ttttctttga tgaccgtcaa atcctctgga tggatcacag gcatgagatc aagttctttt
    32941 actatctcaa tcaattcact tggaaactcg ccttttacag ctggatcaag gaatgaacga
    33001 ttgaagaacg catctgctat ttgcgctgct ttaacatctt cagggtttga ttcgtctctt
    33061 ggatagcttg gtgtcagatt caagatgata ccaataacac caccttgctc catttcatgg
    33121 taagatttga tggctaacgc tgaggccaac gcttcatgat agccaacttg gatcgctttt
    33181 ttcatatctg actcttctgg ataatgccat cgatataaat aacctgcttc gactggaacg
    33241 attggttcat tatgagtaaa ccattttttt actttcgaac cgaacaattc aaaacaactt
    33301 ttggcatatt tttcataggc ttcaaccgtt tctcggttca accatccgcc tttttcttgc
    33361 agatacatcg gcatatcgaa atgatacaga ttcacaaagg gttcgatacc gttttcaatc
    33421 aactcatcaa aataacgatg atagaaacga acggcttctt cgttgattgt tccagattca
    33481 tcaggtatca agcggctcca ttggatagat gttcgaaatg aattatgccc agtctgtttc
    33541 atcaactgta catcctcttg atacttcgta taaacttgtg aagttttttc aggtcctact
    33601 tggtcaaaga acttttgcgg ttcttttttg taccaataat caaaaatgtt ctctcctttt
    33661 ccatcacctg aaatccttcc ttctgtttgt gggccacttg ctgcagaacc ccaccaaaaa
    33721 tttgctggaa attgatattt tttcatcaaa gcacctcttt ttctttttta gttcgtttta
    33781 gttgattcca tgtatgatat tttccatcac aattactttt tcattttctt cctcttcttt
    33841 tttgattcgt ttcaacagct gttctgcggc ttgttccccg attttatctg ttggtggtgt
    33901 aatcgtgatt ttcggaagga tgctcaaatc gtttttatcc aaataatcat aatgactaaa
    33961 cgcaatatcc ttcccgattc tgataccttc ttgattgaaa cattcgatag caccgatcga
    34021 catattataa ttgctgacaa aaatcgctgt tactcctttt tctaataatt cttttgcccc
    34081 ataatagcca ctttttctag aatagtctcc tgtaaagacc tctaattgga tcgatggatc
    34141 attttgtacc gcttcttttg ctcctgctaa acgttctctt gctacgtagt ctgtttgagt
    34201 ggcagcaata aatccgattt ttttatgtcc ttgttcacca tgatgagcga tcacttttgc
    34261 tacactttct cgatcattca ctaatattgt atcaatacct gctggtcctt ctgggcaatt
    34321 caatgcgata actggaatac tcatttttgt gagcatttca aatccagacc actcttcttc
    34381 ggataagaag acaatcagcc catcgatcac atgcttcatc aggtattcaa ttttttgttc
    34441 aattttttct ggctgatcgg caaacccgct taataataag ctatacccat tttcttcagc
    34501 tactctttcg atccctgaga caacttccga cccaaaacgg ctggaaatcc cgtttatcaa
    34561 aagtccaata gagaagcttc gattattctt caacccttta gcaatgatgt tttctttata
    34621 gtccaacgct gaaatcgctt ctgctatttt tttcatgttc ttttccttca gttgctgacc
    34681 attcaagtaa cgggaaactg ttcccactga aacaccagcc atcttagcca cgtcacggat
    34741 cgatgccata cattctcact cctgccagtt acatttgatt tctctttctt gttgttcgat
    34801 tatgatgacc gctttctttg catagtgttg cttgtcatca atatccatat aactaaagtc
    34861 ttcagtagag caacttcctc tcactattaa ttatacttaa acaagtattt gaaccggttc
    34921 atttttaata tagcattttt ttaaaagatt gcaacacttt ttttaaacgc tttcctaaaa
    34981 tggcgaattt tttgcctttt taaaatttta ttctaaaatt tactctattt gtgggtgttt
    35041 tgtgcgtttt tctcttccat ccgtttgaag ttttactttc caatggtata atttctttat
    35101 cctatcaaat gggggaagta ttttgaagaa attaatcgta ctatttattt tgtctgcggg
    35161 acttttgaca ttgactggct gtaatttgtt tggcggctct gaccaatcct cggatgaaac
    35221 aaccgattct tctgtcttaa aagcggaaaa agcagatatc actaacagtg tatatacgct
    35281 aaaagtacgt aaagatatgg atttatccgc gggacagttg acatttacag ataaaaaaat
    35341 ggaatggaca cgcacgtatc agacacaaga aactgattct tctgaatcat ctgaagaaaa
    35401 aacagtgctg acagacatca agattactac caaagatgac gaatatatta tttcaggaaa
    35461 agaaaataaa aaagaagcaa ccatcacatt taccaaaatc ggtaattacc gtttgaagga
    35521 tgaggatggc aacatctaca gtctatagtg ccgtctgttg gatcttcttt tgtttctccc
    35581 cttcttttct gctatagtaa agaagcaaga tgattgtaaa ggagacgaaa tggatgatcg
    35641 atagtcctga ttattgtaca tgtaataaca acaaaaatat ccatacagaa tttaatgacc
    35701 aaggaagctt gagcatatgc gacaactgtc acaaactagt caaagattca tttaaaacat
    35761 ttgaatctta tcctgttcaa aattatgtaa aaagtagaag aagataaaca aatccaagca
    35821 aaactcacta tggctgattt ttatgaactt caaactcagc ttcttccttt gatcaagctt
    35881 catcagtaaa acaaacagtg gatcatttca gtttacaaat caaagagtaa agatttattt
    35941 atttcaaata tttgaatata aaataaccaa acgatagaaa ggcttattct acatcacgta
    36001 gtaatttttc tttcccgtcg tttggttttt tatttttagc ctaattcttg accttttgca
    36061 tgctggttat ccgtaaaata ttttccagca ggctttcctt ccaattcagc taatttttct
    36121 tggatctgac ggatcacctt ttttgcatct tctggatttt ctacaaaatc gaatttatcc
    36181 ccatccactt gtattttagg acatacatca aaatcttcat accattgatt atagcgggtg
    36241 ttcaacgttt cataataggt atataacgtc tcatcgcttt ctagctgttc atagtcacgc
    36301 ccacgttttt tgatacgttc tagcatcgtg tccaaagaaa ctttgatatg gaccatcaaa
    36361 tcaggccgtt tttttggagc aacatcatct aactcgttta gcatcgtatc taataagcta
    36421 tcgtactgct gtacttcgat atccgttacc cgacctaaat cagcgtttag atggaacaac
    36481 aggctatctt catagatgga tcggtctagc acattgtcat cgttcactaa agcatttttc
    36541 attgctaaaa atcgcttgtt caaaaagaag atttgcaata aaaaagcgta ctgctcagga
    36601 tttgaataaa agagcggcaa tacttcgtta tcttcgacat tttcataaaa tggtttagaa
    36661 tcaatctctt ttgcaagcat atccgtcaaa ctgctcttac ctgcaccaat cgttcctgaa
    36721 atcaaaatca ctgacataca acccttcctc ttctataagt actcgcctac gtaagtttca
    36781 acaggcaatg tttcaaaatc atattcacgt acagcttggt ctgattttaa atacgtatgg
    36841 agactttgtg taatcatcaa gttcgtaggt accgtctctt cttgtacaat gatcatcggt
    36901 tttttcaaca tagttgccac acctaattcg taagccgttc ctggatcgat tgtttgatgc
    36961 tcaaagtcaa ggatagcaac aacaaattct gcatttgtca gttcttccat atctttttcg
    37021 tatacttcct gcgcccatcc agcgctgaat agttcataat tgctttcttg gtgatgacgt
    37081 ggagagtaga aacttgtgac tgttttgttt tcctccaacg ctttttcgat acgacttact
    37141 cgatcgattt gctcctctga aaaaaatggt cctgctaaat atatttgact cattattttg
    37201 cctccttcaa taataactga tttttaatag atactgctcg taattcattg accagttcca
    37261 atggattgtt ggaaaagatt acttgatcca accatttttt atccataaaa tcctcttttg
    37321 caaaagtttc taataattgt tgcaagccgc tgtaataacc gccaatattc aatattccga
    37381 ttggcttgtc gggcgtcaga ccgattgcta tccaagaaag aagttgtgag aattcctcca
    37441 atgtacctag acctccaggg aaaacgagga cagcatctcc cttttcaaat aataatacct
    37501 ttctttcatc gatcgtttct gtaggaataa atgtagtaac atcttttcca ggcaattcag
    37561 tttcaaaaag cccattcgga tagatacctg tgacttttcc gttattttcc agtactgttt
    37621 tactaatcac tcccataatc ccggagtatg aaccaccgta aaccagttcg atttcttctt
    37681 gtgccatgta ttttcctaac gtttgcgcaa taaatttgta actttcttta ttaccaaaac
    37741 gggaaccgca aaaaacagta agtttcataa aaaaacactc cctaactcaa aagtctatct
    37801 tcattctaca cgtgtttttt taaaataaaa gactagattt tgtagttttt tagtggtata
    37861 taggat
//
LOCUS       DADVXM010000017        36605 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.018, whole genome shotgun sequence.
ACCESSION   DADVXM010000017 DADVXM010000000
VERSION     DADVXM010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.018"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            24..695
                     /locus_tag="KB927_000980"
     CDS             24..695
                     /locus_tag="KB927_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6839914.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            754..1194
                     /locus_tag="KB927_000981"
     CDS             754..1194
                     /locus_tag="KB927_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839915.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1206..1874
                     /locus_tag="KB927_000982"
     CDS             1206..1874
                     /locus_tag="KB927_000982"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBB6839916.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1938..2561
                     /locus_tag="KB927_000983"
     CDS             1938..2561
                     /locus_tag="KB927_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBB6839917.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2617..3003
                     /locus_tag="KB927_000984"
     CDS             2617..3003
                     /locus_tag="KB927_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBB6839918.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3216..4607
                     /locus_tag="KB927_000985"
     CDS             3216..4607
                     /locus_tag="KB927_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBB6839919.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5218..5586
                     /locus_tag="KB927_000986"
     CDS             5218..5586
                     /locus_tag="KB927_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBB6839920.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5766..6707
                     /locus_tag="KB927_000987"
     CDS             5766..6707
                     /locus_tag="KB927_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBB6839921.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6776..7507
                     /locus_tag="KB927_000988"
     CDS             6776..7507
                     /locus_tag="KB927_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBB6839922.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7651..9831
                     /locus_tag="KB927_000989"
     CDS             7651..9831
                     /locus_tag="KB927_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBB6839923.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9851..10333
                     /locus_tag="KB927_000990"
     CDS             9851..10333
                     /locus_tag="KB927_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBB6839924.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            10349..11110
                     /locus_tag="KB927_000991"
     CDS             10349..11110
                     /locus_tag="KB927_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBB6839925.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            11241..12575
                     /locus_tag="KB927_000992"
     CDS             11241..12575
                     /locus_tag="KB927_000992"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBB6839926.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12882..13367
                     /locus_tag="KB927_000993"
     CDS             12882..13367
                     /locus_tag="KB927_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBB6839927.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            13360..14043
                     /locus_tag="KB927_000994"
     CDS             13360..14043
                     /locus_tag="KB927_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBB6839928.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            14169..16814
                     /gene="polA"
                     /locus_tag="KB927_000995"
     CDS             14169..16814
                     /gene="polA"
                     /locus_tag="KB927_000995"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBB6839929.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16859..17695
                     /gene="mutM"
                     /locus_tag="KB927_000996"
     CDS             16859..17695
                     /gene="mutM"
                     /locus_tag="KB927_000996"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBB6839930.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17659..18288
                     /locus_tag="KB927_000997"
     CDS             17659..18288
                     /locus_tag="KB927_000997"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBB6839931.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            18340..18672
                     /locus_tag="KB927_000998"
     CDS             18340..18672
                     /locus_tag="KB927_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBB6839932.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18984..19475
                     /gene="nrdR"
                     /locus_tag="KB927_000999"
     CDS             18984..19475
                     /gene="nrdR"
                     /locus_tag="KB927_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBB6839933.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19498..20871
                     /locus_tag="KB927_001000"
     CDS             19498..20871
                     /locus_tag="KB927_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBB6839934.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20871..21797
                     /gene="dnaI"
                     /locus_tag="KB927_001001"
     CDS             20871..21797
                     /gene="dnaI"
                     /locus_tag="KB927_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBB6839935.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21926..22366
                     /locus_tag="KB927_001002"
     CDS             21926..22366
                     /locus_tag="KB927_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBB6839936.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22510..23211
                     /locus_tag="KB927_001003"
     CDS             22510..23211
                     /locus_tag="KB927_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBB6839937.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            23208..24329
                     /locus_tag="KB927_001004"
     CDS             23208..24329
                     /locus_tag="KB927_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBB6839938.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            24344..25576
                     /gene="pepT"
                     /locus_tag="KB927_001005"
     CDS             24344..25576
                     /gene="pepT"
                     /locus_tag="KB927_001005"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBB6839939.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25708..26616
                     /locus_tag="KB927_001006"
     CDS             25708..26616
                     /locus_tag="KB927_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBB6839940.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26651..26923
                     /locus_tag="KB927_001007"
     CDS             26651..26923
                     /locus_tag="KB927_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBB6839941.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            26934..27980
                     /locus_tag="KB927_001008"
     CDS             26934..27980
                     /locus_tag="KB927_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBB6839942.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            28231..30840
                     /gene="clpB"
                     /locus_tag="KB927_001009"
     CDS             28231..30840
                     /gene="clpB"
                     /locus_tag="KB927_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBB6839943.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(30991..31677)
                     /locus_tag="KB927_001010"
     CDS             complement(30991..31677)
                     /locus_tag="KB927_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839944.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(31655..32149)
                     /locus_tag="KB927_001011"
     CDS             complement(31655..32149)
                     /locus_tag="KB927_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBB6839945.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(32169..33389)
                     /locus_tag="KB927_001012"
     CDS             complement(32169..33389)
                     /locus_tag="KB927_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6839946.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            33536..35371
                     /gene="lepA"
                     /locus_tag="KB927_001013"
     CDS             33536..35371
                     /gene="lepA"
                     /locus_tag="KB927_001013"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBB6839947.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(35465..36592)
                     /locus_tag="KB927_001014"
     CDS             complement(35465..36592)
                     /locus_tag="KB927_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6839948.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        12185 a         6474 c         7824 g        10122 t
ORIGIN      
        1 atgatgaaaa aagggggaga aaaatgaatt ttttagttgt tttaaaagat actctgattg
       61 agcgatctac atttctatat gttcaattgc aggaaaataa aacattgctg catttttcac
      121 cagagttcca tctagagggg ctaacattag gagaaatcta tcaagcagaa gggctgtcgg
      181 ctgttttgca cttttttaag gtagaattgg aattaccagt aaaagattat atcgagcttt
      241 ctcttgaatc ttgggatcga gcagtggttg aactgtttcc agaaggttta atgatcgata
      301 caaacgatgg gaagatccat ctgactgcag cagaactgca aaaacaaatg cgttatcaaa
      361 tagatgacga aaattctttt tctattttta gacgtcagca aaagattcta aaaagctttt
      421 taaaagtgat cagtaaaaaa cggaatctga tcaaaacgac acagctgttg aaaaaatatc
      481 caggtctgct tcacacgtct attcaatttc ctcaattgat tacgatgatc catcgtttta
      541 tacgtatgca acagctacca tctaagaagc tgtttcttcc attgacggac acatttcgag
      601 tagtcaacag agaagataaa aagaaagtga ttgtgattga ctttaccaga aatcggaatg
      661 tccttcacca agttgcaatg gaaaaggcca attaaggctt tttctttttg gatttttttg
      721 tcataataaa tattagatga tggaggagat aatatgatgc aaacatggtt agaaaggcta
      781 atacgatttc agcagaacta tcacaaactt atgcagggaa gatatgcgaa atttgatcag
      841 ttgaatcgcg gtctattgat cgctgcgctt gtctttagtt tgctaagtcg ttggttgccc
      901 tatagaatcg gacaattgtt gttcatcgtc tttttcggat ggatgatatt tcgtttccta
      961 tcaaaaaaaa tctaccccag actaaatgag aatcaacgtt atttgaaata tcttgataga
     1021 gtcaaagaaa aatatcatca gataaaaaac aaaaagcaag tcaaaatgga tcgaaaaagt
     1081 tatacttttt ttgagtgccc gaattgtcat caaaagcagc gtgcacctaa aggaaaagga
     1141 cgaatacgtg tgacatgcaa aacatgtggt ataaaattcg aaacgaatgt ttaagggaga
     1201 aaagaatgaa attagtatta ttacgtcatg gcgaaagcga agcaaatttt gaaaattact
     1261 ggacaggatg gctagatgtc gccttaacag aaaaaggaaa agaacaagca gcagttgccg
     1321 gtcaaaaaat gcttgaagcc ggacttcaat tcgatgccgt ttatacctct gttttgaaac
     1381 gtgcgattct taccggacaa gtcgcactag aagaaatggg tcagttatgg cttcctataa
     1441 taaaaacatg gcgtctaaat gaacggcatt atggggatct tgtgggtaaa aacaaagata
     1501 agatgaaaga aatatacgga aaagatcaag taaaaacatg gcgcagagga tatacggaag
     1561 ttccgccgtt aaccgcagaa aatagatttg accgcagata tgatcacttg gatccgcatt
     1621 tgatcccata cggagaaagt ctggaaatga cagtgaatcg gatcattccc ttatggcaag
     1681 atcatctagc accaaaacta aaagatcggc aagatttact agttgtgggt catggtaata
     1741 gcatccgagc actgacaaaa tatttagaag atgttcctga agatcaaatg gatacgatcg
     1801 atatcccaaa tgcacaacca atccagtata cattagcaga tgatttgaca attctggaca
     1861 aaaaaatact ttaaagaaca cctttatcta aaagtgagag atagaaaaaa gaagcaaagg
     1921 aatggaacaa aaggaacatg aaaaattata tatgggactt tgatggtaca ttgtttgata
     1981 cgtatcccgc aatggtagat ggtgcatggc aagcactaaa agattttggt atcagtatgg
     2041 acaaaaaaga aatctacttc aaaatgaaaa agtattctac tagttatttg atcaatgaat
     2101 caaacttgaa tgccagagag tttaatgaat tatttcaccg atatgaaaaa gaaagtacgg
     2161 aagtttcccg tccatttcca gaaacgaaac aagtactgga aatgctaaaa gacaacggcg
     2221 gtcgtcattt catcctgacc caccgtttga cagaatcaac atggggcctg ttaaaagaac
     2281 atcgattggc acatctgatt gaggaagtag tagggatcga tcaggacttt cctcgtaaac
     2341 ctgatccagc atctttaaat tatttgatcg atacttttca tttagaaaga acagacacga
     2401 tgatgatcgg cgatcgtcgt ttagatatcg aagcagggaa aaatgcagga gtcgctactt
     2461 gtctttacga catcgatcat tttctgggtg agatcccggc agattatgtg gtaggaaatc
     2521 tgaatgaaat ccttaccttg cagagcatca ttaaaaagta gtatcccctt tcaaaggaga
     2581 tatgttataa ttttcataaa ggagtgataa aattatatgg aaatcagaag acaaaaagaa
     2641 gttgtagaag catttcatta tgatatgaga ttgccgaacc aagaagtaga aacagatttg
     2701 aaagtaggct tctcgccttt aaaagaaacg atcgaaaact atccgaaaga acatagcatc
     2761 gtaggagcac gcttagagtt ccgtttagtg tttgatacat atgttttatc tggaagtgtg
     2821 agtcagatca atcatatcct caatcggaaa attgaaggtc aaaatgatgt cacacaagaa
     2881 gaagtggacg agctagtagc accgttattc gatatcgtac gccgaatgtc ttatgaggtg
     2941 acagagatcg ccttagatca gcctggggta aaattgaatt ttcaatcaga aaaacaagaa
     3001 tagacagtaa aaacatacct gcgatagatt aaagctatca caggtatgtt tttttattac
     3061 taattgtaag caaaaagaat gtcatttcga taaaaatcgt ctaaaatata aaagtcactg
     3121 aaaaaaattt tttcaggagg atggttgaag aatcattctc gggaaccttt acttccttcg
     3181 atggacttgt cattaataat atgaggagga gaaaaatgac aacactcatc acagttttag
     3241 tggttctagt ttttgcggca ttattatatg tgttctatcg tatgcaaaag cgccatacaa
     3301 aattttcaac acgcgtcttt acagcattag gagttggtat cgtctttggc ggtctgcttc
     3361 aattgatctt tggtgtagac gacaaagtcg ttactcaatc aatggaatgg atcgggattg
     3421 taggtcaagg atatgtatca ttcttgcaaa tgctagttat gcctttagtg tttatttcga
     3481 tcattggtgc attcacaaaa atgaaagttt ctgaaaagct agggaaaatt agtgcgactg
     3541 tattgacttc tttacttgga acaacagcta ttgcagcatt gatcggaatt ggttcaacaa
     3601 tgctgttcgg actccaagga gctaaattca cacaaggagc tgcagaaaca gcacgaatct
     3661 ctgaactggc aacacgtcag gaaacagttg aaaacttatc gattccacag cagattttat
     3721 cctttatccc taaaaacgtt tttgctgatt tagcaggtag tcgtgcaaca agtacgattg
     3781 gagtcgttat tttcgcggca tttgtcggaa tcgcttatct aggcgtgaaa agaaaagcgc
     3841 caaaagaagc agcattcttt tcagatttag tcgacagtct gtataaaatc attatgcgga
     3901 tcgtgacgct tgttttgcgt ttgacacctt atggagtatt tgctttgatg acaaacgttt
     3961 tggcaacaag tgattttgca gctatcgtca atttaggtaa atttgtcgtt gcttcttacg
     4021 tagcattgct tgctgttttg attgtccact cactgatttt gattggtgca aaagtcaatc
     4081 caatcaacta tttcaaaaaa gcctttccgg tattgagctt tgcgtttact tcacgttcaa
     4141 gtgctggagc tttgccattg aatatcgaga ctcagacaaa agctttagga gtagatgatg
     4201 caacagctaa tttctcagca agttttggtt tgtctattgg acaaaacggc tgtgctggcg
     4261 tttatccagc tatgttggca acgatcgtcg caccagcagc tggagtgaat gtctttagtt
     4321 tggaatttat tttgatgctt gtggcaattg taacaatcag ttcttttggt gtagctggag
     4381 tcggtggggg cgcaacattt gcttcactga tcgttttagg ggcaatgaac ttgccagtag
     4441 caatcgttgg gttagttatc tctgttgaac cattaatcga tatggcacgt acagcagtaa
     4501 acgtcagcgg tagcatggta gctggtatcg tgacaagtgc acgcatcaaa gatttagatc
     4561 gcgatgtcat caatgatgat tctaaagtga tcgatgtgaa tgcatagtca aaaagaggtt
     4621 gtgatagaag tggtcagctt taagaaataa gaagaagttt cctaaaaata gtttctcaaa
     4681 tttttgtgaa atttcggctt atttccgaga agctacttct gaaacaccgt gaataagagg
     4741 ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc aaacaaaaat agttcctcat
     4801 attttacgtt tggttgagct tattaccgca gatgcaagct tttgaacacc gtttaagaaa
     4861 gaggtcgtga gcctgccgtt tcactctgag tcacaaagag caatttcaaa aaatagcttc
     4921 tcatgtttgt tgaatattgt gtcttgtgac cgaggagttg tcaggagaac accgtttacc
     4981 agaggttgtg acttgttttt agtcacgacc tcttttttta tttattccat ataaatacac
     5041 attatttatt ccgaaaagtg aaagcgcaaa taacaaaaac aaccaactta tttattatta
     5101 aagaaaagcg tatttaagta ggacgattct gttgagagct ttcgtagatt ttcccatttt
     5161 cctatggtaa actgacaaag ttgagaatgt tagaacagat cgtttaggag gaaacagatg
     5221 tttacgaatg aaataaaaat catgctttat gtggacgatg tagaaaaaaa tgcaacgttt
     5281 tggagagcag ttggctttgc ggaaaaagat cgtcaagaaa tggatgggac gcttataatt
     5341 gaagtaggag ttgaggacag tcaaacctca tttctgttat atgatcgagc atttgttgag
     5401 tcccattcac ctggcacagc tactagtgcc ccatctttga tgttttacag taaagatatc
     5461 tttggactat ataaaaaaat gcagacgcaa tcagtcacat taggtgatat ggtacagctt
     5521 ggagaagaat atgtctttaa ctttgctgat cccgatggca actactttgc ggttacaggt
     5581 aaataataga aataaagact ttgtttttct gtgcgaaaca ggaaagcgaa gtctttttaa
     5641 ttcaaataat aatattatgt aaacaaaaaa ctttccatgc gtaattatac acaagcaaat
     5701 aaatcgtcaa atgcgaacgc cttctttata ctgtttagga acgaaaagaa ggaaggaaga
     5761 aatacatgga ttatcaagta ctgctttatt acaattatac aaaaatcgaa gaaccagagg
     5821 aatttgccaa aaatcattta gccttttgca aatctttgga tcttaaaggt cgtattctag
     5881 tagctgaaga aggaataaat ggtactgtgt ctggaaccgt tgaaaacacg actgcctata
     5941 tgaaagcaat gaaagctgat cctcgatttg ctgatacgat gttcaagatc gatccaagcg
     6001 aaggacatgc ctttaagaag atgtttgtaa gataccgtcc agagcttgta agtttaaagc
     6061 tagaagagga cattgatcca aaccaagtga caggtgccta tctttcaccg caagaattta
     6121 aagaagctat tttagatgaa cagacagtgg tgattgatgc acggaatgat tatgaatatg
     6181 acttgggaca ttttcgaggg gctgtacgcc cagatatacg cagttttcga gagcttccag
     6241 actggatccg cgagcacaaa gaagaattta tggaaaaacg ggtagtgacc tactgtactg
     6301 gtggcattcg ttgcgagaag ttttctggtt ggcttgtccg tgaaggattc aaagatgtcg
     6361 gacagctgca tggcggtatt gctacttatg gtaaggatcc tgaagtccaa ggagaattat
     6421 gggacggcaa gatgtatgtg tttgatgaac ggatcgctgt cgatatcaac caagtagata
     6481 aacaaatcgt cggtcgcgac tggtttgacg gaacaccatg tgaacgatat atcaattgta
     6541 gcaatcctga gtgcaatcgt cagattcttg cttccattga aaatgaagaa aaacatttag
     6601 gagcatgtag catagagtgt gcgaaacatc cgcgcaatcg ctatgttcaa gaccatggaa
     6661 tctctccaga agaagcagaa ctgcggttta cagctttaat taaatagaaa acaatagttt
     6721 tgattgtcga ccatttccaa tatgcgctat actagcgttg aggatggtga tccacatgaa
     6781 atcattgatt tatgctattg gggatgtcca tggcaaacat gagctttttg aaaaacttat
     6841 tcactattat gatccaaaga tccatcagct tgttttatta ggggatctca atgatcgagg
     6901 tcctcgtaca aaagaatgtt ttttattagg aaagcaatta gtcgaagaaa caggagccat
     6961 ttacctccgg ggaaaccatg aagaatattt tttgcaattt ctgcaatcac cggaggactg
     7021 gtatgcgcct tatatgagaa atggtggaaa agaaacgttt gaaagcctga ttcacccagg
     7081 ggcatcggag gaatactccc caactgaaat ctcgatgatg atccaatcga gatattcaga
     7141 actgattaaa tttttagtcc agcgcccctt gtattatgaa tgggaaaatt atctttttgt
     7201 ccatgccggt gtggatttga caaagaaaga ctggcgtaag acaagtctaa gagactttat
     7261 ttggataagg gaaccatttc atgaagggaa aaacaataca ggtaagacaa ttgtatttgg
     7321 acatacgatt acaccaatgc tccatggaga tatgcagaca acagacctct ggattcagga
     7381 tcataaaatc ggaatggacg gtggggctgt attcggaggg tcattgcatg gggttgtttt
     7441 tgacaaggaa ggtattcttc aagatattga atatcagaac aacgaaggac cttggcatgg
     7501 aatctgacta atggaaagaa tgaaggagct gtgactttgt tgcggctctt tttattttta
     7561 tagagaatat tgtttctttc agtagtttaa cccaggataa aaagtatgat agaataaaga
     7621 agcaattttt agcagaaaag aggcatttta atgacggaaa atttgaacca gacgatcatt
     7681 cagcttgtac aaaaagaact ttcagactat cgtcctaagc agttgactac tgtacttaat
     7741 ttgttaaatg aaggaaacac tgttcctttt atcgcgcgtt accgaaaaga aatgactgga
     7801 agtcttgatg aagtccagat tcgtgaaatc gaagagcggt atgcctatct tgaaaactta
     7861 gaaaaacgta aaactgaagt gattcggcta atcgatgaac aagggaaact gactcccgag
     7921 ttagaagcag aaatcaccca agccgtgaaa atgcaacaag tggaagattt gtatcgtcca
     7981 tacaaacaaa aacgacggac aaaagcaacg attgctaaag aaaaaggact tgaaccactc
     8041 gcgaagtggc tgatgcagct tacagatgga gaggtgcaat ctgaagcaga aaaatatatt
     8101 gacaaagaaa aagaagtctc ttctgccgaa gaagcgttgc acggtgctca tgagattatt
     8161 gctgaacaag tcagcgataa tgcaaaattt cggacttgga ttcggtctta tacgtataac
     8221 aaaggtatgt atgtcagcaa tgtcaaggat gagcaagcag atgaaaaagg cgtatatgaa
     8281 atgtattatg actttgcaga acccgtccat aaaatggttt ctcatcgaat attagctact
     8341 aatcgtggag aaaaagaaga tattctgaaa gtattctttc aagtagatga agcagcaatt
     8401 ttagcttact tggatcgcca aatagtcaaa aatcctgcct ctccttcttc ttcattcgtc
     8461 agagaagcct atcaggatag ttataaacgc tttattcagc cagcaatcga gcgagaactg
     8521 cgcaatgaat tgactgaaaa ggcagatgag caagcaatcg ctattttcgg cgaaaacctc
     8581 cgtaatcttt tgttgcaacc gccactaaaa ggtaaagttg tcctgggatt tgatccggct
     8641 tatcgtactg gatgtaaact agcagtcgta gatgcgacag ggaaagtttt agcaatcgaa
     8701 gttatttatc ctcataaacc tgcagcgcaa gcaaaaagag aagctgctgg accagctttt
     8761 atccaattaa ttaataaata tcaagtagat atggtagcta tcggaaatgg tacagccagt
     8821 cgggaatctg aactttttgt ggctgagcag ttgaaatccg ccgaccataa aacctattac
     8881 gctatcgtca acgaagcagg cgcttctgtt tactccgcta gcgaaattgc acgaaaagaa
     8941 tttccgcatc tacaagttga agaaagaagt gctgtttcta ttgcccgtcg cctgcaagat
     9001 cctttagctg aattagtcaa aatcgatcct aaagctgtcg gagtaggcca gtaccaacat
     9061 gacgtttctc aaaaacgttt ggctgaacaa ttggattttg ttgtggaaac agcggttaac
     9121 caagtaggtg tggatgtgaa tacagcaagc ccgcagctct tgcagcatat atcaggattg
     9181 aataaaacaa ctgcccaaaa cattgtcatt tatcgtgaag aaaacggaga attcaccgca
     9241 cgaactcaat tgaaaaaagt gccacgctta ggaccaaaag catatgaaca agcaatcgga
     9301 ttcttgcgag tccctggtgg gaaaaacatt ttggacaaca caggtatcca tcccgaaagt
     9361 tattctattg caaaagaaat attaacttca gtccaacttt cagaaaaaga gcttggtaca
     9421 gaagaagcag tagaaaaatt gacacgatta tccgtagaga aactggctga aagcctatca
     9481 gtcggagaag aaacgttagc cgatatttta gctgggctga cacaacctgg acgagatatg
     9541 cgtgatgaga tgccagcgcc cttattacgt acagatgtat tgagtatgga agacttgaaa
     9601 ccagggatgg aattgactgg aacggtccgt aatgtcattg acttcggcgc atttgttgat
     9661 atcggtgtga agcaagacgg acttgtccat atatcgaaac tcagcaaaaa attcgtcaag
     9721 catcctacag atgtcgtgtc agtaggagat atcgtaacag tttggataga acaagtcgat
     9781 acgaaaaaag gtagaatcag tttgacgatg ctttcccctt atgaagagta acaatgagga
     9841 gtaacaaaaa ttgacacaag aagaactgca gcagttagta gaagagatat cattaaaaag
     9901 cttccagctt cctttcaagc accaagcaat gttcaatcca cgcttacgta caactggcgg
     9961 gcgctatcat ttaaacgatc atcatttaga ttttaatgcg aagctatttg aagagtcaga
    10021 cgaagagacg attgcaggaa tcatcaaaca tgaactttgc cattatcatc ttcatctagc
    10081 tggaagaggg tatcagcata aagatatgga tttcaagtat cttttgaaaa aaacaggagg
    10141 gttgcgctat gcaccagcct tgacgaagaa acagataaag atggagtatt atcgatgcca
    10201 agattgttct gccacgatct gccgcaagag aagaatcgat gtacgcaaat atcgttgtgg
    10261 aagatgtcat ggagaaatca aatggattga gacaaaaaga gaagacttta atgaagcaca
    10321 aaaaatcaga tgaaaggata gaaggccttt ggaaaaaagt gagcagagga atctaaaaga
    10381 ctggaatcag ctattaaatt ttttagccgc acctgaagag ggaaattttg aggaactgac
    10441 ggcacctaca cttattttag ctggaaactg tcttcctatc ttagctgata aagcagcaca
    10501 aatgtattta aatggccaag tagatcaatt gtttttggtc ggaggggtgg ggcatgcgac
    10561 tagaatcctt tatgagaatt ttgaaaagca aggatttcat tttgaagatg gcatgagtga
    10621 aagtgaaatc tgtcgtcagt atctaaaaga agtctatgat ttgcccgata aggcttttct
    10681 gatagaatcg aagtctacaa attctggaga gaacgccact ttttcactgg agattcttca
    10741 ttccttagga gctgtaccag aaaaaatctt attgatgaat gatccgacac tgcaacgcag
    10801 gactcgagca acttttgaga aagtatggca aaatgaacaa actattttcg cgaatgctgt
    10861 gccatttgtg ccggaaatcc ttcacttttc tgaagagatc atctttacag caaaagaact
    10921 gaatcatcaa tggcctaagg aatatttcca tgcgctagta ttaggagaaa tggaacgtct
    10981 ccatgacgat gagaacggct atggtccgaa aggaaaagat tttattcctc acattgatat
    11041 atcagaggaa gtttggtctt cttacaccag aattaaagag tcaataaaaa cggatttttc
    11101 tcgtacttga ccattttagc aagcgaatcc tcctttccaa ataaatttgg ttgaaatttt
    11161 caatcgttta taagataatg aggagcgtgt tgaatgtaat agctaaaaga atggacgcta
    11221 gataagagaa gaggattcaa atggaaaatc aaaataaatt gtatcatttt gttggtatca
    11281 aaggttcagg aatgagctcc ttggctcttg ttttacatga acaaggtcta aatgtccaag
    11341 gatcagacat tgaaaaatat ttctttacac aaagagattt agaaaaagca aatatcacga
    11401 ttctgccatt taacgcagat aatgtaaaac cagggatgac gatcattgca ggaaatgcat
    11461 ttcctgattc acatgaagaa atccagcgag caaaagaatt aggtttggaa gtgattcgct
    11521 atcacgactt tattggtcat tttatccaaa attatacgag tatcgctgta acaggctctc
    11581 acggaaaaac aagtacgact ggactgctct ctcatgtatt gagtggtgtc cgtccaacaa
    11641 gttatctaat tggagatgga acaggacatg gtgatccgca agcggaattc ttttcatttg
    11701 aggcctgtga atatcgccgt catttccttg cctattcacc agactatgca atcatgacca
    11761 atatcgattt tgatcatccg gattattata caagtatcga cgatgtattt acagctttcc
    11821 aaacaatggc tggacaagtg aaaaaagcta tttttgcgta tggtgacgat gcttatttac
    11881 gcaaattaaa agcaaatgtg ccgatttatt attatggtgt cacagaaaac gatgatatcc
    11941 aagcacgaaa catcgaacgc acaacttctg gttctgcttt tgatgtctat catggggatg
    12001 aatttgttgg gcacttcact gtaccagcat tcggtaaaca caatatctta aatgctttag
    12061 gtgttattgc agtagcttat ttcgaaaaac tggatctgaa agaagttgca gaagaaatgc
    12121 tgactttccc aggagtaaaa cgtcgattca gtgaaaagat cgtagcagac atgaccgtag
    12181 tcgatgatta tgcgcatcac cctgcagaga tcaaagcaac gattgatggc gcacgccaaa
    12241 aatatccaga taaagaaata attgcagttt tccaacccca tacgtttacg cgtacgattg
    12301 cattgatgga tgaatttgca gaagcacttg atttagctga taaagtttac ttatgcgata
    12361 tttttggttc ggctcgggaa gaacaaggaa acgttaagat tgaagacctt ggagcgaaaa
    12421 tcaaaaaagg tggagaagtc atcaaagaaa ataatgtatc tccattgtta gattatcatg
    12481 atgcagtagt aatcttcatg ggtgctggag atgttcaaaa atttgaacaa gcgtatgaaa
    12541 aacttttaag cagcacgacg aaaaatgtac tgtaatacaa ttactgcagt gtccttataa
    12601 aaatagaaag agggggagtg gcaaaaatct tgccaagccc ccttttttgc aacttatgat
    12661 aaacggtgtt caaaagcttg catctgcggt aataagccca atcaaatcaa aaacatgaga
    12721 agctgttttt tcttggctgt tcttattatt tgatgcagga cagctttttc acgacctctg
    12781 taaactatag gaatctgtta aatcaaggga gcagaacttg ccttttacgc tacttttggt
    12841 acaataatgt atgattaaaa ataaactgga gggtttctat cttgaacata ggtaagccga
    12901 gaaaactagg aaaaacaata aatgaaatcg aggaaggcga ctcgttatcc ttaacagaat
    12961 ctattgaaga taaccagctt ttgctgtatt tgggattgac gaatgatgca aatcctttgt
    13021 atatccaaca tgactttgca caaaaaacag aatatcaaca gccaatcgtt ccatcagtga
    13081 tgctgatggg gatcatcaca agtgcaattt caaagcatct tcctggacca ggatcacatg
    13141 ttgtcaattt ttctgtcaat tttattgaac cggttttcca ttatgaaaca ctgacttttc
    13201 agtttgaggt cataaaagta gataagatga aggatgtggt gacgatttct gtagaagcgg
    13261 agaatacgaa cgaagatcgt gtgttggatg ctgtcgttat ggtccaaccg ccacaagttc
    13321 ctgaattgga aatagcaatc gaaagtgaag gtgaattgaa tgaataatcc aagtacatca
    13381 atgtcaggta tcaatcgttt ttatgcaaaa gtttatggat ttttaggtat gggacttgcc
    13441 cttagtgcag tcacttctta cttggctctt tgggtatttc ctttgcaatt agcaactttt
    13501 atcaataatt ttccactagg ctttgtgggt ctgtggatcg ttgaactgat tttagtaatg
    13561 gttctaggcg taaaagcaca aaagaatccg agcttagcaa tcggtggatt tattgcctac
    13621 tctcttttga atggcataac attagcggtt actcttgcat actacgatat tggaacagta
    13681 acgcaagctt tcttgacagc tactttgatg ttcatgggga tgtctgttgt cggagtaaca
    13741 acaaaaagag atcttagcgg ggttggaaga gcaggacagg cagctttaat cggagtgatc
    13801 attgcactag tcttgaacat cttcattttg agaagtagcg tagttgagct gttcatctcc
    13861 ctactgttag tcgtcatctt tgcagggatt acagcttatg ataaccaaag catccgtaat
    13921 atctatgtcc agacaaacgg aacagcacat agtggaattg ctgtattcat ggcattgaag
    13981 ctgtatttgg actttatcaa cttgttcttg gcgtttctga gaatctttgg acggaacaac
    14041 taaaaaagaa aaaaattcat cagttggggc tataccgaat tatttggtat ggtcccgctt
    14101 tttcttttcg cattccgcag gattctttgt tagaatgaat aagaacttta cagtaaggag
    14161 ttaagaagat gacaaaaaat aaattattac tcgttgatgg gaacagtgtg gcttttcgcg
    14221 cattctttgc gcttcacaat tctcttgaac gtttcaaaaa tagaaacggt cttcatacaa
    14281 atgcaatcta tgcattcaat acgatgtttg aaaatgttat gcaaaaagag caaccgactc
    14341 atgttctggt tgcgttcgat gcaggaaaaa cgacttttcg gacagaaatg tatgcggagt
    14401 acaaaggtgg aagatccaaa acacctggcg aattcaaaga acaaatgcca tatatacgtg
    14461 atttgttgac aggactaggg gtacagtatt acgaattgcc caattatgaa gcagatgata
    14521 ttatcggtac tttggcagaa aaagtagaca aagatcaatt tgatgtcgtc gtgctttcag
    14581 gtgatcggga tttgactcaa ttagctagta aagaagtaaa agtggatatc actgtaaaag
    14641 gtgtcagcga tatcgaaagc tatacaccag aacatgtagc ggaaaaatat gatgggttga
    14701 cgccaaaaca gattattgac atgaagggac tagccggaga tgcctctgac aatatccccg
    14761 gtgtgactaa aatcggtgaa aaaacagcta tcaagctatt gaaacaatat ggctcagtcg
    14821 aaggaattta tgaacatatc gatgaaatga agcaaagcaa aatgaaagaa aatctgataa
    14881 atgacaaaga gcaggctttc ttatcgaaaa aattggcgac catcaatact tcagcgcctg
    14941 tggatgtctc tatcgactca ttgaagtatg aagggaaaaa tctcgataaa ctcgttccgt
    15001 tttataaaga aatggatttc aatcagttcc tttctaaatt gaatatcgta gaagaagaag
    15061 taaaaatgga tgatattttg tttgaagtcg ttcatgaatt caaagaggaa atgtttacta
    15121 cggatatggc gttgtacgtg gaaatgatgg gcgacaatta tcatacagag gaaatcgtcg
    15181 gagtagcgtg ggggacagaa aagaaaattt atgtcacgaa cgatctatct gtattcgaaa
    15241 accgagcgtt ccattcttgg atcactgatc cgactcggct gaaaaaagta tatgatgcga
    15301 aacgaactta tgttgcttta aaccgctata ctggaaaaac gaaaggaatc gattttgatg
    15361 tcttgctagg tgcatacctt ctcgatacga atgaaaaaag cacagatatc gaaggaatag
    15421 ctgctcatta cggatacaac gatatccaat cagatgaagc tgtatacggc aaaggggcga
    15481 aaaaaggttt accagaagaa gaggaactct tttttgctca tttagcgcga aaagtagctg
    15541 caatcaatgc gttgacacca aaattgagcc aagaactggc agaaaaaaac caagaagatc
    15601 ttttccggaa aatggaactg ccattgtcta tcattttggc agagatggaa ataagcggga
    15661 tcaaagtaga tgcgactcgc ttacaagaaa tgaagggcga gttctctgct cgcttaagag
    15721 agatcgaaca aaaaatctac gaagaagccg gcgaagaatt caatttgaat tcaccaaagc
    15781 aattaggagt gatcttattt gaaaaaatgg gattacccgt tatcaaaaaa acaaaaactg
    15841 gatattccac agccgtagat gtactggaac agcttcgtga acaagcacca atcgtagagg
    15901 atatcctcac ctatcgtcaa attgcaaaaa ttcaatctac ctatgtcgag ggactgctga
    15961 aagtgatcca atcagatgga aaagtgcata cccgttatgt ccagacattg acccaaacag
    16021 gacgattaag ctctgttgat cctaatttgc agaacatccc gattcgatta gatgaaggga
    16081 gaaagatacg tcaggcattt gttcctagag aaaaagactg gctgatttat tcttctgact
    16141 attcacaaat cgagttacgc gtacttgcgc atatctcaaa tgatgaacat ttgaaagctg
    16201 ccttcctaga aggtcaagat atccatgcca gcacagcgat gcgtgtattt ggaatcgaaa
    16261 aggcagagga tgtcacacca aatatgcgta ggcaggcaaa agcagtgaat tttggtatcg
    16321 tgtatggcat ctctgattac ggactttcac aaaatctagg aatcagccga aaagcagcac
    16381 agcaatacat cgatacgtac tttgaaaaat acccaggtgt caaagaatat atggaaagaa
    16441 tcgtacgcga agcaaaagac caaggctacg tcgaaacgct gtatcaccgc cgtcgatatc
    16501 tgccagacat caattcaaga aattacaata tccgttcttt tgcggaacga acagctatca
    16561 atacaccaat ccaaggaagt gctgctgata ttttgaaaat cgcgatgatc gaattggata
    16621 aacgattaaa agaaacaggt cttcaagcta cgatgctgtt acaagttcat gatgaacttg
    16681 tcttcgaggt accggaaaaa gaacttgaat cattagataa attggtgaag gaagttatgg
    16741 aacaagctgt ttctcttcat gtaccactga tcactgacag cagttgggga aaaacgtggt
    16801 acgaagcaaa ataaacattg tttaagacag agcaatataa tgaaggtgaa aagaaaaaat
    16861 gccagaatta ccagaagtag aaaccgttcg taaaggattg gaacggttag tagtaggaaa
    16921 aacgattcaa aaagttcagg tcttgtggcc caagatcatc gagcaaccag agacacccat
    16981 ctttgaggct tctcttgttg gcgaaaccat ccaatccatt ggacgtagag ggaagttttt
    17041 aatttttcat ctcgatcatt gtgaactgat ctcacacttg cgaatggaag gaaaatatca
    17101 atttacgaaa gaaaatacac caatcgataa acatacgcat gtacttttct tttttgagga
    17161 tggaagccaa cttcgctaca acgatgtacg aaaatttggt cgtatgacaa tcgtcgaaaa
    17221 aggagcaagt gcaacttacc gaggaatcat gaaattggga cctgagcctt tgccagatag
    17281 cttcttatta gcagatttcg caaatggact gaaaaagtcc cacaaagcaa tcaagccatt
    17341 gctgctagac caacgtctag tgactggtct aggtaatatt tatgtagatg aagcattatg
    17401 ggaagcgaag atccatccag aacaaccggc gaacacactg cgccccaaag aggtagaaca
    17461 attacgtcta tcgatcattg atgttttgga tcgtgcaata gaagccggag gtaccacgat
    17521 tcgcagttat ttgaatgcat taggagaatc aggcggattt caagtagcac tgcatgtcta
    17581 tcagcaaact ggcaaaccat gtatacgttg tggaacgccg atcgtgaaaa caaaagtggc
    17641 acaaaggggg acgcactatt gtccgaattg tcaaaggcta aaaatcgcaa agtaggattt
    17701 gttttaggtt tgacgggtgg aatagctacc ggtaaaagta cggcagccaa agtctttcag
    17761 tctcatggat ttcctttgat cgatggcgat gtgattgcca gagaaactgt tgagcctgga
    17821 acgcttgctc tgaggaaaat tgtatcagtg tttggccaag aggtattgca gcctgatggg
    17881 caactagatc gagggaaact tgggatgatt gtttttccat caaaggaaaa acggcaaaaa
    17941 cttgatcagc tattagatcc gtttatccga aaagcgataa aagatcaaat cgcctctcta
    18001 agttccaatc atcctttagt aattgtagat atcccattgc tctacgaagg tcattatgac
    18061 cactatatgg atgcagtagc tgtcgtttat actacgccag aaactcagct tcagcgtttg
    18121 atgaaacgta atcaactgac gctagaacaa gcgcagcaga gaattagtag tcaacttcca
    18181 atcgaagaaa aaaagcagcg tgcggatatt ttgttcgaca acaatggaac aaaagaaaaa
    18241 cttgtgggac aaatcgaaaa ttggcttttt gctaatcgct ttctttgagt atctgtgtca
    18301 attttgctat cctgagtata tagaaagtga gggatagcga tgggatcatt aaaaaatcaa
    18361 aaggataaag tcgtaggtaa cgcaaaagaa aaaatcggcg agatgctcaa taaagaaaat
    18421 ctaatcgatg aaggtcgtac gcaatcagaa acagcagaag aaaaagaaaa gcagtaccaa
    18481 gcaagaatcg atgaaataga agaccagcag gcagaagaag aagcgaagcg gcaagatttg
    18541 actcaagaac gaaaaaatcc gacacctgat cgtagtaaaa caccgctccc agaaagtgac
    18601 cacattcccg atgagcaaaa aatcgaggaa cagcgaatga aacactatac aggaatcgaa
    18661 gagaagttat aaaatagtaa aaaatcgaga tgtgacttga agcagatgag aaggtgttca
    18721 tctgcttcaa gttttttgtg ctagatgact aaatcagctt ttgtgtaagt tatttctcag
    18781 taatcaaggt gatcagtatt ggaaaattga aatttagtaa ggacagggga cacaattacg
    18841 catgaaagta gaaaaaattg ttcttatatc cgtgtttttt gggtaggaca gtcgcgtttg
    18901 tgatttgttt cgtgttataa tacaactagt tgtaaagaaa gacacatcct ttatataaaa
    18961 tgcgatgcaa gaggtgagac aaaatgagat gtcccagatg tcaacataat aattcacgag
    19021 taatcgacag ccgtcaagca gatgatggac gtgcgatccg tcgccgtcgc gaatgtgaga
    19081 attgttcgtt ccgattcact acatttgaac gaattgaagc tgctccgtta ttagtaatca
    19141 agaaaaacgg ggaacgcgaa gagttcaatc gcgataaaat tttaagagga ctcatccgtt
    19201 cagcagaaaa aagacctgta gctatggaac aaatggaaca aatcgtcaac catgtcgaaa
    19261 accgcgtacg cagtctcgga gaaaacgaag tatcgacgaa tctaattggt gaatatgtga
    19321 tggaagattt agttgattta gacgaaatcg cttatattcg ttttgcaagt gtttatcgcc
    19381 agttcaaaga tatgtctgtt ttcttaaaag agttgcaaga tatcgtggat aaagcaaaag
    19441 aaaataataa agagaataat aaagaaaaca attaagaaac aaaaaggagg catttccttg
    19501 gaaaatgctt ggaaagagct tcaaccaaaa aatatttacc aaggaagaaa agcggctccg
    19561 ctgagagaag acagcaagaa cgccttgctg tatctttatc agccactaat cggcggagaa
    19621 gccttgagta tctatttcac cctgttatca gaaatctctc aagaatctgg caaaggtcct
    19681 gaagggatgc atgcagatct gcttagtagt ctaggctgcg gtatcccgca attttatgat
    19741 gcaagaaaaa agctagaagg aatcggctta ctggatgttt attttaaaga agatagtgat
    19801 ctgggacctc gttttattta tgagctgtta gaaccactca ttcctaaagc atttttcaaa
    19861 gactctgttc tggcttttct tcttctggaa aaagttggtg aacgacgatt ccagaagctt
    19921 acccaattct ttgaacctaa aaggcataca gcagagggat atcaaaaaat cacaaaaaaa
    19981 tttttagatg tttatcgctt caatgaagca gtgtacgctg ctaatcaaga aaacatcgaa
    20041 tcgctgaata aatcttttga agaatctgaa tcagtagcat tacttgaagc agattcgaca
    20101 ttcgattggc agtttttgaa tgattggctg gcaaaaaaac atattgcaag tcttgatgat
    20161 ccaatcatca aacaagtcga catgtatcat cagctttacg gtttcgatga attgacactt
    20221 ggcgaactga tcagtcaatc ttatgacttt agtgaacaaa aagtatctga aaaagaactg
    20281 caaaaagcca ttttggcaat gcagagacgt ccggtgaagc aaacaaaaga aacagttgcg
    20341 gtttctgaaa acagtaatga accctcgtca aacgaacatt tgacaaacgc agcgcttcag
    20401 ctgataaaag aagcacagag cattccaccg atgaaatatc tggaagcaat caagtcagaa
    20461 aaaggcggat atgtttctaa acaagaaaac tggttactgc aagatcttgt ttctcaatca
    20521 ggtctttcca gtagcgtgat caatgttttg ctgaattatg tactagtgat caagaataat
    20581 gctagcttaa atgccagtta tgtaaataca gtggcaaatg aatgggcaca aaagaaaatc
    20641 gccacagcag aagaagcgat ccagcacatt cggcaaataa gtaatcaagc aaaacaatca
    20701 aaacaaaaga agcaaacaaa ttatcaaact ggcaagcgaa atgttcgacg ggaaaagctt
    20761 cctgattggg tcaaccagcc aaaagatgaa aaacagatca gcagcgagaa aaaagcagag
    20821 attgaccgcc gttttaaaga atacctggca aaaaaggagg gtgatatcta gtggaagacg
    20881 taggcaaaga attgaagagg atcatcagca aacgcaatta tcaagaaaag tatgctgaaa
    20941 tgatcgctga agtcttaaat gatgcggatg ttcaagcttt tctaagcgca caccaagaag
    21001 aattgacaca agcggatatt gaaaaaagtt acgctaaatt gtatgaattc gtgcaagaaa
    21061 agcgtaaata tcaaaaaaac gatccaacga tgatcgctcc cggctatgag ccgaagctga
    21121 cgttgaattt tcattatgtg gatgtcactt atgtaccaac ggaagcattg ttagcacggc
    21181 aaagacaaga agaaatcaga agccgagtaa aagcaatgga tatgccaaaa gatattcaat
    21241 cggcttcttt tgaaaacttt gaacgtacag atggacgagg atatgcgagc ttagaagccc
    21301 tagattttgt agagaaatat actgctgatc caaaagggta tcataaagga ctgtatctag
    21361 taggaagttt tggtattgga aaaacatatt tattaggagc aacagcgaga gaattagcga
    21421 ttgctggatt caccacgacg ctagtccatt ttccgacatt tgccgttgag atgaaacagg
    21481 caatcggaaa agatcaagtg gcagaaaagt tagatgcagt gaaacgttca cctattttga
    21541 tgatcgatga cattggtgca gatgcgatga gtagttggat acgagacgaa gtattcggtg
    21601 ttatccttca atatcggatg caggaacagt taccaacctt cttctcatcg aattttacaa
    21661 tggatgaatt ggaacagcat ttgtccgtca ctcaacgtgg agatgaagag ccgctaaaag
    21721 cgaaacggat aatggaacgc atacgttatt tgacaaaaga aatcgaaatg actggtcgca
    21781 accgacgcaa tggttgaaca gttgacaagt ccaactgaca tttgacctag tagtaaaagc
    21841 aggtcagcga atcattatat ggacagaaat gaccggagac aatcaccgca acaagtaatg
    21901 cagaaactta aacggaggat tttttatgag ggctattttt tctagtatat ctgtagttgg
    21961 tctatttttt cttttagcag gctgcggtag cgcagatagc aacacaggtt ctgttgattc
    22021 gattgatgcg ggtcaaacag taaaaacaag cagtacgaaa acggagagac aaagcatatt
    22081 tgtcggaacg attgaaagta tcactcaagt agaagcagaa gaagaaacgc ttcagttgaa
    22141 actcgtcgat gtcatggcca aagaagatcc agcgaatatg ggaacgtcat tcagcaatga
    22201 cggagtgatc ttaaatgcta ctgctgaaaa aataagcgtg gacataaatg aattgaaaat
    22261 cggtgacaaa gtccaattta cattagttga gatgccgatc atgacgatgt ctatcccacc
    22321 gcaagttcct ggagattcga ttattgatgt ttcattgaac aaataaccaa taacattttt
    22381 tcaaaaataa gaaaatgttg ttttatagaa cgaaaaggta tattttttaa ggagatatgg
    22441 gaattttttt attcctagtc tccttatttt atttggaaaa tgctataatt atctagaagg
    22501 agtgaagcta tgaaccattt agatttatct cagcgcttag ccgcagtggg tgactttgtc
    22561 cctgaatccg ctcgtttagc agacattgga tcagatcacg cttacttacc cgttgcattg
    22621 atattaagag gaaaaatcga atatgcagtt gctggtgaag tcgttcaagg tccttatgaa
    22681 tcagcacgta agcaagtcaa aaaagatgga ttagaagacc gtatcaccgt acgccttgca
    22741 aatggtctag atgctatcca gccacaagat ggtattacag ctgtcacgat tgcgggtatg
    22801 ggaggttcac tgatccgaga tatcctagaa gctggcaagt tgaatcaacg cttaagcgga
    22861 caagaacgtt tgatccttca gccaaacatc ggagagcgta cattacgatc ttggctgcaa
    22921 gaaaatcagt ataaaatcca atcagaaaaa atacttgaag aaaataaaaa aatatatgaa
    22981 atcattgtag ccgaaaaaga acaaaaacca gttacttaca atgaaatgga gctgatgttc
    23041 gggccatttc tgcttgaaga gaaaagtgag atcttcaaat caaaatggac aagagagctt
    23101 caacaaagaa aagctatccg tgaacagctc aaacaagcag ctaatcaaga ggcacgtcaa
    23161 aaacaaatcg agcaggaaat ccaaatgatt gaggaggttt taaagccatg acaatcagcg
    23221 gacgcacttt catccaaaag tttgaaagct attgtcctca gtggctagct gaagaaggag
    23281 acccagtcgg actgcatatc ggaacattgg ataagccaat ccaacgagta atgatgacat
    23341 tagacgttcg tccagaagtg gtcgaagaag caatcaagaa aaaaatcgat ttgctgattg
    23401 ctaaacatcc tccaatcttt cgtcctgtaa aacggctggt tactgatcag ccacaagaaa
    23461 aaatgtatgc agatttgttg aaacatgata ttgccgtcta tgcagcacac acgaacatgg
    23521 atattatttg ggatggactg aatgactggt tttgtgaact tctcggtatt gaagtggaga
    23581 gttatttagt aaagactcat gagattcatt ataaaaaact ggccgtttat gtacctgtgg
    23641 atcatgcaca gaaaatgcgt gaagtattag ctgcagctgg tgctggtaca caaggtgatt
    23701 ataccggtac aagttttacc tcgattggac acggtcgatt tactccggaa gctggtgcac
    23761 aaccagcgat tgggaaagta gggaagacag aacaagttca agaggcaaaa gttgaggtta
    23821 ttttgccgga aactatcgaa aaacaagtga ttcaagccat gcggtcagct catccttatg
    23881 aggaacctgc ttatgatctt ttcgctatag atgaaccagt cgaaatgttt gggttaggac
    23941 gagtaggtga attgccgcaa gaaatttcta tagaggcatt tgtagaacaa gtaaaagaag
    24001 cgttccaact agatggactg agaatagtcc agccaaaaaa tgcaaaatcc tctgtgaagc
    24061 gcattgcgat ttgcggtgga agcggtgaaa aattttatcc gcaagcaatc gcccaaagag
    24121 cagatgtcta tatcacggga gatatctatt atcatacggc tcatgatatg caaagcgctg
    24181 ggttgattgc aattgatccc ggtcattata ttgaatcgtt atgcaagcaa cgatttatcg
    24241 agaaatttga atcttggaaa caagaagaaa attgggatat taactttttc gtttctgaaa
    24301 caaatacaaa cccatttcaa tttaattaaa aggagagaat actatgtacg aaaatctttt
    24361 gccacgtttt ttacgatatg tcaaaacaga aacacgctcc gatgcaacaa gcaaaacgac
    24421 tccatcgact cagacacaag ttgcttttgc gcaagaattg aaaaaagaat tagaagagtt
    24481 aggcttagct gatgttttct ataatgaaga taacggattc gttatgggaa cattaccaag
    24541 caatgttgat catgaagtgc gttccattgg atttatttcc cacatggata cagcagattt
    24601 taatgcagta ggagtcaatc cacaaatcat tgaaaactat gatggcgagt ctacgatcgt
    24661 actagatgcg gaagaacgct atacattgaa tacaaaagat tttccaaatt tgaaaaatta
    24721 tgaaggccac acattgatca caacagatgg cagtacatta ctgggagcag atgacaaatc
    24781 agggattgcg gaaatcatga ctgcaatgga gatcttgatc aataatcctt ctatccctca
    24841 cggtaccatc aaagtggctt ttggtcctga tgaagaaatc ggtgtcggag cggataaatt
    24901 cgatgttgag caattcgatg tagattttgc ttatacagtc gatggtggtc ctttaggtga
    24961 gttgcagtat gaaacgttta gtgctgctca agcaaatatt acgatccaag ggaaaaatgt
    25021 acatccaggg acggcaaaag atacaatgat caatgctcta cagttagcaa tcgattttca
    25081 taatcagctt ccagccgatg aagttccaga aaaaacggaa ggatacgaag gtttcttcca
    25141 tttgatggca ttggatggga atcctgaaga agcttctatg agttatatca ttcgcgatca
    25201 tgatcgtgaa aaattcgaag cacgcaaagc acaaatcaca catatccaag aagagttgaa
    25261 tcagcgattt gatcaagaac gaatcaaagt agatatgtat gatcaatatt acaacatgaa
    25321 agaaatcatt gaaaaagata tgagcatcgt ggaattagcg aaacaagcaa tgatcgagct
    25381 tggtatctct ccagtgatcg aaccagttcg tggaggaaca gatggttcaa aaatctctta
    25441 catgggtatt ccgacgccaa atctatttgc cggaggagaa aatatgcacg gacgattcga
    25501 atttgtttct ttacaagtaa tggaaaaagc aacagacgtg attgtaaaaa ttgcagaatt
    25561 gaacacaaag agttaaaatc gaaaaagaac agcttatgac aaggcgttcg tcccaatgat
    25621 ggaatgtcat ctgtctaagg ctaaagggca ggacaatgga attggttgtc ccgccctctt
    25681 ttttgaagag taaataggag gtaaagaatg gaaaagctgc tagtttttta taacaaaagt
    25741 tcagggaaag atgagggtga gaaattagca cgctggtttc aagattatgt aaaagaaaag
    25801 cagccagaat tatatgtaga actagctgaa actggcccat cgattgatga tgcggaatta
    25861 gtcaagaaag cagaagccat agaagctgat actttagtaa ttataggtgg agacggcacg
    25921 attcatcata tcgtccaagc gttccaaaaa acattatctc aataccatgt cggattactt
    25981 ccaggtggaa ctgtcaacaa ccttgcacgt gttcttgaga ttcccctcaa aaaagaagaa
    26041 gctgctgacg tgatcctgga aggcaatgta cggaaaatag actatggtca agtcaatgat
    26101 gaagtcatta tctctacact gacaatcgga atcttagcag atacagcagt ttggatcagt
    26161 caagaagaaa aacagcgtta cggctcgtgg atctttatca agaagttttt taagttattg
    26221 ctgaagaaga aaaaatatca tttggattta gaaacagacg aggagcattg gaaaggaaaa
    26281 tcccaactgt tgacagtcac gatgtctaac tccgtgggcg gttttacaaa ttttgacgac
    26341 tcagcgaccc tagatgatgg aaaatttcat gtaacgatcg taccttcctt agatattttc
    26401 cgatttattt tttatttgcc tagaatcatg agaggcaaat tctatacgat ccccggcatt
    26461 acttatttca cagccaaacg catgaaaatc caagcgcagg aaaaatctgt gggcactcga
    26521 acggatggag acacgacaga tgatcttcca gttgaattat ctgttgtatc aaaaggatta
    26581 acagtttatt caccaaagaa agaagaaaaa gcttagaaat agtagttaac agaaagttgg
    26641 aagaagagta atggatgtat tgttacacaa tcctttgtgg ttttaccttt tcattgtgaa
    26701 tttttactta ttttgtctga tggggtatga taaacatcag gctagaacta gcggctggcg
    26761 tgttcctgag aataatttga tatttgtcag cctgttaggc ggtggtttgg gaggattgat
    26821 ctctcgaaaa gttttccatc ataaaactcg gaaaaagaag tttactatag gattcgctgc
    26881 aggtgtactt gttgatttga ttctcattta ttttttccat taaggagcag gagatgtcgt
    26941 ctaaaggaac gaaaactaaa atcattctga atctgctttt gctgattgtg atttttgcca
    27001 ttatttatta tttaatcaat caatcatttg cagatatctt tgccgaattg ctgtctacca
    27061 gtgttgttgt tttggcagcg gctgttatat tagggacagt ttaccaaatc gctgaagggc
    27121 gctcaatcaa agaaattgct gaacctttcg cgccgaattt tacaacgaaa gatgggttct
    27181 tgacctctag ctatattgcg ttttaccgaa tcgtttcgtt tggtacagga acgctgatct
    27241 cggagattta tttttataac aaaaaaggaa tgaagctatc ccagggagca ggggtgacag
    27301 cactccatat gattatgtac aaactggcag tgatcactta tgcattagct ggcttggtca
    27361 tccaattctc tcttttttat tctaatggtc catcaatgat ctggtttatc atcgctggta
    27421 tccttttgac gatcgtgatt gttgcctttt tattggcgat gtccgtcagc ttgaatgttc
    27481 aaatattttt tgtcagctta tcgaataagt tatttaaaag tgagcgtttg cggaaatggg
    27541 tggatacatg caatcagcag atctactctt taagggaaac ggtccaaacc attatccaag
    27601 acaggactgc gctattgcgg atttatctat ggaatatgtt aaaacttgta ttttggtatg
    27661 tacttcctta tttgattctg attgaaaacc atcctaaaat agattttcta ctgaccattt
    27721 cgtttatcag ctttgcagta gtgctttcag gggttattcc tacgcctgct ggtattggtt
    27781 cctttgaatt tgtctatttg ttattattca gaccagttgt tggaacagtt gacgcagttt
    27841 cttcgctttt actgtatcgt ttcagttcct ttatcttgcc atttctctat ggatttgtgt
    27901 atgtgattgc tgaacggcga agagtgatca aagaagaaat aatagaagta aaaaaagaga
    27961 ataaagaaaa tcaagggtag gtcttttata agatctaccc tttttatcaa atcaaagaaa
    28021 aacgttatgg ataagataat tttacgtttg tttggctctt tttttatata catacaatca
    28081 attttgtttt tttaagattt atataagtcg agaaaaaaag tcaaaaaact atgtgtatat
    28141 tttgaccaaa attgaccaaa gcgatataat agtttttgta aagatcaaag aaataagtga
    28201 tcttaccttt aattaggagg gtatacctgt atgaatattg agaaaatgac tacgacgctt
    28261 caagaagcga ttgctgaagc tcaacagatt gcggtcactc gaaaacatca agatatcgac
    28321 attgcccatg tatggaaaat ctttttacaa tctaatcatt ttggtcgaaa tttctatacg
    28381 gatgccggat tggatgtcga atcttttgaa catgaaattg atcgtctact ggatgagtat
    28441 ccagttgttt ctggtggaaa cgtccaatat ggacaaaacc tcagccagaa tttctttcga
    28501 ttattgaatg aagcagacca aatacgtgaa agcttcggcg acgagtttct ttcaacggaa
    28561 gtcgttattt tagcgttgat gaaattaaaa aattatccgt taactgttta tttgaataaa
    28621 aacggattat ctgaaaaaga attgcgtaaa aacatcgaag agatgagagg aggagaaaga
    28681 gtgacctcac aaaaccaaga agaacaatac aaagcattag aaaaatacgg cgttgattta
    28741 gtacagcaag tcaaaagcgg aaaaatggat ccaatcatcg gtcgtgatga agaaatccgt
    28801 gatgtcatcc gtattctttc acgaaaaaca aaaaataatc ctgttctgat aggagaaccc
    28861 ggtgtaggga aaacggcaat cgttgaaggg cttgctcaac gtatcgtacg caaagatgtg
    28921 cctgaaaatt taaaagataa aacgattttt tcattagata tgggtgcatt gatcgctgga
    28981 gcaaaattcc gtggtgaatt tgaagaaaga ctaaaagcag tcttgaaaga agtcaaaaaa
    29041 agtgatggac gtatcctctt gttcatcgat gaaatccaca atatcgtagg ggcaggaaaa
    29101 acagaaggaa gtatggatgc cggaaatctg ttgaaaccaa tgcttgctcg cggtgaatta
    29161 catttgatcg gtgccacaac tttagatgag taccgtcaat atatggaaaa agacaaagcg
    29221 ttggaacgtc gctttcaaaa ggtattagtc aaagaaccaa cagtggaaga tacgatcagt
    29281 attctgcgtg gattaaaaga acgttttgag atccaccatg gtgttaacat ccatgacaac
    29341 gcattagtag cagcagctac tttatctgac cgttatatta ctgatcggtt cttaccggac
    29401 aaagcaatcg atttgatcga tgaagccagt gcaacgattc gggtagaaat gaactctatg
    29461 ccaacggaat tagatcaagt tactagacgt ttgatgcagt tggaaatcga agaagctgca
    29521 ctgaaaaaag aatcagatga tgcaagtaaa aaacgcttga aaaatttgca agaagaatta
    29581 gctgaacttc gtgaagaagc aaatgcgatg aagatgcagt gggaaacaga aaaagaagaa
    29641 gtcaattctg tttcagcaaa acgtgctgaa atcgataaag caaaacacga attagaagat
    29701 gcagaaaata actatgattt agaacgcgct gctgtattgc gtcatggtac gatacctcaa
    29761 ttagaaaaag aattgaagga attagaagct aaagcaaaag acagcgagat taagatggtt
    29821 caagagtccg ttaccgaaaa tgagattgct caagtcgttg gcagattaac gggtatcccc
    29881 gtaacgaaac ttgtagaagg tgaacgagaa aaactaatta aattgaatga aacacttcat
    29941 aaacgagtga ttggtcaaga tgaagcagtt gatgcggtca gtgacgcggt aattcgttca
    30001 cgggctggat tgcaagaccc aaatcgtcct ctaggttctt tccttttcct aggaccaact
    30061 ggtgtcggaa aaaccgaatt agcgaaagcg ttagctgaga acttgtttga ctcagaagat
    30121 catatggtac ggatcgatat gagtgaatat atggaaaaac atgctgtgtc tcgtctagtc
    30181 ggagctcctc caggctatgt aggttacgaa gaaggtggtc aattaacgga agctgtcaga
    30241 cgaaatcctt atacaatcgt cttgttggat gaaatcgaaa aagcgcatcc cgatgtcttc
    30301 aatatcttgt tacaagtcct agatgacgga cgcttgactg attcaaaagg gcgagtagta
    30361 gatttcaaaa atacggttct gatcatgacc agcaatatcg gttcacagtt actgctggaa
    30421 ggcgtgactg ctgatggaac gattccagaa gcagtggctg aacaagtcaa cacgctatta
    30481 cgtggaaact tcaaaccaga attcttgaac cgaatcgacg acacgatttt atttacacca
    30541 ttgagcctag acaacgtgaa aggaatcgtt gacaaaatgg tggcgcaatt ggcacaacgt
    30601 ctggaacatc aagaaatcct gctgacaatc agtgatgaag ccaaaacgtg gattgctgaa
    30661 aatgcttatg aaccagcata tggtgcaaga ccattgaaac gatttatcac taaggaagta
    30721 gaaacaccac tagctaaaga aatcgttgca ggacatgtta tgcctaaatc aaaagtaacg
    30781 attactttac ttgatggaca acttcatttc aaaacagaag agctagaaga aatcgtctaa
    30841 tcttccattg agactataaa agaaaaaagg ggtctgacac aactagtgtc agacctcctt
    30901 ttttcaaata aacagtgttc cagaagtagt ttcttcgaaa aataagccga aatttcttga
    30961 agctgcccgc ttctgtcaca acctctttta ttaggtattt ttcacttttt ctaatttata
    31021 actttcaaag taacgctcat cttttttact ttgagaccat gcaaacaatc ccattaaggc
    31081 agcacctatc gtatttgtca gcaagtcgcc catcgtatcc atcaatgctg ctcgtccgac
    31141 aaacagtgtg ccatcagaag cagcaaaacg ttgaagattc atgcctaaga actggtcgca
    31201 taagaattcc cagaactccc aaaacacgcc gcaaagtcca gcaaacgcaa agccgaataa
    31261 gaggaacaac caaggactgg tttttgatat ctcagcatct ttcatcaagt aaccaatcaa
    31321 tccatagcca agagctgtca ggaccattgg actcaccgca tgtaagattt tgtcccaaaa
    31381 agagatgata ctgatcaaat gcatccctgt gcctaaaaag acagagatga acaagaaaaa
    31441 ccagtaaaac aaaacgattg ctgctggtat tttaagtttg aaaactttca aaatgacttg
    31501 tggcatgaaa atcaatgcaa tccctaataa agattccacg ataaatgtga ttccttgaga
    31561 agtcgaatat ttttgtgtga taaattcata aaaattatag cagacaacga atacaccaaa
    31621 agcaagtaaa gctatttgca cctttttgat ttctttaatc actgaaagtc cctccatcta
    31681 aaaatctttt tacttctgaa agcaactcaa tttctgaaga aaccactttt ccgttcaatt
    31741 tgatcaaacc tattgtatat aagttcaggt agtgaaattg attttcagct gtttcttgta
    31801 gtgcagcgat ttttttcggg tgggttccgc cttgctgtcg agtatcagta tataagccga
    31861 tcactgggat gcctttcgca taagccacac cgatttccga tgctaccccg gcatcgatcg
    31921 tcagcccatc tagtaaagca atcattaaat cactagccaa cactttttct gtgtcagcaa
    31981 gagcaatcat tcgactgtct gcataagcag ttttgtcatt gattgcttca ttttcttgag
    32041 gaagatagat cgaaagctca gaagagagct ctctgatttc tttaactaac tgttggttat
    32101 ataacaaatc acttttagca aacattggtg cggcaaaata aattttcatc taaacatcat
    32161 cctttttatc aaaaataatc gctaaagtaa gcttccatgt ttggaatgat acgctctagt
    32221 gacttcagtg tttcttcatc tgtttctaac cgttcgattc ttgccaaata agaagcacgg
    32281 cgataattca tcatcaagca agtcaatgtt tggatatcca gtcgaacgga ttttcctata
    32341 ggttcattta agacacggac ttgtccctgt tcatcccatg ttaaagcgaa gacaccatta
    32401 ttccaaggag cgacaggatc ttcaatgatg aaatgaaaag catcagctgt tccaacaaac
    32461 ggaaaccgtt gaaggaattc ttttacatca acgatccgag ccataaaata tggttcgatc
    32521 tgctctttga tctgactatc ttcaatcaaa aatgctaaag gctcattttt ataaatatct
    32581 ccatgtaccc agtagatcat ggaaaaatgt gcggaaataa agttccataa gccatttcga
    32641 gcttcttgat caagatagaa catttctttt acgtgaaata tttcttcagc tacccagtag
    32701 aacagaacac ctcttggttc atggttgcta tcgtagtaga cagcggctgt gcgctcatct
    32761 tcattttcga aacgccaata ctcttcccaa tgaaaatcac tgcggaataa agcaccatgg
    32821 ttttgttggg caaatttgtc ataaacggaa aatacgtctg gatgatcaac tggtaatcgc
    32881 tcaaccatac cacttactgg gatttgttta ggtagctgtg tatctctgat tttaaaggaa
    32941 agtttatcag acatgatttc ccatccttta cgccgatagt aggggatact gtaaggatac
    33001 aaataagaga tccattgctt attcttgcgc atattatcca atgcaacgat aattagatct
    33061 tgcatcaatc catggttagc atattctgga taagttccaa ctccagtcac accacccatt
    33121 ttataacgtg caccgtgaat attgacttca caaggataga tagcgatttg agagatcagt
    33181 ttattttcgt ggaaccatcc gaacactttc gatacttcca aaatcggttt tttggaacgg
    33241 ataaaagctc gtttattctc aaacccgctt tcctcgatgt ctgcttcagt cacttggaac
    33301 acataggaaa gcaattcatt gaattgatcg atatgttctt gagtgaccgg ttttaattca
    33361 agattttctc taaaatcttt ttgatccatt ttttcatctc catttattag cttgataaca
    33421 gtatagcaaa attctacaaa aaaaacttct atagctgact aattaaaaac tctttaaatt
    33481 actgcttttc gttggtataa tggaaagtgc tgattatatg aaaagaggag acgctatgga
    33541 tataaagaaa atgaaagaac gccaagagca gattcgtaat ttttcgatca tcgctcatat
    33601 cgaccatggg aaatctacat tggccgatcg tattttagaa atgacgcaca ctgtgacgtc
    33661 tcgcgaaatg caagatcagc tgttagactc gatggatttg gaacgtgaac gtggaatcac
    33721 gattaaatta aatgctgtag aactcaatta cacagcgaaa aatggagaaa catatatctt
    33781 tcacttgatt gacaccccag ggcacgtcga cttcacctat gaagtctctc gaagccttgc
    33841 tgcctgtgag ggtgccgttt tagtggtcga tgcagcacaa ggaatcgaag cacaaacatt
    33901 ggccaatgtt tatttagcgt tagacaatga tttggagatc ctgccagtca tcaataaaat
    33961 cgacctaccc gcagcagatc ccgaacgtgt ccgtcaagaa atcgaagacg taatcggaat
    34021 cgatgctagt gaagctgtat tagccagtgc caaatcaggg attgggattg aagatattct
    34081 cgagcagatc gtggaatatg ttcctgcacc aagtggagac ttagatgcac cgctaaaagc
    34141 tttgatcttt gactctattt atgatagtta ccgcggtgtt gttctaaatg tccggatcac
    34201 ggacggtatg gtcaaacccg gagacaaaat caaactgatg agtaatggca aaacatttga
    34261 tgttacagag gtcggggtct tctcgccaaa agcagttgct agagactttt tgatggtcgg
    34321 tgatgtcggt tatatcacag caagtatcaa aactgtccaa gatacacgag taggggatac
    34381 agtaacgtta gcagacaatc ctgccgctga agctttacca ggttaccgaa aaatgaatcc
    34441 gatggtttat tgtggtcttt atccaattga tacttctcgt tacaacgatt tgcgggaagc
    34501 tttagaaaaa ctgcaattga atgatgctgc tttacaattc gaaccagaaa cctctcaagc
    34561 attaggtttt gggttccgct gtggattcct cggacttctt catatggatg tcgtccaaga
    34621 acgcttggaa cgggaattca atctagaatt gatcacgact gcaccatccg ttatttacca
    34681 tgttaataaa acggatggta cgactgctac agtagataac ccggcagatt ttcctgaacc
    34741 tgtaacgatt caggatgtag aagaaccatt cgtcaaagca cagatcatgg tcccaaatga
    34801 ttttgtcggt gcagtaatgg aactttctca acgaaaacgg ggagaattca ttacgatgga
    34861 ttatttagat gattaccgag taaatgtcgt ctataatatt ccgctttctg aaattgtctt
    34921 tgactttttc gacaaattga aatcaagcac gaaaggctat gcctcattgg attatgaaat
    34981 gtctggttat caaaaaagca agttagtgaa gatggacatc ttgctgaatg gagaaaaagt
    35041 cgatgcatta agctttatcg ttcaccgaga ctttgcctat gaacgtggaa aagcaatcgt
    35101 tgaaaaactg aaaaaactaa tcccacgcca acaatttgag gtgccaatcc aagcagctat
    35161 tggacaaaaa atcgttgccc gttcagacat caaagccttg cgtaaaaacg tcttggctaa
    35221 atgttatggt ggagatgttt ctcgtaaacg taaactctta gagaaacaaa aagaagggaa
    35281 gaagcggatg aaacaaatcg gctccgtcga agttccgcaa gaagccttca tggccgttct
    35341 gaaaatggac gaggacgaac cgaagaaata gcaagggttt gtttgaaaac agtgtaaaaa
    35401 ataaaccatg tttacatgga tttgccaccg gtttgccacc ggtggttttt ttcggtggca
    35461 aaaatcaaga attctttcta agattttcca tgatatcgac cgtttcattt ctcatcttat
    35521 ctgttacatg cgagtaagta tccatcgtaa ttgaaattct gctgtggccc aatcgttcag
    35581 agatttcttt catttttgcg ccattttcga gaagaagtgt agcatgagta tgtctgagag
    35641 aatggaagtt aaaagagagg gagagtgcat tcgatatcct cctagtattc catttcacta
    35701 cacttggcgt aactagctca ccgtcttcct tcgtacatac tgcatttgaa tcaatgtaga
    35761 gctttccata cttcattcga ttttctaatt gttgtttctt atgttttttc agaattgcta
    35821 gcaaggtttg tccaataaaa atcgttcgat tggaactgct tgtctttggc gtaccatata
    35881 cccatgcgcc gtcattcttt accatttgtt tctctacagt aattgttcca tttgaaaaat
    35941 cgacatcatc ccacgtcaga ccacaaactt cgccaacgcg cattcccgta taaaatccaa
    36001 tattcaaagg aatatagaaa ggatgtcctt caggagtaat ttctagcata tgatcaaagt
    36061 cctcaagaga aatgattttt agatcttttt tagtcgttgg tcgtgcttca tattttggta
    36121 tttttacata cagcatagga ttttgcttga ttaatcccca aggataaacc gccatattca
    36181 gcgcattctt aaggacagag tgagtaatag tcattgtttt cttcgagtaa ccctttttaa
    36241 attcagcatt gatgaaattt tgtaaaagag caggggagag atccgtaagt tttttctttc
    36301 ctaaataacc gtttatatga tttttgatgg taaatcggta gttttcatag gtattgtatt
    36361 ttagatttag tttaacgtat tcctccatcc aaaaatcaag gtattgtttt actcgagtat
    36421 ccgtacctaa aaagtattgt cctgtttcgt caatatctga taaaactttt cgtaaagcag
    36481 cttcggcctc tggtcgggtg tctccgccaa ctttctccac tttttttctt gagccatcat
    36541 cattgatatc ttcgccgttt gtataattaa gcgagacaaa taaaaaagcc atttatgtta
    36601 cactc
//
LOCUS       DADVXM010000018        36567 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.019, whole genome shotgun sequence.
ACCESSION   DADVXM010000018 DADVXM010000000
VERSION     DADVXM010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.019"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(25..1521)
                     /gene="lysS"
                     /locus_tag="KB927_001015"
     CDS             complement(25..1521)
                     /gene="lysS"
                     /locus_tag="KB927_001015"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBB6839949.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="KB927_001016"
     CDS             complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="KB927_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBB6839950.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="KB927_001017"
     CDS             complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="KB927_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBB6839951.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3741..5852)
                     /gene="ftsH"
                     /locus_tag="KB927_001018"
     CDS             complement(3741..5852)
                     /gene="ftsH"
                     /locus_tag="KB927_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBB6839952.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="KB927_001019"
     CDS             complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="KB927_001019"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBB6839953.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="KB927_001020"
     CDS             complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="KB927_001020"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBB6839954.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8052..8522)
                     /locus_tag="KB927_001021"
     CDS             complement(8052..8522)
                     /locus_tag="KB927_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBB6839955.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8568..8993)
                     /locus_tag="KB927_001022"
     CDS             complement(8568..8993)
                     /locus_tag="KB927_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBB6839956.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9060..9329)
                     /locus_tag="KB927_001023"
     CDS             complement(9060..9329)
                     /locus_tag="KB927_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBB6839957.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9340..10935)
                     /locus_tag="KB927_001024"
     CDS             complement(9340..10935)
                     /locus_tag="KB927_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6839958.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="KB927_001025"
     CDS             complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="KB927_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBB6839959.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14488..15048)
                     /locus_tag="KB927_001026"
     CDS             complement(14488..15048)
                     /locus_tag="KB927_001026"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBB6839960.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15401..16375
                     /locus_tag="KB927_001027"
     CDS             15401..16375
                     /locus_tag="KB927_001027"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBB6839961.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16545..17945
                     /locus_tag="KB927_001028"
     CDS             16545..17945
                     /locus_tag="KB927_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBB6839962.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18023..18745)
                     /locus_tag="KB927_001029"
     CDS             complement(18023..18745)
                     /locus_tag="KB927_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6839963.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18824..19330)
                     /locus_tag="KB927_001030"
     CDS             complement(18824..19330)
                     /locus_tag="KB927_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBB6839964.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19453..21252
                     /locus_tag="KB927_001031"
     CDS             19453..21252
                     /locus_tag="KB927_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBB6839965.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21320..22894)
                     /locus_tag="KB927_001032"
     CDS             complement(21320..22894)
                     /locus_tag="KB927_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6839966.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="KB927_001033"
     CDS             complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="KB927_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBB6839967.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="KB927_001034"
     CDS             complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="KB927_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBB6839968.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24671..25309)
                     /locus_tag="KB927_001035"
     CDS             complement(24671..25309)
                     /locus_tag="KB927_001035"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBB6839969.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25310..25960)
                     /locus_tag="KB927_001036"
     CDS             complement(25310..25960)
                     /locus_tag="KB927_001036"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBB6839970.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="KB927_001037"
     CDS             complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="KB927_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBB6839971.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="KB927_001038"
     CDS             complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="KB927_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBB6839972.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29103..29843)
                     /locus_tag="KB927_001039"
     CDS             complement(29103..29843)
                     /locus_tag="KB927_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBB6839973.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="KB927_001040"
     CDS             complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="KB927_001040"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBB6839974.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31214..32152)
                     /locus_tag="KB927_001041"
     CDS             complement(31214..32152)
                     /locus_tag="KB927_001041"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBB6839975.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32145..32636)
                     /gene="def"
                     /locus_tag="KB927_001042"
     CDS             complement(32145..32636)
                     /gene="def"
                     /locus_tag="KB927_001042"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBB6839976.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32651..35059)
                     /gene="priA"
                     /locus_tag="KB927_001043"
     CDS             complement(32651..35059)
                     /gene="priA"
                     /locus_tag="KB927_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBB6839977.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35312..35617)
                     /locus_tag="KB927_001044"
     CDS             complement(35312..35617)
                     /locus_tag="KB927_001044"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6839978.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="KB927_001045"
     CDS             complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="KB927_001045"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBB6839979.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9885 a         7988 c         6706 g        11988 t
ORIGIN      
        1 attccttaga cagcttttat tcgattatct cattgttggg aatagcaaaa catcccgaat
       61 tgattgtgca tcagttagca acattactaa tctgtcgatc ccgatgccta gaccaccagt
      121 tggcggcata ccgtattcta aggcttccaa gaagtcttcg tctacaccgt gagcttcgtc
      181 atttcctagt tcacgttctt tttcttgcgc ttcgaatctt tctctttgat caattggatc
      241 gttcagttct gtaaaggcat tagcaaattc gcgccccact atgaatagtt cgaatcgatc
      301 tgtgaatcga ggatcttctg gatttttctt cgctaaaggc gaaacttcga ctggatgtcc
      361 gtatacaaac gtcggttgtg tcaatgtttc ttcaacaaat gtttcaaaga attcattgat
      421 aacatgtccg acacccatag cttcggttac ttctacattg tgtttttcgg ctaaagctaa
      481 tgcttcttcc aatgtcattt cttgccagaa gtctacacca gtttgttctt tgattgcatc
      541 taccatatgg atgcgtttaa agtcactttc taagtcgaca gcttgtccat catatgtgat
      601 ttttgctgtt cctagtactt tttcagctgc gttacggata ataccttctg tcagattcat
      661 tacatcattg aaatcagtat atgctgtgta tgcttctaac atcgtaaatt ctggattatg
      721 tgtagtatca attccttcat tacggaaaac gcggccgatt tcataaactt tttccattcc
      781 gccaacaatt agtcgtttta aatgaagttc tagcgcaata cgcaaatata aatcaatgtc
      841 cagtgcatta tgatgcgtga taaatgggcg tgcggcagct ccacctgcct cattgtgcaa
      901 tactggtgtt tctacttcaa tatagccatt gccatctaaa tagcgacgga tttcgctgat
      961 aatttggctt cgtttcataa atcggtcaaa gctttcgcga ttactgatta aatccaagta
     1021 gcgttgtctg tagcgttgtt caatattcgt taagccatgg tatttatctg gcagtggacg
     1081 aagtgctttt gacaaaatcg tgatttctga agctttgata gaaacttcgc ctgtgtctgt
     1141 tttcatgatt tgtccagtta caccaaagaa atctccaagg tctgcatgtt tgaatacttc
     1201 ataggcctca tcacctactt ggtcttttct tacataaatt tgaatttggc cttcacgatc
     1261 ttgtagatgc gcaaatccag ttttcccttt tcctcggcga gtcatcatac gaccagctac
     1321 actagcggtc aatcccattt ctgctagttc ttcttttgtt cttggatcaa atagttcatg
     1381 caattcttct gagttgtgcg tgcgttcaaa tcgttttcca aatggatcga ttccatcttc
     1441 acgcaattgt tccatttttt gacgacgtac aagcatttga tcatttaaat cttctacttg
     1501 atgttgttgt tcctgtgtca caaaagttcc tccattctca tgttaatctc tttcctataa
     1561 tgccaatgaa acacaaaaaa agcaagccga acttggaatt tcggcttgaa aattcacgaa
     1621 aaacttagaa atcacaacgt ttgtttcaat agtacttttt ccgctttttc tacaaattga
     1681 tccagcaggt cattgatttc ttgctgtttt tctgtctgat tgattgctac tttcactttc
     1741 gctgctcgag gaatcccttt taaataataa gccgcatgtg ttctgaattc tctacaagct
     1801 actttttctc ctttgagatc tgctaagcgt tgtaaatgaa gtttagctgt agcaattttt
     1861 tcggctggtg ttggttcagg aatcagttct cctgtttcga gataatgctg tgtgcggtga
     1921 atcatccatg gattgcccag cgctgcacga ccaatcatca caccgtctgc accgacatag
     1981 tcaagcatcc attttgcatc ttctggcgtt ttgacatccc cgttccccat aaatgggatc
     2041 gtcaaatgtt ttttcacttc tttcaatact tcccagtccg cttttccttc atacatctga
     2101 acccgtgtac gtccatgcat agcgatggca cttgctccag ctgattgtgc tgctaatgca
     2161 ttttctacag caaagacgtg ctcttcatcc caaccaatac gcatcttgat tgttactggg
     2221 atatttactg ctgaagaaac agcttggacc atttcgtata ctttctcagg atctaaaagc
     2281 cattttgctc ctgcttctgc tttgattact ttatttactg gacagcccat attgatatct
     2341 attatatcgg cagctgtgtt ttcttcgaca aattgagcag cttcaactag actatcttta
     2401 tttccgccaa atatctgtaa acttaatgga tgttctgttt cttcaatgtg gagcatctct
     2461 aaagtttttt tgtttctgaa atgaatacct tggtcactga tcatttcaca tacgactaag
     2521 cccgcaccaa attctttgac agtgactcga aatgctgaat ttgttattcc agccatcggt
     2581 gcaacaacga cacgattagg gatttccaca ttgccaattt tccatgtgtg ttccacttaa
     2641 atccctccta aggcttcttt cttcaatcca tctaattctt cttcgctata cttgtatttg
     2701 ttattacaga aagaacaaac cgcttctgca ccgtgatctt cgtctatcat tgcttggatt
     2761 tcttctgcac ctaacgcgat aattgcttct gcaaattttt cttttgaaca gtcacatttg
     2821 aattgaacag gcattttttc caaaatgttc aattcttctg taccaagcaa tcctttcaat
     2881 atttcttctg gtgtctgtcc ttcatctaag agggtagaga ttcttggtgt cgtttttaat
     2941 tgttcttcga tcttgctgat tgtttcttca tcggcacctg gcatgatttg gatcatgaat
     3001 cctcccgccg tcttgatgct gtcgtcagta ttgaccaata cactcagtcc aacagctgaa
     3061 gggatttgtt ctgagatagc aagatagtaa gtaaaatctt cagcgatttc tccagaaaca
     3121 atcggcgttt gcccagaaaa aggttctttt aatcctaagt cttttgtgac agtaaacatt
     3181 ccttgtgttc caactgctcc ccgcacatcg attttacctt cactatttag aggaagactg
     3241 agatgcggat ttttgatgta acctttcaca tctccctttc catttgcatc tactacaatt
     3301 cctgttgctg gaccatcgcc ttggattcga acagttagtt tgtcttctcc tttgagcgtc
     3361 gcaccaagta gcagactacc gaccaatgtc cgtcccaaag cagctgagga ggtgtgccaa
     3421 gtatcatgac gtctttgtgc ctccgctacg gtatttgttg cttgaacggc gtatgctcgg
     3481 acgaatccgt cgtgagcaag tgccttaacc aaataatctt tcatttgtta tgtactcctt
     3541 tttccgtttt taaactcata gtgaatcata ctagcaacta ctgctttttt caactttgga
     3601 atgcttcttt taaaaataat tcagaatcat ctagaaaaca ggacatcacc ctatttacaa
     3661 cttaaataaa gaaatctccc gaaaaccggt ttttgttccg gttttcggga gtcatatcag
     3721 atcaattgac ctatattttt ttatttgtat tgatcgtctg aatgattatc ttctgattgt
     3781 tgagaatctg aatcatgttc tgctttattt tcctcattca gttcatgttt tgcttcttca
     3841 aaatcacgtt tttcttccgc ttgtttttca gcgtcttttt cttccaaagc acgttttgct
     3901 tcttcaaaag ttttcgcttc tttttcgctt ggataatcat ttgactcagt accttcaggc
     3961 atcacaccgt gttcaaacaa tgacttgatt gctttggcat ccaatgtttc gaattccaaa
     4021 agtttttcag caatcagttt atgctgtgca cgatgagctt cgatgatttc tcgagcttta
     4081 tcatgagctt ccatcaagat ttttcgtact tcttgatcaa tctcgaaagc gacttgttcc
     4141 gagtaagctt ttgtttgacc atagtcgcgg ccaacaaaca cttgatggtt tccttcatat
     4201 tgaacaggac ctaaacgatc actcattcca tattctgtta ccatgcttcg tgctagagct
     4261 gtcgcttgct caaagtcatt ggaagcacca gttgattgga cattgaagat gatttcttca
     4321 gctgtacgtc caccaagtaa gcctacgatt tgttcaaaca tatcttcttt cgtcatcaag
     4381 aactgatctt cttttggtaa agcgatcata tatccgccgg cgcgtccgcg agggatgatc
     4441 gttactttgt ggacgacccg agcgcgactc aatactaatc cgacaatcgt atgaccagct
     4501 tcgtgataag caaccatttc gcgttctttt ttgctgatta cgcgatcttt tttagctgga
     4561 cctgcaatca cgcgatcttc cgcttcatcg atatcagaag catcgatttt ctttttattt
     4621 cttctagcag ctactaacgc tgcttcattc aagacatttt ctaaatctgc tccggcaaaa
     4681 cctggtgtct gttgagccac aactttcaag tcaacgtcat ctgccatcgg tttattccgt
     4741 gcatggactc gcaagattgc ttcacgacct tttacatctg gacgtccaac taaaatctgg
     4801 cggtcaaaac ggcctggacg tagtaacgct gggtctagta catcagaacg gttggttgca
     4861 gcaatgacga ttactccttc atttccgtcg aagccatcca tttctacaag caattggttc
     4921 aatgtttgtt cgcgttcatc atgtccgccg cccataccgg caccacgttg acgacctacc
     4981 gcatcaattt catcaatgaa aatgatagct ggtgcgtttt tcttcgctgt ttcaaacaaa
     5041 tcacgaacac gacttgctcc aacaccgaca aacatttcta cgaaatcaga acccgagatc
     5101 gagtaaaacg gtactccagc ttctccggca acagcttttg ctaataaggt tttacctgtt
     5161 cctggaggtc cttctaaaag tacacctgcc gggatacggg cacctaattc aacaaatcgg
     5221 cgaggatctt tcagaaattc aacaacttca actagttctt gtttttcttc ttccgcaccc
     5281 gctacatcag aaaaacgtac gcgattagct tttttgtctg cttctttggc ttttgattta
     5341 ccaaagttca tgacacggcc gccaccgcca ccgccgccgc cttgttgtcc catcatcatg
     5401 taaaagaaaa agatgatgat tacgattggc aagaagctaa gcaataggga aacccatata
     5461 ccgctgcttg attcttcttt tactgttgta gcaactttgt tttcttttgc cagttctgtt
     5521 acttggctca atgttgtatc atttggcaaa atgattgttg tgaaatgggt agtagtcgta
     5581 tctgttgaac ctaagatagc taacccaccg ctgttagcga cggtctgctg ttctttgtat
     5641 tcaccagtga tcttatatac accatttgca ggctgcactt caaattcttt gatcttgcct
     5701 gcttgtagtt gttctgtgaa ttttgagtac tcgatatctg acgatcgctg gccgttatta
     5761 ccaaaaatga aataaacgac cattaccatc gctaagatta cgaggacata atacaaggca
     5821 tttttcatca tgccgttgtt ctttttgttc atagttgccc tccctaagcg tcaatttaat
     5881 ttaacagttt tttatcaatc ctgaccattc tattgtacca taatttaatt gagatacagc
     5941 attaatttga ttgataaaca ctaggtttca atacaccgat gtacggaagg ttacgatatg
     6001 cttctgcata atccaagcca taaccgacca caaattcatt tggtacgttg aagccaacat
     6061 aatctgcttc gatatttact actcttcctt caggtttgtc aagtagtgta acaattttga
     6121 ctgattttgc tttgcggtat ttgaaaagat ccactaaata agcaagtgtt cttccgctgt
     6181 caatgatatc ttcaacgatc aacagatcgc gaccttctac attcgtatct aagtctttga
     6241 cgatttttac ttcccctgac gagactgttg cattcccgta gcttgaaaca tccatgaaat
     6301 ccaattccaa atacgtatcg atagaacgaa cgatatctgc catgaatggt accgctcctt
     6361 ttaagacacc tactactagg ggattggtgt tttggtaaat ttctgttaac tctttgccta
     6421 gttctttgca acgaacttgt atctcttctt gtgagatcaa aattctctca atatcctttt
     6481 ccaacatcag gttctccttc caattgcttc tttttgatat ttgtaaagaa gtatgtagtg
     6541 tattttatca gtttcttcac gaatactcaa atatgaaaag gcaaaaggta tcaagctata
     6601 tatatttctt ttggcatctg taatgatcca agcatgctgc ctttgtgaat taggtacttt
     6661 ctgatcgata aaatatctag atactttttt tgtgagattc tctgttaatt taatgcggtc
     6721 tcctgctttt cttttttcga catacagttg cacatcagca ggaatccaaa tgtcatgaga
     6781 aaatagagac catgaatctg ttgctttgat gtcccctgca ttttcaggtt tgaccagacc
     6841 aatccattct gtttcattca aatatattcc ttgttctgga atcagcaaca agcgctggtc
     6901 ttctgtctgg ctagttgctt gtttttcttt tttagagagt acaacaaaat gatactctct
     6961 tttcagtatc caattattgc caatactgag ttgccattgg ctttttttct gttgccactg
     7021 gtctaaaatc gactccattt gttgttcttt caaaataatt cctgtttttg agaatgcttt
     7081 gtcgaaaaag gagtaaaaaa aatagtatcg ttcagcatct gtcatttctt caatcatttc
     7141 tgcagaaaat cgaaattgtt cctcccactg ttcgacttcc ttttcgatca actgtcccat
     7201 atatttttga atgacttggt ctgcccattg gatctgttgc gaaaattgct ggaaatgtct
     7261 caacgcctgt gtattttctt gtttcaattg aggaactacc aaatgacgaa gccgatttct
     7321 ctggatatct aacaattggt ttgtctgatc ctcaaagtaa acaagctgcg attccgctgc
     7381 ataagtatat aggtcttctt tgctaaaact cagcaacgga cgaatcagtc tgcccgtagc
     7441 aaatggttgt acttctttga ttccagaaaa agtatttaac tgtcccccac gaacgatttt
     7501 cattaacacc gtctcgattt gatcatctcc gtgatgagca gtcatcaacg tgtcatattg
     7561 tccttcttcc atcacgcgag tgaattcttg ataacgaaag ttacgagctt ctgtttctat
     7621 ggcggatttg gctggatctt cccaaatact tacatataaa gggagattct tctcttcaca
     7681 atatgagcga agataggcag cttcttctgc tgattcttct cttaattggt gattgatgtg
     7741 gacgatacct aaagaaaaac cgatttggcg ttgcacttgt aaaagtaaat ggagcaaaac
     7801 catcgaatca acaccacctg ataccgctgc taaaattctc gatccttgtt gccagaatcc
     7861 ttgttcattc ccgtgccgaa taaatgactg ctgtaatagc ggtgcttttt tcccgccttt
     7921 ttcaacgttc atcctttcca caccctttct tcctaaaaaa aagagagcgg gaaaacgtct
     7981 aaaacgacaa ttaacctgcc ctctgttgat actatgaccc aaatagtcgc actatcatta
     8041 tttgcggctt tttagctgcg acgtccgcca cggccaccgc gctttccttc tgtgtttcgc
     8101 ttcaatgaag ataagcggtc atcgctatct ttcaaaaatg aactcatcaa tgaatcgaag
     8161 tcttcttttt gagctgaagg ttgactgcga gaaaaagatt ttttctgtgc tggacgattt
     8221 cggttgtcac ggggatcttt ttgttgatat tttttaggac ggctttcttc tccagattca
     8281 gcaggttgtt cctgcgcttt ccggatagat agtccgattt ttccatcatc atttactgaa
     8341 ataactttaa ctgttacttc atctcctaca cttaaaacat catggatgtc ttttacatag
     8401 ccatttgaca cttcgctaat atgaactaga cccgtttttc cagcacctag atcaataaac
     8461 gcaccaaaat ttgtgattcc tgatactttt ccttgcagtt ttgctcctac ctcgattgac
     8521 ataaaaaaaa tgttcctcct aattatttcc cttttttata ttcctgctta ttttgcagtt
     8581 gtagaactag ttgattgatc tgtttcattt gtcgagctgt ctgtatttga ttctaatata
     8641 ggataaactt tttcaccgtc ttttgagtaa aagaatttgc ttctggcaag tttagctaca
     8701 tactcatcat ctttcagcaa tgaaacatct tggtgcagct gatcaacgtc tgcgttgact
     8761 tctttcattt cagtatttgc ttcgactctc aattcgttca attgatgcat cctttgcatg
     8821 tcatggaaaa tctgcacacc tattatcgcg aaaatgacca aagcaccaac aaaaattgca
     8881 gccagtctgc gtcttcgaaa aatcagttga cgttgttgtt gctgaaattc agcatacttt
     8941 ttctttgcat attccgtatc tagcgcagcg attttattgc tttttttcgt cacttggatt
     9001 cgctccaatc tttttgattg tctttttcat tataccaata tcgtgaaagc ttgtctaatc
     9061 tatttctcta gtgtttctgt gcgattttca gaaataattt cgtacatttt ttgtgcatct
     9121 tcttttttgg ttgattcatg taattccgta attttcactt ccaacgtttt gttgccaaac
     9181 tggactttca aaatatcgcc tactttgaca tcactggaag atttcgccaa tttaccgttg
     9241 atttgaattc ttcctttatc agctacttct tttgctactg atcgtctttt gatgattcgg
     9301 gaaattttta aaaatttatc taatcgcata tcttattcct cactttttaa tttttttatt
     9361 taatcgcagg attttcttac caaaaggcaa cattagccat tctcgtactg taaacagacg
     9421 aagacgaatc actgcataaa tgaacacaga agccccgatc ccaactccta tcacgctgac
     9481 aaaaaaagca gtggaacgat gagttacagg accaaatact atattcaata caccataata
     9541 cagcagcagt actactgtca tacaaagaag gctgaacatc aacttccgtc caaaatgccg
     9601 ttctttccaa aaagcattta gctcttttgt ttcaattcga acaaaatacc aaagcgtcac
     9661 acctaatcct aaaagggtag acaggcttgc acctgctgtt cctaataaac cggtcagaaa
     9721 agaagtagtc aatcctttta ccaatagtcc ccatcctgcg ccttttaaag aagggcgaaa
     9781 cgagttcttg ctttgagcaa tactttgata agcttggatg actgcagtga aagcaatgga
     9841 aaaaacaaat aatacaagcg ctgcatttcc cgcataatct ttaaacaacg cataattgat
     9901 ataagggagc agcaaggcta atcccaaaga cgcagctaat gctaaagcgg tcgtcaatct
     9961 aagatagatt ttggctgtct gtaaaaactg acgatagatc cggttggtca aatgacgagt
    10021 caacgcaggc aggaatgtcg cacttaatgc agtggcaatc actaaaccta attgtactaa
    10081 aggctgacct cgatcataga ccccttttgc tatcttcgca ccgtattctg acagtccgta
    10141 aacttccaaa gcatttttta caaagaaaga gtcgatcagc tggaaaaaga taagcaatcc
    10201 actataaatc gaaaccagtc cgccttctac cagaaaacgc cggatcaagg gctttgacgg
    10261 ctgtttgaac aatggaaacc gtcggaagct taacgctcct ccatgaatct tttgttcata
    10321 gtagtgaagg atcccatatg cgcataaacc gccaaaaaca gctccactca ttgctgccgt
    10381 ccctgtttgg tacaccgtcc atccaagctt tctaaaagca aacgcactac agacaatcac
    10441 aaaaacacga acgaactgct caactacttg agaaacagca gttggttcca tcaagaatct
    10501 tccttggaaa ttccctcgat aaaaagatag accaggcatc agcaaaaagg taaaggaaac
    10561 tacttggatc agcggtttca attgtatgtc tcccatcatc caagcaatcc agctgctaaa
    10621 tgcaaagaca aacaaccaca aaaagacacc tgtccaaaat actaagggat aaagattttg
    10681 caaagcttgc tttcgctcga aaggattctt tctttctgca acgtactttg atatgaactg
    10741 cggaagaccg gataaagcta aagtcattgc tatcccataa attggataaa cttgctgata
    10801 aacataaaaa ccttcgtcgc cgactaagtt ttggagggga attcggtaaa gggcacttaa
    10861 tacttttgct atgaaagaag caatcgtcaa tacaaatgct ccttgcatga cgcgccgcat
    10921 ttctttatga tccaaatcat tgctccttcc tacgctgaca gatatttttg ctcacgcaac
    10981 gctttgacaa acttttggat ttcctgaagc catactgctt cttccatttg gttggggatc
    11041 gtcaagcgta tcaccatctg ttctttttca acgcctagac tggcttttag ttttgtcgct
    11101 gtcagtgctt cgaataactg ttccacacta tagcgttttg ttccaacttt acttagagta
    11161 aagactatat gcgcctcctg tttccttatc gtttctagga gcgctcgatc gccatccatt
    11221 ttgatctgcc caattgtcaa gagatgtgct acttcttctg gatattctcc aaaacggtcg
    11281 agcagatcat cttctagttc atctagcatt tcttgcgaat caagttcacg aattcgttta
    11341 tagatctcga ttttctgccg ttgatctgcc acgtatgttt caggtagata cgcatcgaca
    11401 ccgaggtcga tctcaacagt ggtcttctcc acttgactat tctttccttg tttacgagaa
    11461 acagcttcgc ttagcatttg agaatacata tcgaaaccga ctgcatcaat aaatccatgc
    11521 tgctgagcac ctaagagatt acctgcaccg cgaatggaaa gatcccgcat cgcaatcttg
    11581 aatccagatc ccagttctgt aaaatctttg attgcctgaa gacgtttttc actgacttcg
    11641 ttaaggatct tctgctgctc atacataaag taagcatatg cgacacggct gcttcttcct
    11701 acccgccctc gcaattggta taacgtggat aatcccatat aatcagcgtt ctcaacgaac
    11761 aacgtatttg cgttcgggat atctactcct gtttcaatga tggttgtagt gacaagaaca
    11821 tcatattgac cttcaataaa ttcaaaaagc gtattttcta attgcgcctc tgtcatttgc
    11881 ccatgagcat aaccgatccg tgcttccgga acgagttctt ggatttcttc tactttttgt
    11941 tcgatcgttt ctacccgatt atataaatag aatacttgtc cacctcgtcc catttctcga
    12001 tggattgctt cgcgaatagc cccaggattt ttttccataa catacgtttg gatcggataa
    12061 cgattcgcag gcggtgtttc gattactgaa agatcccgca cgcctaacat cgacatatgc
    12121 aaagttctcg gaatcggtgt tgcagtcaga gtcaaaacat ccacttgtgc acgtaactgt
    12181 ttcaatcgtt ccttatgttt tacaccaaaa cgttgttctt cgtcaatgat cagtagaccc
    12241 aaatcgctaa attcaatatc ttttgacaaa attcggtggg ttcctacaac aatatcaact
    12301 tgacctgtac gcagttgttc gatggtttct ttttgttgct ttcttgttct gaaacgactt
    12361 aatagcccga tatttacggg gaaaccttca aatctttcca gcatcgtttc atagtgctgc
    12421 tgtgccaaga tcgttgttgg aactaaaaag gctacttgtt tgctttcctt tatcgcttta
    12481 aaggccgctc gaagcgctac ttctgttttc ccataaccaa catcacctac gagtagtcga
    12541 tccattggtt tttctttttc catatcccgt ttgatctccg ctgcacttct caactggtca
    12601 tcagtttcag agtaggggaa ggcattttcg aattcttttt ggtaggcgtc atcaggtcca
    12661 aaagcatatc ctttttctga ctctcttgcg gcatataatt tgattagatc gtcagcgata
    12721 tcctcgattt ttgaagagac ttttcgcttg gttttcgtcc attcacttcc gcctagctta
    12781 ttgatgcgag gcgctttggc ttcagaggcg acatattttt ggatcagatt cagttgagta
    12841 acaggaataa acagtttgtc gtcgttttga tacaaaatag tcatatagtc ttggtgaacg
    12901 ccatctactt ctagcgtttc catcccaatg tatttcccga taccatgatt ggcatggaca
    12961 acgtaatctc ctgcttttaa ctcattatag cttttcaatc gctctgcgtt tgttactgtt
    13021 tgacgtctcg tttgtttttt cgtcgttttt tggaaaattt ctttttctgt gatagctact
    13081 attttttctt gaggaagttc aaaaccagcc tgcaaagctc cttcaactaa ttgtacctgt
    13141 cctctgatca atgcattttt ttctgtttct actactaata tgtcttcatc tcgaagcatt
    13201 tgttctgctt tgcgtattct gtcctttgtc ggaataaaga tcacaacagt ctgtttttgc
    13261 ttgcgccaac ggtccatttc tgttttcagc aatggcattt gtccgaagaa ctgttgcatc
    13321 gtccgatatt gaaaattatg gattgcttgg aaacgaagat ttcccatccc tttttggaag
    13381 agtgagaaaa aggttgtggt gaacttttcc ttctgcacga ttttttgtat atctgctgaa
    13441 aatgtctgct cagaaaacac ccgcaattcg ctgatttttt gagtctgcca ttctgccgct
    13501 tccctttcga tttcccgatt tgtttccatg attcgctgat aatcatcaac gactagtaaa
    13561 ctatttgaag ggaaataatc caagatcgtc acagattctt ggtaaagaag atctgagtag
    13621 aattttgctt cttctgtcgg gacacctgct tgccagcttg aagtcagctg accgaagtaa
    13681 tcttgcaaaa actcgcggtc tgcttcttct gtggtcgcag caagccgttt ttctagcatt
    13741 ttttgcattt gctctattcc atgttctaga tcctctggtc cgtagacttg ttcactcgtt
    13801 ggggaaaccc agatttcttc cgttttttcg attgagcgtt gtgtttctgc ttcaaaatac
    13861 cgcatagaat ctatctctac atcaaatagt tctacacgaa caggataggt tgtcgttaac
    13921 gggtaaatat cgataatgct tcctcgaata ctgaattctc ccggttttgc gaccatctct
    13981 tctcgtacat agcccatcaa agtcaattgg cgaggaagat tttccacgtc tatctcatca
    14041 ccaatatgcc aattcaattg cgcctgtagc caagttttct tattcggcag tcgtttgtgc
    14101 aaagatgcga ctggcaacaa atagatacct gctttttttt cttgaagtgc gttaagcgtt
    14161 gcaactctct cgcctcgcgc ttctggagaa gaaaaggcca tttcagcaga aagcacttca
    14221 tccactggaa ataaatggat ctgatcttgc ggaatcacat gttgcagatc ttctgctaac
    14281 tgattcgcat aatacaaatt tggcatcaga ataatcatgt ttttatttgt tttcttaaac
    14341 gctcgagcaa atagaagtgt tttcgctgag cccgctaatc ctgtgattag ttgtctaggc
    14401 attttttctt ctaaattgct gacccattct tttacttgcg gatcttttcc gactaattga
    14461 ataatatcca ttccttttcc tccttcctca attgaatcga ttcatcgcat ccacgaacga
    14521 atgcccttct atgagatatt cgactgcttt aacagattga cacatgcttt cttctatcaa
    14581 aggctgattt tctttgctga aaggactaag cacatgctgg actactgttt ttttcccttc
    14641 tggcctgccg attcccacct tgattcgatc aaagacattc gtattcaaat gggaaataat
    14701 acttttgata ccgttatgcc cgccggcact tcccttttga cggagccgga tttttcccac
    14761 tgccagatcc aaatcatcgt agattacgac taattcctct ggataaatcc caaaataagt
    14821 cattagtggg ccgactgcac gaccagattc attcatgaat gtttgtggtt tgactaaaag
    14881 gatcttttct ccattatgaa aaaattcggc aacttctgct tcgaacggat tttttttgaa
    14941 agtagcttga tgctcgcgtg caattttatc cacgaccata aagccgatat tgtgttttgt
    15001 atattggtat ttggtacctg ggtttcctaa cccgacgatc attttcattt ttgttttcca
    15061 cctaattcta aaaagcagca caaaaggctg gactgctaat tagcggtcca gtccatcgag
    15121 cttttttctt ttttatactt gtcaatgcat agtataacac aaaacaaggc gtttcggcta
    15181 aaagagaatc gttaataaat gataaagaaa ttaaaaattt cttcaaagtt taatgaaata
    15241 attgatatat aaaaatagtg aaataacgca catgtaagct tttacatata atacaacctt
    15301 gttatctgtt atattttata gccaaatagc gtgacatggg gcttgagaaa tgttagcata
    15361 agcatgggaa aaaacaaatc aatggaagga ttgatactaa atgactgcag ctgcagaaaa
    15421 aaaagatcat caaaaagtta ttcttgttgg agacggcgcc gtaggttcta gctatgcctt
    15481 tgctctagtt actcaaaata tcgctcaaga agtaggtatt gtggatatca atactgctaa
    15541 aactgaagga gacgcaattg acttgtctca cgctttggca tttacttcac ctaaaaaaat
    15601 ctattctgct acttacgcag acgcacatga tgctgactta gttgttatta cagctggcgc
    15661 accacaaaaa ccaggtgaaa ctcgtttaga cttagtaaac aaaaacctaa aaatcaaccg
    15721 cgatgttgtc acacaaatcg ttgaatcagg atttaacggt atctttttag ttgccgctaa
    15781 cccagtagat attttgactt actcaacttg gaaattctca ggtttcccta aagaacgcgt
    15841 aatcggttca ggtacctctc ttgactcagc tcgtttccgt caagcacttg cggaattagt
    15901 tgacgttgat gcacgtaacg tccatgctta catcttaggt gaacacggag attcagaatt
    15961 cccagtttgg tcacatgcaa atgttgccgg cttgcaaatc tatgaatggg taaaaaacaa
    16021 cccagaaatc gatgaagaag ctatggttaa cctattcttt ggcgtacgtg acgctgctta
    16081 cacaattatc gagaaaaaag gcgctacttt ctatggtatc gcagtagcat tagcacgtat
    16141 cactcgtgcc atcttagatg atgaaaatgc tgttcttcct ttatcagtat tcatgaatgg
    16201 cgaatatgga ttgaacgaca tctacattgg tgcacctgct gttatcaacc gtcaaggtat
    16261 ccaaaaagta atcgaaattc ctttaagtga cagcgagcaa gaccgtatgg ctgcttctgc
    16321 taagcaatta aaagaaattc tagatgaagc ttttgctaaa ctagacgctg aataatcttt
    16381 gaacatgacg gaaaacatct attcggtgtt ttccgttttt ttattttatc acccttatgg
    16441 tttctaaatt ttttcataaa gtagagataa ccttcgtctt ttcctctaaa ttatgctatc
    16501 atgagaccgt tccaccctaa acttttactt aaggagttgt cgatatgaca agatcttcgc
    16561 atcgaaaaaa atcgaaacat gttgctttgc tttcagttct tggtgttctc ttagtgctga
    16621 tcagctttta tacctatcgc agtacatact acacaaagca ttttttgccg aatacagaaa
    16681 taaatggaat aaatgtcagc aatctaacag tcgaaaaagc aaatgaaaaa ttaaaagaag
    16741 cttattctga taaaaaactg gctattaaag aagatggaaa agtctggcag gaagtaccaa
    16801 aatccgagct cggctacaaa gatgatttca cttcggagct ttctccgatc ctaaatgaac
    16861 aaaacggatg gacttgggga atgacttatg tctcagcggc agaaaaacaa gaaatagatc
    16921 ctgtcagtca aaaccaccaa aaactagaca ctaccgttca gacattgaca actaagctga
    16981 ctgatttgaa caaagaccgg acacctacta ctgatgcaac gatcgaaaaa gcaggtgact
    17041 ctttcgttat caagcctgaa gtcaatggaa atacgatcga cgtcgatgct gcggtcaaac
    17101 aattaaaaag tgcggtaaac tctggtaaag atacaattga attgactgaa ttcaaagaaa
    17161 aaccaaaagt aacatctgaa gacagctcac tgaaagaaca actcgcatcc atgaatgcta
    17221 tcgcaaatgt aaaagctact tacagtataa acggtgagac tttccagatc ccatcaagtg
    17281 atattatgag ttggctgacc tacaatgatg gaaaagtcga tttagataca gaacaagtac
    17341 gtcaatatgt aacagattta ggcacaaagt ataacacaag tacgaatgac acaaaattta
    17401 aaagtacaaa aagaggagaa gttacggtcc cagttggcac ttacagttgg acgatccaaa
    17461 cagacagtga gacagaagca ttgaaaaaag cgattctggc aggccaagat tttactcgtt
    17521 cacccattgt gcaaggtggc acaaccgctg atcatccatt gatcgaagat acgtatatcg
    17581 aagttgatct ggagaaccag catatgtggt attacaaaga cggaaaagtg gcccttgaaa
    17641 cagatatcgt ttccggaaag ccaactacac ctacacctgc tggagtcttc tatgtttgga
    17701 ataaagaaga agatgcaact ttaaaaggaa caaatgacga tggaacacct tacgagagtc
    17761 cggtaaacta ctggatgccg attgactgga caggtgttgg tatccacgat tcagactggc
    17821 aacctgaata cggtggagac ttatggaaaa cccgcggttc acacggctgc atcaacaccc
    17881 caccaagtgt aatgaaggaa ttattcggga tggtcgaaaa aggaacgcct gtattggtct
    17941 tctaacaaaa ataatatata aaaagaaagc acccgtacga ttggtacagg tgctttcttt
    18001 ttattatcta acaatgtgct acttacattt cagcagcagt aaagacttct gaaacatcat
    18061 catcgtcttc tagcttatct actagacgtt ccaattgctc tttttgttcc tcatttaaat
    18121 caatcgtcgt ttgtggaatc atcgtcaatt ctgcttgcgc caaagtgaac tctttttcca
    18181 actcatctcg tacagcagca aaatcttctg gtgcagtata aatctcgaat acttcaggag
    18241 aagtttgcag atcttctgcc cccgcctcta atacatcctc aaacatcgtc tcttcatcaa
    18301 cagtcaaccc atcgcgttca atagcgatat atcctttgcg gtcaaacaag taactgactg
    18361 aacccgtttc tcccagtgat ccaccgtttc gagtaaaagc tactcggaca tttgtcgctg
    18421 tccgattacg gttatctgtc aatgcatgga ctaagattcc tactccaccc ggaccatatc
    18481 cttcatacgt gatttcatcg taattcgttt catctacggc actcgtagcc tttttaatcg
    18541 cccgttccac attgtcgtta ggcatatttg cagcttttgc tttgtccaca acaagccgca
    18601 aagctggatt catagatgga tcaggaccgc ctgctttagc tgccatataa atttcacgag
    18661 aaagtttctg aaagactttc cctcgttttg catcttgggc attttttctt ccttggatat
    18721 tatgccattt actatgtcct gacatgattt ttcctccctt gttcttttga gaatacactt
    18781 ctattctagt actatttcac aaaaaaacaa agccacagcc aatctataaa cgcttcttga
    18841 atgccgcaaa aagcacacat aatatcacag cagtcagagc accgatcgaa tccaacatga
    18901 catcttggaa cataggtgtt cgtccaccgg tcatcatctg atggaattcg tccaaacctg
    18961 cgtaccctgt tgctgaaagc caagcaagga tcgctgtcag ccaccaaatt tttagcttgg
    19021 ggaaaacacc taaaaacaag ctgcctccca aaataaaata ggtaccgaaa tgtgcgccct
    19081 tccttaaaaa gaactctaaa aatttggcgt agcccagatg gtcgatactc accatacttc
    19141 caccataatt aaaacgtata cccgctaatg tgtctttaaa tggctgatta ggcagccagc
    19201 tttctaatcg cgaaacttgt gattgctgtc cgtaagtttg agaagaactg taaaataaga
    19261 ttataacgac tatcagtgcg attactaaat aaatatttcc gtttttcatt tgtttttttg
    19321 aagaattcat aagtcacctc tgtattttat cttagacttt ttttgaagaa acaacaatca
    19381 ttttcataga gacttcttcc ataaaaaagt gctatactta attttgtatt acaatatgaa
    19441 gggagttttt tcatgagtta ttcattaaat tggaatctag attctatttt ttccggaggc
    19501 agtcattctg atgctttgaa ccaacggatg aagcaattgg aagaccaaat gaacgagtat
    19561 tatcaccgcg taacaaaatg gtcacctagt tctgacaatg cagagcagtt aaacgctatt
    19621 cttcaattgc aagaaacgat tacgaatggt tttacccaat gcagcagcta tattactgca
    19681 ttgctttctg ccaatgtcaa tgattcagat gcaaaggtct tatcaggcaa gctttacgca
    19741 atgctgcctc gtctgcaatc agccgaaact gtattgtcaa agaaatttgc agaaatatct
    19801 gacaatgatt ggaatcagat gctttctcaa tcttcgtttg aaacaattgc ttttcgttta
    19861 aacgagattc gtcgtgatgg ctcacaatta ttatcagaag ctgaagaaaa cattataaat
    19921 acgctttctt tagatggtct aaatgcttgg agcagtcatt atgatacgat tgtagccagc
    19981 atttcgattc ccttcgaaca agatggacaa gtagtcgaat tatctgctgg acaagccttc
    20041 aataagatga tgggcgatcc agatccaaaa gtcagagaaa cacttttcgc agcatgggaa
    20101 gaagcctgga aagaaaaggc acccctcttc acggatactt tgaatcattt agatggtttt
    20161 agactttctg actatgaact tcatggtgtc acagattttc tacaaaaacc attagagtac
    20221 aatcggttga agaaagaaac attgtctgtc atgtgggata caatccagaa aaacaaacaa
    20281 ccccttgtta attacttgac tagaaaagct aatcttttcg gtaaagaaaa aatggaatgg
    20341 caagatcaag atgcacctat tattttaggc gatttgaaag aaaaaacctt tagttttgac
    20401 gaagcagcag catttattat cgaaaacttt aacaaattca gtccaaaaat ggctaaattt
    20461 gcccaatctg cttttgaaaa gagctggatc gaagcagaag atcgtcctgg gaaacgtcct
    20521 ggtggttatt gtactgagtt accagaaaca aaagaatcaa ggatctttat gacctacagt
    20581 aattctgtta atgaggttgc gacacttgct catgaactag gacatgcttt ccatagcagc
    20641 acgatgtggg atttaccttc tttaaatcgc gaatatgcca tgaatgtcgc agaaacagca
    20701 agtacattcg cagaactgat cgtagccgat gctacattaa aagtcgcaaa aacaaaagaa
    20761 gaaaaaatca atttgctaga tacaaaactg caaaatgctt tagctatgtt catgaatatc
    20821 cattcccgat tcatttttga aaatcgattc tatgaagcac ggcaagaagg attagtctca
    20881 gaagataaga tcacagagat gatggttgag gcgcaaaaag aaggctatca aggagcttta
    20941 gctacttacc atccatattt ctgggctgca aaattgcatt tctttattga tgacgtaccg
    21001 ttttataact tcccatacac atttggctac ctctttagtt tgggcatcta tgcttacgcc
    21061 aaccaaaagg gagcaaattt tgaagaagaa tatatccatt tactacgcga tactgcctca
    21121 atgacgacgg aagatcttgc gaagaaacat ttgaatgtcg atcttaccca accagatttt
    21181 tggcaagcag gtatcgacat ggtgactgaa gatatccaaa cgttcatgga attgacagaa
    21241 gaatttatct gatttctatt ttatcacaat aaaaaaagag ttagtccaga atgggctaac
    21301 tctttttgat taatcattct tacatgctga cagcaaagtc aggggcaaac cattgaactg
    21361 aaccaacttt tacgctttcg cctggttgag gagcatggat atattgtcct ccgcctaaag
    21421 caatcgctac gtggtaagtt ccgccttgtg acccccagaa taacaagtct ccagcttttg
    21481 cttgagaaac tgaaattttt gttccagctg attcttgagg aactgtccaa ccaccgatgt
    21541 cacgaccagt tacttgcatg taaacatagc gtgtgaaccc tgagcagtca aagccacttg
    21601 gatctttacc gccccaaaca tatggagtac caatatattt gtaagcttct gctacgattg
    21661 ctgcaccatt cacacttcca gaaggagctg gagcaggtgt tacaggtttt ggttgttcag
    21721 gtgttggtgt tggcgttgga gccggagtac tacttcctgt gccgtttcct gtatcaacac
    21781 tttgatctgt tgatggtgtt gtaggcgcag gtgttgttga ttcttctgtt gttgaagatt
    21841 caggcactgt tgttgattct tctgttgctg aagattcagg cactgttgtt gattcttctg
    21901 ttgctgaaga ttcaggcgct gttgttgatt cttctgttgc tgaagattca ggcgctgttg
    21961 attcttctgt tgaagattca ggtgttgttg attcttctgt tgctgaagat tgtgtagctg
    22021 atgatgattc ttcagtcatt gaagattgtg tagctgatga ttcttctgtt gctgagcttt
    22081 gtgcagtaga tgaagcttga gtagcttgtg cttcagcctc tgcttgttcg cgtgcttctt
    22141 tttcagcttt ttcttgtgca gcttgttgac gagcttgttc tgctagacgt tgttgttcac
    22201 gaatacgagc ttgctctgct tcagcttctg ctttttgacg gttcaagtca gctttcttgt
    22261 cttcagcagt tgcttgttca gcagctaatg aagttttcag tacgttcaaa tcagcttgtt
    22321 tagataaaag atcgcctttt tgagattcca aagcagcttg gttttcagct aattctttta
    22381 gtttagcatc gttttcagct tttttgtctt ctacagcttt tttatcttgt ttttgttgtt
    22441 ccatcaagtc gttgtttgct tttaccatcg ttgtcattgc ttgaacgcgt ccaatagcat
    22501 ctgctaatga atcagcattc aatacagcat cgatgtagtt tgagcttgtg ttgcttactt
    22561 gtgcttcgcg tgcttgtttt tggattgtat cttcacgttt ttcaatacgt tcttgtaaat
    22621 ctgcaatgtc ttttactaat tgtgcagatt cttgacgcaa tgtatcttgt tttgctaata
    22681 ggtcttgtgc ttgtgtgttg atttcagaaa cttggctttc taaggcatcg atttgtgatt
    22741 gtgcatctgc ttgttgattt ttcaagtctg caatcttttg atcttgctgt tgtatctgag
    22801 aatcaaaatc gtccgccgcg gcagcgatcg gtgatgctac ggcagtcaag gtcattgaac
    22861 ataccattac tgctgatatt aaactctttt tcactcttca ttcctccgac tggcttaatt
    22921 taataaatat ctaaatatat ttaagtcttt cttaacgata taaaaattgt accatagcag
    22981 tgtgtcaacg atataatagt tatgttacaa aaatgtttca aaacaacttt taaaaatgac
    23041 aaaactgttc gtttcagaaa atgatcatga aaaagccgcg ttaagtctag catttcttaa
    23101 gataacaacg attctttttc gctttcgacc taaaaataaa aaaagaaatt attcatcact
    23161 gaataatttc ttaaagggaa aaatgaataa tacaaatata atcatgttca acagcagtgt
    23221 aggtcctaaa aaccttgtaa taaaatacgt gttatttact actgctaatt taaaaatcaa
    23281 ctggaccacc atcgtaaaca attcataacc cgtgacaaag atgatcatac tgaaaaattc
    23341 agtaaagatg ttgacatgga taacgtcttt cattacatac atcaaccata caattaaagg
    23401 gagagctact gcatagatac cgataacgcc aatatagtaa gcgtcataga tagccccgag
    23461 aacaatcgtg gtaatcagta aataacgttt ttcaaacgcc atactgcaac ataataatgc
    23521 caatatcaga aagtgggcat ttgacatata ggtgcctttc gaccactccc ctagcattct
    23581 tgttaaatga ccatctatca acatcaaaaa gaacaaaacg attggcagat agtacttcat
    23641 tgtttctttc ttcaacatgg actaatcctc cgctagccgt tggacaatcg tcacaactga
    23701 cacgtcatac atttctgcat aaggtttcac ataaacttcc cgatccagcc cataactatc
    23761 tggtttcgtt ttaataaccg taccgatcgg caagttagct ggagaattcc ctccaagacc
    23821 ggatgtctgg acaacatccc cttctttgat atccgtatca ccagttaatt gggtcaccac
    23881 taaggcatgg agcttttcat catagttttt aagcaaacca aacgcttcgc cattagccga
    23941 agatacccgt actggaaaat gattggagct ttcattagag gatgacagta attcgatttt
    24001 agacgaagcc gtattgacct cgatcactcg gccaatcaat cctttttgcg acatgactgc
    24061 catatttgct tcgataccgt ctttagaacc cttgtctacg atcagcatgt cctgccaact
    24121 gtcaggcgaa cgagtaatga catttgccgt tactttttcg taactagtca gcgtctgatt
    24181 caactcaagt tcttttttca acgcttcgat ttctctctcg taattcttgt tttgctgtga
    24241 aacgtcatca tagctatcga ttttttcttt tagccgctca ttttcggcat aagttgaaaa
    24301 aagattatgg acagaatcta ctccatttcg tacccaccgt actggggcag agattgtttt
    24361 atcaaccatt gcaacactgt cattaacgat ggattggaag aaattgggct ttccttcatt
    24421 cgctcgctgc gcagcggtca cacttagtat cgtcaccacg atgataacaa taaccaaggt
    24481 aataataata tttttattag gattgaactt cttcacaaag acacctcgaa ttaattagac
    24541 tcttgtgttc aattttatca ctaaatgccg tgaaacaaaa ggtaagttgc tcctcttaag
    24601 ctttttttta gcaaataata gattctgtca tttttagcct gaaagacaaa tttttttatt
    24661 tgtttatgga tcaatctttg ctttgaataa ctgcaatcat accatctgaa aaagaaaatt
    24721 ctgcggtatc tgaaagaaat tcgttacttg cataagatgt cggatattct acttctttat
    24781 tttccaatac atacttgctg ccttttaatg taagattcga gacgggagtc aagcagcaat
    24841 aagctaaata cttcatatct ggtatctgtc ttactatatg ctctccaggc aaataataag
    24901 acaaataatt ttgacaatct ctgataataa gctgatgggc aaagggtttg aagcgaggtt
    24961 ccatacctaa ccagagattg gctaaaagat gatccaatct tccgcccgta gctccaatca
    25021 aagtgacttc cgcttgcggg taacgttcaa atgtttttaa gatacctaac tgtgtatctg
    25081 tatcgtcttt ttctgcaggg gaacgggtat actctttggc ttttgcaaat acttccttct
    25141 gctcttcgtt cgacaatgaa tcaaaatcgc ccactgccag atctactggg tagcctgctt
    25201 gaagcaggta cagcgcacca cggtctatcc cgacataggc atcgtatttg gacagcagag
    25261 actgcggcca gttttgcgga ttacctccag cagctaataa aattttcatt tagtctaatg
    25321 cctcttttaa tcgttcgatt tgtccgactg gattttcggc tccatagata tatgatcctg
    25381 caacgaagac atccgcccct gcatctttac agatttttgc tgtttctgga acgattccgc
    25441 catctacttc gattgcataa gtccaattgt tctctctacg tagatcagcg agttccgtaa
    25501 ttttttctac tgtttcttca ataaagcttt gtccgccgaa cccaggattg acagtcatga
    25561 ctagtacttg atcagccaaa ggcaaaacat gtttgatcat ggagactggt gttcctggat
    25621 tgataactac tccagcttta actcctaagc tttttgtcat ttgaagtgcc cgatgaatat
    25681 gaggagttgc ttcgacgtgg acagtaatga tatctgctcc agcttttgca aatgctggaa
    25741 tgtagttttc tggatcaacg atcatcagat ggacgtctaa cggtaattta gtaacaggac
    25801 ggattgcctg aacaatattt ggccctaatg tgatatttgg gacaaattgg ccatccatta
    25861 catctacgtg gatgtaatct gcgcctcctt tttccactaa ctcaatgtct ctttgtaaat
    25921 tggcaaaatc tgcactcaaa atggatggtg ctatcttcat tcttgtttcc tcctattttc
    25981 gtttaccttc tttttttgca tacattggtt ttcttttttc gatttcttgt aagaattgca
    26041 aataattgtc gtaacgtgtc tgtgcgatac cacctgtttc tactctatgt tttacttcgc
    26101 agccaggttc tttagcatgc atgcactctc taaatttgca atggacagaa gcttctacaa
    26161 attcaggaaa ttgtctcggc agttctcctg cttcaattgt caaaaagtca atcgagctaa
    26221 atcctggtgt atctgctact aacccgccat agataggaat cagttccaca tgacgtgttg
    26281 tatgccgtcc tcttccaagt gcatcagaaa tctctcctgt tgctaaattc agttccggtg
    26341 atatttgatt cagtagcgtc gattttcctg ctccagactg acccataaag accgatagcc
    26401 gttctgggaa gtaacggatc agttctgtcg tatcacccgt atgattgggt acaatcaccg
    26461 gatagcctat tttagtatag gtttgcttga tctcttcgat tttttctggg tcgtctgaca
    26521 agtcggtctt tgtcaaaaaa ataatcggtt cgatcgactc gtattccaag gtaactagaa
    26581 agcggtcaag tagattataa gaaaatgcag gctctacgat acttgtgaca atgattccaa
    26641 gatcaacatt tgtgactggt gggcgaacta attgattttt tctcggcaag atttccagaa
    26701 gatagccgtc tgtttgattt tcactctcaa agatcacctg atctccgaca agcggcgtga
    26761 ttttccgatt ccggaaattt cctcttcctc ttgtttgata ggtctctccg tttgcgtata
    26821 catagtaaaa accgctgatt gcttttctga tttgtccttt gataagtgcc acctccgttt
    26881 ttgtttattt taccatacga agaggaaagt aggtgttatt ccatgcaaac ttctcaaagt
    26941 atatggcttg aaaattgatc aaaagagata gaaacacaaa aaagagaatg caacaaatca
    27001 atgtcgcatt cccttctgat atattttatt cagcacttat tttgaacttt ctgaggtgct
    27061 agctgatgaa cttgtggagc tggaagattc ttcttttgaa gagttgcttg tgctactgga
    27121 gctacttgag ctgctagaac tgtctgaaga gtctttttca gaactagaag acgctggatc
    27181 tggtccttta gagtaaatta cgttcacaac cattcctttg gtaattgtcg ttcctgcccc
    27241 tggtactgta cgaatcactt tatctttatc caccgtgttt gaatattcgg aagtctcatg
    27301 cccgatatat tctgcaccga cactagctaa ataactttgt gcttcgcttt ttgtatagcc
    27361 ggagatatca ttcaatttag gctctgttcc ttggcttacg acaaaattga tgtaagtttc
    27421 ttctgctaca acttcacccg aggctggatc ctgactgatg atcgaacctg atggtacagt
    27481 gtcgctatag tcataagtag cactaatatt attgatattg aatccttgtg taacaagcca
    27541 attacgaaca gtttcgtagt tttctcctac atgactactc aaagtcactg tttctggtcc
    27601 tttgctgact gtgaaagtaa tcgtgtctgt tttaggatcg acttctgtat cttctgatgg
    27661 agattgcgaa atgatcattc cgctttctac ctctgaactg aattcctctt ctttttgaat
    27721 caagtcagca gaaaacccta attctttcaa acttgcttcg gcatcttcat aacttttacc
    27781 actgtaatca tctaatttga tttttttcgt gccgctacta atatacagag tgacttcgcg
    27841 tttttgcttg actgtcgttc ccgctgccgg gtctgtcttc actacattac cttcttcgat
    27901 tttgtcatct gcaatttctt ctgtttttgt tgctacttct aatttcgctt ttgcgagtgt
    27961 ttctctagca gaagcttcag aaagatcaga aacatcagga acaacaactt ctcctcgccc
    28021 gccagaagca aagaatacag ctgttccgat tcctaaaaca gcaagaatag ctaataggat
    28081 cagccaccat tttttctgtc ctttcttttt aggatcaggc agaacttctt cctcctctgg
    28141 caaggtttcg ttttctggct tgtcttttgg cagaggcata gatttgaatg aatcaggcat
    28201 tggtgcatct tccgtaaggg gtgtgataac ttttgtttca ttatccatca catgaggctg
    28261 ccatttttct tcgtttgcac gagctggtga taatactgta gaaagatcat cagacatttc
    28321 ctcggctgac ttataacggt ctgcaggttc tttagccgtt gcccgtaaaa tcacgttttc
    28381 cagtgcttgt ggcacatttg gatcaagtgc ttttatagat ggaagatcat cttgaaaatg
    28441 ttttaaagca attgttacag cagattcacc atcaaacggt acgctacccg tcaacatctc
    28501 ataaaggatg atccctaaag cataaatatc tgactgcttc gttgccatac ttcctctggc
    28561 ctgctcaggg gacagataat gaacagatcc cagcatcgta ttcgtctgcg tgatcgatgt
    28621 ttcagataaa gcgatagcaa tcccgaaatc cgtgattttt acaacacctt cattatcgat
    28681 cagtacgttt tggggtttca aatctcggtg gatgatttga tggttatgag ctaaagaaat
    28741 agcagaaagg atctgctgca taatatttac tgctgtttca taaggaacag gataatgtgt
    28801 ttggatatat cgtttcaagt ccattccttt gacgtattcc atcaccagat actgcatgtt
    28861 gtcttcttca ccaacatcgt aaacactaac aatgtttgga tgaacgagtt ctgttgctgc
    28921 taaagcttct ctctgaaatc gtcgaatcgc agtctggtca ttttgaaagt caaatcgtaa
    28981 gactttaact gctacatcac gatccaagat taaatcgtgc gccaaaaata catttgccat
    29041 accaccgcta ccgatatttc cagtgatttg ataacggcca tttaattttt tgcccaactc
    29101 gatcatacac tgtcctcctt atattcgata agaagaacgg tgatattatc cgctccgcct
    29161 gcttcattgg cacgatcaat cagctcagtt actttatgag acaatgggcc ttcttgattg
    29221 atgatcgttc ctatttcttc ttcagacagc atgttcgtca agccatctga acataacagc
    29281 agtcgatctt ttagttgcca aagatgagta gaaacatcta cttcgactgt tccaggcatg
    29341 ccgacagaac gtgttaaaat atttttcctt ggatggttca ctgccatttc ttcgctgatt
    29401 tctcctgatt tgactagttc attgactaaa gaatgatcct ccgtcaattg catgatttta
    29461 tcttcacgaa tcaaataagc tctgctatcc ccaacattgg caatcgtgaa ccagtcatct
    29521 gacagagcgg ccgctacgat tgttgttccc ataccgttat attccggctg ttcttgtcca
    29581 cgctgataaa tcagcatatt ttcttcttga atcgattgaa tgaaccattg ggcgattttt
    29641 tcatcgtcaa cagcttcttg tttttcccaa gcttcgccta gattcgttac cgccatctga
    29701 ctggcaatgt ctccggcacg atgaccaccc atcccgtctg ctaatacagc aagcttgaga
    29761 cctgaacggc tggtaaatac actggcatag tcttgatttg tgttacgtcg tcttcctaca
    29821 tctgattgat attcaatctg cattttttca cctcattact ttttgcgcaa acaacaaatg
    29881 aaaaatccat ctgtgtaaaa ctgatgcgga tacaaagtca acattttctc ttcgattgat
    29941 gattgtagca taggattggt caaaacatca atcctctcaa aatcagggtg tctttccaag
    30001 aaagcagaaa caacgtcttg gttttcttct tttaagatcg tacaagtgct ataagtcaga
    30061 ataccggaag actttaaagt tggtgcgcag ctttctaaaa tttccaattg gatttttggt
    30121 aaattcgcta attcatccgg ctgtttttta taacgaatat ctggttttcg ccgaagcagc
    30181 ccaagacctg aacaaggcgc gtctactaaa atccgatcaa actgctctgc ttcgaactgt
    30241 ttactgactt ctctagcatc catcttttga gcgtagacag cagaagagac acctagacgt
    30301 gctgcattat cttcaatgag tttgactttg tgttcgtgta catctaaagc gaccacttct
    30361 ccaccgcatg acggatctaa aaaagaagca atatgcgtcg tcttacctcc gggtgctgca
    30421 caggcatcta agacatgatg ttcaggctcg atttgcatag acggcgctac aagcatcgaa
    30481 ctttcatctt ggatcgtcat gacgccatcg tggaacaatg agctagaagc taaatgccct
    30541 tttttcgcta ctataccgta tggactgact tggctttttt cagctgtgat ctcttcttct
    30601 tgcaaaacag tgatggcctg atctctggaa agtcggcgtg tatctactcg ggcactagca
    30661 tggctaggct gatatagcga taaaccgagc ttttcagttt cttcgtatcc gatttgatcc
    30721 accagtcgtt tcgtcatcca tagaggcagg ctgattttga cagaaagtct ttcgatagga
    30781 tcagcaatgc cttgcagatc tggtgctcct tgacgctgat aattcctcaa gacaccattt
    30841 acaaatttcc ctgtcccagg atttcctttt acttttgcga tttcgaccgc ctcgtttaaa
    30901 atagcatgtg cagggacttt atctaaaaat tctaattggt atacagaaag ataaagaagc
    30961 gtcttgaccc agtcatccac tttttttgct ttagcgatca atggtgcaac gtaaaattcc
    31021 aatagtcgct gatggctaat cgtaccatag atcaattctg taaataaacc cacatctttt
    31081 tgatttagct cgctttgttt gatcatctca ttcaacaaaa gattcgagta ggcgccaccc
    31141 ttgttcactc gctctaatgt cagtaatgcc atatatcgta ctgatttttt cattttttta
    31201 gggatttttt tcattatttc acctgctgac caatctgaac ttgctgaccg cttccgttaa
    31261 ggaaatcatg tacggcctgt tttcctttac cagctggctg taattcattg atggctaaga
    31321 cggtctgttt accgcaagca atccatagat tttttttgtc tttccggatg atcgtaccag
    31381 gtgctttgtc tgtagtttct gccaatactt caaccgataa taatttccag cgtatgccct
    31441 cataggtcgt gaatgcaatt ggccaaggac gcattccgcg tacttggttg tcaatttctt
    31501 ctgcagtttt atgccaatcg attgcttctt gttcccgtgt gatgtttggc gaaaaagttg
    31561 cttctgactc gtcttgaggt actggttttt gtccatccaa aatattgggc aatgtttcta
    31621 gcaatagctt tcttcctaaa aggctaagct tttcaaacat cgtccctaca tcatcttgtt
    31681 tagtgattgg tatgctttct tgcgcataga ttccgcctgc atccattttt ttgatcattt
    31741 ccatgatcgt tacaccagtt tctttctccc cattcatgat ggcataatga acaggcgcac
    31801 ctccccgata tttaggaagt aaagaagcat ggacattgat tgcccctaat tttggtactt
    31861 gcaataactt ttcaggcaag aattggccaa atgccgcagt gacgatcaca tcaggcacca
    31921 attcaatgat ttcttccatt tctggcgaac cggagatttt ctctggctgc agcacacgga
    31981 taccgtgctt cagagccgct tcttttaccg gtgtcggcgt aattactcgt ttccgcccaa
    32041 ctggacggtc gggctgtgtt accactgcct ggatctcgta acctgattct atcagccctt
    32101 caagaatcgg cacagaaaaa gcaggtgtgc ccataaatac tagcttagtc atcaagatgt
    32161 tcctccatat attcttcaag ttcttcttcc gggatctgct gtatcatttt ctcaatgaac
    32221 aagataccgt ctaagtgatc gatttcatgc tggaaggcac gggctaaata gccaaaagcc
    32281 gtcacttcta tctcttctcc gtctcgatca taataacgca cggtcacttc atctgctcgc
    32341 ttgaccgttc catagacatg cggaatactg agacaacctt ctacgtcaag gctttcacct
    32401 tttgcttcga tgatttctgg gttaatcagt tcaaatttct cgccttcatc tacttcgatc
    32461 acagcaattc tcttgttttg tcctacttga ggagcagcga tccctattcc gtcattcgca
    32521 atcattgtct catataaatt gtctaataaa gcgattgtct cgtccgtgat tacatcgatt
    32581 ggctgagcag ttctttttaa tttatcatta gggtggatca atataggata gcgcataatt
    32641 tggccctttc ttaaataaag tttaatggtt cgttgtcaat tgccacaaaa agaccttgtc
    32701 gctgttcttt ctggcttcca ttcaaaattt catccaaaac atgaggaaga ttcggttcat
    32761 gtttatattt gatgattagt tgataataat atcggttttt cactctcaaa atcatgctgg
    32821 gcgttggccc taatagcaag ctttgagggc ttaacacttc ttttagctga ttggcaatct
    32881 gaaagatttt ctttgccgct acttgttctt caggatggct ggcggttatt ttcacagtaa
    32941 agtaataagg aggatagcct ccacgatgcc gtacatgcat ttcctgctga taaaactgct
    33001 cataattttg ttttttagct aattctatgg cgtaatgttg aggattgaat gtttggatca
    33061 cgacttcgcc tgctttttcc gctcgccctg ctcgtcctga aacttgggta agcaattgga
    33121 atgtatgctc actagaacga aaatccggta aattcaggga ggtatcagca ttcaacaccc
    33181 caactaatgt cacttctgga aagtccaaac ctttagcaat catttgtgtc cctaataata
    33241 tatctgcttc ttttgcaccg aatttttgta aaatctgttc gtgtgcccct tttcttcgag
    33301 tggtatctac atccatacgc aaaatcctag cttgcggata aagttctcgg agttcctctt
    33361 ctactttttg agtacctgtt ccatagtagc ggattttatt gccgccacaa ttaggacagc
    33421 gattgggaat aggttcttca tgtccgcaat aatggcagcg cattgaacgt gtatccatat
    33481 gcagtgtaag agagatatcg caattaggac atggaagaac aaatccacag tccctacaca
    33541 tcacaaaaga cgaatatcct cgacgattga gcagtaggac agtttgttct tttttgtcta
    33601 atcgattttg tattttttcc tgcaaattag cagaaaaagt agaggtccga tgattctgaa
    33661 actcttcacg catatctacg atctcaatag ctggaagctg tgcagctgct ttggctcggt
    33721 ggtttaactg caataactga taaacgcctt tttgagctcg tgctcttgat tctaaagagg
    33781 gcgtcgcgct tcctagaact attgggcaat gatgatattt actgcgccaa attgctagat
    33841 ctctcgcatg ataacgcggt gtctcatctt gtttgtaact tgattcatgt tcttcatcga
    33901 taatgatcag cccgatattt ttcagcgggg caaaaatagc agatcgtgcg cctactacta
    33961 cttgcgcttc ttcccgctca atcttgcgcc attcatcata tttttcacct tgggaaagtc
    34021 cgctatgtaa gaccgcaact gattctccga agcgtccttt gaatcgctcg accatttgcg
    34081 gagtcaatgc gatttcaggc actaacataa tagccgtttt attttctgac aaaacatcag
    34141 cgattgcctg aagatatact tctgttttcc cgctgccagt gattccctcc agcaaaaaga
    34201 cctgatcttt ttgctgctga cctgctgtga tgatttgttc gacagcattt ttttgttctg
    34261 cattcagttc caatgccgtc gtttggtcaa atactcggtc tttataaggg tcgcgataac
    34321 gttctgattc tataaactcc agccagccct tttcttttcc ttgattcaag acagcagtac
    34381 tgattccttt atttttgaaa taagcaattg gttcttcttg gctcagttca gataaacaca
    34441 aaagaagttc tttttgtttc ttggcatttt gccgtaattt tgcccattct tcttcgattt
    34501 gcttttcagt taacaaagaa cggaccaaac gaatcgtttt tactttattt cgtgtatgga
    34561 cttcatattt gatatctact aattgctctt ggcgccagcg aatcaattga gaaaggctgc
    34621 cttcttcttc tgcttccttc caggaaatca cttctcgctg atcaaacaat acctgaactt
    34681 ctggtgtgtc tgccaaagga tagatcaatt tatcatattc tgctttcatc acactcggaa
    34741 gcatcgtttg tagacaagtg attttgaatg cgtaagtaat ttttttcata taatcagcta
    34801 atgaaagtaa ttcttcattg accaccggag caaggtctag caaacgaata actgccttca
    34861 aagatggatt agctgattct tctgattttt ggatagccat aacaaatcct tggacatgac
    34921 gattgccatt accaaaaggg acttctactc gcatcccgac ttgcaaagct gtttccattt
    34981 cagagggaac caaataagtg aatggctgat cggtctgcat agtaggtacg tccacaatga
    35041 cttcagctgt taatgtcatg gttcgtttcc tccttttttt gtcttttctt atcaagcgac
    35101 aaaaagttcc ttgcctattt tactagagat cgatggattt gtcttatctt ctgccaaatc
    35161 ctaacaaaaa attaacagca gataagaaaa aaaagaactg tgtcaaaaag ttcagacaca
    35221 gccttttcta ccagacaata agtggcgaat gtttgaaaag gaaacagctg ggtttgcttt
    35281 tctttttaga tgttcgctct atttttcttt attacatttt ttgctcttca cggatacgtg
    35341 attccaattc gtgttgttca cgctcttttt gtgcttgacg ttcctcttct tccatcttca
    35401 aacgttcacg ttttaattca ggatgtggat cattgactac atttcctgca tcgatttctt
    35461 ctaaagcttg accgacgctt tttactgaat caaaagaatc tagagtaggc tgtgcacttg
    35521 catccaattc atgcgcgcgt ttacttgcta aaatcactag agaatatttt gaatttacac
    35581 gatctaatag tgagtcaatt gaaggtttta acatcataag actacatctc ctttaacatt
    35641 ttaatatatt taccgattac gcgatctact cgaaaatgtt cactggcaat aatgtttttg
    35701 attcgttcaa ctgctagcgg cacttcatca tttacaacag catagtcgta aagagccatc
    35761 atttcgattt cttcttttgc aactttcatt cgttcttcga ttacttcatc tgcatctgtt
    35821 cctcggccta cgatccgtga ttttaattcc gctaaatctg gcggagtcaa aaagatgaat
    35881 acaccatcgg gcactttttc tttgacttgt tttgctcctt ggacttcaat ctccaagaaa
    35941 acatcttttc cttcatccaa tgtcttgttg atatatgaca aaggagttcc ataataattc
    36001 ccgacatatt ctgcgtattc cagcatctct ccagcttcga tcattgattc aaactcttct
    36061 ttgcttcgga agaaataatc aacgccttcg acctcccctt cacgcatttt acgggtagtc
    36121 attgagatcg aatactgaaa atcattatcc tcactctcaa aaattgcttt tcgtactgtg
    36181 ccttttccta caccggatgg accagacaac acgattaata atccacgctc tgacatgacg
    36241 acgtcctttc aactagtctt tttgtactta tcgtttattt tgcacttttt ttctgcaact
    36301 ttcaaggtta tctttaatta tagctagaaa ttggtaaaaa agctaccctg taccaagagg
    36361 tcgtaaaaaa gctgtcctgc atcaagtaat aagaacagcc aaacataaac agcttctcat
    36421 gtttttcgtt tggttggggt tattatcgca gatgcaagct tttgaacgcc gtgtataaga
    36481 ggtcgtgaag aagccgatta gtttcgagta tgaagaaaaa ttttgtgaaa atagtttctc
    36541 acatttttgc ataaatttgg cttaata
//
LOCUS       DADVXM010000019        35082 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.020, whole genome shotgun sequence.
ACCESSION   DADVXM010000019 DADVXM010000000
VERSION     DADVXM010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.020"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(47..895)
                     /locus_tag="KB927_001046"
     CDS             complement(47..895)
                     /locus_tag="KB927_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6839980.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1117..3060)
                     /gene="thrS"
                     /locus_tag="KB927_001047"
     CDS             complement(1117..3060)
                     /gene="thrS"
                     /locus_tag="KB927_001047"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBB6839981.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSRENK"
     gene            complement(3397..3576)
                     /locus_tag="KB927_001048"
     CDS             complement(3397..3576)
                     /locus_tag="KB927_001048"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBB6839982.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3623..5446)
                     /gene="cadA"
                     /locus_tag="KB927_001049"
     CDS             complement(3623..5446)
                     /gene="cadA"
                     /locus_tag="KB927_001049"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBB6839983.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHAHSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5724..8003
                     /locus_tag="KB927_001050"
     CDS             5724..8003
                     /locus_tag="KB927_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6839984.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETEIDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8096..8743)
                     /locus_tag="KB927_001051"
     CDS             complement(8096..8743)
                     /locus_tag="KB927_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6839985.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNNVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8922..9641)
                     /locus_tag="KB927_001052"
     CDS             complement(8922..9641)
                     /locus_tag="KB927_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6839986.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9772..10923)
                     /locus_tag="KB927_001053"
     CDS             complement(9772..10923)
                     /locus_tag="KB927_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBB6839987.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKTTGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTYSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDVGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11140..11880)
                     /locus_tag="KB927_001054"
     CDS             complement(11140..11880)
                     /locus_tag="KB927_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6839988.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEIFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11884..12240)
                     /gene="rsfS"
                     /locus_tag="KB927_001055"
     CDS             complement(11884..12240)
                     /gene="rsfS"
                     /locus_tag="KB927_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBB6839989.1"
                     /translation="MIDSKEQLKIAVEAADSKRAEDIIALDIRNVSLLADYFMICSAN
                     SERQINAITEEIIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERSFYNLE
                     KLWSDAPLVDLSEWLD"
     gene            complement(12264..12857)
                     /gene="yqeK"
                     /locus_tag="KB927_001056"
     CDS             complement(12264..12857)
                     /gene="yqeK"
                     /locus_tag="KB927_001056"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBB6839990.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDVEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12841..13491)
                     /locus_tag="KB927_001057"
     CDS             complement(12841..13491)
                     /locus_tag="KB927_001057"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBB6839991.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13501..13812)
                     /gene="yhbY"
                     /locus_tag="KB927_001058"
     CDS             complement(13501..13812)
                     /gene="yhbY"
                     /locus_tag="KB927_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBB6839992.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13828..14937)
                     /gene="yqeH"
                     /locus_tag="KB927_001059"
     CDS             complement(13828..14937)
                     /gene="yqeH"
                     /locus_tag="KB927_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBB6839993.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14934..15461)
                     /locus_tag="KB927_001060"
     CDS             complement(14934..15461)
                     /locus_tag="KB927_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBB6839994.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15688..16473)
                     /locus_tag="KB927_001061"
     CDS             complement(15688..16473)
                     /locus_tag="KB927_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBB6839995.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRFDQHELLEKRYKRFRQY"
     gene            complement(16466..17335)
                     /locus_tag="KB927_001062"
     CDS             complement(16466..17335)
                     /locus_tag="KB927_001062"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBB6839996.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17336..18715)
                     /locus_tag="KB927_001063"
     CDS             complement(17336..18715)
                     /locus_tag="KB927_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBB6839997.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFFSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDHF
                     GNVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18723..19142)
                     /gene="fabZ"
                     /locus_tag="KB927_001064"
     CDS             complement(18723..19142)
                     /gene="fabZ"
                     /locus_tag="KB927_001064"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBB6839998.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19167..19643)
                     /gene="accB"
                     /locus_tag="KB927_001065"
     CDS             complement(19167..19643)
                     /gene="accB"
                     /locus_tag="KB927_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBB6839999.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPETMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19646..20881)
                     /gene="fabF"
                     /locus_tag="KB927_001066"
     CDS             complement(19646..20881)
                     /gene="fabF"
                     /locus_tag="KB927_001066"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBB6840000.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20900..21637)
                     /gene="fabG"
                     /locus_tag="KB927_001067"
     CDS             complement(20900..21637)
                     /gene="fabG"
                     /locus_tag="KB927_001067"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBB6840001.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21649..22566)
                     /gene="fabD"
                     /locus_tag="KB927_001068"
     CDS             complement(21649..22566)
                     /gene="fabD"
                     /locus_tag="KB927_001068"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBB6840002.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22673..22897)
                     /locus_tag="KB927_001069"
     CDS             complement(22673..22897)
                     /locus_tag="KB927_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBB6840003.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22950..23912)
                     /locus_tag="KB927_001070"
     CDS             complement(22950..23912)
                     /locus_tag="KB927_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBB6840004.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23922..24362)
                     /locus_tag="KB927_001071"
     CDS             complement(23922..24362)
                     /locus_tag="KB927_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6840005.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24668..25633
                     /locus_tag="KB927_001072"
     CDS             24668..25633
                     /locus_tag="KB927_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6840006.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRAQLPDLQ
                     EMTFEQKKKELQGLFQGQNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKHFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMIASADVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQSEIELLNKKEAEKQLN"
     gene            complement(25690..25920)
                     /locus_tag="KB927_001073"
     CDS             complement(25690..25920)
                     /locus_tag="KB927_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBB6840007.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(26006..26893)
                     /locus_tag="KB927_001074"
     CDS             complement(26006..26893)
                     /locus_tag="KB927_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBB6840008.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26982..28205)
                     /locus_tag="KB927_001075"
     CDS             complement(26982..28205)
                     /locus_tag="KB927_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6840009.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28222..29268)
                     /locus_tag="KB927_001076"
     CDS             complement(28222..29268)
                     /locus_tag="KB927_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6840010.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYSIRVPIQAISNGIDLEKYRPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29432..31159)
                     /gene="ptsP"
                     /locus_tag="KB927_001077"
     CDS             complement(29432..31159)
                     /gene="ptsP"
                     /locus_tag="KB927_001077"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBB6840011.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(31159..31425)
                     /locus_tag="KB927_001078"
     CDS             complement(31159..31425)
                     /locus_tag="KB927_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBB6840012.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31904..34138
                     /locus_tag="KB927_001079"
     CDS             31904..34138
                     /locus_tag="KB927_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6840013.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGISVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34286..34606
                     /locus_tag="KB927_001080"
     CDS             34286..34606
                     /locus_tag="KB927_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBB6840014.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34811..35035)
                     /locus_tag="KB927_001081"
     CDS             complement(34811..35035)
                     /locus_tag="KB927_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBB6840015.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
BASE COUNT         9881 a         7573 c         6101 g        11527 t
ORIGIN      
        1 tacgttttgt tattctaaaa aacttatata aaaaatagta aggtttttat ttcgaatcca
       61 taaaatattc ttggattgct tctcgtgttt ttttcacttt ttcgctaagc ttttcgtttt
      121 tagccatata gaaataaaaa atgatatcga tcgtagcaaa ttgggccaaa agtgaattag
      181 ttgccgcact tcgattcgtg atttcttttg gtctagatgt ttgtacgagt acatcggcta
      241 tcttgctaag cgggttattt ccaaattgcg tcaacgcaat gatttcgata ttcatgcttt
      301 tcgccagctc ggctaatgcg actacatctg cacttctacc tgagtttgaa acaagccaaa
      361 gcactttctt tttctcattg ctgacaagtt gcgggagcaa gacgtggata tctttttcaa
      421 aaatgattgg cttaccgaca cgagaccatt tttgcagaat atcttctact actaaagaag
      481 aggcgccaac cccatataaa aaaacagtct ctgccgattc caaacactct acgacttttt
      541 ggatcgtttc ttcttctaga atatctactg tttcttttat cgctacttgt gcattgttac
      601 caagtttgtt tttgatagag taaaaggact catttgcttc tatatcacta aaaccttcat
      661 cgattccagt ctgtagttct gttgaaatcg tgattttgaa gtccgtcaga ctttgaaaac
      721 cgattttttt ggaaaaacgt acaactgtcg gcgcactcaa cccggaagct tctgctaatt
      781 cattagctgt cattgtaggg accttctcaa tattaccgat aatgtagttg gccaactttt
      841 tttctgctga agaataatct tccatcatac tttcaatacg actaattacg ctcataagtt
      901 cctccaccct tttaatgata gtctatgtaa gtataccata tcagaccctt gttaacggtc
      961 gtgtactgga taaaaaaaca aaaaaacaat ccgcacaata ggatatctta ctccatcaat
     1021 cccacaaatt ctattgtcca tctgtgggat tgtggaatat ctgttctcta ttgtttggat
     1081 tgttttttat ttagtgcttt tttataggca gcttatctat ttgttttctc tgctgtaatt
     1141 tttgacttct gcttccatag catcaataaa gatattcaaa tcttctacag ctgtttcttt
     1201 acttccataa cgacgtacgt tcactgttgc atcttccaat tccttgtctc caacaaccaa
     1261 ttggtaaggg atcttttgtg tttgagaggc acgtatctta tagcccattt tttcattacg
     1321 atcatcaact tctacacgca accccttcat ttgcaaacgt tctttgattt cataagcata
     1381 atcgccatgt gcatcaacag aaacagggat gattgttgct tgtattgggg ccaaccatgt
     1441 tggaaaagcg cctttgtata cttctgttaa ataagcaaca aaacgttcca ttgtagaaac
     1501 gattccgcgg tggataacta ctggacgatg cgtattttcc ccgtcttctc caacatatgt
     1561 caaatcaaag cgctctggca ataagaagtc taattgtata gttgataatg tttcttctgt
     1621 accaagagct gttttgactt gaacatctag ttttggtccg taaaaggctg cctcgccttc
     1681 tgcttcaaag taatctagtt ctaattcatc catagcggct ttcagcattg cttgggcttt
     1741 ttcccacatt gcgtcatcat caaaatattt atctgtattg tttggatcgc gatagctcaa
     1801 gcggaaacga taatctgtaa tattgaagtc agcatatact gccaccatca attcaagcgt
     1861 acgtttaaat tcatctttga tttgatcagg acgaacaaat gtatgaccat cattcaacgt
     1921 catttctcgt acacgttgta aacctgacaa agcacctgat ttttcatagc gatgcatcat
     1981 tcctaattca gcgatacgaa ttggtaattc acgataagaa tggatcgtgt ttttgtagac
     2041 catcatgtga tgagggcagt tcattggacg aagaacaagc atttcgccat ctcccatatc
     2101 cattggcggg aacatgtctt cttgataatg atcccagtgt ccagatgttt tgtacaactc
     2161 aacatctccc attattggtg tatatacatg ttggtaacct agactaactt ctttgtctac
     2221 gatataacgt tcgatcgtgc gtcggattgt tgcccctttt ggaagccaga atggcaaacc
     2281 agaacctact tctggggaaa ccatgaacaa gtcaagttct tttcctagtt tacgatggtc
     2341 tctttctttt gcttcttcac ggagacggat atattctttc aaagctttct tgtcaaaaaa
     2401 ggctgtcccg tatacacgtt gcatcatttg attgtttgag tttccacgcc aataagcacc
     2461 tgccactgat aataatttaa atacttgtat acggccagtg gatggaacat gtggtccacg
     2521 acacaaatcg atgaattcgc cttgttgata agcagtaatc acttcttctt ctggcaattc
     2581 actaatcagt tctactttgt acggatcact tgcaaaaatt tctaatgctt cctgttttga
     2641 aagaacacgg cgttcgattg gcagattttc tttgacgatt ttcatcattt ctgcttcgat
     2701 tgccggcaaa tcttctgcag ttacttggtt ttgtccatta tctgtatcgt agtaaaaccc
     2761 tgaatcgata gctggtccaa cgccaaagtg gatatttgga tagaggcgac gcatggcttg
     2821 ggccatcaaa tgagctgctg aatgacggac taagccaagt gcatcttcat ggtctggtgt
     2881 gatgatctca atacttgcat cttcctcgat tggacgagtc aaatcaacga gttttccgtt
     2941 cactttacca gctaaagctt tttttgctaa gctttttgaa atgctttcag caattgccaa
     3001 tgttgttgtt ccagactcaa attctttgac tgcaccatct ggaaaagtaa tttttatcat
     3061 aatagtttcc tccttgaaat gttttgattg atcagatcat caagctgaaa aacaaaaaaa
     3121 tcctagcatc tcttgaaaag agatactagg acgaaaagtt cgtggttcca cctaatgttc
     3181 aaacgcaaat gcgttcctca agcgttgtaa cggtccgacc gcccttgctt caacaagggt
     3241 ttcgaaagtg gtcatccttt ggttttctcc tggaaaagtt tcagcctagc ttttcctctc
     3301 ttatcgaaga ctctcaaatt cagttggctt tctcatcaat caattatgtg tttatttaac
     3361 cactaataaa tagaaaaatc aagtgggaaa ctaaacttat tttttccatt ccccatttac
     3421 accgtatgtt ccttttttca tctcattgat gatgacatgg atgtgttctt ttggtgcctg
     3481 cgtgttttta tgaacagctt ccgtgatatc tttcatcata ttttctaatt gttccggact
     3541 gcgaccttct actaattcga catgtacgaa tggcataatg ctctctcctc tttctgatcg
     3601 ttcttttttc aactcgattc tatcatacta tgtttgtctt gggtactgaa tcaggaaaaa
     3661 tggctggatc tttttttgct ctcaaggcac tcaaaataga gaccgtatcc acgacttctt
     3721 gcaaaacagc tccgaataat gcggggatta gtcccgtact tgcaattaac atcaaaaaaa
     3781 tacaaataaa gatgccaatc agtacagact gtttagctat tctcatcgta tctcttgaaa
     3841 tcactactgc ttttgctaca cgcaagagat catctttcaa gatgaccgca tctgcacttt
     3901 cactagcagc tgtagaacca tgagccccca ttgcaatacc gatatctgca gcagcaagtg
     3961 ctggagcgtc attcacgccg tctcctacca tcgcaacagg tctttgatct ttagggatac
     4021 tttctaaaat ggtcagttta tcttgaggca agctatgggc atgtacagaa tctaattgga
     4081 ctttttctgc aatcgtttga gcaatggcag atccatcccc ggtgatcatc atcaaatttt
     4141 tcacatcaag ttttcttagc tccttgattg tctttgctgc ttctgggcga atctgatccg
     4201 aaaataggat cgttcctgca aaagatcgat caattgttac atagattgct gtattggacg
     4261 tttctatttc ttcagctgaa acaaaagagg cacgtccaat ctttacttca tgattattga
     4321 ctactgcttg gattccttga ccggtcactt ctttcagttg actaacagga tacagttggc
     4381 tgtttttcac gttgttcact aacgaacgag ctaagatatg gctagattcc tgttctgcac
     4441 tagctgcata cagaagtagc tcttcttttt ttattccatt gactggctga atcgcctcta
     4501 cttccaatat ccctttggta agcgttcctg ttttatcaaa agcaatcgtt tttgtacgtg
     4561 cgagcttttc aatcgttgtt ccagttttta caacgatccc gtttttactt gaacggctca
     4621 ttcctgcaac taaagcaatg ggcgcagcta gaatcagtgg acaaggtgat gccactacca
     4681 gtacctcagc aaatcgtaaa gggtcttttg agaaccacca agaaatacca ccgatcaaat
     4741 aagcaatcaa cgtgaaaggg actgcataac gatcagctaa acggacaaat cgggcaggct
     4801 tttcttttga ttcttcgact agtttaataa tcatttgata ctggctgtct gcggcacgtt
     4861 tttcagcgat catttggatc gatccgtctc catttaaaga ccctgacata atctgatctc
     4921 caggtttctt ggtttccggg cgggactcac ctgtcaaaga agattcatcg accgaagatt
     4981 ctcctttggt cactcgacca tctgcgggta caagttcgcc aggcttgact agtaactgat
     5041 catcaatatt tatttcatcg attactatat cctgcaattt tccttctttg aatcgatggg
     5101 caattcttgg ggtgttatct aacaaagact gcagttcttt acccgctcgt ttattcgcgt
     5161 aatcctctag actatctccg cccgtaagca tgatcaatat catcaaacta gcccagtatt
     5221 ctttgacggc taatgttgca aggattgcgg taatcgctaa tacatctacg ccatatcttc
     5281 ctgaacgtaa cgtcttgatc atttccaaaa acatcaagaa ggcgagaatc cctccagtaa
     5341 atgcgacaat cgcaaatgca agggccggct ggtgaaaaac aaattcactt aataaagcta
     5401 tcccaccaat aagcaaagta agtaaaaatt ttttgaaatg tgtcattgtt ttttctcctc
     5461 ttttatgtaa cttagagagg ttagtaataa atttccagct gcctctttca tcttaagcat
     5521 agtccttgac tagcactttt taaaacaata ggccttaatt gaaaacaact atcactatca
     5581 gcgtttccaa aattcatcag ttctacaaac aaaaatattc agcaaggatt actttttcga
     5641 ttcatcagtt aaaaagtacc ttttttcgaa aaactatgct atacttttaa ttcgttattt
     5701 acggcggaag gagcaaacat gcgatgaatg agaaacaact agaacaaacg cacgtggatg
     5761 aaacgatcga actaatccag atcgaacaaa atatgctgga tacaaaacaa caagaattga
     5821 ctcaggaaat gaatcattcg acaaaagaca cagctaatca caagattcga gctggttcca
     5881 atgaagcttt ttatgaatct gctgttgaat atcgccaaca tgagcaggaa ttgcttttga
     5941 aataccatac tcttgaagca cagcaaaaac gcctgcaaac gttgtctgtc atgaaagata
     6001 gtccttattt tgcccgtatc gactttaaag aagaccgtga aacagaaaca ttatatctag
     6061 gtatcgcttc tttaagagat ctggcagaag aaacaatcgt tattgactgg cgtgcaccaa
     6121 ttgccaatct ttattatgaa ggtgagattg gtcccgcatt ttatgaaact gaaatagata
     6181 gaatagatgt cgatctgcag ttgaaacgac aatttaaaat ccaagaaggt cgtattttat
     6241 ctatggtaga tacgtcggaa gtaatcaatg atgacttttt gctagagata ttggatgaat
     6301 catcaagcaa ccatatgaaa aacatcgtct ctacgataca aaaagcacaa aatgcaatca
     6361 ttcgggacac aacaagtaaa gtaatgctga ttgaaggaat cgccggaagt ggaaagacat
     6421 ccgctttgct tcaacgtatt gcttttctgt tgtatcataa tcgcaagtgg ctcgaggctg
     6481 aaaacgttct tctattttca cccaaccatt tgttttctga ttacatctcg actgtattgc
     6541 cttcattagg tgaaagcggc gtgcctacac agacattcaa aaattatttg gtgcagctgc
     6601 tgccagagtt ttctttacta gatgaacagc aacaagaaag tggttttttg ctaggggaaa
     6661 aagatccgat acaagtgatg aaaagcggat tgaccttagt cgatcagatt gatcgctata
     6721 tccaaggcat cacaaactac ggtcccttgt tccgtgatat gaaaataaat ggccgtacga
     6781 tcctatcaaa ggaatcgatt cgccaatggt ataaagaaac aaatgaacaa ttgcctttac
     6841 atcatagact ctctctatta caaacgaagc tcctgaaaaa attaggcggt ctgcaaaaag
     6901 acgaaacacg tcagcaatgg gtcaaagatc tggcggaaga acagctccaa gaactatacg
     6961 caacagatcc aaatcttgaa tatacagaac aaaaggagcg ttcattacgt aaaaaactgg
     7021 ccaaccaaat cgtacgtaaa agattccgtc gaatccatcg agggatcatg aattatcaat
     7081 ttgtcaatat aacgaaacaa tatctccact ttctacaaac tgtgccactt tctcttctaa
     7141 cacgacataa aatcagcgag accagatggc aggaacattt gacaactgtt cgtacacact
     7201 tgcgtcaaag agaattgcgt caagaggatg ctgtactatt ctttttactg atgcgccgaa
     7261 catatccagt gacggttaca cacaaagctc gctatatctt tattgatgaa atgcaggatt
     7321 tcgcaccatc acaagtggca ttgctgcaag ccttgttccc aaaagcaaat ttgactttct
     7381 gtggagatct aaatcaaaat gtctttggaa atgaaacgat cgttggatca ttggaagacc
     7441 ttttcgtgga ccgtgaagtc actcgtttcc aattaacgac aagctatcgc tccacaaaag
     7501 aaatcactga ttttgctaat cattttattg tgaaagaaca tcaagtagaa acaacagcaa
     7561 gaaaaggaga ccttcctttg ctcatccaag gaacaacaga tgatatcaaa ttgaattggt
     7621 tagcagatac cattcgaacg actcagggaa aagcccggta ttggcgtaca gcaatcatag
     7681 ctaaaacaca agaagaatgc gaagctcttt atgctcaact gccagacgag ttgaaacaac
     7741 aagtccagct gattttaaat gagagtgact ttatgaaacg ttccattatt ttacttccag
     7801 cctttttagc aaaaggtctg gagtttgacc gagttttctt gtgggatgta gatgcagaac
     7861 atttttcttc tcagcaagac aaattgatcc tttacaccat gtgtacacgt gcgatgcatg
     7921 aattgaccct ttttacctcc aataatgaaa gtcctttgtt aaacaatatg gatatttcat
     7981 cttatgagaa aaaagtactg taagtaaaaa gacaactgct atcattaatg ttagcagttg
     8041 tctttttatt tacaataata attgcagaaa aagtaattca atcatttaag gtcatttatt
     8101 ctatatataa atccaaatct gtttcaggat attttaattt gacaagcgaa ataatcattt
     8161 tcagttcttc catgttttct ggatattctg ggtcaaatac cttgctatga cggccaatcc
     8221 cgccattgtc gatcaatcgg taaattcgat tccattcaat gaattggtca attgattgga
     8281 aattgctgat tggatagccg ccacaatcca aaatctctga tacacgaaat gctaggtatg
     8341 cactatcgat cacattattt tttttcgtgt ctatcttctc atttctttcg ataagaattt
     8401 tttcaggacg atgcttcaag ctccactcta atagtagaaa gaaagcctcc atccgatact
     8461 cttcttcaaa taaccgaaag gctgaatcag aacgacgaaa aagcagcgga atcagataat
     8521 tttgtctata aatcagcatt ggtgcgcggt ccaccataca ctctaaataa cggttcagat
     8581 accctgtacc gacatagttt cctaatcgat agccttcaac gccgaatctt gcgtattttt
     8641 gcgctaattt tgaacaatca gttacgttca cagctaactc ttctactttg cggtaaccgc
     8701 ttaagatacg ttcaaaaggt tctaaagtga tttttgcttc catattcttc cccgtccatc
     8761 ttccacatac ttcatatcat ttcacatgat acttatgctc tcatcatacc acaggttgaa
     8821 ttagaaaaga aaataaatca cacaaaaaag caagacaatc tgttagtgag attgtcttgc
     8881 ttttcgaaaa agactgaata cttttcgtta aaactggttg cttagtcttc taatgccaca
     8941 ttatggaaca catgctgtac atcttctaga tcttccagtg catcaatcat tttttcaaat
     9001 gtttcttgat cttctggaga tagtgttacc tcgttttgag ggatcatttg gatctcagcg
     9061 attgaaaaat cagtgattcc tttttctttt aatgcttctt gtatactatg gaaatccgct
     9121 acttcaccgt aaacgatgat ttgtccttct tcttccatta catcgcgaac atcgatgtct
     9181 ttttccatta ggtattcaag gatctcgtca gcgtcttctc ctgcaaaagc aaagattgct
     9241 gtattgtcaa acatgtaaga aaccgctccg gaaacaccca tgttcccgcc atttttccca
     9301 aatgctgccc gtacgtctgc tgctgttcga ttcacattgt tcgtcaatgt atcaacaatc
     9361 accattgagc cgcttggtcc aaatccttca tagcgcaatt cagagtatgt ttcatctcct
     9421 gcaccttttg ctttttcgat tgctcggtca ataatatgtt ttggtacatt ataagtttta
     9481 gcgcgatcaa tgacgaaacg tagtttttgg tttgcatgcg gatcaggatc acctgatttt
     9541 gctgccgcgt agatttcaat cccaaatttt gcataaatcc ggctattatt agcatcttta
     9601 gcagttttct ttgctacgat atttgcccat ttacgtccca tattttcact tcgctttctg
     9661 atttgatagt ttcataacgc aaaaacgtcc tgttccatta tacttgtgaa tcacgattct
     9721 gtgaagcttt ttttctttct tccttcattc ttctcatttt tagtcaatta tctatactcg
     9781 gattgggatt tgcccgaaat tctgttccgg aatattgcct cccaattgat agatttgatc
     9841 acttctaact aacagttccg cttcttgtgc ctcttttttt ccgattcggg aataaataga
     9901 aatctctttt ttttctttta agaatcttct tccaacatcg gtaaatccaa gtagtcgaag
     9961 ataattttta ttttgttgga caggaatctc ttgctttttg atattcagca agacataaca
    10021 agataatcgt tggatccgtg tccatgtata tctttttgtt tttacctttg acacaaaatc
    10081 ctcaaaacta tcagcagttg cagctgctgt tttcatgcgc gattctattc cttcggtcat
    10141 ctgatagata tctgtcagtt ccagcaaagt agaagataac aaccgataac gcaaatacgg
    10201 ccaataagat tcccaagtct gcagcgaata agttgaaaga tcttcttctg tctgaggcgg
    10261 cacaagtcca gctattcttt ttccttcttc taacgcatgg cgaatggctg ttgcactggc
    10321 tatcctctga tctgtgatga ttttttcatg atagcctgca cttttacgtc ggatcggatg
    10381 taattccata gggtggacat acttggcatt ttcctttgca taacttaatc ccaagatatg
    10441 atttggcgaa gaaaaatcaa gcgtaatatc gggatacaga ctgcgaaaaa cctcagtcat
    10501 tttttgcgga taactatacg tttgatcaga cagttcttga aatgcctctt ctatcctatc
    10561 ttgattctct tggacaaagc gtccgaaact gctgtaatca aacgaagtct cttcttctgt
    10621 tccaaaacac aaactgtcac agtccagtgt ttgcaagatt tttactgcac ctttagcaaa
    10681 atagtcagct gactgaaccg cccattcgac gggaagctcc actactaaat ccacaccatt
    10741 ttgtaaagct tcattcgcgc gatgccattt atcgatgata gccggttcgc ctcgttgcaa
    10801 aaaattcccg ctcattacag caatgacgac ctctgctcct gttgtttttc gtgccatttc
    10861 cacatgatag cgatgtccat tgtgaaaagg attgtactct acgataatcc cgcagctttt
    10921 catgcgcatc ctccttcata gttatcgata aaaaagaaat agagacaagt aaaaaaaggc
    10981 aaaaatcgga aaaaataccc gaactatata aactattctc gcaaacacaa tacttctgcg
    11041 acgaaaagct gcactgcaag agcaatgcct atatcgttcg gatatataat ttatgttgaa
    11101 gatttattct tttcttgtta actcgagcag gcaaaaccgc tagtctttgt atgctacaaa
    11161 gaaccagcgc tttgatttct ctgatgctgc ttcgtctgta aaatcagaaa atgcttcgac
    11221 tttcgaaaag ccgctgtttt ccagcattct taaataactt tccaatggat aggtacgctc
    11281 ttgatgtagt tcatcttcac gaataaatcg accagaccct tcttgttctt caacgaaaaa
    11341 ggtaagaaaa tgttcgatgc tgtgtttctc gcttcctgga taactatccc acaaaaaagc
    11401 aaaattatcc ccttgataat gatagctata ttctggaaaa atttcatcta cttgataggt
    11461 ggagtgtacg tcaaataaaa atcggccatt ttcttctaac gcttgataga cttcatcaaa
    11521 cacttgctgt acctcttgtc tatttttcat atagcacagc gaatcagaaa aacaggtaat
    11581 tgcctgatat tgtccgattt ctgataaatc gagcatattg ccttccacaa attggatcga
    11641 tgcgtcttct tcatatgctc gctggctggc aatcatcaac atctcttctg aaaggtctaa
    11701 ccctgtcact ttatatccat cttttgcaaa ggcaactgct aatgctccag taccgcatgc
    11761 cagttccaaa atattttttg tgtcttcttg taaatgacgt ttcgaaaaag ctagccattg
    11821 ctgataaagt gtttcgtcca tcacttcatc gtaaatgaaa gcaaatgttt cataagccat
    11881 atgttaatcc aaccattcac taagatcgac tagcggagca tctgaccata gtttttccag
    11941 attatagaaa cttcgttctg gtgcatggaa aacatgtacg atcacatctc caagatcgat
    12001 caatacccat tttccgcctt cttttccttc aatacgtttt acttcatatt tgttttcttc
    12061 ttctttatca atgatttctt ctgtaattgc gttgatttga cgttcgctat ttgctgaaca
    12121 gatcatgaaa taatctgcca acaaggaaac atttcgaatg tctaaagcga taatgtcttc
    12181 tgcccgtttt gaatctgctg cttcaaccgc aatttttaat tgttctttac tatctatgat
    12241 gatttcctcc taatatgagc agcttatttt tttgctaccc agtaattata tgtttcgatt
    12301 gtttttggat aaatctgttg ttcttgcgca agcaaatggg ccaatgtatg ttttgtttca
    12361 aatgctacag cttcgtctag atcagcccat gcaatggctc gtgcatcttg taccccagga
    12421 aaatctcgac ctggttcaat atagtctgct acataaatga ttttgtcaag gagactcatc
    12481 ttagcagccc cagtcgtatg cacccggatt gcatgaagaa tttctacatc ggtgattcct
    12541 aattcccgct ctacaaacga agcgccaaca agaccatgcc agattgcatt attataattc
    12601 aataactctg gatcaaaacc gtctcttacg attaccattt tgaactcctc atctggtcgt
    12661 tcttttgcat aatcatgtgt caatgcagca atactagctt tttcaggaga agcaccgtat
    12721 tttttggcaa gagccacggc tgtttcttct actccaagca catgcttgaa gcgttgttcg
    12781 ctcattctca tctgtatttt ttgcatcagg ttttctctag aataagcagt atattcatta
    12841 ctatagtcca tattcataca acccttcatt ttgaatataa tcaattactt tatctggaac
    12901 aaggtagcgg atagaacagc cttctttgat cttttgacgt attttcgtgg aactgatgtc
    12961 gatctcaggt acatctaccc aaattacagg atatggagta tccgttgtgt atcctggtcg
    13021 acgtataccc acaaagttga ccatagaagt cagctcatcg attttatacc attttggcaa
    13081 atattctacc atatccccac cgataataaa gtaataatct gtatccggat tgttttgcgt
    13141 caattccttc atagtatcat aggtgtaact tttcccacca cgagctaatt caatcgtttc
    13201 aatctgcaaa aaaggattgt cttccacagc taattccaac atgttgagtc gatgttttgc
    13261 atcaatcgtc tgtttctcat caacatgagg tggctgataa gaaggcatca aaaatacgcg
    13321 gtcaagacct aaattccggc cagcttgttc agccatcact aaatgtgcaa ggtgaacggg
    13381 attgaatgtt ccgcccaaga tccctacttg ctttttcttc tctaagaatt gaggcatttc
    13441 ttcaggaaat aattgtgaac gaacaaatgt cttagcttgc gtattcatca tggtcactcc
    13501 ttatattgct tttacttctt ttgatagcct ttgatacttt tcttttgtgg aaggtttgta
    13561 taatacaata acacgtccaa tgatttggac gatttcgcaa tctatttctt tttctaatac
    13621 ttgagctgct tcttctgcaa tctcatctgt attttgaagt aacgatactt tgatcagttc
    13681 tcttttttct aaagcttctt caatttgaac gatcattgct gaattgatcc caccttttcc
    13741 gatttgaaaa atcggctgaa gatgatgcgc tttgctacgt aaaaaacgct tttgttttcc
    13801 tcttaaactc ataattttcc ttcttcctta aatcaatgct ttgcgtttca atacatctac
    13861 accctttggc gcccagcccg caattactac tggcgctgtt acagtgatcc agcctagacc
    13921 ggcaaaaacg atgtctgttt tttctttcac agaaaactca aaacgaacaa gctccggaaa
    13981 tgcctcgact tcatcaggac gaggaggctg taataatcca cctacatgtt tttgataaaa
    14041 ttcgtctgct ttttccagtt tcgttcgatg aatatttaca tcatttgaca cataagcaat
    14101 aaatgaagca cgattgccgc tgataaaatc aaatcttgca agtccgccca agaaaagtgt
    14161 ttgcccttca ttcagctgat aaactttagg tttgatttct tttaacggtg caatgatccg
    14221 caaatctttt ttacctaagt agtgcgccat ttgatggcga tggataattc ccggtgtatc
    14281 aatcaaaaaa tgcccgtcat ctaaaggaat ctcgatttta tccaaggtcg ttcctggaaa
    14341 ctgcgaagtt gtgattacat cttgtactcc cgctgtattt ttgatgattt gattgataag
    14401 cgtcgatttt ccgacatttg ttactccgac gatatagaca tcccgtccat cgcggtattc
    14461 ttcgattttt tctaatagtt ccgtcatctc atgagatttc ttagcactag ttaataatac
    14521 atctactgga cgaattcctg cttcgtaagc acgttccttc atccattgtg ttaatttagt
    14581 ttttttcaat gatttaggta atatatccac tttgttccca actaaaagta ctggattgtc
    14641 accgacaaaa cggtgtagtc ctgggattag tgaaccattg aagtcaaaaa tatccaccac
    14701 attgacgatc aatgcatctt tctgccctaa ttcattcagt aagcgcaaaa agtcgtcatc
    14761 cgtcaatgag acatcttgga tctcattata atggcgtaat ctgaaacaac gctgacaata
    14821 gacttccccg gaagctaaac ctttttccaa agccgtttgc ggcgtgtatc ctaattcacc
    14881 gggtttgttt gtttgtataa cggcaccaca gccgatacat tgtaattctt ctgtcattcg
    14941 attccacctc gccagcccat atcagggtgt tttgctaata gataggccat aattcttttt
    15001 tcccaaaaac gattaaattg tgtcttccaa ctatctgttg cgataatggg ttttacaagg
    15061 atgctacgta tccctgcacg attggctcca cgtatatcag tcataatctg atcgcctacc
    15121 attactatct catcatctgc taaatccaat tgtttctttg ctatgttgat ccctcttgct
    15181 aaaggtttca ttgctcgtgc aacatacaaa agatcaaatt tttcaatcgc tcgcgcgaca
    15241 cgttttgaat tattgtttga aacaacaaca acagggattc ctgcattttt catttctaaa
    15301 atccaagtaa gcaactcttc tgttccatct ggattattcc atgcaatcaa cgtattgtct
    15361 aaatcggtca atactgcttt gatgcctaga ttctttaatt gggcaggtgt aatctgatag
    15421 atggcttcta ccatccatgt tggtttgtaa tttgaaaaca tgctgtctcc tcatctgcaa
    15481 aaaatgaagg agcacataaa gtactcctca accccgtatt atactgcata tcagcaaaaa
    15541 aaactacctc tatactcgtt cgtctttcag aaaaagcatt tctttacaaa atgaccaaaa
    15601 ataaagattg atcacagaaa aatttagaaa caaaaaacaa ctaagcgagc aagaccattc
    15661 tttactcttt gcttagttgt taaacaccta atattggcgg aacctcttgt atcgtttttc
    15721 cagtaattca tgctggtcga atcgaacaag ttccgtcaat ctttcaatca acgctttttt
    15781 cataatgtgt gcgactttat atcgtggcaa ctgctcgccg ttgaacgttt caggaataac
    15841 tcgatcaacg attcctaact cgcgtagttc tggcgcagta attttcatca actcagctgc
    15901 ttctgcggcg cgactaccgt ctttccacaa aatcgacgca aatccttctg gagaaagcac
    15961 agcataaatc gtttcttcca gcatccagac ttcatccgct aaacctagag caagggcacc
    16021 gccacttcca ccttcaccaa tgatgatggc gatgatcggt acctttaaat cagacatttc
    16081 gagcagattt ctggcaatag cctctccttc gccgcgctct tctgctccta caccgcaata
    16141 tgcacctgct gtattgatca atgtaatcac cggtctattg aacttttccg cttgtttcat
    16201 cagtcgtaaa gcttttcgat agccttcagg atggggagaa ccaaaatttc tgcggatatt
    16261 ttcctgcaga tcccgtcctt tttgaatacc gatcactgtt accggtttgc catctaatcg
    16321 agcgattcca ccaacaatcg cttcgtcatc tgcaaacaaa cgatcaccat ggcattcctc
    16381 gaaagaatcg aagatctctt caaaaaaatc caagcttgtc catcgttctt tagctcttgc
    16441 taactgaacg acatcatgtg ctgtcttatc cacgatctat ccatcctttc tgtgtatgca
    16501 attcaagaag cgtatggatt ttctgcttca attccatgcg gggaacaatc tgatcgacaa
    16561 aaccatgaga taataagaat tcagcctttt ggaaatcttc tggaagttcc tgcttgatcg
    16621 tctgttcgat gacgcgtctt ccagcaaaac cgatcaagct ttggggttct gctagaatga
    16681 tatcgccttc cattgcaaaa ctggcagtta ctcctccggt cgtcgggtcc gttaaaacag
    16741 ttagataaaa aagaccttca ttgctatgcc gtttgacagc agcagagatt tttgccatct
    16801 gcattagaga aaagattcct tcttgcatcc gtgcgccacc tgaagctgtg aacaagacga
    16861 ctggaagact ttcctttgtt gctcgttcga ataatctggt gatcttttct ccgacaatcg
    16921 ttcccatact tcccatgata aaattaggat ccatcactcc aataatgaag ggaatccctt
    16981 gaatggttgc tttaccagtg aggactgctt catgaagtcc tgttttatct tgcatttttt
    17041 taattttttc cgtatattcg ggaaatgcta gcggatcttt ggttacaaga tccgtatccc
    17101 attcttcaaa acttttttca tcaataatca aagctagacg ctgccatgca ccgattcgaa
    17161 aagcgtatcc gcaatgaggg catacttttt cttcaccgat gtctttcgta taaaggatat
    17221 gtttgcaatt tggacacttt gcccacatgt tatcaggaac agatggcgag ttagcaggtt
    17281 tgctctctct attaggattg atccgaatat atttcttttt cttaaacaga gccatctatg
    17341 cgcctcctat ctccgtttct ggtgtccaat tcggtaaaaa ttcttcttgt aaaaatgctg
    17401 tgctgtaatc acctgctatg actgcagggt gactaatcaa atccatctga aattctgcgt
    17461 tcgtgatgat tccttctgtg ataaattcac ttaaggctcg ctgcatcttc attaatgctt
    17521 caaaacgcgt atttccatgg acgattattt ttgcaatcat tgaatcataa tatggcggga
    17581 tcgtatatcc cgggtaaact gcactgtcta cccgcagtcc catcccacct gctggaagca
    17641 gtaagttttg gatcttccct ggagaaggag caaaatggaa agcaggattt tctgcattaa
    17701 tccggcattc gattgcgtgt ccttggaata ctacttcttc ttgacacaca ttcaaaggct
    17761 caccggctgc tatctccacc tgttttttta ctaaatcgat tcctgtgacc atttctgtta
    17821 ctggatgttc cacttggatt cgagtattca tttccatgaa ataaaaatcg ccttcttcat
    17881 ccatcagaaa ctcgatcgtt ccggcatttt cataattgac tgctttagct gctcgaacag
    17941 cagcgtctcc tagtgcttct ctttttgttt gtgagatcac tacagaagga gattcttcca
    18001 gtactttttg attattacgt tgcaaagaac aatctcgttc tcctaaatga atgacattgc
    18061 caaaatgatc acctaaaatc tgaacttcta tatggcgagc aggataaatg attttttcca
    18121 aatacatatc atcatttcca aatgccgctg ctgcttcttg ctgagctgaa aaaaaatgct
    18181 gtgggagctc ttcttttgat tgaactttcc gaatgccttt cccgccacca cctgcagctg
    18241 ctttcagcat cactggataa ccaattctgt ctgctatttc caatgcttct tctactgtag
    18301 ataatacacc agtacttcct ggaatgactg ggacatttgc ttcttgcatc aattgacgcg
    18361 cattgatctt atttcccatt gcatcgatcg ttgcactttt aggaccaata aatgtgatat
    18421 tgcactcttc acacatggag gcaaatcggc tattttcaga taaaaaacca aatcctggat
    18481 gaattgcttc ggcttttgtc acgattgcag cgctcagtac ttcctgaaca ttcagatatg
    18541 aatcaacggc ttttgccggg ccaatgcaga ttgcttcatc tgctaactgt gtatgaagtg
    18601 cttcggcatc tgcttctgaa tatatcgcta cggtttggat ccctagttcg cggcatgcac
    18661 gaatgatacg tacagcgatt tcaccgcggt tagctatcaa tactttagaa aacatatttc
    18721 acctatccaa tcataaaggt taattccgct tcggctactt ttttaccgtc tactttagcg
    18781 attcctttgc ctattccggc tgaagctttc actttcaata tctcaacttc aaggtataag
    18841 gtatctcccg gtgtaacttt cttacggaat tttgctttgt ccaatccgcc gaaataagcc
    18901 gtctttccct tgaattgttc aagagaaagt aatgcaactg ctcctgcttg agccatcgct
    18961 tcaacaatta atacccctgg cataacaggt tcttctggaa aatgtccttg aaaaaagggc
    19021 tcattgatcg ttacattttt cttagcaacg atccgttctc cttcaaccat ttcttccact
    19081 cgatcaatca aaagcattgg ataacgatgt ggaatgattt cttttatttc ttgtatgttc
    19141 attgatttcc ctctttcctg ctttgcttat ttttgctgaa tcctaaagag tggctgtcca
    19201 tattcgacaa ctgactcgtt ttctacaagg atttctgtga tcactccgtc ggcctcacta
    19261 gttatctcat tcatcagttt catcgcttca ataatgcaga taacttctcc tttggcaact
    19321 tgatcaccta cttttttgaa agctggtttg tcgggcgccg gttgcagata aacgattccc
    19381 acgattggcg aaacaacctc gattccatca aatactgccg attctttttc tttcattgtt
    19441 tctggagcag ttgttgcttg ttcaggtatg acattgactg gctccgaaac tggcaacgtt
    19501 tcgtttgttt gaaccatatt catgcctcga cttgttttat ttttattcat atacaattca
    19561 aattgacctt cacgcaaatc gaattccgtt agcgaggatt gatcaaattg actgactaat
    19621 tctctgattt cattgatatc caaaattatt cctcccagcg tttcatgcac agaaccgcat
    19681 tatgtccgcc aaaccctaat gaattactca ttgcataagt aaaacttgca ggtttgcttt
    19741 cgtttttgac aactgtcaag tcaatctcag gatcttgttt ttctacattg atcgtaggtg
    19801 ggataaattg atgttctaat gccagcaaag ttgccaaggc ttcgatcccg ccggctgctc
    19861 ccaataaatg tccagtcatc gatttcgtgc tgctgacgta agtatctctg aaattttcac
    19921 ctaatgcgat ttggattgct tttgcttctg cctggtcatt ggctggtgta cttgttccgt
    19981 gagcattgat atatccgact tgttccggct gtacaccagc ttcttccatc gcaagcttca
    20041 ttgctttaga cgcaccagaa ccatctggag taggagctgt catatggtaa gcgtcacagt
    20101 ttgcaccgta tccaacgatt tctccataga ttttggcacc gcgagcttgt gcatgttcta
    20161 aagattcaag aactagaaca cctgctcctt cacccatcac aaaaccattc cgattttcgt
    20221 caaacggaat cgaaccacga ttaggatcag ttgattctga gagtgctgtt aaagctgcaa
    20281 atccagcaat ccccatctca caaatcgttg cttctgttcc tccagcaaga atgacatcag
    20341 aatagccatg tttgatgtta cggaatgctt ccccaattga attcgttccg ctagcacaag
    20401 ctgttacgat agctgtacaa ataccttttg cacctacgcg caaagcaata tttccagctg
    20461 ccatgttggc aatcgccatt ggtacgaaca ttggagaaac tcgttttgca cctttttcat
    20521 gtagacgaat aacttggttt tcgattgttg gaagaccacc gatcccagat ccgatgatga
    20581 cgccaaaccg gtcttgattc attttttctt tatctaaacc gctcatctcc attgcttcta
    20641 aagcagcgta gattccatag atcgaaaaca tatccattcg tttgctatct tttttaataa
    20701 aatatttatc gtaagggaaa tctttgactt cacccgctaa ggtaatccct gtttctgaag
    20761 catcaaattt agtgatcggt gcgatgccat tcgtcccctc ttttaagcta ttcaaaaagc
    20821 tgtctgcgtc atttccaata ggtgaagtga ctccatagcc agtaattacc actcgattca
    20881 tttgtttgct ctccttttct tatccgtgca tgaccaatcc gccatcgaca ttgatgactt
    20941 gtccggtgat atatggattt tgtgctaaga aaactgctgt ttgtgcaata tcttctactt
    21001 gtccgaaacg ctgcatcgga atttgctttt ccgcttgttc cttgactttg tctgctaaaa
    21061 cttccgtcat atcagttgtg atgaatcctg gcgcaatggc attacatgta atgcctctag
    21121 ttgcagcttc tcgtgccaca gattttgtta atcctactac gccagcttta ctagctgcat
    21181 aatttgcctg accaatattt ccaatcaacc cagatacact agagagatta atgatggccc
    21241 cttctcgctg cttcatcatt tttttcaata cgtgctgcgt catattgaag gttccaatca
    21301 aattgatatc aagacatttt ttgaaatctt ctgcatccat tcgcatcaca agtttgtcat
    21361 ttgtgattcc ggcattgttt actaacacat ggatcgatcc aagcttttct tctgcttctt
    21421 tgatcatttg tcccgctttc tcataatcag agatgtcacc ggaaactcct acgcatttta
    21481 caccgaatgc ttcgatttct tctatctttt cttttggaat ctctccgcga ccattcaaaa
    21541 tgatatttgc tccagctttt gcaaaagcta aggccatcgc tttgccgatt cctcttgtac
    21601 tacctgtgat aaatacattt tttcctttta catccataac gttcctcctt atagtattgc
    21661 tattgtttca tcaaatgtct gcttattctc aacacgcaga actggtattg ttttatcgat
    21721 ttttttcata aatccgctta atacttttcc ggggccgact tcgatgactt gttcgatgcc
    21781 gattgttttt aacttatgga tactctcata gaaacgaaca ggttgcatga cttgctgttc
    21841 aagtagtccc gcgattgttt ctttcttcat tatttccgtt gttgtgttgc ttatgatagg
    21901 aaaagaaggt tcagagaatt gaatctgact taggtccttc gccagttttt ttgctgccgg
    21961 ttctaaaata gctgtatgaa aaggcccgct gacatttaga gggatcattc ttttgaaccc
    22021 tttttctttt aatagtaaaa cagcttcgtc tactgctttt tcttcgccac caatcacgat
    22081 ctgctgaggt gtattataat ttgcaggaga tacgatgccg tacttgctag cttcatgaca
    22141 gctttcctcg atcgtttcaa tcggcgcatt catcactgca accattttcc cgcttccagc
    22201 tggggcagct tctgtcatat aagcgcctct ttttgctact aacgcaactg cttcagtgaa
    22261 ggatagcgca ttactagcta ctaatgccga atattctcct aaactcagtc ctaaagctgc
    22321 atctgggatg attccatgct ccttcaataa gcgataatac gcgatgctga ctgttagaat
    22381 agctggctgt gtatattgcg tctgatccaa acgttcattt tctgtaaagc aaagttcagc
    22441 catatcgtag ccgagaatct cacttgcttc atcaaatgtc tgctttacaa cggcttcttc
    22501 atataaatct tttcccatac cttgatattg tgcaccttgg ccactaaata agaatgctgt
    22561 tttcatgttt ttctccaata tatccagaat atatgtttga ttcttcctat tcaaaaaggc
    22621 cgagacattc ctatttcagg aaatgtccca gcccccaacc taattttaat gattatgcag
    22681 tttgtttttc tacgtaagtc actaaatctt gaaccgtttt gattccgtct tctgtttcga
    22741 ttttcacgtc aaattcatct tcaatttcat tgatgatttg gaataaatcc aagctgtcag
    22801 cttctaagtc ttcttggatg tcagtagtca atttgatttc ttcagtttct tttcctaatt
    22861 cttctgcgat gatttcttga attttttcga ataccataat aatatattcc tccgatattg
    22921 tttgcttttt atttttataa tttaacagtc tacaactcca tgagaatact tccccatgtt
    22981 aaacctccgc catagcctgt aaatattact ttctgctgtt ttcccaaggt gatctttcca
    23041 ctagaaactg cttcatccaa taagataggg atgcttgcag cagatgtatt cccatattta
    23101 tccatattgg tcagaaactt ttcttgcggc atctttactt ttcgggcaat tttctcaata
    23161 attctgaggt ttgcctgatg caaaagcaga taatcaactg gtttgtcttt catgacttct
    23221 tggatattgt ttgcaacgtc tcgtacggca aaatcaaaaa tatctctgcc agtcatttgc
    23281 aaataatacg aaccttctga atcttctgaa tagaacggat ttttattttg ctggtagcca
    23341 gcggtcaatg agctacttct ggtaccgtca gctgctaatt tttctttcag caattttttc
    23401 tgtggattcg cttctaagag aatcccacct gctccatcgc caaacaacac agcagtcgta
    23461 cgatcagacc aatcgattag cttagatagt gtttcaccac caatcactag tcccttagtt
    23521 gagccgcagc ggatcatttt ttcagccatg cttaacgcat aaacaaatcc tgagcacgca
    23581 gcactgatat caaaagcgat agcatgagtt gctcccaatt tcccttgtac ttgtgctgct
    23641 acagatggtg tcgtgtaatc gggcgacatt gttgctacta aaataaaatc caaatcttta
    23701 gggtttagat ttttctgttt tatcaatttt tccgccacta aaatgcataa atcagaagtc
    23761 tcctgatttg ttacacatct tcgttcacga atacccgtcc ttgacgaaat ccattcatca
    23821 gaggtatcca tcatcttgga aagatcatta ttagtaataa tcttttcagg aaggacgctg
    23881 gctgttgcag taatcattcc aaattgttcc attaaatatc ctcacttata gtcttgcaag
    23941 aagtcgtgca agtttttcag tgcatccagc aaggcatgct gttcctccgt agccattccg
    24001 tctaagatgt tcttgaccat ttcacgatga aaatgctgat ggacccgaaa tagtaacttt
    24061 ccttttttcg ttagtcccaa ctttacaacg cggcggtcat cttcactgcg gatacgttcg
    24121 acatagcctt tttttactaa cttgttaata gcagtggtca aggtcccaac agtaattgat
    24181 agttctttgg ctacttctga agttgttttt ttcttgtaca tcccgattgc ctcgatcgtg
    24241 tgcatctctg tgattgacag atctttgaat tgagattttt tcagctcaga ctcttcgatt
    24301 gtcaaaatat cattgaagac actaacaaga taatcattta ctgtttttaa atctggttcc
    24361 atgttccacc gtccactaat tagtttgatt atcaaatctt ttgatgttca aactatatct
    24421 taactttttt caaaatgcaa ccttaaaaga tcattttttt actatatgag ctttttttaa
    24481 gattttactc atttaaaata actgataaat cagcatttat aatttctttt attagaaaaa
    24541 tcatctatct cacatatttt gattatcaaa gtattttctg tgaacagaac tatagaattc
    24601 cttaaaactt gtccattatt tcaaaatttg ttatagtctt tttattcaaa gcgtaaaagg
    24661 agatcctatg ttaaaagaaa aaatgaaaac tctccccatg ctgccgggtg tctatcttat
    24721 gaaagaccgt gatggtaagg tcatctatgt tggtaaagca aaacggctca aaaatagagt
    24781 aagcagctat tttcatcaga ataaacagca ttcaaaaaaa gtattacgta tgattcatca
    24841 tataacagat tttgatttcg tcgtagtaga cacggaatta gatgctttat tgctcgagtg
    24901 tcaattgatc caacattacc gtccttttta taaccgacaa atgaattatt tcagtaatta
    24961 taattatgta catattacca ataagggatt tgtattaaca gatactccta cggctcgaac
    25021 atacgggcct tttcgtctct ataaaaaaat gccgtctatt ttgcgtataa tggaagaaac
    25081 ttatcaaatg ccttggttgt ctgaaattag tttgttagct ttgcgagccc agcttcctga
    25141 cctacaggaa atgacttttg aacagaaaaa aaaggaactc caagggctgt ttcaaggcca
    25201 aaataaaaag ctactaactt acttgaaaaa aagacaacaa catttcatct atcagttgaa
    25261 tttcgaaaaa gccggtatgc ttcaaaaaga tatcgaatta gttacttatt ttattagacg
    25321 gatccaggaa caaaagcatt ttttaagaac accatcgctc accttcagca tgccattagc
    25381 agcagatgag agtcagaaaa agcactacct cgtttgttat ggtcaacttg cagaaacaat
    25441 gattgcctct gctgacgttt ctcctgactt ctattatgaa aagaaagaag ctcatttatc
    25501 tttgaaacgt caattgtcaa aagaagaaat cgatcctgta caaatcttga tcagttaccg
    25561 caaaaaatta gaaaaagaac agtctgaaat tgaactgtta aacaaaaaag aagctgaaaa
    25621 gcaactaaat tagttgcttc tcggcttctt ttaggcatct tcaacttcaa atgtcaatta
    25681 tcctaaaatt tattggatta agtcatagat ttccatcgct acgatatcga tattatcaaa
    25741 ttcgtattgc tgatgagtat ctgtttcagt taattcaaat gtatcggtcg ctttatcata
    25801 agttactgta cacttctcta cgccttcttt ttcaaaacgg cgaacttgca gttcattatc
    25861 tgctgactcg accatagcct ccagtcgttt tatgattgcg actaattgtg aatgtgtcat
    25921 cggaggtcct ccttttctta tttctgttat attgtatcaa aagcatagcc tacttgcatt
    25981 gattttctct aaaaaaactc gttttttatg attttttttc tggtattttt ccttcaggcc
    26041 accaaagttt gatcaaagct tgggttccgt cattctcaaa acctttatct gccaactctt
    26101 catatagttt caatgcttgg gtagttgctg gcaatacaag gtccattttt tctgcttctt
    26161 ctaatgcaat ctttaaatct ttgataaaat gtttgacaaa aaaaccaggt gtgtaatctt
    26221 cttttaaaat acgaggagaa taattgctta aagaccagtt agctgcactt ccacctgaaa
    26281 gcgtctcaat cactttcttt aaatcaagtc cgtttttttg tgcatagaca agcatttccg
    26341 tcattcctgt catcgtacct gcaatcatga tctgattagc catttttgta tgctgacctt
    26401 tcccagcaga accatgcaat gtaaatgtcg taccaaattc tttgaataaa ggcagtactt
    26461 gatcataaac ggcttcttct ccaccgacca tgatcgtcag tgtaccattc tttgctccta
    26521 agtcaccacc ggataccggt gcatctaacg catctgcgcc tttttctttt gctgtttttg
    26581 caattttttc tgccaggctt ggtgtacttg tagtcaagtc aactaaaata tgtcctgaga
    26641 tatctgcaga aaaaatcccc gactgtccat agtagatttc ttctacatct ttggggtaac
    26701 ctaccattgt aaagagaata ttactttgtt ctgctaccgc ttttggtgta tctgcccaga
    26761 tagctccttc tgttactaaa ggatcagctt ttgcttttgt ccgattatag acagctactt
    26821 cgtgtcctgc ttctagtaga tggcgtgcga cagcacttcc catgacgcct gttccgataa
    26881 aaccaagttt cattttttcg acctcctaaa aatcaaaaat ccttgcttct atgctagtat
    26941 acgctagaaa caaggatttt ttcataaaaa atgtttgaat tttatctttt aaatgaattt
    27001 aattttattt tgattcgttc aatcgagtct tcttcttctt ttcttcgcat ctcttcttca
    27061 tgataaacaa ccatgtcttg ataaaattcg atcatagctt cgccgaaatg tgtagatgaa
    27121 atatcataaa gtttagcttc taaaactttt ggatctttag gaacttcact ggaaatataa
    27181 tcaataagtg ctggtgcaaa gtcttcgtcg gtttcaaaag ttttccctaa tgaaggatga
    27241 tcgaacaatc ggttcaaata agcatttcct tccacgacac aaggtgttcc ggctgccatc
    27301 gcttctgtat aggtaagccc ttgtgtttct gaagtagaag cactgacaaa ataatctgcc
    27361 gctttataat aaagtgctac atcattgttg tccacttctc ctgtgaactg cacaaattct
    27421 tctaactgca gttctgagat caattcctct aactcttcta cataaggtcc ttttcctacg
    27481 ataactaatc tggcgttagg ataagcggag atgacctgag gaaacccatt aatcaaggct
    27541 tggatatttt tctcataaga aatcctgctt aaagaaagaa tcatcaaatg gttttcctga
    27601 agacctagtg actcccttaa tttgctgata tcctgctgag tgatatcaga acgtttgaat
    27661 ttttcaatgt cgataccagt aggaatcacg cgaagcggtg ctattacacc atagctacgt
    27721 aatgtatcaa taacacgttc acttggacaa actacacctg tcgtatgatt tgcaaataat
    27781 ctagacaagt attttacatg ggattgcctg atcacttttc ctttaccgat ataatgaagg
    27841 tagtcttcat acatcgtatg gtaagtatgg atcagaggta ttttcaactt cttagctacc
    27901 atcttcccaa gtatccctgc tccgaattct gtatgggtat gaataagatc tagttctagt
    27961 tctttggcaa ccaaataagc ataccacatg cctctaacaa caactcttcg atccttgaaa
    28021 gaaataaatg gtacacttgg cattcgaatc acatcttttt ccaacttatc cgcattagga
    28081 tcggtcgttg taaaaatata gacttcatgc ccatgtcttt ctaattcttg ttttaatgtt
    28141 ttgatcgatg tagcaactcc gctgacttgc ggaaagtagg tatcggtaaa aaagccgatt
    28201 ttcatgtttt tcgcctccaa actagtcctt gacctgattt acttttttta atttgctaga
    28261 gactttttca ttcagtacac tttcgtatac atttttaagt tcttcaccga ttttattgat
    28321 acttcgctct tttgctgttt gataaccggc ttgtgtcgta ctcggtagtt cttgattggt
    28381 aatctgttgg atcagtcgga taaattcttc gtttgtcttc cccatatagc agttcttgct
    28441 atcttctaac cagccattat acactggaat atctcgaaca agtacgtttt gtttgcttgc
    28501 taaagcttct aaaacaacga tcccttctgt ctcttcataa gaagggaaaa agaatagatc
    28561 tgcacctgaa tacgcacctt ctatgatctc tccacgaatg taaccaggaa acaggacatt
    28621 ttcaggatga tcttctttta caattttccg gatgttccga ggaatcgagt acatgggaac
    28681 atgaccaaac caaataaatg tgtattcggg catcttctta gcaatttcta cgaaatcaat
    28741 gattccttta cgttcgaaaa acaaaccgac acaaatgatt actttttgat ccggagacag
    28801 tttgaaatat tctctgaact tttgttcttt cattggatca gggcgatatt tctctaagtc
    28861 gatcccattg gaaatagctt gaatcggcac acggatacta tagctttcca acaactgttt
    28921 tgaataaggt gttggcgtga tcagatagtc cgctttttgg tacaatccta ccagatattt
    28981 ttttacgata ggagaaagct ggttcgatcc gataaaggaa tttcggaaat cttcctctgt
    29041 agaatgcgca tgatagacaa ctttttttcc ttctcttctg gctttattga ccatattatg
    29101 actattgatt ccgtatgtat tgatgtgcag gatgtcataa tcttcttttt catctagtgt
    29161 ataagagata ccgacttccg tcagagcacg tttttgatga tcaagcgcac gcccgattcc
    29221 agattttgca agcatctttt cactttcaaa atataataat accttcacct tacgtccccc
    29281 ttcacttata tagtataaca tagcctacaa actgtcactc aaacttaagc cctattttta
    29341 tctattctta ctgacaaaaa cgttttctta aaaaagaaca aaaaaactgg cgtagctctt
    29401 ttacaagcca caccagcttt tgatacgttg tttattttac atattcatga acaagttcaa
    29461 cgacttcttc catcgtatcg cattctttca atgcacgatc agcaagttca gccattttcg
    29521 ctgtgtccaa gcgtttcatt aaactacgcg ttttaagaat agatgtcgca ctcattgaga
    29581 actcatctag acccatacct actagcaatg gaacagctgt ttgatctcca gccatttctc
    29641 cacacatacc tgcccatttt ccttcagcgt gtgctgcatc aattacattt ttgatcaaac
    29701 gtaaaattga tgggttatat ggttggtaca agtaagaaac gcgttcgttc atacggtctg
    29761 ctgccattgt gtattgaatc aaatcgttcg tacctacaga gaagaaatct acttcttttg
    29821 caaacttgtc tgctaagact gctgctgctg gaatctcgat catgatgccg acttggatcg
    29881 tatcagatac ttccttgcct tcactgatca atttttgttt ttcttcttca aagatcgctt
    29941 ttgctgcgcg gaattctttg agtgtagcta ccatagggaa catgatacgt aagttaccat
    30001 gaacagatgc acgaagcaat gcacgcattt gtgtacggaa catttcgtcg ccttgttcag
    30061 ataaactgat acgcaatgca cgatatccta agaatggatt catttcatga ggtaattgca
    30121 gatatggtag ttctttatct ccaccgatgt ccattgtacg aacaactaca ggttttcctt
    30181 ccataccttc taatacagct ttgtaagctt catattggtc atcttctgtt gggaagtctg
    30241 gagaatccat atacaggaat tcagtacggt acagaccaac tgcttctcca ccattattat
    30301 ggacaccaac tagatctttt ggtgttccga tgtttgcagc taattcaaaa tgcttgccgt
    30361 cagctgtgac agtttctgca ttttttaatt tttcccattc tgctttttgt gctgcgtaat
    30421 ctgcacctgc tttttcaaat tcagcttttt gttcatctgt aggatcgatg attacatcgc
    30481 cttcgatccc gttgacagcc aaaatatcgc cttctttgac tttagcagta atttcttttg
    30541 taccaacgat tgctggaatt tctaaagaac gtgccatgat agcagaatgt gaagtacgtc
    30601 caccaatgtc tgttacaaac gcttttacaa aattgcgatc taattgtgct gtatcacttg
    30661 gagtcaagtc atgtgcaaca acgaccactt cttcgttgat cattgatgga tttggtaaag
    30721 taacgcctaa taagtgcgct aaaatacgtt tagcaacatc acgaatatct gcagcacgct
    30781 cttgcatata agcattatct tccattgctt cgaacatacc gatatacata tccgttactt
    30841 cttttagcgc tgattcagca tttacgctgt tgtctttaat attttgcttg atttgaccta
    30901 ccatttctgg atctgaaaga accatcaaat gggcatcaaa tacttgcgct tctgcttcac
    30961 ctaagctttg cgctgctttt tcacgaattt gctgcaattc ttcagtagat ttagctaatg
    31021 cagcatccaa acgagcttct tcagccgcag tatcttctac tgttgcctta ctgaatgtta
    31081 aatccggttg aactagcagg taagcttttg caacggctac accgtcacta gcggcaatcc
    31141 cttttagcat ttcaaccatt attcagataa gccttctttc ttcattgttt caacgattgc
    31201 tgccattgca tcagcttcgt cagcaccttc tgcagtaata gtaacatcag aaccttgacc
    31261 tacacctaaa gacataacgc ccatgattga tttcaagttt actgatttac ctttatactc
    31321 taagtttaca tcagagttaa atttgcttgc tgtttgtact aatagtgtag ctggacgagc
    31381 gtggatccca gtttctgcta ctacgtgaaa ttctttcttt tccatattaa tcggtctcct
    31441 ttaagtgagt gttgttttta tgtgagggtt ttctttttta gtaattcaga gaatcctaac
    31501 aaatgccacc ctttcatctg taaagattaa catttttttt cgttagatac aacagttttc
    31561 attcaatttc agataaaagt attcaaatta ttccggattc tttttcatcc ttttcttcac
    31621 attttataac aaacgtgttt attttctttt tcttgtcgct ttctcttctc ctgacgttta
    31681 tcattctttc ctttgaccct ctttgttttc atatgaaacg aattacttgc ttcccttttt
    31741 atttttagta taataagagt caaaggtcag gaatggtcaa tagagatttc accttttcta
    31801 cctcataaat ctcttaaaaa actaggggtt attcttttac ctcatgaaaa acgagatgta
    31861 aaatatggat gtacccattt ttgtgaaagg acgtgaatga ttcatgcttt gtcaaaactg
    31921 cggcaagaat gaggcaacga ttcacttgta tgccactgtc aatggtcagc ggacacaact
    31981 cgattactgt cagagctgtt atcaaaaaat caaaaatcaa caaaatggag gtctgactaa
    32041 tatggcccaa aatgatccat ttggatttgg cagtttggac gatcttttcc gttccatgtc
    32101 tcgccaaatg caacagcaag gaaattatga gcaaacacca ccaacacaat ttggcggaaa
    32161 caacaacttc aatggtggtc agccacctca aggcaataca gaaggtttat tgggagaata
    32221 cggaatcaat atcacagaac aagcacgaca aggtgatatc gatcctgtga tcggacgcga
    32281 tgacgaaatc aaacgagtca ttgaaatttt aaatcgccga accaagaaca atcctgtctt
    32341 gattggagaa ccaggtgttg gtaaaacagc agttgttgaa ggtttagcac aaaaaatcgt
    32401 agatggtgat gtaccgcaaa aattaatgga caaagaagtc attcgtttag atgtcgtatc
    32461 tttagtccaa ggtactggta tacgaggaca atttgaagaa cgtatgcaaa aattgattga
    32521 agagatccgt caagcagaaa atgtgatcct attcatagat gaagttcacg aaatcgtcgg
    32581 tgctggttct gctggtgatg gaaatatgga tgctggtaat attttaaaac cagctttagc
    32641 tcgaggagaa ttgcaaatgg ttggtgctac taccttaaat gagtaccgca tcatcgaaaa
    32701 agacgctgct ttagaacgtc gtatgcaacc tgtacgggta gatgaaccaa ctgtcgaaga
    32761 aacgatcagt attttgaaag gtttgcaaaa acgttatgaa gactatcatc atgtaaaata
    32821 tactgatgag gccatcgaag cagccgcaac tttatccaat cgttacgtcc aagatcgctt
    32881 cttgccggat aaagccatcg atttgctaga tgaaacaggt tctaagaaaa acttgacgat
    32941 ccaaatcgtt gatcctaaaa caatcgagaa aaaactgcaa gaagcagaag aacaaaaagt
    33001 tttagcttct cgagaagaag atttcgaaaa agcagcttat tatcgcgatc agatcaataa
    33061 acttcaaaaa atgaaagaac gtcagctcac tgaagaggaa acacctgtga ttaccgaaaa
    33121 agatatggaa aaaatcgttg aacaacggac aggtatttca gtgggtgaat taaaagaaaa
    33181 agaacagaca caactgaaaa acttagcaga tgacttgaaa gctcatgtca tcggacaaga
    33241 taacgctgta gatcgagtag cgaaagcgat tcgccgaaac cgtgttggat taaacaaaca
    33301 gaatcgtcca atcggctcct tcttatttgt tggaccaact ggtgtaggta aaacagagct
    33361 tgcgaaacaa cttgcctacg aactattcgg ttcacaagat tcaatgattc gtttcgatat
    33421 gtctgaatat atggaaaaac atagtgtctc taaattgatt ggttctcctc caggttatgt
    33481 cggatacgaa gaagctggtc aattaacaga aaaagtacgg agaaatcctt acagtcttgt
    33541 cttgttagat gaagtagaaa aagctcatcc agatgttttg catatgttct tgcaaatctt
    33601 agatgatggt cgattgacag atgcacaagg aagaacggtc agctttaaag atacgatcat
    33661 cattatgaca agtaatgccg gaactggtaa agtagaagca aacgttggtt ttggtgcggc
    33721 acgcgaaggt gttactcgtt ctgtattgaa ccaattaaac aactacttta caccagaatt
    33781 tctgaaccgt tttgacggga tcatcgaatt cagtgcatta tcaaaagaaa acttgatgac
    33841 aatcgtcaca ctaatgctag acgatgtcaa ccaaatgctg gcagcacagc aacttcacat
    33901 cgaagttcct acgaatgtca aagaaaaatt agttgactta ggctatgatc catctatggg
    33961 tgctcgtcct cttcgacgca cgatccaaga acaaatcgaa gatggtatcg ctgaatttta
    34021 tcttgatcac ccttctatcc atgagttgaa agcaaaactg gataaagatg gaaaaatcat
    34081 cgttacttct aaaccagaac gtttggctaa agaatcagcc gaagaaacgg ctgaataaat
    34141 ccagttttat agcgtgagac ggtatttctt tgagaaatgc cgtctcattc ttttttcaga
    34201 aaagtcaaaa tactgttcat tttataaaaa agaaattata ataagagaaa caagcaatta
    34261 aaaatacata aaagaggtga gcgccatgaa attggtaaat gtaacaaaca gccattcccg
    34321 tcttgtatta aaccagcttg aaaacactga tgcccatcta gtcaaggtct acacagccgg
    34381 aaataccact attgtctaca ctgaagcccc tgaacataat gaaattctgc tgatcaatga
    34441 caaacgtaaa atccagccga aagaaatcga agatgctaaa aattatttct tagataaaat
    34501 caaagacgcc gtttaccacg aggatgaaat caaagtaatc gaattggcag gccttgttga
    34561 aatctcgatt ccaaaacatg aattaggcgc tacattagcc gtgtaaacaa attttgaaca
    34621 taataattaa agagcgtggg acaaaagtaa agaacacttt tgtctcacgc tctaaacacg
    34681 tataaacggc ggaagcagaa gcaactcctt cggaaataag ctaaaattca cgaaaattgc
    34741 ttttcaaatt tttgtgaatt ccagcttatt tcttggagtt aaacgcttct gtctcagcct
    34801 ctttttcttt ctagcttttt gatttttctc ttttcttttg tacttttctc ttttcatttt
    34861 cagttctacg cgtgtcttta tttttaactt tttcctcttt atggatgatt gatcgtactt
    34921 tttgtgcaat ttgctcgttt ttgtcccagt cttttacatc taataatcga cataatcgta
    34981 acatctcttc ttttttctgt ttttttcttt cacgtctttg ccattctgtt tccatgtgtc
    35041 acactctcct ttctttaatc atatgtacgc aaaataattt tt
//
LOCUS       DADVXM010000020        34808 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.021, whole genome shotgun sequence.
ACCESSION   DADVXM010000020 DADVXM010000000
VERSION     DADVXM010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.021"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(460..2352)
                     /locus_tag="KB927_001082"
     CDS             complement(460..2352)
                     /locus_tag="KB927_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840016.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2349..4076)
                     /locus_tag="KB927_001083"
     CDS             complement(2349..4076)
                     /locus_tag="KB927_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840017.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(4092..4742)
                     /locus_tag="KB927_001084"
     CDS             complement(4092..4742)
                     /locus_tag="KB927_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBB6840018.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4946..5242
                     /locus_tag="KB927_001085"
     CDS             4946..5242
                     /locus_tag="KB927_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6840019.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5434..6054
                     /locus_tag="KB927_001086"
     CDS             5434..6054
                     /locus_tag="KB927_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBB6840020.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(6146..7312)
                     /locus_tag="KB927_001087"
     CDS             complement(6146..7312)
                     /locus_tag="KB927_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6840021.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7324..7677)
                     /locus_tag="KB927_001088"
     CDS             complement(7324..7677)
                     /locus_tag="KB927_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBB6840022.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7805..8827
                     /locus_tag="KB927_001089"
     CDS             7805..8827
                     /locus_tag="KB927_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBB6840023.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8846..9007
                     /locus_tag="KB927_001090"
     CDS             8846..9007
                     /locus_tag="KB927_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840024.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9266..9700)
                     /locus_tag="KB927_001091"
     CDS             complement(9266..9700)
                     /locus_tag="KB927_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840025.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9810..11669)
                     /locus_tag="KB927_001092"
     CDS             complement(9810..11669)
                     /locus_tag="KB927_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6840026.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11787..12946)
                     /locus_tag="KB927_001093"
                     /pseudo
     CDS             complement(11787..12946)
                     /locus_tag="KB927_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(13253..14677)
                     /gene="araA"
                     /locus_tag="KB927_001094"
     CDS             complement(13253..14677)
                     /gene="araA"
                     /locus_tag="KB927_001094"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBB6840027.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14693..15391)
                     /locus_tag="KB927_001095"
     CDS             complement(14693..15391)
                     /locus_tag="KB927_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBB6840028.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15348..17009)
                     /locus_tag="KB927_001096"
     CDS             complement(15348..17009)
                     /locus_tag="KB927_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBB6840029.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17227..18627
                     /locus_tag="KB927_001097"
     CDS             17227..18627
                     /locus_tag="KB927_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBB6840030.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18879..19958)
                     /locus_tag="KB927_001098"
     CDS             complement(18879..19958)
                     /locus_tag="KB927_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6840031.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(20044..21003)
                     /locus_tag="KB927_001099"
     CDS             complement(20044..21003)
                     /locus_tag="KB927_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBB6840032.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(21015..22526)
                     /locus_tag="KB927_001100"
     CDS             complement(21015..22526)
                     /locus_tag="KB927_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBB6840033.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22548..23111)
                     /locus_tag="KB927_001101"
     CDS             complement(22548..23111)
                     /locus_tag="KB927_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBB6840034.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(23117..23980)
                     /locus_tag="KB927_001102"
     CDS             complement(23117..23980)
                     /locus_tag="KB927_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6840035.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23994..24890)
                     /locus_tag="KB927_001103"
     CDS             complement(23994..24890)
                     /locus_tag="KB927_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6840036.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(25065..26354)
                     /locus_tag="KB927_001104"
     CDS             complement(25065..26354)
                     /locus_tag="KB927_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6840037.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26326..27843)
                     /locus_tag="KB927_001105"
     CDS             complement(26326..27843)
                     /locus_tag="KB927_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBB6840038.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            28041..28931
                     /locus_tag="KB927_001106"
     CDS             28041..28931
                     /locus_tag="KB927_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBB6840039.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(29004..29828)
                     /gene="nadE"
                     /locus_tag="KB927_001107"
     CDS             complement(29004..29828)
                     /gene="nadE"
                     /locus_tag="KB927_001107"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBB6840040.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29840..31312)
                     /locus_tag="KB927_001108"
     CDS             complement(29840..31312)
                     /locus_tag="KB927_001108"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBB6840041.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31949..32311)
                     /locus_tag="KB927_001109"
     CDS             complement(31949..32311)
                     /locus_tag="KB927_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBB6840042.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32534..33286
                     /locus_tag="KB927_001110"
     CDS             32534..33286
                     /locus_tag="KB927_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6840043.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33426..34349)
                     /locus_tag="KB927_001111"
     CDS             complement(33426..34349)
                     /locus_tag="KB927_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6840044.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34364..34636)
                     /locus_tag="KB927_001112"
     CDS             complement(34364..34636)
                     /locus_tag="KB927_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840045.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10276 a         7233 c         6011 g        11288 t
ORIGIN      
        1 tgcaagcttt tgaacaccgt ttaaggaaga ggttgtgaaa aagtcgctta gtttcgagta
       61 gtaagaaaaa ttttgtgaaa atggctttct acatttttgc ataaatttgg cttaataccg
      121 agaaactggc ttttgaacac cgtttaccaa gaggttgtga gcctgccgtt taactccgag
      181 tcacaaggag caatttcaaa aaacagcttc tcaggtttgt tgactattgt gacttgtgac
      241 cgaggagttg gcaggagaac accgtttaag gaagaggttg taaaatcagc ggtttgacct
      301 gagtattaga gatacaaaac ggaaaaatag cttctcatat tttgccgttt tttgagctaa
      361 taccgaagga cagctgattg aacaccgttt attcggaaaa agggactgtg acacgacttt
      421 tgtcacagcc cctaaaaaaa ataataaatt tgtactattc tatgaagctt cttcttcaga
      481 aaactgactg ttataaagat ctgcatagaa tccgtctttt tccatcaatg tatcgtggtt
      541 tcctgtttct acgatcgaac catgattcat cacaataatg ttgtctgcat cgcgtattgt
      601 agacaagcgg tgagcaacaa cgaaacttgt ccggttttcc aataggcggt tcatcgcttt
      661 ttgaatcagt atttctgttc gtgtatctac actagatgtt gcttcatcaa ggatcaggac
      721 atctggattt gctaagaatg cccgcgcaat tgtgattagc tgacgctgcc cttgcgaaat
      781 attgcttgca tcctcgttta atacagtgtt atatccttct ggcaatttac gaacaaaatc
      841 gtctacgtga gcagctttag cagcctcaat gatttgttcg tctgttgcat cgtcgttccc
      901 atatttgata ttgtcataga tacttcctgt aaacagccaa gtatcttgca gtaccattga
      961 aaactgtgcg cgcaattcat cacgtgaaag atcacgggta tctacaccat cgtaacgaat
     1021 actacctcca gaaacatcgt agaaccgttc aagaaggttg atcagtgtcg tcttccctgc
     1081 accagtcgga cctacaatag cgaccatctc accaggtttg acatccaagt taaaatcagt
     1141 cattagcaag ttatctggtg tgtagccgaa ttgaacattt tcaaaacgaa ctttgtatgg
     1201 tgtatctttt tcttctggaa ggccagattt ttcattggac atctcttctt catccaacac
     1261 ttcaaatacc cgttcggctg aagcaactgt tgattggata gtgttcatca aacttgcaag
     1321 ttgagtgatt ggttgagaga actgtgttgt atattgcaag aacgcttgaa catcccctaa
     1381 tgtcatgttc ccatttgcaa cttttactcc gcctagtaca gcgacgaaca catagcctag
     1441 atttttaacg aaattcatca acggcatgat gattgccgaa ataaattgag ctttccaacc
     1501 agcggcatac agattctgat tttctttttc aaatacttcc tggtcttttt cagtatgatt
     1561 gaatgtttta acaatggtat gaccaccata tgtttcttct acttggttat tcaataaacc
     1621 taaacttttt tgctgatctg cgaaaaacac ttgtgatttc ggcgctacga tcatcacgat
     1681 gatcaagctt aaagggatca tcaataacgc gactaacgtc aattgccagc tgattgaaag
     1741 catcatcacg atgaccccaa tcaatgtgac tgcactagtt acaaattgag tcaaattttg
     1801 ctgcagcgtg cttgcgatgt tatccatatc attgattgct cgagacatga tatccccatt
     1861 tgtatgtgta tcataatagg aaatcggtac acgattcatt ttggcttcca aatcatgacg
     1921 taattcataa actgttcgtt gggaaacacg tgtcataata aattgctgta aaaagttgaa
     1981 tacagcagaa atcaaataca tcacgattac tgtcgcaatg atctgcgcga ttttatcaaa
     2041 gtctatcgga aattttgtta cttgttggcc ttgttgcatc tgttgagcgc cagccattac
     2101 acctttgaat atttctgtgg ttgctttccc caagaccttt ggtgtttgga tttggaagat
     2161 cacggctgct attgctagta caaatacagc gatgatcgca accatacgtt tagacatata
     2221 gccaaacaat cggcgtaccg ttccccagaa atttttaggc ttttcacctt ttacaccgag
     2281 atttctgcca ggtccaccat gtcctggacc gcctgctggt ccatgagagg gacgtgtgtt
     2341 tgttttactc atgctaagtc ctcctctctt agttgtgaat gaacgatttc ttgataagtt
     2401 tcgtttgttg ctaatagttc ttcatgtgtt cctttgccaa ccagttttcc ttcatctagc
     2461 acaaggatca tatctgcatc cattactgta cttactcgtt gagcaactaa aacggtgata
     2521 ctttctttca tattcgtttt caatgcttgg cgaagattgg catccgtttt gaaatccaac
     2581 gctgagaagg aatcatcaaa cacatagata tctgctgttt tgactaatgc ccgtgcaatt
     2641 gccagacgct gtctttgtcc accagagaag tttcctcctc cttgttccac atggctatct
     2701 aagccatctt ccatctctga aacaaaatct ttagcttgtg cgatttctaa tgctttccaa
     2761 atcatttcat ctgttgcatc cggcttacca tactgcatat tgtctcggat cgttccagag
     2821 aacagaactg ctttttgagg aacaaagccc attaattctc gcaaattata ttgagtcatg
     2881 tcactaatgt ccgttccatt tatttggatc gaaccagatt cgatgtcata taatcgaggg
     2941 atcaaattga ctaaggtcgt tttacctgaa ccagtccccc ctatgattgc gacgatctcg
     3001 cccgacttgg cttggaaatc aatatcttcc aatgcaagtt tttctgctcc atgatatcga
     3061 taattgacat gattgaaggc caatgttgcg ttttttccag caaaagaaac tgttttagga
     3121 ttttcagggt catggatacc gattttttca tccaacactt cattaatacg gtcagctgaa
     3181 gcttgtgcac gaggcaccat gataaaaata gcggaaagca tcataaagct gatcaagatc
     3241 tgcatcgcat aagtcataaa tgcaatcaga ttaccgactt ccaaagtcat atctgctatg
     3301 tagtgtccac caaaccaagt gattgctacg tttgtaccgc tcatgatcaa tgtcatcatt
     3361 ggcatcatca atgcgacgat cgtattaact ttgattgccg tatttgtata atctttattc
     3421 gctaaatcaa aacgattttc ttcaaagcgt gtcttatcga atgctcgaat cactctgacc
     3481 cctgtcaatc cttctcgaaa taccaggttt aaacggtcag ttttcttttg catacttttg
     3541 aataatggaa cagcaaagta catgattccg ccgatcaaaa taatcattac tgggatgaca
     3601 actaagaaga tttttgtcaa ctgatgatct ttttgataag caagtatgct cgcgccaatc
     3661 aacgtgattg gtgcattgat catcatacgt aaaaacattt gtgtaaccat ttggatttga
     3721 gtcacatcat tggtcgttct tgtgatcaaa gaggccgttc catatttatc aaacgcatct
     3781 tttgtcagac tctctgattt tttatagaca tccgtacgca attgcttacc cagtttctgt
     3841 gattcacgag tagcaaaaaa tgtatttgcg atagcagcta agatactgat caaagaaaag
     3901 ccgatcatca caaaacctgt atgccaaata taatcgacat ctccttgcgc taccccttta
     3961 tcaataatat tggaggtaag tgtcggcaaa tataaatctg ccagtacttg gatcaccatg
     4021 aaaactgcag ctgcaattgc tgaagtcaag gagatccgtt ttacgatttt tagcatctag
     4081 ttcccttctt tctatttata tactccgttt ttcagccaag aaagtttcaa attgaattca
     4141 ctgattgctt gctctactga gtaatcttca gatgttgaaa ataagcgata cgaatgcgca
     4201 attgttgtaa atacagtatt catcactaat tggatcagta attccaattc atgatcattt
     4261 tttactttca gcttcgtccg atcgatcaat tcaagcaact cttttgcatc ttgtttgtgt
     4321 tctttatgtg gatcgtgagg cgttttttgg cgactcgtat gaggagcgac ttttcttgag
     4381 gcacggtaat ccatgttcat aaacaagtta cgataaaaag aagcattctc gccttccaaa
     4441 atctcataaa tcattttaga aaaataggat tcgaatcctt tgaatagatc accatcggat
     4501 tctttcatta gttgtaacat atctttagag ctgtcacgtc tcattgtctc aaagtaataa
     4561 aaataaagat cctctttatc ttcaaaatac tgatagaaac tgcctctagg gatatccgct
     4621 aatttgacga tattagcaat cgaagcttct tttaagggta ctctagaaaa ctcgattctc
     4681 gcagcctcga ttagtctttt ttgtttttct ttaggcaaat ggaaaaatgt ctgtgtcggc
     4741 atatggattc tcctttcttt caagatgaca cattgtcata tgacgctatg tcattataac
     4801 acctcctacc tgttttgcaa gacatttgca tagttttttt cattatcatc cgatacatta
     4861 aaaaagtgat aagaggaatc cttccatttg aattaatgag agttgcccat taaaatagcc
     4921 acatactaaa caaaggatga gataaatggc ccaatcaatt agtgtccaag acttcaataa
     4981 attgcctctc gatgctgaca gcatcgtttt agatacaaga aataccttag attacacaaa
     5041 aaaccactta agccactcgc tttctatccc cgctgctatc ttgccaagac aattaaaaaa
     5101 tctagatcca aagaaacttt attatattct aagctataca ggcaggcgat cagaagcatt
     5161 agccgatcaa cttactgcta atggttttcg tgctgtttat atcattggtg ggatggaagc
     5221 tcttcagtcg agtgttgctt gaatattgct tgttagattc aaaagaggct gtgacaaaaa
     5281 atcgtgtcac agcctctttt ataccctgtc tttttttagt tatttattct tcaaccttat
     5341 caatatgact tgatagcctt ttctttttcg agtaaactga ttttgttagt catagttata
     5401 acaatcatag caataaaagg agaaggtaag catatggcat ctgttttagt agtcaaaggt
     5461 catcccctaa ctgcagaaga atcgcgcaca gttaaggcat tgacgtcttt tttaacaagt
     5521 tataaagaaa atcatccaga tgatgaagtg actgttttgg aactttatcg cgatgatatt
     5581 ccggaaatcg atgaagaatt attatcaggt tgggaagcat tacgtgctgg tgcagaattc
     5641 acttccttat cagaaagtca acaacaaaaa attgctcgtt tcaatgaatt gactgatcag
     5701 ttccttgctg ctgataaaat cgttatcgca aacgccttat ggaatctaaa tatcccaaca
     5761 aaattaaaag cttggttcga taccgtcaat gtagctggaa aaacgttccg ctatacagaa
     5821 aacgggccag aaggattagt gacaggtaaa aaagcactgc acatccaatc taatggcggt
     5881 gtatacaacg gacaagactt tgcctctcaa tatgtaaaag gtattttaaa ctttgtaggc
     5941 atcgatcaag tagatcagct attcatcgaa ggaatcgatt atgaccctga ccgtgcagat
     6001 gagttgatgc aaaatgcatt agataaagct gctgctttag gtaaatcatt ttaaaaattg
     6061 agataaatgc atacaaaaga gacagaggaa aaaatcttca aagcagcatt tgtgccttgg
     6121 atattttccc atctgtctct ttttgttatt ctttctgctt tttcaacgga ttttcttcat
     6181 aaagagaaga gattgttgtg taccattcaa aaacatgagt aatcactact ttagctgctg
     6241 cataaacagg aatccccaag atcacaccga tgattccgaa caatttccca gaagtcagca
     6301 gaactaataa aatcgttact ggatggattg ctaactgatt ccctagtact aatggagaga
     6361 tcaagcgtcc ttctattgtc tgctctactg caaaaacgat cagtactttg atgatcatga
     6421 atggacctgc tacaatggct aaaaagatag ccggaatcat cgctaaaaat gatcctaagt
     6481 aagggatcag gtttaaaaaa cccgcaataa tccccaacgt gacagcatac tctaaaccaa
     6541 tgaccgcaaa accaatcata aacatgattg ccacagcaaa agccacagtt agttgtcctc
     6601 ttatataaga agaaacttga ctattcattt cactcagcac attcaacgtc ggtttttgca
     6661 tgcgtgtcgg taaaaatttg acaaaataag gtgctaattg tttaccgtct ttcaatagat
     6721 aaaataagat aaacggcatc gtcagcagag ccactaaaat agtcgctacc gcgccgacaa
     6781 aacttccaag actctgaact gtactcttag atatatcttg gatcatatcg cctgccgaat
     6841 tcatgaactt atcacctgct gtttccaact gttcgcgaaa ttggttgaac agcgggtccc
     6901 gcaaaatctc ggttaattta ttatcaatcg tatctacata ttgagggaag ttactgatga
     6961 agctcactgt ttgttcctga atcttaggga tgatcactac gctcccccat gcgattagtg
     7021 caacaaccaa aacaaacagc ccaatgatac tgtaaagcct tggtactttt cgcttttcaa
     7081 agtaatcaac taccggattc atcaagtaat acaagattcc tgctaaaatg ataggcagac
     7141 ctacgattgc taaaaattgc cagattggtg caaacaaata tgaaactttt gtaaataaaa
     7201 agacgatcag caatattaac aatacaacaa gtaaggctgt gactacttga ttatttaaaa
     7261 accagcgcca aaaccacgat accggtctgt tcttcttatt ttttccttcc ataattcctc
     7321 ctgttagtta taaaaaattt ggcttcccaa accaatagca ggcagtctat gcggatgaag
     7381 atagattcca tttgcaattt gtccttcttc tggacaagca tcaaaaatca atgatacgtg
     7441 agctactgtc tttaaattcc cattggccat cggaccgaca taatcgatcg tatatacctg
     7501 atcatcaaaa gcaattgttc cgcctgcttt caaagaaaaa ggttcgtctt ttgatacttc
     7561 ttgaatcacc gaatattttc gtaaggcagc tgttgctgtt ttatcgaaca aaatcagcat
     7621 gggttcttcc ttgtttattg cttctgtccc aatttctgta atctttgcct gaatcattgc
     7681 actctctcct ttaattgctt tcaaaaacag tataacacat tctcattctt tagccgtgtg
     7741 gaataattat gtgatagaat aaaaacgaaa actatttcat tacaattagg aggaatcagc
     7801 tcatatgatc gaaaagataa ttttaggaac ctatacgcgt cgcgaaagta aaggaatcta
     7861 tacgatcgac cttgatacag aaaaagaaga attagccaac ctttcattag ctgttgaaga
     7921 aaatagccct acctatgtag caaaaagtaa agctggcaat ctttacacag ttactagtgt
     7981 ggatggatta ggtggtgccg gtgcgtacga taaggatttt cattttttga atgcggtaac
     8041 agagtctggc gctcctttgt gttatgtagc ggttgatgaa gcacgtcaat tactatacgg
     8101 ggcgaactat cataaaggtg aagtaaatgt ctaccatata ttaggagatg gcgaactgaa
     8161 agcagcagat tcaatattcc atcaagaagc gacaggtcct cataaaaacc aagatcatgc
     8221 gcatgtccac tatacggatc tgactcctga ccaacgatta gtcgtatgtg atcttggtac
     8281 agatcgtgtg tatacttatg atgtgtccga aaacggcaaa ttgaatcttg taactacctt
     8341 cactgcagag ccaggaacag gccctcgcca tcttgtcttt catccaaatg gacaattcgc
     8401 ttatttattt ggtgaattag acagcacagt ccgcgtgctt tcttataata aagaaacagg
     8461 tgcttttgaa gaattacaga aaatatcgac cttgccagaa gaattcgacg gtgaaaatgg
     8521 aggggcagct atccgcattt caaatgatgg caagttcctt tatgcttcta accgaggaca
     8581 taactcgatt gctgtattcg cagtttttga agatggttcc cacattcaaa acaagcaaat
     8641 catctcaaca gaaggggatt ttccccgcga tttcgcacta gatccaagca ataattttgt
     8701 cgtgtgtgcc aatcagaaca ccgataatct gacattatat cgccgtcatc ctgaaacagg
     8761 attactggaa ttactgaaaa aagatgtcta tgtaccagaa tgtgtctgtg tttattttga
     8821 tcgttagtaa gaaaaggaga atgaaatgaa tcagcaagac gtattagaca gactacggga
     8881 agaactaaat attcctttct ttgatgggaa aatcgaagat aaagagtata gcgaagagga
     8941 atatcagaaa ctcaaagccg atttacagaa ctactttgaa caatatgtac agaatgtaga
     9001 aaactaatca gctttccata ctatctgaaa agaacatcag gacaagactt ttccgtctat
     9061 cctgatgttc ttttctacaa ataaaaaacc gccgagatgg ttagactcga cggaaaagga
     9121 gtatttactc gattttgagt aagtacaagg ttgttgttgg ttataggtat gtcattatca
     9181 taaaggattt tgatcactct atcataaagg taatattaca tttatattag ataactctag
     9241 tttttattgt tatcaaagat ttcttttatt ttttcaacaa caaattagtc attttttgga
     9301 tggcagctgt caattggtct gtcgcttggt cttgttttgc ttcagatgta ttgaatagat
     9361 cttcatctac ccctgattca agatcgatac tttggatcat ttcttcacag cctgctacat
     9421 atgaaagata agctttttca aaatttttat gaatgcccat tgcttttgct ggtggacgca
     9481 aagtactgac tttcataagc attgcccgat atttttttgt tccttcttca aataacagga
     9541 tgatctcttc aagagtcgat ttgtccagtt cacttgtttt tccttcatca attgcgtttc
     9601 tgatcacttc atatttcgga tgcattcctt ctccgattgc ttctgtttcc ttgacgattt
     9661 gatcgatgga ctgcacataa tagccaatat tcggtaacat gttcgttttc ctactttctc
     9721 cattgttgtt attatttatt ctacttgttt ttatcctcaa atgacaagta cttgaaaaaa
     9781 tttaatggtt tctatacagc tcgccattct tattcgtgct caaagaaacc atctgctaaa
     9841 ctatattgtt tccctgcgac aatgtcatat tggatcaatt gatattcgtc gtaaatctct
     9901 tgttgcgagc gattgaattg cgcttcttta taccactgtc cgttttgata gtacagttct
     9961 cgttcaaacg ccggaagttc ctgttctaat gataaaagca gctgataaaa gccatttgtt
    10021 gtctgattcg tctgttccat tagattcgct gcaaaataaa acggactggt gattgcatcg
    10081 tgagtcgttt gcttttctaa ttctccttta ctgtcgaaca taagaaattg tgtttcatgc
    10141 aatgtttgtt tgtcattttt tgcttggatc gtatctgaat agatccctgg aagatgatcc
    10201 ccccaaaaaa caactaaagt ccttctagaa agattcttca attcttccgt gaactgcttc
    10261 agtgccgtgc tgctatagga aatatcttgc agataattct ctaagtcaag tgtcccactt
    10321 ccatctgaag tttttgcagg atagtctaga ttatcatact ttccatcgta gggcatatgt
    10381 gtctgcatcg tgactaaatg aatgaactga ggtgtttttt cttccttgag aagtgtcatt
    10441 acttctttgt aagctgactc atcagaaata tatggattat tctctatcgt atccgtatag
    10501 gtcatcgtac gctcgctgat gaactggtca aatcctaatg tctgataaac atcctctctt
    10561 ttatacatcg aagtattgta tggatggatc gctgtcgtct ggtatgattg tgcgtttaac
    10621 gctgaaacga tagaaggaag ctgatccatt tttggtacaa gcatcgtgta aggggtggtg
    10681 agttgcgcat taaataacgc catagaaaaa ccagtcaatg cttcaaattc gatatttgct
    10741 gttccaccgc catagttttg agaaagcata ttgccactat atgtttgatc agctacttca
    10801 taataatctg ccaatggctc accagatact tctacgccgt ttaatcgact aggatctgag
    10861 aaactttcac tcatcacgaa cacgatgttc ggcgactctt cctctacagt tttatttttt
    10921 tcatcggcta gcttctggta tttttcagtg atttctttga tcttttcttt cgaatatcct
    10981 tcaggttcat ccattggttc taccttcaga ttgtacaaaa acccaccgat aaaaccagtg
    11041 ttatagtagt tcattttctg gctgtaaggt atccatagtg ccgttttatt atatgctttt
    11101 cgcaacaaat tatcgggatt gttgaaatta ctgatatacc ctagcagtcc aattgccaca
    11161 agcagtgtcg ttaatcggat caattggaat cgccttcctt ttttcaggct tcgaaacatg
    11221 taccagcaaa acaatcctat cacggttcct gcggcagcta agatcactgt aaacagcata
    11281 gtgccggtca tatctttcag caatccgatt tcagtgatca tcttcaaatc gtctggataa
    11341 atcggttctt gccgataact cattttcata taatttgcaa aacctaatac accgatggct
    11401 acgacatacg taagggaacc taaagggaca gatcctgcta gtgcaatcag aaaaataaga
    11461 ataatcagca agacgagaca ggctaagaag aatttttccg tatgccaaga aaaagcaaat
    11521 ttcaacgcaa ggtctacgga tagatcattt tgacaccact gcaaaaataa attactaaaa
    11581 acaacaagaa aaaagatact gatgattgct gctgttcctt ttaaaatctt tttctgtttg
    11641 gtcgaaagtc tgcttatata tcttttcaaa tgcttgctcc ttcatttcta tcaataaaag
    11701 aatgttgctt ctcttatttt agttgtacga aattcgaaag taaagaacgg aaagaagaat
    11761 taatgaaatc caaatattct ctttctttat ggcctttctg gtttctttaa taagcggacc
    11821 tttcgtactc cagaaatttt ttctagctgt tgtttcactt gattgagctg ttcaaaatca
    11881 gtactgtcta tgtcaatcaa tatgtagaca tgctcattct tatggttacg cgatatatct
    11941 gcgatcgcta gctcgttctc attcagcaga gaaaatatct ctgctaatat attggttttc
    12001 ttttgataaa atatagtgaa tcgaaacggc gcttggaaaa acattcgtgc ggatggataa
    12061 ttgaccgctt ctctaaccgt accgaacaaa agataatctt ttaaggcttc aactgccaaa
    12121 cgtccgctgt ctgccaaagc ttcctgagtc gatcccctag atgaggcaac ataagtatac
    12181 ggtcattttc taagaactct tcttctggaa aatcagtcaa gtatttagcc agatgttgtt
    12241 tttccaatgc ttgcataaca gcatatttat caacaatttc acttcttcct acattgataa
    12301 gtacagcatc ttttttcatt ttttctatat tcgcctgatc gatcaatcct tttgtatctt
    12361 ctgtcaacgg cagcatgact acgatgtaat ccgaggtaga aagaactgtt tctaaatctg
    12421 cttgccgaac ataatccaac tgggcatcgc ggatagaata acccaagaca tccatcccta
    12481 agctatagca acttagcgct acttttgtgc ctatcgctcc aagaccaaga agaccgatgg
    12541 ttttgccttg caattctcgt cccacataag cacttctttt gttttctgcc tgttctaaaa
    12601 tattaggacc tgttagtgtt tgtaccatac gacttgcttc gattatcgga cgggaagata
    12661 agagcaaaca gcacaaaaca agctctttta ctgcattagc atttacacct ggtgtattca
    12721 tgacgatcgt cccgttttca gaagcttttt caacgttgat cgtgttcacc ccaacaccag
    12781 ctcttgaaat tgctagcaaa tctggtgtaa gccattcatc tttcactttc gtactacgaa
    12841 taactattcc ttcggctggc aaatcatcta ttattttgaa atattcccct tgtaactttt
    12901 ctatctcttg ttctggaata gcatcaatca aatgaacgtg atacataaaa ccccctcctt
    12961 actaacaagt atctcgaaat ttctgcaatt agacaactgt ttaccatttg acttcctaga
    13021 agcaaaaaga gcagttagag cagagtaggc tgagtgataa aaataaggct atgacaagtt
    13081 actgccataa gccttatttt cgagagcaaa atattgaggg tgagatatct tgataaatgg
    13141 tgttccgtta gctgacattg ataataagac taaatttcaa aaaagttgaa aagcaaattt
    13201 cgtcaatctc ttcttatttc ttaaaactaa gtggcttttt cacaacctct ttttatctaa
    13261 taaccactgt ttccaactca actaattttg cccacgtttc aatttgatct gttgttagat
    13321 ttagcgagac aacggtatga tgaccgccac ctgcctgaat ccatgaatgg acaccttcat
    13381 ggaaattcgg tttagttttc cataacacac gtgcaacagg taaattaggt gcttcagtcg
    13441 ttggttcaaa ggcttctact tcattgatca gcagtttata atgcgtaccg aaatctgcca
    13501 tcgatacgac taccccttct cctgctttcc catcaaatac aagacgcgcc ggatcttctc
    13561 tatctcccat tgataaagga gaaacaacga ttcttggttt cgtcgcagca agcgtcggat
    13621 ctacttccat catatgggat tccaagattg cttcttggcc actagctagc tcgtaagtat
    13681 aatcttccat gaatcctgta tctttccctc gagccatgat tttcagcaac cgatcaatcg
    13741 ctgcagtttt ccagtcgcct tccccagcaa aaccgtatcc ttctgccatc aaacgttgta
    13801 cagctagtcc aggtagttgt ttcattccat acaggtcttc aaaattagtc gtaaaagcgt
    13861 tatagcctcc ttcttctaag aaacggcgaa taccgatttc ctgctgagct tgtactttta
    13921 catgttcctc ccatgtcttt tcttcataat caccatagtc gaaggtatac aattccttgt
    13981 actcttcaaa taattgatcg acttcttcgt ctgatacgcg atcgattact tgtacaagat
    14041 ctccgatacc aaaataatca acagtccaac caaattgaat ctgtgcttcc actttgtctc
    14101 cttctgtgac acccacgttt ctcatgttgt caccaaaacg agccactttt attccaaaac
    14161 tttcattata ggctactgca acatccatcc aatcagcaat ctctttttgg atctcaggtc
    14221 gtttccagta gccaacgacg attttatttt gtttatttaa tcgagcattg atgaacccat
    14281 attcgcggtc accatgagcg gattgattta aattcatgaa atccatatcg atcgttttcc
    14341 aaggaatgct ttcgttatat tgcgtagcta aatgaagcaa tggtttttgt agaagctttg
    14401 tcccgcggat ccacattttt gctggtgaga aagtatgcat ccaagtgatc acacctgcta
    14461 cttcttctcg ataattgacc tctttcatga tttttgtgat cgtatcagca gtaactgcta
    14521 attcttgaag gcggattgga taaggcaatt ggccattttc attcagttca tcgaccattt
    14581 cttgtgcatg tttctttact tctcgcagtg cttcttcccc atataaatgc tgtgatccta
    14641 caacaaacca aaattctttt tctccaatat tcaacataat tagccactcc ttttatttgt
    14701 tttgtccgta atacgcattt tttccgtgtt ttcgtaaata atgtttatct aaaatccgtt
    14761 gaggcagctc ttctgaaaat gaattgagct gtctggtaaa taaattcatc ttgcatactt
    14821 catctagtac gactgcgttc attaccgcac tttgcgcatc tttcccccaa gtaaatggac
    14881 cgtgtccgtg taaaagtacc cctggaattg ctaagggatc aattttgcgt tctttgaatg
    14941 tttctatgat aacttttcct gtttcatatt cgtacccgct gtcgatttcc tgttgtgtca
    15001 aaaatcgagc acaaggtacc gatccataaa aagtatctgc atgcgtcgtc cccatcgcag
    15061 gaacatccaa tcctgcttgt gcccagatcg tcgcccatgt cgagtgagta tggacgattc
    15121 ctccgatttg aggaaatgaa cgatataaaa cagcatgagt aggcgtatcc gaagagggat
    15181 tgagtttacc ttcaatgata tgattgtcca agtccacaac gaccatgtcg tctgctgtca
    15241 tctcttcata actgactccg ctaggtttga taacgaaata tcgtgtttca ggatcaaaag
    15301 cgctcacatt tccccatgta tatttgacga gtccgtgttt aggcaagtca agatttgctt
    15361 ggtatacttc ttctttcagt tgttccagca ttttctatca ctcctttttc ttgcaattga
    15421 tgaatcgctg ttttttcaat gtcgatcccc tcacggtaac gtctcataaa tatctgatag
    15481 cctgctattt cttctgctga aggtgtgatg gtgattcctt ggtcttgtcc aaacacgtct
    15541 tctgccaaga agttttctaa agacttccca tgtcgatcca tcatataggc tgctaataac
    15601 gcgattcccc acgctccacc ttctccggct gtgtccatca ctgtaactgg tgcctccata
    15661 gcagatgcta gaatccgctg tccaacttct ggtgttttaa aaatcccccc atgccccact
    15721 aaacgatcaa tttggacatt ctcagatttc aatatatcca ttccgattct cattgcacca
    15781 aaagcactgg ctaaatggat ccgcatgaaa ttcgctaaat caaaacggct acctggtgta
    15841 cgtacaaata atggccttcc ttcatttact cctgtaatgt tttcaccgga aaaataacca
    15901 taagaaagta atcccccgca atccgtatcg ccttctagcg ctttgttgaa taataccgtg
    15961 aataatttat ctctgcttat ctccataccc aaagaattgg taaattcttc aaaaatactg
    16021 acccaagcat tgatatccga agagcagtta ttcgtatgaa ccatgcctac tagttctcct
    16081 gaaggtgtag tgaccatgtc gatttccgga tggacatttt ctagttcttt ttctaatacg
    16141 atcatagcga aggcggaagt accagccgaa atgttccctg tccctttggc tacactgttc
    16201 gtagcgacca taccggttcc tgcatcccct tctggcggac aaaccgggat tcctggtctc
    16261 aaatttcccg tagggtcgat cagataagcc cctgattcgc ttaacttgcc agcttcttct
    16321 cctgctacta gaactttagg caaaatgtga tccaagtcaa tcgctacgtg cgctttttcg
    16381 attaactgac caaaaatatt tttcatttct tgatggtagg ttttcgttga aggatcgata
    16441 ggaaacatgc ctgatgcatc tcctacgcct agtactttct caccagtaag ctgccaatgg
    16501 acataacctg caagcgttgt caaaaaatta atttctttca catgttcttc tttattcaaa
    16561 atagattgat acaaatgagc gatactccat ctctgcggaa tattgtattg aaatttttcc
    16621 gttaatattc gttctgcttc ttcagtgatt gtatttcgcc aagtacgaaa tggtactagt
    16681 aactgttcct tgctatcaaa tgctagataa ccgtgcatca ttgcactgaa cccaatcgac
    16741 ccgattgtcg taagattctc gccatagatt tcgaatactt ctgctgccat ttttcggtaa
    16801 ctgacgcgca gtcctttcca aatatcttct aatgaatagg tccagatacc attttctagt
    16861 ttgttttccc actcataact accagcggca ataggagtaa aagatgaatc aatcaataca
    16921 gctttgatcc tagttgatcc aaactcaatc cctaaagatg tacgaccatc tatgacatct
    16981 aacatacttt gcgcatttac ttccttcata atgatttaac tccctccttc tcgtcaaacc
    17041 tgatcaaacc gtctttttag tagcgcttac aatgattatt gtatactttt gtacgtacat
    17101 gtcaagcagt tatttacaag aatacaataa aaaacacttg ttttgtacgt acataagtta
    17161 taaaatgaaa ttgcttacaa aatctgatca accgccttct cgaaattcta gaaggagaga
    17221 atacttatga aaaaagaaaa aaaagtttcc tcatcgttta tttatttttt tggcgcattt
    17281 ggcggcattc tatttggata tgatattggt gttatgaccg gcgccttacc ttttttacag
    17341 catgattggg gtttggcagg taaagcttct ttgataggat ggatcacgtc ttcggtcatg
    17401 ttaggtgcga tccttggcgg ctctttatct ggtcttcttt ctgataagct tggacgacga
    17461 aaaatgattc ttctttctgc acttattttt atggctggtt ctgtcctttc tgcatctgcc
    17521 cctcacaatg gttcttattt tctgattgca gcaaggattc ttctaggttt agctgttggc
    17581 gctgcatctg ccctagttcc tgcttatatg tctgaaatgg ctcctgctag actaagggga
    17641 agattgtcag ggatcaatca agtgatgatt gcttctggca tgctcctttc ctatgttgca
    17701 gattatttgc taaaagggtt gcctgaaacg atggcttggc gcgtgatgtt agggctcgct
    17761 gctgtccccg cgctgatttt atttttcggt gttttagctc taccagagtc accgcgtttt
    17821 cttatgcaat ctggccgctt ggaagaggca aaaagagtat tgaactatat tcggacacca
    17881 aaagaagctg aacaggaatt cgaacaaatc cagctgaatg tcaaacaaga aaagacaacc
    17941 ggaacttctt ggcatacttt gtttttagaa aaatatcgtt ccttagtcat tgccggtatt
    18001 ggtgtagcag tattccagca atttcaagga gctaatgcta ttttttacta tattccgctg
    18061 atcgtagaaa aagcgactgg gcatgcagcg agcgatgcat tgatgtggcc gatcatccaa
    18121 ggaatcattt tagttgctgg ttctttgctc tttttggtta ttgcagacaa gttcaatcgg
    18181 cgaactttat tgaaaatagg cggtagcgtg atgggacttt ctttcatcct accagctgtt
    18241 ttaggaactg tactggatgc tcatacaaat tcgttgttga ttctcttgtt tttatgtatt
    18301 tatgtcgcat tttattcttg cacatgggct ccactgacat gggtaatcgt aggcgaaata
    18361 ttcccactag ctgtccgcgg gcgagcatct ggcctagcct cttcttttaa ttggattggt
    18421 tctttcctag ttggcttgct ttttcctgtg atgactgctt ctatgtctca agaaatcgtt
    18481 ttcggcattt ttgggatcat ctgcttttta ggggttttat ttattcaaga gatcgtacca
    18541 gaaactcgtg ggaaatcttt agaggaaatc gaacaaagtg catctaaaaa aacttatcct
    18601 aaacgtattt ctatccatca ttcttaaaga ggttgtgaca gaagtggtca gcttcaagaa
    18661 ataagaagga accgcttagt ttccagtcac aaggaacaat ttcaaaaaac agcttctcat
    18721 gtttgatgaa tattgtgact tgtgaccagt tggtaggaga acaccgttta gtggagaggt
    18781 ggtgaaagaa acgttcagcc ttgagcgatg acaaaagctc tcacaaacat tgcgacgagt
    18841 aaccgtagga gcaataagag gcggtaaaaa cccgtctctt atttttcgtt ttctttcact
    18901 gtttcccgtt caactagtac aggttcatag agaatatttg gctgtgcctg tcctttttca
    18961 atcgttgtga cgatccaccg tgcggcatct tgtcccaact tttcttttgg atgcgtcaat
    19021 gttgtcaatt ttttattccc taaatggctt aaagaagaat cgtctgttcc tacgatcgat
    19081 aggtcatctg gaatatgata gccattttct gtcaacttat ctagcattaa actagctatt
    19141 tgatcgttat agcaaatgat gccatctaaa gcttgttctt ctttcaaccg ttgtactgtt
    19201 ttttcagcga ttgtttctcg tgtttccgtg gtgaaagtaa tgatatcttc cgtcaaaaaa
    19261 cgcacattat actgttcaca cgcgctgata aaacctttca tcctgtattt tccttgaaga
    19321 tcgtcgattt ttgtgatgaa caacagacgc tgatgtcctt tttttatcaa atattctgct
    19381 gccataaaac cgactttcac atcatctaaa caaatataag aggcatttaa ctcttcataa
    19441 gcagcattga tcatcaccat cggaatgcct tgttctctca aagcaacata aagtgctaag
    19501 tttgggttat actgattact tttcgtaggc tcaacgatca aaccatctac cccataagca
    19561 atcattttct tcaaacactc tttctccaat tcgtgatcgt tattcgtact ggctaaaagc
    19621 aatgaatacc cagattctcg taattcattt tcgattcctc ggataatcga cggaaaaata
    19681 taatcagaga gatatgtggt gatgacaccg atcgtttttg ttctgttcaa tggtgttttt
    19741 tctttcttat agctgtcatc tacatatgtg cccgaccctt tttctttacg cagatagccc
    19801 tcatttacca acacagcgat tgcttgccga atcgtatgtc tgctgacgtc atatatttct
    19861 tgcagcttga attctgaggg aatggttgta tttacttcgt attcctcacg aaggatcttt
    19921 tgttttatct cttctgcaat atcttgatat tttgccattt gccttgcccc tttttatttg
    19981 tacgtacata tatcataacg agtctgcaag gtttattcaa gcaaaaatca aggtttcttg
    20041 tgctcataag gcatacggaa caggttcacc aaattctgga aatccttgct cattccacgt
    20101 aaagcattgc gcgttcgcgt gccgattagg attgtctaac ggatcccctt tttggttctt
    20161 ctctggtcga gcatgataga tcaaaatatc aaagcacccg tcttctgaaa ccgtaaacga
    20221 gttgtgacca ggaccaaatt gcttattttt ttcagaagaa acgaatactg gctccgataa
    20281 tttatgccat gattctttta ataaaagatt cttgtgctca tcagcccaca gcaggcccat
    20341 ggcatagttt tcatctgttg cactaccaga atacgtaatg aatattttcc cattgcgagt
    20401 aaggactgct ggaccttcat ttactgaaaa accccgtttt tcccattcat actcaggtat
    20461 agaaaggagg atctgcttcc cctttaacgt ccaaggatta tccatttcgg atagataaag
    20521 attagaattc ccagtaattt caggatcttg ttgggcccac acataatata gctttccttg
    20581 agaagagaaa gttgttccgt ctaaactgaa agtttccctt ttcgttttta tttgtccctt
    20641 ttctatccaa tctgtattca ttggatctat atgctgattt tcaagtacga acatgcggtg
    20701 atgatgagat tcatcacgta tagttttatg attgcttgca gcaaagtaaa tataccattt
    20761 tccattgata taatggactt caggtgccca gatcaattca ctcatcggtc cttcttcatg
    20821 agcctgccat acaatcaggc ttgcagcatg ttctaattca ttcagtgact ttgcccttct
    20881 taattcaatc acttggtagc ctggaaccga tcctgtaaaa taataataac catctgtatg
    20941 tttatatacc caaggatctg cccgttgccg aacgatagga ttattataaa gtgtcttcat
    21001 cataacaaat ttcctcacat tttctttatt ctaattacat tccaagagta tttttctatc
    21061 cctacattta attcgtcatg tttttctatt gaaaaatagt ttatttcagg ttttattttt
    21121 tctggttctt cacgtgtatt tttgtccaac agatcgctac tggttaatgt gtagtgctct
    21181 ccttgatcta gcaaattgaa atcatgttca atcgttatct tttgttgttc atttgtgcga
    21241 ttgatcaaga aaatagtcag ctgattgccg ttatctacga tcacactgtc cacataagga
    21301 acatttttta tcttttcaca atcataaaca gggcaaatga tttgttgttt caatacttga
    21361 cctttagcat atttcgataa gtgttgcatc acataataag ttggattcct ccatgcttgt
    21421 cctttagcat ctgtcagtat taaaggtatt gtgtttacta acaatgattg acaactaatc
    21481 tttacgcgat ctgcgtgtcg taaaatagcc agccctaatg aaccaaataa taatgtatct
    21541 tccatagtaa agtaacacca atcgatggga ctaccgactt caaaatccct atgtcttttt
    21601 tccggttggg catgtacatt ccattcatca aacgctagat acattgtttt ctcacttctc
    21661 aaatatcctt ttacataatc acaagtagca acgatttctt caatttgacg atcgaatcga
    21721 taagcttttg caaggtatgt cgctgtatca tcacgctcat ttttaggagg tttagtcaag
    21781 tcttcttcat catacttatc aatatagtta tgcaaagcta aataatctac attctcataa
    21841 gcttcttcta atgcgatacg atcccattca gggtacgatg gtaaacgtgg cgtagagctt
    21901 ccaactaaga ttgtttcaat tgaatcatcc actaacttca tgacttttga ggcttcattt
    21961 gctaacctac catattcata agcactctta gcccccactt gccatggacc gtctagctca
    22021 ttccctaaac accataattt aacgccaaaa ggcttttttt gcccattttt tattcttaaa
    22081 tcactccaga aggttccttt tggaaaatta caatattcta ctaaattttt tgcttcatca
    22141 attccttttg ttcctaaatt caccgtgaat atcggtttcg cttgtacatg actgatccat
    22201 ttaaaaaatt cgtggagtcc aaaagaattt ggttctatac ctcgccatgc taaatcaatt
    22261 ttttttggtc gttgttcttt cctacctaca gtatccaccc aatcataacc agatgtaaag
    22321 tttcctccag gatagcgaat gacacctaat tctaattcct ttacataaga gaggacatct
    22381 tgtctaaacc cgtcaccatc agctgtttca tggcccggtt cataaatccc tgtatagacg
    22441 acacttccca tatgctcaac aaatgagcca aacagccgag aactgatctc tcctaccgta
    22501 aaatcctctc tgatttttac tttcacttct tcgtccaaca gctttcccta cctttcattt
    22561 cctatagtca agataataga tacaagtttc catacgccac cagcaaagat aaaaataaaa
    22621 ggagggaaaa gaaatatgag cagtacaaat cctaataaca atacgcaaca aagaatattt
    22681 ctcaaaaaat caaaaaatac tttccatgca ctttgttcaa aaatttgtaa aaatgtgata
    22741 tctttgtttt cagaaatcac atatatccag gataaaagaa acatggaata aataagtaaa
    22801 actacatatc cactaattga aagtacgatt gtctgttctt ctaataattg attaacaaga
    22861 aaataaataa tgatcgttaa cagactaagg aacaagttct taccaaaatg ttgctttatt
    22921 ccttgaaaga aaaaataaat gatatttcct gatccctcac ctttccattg cgccattaca
    22981 taaaaaacag cacatgtagc aggcacgata gtaataacag gcaaacacac gattacccag
    23041 agaataccta ataagatgta atcagaaacc acaatcaact gtccataaag tttagtctca
    23101 actattttca tcttcctcac tctttcattc cagacatagc tgttccttga acaaaatatt
    23161 tctgtgcaaa aatataaacc actagtaatg gcagcattga aataaccgtt ccagccatta
    23221 caggtccata aaaagaaatg ttctgccctg taaataaagc taaccctgct ggtaaagttc
    23281 tcatttttga actacttgtc aatatcaatg gataaagcaa gtcattccaa ctattcatca
    23341 gcgtgaaaat ccctaatgat aaaagagtag gtttgctcaa tggcaacatg attttcaaaa
    23401 aaatattaaa ctcacttaat ccatcaatgc gtgctgcctc ttccaaagaa tctggtaaag
    23461 taataaaaaa ggaacgcatc atgaagatac caaatgcagt tgtcatacga ggaatgatca
    23521 aacctgcata agtatcaagc atgccaagca aattgacttc aataaataga ggaatcatga
    23581 agacttggaa tgggatcatc attgtcagca aaacgaaata gaacaaaact gattttcctt
    23641 tgaaacgcat acgagcaaat gcataccccg caagagaatc aaagaataca gaagtgatca
    23701 ctgtccctcc agcaaaaatc actgtatttt tgatgtaatc taataaaggg atcgttgtcc
    23761 aaaccttaat atagttatct agggtatagc tatctgcaaa tattctaggc ggaaatgaga
    23821 taatgtcttt ttcgtgttta aaagaagaaa taatcagcca caaaaaagga aacgcaataa
    23881 ccaacaatat aactagcata ctaatcgttc gaatgatttt tttaccacta actgcttttc
    23941 gactattcac agtaactgta atcgagcttt ctggtgccat acaggtttcc ctcctatttc
    24001 atttgttttt ctttccgtga catgtacaca ttagtggaga tagctatagt tgcaacaatg
    24061 ataaacaaaa ccgaagacag tgctgatgca tagcccaatt cataaggtgc tgtaaatcct
    24121 cgactgtaaa tatattgaac agctgtttct gtcttaaatt gtgggccacc agcggttgca
    24181 acatatactt ggtcaaacac ttgcatcgaa ccaatcagat tcgttaaaat acaaaaacct
    24241 aaggagggaa cgatctgagg tagcgtaatg ttaaaaaact gctgtcgatt tgttgcacca
    24301 tccatttgag cagattcata caaagaggga gagattccct gaatagcagt caagagaatc
    24361 gtcatagtaa caccaaaatt cttccaaaca gtcatgatgg ctaccgtcgg catagcaagg
    24421 gttggatcgc gaaaaaattg agggatcggc aagccgactt gtgaaaacaa gtaaggaatc
    24481 gcccctacat tcggatcaag caacatagaa aaaataatcg caattgacgt caatgaacaa
    24541 ataactggaa tgtaaaatgt cgaacgacaa aaacgattga atctggtatt tttagataat
    24601 gctactgctg ctaataaacc aacgataatt tgtgttggcg tttcgagtac ggtgaaatat
    24661 aaagaatgaa tcaacgaatt aactgctcgt tcatcactaa atatacgtgt gaaattttca
    24721 aaacttacaa aatttcttga tgtaaagaaa atattcaaat ctgtaaaact aatagcaaat
    24781 gttcctaaaa gcggtatgac agtaaataat aataaaacta aaaaagatgg agttaaaaac
    24841 aaatacgcag cacgatcagg acgattccaa tatttggtga atccgttcat atagtccacc
    24901 tcatctttca ttttgataaa atatacaatc ttggtttaaa cgaatctgaa taagatatcc
    24961 gaacaatcgc tgtgattttt gcaataacac ctatctgcaa atactaggtc gatcattcag
    25021 atatctgtat cttgccaaca gtctatcctg tataaagttc tgtactattt ttgcagtaat
    25081 tgattgatgg catcatctgc atcgttcatg agtgtctcag gatcttctcc tgctaataat
    25141 ttttcaatca gtggattgat gatatcgtta ttgatcgcag agatttgggt aaaacctggt
    25201 aaatatggct ctgcatagtc catttgtttc gataattcag atacaatagg atcatttttt
    25261 acttcttcat cttttgctac tgaatccaag taggcaggaa aaccattttc gatactccat
    25321 tttttaccaa tttcagttgt attccaatat ttcaaaaact catagacagc ttctttttta
    25381 ttattatctg tacttgccgg aatggcatat cctacgccat ctaaaatagc tgtttttttg
    25441 tctgaatcac tcccttgtgg taaggtagtc acattataat caatctcgtt tgctttcaat
    25501 ccgttattta accatggccc attgatttca atggctagtt gaccagcatt cattaaattg
    25561 tccatttcgg cgccagaaat cgattctgga ccagtcttgt ctacatggat cattttttgg
    25621 atcgctttta acgttttaag gttctcagga gacgcaaatt cagacttagt ataatcatcg
    25681 ttcactaatt taccgccatt tgctaacatc cagttatata acggtgcagt tccatcctta
    25741 ttgaagacaa aacctgatac atttttacta ctatcagtta attttggtgc catttctgtc
    25801 aattcttccc aagtagtagg tggttgttca gtatctaatc cagcttgttt aaacaaatca
    25861 ttattccaat acatatacat gccttgtacc tgcatgggga caaaatactg tttaccttct
    25921 acttcaccta attcaatagc cgtttcttta aaatcagatt tatctactcc atcatattcc
    25981 cagaaatcgt ctaatggttg taccgctccg ttttctacat actgtgcaaa atctggataa
    26041 tttaatgcaa taaagtcagg tgctttttta gaagaaatcg ctgtaggaag tttttcattc
    26101 aaattggccc aagtcatgat atccatttca attttgatgt ttttatcatt tgttttatta
    26161 aattcattaa cgatttcttg caatatttca ccatcagatg cagtaaaccc attccaaaaa
    26221 gtcaaagtca cttctttatc agaatcagat tctgctgaac ttccgccacc gcaagctcct
    26281 aaaatacctg ttgcagctac caacaaagag ccaattaacc attttttacc tttcattttt
    26341 tgttcctcct tcatctgata aacgacatct gaccacattc caagatagcg gtttcaataa
    26401 acaattgatt ttcccatctt cagcttttac atttgttgaa tgacttggtt ttacttgttc
    26461 acttttagga agattagttg cttttgtatc aaatccactc atttcagaaa aatcaatcac
    26521 tccctctaat gataattcag acaagtgaac agttagattc atttcttctt ctccacggtt
    26581 aactgcaaat atgacaagtt ctttgtcatt tattacggct atactttcta aatacggcac
    26641 ttcttcaaaa tcttccgtcg catagtttgc tgaacgaatt tgtgggctta acacctctcc
    26701 ttgtccatac acagcagctt gcataaatgg ataatagatc gtctgtctcc aagcttctcc
    26761 gtttgtttct gtcctgattg gtgcaataac atttaccaat tgagcaagac aagcaatctt
    26821 tactctatct gcatgtttca ataaagtgat taatagacag cctaatagta atgcatcttc
    26881 aaaattatag ttatcttcta gtaaaggagg agcaatctgc caaggcgctg cttgctcatc
    26941 ttgttccgct gaatgatacc aaatattcca ttcatcaaag gacaggttga tctgcttctt
    27001 actatgtttc ttcgccttga ctgtatcgca catcgctgtc acttcagaaa tgaaccgatc
    27061 catgtctaag gaacgtgcaa gataatgaga aagatcattt ttttggttgc cataatattg
    27121 atgcagagac aaataatcta tttgatcgta cgcttgatca agaactgtta actcccaatc
    27181 accaaatgta ggcatttgcc gattcgaact tccgcataaa accacctcaa ttgaatcatc
    27241 tacgagtttc atcgccttag ccgtttcctc tgctaaccgt ccatattctt ccgctgtttt
    27301 atgtccaatc tgccaaggac cgtccatttc attccctaaa caccatgtct taattccaaa
    27361 agggctctct tgaccattcg aacgccttaa atcactccaa taagttcctt taggaaaatt
    27421 acaatattcg actaaattac gagctgcatc tactccacga gtacccagat tgacagccat
    27481 attgatttcg gcccccacat gctgacacca gttataaaat tcatgaatcc caacttcatt
    27541 cgtttcaatt gtccgccaag ctaaatccaa ccttctaggt ctatttgcta tgggcccaat
    27601 actgtcttcc caacgaaatc ctgacacaaa atttccacca ggatatctaa tcatgggaat
    27661 gttcaattct tttaccaagt gaatgacgtc ttggcgaaat ccacttttat tagctgatgg
    27721 atgatctggc tgataaatcc cttcatatac tgctcgtccc atatgttcaa taaatgaact
    27781 gtacaaccgc ggatcaactt tgcctacacg cttgacacta ctaatcaaca ttgtggcttc
    27841 cataactgac ctcctttaat ttatacatga ataatacacc tcgttgaaag cgttgtcaat
    27901 aatataaatg ttaaacttac ttatttttta tcgattttaa ttaaccaaaa tattaataat
    27961 gattaaaaca aataatttaa tataactttt attaacaaat atgttaatat ataagaaaaa
    28021 ccttttaaga ggtgatatat atgcaactac aaataaacga agaatcctta ccggtatatg
    28081 aagcattagc tagtaaaaca aggatcaaga tcatccagct actttccaaa aaaaagatga
    28141 atgtcaaaga tttggcaaaa gaacttggag tgagcagtgc tatcacgacg atgcacgtga
    28201 aaaagctaga ggaagcaaac atcatcaaaa cagaaaaagt aggacaacaa aaaatttcga
    28261 gccttcgtgt cgataaaatc gatatcagtt ttccagaaaa aatattcaat gcttttgata
    28321 cgaaagaaac atcgatacct attggtcact atacaaatta tgcaattgaa ccaacatgcg
    28381 gtttagctac gatccatgat tttatcggga aagtggatga accacgctat tttatggatc
    28441 ctcgaaggat ggatgcccgc attctctggt ttaccagcgg atttgtcgag tatcaggcac
    28501 ctaatttttt aaatacagag gatacattgg agatgttgga agtttctgtg gaaatttctt
    28561 ctgaatttcc tttttcaaat gacaattggc cttcagatat cactttcagc ctaaatggtg
    28621 tggagctagg aacatggacg agccctggag attttgctga tatccgcggt aaatatacgc
    28681 ctgattggta tccagataat cttaatcaat acggcttgct gaagacgatc cgaattacca
    28741 aacacttgac gaatatgaat ggagaaccct tgtcaaacat cacgatcaac gacatcccta
    28801 aagagcaaga cacttggcat ttgcgaatcg aagtgaaaga cgatgccaaa catgtggggg
    28861 gctgtacttt atttggtaaa ggattcggta attacgatca ggatatcaaa ttaaaagttt
    28921 actacagctg atatttttct tttctatttt ataaaacaaa aacagccaat ccctatgaag
    28981 ggacggctgt ttttgcttta ttgttatttc cagaaatcat ccaaaacgga aattggcaaa
    29041 tgtcgtttat gttgtgtctt gttccaccat gcttcgattt tttcttgtgc ttgagcggga
    29101 acttcttttc cttctagata atcatcaatt tcattatatg tgacacctag tgcgacttca
    29161 tctgcaatca ttggtttccc atcttcaaga tctgcagtcg gaatttttgt gtataatttt
    29221 tccggtgcat tcaatgcttg aagcaattgt ttcccttgtc gtttgtccaa acggaataat
    29281 ggcaaaatgt cggctccacc atcaccaaat ttcgtgaaga atccagtaat gttttctgca
    29341 gcatgatctg tccctaatac ggctcctgct ctttctccag ctacggcata ttgcgtaatc
    29401 atacgttgac gtgctttgat atttcctttg ttaaaatcgc tgattcccac acctgcttcg
    29461 cttaatactt gtacttgtgc atcaacagct ggtttgatat ttactcgcag actaacatcg
    29521 ggctggataa agtcaagagc agcttttgca tcttcttcat ctgcttgttc accataagga
    29581 agacgaacag cgataaattg atagttttca tcttttgttt cttcacgcat ttcttccatc
    29641 gttagttgcg ccaaacggcc tgctaaagta gaatcttggc cgccgctgat acctagtaca
    29701 aaagttttaa gaaacggata ttttttcaaa tatgctttca taaagtcaat acttttacgt
    29761 atttcttctt ttggatcaat tgttggtttg acacctaatt cattgataat ttctgtctgc
    29821 aggctcattt attctcctcc tatgcttctg tatgaagttc tgctacgctt tttttcattc
    29881 gttccatgat agccatttta tggttccagc attcagtaga cagatcgact gggtattttt
    29941 gcggattcaa gtctcgttta tactcttccc atagtgaatc tagattttct tttgtatatt
    30001 ctttgatttc gtttagtgca ggtaattcgt aaactctttt tccttcgata aagatatctt
    30061 gtaaaactgg gcgagctgta aagtctcgaa cagttttatt gataaacgta tgcactggat
    30121 ggaacatgaa gatagcttct tcttctcgag ggtcttcatc ccataatgtc acgtagtctc
    30181 cttcagattt cccatcaaaa tttcgagtga tgcgccacac ttgttttttc cctggagtag
    30241 ttactttttc tgcattgctt gataacttga tcgtatccat catttttcct tcatcatctt
    30301 cgatcgatac tagcttgaat actgcaccaa gggctggctg atcataggct gtgatcaatt
    30361 ttgtcccaac accccataca tcaattttag ctttttgcat ctttaaattc aaaatcgttg
    30421 cttcatccaa gtcattcgaa gcatagattt ttgcttccgt aaatccggct gcatctaatt
    30481 gttcccgaac acgcttagat atataggcca tatctccact gtcgatgcgt acgccttgga
    30541 agttgatttt gtcacctaat tctttcgcca cgcgaatcgc acttggcaca cctgatttca
    30601 acgtatcata agtgtcgact aagaacacgc agtctttatg ggttttagcg taggccataa
    30661 atgcttcata atcatttcca taagattgga ctaacgaatg agcatgggtc ccgctagctg
    30721 gtatcccaaa tatcttccca gcacgtacat tgcttgttgc atctgctccg ccgatatatg
    30781 ccgctctagt tccccagact gctgcatcca gttcttgtgc ccgtctagtt ccaaattcca
    30841 atagtggatc ttctccgatg acagatttga tacgagctgc ttttgtcgcg atcaacgttt
    30901 ggaaattgac catattcaac agtgctgttt ctactaattg gcagtgcgct aaaggccctt
    30961 ccacttggat taatggttca tttgcaaaaa ctagttctcc ttcacgagca gaacgaactg
    31021 ttgctttaaa ttcaaaattt tgtaaatact ccaaaaaacc ttcaggatag acttctaatc
    31081 cacgcaagta agcaatatcg gaatcattga acgtcagatt ctctaaataa ttgactaacc
    31141 gttccaatcc tgcaaaaacc gcgtatccgt ggttaaaagg catttctcga aagtaacatt
    31201 caaaaacagc atgtaaatca gctcgaccta attcccagta tgtctgcatc atattgattt
    31261 gatatagatc cgtatgcagc gtcaaactgt cgtctgggta agtattattc atcttgtatt
    31321 actcctcttg gcaagttttc atttcctacc cattataaca aaaaaaatta ataggaaaag
    31381 aaatcttcca ttttttctga aaaagcacat gttttacgga tatttcttgc taaaaatgaa
    31441 ctccatctgc taaaactatc ctttcttatt ggtatttaac ctaaacgaga aagaatactt
    31501 attttattca atgtatccga gacacgaaga aattagcgtt ttctattttt cttacttgat
    31561 aaaataagta gattttccta ctacaatcgt agccgttaag ataccgatga ttgaacaaat
    31621 ataaccaaat gtctctacaa cataatcaat ggcaaaagtt tttgaagcaa taatacgtct
    31681 ttcctttttt gcttcttatc cccaaagaaa cggatataac ttattatgta ttgaattttt
    31741 ttggaaaggc gaattatgac aagatatacc ttgcgttgaa aaaactcgcg gaaaaaatat
    31801 cacacgtttt taaaaagata caaagtaaga aagcagctgt caatagaatg gaaacaaaaa
    31861 tggcgagaca tcaatcagtc tcgccttgtt ttttattgta tacattagat atggagcagg
    31921 ttaccataaa gatgattatt agtcgttatt aaatagaatc cttcgtattt ttttgttcta
    31981 tcactacaat atctttattt ggacgtttga attgtattcc ggcacgttct agctcctgtt
    32041 tcactcctac atggactttg acatcttctc gtgtcatttt taaaacgtga tgaatcgcat
    32101 agtcgatttc ttgccttgtg atttttttct tcgtattgat catcacgact tgctttttat
    32161 catatgtgtc taccaatagc agttgtgttc gatctaacga aaataatttg taataattaa
    32221 tagccgtatt cccaaaaaag aattccacta ctttaggata aaatgtctta atatttaaat
    32281 tactattcac aggtgtttcg attagcttca tctcattcct cttttctata tagtcgattt
    32341 agatccaatc ttaagttatg ttaccatctt tcctagcatt aaggaatcgg ttacaattga
    32401 acctttaaag acaaaaggat ttacctttta tcacttaata gtataacata atttcgtgag
    32461 aaaaaaatac aattttttct tgaccatctc gttacgtaaa ggattatgct tacatttgtc
    32521 aggaggaaaa ataatggagt acacaataaa gaaaatgtca gagatatcag gagtcagtcc
    32581 gagaaccttg cgcttttatg atgagattgg actgctaaaa ccagctagga tcaattcttc
    32641 aggttatcgg atttatggca aaaaagaagt cgatcgtctg caacacatct tattttatcg
    32701 aacaatggca ttcaagttgg atgatatcca agaggtctta gacaatccat cttttgacca
    32761 ccagaaagct ttaatcaagc atcagcaaat gttgctggaa aaacgggcac aaatcgatac
    32821 cctcttgaca actgtccaac agacacttga tatgtacgaa ggaggaagaa aaatgagtga
    32881 caaagaaaaa tttgaagggt ttaaacaaca aaagttgaaa gaaaatgaag aatcctatgg
    32941 acaagagatt cgacaaaaat acggaaaaaa aaaggttaca gcatccaatg aaaaatggat
    33001 gaatatggat aaagaaacgt atgaagaaat gcaaactgtt gaaaagcaga tgttatttga
    33061 tctcactctt tacttaaaag aaccagaaga tgaaagctta gcagaccgta tcttccaagc
    33121 tcataagaag tggttctctt acagctggcc tgaatatcag ccaaaagcgc ataaaggact
    33181 aggaatgatg tacgaagccg atgaacggtt cactgcatat tatgacgagc gaagtggtca
    33241 tggtgcagca aaagctttaa atgaaattat ccaaaaaaag gcgtaatctt ttacatgatc
    33301 caacaaaaaa gtacacgtaa aatgacctaa taacaaaaca gcagacaccc aagttagatt
    33361 tttatgctaa cttttggtgt ctgctccatt ctttcacaag ttttttcatc ctactttaaa
    33421 tatattcatc gttgaataaa cgtataaggt attttcactt tatccttttt ttctgtaaga
    33481 aacaattgaa atgccatttc tccgcaagct tccagatggt ggtcgatggt tgggaaacca
    33541 agaagctcgc tgatcagcaa attatcgcgt ccaatcacca ctggtgtctt atcttgcaga
    33601 tagctttgca agatgcctgc tgcaaccata tccgaatttg taaagacacc atcaactcca
    33661 agctctttaa aaaagaagcc tgcttgtttt cctttctctg catctataca atcccaaaaa
    33721 acaagtgatt catcaaaaga tggaaaaagt tgatgacata gctgcaaagt gatttttgag
    33781 ttataactta gcctgccact tcgccccaac gtgatgccca attgctttat accttgctgc
    33841 ttcaaataag taagaccttc tgtaattgat tgttctcgat caataaagac acagcttgcc
    33901 tgttttccct tgatttcttc acaaaaaact agaggtccat atttttgata tgccaataaa
    33961 tcatctagtg tattggcacg agacgtaatg atcaatccat cgaaagcttt agctgcaaat
    34021 tcttcaagat accttcgctc tttttcttta tgatagcccg tcggtaaaag tgtcactttg
    34081 taatcataat caaacgctgc ttcaatgatc ccactgatca actgatcaaa atacggatga
    34141 ttggtataag gcagaatcac tccaatgctt ttcgtttttc cataacttaa ctgtctggca
    34201 tttgcattag ggatataatc gacttctttc atgaccgcaa gtatttcttt ccttttttcc
    34261 tcatctacat atggatgtcc attgattaca cgtgaaatag tagaaactga ataacctgtg
    34321 agctttgcga tatctcgaat gtttgccact gctgcttcgc cacctataca aaaagatttt
    34381 cttgtaaata gtctaccaca gctggaccgc attcaaaaaa ctgatacatt tttccttcat
    34441 gcgaaaaact gatccgctgc ccgccccaat atatatcttt tgtcaaattt tcgatttcat
    34501 tcattggtat ttcttttact atattcctat tcaacccttg aaaactgtac aacgttaata
    34561 cggatccctt gaactcgaca aacgcataaa aataattgtt cgttgtgcca tctgttatct
    34621 ctacataagt attcattgca agccctcctt ttgatacttt gagtatagtg tatgaaacgc
    34681 gtctcatagc aaggagtttg ttttgccaaa gaaaagtttt attcctcttt cattattacc
    34741 aaagtctctt attttaaatt gaatacatta taatgatact gtaaatatat ctttattatt
    34801 agtgaatg
//
LOCUS       DADVXM010000021        34643 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.022, whole genome shotgun sequence.
ACCESSION   DADVXM010000021 DADVXM010000000
VERSION     DADVXM010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.022"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            598..1287
                     /locus_tag="KB927_001113"
     CDS             598..1287
                     /locus_tag="KB927_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6840046.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="KB927_001114"
     CDS             1274..2482
                     /locus_tag="KB927_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6840047.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="KB927_001115"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="KB927_001115"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBB6840048.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="KB927_001116"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="KB927_001116"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBB6840049.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="KB927_001117"
     CDS             complement(6585..7280)
                     /locus_tag="KB927_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBB6840050.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="KB927_001118"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="KB927_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBB6840051.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="KB927_001119"
     CDS             complement(8479..8670)
                     /locus_tag="KB927_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBB6840052.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="KB927_001120"
     CDS             complement(8691..9581)
                     /locus_tag="KB927_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBB6840053.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="KB927_001121"
     CDS             complement(9568..10335)
                     /locus_tag="KB927_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6840054.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="KB927_001122"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="KB927_001122"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBB6840055.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="KB927_001123"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="KB927_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBB6840056.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="KB927_001124"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="KB927_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBB6840057.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14906..15289
                     /locus_tag="KB927_001125"
     CDS             14906..15289
                     /locus_tag="KB927_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840058.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15457..16215)
                     /locus_tag="KB927_001126"
     CDS             complement(15457..16215)
                     /locus_tag="KB927_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBB6840059.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="KB927_001127"
     CDS             complement(16233..17051)
                     /locus_tag="KB927_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBB6840060.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="KB927_001128"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="KB927_001128"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBB6840061.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="KB927_001129"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="KB927_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBB6840062.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18179..19513
                     /gene="dnaA"
                     /locus_tag="KB927_001130"
     CDS             18179..19513
                     /gene="dnaA"
                     /locus_tag="KB927_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBB6840063.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19711..20841
                     /gene="dnaN"
                     /locus_tag="KB927_001131"
     CDS             19711..20841
                     /gene="dnaN"
                     /locus_tag="KB927_001131"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBB6840064.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21070..21312
                     /gene="yaaA"
                     /locus_tag="KB927_001132"
     CDS             21070..21312
                     /gene="yaaA"
                     /locus_tag="KB927_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBB6840065.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21299..22423
                     /gene="recF"
                     /locus_tag="KB927_001133"
     CDS             21299..22423
                     /gene="recF"
                     /locus_tag="KB927_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBB6840066.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22420..24366
                     /gene="gyrB"
                     /locus_tag="KB927_001134"
     CDS             22420..24366
                     /gene="gyrB"
                     /locus_tag="KB927_001134"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBB6840067.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24386..26857
                     /gene="gyrA"
                     /locus_tag="KB927_001135"
     CDS             24386..26857
                     /gene="gyrA"
                     /locus_tag="KB927_001135"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBB6840068.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27093..27392
                     /locus_tag="KB927_001136"
     CDS             27093..27392
                     /locus_tag="KB927_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBB6840069.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27442..27954
                     /gene="ssb"
                     /locus_tag="KB927_001137"
     CDS             27442..27954
                     /gene="ssb"
                     /locus_tag="KB927_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBB6840070.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27980..28216
                     /locus_tag="KB927_001138"
     CDS             27980..28216
                     /locus_tag="KB927_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBB6840071.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28359..30332
                     /locus_tag="KB927_001139"
     CDS             28359..30332
                     /locus_tag="KB927_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBB6840072.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30338..30790
                     /gene="rplI"
                     /locus_tag="KB927_001140"
     CDS             30338..30790
                     /gene="rplI"
                     /locus_tag="KB927_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBB6840073.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31064..32431
                     /gene="dnaB"
                     /locus_tag="KB927_001141"
     CDS             31064..32431
                     /gene="dnaB"
                     /locus_tag="KB927_001141"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBB6840074.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33211..34503
                     /locus_tag="KB927_001142"
     CDS             33211..34503
                     /locus_tag="KB927_001142"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBB6840075.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10556 a         6735 c         6844 g        10508 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgtggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtat attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgggca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggaa tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaaagg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg cgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tgtatttttt atccacagac gcaagaggaa atctattggt ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa ctttttttga caactgtgtt tttctctttt ttctttttgt
    18061 cgattgtgtg gataattgta attaaaaaat ttttttcttc ggtttctgtg gaaaactatt
    18121 gaaaaaaatg ctaaattagt actagttatt cactttttaa tgaaggagga ggccttatat
    18181 ggtatccctc gatgctttat ggaatgaatt aaaagcaaca taccaaaagg atttatcgcc
    18241 tgctagctat aatacatgga tcgaaacagc gaaccctcga acccttgatc aaaaccagct
    18301 cgttgttgag gttcctagca agattcataa agaatattgg gaaaaaaacc tggcgacaaa
    18361 aatcgttgaa gtcggttata tgttatcagg aaatgagatt atccctcgct ttattactgg
    18421 cgaagaagca gagcaagaag aagttataga agaaaaaaat ccaaaagttg tggcacctag
    18481 tccgctaaaa aaagccatgc tgaaccctaa atataccttt gatacgtttg tcattggtaa
    18541 aggaaaccag atggctcatg cagcagcgct cgttgtagca gaagatccag gttctattta
    18601 taacccgctc ttcttttatg gaggcgtggg acttggtaag actcacttga tgcatgcaat
    18661 tggtcatcaa atgctgcaaa gtcagcctaa tgccaaagta aaatatgtaa gcagtgaaac
    18721 ttttgctaat gatttcatca attcgatcca aaacaaaaca gcagaagagt tccgtcaaga
    18781 atatcgaaat gttgatttac tgctagtgga tgacattcaa ttttttgcag aaaaagaagc
    18841 tacgcaagaa gagtttttcc atactttcaa tgccttgtac aatgaaggga aacaaatcgt
    18901 actaaccagt gatcggttgc caaacgagat tccgaaactg caagaacgcc ttgtttctcg
    18961 ctttgcatgg gggctgtctg ttgatattac accgccggat cttgaaacaa gaacagcgat
    19021 tttacgtaaa aaagcggcgg ctgaacgtct agagatccca gatgacacac taagctacat
    19081 cgcaggacaa attgattcta acattcgtga attagaaggt gcgcttgttc gagtgcaagc
    19141 ttttgctgcg atgaatagtg aagatatttc gactagtcta gctgcagacg cactgaaaac
    19201 gttaaaatca ggaaaaggac atcctcaatt gtcaatcctg cagatccaag aagaagtggc
    19261 aaagtattat cacatccaat tgaaagatct caaaggaaag aaacgcgtca aatctattgt
    19321 tgttcctaga caaatcgcta tgtatttggc acgtgagctc acagataatt ctttaccgaa
    19381 aatcggagct gaattcggtg gcaaggatca tacaacggtt atccatgctc atgaaaaaat
    19441 ccagcagctg atggattcta gtgtcagtat gcaaaatgaa gtatcagaaa tcaaaaactt
    19501 tttactaaat taatttgtcg attctatcaa ctgaaaatag catgtggata aaagaaaaaa
    19561 acgttcaaaa gttatacaca ctttttccac agctgttttt tcgtttctct cttacgtttt
    19621 ttgagttttc cacagaatca acatgcccta ttacttttat tattcttttt aactaataat
    19681 aaataaacaa acattcaaag gagatacatc atgaaagtta ctttaaaccg agctagcttt
    19741 atgcaggaat tgcaaactgt tcaacgagct atttcaagca aaaccacgat ccctattttg
    19801 acaggtgtaa aaatcacact gacacaagaa ggtttgactt tgacggggag caacgctgat
    19861 atatcaattg aaactttttt gtctgttgaa aacgaaaaag caaatatgca aatcgaatct
    19921 actggttcca ttgttttaca agcacgtttc tttagcgaaa tcattcggag acttcctgaa
    19981 gaaacattta ctttagaagt tttagaaaat aaacaagtag cgatcacttc tggaaaagcg
    20041 aattttatcg taaatggatt agatgcagat aactatcctc atcttcctgt tgtcgaaagc
    20101 cataaccaga tgaaattacc tgtacacgta ttgactaaac taatcaacga aacagttttt
    20161 gctgtctcac aacatgagag tcgtccaatc ttgacaggtg tgcatttcat tttatctgat
    20221 aattctttat tagctgtagc tactgattct caccgtctaa gtcaacgcgt gattccagta
    20281 gaacaagcgg ctgatcattt tgatattgtt attcctggaa aaagtttgat cgaattatct
    20341 cgctcattaa caaatgaaga agaaatcgtc gaaatcagca ttatggaaaa ccaagtgttg
    20401 ttcaaaacag aaacgatgta tttctattcc cgtttgctag aaggaaacta tccagatacc
    20461 aatcgtttga ttccttcaag ttttaataca gaggttgaat tttctgttcc tagcttttta
    20521 gcggcgatcg aacgggcttc tttactttct catgaaggcc gtaacaacat cgttcgttta
    20581 tctattcgtc cagatgcggt tgttttatac ggaaattcgc cagaaatcgg gaaagtagaa
    20641 gaaagcttga gttatacagc aagcagtggc gatccattag atatttcttt caatccggat
    20701 tatatgaaag cagcgttgcg tgcatttgga gatatgagca tcaaagtgaa atttatctct
    20761 gctattcgtc catttacatt ggaaccaacg gaagatggcg ttcaatttat tcagctgatt
    20821 actcctgtac gtacaaatta acaatgattt tcaatgttct tgaaaattta attgaaaaga
    20881 aatagaaaaa ataaaatttt aaacagaagg ccctaaaatc tcttttaagg ctttctgttt
    20941 atttttgttt aaatcacctt ttttagatta aatcgtctta tatggaaaaa tatatggata
    21001 aatttgtttt attgcgaaaa aaaaggtata atagagtata cttttaataa tgaaaatgag
    21061 ggatgggcat tgaaacaaca agtcattcta aatacggaat tcatgacgtt gggccaaatg
    21121 ttgaaagaag tcacagttat cggtagtggc ggacaagcaa aatggtattt ggcagaaaac
    21181 actgtgttag tcgatggcga accagaaaat cgtcgtggac gcaaacttta tcccggcatg
    21241 atggttgaag ttccagaagt aggaactttt tttatggtaa aaaaaggaaa cgacgataat
    21301 gaggctgaat aagctgtatt taaaaaatta tcgaaattac gaagagctga acatcgaatt
    21361 ttccaagaac ctcgtcatct ttttaggaga aaatgcgcaa ggaaaaacga atcttttgga
    21421 aagtatctac gtattagcta tgacgcgaag tcatcggaca agtagtgagc aggaattgat
    21481 tggctggact gacgatcagg cgatgattca aggagagatc acaaaaggtt catccactct
    21541 tccattagaa atcttattat ctaaaaaagg ccgaaaaacc aagatcaacc atatcgaaca
    21601 gaaaaagtta agtacttacg tgggacaaat gaatgtcatt ttatttgcac cagaagatct
    21661 ttctttagta aaaggcagcc cgcagaccag gcggaagttt ttagatatgg aattaggcca
    21721 gatcaatcca atctatcttt atgatcttgt ccaataccaa gcaattttga aacaaagaaa
    21781 ccagtacttg aagcaattga atgaaaaaaa acaaactgat ttgctttatt tggatatttt
    21841 gtccgaacaa ctagcagcgt ttggcagcaa agtattgaaa gcaagagcac agttcgtcaa
    21901 gcgattggag ttttgggcta attctttgca tcagcaaatc acccatcaaa aagagcagct
    21961 ggaaatcgag tatctcaccg cagtcgattc tttagaaaca catacgcaag agcaaatcca
    22021 agaacaattt ctcgcacttt tgaaccaaaa taaaaagaaa gacctttttc ggggaacaac
    22081 gacagttggt cctcatcgtg acgatctttc cttttttatt aatcagaaaa atgtgcagac
    22141 ttatggatcg caaggacagc aaagaacaac tgcactaagt gtcaaattag cagaaatcga
    22201 tttgattaaa gaagagacag gggaatatcc aatccttttg ttagatgatg tgatgagcga
    22261 gctggatgat aatcgtcaac tccatctgct agaaacaatc gaaggaaaag ttcaaacgtt
    22321 cttaacaaca acgacacttg accatgtaaa aaataaaatg actgttgaac ctgagatttt
    22381 ttatgttcaa caagggaaac taaaaggaga agaaactgaa tgacagaaga aagaagttta
    22441 gtagaacgcg ctaaagagta tgatgccagt cagattcaag tacttgaagg acttgaagcc
    22501 gttcgtaaac gacctggcat gtatatcggt tcgactagtt ctgagggtct gcatcacctt
    22561 gtttgggaaa ttgtcgataa ttcgatcgat gaagtattag caggttttgc aacgaaaatc
    22621 catgtgatta ttgaaaaaga caacagtatc accgttattg acgacggtcg ggggatacct
    22681 gtagatatcc aggcaaaaac tggacgtcct gcagttgaaa cggtctttac tgttttacat
    22741 gctggaggaa aattcggcgg tggtgggtac aaagtttctg gtggacttca cggagtagga
    22801 tcttctgttg ttaacgcgct ttctacacag cttgatgtca aagtatacaa agaaggaaat
    22861 gtgtactatc aagaatatcg tcgtggagct gtagtggacg acttaaagat tatcgaacaa
    22921 acggatcgcc atggaacaac ggttcacttt acgccagacc ctgaaatttt tacagagaca
    22981 actgagtttg atttttcaaa attggctacc cggatccgtg aacttgcttt cttgaaccgc
    23041 gggatgcgta tatcgattga agacaaacga gaagaagaac cagtcatcaa tgaataccat
    23101 tatgacggcg ggattaaaag ttatgtcgaa tacttgaatg caaacaaaac cgtgattttt
    23161 ccagaacctg tatatttgga aggtgaacag caagatatcg cagttgaagt ctctatgcaa
    23221 tatacagacg gctaccattc caatatcatg agttttgcca acaatatcca tacgtatgaa
    23281 ggcggaacac atgaatcagg attcaagact gctttaactc gtgtgataaa tgattatgcc
    23341 cgaaaacaaa agctgatgaa agaaaatgac gacaacttga ccggtgaaga cgtgcgagaa
    23401 ggattgacag ctgttatttc tatcaagcat cctgaccctc aattcgaagg acaaacaaaa
    23461 acaaaattgg gcaattccga agtacggaca gtcactgatc ggttatttag cgaacatttc
    23521 atgaaattct tgctggaaaa cccaagtgtg ggccgtcaaa ttgttgaaaa aggattacta
    23581 gcttccagag ctcgtctagc agcgaaacgt gcgcgtgaag taacgagacg taaaggtgct
    23641 ttagagatta gtaatctgcc aggaaaatta gcggactgct ctagcaacga tcctgaaaaa
    23701 tgcgaattgt tcatcgtcga aggagattcg gccggcggat cagctaagca aggtcgtaat
    23761 cgagagtttc aagccatctt gcctattcgt gggaaaatct tgaatgttga aaaagcaagc
    23821 atggacaaga tcttggcaaa tgaagagatc cggtctttat ttactgctat gggtacaggg
    23881 tttggagaag attttgatgt atcgaaagct cgctaccaca aattagttat catgactgat
    23941 gccgatgtcg acggcgcgca tatccgtaca ttgctgctga ctctttttta tcgttacatg
    24001 cgtcctattg ttgaagctgg atacgtctat attgctcagc cacctttata cggggtaaaa
    24061 caagggaaga atattacgta tgtacaacca ggaaaaaatg cagaagaaga gttgaaacaa
    24121 gtcgttgctt cacttcctgc ctcaccaaaa ccaagcgttc agcgttataa aggacttgga
    24181 gaaatggatg atcatcaact atgggaaaca actatggacc caagcaatcg gatgatggcc
    24241 cgcgtcagtg tggacgatgc tattgcagca gatcagatat ttgaaatgtt gatgggggat
    24301 cgagtagaac cccgtcgtgc attcatcgag gaaaatgcac actatgtgaa gaacttagat
    24361 atttaatcat gaaggaggaa aaagaatgag tgaagaaatc agagaaaaca tccatgatgt
    24421 caatctaacc agcgaaatga aagactcctt catcgattat gcgatgagtg ttattgtcgc
    24481 acgtgcactt cctgatgtca gagatggtct gaaacccgtt catcgccgta ttttatacgg
    24541 catgaacgaa ttaggtgtaa caccggataa agcccataaa aaatctgcca gaatcgtcgg
    24601 agatgtcatg ggtaaatacc atcctcatgg agactatgcg atctatgagt caatggtacg
    24661 gatggcacag ccattcagct accgttatat gctagtggat ggtcatggaa actttggttc
    24721 tgttgacggt gacggtgccg ccgctatgcg ttataccgaa gcacggatga gcaaaatcgc
    24781 tacagaaatg ctgcgtgata tcaataagaa cactgttgat ttccaaagca actatgatga
    24841 tacagaaaaa gaaccagttg tactacctgc tcgcttcccg aatcttttag tgaacggaac
    24901 aacggggatc gccgtaggta tggccacgaa tatcccacct cataacttgt ctgaggtagt
    24961 agcggctatc gatttgctga tggataatcc tgatgtgacg accaatgaat tgatggaagt
    25021 attacctgga ccagattttc caacaggtgg tttggttatg ggaaaatcag gaatccgaag
    25081 agcgtatgaa acaggtaagg gttctattac cgtacgtgca aaagttgaga ttactgagat
    25141 gccaaatggt aaagaacgga tcatcgtgac agaattgcct tatatggtca ataaagcaaa
    25201 attgatcgaa cggatttctg aactgcacag agacaagcgt atcgaaggga tcacagattt
    25261 gcgggacgaa tcttcccgtg aaggtatgcg gatcgtcatt gacatccgtc gtgacgccag
    25321 cgcatctgtt atcttgaata acttatataa attgacatcc ttgcaaaatt catttggatt
    25381 caatatgttg gcgatcgaaa aaggtgtgcc gaaagttttg agcttgaaac aaattcttga
    25441 aaactatatc gaacatcagc gcgaagtcat cacaagacgg acagtctttg aaaaagaaaa
    25501 agcagaagca agggcacaca ttttagaagg tttgcgtatt gctttggatc atatcgatga
    25561 aatcattgcg attatccgcg ggtctaaatc agatgacgaa gcaaaagcga cgatgatcga
    25621 acggttcgat ttatccgatc gccagtctca agctatttta gatatgcgtt tacgccgatt
    25681 gaccggtttg gaacgggaaa aaatcgaaaa tgaataccaa gaactcttaa aactgattga
    25741 agatttaact gacattctgg caagaccaga acgtgttaca gaaatcatca agaatgaatt
    25801 agcagacttg aatcaacgat ttggtgataa acgacgcaca gaattactag tcggtgaggt
    25861 cttaagtctg gaagatgaag atttaatcga agaagaagaa atcgttatta cattgacaaa
    25921 caatggttac atcaaacgtt tggcaaataa tgaattcaga gctcaacgaa ggggtggacg
    25981 tggtgtccaa ggaatgggta tccacaatga cgacttcgtc aaaaatctgg tttcttgttc
    26041 tacccatgat acattgttat tctttacgaa taacggaaaa gtgtatcggg caaaaggata
    26101 cgaaattcca gaatacgggc gcacagccaa aggaatacca attatcaatt tactaggtat
    26161 cgattcgagt gaaagcatcc aggcaatcat tgcggtgacg ggagaagcag aagaaggcca
    26221 ctatctcttc tttacgacgc gtcaaggtac agtaaaacgt acttctgtca ctgcttttgc
    26281 taacatccga agtaatggtc tgatcgcaat tggtttgaaa gaagacgatg agctcgtcaa
    26341 tgtgctactg acagatggtc aatctaatat cattattgga acacataacg gctactctgt
    26401 cactttcaaa gaagaagcag tccgcgatat gggacgtaca gcttccgggg ttagaggaat
    26461 acgcctgcgt gaggaagatt atgtcgttgg ggcagcctta atgaaggaag atcaagaagt
    26521 attagtgatc acagaaaaag gttacggaaa acggacaaaa gtatcggaat atccagtgaa
    26581 aggccgcgga ggtaaaggga tcaaaacggc gaacatcact gaaaaaaatg gtccactagc
    26641 tggattgacc actgtttctg gagatgaaga catcatgctg attacagata aaggtgtcat
    26701 tatccgtttc aacgtatcga ctgtttctca aactggacgt tcaacattag gcgtacgttt
    26761 gatgaagatg gaagctgata cgaaagttgt cacgatggca gcagtcgaac cagaagctgc
    26821 agaacaaaca gttgaagaac aaggatcaga agaatagcca tcaagactaa ttgtgtaagc
    26881 tagcaagaat gaccgattaa aaaatctggt tattcctgct ggcttttttg attagttgaa
    26941 tttctcttaa aatattcgaa actgttcatt ctgtattgct tttgaccaaa atagagtgta
    27001 taatcagagc ttgtgagtag tctaattaat tagataactc tccttgctct taggaaccta
    27061 agagccgaaa gtccacaggg aggtgaatat caatggaaaa cacgaaatat gaaatcatgt
    27121 acattattcg tccaaacatt gatgaagaag caaaaactgc tttaatcgaa cgtttcgatg
    27181 caatcttgaa agataacgga gcagaagtta tcgaatcaaa agattgggaa aaacgccgtt
    27241 tcgcttatga aatgaacggt taccgtgaag gtatctatca catcgttaaa gtatcttctc
    27301 catcatcagc aaatgctgtc aatgaatttg accgtcttgc taaaatcaac gacgatatca
    27361 ttcgtcacat gattgttaaa gaagaagctt aattgttgtt tcatgtgaaa caatagaaaa
    27421 cgatgagagg agatgactat tttgattaat aatgttgtat tagttggacg tctgacgaaa
    27481 gatccagatt tgcgttacac agcaagtggt acggcagtcg caacatttac tttggctgtg
    27541 aatcgtaatt ttacaaacca aagcggcaat cgcgaggctg attttatcaa ctgtgtgatt
    27601 tggcgcaaat cagcagaaac tttagcaaac tatgctcgta aaggaacact tttaggtgtt
    27661 actggacgta tccaaactcg ttcttatgat aatcagcaag gacaacgtgt atacgtgaca
    27721 gaagtagtag ctgacaactt ccaattgctg gaaagtcgtt ctgcatctga aaatcgccaa
    27781 caaagcggcg gattccaaag ttctggtcaa tcagctggcg gatttggcgg aaacaataac
    27841 tctaatcaaa catctcaatc atccaacggt atgcctgatt tcgaccgtga tacttctgac
    27901 ccattcggct caagttcaac gatcgacatt tcagacgatg atttaccatt ctaaacgaat
    27961 ttgataggag ggaaatagaa tggcacaaca aagaagaggc ggacgtaaac gtcgtaaagt
    28021 agactacatt gctgctaacc atattgaata tatcgattat aaagatatcg aattactaaa
    28081 aagatttatt tcagaacgcg gtaaaatctt gccacgtcgt gtaactggta caggcgctaa
    28141 aaaccaacgt aaaattactg ttgcaatcaa acgcgctcgt atcatgggct tgctaccttt
    28201 cgttagcgaa gactaataaa tcctaggaat tgaatgactg atccttttga tcagctattc
    28261 aattcctttt tttctgtaaa aataacctct attcgtttag tcgctcgaat gacgaaagtt
    28321 atggtaaaat caaattagtc atatatggga ggaaaattat ggaaaataaa aacaatcatt
    28381 tatccccgaa acctctcttc cttatcctgt ttatattaat cgaagtattg gtagtcttaa
    28441 ttttaccatt tcgttttgtt agcgcttcgg tcattctatt gatgaattta tggggtgttc
    28501 gctattggtt gaaaatgaaa cgttggctta ttttaaataa acgtgaaaaa atccagcagg
    28561 cttcgactgt agctgaaacc aatctagctt atgtctcaga agtcatgcct gtaggagtga
    28621 ttgcttatca gccatcaagc caaaaaatcg aatggctcaa tccattagca ttgaaaatca
    28681 aagatcaaag tggattaaca gaggaagaat tgctagatac tttttttact gcaaaagaaa
    28741 aaaagaaaaa ccaagtctat ctagcagata aaacatttca gtttgatatg gatacagtaa
    28801 agggtgttgt ttattttaat gatattaccc aaaaccagtt gttaaaactc catcagacga
    28861 acagtcagcc ggtgattggt attttatcta ttgataacta tgcagatgcc attgataaat
    28921 tggatgacaa agagatttct tatttgaact ctttcgtcac tacactagtt tctgactgga
    28981 tgaatgaata ccatgtcttt ttcaaaagaa tcaacgcaga acggtttttc ttcgtagcac
    29041 agatgatcga tctgaaaaag atgatggata aaaaatttga tttgctggat cgctttcgag
    29101 cagaagctga aaaacagagc tcgcctatca cccttagtat ggggattgct tatggctcaa
    29161 gaaccctcga tgaaatcggt ggagaagctc agaataattt agatgttgct ttagtccgtg
    29221 gaggcgacca agttgtcgtg aaagaggtaa aagaaggagc aaaacctgtt tattatgggg
    29281 ggaaatctgc taagaatgtc aaacgcacgc gtgttcgttc tcgagcgatg agtaccgctt
    29341 tgcgtcggat ttttgatgaa acaggcgatg tgtttatcat ggggcacaag tttccggata
    29401 tggatgcttt aggctctgct tttggtgtca gttgtctggc acgcttcaac cagaaaaaag
    29461 cttacatcgt tatcaacgag aacgagatca ttccagatgt agaacggtgt cttgaagaaa
    29521 tccataagca tcctgaatta gaaatgcaac taatctctcc agaacgtgcc atagagctga
    29581 aaaaagaaga ggacctcctc gtgatggtgg attaccataa accttctcta tcgatctctc
    29641 agggcctata tgagcaattt gataagattg tgatcattga tcaccatcgt cgtggggaag
    29701 agtttccaag taaacctctg ctgacttata tcgaatcttc agcttcttca gcttcagagc
    29761 tagtttctga gctgatccaa taccaaagca gcaaaacaaa tcgcttagat cgttttgagg
    29821 ccacattatt gcttgcaggg atggttgtag atacaaatag tttcaatgtc cgtacaactg
    29881 cacgaacttt tgacgttgcc agctatttaa ggtcttgtgg agcagacgca tccttagtac
    29941 aatatttatt gagctcggat ttagcgacat acttggagat cagcaatttg attgctggaa
    30001 gcgactatgt gacttctgat attgttgtgg cggcagggac agacgaaaaa gagtataata
    30061 gtgttatagc agcaaaaaca gcagatacat tgctttcgat gatcaatatc aatgcagctt
    30121 tcgtcattac aaagcggaca gacggcttga ttgggatcag tgccagaagt accggcacga
    30181 tcaacgtcca aatcatcatg gaatccttag gtggcggagg acacttcaca aacgcagcta
    30241 ctcaactgga aaatacgaca gttgaggaaa caaaacagaa gctatttgct gcaatcaaag
    30301 aaaatatgaa tcaaatatat gataaggagt aatccaaatg aaagtaattt ttttacaaga
    30361 tgtaaaagga aaaggtaaaa aaggggacat caaagaagtt ccagcaggtt atgcacaaaa
    30421 ttatctaatc aaaaataact tggcaaaaga agcaacgaaa agcagtatca gtcagttagc
    30481 aggacaaaag aaagcacaag aaaaacacga agctgaaatc ttggaagaag ctaaaaagtt
    30541 aaaagaattc ttggaaaaag aagatactgt agtcgaattg aaggcgaaag caggggaaga
    30601 cagccgtttg tttggttcga tcccttcaaa acaaattgct gaagggttaa acaaacaata
    30661 caaaatcaaa ttagataaac gaaaaatcga attagaaaat ccgatccgtt cactaggcta
    30721 cacaaacgta cctgttaagc ttcatcatga ggtgacggct acgatcaaag ttcatgtcgt
    30781 acaagaataa caaatcttga tagcgatgtt cagctggtaa gtataaccag aaggaaaaaa
    30841 gacaaaccga aatttatctg agaaaacagc tgcagcaatg aaagcaaaag ctgcaaatcg
    30901 atttcagatt gatttcggtt tcttttttgg gaacagcaaa atagcataaa gaaaacgagt
    30961 ataataaaag agaactattt ttttattaca ctttcggtac gaatgatgac ttttctctca
    31021 ttttcttgta aaatgaagca attgaagaca aggagcgata cgtatgaatg aagtgtggca
    31081 ggatcgaatc ccaccgcaaa atattgaagc tgaacaagcg gttttaggct ctgtttttct
    31141 tgacgcagaa acgatcattg atgccatgga gtacatagag ccaaaagact tttatcgtcg
    31201 tggccatcaa attatttttg agacaatgat cgagttaaat gatcgtaatg aagcgattga
    31261 cgtggttact gtcaaagacc ggctggaaca agccaatttg ttagaagatg ccggtggttt
    31321 aagttatctc tcagacttgg cattagcagt tccgacagca gcaaatatcg tctactatgc
    31381 gaaaatcgtt gaagaaaaat cattgctgcg tacattgatc cagacagcaa caggaatcgt
    31441 tacgaaagga ttcgagcaag gagaagaagt tcaaacaatt ttagatgatg ccgaacgcag
    31501 tatcttggag gtttcggaaa aaagaaatcg aagcggcttt ttatctattg ctgaagtact
    31561 gaactccacg attgaaaata tcgatcgact agctcaaaac aatgaagaaa tcacaggtct
    31621 accaactggc tatcaaggtc tggataaaat gacagcaggt ttccagcccg aagaactaat
    31681 cattcttgct gcacgtccag cggtaggtaa aacagcgttt gcattgaata ttgctcaaaa
    31741 tgtaggaaca aaaacagatc gttctgttgc gatatttagt ttggaaatgg gggcagaatc
    31801 tcttgtaaat cggatgcttt gtgcagaagg ttcgattgag gccagccatt tacgtacagg
    31861 tcagctttcg gaagaagaat ggtcgaatct gatcgttgcg atggggagtc tttctcgagc
    31921 aaatattttt atcgatgata caccagggat caaaatctct gaaatccgtg cgaaatgtcg
    31981 gaaactagcg caagaaaaag gcaatctagg cttgatattg atcgattatt tgcagttgat
    32041 tgaaggtaac ggtaaagaga accgtcaaca agaagtatca gatatctctc gccaactgaa
    32101 aaaactggcg aaagagctga aagtacctgt cattgctctt tcacagttat ctcgtggagt
    32161 agaacagcga caagacaaac gaccagtgct aagtgatatt cgtgaatccg gatcaattga
    32221 acaagatgcg gacatcgtag ccttcttgta tcgagatgat tattatgaaa gagaaggcgg
    32281 agatgacgat gatggaaacg agccaaaaaa tgacaacgtc atcgaagtca tcatcgagaa
    32341 gaaccgaagc ggtgcacgag gaacagttga actactgttt atcaaagaat acaataagtt
    32401 ttcgtcgctt tcgccaagag aagaatttta aagaagaggt tgtgagcctt gagcaatccc
    32461 gagagctctc gtaagaagat gcaaggagta accgcaggaa cgactagagt acttaattta
    32521 aacagatctc caaagggatt gtgacaaaag tcttgtcaca gtcccttttt ccgaataaac
    32581 ggtgttcaat cagctgaccc ttggtattag ctcagcaaac gtcaaaatat gaggaactat
    32641 tttgacgttt gtttctctaa tactcaggtc aaaacgctga tcttacgacc tcttttcctt
    32701 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatcatcaa acatgagaag
    32761 cagttttttg aaattgctcc ttgtgactca gagttaaacg gcaggctcac aacctctttc
    32821 ttaaacggtg ttcaaaagct tgcatctgcg gtaatacgcc caatcaaacg aaaaatatga
    32881 gaagctattt ttgtttggct gttcttatta cttgatgcag gacagctttt tcacaacctc
    32941 tgattcacgg tgttccaaaa gtagcttctt cgaaaaataa gtcgaaattt cacaaaaatt
    33001 tgagaagcaa ttttcgtaca ttccttctta tttcttgaag ctgaccactt ctgttacaac
    33061 ctctttttta ataaccattc taaaaagata aagttcgttt tttaagcgtt tttataaaat
    33121 aaaaataaaa atcattcgat tttatttgaa atatgtatct attattgata caatggttca
    33181 ggattaaata atatagaacg aggtgttcac atgtcatctg tagtagtagt aggtacgcaa
    33241 tggggcgatg aagggaaagg aaaaatcaca gactttctca gtgaaaatgc tgaagtgatt
    33301 gcacggtacc aaggtggcga caatgcaggg cacacaatta agtttaacgg tgtgacttat
    33361 aaactgcatt tgattccttc tgggattttt tataaagaca agatcagtgt gatcggaaac
    33421 ggcgttgtag tcaatcctaa atcattggtt aaagaattag cttatttaca tgaaaaaggt
    33481 gtagaaacaa gtaatttgcg tatttctgac cgcgcgcacg taatcttgcc ttatcatatc
    33541 aaattggacc aattacaaga agatgctaag ggcgaaaata agattggtac aacgattaaa
    33601 ggaatcggac ctgcctatat ggataaagca gctcgtgtag gtatccgtat tgcagactta
    33661 ttagataaag aaatttttga agaacgtctt cgtttgaatc tagatgacaa aaaccgtcaa
    33721 tttgtaaaaa tgtttgattc agaaccactt gattttgacg atatttttga agaatattat
    33781 gaatacggac aacaaatcaa acaatacgtc acagatactt ccgttatctt gaatgatgct
    33841 ttggatgcag gcaaacgcgt gttgtttgaa ggcgcacaag gtgtaatgct ggatatcgac
    33901 cagggaactt atccttttgt tacttcttct aacccagtag ccggtggggt aacaatcgga
    33961 agcggtgtag ggccttcaaa aatcaataaa gttgtcggcg tctgcaaagc ctatacgtca
    34021 cgtgtcggtg atggaccatt tccaactgaa ttatttgatg aaacaggaga acaaatccgc
    34081 gaagtaggac gagaatacgg tacgacaact ggtcgtccgc gtcgtgtagg ctggtttgat
    34141 tctgtagtta tgcgccattc taaacgagtt tcaggtatta ccaacctatc tttaaactcg
    34201 atcgatgtat taagtggatt ggaaacagta aaaatttgta cggcttatga attagatggc
    34261 gaactaatct accactatcc agcaagcttg aaagagttga accgctgcaa accaatctat
    34321 gaagaattgc caggctggtc agaagacatt acaggatgca aaacacttgc agaactgcca
    34381 gaaaacgcac gtaactatgt acgtcgtatc tcagagcttg ttggtgtacg tatctcaaca
    34441 ttttctgtcg gacctgatag aacacaaaca aacatcttag aaagcgtctg ggcgcaaatc
    34501 taaggataaa aacgacgact gaatcaggac gttcttacca gagcgagtcg aagtgtttat
    34561 ctatacgata ataataactt gaacactgtt tattcagaat aagggactgt gacaaaaacc
    34621 gtgtcacagt ccctttttcc gaa
//
LOCUS       DADVXM010000022        34585 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.023, whole genome shotgun sequence.
ACCESSION   DADVXM010000022 DADVXM010000000
VERSION     DADVXM010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.023"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            212..604
                     /locus_tag="KB927_001143"
     CDS             212..604
                     /locus_tag="KB927_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6840076.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="KB927_001144"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="KB927_001144"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBB6840077.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3164..4774
                     /locus_tag="KB927_001145"
     CDS             3164..4774
                     /locus_tag="KB927_001145"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBB6840078.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5066..5935
                     /locus_tag="KB927_001146"
     CDS             5066..5935
                     /locus_tag="KB927_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBB6840079.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6100..7371
                     /locus_tag="KB927_001147"
     CDS             6100..7371
                     /locus_tag="KB927_001147"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBB6840080.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7368..8663
                     /gene="rho"
                     /locus_tag="KB927_001148"
     CDS             7368..8663
                     /gene="rho"
                     /locus_tag="KB927_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBB6840081.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8762..9025
                     /locus_tag="KB927_001149"
     CDS             8762..9025
                     /locus_tag="KB927_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBB6840082.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9470..9919
                     /locus_tag="KB927_001150"
     CDS             9470..9919
                     /locus_tag="KB927_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6840083.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9976..11394
                     /locus_tag="KB927_001151"
     CDS             9976..11394
                     /locus_tag="KB927_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6840084.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSISTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11394..12254
                     /locus_tag="KB927_001152"
     CDS             11394..12254
                     /locus_tag="KB927_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBB6840085.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12428..13201
                     /locus_tag="KB927_001153"
     CDS             12428..13201
                     /locus_tag="KB927_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6840086.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13348..13713
                     /locus_tag="KB927_001154"
     CDS             13348..13713
                     /locus_tag="KB927_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBB6840087.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13861..15069)
                     /locus_tag="KB927_001155"
     CDS             complement(13861..15069)
                     /locus_tag="KB927_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6840088.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15088..15366)
                     /locus_tag="KB927_001156"
     CDS             complement(15088..15366)
                     /locus_tag="KB927_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840089.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15520..16215
                     /locus_tag="KB927_001157"
     CDS             15520..16215
                     /locus_tag="KB927_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6840090.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16657..17454)
                     /locus_tag="KB927_001158"
     CDS             complement(16657..17454)
                     /locus_tag="KB927_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBB6840091.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17451..18635)
                     /locus_tag="KB927_001159"
     CDS             complement(17451..18635)
                     /locus_tag="KB927_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBB6840092.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18660..19907)
                     /locus_tag="KB927_001160"
     CDS             complement(18660..19907)
                     /locus_tag="KB927_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBB6840093.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVCPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20122..21867
                     /gene="dnaX"
                     /locus_tag="KB927_001161"
     CDS             20122..21867
                     /gene="dnaX"
                     /locus_tag="KB927_001161"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBB6840094.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21887..22201
                     /locus_tag="KB927_001162"
     CDS             21887..22201
                     /locus_tag="KB927_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBB6840095.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22226..22822
                     /gene="recR"
                     /locus_tag="KB927_001163"
     CDS             22226..22822
                     /gene="recR"
                     /locus_tag="KB927_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBB6840096.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22886..23530
                     /locus_tag="KB927_001164"
     CDS             22886..23530
                     /locus_tag="KB927_001164"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBB6840097.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23545..23874
                     /locus_tag="KB927_001165"
     CDS             23545..23874
                     /locus_tag="KB927_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBB6840098.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23888..24826
                     /gene="holB"
                     /locus_tag="KB927_001166"
     CDS             23888..24826
                     /gene="holB"
                     /locus_tag="KB927_001166"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBB6840099.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24862..25686
                     /locus_tag="KB927_001167"
     CDS             24862..25686
                     /locus_tag="KB927_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBB6840100.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25679..26026
                     /locus_tag="KB927_001168"
     CDS             25679..26026
                     /locus_tag="KB927_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBB6840101.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26095..26967
                     /gene="rsmI"
                     /locus_tag="KB927_001169"
     CDS             26095..26967
                     /gene="rsmI"
                     /locus_tag="KB927_001169"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBB6840102.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27076..28197
                     /gene="dinB"
                     /locus_tag="KB927_001170"
     CDS             27076..28197
                     /gene="dinB"
                     /locus_tag="KB927_001170"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBB6840103.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="KB927_001171"
     CDS             complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="KB927_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBB6840104.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="KB927_001172"
     CDS             complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="KB927_001172"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBB6840105.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIAEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31656..32450
                     /locus_tag="KB927_001173"
     CDS             31656..32450
                     /locus_tag="KB927_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840106.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32440..34482
                     /locus_tag="KB927_001174"
     CDS             32440..34482
                     /locus_tag="KB927_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6840107.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
BASE COUNT        11116 a         6130 c         7259 g        10080 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga atttcggctc cctattctta ttgaagaata gggagctttg tttattgtct
     3121 gagacttttc ctgcacataa attaaaaagg agtttttgaa cttatgacaa aatatatttt
     3181 tgtgaccggc ggtgtcgttt catcaatcgg aaaagggatt gttgcagctt ctttaggacg
     3241 cttattgaaa aaccgcggct taaaagtaac tatccaaaaa tttgatccat acatcaacgt
     3301 ggatccgggg acgatgagcc catatcagca cggagaagta ttcgtaacag atgatggtgc
     3361 tgaaacagat ttggatctgg gccactacga acgttttatt gacatcaatt tgaacaaata
     3421 ctccaacgtg acgacaggaa aaatctattc tgaagttttg cgtaaagaac gtaagggcga
     3481 atacttggga gcaactgttc aagttattcc tcatattaca aatgagatca aagaaaaaat
     3541 catgcgagca gctaaaatga ctgattcaga tgtgatcatt acagaagtag ggggaacagt
     3601 aggggatata gaatctttgc cattccttga agcacttcgt caaatgaaag cagatgtcgg
     3661 tacagataat gttatgtata tccatacaac attgattcct tacttgaaag ctgctggaga
     3721 aatgaaaact aaaccaacgc agcacagtgt aaaagagcta cgtggtttag gtatccaacc
     3781 gaatattttg gtggtacgta cagagcaacc tgtttctcaa agcgtgaaaa acaaattggc
     3841 acaattttgt gatgtcgaac cagaagcagt tatcgagtcg ccagatgtag atacacttta
     3901 ctccatccca ttagttttac aagcacaagg aatggatcaa attgtttgcg accatttaaa
     3961 actagataca ccagaagcag acatgacaga atggaaagaa ttagaagaac gtgtcttgaa
     4021 cttgaagaaa aaagtacgga ttgcgcttgt cggtaaatat gtcgagttac cagatgcata
     4081 tatctcagta gttgaagcat tgaaacattc tggtttcgcc tataattcag acatcgagat
     4141 cgattggatc aaagcacaag aattaacgag agaaaatgta gaagaacgtt tgaaagacgc
     4201 agatggaatc ttggttcctg gtggatttgg tgatcgcgga gtagaaggga aaatcgaagc
     4261 gattcgttat gctcgcgaaa atgacgttcc gtttttaggt atttgtcttg gtatgcagat
     4321 ggcttgtgtc gaatttgcac gtaacgtcgt tggattagaa gatgcgtcat cagctgaaac
     4381 gaatccagat acagcaaaca atattattga tttaatggct gatcaggaaa acatcgagaa
     4441 tttgggtgga actttacgcc ttggattata cccatgtaaa atcaaaaaag gaacgaagac
     4501 ggctgaagca tatgatggag ccgatgttgt gcaagaacgt caccgtcacc gctatgagtt
     4561 caataacaaa tatcgtcaat tgtttgaaga acaagggcta gtcttttcag gtgtctcacc
     4621 agataaccgt ttagtagaaa tcgtagagct gccagagaaa aaattctttg tgggatgcca
     4681 attccaccca gaattgattt ctcgtccaaa tcgcccgcaa aaattaatca aagcatttgt
     4741 cggagcatca ttagcagatc acgaaacaaa ataatttttg aacttgatag aaagagaaaa
     4801 gtagcaagag aaggggataa gcaattttct tgtcactttt ctctttttct gatttgttat
     4861 tatttgtagg aaaaaagata gaaagcaaaa gacttttttc gattaaagcg ctattggata
     4921 ttttattttt tgcaaaaaac ttcttgaaaa ttttcatttt cattgatttt agtagaaaac
     4981 taccgaaatg tttggtaaaa tagggtcgtt ggttaagaat tgtcttaaca aatttagttt
     5041 tacaaaactt aggaggaatt ttattatgcc agtagtatca ggagctgaat ttttaaaagc
     5101 tgctcgtaaa ggcggttacg ctgtcggcgg attcaacaca aacaacttgg aatggactca
     5161 agcaatcctt gaagcggctg aagcaaaaca agcaccagta cttatccaaa catcaatggg
     5221 tgcagctaaa tacatgggtg gttacaaaat ctgtaaagat ttaatcactg atttagttga
     5281 agcaatgaac atcactgttc cagttgctat ccacttagac catggtgatt acgaagctgc
     5341 tttggaatgt atcgaattag gctatacttc agtaatgttc gatggttcac atctaccatt
     5401 tgaagaaaac ttgaaattag ctaaagacgt tgttgaaaaa gcacatgcaa aaggtatctc
     5461 agttgaatgt gaagttggtt caatcggcgg agaagaagac ggaatcatcg gtaacggcga
     5521 attagctgat attgaagaat gcaaacaaat ggttgctaca ggtatcgact acttagcttg
     5581 cggtatcggt aacatccatg gtcaatatcc agaaaactgg aaaggattag cttttgacca
     5641 cttacaagca attgctgatg ctgtaggtcc agacatgcct ttagtattac atggcggatc
     5701 aggtattcct caagatcaaa tcgaaaaagc tatctcaatg ggtatctcaa aagtaaatgt
     5761 taacactgaa ttccaattat catttgctgc agctactcgt aaatatatcg aagctggtaa
     5821 agataaagaa ggtaaaggat tcgaccctcg taaattatta gctccaggta aagcagcaat
     5881 cgttgaagat gctaaatctc atatcgactg gttcggttca gctaacaaag cgtaagcatc
     5941 cacataacag atacgatata taggaatgga gaacgacttt tgaagtcgct ctccattctt
     6001 ttttacttaa aacggcagac catgctcgtt tctttttttt atctatgata aaatacaagc
     6061 atatccatga aaaaagatta ataaacaagg tggaaacaga tgaaaaaaat cgtaatcaaa
     6121 ggaaaccgac ctttagctgg tgaagtaacg atcagcggtg caaaaaatag tgcagtcgca
     6181 ttgattccag ctgcaatctt agctgattcc ccagtgatct tggaaggtgt gccggacata
     6241 caagatgttc attcattaat tgaaatttta gagatcatgg gcgcaactgt ccatttttcc
     6301 aacaacatac tagaaatcga tcctcgagaa gtcgtatcga ttccgatgcc gcacggaaaa
     6361 atcaatagtt tgcgtgcttc ttattatttt atgggaacac tgcttggtaa atttggcgaa
     6421 gcggtagtag gcctgccagg tggctgttat ttaggcccta gaccgattga cctacacgtc
     6481 aaaggatttg aagctctagg tgctgaagtg acaaatgaac atggtgccat gtatttacgg
     6541 acagaaaata aaggattgcg tggcaatcgg attttcatgg acgtggtttc agtcggagca
     6601 acgatcaatg tgatgttagc tgctgtaaaa gcaaaaggac agacagtaat tgaaaacgct
     6661 gcacgagaac cggaaatcat agatgtggca actttactga ataatatggg ggcaaaagtt
     6721 cgaggagcgg gtacagatgt gatccgtatc gaaggagtcg aaacattaca tggctgtcgg
     6781 catttcatga ttcctgaccg catcgaagca ggaacctatc tagcattagc agctgcagta
     6841 ggaaatggta tcaaagtgaa aaatgtgatc tttgaacatt tggaaagctt tatagcaaaa
     6901 ttgcaggaaa ttggtgtcca tatgaaaatc agcgaagatg aaatcgaagt ttacccctcg
     6961 aaagaattaa aacccgcaaa catcatgacc tatccttatc caggatttgc cacagatctg
     7021 cagcagccac ttactgcgtt actattgatg actacaggca cttcagaaat catcgatacg
     7081 atctatgcga aacgtgtgaa ccatgtgccg gaactagcac gaatgggcgc tgatattacc
     7141 gtggaaggaa atatgatcat cgtgaatggt ccaaataaac ttcacggcac agaagtcgtg
     7201 gcttctgatc ttcgggcagg tgcttgttta gtgattgctg gactattggc agaagggaca
     7261 acgacgattt acaatgtaga ttatatctta cgcggttatg atcatattat cgagaaacta
     7321 acagccttag gggcatcaat tgaaatgata gaggaagtgg gagctgaatg agcgattatt
     7381 tgacaatggc agaactagag aacaaaacgt taaaagaagt ttatagttat gccaaagaat
     7441 ttaaaattcc ttattacagt aagatgaata aaaaggaatt atctctagct gtgattcgtg
     7501 cacaagcaga gaaacaagga ttttattata tggaaggaat attggatatc gttggtcaag
     7561 atggttacgg ttttttacgg ccaatcaatt atggaccaag tgcagaagat atctatattt
     7621 ctgcctcaca aatcagacga ttcagtttga gaaatgggga caaagtggca ggaaaagccc
     7681 gtccacctaa agaatcggaa cgttattatg gtttgatgca cgtggaaagc gttaatggaa
     7741 aagatccgga agaagcaaaa gaacgtccgc attttccagc cttaacacct ctttatccgc
     7801 aaagacagct tcaactggaa acaacaccgc aaagactatc tacccgaatg atcgatatct
     7861 tttctccaat cggttttggt cagcgtggat tgatcgtcgc accgccaaaa gcagggaaaa
     7921 cttctgtatt aaaagaaatc gcaaatggta tcaccgaaaa ctatccggaa gtagaattaa
     7981 tcgttctact gattgatgaa cgaccggaag aagtaacgga tctagaacga agcgtgaaag
     8041 gcgacgtggt atcttctaca tttgatctgc agccgcaaaa ccatactcga gtttctgaat
     8101 tagtattgga acgcgcaatg cgtttagtcg aagataaacg agatgtcgtt atcttgatgg
     8161 atagtattac tagacttgct cgggcctata acttagtcgt tccaccaagc ggacgtacat
     8221 tgagtggcgg gattgaccca gccgcattgt ataaacctaa gaaatttttc ggggcagcaa
     8281 gaaacatcga agaaggtggc agtttgacga ttttagcgac cgctttagtc gatacaggaa
     8341 gccgtatgga tgacgtgatc tatgaagaat tcaaaggaac tggaaatcta gaattacaac
     8401 tttcacgtga attatctgaa cgtcggatct tcccagccat cgatatcaaa aaatcaggta
     8461 cccgaaaaga agaattattg atgccaagtg aagaattaga agaaatttgg aaacttcgaa
     8521 aaaatatgac tggagattca ttagaatata cggaacaact gatccgcttt ttgcgtaaaa
     8581 caaaaaacaa tcagcaattt ttcaaagaat ttcaagatgt ctcctttggt aaaaaaaatc
     8641 cgaccagaaa tctgaaaaga taattgcaac cttgactgaa acatgttaag atgttaatgt
     8701 tgtaaatcga caaatcaact ctggttcagc aaatggagca gggcaaagga gcgaaaaaat
     8761 catgaaagaa aacatccatc cagattacca cccagtagta ttcatggatt caacaactgg
     8821 tttcaaattc ttgtcaggtt caacaaaaac ttcacaagaa acagttgaat gggaagacgg
     8881 taatacatac ccagtcatcc gtgtcgaagt aacttctgac tcacatccat tctacactgg
     8941 acgtcaaaaa ttcacacaag cagacggacg tgtggaccgt ttcaacaaaa aatacggtct
     9001 caaagacgca aacgctgcgg aataataaaa acgctgataa ctcaacgttt agcagactat
     9061 ctgataggga tagtctgttt ttttatgttt tttgccaatt taaaacttcg tttgatgctg
     9121 aaaaagtcgt aggatcataa tgcacaaaac aatgaaaaac tagtatatag ttttaattat
     9181 ccacttgata aaaacacctt atattaacga aatgaagagg ggttatttcg aagtaaaaaa
     9241 ccatttacct aaaattagaa gctaagcttt cctttcaagg aaggcttttt gttttgttat
     9301 agacttgcga ttgtttgtga gctagatcgt tcattttaat gacttataca cgcggatgat
     9361 gggtcttttt cctctgttca ttcataatat tgaacggtac agctagcgat gctatactga
     9421 cctcagttcc aagaaaacgt taacattttt tgtgggggag aggtttttta tgaggtttga
     9481 tcaattgatc gcagaagaac tgattgtttt cgatccatcg atagattcaa aaggatcatt
     9541 atttgagcga ataggggatg tgttgaaaaa aacaaataag gtaagaaatg ttcaaaaagt
     9601 cgttaaggca ctattcaaac gagaggagga gatctccaca ggaatagaag atggatttgg
     9661 gattccccat gcaaaaagca aatatgtgac aaaaccagca ctgtgttttt ttcatacagc
     9721 caaattaacg gactatagcg ggatagatga aatgccaatt gaatatattt ttgccatcgt
     9781 agttcctgaa aaatcagcag atatgcatct agagattctc agcacactct ccagacgatt
     9841 gatgaatgca gattttagaa agggaataaa agaagccact acgccagcag atatcatcag
     9901 acagattagt caagaatgaa aatagtagag tctttgtccg agtatcgata gtgaagaaaa
     9961 aggaggaaaa taatcatgaa aatcgttggt gtaactgctt gcccgactgg aattgctcat
    10021 acttatatgt cggcagaaaa attagaagta acagcaagaa atctaaacca tcaagcaaaa
    10081 ttcgaaacac aaggtgtaaa aacagaaaat cagttatctg aacaagaaat caaagaggca
    10141 gatgcaatca ttcttgcagt agataaagaa atcgaattgg accgatttgc cgggaaaaaa
    10201 gtaaagcgtg tctctacaag ccgagcaatc aaagaaccgc aagtagtaat agacgaagca
    10261 ttgagagata ttggcgtatt cgttgtgtct aatgaaaaag aaccagctgc aaatgagaaa
    10321 aagccgacaa tctataatca tttcatgaat ggtgtgaatt acatgcttcc atttgtgatc
    10381 gcaggcggaa tcatcatcgc actgagtttt gcctttggga ttacagcggc tgatcccaac
    10441 tcagcagact ataatgtgtt agcagctgca ttttcaagga tcggaggaga tacagcgttt
    10501 gccatgatgg ttcctgcgtt aggcgcgggg attgctacat cgattgctgg aaaagcaggt
    10561 tttgccccag gaattgttgc cggattactg gcctctacag gtggttcagg ttttcttggc
    10621 ggaatgattg gtggcgtgct agcagggtat atctgtgatt ttctggcaaa taaaattagc
    10681 gtaaaaaaag aattttctgc tatttatcag ctgattgtcg tccccttttt atcgatctta
    10741 attattgggc ttttgatggt atttgtgatt gaacaaccga tcacatgggt gttggatgct
    10801 ttgacaaatt ggctgaatag cttgggaaat acatccgggc tattgttcgg attacttatc
    10861 gggatcatga tggcagctga tatgggtggg ccgatcaata aatcgatttc gactttctcg
    10921 atcggtttga tgtcagctgg agtaaatgca ccgattgctg cttgtatggc tgcaggaatg
    10981 acacctcccc taggtattgc tttagccact ttattattca aacataaatt taccaaagaa
    11041 gaacggactt caggtcaatc atgctggatt ttaggcgctt cgtatattac agaaggtgct
    11101 ataccgtttg cggtatctga cccgatccgc gtgataccta gtttgatgac aggttcagca
    11161 gtcgctgcag ggatttccat ggcagtagga gttacttcaa tggcacctca tggagggatt
    11221 tgggtgatgc taattccaaa tgttatgaac aatttaccta tgtatgtctt ggcaattgca
    11281 tcaggtacag tcactacagc ctttatgctt ggactattga aaaaaacagt gaaagagaaa
    11341 aaacaagaca agtggacgaa aaatgaaaat ctaacaaatg aggtggaagc gtaatgttat
    11401 atacaatgaa agagttattg aaagtggcta aagagaatca atttgcagta ccagccttca
    11461 atatttgcag ctatgatatg atgaaagcaa tcatcgaaga agcagagaga ttagaagcac
    11521 cagtaatctt agaaattcat cctgatgaaa tcgcctattt aagtgatgag tttgttgcgg
    11581 cagtaagagc ctatgcttat acaagtaaac tgccgatcgt tatccacttg gatcatggcg
    11641 gtacgataga agatgtctta cgggcgattc gaaacggcta ttcttccgtg atgatcgatg
    11701 cgtctttgaa atcattcgac gacaatgtac agattacgaa aaaagtggtt gcgttagctc
    11761 atgcggtaaa tgtctcagtg gaggctgagc ttggaacgat tgggaataat ggttctgctg
    11821 aaggaggtgc tgaaacaatc atttatacag atcctgatca agcgaagatt tttgtgaaag
    11881 aaacaggaat cgatacactt gctgtagcaa ttggaacagc gcatggcttg tatccgaaaa
    11941 acagaactcc aaaattaaat atcgacttac tgaaagaatt gaaccaacaa atcgatcttc
    12001 catttgtttt acatggcggt tcaggtaatc cggacgcaga agtcagcgaa gcagtaaaat
    12061 acggagttgc caaagtgaat ttgagctcag atcttaaaag cgtctttttc aatgctttga
    12121 gagaaatatt gagtgaaaat ccatcgatgt acgagccgaa tgcaatttat ccagcagcta
    12181 ataaaaaggt acaagaagta gtcaaacata aaatggaaat tttgaacaca gtaggcaagg
    12241 ctagtttata ctaaaaataa aaatgtgtgg tcaagagggt atgacaatag tcttgtcata
    12301 ccctcttaac cacacacgat gttcagaagt agttttttcg aaaaatttct tcttatttct
    12361 cgaagccaat cacttctgtc acaacctctt ttttcctgtt actatataaa gtaaatgggg
    12421 tgattttatg ttgaatgaag tggagaatag acagcaggag attgtgaatt atctaaaaaa
    12481 caaccaattt gcaagagtca ccgatttgat cgagttagta aattatagcg aagccacgat
    12541 taaacgtgac cttgtttttc tggaaaaaag tggattgatc cgtagagttc gcggtggcgc
    12601 catgcttatt gacaatcgaa aaattgacgt gccttacctg atgaagatca ccaaattaga
    12661 agaagaaaca gaaaaacgta agattgcaga tacagcttct tctttgattc gagatgatat
    12721 ggtcttattc ttggattcca gtacaacctc tttacactta gtcagaaacc tagcaagatt
    12781 tgatggtttg cagatcatta cgaatggcat cgtcacagct gctatgttga gtgaatatac
    12841 aacggcaaaa gtatctgtat tgggaggggc aattgttccg aaacgagcaa caatcaacgg
    12901 ttcaaaagcc tataacgatg cattgtcata ttatgcggat ttagcgataa tgagttgtcg
    12961 cgggctagat ttcagccaag gagtaacaga aactcatgaa ggagaggcaa tggtcaaaaa
    13021 agcttttaga aaacaatcag accggcttgc cgttttagtt acacagcaaa aaattgcaca
    13081 taaattcatg catcaagcca ttgcttttca tgaaatcgat tatctggtga caagtaaaga
    13141 actgacaaaa gaacagtatg cgaaagtaaa ggaacaccat atcgaatgtc tgtacggata
    13201 aattattacg tgaatgttct aagtggcttc ctcattttta gataggacct tatctttgct
    13261 cgcttctctc agccgatggt ataataatga aaaggttatc ttgttagata atcttacttt
    13321 tttatccagg agaaaggagt gcagaaaatg aaacatgtga aggcgttggt agtgaaggca
    13381 atcatgatct gggcgattct gtgggtcgtg ctgacaggtt tatacggtgt tagctttatg
    13441 gattcaacga ttgttggggt aattattgta gtcatgatct atgtgctagg ggatctgttg
    13501 atcttacgta aagtagggaa catcgcagcg acgatcgcag atgctggttc agctgcagtt
    13561 atcttgtggc tctatctata ttttatgaat gatacagtcg atatttggat gaaagtattg
    13621 attcctgctc tattgatcgg tgtggcagaa tggttcttcc acaagtggtt gctaagtcaa
    13681 ggcatcgtac cagatgaacg gaaaatggaa taaatcaaca gttaaactat tcttatcgat
    13741 aaatgaaagc tttaaaaata aatagatgtt taattaagaa taatcataaa ctatttttac
    13801 tcaaaaaacc gctcagatta ttttcagatc tgaacggttt tttttatcta ttcatcaaga
    13861 tcaaatttca tttttcaatg attcaatcaa ttcgccctct gcttcatgac tatgttttcg
    13921 gccattaaca agatagagtg ctgtacatat caatggaatg actccggcaa tcacatacaa
    13981 tcctctaaat gaagtaagag attttagcat ccccatcaaa taaggaccaa cgcctaagcc
    14041 taggtctaaa ccaataaagt aggtagataa agcaatactg attcgatgtt cgcggacgat
    14101 ttttaaacaa acagcctgtc catttgacat aaacgtacca taacctaggc cgactaatgc
    14161 tccagagata agcaatgtca cactattcgt cgttacactc agtaaaaata atcctgctgt
    14221 taagaataaa tagctaggat acatcacgta ttgttctcct ttgacatcga aaatccttcc
    14281 agtcaatgga cgtgtaaatg tgatgaccaa agcatatacg acgaagaaaa atgacccagc
    14341 agcaactaag tggattactt ttgtataaga agataaaaat gataaaacac ttgaataaga
    14401 aagacccatc aaaaaggcaa ttcctgtaat gaaaagtgct ttcttttcaa taaaactatt
    14461 gatattccat gagcgaagag atattttttg ttcttcagat aatggaatat tttttacagg
    14521 aaagacaagg caggcaatcg taacaaagaa gaccagtaca attgaaaacc agataatgaa
    14581 acgaaaatca gtcatattca gcaaaatcat tcctaaaaat ggcccaacag cggcagctaa
    14641 actagtactt aatccataat aattgatgcc ttcccctttt ttagatgcag ggatatatgc
    14701 agtaacgata gcatttgtag ctgtagaaac tgtaccgtag ccgaatccat tcaagaatcg
    14761 aactaaatac aatgccccga tagttggcgt ataaagatat gctaatgttg aaaggagata
    14821 gaagatcgcg ccgcctctta aggtaaactt ccgaccaaat agttctaact gtttccccat
    14881 gaataagcgt gccagcaatg ttccgatgat atagatccca gaagcaaaac ctgcttggct
    14941 caagctggcg tgtaaggtgt cttgcgcaat gactgccatg atgaccatca acagataata
    15001 aatcaggtag acaataaaat tgatcaatgt gattccaata aaatatttat taaataattt
    15061 cttttccatg tatgttatac attcccctta agctgaatat gcttttaatt tttgtatttg
    15121 aacttctaca tcgtgataat tggatggata gcgatcaaca agttggcgaa taaataaatc
    15181 tcttgtagac ataaacagat ttaaaaattc ttcgcattcg tttgttggat tctcatccac
    15241 tgctttgatc aattcgatcg agttttgata cgcatcattt aaaaagacta aagaagcttt
    15301 catatcaaat cttgtttgat atgctgtttc taatcgatta atgattgtgt tcatccagta
    15361 attcatgttt tttccctcta ttcttaaaaa attttacttc tgcagtataa cgaataaaaa
    15421 aaaggaaaaa aatcgcataa gtgatggaaa aaggtactta acaaatgtta atatcattag
    15481 taaaatacct ttggacttta aaaagtttta aagtactgta tgatcttttt agatgaaagt
    15541 ttggatgggg gagcatcatt ggatagtaga gtcttaaagg aatatttgga taaaaatgat
    15601 tttccgatta tacgcaaagg atatcataaa tatttgacat tcgaagggat ggaagattcc
    15661 catacgtata tcttgaaaga gggaacggta aaagcaagtg ttatttcaaa tgatgggaga
    15721 gaatttaacc ttcgctatat caaagatctt gaaatcgtct ctcttttaaa agacgaatat
    15781 tcacaattca tcgattcgcc gtataatatt cgagttgaat cagaatatgc agagttttat
    15841 cgaatcaatc gtgtgcgctt ttggcaaaat atcaaccaag acccaaagct acaacactat
    15901 gtaaaagagt attaccgcta tcgtctgctt tattcgatga aaaaaatgca gcaaatgcta
    15961 ttaaacggaa agctgggagc tgtttgtacg caactttacg aattatatga tttattcggt
    16021 gtgcggacag aagaagggat gctgatcgat ttttcgatca cgaatgaaga aatcgccaaa
    16081 ttttgtggca tctcaactgc tagcagtgta aacagaattt taaaacaact gaaaaaagat
    16141 ggtattatca ccgttaaaga ccatcatatc gttattttga atatggactt gttagaagac
    16201 aatattatct tttgatgaac aaagaggttg tgaaatcagc gttttgacct gagtattaga
    16261 gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
    16321 agctgattga acaccgttta ccaagaggtt gtgagcctgc cgtttaactc tgagtcacaa
    16381 ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg tgaccgagga
    16441 gttggtagga gaacaccgtt taccaagagg ttgtgaaaaa gctgttctgc atcaagtaat
    16501 aagaagagcc aagtaaaaac agtctcttat gtttttaact tggctggact tatcaccgta
    16561 gatgtaagct tttgaacgcc gtttatttgc aacaaaaggg gctgtgacac gatttttgtc
    16621 acagcccttt ttttgcgaac attcatttag caatttttag aaacttctgc cgccaccgcc
    16681 aaaagtcccg ccaccgctag aatgggtagt acttccgcca ccgccgcttc caggaggtgg
    16741 gcttttgggg attcttcttg tcgtgacaaa agaatttgtc agacgatcgg ttttttcagt
    16801 taatttgata ctggattttt ctcggaatgg atatttgtag atgcctgatt tcaattgata
    16861 acgcgaaaca gtcacaaaat aaaagacaag actaaggata agagccaaaa caacagcaat
    16921 gatgatttct actgtcgtca aaaccttata gcgtgtaatt ttgccagttt cttcgtctac
    16981 acgataatgt cctcctggaa ctccgtcttc cacatatgtt gctgatttag acaggtaagc
    17041 ttttgcagca ttgtaatagg cagcatttgt catctgatca taaacatcat ctaagatcga
    17101 atcgattctg ctatcagtca aataatcgat catattacca gaagtcgaaa tgtagatttc
    17161 acgctgtccc atatctaata gcaatactga gccattttga tcatttccga ctgcgtctct
    17221 taagtaatta tcagcaaagt ctcttggttc ttctgaatta gatgtagtcg ttacgatcaa
    17281 gactcgtcct ttgatttttt cattcagctt ttctgcctgt tgttccaaag attggatttg
    17341 atctgttgtg aataacccag cctcatcatt taccgtagct gtatctgcat gagtagccac
    17401 cggccagcca acacttacta gcaaaagaaa gaataaaaaa aattttttca tcatatcaag
    17461 taacctccga tcagaaagag gatcgctagc ccagcgaaaa tcccaagagc ggtcagtccc
    17521 aattttttct ggctgatcgg caggacaccg ctgacctttc ctgtttgtcc attcattgcg
    17581 tagtagtaga cttttttact tgagtcattg cttcgataag taacaagcca taccggcagt
    17641 aatacgtaat tatttacttc gtttgtgatt gaagcagaag ttcgcacacc ggtcaatgtt
    17701 gtatatccat ttgcggtatc ttttaacagc ttctctgaat agtcttttaa ttcagattga
    17761 atctgtgatt tgattgcctc atattcgata tctctttttt ctgcttggaa cccggctaaa
    17821 tactggcttt taaaatcaat tgctttatct aacgggaaag gttgcacgcc ttcgaccatc
    17881 ttttgttgcg tattttttga taaggcattt tttactagtt ctttaaaaga aagcttgcct
    17941 gctcttgaaa cagcaaattg cttcgtttct gtgtattcga tgtcacctat ccgccatatg
    18001 cggataactg taccattcgc ctgcatggca ccatctactt cagcatctgt agcccaataa
    18061 gggaaataca cacctgtcaa cttatcgatt tgatccttat tgaaaaaagc tttgggaaca
    18121 aaccattttt tcttggtcca agcgagaaat ctgttgattg cttcttcttt ctcgacagca
    18181 aaaggaagta ctttatttgg caagaattct ccgcttaaac gtcccgatag tacgacggga
    18241 ttatggcagt agtaacaata agtcgcagca gttgtcgcat cagtcacgat ctctgcacca
    18301 cagttgggac aaagaaaaag atctatcgct gcggtattat ctgcagattc gtccgctgta
    18361 tctgaaaaac cgcctgcctc gtcaaccgct ttgcgctcgg cttcattcat atcggcaagc
    18421 tgttcttggg ctgtaaaagt aaaatcttcg gtaggtgaag gttcttcttt gctttcttcg
    18481 ccagccatac gcgcttcttt ttgcttttgc tcatattggc tgacttcttc ttctgtatag
    18541 atattcaggc agtattcgca atgaaatttt tggtctttgg gatcaaaagt caacggaccg
    18601 ccgcaattag gacatttatg tgtaagaaca tccatcagct gcacaccttt ctaaataaat
    18661 taattaacgg ggattccttt aaacggttta ccacagtttg gacagaattt agggatgccg
    18721 ttggaaagat ccacgatctc attgcattca ctgcatcgca tttgtagctt aggctgaacg
    18781 ttttctacag gtttggcagc tccgcagttg gaacagaatt ttccggaatt ttctgtcccg
    18841 caaactggac atgtccaagt atccgcattt ccttgtgcag tttgttgatt ttgtttttct
    18901 gcttgttgtt tgatttgttc ttggttattt tgagctgctt gagaaagata agaaccattt
    18961 gcattcattc ccatacctac acccataaag ccggtcattg ctcctgcttc attttttccg
    19021 gctgcttcca taccacgtgc aatggaacct tgcacgtatc cttcacgtac gctaggatca
    19081 cctagcatcg ccccttcgtt acgcatattg atcagtttca cagaatcatc ggtgtaagaa
    19141 atgctggcta cagccacaga aacaatctcc atcccacgta attcacgcca agaatcatcc
    19201 aatgcagtat ccatgtattt gcttaattcc aaactcttag atggtacata agaaatccgt
    19261 tgaccatctg cagacatctg attgattgct gattgtagcg ctgttaggaa ttcagctaaa
    19321 tactgctcat tgatatcatt gatttccact tgtgttttgt ttttagggat tgcgtttgta
    19381 taaaataaaa tcgggtcaac gacatgaata gaataagtgc catgtgcccg taagaataat
    19441 tctgcgttat agaaattgtc aaagtagttc aacggcgcgc ttgtaccgaa tttgattccc
    19501 tttatttctt ggagattgat ataaaaaact tgttgtttct gcggtgtgac gccgccaaat
    19561 ttgaatcggt caaaagtttc agcaattgct tctttcagtg ttccattgaa catggaagga
    19621 gctgcgtcat ttttaatggt gtaataacct tcctcagcgg tataatcgat gatttttcca
    19681 ccatcgacca aaagcatcat catgtttgga cagacatgga cgactgttcc gtctgttaaa
    19741 acatcttctg ttcctttacg attggagcca cgtttgtcat ctttgcggac tttgacacct
    19801 tttgtcatga ccgttgtatc actcatattg tctggttcga tgacttctag ccattgatct
    19861 gccagaccgc cgccaaccat acttgttgct gctttgataa gacccataaa aaattcctcc
    19921 tctgattcag ctagtgccaa acaattattg tttatttatt ataccatagg aagatgtgaa
    19981 acttctcgga ctagagacgg aattgaaatg gaaaattgcg tattgtttaa atacctgaaa
    20041 aagccgagaa ggatagtagt ttttttacct aatatcacgt ataataagag atagtgaatt
    20101 ttttaaaaaa gggggatcct tatggcatat caagcacttt atcgagtctg gcgttcgcag
    20161 cgtttcgaag acatcgttgg acaaaaagct gtgacacaga cactaaaaaa tgctattgtt
    20221 tcccacaaaa cctcacatgc ctacttgttt acaggaccca gaggaaccgg aaagacgagt
    20281 gcagcaaaga ttttcgcaaa agcaatcaac tgtccgaaca gtaaagacgg tgagccatgc
    20341 aacgaatgcg aaatgtgtcg atcaattact gctggtacgc aagaagatgt gatcgaaatc
    20401 gatgctgcca gcaataacgg agtcgaagaa atccgattta tccgtgatcg ggcaaattat
    20461 gcgcctacaa aggcagcgta caaagtgtac attattgatg aggtacatat gctttcaaca
    20521 ggagctttca atgccttgtt gaaaacattg gaagagccaa aagaaagtgt catattcatc
    20581 ttagcaacga ccgaacctca caaaatacca gctacgatca tttcacggac tcagcgattt
    20641 gattttaaac ggatcaatac ggcagatatt gtcgaacatc ttgaatttat cttgaaagaa
    20701 tcgactatca gctatgaacc agctgcattg aatgtgattg cccgttctgc agaaggcggg
    20761 atgcgggatg cattgagtat tcttgatcag gcaatctcgt ttagtgaagg aacaattact
    20821 ttagatgatg ccatgcaagt gacaggtagc ttaactgacg aaatgatgga cagttacttg
    20881 agtgcttgcg tgaaaaaaga agtaccagaa gcattggaaa cattgaacca aattctcgca
    20941 gccggcaaag aatcacgtcg ctttctagag gatatgttac aatactgccg tgacttgctg
    21001 atgtatcagc aagcacctaa cctagttgag gaacaatcga gtacgatcag aagtacattt
    21061 acagaattgg cacaaactgt ttcagcggat cagctgtttt caatgataaa gattttgagc
    21121 gatactcaaa atgaaattcg ttttaccaat agtgccgcta tttatttgga agtcgctaca
    21181 gtcaaacttg cacagctacc gtctgcttct gttccttcag cagatgtagc atttgcagat
    21241 gatcagatag taaaacagct acaacaagag attaaggaac taagaaacga aatcaaggaa
    21301 ctacgcagta atacaggaat tgagaataca aaagtacagc cggtacagca aacaaatcat
    21361 aaaaaacaga caagtaccta tcgtgtaccg acggaacgag tatataaagt tctgcgggaa
    21421 gcgacaagac agcatctgaa ccaagtaaaa gaagtatggg aagacttgct gatgagtcta
    21481 tctgtcactc agcgagcaat gcttaaagca agcgaaccag ttgcagctgg acctacagga
    21541 ctagtgattg cgtttgatta tgagattgtt tgtcaaagag cagcaaatga cgaagaattg
    21601 cagctttcgg tacacaacaa cttaagccga atgatcaaag attatgcgcc tgatcctgtt
    21661 tatattacaa gagaaagctg gccagaactt cgaagaaatt atttgacgca ggcacaagaa
    21721 gagggaacag aaaactcttt tgcttctgaa gactcagaag gagaaatcga gttgcttcct
    21781 caagaacaag aagtaccaga agaaacactt gtagtaaaag cagaggaact gtttggctcc
    21841 gaagctgtta cagtggtaga tgattaataa aaaggagtag ataattatga tgcgtggaat
    21901 gggcaatatg caaggcatga tgaaacaagt acaaaaaatg caaaaagaaa tggcagaagc
    21961 acaagagctg ctaaataaaa cagagtttac aggtaaagcc accaatgaat tggtcaaagc
    22021 ggtttttaca ggcgatcgtc gcatgaaaga tatccaaatc aatgaagaag tcgttgatcc
    22081 tgatgatatc gagatgcttc aggatcttgt cgtaatggca gtcaatgatg cgatcgcaca
    22141 aattgatgtg gaaactgaga aaaaattagg gaaatacgca aaaggtttgc caggatttta
    22201 gttttaaact gaaggagtaa tgaatatgca atatccagaa ccaattgcga aactgatcga
    22261 cagctacatg aaacttccag gaatcggtca gaaaacagcg acaagactcg ccttttatac
    22321 gatcgatatg aaagatgaag tagtaaatga atttgctaaa tctttgttaa gtgtaaaacg
    22381 cgatttgcat ttttgtagta tctgcggaaa catcacagaa gaagatccct gcgaaatatg
    22441 tagaaatcct tcacgtgatc gaagcgttat cctagtggtc gaagagccga aagatgtaat
    22501 ggcaatggaa aaaatgcgag aatatcacgg actttatcat gttctccatg gtgtgttatc
    22561 accgatggaa gggacaggtc cagaagacat caatatttct tctctgttgc agcggctgca
    22621 tgatgcagat gtaaaagaag tgattatcgc aacaaatgca acaacagagg gagaagcaac
    22681 agctatgtat ctctcacgtc tgatcaaacc cgcaggtatc aaagtgactc gtctagcaca
    22741 tggtctgtct gtaggctctg atatcgagta tgcagatgaa gttactttat tgaaagctgt
    22801 cgaaggaaga cgtgagttat aaatttctaa ttaagtgttt tttcagatac aatataaaag
    22861 cagcacaaga gatgggggca acaatgtgaa cggactattt attacaatcg aggggcctga
    22921 tggtgcagga aaaaccagca tcttgaatga actttaccct cttttgaaag aagtagcaaa
    22981 aacagaaatc attcaaacaa gagaaccagg aggcattccg attgctgaag agatccgagc
    23041 agtgatcctt gatccaaaaa atgatcggat ggatgaacgt acggaagcac tgctttatgc
    23101 agcagcaaga agacaacatc tagtcgaaaa ggttctgcct gctctggcaa aagggaaaat
    23161 cgttttatgc gatagatttg tcgacagttc tcttgcttat caaggtgcag gccgacgcat
    23221 cggcgttacc gagattgctc ggttgaatga gtttgctaca gaaggtacta cgccggattt
    23281 taccctttat cttgacgtag attcagacac cggattaaga agaatcaaga aaaacagaca
    23341 aaatcaaatc gaccgtttag attcggaagg tttggaattc caccagcgtg tacgtcatgc
    23401 ttacttaaag ctggcagaag agaatccgga aagaatccac aaagttgatg caagaaaaag
    23461 ctttgaagaa gtgctgcaaa caagttatca tacaattatt gaacagtatc cgcaattttt
    23521 tgaaaactag gaaggtgaac gtttatgaaa attattttag cgattatcca agacaaagac
    23581 agcaaccgtt tatcaaatga attgattgat gcaaatatcc gtgccacaaa actatcatcg
    23641 acaggcggct tccttaaggc tggaaacagt acgtttatcg tgggtattga agatgaccgt
    23701 gtagaagaag cattggaaat catcaaaaaa acgtgtgaat caagaaagca atttgtatct
    23761 acacctgtta cactggatat ttcgatggat gggggcgtcc cttatccagt agaagtagaa
    23821 gtaggcggtg ccacagtctt cgtcttacct gttgaaggat tccatcaatt ttaggaggag
    23881 ctgagctatg aatcaagaaa taaacttggc tcaaatgcaa ccgatcgtgt atcagcagct
    23941 tcaacggagt tttgagcatg ggcgtatcgc tcatgcttat ctttttgaag gggagaaagg
    24001 aacaggaaaa catgaagtag gtatatggct tgcacagcac ctgttctgta cccaaatgaa
    24061 agacaatctg ccttgtggaa aatgcaacaa ttgtcagcgg atcgaaaaga aagaacatcc
    24121 agatgttttg gttattgaac cggaaggaca aaccatcaaa gtcgatcaga tcagacgttt
    24181 gcagacggaa ttcagtcgca gcggttacga atcaagaaaa aaagtttttt tgatcaaaga
    24241 agctgaaaaa atgaatagca gtgcggcaaa cagtttgttg aaattcttgg aagagccccc
    24301 tggagatttt ttagcggtgt tagaaacaga tgcagtagga agaattctcc ctactattca
    24361 atctcgttgt caagttctgc attttcaaga actttcgaaa gaagcactga tccatcgatt
    24421 gcaagaagag cagattccat tggaaaaagc aaaacttttg gctttcttaa caaacagttt
    24481 aggaaaagca gttgaaatct ctcaagatga atggtttaat gatgctaagg acttgattta
    24541 tcaatggttc gtttacttgc aaaagcaaga tactcaagcc tttatctatg tccaaaaaaa
    24601 attggtaaaa tcatttaaag aaaaaacaca acagtttaca ggattatctg tcttgatgtt
    24661 ttattatcag gaagcacagc gtcaagcagt agcaaacggc gaatatggca aagtgaaaca
    24721 gataaaccag ataattgaac ggatattgat cgcagagcag aaactacgca gcaatgtcag
    24781 ttttcaggct gttgcggaac agttcgtttt gcatacgatt ttttagcttg ccgcaaagga
    24841 tgatgatcaa ggaggatgga aatggtagaa gtagtaggtg tccgatatag agatgcaggt
    24901 catatctatt attttgcacc aggagactct gaatatgttt atagtgacaa ggtattagtc
    24961 gaatctcagc aatccttaca tattgctact gttgtccttc ctaaaaaaga gattgatccc
    25021 aatgaccttc ctgaagctat ccgtccgatc ttgcataaag cgtcacaagc tgaattagaa
    25081 aaagacaaaa aaaacaaaaa agatgcttat gatgcattga aaatcgcaaa agaaaaagtg
    25141 cagttgcgtg agttggaaat gaaaatggtc aaagccgaat acacatttga tcgaaataaa
    25201 ttgatttttt ctttcacagc ggacgggcga attgacttta gagaattggt aaaagatctg
    25261 gccgctgtat ttcgtactcg tattgagctt cgacaaattg gtgtccgcga tgaagcaaag
    25321 ataataggcg gaattggtcc atgtgggcgt ccattatgct gttcttcttt tttaggcgat
    25381 ttcgtgcctg tatcaatcaa aatggcaaaa gatcaaagtt tatctttgaa tccaacaaaa
    25441 atttccggtt tatgcggacg cttgatgtgc tgtctgcaat atgagagcga agaatacgag
    25501 acagcgaaaa aagaactccc tgactttgga aaagtaattg ctacacctga tggtaaaggg
    25561 aaagtcgtag ggttgaatct gcttagccgt atcgttagta ttcggctgac tggacgggaa
    25621 aatcctgtcg aatatgaatg ggatgaattg aaagaattta tccaagtagg tgagatgaat
    25681 ggataagaga tcattatacg acggattgaa tcaattagaa tcagagttga gaaatacatt
    25741 aacagaactt gttgaaatga agcatgcttt gcatgagatc gtagaaaaaa atacaacttt
    25801 ggagatggaa aatcaacgtc tgcgggaaca cctgcgggaa ttgaaccaag ttgcacaagc
    25861 tccagctgaa aatgtgaagc aggaactttc taagtctcgt atgaatcttg aaaaaattta
    25921 tgaagaagga ttccatgtct gctacgattt atatggatca agaagggaca atgacgagcc
    25981 ttgtgcgttt tgtctagaag tgatctatcg cgaaagcggt cgatgaccaa taacaagagg
    26041 agactggagc ggagaaatac tgctccagtc tttttattaa ggagattgtg acagatgtat
    26101 aatcaaaaaa gtttcaaggg aaatccggta tatggggatt tatatcttgt accgacgcca
    26161 attggaaatt tagaagatat gagctacaga agtgttcgta tgctgcaaga atccgatctt
    26221 atcgcaagtg aggatacgcg taatacacaa aagttattga atcattttga aatccataca
    26281 ccccaaaaaa gtttacatga acataattat aaagaacgtg tccctcaatt gattgctttg
    26341 ttaaaagaag gaaaaacgat tgctcaagtc agtgacgcag gaatgccttc catcagcgat
    26401 cctggacatg agctagtttt agcctgcata aaagaaggga tttctgtgat ctctatccca
    26461 ggacctacag ctgggatgac ggctttgatt gcttcagggc tagtgcctca accattttta
    26521 ttttatggct tccttccacg taagaaaaaa gaacagaaag aaacattgaa aaagctaaaa
    26581 gaacagacag ttacgctgat tttttatgag tcaccttatc ggatcactgc tacattgacg
    26641 aatttcttag aaatttttgg aaatcgccaa gtcgttttgt gtcgggaatt gacaaaggtc
    26701 catgaagaat accttagagg aagtacggaa gagctactcg cttatatcga agaacatcca
    26761 gtaaagggtg aatgttgtct gcttgtagaa gggaatttgt tcgaaatgcc agtgacggaa
    26821 gttgatgaag agttgggaac gttaaaggaa caagtagaag caaagatcgc ttcaggcgaa
    26881 aaaccaaatg ctgctatcaa agcagtagcg ctgaaaaatg ggctgaaaaa acaagaagtc
    26941 taccgtcagt accatgaatt agactgagat agtataagtt gtctataatg aaagactaat
    27001 gaggaaatca gctactaact tttcaaatct cttgaacgcg aacgaatgtt cttgtataat
    27061 gaataagagg tgaggatgat ggagctgcaa tttcctttac ataatgatac atcaagaaaa
    27121 atcattcata ttgatatgga tgcttttttc gcttcggttg aagaacgaga tcatcctgag
    27181 tttcgcggac atccattagt aattgccaga caccccagtg acactggtgg gcgtggagta
    27241 gtgactacag caaattatga agcaagaaaa ttcggaattc attcagcaat gagtgcacaa
    27301 aaagcgtatg agctttgtcc gcaagccatc tttaagcctg gcgaccatca taaatacagc
    27361 gatatttcca aacaagtacg ggaagtattc tatcgttata cagatattgt ggaaccagtt
    27421 agtatcgatg aagcgtatct tgatgtgacc gaaaataaaa tcaattgcaa gtcagccatc
    27481 aaaatcgccc gaatgatcca agcagatatt tgggagagtg tccagctaac atgttctgcg
    27541 ggagtaagtt acaataagtt tttggccaaa ttagcatcag actatcaaaa acctagagga
    27601 atcacggtag ttgcccctca agacgctgtg ccatttttaa aagctttgcc aattgaaaaa
    27661 tttcatgggg tagggaagaa aactgtacct agaatgcatg agctagggat ttatacagga
    27721 aaagacctat atgaatgcac agaaatgatg ttgattcgaa attttggaaa aatgggctat
    27781 tctctttatc gtaaagtcag aggaatccat gattctccag taaacgttac aagagagcga
    27841 aaatctgtgg gaaaagagca tacttatggg cagccgttgc aaacggaaga agcagtgctg
    27901 actcagttgc gccaactagc tgaaaaagta gaagaagcac tgagaagagt ccaaaaacat
    27961 gggaaaacag tagttttgaa ggtcaggtac acggactatt ctactgtgac caaaagagtg
    28021 acattgccag aatatatcta taaaaaagaa gcactctttt atcaagcaag ccttatatgg
    28081 gaggaaatct tgggagtaga aaaaggaatc cgattgttag ggattacttt gacgaatctg
    28141 gacccgatga cttatgaaaa catcgtcctt ccattatggg aaaatcaaga aatataaaaa
    28201 cagctttgag agttgaaacc ggaaatccgt tttctctccc aaagctgttt ttatatcaag
    28261 tcttgctttt tgatttgttc ataggtttct gttgcatccg tacatttttc ccaaatcaca
    28321 acttgattgg attctaaaga tttttggacg tcaatgatcc gctggttgct acttccgcga
    28381 aattgtagtt ttaggtcacg tttgcttaat tcaaagcgtc cgtcaacaag gatatcgatt
    28441 tgcgaaagga gttctaattt atcttctgaa tcttgtagca attcatcaaa ggtatagcct
    28501 gtccatgacc agatatcttt tgtcgtaccg aactcttttc ggatacgtcg tacgacttgc
    28561 agacaaacat ctgtattcaa aaaaggttcg ccaccaagta aagttaatcc ttgcacgtaa
    28621 tcgttgcgca agtcagcgat gatttgttct tctaattcag gtgtgaatgg tttgccatat
    28681 cggaaatttt gtgcagcttt gttgaagcag ccttcgcagg caaataagca gccactaacg
    28741 taaagactgt tgcggacacc ttcaccatcg acaaaattaa acggtttgta gtcagcaata
    28801 tagttttggc tgtagtcttt tgctaaccat tcttttggtt ttggatttct cataaaaaaa
    28861 cttctttcat ttaaggttca aagatatagc tattgaagat aaaatctact cgaccacata
    28921 aataagaaca aactgaccta aatccattgt tcaagaaagc ttgttcttat tttgatagag
    28981 ggcgttcaaa gatacaaagc catcgaaaga gggtggtgaa aaaagacttg tcatagcctc
    29041 ttattctgaa taaacggtgt tcaaaagctt gcatctgcag taataagccc aactaaacga
    29101 aaaatatgag gaactatttt tgtttagcta ttcttattac ttgatgcagg acagcttttt
    29161 cacaacctca tttcatgtgt ttcacacgtg aggaaatttc tttatggcgg ccatgtacca
    29221 tcggacgagc ttgcggattt cctaaatagc cacaagtacg tttgactaca tcacatgttt
    29281 ttggatcatg atttccacat tctggacatt cgaaccctcg ttctgtcggt ttgaaatcac
    29341 cttcgaaacc acattgatag caatgatcga ttggcgtatt cgtaccaaga tacccgattt
    29401 tgtcatatgc aaaatcccat acagcttcta aagctttcgg attttgttgg agcatagggt
    29461 attcacagta gtggatgaat ccacctgaac aatattttgg ataatccttc tcaaattcca
    29521 atttttcaaa tggcgttggg tttttacgca catcatagtg gaaactgttt gtataatatt
    29581 ctttatctgt gatattttcg atgatgccga atttttctgt atccaaacgg cagaaacggt
    29641 cagttagact ttcacttgga gttgaataga cactgaaatg ataaccatat tcatcccccc
    29701 atgcatctgc attagctttt aattctttga cgatatcaag tgtgaaagct tttgcttctg
    29761 ggtttgtttc ccattcgcca ccgaagaaag ctgaagcaac ttcatacaat ccaatgtagc
    29821 ctaacgatac agtagctcga cggtttttga ataattcatt gacagaatcg gtacgtgaaa
    29881 gacgtttccc gaaagcacca tacatatata aaattggcgc atttgctgga atggcttctt
    29941 tacaacgttc tacacgatag agaagcgcat ctttcatgat ttctaagcgg tcagacagta
    30001 actgccagaa tttattctga tctccttttg attcgatcgc gattcttggc aaattcaatg
    30061 taacaacacc taaattcatt cgtccgacat ttacttcttg accattttcg tctttccacc
    30121 cttgcaagaa tgaacgacag cccataggta ctttgaaact tccagttaat tcaacgattt
    30181 tatcgtaatt cagaatatca ggatacattc ttttcgttgc acattccaat gctagttgtt
    30241 tgatgtcgta attaggatct tcagggttta agttcacacc ttttttcaaa gtgaagatca
    30301 gtttagggaa gatagctgtc cgcttttcac tccctaatcc attgattcga atctgtaaaa
    30361 ttgctttttg aatttctctt tcaaaccagt tttctcctag tccaaatcct aatgaagtga
    30421 aaggagtttg tccatttgaa gtaaataagg tattgatttc atattccaaa ctttgcatag
    30481 catcgaagat atcttttttg gtttttgctt ttgcatattc tttttggcgt tctggcgaat
    30541 cgatccattc ttccgcgtct tttagatgtt ttttatagtt caattctgca aaaggagcaa
    30601 gcaattcatc tgttcggtcg gcagaacagc caccatattg acttgacgct acattggcaa
    30661 taatctgtga gatttgtgct gtggcggtct ggatagattt tggcgattcg acttcggcat
    30721 tgccgatttt gaacccattg ttcagcatgc ctttgaaatc aatcaagcag caattcgtca
    30781 tcggtgtata aggatgataa tccaaatcat ggtaatggat atcgcctttt tgatgcgcat
    30841 ttgctatatg tggtggcaac attttcagtc cgattgattt tccaacgatc ccggctgtca
    30901 gatctcgctg tgtattgaaa acattactgt ctttatttgc gttttcgttc acgacagttt
    30961 ggtccttgtt gattagcttt tcaatcgaaa agttgatatc tgttgcttta ctgcgagcaa
    31021 aatctcgttt ggtacgataa ttgatgtact cttctgctaa ttcatattcg tttttttcta
    31081 gtaatatatg ttccgcgatg ttttgaatct catagatttt gacattttca gcaaaccggc
    31141 ttttgatttc ttggacaacc aagtctgcaa tcatttgaat tttttcataa gtaagtggtg
    31201 ataatgagcc gtgaattttc ttttctgctt tgatcagtgc ttcattgatc ttttgttcat
    31261 cgaaatcaac atggcggcca tcgcgtttga tgactttcat ctgggatgtc tctggctgct
    31321 gagtaacgac agttttttct tcataattta ctttcattat cttcaactcc tgctaaattg
    31381 ttcttgtcta tcataaaaca aaatcgggga aggagcaact aaatatcggc tatatatagt
    31441 attcaatgtg ctgtataatt ggatttctat actatatgta gtgtatattt tattgtgaaa
    31501 aaaggtgaaa acttgtagct ggtggatttg ttttttgcat atttaatttt gctgaataaa
    31561 ataattgaat aaaatttttt attcagtcca agtaaaagtg acaaaaacat aagagcaaat
    31621 tattcgtaga tatgctacta tgcaaataaa tagaaatgaa aaatgaaaga ggaggagaag
    31681 aattggaaaa gatgatcgaa gtgaaacatc taagtaaaag ctacggcagc aaactttctc
    31741 ccgtcaaagc cttagataat atctcattca cagtagaaga aggcgagttt gttgggatta
    31801 tgggcccaag tggtgcagga aagacaacgc tgatgaatat cttgtccacg atcaatttgc
    31861 ctacgatggg cagtgtctcg atccaaggaa aagaaatcac aaaaatgaaa aacagtgagc
    31921 tcagtgactt tcgtcgaaaa aaactaggat tcatttttca agagttcaat ttgatcgata
    31981 ccctaaatgc aaaagacaat atcctattgc ccctagcagt tgaacggatg actaaagagg
    32041 aaatggaaaa gagagtaaga catgtagctc aattgttgaa tatagaagaa ctgctcaaac
    32101 ggtatcccga tgaactttct gtcggacaga gacaacgaat tgcagctgct agagcacttg
    32161 ttgttcagcc acaagtgatt tttgcagatg aaccaactgg ctctttggac tcgaagtcgg
    32221 ctacagaatt gttgaactac ttgaagacca tgaatcaaaa agaaaaagca acgatactgt
    32281 tagtcaccca tgatccatat acagcaagct actgcgatag aattttattt attaaagatg
    32341 gtgtgatttt ttctgaagtt gtcagaagag ggacaagaag agagttcttt gagaaagtaa
    32401 tagacatgca ggcgacgatt ggcggaggag gaaaaatgaa tgctgtataa actagccgtt
    32461 aaaagttttt ttcggcagtc acgaggctat cttgtttatt ttttcagttt gactttatcc
    32521 gtaatgatct attattcctt cagcgcaatg acctacgatc aatctttagt cagaagagca
    32581 agtcaagata cttcgataga tggtggattg agttttggtg gatttatcat tactgttgtt
    32641 ttgctttttt tcgtattcag tgccaaccga tttttcttga atagaaggca aaaggaaata
    32701 ggcatctatc agctttttgg tatgaataaa ctgcagatat caggtatata tgtgttagaa
    32761 atcatgataa ttggattgtt cgcctgtatt tctgggatat tactcggtat tattttttcc
    32821 aaactctttt caatgatttt ggttcgaatg atggatatgg atcttactag tccatttttt
    32881 atctccattc catcagtagt agatacttta tttgcttttt tcatcatcct tttagcagta
    32941 tctgtatatt caatatggaa aatatggcgc tatccaatga ttcgaagttt tggagaaaaa
    33001 gaacaagcag atagttcaac aatgcgcttc aggacaaggc accgattact cgcagtcatc
    33061 gggttactac ttttaacgag cggatatttt ggagctagtc attttaggga aatcacttca
    33121 tggatgatca gttatcatta tcttgataca ttagttttct tttttccttt tttaattttt
    33181 ttcgtttgtg tggtcggtac ttatttgttt ttctgttata catttcggtt atttttgatc
    33241 atattgagta aatggaagat ttattactat ggtatcaatt ttttgataat gggtaacacg
    33301 caagttcatt tgctcaaaag ttggcgtaca aattctctga ttacagtcat tctcggaatt
    33361 tctttaatga caattggcgg cacggctagt atctctacta ttttatccta ccaggagaaa
    33421 gtttcctccc cgatggacta tcagtttgat gttgagacag agaaaaaaat caagccgatt
    33481 ctagcagagg aagggcagaa gataactaaa gaaatcacct tgcattataa agtcattggg
    33541 agtatctata gtcaaaatct cgaagaacct atgtttcaaa ctgctaatct gatcacggaa
    33601 acacaatatc aagccttcag aaaagttaat ccagatttgc cgaacatttc tttgaaatca
    33661 cctggtcata ctgttttgct tgatcaaatg caaactcttt ttcggaatat ttcattatat
    33721 ggatctagta ttggactgcc agataatcaa gaattgaaga ttcaacaaat gcttccaagt
    33781 gtattaggtg acgaaacaat ggtatatcta agtcctgtac tgattgtaga tgataccgtt
    33841 tttgaaaaag caaaaggtgt ggattatcaa gtagtcaatg tagatgtatc aggtggaaat
    33901 aatgaaaaaa tagatgaacg actgagcaat gacctgtcga taaagtggct caatgctgtt
    33961 tattattctt atgatatcgt aaatggaagt ctacaaggag aaattagcac aaagaaactt
    34021 ccggatgacc aaatgaagga agcacaattt agccaagaaa gctctcgttt gaatttctct
    34081 tccagctatt cgaaattgcg tgcagttaat cggcgaatcg gtatcaatat ttttgtcaca
    34141 ctatttgtcg ggatgatcgt gattattgct actggtagta ttttgacagt ccggcaatta
    34201 gcagaagcag aggaagaaaa agaaaattat cacctattga ctaagctggg gattccacaa
    34261 agaaggatca gacggatgat cttcgagcaa aacgcactta ccttctttcc acccatgata
    34321 ttagggatca ctcacgcagt atttgcaatc aatgtcttca ctcagtatat aaaaactgcc
    34381 gattactggt tggcttatct tgtgagtggc ttattgatcc ttatctatct tttgctttat
    34441 gtcattacga gtcagttata ttgtcggatt atcgaggaat gatatacgga ataagacaag
    34501 ataataaata gaactaaatt ttgaatacca tttatttgga ataagaggtt gtgacacgat
    34561 ttttgtcaca acctctttat ttttt
//
LOCUS       DADVXM010000023        31169 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.024, whole genome shotgun sequence.
ACCESSION   DADVXM010000023 DADVXM010000000
VERSION     DADVXM010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31169
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.024"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            147..1016
                     /locus_tag="KB927_001175"
     CDS             147..1016
                     /locus_tag="KB927_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBB6840108.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1225..2250
                     /locus_tag="KB927_001176"
     CDS             1225..2250
                     /locus_tag="KB927_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBB6840109.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2289..3239
                     /gene="manA"
                     /locus_tag="KB927_001177"
     CDS             2289..3239
                     /gene="manA"
                     /locus_tag="KB927_001177"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBB6840110.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3333..5036
                     /locus_tag="KB927_001178"
     CDS             3333..5036
                     /locus_tag="KB927_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6840111.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5038..7071
                     /locus_tag="KB927_001179"
     CDS             5038..7071
                     /locus_tag="KB927_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6840112.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7082..7522
                     /locus_tag="KB927_001180"
     CDS             7082..7522
                     /locus_tag="KB927_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6840113.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7722..8849)
                     /locus_tag="KB927_001181"
     CDS             complement(7722..8849)
                     /locus_tag="KB927_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6840114.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8852..9529)
                     /locus_tag="KB927_001182"
     CDS             complement(8852..9529)
                     /locus_tag="KB927_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840115.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9793..11559
                     /locus_tag="KB927_001183"
     CDS             9793..11559
                     /locus_tag="KB927_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBB6840116.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11574..12011
                     /locus_tag="KB927_001184"
     CDS             11574..12011
                     /locus_tag="KB927_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6840117.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12024..13175
                     /locus_tag="KB927_001185"
     CDS             12024..13175
                     /locus_tag="KB927_001185"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBB6840118.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAEFIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13237..13935)
                     /locus_tag="KB927_001186"
     CDS             complement(13237..13935)
                     /locus_tag="KB927_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBB6840119.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(13928..15280)
                     /locus_tag="KB927_001187"
     CDS             complement(13928..15280)
                     /locus_tag="KB927_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBB6840120.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15503..16903)
                     /locus_tag="KB927_001188"
     CDS             complement(15503..16903)
                     /locus_tag="KB927_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBB6840121.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17064..17801
                     /locus_tag="KB927_001189"
     CDS             17064..17801
                     /locus_tag="KB927_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBB6840122.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            17926..18405
                     /locus_tag="KB927_001190"
     CDS             17926..18405
                     /locus_tag="KB927_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBB6840123.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18402..19169
                     /locus_tag="KB927_001191"
     CDS             18402..19169
                     /locus_tag="KB927_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840124.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19399..19968
                     /gene="lepB"
                     /locus_tag="KB927_001192"
     CDS             19399..19968
                     /gene="lepB"
                     /locus_tag="KB927_001192"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6840125.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20072..20674)
                     /locus_tag="KB927_001193"
     CDS             complement(20072..20674)
                     /locus_tag="KB927_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6840126.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20780..21249
                     /locus_tag="KB927_001194"
                     /pseudo
     CDS             20780..21249
                     /locus_tag="KB927_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21355..21939
                     /locus_tag="KB927_001195"
     CDS             21355..21939
                     /locus_tag="KB927_001195"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBB6840127.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            21942..23015
                     /gene="prfA"
                     /locus_tag="KB927_001196"
     CDS             21942..23015
                     /gene="prfA"
                     /locus_tag="KB927_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBB6840128.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23008..23847
                     /gene="prmC"
                     /locus_tag="KB927_001197"
     CDS             23008..23847
                     /gene="prmC"
                     /locus_tag="KB927_001197"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBB6840129.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23840..24019
                     /locus_tag="KB927_001198"
     CDS             23840..24019
                     /locus_tag="KB927_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840130.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24041..25066
                     /locus_tag="KB927_001199"
     CDS             24041..25066
                     /locus_tag="KB927_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBB6840131.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25241..26485
                     /locus_tag="KB927_001200"
     CDS             25241..26485
                     /locus_tag="KB927_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBB6840132.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26638..27585
                     /locus_tag="KB927_001201"
     CDS             26638..27585
                     /locus_tag="KB927_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6840133.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27719..28348
                     /gene="upp"
                     /locus_tag="KB927_001202"
     CDS             27719..28348
                     /gene="upp"
                     /locus_tag="KB927_001202"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBB6840134.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28487..28729)
                     /locus_tag="KB927_001203"
     CDS             complement(28487..28729)
                     /locus_tag="KB927_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840135.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            28850..28922
                     /locus_tag="KB927_001204"
     tRNA            28850..28922
                     /locus_tag="KB927_001204"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28883..28885,aa:Thr,seq:cgt)
     gene            complement(29041..29679)
                     /locus_tag="KB927_001205"
     CDS             complement(29041..29679)
                     /locus_tag="KB927_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6840136.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29802..30434)
                     /locus_tag="KB927_001206"
     CDS             complement(29802..30434)
                     /locus_tag="KB927_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBB6840137.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30785..31084
                     /locus_tag="KB927_001207"
     CDS             30785..31084
                     /locus_tag="KB927_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBB6840138.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        10634 a         5445 c         6284 g         8806 t
ORIGIN      
        1 tttataagag tttttactca ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca
       61 ttttttttaa caaaatcaaa gttattgctt gaaagaagaa gaatccatcg ttaaaataaa
      121 gcttgacgta gaggggagca agaaatatga aagattttca attgggggct gccacctatt
      181 taaaaagtgt agccattcgg gtgaaagacc gagataaaat gattgatttt tacaagaacg
      241 ttgttggctt tgatttgaaa agagaagaaa acgaattagc cattttagga acagaagaag
      301 ctggaagtga aatgttgctg ctggaagaaa gtcctagagc gaatgatcac atgggggtga
      361 tcaaaaagct gaaccgtttt tcattgatta tccctagcac agaagaaatg gcagatatcc
      421 tttgtcgtat ccgtaaaatg aattatccaa tcaaagaagc tttagaagat catggacgta
      481 tggggatttt gctcgtagac ccagaagaga atgaattgga aatttaccat gaagagaata
      541 agaacgacca aagagaaatt ccagaaacaa tggatcaaga agcattatta agaaaatctg
      601 aagaaaaatt cagtaaacta tcaacaggtt cttattttga aaaaatccat ttaaatgtta
      661 ctaacttaac aaaagaacgc caatttctta atcatgtact tggtttgaag gtacataatg
      721 aagaagaggg catccatgta ttgaatgaag gagatttcca tgttggtttg acagaagcta
      781 gcggaggcgc aattgatttg cctacagatg aagtgattgg acttgatttt ctgaaattca
      841 tgatcgatac tgaaagcatg gaaggactga ttgctcactt gcagcaacta tcagttgatt
      901 tcttcttaga caaaaagcac acagtactca caatctatga tgctatagga atcgaatggt
      961 ggttcgtcag tgagccaaaa gaaaagaata aaactgacat tcgatgcgac gcttaacttt
     1021 ttctttctta acgattgtcg catgtctcgt cattttatga acggtcatac tatcgcttat
     1081 tctagagata gaaagagaaa atagtatacc gggggaaact gcgcggtttt tcgcgcagtt
     1141 tttttgtgta aaaaaggttg attcctcata gattaagctt taagcttgga ctgtaagaat
     1201 ctgatagaaa agcaggagaa aaagatgtat ccacacacga aacagcttat tttgaaaaag
     1261 atggaagaag gattttatcc aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa
     1321 acatttacag ccggctttgc ccaagtcgtt cctgaaaagc agctgatgac agaagatctg
     1381 ttgtttgatg cagcctcact gacgaaagtc gttgcaacca cttcattagt tttacgtcta
     1441 ttagaagatg gaaagataga actcgatcaa ccgcttcata aatatcttcc tgaatttgaa
     1501 aatcagacaa tcactttgcg tcatttactg acacatactt ctgatatcaa aacatggata
     1561 ccaaacagag ataagctatc tcaggaagaa ttgatcgccg cttatttgaa gctagaacca
     1621 ggtgagcaac taggaaaaga agtaaaatat acagatgccg gtacgattct tcttgggttg
     1681 atgctagagg aaatttacca agaaactgca gtggaaatct ttcaagaaca agtattggaa
     1741 ccattaggaa tgatgaacag cttatttctt ccttttcctt ccaaaaaaat cgttcccaca
     1801 gaacaactgc cttcgggtga ggttttgcgt ggacaaactc atgatccgaa agcaagagtt
     1861 ttggctgaac atgcaggtaa cgcgggtctc tttattgatt tgaaagacag cattactttt
     1921 gtccaaatgt atttgaacaa gggaaaaatc cgtaatggtc gttttttaga agaagagacg
     1981 attgattctt tactgcaaga tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg
     2041 gacttaaaaa aggatgtaga agacggtcat gcgattcttt ttcatactgg ttatacaggt
     2101 acgtttttct tgattgatat aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta
     2161 catcctgtcg atcatcgtgc ggagtatctc atatgtcgag atgaaattgt tgaaaacttt
     2221 ttgaaagaga aagcggtatt accgaaataa tgctataata gctatgaaaa atgagaggag
     2281 tttgaattat gcaggaacct atgtttttaa aaccagtttt tcaagaaaaa atttggggag
     2341 gaagtcgttt acgttcagtc tttggttttg atatccctaa cgataaaatc ggagaagatt
     2401 gggcgatcag tgcgcatcct catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga
     2461 aaagattaga tgaactatgg tcagaacaca aggaattgtt tggccatcct tcagaaccag
     2521 tgtttccatt attgatcaag atcttagacg cagaagatga tctatctgta caagtacatc
     2581 cagatgatgc ctatgggatg aaacatgaag gtgaattagg aaaaactgaa tgctggtata
     2641 tcatcgatgc tgaacctggt gcagaaatca tctatggtca tcatgcaaag acaagagaag
     2701 aactagctga gatgatcaaa gatgggcgct gggatgacct tttgaagaaa gtaccagtta
     2761 aaaaaggtga tttcttttat gtaccaagcg gaacgatcca tgctattggt aaaggaatca
     2821 tgattttaga aacacagcaa agttctgaca cgacttaccg cgtgtatgac tacgacagaa
     2881 aagatgcgca aggacaaaca agagagctgc atatccaaca atcgatcgat gtaacaactg
     2941 tccctgcgaa aacaccagaa ttacaaatca aagaagtccg aaaagggaat tcatcgatcg
     3001 tcacttattt agaaactgag tttttcaatg tatatgagtg ggatattaaa ggaatcacat
     3061 ctttcaaaaa acaagcccct tatacattga tgacggtaat cgaaggagca ggagaccttg
     3121 tcgttgacgg aaaaacatat ccattagaaa aaggaacaag ctgtattatt ccaaatggcg
     3181 tttctgagtg ggcggtccaa ggtgaactag caatcattgc gtctgaacca ggcaaatagt
     3241 tcccagatag ctgaaagcag cagacggttt ttcgtttgct gctttttcta cataaaatcc
     3301 gtccatcaat aaatagaagt ctggtgaaaa agatggaata caaatggaaa gcaaacaaca
     3361 gcagtcgcgt gtctatgaaa caactgagaa aagctggaca tcacttaaat gaaatgatca
     3421 tgccaaatct aagtctgttt atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt
     3481 ctggcgattt gcacaccaca ttagaagagg tatgccattg gatgatccag ctgcttttac
     3541 ccatcttgat cagttattca ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg
     3601 gtgcaattgc ttctttaggg ttgatcgctc gttccaatgc tccacaaatc gtaggagcga
     3661 tgattatcgg gccgcttgcc ggcatcgtat atgaacaatt tgtttctaga ttccatgtga
     3721 aattcaaggc tggatatgaa atgcttgtca gcaacctact agtaggactg actggtagcg
     3781 ttatttgtat aattggaatc gtttttattg aaccagtttt aaatagtgtt cacttgttgc
     3841 tcgcctccgt tgtgtcttgg ctagtcacaa tgaatctgtt accacttgtc agtctgatct
     3901 tagaacctct aaaagtacta tttttcaata atgcaatcaa tcatggtgta ttgacacctt
     3961 taggaatcga attctcacaa acagtcgggt actcttcctt atttttgatg gaggcaaatc
     4021 ctggacctgg tttagggatc ttactttcta tcctttgttt tgcagaaaaa caggaaaaag
     4081 taaatgcgag tggagcattg atgatccatg cgattggcgg gattcacgaa atctattttc
     4141 catttgtctt gctgcgaccg tatctatttt tagctgtaat ggctggtggg gcaagcggca
     4201 cgttgatatt tcaatggtta gatacgggat tagctgcacc tgtatcgcct gggtcactac
     4261 tcgtgatttt tgccaatgcg ccttatccac aactagctgg ggtaagtata gggatagcaa
     4321 tcagtacatt tgtgaccttc atttgtgcag cgatactatt gaaattacca aataaagaaa
     4381 aagagaacaa aacggtcaaa gaaaggggag aaatcttgga accatctatc attcattccg
     4441 tcatttttgc ttgcgactca ggtatgggat caagtgctat gggagccgcc ctgctgaaaa
     4501 agaaattagc agcagaaaaa atcgatcttt ctgtcggata cagctctatc tatgaattga
     4561 ataaccaagt aaatcagctg gttatcgtgc aacatgaact agcgggtctt gcaagagaaa
     4621 aagtacctca aagtcaaatc tatgtactgg atcacttttt ggaaacagat atcttgctgt
     4681 cacgaataaa agaagcgatc caatttccaa agcgggaaga aaaaaaagag atagcagata
     4741 tcacagaaca aaaaacgtcg cctgctaata ttgtattttt gtataaaaac aacagacgcg
     4801 gctcacaaac tatgggcatg acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt
     4861 ttgttatctc aaaagaatca atagaaaaaa tcaaaatcca agaagaaacg atttatatcg
     4921 cacaaagaga actagctgta actgaacagc tagaagaaaa gatccctcgg ctagttctag
     4981 ttgaacattg ggtagctacg aatgaatacg aaaaactcgt gaagggagaa atataagatg
     5041 tatttatcgc ccagagaaaa acaattatta gcagaatttc tcagtagccc gtcacctgta
     5101 tctatccaaa aaatgatgaa tttattgaag gtcagtaaac ggactattta ccgcgaatta
     5161 gataatcttg aagtctcatt gaaatcggta aatgcttctt tgaaaaaagc agctagaggc
     5221 tcatttgtca ttgaggcatc agaagaagta ttagagcaat taaaagaaaa tacagatggg
     5281 aaaagtaatg acttatccac tgctaaacga caacacgcga ttttagccga gttgttactg
     5341 acgacagagc cgttgagtct tgctcatttc atggaatcat atcgcatcag taataccact
     5401 ttttatgcag atatcaaaca gttggaagaa agtattcgcc aactgccttt ggaaatcatt
     5461 cggaaccagg gatacgagat cgaaggaccg gaaaaatacc gccggcttct gacagcgaat
     5521 gtattagaat tagaaatcaa tgaatatgaa ctttttcata gtatttcttt cgatgcatca
     5581 ctgaattatt tttttcgatt cgttgatccg caacatctat ctcttgcacg caaagtaatc
     5641 ggggaagaat tgatccaaaa aaagaccaat ctaagtgata gaaagcttga acatttggtt
     5701 ttgatgctga cattgacgat ggagcgtgtg acgaaaaatc atttactgac aaatgagaca
     5761 tataatagtc tggcaaacaa agaattacta cagacagcta aacgattgtt ttcacggatc
     5821 gcttctgaga caaaacaact ttatccagta aatgagatcg tcttttttgc aggattatta
     5881 aatgacttca cgaactcatt tgatcagaat ttctttgaag agacgttcga tacacagctt
     5941 gcttatttag taaaacaact gattcaagaa gtaagtgaag agacgaatgt ccatttttat
     6001 gaagatgaaa ctttgtacaa aatgctgttg actcatttat ctggtgtgtt ttcaagagcc
     6061 gttttacaag aagagacact gaccaatccg attttagaaa aaatcatggt tcaatacgag
     6121 gaagttgcga atgcaatccg taaagcagta gagcggattt ttcaagaaaa aaaattatcc
     6181 gaagaagaga tcgcttatat ggtccttcat tttgcgaatt cattggaacg aagtccgaaa
     6241 gaaagcaata tcagtattgc aggattttcg ccaagtggat tagcttctac tagcatgttg
     6301 gaactacgat tgaaaaggta ttttcccttc atccaacaaa ttcatttcta tcggattgct
     6361 gatttaaaaa aaatcgattt acaagaagaa tatgatgttg ttatttctac atctatttta
     6421 ccaggatacg gtggaaaata tattttagtc tccccgctac tgctagaaga tgaagtcaag
     6481 cagctaaaag aagctttttc gcatattgag aagaaaaaaa ggcaaaaaat tacgtataac
     6541 agcaataacg agtggatgat agaagatact tatgaggaaa caatgcattt catggatcaa
     6601 atcaatcaat tactcggtcg tttttttatc caagaactgg ataatcctga gacgatttcc
     6661 gaaacgattc gcagcttatt tccttatttt cctgaaggac tagtaacgga tgaagaggtg
     6721 gttcatcgcc ggctgcttaa gcgatatgaa caagcaccta tcggtattcc tcatacaaat
     6781 atggggttat tccatacatc cagctcattg atttctaaac cgatcttttg tattttcaat
     6841 ttgaaacatc cgttgaccat tgaagggatg gatagacagc cagtcgattt gtcccgtatg
     6901 ttagttatgc tggcgccttc gccaatccaa gaaaaagacg ggattctttt aggaaagatc
     6961 agtggagcaa tcatcatgaa tgacttgaac accgagatct tccgctcagg aaataaagaa
     7021 atcgtttatc agttgttagc gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa
     7081 gatgatacag ctaccagcag aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga
     7141 agcgttgacc gagatcggcc agtggatgac ccaacaaggg ggaatcaaac cggcatatat
     7201 ccaatcaatg atcgaaagac aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt
     7261 gccacatggg actgacaaag atgaagaagt agtagaagaa ggaatctatt tagtccaagt
     7321 gcctgatggt gtggactttg gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt
     7381 agtggcttta aaaaaagaac atcagttagc ggtgctccaa gatttagcct ttttctgttc
     7441 agacatcgac caagtaatgg cgctcagtga tgcggaaacc attgaagaag tccaaatgat
     7501 ttttgaacat ggacatatat aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt
     7561 aataacttca accaagataa aaataagagg agctattttt gttgggaggt tcttattact
     7621 gcggatgcaa gcttttgaaa actatttatt ctagaaaacc gtttatttga aataggggac
     7681 ggtgacaagg tttttgtcac cgcccctatt atttttgtgt tttaatagct cttttttata
     7741 tagatagtgc ccatacctat gaataataaa acgatactcc atataccaag tgtcaagata
     7801 ccattcatga aagtaacctg ttctgaagct agtggcgaga aaatatctcc tcctatgatc
     7861 acattttgaa aatcaacata agaagttggc aagtaatgac tgattgattc tatccatcca
     7921 atcgaagaaa acaagcgata ctctgctaag aaaagacaaa gaagtgtacc taaaagattg
     7981 actagagaat gttcaaataa agcagataga agaaaactga ttgtacttaa aaagagcacc
     8041 cacaacaaca ggaacagaaa gctctggaaa agatactcat acatcggcag gattcgtatc
     8101 tcctgaccaa tgatcgttcc tacaggataa cggaagtctc ccaaaccatt tttgattatt
     8161 actagtatag agacgatcaa aaatggcatc acgagactta gcatagctgc accataataa
     8221 atggtaaaac ggatgctatg tttctttacc atactatccg gtaatagatt gactagagag
     8281 attacctgct ttcttttttc ataagagatg atggaagaaa gaaacaaggc ggttatacat
     8341 aaaatcaaaa aactagaaat cattcctgaa aaaatatttt cgtagtaatt tgctaaagag
     8401 agatgcgctg gcaagtcaaa aatagaatat ctttggatct gatgttcttt catataacgg
     8461 agcaactcga cacgtttttg ttgttcaatg attggaattc cttgtctttg accagaaatc
     8521 agtcgatcca gtatatcttt ttcataatga taagttgctt cgaccatttg ctggacattc
     8581 cctgtgtttt ttgcatgtaa gattgcttcg atcagtttgt tgcttttctc taaactttcc
     8641 acaaattctt tctcattctc atcttctttc aacgtttcaa tcaaacgttg catctcttca
     8701 tagttatgat tcagttcatc gaattctgta taagcaagtt tatgatcaaa aaaaagtggg
     8761 aatgcaaaga gcacgaccaa caatagagga aataaaaagt ttactttgtt ttttagtaag
     8821 agattgcgtt caaatgtaag taaagacata gttacacctc atataattta cgataaatag
     8881 ctaaaatctc ttccatattt gaggattctg tgacgatttc tccatttttt agaaaacatg
     8941 ctttagaaca aatcgattgg atattcgcga tagcgtggga agaaagaaga atcgtcttcc
     9001 cctctttctg ccattgtctg atgaggctat tcaagatatc aatacttcct gggtctaatc
     9061 cgttcaacgg ttcatcgaat aacatgacag atgaatcact gatcaagtaa gcagcaagca
     9121 agacatgttg tttcattcct agagacattt ttccaatcgg caaagtaagg tactcagtca
     9181 tcttcaatcg ttggaaaaca gtttggcatt ctactttgct ctgccaatag tatttgatca
     9241 aagtcaaata atcaacagcc gatagatagt cggataactg attcgttgat tctagaaaaa
     9301 agaaagaccg gcgataatct gtataagcag taggagagat gttgtgaagg gacaattgat
     9361 cataagttgt tggcagcagt tgggcaatgc cattcagcaa agttgttttg ccaaatccgt
     9421 tcggggcaat caaagcagct acttctcctg attctactaa aagattcaat tgtcgaatca
     9481 cacgtttttt accacgtttc atgttcatgt ttttgatcag taatgtcata gataggcctc
     9541 caatataaaa tttaataaca taatagaatg gaaaacatct aaattaaatg ctaacaaaag
     9601 ttattgtttg catattataa aaaaattaaa ataacagttt tatttaaaat tgaagttttc
     9661 tgataccgaa atctttttat tttgctgaca tactcaaacc tttggcacaa agtttcgtgc
     9721 caaagtacga ctatttctct ttttagtaag cggatacaat tagagtatca aaaggagaga
     9781 gggagagaca aaatggaacg gacgattccc aaaaacaaca tttcgctaaa agcgagggta
     9841 caaaaattag gcagtacttt atcaagcatg gtcatgccaa atattggagc actgattgcc
     9901 tggggtgtat taacggctct atttatccca gatggttatt taccaaatga ggctttcgct
     9961 accatggtaa gcccaatgct aacttatctg attcctttat tgatcggtta tactggcgga
    10021 aaagtaattg ctggtgaccg cggatcagtt gttggggcaa ttgcaacgat gggtgtgatt
    10081 gtcggaacag atattccaat gatgctaggc gcgatgatca tgggacctct tggtggatat
    10141 gccatcaaga aatttgatca gctattccaa aaacggatca aatccggttt tgaaatgcta
    10201 gtcaataatt tttcagcagg tcttatcggt tttggattag cgttattagg tttttctgcg
    10261 attggtccag ttgtcgatgc attgactcaa gcaatggcaa aaggtgtaga gatcatttta
    10321 tctgcccatt tgattccatt gacaagtatt tttattgaac cagcaaaaat cttatttttg
    10381 aataatgcaa tcaatcatgg gattttgaca ccattgggaa ctgaacaagt agcagaggct
    10441 ggaaaatcta ttctattctt gcttgaagca aatcctggtc caggacttgg cgtattactt
    10501 gcttttactt tgtttggcaa aggagcagca aaatcttcag caccaggagc catgatcatt
    10561 cactttttag gcgggatcca tgaaatctat tttccttacg ttatgatgaa accgttatta
    10621 ttcttatcag ttataggcgg aggaatgtca ggaagtttca ttttccaatt gatggatgct
    10681 ggactaagag cgccagcttc tccagggtcg atcattgcga ttctagcgat gacaccgttc
    10741 aattcttacc ttcctgttat tttgggcgtg attgttgccg cagctgtttc gtttggtatt
    10801 tctgcagtaa ttttgaaagc ggatgcgaaa gatacaaatg aagacttcga aaaatctgtt
    10861 caagagacaa aggcagctaa gcaagcttcc aaaggtgccc aaggtattcc tcaaggagct
    10921 acattctctg gcgtacaaaa aatcattttt gcttgtgatg caggaatggg atcaagtgcg
    10981 atgggcgctt cgatcttgag aaaaaaagta caggaagcag acttgcctca aacggtgacc
    11041 aatcaagcaa tcagccaact gacagatgac tcgaatacat tgatcgttac tcaggtcgaa
    11101 ctacaagaaa gagcaaaaca aaaagcaccg agcgcgcgtt ttgtctcagt agaaaacttt
    11161 ttgaattcac ctcgatatga tgaaatcatt caagaattaa gcagcaagca gaaaacatca
    11221 gtttctgaaa ttgagaatga gccagcagaa gagtttcttt cagcaaacat caaacaaatc
    11281 aaagagattc tacttgtcca cgatgatcgt tccggatcag caacaatggg gatgaccgtg
    11341 ctcaaagata tattagacaa gaaccattta actatcccgt taagaaaagt caatatccaa
    11401 gatttaaaag atgaacctga ttcactgatc gtagccaaag aaagtttagc ggaaaaagta
    11461 cagatggctg cacctcaatc cattcattta tcagtcaaca gcatggtcaa tccgcaaaaa
    11521 tacgaatcga ttgcacaata tttgaaacag acagcttaag ggaggaaaac agcatgcaaa
    11581 gtttgccatt cgacatgatc gagctcaatc gatcttttaa aaccaaagaa gaagcgatcc
    11641 gctattgcgg tcagatgctt gtagaagcag ggtgcgttga tgaggaatat atcgatgcca
    11701 tggtagatag agacaaaatg ttatctgttt atatggggaa ttttatcgcg attcctcatg
    11761 gaacagatga agcaaaaaaa tatgtgaaaa aatccggcat ctgtgtcgtt caagtaccag
    11821 atggtgtaga ttttggtacc gaagaagaag aaaagattgc gactgttttg ttcggtattg
    11881 caggagtcgg agatgagcat ttgcaacttg tacagcaaat cgcactttat tgcagtgata
    11941 tggacaatgt tgtccagcta gcagacgcgc tcagcaaaga agaagtaacg gaaaatctag
    12001 caattgctta aggagagaga aaaatgagag cagtacattt tggtgcagga aatatcggtc
    12061 gaggatttat tggagaggtt ttggcagcta atggatttga gattactttc gtagatgtga
    12121 atcacacgat cattgatgct ttaaatgaaa gaaaagaata cgaaatcgaa ttagcagatg
    12181 aatcaaaaga aaaaatcact gtaaaaaatg tcaaaggaat caacaatcaa acaaatccag
    12241 aaaaagtaat ccaagaaatc gctgaagcag atttagttac taccgccatt ggcccgaata
    12301 tcttaccttt tattgctgag tttattgcaa aaggtatcca agaaagagaa aaggaaggaa
    12361 gcacaacatc tttagatatc attgcctgtg aaaatatgat tggcggttca gcatttctag
    12421 aaaaagaagt gtataaatat cttccggaaa catcatttac tgacaaatat atcggctttc
    12481 caaatgcagc agtcgatcga atcgtcccat tacaacacca tgaagatcct ttattcgtcc
    12541 aagtggaacc tttcaaagaa tgggtcattg acgatagcca aagaaaaaat aaaaaaatcc
    12601 aattaaaagg ggttttatat gtagatgatc tagaaccata tatcgaacgc aaactattta
    12661 gtgtcaatac tggtcatgcg actgtcgctt atacaggtgc cttgttaggt taccagacca
    12721 ttgatgaagc aatgcaagat gcgttagttg tggcacaatt aaaatcagtt ttgcaggaaa
    12781 caggaagttt gctgattgcc aaatgggggt ttgatgcaga gcagcatcat gcgtatattg
    12841 aaaaaatcat tcatcgcttc caaaacaaaa atatctctga tgcgatcaca cgtgtcgctc
    12901 ggacaccatt acgtaagtta ggttatcaag aaagatttac acgtccagtg agagaactac
    12961 aagaacataa cttgacttgc ccacatttga cggcaacaat ggggattatt tttaattact
    13021 atgatcctga agatgaacaa agccgtcaat tgcatgaaat gaagatccat gaaaacttgg
    13081 aacaattgat tcaagaagtc acaggaatca atgatccgaa aacaatcggg aatatcaagc
    13141 aaaacgtgaa ccgttatgcc aagcaagtcg cttaaaatag gatacgaaaa aggggaatgt
    13201 gacgaaattt ttgtcacatt cccctttttc gaataactag gctgtttgtc cttcaagata
    13261 gggcagatcc aattctttac cgtaacgttg ttctaaagct aggcggatca aacgagctgc
    13321 caggttctca tttcttgcaa ggataggtcc atggaaataa gaaccgaaga catttcggta
    13381 aatgacacct tcagattggt cttcaccatt atttccttga ccttgtacca ctttccccaa
    13441 aggtcgttca ccttcaccta agaaagtccg accattgtgg ttttcaaatc cataataagt
    13501 ttcattgaat tcttcgttat ggataacgat atcaccgata aaccggttat tttcctgact
    13561 taacgtgtag tgatccagtg cactgattcc ttggatcttt tctccattag ctcccatgta
    13621 gtagtgacct agcaattggt agccaccaca aatggctaac atgacgccat cattttcgat
    13681 atagttgatc aaagaatctt tctttttctg gatgtctttt gaaatgatta attgctcaaa
    13741 gtcttgacca ccgccaaaga aaaccaagtc atatttatca gcatcaaaag gttcatgtat
    13801 actaacgatc tccgtatggc aagaaacccc cattttttct gctatatatt tcaacatcaa
    13861 aaggtttccg ttatcaccat atgtgttcat caaatttcca taaaggtggg cgatattgag
    13921 ttcataatta gccacggttc attcctcctt tgataaatcc ttgagcagct agttctttac
    13981 gaagctgcaa tacagcagtg taagtagcta aaatatagac atgctcagtt ggcaattctt
    14041 tgattttttc gattacttct ggtaattctt ttgtttctgt caatttattt tctggaatcc
    14101 cggcaacttt tagacgtaaa gtcatatctg tatgacggtc tcctccagaa ataacagctg
    14161 ggatatccat atcggcaaag ttttcaaaat taccatccca aatccagctg acatcgattc
    14221 cgtctgcgta attggcattt aataaagcca ctaaagaaaa tggataagga gctagaccaa
    14281 tcatatcgat tacttgattg atacctacag gatttttgac aagtactaat gtacattttt
    14341 tcccattgat attgatgact tcttgtcggc cgaatacttt ctcgtcatat cctaaacctt
    14401 gtttgatttt atcaggatcg acattgaagt actctgccac tgcagtagct gctaaagcat
    14461 tgtagacatt atacataccg ccaacttcga ttccgtattc atgaccatcg atcacgaaat
    14521 ctgctgacac attgtccatc cgtaccatat cagttaatcg ataatccaat tcaggacgtt
    14581 tgaagtcaca atttggacag taatatttcc ctaagtttgc ataagtgatc attttataat
    14641 gcaagatgtg atgacaattt ggacataaga caccgtctgt attgtaatga gccatttgtt
    14701 cacgatcttc ttcatggtca aagccataat attttctagg attgactgtt tcgatagaat
    14761 tgaagattgg tgaatcaccg ttactgataa tcgttgcatt tggtgacttt gcggcaccgt
    14821 ctacaatcat tttataggtc gtatagattt ctccataccg atccatttga tcacggaaaa
    14881 tatttgtaaa taagaacagt tctggtttca tatattctgt gactttgctc aaacttgctt
    14941 catctatttc taggacagca aactttttct gtcctttttt tggttttgcc tgcaagaaag
    15001 tcgatacaat tccctgtacc atattcgcac cagtagggtt ggttagaact tcatcgaatt
    15061 gctggcgcaa aatattgact gttaaagcgg tagtcaatgt tttaccgttt gttccggtga
    15121 caacgacgac ttggtagtct tttgccaaac tatctagtat atgtggatcg actttcagcg
    15181 ctagtttacc tggtaaactt gatccgcctt taaaaaaagt ttttaatgcc cattgcgacg
    15241 tttttccaac tgcaatcgca aaatgactgc gtattcccat tatgtaacct ccaaaaacga
    15301 tttgctgacg aataaattca actaatcata ccatatgttg aaaaaaaggt taaattgctt
    15361 ttcttattct taagaaaagg ttacggctga aagtgcatga aatcggacaa aatcgcatga
    15421 tttaacaaaa aaacagcttg aaacaaaatg attgtttcaa gctgctgtga ttttattatt
    15481 ccctcttacc tatattccca ttttaaccga taataatttt ctcgcttgga tattcatagc
    15541 ctagatctcg tgtttctttt ggcacgaata acatcaatgt atatagcatt ccgatccgcc
    15601 caataaacat cagtgtagca atcgtgattt tgcccacaac agacaagtct ccggtaatcc
    15661 ctaaagataa accagttgtt ccaaacgcag aagttacttc gatgatgatc gagatcagcg
    15721 tttgttcttc tgtagcagat aaaaaaacga tacaaaagaa acacatacca agagaaagca
    15781 taaagacaac gactgatttt cgcacatcat cttgatcgat tctccgtcca aaaatattga
    15841 tgttatcttc acttttgagg aaggaatata gatacaaacc gatgattgct acagtagttg
    15901 ttcgaatccc gccgcctaca gaactaggac tgcatccgat aaacatcagt aaagaaaaaa
    15961 tgatcagtgt tgtgatttga aaatcaccca aatcgtgaat ctgcagacca gcattacgag
    16021 tcgtaatcga ataaaacatc gaattgatcc atttgacact catattggaa tcttggaata
    16081 aatggtcctt ttccaataga taaatcaaga cagttcccga aacaaacaag ataacaaaag
    16141 ctaacacagc taatttggta aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt
    16201 tgtataatag ccattcccgg cactccatca atacaggaaa accaattcct ccgacaaaaa
    16261 tcaaaaacat gatcaggatc aagaaaaaat agtcatgtgc aaagggcttg atggaatccc
    16321 cagtgacgtc aaacccagag ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa
    16381 cggcatcacg ccaacgatca aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc
    16441 caaaaagtaa ttgaaaccag attaaaatag caaaagtgat ccgaatcagt cggacgatac
    16501 cagacaaacg cggttgattc atatccgtca tgatcagctg tcgctgtttc agtgtgatcc
    16561 gtcgtttaga aaaaatgaca aaagcagtag aaatcatcat gatccccaaa ccaccaactt
    16621 gaaataatat ttccagcagt ataataccgt tatcattgaa cacagaattg atatcaaaag
    16681 tcgatagtcc agtcacactc actgtactga ttgccatgaa cagcatgtcc acaaaagaaa
    16741 catggctatc tggttcgcga aaaatcggca tataaaatag aacgagtgat aagaccgtca
    16801 tcaatatata ataaaaaacg atgatttgga tcgatgagaa atgattggca gcaaacttct
    16861 gtcctcgccg ctgcagcctt cgaaagaata aatcaacatg cacagtacta tcctcctgac
    16921 aatagtcgtt tctaccagta tacaagggga attaggaata ctcaaagaaa ttatcaaaca
    16981 gataacaata cagctttcga ttaaaataga aatggcttat aataaggaaa atcctagaaa
    17041 aaagaaggag gaggaataac aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa
    17101 atcaaaaaat aaattatgat acagttctga aaaaaatgat catgcaatgg gagaaagaag
    17161 aagtaaagcc taagatatta atacatacat gctgtgctcc ttgcagtacg cacacattgg
    17221 aattcatgtc tcaatatgca gagatcacgt tatttttttc aaattcgaat attcatccta
    17281 aaagtgagta tttgcgaaga ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga
    17341 aaactgacca tcatgttgcg ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa
    17401 tggttttaac aaaccatctt gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct
    17461 tcaatatgcg attagatctt gttgcgcaaa aagcgcaaga actaggatac gattactttg
    17521 gaagtgccct gaccatctcg ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg
    17581 atatccaaaa gatttacggg acacaatact tgccaagtga tttcaagaaa aacaaaggct
    17641 atgaacgctc tttgcaaatg tgcaaagagt atgatattta tcgccaatgt tattgtggtt
    17701 gcgtgttcgc tgccaagcag caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag
    17761 cttacttaaa aacatcaacc gtagtttttg aggaaaatta aagaaatctt tcggaaaaac
    17821 gtaagaaaaa aataaagaat ttatggtaga aataaggtag actgtataat ttgtccgtag
    17881 taaagtaagg aaacaagaat aaatttcaat gaaggaagag ataagatgcg aaaagtagca
    17941 cctattttga agccaatcgc tgtattaaca atctcgacga ttgtcgcgac tactacaggt
    18001 attgtgaata gttccagcta ccgtgcacca agttcaagtt ctagtactgt agaagaaaca
    18061 acaccaacta cttcagtctc gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc
    18121 actacgacaa gtacatggga cgatacaaca actagttcgt cgtatgatga gacatataca
    18181 actgacagct caagcgaaac aagtaatacg gtaccagatg gcactccatc ggattcaacc
    18241 aatccaagta caagtccgga tacaagtgct agctccgaaa cgataccaag cagtacgact
    18301 gtagatgata acacgcaaaa tgatgatgca gcacgtacag cacagcaaaa ccaagattca
    18361 ggaaataccc aaacgtataa ccagcaagca ggtgattctc aatgacattt ttactagacc
    18421 ttatcaacgg ggtgcataaa ttccttggct atttagacat cagtcctaaa tatcttaacc
    18481 gtggatatac gattttaagt gtgattccca cgctttattt attgagaatt gtttatggac
    18541 tttggcaaaa ccaaaactat cttcaatttt tcttatatgg acttgcattt ctagtgcttg
    18601 tttattttac tgttttaaat gtattttatt actttttaga taaaaacacg aaagccgatg
    18661 tcactcagct ttttgtgaag tatttacctg atgaagcgtt caacatccag acagaagaat
    18721 cgatagataa tggaaattcg atcgataaag tgaatacaca agaggtcatg gtttcttatg
    18781 acgaagatta tcaattgaaa ttagccgaga atatgcggta tttgattgga aatggtgaga
    18841 tcaaaacaaa tgaactcggt cgcatggatg gatttctggt cgatagaaat acattgtatc
    18901 cttattacta tgtcaagaaa acaggagaga aagagtatgt tctaaatatt ggacgaagct
    18961 actcggacat ggaaaaagta gggaccattc gacttgactc aacagaagac acattggaac
    19021 ctgtcggatt gttcatcgtc ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc
    19081 cttatcgtct gaaattgatt gcaaaaaagg cacagtcgca ggaagaacca gtggtttata
    19141 gtcgtagcca aagaagaaga cattcataat gtgatgaaac gccgtgtatc agtggttgcg
    19201 ataaaaacgt ttattcggaa taagggggat gtgacacgtc ttttgtcacg ttcctttttt
    19261 atataacgag aaagataaga cgaacacatc acttattctt tcctttcatt tataaacatt
    19321 gtagaataaa gaaagtacaa cgaagtattg tgaaaaaacg taataaataa cgaggaaaat
    19381 acaagtagga ggtaagctgt gaaagaattt ttgaaaaatt gggggatttt gatccttgta
    19441 ttagcggcta ttttattagc tagagtgtac gtgtttacac cagttactgt aaacgggcat
    19501 tcgatggacc ctacattaag tgatggacaa cgattgattt catctaagat ctcaaactat
    19561 gaacgaatgg atattattac tacaaaggaa ccgggggatg aagaacggat gattgttaaa
    19621 cggatcatcg gtatgcctgg agatacagtc aagatggaaa atgaccagtt gaccattaat
    19681 ggcaaaaagt atgatgaacc ttatctggat gagttcaaaa aagaattttc agaagataag
    19741 ttacaaggag aatatgctta tagctcagga ttccaagcac aagcagaaag ttcatccacc
    19801 tttacgagtg actttgaata tactgtgcca aaaggaaagt atcttgttct aggcgataac
    19861 cgcttgattt caaaagacag ccgaatgttt gggttagtcg acaaagatat gatccaagga
    19921 aaagttgttt tccgttattg gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa
    19981 aagaagctgt gacatgtttt ttgtcacagc ttctttttcc gaaaattcct tcttatttct
    20041 tggagttgct cacttttttt gcaatctcat tttaagcttt ttggctgatg gataagaaaa
    20101 gcgaagcgtt tttgttcata aatagctttt ccccacgatg gaaggtatga ctagtagcag
    20161 agacaaagcc cgttttttcc aatcgattat tcaattcttc ttggctaaag ccattatgga
    20221 ctttcggatg actaatttgt tcattcttgt caaagtctac gatgatcaat tgaccgccag
    20281 gagctaaaat ttcataaagt tttgtaagaa tattctccgt atcaggaatg tgtaaaagta
    20341 caagtgatag aaggatgaga ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt
    20401 ggatcgttcg gacatttttc agatctgctg cttggatctt ttcttctgcc attttcagca
    20461 tagtttctga agcatcggca atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa
    20521 caagcccagt tccgcctccg taatccagca ggactttttg gtggctgtcg cgcggtagat
    20581 aagtagttag ttcttcgcga ataatcttgg ctaatgcttg acggtcaggg gaatcataat
    20641 ggttagcgat ggaatcaaaa atattttttg tcatcaaata gctccttacg taaaactttg
    20701 aaattttaac ttattatagc acgtgaaaag aaagaaagca tgctatactc aattcaaaaa
    20761 gggagaatct agaaagaata tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa
    20821 gtgtgtccga gaaatattac tagacttgcc tgagtggttt gggcttcctg aatcaacgga
    20881 aaaatatatc gaggaatcaa gtaaactacc tttatggtgt gaaaaaagaa aagaagaata
    20941 tttaggcttt atcactcttt cacagacaag tgaagatact gccgaaatct attctattgt
    21001 atgggaataa aaaaagacta tcatcaccaa ggattaggaa caaaactttt taaagaagca
    21061 gaaggttacg cagcaaaaca ttacaaatat ttgcaagtga agactgtaga cgaggggcac
    21121 tactctatat atgatcaaac tatttgtttc tacgaatcat taggattttc aaggttggaa
    21181 gtttttccaa atttatggga tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa
    21241 caaaagtgag caatagattt aatactaatc tgtgcttgat gaaaattctc actgtaaaaa
    21301 atgctgaaaa tcaagtataa taccatagga acaaactgga aggtgaaaaa gagcatggca
    21361 caactatttt ttaagtatgg cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc
    21421 gcacataatt atgaagaaca aaataagcca gttgtcttaa tgacaagcgg tattgataca
    21481 agagatggtt taggcgttgt ttcaagccga atcggactga aacgtaatgc gatgccgata
    21541 tttgaagaaa cagacgtatt tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg
    21601 ctgatcgatg aagcgcaatt cttaaaaaag aaacatgtca ttgcttttac gagaattgtg
    21661 gacgaattgg atattccggt tatggcattt ggtttgaaaa atgattttcg aaacgagtta
    21721 tttgaaggat caaaatattt attgctttat gcagacaaaa tcgaagaaat gaaaacaatc
    21781 tgttggttct gccacaaaaa agcaatcatg aatttacatt atattgatgg aaaccctgtt
    21841 tatgaaggcg atcaagtgca aattggcgga aatgaagctt attaccccgt ttgtcgaaaa
    21901 cattactttc acccatcaat gattacagaa ggagaataag catgtacgat caattacaag
    21961 caattgaaga ccgttatgaa gagcttggag aacttttaag tgacccagaa gtgatttctg
    22021 atacaaagcg ttttatgcag ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag
    22081 tttatcgtcg ttataaagaa gtagtacaag gaatcaccga tacagaagaa ctgcttggtg
    22141 aaaaactgga tgatgaaatg gctgaactag caaaagaaga attatctgaa ttaaaaaaag
    22201 aaaaagaagt cttagaagaa aaaatcaaga tcttgctttt accaaaagat ccaaatgacg
    22261 ataaaaatat catcatggaa atccgtggag cagcaggcgg agacgaagca gcattattcg
    22321 ctggcgatct tttcaatatg taccaaaagt atgctgaagc acaaggctgg aaaacagaag
    22381 tgatggaagc taacgttacc ggaatcggtg gatataaaga agtgatcatg atgatcaccg
    22441 gagacaacgt atattcgaaa ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc
    22501 cttcaactga atcgcaaggg cgtatccata cttccaccgc aacagttgtc gtgatgccag
    22561 aagctgaaga agtagagatc gatattgaag acaaagatat ccgtacagat atctatcatg
    22621 cttcaggtgc tggcggacag cacgtcaata aaacagcatc tgctgtacgt ttgactcact
    22681 taccaacagg gatcgttgtt gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa
    22741 aagcaatgaa aatcttgcgt gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg
    22801 agtatgatgc caatcgaaaa tcagcagtcg gaactgggga tcgttcagaa cggatccgga
    22861 cgtataattt cccgcaaaat cgtgtgactg atcatcgtat cggattaact atccaaaaat
    22921 tagatcagat tttagcaggg aaattagatg agatcgttga tgcattgatc atgtatgatc
    22981 aaacatcaaa actggaagct atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca
    23041 cgggcttctt cttttttaga ggatcatggg aaagaagcat atagtatcca atttttattt
    23101 ttggaacgaa aacaatggaa aaaacttgat tggctccttc atatgaacga agagatttca
    23161 gaagaagaac agcggttgat cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct
    23221 cagtatttgc taggatatgc agatttttat gatcatcggt taaaggtaac tgaagcaaca
    23281 ctgatccctc gaccagaaac agaggagtta gtcgaatggt gtttagacga gacgcctggt
    23341 gtaccgttag aagtgataga tattgggaca gggactggag caattgctat tagtttgaaa
    23401 gcagcaagaa aaaattggca tatatctgct gtggatcttt cagaagaagc attagaagta
    23461 gcgaaagaaa atgctcagaa agaaggaacg aaaatcagtt tttatcatgg agatacatta
    23521 ggaccagtaa tggatcagca atttgatgtg attatttcta atccgccgta catcagtcgg
    23581 aatgaatggg aactgatgga tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt
    23641 gctgagaacg atggattagc tatttatgaa aaaatagcag ttgaagcacc aagcgtacta
    23701 aaatcaaatg gaaagatttt tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa
    23761 atatttcagc aagcatttcc agataaaaaa gtggcgataa aaaaggatct ttttggcaat
    23821 gaacgaatga tccaagttta tggttgaagt tgtggatgaa aaatttttta tttgtttttt
    23881 tattataaaa aaacacttat ttgacaagga tgtaaacgac tttttggttt atcaacaagt
    23941 ttatccacta ttgacaaata gattatccac aaacagtgga aaacttgagg ataaactcag
    24001 acaaaataag aatgtatgaa aaaggggttg tggataaact gtggaaacga aacgatatga
    24061 tgaaacagaa ttgcaagagg cagccgaagc actgaaagaa ggagaacttg ttgcttttcc
    24121 taccgaaaca gtatacggat tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt
    24181 gttttctgta aaagggagac cgcaagataa tccattaatc gtccatgtcg cctcttttga
    24241 acaagtaaaa gagtatgtgg acaactttca tccggcagca gagaagattg tgaagaactt
    24301 ctggcctgga ccattaactt tgatatttaa gatcaaaaaa gacactttgc cctcagttgt
    24361 gacgggagga ttatccacag ctgcatttcg tataccggat aacaaaaaaa cactagaagt
    24421 aatcgaactt tccggtgttc cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag
    24481 tccaacgact gcagatcatg tatatcatga tctacaagga aaaattaccg ggattattga
    24541 tgatggagct acgcgaattg gtgtagaatc cactgttctt gatttaagtg atccaacagc
    24601 catgcctatg attttacgac caggtgcagt aacgaaagaa caaatcgaag cagtcatcga
    24661 atctcctgtt gctattgatc agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg
    24721 gatgaaatac aaacactact cacccgatac acgtgttctg atggtcagag atggcgattg
    24781 gtcaactgca gttcaatggg caaaaaataa gaagatccgt gcaggtgtca tagcaagccc
    24841 cgaaattgcg gatcaagtgc ggacagatac tgcagctgtt tatatgtata acgacaactc
    24901 agtagaagcg gcggctaaag gattgtttgc aggtctaaga ggattagatg aaccaacact
    24961 tggattagat ttgatttttg tacaagtgta tccagaaact ggattgggga atgcttacat
    25021 gaatcgcttg aaaaaagcag caggacaaaa ttattttgaa aaatgatcaa ttggttattg
    25081 tcgcattctt ttagtatgat acaatgctat caagtaaatc ttctatcagt gaacgaaaaa
    25141 ctaagcgtaa ctaatcgtaa tagaagagat acgaatattt ggcaatttgt ttttgatggg
    25201 aaaaataaaa ttgtaggaaa ataaaaagga gctgttgttt gtggtagatt acaaaacgtt
    25261 tgaccctgat ctttgggctg cgatcgccaa agaagaagaa agacaagaac ataatttgga
    25321 gctgattgcc tctgaaaact ttgtctccga agcagtgatg gctgcacaag gaagtatctt
    25381 gacaaataaa tacgcagaag gttatccagg gcatcgctat tatggtgggt gtgaatttgt
    25441 cgatatcgtt gaaaatttag cgattgaccg tgcaaaagaa ttattcggag cgaaatttgc
    25501 gaacgtccag cctcactccg gctctcaagc caacacggct gcttatctcg ctttggtaga
    25561 accaggggac acgatcttag gaatggatct ttccgcaggc ggacatctaa cacatggatc
    25621 accagtcaac ttcagtggca aaacctatca ctttgttgct tacggtgttg atccgacaac
    25681 agaagttatt gattataatg tggtacgtat tttagctaga aaacatcaac caaaattgat
    25741 cgtagcaggt gccagtgctt acggacgaac gatcgacttt gcgaaattca gagaaatcgc
    25801 agatgaagta ggcgcaaaac tgatggtaga tatggcacat atcgcaggat tagtagcagc
    25861 aggacttcat cctaatccag ttccttatgc agatatcaca acgactacca ctcataaaac
    25921 attgcgtggc cctcgaggcg gcatgatttt gacaaacgat gaagcattag caaaaaaaat
    25981 aaatagtgcg gtatttcctg gtattcaagg cggccctcta gagcatgtga ttgcgggtaa
    26041 agcagtagca ttcaaagaag cattagatcc tgcatttaaa gaatatagtg aacaaatcat
    26101 cgccaatgca aaagcaatgg tcaaagtttt caatcaagca attggaacca gagtcatttc
    26161 aggggcgaca gataatcatc tgatgttgat cgatgttcgc gagttaggta taaatggaaa
    26221 agaagcagag agcattttgg acagtgtgaa tatcactgta aataaaaact cgattccttt
    26281 tgaaacacta agtccattca aaacaagcgg tattcgaatc ggcacgccag caatcactac
    26341 tcgcgggttc aaagaagaag atgctgtaaa agtggctgaa ctagttgtca aagcattaca
    26401 agcaaaagat gataacgctc aactagacga agtcaaaaca ggtgtacgcg aattaactga
    26461 aaaatttccg ttgcataaaa aataaaaatt taaattccat tagtaaacag aaaagttcaa
    26521 tgttgggctt ttctgtttat tttttgggaa aacggattct ttgacaatat cggtgatgct
    26581 ctctagtata tgaggtgtaa ttttagtctt cacactaaat ctcagggagg aaaagtcatg
    26641 actgatcgta tctcgttaga aaaggaagca gtagcattca gtgatgcaaa tgcgcctcat
    26701 ccgcgtatct atgaactagc accggaagaa ggaagagttt tactagaaga agtacaagaa
    26761 tcacctgtga acaaatattc cgtcgatatt gaagacttga tggtggatac tggcgaatgg
    26821 ggaaaactca atattcgtct cgtacgacca gaagggaata tggataaatt accagttatt
    26881 ttttatattc atggagcagg ctgggttttt ggcagtgctc aaacccatga taaattgatc
    26941 agagaacttg cggttcgtac gaattccgtc gttgtctttc cagaatatag tcgatcacca
    27001 gaagcaaaat atccaacagc aattgaacaa aattatgctg tgttgcaaca gctgaataaa
    27061 ttagccaagt caaaaaatct ggatctcgag aatctaatcg ttgcaggaga ttcagtaggt
    27121 ggtaacatgg ctacagtcat gacgatctta acaaaagaac gaaagggcct cccaatatcc
    27181 aagcaattgc tgtattatcc agtcacaaac gctgattttg atacagattc ctatcatgaa
    27241 ttcggagaaa actatttttt gacaagagaa ggaatgatgt ggttttggga ccaatatacg
    27301 acgaatgaag aagagcgtgc tgaaatcaca gcttcgcctt tgagagcaaa tataaatgaa
    27361 ctaaatgatc ttccttcagc aatgatttta acgggagaag cggatgtatt aagagatgaa
    27421 ggtgaggctt atgcgcgcaa acttcgtgat gcaggggttc ctgttacaca agtacgcttc
    27481 caaggaatca tccatgattt tgtcatggta aatgctatgg atcagacaaa ggcaacgcgt
    27541 gcagcaatgg cattatctac ttcttggatc aagaaaaaag aataagcttt gcttgtccgc
    27601 aggaaaactt cttttcaaaa acggattttc ttaggaaaaa tggcgagttt gactagtcaa
    27661 tcacttgatt ttgttttaca attaaaaaga aacgacagaa caaaggagag cttaaaaaat
    27721 gggcaaattt caagtgatcg atcatccatt gattcaacac aaactaacta ttattcggga
    27781 caaaaactgc ggaacaaagg tttttcgtga agtagtcgat gaaatcgcta tgttgatggc
    27841 atatgaagta tcacgggata tgccattgga agacatcgtg atcgaaacac cgatcactga
    27901 aacaacacaa aaaacgttgt ctggtaaaaa agtagcgatt attccaatct tgcgcgcagg
    27961 tattggaatg gttgacggta tcttggaatt gattccagct gctaaagtgg gacatatcgg
    28021 tctttatcga gatgaagaaa cattggaacc acatgaatat ttcgtcaaac ttccagaaga
    28081 cattgatgca cgtcagttgt ttgtagtaga tccaatgttg gcaacaggcg gatcagcaat
    28141 catggcaatc gatgcattga aagaacgtgg cgcgtcgaac attaaatttg tttgtttggt
    28201 agcagcacct gagggagtaa aagctttgca agaagcgcat cctgatattg acatctatac
    28261 agcttctcta gatgaaaaat tgaatgaaca tggttatatc gttcctggac taggggatgc
    28321 gggtgaccgt ttgtttggta caaaataagt aaatacgaaa aagggtgtga cacaactttt
    28381 gtcacatcct tttttggtca tttttaacgt ttgatgcaga acagcttttt cacagctttc
    28441 gtttgcatat aaaaaaacca tcccaaaaat gcagagatgg tcaaattcaa atctttttta
    28501 gttctttgta gttaacgatt actacaccct tactttgcgt catcaagttc gcattttctg
    28561 cagtttcatc aatctcaaca acagcggaat ttttcaattg ctttgaaatc gttccagttt
    28621 gcgacttgcc gtgaattgtg aacattacgt gagtattgat cttgaatttt tcaccaattt
    28681 ccgatggtac gatagttgta tcaaattttc caaaagttgc cattttcata aaacctgcct
    28741 ttcacatcaa ttataccacg ttttatgaaa aatatcatga aattaaacta attttccatc
    28801 ggactcttta caatcagcca aatagagtat ataatttctt ttggataagg ccagcttagc
    28861 tcagttggta gagcaacgca ctcgtaacgc gtaggtcgta ggttcgatcc ctatagctgg
    28921 cattaaaaga gaagacagat atatcaagga tttttaatcc attgatacat ctgtcttttt
    28981 gtttaaagga aataaagtat gctttcttag caatagagca tgtattattt ctataaaaat
    29041 ttaggagaat aaaacgacta gcaatatagc tgtgaaatca aatatcacat gaactgccca
    29101 acttgtaatg atcgagttgc ttttaatggc agcttggttg aataacaatc ttgccacccc
    29161 ttgtatcaaa aggatgtgtg ctacagtgtg taaaatattt ccattatcat aagtactgta
    29221 atggataaat ccaaagatga ttgctgacaa gaaactagcg acaggaatgc tgaacttact
    29281 agaaaaaata gcgagaaaat acactgagaa caattcttct ccaagtatca tgataggcaa
    29341 aataataaat aataacgggc tgaaagcctc atttattgga ttgcctgtta aaccccattt
    29401 caaaatttgt tgcaaaaata ccgagactgc ggcactgatt actacattga taaaaaaata
    29461 tttggctata tttttgacag gagcgacagg tttcgagaac atttttttcg tatctttttt
    29521 accaaaaaca agtgtaaatg ctataaatcc agtgatagtt aaagaaaaaa tgctaataat
    29581 ggatggcgca aatagcaacc ctaacaaacc gagtacaacg acaatagtgc ccaatatccc
    29641 ttttttaagt tctatttttt ttcctaaaat gttattcatg ataataactc ctactattca
    29701 gtttttgaag atagagtcag tatacatgaa gagttaaaat aggcaatgtt tttttatgga
    29761 tatttgtatt gctaaaaatt tatcttatat attcattttg attatactac ttttatttgt
    29821 aaaaattttc tagcaaaacc aagtgcttgc aactgattaa gcgtacaatt ttttagatgt
    29881 tccgagcgta cttcaatcat ttcaaaggag ttgctactta aatcgatatt ttttaaatca
    29941 gtatcaaaaa agctagcatt ttctaaatca ttagtagaaa acattatttt agtgagggaa
    30001 cagtctacaa aatctgcgct tgataagaca gagtgctcaa aggtactttc ttttatgttt
    30061 gaaccagata aatttacata gtccatttta caattctcga ataacgtgtt cccaatataa
    30121 ctttccatca atttagtacc tgttaattta caattgacaa atttcacgcg atgcaacatg
    30181 ctttttgtca atatacagcc tgaaaaatca cagttttcga atatacagtc ggtaatctcc
    30241 attctttgaa aatcattgga agcaaaaaat gcatacttga aaatagattt gtaaataatt
    30301 ggatggcaga ttatttggtt ttcgatgacc tctttttgtg aaaggatatt atacagttca
    30361 aaatcttcgt tttcatagat atgaaaaaag gatcctttat tcaagcttgc ttcattaact
    30421 ttaggaaaaa tcatatttaa ttacctccat tttcataaag tcatattaac aaaagctaaa
    30481 ccaacttaca ttagcagaaa atgagatagg ttttcgcctt tttcgataac gatagtgtcg
    30541 ctatctcttg aaacgttctt agaattgccc tgagagacac aaattaggcg taattctaat
    30601 aaaaatctta gaataaaaat ttttactgat ttaatttaga atgtttttaa aataaaaatc
    30661 gttgccataa cagtgtattg aaaggtttta acaatccagt aatgatttaa aaaaatctag
    30721 atgtagcgta tactttgttt atagaatgta gtgggaagaa atatattttt gggaggaaat
    30781 cgtgatgtct aaaagtgaag aaatagaaaa catggtacta aaattatatg atctcgtttt
    30841 aaatccagag atcaaagaaa aggaacgtat acttttgata gacgcaaaga caggcttaga
    30901 aaaaggtcag tattatccta aagtcataaa taatttggaa cgtagtttac gtccgttagc
    30961 aatcagggga gaattgtcta aaccagtatc accgttttat atggagatat caacaatagg
    31021 aaaatttgaa aaagaattag gtcgaggaat ggcttcggca ccgattactt ttgggcattt
    31081 ataaaaacga gttattcatc tcaatgaatt aaaaagtata gtcaatctca taatgcaggc
    31141 taggttcatt tatttgaaca gagtctgta
//
LOCUS       DADVXM010000024        30940 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.025, whole genome shotgun sequence.
ACCESSION   DADVXM010000024 DADVXM010000000
VERSION     DADVXM010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.025"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(726..1205)
                     /locus_tag="KB927_001208"
                     /pseudo
     CDS             complement(726..1205)
                     /locus_tag="KB927_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(1364..2065)
                     /locus_tag="KB927_001209"
     CDS             complement(1364..2065)
                     /locus_tag="KB927_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6840139.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(2173..3582)
                     /locus_tag="KB927_001210"
     CDS             complement(2173..3582)
                     /locus_tag="KB927_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBB6840140.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(3630..5495)
                     /locus_tag="KB927_001211"
     CDS             complement(3630..5495)
                     /locus_tag="KB927_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6840141.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHRGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(5616..6467)
                     /locus_tag="KB927_001212"
     CDS             complement(5616..6467)
                     /locus_tag="KB927_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6840142.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(6777..7490)
                     /locus_tag="KB927_001213"
     CDS             complement(6777..7490)
                     /locus_tag="KB927_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBB6840143.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(7558..7884)
                     /locus_tag="KB927_001214"
     CDS             complement(7558..7884)
                     /locus_tag="KB927_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBB6840144.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(8007..8234)
                     /locus_tag="KB927_001215"
     CDS             complement(8007..8234)
                     /locus_tag="KB927_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBB6840145.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(8556..9809)
                     /locus_tag="KB927_001216"
     CDS             complement(8556..9809)
                     /locus_tag="KB927_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6840146.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            9870..10610
                     /locus_tag="KB927_001217"
     CDS             9870..10610
                     /locus_tag="KB927_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6840147.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(10696..11454)
                     /locus_tag="KB927_001218"
     CDS             complement(10696..11454)
                     /locus_tag="KB927_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6840148.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(11451..12479)
                     /locus_tag="KB927_001219"
                     /pseudo
     CDS             complement(11451..12479)
                     /locus_tag="KB927_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(12499..15666)
                     /locus_tag="KB927_001220"
     CDS             complement(12499..15666)
                     /locus_tag="KB927_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840149.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(15890..16774)
                     /locus_tag="KB927_001221"
     CDS             complement(15890..16774)
                     /locus_tag="KB927_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBB6840150.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(16869..17306)
                     /locus_tag="KB927_001222"
     CDS             complement(16869..17306)
                     /locus_tag="KB927_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840151.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(17523..18434)
                     /locus_tag="KB927_001223"
     CDS             complement(17523..18434)
                     /locus_tag="KB927_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBB6840152.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(18891..19319)
                     /locus_tag="KB927_001224"
     CDS             complement(18891..19319)
                     /locus_tag="KB927_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840153.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(19347..19985)
                     /locus_tag="KB927_001225"
     CDS             complement(19347..19985)
                     /locus_tag="KB927_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840154.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(19989..21971)
                     /locus_tag="KB927_001226"
     CDS             complement(19989..21971)
                     /locus_tag="KB927_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBB6840155.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            22151..22816
                     /locus_tag="KB927_001227"
     CDS             22151..22816
                     /locus_tag="KB927_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6840156.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            complement(24751..27900)
                     /locus_tag="KB927_001228"
     CDS             complement(24751..27900)
                     /locus_tag="KB927_001228"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HBB6840157.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(27913..29112)
                     /locus_tag="KB927_001229"
     CDS             complement(27913..29112)
                     /locus_tag="KB927_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBB6840158.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLIDLVVRLNKSTNSSRLPKVEF
                     EDIVAGEGRLNKDVSQKFDNRKGIEFLPNDILYGKLRPYLKNWLKATFTGVAIGDFWV
                     FRAKKSDSDFIYSLIQADRYQKAANDTSGTKMPRSDWKKVSDTVFYIPNDLKEQQKIG
                     IFFKKLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWEERKLGE
                     LGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIERKKWKPI
                     KDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFETINLPR
                     YSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLLKETKKS
                     FLQKMFV"
     gene            complement(29102..30697)
                     /locus_tag="KB927_001230"
     CDS             complement(29102..30697)
                     /locus_tag="KB927_001230"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBB6840159.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEMWLQGALEVFKHEQ"
BASE COUNT         9026 a         6355 c         5031 g        10528 t
ORIGIN      
        1 agaaaaaaac atttttcagc tattttatag ataaaacaaa aataaataac gtgttttcat
       61 cgatgtgaaa tgacttactt atagaagata ctgggatttc gtcctatatg ccaataacgt
      121 gtattatttt aaacaacaaa tacttgtttc ttttattaac gaaaaaatca ttttgttctc
      181 gtgttatgtt tcactgataa atgatgtttc tctaaataaa aaagccgacg aactaaacga
      241 tcaaaatttg atcatttttg ttcatcagct tctcctaaaa atctttttgt taacgataaa
      301 tagctggatt tgtaaaaata tcacttgaat cgtcactgct ggaagaaaat tcagtgataa
      361 ccgcacctgt tgcgcctgcc tggaactagt gtttgatatt gggctcgaac gtgtactgat
      421 ctctagcatg aagaataatt tcttttttta ctgtataata actttctttc ctttttggaa
      481 tagtacagga aagttttttt gtttcctttc cttcgacata aggtatacca gaccctttcg
      541 acaacgaaag gttctcattt ttccttcatc gtcatttcaa ggagggtgcc gatgctctgg
      601 acagtttcga tcgctcctaa accaaaatct gtatattcga ttctttctaa ctctgattct
      661 ttcataccat tcctgcctca aggtacatct attgtacttt tttcttgtaa tccattctgc
      721 ctctcctaac taattgtcaa atcatcccaa gatatgtctt cttcctcttt ttcttcttgg
      781 atgatttctg cattcggatc tactggtttt ttcaataata aaatggttat tcctgtgaca
      841 aaagaaccag ctaacaatgc accaatgaat gcccatggtc tggtcatcgt agcgactgca
      901 aacattcccg atgccggaat acggctatct gcgccccaaa acatgcttaa tccgccacct
      961 actgtcccac cgactcccgt tgctatgaca ttgcgtgcca agtcgttcaa tacgataggg
     1021 aaacatccct ctgtgatctg acagatcccc ataggaaaag cggtcttcaa tgtatcgatt
     1081 tcttgacgat tgagtatatt tttacgaatg attttcccta agaaataagc gatcgtcaag
     1141 ccgaatgggg ttaccatcga agctaaaatc aatacagtga ttggttcata gattccttct
     1201 gaaaatcgtg ccacaccccc ttatccagaa taaatggtaa tccagaaaca gccgtgtatc
     1261 tgcggtaata agcctaacca aacgaaaaat atgagaagct atttttgttt ggctgttctt
     1321 attacttgat gcagggcagc tttttcacaa cctctttttt tatttatgtt tcataatcaa
     1381 tatggtaagg atgcagctcc gtatggtaga ccgcctccga atattcaatc atttccccaa
     1441 tttgcgtaga cgatttccgt atccgtttga tgccgatctg tgcgtctgtt ttcagaattc
     1501 cttgttcttc ttctgttaaa aatactgccg agaaatcatc agaaaatgag tcaatagtat
     1561 atcctttttt cgtcagcaaa cgatacaaag attctttgcc aaattcttct ctgctgaatt
     1621 gcatcatttc ttgtggaaga taatgaacaa aataaatata aggctgattg ttcaaataat
     1681 ataagcgctt aaaacaaaca gcttgctcac cgaaaaagga aaacaaagga tcttccttct
     1741 ttatatggac caattgcaaa tccagcgttt ctttccggac ttcatatcgg gagttctcca
     1801 agatttgcgt aaagcttgcc gctttggata atcgattgta aggacgattg cttagaaccg
     1861 tcgtcccacg accacttttc tttgcgacat attcatctga tgccagcagt tcgattgcct
     1921 ttcggacagt gattttgctg acttgaaaca gttcttctaa ttcactttct gtcggcaaca
     1981 tcgaaccgac tggatatttt cctgagaaaa tatcttcttt aattttatct gcgacttcca
     2041 agtatagtac acgtgtcctt ttcataacgt caccctttgc tttactatta ctaaaagaat
     2101 agcacataaa aaataaaaaa agaacacaaa tcacatgtga gaagtgtgtt ctttttcatt
     2161 cagctgcttt aattacaagt ttacgccatt tgaggcaatt acttctttat accaatcaaa
     2221 agattttttc tttgatcgat tcagtgtccc atttccttca tcgtctagat ccacatagat
     2281 aaagccgtaa cgtttactca tttctcctgt tgatgcactg acaagatcga tacatcccca
     2341 aggcgtatag cccatcaaat ctacaccgtc tgctactgca ttagccatcg cttcgatatg
     2401 acgacgtaaa taatcgatcc gataatcatc aataatcgtg ccatcctctt ccatatgatc
     2461 aatggctcca agaccgtttt caacaatgaa taatggtttc tggtaacgat tgtataattc
     2521 attcaatgcg attctcagcc cttctggatc gatctgccag ccccattcac ttgcctcaag
     2581 aaacggattt tttactcctc ccagcaagtt cccttctgaa gttgctgctt gtggatcagt
     2641 ctcattgatt gccgtagaca tataataact aaatccgatg tagtccactg gatattcttt
     2701 tagcaactgg aagtcttttt ccgtttgctc taatttttcc ggatcgactc catatttttt
     2761 atgggtacgc gctgtgtatg cagggtattc tccacgtact tggacatccg tgcagaaaaa
     2821 attgaattct tggttttgga tcattgttgc tgcctgattg actggattgg catcgatgct
     2881 gtaagttgtt gcatagataa tcatgcagcc gatttggata tccgaacgca attcgtggcc
     2941 gatttttacg gctttgctac ttgcaacgaa ttgattatgc catgcttgga aaatattttg
     3001 gtactctcct gctccattgc tttttactaa tccttgactt aaagctggaa agtgaaaggc
     3061 cgaattgatt tcattgaaag tcatccaata tttgacttta ctgctgtatc tctctaatac
     3121 tgtctgagca aatcgttcat agaagtcgat cagttttcga tttttccagc caccgtattc
     3181 ttttgccaaa tgaagaggca tttcgtaatg agaaatcgtg atcacaggtt caatatcata
     3241 ttttaagcac tcatcaatca gctgatcata aaattctaat cccgcttcgt taggagtacc
     3301 ttcgtctcca tttggaaaaa ttcgtgtcca ggcaatcgaa aaacgataac atttgaatcc
     3361 catttccgca aacaaggcaa gatcttcttt gaaacgatcg taatgatcga ttcctcgatg
     3421 attcgggtaa atatattttt cttgatcaat cgtccagtca aattcttcac tgccgataat
     3481 cgcaaagcgc tgcttacctc caggcatagc atctgcaacg gatagtcctt ttccgtctcg
     3541 atcataagcc ccttctaatt gatttggcag cagttgctcc accccataaa aatttttctg
     3601 aaaaacgtga ttgcatcctg atttcctcct tattttacaa ttgccagaac atcttcgttt
     3661 gcaataatct ctttttggtc taattcaagt atatcggcaa atgcatcagt attcgtaatg
     3721 acaactggag tgattacgct atagccagct gctctaattg cttcgatgtc aaaacgaatc
     3781 aataaatctc ctgctttgac gagatcccct tgtttgacta agatctcaaa gccattccca
     3841 tttaattcta ctgtatccat cccgatatga atcaaaatct ccgctccgtc agtcgttgtg
     3901 atccctacag catgtccagt tggaaaaata gtcgtgatct ctccgtctgc aggtgcaact
     3961 agttctccta cttctggatc aatagcgata ccttttccca tcacgccaga agaaaaaact
     4021 tggtctggta cttcactcaa tggcagtact ttacccgtta aaggactttt taaggtatgc
     4081 cgtgctgaag taatcggttc tcctgcattc gcatgtttgt tttctaattg attgtcttgt
     4141 gtttgttcgt caaatcctaa aatcaatgta cctacgaatg caagaacaaa agcaattcct
     4201 gtagctatta ctgctactgt cacatttgac tctacaccat ccaccgtatt aatgaaagtc
     4261 ggaatcgtca ataagctgac caaactgctg gagaaagctt ttactccgga aaatccgata
     4321 atagctccac caatacctcc agaaatacaa gcggcaatga atggtttctt caaaggtaat
     4381 gtcacaccat acacagttgg ttcagtgatt ccaaataacg aagtcactgt agaagaaatc
     4441 cctaatgctc gaagtttcgt atcttttgtt cgcaatgcta cagctaaagc agccccacct
     4501 tgtgccaaga tggctggaag aagcattggc atcaatacat caaacccata ttgttcgata
     4561 ttcaaaaaca tgatcggtac gaatccccga tgcatgccga acatcacgaa tacttgccat
     4621 aaacttccca tgattagacc tgctacgatt ggactaaatc cataaatcga gttgaagaga
     4681 ccgcctaaag cattaccggc aaccgtcccg attggtccta aagcaagaaa tgttaatgga
     4741 accatcacta ctaaaacgac aagcggaact aaaatcattt gcagaaattg cggaatcact
     4801 ttttttacga atggctctaa tttactttga acccatacgg ctagaatgat tggtatgaca
     4861 gaagaagtat aaccagatgg tgaaagaatc actgggatcc caaagaaact gatagcttct
     4921 cccgcaccag caactgctgt gatagctgga tacacaagtg ccatagcaat tgctactgct
     4981 aaaaactggt tggctttgaa ctttttagct gctgtaaaag caagcatgac aggtaagaag
     5041 gtaaagacac catctgctgc agcaaacaat atttgataag taccgctatc agctgtcagc
     5101 cagcccatca ccgttgccaa tgataagaat cctttcaata ccccggcggc tgccatcgcc
     5161 cctagaaaag gtgtaaatat actagagata atatcgatca gacgattcaa aatatttttg
     5221 gactcttctt ttccatcctc cgaaactgca agaccttcct catccacgat cgattgataa
     5281 acatctgcta cattactgcc aatcactact tgatactgac cgccactttg tacgacttgg
     5341 atcacgtccg ggtcttcttt taacttttgc gtatctgcta aagattcatc ttttaatctg
     5401 aatcgcaacc gcgtagcaca atgtactaaa cttttgacat tcttttgtcc tcctaccgct
     5461 tcccatacac gacgaccaac tgcttgatta tccattgttt tttccttctt tcttttttat
     5521 ttaaaaaata aaaacccaga ttgaaaaaaa cagtcacaaa cattcgtgaa cctatttttt
     5581 caatccaggt tttgcctgcc atacagtaac aatccttatg attggatgct ttttttctca
     5641 cttactactc tttgaatatg aatcgttaaa taaatctgct ctgcgatccc catttcctgt
     5701 ttttgcgttt gtcgaagata ctcattgatc cgttcgacac aatgaaacgc ttttggatac
     5761 tttccttgaa ctaatgcgta gagaaattca tcttgctcgt cagatccttc ccctttgaga
     5821 taacgctggg caaaaaactg cagatgagta atgatacgct gataattcaa agattcttca
     5881 tcgaacacga tgccgaagaa tttactgatg atactcagta tatctcttac cattgtggta
     5941 gcggtcatcg tcacttgcat gtcttcgttt ccttgttggc tattcacaaa atgaaaggca
     6001 ataaaaccgg cttcatcctc agaaagttcc acacccgtct tttgtttcac gaacaaaaga
     6061 gcctctttcg ctgcttgata ttctttcgga taaaattttt ttgtttcaaa taataatgga
     6121 ttaggcagtt ggatattttc ttttgctcgt gtgatcgcat aatgaagatg atcggtcaat
     6181 gtcagataaa tattaggcga aaattcaact tttagtttat cttcagccag ttcgactact
     6241 tgtttgaccc attcgatctc ctctgccgga atatcagcca tcagctgctg gaattggttt
     6301 ttagcaaaag aatctcttaa aacaaattct ttttggaccg cttctggcga aatctcgtcc
     6361 ccaatctttt tttgaaaagc tagtcctttt cccatacaaa cgacttcttc cccgaatcca
     6421 tttttcgaaa tgacgacatt gttattcaaa attttatcaa ttttcatttt gcttcgccct
     6481 ctcaagaaaa ataaaaaaac ctagaattcg cctactgttt cttagctgaa ttctggtttt
     6541 gcctgccgta cagtaacaat ccatttctta ttcaaaatca tcataccatc gaatttttat
     6601 ttatgcaagc cttttcatat aaaaaataaa aaaactggaa cacaagtcta tctagaaaac
     6661 aaccaaatca gagatgcacc tctttgcgtt tctctttttt tcagcaaatt ggtttttcct
     6721 tatcgattca tatcctttgg ctgtttttaa tctgtaacga cttatgtccc agtatcctaa
     6781 aatgtttttg tctctagatt gaaagcagat ctcatatcat ctgtcgcatc ttttatcgat
     6841 gtaacacttt ccagttctcc ttgtacaact agtcgcgtga cggcgtccat gtcgccacaa
     6901 gtaattagtg tgacaatttc ttttccctcg acttcattca gtaattgggt atctgtagga
     6961 gcaacttttt ctttaaaaaa tgttttgtat gtatacacat tttctaaatc tgtcaaatag
     7021 atcttggcac ccatctctaa attttctagc ggtgtaaaca gcaattcagg gttcgttgca
     7081 cgatggcttg ctaaggcata atttcctttt cccatttctt gatctggaga taatgttcct
     7141 gctccgtaaa gtagtgacgt attatccaag cctttgaaaa ccggtaaatt gattgaaact
     7201 gaagggactg cgatactagc aatcactggt agatctgttc ctctcatttg cgacctcatg
     7261 accccttctg tcgtcattgg ttctaccgca tcaaagtcaa aactgacatc tttatcgtta
     7321 ttctttttca gatcttcttt tgttacattc gctatagcat atttatctcc tgtctctctg
     7381 acaaaataat ccttgatctg ttcattgaaa atcaaagcta gtcctactaa taacaagagg
     7441 aacaagagga tattgactag ccatcttttt gcttttcctt tttttttcat tttctctccc
     7501 tccagactca ttttactgtt tttcttttgc tctttccaac agccgaatga cacatttcta
     7561 caactctgtg tatttttttc gtacacctgc gcttttttct acaggatatt tcaaattatt
     7621 tttgatcaat ttttcttcaa tgatctcatc tagatccagg tgaaggttgt ctgccatcat
     7681 gtatgaatag atcaatacat ctgccagttc ttctttgatt cgttctaatt gtgtttcttt
     7741 tacttcttcc ggcgttttcc attgaaaaag ttctaacaat tcagatgctt ccaaagaaat
     7801 agagatagcc aaatcttttt cgttatgaaa ttgtcgccaa ttacgttcat ctctaaactg
     7861 gttgactttt tccatactat tcatttgctt gccttcttcc aatcacttct tacttgatta
     7921 atcataccat ttttttacat aaaaaataga tgatgctttt aaaaaaactc ctgttttctt
     7981 ttatttaaaa taaatgtcat agaaaatcaa taatttaggt agccaccatg tgtatgcagt
     8041 agcgtgtctt cttcccttga ggctttttgt ttttcgatac gttcttcttc ccaaacagac
     8101 aacgctacta gaatctctct taatgatttt ccttcttcgg tgagcgagta ctctacttta
     8161 ggcgggactt ggttataggc ttttcgatgg atactttcat cttgttctaa ctctcttaac
     8221 tgctgggtca gcattttttt tgtgatcgta gggatttgct tgcttctcca cgcctaaaat
     8281 aagcgatatt gctcttccct ttatctggtg taagcaaagc agttagcatt ttgacgatcg
     8341 tgggttccgc ttttcacttc ttatctactt agtatcatga agtatacttt cgtactaata
     8401 ctaagtagcg gaagtgtcaa ctactttgtt taactacata gcaaaagaaa cagaagggtg
     8461 acaacggtca tcacgcttct gtttcttttg aatatgctgt gttgttgtct ctatctccgt
     8521 gtagactttc ctcaaactta tcctttgaca gtaagtcagt aggctgattt gctctttcta
     8581 gatgccagat acatttctac aaaaaaatag tgattctgtt ttgaaaattc gatttttagt
     8641 tctgcatttt cgtaaacatc caacattttt ttcgcactgt atagacctaa cccgccattt
     8701 tttttagagg tttttcctct tttgaccatc tccgatagcg tcaaattcgt tggatttgcc
     8761 ttgttcgcta tactaaaacg tgatccctct ttttcttcca gcagattgat cgtaatcgga
     8821 ctctgatcgg ctacacgatg atcgaatgcg ttagaaataa aaatagataa acagcgaata
     8881 aaaacaacca gatcaatcgg gattgttttc acttcgacag gaataactac ttggatcggg
     8941 attttctccg attctgcttt ttctagaaat tttaaaaaga cacccctgac agctggggat
     9001 acaatatttg ttagctgttg tatttgcggt ttttcaaaaa tagctgcaga atgatcttct
     9061 aatatttcta aaaattccaa cgtttctttt ttattttcct gaagagtaat ttttaatgaa
     9121 aacagtagac ttttataatc atgtttgaat tcctctagat gatggtaata ttcttcattt
     9181 atttgataca gttgaagcga ttcctgatgt tgtctttctt ttacttggaa actgatcaac
     9241 ataatggaaa aaaacaaaga aaaaaaactg atgactatcg acaaaagaga tagaagcaga
     9301 taattagatg agcggaagtg aacacttccc aataccaagt aaatcacgcc ccagcttaat
     9361 aaaatacaaa tacctccaaa atagtgttca gttggataag taaaaagcaa gttgagaaat
     9421 ctcgtctgtt tgtctatact ttttactaat agatagaaaa taaatgcgat aagtagtgca
     9481 aaaaaacttg ctgttccaag atgtctcttt cctaaataat ccatcagatc aaaaaccaga
     9541 aaaaagctga gtccagtgat agcaaaaaaa agattactga tcaaacagct gataaacagg
     9601 tttttcgtag taaaataaaa aagaaacatc aataataagc caactaggta aggaaagctc
     9661 actttaggga taggaagtaa aagtgtcacc accatcaaag ctatacaacc aaagctgttt
     9721 tttactagca gttgtttcga aaagaataaa tagataccta aatctaaaat caaagtaaag
     9781 gtcaaataaa gtgtcactgt tgcgaccatc ttattcctcc attgttttgt ttcaaaatgt
     9841 acacatattt ttttaatagg agcctgcata tgaaaaagta ttttatcata gaagataacc
     9901 agtttcacag cgaatggatc atcagagaat tggtcaatca tcatatcgag aatatcgtgc
     9961 agctcacttc tatctctcaa atcaatcagt tgatccagtt gggcactatt gataatcacg
    10021 atgttttctt tatcgatatc gacttgaagc aatcactcac aggtattgat gtcgccgaac
    10081 aaatacgtaa aaaaaatgca catagtaata ttgttttttt caccgcttat acgaattttg
    10141 cagtagagat catcaatcgg aaaatccttc cgattggata tatcagaaaa gacaggaatt
    10201 tatctgaaca aattcgtcaa gtgctagaac agatcaattg gaaagaacag cagatcgtaa
    10261 atgtcgataa aatctttatt gatcaaaaag gtggaagtct cgtcctgtat cctcgggaaa
    10321 ttttatatat tgaaagtatc aaaggtttga aaaaccaagt tatggtcaaa acaactacag
    10381 aagataaatt agtgaatact tctttaaaac aattgaagac agagttagaa aagtatgctt
    10441 actttttact tttaaaatct tactgtatca acttatcgca attgcagaaa attgattctg
    10501 ctcattatgt gttagaattt ttcaacggtg actccttact cgttggtcga aagatctttg
    10561 aaaagacaaa ggaacgtttc catgacttcc aaaaaactgc ttcgagttga tgaataagag
    10621 ctgagacgta agcatagcag atttcaggga gtgggccttg aatcggctcc actccctgaa
    10681 atcgttgata tgattttacg cttcctcttc tgtaggagca tctgttaacg accatgtgaa
    10741 tgttgaaacg tagttgtcta cagcataatt ggatacagga acaaataatt ccactgattg
    10801 tctcccttgt tccacattct ctcctaatga ataaatccat gtgccaatcc cttcatttgc
    10861 tcctgcagtt actagatcta ctgcctgatc tgctgggatt tcgattcctt cagcgccagt
    10921 tccagaaacg gtagatggca ttccactgct attagttgcg ctatttcgaa tcacggcgtt
    10981 tttgaatttc acctttgaac cagttagttt attcgtatca gatgttgtac caataaattc
    11041 tgttcgtttg actgataatt tccaaccggc ataatttccg cttttatccg ttacttgtac
    11101 gaaattctgt acttgtgttt gtgctccagt actgtccgtt ccgctttgta atgcagcata
    11161 tactgttttt gctgtaccta acttgattgt tccaaaatca agatctggag cttggtcaat
    11221 cgtcagtaat ccggatgttc cctgatttgg ttcgtcaggt gtaaaaggag tatcaggatc
    11281 atttggatca acaggaggaa ctggaacaac gtcttcagga tttgcagcat ctggtttggt
    11341 cacagaaatc gttccttctg tagtggctga gctcttattc tcagcaaaaa cactttgtgt
    11401 acataataat agacttccag ctagaacggt acttaatgca attgtttttt tcatttcttt
    11461 ttccttcttt cttttaaaat aaataatcca gcaaataagc caataagaat gactccaaca
    11521 agtatcagcc atcgccagtc aaatgtttct ggctgatttt ttaaatcaat atccttttca
    11581 ttcaattggt ccgctgcatc atcagttatt tcaaaatcgg tatggagatt ccagcgtttt
    11641 tctttccaag cacccttcac aaccgcttga taatgtcccg gagctaattt ttttccttct
    11701 aatgggacaa gtaaatcaaa atttgtattg ggtgctacat ctattttttc tttttttatt
    11761 gaaaggtaag gctcttttgt ttcttttttg tagatttcaa ccgatgtagt caagccgaac
    11821 atataagaag catttggatt ttgaagattc gccttaatca catttcttcc atcgctttga
    11881 tccgcataag ctttttttaa tttcaaatct ggggaagact ctttttcgct atttcaaatc
    11941 aagattgctt tcacttgaga aaactgattg acgacaccaa ctgtactttt gttagaaacg
    12001 ttctcttttt tttcttgaaa cgtgatccct cctgcgacca caccagccag ctctttttct
    12061 ggcgctttca gtgaaagtgt ctcagtgacc gcactttgag gaggaacagt tatttctccc
    12121 actgtttttg ctaagttttt catatcataa cttaatgttt catcaaattt actttttgat
    12181 tctccatatt cgatcacacc gtttgaattc gtcgtagcgg agtggatcaa tgtctcaact
    12241 gttactgatt tatctgttcg gttaaagacc gtgtagggga tttcctgtgt tttcccaggc
    12301 tccatcctta catttatata tgttttgttc ttatcaatct gattagccgg taattcaaaa
    12361 tctaccgcaa aattgaattc ggaggcatgg acaggtgtct gccaaaggat gaatccaagg
    12421 agaaggatca taagtaaaga gcagttgttt cgatgacttt tattccatat tcgattcatc
    12481 aatcatcctc cttgatcttt attctgtcgg cgcatctgct aatgtccatg ttatctctgc
    12541 tgagtaatta ccagctatct gattttcttt ggttaagaca agtttaaacg cccgaccgtt
    12601 atttaaatat tctgaataat ctgcttgcac attcgttgaa ttttgtcctc tgacaatttc
    12661 cagttcttct tcattcacta attgatactc ctctcctttc ttgaaatata ggacatcctg
    12721 catagaaaat cctgcatcat ttgtgaaagg ctgagataat tttatcgtta agatccacgg
    12781 atttttcgtt tctcgctgat cataaatcca taatttttcc tgtatatcca tttggccaaa
    12841 tgcttcttgt gtcaaaccag ttgctttgat ctgaccaaaa tcgagtttgg aaggggcaag
    12901 aaatgagaga ccaccttcta ctacgatctt cgtagcaggt gcaaaaggcg gggcatcatg
    12961 ataaacaact ggcgtatcac ttggattgtg attcccaatt tcatcgttgg tacttggctt
    13021 gttctgcaca cccttagcag tagcttctcc tgcttggtcg tttaatacaa tttctaatac
    13081 atctcctgca aaaagttgat tttctgggat agaaagaaca aattcccctg tatcatcaat
    13141 agttgtttct gacaaaacag cttgattttt tttcaatgaa accaaggctc ctgcttcacc
    13201 tgtacctgtg atcgtgcgag aagctgcatt gatcaatgtg gtacttaaat tagcaggttc
    13261 aggaggaatc acatcgactg tcgttttggc agagtccagt tctgtcactt cttggccacc
    13321 tcttactttt ttagcagcaa caacttgcac ttgatcctcc gtttttaatc tctcatcatt
    13381 gggtacttga acttcgaaca agccgccttg ttcgccttct ccccatgggt tatatcctgc
    13441 cccttcattt tcatctgttt gtccttgcgt gagagcagta atttctacag atgatttcgt
    13501 cgtatctgcg taagtaatac gtaaagtcac ttctacttcg cctgtccaag catctcttgg
    13561 ctttgcctcg acaccttcgg gaacaacgac atgcccatag atttttttat ctgcattcgt
    13621 tggcactctt aaggattcaa tcatcgggag ctgattattg gcactgattc gattataatt
    13681 tttcattccg gcacctgtct gagcaaattc atttgttaaa cctgcactag ggcttgatac
    13741 gaaattgcct aagtcggtcc cattgatcga taagtctgtc atatcagaaa aataatccgg
    13801 gtctttttca aagttatcga atgttgcgcc tgtttttcgc cataaagcga tttctgaatg
    13861 ggcgatcttt aaagaagaat ctccatttcc ttggaatacc cagccgccta tgccattggt
    13921 ctcgcttcca atccgtttgt tttggaaatc aaaataggta ggagattcta agtccacatt
    13981 caacacatcc ccactgatga tgccggtctt atcttcccct gttttcccga ccatgactaa
    14041 ataagttttt tcacctgccg taaaatttaa atcaatatct ccagttgtat ctacagttgc
    14101 tccggaatct gcgcgtatat cgatatttga tttttctcca gtgactgtaa aatcagctga
    14161 acctggactt tctagaaaac cagaagcgtc ataaaattgg atcgcttgat ttccttgatt
    14221 gagtctgttc acgtaagatt tgccatcacc tgtatttctt accctcaatg agcctccatt
    14281 ggttactgtc agcttttgcg taccattctc aaaacgaact gcgctggaac gcccactctg
    14341 cttatcgatg tcgataactg atccggctcc ttctacgatc aaagaaaggc cttttcctac
    14401 aaaacgcatc ccattgttcc cgggttgatc gtcatctcca gccattttga ccgagatttg
    14461 tccaccactt gatacatgga tttgactaga atctccttgc aagcgaaatc cgcccgtagt
    14521 tgctgtattg atggtgattt tcccaccatt cgatacagtg actttcgatc ctgaacctct
    14581 catttggatg attccgcgat tgttgtcatt ggtaatattg atctttgtat ttaccgaaaa
    14641 ttcgcttccc gaaccactga cttcaaacat gacattacca ggtagcgtat cgactgcctc
    14701 tccttcatcg ctaacgccat ctgcccgatc ataatcaaga gagacctttg aaccgcttaa
    14761 gatatggatt cctggcgctg tttttccact accagtctca tctcctgaat ctagaaaacc
    14821 gtagaatttc cctagatacg gtccataaag ttgactacca ttgatcacat tcaattgata
    14881 gcttctacaa aaataggctt tacccggagc ggcattcagt ccttccttca ctggttggac
    14941 atccaacaca ccggaaacac catctaatgt gacagttgca cgaggagcgt aaatcagtcc
    15001 taatttggac ccatcataca aatcaagtgt cccggtaaat tttatttctc ccgtaaaatg
    15061 atatctgctt ccccaaaaat cggtcatata agcaatgata atggcatttc catcgatatt
    15121 tggtgtcaat ccacctggat gtgcagctgt tcctttaaaa ttctggaact cgatcgactg
    15181 aggtatctca ttgatataaa tatggtgtgt gccgaaattg tgagcgaatc caccaaaatc
    15241 aataacgata tctcgtttga tctctaattc cctgtctaaa gtcaaaggct gaatcagtcg
    15301 gatcttagtt actgattcgt ctgcgagaag ctgcgccagt tcttctgttg tggcagcttc
    15361 gctgtaccca tccgctgaaa cagctcttgc cagtgccgct tcactgctat cagacgtttg
    15421 ttcagctact tctgaggtct cacttgtctt attttcttct tgccttttat tagtagaagc
    15481 ctcactttga gattctgtag tttcagaagt aatcgattct tctgaaaaag tagtcttgtc
    15541 aaaactttga ttctctgatt gcgttgattc gtttgttttc tctacatcgg caaaaacgga
    15601 tgtcaccatc aagagaggga agacaaacaa aatcgacgca atcagctttt ttacacattg
    15661 attcattctc caccatcctc tctgacgttt tgacaatttt attttatcgt tttaatctat
    15721 ttccaattgt actttcatat ttaaaatatg tatttttatg gaaaaatttt tctattaggt
    15781 gtaaatttct tttttgtaca aaaaaaaggc tgtgacaaaa gtcttgtcac agtcccttat
    15841 cccgaacaag cggtgttctc ccgccaactc ctcggtcaca acctccattt taacaataaa
    15901 cctgtaaatg tgagggcaat actttgattg tcacaggtaa tttatcccct tcatctccat
    15961 caacattcgt cgtcaattct tcctcatcag ctaatgacac aactaattgc tcacaagtaa
    16021 ggtaggctag atttttcgta gattcatcta ctccttttaa taggtctggc aatgttttaa
    16081 gcgtatcgat caaagaagaa tcttttaaat aaaccaaatg gagcttacca tcatccactt
    16141 ttgcatttgg aagtaatgtt tcaaaaccgc cgactgagtt agttagtcct atcagcaagg
    16201 tactgctctc aatttcttcc ttctttccat caacttctac gtgaaacgag taggattgtg
    16261 tggaagctaa ctgtttgatt cctgacatga aataagctag ttttccaaat ttcgtcttct
    16321 tctccgcatc tacatcattg attgattcag ggatagagcc aattgcgacg acattcataa
    16381 aatagtcgtc atttattttt ccaatatcca atggcttgac tgattcaatc gaaaaatgat
    16441 tgatcgcttc ctcaggttct agcggtatcc ctaatgctcg agccaagtca ttcaccgtac
    16501 ccaatgggaa aaatccgaaa tttggccgat gttcttgttc agcgattcca ctgattcctt
    16561 cgttgactgt tccatctccg cccatgacaa acacactatg atacccttcc gtagccgctt
    16621 cgcgagtaaa gttttttgca tcccctgctt tttttgtatg caagacgacc acttcatcaa
    16681 acaccgattc caattttgct atcgctaatt gctcaaattc ctttgcttgt tcaccgcctg
    16741 aactggggtt taccactaat aaaacttttt tcatcacttt ctttcccttc tgattgattt
    16801 ctttaatata acgatagcat aaagaaaaaa attaggctgt gatgaagtac tgttcatgaa
    16861 acattcattt attttttgac aagataaaac atccatacta tgaaactgag gaaaattaaa
    16921 acaatgatat aggaaataaa agaaaatgat aggcattgta tacctaataa agtaaaaatc
    16981 ttaggtggca gataaaaaca caaaaatagc aagagaatgt aatagcgttt cttccacttt
    17041 ttgttatcag accttatagc gatcagagga ataccaaatg cataactgaa aaactcttga
    17101 tgtactgtta atatgtcacg gccttgaata ataaatgcga caatccccgc tataattagt
    17161 gtgcctaaca ccaaaacgga aaattgatga atatatttta tatacaaatg atccattgta
    17221 cttcctgcct ttttatttgt gagaaaaaca aatccgtata cgtgaataac ttctagaaat
    17281 aaaagaaatt tgcaaaacca ctccatttat ctacttctac gtgcattttt tgatattgtt
    17341 ttctttattt aagattatac agaaaaatat ctagggtcgc tggattctaa gtaaaaaaaa
    17401 tttttaaaat aaaaagaact aaatcaagta gtaattaaac tactgttgat ttagttctaa
    17461 taaaaagatt tagatgaaca gttttattga tttaaatagt tcatattttt tatttatacc
    17521 gcttatttac tacttgctgt actagaatct gaagtgaatg tactcaaaac attttcaaag
    17581 tctttgtctt tgatttttac attagcgtct ttcaatactt cgccaattac tttattctgg
    17641 aaggtactgt cacttaattt tgtgtctgtt gcaatttctt tcaattcttt tttgtattta
    17701 tccatgtcgt tgcctttgtt ttggtttttc accattttaa ccacataata ttccgtagta
    17761 taagttgaag cattggtaga agtgatcaca tcagaaactt gaccatcttt caacttaaag
    17821 gctgcttctt tgacttctgc cggaaccgtt gtagtagtgg aatcaaattt cacttttccg
    17881 ccatcttctt ttgtcgtagt atcagttgac ttgtctttgg ctaatttaga gaaatcgtct
    17941 cccttatcag cagctttctt cacatctttt gcatcatctt cacttgctac ttggataatt
    18001 tgagcttcca cttctggatg gaaagattcc caagccgttt ttaaatcttc atcggtcaat
    18061 ttgatatgtt tctttagacc ttcttgaaag gctagacttt gtttgatact gtctttgaat
    18121 gtttgttctg tgtaacctgc agatttcaat tgtgaatcaa atgaatcacc caattgtttc
    18181 tttgtttgat catattgaga atcgatttct ttggttgata cgtcatctcc atatttatct
    18241 tcaaatactt gataaacgat caactgttgc acagcggaat ctgctccttg catttttttc
    18301 aagctatcca ttacttcttg ttcgctgatt gtaccgcctt tataactaac ggctgttttt
    18361 tcaccggcat tcgtacagcc tgacaataag ccagtgccta gtacgatggc aagtgctaaa
    18421 aatctttttt tcatttatca attctcctac ttttcgtttt ttgcgaattg ctaaaaacaa
    18481 aggtgttcaa gatgaaaatc atcaagaaca cctttactaa tctgctcgat acgtcctgaa
    18541 tagatataag gctacacaat ccagaaagtt cgctcagcag aataaatgtc aagtagcaca
    18601 tcacacctta atatactact tcttttgtta ccgtttttca agtctatctt gcgttccgta
    18661 tttaacgtaa ctaattctta gaacaaatgt tatcgatttt gtttttcttc ttccgctgct
    18721 gggatattca aatcagacac ttttatgttc gattttccag acattttttt gttgttttta
    18781 ttatgatata tttttataca actaaaaatg aatatattaa aactaccaaa aataactttt
    18841 aacgctgttt cattatatgt tttttctatt ttatataaac ttttggatac ttaataccaa
    18901 ccggttggat tgtaccaaca tgagaatgtg tcagttctat ttcctgtcgc acttgcatag
    18961 gcccatactc cttttgttgc atttgctgat cgaatagagt ttccaacttt cgcttttgca
    19021 ccgtgacgat tatagacacg actatagtgg ttagaatgac ctgtttttct cgtacaagtt
    19081 gtatcactat aataaaccca tcttccagag ctatgattaa ttgctgttct agaaatttcc
    19141 cggtctactg gtaaatttga cttaataata ttacctttag catcaaaatg aatctctcct
    19201 ggctttaaag atttgtaata gatttcaccg tgaactgaat ttgcttccac ttcagatgac
    19261 atagcgtttc ctccaacaaa acctatccct agtgcacaaa taataactgc ttttttcata
    19321 aaacgacatc ctttcctttt tgatttttaa agcatgatct tcttgtttcc tattttggtc
    19381 agatatggat catgcgtgac tacgataact aacgtacctt gggaagcttg ttgcgataag
    19441 atttcaacta ctttatcctt atttctttta tccaatgacc cagtcggttc atcggctaaa
    19501 atgattttgc tattcttcaa taagactctc gcacaggcga ttctttgctt ctcaccacca
    19561 gataatgtgt agataggcgt acttagcttc ttgtttatat ttactttttt caatgcctca
    19621 tactttgctg ttcgcttatc tgaaacattt aaattcgaaa acttcaatcc aatatctaaa
    19681 ttaaaatcga ttgtttcata ttcaatcaac ccaaaatctt gaaaaagaaa agatatggta
    19741 tttcttttta tcaagcgctt ctctctccca gttaattgtt tcgtctcttg atcgaacaaa
    19801 tagaattgtc ctgaactgaa ctgatcattc aatcctaata tattcaataa cgtactttta
    19861 cctgctccac tttctccaac aacagtcaca agatccccag catccgcagt gaaacgatcc
    19921 aaatgaagaa tcgttttgtt tcgaatgatt tttttcgcac cttttatcac tatcaacggc
    19981 tccaattgtt aacctccatt catcagcaat aactgacttt tcttttctgt agacaaaata
    20041 aaaacaactg aaagaataaa atcaatgaag ctaaagaaaa aaatattaaa aagatattta
    20101 ggctctcttt ctataagaaa aaggaagatt acacttgtcg ttccccattt gatgaggttc
    20161 atcatgaaga aatctttata cgtttcaaag agcgaataac cacttgaacg aaagatagcg
    20221 attttccgac aattgtagac aaaatatatg cataacatga catagctcaa caagaagaaa
    20281 gaaaagaaag tgagtaaaaa tatctgtatc aagtaatgaa atgatctgct taacactttg
    20341 acagctatct cttcagtctg agtatacgga aatgataact gcaagttatc acgtaactga
    20401 ctttcttcaa tcagctcaaa taacctttct ttcgacaaag agcctatctt gatctttaac
    20461 ggtggataga tttctccgct gagaatattt ctttccaaat acatactgtt tttcaatgtc
    20521 agtatttcaa caaccggata atgttcgatc caggggatag aaggaataaa tgtataaatg
    20581 ggttgattgt tttttataaa tagaaatttc ggttcttttt cactgatttc ttgataatat
    20641 tctgttattt gcgccaggtc attttttaaa tctgtatgtc tatatcgttc agggatcaat
    20701 ataacagggt gcgtttcttt ttcggttatt tggatcaacc ttccagagac atcaatcaaa
    20761 ggaaatttct taagataatt cagatttatt tttatccctc tgccaaactg ttcattttct
    20821 tcattcaagt aatctgatac attgactaat atacttccgt ttttattcaa agtttcatat
    20881 aattcctgat ctgctgctga tgcaaaacga ttggaataaa taaaatccac gtggtttttc
    20941 ccgatggtta ctggataaaa tacatgatag tcctcaccag cgatttcttt tggtggttca
    21001 tgggaaacag ctaactgtga agaagaaaaa acgatagttg ctaattcgac attggcaacg
    21061 gtcaaaagaa gagaaaacaa caatccaaat gtaaaaagaa tgtattggat atagttgaac
    21121 gcttctctta acgaagcgat tttttcaact aataaaagag aaatcaaaga gataccatat
    21181 attccgctga acaagaaaac gtacatctgg aacaaataaa gaaattgctc cttataatac
    21241 ataaaaataa aaccaccaat gattcctgca attatgaatg taataatgat tttctttttc
    21301 cccaataaac accacaatac ttgatgtaat gaaaagtcat tattcaacaa taaactgatt
    21361 tctttattca tcaataagaa aaaggatgat aacaaaagga ataaaagaat caatccaata
    21421 gttaaataca ctcgataatt atatacgtct gtatttgaaa taaccgaata cgaatagcta
    21481 ttttcaaagt cttcaaaaat attagtggca taatcagtgt gaaatgcttg attgaatcga
    21541 tcagtgaata gtgaaatgac ccgttcatag gcttcttttt ctctcgtcat caagaaaaat
    21601 tcaccttcaa aatcttttat tttgatcgat tcttcaatgg acgttacgcg aaaggaggta
    21661 ttagaatagg gtaccttctc gtgagaagat ttgacatccc cttgataata caatgtcatt
    21721 tcaagctttg gctgtatctt gaagttccaa gatgtatcta cttcattgga ttcatttact
    21781 gtttttttca tataagaaag ctcagtttct gatgagacat tttcaaatac catgattagc
    21841 tgctcatatt cttcttgccc aataaaatgt tgtggcaatc gaatcggagt ataagtatct
    21901 gtttgatgga aaaattcatt tgtccgatag agtacctgtt tatttatact aaccaaggca
    21961 aaaccactca tgataccggt cactatgatt gtgagtaaaa ctgtgaactt ttttttgatt
    22021 atcaccactc tcccttactt aaatgattct ttgataaaat cataccgttt ttcatcaaaa
    22081 aaacgtatct atcaagtgta taggtcatgt agaataaatc tatatactgt agaatcgaaa
    22141 ggagaagaag atgaacaccg gagaaaaaat acgaacttac cgcagaaatt gtaagcttac
    22201 gcaaaaagaa ttaggcgaaa aaattggtgt ttccgataaa acgatttcta gttgggaaaa
    22261 ttctcgtaca atgccagact ttgaaatgct gtcactttta catcatactt taggtctgcc
    22321 gattgatttt ccttctattg aatcagctac cgaatcaata gaaccaacat tgccagatga
    22381 acctcttgtt aacaagaaat cttattcatc aaaacaaccc ttctcactca aaaagacact
    22441 atctttcttt ctgctcgtct tttgtttggt ctatcttttt cttatcaatt atcaatacaa
    22501 aaatgaaacg atcgatcgat tcaatccttt tttgaaacca caaatcggct ataccacact
    22561 ccctgtagga tacgtggaca attccatcga acgttgggta tgtaatgata tctttggcca
    22621 tggtacatgg ctgtcttttc acgctggaga ggtagaaaaa gagaaaaacc atgctgtaat
    22681 caaacacaaa ggaaaacacg tcatgaacgt tcgcctgctc acttgggaag ccattccctc
    22741 agattaccaa gaaatcctca gccaagacta tgacgacgcc ttaaaaagaa gccctcagga
    22801 gccagatagg cattaagtag gagatgaacg tagagataga aaaaatcaat gcacatgatc
    22861 ttatccaaaa aacaggggta caaattaatt gaaaaagcct tgagatgaaa gttcctaaat
    22921 aaaaaagttc agaatgatag gtatttctgg cttatagtat aatatttacg ccacagcctc
    22981 ccaatgattc tttttggaat cataatcaag gatggacatt cacaaaaata ttttgctcat
    23041 tcgatccgaa tagattaacg accaatctag taagtaatat agattggtac gtagtcaagc
    23101 tgcacataat ttagatcaat tttagttctt ttttatattt ctatgatctg ctcatttact
    23161 tttatatgat ggcttacagt aacataaata aatatgataa tcgctggtag tttatccaag
    23221 agtactcaat aaaatacaaa atggattgtt caagcgccta tcataatgat aaaatgaaac
    23281 aaataaacga tacaaggagg aagagacttt gagtaatggc agaacaattt tttcattgta
    23341 aaaattgttc agttgttaat ctatgggatt tcggtagcat gggcattttt ttatagagga
    23401 atcacaccaa cctggccgtt ttatctcttg ttagtgggaa tattagtagg aaattttgcc
    23461 cctcttcact atcgtacgaa cttttttcca actgattctg gcctttttct taaaacaaag
    23521 acgcgaaaat tagaaaacat tattgaaatg acaattacct gtataatcat tttcttagtt
    23581 atattcctaa acgtcttcta ataagaatct cttaaaatta gcttgttaca gttagttacc
    23641 tagtttatat aacacagtta tcttatcttc cttatcaaca tcttttgcca actctttgtc
    23701 ttaaattcga aacatataag cagagctacg aacaccaaga ctgtttcggc tctgtttttt
    23761 gcatcaaatt cactcttata tagctgataa tctcggctct ttaaaagaaa ttattttcgc
    23821 ttcattttat tataaaaagg ctaggaacct tgatgttatc aggttcctag cctttattta
    23881 agtattaccc cacagaccct tccatataga tttttaaatt acacactagt ttaaactaaa
    23941 acaaacaagg aaaaacttac catttaatca aaaaattagc tcatatgaat atattagaat
    24001 gtaaattaga ctggtcaaaa tctggtcaaa aaagaggacg aatacaggta gtcctctttt
    24061 ttgttatttt gatattctaa atcatttttt attggattat tcccttgttc gatatagacc
    24121 caaattgatc tatcaataat tatcaaactg agtcatatag agacaaaaat ttcaaaaatg
    24181 acctgttaaa tggtcatcga atatcattta aaatcaatac gacggagtca gacacggagt
    24241 caaaacaagc ccgctgagag taaaaaatat acagtcccat aggtaaagtg ccacaggact
    24301 gtatattttt ttatttgaga ttacctgaaa tgattccatt taatttttat ctcatttttt
    24361 cctactagtt agtatcaaat actctcctat tttctcaata aactattttg ggttacatgg
    24421 tatctgaaac agctaaaacc ttgtcattat agcaaaaaat cactttatct ccgtttcatt
    24481 tcagatacat ttcacttaag cggattccaa aaaaacaaaa gaaaaaggaa cccctagtta
    24541 gcctatgctt tttattggtt cctctcaaaa cacggtcata taacaacggg gtggggtaaa
    24601 tgaatgaaaa aggtggagga aacattattc aatagctgtc ttaaatactt cgttataaaa
    24661 tgtgaacaaa taaaagacat ctatccctat tttctacact tccacttgac taccatcttt
    24721 gaatcgtaca attttcttaa ctcttctcgt ttacctcaat tcattctcaa gtggaatcaa
    24781 ctcatcatct aacattttac gccatgctcg cttcatttct tgtgggtatt taaatggctt
    24841 cgcttctgga tgtttggctt tatatccttc gtaatcctta ctgttgataa ttgctttcat
    24901 attaggaatt ggatcttcac ctggtagata ttgcagatta gaagcatgta attctttctc
    24961 agaaacaaac cactcattgg aaaagacatg aatcaaatca tcactcgctt gtgtaaaata
    25021 gcgacgttta atgacaaaga tatcttcatt actatctaaa gtccccacat caaatgcatt
    25081 taaaatttgt cggtaaactt ctttgactcc ttctgtttta ttcaatttag ccaaagcttt
    25141 ttcaatttct tctcgtgcat ctgaactatt cgcagcataa gttcctagta attgatcaat
    25201 ataagttgaa tcaatatcat acaacttagt ggtattttca ctataaaatt cgatcgttga
    25261 aaaatcttct ccttcttttt ctggttcttc ctctattaat gaacccttca cggtctcgta
    25321 cacgccaatt tgttcttcca aaagttgaat ttgattgttc aaagttggag atttcaccat
    25381 gtcatcattg taatcgtcat aagtcactaa cgattcataa gcacgattca attcttgaaa
    25441 tgctttgacg tactcgatac ggatttcaag tggcgtatgt tcatcaatgg attccatgga
    25501 tgaaacctct tttaacttac catatgcttg tttgaatctt tttttggatt cctgataact
    25561 tggataaatc aaacctgatt cttcttttgc ttttgaatac agttttgtcg catcctcgac
    25621 attcttctcc attgtcgctg gcttacgaaa cgtcacaatc aatccttttg tcttatcagg
    25681 atacgtacga ttcgtacgtg aaaaagcttg gatcaatcct gcatactcta gattacgatc
    25741 cacaaatagg gtttgaatcg taggggcgtc aaaacctgtt aatagacgat ccactacaat
    25801 cgctaaatcg atttgtttcc caaattgttt gaattccgct ctttttcgtg ccaaacgatt
    25861 attgatgtct ccgttataac gctcaatgtc tgctaatgac caggaagtat cataatactg
    25921 attatattcc tcaataattt tttgcatttc ttcttgttgg gcacttgaat ctcggctatt
    25981 ttcttctaat gaataggtaa tagcgattcg tggaaaatca ggatcctcca tcgttcgtcc
    26041 ttcacgaatg agctgattgg gaaactcttt tgttaaccaa tcaggctctt tcgtcatctc
    26101 tttgatggcc cgataatact ttttggccat gtcaatggaa ctcgtggtta agattgcaga
    26161 tttcgttggc ctgccatttc gaaaatcaaa ttttgtatag gcattatctg gacggaacat
    26221 tttatgaatg actttttgga tatgttcatc tgcttcaaaa acagctgggt ccaaataact
    26281 ttcttttttg acaggttcca tttgatcaat catacgattg atctgttctg atgaatactc
    26341 tgcatatgtt tctacttctt ttaatttccg atagatttta ttctctagtg aagtcggctc
    26401 cacggtgttt tcatgctcta cttgaaatcc taagacagag ccatcttcta gcgcattctt
    26461 aatggtatag gtatgcaaga cctctccata ctgatcatgg gttgtacgtg ccaattgccc
    26521 tttggcttgt ttccgattct caggaaaaat cggtgtacct gtaaagccaa accaagtgga
    26581 tttcggaaac atttttttga tttcttccat attttcagca cttaacgctc gatgacactc
    26641 atctactaca aacacgatat gttggcccat taatttttgg aagcgattgg ttcctttttt
    26701 ctcttcttgt ttctttgcat atttcaacgc cgcatctagt ttttgacggg ttgtaatgat
    26761 tacaacattt gcattggcat ctgccaacag ggtttcactt aattctttgg cacttcccgt
    26821 tccaacgatc aagctattcg ctttggcgtt cccggaagaa atcccagtat taaattccga
    26881 agcaaatttt gtaaactctg tggtggtttg attatctaaa tctttgcggt ccactaacat
    26941 gatcgttcga tcgatccccg attttcgtgc taaaagctta gtagatacaa aactagtcaa
    27001 cgtctttcct gaaccagtcg catgccacac ataccctgat tgatgtttat ttgcggcaat
    27061 aaacaaggct tgaatcgcat gtacttgata aggatgtaac accatgaggg ttttattatc
    27121 ttgatcttca ctgacgattg tataatccgc aatcaaacga tgagcatccg ggatatttaa
    27181 cacttgttta caaaactcat ataagttttc tactttttca ttgtctttcg ttcgccaact
    27241 aaataaaaac ttagggtgca agtctttcgg taaggcattt gcaaaatacc gagtggtttg
    27301 ttcattggaa accacaaaca actgtaaggt cgaaaagata ttgttccgaa acataccttc
    27361 ttctgcatat tttttgattt ggttaaatgc ctgataaaca ccatcttttg cagttacttg
    27421 tttcagctcg atttggacaa tcggtaatcc attgattaat aaggtgacgt caaaacgtcg
    27481 atcccgtgct tctatgttac ttccacgttt tgcaatttga tggaccactt cataagtaga
    27541 gattcctcca ccaatgtctt gattggaata aaggataagt gagacagaac ccaattgcga
    27601 atcttcccgt tcaatcgtga tccgagccat cccattttca ccttttaacc atttcgcagc
    27661 atcaaatggg gttttcgttc gcagcagtaa ttccgttttg atcgtttcaa attctttatc
    27721 ggtcaaagga aaatcattca gttctgcttg attatttgag ataatttttt ggcgtaaatt
    27781 gacccaaagg tcttcttctg attttagatc cggacgatac gtccactgat tatgcccttc
    27841 tccaagtaca cgaatcaact gttcttcgac ttctgcttcc tcacggtgac taattttcat
    27901 tcttcttccc tcctagacaa acatcttttg taagaagctt tttttcgttt cttttagtaa
    27961 atctaactta cgttgatgaa gagcgatcgt atcatctagc tgtttgaaga aagtaccgat
    28021 tttttgttgt tcatccttta caggaacctt aacactgata ttctcaatat cagaactgtt
    28081 ataagaaggc aatgccccta cttgggagta tcttggcaaa tttatagttt caaacaatat
    28141 tttaccaaaa tagatatccc aagtattatt aaataaataa gccatggtat tgttatctat
    28201 taagaaaggg cttgtgacca aacgttttct attaagcatt attgctgcgc caactttagc
    28261 aaatataatc gctggcacat cttttattgg cttccatttt ttacgctcaa tttgctcatt
    28321 agatacataa tgatttgcat ttctcatttc atactcatta ccaatgttat tcatgtcgga
    28381 aactttaaaa aatggagtac cttcagaacc accttgctcg gcatcaggaa atccaattcc
    28441 cgattgagtt ttacctaatt ctcccaactt acgctcttcc caatcttccg taaaaccagg
    28501 aaaccggatt tctggcactt ttgctccgtt ttcagggaac attttttgta agaatccttt
    28561 tttcgtttcc ttcagcaaat ctaacttacg ttgatgaaga gcgatagtgt cgtcgagttt
    28621 tttgaagaat atgccgattt tttgttgttc ttttaaatca ttgggaatat agaatactgt
    28681 atctgaaact tttttccagt ctgaacgagg catttttgtt ccagatgtat catttgcagc
    28741 cttttgatat ctatcagctt gaataagaga ataaataaag tccgagtcgc tcttcttagc
    28801 tctaaaaacc cagaaatccc caatcgctac gcctgtaaaa gttgccttga gccaattttt
    28861 taaatatgga cgtaactttc catatagaat atcatttggt aaaaattcaa tcccttttct
    28921 attatcaaat ttctggctca catctttatt cagtctacct tctcctgcca cgatatcttc
    28981 aaattcaact tttggaagtc tactggagtt tgtactttta ttaagtctaa caactaaatc
    29041 aattaactta cgctcttccc aatcttccgt aaatcctggg aaacggattt ctggtcgtgt
    29101 atcattgctc atgtttgaac acctccagcg caccttgtaa ccacatttcg ttttcaggtg
    29161 ttgtttgcag ggaagagata gcttctaaaa gttctttttc tagcacttgc tgttcttgtc
    29221 gtatcttctt gatgtcattt ccgacatgaa ccatatcaat tggttcttct tcttcgaaag
    29281 tatctacata gcgtgggata tttaagttat agtcattttc tttgatttca tcaaaggttg
    29341 ccaaatgagc gtatttctcg acatcttttc tttcagcgta ggtttcgagg attttttgaa
    29401 tgttttcttc cgatagttta ttttgatttt tccctttaac aaattcacga ctagcatcaa
    29461 tgaataatac atctcgagtt tgacgattct tcttcaacac aatcaccgtc gttggaatcg
    29521 atgtcccaaa gaacaagttc gcaggcatac cgatcacagc ataaatactg ccatcttcta
    29581 gtaatttttg acggatgacc ccttctgcag cgccacggaa taaaactccg tgtggtaaga
    29641 cgatggccat ggtacctgtt tccttcaaat gatagaaccc atgaagaaga aacgcaaaat
    29701 ctgctttgga ttttggcgct aatttcccat aacgattaaa ccgagaatca tctaagaaag
    29761 tcgtatctgc tgaccaatta gccgaataag gtgggttcat tactactgca tcaaatgtgt
    29821 aaggttcatc tgttggccag tccttattca acgtatcccc attgcggaga ttcatttctt
    29881 cggcgtcgac accatgtaaa atcaagttca tttttgctag attgtatgtc gttgtattta
    29941 gttcttgccc atgatattta acgttatctg ggtgtgttaa gtagttacgt acgtttaaca
    30001 tcaatgaacc tgaacccatc gttggatcaa aaacactaaa gaatcgtcgt tccttttgat
    30061 cgagcgttac gatttgcgcc atcatatcag aaaccatatg aggtgtgtaa aattctccgg
    30121 ctttcttccc tgcttctgaa gcaaattgac tgatcagaaa ctcatacgca tccccgatca
    30181 cgtccccatc gtgttctaaa acatctacat cattcaattt cttgatgact tcggtaatcg
    30241 tcacatttcg ttgttgctca tctgttccta gtttttttga ttggagatcc acatcatcaa
    30301 ataacccatt aaattgattg taggtagatg ccaattgcac aaaggctttg tttagatcgt
    30361 tcaattggaa cgttgcttgt tttgcttgat ccgctaagac gttgaaaaga tactctggtg
    30421 caattgcata tcccaaaata tcaacgattg tggcaatcag atcttctttt gattcttcat
    30481 ctgaaagtaa ttcacgatac aacattgttt gtttgcttac tgtgtcatat tcctctaagg
    30541 attcatctgc taaaagaacc acttgttcca acaatcgatc ggataaatat ttatagaaaa
    30601 tcagtcccaa taaataattt ttatattctg acgcatccat tttactacgg agattatctg
    30661 ccgcactaaa taatttttga tttaattctg cacccaaaaa gatacactcc tatctcttat
    30721 ttaaagttgc tatataccct cttattttag cataccccct tttataaaaa gcaaaaaaaa
    30781 aagaaagaaa cttattcttg ctaataaact acgcgaaagg agtctaacgt tgtttgatat
    30841 aacttagact gatcgttaac ttatttttta tatttctaca tagttatctt tagaaccatt
    30901 tcagatacat atgaaacaat tacatatgat tttttcataa
//
LOCUS       DADVXM010000025        29142 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.026, whole genome shotgun sequence.
ACCESSION   DADVXM010000025 DADVXM010000000
VERSION     DADVXM010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29142
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.026"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(47..1342)
                     /gene="purB"
                     /locus_tag="KB927_001231"
     CDS             complement(47..1342)
                     /gene="purB"
                     /locus_tag="KB927_001231"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBB6840160.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVILWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1355..2479)
                     /gene="purK"
                     /locus_tag="KB927_001232"
     CDS             complement(1355..2479)
                     /gene="purK"
                     /locus_tag="KB927_001232"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBB6840161.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2472..2960)
                     /gene="purE"
                     /locus_tag="KB927_001233"
     CDS             complement(2472..2960)
                     /gene="purE"
                     /locus_tag="KB927_001233"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBB6840162.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3376..4683)
                     /locus_tag="KB927_001234"
     CDS             complement(3376..4683)
                     /locus_tag="KB927_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBB6840163.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4686..5267)
                     /locus_tag="KB927_001235"
     CDS             complement(4686..5267)
                     /locus_tag="KB927_001235"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBB6840164.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5383..5480)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5839..7131)
                     /locus_tag="KB927_001236"
     CDS             complement(5839..7131)
                     /locus_tag="KB927_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6840165.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7128..7751)
                     /locus_tag="KB927_001237"
     CDS             complement(7128..7751)
                     /locus_tag="KB927_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840166.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7754..8590)
                     /locus_tag="KB927_001238"
     CDS             complement(7754..8590)
                     /locus_tag="KB927_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6840167.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8607..9494)
                     /locus_tag="KB927_001239"
     CDS             complement(8607..9494)
                     /locus_tag="KB927_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6840168.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9510..10793)
                     /locus_tag="KB927_001240"
     CDS             complement(9510..10793)
                     /locus_tag="KB927_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6840169.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11476..12159)
                     /locus_tag="KB927_001241"
     CDS             complement(11476..12159)
                     /locus_tag="KB927_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBB6840170.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12177..12794)
                     /locus_tag="KB927_001242"
     CDS             complement(12177..12794)
                     /locus_tag="KB927_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBB6840171.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12804..13628)
                     /locus_tag="KB927_001243"
     CDS             complement(12804..13628)
                     /locus_tag="KB927_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBB6840172.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13621..14181)
                     /locus_tag="KB927_001244"
     CDS             complement(13621..14181)
                     /locus_tag="KB927_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840173.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14355..15311
                     /locus_tag="KB927_001245"
     CDS             14355..15311
                     /locus_tag="KB927_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6840174.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15616..16572)
                     /locus_tag="KB927_001246"
     CDS             complement(15616..16572)
                     /locus_tag="KB927_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBB6840175.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16676..17278
                     /locus_tag="KB927_001247"
     CDS             16676..17278
                     /locus_tag="KB927_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6840176.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17366..18865)
                     /locus_tag="KB927_001248"
     CDS             complement(17366..18865)
                     /locus_tag="KB927_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBB6840177.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18881..19405)
                     /locus_tag="KB927_001249"
     CDS             complement(18881..19405)
                     /locus_tag="KB927_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBB6840178.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19703..20452
                     /locus_tag="KB927_001250"
     CDS             19703..20452
                     /locus_tag="KB927_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6840179.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20443..21228
                     /locus_tag="KB927_001251"
     CDS             20443..21228
                     /locus_tag="KB927_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBB6840180.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21197..21913
                     /locus_tag="KB927_001252"
     CDS             21197..21913
                     /locus_tag="KB927_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6840181.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22015..23049)
                     /locus_tag="KB927_001253"
     CDS             complement(22015..23049)
                     /locus_tag="KB927_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBB6840182.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23053..24111)
                     /locus_tag="KB927_001254"
     CDS             complement(23053..24111)
                     /locus_tag="KB927_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBB6840183.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            complement(24333..25481)
                     /gene="nagA"
                     /locus_tag="KB927_001255"
     CDS             complement(24333..25481)
                     /gene="nagA"
                     /locus_tag="KB927_001255"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBB6840184.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(25557..26393)
                     /locus_tag="KB927_001256"
     CDS             complement(25557..26393)
                     /locus_tag="KB927_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6840185.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(26577..27794)
                     /locus_tag="KB927_001257"
     CDS             complement(26577..27794)
                     /locus_tag="KB927_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6840186.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(27943..28122)
                     /locus_tag="KB927_001258"
     CDS             complement(27943..28122)
                     /locus_tag="KB927_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840187.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            28177..28260
                     /locus_tag="KB927_001259"
     tRNA            28177..28260
                     /locus_tag="KB927_001259"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28211..28213,aa:Leu,seq:gag)
     gene            complement(28500..29078)
                     /locus_tag="KB927_001260"
     CDS             complement(28500..29078)
                     /locus_tag="KB927_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840188.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         8687 a         6234 c         5008 g         9213 t
ORIGIN      
        1 tatttttgct attctatttt aattgaattt tgcaactcac tcttctttat tccaaaccta
       61 ctcgtttgaa tatcacgtca acgtttttca aatgatgatg ataatcaaag gcatcgtcta
      121 tttcttcttt agataatacc gatgtgatgg ttggatcttc ttctaacagc gggcggaact
      181 gcacttggtt gtcccaagcg tacgcagttt ttggctgaac aagatcataa gcttcttctc
      241 ttgtcattcc cttatcgatc aatttcagca taacgcgctg gctataaatc aaaccaaatg
      301 ttgcagacat attccgcttc atgttttcag gaaagaccgt tagattttta acgatattgc
      361 caaaacgatt taacatgtaa ttcaataaaa tcgtggtatc aggcaagatg attcgttctg
      421 ctgaagaatg agaaatatct ctttcatgcc ataatatgac attttcatag gcagtgacca
      481 tgtgtccgcg caccactctg gctagaccag ccatattttc tgaaccgatc ggattccttt
      541 tgtgcggcat agcagaagaa cctttttgac ctttcgcaaa aaattcttct acttcacgtg
      601 tttcggattt ttgcaatccg cgtatctctg ttgcaaaacg ttcaatactt gtagcaataa
      661 gcgccatcgc tgagaaatat tcagcatgta gatcccgagg gagaacttga gtagagattt
      721 cttgtggacg gatccccaat tgtttacata catactcttc aataaatggc gggatatttg
      781 cgaacgttcc cactgctcct gagatttttc ctgcttctac tccttttgcc gcatgttcaa
      841 atcgttcgat gttccgtttc atttctgaat accatgtggc aagtttcaat ccaaaagtag
      901 ttggttcagc atggacaccg tgtgtccgac ccatcatcac tgtatatttg tgttcttttg
      961 ctttttcgcc aatgatttcc gtaaaacgtt tcaagtcttc ccgtaaaata tcatttgctt
     1021 gcttgatgag atagccataa gcagtatcta cgacatccgt acttgttaga ccataatgga
     1081 cccattttct ttcttctccc aatgtttcag aaaccgctcg tgtaaacgca acgacatcat
     1141 ggcgtgttaa tttttcgatt tccaagatcc gatcgatatc aaatgatgca tgctcacgaa
     1201 tttttttcac atcttcttgc gggatttcac caagttctgc ccaagcttca tctgctaaaa
     1261 tctcgacttc gagccacgca cggtatttgt tctcttccgt ccagatattc cccatttcag
     1321 ggcgtgtata acgttctaac atgttttttc tcctctaatc ccaaatattc gtttgtttga
     1381 tttcttccag cgtttgctgg atgtcttctg tcaagatagt gatatgtccc atcttgcgac
     1441 ctttttttgc ttgttttttt ccatagaaat ggaattgcca gtctggctta ttctcaatca
     1501 agcgatagct ttccagcagt tgttctccca aaacattgac cattactgca ttgcttatca
     1561 aacgtacttt ttctcctaat ggccaaccac aaatacctcg aatatgggca tcgaactgac
     1621 tcatagaaca agcttcaata gaataatgtc cagaattgtg aggacgagga gctaattcat
     1681 tcacatatag cccgcctgtt tttgttaaaa acatttctac ccctaaaaca cctgaaaggc
     1741 tcactgcttc tgcaatcaca cgggcaatac gctcagcctc ctcgatcaca tcctgatcaa
     1801 tcgcggctgg agcaatcgtt tcatgaagaa tattgttgtg gtggatgttt tccacgaccg
     1861 gaaaagtcgt gaaatctcct tgaccatttc ctgccaccat gatcgaaatc tctttttcaa
     1921 acgggatcca tgcttctaaa acacaggttc cttctcttaa aaggtccatg gcaggagcta
     1981 gatccgcccg acttttcaaa acatactgcc ccttgccatc atagccgcct cgagtggttt
     2041 tcaaaacaca aggatagccg atcccgtcaa tcgcatcttg gatatccgtc ggactgacga
     2101 tcgttgcata aggagcaatc acgatgttat tcgtttccaa aaaagatttt tctaacaggc
     2161 ggtcttgcgt aatcgcaagc aagtctgtcc cttgaggaat aaatgacatg ggtaaaatcg
     2221 catttaacgc ctctacactg acgttttcga attcataggt aatgacatct gttcttctgg
     2281 caagctcttt cagcgcaaag gtgtcatcat agacactttc aatgtgccaa tctgcaactt
     2341 gtgcggctgg acaatcgctc acaggatcca gcacacctac tttaaagccc atttcttttg
     2401 cactaatcgc catcatacga cctaattgac cgccaccgac gatcccgatc gttgaaccag
     2461 gcaacaaagg tttaaccaag ttgatcacta ctttctataa cagttttagc caacattgaa
     2521 cgtctttcag ccaatttagc ctccaattct aaatcataca tggaaagcat ctgtatcgca
     2581 agtagtccag cattaattgc tcccgctttt ccgattgctg tagtagctac aggtactcct
     2641 ccaggcattt ggacaatcga aagaagcgaa tccaaaccat ttaatgttcg tgattggacc
     2701 ggtacaccga taaccggcaa agttgttttt gatgcgacca tacccggcag atgcgcggct
     2761 ccccctgctc ctgcaataat gattttgatt cctttttttc gagcgttttg tgcatattca
     2821 aacatcaaat ctggggttcg atgagcagaa acgacctttt tttcataaga cacaccgaat
     2881 tcatccaata tttgacatgc ttctttcatt gtttcccaat ctgaagtact ccccataatc
     2941 acagagattt ttgctgtcat tgtttttcct cccagttttt ctacattcat attttaacaa
     3001 tcactttttt tgatgtcaaa gaaatttcga atgttaacaa agaaaaacat tttattgttc
     3061 gtgtttatta aagataaaaa aaaggaatgt gacaaaagtt aggtcacatt cctttttatg
     3121 gataaacggt gttctcctgc caactcctcg gtcacaagga acaatattca acaaacatga
     3181 gaagcttttt tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc
     3241 ttccttcaac ggtgttcaat cagctgaccc tcggtattag ctcaaacaaa cggcaaaata
     3301 cgaggaacta tttttccgtt tgtttctcta acaatcaggt caaaacgctg atttcacaac
     3361 ctttcttttg ctctattact tcttgaaggc ttcttccaat atttcttcat cttttttcaa
     3421 tccattaaag atcaaattca atatgatagc cgtaatgcta ctcattacga tgccatttcc
     3481 agtgaacatt tgcaatgttt gcggcatttg actgaataat gtcggcgtaa cattgaaacc
     3541 cagcccaaat ccaacagaaa cagcaacaat caatagattt ttatcattgc tgaaatcaac
     3601 ttccaacagc atacggattc cttggactgc caccatcccg aacatgacta acattcctcc
     3661 accaagtacc ggctcaggga tgatttgtgc taacgcaccg attttaggga ataatcctaa
     3721 aacaatcaag aagaatgcag agaaatagat gggttttctt gttttgattc ccgaaagttg
     3781 aaccaatccg acattttgag aaaagccagt ataagggaat gtattgaaaa taccgcctaa
     3841 gataacggca agtccttctg cacgatatcc ctttttcaat tcttcttctc caacattttt
     3901 cccagtaatg tcaccaagtg caaaatatac acctgttgat tctaccatgc tgaccatgga
     3961 aatgatgatc attagtaaaa tcgaccatac gtcgaaagtt ggtttaccaa aataaaaggg
     4021 ttgtggaaca tggaacaacg gcgcatctcc aatcgcgctc agatcaatca ttcccatgaa
     4081 agcagctaag atgcttcctc cgactaaacc aatcaatacc gcgattgaac gaatgaaccc
     4141 ttttgccagc atttgcacgc ctacaattag gagaatcgtc acaaatgcaa gtagcagatt
     4201 tgttttgtca ccaaaatcag ctgctgttgc attacctcca cccattttct cgattgctac
     4261 aggaatcaaa gtcaaaccaa taacggtgat aaccgttcct gttactatag gagggaatag
     4321 ttttttaatt ttagaaaaga caccagaaac taacacaaca aagatcccag aagcgataat
     4381 agatccgtag atagctccta ctccttcatt ggttccgatc aagatcagtg gagctactgc
     4441 ttggatcgca catcctaaaa cgacaggcaa gccaattccg aaaaatcggt taactgtcaa
     4501 ttgcaataat gtcgctaatc cacacataaa gatatcaatt gaaatcaaat aagtcatctg
     4561 ttcttgatta aagcctagtc ctgtaccgat caaaagaggc accgctactg ctcctgcata
     4621 catcgctagc agatgctgca gccctaaaac cgcagctttt ccattttgtg tttctttttc
     4681 cacgattatg cgtcctcctc aagaaactca acttgtccat tcgtcaagga agcaatacgc
     4741 gcaagagaaa cgactctcaa tcccatttct tcaagtaact gacgtccatc ttggaaagac
     4801 ttttcgatga cgatcccgat tccttctact tgcgctccag cttgctggca taattcgatc
     4861 aatccttttg ccgcttgtcc gtttgccaag aaatcgtcga taatcaatac tttgtcttct
     4921 gaagataaaa atttacgaga aatagaaatc gtacttgtca cttgtttcgt aaaagaataa
     4981 acagaagctg tcaataattc ttcatccatc gtcaaacttt ttgcttttct agcgaagatc
     5041 attggaacat ctaattctct tgcagcaaat aaagctggtg cgatcccaga agcttcaatg
     5101 gtcacaactt tcgtgattcc ttgttcttta aatacttctg caaaccgttt tcccatttgt
     5161 tccatcaata cagggtctac ttggtgagtg acgaagctgt cgacttttaa tacgccctcg
     5221 cctaatatac gtccgtcttt ttgaatacgt tcaactaatt ctttcacttt atttgctcct
     5281 ttatcattta ttaataccga aataaccgct tttgtgcaaa aacctactat gtttctgtta
     5341 aagaaaaaca ccctccactt tatcataaga aaagaagggt gaaatagcca atcttttact
     5401 tatagtccag catttacggt actggctaga aactgtcatc catattatga cgatatataa
     5461 gtaggtatgt aaaactaata atagtgtaaa ttcattttct tgcaactgtt ttgcacgtga
     5521 aggcagtttg ccatatttga ataaaaaatg ttgtttcaaa tattgaaaac agtctaacac
     5581 tactttctga aactgacaac gtggtttact tatttttttg taaaatctaa tgatttttaa
     5641 tgcattattc ctttttgttc gggtttaaat agttattttt attttctcct atctaaaaaa
     5701 gcagcccaca taaaaagaag gcatgacaaa aagcatgtca tagccccttt ttccgaataa
     5761 atagtgttca aaagacagcc tatcggcaat aaggcaagat tttataaact acgggaagta
     5821 atttccgtaa atctattctt attcttttaa gctgacaagc tcgtcaatca ctactgcttt
     5881 tcctgaagca atagaatgat ttgctgcgat tcctgtcaaa atcgacaaaa taccatctac
     5941 gtgagttgct gcccgattcc acggatcttc ttctttttct tcaccaaata gatcatctaa
     6001 taaacgcgga tctcctccgc catgtccgcc cgcttcttgt tcgacgatta cctcatatgg
     6061 ctcaccgaac atcggataga catggatgga ctgaagaacg gctgctcctt catccttttt
     6121 atctccacct gcattgatgt aagacttttc gatcactttc atttcgatcc gtcctttgct
     6181 gccattgaaa gaaacattga atccttccca cggcatatac gcgtttagcg aatacgtcaa
     6241 aatcgcacca gtttcatatt tgaccgttac gcctagtgta tcttcaatag agatatcatc
     6301 ggaaaataca ctgcggtcac gaatatatcc actgtctttt tctgcttcta aatacatttc
     6361 tcgcaattcc tcattggctg acaggtctat agcaaatgga tcagctttag ctagttcgct
     6421 tccatagcat cgactgtaaa atatttctac tccgcgtttc tccgcattat gcatcccata
     6481 aaagtttaat ccaccgaatg caaatacctt ttggggacgg ctgttcaacc aaaaattcac
     6541 tagatcaaaa tgatgggtag atttatgaac aagaagcccg ccgctattgt gcttatttcg
     6601 atgccatctt ctgaaataat ctgccccgtg ttgcgtattt aacagccatt cgaagtggat
     6661 agaaaacaca tcaccaatca catcactttc tatcagttcc tttatcttcg tgtgatacgg
     6721 tgcataacga taattaaaag tgactcgcag gcttcttccc gtctgttttt ggaccgttat
     6781 tatttcttga gctttttcct catcgatagt cagaggtttt tcgcaaataa catcatatcc
     6841 ttttttcatt gcacgaatga tataatcatg atgcgttcga tctactgacg taataatgac
     6901 ttcagccggc cgtacgtcat ccagtagttg ctcaaattgt gatggcatac atgtctttac
     6961 ttttttctgt ccatacttgt tcacaagtat ccgatttgca taatccatcc ttgtttgaga
     7021 tacatcacaa aaaccgacta gttcacaagt ttgatgatac gtagaggcaa ttgcctcata
     7081 aaaaaaacgc gctctcccac caagtccgac ttgtacatat tttttcttca tttaaagtca
     7141 ttctcctttt cttttaagca aaatactgtg acaaatggca gccctggata cagtaatgca
     7201 gtgagtaaaa aatcatgctg tatacaccag aacagtccat acaaaaggca taaataccac
     7261 agaaacccct tgacgttttt tgacaacagc cagatattcc ttttgatcaa ataaacaaga
     7321 ctatctgctt tatcttcttt gcagatatca attagcgtac taaaaaaact atgggataca
     7381 aaaagcaaca gacacaatag aaaaggaatc agataccaag ctccaatctt tcccactaat
     7441 aaataccaat caactgcaaa aataatgaca aacagctgaa acaacgtaat gatgaaacac
     7501 atccgtttga tttttccttt cctccaacat accttttttt ctgccaagta atggacagat
     7561 agataataag aaggatacat catcaaaaaa taaatcagat agacaacacg agcagacagc
     7621 actaatccta aagtgaacaa acatcctaga actaaagcga aaagagcatt actgataaga
     7681 ctggttaaaa aaatccgaca gacatagtag ttgagcttgt aaagaaacat ctcttctatt
     7741 ggctttttca tattcagccc ttcagaccgc ttgtactgat cccctggaca agatatttat
     7801 tgaagaataa gaaaatcaga aaaaccggta gcagcgacaa cgtagacatc gcaaacatac
     7861 tcgcgtaagt cgtactagat ccagcgtctg caaataattt gatggcaatc gataccgtgt
     7921 aagatctcgg cttgtttaaa taaatcaatg gtcccatgaa gtcgtcccat ttccaataaa
     7981 actggatgat gatcgtcgtg atgatcgaag gtttcagcaa aggaaaaata attttggtaa
     8041 agacactata cttgctgcat ccgtcaataa tcgctgattc atctaactct ttggggatgc
     8101 tgaccatgaa ttgcatgatc tggtaaatga aaaatgcttg tccaaaaaaa tgtggtaaaa
     8161 tcagcggcac atacgtccca accaaattca gccgattgta aataataaac tgcggaatca
     8221 aaatcacttg tgcaggaatc atcatcgtta ctaacatgac gacgaaccag aatctttttc
     8281 ctttgaaatc gattctcgat aatgcgtaag caatacaagt cgagctcaga actgtcccta
     8341 tcgtcgaaac tgcagagatg acaaacgaat tcctaaagaa agtaaaaaat gaaattccag
     8401 caaaccccgc ccatcctttt gcgtaatttt cccattgaaa agtctctgga atcaaattca
     8461 gcgaaccact cataatctct tgatccgttt taaaagaacc tgcgatcatc cataagaccg
     8521 gataaatcat gactagacct aatagcaaaa taaaaccgta ttgaaaccat ttcgttactg
     8581 tattattcat ttcttcctcc tctcattcac acaacgaccc atttttttga tgatttgaaa
     8641 atcagaaagg tgacagctcc cataatcaac agcatgatcc acgaaatagc actagcatac
     8701 cccatagaat taaaagaaaa agcttggtta tacacataaa gagcataaaa gttcgtggca
     8761 tcattcggac caccttgggt aatgataaat gcctgcgtaa aagtcataaa cgccgcgatt
     8821 gtctgcataa ccaagttata caaaatgatc ggcgaaagaa gaggtaacgt gatcttgtaa
     8881 aacgtctgcc atttgttcgc tccatcgatc tctgccgctt cataatacga gcctgggatc
     8941 tctttgatac ctgcagcaaa gatgatcatt gccgaaccga attgccaagc agacatcaaa
     9001 acaagaggga tcatgaccag tttttgatcg ctaaaccagg aaagcgcagg tgcgcctaat
     9061 cgttccagga aaatattcac taacccgttt ttagaaaaca actcccgcca aactagagcg
     9121 atagaaatac tgccaccgat caaactaggc acataataca aagaacgaaa gaaagtcgtt
     9181 cctttgatat tcctcgttaa aagataagca atcaatagac caaagatcag tttcacaggt
     9241 acagatgcaa atacatagag aaaagtgact cggatggagt tcaaaaaacg ggcatcactc
     9301 agcatcttta tataattatc caagccgatc catgagactg gatttcccaa acgataatcg
     9361 gtgaacgaat aataaagtga caagatcatc ggtatcactg ttatcaatag aaatcctagg
     9421 atgaatggag aagcaaatac gtaaccgacc acattgtctt gatccaagaa ccgttttagt
     9481 ttttcttttt tcatgccttc ctcctgctgc tatcctagaa tgtttgacgc aaactcataa
     9541 agactctctg ctgcttcttc tgctgttact tcttcataaa tgactttttc aactaaaaga
     9601 ttgtattggt cttgaatttc cggattcaaa gcactatcaa agacattcac ttcgccgttg
     9661 tccatatcgg aaatcatttc taaataatca aatgtcgctt gcaaagttgc atcatctgca
     9721 cgagcgagct gttctcgaat attcgacatg attggtacac cacgttctcc ttttaaaatt
     9781 tcattggctt cttcactgtt ttgaaagaaa tcaataaact tagcagcttc ttctttatgg
     9841 gctgagcttt ttgccatact cagcatttgc gaagaacgta aagggatacc agattctcca
     9901 tctgcttttc tgcgaggtgg attaatcaac tgaatctcca tatcttcagg agcccctgac
     9961 aatatttctg tcaactggtt acttgataga aacaccattg ccgcttctct atccctaacc
    10021 gcctgaaaag acagatccgt cgtacttgca gctccaccac ctggttctgg atgggcccct
    10081 ttgtctacca gatttttacg cagctggaaa aaatctgtta gatagtctgg attttcaaat
    10141 cccaagctgt tagatagatc ttcccgatta taaaaattca atcctttctc aacttgtggt
    10201 atttgaataa tacagccagc tataaaatct tcgaatcttg aaatagcata gattcctaat
    10261 tcttcagtga tttgatagct gatttgttca aattcatccc atgtccaatt tgaagctggt
    10321 tcagggatat ttaattgttc aaatatattt ttattgtaag caatcgcaaa cgaattcacc
    10381 ccgttagaca gtccaactaa ttgcccgtcg taagtcgtcg ttgctaaata ggattcatct
    10441 gcattagaaa tatcaattat cccttgctcc acatattcat ctaatggttc aatctgattg
    10501 atgtattgag gaaattgatt gttcagttgg aaaatgtccc agatatcatc tgatgctgct
    10561 agtgtaccta attttgtgta atatccttca taatcataaa attcataatc gatcgtcaca
    10621 tggggatttt tttcttcata aagctcgatt acttttactg ttgcatcgtg tcggacttgc
    10681 gaaccccacc aagccatgtt cagcgtgatt tttttgtcat cttcttgccc acaagccgtc
    10741 aagaagaata acataacact taaagctaag atgattctca ttcttttctt cattctctgc
    10801 acctctactt ccattgttat ttttcaatat actgtatttt tatacagaac atatttatta
    10861 aacgatcttt ttcaagggga ataaaaacca agacttgcct tatcgttctg cctaggatga
    10921 acaactcaat actttcaaga aaaattagat agtgctgatt cttctttcat cgctaaaaac
    10981 acttcttgct tcaatgatgg gaggataatt acgcaaagaa aaaaggatat cagacaactg
    11041 cccaatatcc ttgacatagc taaataagca tgcttcttcg tgtgcgctct tccctaaaaa
    11101 acagaaaaat aactagtaat tctgtatgaa attaggtaca atatacacgt cgatgcacaa
    11161 gcattgacta tggcaacttg attggtcagt tcccgctgac ttttcaagcc ccgacaattt
    11221 agctgctact aaattgtcgg gtgccttttt tagtttttat tcgtttttca ttctatagaa
    11281 agcgcttcaa taaatcaaga catttttttg ttagaatgct aataataaca aaaggtttta
    11341 actcttctta tgtacattac aggtaaaaaa acaaaaaaat ttctcttttt tttgaattct
    11401 gaacaaatag tactggagta caaaagacga ggaagagcca ctatctgctc ttcctcgtct
    11461 tttgattctc acctgttatt catgattctt tttctcagtt tcccgatatt tttccatttt
    11521 acgactaaaa agctctccgc tacttggtgg cgtatatgtg atggcatttg ctcctgcttg
    11581 aatggtctca gcaatacttt cttccgttgg accacctgtc gcaatgatag gaagttcagg
    11641 atatttttta cgaaaatggc gtactgcttc tgcagtttct ttacctgcac tgatattgat
    11701 aatcgaaata ccagctgcta acttttcatc tatttctgta tatttcgacg ttaccgtact
    11761 gataactgga atatcaacta ctcgacaaac ttcttttact gtctctaaag gcgtaggacc
    11821 gttcaaaacg acccctaacg aaccttgcgc ttctgcgaac atgctcatgt aggaagaacg
    11881 agcaccttgt gtcaaaccac cacctacacc ggagaaaact ggaatgtcag ctgcctcaat
    11941 aatgctttta gtaatcgctg gatgaggtgt aaaaggatac acagcaatta ctgcattcgc
    12001 atttgtatta cgtatgatcg caatatccgt agtaaagatg atcgaacgga tcaattttcc
    12061 aaatatcttg atcccgcttg cttctaaaat gatttccggt actcttacga tatcttttct
    12121 caattccgtc atgatttctg gcgtaaattg ttctgccatc agccacttct cctttgctat
    12181 ctccggtcat actgattcaa ttgatacgtc tcgatgacct ggatgatttt ttgcgcataa
    12241 ccggggtctg tcgcataacc tgcatcttgc aatgcttgtg cggcttcctg atagttggtg
    12301 gccgtaatca ctttttcata cagcgcagga ttccaatcta ctccttggac gaacagttgt
    12361 gtatggtcat ccatggactg ttcccatgaa tcatacactt tgaagtctcc ttggatagtt
    12421 atccattctt cgttaacaaa ttcctttgtt tccaggctta ctttcttctg atccccataa
    12481 gccttgatcc cgaaaagatt attgtatttg ctagccaagg tactttttcc ccaatttgat
    12541 tctaatatag cttgtcctaa aatgatacta ggaagcactc cataaccatc ttgtagttct
    12601 tgggcatgcg gaacaagccg ttcaataaat tgctgatggg attgcgcttc attttcttgc
    12661 tgattatcag taaaaggaga agacagattc ttcaaggaaa aaacaaaggc taagagtatc
    12721 actgctacac cggcaaccac tgctggccaa cggatattct tgcgcttttg ctttttccac
    12781 ttttttttcg ccatgatcaa ttcctacttt tcatttaatt cattcagata ttcttctagc
    12841 gtcaattggt gtttggtgat atactcagcg ttttctttac cgacataacg taagtgccaa
    12901 ggttcatatg tgatcttagt tatatcttcg tgtccttttg gataacgaac gataaatcca
    12961 tactgcgcag cattatctgc gatccattta gctccaggct gatctccgta acttgcatcc
    13021 aatacagtag aaggataact gttgtaccag ttttgatcga cgacatcgac tgccagacct
    13081 gtgtggtgtt cgctgtatcc tggctccgta atcgtttctt tagtaatctt tgtcgcctcc
    13141 tcttctgata caccttgacg actcatcaca tcttggacat tttgttcgaa aacttgttgt
    13201 tgggatgata cagaccggta agctgagacc atcactaatg gaaatccagc tgcttcagca
    13261 gccttggcaa atgcttcata ttctggagca atgcgtttgt cgatcaagta tccgttactt
    13321 aatgatgcca attgagtaga ctcatcaatt tctttttcta atttgtgatc tggaccaacc
    13381 aaaactagct tccaatcgtc tgttttaaca tctggcaatt gtttggacgt acgatctttt
    13441 gtttctttgt cctttacctt gctgctggtt gtttgactgt tcttttcttt actagcagtt
    13501 gttttggtgc ttgttcgttc gactgcttga ttgccggctt gaacatgcga atcatcatcg
    13561 ctaaaaataa catagcccat tgctgcgatc ataatcacaa ctgctccaaa tcctaaaaat
    13621 ttattcactt gaaaaatcct ttcgttgttc ttcacgttcc ccattcgcct catgaacgta
    13681 agtttcttcc agattttcat tcacccaatc gagaagttcg attttttctc cttcgatctg
    13741 tttttgaaca tctgctggca gacgaaaatt caaaatatca tcatagcccc attcatcata
    13801 ttgaatactt actttcaagt caaggtatct accagcctgc tgattatttt tcaaagggat
    13861 cagctcgact tttgctgctt tgctgctaag ccatttttgc gcgatgcgtg ttttgatttg
    13921 cttgtactct gcaacggcaa cgtttcgttt ttcgggaaaa ataatcgttt gacgcaaaat
    13981 cttttgcgtt agcatccatt cataatcagt gaaaagattt tttactttct gcatcgcttc
    14041 agatggcaga tttttctcgc catctttcca tttttgccat tgttctggac tgatcagcaa
    14101 gtattcatct aaaaaatttt tttcagtttc aaactgttct aataatacac tcataataag
    14161 atcaatatat acttgatgca cgtttatccc ctccttttaa ctattctact taagttttga
    14221 tcaaaaagca cctcttaaat cgctgctttc atttttttta atgtttcaag tcctctcctc
    14281 tttattcttc gtgatttttg ttataataat agacagacaa gaaactcaat ccaactatga
    14341 aggagcgttt tcagatgaaa aaatatcaat ggggaatcgt tggtcttggt accatcgcac
    14401 atgagtttgc cgaaagcttc aatcaagaga cgagcgaact aacagcagtt gcttccagaa
    14461 cttcagaaaa agcggaaaac ttcgctcacc gttacaatat tccaaaagct tacggaagct
    14521 atcaagaaat gttagacgat gctgaaatcg acatcgtgta cattgctgta ccaaatagac
    14581 agcatatcga ccatatcttg gcagcattgg aagcaggcaa acacgttcta tgtgaaaaag
    14641 ccatcacgat gaataaaaaa gaactggctg acgctatgcg cttagcagaa gaaaagaatt
    14701 tgatcttagc agaagcgatg acaatcttca acatgccact ttatcagcag ttacgctcaa
    14761 taatggatac aggaaaactg ggggctttaa aaatgatcca agcacctttc ggcagttaca
    14821 aagaaccaga ccctaaaaac cggttcttca atccagaatt agctggagga gctctgttgg
    14881 atatcggtac gtatgctgta tctttcgctc gtttcttttt gagctctcaa cctgaagtag
    14941 ttgcctctac aatggttcct tttgaaacag gcgtggacga acaatccgtc actatcttgc
    15001 gtaacaaaga aaatgaactt gctgctgtca gcttgacttt tcaggcaaaa atgccaaaag
    15061 tcggtatcgt tgcctttgag aacggttatg tgacgattgc tgattacccg cgtgctgatc
    15121 gtgcggagat cttatttaca gatggtacaa aggaattcat cgaaagcggg aatacatctg
    15181 aagcaatgaa ttacgaaata aagaatatgg tacacatgat tgaaggtgac ttgcccaatc
    15241 gctctctctt cttgacaaaa gatgtcatcg aaatcttgga tcaaatgcaa gttctatgga
    15301 aaaatatgta attttaaaag gttgtgaaaa agctgttctg catcaagtaa taagaacagc
    15361 caaacaaaaa tagctcctcc tatttttcgt ttggctggac ttattaccgc agaggaaagc
    15421 ttttgaacac cgtttaagaa agaggttgtg agcctaccgt tcagctccga gtcacaagga
    15481 gcaatttcaa aaaacagctt ctcatgtttg ttgaatattg tgacttgtga ccgaggagtt
    15541 gacaggagaa caccgtttaa agaagaggtt gtgaaatcag ctttttgacc tgaatattag
    15601 ctgaattcac aacctctatt tttggatttt ttgttgggag aattctgcct tgatttcaat
    15661 aaaactttta aaagactgca aaaactggaa caattctgct cgatcctcga attcagggcg
    15721 actagtcggc agaggcattt gccgatacaa tacataaact tcttcaatac gtgttaaaat
    15781 ttgtctgcca tcatttgact ctgaaaatgt ttctgcagta taaatcaata aaccatagat
    15841 atgttttcca taataagctg gttgctggat tctctctaga ttttccagca tgtctttaat
    15901 cacattggcc tgtgctcttc tcatagagaa gtaagtttcg tagtatagcg gctgtctgag
    15961 ccagtagttt tcttgatgtt ctctggcatc ttcttggctt tcgcgaatga atgtcagtaa
    16021 atgttcgcat ttgatctgca catcttcttt attttctgat aaaagaaatt ctgccatttg
    16081 tctcaaaata tttcgaaatt ctttttcgat ctgtatttgg ttttccttca gctgcttcgt
    16141 acgatctggc atgtaaacat ttgcaagcaa agcaaatact aatccaatcg ccattaatcc
    16201 cgcttcattg ccgatcagct gccaagacat gttttcctcc actaaataat gagtgaccaa
    16261 aaccgaattt actactatcc cttcggttaa tttgaagcga gaggcaagcg ggatgaacag
    16321 gaataaaaaa agactgaagc caaaaatagt atacccaaca gcaaaaaaac tgaacagtgc
    16381 tgttgccgta gctaatataa aggctgcgat tcgattcatg cccgtacgca atgtagagcg
    16441 cttggtattt cctacactta ataatgcaat gatccctgca gctggccaat acaacagcga
    16501 taagctaccc gctgtgacca tcgaaaagaa gacactgatc actgttttga ctgttcgcat
    16561 tcctatacgc atttacttcc ccctttttta ttttaattat acttgaataa tgaaaaacta
    16621 gctatcagac aaaagtttag gtatgatagt aaaaagacca aaaaggagaa tctctatgca
    16681 atttggccgt tttcgactag gtatgcgtac gatcaaaagt gccttagctg tttttttatg
    16741 tatcttgttt tttcatttga ctcaacgagg aatcccgatg attgctgcat tatctgctgt
    16801 tttttctttg cgtcaggact tgactacaac cgtttctttt ggaaagtcta ggatcatcgg
    16861 caatacatta ggtggtacat tagctatcat ttattttttt gtcaaaagct attttcacaa
    16921 tgattttttg gtagaattga tcttgcttcc tattctagtt attattgtga tcgtcgtgtc
    16981 agatggtatt aacaataatt ccggtatcat ttccgcaata gctacgttgt tgctgattgc
    17041 gttgagcatc cctcaaggcg aatccgcttt gtatgctatc caacgtgtac tagatacttt
    17101 tatagggaca ttcattgcaa tcggtatcaa tttctttctt cgtcctcctg aaacagaaaa
    17161 gaaggaagaa ctatcagaag atttggtcga actccaaaag aaagaacgat tgctaagaac
    17221 aaatttacaa gagatagaag ctaagatcca aaaacaaaag aaaaatagcg aggactaatt
    17281 ttcttttgca ataaaataaa aaaatggaga gaagaacttt aaaaagtctt cctccatttt
    17341 tgattgaacg gtgaagtgta ctactttatt cttccttcat cgagttttgt tctgcctctt
    17401 ttggcgcttc atacatattt acttggctag tagtcccacg tgtcgacaaa ttctctacga
    17461 tttccttcaa gtcaagtcct gttgtcgctt ttagtgtttc ttgagtagaa gaaagcaaat
    17521 ttgtggcata atttgtcact cggttcgctc cactggtttc tcctgaactg cttcctgtat
    17581 cgacaacaga gattttttcg atatttccta gcggctgtgc tgcttcgcgc atcaattgcg
    17641 gtagcatatc gataaccata ctcaagacag ctgcttcgcc atattccttg aaggcattgg
    17701 cgatcttttg ttttgcttcg gcttctgctt ttccttttgc tagtgctgct tcggcttctg
    17761 cttgtccagc taaacgtgtc ttattggctt ccgcttctgc cagtgcttcc acacggaatc
    17821 gttctgcttc ggcttcagtc acttctttga ctttttgagc ttgtgcttct tgttctttag
    17881 cgtaccgatc ggcatctgct tttttcttca cttccgaatc atattgcttt tcacgacgtg
    17941 tgatttcttt ttcttccagt tcgatttgtt tttggcgttc tacgatttta atctgcattt
    18001 cctgttcgat tacttgttgt tgtgctcggg cactttctaa attgtaggct tggtctgctt
    18061 ttgctttagc aacatcttgt tcttgtttgt aggttgctaa tttcagttct ttttctttta
    18121 atgattctgc gatctctgtt tgtcgctgta attcagctgc ttgtgattct ttttctgctt
    18181 gagctttttt gatacgcgtt tcttttagag cttccgcttc tgctatatct gcatctcttt
    18241 tgacttgggc gattcttggt ttccctaaag agtcaagata accgtttttg tctctgacct
    18301 ctttgatagt gaaagaaacg atgatcaacc ccatttttgc aaggtctaca gaagcgactt
    18361 cttgtacgct ttgactgaac ttatcgcgat tttgatagat ttcttctaca gtcatagaac
    18421 caagaatcga gcgcaagtgt ccttctaata cttctcttgc ttcattttcc agttcttctc
    18481 ttgtcttgcc taaaaactgt tctgctgctg tagcaatctc ttctacagat gaaccgattt
    18541 tgatgatcga agtaccatca cacatcaccg gtacgccttg ttccgtatac acttcagggg
    18601 tggagacgtc caatttactc gataatagac tgatccgatt cgaacgttga aaaactggca
    18661 agacgaatgc gccacctcca cgcacaattt tgattttgtt attgctttca tcaatgtgca
    18721 catttttgct tcctaaataa cttccactga tgatcaacgc ttcatccggt tttgctgtct
    18781 ggtacttcgc tacaaagacg atcagcaaca tcagtaaaat caaagctgcg attgcgatcg
    18841 cgataaaaac aactggtatt tccatttaac acacgctcct ttaagctttt atcatgcttt
    18901 cataaggcat gacataacag attctttcct tgatctcaat gatcaatact ttcgttcccc
    18961 gctcagctgt ctgttcttgg gggctgtaaa aacaagctgg acgactaatg gaaccggtaa
    19021 cacttttcaa ctgaatttct cccatacctc gtacagggat cggtgtgatc acaacagcta
    19081 cttgtccttc cagagttttt tcagaagacg acatcgttga ttcggcatgt ttcatcggca
    19141 tcaatatata gaaattaagc aaaaatacca acactatcga tatgcctcca ctagcaataa
    19201 ataaaaataa agatgattga tctgttaaac gctcacctag aaaaccaaat aagcttgtga
    19261 aagttaacca agggataata agcatcggat caagcgggcc atcaaaatcg aatacatctc
    19321 caaaaataat caataggact gccaatcctg cacaaatcag caatgtatac caataaatcg
    19381 tctcaagtgc gattccccct atcatataca cgcctccttc catttctacg tctatcatac
    19441 caatgtttga aaattctgta tagcttcttt taccgactca gtggtgtttt ttataggaag
    19501 gttgtgttta tcgttgacaa tttgttaaat ttttgttttc atgttaaaat tttcacaata
    19561 aattctttcg aggtagccta tgtttccttt ttttaagaaa aaaccattaa agctccagaa
    19621 cacgatcatc cttgtcgttt gtttctccac attcgtttct ttgattgttt ctgccatatt
    19681 gatcaggaat tttattcttt cgatgaaccg atctagtgtg tcagataaaa tctctagcat
    19741 tgctaaaatc gttgccaatg ataaactcat ccaaaaaaag ctgcagactg gtgacccgac
    19801 acatgcgatt caaggaataa caaatgaaat catgattgca tcgaatttag attttatcgt
    19861 tgtcatggac cctgaaggca ttcgatattc tcacgcagac ccaagttaca tcggtcttcc
    19921 tttctcaagt catgaagatg tgaaaaaagt gattggagga caagaatttt tctctgaaaa
    19981 agaaggaatg ttagggttcg gcttccgcta tttcgtccct atttattatg atcaagagat
    20041 tattggtgca gtttgtgttg gcttaacaaa caacacgatt gacaatcaag tcaaagatgg
    20101 acaaaaaatg attgtttttt cattgattat tggacttagc gtaggcatca taggcgccgt
    20161 ttttcttgcc caaaaaatga aaaaagtact gcttggactt gaaccacaag aaatagcaga
    20221 acagttaagt gaaaaaacga ttatcgaaaa tgaagtagat gaaggaatct tagccatctc
    20281 ttctgataaa actatcctct tgatcaatac acctgcaaaa aacattttct accaaacaga
    20341 gcagctattg gatttcgaag taggaaaaaa atcagtgata atctatatga cgttttgttt
    20401 aaagagacga ttgagcatca aacgaccgtt cggactcaat ccatgtattt aaatgggata
    20461 gaaactattt ctagcgttac acctcttttt agcaatgacc gttttttagg agcagtcgca
    20521 actttacgaa atcgatcaga agtaatgaaa ttaatggagg agcttggggg gacgaaacaa
    20581 tatataaact ccatgagagc tcaaacccat gaattcatga ataaacttca tgtcatttct
    20641 ggtttgattg atttgaagaa gtatgaagaa gtcacccatt ttatccagca gctaaatcaa
    20701 aattataaaa aagagattgg ccaagtctca agtctgatca aagtacctgc aattgccggt
    20761 tttttattag gcaaaataaa cgaagccaaa gaacaatctg ttgaaatgct gttagaaagc
    20821 gattctttta tccctaaaat ggagatggat gactccatcc attcactttt gcaagtgtta
    20881 gggaacttac ttgataatgc aaaagaagcc gtgctacaaa aacatgaaag aaacggacag
    20941 gtccggattc atttaaacta tgacacagaa gctgaagtat tcatcgtgac cgtctgcgat
    21001 gacggtgtcg ggatatcaga agaaatctca gaaaaaatat ttacgctagg tttttcgacg
    21061 aagggaatca atcgtgggtt tggattgaat ctcatccatt caatcgtcaa acgccacggt
    21121 ggatttttag aattttccaa acaaacaaat ggcggtacaa tcgtctatct agaattacca
    21181 aaaaaggaag atcaaaatga tgacaaatgt cctgataatc gaagatgatc caatggttgc
    21241 agaattgaat cgtacttttg tggaaagcat ccctaatatg aacgtaatcg aaagtttcag
    21301 aaatgtagaa gaaggaaaaa aatatttcag acaaaaaaac gcagatctgc tgctgcttga
    21361 tgtatacatg cctggcgaaa gtggtatcca ttttttatct tggcttagac agcaaggaaa
    21421 tgatatccca gtgattttga tcactgctgc agatgatatc gaaaccataa agaatgtgat
    21481 ccgctacggt gccttagatt atttgatcaa accgttcact ttgcaacgtt ttcagctggc
    21541 gatcgaaaag tatcttgctt tctctcagac aatccaaacg actgaaaaag ccgatcagaa
    21601 attgatcgat caagtattca accacaccac tcccattcac gaaataccat cattcatcga
    21661 tttgcctaaa ggtctgtcaa aactgacttt aaaaaaaata agtgcattta ttctaaaaga
    21721 agatactatt ttttcaacaa aagaactggc tcaaaaaagc tcactgtcac gtatatccgt
    21781 caagaaatat ttgaattttt tagtagaaca agatatattg aacgaaagaa tcaaatattt
    21841 ggaaatcggc cggccgctaa cctgttatga attgacaaag aatgggcgga aaaagctcac
    21901 agattactgt tgagtcatcg aattatccca tacaaaatag tccaagtata cagaagtaac
    21961 aactgtttac ttggactatt tttaaacatt ttattgacga atatccatgt tttcttatct
    22021 taattgacgg gctttaggaa gagatacctc atttttcgtt tttccagttt ctattatttc
    22081 acgaaagttc tcgaaacttg tcgaaatcat atttgataat gcctcatctg tatttgaacc
    22141 tacatgcggg gttacaagaa ctctagggta catttctact aattgctgga tagcagggtc
    22201 tggaatcgtc tcccatggct tgaaggatcg gaaaaaaacc tctgtttcat ttgcaaaaac
    22261 atcggttgca aaaccagcta aatgattgct tttcaaagct cttaaaatag cttcattatc
    22321 ttgaagctct ccacgggctg tattaatcaa gatgctacct tttttcattt gagctaaaaa
    22381 tccttcattg atcatttgat cgttttcacc tgggatatga ggtacatgaa tactgacaat
    22441 atcgcttttg gctaataact cttcaagcga gtggaacgtc aatacttttt tagcagcttc
    22501 tgtctgatga atatcgtagc cgatcacttt ggctcctagt cccttaaaca aaacagcttc
    22561 cgtcaaccct atcctgcctg ttcctatgat ccctactgtg caatttctga tttcacgact
    22621 aaacatttgc tcatccactc gaaaatcttt gaaagatgtt cggatcgtcg tatacgcagt
    22681 atttctcaaa agcatcatgg caaaagtcaa agataactct gctatcgcat ttggcgaata
    22741 cgatggtaca cgggctactg tcataccaaa atcagctgcc gcttgtagat cgatatgatt
    22801 gactcccaca gtccgtgtaa aaacataacg aatcccatat tcctgcattt ttgcaagatt
    22861 ggtctcatct gctatacaat ttcccctcaa caatacagca tcatggtcct ttgctgacac
    22921 gatattgtca tgtgtcaaca gttcttcata aagactgaga tcataatggt aaatattcaa
    22981 tttttcaaaa aaatctatct cgttcggacg aacaccgtaa catgcgattc tcatactttc
    23041 ttcctccatt tcttatgaaa ataaacctat gccatgaatc atttgtaata caacgatcca
    23101 tacaggtgtc agtaccacag caaaaatagt tgacagtaag gatgcattgg aggctaaaag
    23161 tgcctcccta tcaaaactga tagcataggc tgctgccact gttgcagctg gtgtagccat
    23221 catgataacg attgttgcca gtgcttcaaa attgactggt agaatattcg ttgccgtcaa
    23281 aactgctaga atcacgatat tcaatgcagg tacaaatacc actttgacta gactgtaata
    23341 ccatgaagtt ttttcagatg cagctttttt gaagcttact tcacctaatg ttgcgccgat
    23401 tgctagccac gccaatggtg aacttaaacc agctaaataa tccatcggct gaaatagcca
    23461 cggtgcagtc tggtcaattc gcaaaaacgc tacttggctt atctctcctt ctgcacctgt
    23521 aactgacact tgtggcagat acccttggaa cagccaaatg aaaaggccgg caaaagtagc
    23581 gataatgatt ggattgacga acatcgcttt gatattttta gcttccatct tcaagccact
    23641 catttttatg tatccataag aatacaaaaa gattcggtag ccaatattga aaattgagga
    23701 atacatcacg ccgacaggac cataaatcgc actgacgata ggcgttccga aaaaggtcgt
    23761 agaaccaaag atcgtcagga cacgcaacgt tgtttgctta tcccctttat agcttaagaa
    23821 aaaaggtttt gaaactagaa taagaataat ataaataact aatccccaaa tcaagacatt
    23881 gattccttgc atcagtaatt ctgtattgat atcttgcatg aaagctcgaa atgccagtgc
    23941 tggcaaagcc actgttaaga cgactttcga tagaattttt ccaacagatt cagaaaaaat
    24001 cccctttttt ctacaaacaa accctaataa tataataaaa actgttgaag tgattgcact
    24061 gacaatcgac atatctgtca aagtcgatcg aaaaatgtca aataagttca tctttctcct
    24121 cctaattatg ttcatttatt cacaataaaa aaaagctttt attttgctaa tacgtattaa
    24181 catttttaat tttatcttta cattgttact tattgaacaa taggaaatta aagaaacttt
    24241 tgaaacttat gtaaagtgat ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa
    24301 gaagtttagt tttaaggtta acttaaatta tattatgcgt ggaaacgttc cacgccatct
    24361 agataagttg cttccaatgt catatcaggg ttcaatacga taaagtctgc atcgcgtcct
    24421 tgagcgattt ttccacatgt atcatcgatt ttacagctga ttgctggaat cagactagcc
    24481 atcatgactg cttgttctgg tgttgctaat ccccagtcta caacattttt aattgcttct
    24541 ttcaatttca atatacttcc agctaagttg ccagattcta gacgtgctgt tccttctttt
    24601 actactactg gaaattcgcc taaattgtaa tttccatcag gcatcccacc ggccatcata
    24661 cagtctgtaa ttaatgcgac atgatcatgt cctgcttttt ccattaggat tcccgcagca
    24721 tttggatgta catgatggcc atcacaaatc aattcagaaa agacatgttc taaagataat
    24781 aacgcaccca ccatacctgg ttcgcgatga ttcaatccac gcataccatt gaaagcatgg
    24841 acaaatacac ttgcgcctgc ttcaacagct ttttgcgctt cttctagtgt agcattactg
    24901 tgtcctagag aaacaactac tccttcttca gtcacttgtt tgacaaactc ttctacacct
    24961 tgacgttccg gtgctaaagc aatttttttg attaaaccac ctgaagcttc ttgccattca
    25021 tggaaagtat ccaaatcagg atccccgaaa taacttgggt tttgtgcccc tttgtgttct
    25081 tctgtgaaga aaggaccttc aaaatagatt cctttgattt tagctcctgg tgcttcctga
    25141 tacattttgc cgattgtctc agctacatct tttaaacgtt ctttgcttga cgtcaatgtt
    25201 gttggtaaaa atgaagtcac tccacaagat aacagacctt cagacatcac tttgatgcct
    25261 tctgcatcat tatccattac atcatgattc atatagccgt gaatatgtgt atctaccaaa
    25321 ccaggagcaa tccatttgcc gctttggtca atgatgttga cttctccctc aggtagttct
    25381 ttggtgtatt caccaaaaag tccatcggta atttcaagat agcctgcatg tttgacacct
    25441 gacgctaaaa agaatttgtc agcatagata aaagttctca ttctattctc tccctttgtt
    25501 tttctacctc taaagtactc ttatttagag aagaagtcaa gaatggtcta caccatttac
    25561 aaattttttg aaatttgttt cacagcttgt gctaagcctt catagaatgc tgctctttct
    25621 ggttcttctt tacgcttgta tattaagctt ttaagcacaa ataaatcatt gaggtaatag
    25681 tagctattct tctcttgagc ccaatagatt ccttgattca cctgttctaa cgcttcgtcg
    25741 atttcatttt gatggaataa gaaatttcca taattataaa aaatttgcga aaattcactt
    25801 tttgatcgtt catcagctga ttgatgcagc agttggatgc ttcgactcaa atagtagcgt
    25861 gcttcagccg tttttcctgc cacaccatat atttttccga tacaactaat cagttgtatt
    25921 tctgtgtcag aaacatggat tctttctttt tggctagagt agcttaatgc ttctttcaaa
    25981 taataaaggg actgagagat attttgacgc aacgtgaatt cgcaaacacc gagataataa
    26041 taatagcgtt gaaagtcagt tgcttgatac agattttcag aaatatcaga agattttagt
    26101 acttgttcta acttccgata atcacgtttt tggaaacaac tatccaacag ttcaaataat
    26161 ttatcgtttg tccgagtagt ttttcgagag agattcatca catgatcaat cgttacccct
    26221 agccgttgac aaatctgcat catcaccaat acattcggca gttcctcatt attttcgatc
    26281 cgacttaata cactttgtga acaaatatca tgcgaaagca ttttttgcgt cattttttgt
    26341 tcttttcgaa tctctttaat gatcgttcca aaggactcga ttaacgtttc cataagtatc
    26401 ctccccaaaa tatgcgtatt cgcattctat tcgtatttta ctttaggaag tcgcaaactt
    26461 caagaaaaga cttgcaacta aataatatac tttagttatt taagaaaact ccactagaaa
    26521 gagagcctca gtgtgtttgt ctgtggccct cctactgaaa aatttggttt ttaaaatcat
    26581 ttttggcgat aggttgctag gaattctctc attttcttag ctgtttgttt caaatcatcc
    26641 attttaggaa gataaacgat tcgaaaatga tctggctggt tccaattaaa tccaccacca
    26701 tgtacaagta gaatatgatg ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa
    26761 atattgaatc gctttgtatc aatttttggg aatatataaa aagcagcttt tggttttacg
    26821 gctgaaagac caggaatatc attgattgca ttatagatat attctctttg ttcatagatc
    26881 cttccgcctg gcaggagcag ctcatcgaca ctttgataac cgcctagcgc ggtttggata
    26941 atttgctgag acaatacatt ggaacacaaa cgcatggagg acaacatatt cagcccttct
    27001 atatagcctt tgacgtgtga cttatctcca cttaggacca tccagcctac tcgaaatcct
    27061 gctacacgat gagatttgga tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat
    27121 gtagcaatcg gaatatgttc tagaccatcc atcactaagc gatcatagat ttcgtcggaa
    27181 taaataatca ggttattttg tcgagctact tcaacgattt cttctaataa ttcttttgga
    27241 taaagtgccc cagtaggatt attaggatta atgataacaa tagcttttgt ccgactcgtt
    27301 atttttgatt tgatatcatc aatatcagga taccattctg cctcttcatc gcaaatataa
    27361 tgaacaggtg tgcctccagc taatgcaata gaagccgtcc acaacggata gtccggcatt
    27421 ggaaccagta cttcatctcc attgtccagc aacccctgca tacacatcgt gatcaattcg
    27481 ctcactccgt tgccggtgta gatatcattg atcgtcacat tcggaaaatg tttcagttgg
    27541 caatattgct caattgcttt tctagcagaa aagatcccct tggaatctga gtagccttct
    27601 gagtcacggg cattcatgat caaatcacga atgacttcgt ttggtgcttc aaatccaaaa
    27661 ggtgcgggat ttcccgtgtt caattttaaa atactaatgc cctcttcttg catccgctcc
    27721 gcttcttcta gaacgggacc gcgaacatcg taactgacac cttctaattt gttggatttt
    27781 tcaaattctc tcatcactta gccaatccct catttcaaaa agttagaact ttccaaattt
    27841 tttgttattt actatttcaa tatcatactc catcctagaa aattttgcca cttatttagg
    27901 aaaaacgtaa gtattaaaaa aacacaaaca agcgttgaga acttaattgt catgatagtc
    27961 attccataga ttcgctgccc aatccattgc aattccacaa atgattccta gcataaaacc
    28021 aagcaaaaaa cgtccgaatg caagtccaat caatacacct aagatcattc ccagtcctga
    28081 aaattctccg tcatatttct ccatcttaat aagtcctccc atttttgagc ttgacaacta
    28141 tgtaaaacct cgctatcatt agtgtgttat tattacgcag atgtgttgga attggcagac
    28201 aagcatgatt gagggtcatg tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca
    28261 ctacaactcg tgaagttaat tttgcttcac gagttttttt gtttgaacgt ttctttatgc
    28321 cattatatac atatcactgt atcctttaca aaaagaacgt acaatcatgt aaacagcctg
    28381 aggtgagtat atgaaggtcg gaaacaagct actcgtagaa acttgcaagt gttaaaacaa
    28441 ttaatcgaaa aacgagtaaa atccctcacc taatactaaa gcgagggatt ttttgtatat
    28501 tatctgttta tcaccgttat tataaaggta caaataccaa gcacggttaa tccaaattgc
    28561 ataaattcat ttttttgtac actcatgctt ttcattagct ctttaactgc cattagtact
    28621 aagatggcga taacaacata aagtatatag tacgtccgca ttccggaagc ccatactgtg
    28681 ggagaaaatc ccataattaa ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa
    28741 atagaagttt tcttattgtc aaaacttaaa taaattccaa caattaaaca tagtaataat
    28801 gccaagacta ctaaagtagc tatccaagta cctggataaa aaagtgacag tttcgttcct
    28861 aactctgtaa agagattatt caggttacta ctactccaaa tcattgccct tttatttcca
    28921 ttgacgtaag taaagctttg acccattgta ttaccaaaat aaataatcag gtttaagaaa
    28981 aacggtaatg cagtcaatat acgcacataa tagttttgac atttcctata tgttagaagg
    29041 aaaattaaga aaaatagcaa taaaaataag atattcatgt ctaaaaaaaa cggctttcca
    29101 aatgatgaaa tacctaaatc taacttatta agaaagttga aa
//
LOCUS       DADVXM010000026        29110 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.027, whole genome shotgun sequence.
ACCESSION   DADVXM010000026 DADVXM010000000
VERSION     DADVXM010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.027"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..1030)
                     /locus_tag="KB927_001261"
     CDS             complement(<1..1030)
                     /locus_tag="KB927_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6840189.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="KB927_001262"
     CDS             complement(1112..1801)
                     /locus_tag="KB927_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6840190.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="KB927_001263"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="KB927_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBB6840191.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="KB927_001264"
     CDS             complement(2328..2831)
                     /locus_tag="KB927_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBB6840192.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="KB927_001265"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="KB927_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBB6840193.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="KB927_001266"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="KB927_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBB6840194.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="KB927_001267"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="KB927_001267"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBB6840195.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="KB927_001268"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="KB927_001268"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBB6840196.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="KB927_001269"
     CDS             complement(6443..7462)
                     /locus_tag="KB927_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBB6840197.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="KB927_001270"
     CDS             complement(7635..8540)
                     /locus_tag="KB927_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6840198.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="KB927_001271"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="KB927_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBB6840199.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="KB927_001272"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="KB927_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBB6840200.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="KB927_001273"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="KB927_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6840201.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="KB927_001274"
     CDS             9753..10397
                     /locus_tag="KB927_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6840202.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="KB927_001275"
     CDS             complement(10453..10956)
                     /locus_tag="KB927_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBB6840203.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="KB927_001276"
     CDS             11553..12518
                     /locus_tag="KB927_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBB6840204.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="KB927_001277"
     CDS             complement(12617..13789)
                     /locus_tag="KB927_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6840205.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="KB927_001278"
     CDS             complement(13776..14921)
                     /locus_tag="KB927_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6840206.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="KB927_001279"
     CDS             complement(14935..15867)
                     /locus_tag="KB927_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840207.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="KB927_001280"
     CDS             15984..17063
                     /locus_tag="KB927_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6840208.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="KB927_001281"
     CDS             17060..17689
                     /locus_tag="KB927_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6840209.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="KB927_001282"
     CDS             complement(17799..18026)
                     /locus_tag="KB927_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6840210.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="KB927_001283"
     CDS             complement(18129..20717)
                     /locus_tag="KB927_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBB6840211.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="KB927_001284"
     CDS             complement(20737..21396)
                     /locus_tag="KB927_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6840212.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="KB927_001285"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="KB927_001285"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBB6840213.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="KB927_001286"
     CDS             complement(22169..23035)
                     /locus_tag="KB927_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6840214.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="KB927_001287"
     CDS             23144..23785
                     /locus_tag="KB927_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBB6840215.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="KB927_001288"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="KB927_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBB6840216.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="KB927_001289"
     CDS             complement(25226..26125)
                     /locus_tag="KB927_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6840217.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="KB927_001290"
     CDS             complement(26127..26924)
                     /locus_tag="KB927_001290"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBB6840218.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="KB927_001291"
     CDS             complement(26902..27606)
                     /locus_tag="KB927_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBB6840219.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="KB927_001292"
     CDS             27737..28312
                     /locus_tag="KB927_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBB6840220.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="KB927_001293"
     CDS             28430..29107
                     /locus_tag="KB927_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBB6840221.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8566 a         6169 c         5232 g         9143 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaaaaa
//
LOCUS       DADVXM010000027        27865 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.028, whole genome shotgun sequence.
ACCESSION   DADVXM010000027 DADVXM010000000
VERSION     DADVXM010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.028"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(424..1368)
                     /locus_tag="KB927_001294"
     CDS             complement(424..1368)
                     /locus_tag="KB927_001294"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBB6840222.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1664..2608)
                     /locus_tag="KB927_001295"
     CDS             complement(1664..2608)
                     /locus_tag="KB927_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6840223.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2829..4043
                     /locus_tag="KB927_001296"
     CDS             2829..4043
                     /locus_tag="KB927_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6840224.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASIYGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4065..6080
                     /locus_tag="KB927_001297"
     CDS             4065..6080
                     /locus_tag="KB927_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase"
                     /protein_id="HBB6840225.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEETFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6163..7536)
                     /locus_tag="KB927_001298"
     CDS             complement(6163..7536)
                     /locus_tag="KB927_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBB6840226.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7562..7846)
                     /locus_tag="KB927_001299"
     CDS             complement(7562..7846)
                     /locus_tag="KB927_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6840227.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7848..9863)
                     /locus_tag="KB927_001300"
     CDS             complement(7848..9863)
                     /locus_tag="KB927_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6840228.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIKKGDE"
     gene            complement(10042..10347)
                     /locus_tag="KB927_001301"
     CDS             complement(10042..10347)
                     /locus_tag="KB927_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBB6840229.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10436..11467)
                     /locus_tag="KB927_001302"
     CDS             complement(10436..11467)
                     /locus_tag="KB927_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6840230.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11674..12549
                     /locus_tag="KB927_001303"
     CDS             11674..12549
                     /locus_tag="KB927_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6840231.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12701..13543)
                     /locus_tag="KB927_001304"
     CDS             complement(12701..13543)
                     /locus_tag="KB927_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6840232.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13635..15512)
                     /locus_tag="KB927_001305"
     CDS             complement(13635..15512)
                     /locus_tag="KB927_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6840233.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     RPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEATIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIDNQTNTPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDHETSGTYAYVLYDG
                     DKEIDPTNYSVTEQTNGFTVSVDSNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15509..16930)
                     /locus_tag="KB927_001306"
     CDS             complement(15509..16930)
                     /locus_tag="KB927_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6840234.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16933..20322)
                     /locus_tag="KB927_001307"
     CDS             complement(16933..20322)
                     /locus_tag="KB927_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBB6840235.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20579..21970
                     /locus_tag="KB927_001308"
     CDS             20579..21970
                     /locus_tag="KB927_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6840236.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(22043..22690)
                     /locus_tag="KB927_001309"
     CDS             complement(22043..22690)
                     /locus_tag="KB927_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBB6840237.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22698..23384)
                     /locus_tag="KB927_001310"
     CDS             complement(22698..23384)
                     /locus_tag="KB927_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840238.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23390..24463)
                     /locus_tag="KB927_001311"
     CDS             complement(23390..24463)
                     /locus_tag="KB927_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6840239.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24685..25359
                     /locus_tag="KB927_001312"
     CDS             24685..25359
                     /locus_tag="KB927_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6840240.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25364..26704
                     /locus_tag="KB927_001313"
     CDS             25364..26704
                     /locus_tag="KB927_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6840241.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26853..27839)
                     /locus_tag="KB927_001314"
     CDS             complement(26853..27839)
                     /locus_tag="KB927_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBB6840242.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8128 a         5274 c         5044 g         9419 t
ORIGIN      
        1 aaaaatgata aacctctctc gaacggtttt ttatcaaaaa tcgtcatttt tccatcaaaa
       61 tctgcttatg caaaattata aaaaaatttt gcagtttttc ttactttttt tgtcgtttaa
      121 ttgaatgata aaaaccagtt tctttattca gttaatcaaa tatgaacgaa ttagatatga
      181 atcattgtat ttgccgttgc ggaaggattt tttaattaac cacagataaa cattgataac
      241 gattcgctta ttgtaatcaa cagattaaat ttcatatgtt catatgtacg gatacatttt
      301 cggaccgatt aattttaacc attctgttta tttgcttacc tattagatat caataaaaaa
      361 ctgcttaaca gctatttcag ctgttaagca gttttaggat ttttagttca tattcattgt
      421 ttcttataat acagtgttca atacttctct taaagcactt gttgatttgc tgaacattgc
      481 tttttcttct tcgttgattg ataattcaac aacttcacga acaccatttt cgtcaacgat
      541 tgatggcaca cctgtaaaga tatctttttc gtcgtattca ccagttaaat aagcagatac
      601 aggcaataca gcttgttcgt tattcaagat agcttttacg atacgtgcag tactcatacc
      661 aataccatag taagttgctt ttttacgatc aatgatctca taagcagcat tacggacttt
      721 atcagcaatc acatctaatt catcttgggc aatacgatgg tctttttcta caatttcaaa
      781 cactggttta ccaccgacag ttgtatgtga ccatgcagca acttctgaat caccatgttc
      841 acctaagata tagccgtgga cgctgcgtgg gtcaactttt aatttcaatg cgatttcttt
      901 acggaaacga gttgtatcca atgttgttcc agtaccgata acacgtgatg ttggcagacc
      961 agattcgttc caagcgatat atgtcaaaat atctactggg tttgaagcaa caacgataat
     1021 accgtcgaat cctgatccca tgatttcttt tacgatttgg cgcatgattg acgcatttgt
     1081 tttaactaaa tctaaacgag attgaccagg tttttggttg ataccagctg tgataacaac
     1141 gatatcagca tctttacatt cttcatagcc acctgaccat acagccacat tttcatcgcc
     1201 ccaagccata ccatctaaaa ggtccaatgc ttccccttct gctttttctt gattcacatc
     1261 gatcaatact aattcattag agattccttg gttgatcatt gcataagcga tacttgttcc
     1321 aacaaaacct gtaccgacga ttactacttt acgacttgtt tttttcatga ataaacagct
     1381 ccttttcata actatttgtt actttcatga aaagtatagt cttgtttatt cattttatca
     1441 acatgttaat tataatagtt gttattataa tttttgatgg aaacgaattc ctgaatacgc
     1501 ataacagata aatgacaaat gtttacacct atatcccctg ataatacaac caaaagttta
     1561 gaactgaaaa taaatccaaa aaaattcgct gcaacgatat aataagacag caatcgcacc
     1621 taaaacaatt ttccttcata tgctttagtg aaagattttc ttcttaatgt ttatttctcc
     1681 attcattggg agtacatgtt gaatacttct tgaataattt gaataaagaa gtcgtttgtt
     1741 tatatccgat acgattagcg atttcttcca acgaaaaact cgtttcttga atcagttcca
     1801 acgcaaagtc gaattttttc tttagaacca gttcttgaaa ggaagcatca aaatacattt
     1861 tcaatttatt actaagatag accggattgt agccaaaatg agctgctgtt tcttttaacg
     1921 tacaagaagt aaaatgctta tcgatataat ctaatactct aagcatctca ttttctgcgc
     1981 atccatctgc tgatgaaaag ctttgttgtt ctaataaatg agtcaattcg atcagtaata
     2041 gtgatgtata gagatttaac gaacggatct tatgactgta tgtatcaaaa taaatcaaca
     2101 gcatattttc aatcaaatgc gtcaaacgac ttgtttttcc gccgcgaaaa tgaatgaatt
     2161 gtgtatgttc ccctttttct tttgatgcat ttatcaaaaa agaagaaagt agattatttg
     2221 tgcttgccaa atgattcaat atctctgtag ataaggtttc ttcttttaat aagatgttga
     2281 ttaaaatatc ctcttgccct gtgtattcga ttctttgagt agcttcttta tcaatgatca
     2341 ccacgtcact ttcttccatc tctatccttt ctccattaat aatttgtaaa catgtaccgc
     2401 tatacatata attgatttca acaaaatcat gtgtatgctc gggaacttcc gcatatcgac
     2461 ggtgtttact gatatgaata tttccctgtt gaaatagatc ccctcggtgg atttttggcg
     2521 gtgtctgaag atggtaagct aagtttaaat cattgatatt cattccttgt tcacgctgca
     2581 gagtttcgat tgattcttcg ttacgcaaaa aaaatgtcta attcagctag ttccaattga
     2641 ctccctcctt tttgtaagcg gtttctttcg cttattagtt cacgctgtac tgctattata
     2701 tgcaaagcta tttttggttt cataaagact ttctatggtt gggacatgaa cttcctgtga
     2761 ttccgctatt gagagaataa ccacttcata ctatattttt gataagcgct tacaaaaatg
     2821 aaaggaacat gcttatgaat aaaaagatga tgaaattttc tctgctgtca gtctctctta
     2881 ttttgacttc tgctggtgca gtcacgtctg caattcccag tatgtcagct acttatgcca
     2941 cgcgttcttt atctgctgtt gaattattaa cgactgctcc ctcttttatg gtcactattt
     3001 ttgttttgat tagtagtttt attgctagga aaatcggaca aaaacaaact gtgatcatcg
     3061 gattagtgat tgcatcgatt tatggtatcc tccccctctt ctcacaaagt tacagtattg
     3121 tcttagcttc aagagctgga ctaggtattg gctttggatt gatcaattct ttggcagtca
     3181 gcatgattgc tgccttttat cacggagatg aacgagcctc tatgattggt tttcaaagtg
     3241 catttcaagg atttggtgca gctttaatga catttgttgc aggacagcta gtacagttcg
     3301 gttggcaata taccttttta gtctacgcca tcagcttacc tattcttgtc ttgtttgttt
     3361 tgtttgttcc tacacctgaa acaactgaac ttcaatcaca tggcacagcc ccaacaagac
     3421 aagtaatcaa aacgaatcct aaaatgatta gttatggtat ttttctcttg ctggtcatcg
     3481 tggtatataa tgctgtatcg attaaattag ccacagtcct gacgacttat tctctaggaa
     3541 acgaaactaa tgcagcgaat atcttaacaa tcatgcaatt ggcaagtatg gctgccggag
     3601 tttgttttgg ctggcttcag acaaaagcac atcgctatat gcttacactt tctttactac
     3661 tgatgggaat cggctttgta ttgattgcca ctgtgataaa cctgtatgtg attgggtttg
     3721 gtgcgatcct aacaggaatt tctttttcgt tattcattcc ttacttattc aaccaagtaa
     3781 gtatccaagc gcccaagtac gcggagagtt tcaatacttc aatcttattg gttggcgcta
     3841 atttaggtac tttcattgca ccatatggtt tgctctttct ctcttttgct tctcttggga
     3901 gtaaaacact tgctgttttc gtcaatggca gtatcttgct gttgattagc gcgcttatta
     3961 gccttctagt agtacacagg acgaatagaa agacagtgat aagagtagat gaagaaataa
     4021 aagaacaatt gacaacaaaa taaatttgat ggaggtcgtg taaaatgaca aatgaaaaac
     4081 ataaagatag atggctttgg tatcctggag actttgagat ccgccatgga ctgctacaaa
     4141 atttccaacg ggaagaacga ggttttgact ggccagcgta ctggtacatg gatgattgcc
     4201 atcggaacgt caagtttaag agatattact ttcttgatca accttccatg tttaaagtga
     4261 cgatccaagg agttgggtat gtagaaatta atggacaaaa acatccatgt ggaaaatggc
     4321 tgacttgtcc agctggtaaa gcaaaaattc gtatctttgt aggacataca tcagggctac
     4381 cagcgatgtt tatcgaggga gacgaagtaa aatcagatat tggctggaca gcaagtaatt
     4441 ttattgaaga atatccagct ggctggagtc cgctttatgt cgatatcgca aaagatccaa
     4501 atcaaatcta ttatcaaaaa gaatgcgtcc atccagtcac tgaaacggag attggcggag
     4561 gaatcttatt cgattttggg cgagcagtga atggctgtgt agaactaata tctctggatg
     4621 accatatcga atctatcact ctatgttatg gagagtccga tgtagaagct atggatatcg
     4681 attattgcta ctataagcaa ataggaatga caagaaaaat gaaagctcgt aaacgcgctt
     4741 ttcgctattt gtttatacca gaggtttcta ctggaatggt tcaacttcaa gtttttcatg
     4801 aatttttatc tctttcgaaa caagctgctt tttcaagcga ttcttcttta ctgaatcaga
     4861 tctggtcagt atcagaagaa accttcaagt tatgtagtga tttgtttttt atcgacggta
     4921 tcaaacgaga tcgctggatt tggtctggag atgcgtatca atcattcatg atcaatcaat
     4981 atcttttttt tgacgaggaa atcaataaac gaacgatatt agcattaaga ggacaaaatg
     5041 aaatcaagca gcatatgaat actatcgttg actattcgat cttgtggttg attggtatcg
     5101 aaaaccacta tatgatgacg aaagactatg aatttttacg catcgtctac cctaagatgc
     5161 aatcattaat gagatacttg atggagcaaa cgaatgaatt agggtttatt tatgggagag
     5221 caaaagattg gatatttatt gattggtctg aaatggataa agaaggaacg cttgctgcag
     5281 aacaagtctt attactgaaa gcctatcatt ccatgatcac ttgcggagat atcttagctg
     5341 aaacatatgg agagaacgaa aattatcata ctcatctcta tcaagaaaaa tatcaactat
     5401 tgaaacaaaa cctatttgac tacttttggg atgaagaact tggcgctttt atcgattgct
     5461 atgaatctgg gagaagaaat gtgacgcgtc atgcgaatat tttcgctgtt ttattcgatt
     5521 ttgctaacaa agaccaacag caatcgatct taaagaatgt cttattgaat gacactatca
     5581 cacagattac tactccatat ttcaaattct atgaacaaga tgctttatgc aaactcggac
     5641 agacgaatat cgtctaccaa acgattcttg attattgggg agggatgtta tctcatgatg
     5701 cggtaacttt ctgggaagaa tacgacccta ctcaaacagg aaatgaaaag tacagtatgt
     5761 atggagatcc ttatggaaaa agcttatgcc atgcatgggg agcaagccca atctatcttt
     5821 taggacgcta ttttatcggt ttgtatccaa caaagccagg ttatgaagaa tttatgatac
     5881 aacctaatct agattcattt gaaacactga attgtacgct acctatcaaa gatggaaaga
     5941 tttcgcttga aaaaacaaaa gataagatcg tgattacttc tgatagaaca ggcggaacag
     6001 tgaaaatgaa tggtaaaagt tatcctcttc tagcaaaaca gccacttgtc ttaacaagct
     6061 attcaaaaat aaatgcataa aacaaaaaac tgcttgcgac atatcagaag actttaaatc
     6121 ttcttctgat attgtccaag caatttttat tttgaagttt gcttaattct gttctttaga
     6181 aacaatgttt gttctttttc cggcaaaaag aaagctagat aatacgacaa gtaaaaagaa
     6241 agcgatgatt ccaactgtca aggctatttg accgtattct cctagtttcc caagtacaag
     6301 tcctggtact agataatcag tatcggcaaa tgtagaagaa gcgattttaa gatctcctaa
     6361 tactggaagg ataaataatg gcagccaact aatcaataag ctattgaaag cagaacctaa
     6421 taccgcccct cttctaccgc cagtcgagtt gccgaagaca ccagaagcag ctccgcagaa
     6481 gaaatgtcct actaccccag gaatgataac tgtagtttgc aagcctatca tagcaaacat
     6541 ggatagtgtt cctacaaaga agctaacaaa aaagccaatt aatacagcat taggtgcata
     6601 tggaaaaacg ataggaacat ctaatgctgg tttagaatcg ggtacgagtt ttttagcaat
     6661 cccttggaat gctggaacga tttctgccaa caccattcga accccttgaa ggacgataac
     6721 aaacccagct gtgaatgttc cagcttggat cagtgcaaag attacagcgt tgtctccatt
     6781 gcttagttct ctttcaacaa atccaggacc agctaacaaa gcaagtgcga catatacgat
     6841 cgacatcaag agcatgatcg atacagtaga atctcgcaaa aagctgaaac ttttaggaat
     6901 ctttatgtcc tctgtagaac ggtctttgtt tccaaaaaac tttccgatcc atccactaga
     6961 agcataaccg atatttccgg tatgccctaa cgcaacttga ttgtttccag tgatgttctt
     7021 cataaacggt tgacaaagag caggcgtaat agttaatagt gttccttcga agaccccgcc
     7081 taataagatc atccacaaat ttgcagtaaa ccccgcgctt actaaaatga ctgctgttag
     7141 acaagaaaca taaagcattg cttgacctgt aagaaaaatg aatttatatc ttgtgaatct
     7201 agcaagtaaa atattcacga tcatccctac tagcatgatc aaagcagtag gtgtaccgta
     7261 ttgttgcaaa gcaatcgcca ctactgcttc attgctagga actactcctt gagtatgcag
     7321 agctgtttgg aacatcgaag caaaaggggt tagtgaatta ctgattaaac cagcaccgcc
     7381 gatcagtact aggaatccga caaatgtttt gatagttcct tggatcactt ctgaaaattt
     7441 cttcttctga agaacgagac caagcagtgc aatcaaagaa acgaggatgg agggctgact
     7501 gacgattgac acaaacaaat tcaacaattt atccattgat agttcctccc ttgaatcatt
     7561 tttattcttt tgacaagatc ttcgttactt tttcttttac ttcttcgctg tcaatgatcg
     7621 attgcaaagg tacgagcttt tcatcaggta tagaagttag cgtatctttc aaagaatgct
     7681 caatgaagaa ataatcagcc atatcgctag atacacttcc aacatccgta tgacttactt
     7741 caaactcgtc cacatctgct ccaagatctg caagtgcttg tttgatgttc atctctacca
     7801 taaaacttgt tcctaatcca ctttgacata ctgcaaaaat tttcatatca ttcgtctcct
     7861 ttttttatga tcgctaatat ttcttctttt gttgatgcgt gtaataaatc ttgaagattt
     7921 tgtttattag aaagtagctt tgttaaattt gccaaagccc gaagatgtgc ctcattatcg
     7981 atagcagcta aacagatgaa caaactaatg ggatgggctg gattatcaag cagatccaca
     8041 ggttgttgaa gtttcagcaa agacatccct acttcgttta cgccatcttc tggacgagca
     8101 tgaggtaatg cgatgtgatc gccaatatgg ataaacgcac catactgctc cacgcgctcg
     8161 atcatagctt tgatataact ttcttctatt ttattttctg ataatagcgg ctgtgcggca
     8221 aatgtgattg cttcttgcca gttttttggt tgatccgata attggatcat ttcttctgtt
     8281 aataattcag atagcatagg acgttgatcc tccttctttt ctaaaagttt gttcatttta
     8341 cgatttaata cttgatagag cttttcttcg tctacgcctt cttttaattc gatataaggc
     8401 agtagcgccg acaacaattc ttgggcagaa ggcattgaaa atcctggtat cagccaatct
     8461 ctttgtactt gattgatcag ctgatttttt tccaagtcag tcatgattgg atgcagaaca
     8521 tagagagact ttttcttatc agtaagtgtg agaggtacag tagaaaaaat aatatcgtaa
     8581 gaagtttcgt caacctcgtg taagcggtca gctgaattag tctctgtaaa aaagatcatc
     8641 gggaataatt gctgaagttc actttttaag atcaatgaag agctaatgcc acttggacag
     8701 acgatcacgg ctcttatttt tctatttctt tcttctgcgt ccgcttttct gatctctccg
     8761 ccaaatagta tagtgaaaaa accaatctct tcttcaggga tgctcttccc tattcgtctt
     8821 tctaacggaa gtaatgcttt tcttgtcatt tcgtagatgg aagcatattg atgcttaatt
     8881 tgatcgatca tcacattagg taaataaaaa gaataggaaa tacgaaaata ggcagggacc
     8941 aagtgataaa agacattcat caataattca cgaaacgaag caaattctac ggccatcagg
     9001 aattccatgc gatggatgac ttctgaagaa cattccagca aaaaatcaag tgcaggctcc
     9061 tggacatctc cttcaacgat cgatgctaag caaagagaga aaaatataat ctccgaattt
     9121 tgatgttcgg aatagccaag gccagtcaat acttgtcgac taatgtcagt gactgcaaga
     9181 gaagccaaca gttcagcatc ttttaccagt tccatggatg tttttccaat tcgaatggtt
     9241 gtcaaactca aataataagc taattcatcc attcgatttg gtgcgaatcg aagatctgat
     9301 agtgaaatcg ttttatctag caaatctcta actttggcgt aataatcaat ggaaagggtt
     9361 gcggttaaat acgtgagccc aaatcttcca gcaagtgact gcatcaaacg agcagtgcga
     9421 ttttttgctt ctcttcttaa tattgcttct gaccctagca gcctaaaacc agttttccta
     9481 gtatacgaca gctgacaatc ttccacttct aattcatttc ttatcttttt gatatctgac
     9541 aggactgtcc ctttagaaac ctgaagaaaa tcttgaaaat gaaaaacaga aacagacgtt
     9601 gcagtcgaat aaaccatcaa ataaagaaga tctcttcgct cttgttcggt atacacagct
     9661 tcaaatcgag taatatccaa aaatttttct gcccagtcga ttgctcggaa tttctttata
     9721 cggatacggg tatcatccac atattcggca aaaggagtta attgtttgat cgcctcgctt
     9781 gtatttactt cgatgatctc tgctgctttt tctagactga tttctcttgg tgttttcagg
     9841 agataactaa ttttgtagtt cacagcgctg ttcacctcct acttatattc tagtatggta
     9901 gcgcttttaa atcgaggggt gtttggtaca acttacagtt ggattttttt tacgactgta
     9961 ccgaacgatt tctatcgaat ggatacagaa aaaaagcagg tgaccaaatg tctcctgctt
    10021 ttatgaattg atttcgtccg atcaatgatg atcatgttta ttttttgagg tcagttcttc
    10081 aaatttttct ttgacatctt caaccgcttt ttcgatatct ttttcaaagt gattgggctc
    10141 attaggcttt gtttcctctt ctacagaatt tgaaccagat aaagctgttt ctttattttc
    10201 tgtttcacca gagtttgtgc cagctaatga ttcttctttg tcttctgttt caccagaatt
    10261 agttcctgct aaagccactt cttcttctgt tttaggggcc attgaacctc ttaatcgttt
    10321 gtgtttttca ccgtcataat ttgtcatgtt ggttcctcct agtagttcta tactttttca
    10381 tcgtacaata agacagttta tgcgtcaaaa aacaaacccg attcttacaa atatgtcata
    10441 tttttccttc tgattcttga atgcttttga ttccttcttc caaaattttc atttgtaaga
    10501 ttgtttcttc atctttgatg actttttctg cgccattaac taatgtctcg taaatccctt
    10561 cgtagacacg gctgtaatca ccaacctcgg aaattacttt ttcttcatga taactccctt
    10621 gttcatctat ataggtcaat acaccataat gttcgggcaa atcgatacca aagtcttcat
    10681 gatcaggcat gtaaaacatt ttcagatgtt cttcttgtcg atcttttgtt tgtttcacga
    10741 acatcccttt ttttccgtaa acgacgaaac ttggacgttc tttgatgcgg aaataactgg
    10801 attttatcga aattttcata tttccataga aaaaatccag atcgaagtaa tcattcattc
    10861 gtcctttccc taaaagttga cgtacatcat agctgatatc atctggttcg ccgaaataag
    10921 aaagaacttg atctactgta tgacaagcat gtccatataa atagctgttc gcagtagaaa
    10981 attcatgcgt attttctggt acttccggtc tgaaataatc ataatgcatt tctacttcta
    11041 aaatatcccc taattttccg ctttcgatta ctttttggac tgtcaagaag tcagaatcga
    11101 accgtctgtt ttggtaacat tggataaata gacctttttc ttttgctaat gcaaataact
    11161 cttctgcttc ctttgacgtt tctgcaaaag gtttctctac tagtacattc ttaccatgtt
    11221 cgagtgccat ttttccatat tcataatgaa attgactagg tgtagtgatg acaactaatt
    11281 ggatctcagg atcatcccaa agatcagaca gctgatcagt atattcgatg tcttcgaatg
    11341 ttttccacac tggttcagat ggggaaaaaa tttttttgat attgattttg ttcgtaagtt
    11401 ttcttgaaaa aggcaaatga tagcgatttg tactctttcc attgccaaga taagcgattg
    11461 taagcatgag tggtgcctcc ttttattgat gttttcagta tatcctagaa aagcgcagaa
    11521 agtatttata atagctattc tggtaaaaaa gttcagaaaa acacttgtta tcattcggtt
    11581 tggtgaaatt aatgttcaaa gtaaggataa aaatcaaaaa gatagtagcg gaaccaagtg
    11641 tttatcagta agatagaatt tggaggtcag atcatgctta ttgaagaaaa actaacaaaa
    11701 caagagttgt ttaccacgac agagaaacgg attgtcgatt acatccgtag gaatatcgaa
    11761 gctgcagtct acatgacgat tgaagaatta gcaaaagcta cgtatacttc ccattcagct
    11821 atcattcgtt tatgcaaaaa aatgggattc agcggattta aagaattccg tttcgagctg
    11881 gggcgggaag ttcatcaatt gattgctcag ttcaatcaaa cgattgatcc taattttcct
    11941 ttttcaagtg aagatagcac tcagcaaatt gcaaagaaaa tggcggattt atcgatccag
    12001 tcaataaaaa aagcacaatt gcagattgaa catgaagatt tagatcaaat cggtaaagta
    12061 ttgaacaagg cacagcgaat ctttcttttt gcaaaaggtg attctcaaat cacggcaagg
    12121 aaattccaga ataaaatggt caagttgaat aagtttttga tcatggctga agaatacagt
    12181 gattcttctt ggaatgcagc caatttgact agcgaggatt gcgccatttt tattagctac
    12241 agcggtcgca tccatcatta tgaacgaata atgacctatt tgaagcatgt agaggcccct
    12301 accttgctga ttaccggaaa tcagcattca gaaatggcca aacaggctga tatgtgtctt
    12361 gttatatcgc aggaggaata tgattttgct aaagtagcga ctttctcctc tcaaattgcc
    12421 ttcgattacg tattaaatac gttattctca gtgatatatt ctcaaaattt tgaagagaat
    12481 atccgcaact tgaaaaacaa acaagaattg atgcaaaaag gccttcttaa agaatatcgg
    12541 aaaacttaag aaaagatcct catttagtaa taagaaagat agtgtttgat aggctctctt
    12601 tgatatcatc ataaaaacag gctgaagttt tctttttcaa acctcagcct gtttgtttac
    12661 ggaacgattc gaatagatat attatagaaa tgaggaatag ctaacttctg tttcttattt
    12721 tgaacgattg acgaaaaaga tatataagaa ggaggaaaat cagtatacat gcagctaaca
    12781 atccatacag gaaaaatcgt ttgttctcgg atactttctg tacttctttt tgaacttctt
    12841 ttgcatgata aggaacccgg tgccctctga caagtaagcg atgactgttg accatataag
    12901 gtgtacaagt taggagtgtc acgaaatcct gccctttttc gattctcaga tcttttgtat
    12961 cagtcggttc taccgtcttg atctgatcga cttgataagc gagtgtccgt ccattgattt
    13021 cgatatagaa agaatcacct aaagtcagtt tcggtaagtc tgtgaacaac tttgcttgag
    13081 gcagtcctcg atggctggaa ataacggcat gtgtattttc tccccccgta ggataagacg
    13141 ttccttccaa taatgaggca cctttttcta gcagcacagt attcgtttca tcaaaaattg
    13201 gcaaatggac attgatctca gggatcgtca aaataccgat cgtatgtttc tcaaaatagg
    13261 ttctatcctt tttcgcaggt tcttttttct tagtaaaggg atctgcacct ggatttccac
    13321 cttcttttgc taattgctgg tttttctttg tcatgttttc ttggatttta gccatgactt
    13381 cttcattttc tttgaccgct tgttgctgat aatgagagat gatctgctga tccagataat
    13441 tattcagcgc gtcgctaaca aatggataag ctagtatccc tattcctgag agaagcaaga
    13501 aaagcatcag cagatctaga agtttccttt tctttggttt cattcgtgtt ctccttgtga
    13561 tgactgtttg ataataaaag aaaaaggagc atttgcgtaa tccgctgctc ctttttccaa
    13621 ttcttgcaaa aagactaaat ctgactgtgc ttgcgtctag caaagtacag tccagcaatc
    13681 agtagaagga ctactcctgc accgatatac acatagattc ccttaccgcc tgttgaagga
    13741 agtgtacctt tgtgtttatt tggtattttt tcaggagaaa tcaactgtcc tgctgttaca
    13801 taagattgtt catcgatagt aaatgctaca cggtttgtta atggaacata tttttctggc
    13861 gctttcgttt cttccagata gtacgtgcca tattttagac ctgtcacatc gattaaaccg
    13921 ttacttgtgg ttgtaaaaac cgttgctgat tctttcgccg atacccagct gacggctttt
    13981 gtggatgggt cgatcgataa atatttcgct gtgtcactat cttgatcacg aacgacgaat
    14041 tctgctccag caagtgtttg atctgatgta acgtcaccat ctactttaac aaatcgtttg
    14101 cccccagtaa cgacatcgac tgacggtggt gtttgatcat ttgtatgccc gttatcgaca
    14161 tttgcttggt tagaaaatcc tttggttgga tctgcttttt cgttcaaatg catatagtaa
    14221 acaaatttca gcgtaccacc aggagtgagt gaaggaatat aattcgagtc aactgaaacc
    14281 gtgaatccgt ttgtttgttc agtgacagaa taatttgttg gatcgatttc tttatcccca
    14341 tcatacaaga catacgcata cgttcctgaa gtttcatgat caaatgtcaa agcggcgtca
    14401 tgagtatcaa tgagtttgaa tgtcgtgtac ttgttttgtg ttccttcttt atcagcgata
    14461 cctaaaggaa tattgacaga gatctcatat tggatttttt ctccgattgc gacatctttt
    14521 ccattcaatt gaggtgttgt tttatcaact ttggacgtat catttttgat tgtcttttct
    14581 acaggagttt gactatttgc caagatctca aacggcgtgt ttgtttgatt atcaatcatt
    14641 tccgcattat caggagcttt tacttcttct aaattatatt ttccaacctc taaatgattg
    14701 acgatcaact gacctttttc aatcgttgcc tcggcaaagt cattgttgcc gatgtcataa
    14761 gaatgaccag taatgaaatg tttggctttg gtttgatccg ttgtccaagt gtacaatcca
    14821 tctgtgacac tttggatgta ttttttgacg cttggtcttc cttcttcttt agaaataata
    14881 aattctgctc catttagtgc ttcgttttcg gcagtaccga tttttgtaac tttcaacgtt
    14941 ccatcattac cgactgtatt tttagggtag agatggatag tatctagttc ttctgtcccg
    15001 tatttataag agccatctgc ttgtttgatc atctcatata cagggaaagc taaaaccatg
    15061 tttgcggcag ctgacactcc gtcttttggt tcttctttga tcgtgtagac tgcatctttc
    15121 ccattttgtt ttttaggtaa agataaagtg acatttccat cagcatctgt cgttcctgaa
    15181 gcaactggtg taccaggagt caaagactgg actgcttgtt ttgctgcatc cacggacgct
    15241 cctttatctc gttgcgcata aaattcttga gtgacgttat aaactgaaaa tgaaatatcg
    15301 gctaatcctt ggtattgatc gaattcgctc atttctttcc cgctgttttg gattaaagga
    15361 tcgggtaaat cagtcatttt ctttttatga aggatgactt gagctgctgt ctcctctgca
    15421 aacacttttt ttgcgccgaa gctgtttgtg agtaatggta aaataaggaa aaggactcct
    15481 aacataacgt ttattttttt atgatttttc attttttcac tcctgttctt tttttgataa
    15541 acaaccagat tgcaaagctt gcgaatacca taccaacaac gcctaaaagt gtatttttcg
    15601 tttcgtttgt ttttggaaga aatggacggc tattttcttt tttattgact actttcaata
    15661 tactgtccgc ctctttatcc tcagaaagaa aagttgaaat ggtaaacgga atttctgttt
    15721 cacttaaaat ataaccagaa ggtgcttcga tctcttttaa tcgataactt cctgttttca
    15781 acccggaaat tgaaaaagcg ccatttttat cggaaatcag gtgaagcgca tctgattcgt
    15841 tctttgtcca cttgtatccg ttggctgttt gctggaggta atttcctgct ttgtttttaa
    15901 taaggaatac tgcgccagct aatcgtttat ctggtttatt tgtctcgatt ttgacaaatt
    15961 gcttactccc tgtatataca gagactttct ttgtactgac accaaaacca aaatccagtg
    16021 ttccgttgtt gttgatttcc ttgttcgcct gtgctgtact gcttagctgc atctgataag
    16081 aaatggtcag tttttttcca gcatattttt ccaacgaagg gatcgaaaat aaaacatcaa
    16141 atccgtgagg tttcttgtgt atgacaaagc cttctgtcag cttttctcca ttcgatgaaa
    16201 tcgttaaact attaggtaaa aacgttaatg cttcatccgc actatctgac aattcgaact
    16261 tttgatagtc aaggatattt acaggaattg tcgtatgcaa ggaataagtg attttttcac
    16321 caatcgtaaa atcatttcta ggctcttcta ataccttctc aaaaggtgga tcagggtagt
    16381 cgttttcttc atttttagga tacaaatgga tagttgaaag tttttgattg ttttgtccat
    16441 gtacaggaag aacaactacc atattctctg ccttttcttt gacgacttct ggtactttgg
    16501 attcaatgaa aagatacgct ttatctcttt tttcttgatc tttagcggcc agagaaaaag
    16561 aagcgatacc atcttcgttg ttaagagttg tagttgttgc ttctgcggta aacataccgg
    16621 aagacgcacc gttttttgcg atctctgctt gtgcttcttc taccgttttg cccttttccc
    16681 gtagatggta aaaagaatct gtgacatcat aaacttggaa tgtgacacca tttaatcctc
    16741 gatacgtttg taataaagct ttttcttgtc cgtcatttgg atgatttttc ggcagttgcc
    16801 cgtttgggaa aagcaatttg tgtaaagtaa tctgaaccat ttctgtttct gtttctgttg
    16861 ctacctgagt aaaagctggt ttaaatagta acaagaagag acacatacta agccaaccaa
    16921 gttttttcat atttagctgc cccctctttc ttttttcaaa aaaagatacc aaatagaaaa
    16981 cgcacaacca atcatcccta ctagatagat tcctaaacgg ccaattcctc ccgtttcagg
    17041 taatggtact tttgcctgat tcgtgatgtc taaagaaatc tggttgtttt tggctcctgg
    17101 tgacagaaca gattcatgat cttgtccatc cacttgaatt gacccatctt cgtgtataac
    17161 tatagtaact ggctctttta gaccttggta tccttctggt gtaaaagttt cggtcagcgt
    17221 ataagttcca ggttttaaat tttcgaatag aaaggtatct gtttcttgtc catcttttgg
    17281 cgattctaag tccatttctg gtccctgcag tctgaatttt gctcctttta atgtctgtcc
    17341 gttgtcttct tttttgtgta ccgttagatc aaacgctttt agtcgatttt gatgagtgag
    17401 cgtccataca ttatttgtca tctcggtatt ttttcccgtg taaatgattt ttccatattt
    17461 atcgatttgg aattcataat ttcccggcga agtatcatat ccggcaggac cagctgtttc
    17521 aacgactcga tatttaccag gtgtgagtga atcaaaactg gcaagacctt tttcattcgt
    17581 tgtttggctg tcaattggct gataagtacc atttgcttct tttttctgta gggaaaatgc
    17641 tgctccttta agatttatct ctttgtccgt cccttgcatc gcatacttac gtactgctac
    17701 aggaacttca acaaaaggat tttcaatagt caactggatc gtatcatcgg aagtagtgac
    17761 tgtttttcca tcaatggtta ccgtaccatc agaagcgatc ttgatttccc aagtagtctt
    17821 tttgcttaat ccatgccctt ctggagcttt tgtttctgtc agcgtatagg tcatttcttt
    17881 ttgcaatttg acattttctg gaagagaata ggttccgtcg ccatgatctg ttagtaaagt
    17941 atcaatagaa tctcctgtta atttgaaaac agcgccaata agatcctttt cacctgtaga
    18001 ggaatttttc gttattttca agtttaacgg tgtgaattgt ttagtatttt tccatgtcat
    18061 tgcatctatt tgttgagaat cgtatcctgg tacaggtaat tctttgattg tttggtaact
    18121 gaatgcttga ccttgattat tgtattgagg tagtgataat atctcttgat aactttctcc
    18181 gctatttgca gataatttgt caatgtctgc acgttcccac gtatttgttg tatctttagc
    18241 tggtttaatg attcgaatat atccgttttt ccaagctgca gcatttgtcg tatgttcccg
    18301 ttgaatctca aaagtaactt gatctggacg atcagctaga ttgttgtcaa attcttccca
    18361 taactttttg atgtgaagac tgactccggg agctttagca gatggtatac cgaattcagc
    18421 taattcattg gtatcaatgt ttggctggaa agttgtcctg ccgttcattt gataccagaa
    18481 atttggatgg aagtcctcat tttctgtttg gattctcact tggtaatgga tttggatttc
    18541 ttggtctttt cctaaataga tctgattgct cttgatggta tttccttcta tggaaataga
    18601 tggagtgacc gttgtaggac ttgtccccac actcttgact gaaagtgtac caggctgata
    18661 aatgaatggt tctgcgattg gatcatttat ttgtccattg cttacagttg ctgagatctg
    18721 tacagctttt ttggctaggt attcagagat atctgttgca tgatcagctg attcatagta
    18781 aagatcgcct ttttcatctg atgaaaccat ttgtcgcata cgagactcta cttctgcttt
    18841 tgagagacca gctgccggat cgctttgaag ttggatgcca agaccatgta tttcgattcc
    18901 tcgttctttg agtgccatcg cttctccgat ggttgcgata aacgtactgt cgattcttct
    18961 ggatagattg ttttggtcag gtgcatcata gattcttgag attagagaag tatttcccgg
    19021 ccgatcttgc gtattagaaa actgagttcc gtaataattg ctgcttgatt gtgcgtgtac
    19081 ccgctgtact ttataggaaa atgttggtac accatccgtc agcaaaacga tcactttttt
    19141 atgtccattt ggaacggata gcatgcttcc tgcatctctt agtgcttttt gtgtaaaagt
    19201 accaccattt gtccgtgaag gtgtaatgga ttttacttga tttttcactg aatcaaatga
    19261 acccatctgt actgcaccgt tactgtagct atatccttcg cttgagtagc cgacatatcc
    19321 catattgatt ttgtctgtga taccgctatc tgctaaagta tcgacaaaac gatcgacacc
    19381 aatctttact tcaccgatcc gattattgtc gttcatactt cctgaccagt ctacgaccaa
    19441 tacgagatca agaggcgtga tatctttttg tacatttcca cgagcattca aataaacatc
    19501 aaacaatccg ggtgtacttg tttcctttgc atactttcgt atcgcatagt ctgcttgatt
    19561 accggttcct ccatattcga tatacgaatg ggtccgatca ttaggatctc cattccaaga
    19621 atttatacca tcccattgat ttgttccgtt tttattgcct tgatgatcaa gaacatttgt
    19681 atttcctgta ggttgccaac tggctttagg ataagtgccc tgatcatctg ttgtatattc
    19741 tgtaggaatc gtttgattag atggcacact cacagctggc aaggataatg taggcaatgt
    19801 aaatgggctg acagaatttt cgttttcttt tgatgattct tcttctattt cgtctggctt
    19861 tggtactgac acatctgtat ctttcttatt ttctgtctca tcaataatgt catattcttt
    19921 attatcgacg atcagcttgt ttgcctggct gtggtaaagt gctggatcga ttggaaaact
    19981 cagatcgata gtttgtttag tgtttgatga gatttccaac gtaattttcc cgctatttac
    20041 ctgataagca tagccatctc cttcttttct ttccacatca cttaagtaat tttcgactag
    20101 accaatttct ttttctatct tttcagcact ggtgttattc gcatttagct tgatgttcag
    20161 tgcttttttt ccagactgat ccgaaatgac ttcagctgaa attgtttcta aaactgttgg
    20221 atcatctgta gtgtctgcta ttgcagataa tggcacaaag tttgataaac tcaatattat
    20281 cagcatgaaa ataactttca gtttcttccc tgtggtcgtc atttttcccc tcctttttct
    20341 ttttttctgt tttgacgtga atagtgaaaa ttattaaaat aaacaggcgt tacataattt
    20401 tatttatttt aatatgataa ttattatacg aagggcgcta aagggaatca caccaatttt
    20461 cataccaatt ggtttcattt atgaagttga ttccttcgat taatgagcgt ttcattgaaa
    20521 gaaaagggtt gagggagaaa aacatatgat caggttgttg gaatgaaact atagaaagat
    20581 ggaaaaaatc attcgaattc tgtccatttc tgacaagtgg atgactaaaa aagaacttgc
    20641 caaacgaatt ggtagttcag aatctacatt tgtaaggtat atcgaagaga tcaaaatccg
    20701 ctggggaacg gatgtaacga ttcaatcttc acaaaaattg gggtatcgtc ttgaacattt
    20761 gaatgtacca gcttatttaa atgttctgat ggaaatgtcg caaagttcta caaacagtcg
    20821 tttattaaat gagattattg tcaatccggg taaaacgatt gagtattatt gtgaaaaaat
    20881 ttccatcagc cggtcttctt ttacacgtaa gttgaaacaa tgcaatcaaa ttttagaaag
    20941 ctatttatta aaagtgatcg ttgaccaagg ttttcagtta actagcctta aaagtgagct
    21001 ccagttgcgt atctttgtta cctttttctt tttaagttac tacggaagac gcacgttgcc
    21061 atttccaatc gaaaaaaaga agatcaaaga aattatggtc aagaataatt gtcagatgaa
    21121 tttgtttcag gaagaaagcc catatgagca atctttcttt attatgtatt ttgttgtgca
    21181 tctcatgaga gaatcccaag gaactccatt tgaatggaaa gctggagact cttatgtaca
    21241 gttgataaat atcgataaaa aagacttctt aatcttgaaa aatctcttag gaaaattgaa
    21301 gtacagcagc tatataaaag tagtgaacta ttttgtcaat acgatttttt cagaattttc
    21361 ggagaaagaa aaaaatgaaa tcagtgagca gatacgaaaa aatatgtcct actgttcgtt
    21421 ttcatccgct gattgcaaag aaaaaaacga agaatatgtt gttcaattat taacgcaaat
    21481 ttattttttc tcccgtattt tcccatacga tacgactcat ttgacgatcc gtgcaactta
    21541 ctttgcacag cagatgcaac accgccagat acgtctatat gctggatttc gtgcagaact
    21601 tcaattttat tccactctac tgaatcagaa tctgatttat tatttatcta gctatatctt
    21661 ttggatgctt atcggtaatc ctgaaattca ccattatact tctgataaaa aaatactgat
    21721 tatcagcgac ttaagtcttc gacatagtca atatattgaa gaatatatca gtgatattct
    21781 tgctgtgcat aaaattcact ctgagacaac tgctattact gaagatcagc tgtcgaaata
    21841 caatcttctc gagtatgatc tgatcgttac gaatcaaccc attttgaatg cccatgttcc
    21901 tcatatattg attgatgata gtgtgtcatt cgcaaatgaa gaagaactca tccgcttatt
    21961 cgagttatga ataatcaaaa aacagctatg tataaaccac cctgataaaa atttcaggac
    22021 aaatacacat agctgtttct ttttattgta ttccttcagc aatccaacga gatttatagc
    22081 gaaagtcttt taacaactct tcttttgtcc aattatttgc aatgagatcc gtcaaagtgt
    22141 tcattacgag ggtcatggaa aagtatagga aactaactgc ttcttccgac gattgaatgg
    22201 agaaatgatt gattcttaat aattccagcc atttttcgtt cattggagaa tcagccgata
    22261 gttctctacg tttggttgtc tgctgatcat ttcgctgggt taacaagtat aacctttgcc
    22321 aatagatact ttcgtgatct aagtcgcagc accactctaa atatttttcg atccccaaaa
    22381 agaaatgttg tttgttttcg ctaatgaatt ttaagatatc ttgatggact atgtgagaac
    22441 tgcttttgat cgtatacaaa taagcatctt ccaaatcttg aaaatattta taaaaagcac
    22501 cgcgcgacat ccccatcttg tcaacgattt ctgagacttt gacttggctg atgtgctgtg
    22561 agcaaaatat ctccagtaat aggtcatcga ttctctgttt ctttgcgttc gataaattga
    22621 aaaaagtttc ttttggcatc cacatctctc ctttatctct gattatacgt ggatagccct
    22681 tcattgtcat gaaggattca ttccttcttt ttctcttctt ctgtcaagta cccatcttcc
    22741 attcgataaa cgcgatcact ccattgaatc atacggacat catgagtaac cataatagtc
    22801 gctttttgtt tctcatgagc ttctttaact agtaatttga cgacttcata tgcatgatct
    22861 gtatccaaac tagctgttgg ttcgtctgct aagatcaagc ttggctcatt atataaagcg
    22921 cgagcaattg ccactctctg tctttctcca ccagaaaggt ctttaggata actattttta
    22981 agtgactgga tatctaaaga ttgcagcaag gaatcgattt ttgttgaatc ttcttttttt
    23041 gaagtaactt ggtcaactag ttcaaattgt tcctttaccg ttaaaaaagg aatcaaatta
    23101 gagctttgga gaataaatcc tatttcttta aagcgtaaat ctgctcgttt tttttctgga
    23161 agctcagtta gtgagtgacc gttgatcact atttctccgg aagtcggtgt ttgcaatcct
    23221 cctgaaatgg taaggaaagt acttttacct gaaccagaag gaccaatgat gctgacgaat
    23281 tctccttcct ttacataaaa atcaattgct ttcaaagctg agacctttgt atgaccagaa
    23341 ccaaatgttt tggtaacttt tttcatcgtt aatatttttt tcatttttat taacctccta
    23401 ttgctgtaat tgggtctact ttggttatcg tacgtatcga aaacaatccg cctagcattg
    23461 cgacaatgat caaaatccca ctatatagca accattgtga ccaaaaaaca gcaaaaggca
    23521 tcgcgcttgg taaaatcaga ctagtcaaat aagcaaacaa aagagcaagc agaacgccta
    23581 ccaccccaac aataaaggac tgtgctacta aagatttagc gatgaagaaa tttttgatcc
    23641 cttgtgcttt cattactcca aaaatagcag tcttctgaag tgtcatcacg tacatgaaaa
    23701 taccgaccac ggcagcaacc actaagaaca aaaagtatat catcgcattt aaggtcatat
    23761 tttgggcaga atagccagga atactttcaa tgaatgtccc aatagttaat aactgtagac
    23821 ccttcgatgc tttttctttc gaaattttag ctgaatcctt tattacgatc ccattgatcg
    23881 gctgttcttc ttcagaagca aacggctgtt gtccatactt caaagcagtc cacgtatcta
    23941 gggacgcata gatgacggga gaaactgtgt aataagtttc aggaaagata ccgacaatcg
    24001 tcaaaggatc gtcgtaactg ccaattttga tcgtatctcc aattttatag cctgaatcag
    24061 ccagattttg agagatgatg atttcattct ttgttttaaa ttcatgccct ttcgtgagtt
    24121 ttggtaataa aaatgcttct ttcgttgtgc cgaaaactgt aacattttct ttgttttttc
    24181 ctttgattgc tccgctgtac aatccgattg gtgctttctc tcctccttca atgtatttca
    24241 gatctcctct tgttaattgt gaagctgcaa atacttgatt tgcatcctcc gacaaaacaa
    24301 tctcttgtgc gtcccaatca tcgattgctt ttttaaactc ttctgaaagt ccattcgcta
    24361 gtcctgacaa catgaatacg acatacgcaa tcaagaacat aataccgacg atcaagccat
    24421 atcgtaattt agaatagcga atttctttga tagctagaaa catttgtttt tcctccctat
    24481 gatagattga tagtgacaaa atgtcacttg ttgaatagtg taactctaaa gtgacaattt
    24541 gtcacttgtg ttgttttttt cttatcaata aattgtctaa gacatctttc gataaaacct
    24601 taacatgagt cataaaaaat ttatttaagc cttatttatg ctttccatga taaactaaag
    24661 tgaccaaatc aatgaggtgg gaaaatgatt aaactattag tagtagaaga cgataaagta
    24721 ttatccaata atataaaaga aatactcgct gcaatcggcg agataacaca agtttatgat
    24781 ggtagtgaag gactgttcga gttggaaagt ggagtttatg atcttgcaat cttggatttg
    24841 atgatgccgg aaatgaatgg atatgaagtg ttagcaaaaa tacggaaaga aaaaatacag
    24901 actccagtat tgattttgac tgcaaaagat agtttggaag ataagattga aggatttgaa
    24961 cgaggtgcag atgattatct aacaaaacct ttctatcgag aagaactgat catgcgcgtg
    25021 aaagcattat tgaaacgctc gctaggtctc tttgatgaaa atgttctgaa gtataaggat
    25081 atcagttgtg atttaaaaag caatgaagtc ttgtataaag aacaagtttt gcccatacaa
    25141 ggaaaagagt ttgaattgct cgtttatttt ttacaaaata agggaatcat tttgacaaaa
    25201 gagcagatat ttgaccggat ctggggattt gattctgata cgacgattac agttattgaa
    25261 gtttatatga gcaacttacg aaaacatctg cgaagtactg gattggataa agaaatcaaa
    25321 accttacgta atgtcggtta tatactgcaa agggtgtgat gcaatgaatg gagatattac
    25381 acgaaagcaa cgtagtcgct tttttgcgac aaatgtagca gcatttgctt ttatcttttt
    25441 tcttttggga ttcattactt tacagatatt aaaccaatct gcatacagag aaacagatct
    25501 gtcattagag aaaataaatt ttgattctcg aacagtacaa ttagagatac aaagatatca
    25561 gcaaggcgat ccctttttaa acccgactca aacggaacaa aacagaacaa acatggaaca
    25621 gccattaatg gaaccatcaa atgaccgttt taacactcaa gtgatcttgt ggtctaaaaa
    25681 tggtgagata ttgaataaag cagctattgg tgggcgtttc aaccaaatca aagaattaaa
    25741 aatggatacg aaaaatctga ataccatcca aaatattgaa ttaaatgaag acagtggctc
    25801 atctgccctc tctttccgtt cgattacgaa aaaagcggag acgaatcaag atggcgttgc
    25861 ctacatccaa attttagaaa atacaaatca aatcaagaat tcattagcga cttttcgcac
    25921 gattatgatt ttgtgtatga ttgttttttg gattctctct attggtatca gttattactt
    25981 gtctagtcta agcatgcgcc ctattattct ttcttggaga agacaaaaag aatttgttga
    26041 gaatgcttct catgaattgc gcacaccgtt aacgattatt caaaatagtt tggaacatct
    26101 ttttaccaag cctaatcata ctattattga agaatccgaa agcatcgctc aagcattgtc
    26161 agagacgagg cgcctcactg gattgacttc ggatttgctg acaatcgctc ggaatgattc
    26221 tgatcagcag ctgctttcaa agcaaatgat caatacacaa gaatatatcg aacaacttgt
    26281 taaaccattt caagagatgg ccatcataga tggaaaagag tttattctcc ataacgatgc
    26341 aacattagaa gtaccaattg atgaaaaaaa aatccatcaa gttttggtta ttttgctgga
    26401 taatgcatta aaatatacga atccagaaga taagatcatt ttggattcat ctgttaacca
    26461 taaagaatgg ctgattcacg taaagaatac tggcccttct atcagtgaag aagatcaagc
    26521 aaggattttt gatcgatttt atcgggaaga tcaatctcgg gcgaaagaga ctggcggata
    26581 cgggcttggc ttggcaattg caaaacaggt aatcgaacag catcatggac agatttctgt
    26641 atccaattat cttccacaag gagtcgattt taaagtccaa ttgccgttga agcctaaaaa
    26701 ataatgctta tccctaaaaa agggctgtga caaaaatctt gtcacagccc ttttttgttg
    26761 cgaataaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt ctttaagctg
    26821 accacttctg tcacaacctc tttagcttac gcttacgatt ttttattgcg gtcttcaatg
    26881 tgtacatcac cgcttgtgtc aatatccaat tcttctcggc taacatcttc tgtcactttt
    26941 tcaacatctt catgttcttc tttatgaatc ccaacttctt cacgaataac tgtatgtttg
    27001 cttacatcta cttgctcttc tttgattggg atagtaatcg tgtcatcttc caatttttcg
    27061 tctgttccct gtgaagattg atctgttact ggtttgcgtt cgatgacgat ttcttcacgt
    27121 ttgaccggta cttctaccgt ttcagtatcg ttgaccacat gtttgtggat gtcgacttct
    27181 ccagttgtca catcatgtgt atttacatct aatttttctt cttttagttg aattgtatca
    27241 tcatctagat ttggtttgcg atcgatgtct tcagtcttgc ttgtacccat tgtatcagtc
    27301 tcgccaggta cgtccatcgg atcagttcct ggtgtcatat tcaatggatc cgttgtattt
    27361 tgaaagcctg tcgtgccacc tacgtccatt ggatctgttc cagtgccagt ttctaatcca
    27421 gtccccattg tgcttgctgg gctaacagta tcttgtgtat ccattgtatc ttctgttgtt
    27481 tctggctgac gatagccttt tactgtgatg acaaattttc catcagaaat atctcctcta
    27541 tattgatata aaggatcatt ttctggtgta gccgtctcag aatcataggt atcaaaagaa
    27601 aaagtatctt ttattttttc ccataaagaa cggtcttctt caccatccat ccgattttca
    27661 tctgtttcaa catctatacc agacaatccg tcaaatccta gtctagatgc tgcttcatca
    27721 gtagtataaa taacgatatc atctcgttca tacccttcgt tacgcaaccg ttcaattact
    27781 gataatgctt cttccctcgt actatagctt ccgatgaccg ttaaattttt ctcttccatg
    27841 taaattcctc ctagcaaata gattt
//
LOCUS       DADVXM010000028        27846 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.029, whole genome shotgun sequence.
ACCESSION   DADVXM010000028 DADVXM010000000
VERSION     DADVXM010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.029"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..642)
                     /locus_tag="KB927_001315"
     CDS             complement(<1..642)
                     /locus_tag="KB927_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6840243.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGG"
     gene            637..903
                     /locus_tag="KB927_001316"
     CDS             637..903
                     /locus_tag="KB927_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6840244.1"
                     /translation="MHRTFGSRGCPTLHLADRYAERKTPTLCFAFSARTRQAGIPLED
                     IKDFLGHKDVSTTQVYAHISPEVKKRSMNQLENYIEEQIKKHSN"
     gene            complement(1079..1648)
                     /locus_tag="KB927_001317"
     CDS             complement(1079..1648)
                     /locus_tag="KB927_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6840245.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYKTLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1722..3011)
                     /locus_tag="KB927_001318"
     CDS             complement(1722..3011)
                     /locus_tag="KB927_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840246.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFYFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLIKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQALAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            3365..4213
                     /locus_tag="KB927_001319"
     CDS             3365..4213
                     /locus_tag="KB927_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBB6840247.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4358..5299
                     /locus_tag="KB927_001320"
     CDS             4358..5299
                     /locus_tag="KB927_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBB6840248.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5289..7460
                     /locus_tag="KB927_001321"
                     /pseudo
     CDS             5289..7460
                     /locus_tag="KB927_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7572..9743)
                     /gene="copB"
                     /locus_tag="KB927_001322"
     CDS             complement(7572..9743)
                     /gene="copB"
                     /locus_tag="KB927_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBB6840249.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9763..11949)
                     /locus_tag="KB927_001323"
     CDS             complement(9763..11949)
                     /locus_tag="KB927_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBB6840250.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(11949..12158)
                     /gene="copZ"
                     /locus_tag="KB927_001324"
     CDS             complement(11949..12158)
                     /gene="copZ"
                     /locus_tag="KB927_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBB6840251.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12171..12611)
                     /locus_tag="KB927_001325"
     CDS             complement(12171..12611)
                     /locus_tag="KB927_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBB6840252.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12685..13224)
                     /locus_tag="KB927_001326"
     CDS             complement(12685..13224)
                     /locus_tag="KB927_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HBB6840253.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(13839..15305)
                     /locus_tag="KB927_001327"
     CDS             complement(13839..15305)
                     /locus_tag="KB927_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6840254.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(15616..17697)
                     /gene="cadA"
                     /locus_tag="KB927_001328"
     CDS             complement(15616..17697)
                     /gene="cadA"
                     /locus_tag="KB927_001328"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBB6840255.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(18221..18580)
                     /locus_tag="KB927_001329"
     CDS             complement(18221..18580)
                     /locus_tag="KB927_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBB6840256.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(18610..18951)
                     /locus_tag="KB927_001330"
     CDS             complement(18610..18951)
                     /locus_tag="KB927_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840257.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(18948..19622)
                     /locus_tag="KB927_001331"
     CDS             complement(18948..19622)
                     /locus_tag="KB927_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6840258.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(20675..21973)
                     /gene="asnS"
                     /locus_tag="KB927_001332"
     CDS             complement(20675..21973)
                     /gene="asnS"
                     /locus_tag="KB927_001332"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBB6840259.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(22013..23203)
                     /locus_tag="KB927_001333"
     CDS             complement(22013..23203)
                     /locus_tag="KB927_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6840260.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(23224..23751)
                     /locus_tag="KB927_001334"
     CDS             complement(23224..23751)
                     /locus_tag="KB927_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBB6840261.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(23798..26587)
                     /locus_tag="KB927_001335"
     CDS             complement(23798..26587)
                     /locus_tag="KB927_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBB6840262.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(26734..26934)
                     /locus_tag="KB927_001336"
     CDS             complement(26734..26934)
                     /locus_tag="KB927_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6840263.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(27386..27706)
                     /locus_tag="KB927_001337"
     CDS             complement(27386..27706)
                     /locus_tag="KB927_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840264.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
BASE COUNT         7825 a         5910 c         4887 g         9224 t
ORIGIN      
        1 tccaccctta gtatttcctt ctggatcgtt tgtcgcacgc atcatgacgt atactttctt
       61 attagggaaa tcacgcatat tgaaagatac atgatagcca acatttccta aagtattata
      121 agcttgattt acgtctggtc tataaatccc atcagctctt actctagcta gttcttttcc
      181 agtattgtag tccataatga aaatatactc gtatttataa ttagcaatgt gccatccagc
      241 tacatgcaag tttgcgtttt cgatttctcc gaactgatca atgtgggcgt aatttgttcc
      301 atctgtcagc gtagaatttg cagcacctgc tcgagttgga tcaattactg gtttatcctc
      361 cgaagtagtt ggattatcat ccgtaaaacc atgagccaaa tcataggcta gtttttcttt
      421 acttacaccc atttcagaaa gataaccgta aggatctgta tgatcgcccc aaatattttg
      481 tgttacccat aaatgcgatt tgattcctgg ttggttataa ggagtgtcta atgttaatgg
      541 aataccatat ttcattgctg aatctcttgc caattcaacg tatactttat agttcttttc
      601 aaaagtttct ttatcatgtg tgtgttgtaa ctcgatttgc acaggacttt tggctcacga
      661 ggttgtccta ctctacatct tgctgataga tatgctgaaa ggaaaacacc aacattatgt
      721 tttgcttttt cagctagaac gagacaagca ggaatacctt tagaagatat caaagatttt
      781 ttaggtcata aagatgtttc cactacacaa gtctatgccc atatttctcc cgaagtgaaa
      841 aaaagatcaa tgaatcaact agaaaactat atagaagagc aaataaaaaa gcactcaaat
      901 tgagtgcttt tttaagctca ctatcactaa aactatcact aattttattt ataagcgaac
      961 atgtttctat cactgatttt ttaaatctag cgaaaaaccc ttatcttaaa ggcgttcgtt
     1021 caattctttg gcaaggtctt caaagcctgg cttgcctaga agtgcgaaca tggttttctt
     1081 atagctcatg tagaaaaatt ttcttgatga tgattttatc catcaattga gattgactgt
     1141 tttgctctcc tatgatttca gctatgattg tccgattttg cggttttctt cttaactggt
     1201 agttgatttt cccagtttcc atcaactcgc taagcatatc cacgactccg ccaaatccgg
     1261 tctttttcgt aataaaacct agtgctacca ttcgttcatc tagatttttt gctgtaatcg
     1321 tcacaccagt aatgagcgag tgctgtaatg tttgggccag ctcttccatc ccttcagcat
     1381 tggatacgac ggaagctgtt ttgttaatag gttcttcgtt tatttctttt ggttctttcc
     1441 tctccacttt cactgtttga cgaaggacat ctagttcttg caagagcgtt ttgtattgtt
     1501 cttgggtcag catcacgcca gctacttttt cacgattaaa tatatatacg ccagttcccg
     1561 cgtctcgcgc ttgagcaaat acatccatcg gcgatcgttt cacttctgtg atcgaagatg
     1621 tgggaacttc taatttcttt aattccaatg gatttcctcc tttactaatc gctttttatt
     1681 atagcacaga ctgacttgtt ttgatctttt ttccaaaggt tttatcggtt tttgcctaac
     1741 cagtaattga tatcggtaag aagtctttcg ataccaaatg aaggatggta cagatacgtt
     1801 ttttgatctt cgttatggtc tagtggaaaa aaatgatcgg tgatcactag atctgcatac
     1861 cgaggcggct tatttcgagt acatacatgt atagagatcc gttttcgatg tcttagcgtt
     1921 ttgttcagta ccccagcaag tcttcttgct tcttggtgtt catagcgaaa aaaaaagacg
     1981 attttcactt caggagggtg gacatctaaa taccctcgtt cctggagtgt tttcagtaaa
     2041 agcatccccc actctactgc ggggtgtgca agtgcttgtt ggatcgctag ccgaaattga
     2101 tatagtttat ctttggaatt gggaaatttt tctaatgttt cctgataata acgaacttct
     2161 tctatcagcc ggtcatggat accaattacg taacgaagcc attcttggta aagtactttt
     2221 atcagctttg atttgctttc gctctcaaat tcgctattca gccaaaacag cgaatcaagc
     2281 ttttcagtca caatcgtcaa tttccgatag tcttgtgtct cttctatccg tttccaccgc
     2341 ttttcagtaa tctggttaca gctcaagcgc aaaattgcta gataattttt ttcttttatt
     2401 ggcaaaatct gctcctctct aaatagcaat tcaggaaaca attcaaagaa tagtgttcga
     2461 ctgtctccta aaatctcgat ttctgccgga tcctttcttt gcttcaataa ttggatgaac
     2521 atctcagaaa aggactgctc tccatcatct gcaaaaaaat gcggaaaatc tttcaaaaag
     2581 taaaacagca gatatcttac ttttctttct gaaccaaaga tctgtgcttt tttataagaa
     2641 aaagaaaggt ggtactcgcc aaaccacttt ctcaatcgct cttgcgtaga acgatcgtac
     2701 ttctgctcgt aaggttcatt taatagcaga tttttcagta aacaaaacgg gggtgattgg
     2761 atcagaaaaa caaacaagag ataaggttcg ctatatcctt gatcataaac taactgaacg
     2821 gttttcttat gaagaatcag ctgaatggga cagtcgcttt ccgccaaacg tttcagatgc
     2881 cgatccactg ttttaacatc gattttcagt tcttcagcta aatcagcttt tcgccagatc
     2941 aaatctttca ttagattgat tagtgaaaat aaattctgtg cattttttga taatagtttt
     3001 tgccatctca tcgatcattt ctcacctgat ttctaaacat attgtttgat caaaatgagt
     3061 tcactcctaa aaagataaaa aactcccttt ctatttattt aaatacgcaa atcttcctca
     3121 ttatttttta ttttactcaa tttaatcgta ttctcatttc aaaacgaatg tactttaaaa
     3181 aaacataata agatcacttt gcttgtagga tgtattccct tccattacaa tgaaataaat
     3241 agcgatttta tgagaaggtg atgtgaaaat ggaagaaaaa atagaagaat ccaaacaaaa
     3301 aatcgatcag ttgatataag aattagaaaa agcggtcatc ggcaaacgtt caactatcca
     3361 attgatgatc gtggccctat tagcaggtgg tcatgtctta ttcgaagata ttcccggtgt
     3421 aggtaaaacg ttactggtca aagcactagc aaaagctgta cagggaacct tcagcagagt
     3481 ccaatgtact cctgatctgc tgcctagtga tattcttggt ttttccgtat acaattcaca
     3541 atcaaaagag tttgaatttc gtccgggacc gatctttacc acgatcttgt tggcagatga
     3601 gatcaatcgt acgactcctc gtactcagtc agcactttta gaagcaatgg ccgagaatca
     3661 tgcaacgatc gacaacaata cataccctct agacaatcat ttttttgtct tagctacgca
     3721 aaatccaatc gagtacgaag gaacatatcc tttgccggaa gcacagctcg atcgtttttt
     3781 attccgacta caaatcggtt atccttcttt tgatgacgaa cttttgctac ttttggataa
     3841 attcgaaaaa gtgttggata acttaaatga agtattgaac agttatgaaa tagaagaaat
     3901 aaaaacaaat gtggcgaatg tctttgtcag tcccgaagtg gcatcttatg ccttgcagtt
     3961 agtgtcagca acaagaagtc atgctgccat ccagcttggc atcagtccac gaggaagcct
     4021 ttcctttatt caggcagcaa aagcttatgc tttaatccat gggagaaatt acgtcacgcc
     4081 caaagatttg caggatttag ttccttacgt gttttcccat cgcctgattt tttacgatcg
     4141 ttcattgaag gaagacgaaa agaaacaaat cattcatact cttgttgcac aaattcctat
     4201 tcctgtgagg tagattgagg tagacaatgg aaaaaatcaa agattatttc attaattttg
     4261 tgttatttct ggtatatttc atcattgtgc tttttgctct tgtattcaac aattctttag
     4321 gctggttctt gttggccttt tttactcttt atgtatcatg gagcttgatt tcattaagca
     4381 gctttctaaa gaaactttcg gttacttgta cattgcagcc actcgtttat cgcaaaaaaa
     4441 gtatgcaggt tattttttcc atagcaaaaa agagaacttt ttctttacct ctccctcgtt
     4501 tacaaatcgg cttcccagca atctttgcag aaaaaaacaa gagattttga ttcttacaaa
     4561 taaaccgcaa gaagtccaat tgctttggca gccaaaagaa agaggatgcc atgaaacatt
     4621 aactgtcatt tttacagcct atgatagtct aggacttttc agaaaaagtg caaaaagaga
     4681 gatctctttt cctgtgactg ttctgcctgc tttttgtaag attcaagcag aaaaattaca
     4741 gagagttctg gaaaaaaaac agcagctgaa cgcgtaccaa agaggtcttg attttcggga
     4801 acatcgcgct tatcgtccag gtgattcttt caaccgaatc gattggaaat tgtctgctca
     4861 tactcaagag tggttatacc gtgaatacga ttatcaagaa gaagaatgtt ctcctctttt
     4921 ttgcttttgg ggttcgccca gtccaaaatt tgaacctctg ctagacttgt atttttcttt
     4981 atggcatttg agaaaagaaa agcagccgga acttctgata ttaggcaacc gcgcctttca
     5041 tggcaaagac cccggtcata cctattttgc ttctttggaa gctggcgatg agaaagcttt
     5101 tttcgcacac ttgaaaaaat atgcaaaaaa acaaatcgtc ctctttgttc ctgagaattc
     5161 tcctgaagtc tcagaagcta ttgaaacatt gtcaaaagat cgaacggctt atcttgttta
     5221 tttcgtagaa aaacaactca tggtccaaga aaaagacaag atatgttcat tgccaggagg
     5281 tgaatggatt gacgattaaa cgggaaaaat ggctgcgtgg cgtttactcc tttgtgatac
     5341 taagtgtagg tgctccgata tttgtagtag ctaatcaatt gcaaaacagc taccttctta
     5401 tcctaactat tggtgtccta tgccttattg tctgctgtat tcctaaaaaa tgggtacgtt
     5461 tgctgctttc tttgccagta atgataggtt gtttgttttt atattttcct tcgaagacat
     5521 tttccatatt atggatctta cagttttttt cgtcagttac agaggaattc ttccatctat
     5581 cccaaggtaa actttattat ttgccagaaa agacagcttt ttttctcata atgttgctga
     5641 tctatttatt tattacattg accgtggatt acgactattg gtacgcaccc tttctttctt
     5701 tgatggctta cttcatgatg cttaccgttt ttcggaaaaa agatttactg tacgaaatga
     5761 ttgcggtagt aactgttttg ttcgtgtatc tggcagcaag gcaatttttc tccatccggt
     5821 tgttgtcggg aaacactcga ttccagtcat tgactacagt tctgcttatt tgtttcttaa
     5881 cttttagcgc tatcttgcct ttatatcttc cgaaagtaca ccaatctctc gaggaaacga
     5941 gtgaaccgat ccgagaatat cttaatgatg aagggcttta tgacacactc catgagtatc
     6001 aattaaccgg aagtgcaaga acaggcttca gtgagaatga tgaacagctt ggtggacctt
     6061 tatatgataa tggcgaagtt gtttttacag cgaaccaaaa aggaaatggc tattggaaga
     6121 tcgaaaataa aaatcattac accggttctg gatggataga agatcaggac gcacccatcc
     6181 aaccaatcca agaattccct gttgacatca cgagctacca aaccgttata gaagacaaag
     6241 aaaacattac attgacccta aaaaaacaag ctttcttacc ttatccttat ggaaatacta
     6301 ccttgactga tttttcatta gctagtggac aaacgcttta ctatttgcct gaaagccagc
     6361 gattcattcc tgtcccgaat gaatcgacac gttctgcaac tttacaaaca gaaaggttag
     6421 tttttacgag agaagaatta aaaagcagtc agttaaaagc tgatgattta gaaaatcagc
     6481 agacaaatct tcaattgcca aaaagtttgc ctaaacgtat tgaggacttg gcggtcgaat
     6541 tgaccaaaaa tgaagcaact ttaattcgta aagtcgaagc tgtctaacag tatttaaaaa
     6601 caagcggaaa tttccgctat tccaaaacgg ataccgggca tactccgaaa gaacacgatt
     6661 atgtggatta tttcctcttt gattcaaaag tcggctattg tgacaacttt tcaacttcta
     6721 tggtcgtcct tcttcgaaca cttggtatcc cagctcgctg gacaaaaggt tttacaaatg
     6781 ggctcagaac aggcacagat aatcaaggga atgaggaata cagcattctc aatagtcatg
     6841 ctcattcttg gccagaggta tactttcctg gatttggctg gcttccattt gaaccaaccc
     6901 cttcatttgc caatccaatg ggttcacaac cagttgctga aacaaccgaa accgtccagc
     6961 ctgctatcga acaaccaaat gaaagcgaaa atatggcaga aactatttcc agtgagagat
     7021 ctgaggtcat tccatcagaa gaaacaacac tcacaccagc ttataaaatc gtcttattca
     7081 gccttggagt gtgtttatcc gtcttgttgt tctttctatt gttattcaga aaatctctgc
     7141 gctggacaag ttatcttatc tatcttcatt tttttgcttc tactaatacg attgcatatc
     7201 aaaaacttct taaccctttg gaaacattgg taccgcgcaa acccgcagaa tctttgcagg
     7261 aatatagcct gcgaatagaa caagaattca agctagatct gcgtttcatt cgattaacta
     7321 ctcaatatga agcagaaata tatggacgac aagcagatcc ggtaaaattc gataaaaaaa
     7381 cctatttaga aataacgcgt ataataagaa aaacggtata caaaaaaatt ctgacaaaag
     7441 ggagccgctt caaaaaataa gataaaattt ctggagaatc tacttctgga atgccgagaa
     7501 ccagctgatt gagtatcgat tactcgaaaa aaaggttgtg acacgttttt tgtcacaacc
     7561 ttttttcatt attatttgat tttcaatgtc aaagcattta gagctacaac taccgtactt
     7621 aacgacatca agacagcacc aactgctgga cttaatatga taccaattgg cgcaagaatt
     7681 ccggctgcta gcggaattgc aagaatattg taacctgccc cccaccagag gttctggatc
     7741 attttctttc gcgtttgctt ggctagatca agaaaatgca aaatatcttt tggatcgctg
     7801 tttgtcaata cgacatccgc agaatcgatt gcgatatctg tccctgcacc gattgccatc
     7861 ccgattgaag cacgggctaa acttggcgca tcattgatcc catcacccac catgattact
     7921 tttttccctt ggtcaaggta tttctggaca acagcttctt tatcatctgg taataaaccg
     7981 ccataatatt cttcgatccc taaataatct gctactgctt gggcagcgtt tttattgtca
     8041 ccagtaagca tgacaggagt gatttttctt tctttcaatg ttcggataaa ttcttttgct
     8101 tctgttttta ctacgtcacc taaagcaacg attgcagcta gatgattttc taaaatcagg
     8161 aagctgatgg tatttccttg ttcttggtaa ggtttcaata atgcttgttc tacgtttaat
     8221 ccgagacgct caacttcttt ttcattaact attttcactt gttgtttttt gactgttgcc
     8281 tctagcccga ctcctgaaag attttttaga ttttcagctt gataaggctt gatttcatgt
     8341 tctttcaaat aattcataat gccaacagcc aatggatgat tggcattcgc ttccaaggct
     8401 cctagatatt gaaggatttc atttttattg aacgcatcat caagtacttc gacacccgtt
     8461 acagtaaatt ttccttctgt tagtgttcct gttttgtcca gcatgatcac atctagatca
     8521 ttggcttgct ccagtgcatt gcggtttttc aaaagtaatc cgtttttagc tgctattgat
     8581 gtggagcgag caacaactaa tgggatagct aaacctagag catgaggaca ggcgatgata
     8641 aagactgtta ccatacgttc taatgcatta ggaagatctg tcaagaacaa ccaggcgatg
     8701 aatgccagga tacccacaat taatgcgaca taaaacagcc attttgccac tttgtcagat
     8761 aatgactcta gcttggattt ttctccttgt gcttttcgca ccatttccat aaccttcgct
     8821 agataaccat tttcaccagt tccagttact tcgatttcga tcgttccatc cccattgata
     8881 gaaccgccaa tcactttgtc attggcttgt tttttgattc ctcttgattc gccagtcaca
     8941 gctgattcgt caacaattgt ttcacctttc aagattacac catctgttgg cattttatca
     9001 ccagaccgga cgatcaaacg atcaccttcg tttacttctt tcaatgaaac tgtctcttct
     9061 tttccatctt tcgtcaagcg tttcactgat tctggcagta attctgctag tttttgtaaa
     9121 gcattgctgg cattcgacac agcattcatt tcaatccagt gacctagtag cataataacg
     9181 atcaaagtag ccaattccca gaagaaatcc atgacgtgtg tatgtggatt gagcagattt
     9241 gcgataaacg aatagacact ataaatatat gcaactgtaa tccccatcgc gatcagtgtc
     9301 atcatagcag gacttttttg tttcaattcc atcttagctc cacttaaaaa tggctgaccg
     9361 ccatagataa atagtatagt tgctaagatc aatacgagcc aatcagaacc aggaaacgtt
     9421 acttgaaatg gaaattccat tcccatcatt ggtgaaaaaa gaatgattgg gatagctagg
     9481 ataagcgata gccaaaattt ttgtttgaaa ttccccatgt gcatggaatg atccatgccg
     9541 ccgtgttcgt gatccatgtg catcgaatgg tccatttgtt tgctgtttgc tatatctcca
     9601 tggttatgtc ccatgtgcat ggaatgatcc atctgactat ggtcatgttt catctccatc
     9661 tgtttttcat gagattctgt actttctttg tttactactt cttttttatg ctcatgtttt
     9721 ttctccatat cgttcccatt catttttact ccatcccttc tcttactttt tcatgtgtcg
     9781 atttaagctc agggagttca acaatacact gacggaacta aacgccatcg ctcctcctgc
     9841 aatgattgga ttcaaaaagc ctagtgcggc aaaaggaata ccaatcgtat tatagacaaa
     9901 agcccagaaa agattttgtt tgatttttct caatgtcaac ctagacaact cgattgtttg
     9961 tgcaatggat gccaaactgc tattcatcag cgtcacatcg gctgtttcca tcgcaatgtc
    10021 cgttccactt cccattgcca taccgacatc agctaatgct aaggccggtg catcattgat
    10081 tccatcgcct gccataccga cttttttgcc atctttctga agtttttcta cgtaggctgc
    10141 tttatcctct ggaagtactt cagcaaagat atgctttgga tcaataccaa cttgtttacc
    10201 aatcgtttcg gctgccagtt tgttgtctcc tgtcagcata aaaacatcta atcctttatt
    10261 ctggagctgc ttgattgctt gtttggcttc tagtttgatt tgatcagcca cggcaatcca
    10321 cccgatcact tgcttttcat cagctaaaaa catgactgtt tttccctgct gttctaattc
    10381 taacgcgtgt tcttggtatt catcaaatga taggttcaat tcaattaatc gtttacgtgt
    10441 acccgcaaaa tagcgtactc cattaatcgt accgctgatc ccagcacctg ggtgggctgt
    10501 aaaatcaatc atatcgtatg ttgctgcttc ttgcagtttt ccgtattcca cgattgcttt
    10561 acctagtgga tgttcagaag cttgttctaa agtataaaaa atagatagga cttcttttga
    10621 accgactaga tctgtaactt tgggctttcc ttctgtaatc gttccagttt tatccaaaac
    10681 aatgctgtct aagtgagcag ctgcttctaa tgcttctccg cctttaatta aaattccatt
    10741 tcgtgcacca acacccgttc ctaccataat agctgttggg gtcgctaaac ctaatgcaca
    10801 tggacacgca atgactaata cagagacact atggatcaat gcgagttgcc aatcaccagt
    10861 gatcaaacct gtagctatga gcgtgataaa cgcgatgact aatacgatcg gaacaaaaat
    10921 ccctgagatc cgatctgcga ttttttggat tggggctttg ctcccttgag catcttccac
    10981 catttgaatg atttgcgcta atactgtctg cttgccgact tgtgtgactt ccatgtgtag
    11041 cagaccattc gtattgattg tcccgccaaa aagcgtgtca tccggattct tttctacagg
    11101 aagattttca ccagtaagca tactttcatc tatcgcactg cttcctgaaa taattcgacc
    11161 atctgctgga atctgctcac caggacggat gactagttga tcaccaacga ctacttcttc
    11221 aatcgctaac gtttcttctt tcccgtttct tatcacttgg gcggtttttg tttgaagaga
    11281 catcaattgt ttgattgcat tacctgtttt cgtttttgct gtatgttcca aatatttgcc
    11341 gagcaaaatc agcgtgatga tcatactgct gctttcaaaa taaagatctt gggggtgtcc
    11401 acggaaaaat ccgttgtaaa tgctcaatgc aaaggcagcc gatgttccaa ttgctaccaa
    11461 tacatccata tttggtgctt tcgtcttgat tgcatggtac gcacctttat aaaaacgagc
    11521 accgacataa aattggacag gagcagacag cactaactgg acgattggaa aatgaaaaaa
    11581 gtgaacaatc gccgcatggc ttcctaacat catagcaatc attgacaaca tcaacggcaa
    11641 agtcaaaacc gtactcaata taagatcgaa tagcattttt ttcaaatacg cttgcttttc
    11701 ttctgcaatt ttttgtttgt gggcttcatc gtacaaaatt gcaccataac cgatgttttc
    11761 tacgctttgg attaattttt cagtggtcgt cccttcatat ttgacacttg ctttttcagt
    11821 ggccaagttg actgtggcat tgaccacacc aggttgtccg ttcagctctt tttcgatcct
    11881 agcagaacaa tttgcacaag tcatacctgt aatgacgaac gtatccattt tggtttctgc
    11941 tgttgccatc aaatcacctc tgctttataa cccaatccat tgattgcttg acaaatcttt
    12001 tcggattgaa cttttgtttc atcaaacttg accgtaccgt ttgctttttt caaatttact
    12061 ttcacttttt gcacgccgtc aagtgcgctt actgtttctt ctactcttgc tgcacaatga
    12121 ttgcagctca taccttcgat tgaaaattgt tgtttcattt tttcttcctc ctattgatgt
    12181 tgtttacatt cacattgacc tgggatacag ttacattcga tcgtatctac tggttgcttt
    12241 tgttccagtt gtttcaaaat ctcattgata tcttcttgag tcaaagtggc ttcttctact
    12301 agatccgcaa tcgtctctcc aatccttttt gcacagatat gggaaaaaag attttccgtc
    12361 gcactgcgaa ctgtttccat ctccgagaca gctggatgat aaatgaattt ttttccttct
    12421 tgttctgtcc agatcacttc tttttttacc aaacgtccca gcaaagtttt gatcgttgct
    12481 ggtttccaat ccatcgaatc agctaagatc tgcgtgattt cttgggctgt cgtctgtcca
    12541 agtgtccaaa taacacgcat gatctcccac tctgaatcac tgatctttac tggcgttttg
    12601 actttttcca tttatttcac acctttcgtt tacaaatgta atcattagct tatgaataca
    12661 gattacgctt gtaaacaaaa actgtcaatt atttttgctc tctattttca atttagttaa
    12721 aaattcttgt ttctctcgtc ttgttttaag gatgatcagt ttatttcttg cattagctac
    12781 ttggatcagc tgctgtattt tcggttcatt gttttcttca aaatgccaga taaaagataa
    12841 aaattctaag tattccctgt ttagtttctc tgaaaatgat tcaggcatat ctggccgaga
    12901 ttttttgttt atctttcttt ttagagaacg ccaaactact cggtagatgg cgagataacg
    12961 cggcacttta agccaaatga tcttatctgc ttctttaatc ctttcctcta atgtagaagt
    13021 ataatttcct tcaacaatcc atgacggatt agataccata aacgattgct gttcttgcaa
    13081 aaaccacttt tttgcctgaa tactgtagtc tgttgtatgc cataaaaggt ctagcggcag
    13141 tagcggaaag tcggtgattt ctttgatctt ccttgcgagg gtcgattttc ccgacccact
    13201 ttgtccaatc acgatgatct tcattcttct ccctcacttc tctttggaat ttggttcgat
    13261 cataccactt ataacgccgc aaaaaaacaa gggactgtga caaaagtcgt gtcaaagtcc
    13321 cttgtttcga ataaatggtg ttcaatcagc tgaccttcag cattaactca aaaaacggca
    13381 aaatatgagg agctattttt tcgtttgttc ctctaatact caggtcaaat cgctgatttt
    13441 acaacctctt ccttaaacgg tgttctcctg ccaacacctc ggtcacaagg cacaatagtc
    13501 aacaaacatg agaagttgtt ttttgaaatt gctccttgtg actcggagtt aaacggcagg
    13561 ctcactacct ctttcttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccagca
    13621 aaacgaaaaa tatgaggggc tatttttgtt tggctgttct tattacttga tgcaggacag
    13681 ctttttcaca acctctgatt cacggtgttc cagaagtagc ttctgcgaaa aacaagccga
    13741 aacttcacaa aaatttgaga agcaattttc gtaaattcct tcttatttct tgaagctgac
    13801 cacttctgtc acaacctctt gtaacaagta tttctatttt aaggctgaac cactgtttct
    13861 ggttcagtga tttctttgtt tttgtctcga cgagcaattg ctggcaagat catacctaat
    13921 aagatcaaga caattggtgt gatgatattc gtgaataatt ggaaccacca tgctttagga
    13981 tcagcagtat aatctacttt tggcaccatt cctaggatac atgcaaacgc agtgaaggca
    14041 aagcaccaag caccaaagat aaaaccgatt tttggatttt taacaaattt atattcagaa
    14101 ttgaatttct tataagcttt attcaacatc atatatgcca agaacaccca taggtaacgc
    14161 attggcatga caactgagtt caagttcgtc aaccatttta ctaattcatt catatctttg
    14221 ataccaaaga tcggcaacaa aataatgatt cctactagta tacctgtcag aagataacca
    14281 ttcaccaatg tacctttacg attacgttta cgtagccagt ttggtacaaa ttctggatcc
    14341 gcatctgcta acaagatttt tagtggtgca tcaattgaaa aggctaatgc ggagatttgt
    14401 ccaatcatgt ttgtcaatgc gtaaatgatc atcaatgagt taccgatacc atagtaatta
    14461 cctaaaattt gaaaagcact gtatgcccca tttgccatca agtctttagg aatattatcg
    14521 ctagcaaaca gcatacccat tgcgactgag cctaatacag cacaaatccc taccattgct
    14581 gctaagaaga tcatcccttt aggaaattcc tttgcaggat ttcttgtaga gttgacataa
    14641 ggggatattt tttccgctcc tccaactgca aatactagca tcgaaacggt tgtgaaataa
    14701 ctgaaatcaa atgttggaat atatgttttc acttgattca tatgtggtgt ggcaaattcc
    14761 atcgttggat tgatgaacgg tgccgttaca gctaaaagaa taaataagat cgacatgacg
    14821 aacatcgctg ttccggccag tccgccaatc actttcaaag tagaaagtcc ttttgttgat
    14881 aaatataaaa aggcaagaaa tataataagt gaaataactg ctaccatttg tactgacatc
    14941 gtatttacga tatttccatt tccttggact gcccaaccgc cagcaatcag gattgcttga
    15001 ggcttttgtg ccaaataagg aatatggacg acccagtaag tccaagcggc atagtatgcc
    15061 agtcgtttat tagatgtcgt attttcgacc catgaactga cgcctccttt actatccttg
    15121 aaggctgacc ctaattgtcc aacgatcaat gcgtatggaa taaaataaat ggccaaaatc
    15181 aatagccaag aggtgacaac tgatactcct tgctgagcat agttattaac tacattcccc
    15241 atgccccaaa ccatgttaaa tgcaattaac gcaacagtaa accagcgtaa ttgtttgttg
    15301 ttcattcgtt ctctccttta tgataaaaat ttgttatcca gatgtaatca tattcaattt
    15361 ttaacaaact tacaagacag tgttatttta tgtgtgtatt cttttattta atacacatcg
    15421 ttttttcata ttttttccat caaaaaaata agttattttc ttttatttca tttaccttat
    15481 tgaatttcaa gctattttga attttctgca aaattaaaaa cattagttat tttataatcc
    15541 tatctatttt ctttacattt ttcattaaga aaaggatata aaaaaaagag gacgttcatt
    15601 cgtcctcttc attgatcaac gtttattttt tacatgcaag cttcgcatgg cattcaaaac
    15661 agctaatact gtcaccccaa catctgcaaa tactgcatct cccattgatg caaaaccaaa
    15721 agcacctaag gcaagtacca aaatttttat cccaatagca aagacaatgt tctgtttgac
    15781 gattttcaat gttttctttg ctaaatggat tgcttctgca atcttcgatg gttgatcatt
    15841 catgatgact acatctgctg cttcaattgc agcatcgctt cccaatccac ccattgcgat
    15901 tcctacatct gctcttgcta gcaccggtgc atcgttgatt ccatctccga caaatgcggt
    15961 ctttttattg tttctttgta agatttcctc taaccgctgc actttatctt ctggaagcaa
    16021 ttcgctatat atcttgtcca cgcctacttg cttcccgata tgatcagcaa tttttttcga
    16081 atcgcccgtc aacatgactg tgttcttcac accagccttt tttaattgaa ccaatgcgtc
    16141 tacggcatct tctttcaagg tatctgcaat aacaagataa ccactgtaac tttgatcgat
    16201 cgctagataa agcaatgtac cgatttcttg acttgaagga aaagagattt caaatctttc
    16261 catcaatttg tgattacctg ctaatacttg tttgccatca acttcagcta agatcccttc
    16321 acctgcaaat tcttggatat tagctgttgg taaaagcgga cctgcgtagc cttctaaaac
    16381 agattgagca atcggatgtg tagaaaactg ttctgcactc gcaacatatt gcatgaatat
    16441 ctttggatcg atttttgtat cgatcgtctg gatcgaaaag tcacctttcg ttaatgtgcc
    16501 ggttttatcg aataccactg tctcagtttg tgcaagcaac tccaagtaat ttgaaccttt
    16561 tactaataca ccgattttac ttgctcctcc gataccgcca aagaaactaa ggggtacgga
    16621 gatcactaat gcacatggac atgagatcac taaaaatgtc aatgctcgat agatccattc
    16681 agaaaacgcc gctccagaaa caacaagtgg aggtaaaaca gctaataaaa cggccaatcc
    16741 tacaacgact ggtgtgtaat agcgcgcgaa tttagtaatg aaattttcag ctggtgcttt
    16801 tttactgctg gcattttcta ctaattctaa taatttgctg atagtagaat tttcataaga
    16861 tttttctact tgaactaaaa atggtttatt tttattgata aatccactta atactgtttc
    16921 accaacatat acagatttag ggactgattc tcctgtaagt gctgacgtat cgactaatga
    16981 ttctccttcg atgatcgttc catctaacgg tacacgttca ccaggcttca caagtacaaa
    17041 ctgaccgatc tgcacgtctt cagggttcac ggtcatcaat ccttccgtcg tctgcacgtg
    17101 agctgtttct ggacggatcg ccatcaattc gcgaatcgat tttcttgaat gactgactgc
    17161 caatccttgg aaatactcgc cgatttgata aaatagcatc actgctacgg cttctggata
    17221 ttcaccgatc aacatagcgc caatcgtagc aacagacata agaaaattct catcaaagat
    17281 ttttcctttg acgatattca tcactgcctt cttcactaca tcatatccta tcagcagata
    17341 aatcaataaa taccctatca agcgaattgg ttcattaaaa tcaaataata gcaataaagc
    17401 gatacctgca agggaaaata aaatccggaa cagcgtattt ctctcttttt catttccatg
    17461 ttcagatact ttttccttat ctatttctgt tactttgaca tctggttcta attccttcac
    17521 tacttttttt atttcttgtt caatcgtagc caaatgatct tcctctgcgt caatcgttag
    17581 ttttccagaa gtgaagttta ccgttgcttc cttgactcca ttgatcttct gaactccttt
    17641 ttcgattttc attgcacagt tcgcacaatc taaaccttct aatctgtaac ttttcatttt
    17701 aatgacctcc tcgcctcaac atatgaatat ctcttcataa ctaattataa atgaacggtt
    17761 attcatatgt caaggtatcc gaaagaaaaa atgaaaaaca tctgcatcgg aaaatttctt
    17821 ccatacagat gttttggctt attctttctt tttcttttcg atcattgcca ctgctcttat
    17881 ccaacccgca cttgccttct tgatcttgac aggatagcaa ctaagtttga agcctgttgc
    17941 tggcaatttg tctaaattca ttaatttttc gataggacaa tatctttttt caatccctgc
    18001 aaaatgtcct tcccagatat tcgaagctcc actacgcttt caaaaatata gaaagagttc
    18061 tttaatgaaa attatttcaa ctttccataa acagtaaccc catataaata aaagacgtaa
    18121 aagtcacatg gaagaactta tacaggagaa cgcatagagt caggtgaaat acatgtatcc
    18181 cacctgactc tatgctttat ctaaccttta ttattctctt ttatacaatt tctgcaccga
    18241 atggcatcaa cgccaatcga gcaagtttga aagattgctt ggcaaaaggt atccctatga
    18301 tcgtgataca tagaaggatg ccgctgacga catgtgcgag agcaattggt aggcctgaaa
    18361 cgatcagcca gatgatatta acaatcaatg acatgccaga ctggtgataa attacttctt
    18421 tgccaaaagg cgcaaaagaa agggaggcga tcttaaaaca ttgcataccg attgggatac
    18481 ctatgatcgt gatacaccaa agtatccccg ctgctaacca gctaagacca ccgattagtc
    18541 cgccgaatat aaaccagatg acatttccta aacaactcat tgtatttctc cttctattac
    18601 tgtttttgat taaaactggg caaaaaatga ttttattctt ctttttttag cttccagtat
    18661 caaatattct gcaaattttt tttggatttc ttccgtattt tcttttgtta ctaatgtgtg
    18721 ttggattagt tttcctgatg gtcgctgatc caatcgttct tctgactgtt gcacgtccgc
    18781 ttgcgcaaat ccgataatcc gtttttcttt tgttacagca acgagcaata gtttattctt
    18841 atcatttagg tcagctgccg tttttgcttt tacgaatgat tctggatgat cagtaatcag
    18901 ctgattgatt tgaggtagat cttcttttac tgcccaccgt atttccatca tttctcactt
    18961 ttctttcgct catttttatc tccactaaaa aaatcgactg cggcaattgc atctatccag
    19021 ctttgtgcaa tgatctcatg tccgccaatc gttgggtgga ccccatcttc tcttgtatat
    19081 ttcgaaaaac cataaacaat ccctaaagca ttgaatatac catctaaagg aaccagcaat
    19141 gcgccatatt ccttagcaag tttacgaaca atttggattt tagggtctaa gtctttacgc
    19201 cagccatgac ggtcgtcggt tataggaagt acaaacggct ccatcaagat gatgttgcag
    19261 attcccactg tttgaagttc atttagtaat tttcgataaa cggattcaaa ttgctgagca
    19321 gatttctcag ttccgaatat agcctgatcg ctagtattat gccaggtatc attgattccg
    19381 atcaaaatcg atacatagtc aggttgtaaa gctaaacaat cttcttgcca gcgtacttgc
    19441 agatctgcaa ttttgtctcc tcctatccca cggttcatgc attcaaattc catcgttgga
    19501 tattgggaga ttagttttcc ggcaatcaaa agtggataac ctttacctag atcagttgct
    19561 tctgctcggt ctcttcctgc gtctgtaatg ctatcaccga taaataatat acgttttttc
    19621 atttgtcaaa aactcctttt tgaataaaac gatgattttc ttccttatat tatcccataa
    19681 gccctatcaa gacgaaagag aaaatatatg tataaaaaat gacaccagcc tagtcccttc
    19741 aaacaattga atgaacgctc atcaagtgtc tagtttttta tgctattttt ttcttaacgt
    19801 gccggattcc ccttgattcc ttcgttgttt ggtccagaga gatcgatcac acctaagctt
    19861 ccgtcaatca gaccactgat gacgccatca gaacatatat ttataggctc atctaagact
    19921 tctagtaaat gtccctttac taatatctct tctagattgc ttgggataga ttggtcataa
    19981 ctttatctgg tccgatgatt tcaagggtga attgaactta catatggatt attgcatgct
    20041 gaaaatacgg acctactcca tcttcgaatg ttactattag tttgttttca ggtgctagat
    20101 gctgctttat ttcaacagca gaagcatcat caaatcagat ttccatttga attaccttct
    20161 ttgtaaatgt ttgattgatt gcgatttcgt tatagaacct tgtgaatcaa atagcaattt
    20221 cttttgcttt cttctcttgt ctgctggaaa cttcctttat cccgtatttt aaaaaaagaa
    20281 ctgcgagagt tcgcagttct tttttagaat aaacggtgct ctccggccaa ctcctcggtc
    20341 acaagtcaca atagtcatca aacatgaaaa actgtttttt gaaattactc cttgtgactc
    20401 ggagctgaac ggcaggcgca caacctcttc cttaaacggt gttcaaaagc cagtttctcg
    20461 gtattaagcc aaatttatgc aaaaatgtgg aaagccattt ccacaaaatt tttcttaata
    20521 ctcgaaacta aacagctttt tcacaacctc tccactaaac ggtattcaaa agcttacatc
    20581 tgcggtaata agtcccgcca attcaaaaac atgaacagct gtttttgctt ggctgttcta
    20641 attacttgat gcagaacagc tttttcatca cctcttatgg ataaattcgg ttcaacaaac
    20701 gtgggaatgg aatagcttca cgtacatggt cgataccagc aatccaagtg actgttcgtt
    20761 caagacctag accaaaacca gagtgcggaa cagaaccgta tttacgtaga tcaagatacc
    20821 atgaatattc tttttcatcc aaaccgtgat tacggatttg ttctagcaag aaatcatagt
    20881 ctgttgcccg ttcgcttccg ccaataattt caccgtaacc ttctggtgcg atcatatctg
    20941 cacagatcac cacgtcttct cttgttggat gtggtttcat gtagaatggc ttgatggctt
    21001 ttggatagtt taggataaag acaggctgtt cgaatgaatt cgcaatgaac gtttcatgag
    21061 gtgaaccaaa gtcttcgccc cattcgatgt catcaaatcc atttttcttc agtaattcga
    21121 tcgcatcatc ataagtaata cgagggaatg gcaattttgt ataagttttt aagacttctt
    21181 tgtctcgtcc tagtacatct aatgcatatt cgcaatgatc taaaacattt tgtactaaga
    21241 atgctacata ttgttcctgt acttctaaac tttcttcttg atgagtgaaa gccatttctg
    21301 gttcgatcat ccagaattcg atcaaatgac gtcgtgtttt tgatttttca gcacggaaag
    21361 tcggaccgaa tgaaaagact tttccgaaag ccatagcagc agcttccatg tataattggc
    21421 cactttgaga taaataagct ttttgatcaa agtaatttgt ttcgaataga tccgtagtgc
    21481 cttctggtgc agaaccagtc aagatcggcg gatcaatttt gacaaaatga tgttgattaa
    21541 agaattcata cgttgcacga atgatttcat ttctgatctg cataatcgca tgttgtcttg
    21601 aagaacgcag ccataaatga cgatgatcca tcaagaagtc tgttccgtgt tcttttggtg
    21661 tgatcggata atcgtggctc tcgcttacca cttccacatt tgtaattccg atttcataac
    21721 caaattttga acgactgtct tcacggattt ctccagttac taacacggat gtttcttggt
    21781 gtagattttt agctgtttgg aaaacttctt ccgacacttc gctttttaca actacacctt
    21841 ggaaaaaggc tgttccgtct cttaattgta aaaatgcgat ttttccgctt gatcgcttat
    21901 ttgcgaccca agcgccgatt gttactgttt ctcccacatg gtttttcgaa tcgatgattt
    21961 gaatttgttc cacgtatgac tctcctttta tattccttga atttctttag gattaatttt
    22021 gacttttact ctcaataaat tgcttgattc tgcgtaccgc ttcttctaac gtagcgcgat
    22081 cagtagcata actcatgcgg acattttctg gtgccccaaa gccttcgcca gtcacaagcg
    22141 ctacccctgt ttcttctaaa agatcttcta cccattgtgt gacattttca tatttacaca
    22201 tgcgtagcgt ttcttttaca ttaggaaaaa gataaaaagc tccttgtggc ttttcaagag
    22261 aaacacccgg cagttctgcc acaagcgaat ataacgtatt caggcgttct tcaaaggcgt
    22321 tccgcatttc ttccactgta tcttgctcgc ctttcaatgc ttcaacagct gcatattgac
    22381 tgactgctgt cggattactg gttgactggg aagcaacagc gatcattcca ttgatgatca
    22441 caggatttcc caccgcataa ccaatgcgcc agcctgtcat cgcatatgtt ttagacacgc
    22501 cgttgatgat gatagtctga tttttgattg cttctgaaat cgttgcaatt ggagtaaact
    22561 cattgccatt ataaactaaa cgaccataaa tatcatcagc aactatcaaa atatcatttt
    22621 ttactgccca ttcaccgatt gcctgcagtt cattcttgct ataaatcatt ccagtcggat
    22681 tcgatggaga attgatgatt acggcttttg ttttttctga acgtgcttgt tctagctgtt
    22741 caacagtaac tttccagcta ttggattctt cccctttcac aaagacagga agtccttctg
    22801 ccagttttac ttgctcaccg taactgaccc agtaaggcac aggaatgatg acttcatctt
    22861 gcgggtcaag gatcgtttgg aaaagggtat acaaagcaaa tttcgctccg tctgttacga
    22921 ctgtttgtga aggttcatag acaagtccat agtttttctt cagataatca acgattgcct
    22981 gtcgaagctc tgggattcct gctgttggtg tataatagct agctttcccg ttgcggattg
    23041 cttcgattgc tgcttcttgg atgttttctg gtgtcgcaaa atccggttct cccacagtca
    23101 aactcagcac atctctgcct tttgctttta atgccttggc ctttgccgca gctgccaaag
    23161 tgacagacgg ttctaatcgt tttgttcttt ttgataactc catcccattc attcctttac
    23221 cttttaaatt cccttgattg tcttgacttc atctccagat tcaaagccaa tcaggtaata
    23281 attcagtttc ccatttgttt cttttcctac tacttcccac acaggctgat catcatacat
    23341 ccctaaagca gctttttcga tttggatttc aggatgggcc gcagcaattg tctgttttgc
    23401 ttcgttttca gtcagtccct ttgtttgatc caatactttt actttttcac cagatttagg
    23461 aatgataacg gcgatttctt ttcctttatc atttgtacct gtcagtgaaa agtatgtctt
    23521 ctttcgagta aaccaataaa aatgatcggc ttcctcaaga tttgcatatt tctttgcgat
    23581 ttctactgct tctttcttcg cctgcaccgc cggacgactg gaacgcaagt aaaaaatcga
    23641 gctgatcacg atgaccgcta ataaaaatac gatcaagcca agtaacacgc gattaatcgt
    23701 tttttccttt gtctgttttt tcttcaaggg tcgtcgctcc tttatcttca ttccttttca
    23761 ttatagcaga ttttaattat gaaaaaagac agctcctcta acttccttct tcatttttct
    23821 ttaagaattc atggatgtcc tgatagattt cctccatagc tagctctttg atcggtactt
    23881 ttttcggtaa tgcatggatg atccgtgcac catattttgc agtgactagt cttcgatcca
    23941 aaataagcaa tacgccacga tctgtctccg tccttatcaa gcgacctaat gcttggcgta
    24001 acttcaaagc tgctttaggt acggattcct ggtaaaaagg attgatcccc tctgattcta
    24061 aataagcgtt cctagctttg accatcgggc gaagcggatt atcgaagggt aaacgtgtga
    24121 ctacaacgat ctgcaaagca tccccaggca aatctacacc ttcccaaaag ctgtcagcgc
    24181 caaacaatac gcttttttct gacaaaatga agcgtttcaa aagcttctcc cggcttccgc
    24241 caaacccttg agctagtatt tctcgtcctt tttctagcat agacagatgc attttctgat
    24301 agaccttctg caaaacatca tgagaagtga ataacacaag tattggccga tcttcttgtt
    24361 cgatcagacc tgtaagtgct gtctctaaat aatcgatata tgcttgattg ctgacttgat
    24421 ggacggcagg tgcctctttt ggcacataga tccttgcctg tttctcataa tcataaggag
    24481 aggcaatcac tttaagaggt gctgcttcaa tgccaagccg cttagagaga tagtgtcgat
    24541 tagggccgat cttcagcgtt cctccaatat aaagaatacg atcatatcga ggataccaaa
    24601 cagtcgacgg caacatagcc gcttgaaaat catggagatg aaaaatcatc tgctgcgctg
    24661 tgttcccagg aacgaaccaa tggatcaaat gatctcgcca gtcttccagc cattgatcca
    24721 tcagcaagta ctgcttgtct aattgatcaa ataagctata taaacttgct aaatcgatcc
    24781 gcatctggtt tgtccagctt tcttggataa tctcaaaagt cagacgcatt tgtgactgta
    24841 gctgctggat ctcctgataa aaaagctgca ggtgatcaat ggctgtccca gattccagtg
    24901 gcagctgatc caacatctct tttgtcatca tgacttcttc tggatactgt ccgttaggtt
    24961 gcttgccgct cactaaactc attaatcctt ctgccataca aatctgtgct tcgcatagcg
    25021 cagaaagttc ttctcgataa atcgataacc agcgtaaggc ttcatgttct ttcggtaaat
    25081 agctttgtat tcggtcaaac agctgatttg gttcttctaa ttgctggatt tgtttatgga
    25141 aatagttaat acttaatcgt ttgtcattta ctttttcagc gatttccggc aaatgatgta
    25201 cttcatcgat caacaaaaat ggactagctg gaagcaatgg ttcttttcgc tgtgtttctt
    25261 gtattaaaaa cgcatgattg acaatcaaaa aattactttg cctgattttc ttttgcaaga
    25321 aacgaacaaa gtcttgttcg taaaatgact gatttcttgc taaaaatcca atacctctgt
    25381 gcgcgatatc tgcaaagaat gaatggttca aatttgttaa atgtaattca tccaaatcac
    25441 cggtcttcgt ttgcgtcagc caaactaaga ccgccatttg atacaaagca tattgttttt
    25501 gttctggcgg ttccacaagt gtgcctttaa aacgctgtaa atcaatatag tggcgatagc
    25561 ttttgataat tacaggttgt atgggctgat ctagcaattg attcagcaat ggaatgtctt
    25621 tttctatgat ctgctgctgc aaaactagcg aaacggtact gatgacagcg ggtttttcag
    25681 gtgtagccaa ataactcaat ggcagcagat aaccgattgt tttacccatt cctgtagctg
    25741 cttcgatcat caaatctttt gattcatctt ttgtgaaatg gtcgtagacc gcattcatca
    25801 gtctgttctg ttcttttcga tacatcagtg ttttaccaaa cattttttct tttgcttgtt
    25861 tttttcttgg atatgtccgc tcgccataat ggacggatgt gaatagttcc acttcttttt
    25921 tctgcaaagc tagcccatcg acgatttcta atgagggatc aagtggctct ggtttttctt
    25981 tcatttcttc aatcacatga taaatgaaac gactcgtatc catacctgtg tgtctactta
    26041 atcgcgcaat ctgctctaac gtgatgattg gcaattttct catccgttct tcgatcagca
    26101 aaagaagttg acccgtcact tcggcatcac tatctgcctg atgaggattc tcatgaataa
    26161 atccaaggct ttctgacaaa tcagctaagc gaaagcttgg ttccgtcggc aagaaaattt
    26221 gtgcaagttc tactgtatcg atgcctggta tcttcaaact aggaagtccg catcgcatga
    26281 gttcatggtt caaaaaatta taatcaaaat aaatattatg cgcgacaaat atggtgtctg
    26341 ccaaaagatt gtaaatcgtt tgggcgacat cttcgaaata aggcgctttt tggacgcgtt
    26401 gattcgtgat ccctgttaaa tgctggattt gttttgaaat cttccgccct ggatgaatat
    26461 cgatcgaaaa acgtgaagtg atccgacctg attcaatcat gacgcagcca aattggatga
    26521 tccgatcttc ttttggattc gtcccagtcg tttcgatatc aacgactgca taagttcttg
    26581 gtttcaaaat atcttcctct tctcctgcct ctaatgttct tttgaaatta tactacaaag
    26641 tgcagaaaaa tactctcatc gctttttaaa gaaaatagac aaaaacgccc agacacgcaa
    26701 atgtctgggc gtttattttt tagtataggt taattaagct ttagtaacgt ttgttgcttg
    26761 aggtccgcgt tggccttctt caacatcgaa agttactgct tggccttctt ctaaagtttt
    26821 gaatccgtcg ccttggatag ctgagaaatg aacgaataca tcgtttccgt tttctgcagt
    26881 gatgaatcca aatccttttt ctgagttaaa ccattttact gtacctgttt ccataataaa
    26941 aatcctcctt gtgtatcaac acatattttg caattacttg aatggtgtat atctggaaga
    27001 tgtttatttg aaacaagcta ccacagatta ccgaacaaaa actactccta tagtatatca
    27061 taccgtttac aaaaaagcta gagtttttcg acttttttta ttaaaaaaag ttttctcagc
    27121 gattacataa agtgaaaaac cgaacttttt ttaaaataaa cgacatattg ttcagttggt
    27181 gtttttttgc tctgatgttc ttctttaaac taaaaaaatt attctttctg actacttatc
    27241 ggttctgttt caacggtcga ggctggggaa gattctttag taggtctgat gttctcatgg
    27301 tatttctgat agcctatgac agttaccaga agaacaaggc aaaccaatac gatcaacgag
    27361 attagttttt cttttttgct catatctata cctcataaat aacaggatga tgtccatcat
    27421 atttctgagt atgagtaaaa gcaaaagctg cagctgtaga atgtaagaaa tgccagcaac
    27481 tttcataatc acaggtcgga cagtaccaaa agtaaccaaa tcttggctgc aaagaccgtt
    27541 cttctgtttc aggaatcgca gaatcaagat ctgttgtctg tacataaaca tttttgtaca
    27601 gacgtgtgcc tgtaatagga gaccgctgtg tttcttcagc aaaaactggc tgacttgtta
    27661 aacttaggga tagaaacagc aaacaccata acagtctttt tttcataaag acctccttat
    27721 cgataagttt ttcccaatta aaatcatatc tcaagaacgc ccgttattca cattttgttc
    27781 ataaatgatg ttttttgtat cataatcgtc aaaaagaggt cgtgaccacg tcacaacctc
    27841 tttttt
//
LOCUS       DADVXM010000029        27782 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.030, whole genome shotgun sequence.
ACCESSION   DADVXM010000029 DADVXM010000000
VERSION     DADVXM010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.030"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            367..930
                     /locus_tag="KB927_001338"
     CDS             367..930
                     /locus_tag="KB927_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840265.1"
                     /translation="MTAIYKALKNSNVSEYVKSRVLNNNLDYILENGVADLISKLSDP
                     IDIDHLVVWQDGTLEVSIYGEFYSRNKVTTFKNSISGREDLKGINKNSKFYRTNKELL
                     EKISKRVFELVNPFSKTRSKELFGIFYDGFSAKSNVEKFFYFNDSAYIAVKDSKRIPE
                     ATLEYLEPIKLSVFYSLYEKEIADEAV"
     gene            917..1801
                     /locus_tag="KB927_001339"
     CDS             917..1801
                     /locus_tag="KB927_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraA"
                     /protein_id="HBB6840266.1"
                     /translation="MKRFKGSRMSKKIGKESLSLGLKKEIFKFKNMYSEPEFRLIFQL
                     DIVRGLKISFSCLGYLVWLFIARVGWSNAYSFYKLFAGTDRLKESLEVKEALNILGSL
                     AFSLFIFALFILQVGKIMMSTNDNYINYLKPFQKGIKIICRQGTVLFLLSLYEHEIHF
                     QNYYNTTTKLGAFLLLYLVSNIAEKMLFKHIVKQVFSDIKKESYCLKTPYGNLKNVEL
                     FLFKMDSKWDKYIYRSKEVFLTGSYNETLQESLYDTGAIFNNEPMVLKDFFGDYELVW
                     NPKQLSEQGAENEFAEVH"
     gene            2298..2552
                     /locus_tag="KB927_001340"
     CDS             2298..2552
                     /locus_tag="KB927_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840267.1"
                     /translation="MYNVGDQIDEIVKIGNVKLDKSKYCISETEIIFNTELGYILIWK
                     LPFPKDEETLKKINTLKIRYCVYEVIDKNTYVINQVKVMG"
     gene            2948..4549
                     /locus_tag="KB927_001341"
     CDS             2948..4549
                     /locus_tag="KB927_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBB6840268.1"
                     /translation="MLNSCEYADVLAKILKNGIKQFNSKNLVAFKKNSNKIGAIAGFT
                     SKTNMIKTKGLIYRSIDRVLEDSDVLTHWTPNVYSWLGGGENKTIFGHKEANLIQINT
                     FVADIDYPVGEKKTDLNLLVLYLLEEGLLPTLIVDTPKGYHCYFLIQNYNQETDSFDK
                     ASYISNSNDFKSLRVAKRISENIRKSIQNRLPQVDMGCNHFGIFRFPTKKNIVHYEPN
                     FVDTFEGYLKWSKDFEEKEYALKRSNLSLLAPNSTGKKGSKRQIDTKWYDFLIHTDIA
                     EGDRNKTVFTLALACKSSGLSIGECMDQLDQLQFNNDLSYSEVERTIRSAYRGDYKGA
                     KSSYVNEIIENYATPTEFEKYSINVNRQAVKRKGNRVDPSNWVKFAKPREERKYSHFE
                     ESKADLLAYLERKQRSLKKNELFLSVSMGTISEETQIPVSTLKVILKELRTANTVILQ
                     TSRGRYGSTKIATSKFVEAKILSTVIQNKKDKQVFVLELLGTANSHVETILRRYEDKT
                     VPFHANILKEREKSKHAPIRGANTG"
     gene            4783..5082
                     /locus_tag="KB927_001342"
     CDS             4783..5082
                     /locus_tag="KB927_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBB6840269.1"
                     /translation="MVIKKYVYSHPINVFIIGKLGLSVEVFCELYGFKQGTLSSWITR
                     EREVADLPISFLYALSLASGGNMNEVYDCLCEYEKEYKEYLKISAPKRNKKYIED"
     gene            5217..5576
                     /locus_tag="KB927_001343"
     CDS             5217..5576
                     /locus_tag="KB927_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HBB6840270.1"
                     /translation="MNIDGIYNESDFKKGDIAVIRSEYDFPSEIGIHTVEGKTVCRYW
                     GRKGNLILLLDTDSGDKLKFCFWHNTNYCCEPIPKRLIDVDKESVRYLADGTRIRLTY
                     QKSENASITRVRDIVVI"
     gene            5593..5811
                     /locus_tag="KB927_001344"
     CDS             5593..5811
                     /locus_tag="KB927_001344"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840271.1"
                     /translation="MELIPYAYQHLYKAKSMKDGNEVVGALICCPPFSYIATIESMKK
                     MCVDELNDGEVKNLKLTRVLERSIEEFR"
     gene            5826..8189
                     /locus_tag="KB927_001345"
     CDS             5826..8189
                     /locus_tag="KB927_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /protein_id="HBB6840272.1"
                     /translation="MATVILAEKPDQAEKFAFALADKKIPKSGGKFEFQSEVFGDTIV
                     TWGIGHLVGLSMPEKYEWLPNKEKWDLANLPFLPKMDELKYEVSKGKSQQFAVVKACL
                     ENADQIIIATDPDREGENIAYNIFKLCKQSIFKKPMKRLWINSLVKSEIIKGFKNLRN
                     AEETISFFEEANARQIADYLVGMNYTELYTLKLQQKGLSGVVSLGRVQTPVNTLVVEN
                     DLSIKNFKSEKYKVIECHTVDREPKVIFKNSREYFNLDEFEADTKKYGLDSASIGIVK
                     SVEKTLKQVEPQKLFSLGGIQEYANKKWKYSAKKTDKIIQSLYDRGYLSYPRTDSELI
                     TTNEFEYLKANLDVYKSVLGISIDTPCLEPKKRFVDNDKVLEHYALIPTMDIPDIANL
                     TLDEKNIYEIVTRRACLMFAEPYKYENTKVTLDVNGLEFTTSGNVPISLGWKQVDTNL
                     DESDDKEETLPKFHEQETINIDIRFIDKLTKEPKRLTEGKLLGKTGIMAKLGLGTPAT
                     RSNIVDTLLNREYIKIENTNVYPTPKGYLLWDLTKNKDLLIGKPENTAIWEESLGKIA
                     QGSYTQEAFLRNIYNYINKTVSDLKKVEFTSDYLEKTVNQNKFDIGSYQVEEKKKVYS
                     ILNITSGEQFVIFKNISGKAINKKVLQELLLNNRTDKVLSGFKSKEGKAFNARLLFDP
                     NVMKVVMEFEKNSPKGDKKSKHDTVNGYEIVEKAKVFEIKELATGESFIFYKNNSGKT
                     LSSKTVKELLENGKTKEKVTGFISKDNKKYSAYLVFDNKNKVIKKEF"
     gene            8507..9106
                     /locus_tag="KB927_001346"
     CDS             8507..9106
                     /locus_tag="KB927_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III toxin-antitoxin system ToxN/AbiQ family
                     toxin"
                     /protein_id="HBB6840273.1"
                     /translation="MNLKNTNSNKSTLYVISDDYINKLKKVDYRVQNNYREQRLYFKS
                     NLKISNKNEEINYYVPLASAKENQRSLTNKSVFKIYGDREEKDFLGVLHINNMIPVPK
                     DCAKVWTPNSPNVDEKYKMLVIKQAKYLKLHESEINESCELLYNSKLGKLDPSYFKKN
                     RKEVITYQKIMTNVESLEAVSIAESQRNIHVQTQSIDVE"
     gene            9218..9442
                     /locus_tag="KB927_001347"
     CDS             9218..9442
                     /locus_tag="KB927_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840274.1"
                     /translation="MISMARPRKYNTEEERKEAMKKARKKWVEKNQETIAYIRAKSFA
                     KKFIEMSEDEDIELLEKWLEDRKNNGQNDE"
     gene            9824..10030
                     /locus_tag="KB927_001348"
     CDS             9824..10030
                     /locus_tag="KB927_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840275.1"
                     /translation="MIENRVLGFVECKDNLDDTLEVLESIIFNTKVLDLKAINGDMTT
                     HIILDEISAKEIGETLIAWANKEL"
     gene            10110..10964
                     /locus_tag="KB927_001349"
     CDS             10110..10964
                     /locus_tag="KB927_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6840276.1"
                     /translation="MMKSNFLGYVIAINMFKGGVGKSTLTQLMADILSARGFKVLVID
                     VDPQGTVTKKFQRQYDLKVVGKMTLFEAVINMSFLDCISPVKENLDIVLGSEQMSRFT
                     KVLRDMWRSTGFTDEGEEVFWNLFNYMIGNDNLRDQYDFILFDTIPTVSEFTDNVYVA
                     SDFLVIPTQTEQDSIDNLHSTVTNYQTAVKEVNGDLEILGIVPYLVDTKLKTGLELLS
                     ELQEEYGDLVYSHIVSERGVIKRWGREGLNKSIPHSKTAYSMYVDIVEETLVRLEKAT
                     GENILERV"
     gene            10977..11414
                     /locus_tag="KB927_001350"
     CDS             10977..11414
                     /locus_tag="KB927_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840277.1"
                     /translation="MMSKTKKVTSAGSNGSGNPFGIKSGSGGFNIGQQMLKGKAGIKS
                     TGDKRKSVRVPVELYDEVVKDLSYGAKYSLMTEILALFLKEFETHGNSIVTDFGKLKT
                     RPVKISEEAFKVLKVIKFETDQSNTNIIASALTWYLDKRKGKA"
     gene            11734..12177
                     /locus_tag="KB927_001351"
     CDS             11734..12177
                     /locus_tag="KB927_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6840278.1"
                     /translation="MQILEDIKIYWKRIIGYTLVLLVVNLFLSMIALVFVNQRKDNVT
                     ELVTFISFFISGIFAPFFEETLMRGIIQNQLELKTNLSTRSIYIIVAILFSLSHLNLY
                     FIPYFMTSLILSFVYDNSDKRLIVPVTIHCFYNLIVILLSVVFYT"
     gene            12322..12645
                     /locus_tag="KB927_001352"
     CDS             12322..12645
                     /locus_tag="KB927_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840279.1"
                     /translation="MARSRIAKIEQTKKDKKISKNKTKFFKAEDVKRIAWSVKTFDED
                     RYVKVSMNGLFVQLGNFSNFKTIDELYPEIRNIVDSKGLIVAKRKSRNSGLAYCKNKG
                     IMIPA"
     gene            13063..16692
                     /locus_tag="KB927_001353"
     CDS             13063..16692
                     /locus_tag="KB927_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840280.1"
                     /translation="MKKLKLISIALFSLITMSTARQSIVSAEGTSTKAVVEESGDKKV
                     AIDDKVKNEAEKATVVQGADGLMYVVVDENDPEKLLEAESPLKNQQENTGAVEVGVDE
                     KRQEKADKANEKVKNFDDIDYNDISSLQSALNDPKFPFLSEDELNEKLQKTKNTFESE
                     ALMKKTRGYFSQRILELSNNLNDVPKRAKVSRHALVSNRASQVSETRINPPNGYPWVI
                     YLIRSNGYSYTENYAIRRTIDGKEAFCLQAGVQATNTYTGSTSGYLSNSQREMISSIL
                     SAYKELGGWANNDAGKQRWIATQMLVWENSNEKPKSITVTPNWKNGATKWKNDLVARA
                     NAIRVRTKWDSTSKTVDEGDKATFKVTNTYGDHNLHVKSVSGGGKATISNGTLTVDTT
                     GATGNKITVDMIKGSHPSDAHPTTVWSNGSYQKLVTGSFYISTSVTVNVKRKGTVEVL
                     KVDSETKKPLSGATFRFSYSGKTKDVTTDSNGKAKLTERLKAGTVVKVKEIKAPNGYQ
                     LDSSEFSITVKENQNVTTTRTNKKSTGSVEIEKIGDLDGLGLPNVVFTIYNSDNKVVK
                     DNLKTDSNGKIKVDELQFGKYYAVEKQGVTGYDPDGKKYNFEISQDTPFTKPAKVKVT
                     NIYEVSISEKVSDMNESQVLKNNWSADPNDYLQYDITTGNLKKSGERNVQSFIIEGFY
                     DNKNVDVSKSEVYVGSTNVTNSFDINNDTNNGKVIAKAKTSVLTNNDFYNKSYNLRIT
                     MKIKKSTLENTEKQKNLTIVKNSKVTVGSKISKSASSNDVETVLYSRKVTINHIDEKD
                     KHLLKQDIDYKYDGETYEYKPRTDLFDKDGNNYKSDVIHKGKIDGKDIVLNTPYHIPV
                     LSVNVDRIQIDTARAVKNGYLPTKIELSKKEEYEKELEKIVFKVKITDIDNNKVVYDE
                     NFKYKEFNSHMSLDLPTEYLTKNKKINYSVDILLVDNPDKNKFETETKDLRTIGYTSS
                     EKVLTNKDMTNNQVNYSAVVRTVKERENNNPVKEFNESINYKFTDSTKTKTGYGISVD
                     LEPTYRNEIGKQIDMKVYSYPMNELIDSKIDEIYQSGGKETEVKMDRLKNDGKVESGI
                     STQNLSFQFPHMNIERKTGNIYADSQRNDESIKYELIDGGRKLYVPIWCDLGNYSIAI
                     KSSNFGGNYISLDMNQNIDVYAYMYATIDSETKKDDELLLEPVYPESTLPDGWSKNEI
                     DWLNK"
     gene            16752..17114
                     /locus_tag="KB927_001354"
     CDS             16752..17114
                     /locus_tag="KB927_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840281.1"
                     /translation="MRVQSYGNSVFDVKREFQDSRRKTKKLIAYFILSAIVFYIVKFV
                     LELNSIVFTDMVHKMLNGEPINFNFDYMLEKAQSNQIVAFIVSIYYFIEKSIFSLKDF
                     FFEMLTKLTTFYNKISKN"
     gene            17128..17280
                     /locus_tag="KB927_001355"
     CDS             17128..17280
                     /locus_tag="KB927_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840282.1"
                     /translation="MLDQNTDRSWWMIGAVIVGAILIGTAKVAFPEVFNIVITFFKNM
                     IPTNLG"
     gene            17348..17770
                     /locus_tag="KB927_001356"
     CDS             17348..17770
                     /locus_tag="KB927_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840283.1"
                     /translation="MIYVAFFLDGSDVMLRDMPKMILLMFVGFFLILVIAYYSLNGYT
                     QDSSVKGMQETLRTTAIANRDDSIRVEKGRFALIKSDFEKDFKEKFGKSKNLNNETAD
                     YKFDYLTDGKDGIKAIKVKVESGSKEYQATCILNVAND"
     gene            17782..19197
                     /gene="tadA"
                     /locus_tag="KB927_001357"
     CDS             17782..19197
                     /gene="tadA"
                     /locus_tag="KB927_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBB6840284.1"
                     /translation="MRVVEEKKISPKIEETPKSKINIASIIKKNGIKENSEAIEGNLD
                     FLTKLLEEDSGNYEPPIEDAKLNMIRDDLTRNYSQEVLQALTDDEIRRKLVQVVLKEH
                     GTFFKKDKEVAEYVVRECIGTGIIERIMTNDEITDVGWNGSQLSIETNSNKWLFDGDK
                     LNITQEYIERVISKYAVVNDRAFNSGNPIMDGMFKNVRISATHIDNSPDGSTFSMRVA
                     RPRLALNKENFEDFAPDYILELFEKMMKTKANICISGETGTGKTELQKLLLSFIDNHD
                     RMIMIEDVQETHAKELFPDKDIFSWITTPKKAISDLVKASLRNNPRWIIVSETRGSEA
                     YEMLQAVLSGHYVVTTLHAVNARAIPRRFVNMCASGFKINENAVEEDINRYFDFGVHI
                     KKTVVDGKVIRYLNEIVEFSASEPTTVFKQKFINGKFVIENGSLSEDFKEKMAEKFIT
                     FEFPEDQTNTEESLPEEEEVI"
     gene            19214..20029
                     /locus_tag="KB927_001358"
     CDS             19214..20029
                     /locus_tag="KB927_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840285.1"
                     /translation="MTKRKGLMDVSELNAYQVAYGKPLDYRDYLNYVGLPCLFMGGFS
                     FALCYYWWIALICGVIGGVYGFKVIMPKSIKRSYELKSLQERNKFINNMTQILTDDSK
                     TVTRALSIAKQRTKGELREDIQILESRLQGADKFQIAEAFREINNKYYSDVVFTQYFE
                     QLETAIYEGRNNSDTMKQIKSYHNDVKRKTEGFMKIKDGYLQDMKQMMFIVAVFIGAI
                     TFAFGFSTFYEGFARSPIGWVFGSIYFLIMVSFMKSFFKHYFDDEIMSLGVSN"
     gene            20029..20826
                     /locus_tag="KB927_001359"
     CDS             20029..20826
                     /locus_tag="KB927_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840286.1"
                     /translation="MKVKALKKKRKSSISPLKITKTEHKSFWIKLLGDVYYQKLREMN
                     NSNIAIIKWQKQRLKKSLIFILVGFLMYLFLGKEWYYLAGGIATSVGFYVWQAKSING
                     IYNQFRFERHLQFSKFTRLLIPYLKQKKDGGNLYGVFAKIVKRLDYDTDKKLLMKLMQ
                     EMTDQPNDIRPFTEYAEQTSGTDMSVLFMSTVYDIRQGSADLDVIEELDRLASEELMA
                     GIDSIIDYKSRRFVFFPTKIAMTSFILVVGFAVGVLFMNLKDINFGQ"
     gene            20844..21206
                     /locus_tag="KB927_001360"
     CDS             20844..21206
                     /locus_tag="KB927_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4320 family protein"
                     /protein_id="HBB6840287.1"
                     /translation="MQEQSVMEIIKWFIGLMMIMAMVSIGLFCVQLQDINTFKQQVNY
                     QIERKGGLTTEAVEAIDKYSATNYDRRFTIESDKLNQKVSYGEEIDYTIKATIPIQIL
                     PLPDVTLSFNGNSVSQIR"
     gene            21378..21599
                     /locus_tag="KB927_001361"
     CDS             21378..21599
                     /locus_tag="KB927_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840288.1"
                     /translation="MEAIQENRKDNQETSEKNKKKRKKKVDKFTEMTDKIIEKKGLKP
                     KDFDRQAIKEARQKLYDDFVKENISQLLD"
     gene            21618..21893
                     /locus_tag="KB927_001362"
     CDS             21618..21893
                     /locus_tag="KB927_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HBB6840289.1"
                     /translation="MKNLVISKFAMLPRMDFFDNVSKFMSNMTSKLQGISLSVIIFCI
                     VVTGLMFLFGEGPSRTAKKWLTYIVIGAIIIFGASTIGQTIKSVGGF"
     gene            22002..23828
                     /locus_tag="KB927_001363"
     CDS             22002..23828
                     /locus_tag="KB927_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840290.1"
                     /translation="MNQRFEYNFEDVEPKLLKKGKGLKKKNKYTLKQAEALVGWIQHN
                     WSDKTTITLICSDTEEGTKYAFDGIEITPFSIGGQEKLLFPDIEGQILQAPDSMISDP
                     NKLILDINDQYKHEPDVAEPTKESKSKLNLKLPSVVLPFAKKKNKLMNELIEPEETDI
                     YEEELEEQEEIEELVVSSEETEEVEEIETVSENEEETEEIFDFEDEEEVENVQKGDLS
                     TSSQNGLEAVNDPQVPPYISSQTPNYSPQYQAPNVLQPLRKHETVQLVTLKEYCDLGE
                     EIETSISQMVEKLKPESLFKFIGIPSTGLTNTRIDEYRSNHAMLRLAEVKFENLREHY
                     SRQIISFKAEALDRLRTAVDIAWKKPYDLDVKKNKAEELSKMEAEAEAKLNEFVKRQE
                     NNVNDKIKKFEIEQEIDLKNFIARQEADKAVFIATEKDRTQNLIDSKAESINADLLET
                     KDKFIDEEMYKMKIEMNKNLFDGKQKIKSELATELAKANDNVWENALKFIQEIQDEIE
                     AKTPIWAAEIKEFNSLEEQEHERMKQTKELQLKEESIEIKRLEAEMNLKRMEELDHEN
                     KMLKIKLETALSKNELLAMEQDTKQVVNGSNRVGALNLFSKR"
     gene            23841..24557
                     /locus_tag="KB927_001364"
     CDS             23841..24557
                     /locus_tag="KB927_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840291.1"
                     /translation="MSVFNNKVMLGNCYVNHIGFYDGGTYRVLFLRLSVFSYSKDGKG
                     HYENINAQISCPLDRNGETTTTSSHPKALMNKFIFEKLDRNLVEGMKISIHGNIRGTE
                     QVLLNSGWKNFGQLSPLEKEEYQKIPKNELVTRNQTYIYIEEVSMPEKEEFRKSQSKV
                     TKEDVEVAEPNQADEILSDDTDPVNDEGEVIEVFEAEIIEEEEEIKSFDKRMYREKPK
                     GYVNFEDMYYDEYSNEPPIN"
     gene            24570..26629
                     /locus_tag="KB927_001365"
                     /pseudo
     CDS             24570..26629
                     /locus_tag="KB927_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311855.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            complement(26593..27771)
                     /locus_tag="KB927_001366"
     CDS             complement(26593..27771)
                     /locus_tag="KB927_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HBB6840292.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRG
                     VQEVLLFITDGLKGMKDTIHQIYPKAKYQHCCIHVSRNIAHKVRVKDRKEICDDFKAV
                     YQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDLLTFYDFPPSIRRTIYSTNLIE
                     SFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLVSMFTE
                     "
BASE COUNT        10442 a         3427 c         5267 g         8646 t
ORIGIN      
        1 atgatttact aattcataag aatgaaaata gtaatattgg tagaattata atcacaaact
       61 taatagtaat tactattggg attacaacat taacaaataa agctttaata tcaagtatga
      121 ttttaatagt gtttgatttt attatcattt atagtttgct gtttttaata aagaaagtaa
      181 ctgaatattt aaatcgttag gcatgaaata aattttaatt gaggttgaat tatagcggta
      241 aatcatacaa aatagaaatg tagtcttgtt aagcgtcttg actatctaat tttgaatgag
      301 gagggttgta tatagaaaaa gggtagttaa attcgtagat caaaaggcta cgaaggagaa
      361 tatagaatga cagctattta taaagcacta aaaaattcta acgtatcaga gtacgttaag
      421 tcgagagtat taaataataa tttagattac attttagaaa atggtgttgc tgatttaatc
      481 agtaaattaa gtgatcctat agatatagat catttggtgg tatggcaaga tggtacttta
      541 gaagtatcaa tatatggaga attttatagt agaaataaag taactacatt caaaaatagt
      601 attagtggtc gagaagattt aaaaggaatc aataaaaata gtaaattcta tagaacaaat
      661 aaagaattgc tagaaaaaat ttcaaagcgt gtttttgaat tggtgaatcc attttcaaaa
      721 acacgtagta aagaactttt tggaattttt tatgatggtt ttagtgcaaa aagtaatgta
      781 gaaaaatttt tttattttaa tgattcagct tatattgcgg ttaaagacag taaaagaatc
      841 cctgaagcaa ctttagaata tttagagcca attaaattgt ctgtttttta ttcactttat
      901 gagaaagaaa tcgctgatga agcggtttaa ggggagtagg atgagtaaaa aaataggcaa
      961 agagtcgtta tcgctcggat tgaaaaaaga aatttttaaa tttaaaaata tgtatagtga
     1021 gccggaattt agactcattt ttcaattaga tatagtgaga gggctgaaaa ttagttttag
     1081 ttgtttaggt tatctggttt ggctattcat tgctagagta ggatggagca atgcttatag
     1141 cttttataaa ctgttcgccg gaactgatcg attaaaagaa tcattagagg tgaaagaagc
     1201 cttaaatatt ttaggaagtc ttgctttcag cctgtttatt tttgctttat ttatcttaca
     1261 agtaggaaaa ataatgatgt caacaaatga caattatatt aattatttga agccttttca
     1321 aaaaggaata aaaatcattt gtagacaggg cacagtttta tttctactta gcctgtatga
     1381 gcatgaaatt cattttcaaa attattataa tacgacaact aaacttggtg catttttact
     1441 cctatattta gttagtaata tagctgaaaa aatgctgttt aaacatattg taaagcaagt
     1501 cttttctgat attaaaaagg aaagctattg tttaaaaaca ccttatggaa atttaaaaaa
     1561 tgttgagctg tttttattta aaatggatag taagtgggat aaatatatct atagaagtaa
     1621 agaagtattt ttaactggta gttataacga aactcttcag gagagcctgt acgacacagg
     1681 agcaatattt aataatgaac ctatggtttt gaaagatttc tttggagatt atgaactagt
     1741 ttggaatcca aaacagctta gtgaacaggg ggcagaaaat gaatttgctg aagttcacta
     1801 acatagtgta cagaaaaaca ttatctgaaa gaagaacgcc ttcaaaagaa agtataagaa
     1861 cgattgggcc gtacagaaga ctaacgaaag atcgtaaaaa aaaggaaaga caatgaaaat
     1921 gtctttcctt tttttgacta caagtagcct gaaaatgaaa ttccaaaaga ctacttgtag
     1981 tcttttgtgg caaaaataaa gagccaacga aagctaccaa caatcgttga ctcgtaagac
     2041 tgttcgtagt aagaaaaatc tttggcaatc cacgaagtct ttatttcata atttatataa
     2101 atgattatac agtcattttc ctgaatttgc aagtaaaaaa gctaagaaat attgtttaaa
     2161 cgtttcctta aaagaatctt taaataaatt tttttccaat tgaaaacatg actacaagta
     2221 gactatttct tttattctaa gttgactaca agtagtcaaa atgatataat atgtatatca
     2281 agaaaggaga aacaaaaatg tataacgtag gagatcaaat agatgagatc gtaaaaatag
     2341 gtaatgttaa acttgataaa agtaagtact gtatttcaga aaccgaaata atttttaata
     2401 ctgaattagg gtatatttta atttggaaat tgccttttcc aaaagacgaa gaaactctga
     2461 aaaaaataaa tactttaaaa atcagatatt gtgtttatga agttattgat aaaaatactt
     2521 atgttataaa tcaagtaaaa gtgatggggt aaaaatcttt aaaaaaactc ttgttaaaag
     2581 taattctatt agcttataat gttggtatta gttctgaagc caaaggaaca ctaaaaaatt
     2641 ctagtagaaa agttagttac agactctcta ctatgtatga atgtaacgaa aaaaatagcg
     2701 aaaaagataa ttaaataaga ctaccaatct tatttaatgg aacttctgta gtaagaaaag
     2761 cgatttggca atccacgaag tccaccaaga tgagctacca actcatttta attgttgcac
     2821 gtttaaagtt tagcatttaa gtgcttactc taaaggcata gtgtaatttt aggactcctt
     2881 attacggaat ctaaagttac cctatgtctt ttttgctatt caaaattgat agcaaggaga
     2941 aagtgcaatg ttgaatagtt gcgagtatgc ggacgtttta gctaaaattc ttaaaaatgg
     3001 aattaaacag tttaatagca aaaatctagt tgcttttaaa aagaatagca ataagattgg
     3061 tgctattgcc ggatttactt ctaaaacaaa catgataaag actaaaggtc ttatatatcg
     3121 ttctattgat cgtgtcttgg aagattcaga tgtattaaca cactggactc ctaacgtgta
     3181 ttcatggctt ggtggcggtg aaaacaaaac aatttttggt cacaaagaag ctaacttaat
     3241 tcagattaat acttttgtag cagatattga ctatccagta ggagaaaaga aaacggattt
     3301 gaatttacta gttctttatc tattggaaga agggttattg cctacattga ttgtagatac
     3361 gccaaaaggt tatcattgct attttctgat tcaaaactat aaccaagaaa ctgattcatt
     3421 tgataaggca agctatattt ctaattcaaa tgattttaaa tctttgagag ttgctaaaag
     3481 aatatcagaa aatatcagaa aatctatcca aaatcgttta ccacaagtcg atatgggctg
     3541 taatcatttt ggtattttta gatttccaac taaaaaaaat attgtacatt atgaacctaa
     3601 tttcgtagat acgtttgaag ggtatttgaa atggtcaaaa gactttgaag aaaaagaata
     3661 tgctttaaag aggtctaact tgtcattatt agctcctaat tctactggca agaaagggtc
     3721 taaacgacaa attgatacta aatggtacga ctttttaatt catacggata ttgctgaagg
     3781 agatagaaat aaaactgttt ttaccttagc cctggcatgt aaatcaagtg gcttatctat
     3841 tggcgagtgt atggatcaat tggatcaact tcaattcaat aatgatttgt cctattctga
     3901 agttgagaga acaataagaa gtgcttatcg tggcgattac aaaggtgcta aaagttcata
     3961 tgtcaatgaa attatcgaaa attatgctac acctaccgag tttgaaaaat actcaataaa
     4021 tgtaaataga caagctgtta aacgtaaagg gaatcgtgtc gatccgtcta attgggtgaa
     4081 atttgctaaa cctagagaag aacgaaaata tagtcatttt gaagaaagta aagctgattt
     4141 attagcttac ttagaaagaa aacaaagatc attgaaaaaa aatgagttgt ttttaagtgt
     4201 ctctatggga actatatctg aagaaacaca aattcctgta tctacgttaa aggtgatttt
     4261 aaaagagctt agaacggcga atacagtgat attacaaacg tctcgtggtc ggtatggatc
     4321 gactaaaata gcaacaagca aatttgtgga agctaaaata ttaagtacag ttattcagaa
     4381 taaaaaagat aaacaagtat ttgtcttaga attattagga acagcaaata gccacgtaga
     4441 aacgatttta agacgttatg aagacaaaac agtaccgttc catgcgaaca tactgaaaga
     4501 aagagaaaag agcaaacatg cgccaattag aggagctaat acaggttaga gttctattta
     4561 tttttttgat ttttaaatag ctaaattgcc aattaacata tctagtgttt ctgctcactc
     4621 ctattcctgt tttaacgtat actaatcatt agtagttagt actctctttt acgtatggag
     4681 tgcatagaac tatttttact tgtgtctttt cccttaatcc acgtgtacgg aatacagctt
     4741 ataactgcgt atgcagttat gtttgaagga ggaagatttt ctgtggtaat taagaaatat
     4801 gtttactcac acccgatcaa tgtatttatt atcggtaagc taggtttatc tgttgaggtg
     4861 ttttgtgagt tatatggatt taaacaagga actctatcgt cttggattac tagagagcgt
     4921 gaggtagctg atttgcctat ttcttttttg tatgctttgt ctctagcttc aggagggaat
     4981 atgaatgagg tttatgattg tttgtgtgag tatgaaaaag agtataaaga gtatttgaaa
     5041 atttcagccc caaaacggaa taaaaaatat attgaagatt agagaaagaa gaaaagaata
     5101 atttgctttt tgactacaag tagactgata gctactctgt tttttgatag tttgatattg
     5161 gctgtttttt tgttagaatt aatatatatc aggtaaataa aaaaaggggg ctattaatga
     5221 atattgatgg gatttataat gaatcagatt ttaagaaagg cgatatagcg gtaatacgtt
     5281 cagagtatga ttttccttca gaaataggaa tccatacagt agagggaaaa actgtttgtc
     5341 gttattgggg tagaaaaggg aatttaatat tattattaga tactgattca ggtgacaaat
     5401 taaagttttg tttttggcat aatactaatt attgctgtga acctattcca aaaagattga
     5461 ttgatgtaga taaggaaagt gtaagatatt tagctgatgg aactaggatt agattaacgt
     5521 atcagaagtc tgaaaatgct tcaattactc gtgtaagaga tattgttgta atctagtggg
     5581 aggtgaagga ttatggaatt aataccttat gcgtatcaac atttgtataa ggctaaatca
     5641 atgaaagatg gtaatgaagt tgttggagcg ttgatttgtt gtccaccatt ttcttatatt
     5701 gctaccattg aatctatgaa gaagatgtgt gttgatgaat tgaatgatgg tgaagttaaa
     5761 aatttaaaat taacacgtgt attagaacgt tcaattgaag aatttaggtg aaggagagag
     5821 tatttatggc aactgtaatt ttagcagaaa aaccagatca agcagagaaa ttcgcttttg
     5881 cgttagccga taagaaaatt ccaaaaagtg gaggaaagtt tgaatttcaa agtgaggtat
     5941 ttggagatac gattgtaact tgggggatag gacatttagt tggattatca atgccggaaa
     6001 aatatgaatg gctacctaac aaagaaaaat gggatttagc taatcttcct tttttaccaa
     6061 aaatggatga gttgaagtat gaagtttcaa agggaaagag tcagcaattt gccgtagtta
     6121 aggcgtgttt agaaaatgct gatcaaatta ttatagccac tgatccagat cgtgaaggag
     6181 agaatattgc ttataatatt tttaagttgt gtaagcaatc tatttttaag aagcctatga
     6241 agcggttgtg gattaattct ttggttaaaa gtgaaataat aaagggattt aaaaacctta
     6301 gaaatgcaga ggaaactatt tctttctttg aagaagcaaa tgcacgacaa attgcagatt
     6361 atttagtggg aatgaattat acagaattgt atacattaaa attgcaacaa aaaggcttat
     6421 ctggggtggt atcactaggt agggttcaga cacctgttaa tacattggtt gttgaaaatg
     6481 atttatcaat taaaaatttc aagtctgaaa agtataaagt gattgaatgt catactgttg
     6541 acagagagcc aaaagttata ttcaaaaata gtcgagaata cttcaattta gatgaatttg
     6601 aagcagacac taaaaaatac ggtttggatt ccgccagtat aggaattgta aaatcagtag
     6661 aaaaaacatt gaagcaagta gaaccacaaa aattatttag tttagggggg attcaagaat
     6721 acgctaataa aaaatggaaa tattctgcta aaaaaacaga taaaattatc caaagtctat
     6781 atgatcgtgg atatttatct tatccaagaa ccgatagtga attgataact acaaatgaat
     6841 ttgagtattt aaaagcgaat ttagacgtgt ataagagtgt tttagggatc agtattgata
     6901 caccttgttt agagcctaaa aagcggtttg tagataatga caaagtatta gagcattatg
     6961 cactaatacc aacaatggat attcctgata tagcaaatct gacattagat gaaaaaaata
     7021 tttatgagat cgttactagg cgtgcgtgtc taatgtttgc agaaccttac aagtacgaaa
     7081 atacaaaagt tacattagat gtaaacggct tagaatttac cacaagtggt aatgtaccta
     7141 tatctttagg ttggaagcaa gtagatacta atttagatga atctgatgat aaagaggaaa
     7201 cattacctaa atttcatgaa caagagacaa taaatataga tattagattt attgataaat
     7261 taactaagga acctaaaagg ttgactgaag gtaaattatt aggtaaaacc ggtattatgg
     7321 cgaaattagg gctaggaacg cccgctacac gttctaatat tgtagacact cttctaaata
     7381 gggaatatat taagatagaa aacacgaatg tttatcctac tccaaaggga tatttattat
     7441 gggatttgac aaagaataaa gacctattga ttggaaaacc agaaaataca gcgatatggg
     7501 aagaatcact tgggaaaatt gcgcaaggta gctatacaca ggaagctttt ttaagaaata
     7561 tctataacta tatcaataag actgtttcag atttgaaaaa agtagaattt acttcggatt
     7621 atttagaaaa gactgtaaat caaaataaat ttgatatagg tagttatcaa gtggaagaaa
     7681 agaaaaaagt ttattctatt ttaaatatta ctagtggtga acagttcgtg atatttaaaa
     7741 atatatcagg aaaagcaatc aataaaaaag ttcttcaaga actattacta aataatcgta
     7801 cagataaagt cctttccggc tttaagtcaa aagaaggaaa agcttttaat gcaagattac
     7861 ttttcgatcc aaatgtgatg aaagtggtaa tggagtttga aaagaacagt ccaaaaggcg
     7921 ataaaaagag caaacacgat acagtaaatg gttatgaaat agttgaaaaa gcaaaagtat
     7981 ttgaaataaa agaattagca acaggtgaaa gttttatttt ctataaaaat aatagtggga
     8041 aaactttaag ttcaaaaaca gtcaaagaat tgttagaaaa tgggaaaact aaagagaaag
     8101 taacgggttt tataagtaaa gacaataaaa aatatagtgc ttatcttgtc tttgataata
     8161 aaaacaaagt tataaagaaa gaattttaat tcttagtggc ggaaatcatt tgtttttccg
     8221 cttattttta ttcaaaagtg cccaaaatat aggtatactg aattaaggat aaatacaaaa
     8281 ctagttagag gacagttgaa aaaatacaaa caaattagat tgctattttg ttaaattgga
     8341 agtagaataa taccgttttg atatgtatag tgtgttttac caataaaatt acataaacgt
     8401 gaatatattt ttatgaatta aatgtaaaat gagagcaatt agttttaaaa aagattatag
     8461 gctgttaatc ttagcatata taatccattg gaaaggggga gatccaatga atctaaagaa
     8521 tacaaactca aacaaatcta cactatatgt aatttcagat gattatataa ataagctgaa
     8581 aaaggtggac tatcgtgtcc aaaacaacta tcgagaacaa cgattatatt ttaaatcaaa
     8641 cttgaaaatt tctaacaaaa atgaagaaat aaattattat gtaccattgg cttcagcaaa
     8701 agaaaatcaa cgttctttga ctaataaatc agtgtttaag atttatggtg atcgagaaga
     8761 aaaggacttt ttaggagtac ttcatataaa taatatgatt cctgtgccaa aagattgtgc
     8821 aaaagtatgg acacctaata gcccaaatgt tgatgagaag tataagatgt tagtaatcaa
     8881 acaggcaaaa tatttgaaat tacatgagtc tgaaataaat gaatcatgcg aattacttta
     8941 taattctaag ttaggtaaac ttgatcctag ttactttaag aaaaatcgta aagaagtaat
     9001 tacttatcaa aaaataatga cgaatgtaga atcattggaa gctgttagta tagcagaatc
     9061 ccaaagaaat attcatgtac aaactcaaag tatagatgta gagtaagata ggctaaacct
     9121 atcttatttt attattctat tggatattat gatacattga attttaatcg aatatgtatt
     9181 taaatgttat tatactgtag aagataaaac ttaaaggatg atttctatgg cgagaccgag
     9241 aaaatacaat acagaagaag aaagaaaaga agcaatgaaa aaggctagga aaaaatgggt
     9301 tgaaaaaaat caggaaacta ttgcctatat aagagccaaa tcatttgcta aaaaattcat
     9361 tgaaatgtct gaagatgaag atattgaatt gttggaaaaa tggttagaag atcggaaaaa
     9421 taacggtcaa aatgatgaat aataaccatt gactacaagt agtcaatggt gtagaatggt
     9481 tttagggata gaaatatccc ttttctaaaa gtctaatgac tacaagtagt cgatagaggg
     9541 atcgggaata aaaacagacg attatggcct aaagaaagga ggaatatgaa tattttgagg
     9601 aacgatttat taaatgagcg ttgataaatt tcactaaata ttttcttaat atctatgtat
     9661 tgttcaagcg tagaaaaaaa tattgaaatt attacaaaac cgctcataat ggaaaataac
     9721 gaattatatt aatgaatcgt tcacttttga ccttttttac tagatttttt tgtaggactt
     9781 ttagagaatt tttttgttat ctgattataa ggaggagcta aagttgatag agaatagagt
     9841 actggggttc gtagagtgta aagataattt agacgatact ttagaagtcc ttgaaagtat
     9901 tatatttaac accaaagttc tggatttgaa agcaattaat ggtgatatga caacacatat
     9961 catattagat gaaattagcg caaaagagat tggcgaaact ttaatagcat gggctaataa
    10021 agagctgtaa aagataattt taaaataaag tggccaattg actacaagta gtctgtatag
    10081 tataataaat tatcaaaagt gaggtataca tgatgaaatc aaattttttg ggatatgtaa
    10141 ttgcaatcaa catgtttaaa gggggagttg gtaagtcaac tcttactcag ctaatggctg
    10201 atattctatc ggctagaggc tttaaagttt tagttattga tgttgatcca caaggaacag
    10261 taactaaaaa gtttcaaaga caatatgatt taaaagttgt tgggaaaatg acattgtttg
    10321 aagcagtaat taatatgtct ttcttagact gcatttctcc tgttaaagaa aacttagata
    10381 ttgtgcttgg ttcagaacaa atgtcaaggt ttaccaaagt attaagagat atgtggagaa
    10441 gtactggttt tactgatgaa ggtgaagaag tcttttggaa tttgtttaat tatatgatcg
    10501 gtaatgataa tttaagagat caatatgatt ttattttgtt tgacactatt cctacagttt
    10561 cagaatttac agataacgtt tacgtggcga gtgatttttt agtaattccc acgcaaactg
    10621 agcaagattc tatagacaac ttgcatagta cggttactaa ttatcaaact gctgtaaaag
    10681 aagtaaacgg agatttagaa attttaggta ttgttccata tctagtggat actaaattaa
    10741 aaacaggatt agaactttta tcagaacttc aagaagaata tggagactta gtttattctc
    10801 atattgtttc agaacgaggc gtaattaaac gttggggtag agaaggacta aataaatcta
    10861 tcccacattc taaaactgct tatagcatgt atgtagacat tgtagaagaa acgttagtac
    10921 gtttagaaaa agctacagga gaaaatattt tagaacgtgt ttaggaaagg tgttgcatga
    10981 tgtcgaaaac taaaaaagta actagtgccg gcagtaatgg ttcgggtaat ccgttcggaa
    11041 taaaaagcgg tagtggtgga tttaatatag gacaacaaat gttaaaaggt aaagctggca
    11101 ttaagtctac tggtgataaa cggaaatctg ttagggtacc agttgaatta tacgatgaag
    11161 ttgttaaaga tttatcatac ggggctaaat attcattaat gacagaaatt ttagctttat
    11221 ttttaaaaga atttgaaaca catggaaata gtatagttac tgattttggc aagttgaaaa
    11281 cgagaccagt aaaaatttct gaagaagcct ttaaagtttt gaaagttata aaatttgaaa
    11341 cagatcaatc taatactaat attattgctt cagctttgac atggtatctt gataaaagaa
    11401 aaggaaaagc ataatgaaat gaggtaagac tatggatcat aaatcaaatt attcatacaa
    11461 agaaaattat atttggaagt atgtagtagc cgtttttcta ctggtaggtg gaattattgc
    11521 attggttaaa tgggctataa ttcctaatgc tttagtattt atcaattggt ttgtccctaa
    11581 tttttggagt ttttttggct atatattgat aatctggttt atgtttaaag tactctcttt
    11641 tttctggtcg cctgtatatt ctttgcttgg aaagtggtcg tacctaattt taatagcgac
    11701 agctatttat atcattatgc agattaacta attatgcaga ttttagaaga tattaaaatt
    11761 tattggaaaa ggataatagg ctatacatta gttcttcttg tagtaaattt attcctttcg
    11821 atgatagcgt tggtctttgt taatcaaaga aaagacaatg taactgaatt agtaacgttt
    11881 atttcgtttt tcataagtgg gatttttgct cctttctttg aagaaacctt aatgagagga
    11941 attatccaaa accaattgga attaaaaaca aatttgtcta caagaagcat atatataatt
    12001 gttgcaattt tgtttagtct atcccactta aatttatatt ttattcctta ttttatgacg
    12061 agtttaattt tgtcttttgt ctatgataat tcagataaaa ggctgattgt tccggttact
    12121 attcattgtt tttacaattt aattgtaata ctgttaagtg tagtttttta tacttgaaaa
    12181 aaatagacga aaacctaaaa atacaaggtt tttatctatt ttttttattt tgtttttatc
    12241 tatcaggttg atagaaattg tcataaatga tataattaag tatgaactga tttagtaaaa
    12301 aaattaaagg agtgatagct gttggcaaga tcaagaattg ctaaaattga acagactaaa
    12361 aaggataaaa aaatttctaa aaataaaaca aaattcttta aagctgaaga tgttaagagg
    12421 atagcatggt ctgtgaaaac atttgatgaa gatcgttatg ttaaagtttc aatgaatggt
    12481 ctatttgtac agcttggtaa cttcagtaat tttaaaacga ttgatgaact ttatccggaa
    12541 ataagaaata ttgtggatag taaaggttta atcgtggcta aacggaaatc aagaaactct
    12601 ggtcttgctt actgtaaaaa taaagggatc atgattccgg cttaaatcag tgaaattgtt
    12661 ctttgaaaac ttaatactac tcgtactgta gcaatgttgc tatgttacag ataaaagcgt
    12721 aaggctaata agcaaaatag caaccaagca tactgttatt tcctttgcca agaggtatgt
    12781 aaatacgtta gcaatagaag tgataaggtt agtatttcac gccaaaaaat acaaaagtcg
    12841 atccattgaa actactaatt atgaggtggc gtaaatggta attattcaga atttctatct
    12901 aggaagaacc tatgaaaacc gtcctagaga tcagaatatt gacactaaaa aattcagcac
    12961 agtaataaat gtgctagata cagggtaact ctttactaca agaaatgtag taaagagttg
    13021 ttatgattct ttattacatt tctttctaaa ggaagtgtga taatgaaaaa actaaaactg
    13081 attagcattg ctctattcag cctaatcact atgtcaacgg ctcgccaatc aattgtttcg
    13141 gctgaaggaa cgtctacgaa agcagtagta gaagagtctg gcgataaaaa agttgctata
    13201 gacgacaaag tgaaaaacga agcggaaaaa gcgactgtgg ttcaaggggc agacggcttg
    13261 atgtatgtgg tcgttgatga aaatgatcct gaaaaattgc tagaagctga atctcctttg
    13321 aaaaatcaac aagaaaatac cggcgctgtt gaagtcggtg ttgatgaaaa gagacaagaa
    13381 aaggctgata aagctaacga aaaagtgaaa aactttgacg atattgatta caacgatatt
    13441 agttcgttgc agtcagcgtt gaatgatccg aaattccctt ttttatcgga agatgaatta
    13501 aatgaaaaat tgcaaaagac aaagaataca tttgagtctg aagcgctaat gaaaaagaca
    13561 aggggatatt tcagtcaaag gattttagag ttaagcaata atttaaatga cgtaccgaaa
    13621 agagcgaaag tgagtcggca tgctttagtt agtaaccgtg cttcacaagt aagtgaaaca
    13681 cgaataaacc ctccaaatgg ttatccgtgg gtgatttatt taattaggag caatggttat
    13741 agttatacag aaaattatgc tattagaaga actattgatg ggaaagaagc tttttgttta
    13801 caggccggtg tacaagcgac gaatacatac actggttcaa caagtggtta tctttctaat
    13861 tcgcaaagag aaatgattag ttcgatttta tcagcatata aagaattagg cggttgggct
    13921 aataatgatg ccggaaaaca aagatggata gcaactcaaa tgcttgtttg ggaaaacagt
    13981 aatgaaaagc ctaaaagtat aactgttacg ccaaattgga aaaacggagc tactaagtgg
    14041 aaaaatgatt tagtggctcg tgcaaatgct attagagtaa gaacaaaatg ggattctacg
    14101 tctaagacgg ttgatgaggg agataaagca acctttaaag taactaatac ttatggagat
    14161 cataatttgc atgtgaaatc tgtatctggt ggcggcaaag ctaccataag caatggtact
    14221 ttaactgttg atactacagg agccactgga aacaaaatca ctgtagatat gattaaaggt
    14281 tctcaccctt cagacgcgca ccctacaacg gtatggagta atggttctta tcaaaagctt
    14341 gttaccggtt ctttttacat tagtacttct gttacggtaa atgttaagag aaaaggaact
    14401 gttgaagttt taaaagttga ttcagaaaca aaaaaaccat tatcaggagc aacatttaga
    14461 tttagctact caggtaaaac aaaagatgtt actactgatt cgaatggtaa agcaaaatta
    14521 actgaaaggt tgaaagctgg aactgtagta aaagttaagg agataaaagc tcctaatggc
    14581 taccaactag attcaagcga attttcaatt acagttaaag aaaatcaaaa tgttactacc
    14641 acaagaacca ataagaaatc cacaggttct gtagaaattg aaaagatagg cgatttagat
    14701 ggattaggac taccgaatgt agtattcacg atttataatt ccgataacaa agttgtaaaa
    14761 gataacttaa aaacagatag taatgggaaa ataaaagtcg atgaactgca atttggtaaa
    14821 tattatgcag tagaaaaaca aggtgttact ggttatgatc ccgatggtaa aaaatacaat
    14881 tttgaaataa gtcaagatac tccttttaca aaaccggcta aagtgaaagt aacaaatatt
    14941 tatgaagtat ccataagcga aaaagtatcg gacatgaatg aaagtcaggt attaaaaaat
    15001 aattggtctg ctgatccaaa cgattatctt caatatgaca ttacaactgg aaatctaaaa
    15061 aaatcgggag aaagaaacgt ccaaagtttc attatcgaag ggttttacga caataagaat
    15121 gtagatgtgt caaaaagtga agtatatgtt ggatcaacaa atgtaacaaa ctcttttgac
    15181 attaataacg atactaacaa tggaaaagta attgctaagg cgaagacaag cgtattaacg
    15241 aataatgatt tttataataa gtcctataat ttacggatca ctatgaaaat taaaaaatct
    15301 actcttgaaa acactgaaaa gcaaaaaaat ttaacgattg ttaaaaatag taaagttact
    15361 gtcggttcaa aaatctctaa atctgctagc tctaatgatg tagaaaccgt tttatattca
    15421 agaaaagtta ctatcaatca tattgatgaa aaagacaaac accttttgaa acaagatatt
    15481 gattataaat acgatgggga aacgtatgaa tataaaccta gaaccgattt atttgataaa
    15541 gatggaaaca attataaatc tgatgtaatc cataaaggga aaattgatgg aaaagatata
    15601 gttttaaaca ctccctatca tattccggta ctttctgtga atgtggatcg gattcaaatt
    15661 gatacggcta gagctgttaa aaatggctat ttacctacaa aaatagaact aagtaaaaaa
    15721 gaagaatatg aaaaagaatt agaaaaaatt gtattcaaag ttaaaattac agatatagat
    15781 aacaataaag ttgtttatga tgaaaacttt aaatacaaag aatttaatag tcatatgtcg
    15841 cttgatttac ctacagaata tttaacaaag aataaaaaaa tcaattatag tgttgatatt
    15901 cttttagtgg ataatccaga taaaaacaag ttcgaaactg aaactaaaga tttaagaacg
    15961 atcggttata cttcttctga aaaagtttta acaaacaaag atatgacaaa taaccaagtc
    16021 aactattcag cagtagttag aacagtgaaa gaaagagaga ataataatcc ggtcaaagag
    16081 ttcaatgaga gtatcaatta taaatttact gatagcacta aaacaaaaac aggatatggt
    16141 atatcagttg atttagagcc aacatataga aatgaaattg ggaaacaaat agatatgaaa
    16201 gtctatagtt atccgatgaa tgaattgatt gacagcaaaa ttgacgaaat ctatcaaagt
    16261 gggggaaaag aaacagaagt taagatggat cgcttaaaga atgatggtaa agttgagtcg
    16321 ggtattagta ctcaaaatct ttcattccaa tttccacata tgaatatcga aagaaaaact
    16381 ggaaatatat atgctgacag tcaaagaaat gatgaatcta ttaagtatga attgatcgat
    16441 ggcggtagaa aattatatgt gcctatttgg tgtgatttgg gaaattattc tattgctatc
    16501 aaaagtagta actttggtgg taactatatc tcgttggata tgaaccagaa catagatgtt
    16561 tatgcttata tgtatgcaac gatagatagt gaaacaaaaa aagatgatga attactgctt
    16621 gaacctgttt atccagagtc tactctacca gatggttgga gcaaaaatga gattgattgg
    16681 ctgaataaat aagtttgaaa agtttttatc tatctgatag aattaaataa tgatataggg
    16741 atggtgatag aatgagggtt caaagctatg gtaacagtgt ctttgatgtt aaaagagaat
    16801 ttcaagattc tagaagaaaa accaaaaagc tgatagctta cttcattcta tcagctatcg
    16861 ttttctatat tgtcaagttt gttttggaat taaactcaat agtattcaca gatatggttc
    16921 ataaaatgtt aaatggagaa cctattaatt tcaactttga ttacatgctt gaaaaagcac
    16981 aaagcaatca aattgtggct tttatcgtga gtatctatta ttttattgaa aaatctattt
    17041 tttctttaaa agattttttc tttgaaatgc ttaccaaact aacaacgttt tacaataaaa
    17101 tttcaaaaaa ttaaggagga agtttgaatg ttagatcaaa atacagacag aagttggtgg
    17161 atgattggtg ccgtgatcgt aggtgccatc ttaatcggga cagctaaagt agcttttccc
    17221 gaagtgttta atatcgtcat tacatttttc aaaaacatga tccctacaaa cttaggatag
    17281 ttccactaaa aaattcacgt agtttgatgc gtagaaaaat aataaagaat gaaaaaggct
    17341 acataaagtg atttatgtag cctttttttt ggatggaagt gatgtaatgc taagagatat
    17401 gcccaaaatg attcttttaa tgtttgttgg gttcttttta attttagtga ttgcgtacta
    17461 ttcattaaat ggctatacac aagattcgtc tgtgaaaggt atgcaagaaa cgttaagaac
    17521 tacagcaata gcaaacaggg atgatagtat tcgagtagaa aaaggacgat ttgctttaat
    17581 taagtctgat tttgaaaaag attttaaaga aaaatttggg aaaagtaaaa atctaaataa
    17641 tgaaaccgct gattataaat ttgattatct tacagatggg aaggacggta ttaaagcaat
    17701 taaagtgaag gttgaaagtg gatcaaaaga atatcaagca acttgtattt taaatgttgc
    17761 aaatgattag aggtgtgaaa tttgcgtgtt gtagaggaaa agaagatttc tccaaaaatc
    17821 gaggaaactc ctaaaagtaa aattaatatc gcaagtatta ttaaaaaaaa tggaattaaa
    17881 gaaaactctg aagcgataga aggaaacctt gattttttaa ctaagctttt agaagaagat
    17941 agtggaaatt atgaaccacc aattgaagat gcaaaattaa atatgattcg tgatgattta
    18001 accagaaact attcccaaga agttttacaa gctttaactg atgatgaaat taggcgaaaa
    18061 cttgtacaag ttgttttgaa agaacatggt actttcttta aaaaagataa agaggttgca
    18121 gaatatgtag tacgtgaatg tattggaaca gggattattg agcgaattat gaccaacgat
    18181 gaaattacag atgttggttg gaatggctct caacttagca ttgaaactaa ctctaacaaa
    18241 tggttgtttg acggtgataa attaaatatc acgcaagagt atattgaacg tgttatttct
    18301 aaatatgctg ttgtaaatga tcgggctttt aatagtggta atcctatcat ggatggaatg
    18361 tttaaaaatg ttcgtatatc agctacacac atagataatt caccagatgg ctctacgttt
    18421 tctatgcgtg tggcaaggcc tagattagca ttgaataaag aaaactttga agattttgct
    18481 cctgattata ttttggagct atttgagaaa atgatgaaaa caaaagcaaa tatctgtata
    18541 tcaggggaga caggtacagg taaaacggaa cttcaaaaat tactgctaag ttttattgat
    18601 aatcatgatc gtatgattat gattgaggac gttcaagaaa ctcacgctaa agaattattt
    18661 ccggataaag atattttctc ttggatcact actcccaaaa aagcaatttc agatttagta
    18721 aaagcttctc ttagaaataa tccacgatgg atcattgttt cagaaacacg tggttctgaa
    18781 gcttatgaaa tgcttcaagc ggttttgtca ggtcactatg ttgtaacgac acttcatgcg
    18841 gttaatgcac gtgcgatacc tagacgtttt gtaaatatgt gtgcaagtgg ttttaaaata
    18901 aacgaaaatg cggttgagga agacataaat cgttatttcg attttggtgt ccatatcaaa
    18961 aaaacagtgg ttgatggtaa agtgatccgt tatttgaatg aaattgttga attttctgct
    19021 agtgaaccga ctacagtttt taagcaaaaa tttatcaatg gaaagtttgt cattgaaaat
    19081 ggtagtcttt ccgaagattt taaagaaaaa atggctgaaa aatttattac gtttgaattt
    19141 cctgaagatc aaactaatac agaagaatca cttcctgaag aagaagaggt gatttaagtt
    19201 gaaagtacag gctatgacaa agcgaaaagg tctcatggat gtttcggaac taaacgccta
    19261 tcaagtagcg tatggtaaac cgttagatta tagagattat ttgaactatg ttggattacc
    19321 ttgtttgttt atgggtggct tttcttttgc tttatgttac tactggtgga ttgctttgat
    19381 ttgtggagta attggaggcg tatatggctt taaagttata atgcctaaaa gtattaaacg
    19441 ctcttatgaa ttaaagagtt tacaggaaag aaataaattt attaacaaca tgactcaaat
    19501 tttgaccgat gatagtaaaa cagttactag agcgttatct atagcaaaac agcgaacaaa
    19561 aggtgaatta agagaagata ttcaaatctt agaatcacgt ttacaaggtg ctgataaatt
    19621 tcagattgct gaagcttttc gtgaaatcaa caataaatat tatagtgatg ttgtttttac
    19681 acaatacttt gagcaattgg aaacagctat ttacgaaggt agaaataatt cagatactat
    19741 gaagcaaata aagagctatc ataatgatgt gaaacgtaaa acagaaggtt ttatgaaaat
    19801 caaagacggc tatcttcaag atatgaagca aatgatgttt attgtagctg tttttattgg
    19861 agctataact tttgcttttg gtttttctac tttctatgaa ggttttgctc gatcacctat
    19921 cggatgggta tttggatcta tttacttttt gattatggtt agcttcatga agtcattttt
    19981 caaacattat tttgatgatg aaataatgag tttgggggta agtaattaat gaaagttaag
    20041 gctttaaaaa agaaaagaaa atcaagtatt agccccttga aaattacgaa aacagaacat
    20101 aaaagctttt ggattaaatt actaggtgat gtttattatc aaaaattacg tgaaatgaac
    20161 aattccaata ttgcgattat taagtggcaa aaacaacggt taaaaaagtc attgattttt
    20221 atcctagtcg gattcttaat gtatctattt ttagggaaag aatggtatta cttagccggt
    20281 ggaattgcta cttcagtagg tttttatgtt tggcaagcaa aatcaatcaa tggtatctat
    20341 aatcaatttc ggtttgaacg acacttgcaa tttagtaaat ttacacggct attgatcccc
    20401 tatctgaaac aaaaaaaaga tggcggaaat ttatatggtg tttttgcaaa aatcgtaaaa
    20461 agactagatt atgataccga taaaaagcta ttaatgaagc ttatgcaaga aatgacagat
    20521 cagcctaacg atattagacc ttttacggaa tatgcagaac agacttctgg aacagacatg
    20581 tccgtattat ttatgtctac agtttatgat attcgacaag gttcggcaga tttggatgtt
    20641 attgaagagt tggatcgttt agcttctgaa gagttaatgg ccggaatcga ttcaatcatt
    20701 gactataagt cgaggcgttt tgtcttcttt cctacaaaaa ttgcaatgac ttcatttatt
    20761 ttagttgtcg gttttgcagt aggcgttctt ttcatgaacc taaaagatat taactttggg
    20821 caataaagga aaggagaaag tcaatgcaag aacaatccgt tatggaaatc attaaatggt
    20881 ttataggttt aatgatgatt atggcaatgg tttctatagg acttttttgt gttcaattac
    20941 aagatattaa tactttcaag caacaagtaa attatcaaat tgaacgaaaa ggaggtctga
    21001 cgacagaagc tgttgaagca atcgacaaat attcggctac taattatgat agacgtttta
    21061 caattgaaag cgataagtta aatcagaaag tatcttatgg agaagaaatt gattatacga
    21121 tcaaagcaac tattccaatt caaattttac cgcttcctga tgtaacttta tcgtttaacg
    21181 gaaatagtgt ttctcaaata agatgagagg aaggataaaa tgcaagagaa taatgtttcc
    21241 agaataattt atttgattgg cggattgata attttatcct tagctattgc cggtcttgta
    21301 gagcattggc cggaaataaa gttattaata agaaactttt acgacaataa aatgattaaa
    21361 atgtaggagg tatagatttg gaagcaattc aagaaaatcg taaggataat caagaaacaa
    21421 gtgaaaaaaa caaaaaaaaa agaaaaaaga aagtagataa atttacggaa atgaccgata
    21481 aaatcattga aaagaaagga cttaaaccta aagactttga ccgtcaagca atcaaagaag
    21541 cacgacaaaa actgtatgat gattttgtta aagaaaacat atcacagctt ttagactaac
    21601 atttaggggg aaataaaatg aaaaatttag ttatcagcaa gtttgcaatg ttaccaagaa
    21661 tggatttttt cgataatgta agtaagttta tgtcaaatat gacttcaaaa ctacaaggaa
    21721 tttcactatc tgtaattatc ttttgtattg tggttactgg tttgatgttt cttttcggag
    21781 aagggccaag tcgtactgct aaaaaatggt taacttatat cgtgattggg gcaataatta
    21841 tcttcggagc ttcaactatc ggacaaacga tcaagtccgt tggtggtttc taaggggaag
    21901 cttcttagaa ctaaaaaatt cgcaagtatt gcatgaaaga gcattgagtg attaatgctc
    21961 ttttttattt tgaaaaacta taaactaagg agatttaaac tatgaaccaa cgattcgaat
    22021 ataattttga agatgtagaa cctaagttac tgaaaaaagg aaaaggatta aaaaagaaaa
    22081 ataaatatac tctcaaacaa gcagaagcat tagtaggatg gattcaacac aattggtcag
    22141 acaagacaac aattaccttg atctgttcag acacagaaga aggaacaaag tatgcttttg
    22201 atggaattga aattactcca ttttcgattg gcggacaaga aaaattattg tttcctgata
    22261 ttgaaggaca aattttacaa gcgccggaca gcatgatttc cgatcctaat aaactgattt
    22321 tggatattaa cgatcaatac aaacacgaac cagacgtagc agaaccaaca aaagaatcaa
    22381 agtcaaaatt aaatttgaag ctcccttcag tagtattacc atttgctaag aagaaaaata
    22441 aacttatgaa cgaattgatt gaaccagaag aaacggatat ttatgaagaa gaattagaag
    22501 aacaagaaga gatcgaagaa ttagttgtgt cttctgaaga aacagaagaa gtagaagaaa
    22561 ttgaaactgt ttctgaaaat gaagaagaaa cagaagaaat ctttgacttt gaagatgaag
    22621 aagaagtgga aaatgtacag aaaggcgatc tatctacaag tagtcaaaat gggttggaag
    22681 ctgtaaatga tccacaagtt ccaccatata tatcttcaca aactcccaat tactctccac
    22741 agtatcaagc gcctaatgtc ttacaaccat taagaaaaca cgaaacagtg cagttagtta
    22801 cgcttaaaga gtactgtgat ttgggagaag aaattgaaac ttcaatttct caaatggtcg
    22861 aaaagttgaa accagaatct ttattcaaat tcatagggat tccttctaca ggtcttacaa
    22921 atactcgtat tgatgaatat agaagtaacc atgctatgtt gcgattagct gaagtaaaat
    22981 ttgaaaattt aagagagcat tattcacggc aaattatttc ttttaaagca gaagccctag
    23041 atcgtttaag aactgcggta gatattgctt ggaagaagcc ttacgattta gatgtgaaga
    23101 aaaacaaggc cgaagagtta tcaaaaatgg aagcagaagc agaagctaaa ttaaatgagt
    23161 tcgtgaaacg tcaggaaaac aatgtaaatg ataaaatcaa aaagtttgag atcgaacaag
    23221 aaatagattt aaaaaacttt attgcaagac aagaggcaga taaagcggta tttattgcta
    23281 cagagaaaga tcggactcaa aatttaattg attctaaagc ggaatcaatc aatgcagatt
    23341 tacttgaaac aaaagataaa tttattgatg aagaaatgta caaaatgaaa attgaaatga
    23401 acaaaaattt atttgatggc aagcaaaaaa ttaaatcaga attggctact gaactcgcta
    23461 aggcaaatga taatgtttgg gaaaatgcgc tgaaatttat tcaagaaatt caagatgaaa
    23521 ttgaagctaa aacaccaatt tgggctgctg aaatcaagga gtttaatagt ttagaagaac
    23581 aagaacatga acgtatgaag caaactaaag aacttcaatt aaaagaggaa agtattgaaa
    23641 tcaagcgttt ggaagctgaa atgaatttga agcgtatgga agaattagat catgaaaata
    23701 aaatgcttaa aattaaactt gaaactgccc tttcaaaaaa tgagttatta gctatggaac
    23761 aagatacaaa gcaagtggtg aatggatcaa acagagttgg tgcacttaat ttatttagta
    23821 aacgttaaag gagaacggat atgagtgttt ttaataataa agttatgtta gggaactgtt
    23881 atgtgaacca cattggtttt tacgatggag gaacatacag agttttattc ttacgtttat
    23941 ctgtttttag ttactcaaaa gatggaaagg ggcattatga aaatattaat gcacaaattt
    24001 cttgtccttt agatagaaat ggggaaacca cgactacaag tagtcaccct aaagccttga
    24061 tgaataaatt tatctttgaa aagttggatc gcaatttggt tgaggggatg aagataagta
    24121 ttcatggaaa tattcgtgga acagaacaag tgcttcttaa cagtggttgg aaaaactttg
    24181 gtcaattatc gcctttagaa aaagaagaat atcaaaaaat tcctaaaaat gaattagtaa
    24241 caagaaatca aacatatatc tatatagaag aggtaagtat gccagaaaaa gaagaattta
    24301 gaaagtctca atctaaggta acaaaagaag atgtggaagt tgcagaaccg aatcaagcag
    24361 atgaaatttt atccgatgat actgatccag tgaatgatga aggagaggtt attgaagttt
    24421 ttgaagctga aattatcgaa gaggaagaag aaattaaaag ttttgataaa agaatgtatc
    24481 gagagaaacc aaaaggttat gtgaattttg aagatatgta ttatgacgaa tattctaatg
    24541 aaccaccgat caattagtgg gggtcaaata tgaagctagt acaaaacaat gaagtgaaag
    24601 aaataaaaaa cggctttgtt aaaaactcga acaaaatttt gggaaagctg aaaaaagtag
    24661 gtagtttcaa aaaaaataaa tatcatactg gaaaaattga gggagaagat ttaccaaaaa
    24721 gtttacaaga taaattgaat gttccgcttg tatttatagg tgttttttta ggttcaatag
    24781 tttttctagc aataacgtac ttattgaact ttttaaaagc tttgttagtt gcaatcggac
    24841 agtcagaaag tgggctactt ggtgtagagt tcgatcctaa gtttagtttg gcatatctaa
    24901 aaccacttgg ggatacgaaa caatacttta tgtgtgctgt ggttgcggta ataggagtcg
    24961 cttatttaat atatgggaaa ttaaatcatg aaagtgagaa aaatcttgtt tacggtcaaa
    25021 aaggagattc aagactttca actatcaaag aaattaagag agattaccat gagataccag
    25081 aaaaaacaga agtgtatgat ggtattggtg gtgtgccaat tagtcactat caagataaat
    25141 attatattga tagagacaca gtaaataccg ttgttttggg agcttcacga tccggtaaag
    25201 gggaaacatt tgttgttcct ttattagata atcttagccg agcaaaaata caaagtaata
    25261 tggtcgtgaa tgatccgaaa ggagaattgt ttagcgcttc aaaggaaaca cttgaaaaac
    25321 gaggttatcg tgtattagtg ctaaatattg atgatccact tgaatcaatg agttttaatc
    25381 ctttacaact agtaattgat agttgggcta acaaggacta tcacgaagct agtaagcgag
    25441 cgaatacttt aacttcaatg ctctttgctt caggaatgag tacagataat gagtttttct
    25501 ataaatcagc taaatcagcg gtcaatgcga ttattttaac gattgtagaa cactgtttta
    25561 acaatgattg cattgaaaaa attacaatgt acaacgtggc tcaaatgctg aacgaattag
    25621 gaagcttatt ttacactgat ccaaagactg gaaaagaaaa aaatgcttta gatgaatatt
    25681 tcaatacttt accacaaggg aatcaggcca agattcagta tggttctact tcatttgccg
    25741 gtgataaagc caaaggttcg attttatcta ctgcttcaca aggtattgaa atgtttacaa
    25801 gtgatttgtt cgggaagtta acaagtaaaa tgtctattga tttgaaagag ataggctttc
    25861 ctaagtccat acaatttaaa gtcaatacga atttagttgg aaagaggatt agtatttcat
    25921 ttttgagaaa agaaaatgat gtaattagat taattaagaa gtatcgagtg aaagtaaaag
    25981 ctttagggct atgtgtttta aattttaatg aatatcttca ggatggagat atgttggata
    26041 tacgatatga agaagagaaa tcgagagcat ggtatcgtat tgaatttccc aaaaaacaag
    26101 caaatagtca tgatacttct ttagtcacta aaaaattcaa gtcaggtaaa aattattctg
    26161 acttagaaat cagcacctta cgattaaaat acacggatca gccaactgct gtgttcatgg
    26221 ttattccaga ttatgatccg tcaaatcacg tacttgcaag tatttttatc agtcaacttt
    26281 atacagaatt agcaagtaat tgtaagcaaa caccggataa aaaatgtttt aggcgagttc
    26341 atttcttgtt agatgaattt gggaatatgc cggctataga caatatggat gggattatga
    26401 cggtatgtct aggaagaaat atgctttttg acttagtgat tcaatcctat agtcagctag
    26461 aaacaagata tgataaagct tttaaaacaa ttaaagaaaa ttgtcagaat catattttaa
    26521 tcatgtcgaa cgatgaggaa gggagcgtca ataattttgt gtaaataaat tgtcctcctg
    26581 caaaataatt agttactcag taaacattga aactaatgta tcggttacct gttgaaaacc
    26641 tttatggctt ctgtttagaa atttttgatt gtatgtatca aaaatgctga ctagaaagcg
    26701 ttctagtgat tcttcatttt gaaactgctc ttttctacgg ctgtatcttt taatttgctt
    26761 attgaaagac tcgattagat tggttgagta aatggttcta cgaatgctag gtggaaaatc
    26821 ataaaaagtt aataagtctt ggttttctat gagtgactgc gtcactttag gatagttttt
    26881 cttccatttc tcaatcatgc cggataagaa ggtattcgct tcttcttttg agttagcttg
    26941 ataaacagcc ttaaagtcat cacagatttc ttttcggtct ttgacacgta ctttatgagc
    27001 gatgttacga gatacatgga tacaacaatg ctgatatttt gctttaggat aaatttgatg
    27061 gatagtatct ttcatgcctt ttaagccgtc cgtaataaaa agcaagactt cttgaactcc
    27121 tctggagtta atatcctgta gcagctcatt ccaaacgtat gttgattcag ttggagcaat
    27181 cgcataactc agtacttctt tagtgccgtc ttctcgtata ccaatggcaa tataaatcgc
    27241 ttctttggat acggtttgac gttttagtgg aatgtaagta gcgtccataa aaatagcgac
    27301 atacttatca tttaaggctc tggatttaaa ggcatttact tcttcagtca gaactttagt
    27361 catgttggac atggtttgtg gagtatagtg atgaccgtac attttttcga tcaaatcagc
    27421 aatttcagac atcgtaacac ctttttcgaa taaatggata atagtggttt ccaatgtatc
    27481 gtttgttctt ttgtaggctg gtaaagtttg ttgtttaaac tcaccattac gatctctagg
    27541 tatttccaat gttaattcac catattcggt tttgattgat cgaaagtaag aaccgtttct
    27601 cgaattacct gaattaaaac cagtgcgatc atatttttcg taatctaaaa aagccgttaa
    27661 ttcagtccgt aggagtgtgt ttatcgcttt ttctaagtgc gaacggaata attcatttaa
    27721 atcgccttta gtgactagag tttgcacaat ttctgtagta aaatcattca tagggaagtc
    27781 ct
//
LOCUS       DADVXM010000030        27636 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.031, whole genome shotgun sequence.
ACCESSION   DADVXM010000030 DADVXM010000000
VERSION     DADVXM010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.031"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            61..1320
                     /gene="lysA"
                     /locus_tag="KB927_001367"
     CDS             61..1320
                     /gene="lysA"
                     /locus_tag="KB927_001367"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBB6840293.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1307..2107
                     /gene="dapF"
                     /locus_tag="KB927_001368"
     CDS             1307..2107
                     /gene="dapF"
                     /locus_tag="KB927_001368"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBB6840294.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2110..2991
                     /locus_tag="KB927_001369"
     CDS             2110..2991
                     /locus_tag="KB927_001369"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBB6840295.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            2988..3704
                     /locus_tag="KB927_001370"
     CDS             2988..3704
                     /locus_tag="KB927_001370"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBB6840296.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3710..4405
                     /gene="dapD"
                     /locus_tag="KB927_001371"
     CDS             3710..4405
                     /gene="dapD"
                     /locus_tag="KB927_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBB6840297.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4421..5422
                     /locus_tag="KB927_001372"
     CDS             4421..5422
                     /locus_tag="KB927_001372"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBB6840298.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5419..6780
                     /locus_tag="KB927_001373"
     CDS             5419..6780
                     /locus_tag="KB927_001373"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBB6840299.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6740..7891
                     /locus_tag="KB927_001374"
     CDS             6740..7891
                     /locus_tag="KB927_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBB6840300.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7866..9035
                     /locus_tag="KB927_001375"
     CDS             7866..9035
                     /locus_tag="KB927_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6840301.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9210..10589
                     /locus_tag="KB927_001376"
     CDS             9210..10589
                     /locus_tag="KB927_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6840302.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            10870..11667
                     /locus_tag="KB927_001377"
                     /pseudo
     CDS             10870..11667
                     /locus_tag="KB927_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            11856..12524
                     /locus_tag="KB927_001378"
     CDS             11856..12524
                     /locus_tag="KB927_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBB6840303.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(12724..13110)
                     /locus_tag="KB927_001379"
     CDS             complement(12724..13110)
                     /locus_tag="KB927_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840304.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(13082..14464)
                     /locus_tag="KB927_001380"
     CDS             complement(13082..14464)
                     /locus_tag="KB927_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6840305.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(14620..15807)
                     /locus_tag="KB927_001381"
     CDS             complement(14620..15807)
                     /locus_tag="KB927_001381"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBB6840306.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(15814..16845)
                     /locus_tag="KB927_001382"
     CDS             complement(15814..16845)
                     /locus_tag="KB927_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6840307.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(16861..18315)
                     /locus_tag="KB927_001383"
     CDS             complement(16861..18315)
                     /locus_tag="KB927_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6840308.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            18490..19395
                     /locus_tag="KB927_001384"
     CDS             18490..19395
                     /locus_tag="KB927_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6840309.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            19486..20163
                     /locus_tag="KB927_001385"
     CDS             19486..20163
                     /locus_tag="KB927_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBB6840310.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            20160..20330
                     /locus_tag="KB927_001386"
     CDS             20160..20330
                     /locus_tag="KB927_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840311.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            20444..21340
                     /locus_tag="KB927_001387"
     CDS             20444..21340
                     /locus_tag="KB927_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6840312.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(21395..22765)
                     /locus_tag="KB927_001388"
     CDS             complement(21395..22765)
                     /locus_tag="KB927_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6840313.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            23003..23749
                     /locus_tag="KB927_001389"
     CDS             23003..23749
                     /locus_tag="KB927_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6840314.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            23746..24585
                     /locus_tag="KB927_001390"
     CDS             23746..24585
                     /locus_tag="KB927_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6840315.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            24586..25536
                     /locus_tag="KB927_001391"
     CDS             24586..25536
                     /locus_tag="KB927_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBB6840316.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            25677..26429
                     /locus_tag="KB927_001392"
     CDS             25677..26429
                     /locus_tag="KB927_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840317.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            26448..27599
                     /gene="queG"
                     /locus_tag="KB927_001393"
     CDS             26448..27599
                     /gene="queG"
                     /locus_tag="KB927_001393"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBB6840318.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         9070 a         5033 c         5819 g         7714 t
ORIGIN      
        1 aatctttatc aaatgaaatt ccaataaaaa cggaaaaaaa gtgaaaagag gaatgaaaaa
       61 atgacagaat tgataattgg cggagtcaca gcaagcacat tggcagaaaa gtataagaca
      121 cctctgtatg tgtatgatga agaaaagatg agacaaacga tgctgtcatt caagcgaggc
      181 tttgtatcga aacgttttga tacaaaagtg ctttacgcct ctaaagcatt ccaaacgatt
      241 gagatgctgc atttagttcg tgaatatgga ttcgggctag atgttgtcag tggtggggaa
      301 atctataccg ctttgcaagc tgattttcct agagatacta tctacttcca tggtaacaac
      361 aagacgccag aggaactgat ctatgcactt gaaaatgatt tgttgcatat tgttgccgat
      421 aatttgatgg aagttgaatt attagcagaa ttaagccaac gctatttaaa aaaaatctgt
      481 atcatgcttc ggttgaatgt cggagtagaa gcacatactc atgaatatat cgtcactgcg
      541 catattgatt caaaattcgg catgagctat gaaagtaaag agtgccaaca agcccttcag
      601 ttgataaaag aaagcagcta tctagagtta gaaggatttc atgctcatat cgggtcacaa
      661 atttttgatg ttactgcttg gttagctgaa atcgacaaat tgacgaatta cttaaccgat
      721 tttgaccaac ctctttcctt gaatcttggc ggagggtttg ggattcgtta tacacaaaat
      781 gatcagccga tcccagtcga agaggcacta aaaaaactga ttgaatatac ggaagaagct
      841 ttggaaaaac gaaaactgac cattcgtcaa ttactgatcg aaccgggtag aagtattgtt
      901 ggagaagctg gtacaacact atacacgatt ggtttcatca aaaagacacc acataaaaaa
      961 tattactttg tagatggcgg gatgacagat aatatccgtc cagctctgta tcaggcagaa
     1021 tacgattgtg atttagcagc aaaactgtcg gaagaaaaaa cagagaaagt gacgattgca
     1081 ggaaaaatgt gtgaatcagg cgatgtggta attaaagaag cttatttgcc gaaagcagaa
     1141 tcgggtgatc ttttagctgt ttattccacg ggagcttatg gatactcgat gagcagcaac
     1201 tacaatcgag cgacacgacc agcagttgtt tttgtcaata atggccaatc aagactgatt
     1261 gttcgcagac aagcattttc tgatctacta aggggggaag tttcctatga tccttcataa
     1321 atataatggc tgcggaaatg attttatctt attagattac gcagaagaca cagattatag
     1381 tcaattagcc gcttctttat gcacaaaaga aaaatatgat atagacggat tgatcgccgt
     1441 aaaaatcgat ccgttggaaa tgatctatta caacaaagat ggcagccgcg cgccgatgtg
     1501 cggaaatggc attcgctgtt ttgctcgata cgtaaatgat cagaacatga tgaatgaaca
     1561 ggaattcaac gtagagacat tagcaggcac aagaaaaatt acggtgttgg atccctcacc
     1621 tttttattgc agcgtagata tgggagtgcc agatgattct ccggaaaaaa tcaaagctaa
     1681 tcaaacttat ccaataaaaa accaggaaat agagatcaat ggtgaaaaag taacgatcac
     1741 tagtttattt ttaggaacga ttcataccgt tgtttttgtt gaaaatgcgc gtgaggaagt
     1801 ctggagaaaa agaggtgaac tgatctgtca tcatcctttg ttcaaagaaa aaaccaatgt
     1861 caactttgta gaagtagtca atgaacaaga attgatcgtc cgtacctatg aaagaggagt
     1921 aggttggaca cttgcttgcg gtacaggttg ctgtgcctct tatgtggttg ctaaggaaac
     1981 tgggaaaatt tcagcagatc aggtagttgt tcacttggaa caaggagact tgatgatctc
     2041 tggtgaggat gcgatacaaa tggctggccc agcagttcat gaatggacaa gaatattgga
     2101 ggaatgaaga tgataaaagg ttcgatcgtg gcgctgatca cgccgatgaa tgaagaggga
     2161 tcagtagatt atgctggttt ggaaaaattg atccaattcc atttagatga acaaacagat
     2221 ggattattag ttttaggtac aacaggagaa tcttctacgc tcacacaatc tgaggaggag
     2281 cagatccttc aactgacagt aaagaaagtg gctggccgtg tgccggtgat tgcaggagct
     2341 ggaacgaata atacgaaaga aacgattgaa aaagcgaagc attttgcttc tttgggggca
     2401 gacgcacttt tggtcatcac cccttactac aacaaaacaa gtgatgcagg actagctgct
     2461 cattttacag caattgcaga agcctcaccg attccgctta ttttgtataa tgttccttct
     2521 agaacaggca tgtcgattcc aatccatgta ttagtaaatt tagcagaaca tcctaatatc
     2581 attggtttga aagaagcctc aggagatatg gcttatgtga tggatgccgc tcggttgatt
     2641 ggagaagaat tcttccttta cagtggaaat gatgatttga tcctaccagt aatgagtgta
     2701 ggaggaagcg gtgtaataag tgtatgggcg aatatccaac ctaaaatagt ccatgaatta
     2761 gtaaaagata cgcaggacgg aagatggcag caagcaaaag aaaagcaatt aaatgcactt
     2821 gaactgatcc atgccttgtt cagtgagacc aatcctattc ctgtcaaagc agccatgtca
     2881 ttattagact taccttccgg acctctacgc ctgcctttag tttctctttc aaaagagaaa
     2941 aagaaacaat tagctcagct tttgttaaaa gaaaggacgg ttgaaaaatg aaaatcggac
     3001 tgattggcag tggacagatg ggaaatagag tcgaagaagt tgcacaagaa agaggagata
     3061 cggtccttct tttacggacg gcacctaaag aagcaactac gcttgctttt acggaactgc
     3121 cagaactgct tattgatttt tctcatccag ataatttaga gaaaatcctt tcgtatagct
     3181 tatcatatca acttccgtta gtcattggca cgacaggtta tacacaatca cagttccaag
     3241 aaataaaaga acatgccaaa catgtacctg tgatgtatag tgctaatttt tcgttcggca
     3301 tcatggtgat gaatcaacta atcaagcaag cagctgcaat gttgcaaggc tggcagatcg
     3361 aactgattga aaaacatcat agtcgtaaaa aagatgcacc atctggtact gcaaatatgc
     3421 tgcttcaaac aatccaagaa gtgcaaaagc tgcagcccgt atacaactgg caagggaaaa
     3481 aaagagaaga aaaccaaatt ggtgtacaca gtattcgtgc aggttcttta cctggtgaac
     3541 atgatgtatt gtttgctgct actgatgaaa tatttacgat caaacatgaa tctttttcta
     3601 atcgaatctt tgctgcaggc gcagtagaag cagcggactg gttgaaagat cagtcaccag
     3661 gttattacaa attagaagat ttattaatgg acaaaggggt gtaaaaaacg tggaagctca
     3721 agaaatcatc cgctacattc aaacggcatc taaaaagacg cctgtgaaag tctatctgaa
     3781 tgtaaccgag ccaatcgaat ttaaagaaag taaagttttt ggtgaaggaa gcagcttcgt
     3841 tgtttttggt gactatgaga cgattgctcc ggttttagaa gctgaatcag aaaaaatcat
     3901 tgaaatcgaa atcgaaactg ctgcaagata cagcgcagtt cctttgctag atattaaaaa
     3961 aattaatgct cgtatcgaac caggtgctat tatcagagat caagtgtcaa tcggcaacaa
     4021 tgccgtgatc atgatgggag cgattatcaa tattggtgca gtaatcggtg aaaacacgat
     4081 gattgatatg ggtgctgtct taggtggacg agcgacagtg ggcaaaaact gccatattgg
     4141 tgcaggagct gtcttagcag gtgtgatcga accagcatcg gccaaaccgg ttatcgtaga
     4201 agacggcgta ctggtaggtg cgaatgcagt gattgttgaa ggtgtccata tcggaaaaga
     4261 tgcagtcgtg gcagcaggag cagtggtttt agaagatgtg gcagcagaaa ctgttgtcgg
     4321 tggaatacct gcacgtgtat taaaaataag tgatgatcag acaaaagaaa atacagcatt
     4381 gattgctgcg ttacgcgaat tatagaggag atggagaaaa atgcgcgaaa tagatacctg
     4441 tattgtgggg gcaaccggat tagtcggcca aacgatgctc aaagtgttag aagaatatga
     4501 ttttccagta ggacgattga aattattagc ttcaaaacgt tcagccggta aagtttgtgt
     4561 attcaagaaa aagaaacaca ctgtacagga attgacagaa acttcatttg aaggatatga
     4621 tttagcgcta ttttctgcag gtgcttctgt atccaaagag tttgcgccaa tcgcacgaag
     4681 tcagggacta tttgtcatag ataattcctc agcatggcgg gaagattcgg atattccatt
     4741 aatcgttcca gaggtcaatc tggaagacta tacattgaat cggctgattg caaatccaaa
     4801 ttgttcaacc attcaagcgg tacttccgct taaagcttta caagaagcct ttggtatcca
     4861 gcgagtcaat tattcgacct atcaagcagt ttctggttcc gggcaaaaag gcattgaaga
     4921 tcttcatcgt acgcaaaatg acgaggaacc agttttgtat ccttataata ttagccaaac
     4981 ggtgattccg gaaatcgatc agcctttgga aaatgggtat acaaaagaag aacagaaaat
     5041 gataaatgag acccgtaaga ttctgcatca gcctgctttg ccagtatcag caacctgcgt
     5101 acgtgtgcca atcgaaaatg gacatggagt ctctgtggca gttcaactgc aaaaagagtt
     5161 tacgacggaa gaaattagag agtgtctcag ccagtttcca gggattcaat tagaagatga
     5221 tctagcagca cataaatatc cgacgagcat tcttgctaga ggaacagata tggtttatgt
     5281 tgggaggatc agaaaagaca cttctttaga gaacggattg ttgttctata cgactgccga
     5341 taacatacgc aaaggagccg ctgcgaatgc cgtacagatt gctgcagctt taatgcagaa
     5401 aatagcggag gtggcaagat gagtaatacg ctgaaagtag cgaaattcgg cggaacatcg
     5461 atgtctcatg aagagcaatt caaaaaagtc cgtacaattg ttctttcaga tcccaatcgc
     5521 caagtgatcg ttgtttctgc tttaggcaaa cgtacgtcag atgatgacaa agtaacagac
     5581 ttactttatt tgatttatgc ttaccttcag catcatgttg attggacacc cctttggaaa
     5641 aggatttgtg atcgtttcat tcaagtaaga gatgttcttg ccctgcagtt acctattgaa
     5701 gatgaactag cacgcataca gaaacaactg gaagacgaaa agataactga agattattta
     5761 gtaagtagag gtgaatatct gactgctcaa ctgatggctg agtatcttgg ttaccagttt
     5821 attgacgcaa aagacctgat tttctttgac tatgatggga aaatcgatca ggaaaaaaca
     5881 gcacaggaaa tcacaaaagc atttaaaaga tatccgaaaa tggttgttcc agggttttac
     5941 ggggcgaacc ctgcaggaaa agaaaaatta ttgggccgtg ggggaagcga cattaccggc
     6001 gcgatactgg cgaagatgtt gcaagcggaa agttatgaga attggacgga tgtttcagga
     6061 atcatgatgg ctgatccgcg aatcatcgat catcctaaaa tcatcgagga aatctctttt
     6121 agagaactga gagagatggc ttatatgggg gctaacgttc ttcatgaagc agctgttttc
     6181 ccagttcaag aggctgatat ccccatccaa ataaaaaata ccaatgatcc tttcgctcaa
     6241 gggacaaaaa tatcgaatca cgaaatagaa aaggaaaatg gactgacagg aatagctgga
     6301 cgcaaggatt ttctttccat cactttattc aaacgtcata tgtccgatga aatcgggttt
     6361 atctggaaag caatgagcat ttttgctaaa catgagatat caatcgaaca tattccttca
     6421 gggatcgaca atatcggagt gatcgtctca gcagaagcga ttgccgataa gttatttctc
     6481 atcacgaaag aattaaaaga aacacttggc gtggaagaaa tcgtcgtgat cgaagactta
     6541 gctttgatct ctgtcgttgg gggtccgcat aaagaattga ttggattatc tgggaaagtg
     6601 ttatcgatat tgaacaaatt agaaattcgc acatcgatct tatcacaagg agcacaggag
     6661 ttgaatctga tcatcggtgt accgaataat caatatgaaa cagtagtgaa gggtatctat
     6721 gaagggatgg tgaatacgga tgctgaaaga atatcgaatg gcactccatc aaattcctga
     6781 aatcgggttt catgaattca agacaaaaaa atatttatat gaacaagtaa aaaacagcga
     6841 ggccgttatc catgaaatcg gcgaaacagg actactcctt tattttgata atcagcaaga
     6901 agaaacgatt gcttttcgaa cagatatcga tgcactgcca gtcaaagaag aaacgaatct
     6961 ctcttttgct tctaagcatg aaggttatat gcatgcatgt ggtcatgacg gacatatggc
     7021 gatgctttta gggttgactg actttataac taaacacatt gaggatctta tttataatgt
     7081 agtactgatc tatcagccat cagaagaaat ttccggtggc gcacaaagcg ttattcagtc
     7141 aggattgttg gataaatatg aagtacaagc aatatttggc tttcatctat ggcctggact
     7201 agctaaggga gaagttttct ctcgaccagg acctttgatg gcacaaagca gtgaaacaga
     7261 cattatcatt aaaggccagt ctgcacatat tgcttctagt gaaaaaggaa tcgatagtct
     7321 ggaggcagct gtacgatttt tgaagaatgt ttatgatttt gaccggcaat taccggcaga
     7381 gtggaatcat ctaatgaaat ttggccaaat ccaaggtgga acgatccgaa atgttttagc
     7441 tggagaagtt attgtatccg gaagtatccg ttcttacagt tcagatatgc aaaattattt
     7501 gaagagggga ttagaccatt tagcagaaca gtttcactct acagctacta tttcttttcg
     7561 ctataatgac ggctatccag ctgtaatcaa ccatagaggc ttatatgcag cactgttaga
     7621 ttcaaacaaa ctacatgaat tagatgctcc agttcttcaa gccgaagatt ttggcatata
     7681 tacgcaacaa tatccatgtg tatttttctt tttaggtgtc ggtgataccc ctgctttaca
     7741 tgatccgacg ttcgattttg atatggatgt tttagaaaat ggtgtagaat ggtacaaaac
     7801 gattcttttt acagaaaatc ttcttgtaaa aatcgatagc agttcaaaag aggagcgagt
     7861 aaataatgat gaatttatcc aatcgattta gtcctaggct ttctagaata gaagtatcaa
     7921 aaatacgaca attcgatcag caaatatcgt cgataccaga tgtgatcaaa ctcaccctgg
     7981 gagaaccgga ttttccaact cctgaacatg tcaagcaagc aggaatagca gcgattgaag
     8041 aagacttttc tcactatacc ggaatgagag gattagagga actgcgggaa gcggcttgta
     8101 tatttcagca acagcgttat ggattaactt atgatccgca aacggaagtt ttgacgacag
     8161 ttggtgcaac ggaagcgatt gcctctgcgt tgttatctgt tttggaagaa ggagacaagg
     8221 ttcttattcc agcgcctgct tattcaggat atcagccatt agtggaacta gctggtgctg
     8281 aattgatccc gatagatact tctgacacag ggtttgtctg tcagccggaa caatttgaac
     8341 gagcatttga acaatatgga tcagctgtca aagcagtcat tttaaactat cctaacaatc
     8401 ctactgggac gacattgtct gcaaaacaat tgaaagcaat cgctgaggtt ttaaaaaaat
     8461 atccggtatt tgttataagt gatgaagtat atgctgaatt gacttatagt ggaacgcata
     8521 tgtccatagc tacttatctt ccagaacaaa caatcgtgat aagcgggtta tccaagtcac
     8581 atgcgatgac tggttggcga gtgggcttta tttttgctca aaaagccctt attgacgaac
     8641 taattaaagt ccatcaatat ctggtgactg ccgctacaac gatgtcgcaa aaagctgcgg
     8701 ctgaagcgct aataaatggg gtgaaagata gcgagaatat gaaagagcaa tatcaaacac
     8761 gaagagatta tctggtccag caattggcgc ctttaggatt tgaagtgacc cagccaaacg
     8821 gtgcatttta cttgttttgc aaactcccag ctgccattca aactgactct tggcagtttt
     8881 gtgtagaatt agcggaacag gcaaaagttg cgtgtatccc aggaattgca tttggcccag
     8941 aaggagaagg ttatatccgg atttcttatg ctagcagcat ggaaaaatta catgaggcct
     9001 gcaaacggat caaagacttt ttaacagaac agtgattcat agattttatc aaaaaaacaa
     9061 tcgttaattt tgcggtatat tctgcaagga gacgattgtt ttttaaattt agttcaaatg
     9121 aacgcgtttc ttttgattca taactaatgt aatgttaagt ttaaattgtt tagaatgatt
     9181 ttaaaagaat attcaaggag gtttcatcaa tggaaaaaat caaagttgtc attgtaggtg
     9241 catctcatgg agggcatcaa tcgatcttgg aactattgac acgatacggt gaaaatgtag
     9301 atatcacgct atttgaagca ggagactata tttccttcat gtcatgtggt atggagctgt
     9361 atttagaaga caaggtaaca gatgtaaatg atgtacgtaa tttcagacca gaaaactttc
     9421 cgcaatccaa tgttcatatt ttaaataatc acgaagtaaa aacgatcgat gccgataaaa
     9481 aaacagtaac ggttactagc gcatcagata acgaaacaaa agaatatcct tatgacaaat
     9541 tgattttgag ttctggtgtc aaaccaaaca atctgccagt accaggagca gatctagaaa
     9601 atgtctactt gatgcgtgga tacaattggg caaccaaaat caaagaaaaa ttaaatgatc
     9661 cggctattaa aaaaatcgct gtcgtaggtg cgggttacat tgggatcgaa gcagcagaag
     9721 caagccgaaa agctgggaaa gaagtcgtat tgcttgatgt gatcgataga cctttaggca
     9781 cttatttaga tgctgagatg acagatattt tagaacaaca cctaaatgaa aacggtattg
     9841 aagttttgac aaatgcaaaa atcgaagctt ttactggtaa cggaaaagtt gaggcaatca
     9901 aaacaagtga aaaagaaatc ccagcagatc tagtcattca agctgccggt gtgaaggcaa
     9961 atacagaatg gttaaaaggg atcgtcgact tagatgaacg tggctggatc caaacaaatg
    10021 aatacttgca aacgaatctt ccagatgtgt atgcagtagg agatgctaca cttgcttatt
    10081 ctatcccagc acgcaaaaaa atgccgatcg ctttagcgac tgttgcacgt agagaagcac
    10141 gttatgtagt aaaacatctt tttgaagaag taccaaacaa accgttcggc ggagtcgtag
    10201 gttcctctgc attaagtgtc tttgactatc attttgcagc aagcggattg aatagcttta
    10261 cagcagcaaa agcaggagta gatgtacgag tgtcttatta tgaagatacg ttacgaccaa
    10321 aatatgtacc agaagaacaa ggaaatccaa aagtgtccat ccaattattc tcggatccaa
    10381 tgacccatca attgctagga ggagcagtat tatctaccta tgatgttaca ggtcaaggaa
    10441 atgtattggc actagcgatc caaaacaaac tgactttaga agaactagca gaagctgact
    10501 tcttcttcca gccaggcttt gaccgacaat ggagcatgtt gaatctagcc gctcaacaag
    10561 cgttaggaga agaaccattt gtagaataag aaaacgaaat atttgaaaag aggttgtgaa
    10621 aaagctgcct tgcatcaagt aataagaaca gccaagtaaa aacagcttct tatgttttta
    10681 acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt ttcaaaaaag
    10741 ggactgtgac acgatttgtg taccgacccc caaaagttag accaaaaaat ctaacttttg
    10801 gaggtcggta ttttttatgg ttaaatatac ttttgaactt aaattaaaga tcgttcatga
    10861 ttatttggat ggcaaaggcg attggaccgt aaaaatccag atcaagagat tgaagcggaa
    10921 atgcttaaaa ttcgggagaa gcacaaggat tatggctgtt tacggatgac caatgaacta
    10981 agaaaccgcg gtttctctat caataaaaag aaagttcagc gcttgatcaa gaagctagga
    11041 ataaaagtaa cggcatacac gcgtaaatca cgtcgctaca attcttatcg aggaaaagtt
    11101 ggagcagtag ccaaaaatcg gatccatcgt cgtttctaca ccagtatctg ccatcagaaa
    11161 atcacgacgg atacaactga atttaaatac catgaagtgg atgccaaagg cattatccgt
    11221 caaaagaaat tgtatctaga tccttttatg gatatgttca atagtgagat tttatcctat
    11281 cgtatctctg aaaagcccaa tgcattagcg gtaatggaag gtttggagga agctatccag
    11341 accactaacg attgtcccta tcgtcgtacg tttcactcag atcaaggttg ggcgtatcaa
    11401 atgaaagctt atagaaacaa attgaaggag tacaaaatct ttcaaagcat gtctcggaaa
    11461 gggaactgct tagataattc acttatggag aatttttttg gcttattaaa acaagagatt
    11521 tttcacggga aagtttataa ctgtttcgag gaattaaaat cagccatcga tagctatatc
    11581 tattactaca ataatgaacg gataaaacag aaattaaact ggcaaagtct cgtccaattt
    11641 cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa aaaaggagtg
    11701 gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca cagtcctttt
    11761 tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga gaaagcatat
    11821 ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt acaatgaaac
    11881 tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag aaatccatgt
    11941 cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc ttagaagaat
    12001 caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg ctttgggcag
    12061 taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat cgttgggtca
    12121 aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag ttgacaaata
    12181 accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc ttttttcttg
    12241 aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg aaaaaatcag
    12301 atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag cataaagtgc
    12361 ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa gaaggctatg
    12421 cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc tacatactaa
    12481 ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac agaggttgtg
    12541 aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc tctgatatct
    12601 aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc acaaaaattt
    12661 aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt ctgtcacaac
    12721 ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta cgtcttccca
    12781 caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa tgaagtgccc
    12841 ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa tgattactgc
    12901 tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg tcatttgttg
    12961 tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt ttgataccgt tgactagttc
    13021 ttccatcgca aaagcagtcc cccattttaa tccaaatggc cgatctcgat actcgttata
    13081 gtcaatgaat ttttttgctg tccgtctcat cttttccacc ttctaatcca ctcataccac
    13141 ctgcatgccc gccaacgaga gaactacgtg cgatggcgcg tcctccttgc aagagactat
    13201 gcgcatggat gattgattga aagccgtatt tttttctaat cgtatcgaca acaaaatcaa
    13261 ctttcgcttc atttatctgc ttttcaggat cttcaaaaag gttaagctgt aaacctgtcg
    13321 cgtatacgag gtcggaacag ttcacgccta cacgccgaat atcctggtag tggtaatgct
    13381 ggtggaaaat ggtcaataaa gcatctgcta gatctctgct agcatttgtc gcttcgattt
    13441 tcatttgctg gtgaaacccg gtcttgccat ttggatcaag atagcctaaa gagtatccta
    13501 cccataagct gactacttgt gtttttgctg cagatcgtct caagcgagtg ccgacttggt
    13561 cggccatttc tttgataacg atctcgattt cttctcgtct tgtataatct ctatctagga
    13621 tttgactatt tccgatactt tttgattttg gtgtatattc ttgtcccaaa aaacttcgat
    13681 cgatgcccca agcatgggca taaagctgag taccgatgac ccctagcttg cttttcaagt
    13741 gataataatc cgcgtgagct aaatcataaa cagaatgtat acccatttgt ttcagacgtt
    13801 ttgctgttcg tttgccgatt ccccaaaagt cagtgatatc tgagattttc cataactttt
    13861 ctggtacatc ttcataacgc cattcagcaa acatttgctt tccgtctttt gagccattgt
    13921 ctaaggctag tttagcaagt agcgggttat cgccaattcc tatagtcgtg tagattccgg
    13981 tctgctcaaa cacatcttta tggatcagtt tagccatgtc gtacgcattt gttttaccaa
    14041 agagtgccat gctatttgtt acatcaagga agctttcatc gacggaatag acatgatggt
    14101 tcgcttcgtc tgcatatttt ttatagatag aattgatttc tctgttcttt tccatataat
    14161 aggccatcct tggggcaaca atatataaat cacttggata ggggaaggga agatctctgg
    14221 cacggctgat attggtgatg ccgtaagctt tttttgctgc aggactggaa gccaagatta
    14281 atccgctacc ccgtgtttct gtcgaatcgg acggatagga catgactact aatttagttg
    14341 taaggggatc aagatccttt tcaacgcact ctacggaggc gtaaaaagat ttgcagtcaa
    14401 tacataaaat atctcttgaa ggttcttttt cataaacaaa taccggattt tgattcgccc
    14461 acataacaat cacctcttca acacaattag aacacacgtt ctctttccgt gtcaataaaa
    14521 aacagcaatt ttcaaatacg agcaaaaggc tcacatttgg aaattgctga gaggttattt
    14581 ttatctattt gtttttagct gagatcgttg atttttttat caaacatgaa cagcttctgg
    14641 atcgatcttt gttgtcccat ttccaatgtg tgcaacataa aattccggag catagccgac
    14701 aactttcatg tattcatcat agacattgtt tttgaaggca ggtatatttt cttctttgac
    14761 aagagcaatc gcacagccac caaatccagc tcctgtcatt cgtgcaccta agacaccttc
    14821 ttgtttttga gcagcatcta ctagtgtatc taattcgatc ccagttactt cataatcata
    14881 gcgaagagag tggtgagaat catttaacag ttgaccaaat gcttctaagt tcccagcttc
    14941 taattcagct tttgccttca aagtccgctg attttcagaa acggcatggc gagctctgcg
    15001 tatcaatgta tcatcgccga tttggtcaat agttgattca aattcttctt catctaagtc
    15061 tcctaaagaa gagataggca aagttttttg caaacgtgcc aaggcttctt cgcattcgct
    15121 acggcgttca ttgtattttg aatctgccaa ttcccgccgc ttattcgtat tcatgatgac
    15181 gattgcataa ccatctagtt tcactggaac catttcgtat ttcagcgtat ttgtatctaa
    15241 taagattgca tgatctagct caccgaagcc gatggcaaac tgatccatga tacctgaatt
    15301 gacaccgatg aattcatttt ctactttttt acctgtttgg actagttcca agcgatctgt
    15361 ttttaaatca aacagatctt ctaatacaac acctactaat aattctaatg aagcgctact
    15421 ggaaagtcct gcaccattag ggattgttcc ttccactaat aactcaaacc catgatcgat
    15481 tgagtgtcca gcttctttta atttaaggac cattcctttt acgtaatttg cccagtttgc
    15541 ttttttatca tattctagct catctaaagt aaaactaatg acaccgatat cgtcaaagtt
    15601 tgtggaataa actaatattt tattatcgtc tcgaggtgct gctacacctt gcgttccata
    15661 agtgatggaa gcggggaaga catggcctcc attgtaatct gtgtgttcac caatcaaatt
    15721 gatgcgtcct ggtgagaagt attgtgtagt ttttttaggt ccgaatgttt cggcaaattt
    15781 tgtgtttaag cttcttttga tttccatgat gagttattcc tttcttgttt tgattttgaa
    15841 ttctgtcact gtttcaaata ctgatccggc ttttaaatga atcgaaccaa atgctgagaa
    15901 gcgctctgca cctggagctg tttgagtctc aaatgtgatg ccaccgtgat gtgccagttt
    15961 tcggttgcgc atttctggtg tttctgtgcc gaaatttgca gtgaaaataa ccacactaga
    16021 agcatctgta gcaatatcta cttggattct tttatcgggg ctagtcaagc gagcggcttc
    16081 tttacccaag ccggtttctt ttaagaaaaa tggatgatcg attccgtcaa caagattttt
    16141 ttgatccaaa tcactagcaa aaacggacgc taatttttta ggtatttgaa aatcgaaagc
    16201 acttcctgca gcattttctt ttacccctat aggaatacta tctgttcgca aaggagcata
    16261 agcttcgcta ttgagccaaa gctcatgttg atcgattgac tgagaagcat ctcccgtcaa
    16321 gttgaagtaa acatgatttg tcggattgaa taaagtatct tggtcactgg tgccgcgaga
    16381 ggtcactcgc cagatattat cttttgtcaa agtatagcgg atttccacat ccattgtacc
    16441 tggaaaacca tgttctccgt cgggacttgt agtagtaaaa atgacagaag cttcattttc
    16501 gccattcaaa atgacataag accatttttt taattcaaat ccaggagcac caccatgcag
    16561 attatgtcca gtttttggat ctgtggctaa ttggtaagtt tttccattga gagaaaagtg
    16621 gccattttcg attctccctg cggtgcgacc gatagaagca ccgatatacg gatctttttc
    16681 gatatattct tcagcggtgt caaatcccaa aactaattct cgatcatttg attttaaact
    16741 gacgattcta gcacctaaat cagagataga aagtgctagc ttgtttttgt tctccaaggt
    16801 tatcaagtga taaccttggc caaaatcttt ttctgtaatc ttcattttca agatcctttc
    16861 ttaatgggaa ggaactactg catcgtgaag ttcatcttcc attgtatcag ctggagccaa
    16921 tttgttttcc aatttctcaa cgatttgtgc atgttttttc tctgtcaatg taatcttcca
    16981 agcaaaaata atagcggaga aaatcatcaa agcagcagga gcatagaatg cataagcttt
    17041 gaaagtcgtt acgccatgag cagtgatatc agcagcagta gcattaccag tcatcccaga
    17101 agcgatagcg acaaacccta cgatcccgtt agacaaagca ccagcgattt tatctagtaa
    17161 agggcgaatt gatagagtaa cagcttcgtt acggatacca tttttccatt gaccatattc
    17221 aacagagtct gtgatcgtca tcaaagcgga taagaaaatc aattgttgag ggaagtagaa
    17281 caatactagc ccgatgataa cgattggcaa acttgaacct gcgatcgtaa agaaaaagta
    17341 agaagaaatc atcattgcga tccctccaag gtaaacgtag cgacgagaga tgacgcgtgt
    17401 aagcattggg aatagtggaa cagctactaa accaagtaag gcagcaacta gaccaacgat
    17461 ccaaaattca gttggttggc caagtacata tttgaagaag tagaataata cggcagttgt
    17521 tgctacattg gcaatcgcat aagcgatata agcaagggca agccacatca actgatcatt
    17581 ttgagcaact gctttgaaca catctttgat cccagctttt tcattttgct gacggatcgc
    17641 agtatcgact tcttttgtgc ccaaggcagt gataatcgca gtaccgcctg aaataacagc
    17701 agcaatcaca ccgaaccaga accagcctga agcgccttca atatgtttat gagtaacaag
    17761 ataggtaaag aaagtaacga tagggacaac gactagagta gtaccatttg cacctagaga
    17821 agagccgaaa cgagcaaacg tagcaaattt ttcacgttcc tttgtttccg tactcaaagc
    17881 tggaatcatt gaccaaaaag cgatatcctt aaatgaataa aaactatcca ataagatgaa
    17941 aacgattgca aataatatga taaataaagt cgtattatga gtagctaagc caaagaaatt
    18001 ggtaaagatt gctaccaaga gtacggaact aacaacgccg ccgataacta accatggttt
    18061 gaatttaccg tattttgtac gagtattatc gatgatgcca ccaatcaaag gatcaaaaat
    18121 aatttcaact aagcggatac ctacaactaa gcttgtaact gtagcaatca tttttgcatt
    18181 cgttgcctta tctgttcctg cgaacatctg gcttgtcacg aataccataa aataagtgct
    18241 taatgtaaca tagaatgtgt cgtgtccaaa agcgcctaaa gcgtaggaca cacgttggat
    18301 cattttgctt ttcataatct gtattcctct cctgttcaat atataatact aagtaaaccg
    18361 gttacaacga ataacaaaga tcttttaatg acttaaactt aacaagaaat cgcttccttt
    18421 ttaatatatt tctgtgactt ttatttaact ttttgttgca ttatactaaa ggagtaagga
    18481 gggatagacg tggagcaatc gattttttta aaaaaggaac atcaacaagt agaaaaagaa
    18541 ttgtattttg atttttgtgg tttctctaaa acgatgccgt ttcattcttt tggtcctgct
    18601 attcgcaatg attacatcct gcatgtcgtg atggaaggca aaggatctta tcatgtgaaa
    18661 aatcaacaat tccaattgaa aaaaggtgat ctgttcttga ttcgtccagg agactcgacg
    18721 ttttacttat cagatggaga agatccgtgg atgtattgct ggctttcatt tggtgggagt
    18781 gctgcagaag aaatcattcg gcagtcgctt ttcagagaag accaatacac gatggtctct
    18841 tctgacatac aaaaatatat cgacattatt ttagaatgca tgaaagatac ggaagaaacc
    18901 ttggaaaatg aattacagtt aacagcatta acctaccgtt ttttatcagt ccttttaaaa
    18961 gatggcggaa aggtcagcgg tggtgtacaa aaggttcatt cctctttagc tgttgaaaca
    19021 gtcaaataca tcgaggcaca ttatgctgaa aaattgtctg ttgaggaaat cgcccagcat
    19081 ttagcggtca atcggagcca tttgtcgcga gtattcaaaa atcatatggg taccagtatc
    19141 aaggaatatt tgatcggggt acggatcaat cgaggggcgt ttcttctttc tctgacggat
    19201 gaatccgtgg aaagtattgc ctatcaagta gggttcaata gtctagtcgt atttagccga
    19261 atgttcaaaa agagtaccgg agaaacggct acgaactatc gtaaacgtat gaaaaacgaa
    19321 aattttaaga atattgcttt ggataccttg aaaaaacagt tggaaaaaca aaccgcagtt
    19381 tcttggacaa cctgattagt ctggttaaaa tgacaagcat cggcaaaaga aacttgtggc
    19441 ggttatgcta cactgtaaag cgaagactaa aaaggaggaa aagggatgcg tacacttatc
    19501 atcattagcc atccaacgat cgaagaatct ttaaatcagc aatttttcaa agaagcttct
    19561 gctggtttac cagctacttg gcatcatttg gaatcaagtt atccagacgg aaaaatagat
    19621 atagagactg aactacagct cttggcccag catgatcgga tcattttcca gtttccgttt
    19681 tactggtata gttctcctgc tcatttaaaa atttggcaag ataatgtctt ggaacgagca
    19741 gcacatgtat taaaagggaa agaactagga atcgtattga caacaggtgt ggcggaaaaa
    19801 gaataccaag ctggaggaaa agaagaatat acgatttccg aatttttgag gccgtatcag
    19861 cgaatcgcaa ataaattcca tatgacctat cttccgccat tcgttttagc acaatttatg
    19921 tatttatccc aggaaaaacg ttgggagaag ctaattgctt atcagcagta tctctcattg
    19981 gaaggcaaac catcgctgac tcagcggatt gactggttta ttcaaagagt acaggaaaat
    20041 cagaaaatgc aggaagaaga atctgaaaaa caagcatata tcgtagaagc actgactgag
    20101 gcaaaagagc agatcgaaga cttgaccttt acactgcaag aaatgaaagg aacttcatta
    20161 tgacaaatga ttggctgatc caacaattag atgaattaag cgaaaaatca gaatatcaag
    20221 accgtgcgct cttatatgaa ataaagaaac tgatggctga gatagacgaa cgaacaatgc
    20281 agctgcaagg agaaatcgac ggacaatctt ggaatcatct caactggtga aattttctta
    20341 taaataacaa agataaaaat gtgcacagcg acaattattt gctacaataa gaatatgaag
    20401 cgtttgataa cgctattata cataaaaatt ggtggtgaaa aaaatgtatg atgaaaatga
    20461 gtggggagaa aatgttcgga tgacccgaag aagacagcaa aaacaggcag ctcgtaagcg
    20521 gatgatcatg attggggcag cagttgccgt gtttttgatc atagcaggag gagttgcggg
    20581 tctatatttt catggaaaaa attcgtcaga agcgaaaagt acgaccataa cggaaacaac
    20641 gacaaagaaa acagagacga aacaaacaag tgagtcatca actaaaacaa aagagacaca
    20701 aacttctgaa gaaaaaacag caaatggttt gccagagcaa cttcaagcaa tcgtaaatga
    20761 ttattcgaaa aagatcgaag aaaagacgcc tgcattgatt gaagaatacc agacagaaat
    20821 tcagggaaat caagagggaa tagctggttt atcagcagtt gctaaccaaa aagcacgtga
    20881 gcttcaagca atctccgacg aagggatcag aaaattacgt gcagcgtatc aggcagcaga
    20941 aaataaagac ggtgtagact tagatacttt gatcaatcaa ttatcggcta attatacgaa
    21001 tcatgtcgct aagatttccg atatttattt gcagactagc gcctctcttc aagcagagtc
    21061 aacaagcaca caagacacaa catcttctga ttctgagaca gcagagtcgg tagaagcttc
    21121 tgaaatgcaa gctcgaacaa cacaagacac aacagattcc tctgaaacta ataccaacag
    21181 cgcgacttca caggctgcga caaccgtagt tttggaagga gaaggtccaa atcaaatagc
    21241 cgaacgaact ggcgtaccag tagaaacgat cttgtcgctg aatgggatga gcatggagaa
    21301 ttatttcctg actcccggtg agacgctaaa attgaattga taaaagcaat aaaaaagaac
    21361 gaagcttcca ctaaggtgaa gcttcgttct ttttttattt tccggttctt ttttcgcgta
    21421 caaagtaatg gatcgtcatg taaagcaaga aaacgagtcc aataatcaat gagattctcg
    21481 tttcaggatt gataaacatg aaaatcaata cgatagctaa aaaagcaagt gtcacataat
    21541 tcgtataagg agatagtggc attttaaaag gatgatcatg cattttatct gcgtgcttct
    21601 ttttgaagcg aatctcgctg atcaaaatca ctacccaagg aaccatacca ggcaaaatac
    21661 ttgagctgta tacgaaaacg aaaatatttt ctgactggtt gatgaacatt ggtagaagat
    21721 aatttaagat cagaccaatt aagattccac ctgagattgc tacgacagga taaaaaggcg
    21781 caccgtgacg agatagtttc agaaattttt tagacatctt tccatttatg gcaagtgtat
    21841 agaccatacg acttgcgctg aaaatccctg aattgcaacc tgataatgcc gctgtaatca
    21901 cgacaaaatt aatcagtcct gcagcaaatg taatgccgac tttagaaaaa gtttgtacaa
    21961 aaggtgaacc aatctcactc aattgattcc acggatagat actcacaatg ataaaaatag
    22021 caccaatata aaaaatcaag attcgaccga tagtggactg gacagcttca atgatcgtct
    22081 ttttaggatt ctctgcttca ccagcagtca ttccgatcag ttcgattcct tgataggaag
    22141 caacaacgat cgataatgca aagaaaaatc ctttgacgcc tccagtgaag aatccaccat
    22201 ttttccaaag atttgaaatc cctactgcct gaccatgatt accaaatcca aataagatta
    22261 ccccaagacc tgcaatgatc atcaaaatga tcgttatgac tttgatgatc gaaaaccaaa
    22321 attctaattc gccaaacgcc ttgacagaaa taagatttgc cagcataaga aacaagacga
    22381 caatgattcc gggaataatt gccggcaaat caggccacca ataattcata taagatccta
    22441 cagcaatcac ttcacttatt cctacgacaa tatattgaaa aatattactc caagcggtca
    22501 agtagccagc cacaggatgg atgtactcgc tcgcgtaatt tgcaaaagaa ccagtcgaag
    22561 gatcaacgta aagcatttcg cctaaagcac gcataatcaa atacaaaaag aatcctgcaa
    22621 tcgcataggc tcccatcact gagggccctg tccaacgtat ggttgaggag gcacccataa
    22681 acagaccgac accgatcgtt ccacctagtg cgatcatttg gatatgacgg gcactaagac
    22741 ttcgagttaa cttttcttct tccatacaaa aactcctttc gttgttgagt caacaagaaa
    22801 aaataatcaa acgtttcaac acatgttttt cattattagg ttagccttat tgaactcttg
    22861 atgtgattct acagaaaatt ttcataaaat gcgaggaaaa ttcgaaaaaa actttttcat
    22921 cattctactt gaaaatgctt tccattttag ttaaactata tttaaataaa aagttaggta
    22981 aacctaaaaa ggagtgtaag atttggaacg tacggccatt gtaattcaag acctttcagc
    23041 cgcttatcaa gggaaaactg ttttgaaaac tatcaacttg acgataaatc cacaaaaaat
    23101 taccggtatt atcggaccaa acggtgcagg aaaatcaaca tttatgaaat ctttgctaga
    23161 gttgatacca gctactactg gtaaagtcac cttttctgga cagtcggtaa actcagtccg
    23221 taaaaaaata gcctacgtgg aacagcgaag tgaattggat ctttcctttc caattgatgt
    23281 attaggcgtt gtacttttag gaacatatcc atctttacga attggacaaa gacctgggaa
    23341 aaaagaaaaa gaacgtgcaa gacaagcttt gaaaaaagta gggatggaag aatatgccaa
    23401 aagacagatc agcgaactat cgggtggaca gcttcagaga gtttttattg caagagctct
    23461 agcccaagga gcagaatgga tctttttaga tgaaccattc gtagggattg atgcgttaag
    23521 tgaacgaaag atctttgaca tcttgcagga attgaagaat tcaggaaaaa cgattttgat
    23581 cgtccatcat gatcttcata aagtagaaga atatttcgat gaggttattc ttttaaataa
    23641 acagctgatc gcttccggtc cagtacaaga agtctttaca tcgaagaacc ttcaattggc
    23701 ctatggtgag atcatcagac atttagtaaa aggaggagag aaaaaatgat ccaatccttt
    23761 attgatggat taatgaatta tcaattcctg caatacgctt tggtcacttc catgcttgta
    23821 ggacttgctt ctggagtcat cggttctttt attattttac gagggatgtc tttgatggga
    23881 gacgctatct ctcacgcagt tcttccaggt gtagccattt cttatatgtt tggttttagt
    23941 tacatctttg gagccactgc ttttgggatg ctaacagcag cagtgattgg tttcgtgact
    24001 cagcggagcc gattgaaaaa tgatacagcg attggaattg tctttagctc cttttttgca
    24061 ttagggatta tcttgatttc atatgcccag agtgcgacag atttgtatca tattttattt
    24121 gggaatgtct tagctgttag ggaaagcgat ttgttgctga cagcactcgt tagtggaatc
    24181 gtcttgatat ttgtcttttt cttttataaa gaattgaaga tcacatcatt cgatccgaca
    24241 atggcaaaag cttatgggct gaacacatcg ctgatccatt atcttttgat gttctttttg
    24301 acattagtgg ctgtagtcag tttacagaca gtaggaacaa tcttggtgat tgccatgttg
    24361 atcacaccag ccgccacggc ttacttgcta acgaaccatt tactgaaaat gatcattaca
    24421 gctgcaggaa tcggtatgct aagtgcagtt gtcggtgtgt ttttcagtta tagttacaat
    24481 tggccatcag gagctacgat cgtgttagca tgtaccgcat tttttatcct tgctttttta
    24541 ttttctccaa caaaaggaat tttatttcag aaaggaagca gatagatgaa aacaaaaaaa
    24601 tcactctttt taatcttggc agttagtttc ttggtattag ccggttgcgg aaagcaggct
    24661 tctgaccaag cggatgaagg aagtaaagaa aagttgtcag tcgtggctac caattcgatc
    24721 ttggcggaca tggcaaaaga ggtcggaaca gatcaaatag atatccacag tatcgtacca
    24781 gtcggaacag atccgcatga atatgaagta ctaccagaag acatcaaaaa ggcaagcgat
    24841 gcagatgtta ttttatacaa cggtttgaat cttgaaacag gtaacagctg gttcgataac
    24901 ttgatggaaa cggctaaaaa agaagaagga aaagattatt ttgcagttag caaaaatgta
    24961 gaacctcttt atttaactag cggtgaagaa catacaaaag cagatcccca tgcttggcta
    25021 gacctatcta acggaataaa atatgtggag gaaatcgcac gtatattctc tgaaaaagat
    25081 gcagaaaatg cgacactcta taaaaaaaat gcagaagcat atgtggaaaa actaaaagaa
    25141 ttagatacac aagcgaagga aagttttgct tctatcgaag agaacaaaaa attattagta
    25201 acaagtgaag gggcattcaa gtatttttca cgagcatatg atttgccagc agcttatata
    25261 tgggagatca atacagaaag tcaaggtacg cctgatcaaa tgaaagcgat cattgatcag
    25321 ataagagcaa aagaagtacc ggttttattc gtggaaacca gtgtagactc aagaagcatg
    25381 gaacgggtag caaaagaaac gggtttgaaa atctatgata aactgttcac tgattccata
    25441 gcaaaagaag gagaacaagg agattcttac tatcagatga tgaaatggaa tattgaaacg
    25501 atccatgaag gtttgtcaca aacaaaagaa agctgaaaag tgcaaggtct agcttgagga
    25561 gcagaccttg cattttttat aagagatatg aaaaaaaatt atgctgtttt tcgtcgtaca
    25621 gatacctttt ttgaagaaat tccgttatag ttagagtaag gaaggaaggt gtggctatga
    25681 attttacacg taaagataaa tatacgatta aagaagaagt ctttcgattg atcagccagc
    25741 aggaaaatac cgacaaggat caagaccttc aatttcttga agcagaatta gctaaattat
    25801 tcatagcaaa tcaaaatgag acaacagaac cagatgaaga gctgtacata ggcaaatggt
    25861 tgtttgatga atttcagcct ttagatgaaa ataccggtat cggttatttt gtgttccttt
    25921 ctccagtcgg cttcacacct ggcgtattag ttaaacaaaa cgacgaaata accgtcaaag
    25981 catggcctgc attattttca gtcatcaaag cagaaggagt aatcaaaaag atccagtcgg
    26041 cctattataa aagtcaattt attgccaaca gcaaattaat gaatatgttt tataatcgtc
    26101 tagtagaaat tgctaggcct gggaaaatcc cgcaaacatt cacgtacaca cagcaaaaaa
    26161 atctctatga agaagtattg tattcccgcg atctgtctga gttttcgcca tgggaagagg
    26221 taaggctcca tgaactgtta agtacaaaac cagtttcatt gaattttttt aatgcattag
    26281 ataacaaaag aaaattaatt tcaacaaatt attgggaagt atttgctgca agaaaaaaat
    26341 ggatggaaga aaagaagatt gccgatcagc agatccagtt tgtccagctg aaaaaagaaa
    26401 aactatatta tgggttatac agccgttaac agcaagcgag gaagaccatg acattaaaag
    26461 aagaaatcat acaagaaagc aaacgattag gaattgacaa aatcgggttc accacggcgg
    26521 aaccttttga ttcattaaaa gaatcgttgg aagaacaaaa agcagctggc catacttctg
    26581 gctttgaaca tccaaatatc gatgagcgtc tttatccaga aatgacattt gatcagccga
    26641 aatcgatcat ttccattgca cttgcgtatc ctactaggat ccatgaagaa gtgcctaggg
    26701 atgaaaaacg cgggcagttt gctcgtgctt cttgggggat cgattaccat gatatactca
    26761 gagaccgttt gaaccgattg atcgaattca tccaaacaag agcagaaaaa tggcaaaaag
    26821 aagaggaatg gcgtctagct ccgcaagtag atactggaga actgatcgat gtcgctgtag
    26881 cacagcgagc tggtttagga tttattggac gaaacggatt gttgatcact gaagagttcg
    26941 gttcatttgt ctatcttggt gagatcgtta ctaatattgt atttgagcct gataaaccag
    27001 gagaatttgg ttgcggtgac tgtatgcgct gcgtgactgc ttgtccgaca aaagcattgc
    27061 ttggtgacgg aagaatgaat gcccagcgat gtttgtctta tcaaactcag acaaaaggga
    27121 tgatgccgga agaatatcgt aaaaaaatgc gaaatgtcat ttatggatgt gatatctgcc
    27181 agttagtctg cccttacaat caaggaaaag attttcattt tcatgaagag atggaaccaa
    27241 aagtagacga aatatatcca aaattaaagc caatgctttc gatgtctaat aaagacttca
    27301 aacagcaatt tgggcattta gctggttcat ggcgtgggaa gaaacctttg cagagaaacg
    27361 cattgattgc tttagctaat ctaggtgatc gaacggcatt gcctgagatt tcagaatgtt
    27421 taacagatgt ccgccctgtc atcagaggaa cagcagcttg ggctattgga cgtctaggaa
    27481 caaaagaacc ggaaaaatgg cttgatgtat tagatgaaat attagctaaa gaaacagaag
    27541 aagtcgttat aaacgaattg gaacatgccc agaaattatt gcggagaaag ttaaaataaa
    27601 aaaatagtta acattattca aagtttttgt ccagta
//
LOCUS       DADVXM010000031        26276 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.032, whole genome shotgun sequence.
ACCESSION   DADVXM010000031 DADVXM010000000
VERSION     DADVXM010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.032"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            100..1104
                     /locus_tag="KB927_001394"
     CDS             100..1104
                     /locus_tag="KB927_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840319.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            1105..2049
                     /locus_tag="KB927_001395"
     CDS             1105..2049
                     /locus_tag="KB927_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840320.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            2049..3011
                     /locus_tag="KB927_001396"
     CDS             2049..3011
                     /locus_tag="KB927_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6840321.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            3038..3952
                     /locus_tag="KB927_001397"
     CDS             3038..3952
                     /locus_tag="KB927_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6840322.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            3978..5759
                     /locus_tag="KB927_001398"
     CDS             3978..5759
                     /locus_tag="KB927_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6840323.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            6107..6793
                     /locus_tag="KB927_001399"
     CDS             6107..6793
                     /locus_tag="KB927_001399"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBB6840324.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            6813..10394
                     /gene="smc"
                     /locus_tag="KB927_001400"
     CDS             6813..10394
                     /gene="smc"
                     /locus_tag="KB927_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBB6840325.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            10403..11212
                     /locus_tag="KB927_001401"
     CDS             10403..11212
                     /locus_tag="KB927_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6840326.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            11223..12221
                     /gene="ftsY"
                     /locus_tag="KB927_001402"
     CDS             11223..12221
                     /gene="ftsY"
                     /locus_tag="KB927_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBB6840327.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            12408..14675
                     /gene="gshAB"
                     /locus_tag="KB927_001403"
     CDS             12408..14675
                     /gene="gshAB"
                     /locus_tag="KB927_001403"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBB6840328.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(14764..15216)
                     /locus_tag="KB927_001404"
     CDS             complement(14764..15216)
                     /locus_tag="KB927_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBB6840329.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            15366..16316
                     /locus_tag="KB927_001405"
     CDS             15366..16316
                     /locus_tag="KB927_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBB6840330.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            16309..17268
                     /locus_tag="KB927_001406"
     CDS             16309..17268
                     /locus_tag="KB927_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBB6840331.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            17265..18020
                     /locus_tag="KB927_001407"
     CDS             17265..18020
                     /locus_tag="KB927_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6840332.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            18043..18996
                     /locus_tag="KB927_001408"
     CDS             18043..18996
                     /locus_tag="KB927_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6840333.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(19640..19936)
                     /locus_tag="KB927_001409"
     CDS             complement(19640..19936)
                     /locus_tag="KB927_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBB6840334.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            20291..20647
                     /locus_tag="KB927_001410"
     CDS             20291..20647
                     /locus_tag="KB927_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6840335.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            20657..21556
                     /locus_tag="KB927_001411"
     CDS             20657..21556
                     /locus_tag="KB927_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBB6840336.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            22073..22804
                     /locus_tag="KB927_001412"
     CDS             22073..22804
                     /locus_tag="KB927_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6840337.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            22949..24976
                     /locus_tag="KB927_001413"
     CDS             22949..24976
                     /locus_tag="KB927_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBB6840338.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            25084..26181
                     /locus_tag="KB927_001414"
     CDS             25084..26181
                     /locus_tag="KB927_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBB6840339.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
BASE COUNT         8777 a         4572 c         5569 g         7358 t
ORIGIN      
        1 aaagataaga ataacctttg ttataaaacg atttattctg tgtaatgtcc ttttttatta
       61 agaaaaactt ccatttagga agcagagagg ggtattcgat tgtccgataa ccaattatta
      121 gaagttcaga acctacatac aggattccga ctcaaagatg actattacga tgcagtagat
      181 gacgtttcat ttactttaga caaaaacgag attttagcaa tcgttgggga atctgggtgc
      241 gggaaaagta ccttggctac tacgattatg ggattacttg atcctaataa cacaaaaatt
      301 acaggtgaga ttttatataa cgatctgaat ttaatcgacc tgaacgaaac gctctataat
      361 aaaatccgcg gaaatgatat cggaatgatt ttccaagatc cgttgtctgc attaaatcct
      421 ctcatgagaa tcgaagacca gatcaaagaa ggactttcct atcacacaaa gatgaatgca
      481 gaacagcgtc aagctcgtgc actagaattg ctagaacaag tagggattcc taatcctgcg
      541 agagttggac gccaatatcc ccatgaacta tcaggcggta tgagacaacg tgtcatcatc
      601 gcaatcgcaa tcgcctgcaa acctccaatc gtcattgcag atgaaccgac gacagcccta
      661 gatgtaacca tccaagcaca gattcttgat ttactgaaag accttcagga agaaacaaaa
      721 acagggatca tcttgatcac tcatgactta ggagtcgtag cagaaatggc tgatcgagtg
      781 gcagtgatgt atggcggaca gttcgttgaa gtagcaggtg taaaagaact gtttgatcat
      841 cctaagcatc cttatacacg ctctttactg aactctatac cacaagaagg aaatcatgat
      901 gcagaactcc atgtgatcga aggtgtcgtt ccttctctga aaaacatgcc tcgtaaaggt
      961 tgtcggtttg caccacgtat tccatggata ccagcaagcg atcatgaaga agagcctatc
     1021 cttcatgaag tcgcaccgaa ccacttggta cgttgctcct gctataagca tttccacttt
     1081 agagacgaaa aaggagaggt gtagatgaca gaattaatca caatcaaaga cctgaaagtt
     1141 cattacccta ttcgcagtgg attcttcaat cgagtaacgg atcatgtata tgctgtagat
     1201 ggtgtggatt ttattatcga aaaaggaaag acatatggtt tagtgggaga gtctggctct
     1261 ggaaaatcta ctacgggaaa agccgttgtg ggattagaaa aggtaacagc cggacaaatc
     1321 atgtatgaag gaaaagatgt aacgaagcga agcaaccgca aaaaaatggg ttataacaag
     1381 gatgtgcaga tgatcttcca agattcaatg tccagtttga atcctaaaaa gcgagtgttg
     1441 gatatcattg ctgaacccat ccgaaatttt gaacggttaa gcgatcaaga agaaaagaaa
     1501 aaggtaaaag gactgctaga tatcgttggg atgccggaag atgcgctata taaatatcct
     1561 catgaatttt caggcggaca acgtcaacgt ctaggagtag cccgtgctgt tgctaccaat
     1621 ccaaaactga tcgtagccga tgaacctgta tctgctctgg atctatctgt tcaagcgcaa
     1681 gtattgaatt tcatgaaacg aatccagcaa gaatacggcc tcagctattt attcatttca
     1741 catgatttag gtgtagtaaa acacatgtgc gacaatatcg caattatgta caaaggtcga
     1801 tttgtagaaa tcggtacaag agaagacatt tataatgacc cgcgacatat ctatacgaaa
     1861 cgtctgcttt cagctattcc gcaaatcgat gtagaaaata gggaaagcca caaagaaaat
     1921 cgacgaagag tagaacaaga gtatatccaa aaccaaaaag aatactatga tgcgactggt
     1981 cgagtctacg atttgcgtac gatcacaact acacacaaag tggcgttgaa agatggaggt
     2041 gcaagctaat gtggaaaacg attctgcgac gtgttttatt gatgatcccg caagttatta
     2101 ttttaagtgt tctgatcttc ttattagccc aagcgatgcc gggggatcca tttaccggtt
     2161 tgatcaatcc aaatcaggat ccggcagtga tcgaacagat gcgacaagca gctggcttga
     2221 atgacccatg gtatgtccag tacttccgtt ggatcggaaa tgctttgcaa ggcgattttg
     2281 gtcaaagttt cttatacaaa cgctctgttg ctgacttgat cggcgaacgg atcatcaaca
     2341 ctttatatct atcgatcttg acagttgtcc ttacttattt gattgctgtg cctctgggga
     2401 tgcttgctgg ccggtatcaa aattcaatct tggataagat tgtcgtaatc tacaacttct
     2461 ttagttttgc tgttccttta tttatcttcg gcttgatcat gctatttgtt tttggttatc
     2521 gtttaggctg gttcccaaca agtggatcac aaacactagg tttgcaaggt ggatttatca
     2581 ctcaatggat agaccgtttg aaatatattc tgttaccatc aattacccaa gcatttttgg
     2641 cgactgccgt cacaatccaa tatctgcgaa gtgaagtaat cgattcgaaa tcgctcgatt
     2701 ttgtcagaac agcccgttcc aaaggggtac cgacgaataa agtattcagt cgacatattt
     2761 tccgaaatgc agcgttgccg atggcttctc aaatggggta tgaaatcact tcgttgattg
     2821 ctggttctgt agttatcgaa aagatttttg gttatccggg agtcggaaaa ctatttattg
     2881 attccatcgg ccaacgggac tataccgtga tcacatcctt agtattgatt ttaggaatcg
     2941 cgacgctagt ggggacatta ctttcagata tcatcatgag tatcgttgac ccgcgtattc
     3001 ggattcaata aaaccaatca gaaaggagaa tggatcgatg agtgaaaaaa acaatacagc
     3061 agttcaagaa agtattcctc ctatggggat acgaatgatt gctcgagaat ttaaaaaaga
     3121 taaaattgct attttttcat taggtttgct agtggtttta ttattagtga tctttatcgg
     3181 tgcgatgctg accgatcaag acaaagtgat gtatgttagt atcttcgaca aatacgctgc
     3241 accaggaaca gtttcgacac aaggacaaaa gttcattctg ggagcagatg aaggcggacg
     3301 tgatgtatta ggacaattga tcataggtgc tagaaactct gttacgatcg gatttgcgat
     3361 cacgatcctt acttcgatca tcggggttgg attagggatc atctctggct actacggagg
     3421 gatcattgac aacatcttga tgcggatcgt tgattttatc atgattctac cgatcatgct
     3481 gatcattatc gtcttcgtat cgattatttc cagatacaat gtctggtcct ttatattcat
     3541 catgagtgca ttttattggg tagctaaagc ccgattattc cgaagcaaga cattatctga
     3601 agcaagaaga gattatgtca gtgcctcaaa aacaatggga accaatgatt ttaaaatcat
     3661 gttccgcgaa atcatgccga atctaagttc attaatcatt actaatttga cgatgaactt
     3721 tgcggcaaac atcggtatcg agacaacttt gactttctta ggtttcggct tgccggcaaa
     3781 tgtacctagt ttaggtacat tgatcggtta tgcaagtaac ggagaagtct tagtgaatcg
     3841 gcaatggatc tggttacccg catcaatcct tattttagtt ttgatgttga gtatcaatta
     3901 tgttggacaa gcattcaagc gttctgcaga tgcgcgccaa cggttaggct agtatagaag
     3961 cgaaggggga aataggaatg aagaaaacga tttttggatt tgcagcgctg atgtctgctg
     4021 tcgttcttgc agcatgcggg ggcggaggta cagatacctc tggaaacaac tctggaggca
     4081 acggcaataa caaagaggaa ttaacttttc caattgcaac aaaaaataat gatgatgcaa
     4141 tcgaagacgg cgaattagaa gctgcggtcg caacggacag tcagtttaaa ggattgttcc
     4201 agtgggagtt ttaccaagat tcatatgatg cagcttttat ggctccttct catgaaccgc
     4261 tatttgcaaa cgatgacgat ttcagaatca cagacgacgg agctgcaacg cttgatctag
     4321 atgaagatac gaaaaaagcg acaatcaaag taaaagacaa cgtcaaatgg tcagatggtg
     4381 aagatgtaac ggcggacgat gtgattttcc cttacgaaat cattgggaat aaagattaca
     4441 ctggtatccg ttatgacgac actttccgta acatcgtagg tatggaagaa tatcatgatg
     4501 gaagtgccga cacaatctcc ggaatcaaaa aaatagacga caaaacagtt gaaatcgaat
     4561 ataaagaagt aaacccaagc atgcttcaat cgggtggtgg tatctggtca tatgcagcac
     4621 caaaacatac gttagaaggt gtagcaatca aagatatgga atcaagcgat caagtacgta
     4681 aaaatccagt gacttttggc ccttattaca tgagtaatat cgttgcagga gaatcagtag
     4741 aatacttgcc aaacgagcac tactggaatg gtacgcctaa attgaaaaag atcacgatga
     4801 aatctgtacc gatggcaagt gcaactgaag cattgaactc taaattatat gatatgattt
     4861 tccaaatgcc aacagatact tacgatacct ataaagaaat tgctggctat acaaacttag
     4921 gccgtgaaca aacttcttat acttatctag gattcaagtt aggtaaatgg aatgcagata
     4981 caaagagtgt ggaatacaat ccagattcaa aaatggctga taaatcatta cgtcaagcaa
     5041 tgggctatgc attagataat aatgcagtag gtgaacgttt ctatgcaggt ttgagaagca
     5101 atgcgacttc attgattcct ccagtattcc agtcatacca tgatgatgag atgaaaggat
     5161 tcacacaaga tctagacaaa gcgaaaaaac tattagatga tgctggctac aaagatgtgg
     5221 atgacgatgg tttaagagaa gacaaagatg gaaataaact aacaatcaac tttgcttcga
     5281 tgtccggtgg ggaaacagcg caaccattgg cagattacta tatccaacaa tggaaagaaa
     5341 ttggtttgga tgtccaatac acaacaggtc gtctgatcga attcaattct ttctatgata
     5401 aattagaaaa cgatgatcct gaaattgatg tttaccaagc tgcttggaat acaggaactg
     5461 atccaaatcc aagtggacta tggggaccaa atgctgcgtt caactacact cgttatgaat
     5521 cagaagaaaa tacaaaattg atcaacgata tcagttcaag caaagcattt gatgaagagt
     5581 accaaaaaga agcatatcaa aaatggcaac aatatgcatt tgaagaagca tttgcgattc
     5641 caacgttgtt ccgtaatgaa gtattgccag tcaacgaccg tgtcaaagac tgggattggt
     5701 cttatgatgt accaaaccca tgggcaaatg tttctgttac agcagattca cgttcataat
     5761 cactaaaaat gaccgaaaaa gggcgatgtc ctttttcggt tttttgatat ttttctgttt
     5821 atttctctaa tattcaggtc aaggcgctga tttcatgact tctccaataa acggtgttca
     5881 aagtccagtt tctcggtatt aagtcaaatt tatgcaaaaa tatggaaagc cattttcaca
     5941 aaattttttc ttcatactcg aaactaaacg aatttttcac aacttctcgt caatcactag
     6001 gattattaaa gctttactta ccttttgacc gaaccatttc aaatttgaca aaaaaccagt
     6061 ataataagga agtatcgaaa aaatatccat aaaaggaatg tggaaaatgg acaaccagct
     6121 gacaaaagaa ctaaaagaaa actataacat cgtttttcac gatctaaatt tgcttgaaca
     6181 agcttttacc cattcatcct atgtgaatga gcatcgcaat ctgcaattat cggataatga
     6241 gcgacttgaa tttttaggag atgccgtttt agaactgatg gtttctcagt atttattccg
     6301 tttatatcct catttgccag aaggaaaatt gacaaaaaca cgagctgcga tcgttcgcga
     6361 agacagcttg tcgaaatttg ccaaagaatg tcactttgat caatatgttt tgttgggcaa
     6421 gggagaagag aattcaggag gacgtacgcg accagcattg ctttgcgacc tattcgaagc
     6481 ttttttaggc gcgttatatc ttgaccaggg attcgacacg acccatgcat tcatcgaaaa
     6541 agtgattttt cctaaagtca aagcaggtgc tttttcacat gagatggatc ataaaacaaa
     6601 actacaagaa gtcttgcaaa aatcaggtga tgtatcaatc gaataccgat tgatcaatga
     6661 agaaggtcca gctcatgaac gagtattttg gatcgaagtt tatgtagatg atcaattgat
     6721 tggcactgga caagggaaat cgaaaaaatt agcagaacaa gctgcggcgg aaaatgcatt
     6781 ggcagcactg taaaagtaag tgagggaaag ctttgtattt gaaacgaatt gaaatagccg
     6841 gttttaaatc atttgcagac aagacagtca ttgattttga aaatagcgtc acagcagtgg
     6901 ttggaccaaa tggcagcgga aaaagcaata ttacagaggc tatccgctgg gtattaggag
     6961 aacaatctgc taaaagtctg cgaggcggaa aaatgccgga tatcatcttt gccggttccg
     7021 atacccgtaa gcagctgaat attgcagaag tcacagtgat tttagacaat agtgatcatt
     7081 atctgccatt ggagtacaat gagatcagtg taacccgccg ttatcgacgg actggggaaa
     7141 gcgagttttt catcaataaa caaagctgca gattaaaaga tatccaagaa ttgttcttag
     7201 attctggatt aggaaaagaa tcgttctcaa tcatttctca aggaaaagta gaagcgattt
     7261 tcagtagtaa accggaagac cgtcgtggga tctttgaaga agcagctggt gtcttgaaat
     7321 acaagcagcg gaaaaagaaa gcagaacaga agctttttga aacagaagac aacctcagcc
     7381 gcgtccaaga catcatccac gaattggaag aacagttaac tcctttggcc gcccagagtg
     7441 aggcagcaaa ggagttttta cggctaaaag aaacactgac tcaaaccgat gtctctttga
     7501 tggttgctga aatcaagaca gcaaaaaaag attgggacaa caaacaagca cagcttgcga
     7561 aattcaatct agaattaggc aaactatctg agtcgatcca agaacaagaa tccattttgg
     7621 cgaagcagcg taaagaaaat gcgcaagccg atcgtctgat cgaaaaaaat cagcaagtat
     7681 tattagatct ttcggaaaaa ctgaagcaga cagaaggaca aaaagatgtt ttgcaggagc
     7741 ggacaaagca tacacaaaaa agctcgcaag aatatcaaac ttcattagca gaagcacaaa
     7801 aaaaggttaa acattttgaa aagcttcaag aaagcttgat gaaagcagca gcagaaaaag
     7861 aaacagagat ccaaaaagct gaagcaaatc tcataaaaac acagcaagaa ttagaaaaat
     7921 accaaaaatc aacgaaagaa ttattggcag aattaagaga tcaatatgtt gatttgatgc
     7981 aagaacaagc agctgtagga aacgaactga agtatctaga acgtcaatat atacaagaaa
     8041 cagcaaaaag caagcagacg ttagccaagc aatcggaagt agaagcatca gtagaccgat
     8101 tgatcttaca aaaagaagaa ttgacacaaa agcaggcgca gctaaaatca tctttaactg
     8161 aaacaaaaga gaagttagaa atgatccaac aaaacgggaa aaagttccaa gaagcattag
     8221 caaaagaaca gcctaaaatg tatcaattaa tgaatcaagt ccagcagcta cgtgctcgta
     8281 agaaaagcct tcaagaaatc caagaaaact attttggttt ttaccaaggg gttcgattgg
     8341 tcttgcagca taaacagcag ctttcgggta ttgtcggagc agtggctgaa ctgatcgatg
     8401 ttcctgcaga tttcacgtta gctatcgaaa cagctttagg tggggcagcc cagcatgtca
     8461 tcgttgaaaa tgaaaaagat gctcggcaag ccatcacgta tttgaaacag caaagaggag
     8521 gaagagcaac attccttcca ctgacgacaa tcaaaccaag acaattaccg gctcatatat
     8581 tgacacaagc agcagctgta gaagggttta tagggattgc cagtgaacaa gtcagttatc
     8641 ccgatcaaat ccaaactgtg gttcaaaacc tgctaggaac gatcctttta gccaaagact
     8701 taactagtgc caatgcaatc gcgcaaacga tccgctatca atatcgagtg gtttccttag
     8761 aaggtgatgt gatgaatgcc ggaggatcca tgacaggtgg agcgaataaa cgaggaaacc
     8821 aaggcagttt gtttgtacaa aatcaagaat tgaaacagtt gactagtgaa tttgaagaag
     8881 cagataaaca actccaagca caagaaaaaa aagttcagga gctgcaacaa gaaacagctc
     8941 gtttagccga agaacaagaa gttttgcgta cacgaggcga acaattacgt tttgaagaac
     9001 aagaagcgac aaatcagcta caaaacatca taaatgaact tgaacgtttt gaaaaagaaa
     9061 agcaaatctc aacttttgag acacgtgaac tgcagcagtt tatcgaagat tacgaaaagc
     9121 aaacgaacga attgaaagac aaacaaacag atcttgaatc gcaacgacaa aaaatcgacg
     9181 aagaaatcaa atcgttaagt caagaaagcg accagatgga agccagaaga gcacaagtac
     9241 aaagtcaaaa agcacaagaa caagcagatc ttgctgtctt gaaagagcag tttaatcatc
     9301 tgcagatcca gctccgcggt gcccgagtcc aaaaagcaga ggcaaccgaa cgtcaagaag
     9361 cgatagaaaa gcagttggcg acattgacag cagacttttc tgatcatgaa gtcacagaag
     9421 aaagtttgga aaaacaaatt aacgaattat ctgctcagcg agaaacatta aaagccgagt
     9481 tggcaaaagc caaagagcag cgagatagaa ggcaaaagga gatcgataag cttgaagcag
     9541 tcttggcaga gcgtaatcgt gagcaaaaag cacgactgtc ggaacaatcc aaattagaag
     9601 tccaaaaaga ccgagctgaa atgattttag ataatcattt gacctatctg cagtcagaat
     9661 atcagctgac atttgagaaa gcttcccaag actatcaaga aacaaccgat atcgaagaca
     9721 gtagaacaaa ggtttcatcc ttaaaagaac agattgaaaa actgggacca gtaaacttaa
     9781 attcaatcga acaatacgaa caagtcagtg aaagacatac attcttagca acacagcgag
     9841 atgatctgtt agcagcgaaa aaccaattgt ttgaaacgat ggatgagatg gatgatgaag
     9901 tgcggacaag attcaaagaa gtatttgaag ctatccgtca agaattcaaa attgtctttc
     9961 caaatatgtt tggcggcggt aaagctgaat tagtactgac ggaaccaact gatttgctga
    10021 aaacaggtat tgagattgaa gtacaacctc ctggcaaaaa actgcaaagt ctaagtttgc
    10081 tttctggagg agaacgagca cttacagcca tcgcgttgct cttttccatt atccgtgtct
    10141 gtcctgttcc gttttgtatc ttagatgagg tagaagcagc gttagatgaa gccaacgtga
    10201 aacgttttgg tcgttacttg agcgatttcc aagatgacac acaatttatc gtagtcacac
    10261 accgcaaagg aacgatggtc gcagcagatg tactgtacgg agtgacgatg caggaatccg
    10321 gtgtatcaaa aatcgtttct gtacggatgg aagatatcaa tgaagaggcg aaaatcaacg
    10381 aaacgaaagt gtaggaacga aaatgatcaa attagtagca atcgatttgg acggtacatt
    10441 attaaatgaa caaaagctga tttcagatga gaataaacaa gcattagcac aagcaaaaca
    10501 gcaaggggtc aagatcgttc tatgtacagg acgcccctta gctgcgatgg cgcattatct
    10561 gcaagaatta ggactggtag atgaaggtga ctacagcatc actttcaacg gcggtttggt
    10621 acaaaaaaat gatactggtg aaatcatgga aaagaaagtg atggaagtat cagatatcca
    10681 acgcttatac aaactggctc agcaattgga tctgccacta gatgttttgt ctgacaatgt
    10741 ggttttacag ctgcctagtg ccccaaggaa gcaatccttg tacaatgtgt tgaataagct
    10801 gctgcaattc caaccagcgg atataagcga tattacagat gaatttgtgc ttaataaggc
    10861 agtaatcgct tatgaccaag aagaattaga tcctaaaatc aaagaaatac cagcagaatt
    10921 ccatgaaatg tatgagatca tcaaaacaag aagtatgctt ttggaattta tgccaaaagg
    10981 tgttacaaaa gcttatggta tttctttatt ggcaaaagat cttggtttga aacaagaaga
    11041 aatcatggcg atcggtgatg aggaaaatga tttaccgatg atccaatatg ctggactagg
    11101 cgtagcgatg gagaatgctg tgcctttcgt caaagaagca gcagatttcg tgacagccag
    11161 caatgaagaa aatggcgtag ccaaagtgat ccaaaaattt gtattagagt agggggagtc
    11221 aaatgggatt ttttgataaa atcaagcgtg cttttactgg cgaagagaaa acagaagaag
    11281 ttgaagtaca ggagaagtac gacaagggtt tagaaaagac gcgtaaaaca tttggtgaac
    11341 ggatgaatga gttgtttgcc aattttcgaa cagtcgatga agactttttt gaagaattag
    11401 aagaaacact tatcggtgca gatgtaggtt ttgaaacagc gatacgaatt accgaagcat
    11461 tacgtcaaga agtgaaactc agaaatgcga aaaaatcggc agaagtccaa aatgcgatca
    11521 tcgagaaact tgtggatctc tatgaagcgg aaggaatcaa tgaagtaaat gaactaaata
    11581 tccaagaaga cggactaaca gttattttgt ttgtcggtgt taatggtgta gggaaaacaa
    11641 caagtattgg taaacttgcc catcagttca aaaacgaagg taaaaaagta ttgatggcag
    11701 cagcagatac cttccgcgct ggagcaatcg accagttagt tgtctggggc gaacgcgctg
    11761 gtgttgaagt tgttcgtggc aatgcaggag gcgatccagc agctgtcgta ttcgatgctt
    11821 tggaaagagc aaagacagag caggcagatg ttttactagt tgatactgca ggccgactgc
    11881 aaaataaagt gaacttgatg aacgaattag aaaaaataaa acgagtaatc cagcgggaat
    11941 taccagaagc accccaagaa acacttcttg tattagatgc aaccactggt caaaacgcga
    12001 tggttcaagc aaaacaattc aaagaaacaa cagatgtgac cggtcttgtt ttgacaaaat
    12061 tagatggtac agcaaagggc ggtatcgtac ttgctatccg taatgaattg catttaccag
    12121 tgaaattggt cggtcttggt gaaggaatcg atgacttgga gccgtttgat ccaaatgatt
    12181 ttgtcgttgg attgttcaaa ggattactaa aagaagaata acccatgtct aaaaagcagg
    12241 agctgtgaca aaagttgcag ctccttgttt gaatgattgt ttttaacata gctgtgtttt
    12301 tgatgccttc atttttatac ttatttgtaa gcggttctca aacaatttcg ttctttttct
    12361 tagacttttt gattataatt agattcatat gaattggagg tcacttaatg atgaatttta
    12421 agcaattatt attgcatgtc aatgcgcgcc cttttatcga ccaagctcga tttggtatag
    12481 aacgggaagg acagcgggtt gatcttgcag gaaatctagc aaaaaccgat catccagcaa
    12541 tctttggcga tcgatcctat cacccctata tccaaacaga ttttagcgaa acacaaacag
    12601 agatgatcac ccctgttacc gattctattc ccgaattatt tcagtatctc gctgctgttt
    12661 atgatgtgac tgctcgttct ataccgaaag aagagatgat ctggccatta agtatgccac
    12721 ctgccttacc ggaaaaagac gaagagatca ttattgcaaa attaaaaaat ttcgaagatg
    12781 tcttgtatcg acgttattta gcaaaagaat acgggaagcg aaaacagatg gtaagcggta
    12841 ttcatttcaa ttttgaattt ggcgatgagt tgctaagaac attgttcagc catcaggaag
    12901 aatttcaaga tttttccgaa ttcaaaacag aactttattt gaaaacagcg agaaacttta
    12961 tgcgctatcg ctggatgatc acttatttat tcggtgcttc accaatgagt gagaagaact
    13021 actttttaga tgaatcacat ccgcaagaac ctgttcgcag tattcgcaac agtgcgctgg
    13081 gctatacgaa tcatccaaat gtgaaagttt cctatgcttc tatgaaacag tatttagcag
    13141 atatcgagcg aatgatcgaa gaagggaaac tttcggagga gaaagaattt tatacaccgc
    13201 ttcgtttccg aggcggaaag aaagtcgcag atttagcaac aacaggtgtt cgttatattg
    13261 aattgcggaa tatcgatttg aatccttatg caagattggg tatcaatcca gagcaagttc
    13321 ggttcttaca attattcctg atgtacatgt tatggacaga agaaaaagaa gactgtgacc
    13381 aatgggtagc agaaggtacg actcgaaata acaaagtagc actagaacaa ccatcagatc
    13441 aaacagaatt tcatcaagaa ggtagagaaa ttcttgaagg aatgaagcaa atgctggttg
    13501 aattggattg gttggattct ctttatttag tagaggaagc attgactcaa atggatcatc
    13561 ctgaacaaac gttagcagcg aaactctatc aagaagcaca gctatcgagt cagcaagaag
    13621 ttgctgtggc attgggacat caatattata aagaaagcca tgaacgtccc tatcagttgg
    13681 ccggttttcg cgaaatggaa ctttctactc agatatttat gttcgatgcc atccaaaaag
    13741 gtgtccaagt caaagtatta gatgagtcgg atcaattttt gcgtctgcaa ttccaagacc
    13801 atgtagaata tgtgaaaaat gcaaacatga caagtaagga cagctatatc gtcccactta
    13861 tcatggaaaa caaaacagta acgaaaaaag tcttaaaaga agctgggttc cgggtaccag
    13921 gaggcgcaga attttcatcc atggaagaag cggtaaaagc ttatccgaga tttgccgagc
    13981 aggcatttgt gatcaaacct aaatcaacca attacgggtt aggtatcacg attttcaagg
    14041 aaggagctag tctggaagat tatcaagcag gtttagccat tgcttttcgt gaagacagtt
    14101 cggttttagt agaagaattt atgccgggaa cggaatatcg tttctttgtg atcgacggag
    14161 aagtccaagc catcatgttg cgagtccctg ctaatgttat tggtgacagt atccgaacag
    14221 tgaaagaact tgttgaagaa aaaaatagtg accctttgcg tggaacgaat catcgtgcac
    14281 ctttagaatt gatccaatta ggtgaattag aacaattgat gttgaaagaa caagggttga
    14341 cgatcgaatc agttccccaa gccaatcaaa ttgtttatct aagggagaac tcaaatatca
    14401 gtacaggtgg tgattcgatc gatatgactg atgaattttc tgaagcttac aaaaaaatcg
    14461 ccgtttctgc ggtagaagca ctaggagcta agattagtgg tatcgatttg attataccag
    14521 ataaagaaat cgatcctaca actgataaaa aagcatatgg gatcatcgaa gcaaatttca
    14581 atccagccat gcatatgcat gtttatcctt ttgcaggaaa aggcagaaga ttgacgatga
    14641 atgtattgaa attgttatat cctgaagtat tttaaaagaa aaagcttttg acagattgtc
    14701 ctatttgatg tcaatctgat caaaagcttt ttttgcatgt aaaaatttat gtgttttttc
    14761 gttttaaaat aaacgatccc agaagctttt tttctttttt ggtttttctt tttcagctgg
    14821 cgaagagttt tcttctgggt attttttttc gatatcaatc acaggttcat ttactgcttc
    14881 ttttgctgtt aagagcaatc cgaattcctc aggatttgca gtgacgtaat cgttgactac
    14941 agtgaaacgg ctattgtttt tcgttgctag ctggatatat tggttttgga cagaaagggg
    15001 tagagcccca ttcaagagta tggaagcatc tggatgtttt ttgagttctt ttaaaaagtt
    15061 ttctttgttt tttggttgga tcatttcagc aacagtcata ctaagatagc agcgttccct
    15121 gaatgtccct aaatatttat gctgttcttc agggttcact aaaggtgtac cataaagtcc
    15181 cttatccaaa tggcttttta catcatcttg tgccataaaa aataccctcc ttcttctctt
    15241 tgtctttctt acgattatag catattccca ataataccta aaacatatga aaaagcggtt
    15301 gcttttgttc aacgattcac ttaaaataag aatgaaaatc attctcaatt agaaaggtgg
    15361 attggatgcg ctacggacga ctagtagcat tattagttat tttaagtagt atttcattgt
    15421 tcatcggagt atcgaatgta caattgtcag aactgctcca gttagatggg caaagcttac
    15481 aaatcttgct agtgactcgt ttgccacgaa cgatttgttt gatccttgtg ggagcgacca
    15541 gtagtatttg tgggttgatc atgcaacatt tgacccaaaa taaatttgtt tcaccaacga
    15601 ctgcgggcac gatggatagt gcgcgtttag gtattttagt ggctatgatt ttcctacctg
    15661 gtgcatcctt gattgtccga tccttgacag cattttgctt tgcttttgca ggaacattgc
    15721 tttttttatc ccttacgcga ttgttcctcc agaaaaatca attgatgctt ccgttgattg
    15781 gagtcatgtt agggaatatc attggttcag ttgctacttt ttttgcttat caattccagt
    15841 tggtacaaaa tatgacttca tggcttcaag ggaattttgc gactgtgata cgaggaaatt
    15901 atgagttatt gtatgctgtt gttccattgt tgctcttggt ttggctattt gcttaccgat
    15961 ttacgatcat tggtctgggc gaatcgtttg cagtaaatct gggaatagat taccagaaga
    16021 tgcagttttt aggcattggc ttagtatcat tggctagtgc agtcatgttg atcatggtag
    16081 gaagcattcc ttttatcgga gtgatcattc cgaatcttgt ctctagaata tatggagatc
    16141 aagtgcacaa aacaattggc gtaactgctt tagcaggtag tttgttctta gtattttgcg
    16201 atcttgtcgc tcgcgtgttg atttttcctt atgaaatacc agtcagtgtg atcgttggaa
    16261 tcatcggtgg ggctatcttc ctttatcttc tgataagggg acgacgatat gcttaaaaaa
    16321 aagccatcta tttttattgg tatgcttgtt cttgttttat ttgttacagg aatgtacttg
    16381 acgatccata catatggaaa ctggcatttt gcatgtgcat tgaggagtaa gaaaattttt
    16441 gcatttatcc ttgtctcgct agctgtcagc agtgccacaa tcagctttca gacaattacg
    16501 cataaccagt ttttgactcc ttcagtattg ggacttgagt cgttatatgt ccttgtccaa
    16561 acggtccttt tcttctttat cggaggagtg acgatgcttc agcagacagg tacagttttt
    16621 ttcttattga acgttgggct gatggtcggg ctgagtctat tgttattttt ctttcttttg
    16681 aaaaaaatga gagcgaatct ttttttatta ctgatgtcag ggatgatttt aggtacgctt
    16741 tttggtagtg tcagtacctt tttacaagtc atcatggatc cgaatgaata tgatttgctt
    16801 caaggcagat tatttgcaag ctttggcaat atccagagtc agtatctttt gcctgcttct
    16861 ttgatcatta tcggctgctg gtacctgtta tttcgatatc gacatgtgct agacgttttc
    16921 catctcggaa atgaacaagc agtaaacctc gggatagaca cagatcgttt tgaatttttg
    16981 attttatgtt gtgtcagtct tttgacaggg acatcaacgg ctcttgtggg tccagttact
    17041 tttttagggt ttattgtcgc aaatatcagt tatcgtgtct tttctactta tcgtcatggt
    17101 cagctattta tcggaagctt tctggtagct atgctgtttc tgacaggagg acagctcgca
    17161 gtagagcaga ttttcggctg gaatacaaca gtgagtgtcg tcgttgaatt tgtcggagga
    17221 atttattttg tcacaaaatt gattcgcgaa aggaagagta tcctatgatt gatttacaaa
    17281 aggtcaataa actgtaccat ggaaaatcag tggttaaaga tgtacagtta acgattcctg
    17341 aaaagaaatt gactgctttt atcggtccaa atggtgctgg aaagtcaacg gtgttgtcga
    17401 tgatcagtcg tttgatacca aaagatacag gtgaaatcta tttagaccat aacgaagtaa
    17461 aggcttggaa atccaatgaa ttagccaaaa aattatcgat cctacgacaa tcgaatgaaa
    17521 taaatgtcca aatcaccgtg aaagaattag tagaatttgg acgatttcct tatacgaaag
    17581 gaaaattgac gacaaaagac gaggaaatcg ttcaggaatc actggaacac cttgggttag
    17641 aagaaatagc ggatcaatcg attgacactc tttcaggcgg tcaactccaa cgtgcgtata
    17701 ttgcaatggt gctagcgcaa gacacggatt atattttact ggatgaacct ttgaacaatc
    17761 tagatatgaa ttttgcggtt caaatcatgc agattttaaa aaatttagta caagaaatcg
    17821 ggaaaacaat tgttattgtt cttcatgata tcaactttgc tgcaagttat gcagacgaaa
    17881 ttgttgcaat gaaagatgga cagttattta cgcaaggaac gacccaagaa atgataaaaa
    17941 aagatgtatt ggatgaatta tacgaaatgg acatacggat ttgtgagatt gaaggccgca
    18001 gattctgtct ttatttctaa aactaacatt aggagagaag agatgaaaaa attagtagta
    18061 ggtatcttga ttctagcatc atttggttta gcagcatgtg gaaatagcaa caacaccagt
    18121 caggcagaca caaaaaaaag cagcacacaa actgaaacta cattgacgat aacagatagt
    18181 aatggagacc aaatcgaggt gccaaataat ccagaaaaag tcgtcgtatt cgacaatggt
    18241 tctttagata cgatggatgc tcttggtgtt ggagataagg tagttggagc agctacaagc
    18301 agccttcctg agtatctttc atcctataaa aaagtagaat cagcaggtgg aataaaagaa
    18361 ccagacttag aaaaaattaa tcagcttcag ccagatctaa tcatcatttc tggccgacaa
    18421 agagattttc aaaaagatct aagtcaaatt gctccgacca ttttcctttc tttagatgcg
    18481 aaaaatccat gggaatcttt ccagcaaaat gtcactgctt taggggagat ctttggtaag
    18541 caagaagaag ctaaaactca attagaggaa ttatctagtg caatcgatca gacgaaaaag
    18601 aaagcagaag ctactgacaa aaaagcacta gtcacacttg tgaatgaagg gcaattatca
    18661 gcctacggat ctggttctag attcggtttc atccatgatt tatttggctt tgaacaagca
    18721 gatgatcaaa tcgaagcatc cactcacggt caaagtgttt cttatgaata tgtgctggaa
    18781 aaaaatccgg atatcttatt tgtagtagac agaacaaaag ctattggtgg agacgacagc
    18841 aaagatgata tttctgccaa tgaactggta gcacaaacga atgctggtaa aaatcagcag
    18901 atcatctccc ttgaaccaga tgtctggtat ttaagcgggg gcggtttaga atcaatgaaa
    18961 ctgatgatcg aagatgtgaa tcaagcattt aaatagcata aataacagag gattaaactc
    19021 tcatactatg taacaataat gtttcttaca ttcttaaata gcaagagcct atcctcaaag
    19081 aagttatcaa aaaccatccg taaaatcgta ttgatgattt tacggatggt ttttatttat
    19141 ttgagaaatc ttttttcaac gtgaattcat tatctacatc atacgggttg attctagaat
    19201 ggggagtggc aaaaaatagt gtgatccatt ttttcagcat caagatcgcc tcctttgatt
    19261 tgaatcaaag gtacaaagcg aaacttagat aaaacttaaa tttagatatt tttattttgt
    19321 accgatctct tctttaaacg atgttccatc tgctgcttct cggcaataag tccactagac
    19381 tagaaaatat gagaagctat tttctgtcca gcgttcttat tactcaaagc aaatcgcagt
    19441 tgtcacaatc tcttctaaac gatgttccat ctgctgcttc tcggcaataa gcccactaga
    19501 ctagaaaata tgagaagcta ttttctgtcc agcgttctta ttactcaaag caaatcgcag
    19561 ttgtcacaat ctcttctaaa caatgttcaa tcagctgacc ttcggtatta gctcaaagca
    19621 ctgatttcac aacctctatt taggcatgtg tctcagcaag cggttgatag ttgatgatct
    19681 gcatttttcg ataaaaatcg gcgggaagct tactccaccg ttttaataat tgatagaaat
    19741 aactctcttc tgctttgatt ttatactcgc ttaatatcaa tccaaaacta ttcgtttttt
    19801 ttgaagctaa ttttttataa atatccaatg ctttggtttt atcttcattg acaaagagtg
    19861 tttttacttc aatataagaa ccctcgatat tttgtgtttc ttcgataaaa tagatgtttt
    19921 ttatatattc cttcatagtg attcctccaa agaagtcttt tatttgataa gtttactcta
    19981 ccgaagagtt gttaataatc cgtgaacaaa aagtaattct ttttccaata gttgttaaag
    20041 gttttttatt ttttatagta ttttttgtta tttaagaaag gaataaggtt aaacaaataa
    20101 caggttgctt tttgggtctt tttccgttca agaaactgaa cgaagaaaag ggaaagttgt
    20161 ctcttttgtg ataagagaaa tcataataaa cgaatgactt actttccaat aaattgagaa
    20221 cagtcagaac cagacaaatt agttgcatct gatgaataaa gtgattattc tatgacatga
    20281 ggtgatacag atgaaattag aagtgacaaa agaagcacaa gaagtattga agaataaatt
    20341 agaagcagac gatcaacttt tattagatat cgaaaacggt gacggtccat ttgcagaaag
    20401 ccaagtcagt tgccaattgg atacggcatt tcgattgatc attgtcaaaa aagatacaca
    20461 aacagatcta agtctttatt ctgtagtggc tgatacacca gttggaccaa tcaaaatcaa
    20521 agacagtgca atactttaca tggatgatcc atccacactt gctttagaac caacttataa
    20581 tagtttacaa ttaaaaggac caagcggctt gagaaaaggc aacttgcaag ttgttcgaaa
    20641 agactagagg gataaaatgg gaaaattggc gatcatcagc gacctacatg tggacatcaa
    20701 taaattcggc gaatcagagc tgatgcagct ttggcaagtt ttgcaaaagc acaagatcac
    20761 tcggcttcat ctagccggag atacggctaa taaagtagac cgttgcctag ctgttgtcga
    20821 atttttcgtc aataaaggat tatctacgac atttcatttc ggcaatcacg agttggcaga
    20881 tgtgcccaat gaacagatga tggaccattt tccagaccca cattttttaa atgaacggta
    20941 tattgcttta aatgagcaga ccgttctttt agggatgaat ggctggtacg actatcagtt
    21001 ttccgaattg aaagattacg aggcaatcgt acgaatgaag cgtttgtatt ggtatgatcg
    21061 gttcatccag cgtgggaaaa cagatctcga ggtcaatgca gaaatgcttg cagctgcaaa
    21121 aaatttgcta gaccagctgg aagcaaaaaa acttgaggtg attttatcca ctcatttcgt
    21181 tcctaaacgg gcatttatca tgtatcaatc tgctccttat gagcgttgga acaaattaaa
    21241 tgcattttta ggatcagaat cattcggaga attacttgac cgttattcaa atatcaaaca
    21301 agtagttttt ggccatacgc atcgtcgctt tgaagataaa tccatcggtc acacgattta
    21361 cagctgcaga ccttttggtt attattatga atggcagctg acccgagatt ttgtcttgaa
    21421 agaacagttg ctagacagct atgatcctat gaaattacgt gtcctcttgc gtgcccatca
    21481 cccagctttt caggcctatc aaacacaaca tttgcaagag gaatttgaac aagcgatgac
    21541 aatcgttccg tattgagaca gcattagtaa tgtgtaaaag aaaatacctt gtaaaacata
    21601 aggataagta agagcagtag atccatttat cgtggatatg ctgctttttt tgcggaaaat
    21661 aatcagcgaa tgtttatttg atcggatgat ttgtaactcg cagagtacta gatgcaagcg
    21721 tgtattcttt ttttgaacga taatcacaaa aaaaaatata atatacattt tttatttaat
    21781 tataattaat attgattgaa gtctaggcag tcaagtcaca ttttgataga taggaggggg
    21841 acttacgaat tattttaaag gctatgacag ctgtatttct agattgtgtt tgcatcaagt
    21901 tgcaataaaa actagaaatc aaatcgggct gataatcatt tataactaat cgatacatag
    21961 gaccaaatat aggtctatgt tcttttattt cataagtatc gtaaaacaga attttgctat
    22021 ggattaatcc aatcgactga tatgtttagt aaataaagaa agaggaatgt caatgatgaa
    22081 aaaagaaatc gtattaacag cagcaatgat gttattcagc atggtagcaa gtacgacttt
    22141 tgtttctgca actgaagtat acccaaagga atataacaca gaaggaacga ttacatttga
    22201 agcaggagat gagggtgtaa ctcctcctgt tgatccagag aatcctgatc ccaataaacc
    22261 tgtcgatcca tcagatcctc caagccctgg aacaggaggg gcattatcga ttgattatgg
    22321 atcaaaattc aaatttggga ctcaaaaaat ttctactgcg gataaaacgt attatgcagc
    22381 tgctgatgtg atgaacgatg ggtctagaaa accgacatat gtccaagtga cagataggag
    22441 aagtacctta tctgggtgga aattaagtgt ctctcaacca gaacagttta aaactgccag
    22501 tggggatgaa ctagttggag cacagctgaa atttacgaaa gggcaggctg tttctttggt
    22561 tgatccaaca tatacgccgc aaacggtgaa ttctgaatta acgttgacac cgggaggaaa
    22621 caatacgtta gcaattaatg ctaaatcagg aacaggtgtg gggacttggg tctatcgatt
    22681 tggtgcaaat gaaaatgaaa atcaagatgc ggtacagctt tcggtacccg gtaaatctgt
    22741 caagttagcg caacaatatt ccactaaatt agtttggaca ttagaagata cacctaacaa
    22801 ctagtttact gaaaagaact gttaaaaata aatacgtagt catattgtct tgcgaggtaa
    22861 tcgagcaaaa attgtcaaag gctaggctaa atttgtttgg atacgaatag ttcatctagg
    22921 aatttaacga tcaggaggaa aagatatatt gaaaaagagg aggatcgtgc tcattttaag
    22981 cagtctctta gtgactaata tctttccgat catagggtac tctttggaat tgaatcagtt
    23041 ggagcatgga aatagaagag acgaagaaag caaactcact tcgacattcg acagtttaat
    23101 agaatccaac cagacacaag aaagcagtga ggatttaagt atttcgagta gtggagagac
    23161 cactgacaac gtagaagctg agggttcgga caaacaagga ctagaagatg caccaatttc
    23221 tgcggttgag ctgcctgacg atcccaatat tatttctatc gataaaattt ttcaaacacc
    23281 tatcggtact agcacgtcca tattggaaaa tgggaagtta ctgcagttga acccagcaga
    23341 aaggtctcaa agaggagcta tttggtcaaa taagaagatt agtttactct cggattttac
    23401 atttaaatct tatttatact taggaaatca acgagataga gcgggagatg gcatgacctt
    23461 tacattgact ggcgatccta gaatggctag taatcccagt caagttattg gatcgccagg
    23521 tatgggaatt ggctcatatt ctactcgttc tggccaacct tacattgcga atgcgctctc
    23581 gattgagttt gatacgtata aaaatagtgg ttcttctgat cgaatggatc gagagataac
    23641 tgctgataat agagggcatg gacatgtcgc ttttgtcacg cctaaaccaa ataataataa
    23701 ttattctgga gagcatactg gcgtgacggt agctcctaca tttctttcta atggcacatg
    23761 gcgcttgtta ataattaaat gggacgcgga gcaaagaagt cttacttatg atttggaagg
    23821 tgtcggtcac tcttctcgga ttatacctga tctcattagg cagtttggtt ctacagaagt
    23881 aaattggggg tttacttctt caacaggtac tttttttcaa gaaaatgctg tcgctgtcac
    23941 gcgacttcca tcgaatgtca catcaacagc tgatgtaaaa gtcaacgata gtgattatgg
    24001 ggccatcgct gaagctggag gaaacgataa gataactatc agaaatacat tgaaggtcga
    24061 gggggatttt cttgaatata agaaaatgca gactagtatc gacctcccac aagaattaac
    24121 tattcccgag catatcttga tcaatggaaa tcaaattgat gccaaagata tcttgataac
    24181 cggaaatcga gtcacgctaa atctgacaga ttattttatt gctggagata cgttaataat
    24241 cgaattggag acaactttgc aggaagtaat tcctgaaaaa gtactcacta tgcattttga
    24301 ataccttgaa aacgggaatt tgattgagca atcgaatgaa ataaacctaa agatcgcaaa
    24361 gctgaaggag atagatatcc atgtttatta taaagataaa gacagtcaga ttgatattgc
    24421 tgaaatgaaa acaatcactg ggaaaatagg agagaagtat aaagaaactc ctattgatat
    24481 tgaagggtat gtttttgact cggattcagc gaatacagaa ggcatcttct ccgaaaatac
    24541 agaggatatc tatttttatt acagaaaagg caaactttat ctctcaactg ctcctcaata
    24601 tgtcaatttt ggaaaacata aaatatccag tagaccatta agtgaattcg gacagttttc
    24661 aggtgggttg aaaattatag atgaacgggc ttttggaagt tggaaattac aattgaaaca
    24721 agagaaagtt cttacaaatg gagattttga gcttccagaa gctctttcct ttgttacctc
    24781 tgaaaataca acggttatag ggacatccgc tgttacgatt ttcgaaagtg atcaaaaggg
    24841 tgaaagcgat ttgtcctctc ttttagattc tacagctcat cgtggaatca gaatagatat
    24901 tcctgtagaa aaccaaagaa tcggaacctt tgaggggaaa ctatcttgga tacttgcaga
    24961 tgtcccagga aattaacagg aagagaagaa tataacaaaa ttattgagtt tcaagaaggg
    25021 cacaggtacc ataggctctt gtgtcccaca gagacaagat tttgttatag tcttctctta
    25081 catatgatta aaggagcgat tttcttgaga ccaaaacaac aattatttat aacactccta
    25141 gttattttag gggcactttt taacaatata tcagtgtcag ctagtgcatt taatttttca
    25201 gtgacgccga taacttcaga gaatcaaatc gacaagagaa aaacttactt cgatcttcaa
    25261 cttgatccgg atcaggaagt agaagtaaaa gcggaattga gaaatgatac agaaaaagaa
    25321 gtgaaaatcg atatttctgt gaatagcgca accaccaatt caaatgtgat ggttgaatac
    25381 ggaaaaaacg agattgaaaa agacatgagc ctgatctttg atctggtaga ttatgtgagc
    25441 tatccacaga tagtgacgct aaaacctaaa agtgtccaaa ccgttgcttt tcatgtcagg
    25501 atgccgaatg agcgatttga tggtgtattg gctggtggga tcacattcca agaaatccag
    25561 acggaaaagg accaaacaga aactaaggat caaagcttat cgattgagaa tgaatacacc
    25621 tatattattg ctttgttgat gcaacagaca ctgaacgaag ttgctccgaa ccttactctt
    25681 catgaagtta aaccagatca aatcaatgca agaaatgtca tcttagcaaa cgttcaaaat
    25741 gatcaaaaaa cctatatcaa tcaagtagtt attgaaacaa aaattacaaa aaaaggacat
    25801 tctgaagttt tatatcaaga ggaaaaagaa ggattgcaga ttgcgccgaa tacaaatttt
    25861 tcttttccaa ctgctttaaa tggtcaaccg ctaaccccag gtgaatatca ccttacaatg
    25921 actgttttag gaaatgaaaa tgaaaatgga aaattttcga gaaaaaaagg aaatactacg
    25981 atcaactata ccaatcaatg ggtatttgaa aaagatttta caatagacgg aaaagtagcc
    26041 aaggaattga acacgacgga tgttacgatt aaaaaagaca ataattggat ttatatctta
    26101 gtagcttcac ttttcttatt gtttatttta ttatgcatac ttttgtttgt tttgagaaaa
    26161 aaagaagaga aagaaaagta aggttaagat aacaaatagt aaatttttat tattgtagga
    26221 tggttgggct ctttttataa caatataaaa tataccattt tattaataaa aatgca
//
LOCUS       DADVXM010000032        25706 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.033, whole genome shotgun sequence.
ACCESSION   DADVXM010000032 DADVXM010000000
VERSION     DADVXM010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.033"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(174..1754)
                     /locus_tag="KB927_001415"
     CDS             complement(174..1754)
                     /locus_tag="KB927_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBB6840340.1"
                     /translation="MNNPELKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2155..3531)
                     /locus_tag="KB927_001416"
     CDS             complement(2155..3531)
                     /locus_tag="KB927_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBB6840341.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3659..4777)
                     /locus_tag="KB927_001417"
     CDS             complement(3659..4777)
                     /locus_tag="KB927_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6840342.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            4919..5353
                     /locus_tag="KB927_001418"
     CDS             4919..5353
                     /locus_tag="KB927_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6840343.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5431..5964)
                     /locus_tag="KB927_001419"
     CDS             complement(5431..5964)
                     /locus_tag="KB927_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBB6840344.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6058..7236)
                     /gene="mutY"
                     /locus_tag="KB927_001420"
     CDS             complement(6058..7236)
                     /gene="mutY"
                     /locus_tag="KB927_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBB6840345.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7229..8026)
                     /gene="recX"
                     /locus_tag="KB927_001421"
     CDS             complement(7229..8026)
                     /gene="recX"
                     /locus_tag="KB927_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBB6840346.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNRGKSQKELLRKIQQTLMTKGFSQEVIQQAMADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8133..9515
                     /gene="rlmD"
                     /locus_tag="KB927_001422"
     CDS             8133..9515
                     /gene="rlmD"
                     /locus_tag="KB927_001422"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBB6840347.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(9689..10267)
                     /locus_tag="KB927_001423"
     CDS             complement(9689..10267)
                     /locus_tag="KB927_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBB6840348.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10589..11059
                     /locus_tag="KB927_001424"
     CDS             10589..11059
                     /locus_tag="KB927_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBB6840349.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGEYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11167..12393)
                     /locus_tag="KB927_001425"
     CDS             complement(11167..12393)
                     /locus_tag="KB927_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6840350.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(13147..13347)
                     /locus_tag="KB927_001426"
     CDS             complement(13147..13347)
                     /locus_tag="KB927_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6840351.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(13481..14089)
                     /locus_tag="KB927_001427"
     CDS             complement(13481..14089)
                     /locus_tag="KB927_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBB6840352.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNAAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(14174..14644)
                     /locus_tag="KB927_001428"
     CDS             complement(14174..14644)
                     /locus_tag="KB927_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBB6840353.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(14692..15606)
                     /locus_tag="KB927_001429"
     CDS             complement(14692..15606)
                     /locus_tag="KB927_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6840354.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKNVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            15752..16555
                     /locus_tag="KB927_001430"
     CDS             15752..16555
                     /locus_tag="KB927_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBB6840355.1"
                     /translation="MTTKQLIISSFIRFKDLKETRNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKELR
                     SFLSKASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            16733..17680
                     /locus_tag="KB927_001431"
     CDS             16733..17680
                     /locus_tag="KB927_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBB6840356.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(17748..18041)
                     /locus_tag="KB927_001432"
     CDS             complement(17748..18041)
                     /locus_tag="KB927_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBB6840357.1"
                     /translation="MELTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(18069..18734)
                     /locus_tag="KB927_001433"
     CDS             complement(18069..18734)
                     /locus_tag="KB927_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBB6840358.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(18874..19506)
                     /locus_tag="KB927_001434"
     CDS             complement(18874..19506)
                     /locus_tag="KB927_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6840359.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDCPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(19513..20580)
                     /locus_tag="KB927_001435"
     CDS             complement(19513..20580)
                     /locus_tag="KB927_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6840360.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEIAKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(20577..21308)
                     /locus_tag="KB927_001436"
     CDS             complement(20577..21308)
                     /locus_tag="KB927_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBB6840361.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            complement(21476..21955)
                     /gene="greA"
                     /locus_tag="KB927_001437"
     CDS             complement(21476..21955)
                     /gene="greA"
                     /locus_tag="KB927_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBB6840362.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(22091..23266)
                     /gene="mltG"
                     /locus_tag="KB927_001438"
     CDS             complement(22091..23266)
                     /gene="mltG"
                     /locus_tag="KB927_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBB6840363.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPNGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEKAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            23431..24591
                     /locus_tag="KB927_001439"
     CDS             23431..24591
                     /locus_tag="KB927_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBB6840364.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            complement(24631..25578)
                     /locus_tag="KB927_001440"
     CDS             complement(24631..25578)
                     /locus_tag="KB927_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBB6840365.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDME
                     KQVTFIEGDVSDPQLMERIMKQYQFAYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFASEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
BASE COUNT         7742 a         5235 c         4150 g         8579 t
ORIGIN      
        1 taactagcac cacgggtatt tttatatttt tttgattaga catttctatg attttaatat
       61 agtaaaaaga gccgtcacgg aaaatccgtc acggctctaa acaaaatatg agaggctgtt
      121 tttgtttggc tattcttatt acttgatgca gggcagcttg tgtcaagact tctttacatc
      181 aaacttttta attttacatt aggatattta tccgcaaacc agcgttctgc aaattggttc
      241 tcgaataaga acaatggttg gtcgaaacgg tcacgagcca agatattgcg acttgaactc
      301 atcttctcat ccaaatcttc tggatcgatc cagcgagcga ttttgtgtcc cattggagac
      361 atgattactt cggcgttata ctcatttaac atacgatatt ggaatacttc gaattgtagc
      421 tgaccaacag ctccaatgat atattcttcc gttagatatg ttttataaag ctgaatcgct
      481 ccttcttgaa ctaattgata gattcctttg tggaaggatt tttgtttcat gacatttttt
      541 gcagtcactt tcataaacag ctctggagta aatgaaggga gttcttcata agcaactttt
      601 agttttcctt cgaacaatgt atccccaatc tgataattgc ctgtatcata tacaccgatg
      661 atatcgcctg ctactgcttt ttcgacgttt tctctcgaat ctgccataaa ttgtgtgaca
      721 ttgcttaatt tcagtttttt atttgtacgt tccaaccaga catccattcc tcgttcgaat
      781 gttccagaac agattcggac aaaagcgatt cggtcacgat gggctggatt catatttgct
      841 tggatcttga atacgaaacc tgaaaattct tcctcataag gacttaccat ctgatcatct
      901 tgtgttttgt gtccataagg agctggtgcc aattcaacga aagtctctaa aaaagtctgt
      961 acaccgaagt tagtcaatgc agaaccaaaa aatactggtg tctgatcgcc acgagcaatt
     1021 ttttcttgat taaatgcatc tccagcctct ttgattagtt ctacttcttc taagacttgt
     1081 tcatataagg aattttcagt tagaggatga ttttcgggaa gcagtccatc ttcatccaat
     1141 tctactaatc gttcatcctg ataattttcc ggacgataaa actctacacg attatggtag
     1201 atatcataaa gaccttctag ccctttaccc ataccgattg gccaattcat cggataagat
     1261 tcgatatcta atagctcttc taattcttct aacaattcca atggttcacg accatcacga
     1321 tctagtttgt tgataaaagt aaatatcggg atgccacgtt tttttacaac ttggaataat
     1381 ttctttgtct gtgcttcgat cccttttgca ctatcgatta ccatgaccgc actatccacg
     1441 gccatcaaag tacgataagt atcttcagaa aaatcttcat gtcctggtgt atccaagata
     1501 tttactcgtt tcccttgata atcaaactgc ataacagaac tagtaacaga aatcccacgt
     1561 tgtttctcga tttccatcca gtctgatttg gcaaaattac ctgttttttt gccttttacg
     1621 gtcccggctt gacggatagc cccaccaaac aatagtaatt gttctgtaat cgttgttttc
     1681 ccagcatccg gatgggaaat gatcgcaaaa gttctgcgat tgtccacttg ttgctttaat
     1741 tctggattat tcataaccta actccatttc ttccattcaa ttatttatat tttctctagg
     1801 cacagattgt ccgatctctt aaagaaagac aatttcatat agggctgtga caaaagccgt
     1861 gtagcagtct ctttttccga gtaaacggcg ttctagagac agcctatcag caataagccc
     1921 acccaagcca aaaatacgaa aagctgtttt tgcttggctg ctcttattac ttaatgcagg
     1981 atagcttttt cacaaccttt gtcaactact acaactgaat cagtatagca tggattcatc
     2041 gaatgaaaaa gccaccaaac cataagagtc aaatattttt ttgtcagctg actaaaagaa
     2101 aagacgtgtt gcttgtttat tcaagcaaca cgtctttcat aaccaagttt ccaattatct
     2161 tcttggctcg tcatcttcga attcttttct gaagtatctt cgttcttctt caggttccgc
     2221 ttctgtttct tccggatcat gaaaaatgac acggatttta aggattcgag aaccttccat
     2281 ttcttcagaa accagcgtaa tattatcgac atcaaacgat aacttttcgc cttcatccgg
     2341 aatcatgcct aatgctgtaa tcaaataacc agccatcgta tctacatcac tcatatgcag
     2401 atcactgtca aaagcttcat tgaactcatc aatcagcata cgtccttgga tgatatattc
     2461 gtgttcatcg attttttcat aaagattctc aacttcatct gattcatcat cgatttctcc
     2521 gacgatttct tctaaaaggt cttctagtgt tgctaaccca acgacgccgc catattcatc
     2581 taataaaata gccatctgat tctgcgtctt tttcatttca tataacagat catcaataaa
     2641 gaccgtttca ggaacgaata aaggctcctg catgattttc ttgatatcta aattatcaaa
     2701 accgaattta tgggcagctt ttagtaaatt ctttgtatga aggattccga ctactttatc
     2761 tttgtcttcg ttataaacag ggattcttga atagttttcg gataaaactt cattcacatt
     2821 ttcttccaca gtgtcgttga tatcaatcat aaatgcatcc gttcgtggga ccatgacttc
     2881 tcgggcaact ttcgtatcaa gagaaaaaac cccttggagc atttctaatt cttcattatt
     2941 caatacgcct tcgttttcaa gcatataacg catttcatct ctggtcattt ttgaatcttc
     3001 atcatcaaaa gtcatcggcg tgatacgcgc caataaactt gtggaagcag aaagcagcca
     3061 gacgaagggc ttagctacta caccaatcaa gcgtatcagc cctgaagtga actttgcgac
     3121 ttcttctgat ttatttaaag caatacgttt agggtacaat tctccaaaaa caatcgatac
     3181 ataggtcaaa atagccagca caatgatatt tgcaatattt tttgccgctg tgccgccacc
     3241 taataccgga gctaaccgtt ccgataaagt attagctagt gaagcaccag acaaaatgtt
     3301 gaccaaagtg attcctactt ggattgtcga taggaaatta tttggattct gcaatatttt
     3361 taaaagcttt tgagatttca catctccttc atcagctttt tgctcgattc gattcttatt
     3421 gatcgaaaca acagcaattt cggaagctgc taaaaaagca ttgatcaatg tcaaaacgat
     3481 caataataaa atctgcgcta acagcgactg actctcaggg tcagcattca taatcgcatt
     3541 ctctccttat aaaattaatt tttagtttac gatagaaaaa aacgtggcac tatagccacg
     3601 ttaaaatggt atcacaaagc aattttcttt gcaataaaaa caagtgtact aaaactacct
     3661 acgaggtcgt agcaattttc ttcttgtttt cattttgctt gtcttctttg acgattttga
     3721 ttatatagga aatgatcgtc ttgcagattg cgtaaaaagg aacacctaag aagataccaa
     3781 gcaatccggc aatatttcca gctactagaa gaacgataat gatcgttaat ggatggattt
     3841 tcagtgattt cccaattaca ttaggataaa tgatattccc atccaactgt tggacgatta
     3901 gcacaaccac acaacaaagt aatgctttta ccggatcatt gaagactgtt actagaaatg
     3961 caggtgctag tcctagataa ggtcctaaat atggaattag gtttgtcaat cccgcaatga
     4021 ccccaaataa gaaagcataa tccacaccaa ttaccatata tcctaaaaat gtgaaggtac
     4081 caacgaataa acattcgatt gcttgtccgc taatgtaatt agccaatgtt ttattcagtt
     4141 gccccaataa ctccacaatt tggtttcttc ttttttctgg gaaaaactgt tggatgtttg
     4201 gcactagttt ttctccgtct ttcaacatat agaacaagat gaatggtgct gtaatgatta
     4261 ctacggttgc cgaagcgatc gttccaacga tcgaacctaa actattggat actccactaa
     4321 ggaattgctg aatgattgtc ccgtaagaaa tgtctaattg ctcaaaatat ttattgatat
     4381 ctacttcctt gaacaaaggc aattcggcta cctcttttaa ccagctttct acctgtttga
     4441 tgaaatcagg catattagat gccaatgagg aaatttgctg tactagactt gggatgacac
     4501 taagtaaaat ccaaataatt gctgcaacta aaaggagcag cacaattgcg acagcccata
     4561 ttcttttgat ttttgctttc atcaacagct tgacaatagg attcaataaa tagtaaagaa
     4621 agcctgcaat cagtacaggt gcaaataacg tggaaaaaaa tgtcccgatc ggttcgaaaa
     4681 taaagtttat ttctgatgaa atcatgatca atgcagctat gatcaataat tcaagcgacc
     4741 aaaacattag tttagactgt ctaagttttt caaacaatag atttcctcct ttctttctta
     4801 ctagtatata ttatattcgt taaaaattct tttattcttt ttttattttt gaaaacttgc
     4861 catacttttt atttgtttta ttttccagta tactatacga aaggaaggtg gctagaccat
     4921 gaaagttgta caaacaaaag atacaatgag caatatttac ttagatgctg tacggatcag
     4981 gcatcaagtt tttgtagtcg aacagggtgt gcctttgtct cgagaaatag acaaagatga
     5041 agcccattgt atccacttcg tcctgtactc agataaaaaa gaaccgcaag gaactgtacg
     5101 tcttttgcct ttagaaaacg gaaaaatgaa attacagcgg atggcgattc tttctgaata
     5161 cagacaccaa gggttaggaa aaatactgat tgaagaagca gaaaactttg ctaagaatca
     5221 aggctataat acgattttat taggggcaca gtccacagct gaaacttttt acgaaaaact
     5281 aggatataca gcttacggcg atccttttga agatgctggc atgcctcata tttatatgaa
     5341 aaagacttta taaaaattta tttcgaaaaa agcaaaaaac agcaagcttt tgagaaaaat
     5401 ctctcactgg cttactgttc ttttttgtgt ttacttacgc gacaattgct tgtaacggtt
     5461 ataccaaata tcaatatagc cttccgagaa cgggccatct ccattattga tccagtcaac
     5521 cagaatcttc acattttctt ttaggatgaa gtcaatatcg ttcggataat tcatcatttt
     5581 gctgtgcatc tcatattcat cgacatccaa tagtcgtttc tcgccgtcag gaaatacctt
     5641 gatatccaag tcatagtcga tatatttcaa ggcctcatcg tccagcaaaa aaggtgaagc
     5701 tagattacaa taataggaaa cccccttttc tctgatcatt gctattacat tgaaccagta
     5761 ttttttatga aaataaacaa tcgctggttc gcgcgttacc catcggcgtc catcagattc
     5821 agtgactaat gtgtgatcat tcacgccgat catagagtgt tcgcttgttt ttaataccat
     5881 ggtatctcgc cacgttcgat gcaatttgcc gtcgtgcttg taactttgga tcgtcacaaa
     5941 ctctccttct tttggaactc ccatagcaac ccttccttaa gcagcatttt gtgctttgtg
     6001 tttgggtgtt cattacaccg acatcataat tattatatca ataaaaatga gctttgccta
     6061 gaaaggattc ctattgtttc gatttttctc taactgatct accagtttca tttggacctt
     6121 aggaaaaacg accgaatcaa atgcatcagg cttcaaccac ttcgaagttt tgttctcggt
     6181 aaattcttgt tctgctccct cggttgcccg tccgtaaaaa aggagaacat gccatttcag
     6241 atgactaaaa atatgagtaa cttctcctaa atgtcgtgtc tgccaaacaa agagttcctg
     6301 cttttcaaat gggagatttt gctcttcttc tgctactagg tcatcaaaca gatcgatttc
     6361 tggctttgtt tcccattctt ttttcaatcg ctcatactcc tcttgtgtca cttccatcat
     6421 tggaaatgtc cacatattcg ccagcaattt ttggctatct ctttcttcaa aataatacgc
     6481 tccagaatga ttttgaagag ccgcactgat ataataaacg tcttttggct ttgctttttt
     6541 tgtttttaca ggaaaactcg tttggattcc tcgtttgtta gctaaacaaa aggcttggat
     6601 cggacaagtc tcacactttg gagaagttgg tgtacagata gctgaaccta gatccatcat
     6661 tgcttggttg aattcacctg gatgcttttc atcaatgatt ttccgcatcg cttcatcaaa
     6721 gattttcctg ctagaagctt ttgcgatgtc tgcttcaatg caaaacaatc tgctgactac
     6781 tcgcatcacg ttgccgtcaa ccgcgggttc tggaagtcca aatgcgatac ttgcaatcgc
     6841 gcctgtcgta tatggtccta ttcccttcaa tgagctaatt tcttcaggcg tttgcggcat
     6901 ttccccatca aattctgaca tgatctgttt agcagcagct tggatgttcc gggctcttga
     6961 gtaataacca aggccctccc atgcttttaa aagcttttct tctggagcat ttgctagctc
     7021 ttcaattgta ggaaaccatt ccatgaaacg ataaaaataa tcgatcactg tgtctactct
     7081 ggtttgctga agcatgatct cagagatcca gatacgataa ggatcacgat tatagcgcca
     7141 aggcaggttt cttttttctt gttcatacca ttgaatgaac tgatcttgaa attcttttgt
     7201 ttctttatct gtccattttt cccattcttt attcactttc ctcttccttt tccgtaatga
     7261 atcgctggat catatccaaa tcaaatcctt tttgatataa gctttgcttt acttttagat
     7321 ttcttttttt aggttcaaac cttaaatttc ttcgccatag tttatctcct tgtttgacta
     7381 aataatcata ttctatttct tgatctgctt cttgcggaag atcagccatc gcttgttgga
     7441 tcacttcttg agaaaaacct ttcgtcatca atgtttgttg gatttttctc aataattctt
     7501 tttggctttt tccgcgattt tttccaaacg ctttttcggc tgtctgatgt gcattttgaa
     7561 cttggtcttc aaatgtatat tggctgagcg cttgttcaat gatttcaggt ttcaaacctt
     7621 tttgctgcat ctgctgcgct aatttctttg gtcctttgtc acttaagcgc atattcgtgc
     7681 gcacataact ttccccatag accaaatcat cgacaaggtc caattctttt aagcgggcta
     7741 cgattttatt tcgatcttct tgaaggattt ccttttcttt taagtatgtt cggatttctt
     7801 tttccgatcg caactgataa cttaagtaat tcattgctag gtgaaaaccg aaatcagctc
     7861 cgctactctt cttgatctct tggatagttt cttcgtctaa ttcccgtcct tttaataatc
     7921 gatagcgtac taatacatct tcagatactt gtaaagcttc tccttcagat aaatctacgc
     7981 gatagaaagg gcctttgcct ttactgattc tcgtaacggt taacataaac atcctcctcg
     8041 aacatatatt ctctatcata ccacagaaaa tccccgtaat caggtattat atgttagaat
     8101 aaaccacaga aaaaagaaaa agggagatac ttatggcaga aacaattgtc aaaactggac
     8161 aaacggttcc tttgaaaatc aagcgtttag gcataaatgg tgaaggaatc ggttatttca
     8221 aacggttgat catatttgtt ccatatgcac taccaaaaga agaagtacta gtgaaaatca
     8281 cgaaagcaac tcctcgctat gcagaaggag aattaataaa agtcaaaaaa acaagcaaag
     8341 atcgcgtagt ggcaccatgt cctgtttact atgaatgcgg tggctgtcaa ttacaacact
     8401 tagcttatca agctcaattg gattttaaaa aggatctgct tttgcaagca ttggaaaaat
     8461 tcaaaccagc aggctttcga tcttatcaac ttttgccgac gatcgggatg gatgagcctt
     8521 ggcattatag aaacaaagca caatttcagt tacgaaaaaa taagcagact caaaaaattg
     8581 aagctggttt atacgaagca aactctcatc agttagtccc tataacagac tgcttggttc
     8641 aagaacctcg aacacaaaaa gtaatgaata ctgttgttca actattgaat aaatttgatg
     8701 cacccatcta tgatgaacgg acaaacagtg gaatcttccg cacaatcatg gttagaatcg
     8761 gtgttaaaac tggggagtta caagttgttt ttattactcg cagtaaaaaa ttcccgcaaa
     8821 aaaacgcaat gatccgtgag atcaatgaac gactgcccga agttgtttca atcatgcaaa
     8881 atgtccaggc acaaaaaacg tctctcgtga tgggggatga aacgatccac ttatggggaa
     8941 aagaagccat tgaagaacaa atcaatgaag tgactttcga tctttctcct cgtgccttct
     9001 ttcaactcaa tcctcagcag accgaattgc tttatggcga aggaatcaaa gcattagatg
     9061 tccagcctaa tgaaacgatc gtggatgctt attgcggagt tgggacgatc ggcttaagtg
     9121 tagcaaaaca agccaaagaa gtacggggaa tggataccgt tcctcaagca atcgctgatg
     9181 caaaaaaaaa tgcggaaaga ttaggatatc acaacactcg atatgaagtc gggacagcag
     9241 agcaagttct gcctaaatgg ttgaatgaag gttttcagcc tgatggtatc atcgtagatc
     9301 caccacgtac gggtttggat aacgcattga tccaatcatt attgaaatac cctccaaaaa
     9361 aacttgttta tatctcctgt aatgtttcta cacttgccag agatctggtt aatttaagta
     9421 aaaagttcaa gattgaatat ttacagtctg tcgacatgtt tcctcagact gcacgttgtg
     9481 aagttgtcgt gaagatgacg agactcgctg actaaatgaa agaggttgtg aaaaagtctg
     9541 ccctgtatca agtaataaga acagccaaac aaaaatagct cttcatgttt tatgaatacc
     9601 gtacttgtga ccgaagagtt aacaggagga cactatttat ttaaaaaaag ggttgtgaca
     9661 tagtttttgt cacagccctt tttgattatt attggatatt cacgtctatc acttgataaa
     9721 atgcatttgt cgtatcgctg atattccata ctgctaaaat cacattatat ccttttcgat
     9781 cctgcggaag tgtgatcgtt tggttgactg tttttggtgg aacagttgct ttgtcgtcta
     9841 tttttgtgat caattcaaaa tcactaaatt tcaaaggttg attaggattc caagttggtt
     9901 tggtaatgta gtaatcccaa gtacttgtcc gatgttgtgc tgttaaattc caagtaatat
     9961 ttaatgttcc tggattaacc atgtttttat gccatctgtt agatgtctgt tcatctaaag
    10021 gctcaaagcc gctgactcct gcactagcaa tttttccatc aatgaatgta tttttggtag
    10081 cttcgatact ttgcggttcc cattgtgctc ttccgacatt ttgatttaag tttcctgctg
    10141 ctgatgttcc taggtatgca cggcttcctg gagaagtaat ataaccatgc gcaaaacctg
    10201 gaatgctaaa accgaacaac cctaaactaa ctaacccaat aaacaataac gtactaatct
    10261 ttttcatgta gaaacctcct tcatttgata accacattgt aaacgcttta ttgtattaac
    10321 acaaacatta tgcttttata attttatgtt gaagtaaaaa aggtgaaaaa agtaagatgc
    10381 agattataac agaagtagac gagaaaagta caaatagaaa acatgagaac caaatcatat
    10441 gatctttttc aaaaacatca ttcatataaa caaatgttca actttttaat aacaacaatc
    10501 atcaattttt ttcttacttc acaaactaaa tacaggtctt gctgtgagcc ttcatggtaa
    10561 actactatta tagaaaggag ttagtaaaat gaagatgata aaagatattc gtttttgggt
    10621 ttgtgttata ggaattgtca tattaggctt tttatcaggg ttgcttagcg gaaatcccgg
    10681 agaatattac tattctttgc aacttccacc atttgcacca cctagctgga tatttgggcc
    10741 gatgtggacc ttactgtata tattgatggg tatttctctt tatttgttac ttaatcacaa
    10801 caacaaaaaa cagcgaaaca atcttgtcgg tctttttgtg attcagttca tttttaattt
    10861 tatatggtct gctctatttt ttaatttaag aaatattttc attgcagcaa tcgatattac
    10921 acttttagtt attttcttgt cagtgcttat gtatcagttg tggctacatc atcgcctggc
    10981 aatgtggctc atgattcctt attatttatg ggtactattc gcaactctat tgaattattc
    11041 aatttatttt ttaaactaag cgctaaaaag agacgtcctg taatttaaca catagaaaaa
    11101 gtgccaccta agttagattt tttgtctaat ttaggtggca ctctttatta accaaactat
    11161 ttttttctag tacccacttg ttgttccata ctcattattc tggtcataac cataaccatt
    11221 ttgttcctgt ccagcgtaag gatcataact ttgagtatct tgacttggtg tatagtactg
    11281 acttgtatct tctgtttgct gataataggt attcggatct tggtactgat catatgtgtt
    11341 ttctgaatag gaagaataat cggtgtaccc ttcactattc gatccatcac cgtttgtcga
    11401 atcgccatct tccgaatcat caaagaacat cattgaagca ttctcatttt tcaaattagg
    11461 taatgtatcg cttgttttta tatttaattg tttcttcagt tcattttgga tcgaaagaag
    11521 atcatttttt cctaaaattt gatagtagat atcattgatc atttgtcctt cgccttgcaa
    11581 ctggtcttgt ttgattgttt caaacgcagg ggtgtagttc gtcgctacat caagcatgtc
    11641 atcccaatct aagtccgtcg tcacattgtt ctcaactgct tttaaaattt ttctataatt
    11701 gcttacgcca tctaaactta aaactttatt gacgattttc gtcactactt cccgctgacg
    11761 acgttgtcga ccgatatcgc cttctggatc ttcgtgtcgc attcgagaat aggctaaacc
    11821 tttttctcca ttcaatgttt gttcacctac tggtacatgg acaccatcca aagtaaagtc
    11881 aattttatta ttcactttga tgccaccgac cgcattgatc aaatcttcca tgccatccaa
    11941 attgatcgtt acataatgat caataggaat atcgagcagt tgctcaattg aatccatggc
    12001 catttcgaca ccaccaaatg cataggcatg atttaattta tctaccgttc cataacctac
    12061 gatattcgta taaatatctc ggtccaaact gatgatcgtt gatttttttt gtttcggatt
    12121 aactgttact accatcatcg tatcagaacg tccttgttcc gttcttccta atccaccggt
    12181 atctaaacct aatagcaaaa ccgaaaaagg ttctttgtca tcaatgctta ctctctcaga
    12241 acgtttggag gatattcgat tagagttttt agaaattttg tttactgttt ggctcgcttc
    12301 tcccataaat ctgattccgt atgctgataa tccggcaatc agcaaaacaa atacccctaa
    12361 caaggttaat agaacttttt gccatcgctt cataatacac ctctgtttca cattttctaa
    12421 aatattgtct catataactg ttcaatcagc aaattcactt tttaatcata agaaaacttt
    12481 aaaaaacatt tttgtgtaac gattactatt ttttaaaatt tctcaaaatt cttaactatc
    12541 ataccatacc gtgaaaaaga tcgaaagacc gaatacacgc agttcgcaat cgttttatct
    12601 ttttttacgt attttttcca gaaaaagcga acaacaaggt attttccaaa taatcgtgca
    12661 gtaaaatgat cgcacatacc tttcccatct ttttaacagt ctttgcctac cgttcagatt
    12721 atcattcgat ttcacgaaaa tttcttccta tgactggtcc ttttgttaaa cccatcttct
    12781 attcgtttta tttccagctc actgcatggc tcttaaaatg actcgaacta gtgatttcat
    12841 taccatcatc ttttaatgga tagatatgct cctcttcaaa gtaaaacgat tttcttttaa
    12901 agtaatagaa ttgacatggt aatgagtatg tatactagtg gtttcacaaa tggtctttta
    12961 ttcaacatcc aaaaactgaa atttctttaa aatccattac taacgaagaa aatgttcctt
    13021 gcttgataat tagttaggac atgtcaagtg aacaaatgca tttacttagc caaaaaatct
    13081 aaaaacttca taaatagaca aaaagacacg actctctaag aagtcgtgtc tttattcaac
    13141 aaattattat aatttagtca cttcagcagc ttgaggtccg cgtgcacctt caacaatcgt
    13201 gaattctact tcttgacctt cttctaggct cttgaagccg tctccttgaa ttgctgagaa
    13261 atgaacaaat acgtcatctc cgccgtctac tgtaataaac ccaaatcctt tttcattgtt
    13321 gaaccattta accgttccgt gttccataaa tgtatagcct ccaaaaaagt tcttgcaagt
    13381 aaccttgcaa gaacattata cccaatttag aaaacgctag caagctttcg ctcttttatt
    13441 ttccaaatta tttttaagac tgatatgacg gaggaaatgg ttattttgct gcttcgaaac
    13501 gtttgtttac ttcatcccaa ttaataacat tccagaatgc tgcaatataa tctggtcgga
    13561 catttttata tttcaaataa taagcatgtt cccaaacgtc caaacctaga attggtgtct
    13621 ttccttccat caatggagaa tcttgatttg cagtagaggt aatagctaat tttccatttt
    13681 ccattacaag ccaagcccat ccagaaccaa atcgtccagc ggctgctttt ttgaattctt
    13741 ctttaaaaga agaaaaatca ccaaaagctt cattaatcgc ttcttttatt tctcctgtag
    13801 gttcgccacc agcatttggt gccatgattt cccagaaaaa tgaatggtta gcatgtccgc
    13861 caccattgtt acgtacagct gtcttgatat ctgttggaat agcgtccata tcagataata
    13921 attcttctat tgttttttcg cctaattctg ggtatttctc aattgctgca tttaaattcg
    13981 tcacataagt attgtgatgc ttatcatgat gcagatgcat cgtttcttcg tcaatataag
    14041 gttccaatgc gtcatatgca taaggtagat ctggtaatgt gtaagtcata aaaaaattcc
    14101 tcctcaatgt tttctttata atgtctacat tacaaagagt aacaaagaga aggaaattct
    14161 tcaattgtta tgcctagtcg tctttttcac tttgacctac ttcttcttca aaaacctcag
    14221 tttctttaaa aataaacaac ttgctgaaaa tatagttcgc taggataaca ataatttgag
    14281 tgatgatttt cgccacatac tcattgctgt tcataacatt gatcaacaat accattgccc
    14341 ccatgtccaa tccgtaagaa aggatacggt agaagaagaa cttaccgcat tcaataagtg
    14401 catgtgtaaa attcggtgat tttgaatgga atacccaaag tttgttcgtt acaaaagcaa
    14461 acaatacaga acaaaaccac gaaatagaat tggataaggc catacttaaa tcaaaatatt
    14521 ggcgtgcgag agcaaaacta acaaaattta caatcgtagc caaaccacca aaaaagagat
    14581 agactagtat ctcccaatat ccttttgctt ctaaatatcc ttttaactgt cgatactgct
    14641 tcatgagcca acctacctta ttaaaaattc ttatttatca tactctatat ttcaataact
    14701 ttcatcttta tttaaaaaaa ttaatttttt ttgatccttt gcctttgtct ctgcttggat
    14761 cgtcacatgt gtaataccat attttaattt taataaagaa attatacgag gatatatctt
    14821 ttcaatctcg cttagtagct gatcttcaaa atcaatatgt ccgtcgaaaa taattatctt
    14881 ttcgctatac tgccaaatat ggacatgatg aacattcttt accccatcga ttgcttcaat
    14941 ttcttgttcc attttttcat agtcaatagc aggtgcactt tgtatcaaaa tagcggcagc
    15001 ttttttgatc accattatcg cttctatcaa tatatatatc gaaatgatca gtgtaataac
    15061 tggatcgatc cagtagatat cgaaaaaacg gatcaaaatt gctccgataa tcacacttac
    15121 cgaagacagt gtatcactta acaaatgcaa ataactagat tttatattca aactttcatc
    15181 tgcttcttgt cgtaataata atactgagaa caaattcgcg agcaatccaa taactgctac
    15241 tgttagcatc aaatgactat ttatcttttc tggtgaagtg aaccgcttga atgcttcaac
    15301 ggttaaaaac aaggataata tgatcaatat gaatgagttg atgaaagcac tcaatatttc
    15361 taaacgctgg tagccatacg tacgtttttt atttgcttct tttcgggcca ttttttgtgc
    15421 cccgtaagaa aaaataattg ccaatgtatc actaaggtta tggaaagcat ctgaaacaag
    15481 agacaaactc cctgacataa tccctccaat aaattctgat aaagtgatca ccgcattcaa
    15541 aaccactact ccaaatagtt tttttgatga tctctgtggc tgtgtaggca ctattccttc
    15601 ctccatttta tttatattgg atagtcttta gacaagaata acattttttt gatatttcac
    15661 caatcattca gatgtttccc taaagcactt gtatttcact tgatacttcg ctagaattgc
    15721 aagtgatgac actactagat gaggagtact tatgacaaca aaacaattaa ttatcagttc
    15781 ctttatacga ttcaaagacc taaaggagac gagaaatgtc ccattttgga aagccattgt
    15841 ctatctttta gttttgagta taattatggc tttgccaatc tcttttcaag tttttcaagt
    15901 cttaaacaac attcaattgg atgggcaaaa gattgctact cgcattcctg attttacaat
    15961 ccaaaacggg cagcttcaaa ccgaagaaaa agaaggattc atttaccaaa caaactccat
    16021 tatcttcaca tttgatccag agggaaaacg aacagaacag gacatctcta ctgatttgat
    16081 ggggaatttt gttagtgtcg ggatgttaaa aaacaaactt atcatagctc ttcctaatac
    16141 aggcacgact tctgctttgt tgaacaataa ccaattagaa cttccctaca ccaatgaatc
    16201 tttaaaaaac ttaacaggta aggagctccg ttctttttta agtaaagcat ctataccact
    16261 ttggataaaa gtcctgacat ttatattttc tatttatcct agttttctga atctgctgat
    16321 cactttgcta tttaccaaca ttgctgcttt tctctatgca cgctttcgac taacaaaagc
    16381 tacttttctt gattgtttaa aaacattgat ctattcaatt tcattgccta ctataattgc
    16441 aacaatcttg atggtctttc ttccttcttt tgacacaagc gccttcattg cttttgcagg
    16501 aatctttatt tttgctcaag ctgtcaaagg atgggcaaaa atatcgatca attaagaaat
    16561 aaagacaact cgttatttct acttcaatag acccttttag aggttgtgac atttttttgt
    16621 cacagcccct tttttatttg aaaaatattt ctttctcaaa aaacaagcaa ggcgcttcaa
    16681 agttcttctt gtatgcgcta cacttagagt aaagaaaggc gggaaattaa ctatgtcaga
    16741 aagaatcatt tatgcagatc gtccatttcg tgatgaattt atcgaagaaa tccatactat
    16801 agcgcctggt tatatcttta aaacagaatt acaaccagag gatctacaaa atgtagagat
    16861 cagtttgggc tggaactcag actaccaaga aaaactatta gcctcttcta ccttgaaatg
    16921 ggtccaatct atctcagctg gtgttgatca gctacccctt gagacttttt caaagaaaca
    16981 tattttactt tcaaatggta gtggcatcca cagtgaatcg attacggagc atgtcttagg
    17041 aatcatcctt gggtattctc gtggtctttt tcaagcacaa aaagcacaga gtgacatgaa
    17101 atggttaggt tcatcggtcc attaccaatc tatccaagga aaaaaaatac taatcattgg
    17161 aactggccat attggaaaaa tgattgcaaa aaaatgcaaa gcattagaca tgaactgcta
    17221 tggaatcaat acatccggtc atccagcaga aggaatggaa aagacttttt ctttaaatca
    17281 actaaaggaa gttcttcctg aagtagattt cgtagtcaat atcttacctc taacggagga
    17341 aacaactggg ctctttgatc agcatatgtt tgaacacttt gatccaaaat ctgtattcat
    17401 caatgttggc cgtggtgctt ctgttaagac acaagatctg gtgcaggctt taaataacca
    17461 gcaactttcc tttgcagcat tagacgtttt tgaggaagag cctcttccac aagatcatcc
    17521 tctttggaaa atggacaatg tactgattac ttcccacatt gcaggtttga cacctgattt
    17581 tcaaaagaaa ttaatggcta tttttttaac caatctgaaa agctactttg ccacccatga
    17641 gcttcaaacc aatcaagtaa aattgtctgc aggatattaa tagctgaaaa caatattttc
    17701 aaaagaacaa agagaaggtg acaaaacttg tgtcaccctc tcttttttta ttgtttttta
    17761 aagtgatagg ttggctcctc caggttggga tcataatcaa caagtaaatc atatccttta
    17821 aagaaccatt catctgcttc ctcgataaaa aaaagtgtcc catccatttc cactttcttt
    17881 acaggatgtt ctggctgttc aactgacatt ccaatcgaaa aaccatcatg aacctctgtt
    17941 ttgccgtaga cttttccaaa aaaacgtatt ccgtaagttt ctggcagatc aatttctgag
    18001 tcaaaccact tttgtgcttt tggcgttacc gttaattcca tcccaacaac ctactttctc
    18061 ttttctttct attgattcat cttatcgtct agaatatcca catcgcctgt ctctccaatc
    18121 accagtagat tatcattttc gcgaacatat tcatctgctg caggagaagc gataaccgtt
    18181 tgatctactc ttcgtatggc gactactgtt aagtcaaaac gttgcctgaa atttaattca
    18241 gctaatgttt tgttgaaaaa tttaggattg gagactcgga tttctgctaa agaatattta
    18301 tctgacagct ctaagtagtc tagaatattc tttgatacta agttatgtgc aatccgtatc
    18361 cccatgtctc gctcagggtg tacgacacga tctgctccga tcttctctag tacacgggca
    18421 tggtactcat tttgggcttt tgctaaaata ttcggtacgc ccatttcctt taccatcaga
    18481 gtaactaaga tactggcttg gatatcttct ccaatagcga caattacatg atcgaaattt
    18541 cttataccta atgaacgaag tgtcatctca tcctgtgcat ttgccacaac agcatgagtg
    18601 gctatattca tatattcatt gactcgatct tcattactgt caatagccag tacttcttgt
    18661 ccagcttcga tcagtgtacg gcagatgctt ccgccaaatc gtccaaggcc tacaattgca
    18721 aaattttgtt tcaccatttt cctcctttag tatcttcttt tctcagtata acaaagcctt
    18781 tccaaaaaca aaagcaagca tcattattgt aaaaaagcca agaaaaataa tagttatttt
    18841 ctcagctttt gattatcctc tttatcatcg tttttatttc accaaaccat gtttaaacgc
    18901 atagatagct gcttgagttc ggtcttctac ctctaactta gctaatatat tcgacacatg
    18961 cgttttaact gttttcagtg tgataaacaa ttcatccgcg atttcctgat tacttttccc
    19021 ttcagaaatc agcatcaaaa tttcattttc tcgattcgtt aattcttcat gcaatactgg
    19081 atcatttcgc cgactcattt tttccatcat ttttgttgtc acttcaggtt ccaatactcg
    19141 ctcgccgcgt tgcgtagccc ttatagcatc agctatttca tgtgcggtag acgtcttcaa
    19201 caaatatcct gctgctcctg cttcaattgc aggataaact ttttcatcat caataaaact
    19261 tgtgacgata atgattttgg cttttggaca atcttttaag attgcttttg ttgattcgat
    19321 gccatccatt tcttccatga ctagatccat taaaatgaca tctggtcgaa gtgccatcgc
    19381 cttttcatag ccttgacgtc cattttcagc ttctccaatc acttcaatgt cttcttggat
    19441 agataaataa gaagagacgc ctaagcgtac catttcatgg tcatctacta ataaaacttt
    19501 tatcatcttt atctatgcct ccttcatcaa agggaccttg atctccacgc tcgtaccttg
    19561 ccctttaaaa ctaatgattt ttactgttcc accaatacca gctactcgtt ctttgatatt
    19621 gttcaatcca taacttcccg ttttggtttc attcatatta aatcctgtcc cgtcgtcaat
    19681 gatacgtaat aaaagattgt tatctatttt atgcaaatag acttctaatt cattagcctt
    19741 agcatgtctt aatgtgtttg ataacaattc ttgaacgatt cggaacaagt gatcctcaat
    19801 ggaactagtt aattttacat cttctacatc ccattttagc gaaatctgga ttttattctg
    19861 caattccttc aataactgct caatgccttg ttttaaactt ttttcttcta aattgactgg
    19921 acgcagatga agaagcagcg cacgcatctc agactgggaa gcgttgatga tctctgccac
    19981 cattttcaac tgcttacgga acatttctgg tgtctcactt ttttctgctt gctccgtcaa
    20041 tgccgacatc atcatcatcg ctgcaaataa ttgctgtgaa actgaatcat gaagctcacg
    20101 agctaatcga tgcctttcta attctaaaat ctcttctttg gtttgtccat ctacatattg
    20161 aggacggcta gtcataatct gtaattcact ggatacttcg atcatttttt cttttatttt
    20221 agcaatttcc atatcaatat ctttgatgta cagatcatcc gacgcgcttg ggatcggctg
    20281 atgcaaaagt ttggattcat aattgccaga agaaagtgca cgaagctttt cttcgatttt
    20341 cccgtatttt gccttttgaa taagtgataa caatagaaat acgatcaatc ctacacctaa
    20401 tgaaattgcc atcaaatgga agataagcgg aacgtataat aaacgcgcac gcagcaattc
    20461 tccccaccaa tgactttggt tactggcata aaaataagtg aaaagtgaaa atagaataat
    20521 aaggaaagcc gcaatccccg aataaacagc tagcattgct ttggatattc ttcccatcat
    20581 attcgtatca cctcgacatc tccaaccaag gtattggtaa tgatcttcaa tctgcgagga
    20641 ttttcatcat aatcactgct gcagattttg atctgttcgt tttttaagga aaactgctct
    20701 tcttcaaaca agacatttcc tactaatgtc gcatgctcta aacgaatagc cactcccagg
    20761 ggtactaaga tccgtgttct gcctatccct tttcttacaa tcacaatatt atcatctttt
    20821 ggcaaaagtg tattacccaa atcgatgata gtatcaccag aaatgatggc aatgttgata
    20881 tcatcccatt catagacgtc gtttccaata cgttggttac caaataattg ctgtctttta
    20941 cgctcattat tatgtgtttt taattgctct gtttggacca tcatgatctg tttttttcgc
    21001 caaaaagcat tttttgtcaa atctattcct gaaatctcta cacctttcag cccgataaat
    21061 aaaacggcca atacaaccat catccataaa gcaggactgt tgactaagct aaaaaaaatg
    21121 accaagctcc ctaagatcaa ttgaaaattt tgaaatttag tacgaggata tttgcgcata
    21181 gctagatata tattgaaaat accgaatatt actaaaagca aaagtccagt attgtttacg
    21241 atttgccaaa cagcaaataa cagcagcagt gcttcgacta ccacaaaaaa acgccaagaa
    21301 ctattcatcg ctttttctcc ctcctgacac attctcattt catcatacct atttttttga
    21361 ctgttggcta taggacttta gatgtaagat cgttcagtga aacctgcaat actcaaagag
    21421 aaaagatcta gagtgcgtca tcagtaagat gaactctcta gatctttcag tcagactacg
    21481 cttgttctac tttgacgatt ttaactaaca tatcgccacc tggtgtagca atggttactt
    21541 catcattttt acgtttgcca atcaatgctt gcgcgatagg agaatcattg gaaatctttc
    21601 cagaaaacgg gtctgcttca gcacttccga caatcgtgta ctcttcttca tctccatcag
    21661 gcaactcgat gaacgtaact gttttaccga tcgatacctc atctgcatct acgccgtcat
    21721 tatcgatgat ttgtgcaaaa cggatcatat tttcaattgt tgtgattctt ccttcaacaa
    21781 atgcttgttc atctttagct gattcgtatt cggagttttc ggaaagatct ccgaaaccgc
    21841 gagcgatttt gattcgttca atgatttctc cgcgtttaac tgtttttagt tcttctaatt
    21901 ctttttctaa tttttcttta ccttctagag tcattggata aactttctct accatgtgta
    21961 acgtctcctt ttttcgataa aataccgcaa aaggtaatct tttgaggaat atagtccaaa
    22021 aaagattacc acgcttttct taaaatgtaa atgtttttct aaaaatgatc aatgactagc
    22081 ccctgttttt ctaagaatta tttacatatt tttgcactag ttccatatgt tcttcatacg
    22141 ttttagcgaa ataaacattt ccagtgctcg tatctgctac gaaataataa tagtcatttt
    22201 ctgctggttc taatactgcc ttgattgcct tttcgcttgg attgtcaaaa ggaccaggcc
    22261 catagccggt attggtatac aaattgtatg gtgaatctac agctgtatct tcatacgtca
    22321 ccaattcttt atgttctcct aatgcatata aaacagagat atctgactga agtggcatat
    22381 ttgccttgat tcggttaaag aagacttgtg caatattttt acgatcattt tcttttacgc
    22441 cttctttttc aactagagaa gccaaagtta aaacttcttg tacagtcaaa tttttctgtt
    22501 tgatagctga ataatagttt tgcatgaccg tatttgtctt gttcaccatc tcaatcacaa
    22561 gatccttaag cgaagtactc gtgtagtaat cataagtagc tgggaataag tagccttcca
    22621 aacggtattt tgtgttctca gctttagagg cactttccaa caattctggg aatttttgat
    22681 acaactcgtt aaagaaagtc tcatcattta ctaaatctaa aaattctttc ttgtctttac
    22741 ctgttacctt cgctacccgc tcagcaatct gatcgatgtc gtagccttct ggaatggcaa
    22801 ttttcccatc tgcaactttt gttggctcag atgtgccgcc ttcttgcaac tgcttgccaa
    22861 tctcatcaag agtcatatta ggcgctaact gataataacc agcttgaaag ccagttaagt
    22921 ttttaaattt tgtataataa ttgaaaacaa tcccactttt aataatattg tctttctcca
    22981 aaatttcgcc aatctgctta ttagaagagc cgtttgggat ttccacttgg actaattggt
    23041 cgtccgattt atctaaaggc ttcaacccgc tatctacata acgatatacg gtaaacccga
    23101 gaaatccgcc aataatcaat aatgtaagag cgatcactaa aatgatcttc ctcacgatct
    23161 tatcttcttt tttacgcaga tttctccgct tgtcgattat atctgctgta gctgccttac
    23221 tggcttcttt tttgtctttg cttgggtgtt gtttgtttcc tgacaaaaca actcctcctt
    23281 actatcatct tcgtaactct gtttattata catgaaattt ctactgccgt gaattatttt
    23341 accaaatatt atgtcaaaat tgtaagtggc aaatgctctt tttgaggatt acaatgaaaa
    23401 atagttaaaa atggatagaa aggatttaat atggcaaaag gaaaacatca aaaaaaacag
    23461 cagatctctc tttcttttct cgcagttttg ttgctggctg tcagcttctt ttcaacaggc
    23521 atcattacag gatggcaatt aacaaaacaa cctcaaccac aaatttataa aacggaaccc
    23581 gcacaacttg cttccaattt aacatctaat gagcagatgc ttgccagcaa aattgatcaa
    23641 ttactgcaaa aatcagatta tatcggttcg atttatgtac gcaaaaataa tcgagtgata
    23701 ttagaaaaag gatatgggta cgcaaatcta cgcataaaag aatcgaattc tccttctctt
    23761 tactatcaaa tcggttcgat ccaaaaagcg atgactgctt tacttatcct aaaacaaatt
    23821 caatctggca agataacttt tgacacaaag ctatctgaat tttatcctca gattcctgga
    23881 agtcagcaaa tctcaatcaa aaatatgctt tacatgcgct ctggtcttca tcgaaccgct
    23941 tctccaaaaa aacctatgtc agatagtgag atcattcagt ttgcccttca tcatttgaaa
    24001 tttactggtt atgatacgta tcattatgaa ccattaaatt atacattgct tacaggggta
    24061 ttgatcaaac taatgaatca gccttatgaa actcttttaa aaaaagaaat cattcggcca
    24121 ctccatctag aacatacaga tttttatgaa aatgtaaaaa attcccctca gcatgctgta
    24181 tcttaccaaa tgtctgcaac tgacgattat tcaaaagcat tggtcgagcc tgaaacagac
    24241 atccgaaatg aattaggcac aggaaatata agtatgtctg tttatgactt gaacaaattc
    24301 tttaccagtg ttctgtctgg cgatattata ccaaaagaac tacttttctc attgtggcaa
    24361 aataatggtg ataaacatcc ttacagcggc ggtgtttaca gtggaaatga ttatatcctt
    24421 gctcagggaa atatcaatcg attccatgca gtagcggcga tgaaaaaaga cacaaaagat
    24481 gcaatcgtca tggaaagtaa tatccaatct gataaaaaca tcaaattgcc ggccactgat
    24541 ttaagaaatc agatttacga actgatggaa ggtgttaatt taaaaagcta agtcgagaca
    24601 aaaaaaccag caggatgctg gttttttgtt tcaatcgatt tctgtcttta aataacgttc
    24661 cattccgttc aatatatcaa atttgggttg ataacctaaa gaacggatct ttgaaatatc
    24721 cgctaaagaa tcacgaatat cccctgaacg ctccgcttca tatttaagcg ctagctctgt
    24781 tcctaagatt tgatcaattg aatgaatcaa ttcaagtagc gtagtgcttt ttcctgtacc
    24841 gacattgaat tgctgtccta aagctttttc ttccttagca acaagtaaaa gtgcttgtat
    24901 aacatcttct atataaacga agtctctaga ttggctacca tcaccaaata aagtaaattc
    24961 tgttttttct cctgccaatt gttttttgta tcggtccact agaatcgaaa taactccgct
    25021 atatggagag ttaggatttt gatttggacc ataaacgtta aaaaatcgga cagcactagt
    25081 cggaacatca tataaatgac agtaatccaa aacatattgt tctgatgcaa acttatcgat
    25141 ggcatatggt gttaaaggac ggatgaccga ttcttctttt tttggcaacg ttggttcatc
    25201 gccataaact gcagctgatg aactaaatac caatcgtttt aaaccagatt gatattttcg
    25261 taccaattca agcaataaaa gcgcactgtc aaaatttaca cgatgagttt ctagaggacg
    25321 ttctacagaa tctgccacac tagctacagc agctaaatga aaaatatagg caaactgata
    25381 ctgtttcatg attctttcca tcaattgagg atctgataca tccccctcaa tgaaagtcac
    25441 ttgtttctcc atatccaagt tttctttttt tcccattgat aaatcgtcga ctactacgat
    25501 tttgttttct tttcccaaat aattcgctag cgttgaaccg ataaaaccag ctccaccagt
    25561 aatcaatata gtatccatca aattcactcc aattatgcat tctcatactt aataaagtta
    25621 gtttaccatt tttatattgt aaaaactata aaatttgttg aagttgggat aactagtttt
    25681 cttttctact ttatatacct aaaaat
//
LOCUS       DADVXM010000033        25585 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.034, whole genome shotgun sequence.
ACCESSION   DADVXM010000033 DADVXM010000000
VERSION     DADVXM010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.034"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            167..2227
                     /locus_tag="KB927_001441"
     CDS             167..2227
                     /locus_tag="KB927_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBB6840366.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSNVYEKDYSQFEGKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2310..2879
                     /locus_tag="KB927_001442"
     CDS             2310..2879
                     /locus_tag="KB927_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6840367.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(3054..3860)
                     /locus_tag="KB927_001443"
     CDS             complement(3054..3860)
                     /locus_tag="KB927_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840368.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3998..5512
                     /locus_tag="KB927_001444"
     CDS             3998..5512
                     /locus_tag="KB927_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBB6840369.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5915..6898)
                     /locus_tag="KB927_001445"
     CDS             complement(5915..6898)
                     /locus_tag="KB927_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBB6840370.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6903..7550)
                     /locus_tag="KB927_001446"
     CDS             complement(6903..7550)
                     /locus_tag="KB927_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6840371.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7635..8267)
                     /locus_tag="KB927_001447"
     CDS             complement(7635..8267)
                     /locus_tag="KB927_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6840372.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8283..8834)
                     /gene="coaC"
                     /locus_tag="KB927_001448"
     CDS             complement(8283..8834)
                     /gene="coaC"
                     /locus_tag="KB927_001448"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBB6840373.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNTITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8831..9568)
                     /locus_tag="KB927_001449"
     CDS             complement(8831..9568)
                     /locus_tag="KB927_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBB6840374.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9565..10554)
                     /locus_tag="KB927_001450"
     CDS             complement(9565..10554)
                     /locus_tag="KB927_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBB6840375.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10812..11354
                     /locus_tag="KB927_001451"
     CDS             10812..11354
                     /locus_tag="KB927_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6840376.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11371..12456
                     /locus_tag="KB927_001452"
     CDS             11371..12456
                     /locus_tag="KB927_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840377.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12468..13274
                     /locus_tag="KB927_001453"
     CDS             12468..13274
                     /locus_tag="KB927_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6840378.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13275..14102
                     /locus_tag="KB927_001454"
     CDS             13275..14102
                     /locus_tag="KB927_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6840379.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14099..15172
                     /locus_tag="KB927_001455"
     CDS             14099..15172
                     /locus_tag="KB927_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6840380.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            15600..18296
                     /locus_tag="KB927_001456"
     CDS             15600..18296
                     /locus_tag="KB927_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6840381.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            18373..18861
                     /locus_tag="KB927_001457"
     CDS             18373..18861
                     /locus_tag="KB927_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6840382.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            18873..19367
                     /locus_tag="KB927_001458"
     CDS             18873..19367
                     /locus_tag="KB927_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6840383.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            19388..20197
                     /locus_tag="KB927_001459"
     CDS             19388..20197
                     /locus_tag="KB927_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6840384.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            20194..21015
                     /locus_tag="KB927_001460"
     CDS             20194..21015
                     /locus_tag="KB927_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6840385.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            21066..23165
                     /locus_tag="KB927_001461"
     CDS             21066..23165
                     /locus_tag="KB927_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBB6840386.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            23162..24280
                     /locus_tag="KB927_001462"
     CDS             23162..24280
                     /locus_tag="KB927_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBB6840387.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            24319..25197
                     /locus_tag="KB927_001463"
     CDS             24319..25197
                     /locus_tag="KB927_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6840388.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            25388..25540
                     /locus_tag="KB927_001464"
     CDS             25388..25540
                     /locus_tag="KB927_001464"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBB6840389.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
BASE COUNT         8087 a         4453 c         5412 g         7633 t
ORIGIN      
        1 attaaaaagt acataagtta ttattccgat tttcttgaaa caataaaaaa tcaaaaaaaa
       61 tactctccta atagtccatc ttcttttgat tttatttata taatgaaatc atcttatgaa
      121 aattactact tcatgtttag acaagagtag ggaggactaa gaataaatgt gttcaaaaag
      181 acgttcaaaa caactaaata aacacgcttg tcgtttagat aaggaacggt cgtgttctga
      241 aaaacactac gttaagttta tgatgcgcac gatgctgatc agtttatctg taggtgtcta
      301 tatgcatgta cccgttcagg caacgacaca aaccatcaag gtcgtacgta cctctgtttc
      361 tgagaccact gattccccta tcactattac tcatactttc actgatgcaa atggaaaaca
      421 gctacttcct gcattgactt cctataataa agtcagttat cctccaacga taaaccacta
      481 ctggttaatt cctaacaaaa cattatggac atcggaaacc ggaagcagtg tgccgctttc
      541 tatcttttcc gatatgactg atcctacaaa aggtgatcag ttaaaacaga tcactgatat
      601 tttgaatcat gctttgacag atataaagga cggtggaagc gcacaagttt ctaatgtata
      661 tgaaaaagat tattcacagt ttgaaggaaa gaaaatcgat gttctggcag ggacaaaagt
      721 ttcgatatct gatctggtag aaaggctgaa gaacgcagat ggaacacaag gagatatgtc
      781 caaagtaatt tcaaacaatg ggaatatcgt ggatacgact aatacaggaa catctactat
      841 ttccttgtcc tattttgatc caattgcttt aaaaacaatg actgcatctg ctgtgatcca
      901 tgttcgtgct gatcaaacag ctatcaaagg aaaagatctt cacttaagaa caggagagag
      961 ttacgcccct aaagatcttg ttgaatatgt aacaaaaagc gatggaactt caggaaataa
     1021 agaagaaatc aaaatgaacg ggacagtaga tactacaact ccgggagaat atcccgttgt
     1081 attaacttat atagactcga aaacatcaaa tgtggcagaa acaacagctg tagtttatgt
     1141 agaagcatct gctgcttcat cgactgtcat cactcatttt atagatagtc aaacaaataa
     1201 agaacttcaa gcagaaacac atatgagtag tgtaaatcgt attcctgatt tgcgcctacc
     1261 tgctgaattt tctgatcgag tgccaaatat agatttatcg acttatgaac aaaatgggaa
     1321 agtcacttct atttctgatt ggatgcaagc aaacggatta gacagaaaaa gtcactggtc
     1381 ggagatcctt gaagtacttc actcagaact gatgaataat aggaagcaat caggagggga
     1441 aattaccttt acttatgttt atataccaga caatcgttca ttagaaggtc atgatcttat
     1501 tgttcatcca aacgaaaaaa taaacaaaga agagttgatc caatcagcaa caaattcctt
     1561 aggtaaaccc gtaccgttaa aggatgtatc ggttacaatc aatgaagtac cattggagga
     1621 tggttatttg accaaacaaa caggtgattt tacgattatg tatagttatc atgacccgta
     1681 ttcactccaa gaactccatg ctcagtcact attacatgtt ttaccattaa acaaacagat
     1741 agatcaaaaa gaacaaaaaa gacaagaaga aagcttgtca gaaaaaaaac aacaaatggc
     1801 tcatgcagtt tctccaacag ggaaagtaaa acaaacaaga agcctagagt tagcaagaat
     1861 atctagaaaa atctcagaat ctaataaaac gataaggcaa gaagctcatt tggccccaca
     1921 agtttctgga ttggaaaatg aaattttaga gcctaaaata aaacaacaat cagaaaaaga
     1981 atttgttgct aaacagtcgg aagatcagaa ggaatcagat gaccagaagg aaacgaagaa
     2041 aaaacgcttg tcaactattg attccaccga tgagcatctg cagccgcaag taccacttcc
     2101 tagtccggga acacccgcac ctggtggagg tattccttct tctgctttag gagatttcat
     2161 gcgaggtatg gcaggaacat gggtatacgc taatcgaaat gaatttgacg cagatgactg
     2221 gttctgattt atatctctat ctgttatagt caaataagta gctgagtcat atgttatttg
     2281 gcataatgga gacgaggagg gatagaaaaa tgttagataa aacgttacct tacgcagaaa
     2341 tctggatgac aagaccactt caacaaaatg ttccaatcac gcctttagcg gaaggttttg
     2401 aatttcgatt ttatcaaaaa gaagatgaat ctgcttgggc ggagattgag acttccgttg
     2461 gggaatttca aacgacagat gaagcacttg agtattttca acaaaacttt gctccttatc
     2521 ctgaagaact tgaaagaagg atgttttttg tagagacaaa aaaaggagaa aaagtagcaa
     2581 cctgtaccgc ttggcgaaaa aaatcaagag agcaagtgta tccggttttt cattggttag
     2641 cagtgaaacc agattaccaa ggaaaagggc tcgcaaaagc attgactgcc agagtcttgc
     2701 aagaatttcc taccctccat acggacggac caatctatct tcacacacag acatggagcc
     2761 atcaggcgat tgctctttat aaaaaaatgg gttttacttt tattgctgaa aatctagacg
     2821 gcacacctaa tccagattat gaaaaagtta tgcaggtttt aagtaaatta gataaataac
     2881 gaaatggtga aataagtcct cagtattggg ataaaaaacg aaatagtcat tcctcatatc
     2941 ttactttttt gagttaatac tatcggataa ctaatggcat gccatacatt caaaaaagaa
     3001 ggggcagtga caaaagtatt gtcactgccc cttctcttgt tttttagcat gttttatcgt
     3061 ttgatttttt taggaataaa attcttgatg aacgtaaatt tttggtaatc gtttcgacta
     3121 tagaggtaac caaatacact gaaaacaact gctccaataa aattaacaaa taaatccttc
     3181 atagtatcca tgattcccac gtctaagtaa ccattttgga tgattgtttt atctgtttta
     3241 ccatctgcat tttgactttc aatgattgtc cgagtgatat ctggaacatg atagacagtg
     3301 tttccgtctt tacttaactc cacactattg atttgctgga tgatcgtatc tttttgcata
     3361 tcgaattgca gtaatttatc tgctgaaaat tccacaaact cccacataac accaactgtc
     3421 atcgaaaaac agaaggaaac aactgctagt aataaaggag tcaagttcat ggtttttgta
     3481 tttttattga gcaaataaac aagggaaaag ccgacacccc cagctaaaaa tccgctgaat
     3541 gcatgtagaa aagtatccca cattgaaaaa tagccataaa aatcacttaa ctctcctaaa
     3601 actgttgaac taaaaataaa agataacaaa atgatttcta gcatatttgg aatctgtatc
     3661 tttaatatct tttccagaaa ataagggatt tcaaataaaa ttaatgtcag taataaaagc
     3721 attgtatttc cccagtgttg gttccagacc tgatccacta gcataataac gacgatgata
     3781 cgtaataaaa tatagattcc gtttgtgatt ctacctgcag tttttgtact gttcgtaaaa
     3841 aaggttttca aatgattcat aaaataactc cttcatgtat atccttaatt atactaagaa
     3901 gcgtgtgttt accaaagcta tatgacttaa agaaaaacag agttgatatt gtgaaaaaaa
     3961 tcacttaata tagtataagg agaaaagggg gatacaaatg aaaaaattag ttgctggttt
     4021 attaacagcc gttgcacttc ttgctatgag cgcatgcggc gcagatcaga aaaatacagc
     4081 gcagacaagt tctagtacga aggaatctgc cgaagtatca tcaggcgctt ctgaacaagt
     4141 atatacagat ccaaaagaaa tgaaagaatc ttatgatgtc gtgattattg gagctggtgg
     4201 tgcagggatg gcagcagcta tcgaagcaaa agatgctggg ttgaatccag taattttgga
     4261 aaagatgcct gttgccggag gaaacacatc taaatcatca agcggtatga atgcttcaga
     4321 aacaaaattt caaaaagaag aaggaatcaa agactcgaat gatgccttct atgaagaaac
     4381 gctaaaaggt ggtggaggaa cgaatgataa agaaatgctt cgatactttg tcgatcactc
     4441 tgctgatgcg gtcgattggc tagatcaaaa cggtatcaaa ctggacaact taacgatcac
     4501 tggagggatg agtgaaaaga ggacacatcg tccgtctgat ggctcggcta ttggtggata
     4561 cttagtggag gggttattga ataacgtcca tgagcgggaa atccctattt ttgtcaacgc
     4621 agatgtgaca gacattaaga aaaatgggga aacggtcaat gaagtgactg tacatgttca
     4681 aggagaagaa ccaaaagagg tcaccggaaa agcaatcgta gttaccacag gcggttttgg
     4741 tgccagcaaa gaatttattg aaaaatatcg tcccgattta gctgattata ttacgacaaa
     4801 tcaagaagga tcaactggag atggtatcac catgattgaa aaattaggtg gacaaaccgt
     4861 tgatatggat aaaatacaaa ttcatccaac tgtgcagcag gatgaggggg tcttgattgg
     4921 tgaggttgtt cgcggagaag gagcaatctt ggtcgatcaa gaggggaaaa gatttgtcaa
     4981 tgaaatggat acaagggata aagtatctgc agcaattaca gcattgcctg aaaaatcagc
     5041 ttatttgatt tttgaccaag gcgtgcgtga tcgtgccaca gctattgaat tttatgacca
     5101 aaaaggatat gtcacaactg gaaagacaat ggaagaatta gcagaaaaaa tcgatttacc
     5161 aaaagaaaca ctagcaaaaa cagttgatgg atggaatacg gatgttgcgg agaaaaaaga
     5221 tgctcaattc aaccgtgcca cagccatgga acatgactta tcgtctccga attattatgc
     5281 gatcaaaatc gcaccaggaa tccattacac gatgggcggt gtgaaaatca atacgaacac
     5341 tgaagtatta gataaagaaa accagccaat tagggggtta tatgctgctg gtgaagtcac
     5401 aggtggctta catggaaaca accggatcgg tggaaattca gttgcggaga tcattatttt
     5461 tgggcgacaa gcgggcatac aagcagctcg atttgcttcg gaaaatgaat gaaatagaac
     5521 gtaaataaaa agaggttgtg aaatcagcgt tttgagctaa taccgagggt cagctgattg
     5581 aacactgttt agtgaagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
     5641 aagtaaaaac agcttcttat gtttttaact tggttggact tattaccgca gatgcaagct
     5701 tttgaacacc gtttattcgg aaaaagagcg tgggacaaaa gtaaagaaca cttttgtctc
     5761 acgctctaaa cacgtataaa cggcggaagc agaagaaatt ccttcggaaa taagctgaaa
     5821 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
     5881 ttctgtccca gcctcttttt tgatcagcat gattttattc agttatcttc aaaatgattt
     5941 ttccgatgtt tttgtttgct tccatatatt catgcgcttg tttgactgcg ctgaattgga
     6001 atgtacggtc aatgattggc cgaatcttgc cattttctag aaaaggccca gctttttgca
     6061 taaaagtttg tgcgagctct gctttatact gatcacttct aggtgtcaat aatgtaccaa
     6121 gcagttggac acgtttccca atcaatacac caaggtctat ctcaggcacg atggtcccac
     6181 ctagcatacc aatcaagacc caacgtccat caacggctat agaagctaaa ttcttttccc
     6241 agtaagaagc gccgatgaaa tccaaaataa catcgactcc ccgaccttca gtgatttttc
     6301 gtacctcttc ttgaaagtct tgttttttat agttgatcaa ttcatctgca ccaagttctt
     6361 tacaaaaggc gagtttttct tctgatcctg cagtaacgat gattttcgcg tgagaaagct
     6421 gtctagctaa ttggatcgct gctgttccca caccacttgc tcctgcatgg atcaagacag
     6481 tttcgccttc ttgtaatttt ccaagccagt aaagtgtttg ataagcagtc aaaaaaactt
     6541 ctgagattcc agcagcagaa acatagtcta gcgtatcagg gagaaggatt gcacgatcgg
     6601 caggcatcac agcatattcg gcataaccac ctagattgac taatccgtat acttttgtcc
     6661 caggagtaaa agtggagata tcacttttat tctcaactac ctctccagct acttcgactc
     6721 ccaaaatagg gtagggaggt ttcaaagaga ctgattctct tttcataata tctgttcgat
     6781 tgacagctgc tgtatggact ttgatcagta attcgccttg ttttggttta ggaacaggca
     6841 cttcaatttg ttctaataca tctacagaac caggatgctt gattgaaatg gcacgcatgg
     6901 atctattcct cctttgccca ttcttggaat gctgtattca actctttgct accttcagaa
     6961 agtactagag tcgtacgaga aatatccgtt tcttccacta gagcggcaag tacagcagca
     7021 actgtagagc gagtgatcgt ttttgatgcc ttctcattag gcttagttaa ttgaatggaa
     7081 gtaacttctt catcgttagt caatgtgact ggttgaagaa tgacaaaatc taagttagtt
     7141 cgtttcagcc attcatctgc ataatgttta gtaatataat aatctgtcat ggactcaggc
     7201 cattttgctg gttcatctgc ataaacagca ctgaccatca gatagcgaga gacatgcgca
     7261 ttttcagctg cgatcactgt tttgattgcg ccatccaagt ctacttgcag aagattcttt
     7321 ccttgagagc cggcagcaaa aatcaataca tcgatgcctt tgaatgcttc ggtcattttt
     7381 tccacggacc aagttaaatc aaaagagaca tacgaaacat tctctttttt tactaatgtt
     7441 tgggaagcaa catctctcac ccctgcaaaa atttcatggg aacttggagc taaatctttt
     7501 atcaggtgtc ggccaatttg tccgtttgca cctacaacaa aaattttcat ttggatcatc
     7561 ctttcgacgt caaatctttc cattcaatag taacaccaaa agagaaaaaa atcagagatc
     7621 ggctacgatg actatcagtt agtaagagaa gggtgcttga agtatcttaa caagacattg
     7681 catactgctg cagtcgcaag acctgcgacg attccttcag gtataccact tgtaaaaata
     7741 accgctagaa tagctgaata aacagcattt aaatttgttc cgatgacttt ggcataatct
     7801 tgctggaata aaaagtagat catattcatc actaaaatcg tattggtcaa tgaaccggaa
     7861 agtccagcta agaataaaga aacggaatct gctttttgtt tcattagttt gcgcagacct
     7921 ttataaacga aataaggaac caccccaatc aagatgcgag gaataaacgc gatcagcaag
     7981 gctttccagc ttccatgttc tgttccgatg actgggataa acggagaaaa gacaaaagac
     8041 aaaggtgttt ggataactgt gctacggatc atgctgatca gtccaaatgt accgccaaga
     8101 aaagcaccta gtcttggtcc taaaacgatc gaagcaatga ttacaggaat atgcatggtt
     8161 gttgcattga ttggaccgat agggataaaa cctaaaggcg taacagctaa taaaatcaaa
     8221 atagctaaaa acatcgcagt taatgtaaag ttttttgtat ttttcataag tactcctttt
     8281 ttctaagcat ttctttcatt aagagtcagc atgacctgtt cgatgatcgt ctgaatatca
     8341 gctaaggcac cttttccaaa atctccacaa gctaaaagag attctcttgg ttcaatttcc
     8401 tgatagccga cagatctcaa tgtttccaga ttacgctgag tgatcgtgtt ttgatacata
     8461 ttcgtgttca tggcaggggc aatcaatttt ggtgttccca ctggaagcgc cattgcgact
     8521 gttgaaagaa gatcgtctgc aatgccattt gctagcttgc cgataatgtt tgctgtagca
     8581 ggcgcgatga gaaacaagtc agcttgtttt gctagttcga tatgattgat tacctgcgga
     8641 tttgattctt gcatgacgtc tgtatggact gcgcgcttcg acagagattg caaggttaat
     8701 ggcgtgataa aatgtgtgct gcttttagac ataatcacat ctacctgggc acctaatttg
     8761 acgaattgac ttgtaagatc agcgcttttg taagcagaaa tacttccagt aacgcctagt
     8821 aagatctttt tcattttgat tcctccagtc taattttctc agtaatcaat gcagcaatct
     8881 cagatttact ttgagcttct tccactgttc catctttaga taagagatag ccgtggtgtg
     8941 tctcgccatg gatttccgtc aaatcatttg cgaaaataaa atcagttttg ttatttatca
     9001 gactattttt tgcgactgcc agaagagatt cctttggtac atctactaat agtttgaaac
     9061 caatgatttt tgcttttggc tgccattcac gtagataaga aatgattttt ggtgttttct
     9121 tcaaaacgag cacaagatgc tcggtgttag aagagatctt tgaaacagtg gtatctgtct
     9181 gttcattttc cgcaaaccaa ttgtccagtt cttcttgcgt tgaagaagtg ggtaggtttt
     9241 ttgccagctg ttcttctgaa aaactaaaag caggagtaaa atcactgact gccatactgt
     9301 ggataatcgc atcgtagtgt tcttttttcg ttagttcttc taattgtaaa aataagtcca
     9361 gtgcagattc gatcgtataa atcgttatat tggagtgtct tttcggtttc agtgcttgtt
     9421 tcgtagtcac gtaatcgatt gtggtatccg gattggcagc taaataatca gctaatgctt
     9481 gccctaatcg tcctgtcgaa tgatttgtaa tagcacgtac ttgatcgatt ttttcagtcg
     9541 ttcctccagc tgtgattaga atcttcattt atggtcacct acatttacta gtgttcttcc
     9601 ttggtgtgtt ccagcaagta gtttagatgc tgtttcaggc aattgatcca gagtaatctc
     9661 ttggacgacc agttcatctg caatctgcaa atccgccatc tgttgccata aagaaagacg
     9721 ttgatctatt ggtacattga cagaatcaat tccaatcaac tggatgtttc gcagaataaa
     9781 aggcaagaca gtcgcgttta gtttgattcc cccagcattg ccacataaag ctactgcacc
     9841 gttataagag atcaatggaa gaagactgct tagctgctcg ccacctactg tgtcgatgac
     9901 atagtcgatt tgctgttttc ctaaagcttt tgttgtctct ggcagaaatt catcaggtcg
     9961 tacgacttgc aaagcaccta gactttttag ccatgtgaca gactcttctt ttctggaaaa
    10021 ggcaatgatt gactggaatc ctagtttatg taacagggct atcgctgtac tgcctacacc
    10081 gccagaagca ccagtaacga caactttttt atcggaggtc ataccttgac ggattaaagc
    10141 gttcacacac aacatagcag taaaccctgc tgtaccaagg atcatcgctt gacgcagcgt
    10201 catatttttt ggtagaggaa ctaaccagtc tcctggtact ttttgatatt ggctataacc
    10261 gcctggatgg gtgacgccaa gcccaaaacc agtagcaagt acaagatctt cttttgaaaa
    10321 acgtggattg ttactttgga cgacagttcc ggataaatca atccctggag tcatcggata
    10381 tgttcgtatc acctgaccag actcgctcat tgccaatgca tctttataat tgacatcaga
    10441 ataggcaatt tttaccaaga cttcattttc agccaactca gtaaatggca gatcactgat
    10501 tgctgtatgg aaaacaggtt cctttattac ctgaaaagat cgaaaagcgt tcattcgtga
    10561 gacactcctt ttaaaatttt cttttatcat accataaagc ctactctttt attcttgttc
    10621 ttccgtaaat ttagacaaaa attaggtgaa aaataaagaa tcaaacaact agaatttatt
    10681 ccaaaagata aagaaatatt cagcaaaaaa aattttacaa agggttgcct ttttcaataa
    10741 atttcgtata ctaatacgag tggtagtaaa caggaagttt actattagaa aacttcgatt
    10801 cggaggaaat tatggaaatt ggtgagaagt taagaaattt gcgcatccaa aagaatttga
    10861 cacaagaaga actaggcgaa cgcacagatt tgtcaaaagg gtatatttcc cagttggaac
    10921 gagatttaag ttcaccatca atggaaacat tcttttctat tcttgaagtc ttaggtgtga
    10981 ctccagaaga attttttcat caagaagcag cgaatctgca agtggtttat tcaaaagaag
    11041 atcatacggt ttatttcgat gaagaaaacg ggtatgaatt ggaatggctc gtggctgatt
    11101 cgaatgaaaa agaaatggag cctgtcttgc tgacttttga aggtgcagga gaatataaga
    11161 cgtttgaacc ttcattatct gaaacgttta tttttgtatt agaaggggaa ttagagttaa
    11221 gcttaggaga gacggtctat gtggcaaaag caggacagtc gatctattat caagcgacaa
    11281 aacaacatca attaaggaat catctcaaaa aacgaacaaa agtattgatt gttgcaacgc
    11341 aatcatattt gtaatatagg gggtaaaaac gtggggaaac caatcatttc atttgatcaa
    11401 gtagtgaaac gctatgatga tgaaacagta ttaaaaaaag taagttttga gatcgaacaa
    11461 ggaaaatttt atacactgct tggtccttcc ggctgtggta aaacaacgat cctacgtatt
    11521 atagctggat tcaccgaagc tacagaaggg gacatctatt ttgaagggaa acggttgaat
    11581 gatttgccag ctaataagcg acaagtaaat acagtcttcc aagattatgc actttttcct
    11641 catatgaatg tttttgataa cgttgctttt ggattgaaga tcaagaaaat gtccaaatca
    11701 gatatcgaaa agaaggtaaa agatgctttg cgtatggtcc agcttcctgg atacgaaaaa
    11761 cgggagatta gtgaaatgtc tggtggtcaa agacagcgtg tagcgattgc acgagcaatt
    11821 gtaaatgaac cgaaagtatt gctattagat gaaccgttat cggcgcttga tttgaaacta
    11881 cgtacagata tgcagtatga actgcgggat ctgcaacaac gattaggaat cacgtttatt
    11941 tttgttactc atgaccaaga agaagcgttg gcaatgagtg atgagatttt tgtcatgaat
    12001 aaagggaaaa tcgtccaaag tggtacaccc gtagatattt atgatgagcc aatcaatcat
    12061 ttcgttgctg attttgttgg ggagagcaat atcgtggacg gtgtaatgat cgaagataat
    12121 ctagttgagt ttgttggtaa gcaatttgaa tgtgtcgatg gcgggatgcg tctaaatgaa
    12181 ccagttgaag ttgttttacg cccagaggat ttgacgatca cgacaccaga taaaggaaaa
    12241 ctagtcgtaa cggtcgatac tcagctgttt cgtggtgtcc attatgaaat catctgttat
    12301 gatgaacagc aaaatgaatg gatggtccat tcaacgaaaa aagctaaaga aggaagcaaa
    12361 gtaggattgg cctttgagcc agaagatatc catgtcatgc gtttcaacga gtctgaagaa
    12421 gaattcgatg cacgtcttga cagctacgaa gaataggggg gacaagaatg aaaacaatgc
    12481 gcaggatcta ttccgtccct tatattttgt ggctcggttt attcgtgatc gcgcctgtat
    12541 taatgatcat ttatcaatct ttttttgata tgaatgggca attcacgctg aataattatc
    12601 tatcttattt tacgtcgggg acatcgcttt ctatgacgat caattctgta tggtatgcat
    12661 ttttgatcac gtttttcacg ctgatcatca gttacccgac tgcttatttt ttaacaaaac
    12721 tgaagcacaa gcaattatgg ctgatgctga ttattttgcc tacatgggtg aatctgctgc
    12781 ttaaagctta cgcatttatt gggattttca gtgtgcacgg cagcgtgaat catttctttg
    12841 attttatcgg gatcgggccg aaacagatat tattcacaga cttcagtttt ctgttcgtgg
    12901 caacgtatat cgagattcca tttatgatta tgccaatttt caatgcattg gaagagatga
    12961 atccttcttt gatcagtgct agtagagatt taggcgcgaa tagctttgag accttccgac
    13021 gagtgatttt tccgttatca ttaaatggtg tgaaaagtgg tgtccaagca gtatttattc
    13081 cttctctttc tttattcatg ctgactcgtc tgattggcgg aaatcgggtg atcactttag
    13141 gaacggctat cgaacagcat ttcttggtta cacaaaactg ggggatgggt tctacaatcg
    13201 gtgtgatttt aatcattgct atgttcatcg tgatgctcct gacaggcgag aagaaaaaag
    13261 gaggtcgctc ataaatgaaa aaatttaaat ggtcgtatct ttatttaggg atcgtctttt
    13321 tattcttata tgcaccgatc ttctatctga ttttttattc cttcaatgaa ggaggaacga
    13381 tgaacagctt tacaggattt acttgggaaa attatgaagc tgtttttgaa gatacacgtt
    13441 tgatcattat cgtattgaat acgttcatgc tggctttctt atctgcattg atcgccacga
    13501 tcatcgggac atttggggct atgggaatct attacacgaa aaaacgacgt gcacggacag
    13561 cgttgttgag catgaataac atcttattag tctctcctga tgttattatc ggtgctagtt
    13621 tcttgatttt ctttacacta ctaggattcg gattaggttt tcagagtgta ttgctttccc
    13681 atattgcttt cagcattcca atcgtcgtct tgatggtctt gccaaaattg caggaaatga
    13741 acgattcaat ggtcgatgcg gctagagacc ttggtgctaa taatttccaa gtagtcaaaa
    13801 atatcatttt gccttatctt tctccaggaa tcatagctgg atattttatg gcatttacct
    13861 attctcttga tgattttgcg gttacatttt tcgtcacagg aaatggcttt acgacgctct
    13921 cagtagagat ctattctcgt gcaagacaag gaatcagttt agaaatcaat gcgctaagtg
    13981 cgttagtttt cttgttctcc atgatattgg tcattggata ctactttatt agtaaagaaa
    14041 accgtccaaa acggctgaag aaaaacagaa gagtacgcga gggggtggca cggctgcgat
    14101 gaaaaaatta caatctctgt ttttaggtat tctcatcatt attgcggtgc tgctgcttgg
    14161 tgttcgtcaa cttgaaaaaa caagtggcat gagtggagca aaggtactta ccatctataa
    14221 ctggggagat tatatcgatc ctagtttgat cacgaaattt gaaaaagaat atggatacaa
    14281 agtgaattat gaaacatttg attctaatga agcgatgttc acaaaaatcc agcaaggtgg
    14341 gacaaactac gacatcgcta taccaagtga atatatgatc caaaaaatga tcaaagaaaa
    14401 actagtactt ccattagatc attcgaagat caaaggatta aataatattg atccacgatt
    14461 tttagacttg gattttgatc cagataatca gtattcgatt ccatattttt ggggaacttt
    14521 agggatcgta tataacgata aattctttga tgcaaatcaa attaagcatt gggatgattt
    14581 gtggaagccg gaattaaaag acagtttgat gctgattgac ggtgcacgag aagttatggg
    14641 gctttctttg aatagtttag gctattcttt gaatagtaag aatatggcac agctgacaga
    14701 agcagcaaat aaattgaatc atttaacacc aaatgtcaaa gcaatcgtgg cagatgagat
    14761 caaaatgtat atgatcaatg aagaagcctc cgtggcagtg acattttctg gcgaagctgc
    14821 cgatatgatg tgggaaaatg aacatttaca ttatgtgatc ccaccagaag gatccaatct
    14881 ttggtttgat aatatcgtta tgccaaaaac cgtgaaaaat aaagaaggtg cctatgattt
    14941 catcaacttt atgctagaac cggaaaatgc ggcacaaaat gcagagtata ttggttattc
    15001 tacaccaaat gaagaagcaa aagcgttatt gccaaaagac atttcgtcgg acgaacaatt
    15061 ctatccatct gatgacacga tctcccatct tgaagtctac aaagatctag gatcgaaata
    15121 cctaggcatc tataatgacc tattcttaga attcaagatg tataggagat aatggcaaaa
    15181 ctcagtaaga atggggactt atcaacgttc taaagagcta aaaatcgtcc tttttctatc
    15241 tgagttttcc aatcttctac caaaagcgga tgaaacgccg ctttttttgt gttattttat
    15301 tttttctacc acgtttttct accagagaaa agtggacaaa accattgtaa aatagggccc
    15361 gagacgggct agtaaatcta agattgaaaa agttacagaa ggataaagta attggaaact
    15421 atgcaaatat acttaaccct tctgtaatct attaataaaa ctaatatatg aatccagttc
    15481 aatatttgta gctatgaaaa aacataaaaa tcatattaga taaaaactaa attggtagat
    15541 aaattatttt gtcagatatc tgaggcaaat attcgactat ttgtgtttca aagtaaaaat
    15601 tggaatacaa atatagaata gacatattgc agccgatagt ttattatgct tttagacaca
    15661 ttaaactgga ggaaaaaatg aaaaagagcg ctaaagatcg agtttttgat gagctgatac
    15721 gactaacagg gaatatgtct tctgtcactg ccgagaaaat ttcgaagaat ctaggtatct
    15781 ctcgtcagaa tgccagccat tatttgacga gattagtgga agataaaaag gtcgagaaat
    15841 taccgggaaa gcctgttttg tggaagcctt tagatgaata tgcggttgta gataatacgg
    15901 agcaaataaa cgaagccttt cattctgtag ttggtcatga cggaagtctg agagaggtca
    15961 ttcaaaaatg tatagccgct gtcaaatatc cgcctaacgg actcagtgta ttaataaatg
    16021 gagccacggg tgttggaaaa agttttttag ccacaaaaat ttttgaatac gctatccatg
    16081 agcaaattat tgaaaaagat gcaccatttg ctatcttaaa ctgtgccgat tatgcggaca
    16141 atcccgaact gctttcggca acactgtttg gatacaagaa gggggccttt acgggggctg
    16201 aaaaggatac cgatggttta ttggcaacgg ccaacaacgg ctatcttttt ctcgatgagg
    16261 tccatcgcct atcgaaagaa aatcaagaaa agctctttct atttattgat actggaaact
    16321 atcgtccagt cggtgaaaat gtaaattggc attctgctaa ggttcgtttt attttcgcca
    16381 cgacggaaaa aggtgaaaat tatttattag acacctttga tcggcgtatt caaattagtg
    16441 ttatgttgcc aacttttgaa gatcgcccca ttcgagaacg attagagctg attcaattat
    16501 tttttcaaaa tgaagcggat gttttacaaa aagatattat tgtttcaaga gaagccttgt
    16561 ctttaatgtt atctcatccc tttagtggga atattggtaa gctgaagaat atcattaaaa
    16621 tcagttgtgc ggatgtgtat agtcgaacac aagaagaacc attaacgatt gggaaaaatg
    16681 agatcttgat tcagttaaat atgctggaat ccgaagtaga aagcttgccg attgctagtt
    16741 tattgataaa gaaaaatcaa aagataaaaa cggatcgaat caaaccgttt gattatgatt
    16801 cgattttgga aaaaattact cagctgataa atgaaggtaa tttcaatgaa aatttttctt
    16861 cgataaagaa tgaagtacag catttggtgc atcacattga taaggattct tttttatcaa
    16921 tgagtagaaa attgatgatt cagatgttta gaaaggtctg ggtatccgtt ttaggaaaaa
    16981 cgtacggatt gacgacgagt ggacctgttg cagaaattat tagcagatcc tatgtcattt
    17041 ccccaagcta taagacagac ttaaccggga taaatcgtac attagctgca aatctacctc
    17101 ggacgactta cttatgtaat cagttcttgg agcatttacc accgctctca gaaaaggacg
    17161 agaactttct aagactgctt attgtcgtga ctttatctga ttatgtagat gaatccatcg
    17221 agctgaaggg cctgttgctt gctcacggag atagtacggc tagcagcatt caagcagtag
    17281 tgaatcaatt atgcggcaat tatgtttttg aagcgttgga tatgccagta gagagtaatg
    17341 tgtcagagat tgtcgaatcg acaaggaatt tcgtgaaacg gcaagtgaat acagatagtc
    17401 tagtgctgat cgtagatatg ggctctttaa atcaaattta cacacagatc aagaacgatt
    17461 taaaagggga gttacttctt ctgaataatt tgacgacttc cattgcactt gatattggct
    17521 tgaagatgac gatgaatgcg ccatttaaac agattgcgga ggatgcagca gacaagtatt
    17581 caatcaatgt tcaatacttt gaaggctttt ctcaaagtag caacattatc atttcctgta
    17641 tgtcgggttt ggggatttcg gacaaattga aagatgtttt tcgtcatcat ttatcggatg
    17701 aatccatcga agttttcacg aaggactaca gagaactacg tgaattaatc gaccaaaatg
    17761 atgaaactta ttttgacaag acaaaattgg tcatcacgac ttcggatctt ccacgttcct
    17821 tttcaattcc taatattaat gtttatgaca tcttagacgg tgatggagca gccaatttgg
    17881 agcatatttt gagtcctgaa atgaagccgg cagaatttaa ccgcttgatt caggagctag
    17941 taaaattctt ttcgttggaa ggaattgcgg accgtttgaa ctttctgaac ccaacgatcg
    18001 tgatgagtga agtggaaaca gtcatttcta aatatgaaaa ttactatcat ttcactttaa
    18061 atggccgtgt aaaactaaat ctctatatgc atacggcatt gatgatggaa cgtttattct
    18121 tggctcggac agaaaaatct gaagaaccga attatgattt gaaaccagat gaagatgaat
    18181 tttattatgt ttctagaagt atttttcaat caatggagat gaaatataat tttaaagtca
    18241 atgcttatga gctttcgctg ctctatgaat tattaggacc gtatattcaa aaataaagtg
    18301 tctaaaaaag tgtctaatct gtttttttta ggttagacac tttttttaat gtgaattaac
    18361 gtgattaaac caatgttttt aaaagttggc acaggaattg cttatataaa agtgaacaga
    18421 aagaaaggaa ttaaccatat gaagaaaatt ctaatagcga ctcacggtca cttagcttca
    18481 ggctttctta gcagtattca attactgacg gggaaggttc aagagattac ggtgattaat
    18541 gcttatgtgg atgagtgtga ttttgaacag gagttgaatg tatttgtaaa ccaggtgaac
    18601 gagcaggatc agatttttgt ttttaccgat ttatttggcg gaagtgtcaa tcagaagatt
    18661 accaaaacct ttttggagaa agagattgct gtaactattt tgtctggctt taatctgcca
    18721 attctgctcg aaatagtatt ggcaaccaag gaattaacaa aggaggatat tcaggaactg
    18781 gtaaataaat gccaacagga attaaagatg accattcttg atgaggtaca tgtagtaaat
    18841 gaagaggaag atttttttta ggaggaagaa aaatgattaa agcagtgcga attgatgaac
    18901 gattaattca tggacaagta gcgatgactt ggacaaagag tctaaattta accgggttag
    18961 tagtagcaag cgatgaggcg gctaccaacg atattcaaaa gatgacattg aagatggctg
    19021 caccatcgaa tgtcaaagtc attattaaaa cagttgatga cgcgattcat ttgttaaaag
    19081 atccgcgggc gaaggacatg cgcttgatgg ttttagtccc taatgtcaaa gatgcggtaa
    19141 aagttgcgaa agctttccca acggaaatcg aattaatgaa cgtggggaat gctgggaaaa
    19201 tgacaccgcc atcggaagat aagaaaacct tatcaaagga agtgatgtta acgacgtcag
    19261 aaattcaaga cttaaaagaa ttagttgaac tttatccaga taccgttttt cagcctacac
    19321 cggcgatgga aaaacgttca gctatctcta ttttgagtga tttttagaaa aaggaaggag
    19381 aaaaattatg tatgatgcat ttgtagtcgc tttggccgtt tttattggag ttgctggaca
    19441 tgaaatgttc gggatgtcca tgctgagtcg tccgattgtt gttgctccgt tagcaggagc
    19501 gttgatgggg gatttgcaga cggggttgat tgtcggggcg tcactagaag ccatctttat
    19561 gggtgtcgtc aatatcggaa tctctagtac ggcggagcct tctttggctg ctgggctggc
    19621 tacagcgttc gcaatcaaaa tgggaggaaa cgtggatgcg attattccca ttgtctttcc
    19681 actagcagta ttaggattac agttaatgaa tatgattttt tcttttgtat gtggaccgat
    19741 ggctgctaaa tttttcaaat ttgcaaaatc tggtgatcaa aaaggaatca tcaatctgca
    19801 cttctttatg tggtttgtcc actatgcgct ttatgctctt attccattct ttgccgtttt
    19861 atttggagca gatgttgtca aaagcgtctt ggataatatt ccagaggtca tcatgaacgg
    19921 attaacagtc gctggaaatc tgctgccggc agttgggatg gcgatgctgt tacggatgct
    19981 ttggagtaaa aatattgctg tgtggttttt ctttggggcc gttgttatgg cgtatctcga
    20041 gttaccattg attgcaattg ccgcagttgg aacgattatt gcaattgtta tagcccaaag
    20101 agatctacaa ctaaaaaata tatctgttca tgcagttcaa agcgatgctg ctgtaaatgc
    20161 aacgcttgac caagaagagg aggatttctt tcaatgaaat tagctgatgg aatttctaaa
    20221 gatgagaaaa aattggttcg gaagatgttt tggcgctcga tgactatgta tgcttcggtg
    20281 aatccggtga cgatgggcgg cggtggtttc gcctattcta tgatgccctt cattaatcat
    20341 ttctacaaaa gtgaagaaga tcgagctgcg gcgctggaac gtcatacaca gtatttttcg
    20401 acgaccattc cttgcgcgtc ctttgtcatg gggattgcgg catcgatgga gaaggaaaat
    20461 tctgaaaaag ctggttttga cgtggaaagt atcaacgcga tcaaaacgag tttgatggga
    20521 ccattggctg gaattggcga ttcattgttc tggggagttt ggcgtgtcgt taccgcggga
    20581 ctagcgatca acttagccaa tgccggaaat attttggcac caattatctt tttagttatg
    20641 ttcaatatac ctaattactt gatgcgatac tatggcggcg ttttaggcta ttcattaggc
    20701 tctaaatata ttgaaaagct gtatgcgaac gggttaattg aaattctgac aaaagctgct
    20761 agtatcttgg gtctgatcat ggtaggtgca atgacgatca gtatggtcaa attcaatacc
    20821 gttttgagct tttcaatgaa gggcgaagaa ctaatgaatg tccaagaaat cctcgatagt
    20881 atttttaaag gaattgtacc gttattggta acattgagct gtttcaaatt actagataaa
    20941 aaagtcggcg tcatcaaaat tatttttgga atggtcgtct tgggaatttt attgtcatta
    21001 cttggaatcg catagtagga agctgcagct actaggctgc agttttttta gcaaggaggg
    21061 aaaagatgac tattaatgaa gtaatttatt cacccaaaca cccatttttt aatgctgagt
    21121 taaacgacgg aaatgtgact acttcaaacg aatacagcta ctatcggaat attcctgatg
    21181 taaagggatt gaccttcgat gtaagtaatc aaaagacatt agcaaacctt gatgtttgcg
    21241 ggacgattca aacgttgacc ttttatcgag aaaatttact aactgaggaa aaaccaggtg
    21301 tttgggtcaa taaacagctc tctcaaacca attcgttatc cttaaaggtt gaagtaaacg
    21361 ggattgttta ccatttgtca gaatcggatc atcgtattga agtcgatgtg attcaagact
    21421 gtttgcctag atatattcat cattattcga cgtttaaggt cattgtagta tcctttgctc
    21481 ccatactggc taataagcgt ttaagtatgc ttgttcaaca ggtttacatt gtgaatgaaa
    21541 cacacgaaag ccttcaagtt tcagtgaaag atgtgccttc gtatcaagag aagtattcgg
    21601 atcagcaaaa tgtgttgatt tctcaaaaag gaaataagga cacgatcgca caacaggaag
    21661 tggcaagctt cgccattgct tttgtggacc caaatgcttt tgaagaagta atgacttttc
    21721 aggaatctga tatcgaaaaa tggctgaagg aaacattgaa ctattttgct cagctatttg
    21781 ggcagctgtc aatgccaaac gatagagttg tccatctcta tcgtcgtgca ctttatcaaa
    21841 gcttttctag tttcggtatg aatcgacagg gacaggtcgt cggcagcaat tggggcagct
    21901 atcctgctac taatcgaatt tggaataagg atatgtatta cgcatcattg ccattcacca
    21961 tgtttgaacc ggagttatgt caaaaaacgg ttctatggtt tgatcaatat ggcgttaagt
    22021 ttcctggttc aaaatttaca ggaggtatca atcattctct gagtaattcg ttatccagtg
    22081 cgttactggc tagtctttat tttgaacata ctggggatac aaaattcttt gagcggtgtc
    22141 cgcaggttct actgaatgct tcaagaatta ttgaggacat attagctcaa cgtcggtcag
    22201 gggaaccaat gctttttcca tctgtttggt tatcagacgc ctttgcactt ggaaagtatc
    22261 ataccggcag caatctttgt ctttggaagg cctgtattgg acttgcagaa atttttgaag
    22321 ccctagaaca actgagtctt agcaagcgat acaaaaacat tgcctgtaaa ctaaaggaat
    22381 caatttgtaa acaaatgact atcgatggtc cttttggtga gcaatttttg gagggaatcg
    22441 gtgatgagga gaaaacaacc tattcagtga agcactatca aaaaccgatt cttgagcaag
    22501 ggttaatctt tttaagtgat gtgattgtgg atggaaaaat taatttattg atgcatgatg
    22561 gagaagaatc agacactacg ttgatgcctt tttatcaatt tttagataat aaagatcatt
    22621 tatatcagaa caccatggcc ttttctgcta gttctttcaa tccaacctat agcgaggaaa
    22681 tcaaaggcat cacttgggga ttagaatccg gcgccacttt tcctggcttt atcactgttt
    22741 taatgagcga gctgcacaac cctcaagctt tcgtaacccg attagaagaa ctaatttgtt
    22801 tggcagattt agacggttcg tggtggtggt ggccgtatcg cttagaggct caacaaggag
    22861 aagtcgtgcg agactttggc tgcggcaaat gcggctgggc atcgggtctt tttgtcagcc
    22921 taatgatcag tcaatatttc ggattgaaat tcaaaaaagg agtattgcaa attgatcctg
    22981 ttgataattt aacgttttct tggaagaatt tgaagttcgg tcaagccttc atttcgattg
    23041 aatgtacgca atccgagttg agtatttcaa atttgtcaga aaagccattg aaaataagtg
    23101 atacgaaaaa aattcttcac gtagaaaagg gaaaaacgat tcacattcaa aggagaaaaa
    23161 gatgagtata ctaaaaaata ttacccaatt taaaaaaatc cagagtcgag caatcactcc
    23221 cgaaaatcca acaggcgaga aaggtaaagc tgcgatgttg ccaagcgagc taggaccaag
    23281 ccgcaaaggt cgtggcgcaa ttccgctgac ttctggtgaa gaaactgtga ttgcggatat
    23341 tactggaacg ggaataattc gtcatatgtg gatgacgatt cgtgatcgaa cagaatttgg
    23401 cagttttgtt ttacgtgatt taatcttaag aatttattgg gatgggtcgg atagccctgc
    23461 tgttgaaagt cctttagggg atttcttttg taatgggttt ggagagcgtt gcgaggtgaa
    23521 ctcgttgccg atagtggtta atcctacagg gggctttaat tcctatttcg aaatgccttt
    23581 ccaaacatcc gctaaaatta cgatcgagaa tttacatccg aaggatatgt cctcattttt
    23641 ttatacgata aattacgctt tggtggacga attggaagaa aatagcctat attttcacgc
    23701 aaattggcat cgggaacgca ttaccaaatt acaggaggat tataagttaa ttgatcgatt
    23761 aaagggtcaa ggctattacg tgggtactta ccttgcgctt acctgcctag aacgttattg
    23821 gtggggcgaa ggcgagttta aattctacat tgatggggat agtgagtatc cgaccgtaac
    23881 ctcaacaggt tcagaagatt attttggcgg ggcgtgggcc tttcatgagt acgatgagtt
    23941 cggacgtcca catgcgaaaa actattcaac agccttttta gggtatcctt accaatcaaa
    24001 tagagatgcc acaagagatc gttttgaaac gggaaaattg aatgccgttc atgcctttgg
    24061 tgacgacgca atgccacgac atggtcttta tcgttggcat cttcaagacc ccatctgttt
    24121 taccgaagat ttatcggtca ctttacaaca aatcggcaac gatgatgttc gcttatttga
    24181 gcggcaagac gatgttgcta gtgtcgctta ctggtattca acagaagctt caggaaatac
    24241 taaacgtcat ttcactgatc gagaacgctt gccgcgttaa tgaagtgttt ttcacatatt
    24301 cgaagggagg aacctatgat gatatatggg gcaattgaag ctggagggac taaatttgtc
    24361 tgtgcagtcg gtactgagga attaacgatt ttggaaagag tcagttttcc cacaacaact
    24421 ccagttgaaa caatgaagca ggtcattgat ttttttaaac cttttaagga acaattggca
    24481 ggcatcgggg tcggctgctt tggtccaatt gatattcaat gcaaatcaac gagtttcggt
    24541 catatcacat caacaccaaa acttgcttgg caaaatttca attttgtagg aacgctaaag
    24601 caatatttca atattccgat tgaatggaca acagatgtca atgcggcttg ctatggtgaa
    24661 tatgttgctg gttctggcaa agggttagca ggtgttgcat acttcactgt gggaacaggt
    24721 atcggaggtg gtgccttgtt caatgggact ttcgtggaag ggttcagtca tccggaaatg
    24781 gggcatatgt tgatcaagcg acatccaaag gacaattttt caggaaactg tcccttccac
    24841 caagattgtt tagaggggat ggcagcagga ccagcgattg aaaaacggtt gggtgtaaaa
    24901 ggccagaatt tattggctga cgattcgttt tggcagattg aagcctttta ccttgcccaa
    24961 tgtgcataca atacaacact gatgttttcg ccagatagaa ttatttttgg cggtggtgta
    25021 atgaaacaag aacacatgaa gaaaaaagtt caggataaat ttgttgagct tataaatgga
    25081 tatgttgaaa taccaccaat tgatagctac attattacgc ccgaattagg tgataatgcc
    25141 ggaataatcg gcggattagc attggccaga aaagcggtaa gaaataagca accataatta
    25201 atgaatgttt cattgatact catgtcaaaa gtatttaacc gagtaatcaa atgatcaaat
    25261 gaagttggat aaagcgaaaa tgaattcaaa taaaaaggct ctaagtcaaa tcgtgttgtt
    25321 ttcattaaat cactgaaagg aaatgcttct gcgtttcctt ttttcttttt gttgtgcgct
    25381 gtataccttg aggatattca ctggtggcgt acacttaaat agtaatatat tgtgttactt
    25441 tatgtctgtg gtaatagtta tagttgctta ccaatgtatg ttcatttttc gaaatgttga
    25501 cttcataatc cttggcttaa tgtttgaatt tttttggtga tagatttttt cagccgtata
    25561 aaataaatcg taattctatt ataga
//
LOCUS       DADVXM010000034        24747 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.035, whole genome shotgun sequence.
ACCESSION   DADVXM010000034 DADVXM010000000
VERSION     DADVXM010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.035"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(57..173)
                     /locus_tag="KB927_001465"
     CDS             complement(57..173)
                     /locus_tag="KB927_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HBB6840390.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            complement(418..1332)
                     /locus_tag="KB927_001466"
     CDS             complement(418..1332)
                     /locus_tag="KB927_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6840391.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            complement(1347..2348)
                     /locus_tag="KB927_001467"
     CDS             complement(1347..2348)
                     /locus_tag="KB927_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBB6840392.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            complement(2345..4528)
                     /locus_tag="KB927_001468"
     CDS             complement(2345..4528)
                     /locus_tag="KB927_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBB6840393.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            complement(4531..6978)
                     /locus_tag="KB927_001469"
     CDS             complement(4531..6978)
                     /locus_tag="KB927_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6840394.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSDGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            complement(6962..7354)
                     /locus_tag="KB927_001470"
     CDS             complement(6962..7354)
                     /locus_tag="KB927_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6840395.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            complement(7441..7938)
                     /locus_tag="KB927_001471"
     CDS             complement(7441..7938)
                     /locus_tag="KB927_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBB6840396.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            complement(8055..8279)
                     /locus_tag="KB927_001472"
     CDS             complement(8055..8279)
                     /locus_tag="KB927_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840397.1"
                     /translation="MSGTYLSIYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFL
                     IIAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            complement(8383..10293)
                     /gene="ltrA"
                     /locus_tag="KB927_001473"
     CDS             complement(8383..10293)
                     /gene="ltrA"
                     /locus_tag="KB927_001473"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBB6840398.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(11077..12282)
                     /locus_tag="KB927_001474"
     CDS             complement(11077..12282)
                     /locus_tag="KB927_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBB6840399.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(12305..12458)
                     /locus_tag="KB927_001475"
                     /pseudo
     CDS             complement(12305..12458)
                     /locus_tag="KB927_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(12461..13846)
                     /locus_tag="KB927_001476"
     CDS             complement(12461..13846)
                     /locus_tag="KB927_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBB6840400.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(13875..14261)
                     /locus_tag="KB927_001477"
     CDS             complement(13875..14261)
                     /locus_tag="KB927_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6840401.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(14277..14591)
                     /locus_tag="KB927_001478"
     CDS             complement(14277..14591)
                     /locus_tag="KB927_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6840402.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(14944..15423)
                     /gene="rlmH"
                     /locus_tag="KB927_001479"
     CDS             complement(14944..15423)
                     /gene="rlmH"
                     /locus_tag="KB927_001479"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBB6840403.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            15851..17140
                     /locus_tag="KB927_001480"
     CDS             15851..17140
                     /locus_tag="KB927_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBB6840404.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(17179..17784)
                     /locus_tag="KB927_001481"
     CDS             complement(17179..17784)
                     /locus_tag="KB927_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBB6840405.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(17980..18444)
                     /locus_tag="KB927_001482"
     CDS             complement(17980..18444)
                     /locus_tag="KB927_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6840406.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(18466..18786)
                     /locus_tag="KB927_001483"
     CDS             complement(18466..18786)
                     /locus_tag="KB927_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBB6840407.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            complement(18929..20008)
                     /gene="pepA"
                     /locus_tag="KB927_001484"
     CDS             complement(18929..20008)
                     /gene="pepA"
                     /locus_tag="KB927_001484"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBB6840408.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            20208..20558
                     /locus_tag="KB927_001485"
     CDS             20208..20558
                     /locus_tag="KB927_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBB6840409.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            20743..21696
                     /locus_tag="KB927_001486"
     CDS             20743..21696
                     /locus_tag="KB927_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6840410.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            21709..23496
                     /locus_tag="KB927_001487"
     CDS             21709..23496
                     /locus_tag="KB927_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840411.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            23483..24685
                     /locus_tag="KB927_001488"
     CDS             23483..24685
                     /locus_tag="KB927_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840412.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
BASE COUNT         6992 a         5007 c         4518 g         8230 t
ORIGIN      
        1 gcatcaacat gagctaaaac tccaatatta ataattttca tgtgattttc ctccattcaa
       61 aagcccaaaa gggcataaaa atcccagtga taaatactct tatcactggg atttttatgc
      121 ataaccatag gcatacaaag catacagata ttctccggat actttagaat cacatgataa
      181 aggtattctt aaactgggtg caaaaaacta agccctccta aaaaaggaca tccaattatt
      241 tgttcccact atcaaattga cagtttattt aagaatacct tgccgcatat ttattaactc
      301 cttttaaata gatacttaaa taatagcacg taagagcata tttgtaaagg aatctccaat
      361 tttttatcaa agagagtacg tgattacaaa atagctgtaa taatgtacca atatttgtta
      421 ttctataatc ttccaattac tcccgttctt ttcaagtacc aaatcaaatt gagatacctg
      481 cgttgctttg gtctgctggt cgatatactc cactgtcagc gataccgtga cttgattatc
      541 cttacgattg taaataggat ttaccagttc ttgaaagatg tactcttttc cgattggttt
      601 taatatcccg tcattcacat agtaggaaag ttcactggct gtcgctgtag gatagagctt
      661 gaagaacgtc gttaaaaact cattgatttc attggttgta atggaatcaa ccgtaccctc
      721 actttcaata gcttttggtt tatagtctga tttctttggt atgctagtaa tggtcggatt
      781 cttaatgagg accatatttc cagtactgtc tacatagaca ctcactatat aagcagagtg
      841 gacggtcttt gtattttccc cctctgtaat gagttggtct acactgtagg ttacatcaaa
      901 ttgattgtcg ccatctgctt ctaccgtcca tatctgaaat ccttttacag aagacgatac
      961 aggaatatct ttacgaactg tatcgacatt cagagcttga agttcctctg tcagatatgc
     1021 tttcaggttt tctatgcgat tatcaatgga cttgtcgttt agttcccatg aatagtagac
     1081 tttcgcaaag ttctctacaa aattttccac atgatgagta tcgacatatt ccttttctat
     1141 gatggtggtt tcatgaatgg tatgggtatc aatggctgta aagtgcttga atatcgcaaa
     1201 gctgaaacta agtcctaaaa gtacccatag gacaatcaca acctttttac gaggattgac
     1261 cttatagaca cgaggtttct tttcctttgg tgtctgtttt tctgtattct gattttttcc
     1321 gaatttcatc attgaatcgt cctttcttat tgtttgattc gtcctgctcc cactaaatgc
     1381 tgttgccagt aagagcttgt taagtcggca taaccgatag ggtcgcctgc atgaaacata
     1441 cggttatcgc ctaaataaat cccgatatga gtaatataag agccagcgtt ataggtagaa
     1501 tgaaagaaaa ccaaatcgcc ggcttttgct tccaataatg ggatatgccg ggttacatca
     1561 tattgctgtt gtgctgttcg tggtaagttg attccagctt ttccatacgt ccattgtgtc
     1621 agtccgctac aatcaaaaga ggtagtcggg gaagctccgc catagacata cttccagcct
     1681 tcaaatttca gagcttcgtc catgatggct tgtactgtat catcatcaaa ctctgttgtg
     1741 acaagatact gcgttaccag ttgcacataa aacatattcc cgtaattgta tcgccagccc
     1801 ccattgatag gtatggctat gggattgggg taagacactt tttcgtcacc cgaatactct
     1861 tttgagaaac tttgagccag ttcaaaggta tatttattcc cacgattagc cacatatcct
     1921 aagaaaccac caccataatt gtaggactgg ataaccgatt ctaaatctac accaagcctt
     1981 tcgctactgg ctaataactc actgaaatac ttcacacctt gcttaatgga ttcttctgta
     2041 ctcaatgaat taggtggaag accgagggat tccgaggact gcataacatc ttctgctgta
     2101 ccacccgatt ccacctgtat aatcgcaaga agtatattga cgtattcttc aattccatat
     2161 tctttggcaa ctttttctac cataggctta tgagccagca cttctgcgga aacatccaca
     2221 ccgccatagt gaatgttgga aaaaccgcca tcttgttcat ctgaaaataa aatggcgaca
     2281 aacagaagca gtgagaagac catcaagaat aatcccgaac caccaatcac taaagttttc
     2341 agcttcatgg tttcttactg cctttcttaa tggtggcggt tttgattggt ggtctacttt
     2401 ttgtattttg tagtggtact ctttgaacag tagactgacg ttcttttgtg attgaacgtt
     2461 gtgaagctct atctgttggt gcagttgaag ttactggctt ttgaaccgtt ctttcttgaa
     2521 ctgtattact ttgacgttcc gtttttaaac ttgaagaatc ggacttaact gttggacgct
     2581 cttgtttggc ttgttgagat tccctatagg aagcctgtac agttgtttgc cttgaagtct
     2641 gtccatcatg agattgttct tgcttagtgg ctggtctttc atgaacggaa gaagctggct
     2701 gttttttctg tttgacctgt tccatttcag agcgacgctc cgcaatggtt ttccgtcttt
     2761 gttcctgctg tttcttgcgt ccactggctt tatccgcttt ggtttgagaa atacttctgg
     2821 ttaaatcatg gacattatcc gtcactttag attttccttg atatactgca tatcttgcat
     2881 tggtcggcaa atccttaacc tgttctttca aattaccagc agtatctacc attctgtctt
     2941 tggtatcagc tactgtaccg atggtttgac cgatacgctt tcctagtgtt gatttttcct
     3001 gcccgtttgg tcgagagtga tctgcttgtg tactcgcaga acttcccgaa cccgactgtc
     3061 cttttttacc cgtagcactg gcaatggcag acccagcccc taaagcagtc acggagcgtc
     3121 caagtttccg ctgtagacgg tgcatgtgag cgtgcataag catacgaggt tttctcatca
     3181 tacgacttcc cacactttga gaatcgttac tctgtagaga aaacatactc attaaatcgc
     3241 ccagcttaaa gtagattcct gcaaaggtca caatctgtag aaaagcaatc aaaaagaacg
     3301 gataaccagc cgataaggta tagagcatgg ttgaaatact aaatgctgtc gtaataatca
     3361 atgtgattcc agctcgtgtc aaaatggtat taaagagctt tgttatggct cgttttgaca
     3421 taccatcaaa tgatggaatc atgcttaaaa taaagctcac aggcagaaac atagcataga
     3481 tgataaaaag tacctgcgag aaaatcatga ttcctgttaa taggaataca aatatggaaa
     3541 tcccaatatt gaagacaaat aggaagaaga ctgtacctaa acggttaatc gtctttgtaa
     3601 tcgtcatatt ggtattgctt ctatcttcaa tttcttccgc aacaattttt tctctgtctt
     3661 ccccattgtt ggaatctgga ctggttgaga gcaggctttc cacacggtca ataccaatac
     3721 tttcaatgtc tgaactgtta tattgaagca gtagccacgg ttgctgaacc tgtatggaaa
     3781 ataggctgtc acgtatcaag tccacactgt ccttgccttg actatctgaa tggggcatga
     3841 caatttttgt acccagtgac aaactagcgt tgctgatgtc tgatgaaaag tcattgattt
     3901 ttttaatgta gtcgggagcg taggcaataa aggaagccga taggataaaa accagcacaa
     3961 aattcatgag ggcatgaatt gcctttgtgg tttctctctt tatcagtcct gtataggcaa
     4021 cataaacccc aagaaccaaa atcaagagta aaaggaatcc aacatagaaa ccctctgttg
     4081 atagtccact aggcgtaacc cctgcaaggg tctgcatatt cttgccaatg gaatctgctg
     4141 tagcggaaat gaagtctaag gaataggctt cctgtactaa gtaacccgtc gcattggaaa
     4201 cataaagact gattgtccaa ataaaattgg taatggcata tagtccatac atgacttgtt
     4261 ttccaattcc gtccgaccag ttccacggta gccagcccca gctattatcc acataaaaat
     4321 ccagttgata gttttcaagt gggtatcggc tgtattcatt tgccacattg accgtatcat
     4381 ctaccaagcc cgcagcttga accaccgttc ccagcatggc taaaagaaaa atggcaatca
     4441 caagtgtgaa agccactgtc attgccactt tacctagacg tttcagcgtc cagtttgatt
     4501 ttattctgtt taatattgat ggtttcacat ttacacctct tttcgcacag gtggtctggt
     4561 atcaaaggca tggagcagtt cttcaaatac agggtggaac tgtatcacac cgacacgacc
     4621 atataaatca ctgataaggc attgcccgtt ttccaaatca cgcaatcgct tctgattgtt
     4681 ttcgtcctct gggtctacac caaaaaaggc aagggttttt ttaatctcgt taaggtcagt
     4741 ggaacgaaag gcaaatttta agccgaggtt atttttcagt ttttcatcta agaggtcatc
     4801 tgtattttgg gtcacgaaat ataccccagc gttcatagca cgaccagcac gaaccagctt
     4861 catagatagt gttttccctt gtgccacctg taagaagctc catgcttcgt ctaagtctac
     4921 aatcttgaaa atacttcggt ctgtatggat aaagtccaac gcaaaggtac taatgacaat
     4981 cagcattgct accgatagta actccattgt ggtatattcc tcaaaggaag tttccttgtc
     5041 aggaagtacc aagtcggcaa cctgtataat gttcagttgt ttttcaaggc tgatagactg
     5101 ctctacataa ccatcactaa aaagcagatg ggcaaagtca tagtctgtaa aactttcgat
     5161 atggtcggct atgctggtac ttagtggcgt attctcaacc cgtaattctt caatcacttt
     5221 catcaaccct cgcacttcac tattggttac tgcacgaatg gcttttctaa ggattgggaa
     5281 gcgttcccca tcacgagagg aaatccccgt aaggaatgtc aaaatatcaa tagccagtga
     5341 ttcagaatct ttggtatttt tcataattac ataagggtca agtaagcctt tgtttttctc
     5401 atcagaagtc agattgacga tattgatttc atgggaaatc tctggcaagg tttctttcca
     5461 tctgccacgt tctgcttttg ggtctacaat cactgcttgt gccccataaa gcactgcata
     5521 atagacgata aggttattcg caaaggattt accaccaccc agcgaaccga caaaggcaga
     5581 cgctaacgca ttggttactg aacccttaac cccttgactg gcaagagcag gtttcagata
     5641 gacattgcgt ccagtatcta agctgtagcc aacataaatc ccctcatttt cacccagcat
     5701 ttgagtagca ccaaaaccta aaccagcgag gaaatcagag gtcacgtatt gaatatagtc
     5761 attcatatat cttttgctgg caggtaaaaa ttcttcatgt aagcccagca tatccccaaa
     5821 aggtcgtacc agtttcacgc tcaaatcatc atagaaatct ttcacttcat tacaacgacg
     5881 tttaagttcg tcaaggtcat ttgctgatac ccttacaaca taggacagct tatacataga
     5941 ttccttgctt tggtctaaat tggtttccag ctcgttcaca ctttccagag cttccgccac
     6001 attagagctg gtttcattat cactttgcca agcgtggtta tccaagtctt tcagttcttt
     6061 ctttttattg cggacagtag atagggcttt acgattcgct acaatttcca cattcattga
     6121 cgtatcaatc ggaaaggtaa attgctgttg ctggtagtag aagatttcag aggacgggaa
     6181 gtccagttcg ccgacaatac tgttgatggt aaagtaagct acataggcgg tttcgtcttc
     6241 ctgctggatt ttcaaatatc gctgtttttc ttccaccaga cagcgagtag gcttaatgag
     6301 gtcataggtt ttaatcagtg tttcatgttc cagctttttc tttgatagag gatactcata
     6361 ctcttcatag gcagtgcctg tctgtccgta aaggtgttca atcagatagc cgaagtcatc
     6421 cttatctaat cttcggattt tgaaacgacg ggagatttta ttttctaaaa gcttttccat
     6481 cttctgaaaa cgcaggattt catcattact catactaaca aaatcgccca tcagcttatg
     6541 gttcacatca tagacaaaat cagtaaaagc attttttgct tcaacggtaa gacttttcat
     6601 agaaaactcc tgatcgttga gaagcaactt aaaaccgata aagaaacggt agtccacttg
     6661 attttcgcca atcatggata ttaaagcgtc tgtctgttgg tcgattttgt cataggcaac
     6721 cgttttgagc tttccagtga cttcattttt ggaacgttct tgtgcagaaa gtatgctgga
     6781 ttctgtactg atttgtaaag catgaatctt gccatcacga ttttgtgcga taagctgtct
     6841 gaaagaatca tgtacttgta ttttctgttc cggacttaga aatgagtaat tgtagggaac
     6901 aagctcatag taagcgtaac attccccatc tttattccag accagattgt tttcaatata
     6961 tttaattgga tatgccataa aattcactcc taactgctgt aatggcttct tgtggctggt
     7021 ttctgccaag cgttactttt tttcctgcat aggtcagctt tcgtcgcagt gcataagcaa
     7081 tgacagactt caaaaatcca taaggctttt taccatcaaa ggtttttgta gacataaacc
     7141 atgtgaaagc cacaggaatc ccaaagtatt tgagaaatgc tccctctatc atagaaagag
     7201 ggggcaagtt gccaagtatc ataactgcaa agagtgacac gacaaaccat gtcatttgcg
     7261 taaaggttat gggaaacgga agtctaaagt cattgatgga gtacaacact ttctcaacag
     7321 accagatact ggtatagctt cgtattttct tcatgtaatc aatcctttca taaaaatggg
     7381 gatagtcttt tgactacccc gtaaacaaga aaatctgcca gtaagaatgt accgacagat
     7441 ttaatagacg atttcaaaaa tcccgtgatt ggttgagata aacgttcccg aaaggtctaa
     7501 atcccgacca taggattcat aatcaatata gttttgaaga ctggctggca cttcgcctaa
     7561 agcacccgtt tcttcaatgt agtagcgtgc cacgtcagac atatcatcac aatcggaatg
     7621 aatgataata tcttcttgat gttcgcttag ttcttcaata cttgaaaaat gagtgagcag
     7681 agcagatagc tccgattgta gttcttctgg caactccgat accatttccc ataggcgatt
     7741 gagttcgcta atagaagtgt attcgtcaac cgtaaagggt aactcgtaat catgaatggc
     7801 gtattcctca tattcatcat tcaagccgat tttctctttg acttcctcaa agtcaatggg
     7861 aaaggtaaac cacgcaccga ccaattcgcc ctcattgtat ttgcctaaat tcgcaatata
     7921 gacttgcata tcgtccatat attcacgtcc tttctttgta gagattcaaa aatccctacc
     7981 gcacttcgtt tggtgtacca ttcctttgcg gaacataaga aaaccactta tattccacaa
     8041 aagaacggtt ttatttaagc accaataatg cgattgaata gctctagtaa aatgtctttt
     8101 actccagcag cgttgaagac taagccaacc gcaataatcg caataattaa aaagccaatc
     8161 agtttgctaa actcacgctt gaagccaaga tacaagccaa tcacaacgat tgctaaaagc
     8221 accagtgatt gagcgtttga tagaaaccag ttatatatgg ataggtaagt tcctgatatt
     8281 ataaatatct caaacttttc cccccattca cacggagcgt gcgactttca ccgcactccg
     8341 cgttccatcg tgtttatatt gaaaagtatt tatgtagtag acctatatca agtttaattc
     8401 ttgattgcca gctaatactc tatatttatt tagtcttatg agctggactt tatttagctt
     8461 caatagagct atatattttt gtattgtttc ttctgtttta gcgtgtatta gacggtgtac
     8521 cgcctctttt accaaaataa gatttttata atcgtcattt ccaccagctc cagttggtac
     8581 aatatgatga caatgtattt cattagcttg ttgaaattct tccagagtta tagcacattt
     8641 tccatgttga gcagaaaata gcgaaattcg attgtctgcg tattctattg tgcgattttc
     8701 caaagataat ttcattaact ggtacatcag taatttatca acacttagat tggtgtggat
     8761 aaattttctt ccctctagag tgtagcaatt cgctaaatac acctttgcca ttggttttct
     8821 gtgttggata tatccaacag ggaaaatagg ttcgccctcg ccagcaacat accgaagcat
     8881 tttagattta ccatatcttg ttgcctcctt tgtcgtaagt tgtctgcctg tttttctcaa
     8941 tctgcccctt ttgtttgtac ctaatctgtt agtgaagata gccattacag ctctattcag
     9001 tttcatacaa tccagattta cattcgttgc aatctgataa taattttgca tacctaatac
     9061 cattgaatta taaagtcttg tttcttctaa ttccgttttc ccttttgagg gagaagcaat
     9121 tttctttgcc tgtgatacca gcttgtcttt ttggtttttg aattgtttat cacttatatg
     9181 tgatttaaca actaacttct ttcttctcgg tatcatttta atcttgaaac caagaaagtc
     9241 ggagtatctt tttctaacat ttacaattct tgttttttct tgtgatactt ccaattttaa
     9301 tcgttgttca atccattgag tgattgctat tttggctttt tcagcacttt ccttgtagcg
     9361 gcagaaaact ctaaaatcat ctgcataacg aaccatatac atttccttta actttgtttt
     9421 cttcatttct ttgtaagcgt tgcttttaca tgggctaccg cttttattga tatgaaccac
     9481 atagtttttt gtaacaggat tttcctgcca ttggctttct acccaatggt ctaactcatt
     9541 aagaacaatg tttgctagta gtggggatat tattccccct tgcggagttc ctttctctgg
     9601 atatgttatt gtaccgttag tcattttgat tggagctttt aatatccttt ttaaaatgaa
     9661 tatcaagtgc ttgtcccgta ttcccatagc ccatatctgt tttatcagct tggaatggtt
     9721 cacgttgtca aagaaaccct taatatcaaa ttcaatcaca taatgtagct ggctgatttg
     9781 taggcggtta taggttgctt ttattgcatt ttcaactgac ctattaggtc taaaaccata
     9841 gctgttttca ctaaatttag cttcgcagat tggttctaat acttgtttta tacattgttg
     9901 tataagcctg tcccacatac aaggaatacc tagaggtctg gttttaccat ttggttttgg
     9961 tatttctttt cgcctcactg gcttaggtcg atacccatgt ggactgcctg caacaatgta
    10021 tcttactttt ttgacaactg tttctgctgg caatttgcca atatctttaa ttattgtacc
    10081 gtctgttcct gctgttttac tgcctgcatt tgctttgata tttcgatatg ccagtaatat
    10141 attttctctc gataggataa tatccataag atgagtgaaa atatctccat tcttactttt
    10201 ggcatataaa tcatcaaagg tgttttgcat ttcgtaatat tcagcgtgtc ttaaatcttc
    10261 tacacacaat gtttcatttt tatttttagg cataaggctt cactccttta cttgaaattg
    10321 agtgagcttt tttatcttac tcgtaatcct tattgaaaca acataatact tttctaatat
    10381 atacacgact tgagggcatt cctccattct cattacaaga atttcttagg ttcgccctct
    10441 gcttttcagc attagttcaa ctgcttattg ttcttcgtca gtttattctc ttgatgagaa
    10501 cccaatacct ttcctcgttc cgataatctt atctatacat atatatcctt aggtcactag
    10561 ctataagcct gctggcttga taccgcctgt aacgttatat ggcatttcat aacctatatt
    10621 cttactttgc cacaccagct acgatttctc gtacctttgc atttctacaa agttcaaatt
    10681 tagacccgta cattcgctgt ttcgtcagtt ccttatagaa cattctaacc atagatattt
    10741 tatagacccc cgacctgttg gatacgctac ccacctctgg atagttttcg atagaagata
    10801 tatgttcatc aactattacg gtatctttca gccgtcttta ccgagcttca aacattctga
    10861 gtttcctcat acaatgcttg tcggaggctc agggcaggcg tttcagagcg ttacttcatc
    10921 attccacctg tcagattatc agttctccta ataaccaaac tttttcgttc ttttattagt
    10981 gccttagctt ttcactaagg aacgagtcgc acaaaggttt tgtccaaaat tcataaaaat
    11041 gttctcctct ctatattcaa tgaatttgta tttgagttat ttttttgttg ttatcacgtc
    11101 ctgttctttt actgactgtt gcttcaaaat ctgcttgtgt cggtctgtca gtttcgcatg
    11161 gtcgagaatg tcttttacaa cctgcgtctg gttgatttca tcaagtttaa tcgcaacctt
    11221 taaggtcggg gcaacttgat gagatagcca gttcagcgtc ctttggaagg agtaaggctc
    11281 tggttttgtg gttagtttta atcgttcacg attgttccca ataaaccaag cccattcttc
    11341 attcagtttc caatcagaac gaggtttgga atcgtcttta tctacaaaac ggatataccg
    11401 attgataatt ttaaaggcgg tatgctctgg attgtcatag acgagtaaat cacggactgc
    11461 ataataggca cgctcatttt tcaatcgaat ctcaaaacgg ttttttactt ctgcgtcttc
    11521 aatgggaata tcatttttct tgtactgctc gtagtccttt tcatagatac agaaataaac
    11581 ttcactttgt aatgaaccga tatagagggt gtttcccata cattcctttt cctctttgcg
    11641 taccagttcg ccactgcgat agcttttaaa actgcggaag acggagatac attcttcctg
    11701 ttggcacttt tcagtgagta cagggatatt taaaatccct gtcttatcgt taatggcaag
    11761 gtcaaggcgt ttcatcacac cgccagccac caaaacgtcc ataaagaact cataccagct
    11821 tctttgttgt gccagaagat agctttcaaa ttgtctgcac ccacgacctt tcaattccac
    11881 cagaactcct ttgtccagtt catgggagca aaggacgaat atgtcgccta aagcataatg
    11941 ctctgaataa gaatagaaac catagtcctc atgaagaaaa taggacagtt tcagttgtaa
    12001 gatgttttcg accacctgct gtacgtctgt tgtcggaaag cgaattctta cataatcaaa
    12061 cagcatttca aggggagcgt cgggattgaa gcgttccaga gcttcccaaa gggactgctg
    12121 taaatcctct gatggcttga cttttcctgt ttcaatatcg cttagatact gccttgtaat
    12181 accagtcgca acagctaaac ggttttgaga tagtccataa gccaagcgtt tttcttttaa
    12241 atgctgtaac caagtttgtt cattcagtaa aaatccctcc aatcaaaaag gcgtatgtca
    12301 acttttaaag cccatttgac atacgctgaa attttgtaaa tcccttgtaa ccaaaggatt
    12361 ttctaatgtt tttttgactg tttcctgtcg atttgtaccc ccctgttaga taccgagggg
    12421 ttaagtgctg gcgtggctat tgccacacca gccagcaaga tcagtccaca cctgcgactt
    12481 ccgcttcgca cgtcgcctgc gtggactgtc tgctgttgga taacttttta atttcctcca
    12541 agaaatcata tccttttggt acaaggggag tataaaactc tgatatgaca cttgttccta
    12601 catcaacata gccacgacct ttgattcgct ttaagaagaa atccttttgt acgtcactgc
    12661 caaacatcat gccatagccc atttcagaca tacgacctaa agccactctg aaattaaact
    12721 gatcacggat tccgtcgcct aaatattttg cgtctggacg ttgacaagcc agtattagaa
    12781 agaagccagc ttgacgacct aacatgacaa tctgtttcag cttattcata actgcggtgt
    12841 tttcttttgt tcccagcatt tccatgaaag cgacgtattc atcaaagatt aagaagtgtg
    12901 ccgggagacc taagtaagca taatttttgc cagtcttata gttcttcatc tgcttcattt
    12961 cctcactacg tttcatcatt tcttcataga atgtttcaat gcaagaaagc aagtcttctt
    13021 ttctatagta gacatttgcc atcacagaac ctaagtccgc aaggtcagca tttttcgggt
    13081 caagaatata cagttttgaa tctgtatgaa gcaaggcttc aatcagtgtc agtataaagt
    13141 aagttttacc gccacctgta ccaccagcaa tcaacatatg agggagctta tcatattccc
    13201 accatacgtt tttcattaag cgaagtttac catctttagc ttctacttca tcaatagaaa
    13261 tacgactggc tatggtgtca tagagcaaag tatattccac ataggaatcc tttaactctt
    13321 tatccgtcag ctcacagtac aagccactct ctaatttctt ttccaagtgt aagagttggt
    13381 cttgatattt tcccagcgtg atttccaccc gtatctgtat caagccattt ttaagtcgat
    13441 aatacatttt agggaagtag gttatctttt cctttgtacg accagcacta tctttaaaga
    13501 aaccctctgt tttgacctgt tcagattcat accacttgtt ttcaagtatc atctttgcca
    13561 gtttttgacg gtggtaaagt tgtttaaccg tatcatagcg aacccgtttg aatacaaacg
    13621 ctaccagcaa gcagataaga attgcgacac tgaaactgat aattaaatag ggaatgtcaa
    13681 tcttatctgc ttgtgatagg ttaaaatcct gccagttgat ctgctggatt gtcttcacat
    13741 gaaacagtcc gacaaccagc aggaaaacag gcaggagtga cgctatcgta aaatgaaaga
    13801 ctaaatcttt accagatggg cgaatccttt taccacgctg tttcatgcga aaaagtctcc
    13861 tttctaccta gcgactattt gtcttgtgtc ggttctttct ttgcttgtgg ttgagctttg
    13921 aatgaactag aatcctttgt cagcacaata tcgtctgcct tgatatacca gtcaacatct
    13981 gctccttgat aggtggcagt agcaacggtg tccgcaatgg gattgataag ttccacccgt
    14041 gcgttataat caaactcttt caaaggcacg ctggcaggaa tacttacttg aatcatgcgt
    14101 ccttgtcctt tggattttaa gtcataggta cgttccttga tttcatctga aaccgacccg
    14161 tcttcatttt ggattctcac ttcacgacgt agagcagaga atttcaattc tccaaaagtc
    14221 gtgtctttat ctaatacaat gccatttgct aatctcatca tttttcctct ctttctttat
    14281 tcttttatca tgtcgtcagc atgtaaaagg taatttgtaa aaccacgagt gccgattttg
    14341 tagccctctg cggtaatacg tggattgact aacttcacac gttcctcaaa gccgaaatgt
    14401 ttttcgccag cttcagcagg aagcaccacc acaatatcat ctgctctttg aacatcagaa
    14461 tagagattat agcttcttga taagacagtt agccgtccgt tgattcttcg ctgaacgact
    14521 ttatcctcgc cagcaaattc taaattgccg aatgtttttt ccatgttggg aatcacaaat
    14581 ttaagttcca tatttttacc tatcctttct tttttattgg ctgaatgaat gtttgatggt
    14641 cttaaagagt ggggaacgac cttttgattc ttgatttttt gttttcataa gttcacttcc
    14701 tttcaaaatc gggtaaaaaa atagacacct cattttttga agtgtctacc tattaaatat
    14761 tcaaatttta ttggaagtat ctttatatct tcacttttca aggataaatc gtcgtatcaa
    14821 agctcattca taagtagtaa attagtagta aattgagtgg ttttgacctt gataaagtgt
    14881 gataagtcca gtttttatgc ggataactag atttttatgc tatttttctc ttaaaaaata
    14941 tcattatttg tggtatggag cccccgcgtt gatccggaag gcacggtaga tttgctcgac
    15001 gaggatcagg cgcatcaatt gatgtggata cgtcattttg ccaaaagaga tctgagcatt
    15061 gcttcttttc atgacggctt cgctgagtcc taaagaaccg ccgataacaa aaacaaggtg
    15121 gctttttcct tggataccta attggtcgat ttgtttagca aaagattcgc ttgtgggatt
    15181 tttcccttca attgctaagc catagacgta ttcttgttct ttgattttcg ctaagatccg
    15241 ttctccttct ttttctttta cttgtctcat ttgcgcttcg cttaaattct ccggggcttt
    15301 ttcgtcagga acttcgatca attcgatttt cgcataggca ttcagccgtt tgacatactc
    15361 attgatacct tggatcaagt atttttcttt taattttcct actgaaataa ttttgatatt
    15421 catgttttct ctcctttgat cttcacgctc actttgttta ttataatcaa ttttttcgtc
    15481 tatatgttta ttttgactat ttttgttaaa aagatttccc caacagttat gcacaacatc
    15541 cacaggttta tccacagaaa acagcgttgt tttaccttat ttcatcacat tcattaggca
    15601 aacatacgtt ttataagaat ttatccactt tatacacagg ctgtggatat gttttatccc
    15661 ttatttttcc aatcctatcc gcgtagtttt acacaatatc tgtggaaaaa gaaaatcaaa
    15721 tattttcatc tgaaaacaat gatttttcct aaagtttttc ataaaaagtt caaagtctca
    15781 aagtagacta aagtcaacaa ataagactat actaacagta gataaatgaa tgtaattgga
    15841 ggaggaacac atggatagaa aaaatgtgac accaaagatg aaaaaaaata aaaataatag
    15901 cctctggcgt aagttgggtc tggggcttgt tggagggatc gttggaggac tactgacagc
    15961 tggcattttt tatgcagcga tgggcactgg caacaatagt tctactgcta caagcggcaa
    16021 tcaaaattct gccggtgaaa cagttgtgga aaatgtcaaa gtcaatgtag attctgatat
    16081 caccaaagcg gtagataaag ttcaagacgc tgtcgtttct gttatcaact tacaaagtca
    16141 aaaccaatca agcggttttg gcggattatt cgggcagcaa gaagaaagta gcagctcaga
    16201 tgatagtaat ttggaagctt atagtgaagg aagcggcgta atctacaaaa aagacgggaa
    16261 tactgcttat gtagtcacaa acaatcacgt agtagatgga cagcaaggtt tggaagtcat
    16321 gatgaaagac ggtacgaagg taaaagctga attagttgga acagatgcct attcagattt
    16381 agcggtgttg aagatcaatt cagacaaagt cgaaacggtt gcctcttttg gggactcaag
    16441 tgctttgaag gttggtgaac ctgcgattgc gattggttcc ccattaggat ctgaatatgc
    16501 gaattctgtc acttcaggaa tcatttcttc cttgaaccga caagtaacaa gtacgaatga
    16561 atcgaacgaa acagtcaata tcaatgcgat ccaaacagat gcagcgatca acccgggaaa
    16621 ttctggtggt cctttagtga atatcgaagg acaagttatc ggtatcaact caagtaagat
    16681 cgcaagtact tctgaatcga cttctaatgt aagcgtagaa ggaatgggat ttgccatccc
    16741 aagtaacgat gtagtgaata tcatcaacca actggaaaaa gacggaaaag tgacacgtcc
    16801 agctctaggt atcacaatgg tcgacttatc tgccgtttct actcagcaac aagaacaaat
    16861 cttgaagatt ccttcatctg taactaacgg tgtcatcgtg acaaatgtcc aaacagctac
    16921 accggcagaa aaagctgggt tgaaacaata cgacgtcatt actaagatcg atgacaaaga
    16981 agtttcttct ggtgtagaac ttcaatctgc tttgtataag aaaaaagtgg gagattctgt
    17041 caaaatcact tactatgaag gctcgaaaga aaaaacaact actgttgaat tgacgatcga
    17101 tcaatcggca ttaaaacaaa atcaaaatag tgaaaattaa taaaaaagag gttgtgacaa
    17161 agacttgtca caacctcttt attttggaaa tacttctccg actacggcat cctcaggcaa
    17221 tactaagatt cctttttttt ctggagcatt tggcaaatgc aattcacgag cagaacaaat
    17281 cattccatag ctggctaccc ctcgcaaagt tcctggccag atcatcattc catctggcat
    17341 catggctcct ggttttgcaa cgacaacttt ttgtccagct tcgatatttg gtgcaccgca
    17401 aacaatttgc aatactgtcc cattgtccac ttctgtctca gtaatcgata aatggtcaga
    17461 gtcaggatgc gggacgcatg tttttacata cccgacaacg atcttcggtt catgatcagc
    17521 ttcaagctgt tcttcgaatc ctgcttcttt aatcaatcga ttcaatttcg ctaattcttc
    17581 atctgttaag cttacttggc cgttcccttc aattgttaga tgatcggaga tatggaaaaa
    17641 gttccaagca acaacttgac cttgttcatc tttgatccga gcaacattcc atttacgttc
    17701 gacagtgttt tctgttcctt tatcgtcggc tatgataacc atcaaagtgt ctccgacgtg
    17761 tgctttgtta taagcaaaaa tcatgttctt tcctccatta tcctttgctg agatttatct
    17821 taacaaaaaa ttgcattcac tgcatgagat ttttttcatg ctttatttcc gaagaagctt
    17881 cttctggaac accatttatt cgtaacaagg gactgtgaca agacttttgt cacagtccct
    17941 ttactgtttg attaaaaagg ttatacaagt tccacttgct taattactcg gctgttcttc
    18001 ttcgtcagaa acgatcaaga catcacaagg tgaatgacgt atgacgtagc tggctacact
    18061 tcctgtcata aagcgttcga ctgcatttag tccagactgc ccaaccatga ttagatcgat
    18121 tgcatatttt tttggcaatt tgactgccat ggattcacga acagagccgt atgcaataat
    18181 tccttctata tttgtgtaat caacagattt tccatattct ttacattctt cgatcatttg
    18241 cttggctgtt tcagtttgct gatcgactag attttgatca ataggagcat agcccataaa
    18301 attataaaat tgctgatcga ttacgtttgc tacatatact ttcccattat tacggcgagc
    18361 cacttctaac gcttttttga aagcagcaag tgcttgttca ctaccgtcaa tacctactaa
    18421 aatgttctta tattcttgat tcatcttgac ccctcctaac agatgtcagc cttttattac
    18481 actttctagg aacgattcga tttcctgttt tgttttacga tctttattca ctagacgacc
    18541 taattctttt ccgtcttgga tcacgacaaa acttgggata ccaaaaatgt tccattcagc
    18601 ggctacatct atgtacttgt cacggtctac ttcaataaat tgccaatcag aaaagtcatt
    18661 ttcgatttca ggcatttgcg gtttgataaa acggcagtct ccgcaccagc cggcagtaaa
    18721 gaaaaataca ctttttccag tttctacgta gcctgctaat tcttctaaac tatttgggat
    18781 aatcattctt tttcctctac tttctgttta tgtatttttc aattaaatta tacacctttc
    18841 tttcgaacta acaaacattg atcctctttt tataaaaaaa atctgacaaa aggttgcttt
    18901 tgccagattt tatagtttca ctatcgcgtt atttcccgta tacgatcgtg ttcactgttg
    18961 atttatctaa acctttcaat gtttgaatca acatttctcg tgcagcttca aaatcgcgaa
    19021 tactgaacat cgtttgatgc gtatggatat aacgtcccac tacgccaatc actgtacttg
    19081 ggattccttc attttgtgta tgagcagcac ctgcatctgt accgcctttt gaaacaaagt
    19141 attgataagg gatgttgttt gtttcagcga tatctagcaa gtactcacgc aaacgaggaa
    19201 gcatgatcaa acctggatct tggatacgca tcaatgtacc ttctcctaaa tgtccgaatg
    19261 tgccattttt cgtcactgtg tcatctgctg cagagcagtc tactgcaaag aacagatctg
    19321 gcttgaattt attgacagaa gctttagaac cacgcaagcc tacttcttct tggacattcg
    19381 cgcctgcaat caatgtatga cctaatgttt cattttgtaa cgcttctaaa gcttctaata
    19441 ccattgtaca gccatagcgg ttgtcccacg atttgctgat gatattcttc ccgttggctg
    19501 ttttgatcgt ttcagcgtaa ggaacgattg tgtctcctgg aagaacaccg taactcattg
    19561 cctcttctct tgattcaaac ccagcatcga acaaaatatc tgttacttct actgattttt
    19621 gtccgcttgt tcctcgtaat aaatgtgggg gaacggaaga agaaatacat ggataattct
    19681 taccagtaga ggttttaagt gtaaaacgtt gagcagaaac aacgtaaggg ttccatccgc
    19741 ctagaggtac gactttaaaa agcccgtttt cttggatttg tgtcagcatg aatccgactt
    19801 catccatatg tgctgcgacc attacacgag gtgcatccgc ttcttcatgg tggcgcagcc
    19861 caaaaatgcc gcccaaacca tctaactgta actcatctac cagcggttcc atatgacttt
    19921 ccatataggc gcgaacgtct tgttcaaaac cgcttgttcc ttgtaattct gttaactctt
    19981 tgattcgttg aaatgttttt tcttccatat gctattcgtc taaatttcag actaaactcc
    20041 tctcagactt atattgatct gcggataaaa tatgattttt tctgcagacc gatcgtattt
    20101 attatagctt attttttctg gtagcggtta tttatttcaa agaaaatatg agagtgtggt
    20161 aaaataaaca caaagagtag caagtgagaa gaaggaggta tatccacatg tatgaagaaa
    20221 gcgaattaag ctattttaaa ggcgggttag ccgttgggat cggtctagga ttattgagtg
    20281 gggtagcttc aacgatttgg tatcatcgca aaaaagtgtt atcagcagac caagtgcttg
    20341 aaaatatcaa aacatctttt ttaaaagaag gcgcaatcga aggtgcttgg atctcttttg
    20401 aaaaagaacc tattcggaaa ttcgccgttc ggtcgagtgc ttatcggggt gggctttccc
    20461 ggatagaaga tggcgaaact gtttattatg aatttttagc agatgctcat acaggaaccg
    20521 tattagacat ttcaagaaaa aagggcgcaa tagattaata cgtcaaaaaa atgaaataac
    20581 gaatacgcac ccactatcta aaagagaggt atcctatcct tcttttatag tgggtgattt
    20641 ttataaaaat agggctattt cctcttggaa tagctagtat ttgtagttat tatacggtat
    20701 tcttgaaata agattagttt tattatataa ggagagtgac aaatggaatc acgtgaaaaa
    20761 attgccgtgc tcattccttg ttataacgaa gaggcgacaa tttcaactgt tattgaagat
    20821 tttaaaaggg aattaccaga agcagatatt tatgtctatg ataataattc gaccgatcga
    20881 acatacgaat tggccgttca aggcggagca atcgtaaaga aagaaccacg tcaaggaaaa
    20941 gggaatgtaa tccgtcaaat gttttttgat attgatgccg attattattt gatggtagat
    21001 ggtgatgata cttatcctgc agaagctgca catggtttgc ttgagaaatt acgttctggc
    21061 gaagcagata tggtcattgg cgatcgtcta tcaaatggaa cctattttga tgaaaataag
    21121 cgtcctttcc atgattttgg gaataatctg gttaaaaata caattactta cttatataaa
    21181 acaaaaattc gcgatgtcat gaccggctat cgaggattca atcgaatttt tgtcaaaagc
    21241 ttccctatta tgagttctgg ttttcaaatc gaaacagaat tgacgattca tgctttagat
    21301 aaaaaattca agttcgttga gattccaatc gattatcgcg atcgtcctga aggtagcgaa
    21361 tcaaaattga atacattctc tgacggattc aaagtgatca tgatgatcat caaaatgtgc
    21421 aaagattata aacctttgct tttctttggg atctggacca tcttcttctt tttatttgga
    21481 ttggtcatgg ggattcctgt gattcgtgaa tatatgctga caagctttat tacacgcatc
    21541 ccttctgcga ttttaagtac tggattgatg actttagccc ttctttcatt agtaacaggg
    21601 ttgattttgg atacggtcgt cacaaatgcc aagaaagaat atgaattgaa tttataccat
    21661 gtctaccacg aatatcaaaa taaagaaatg aagtaggagg ccttttttat gcataagaaa
    21721 aaggagaatc tatttcctac tttttttgca actttatttg cgtcaggttt tgcttttttt
    21781 acttcttatg gtctaggaac tttgaatcca acagtaatca ttggtttagc catggttttg
    21841 ctacttgctt ttaagcaata tggaatagag ttgttttcaa taaaaaacaa agttgcagct
    21901 attgcccgat tgtttttttc tgcagctttt gctcttacac tttctattgg cagacagata
    21961 caatttcagt atgtctcagc aaactataca aagacaacga ttgctgatgg aagtattttt
    22021 tactttcttg tttatttctc catttttgtg tattcttttt tatttttaca atcgatttat
    22081 ttatcaatgc caaaactgga aacatttttt actgctcaaa acacacaggc tttctcttca
    22141 agaaaatatt ttttattctt tactgtcttt ttagttctgt gttggcttcc ttatctgttg
    22201 gcattgtatc ctggagtggt tttgcctgat tcgttaagtt cggtcgccca atctatgggt
    22261 gatgttccta taagcaatca tcatccagtc ttattcacct tactggtcaa gctatttgtt
    22321 catgatttac caactgatac gatcaatcac ggtgtatttt tattttcgat ttttcaaaca
    22381 ttgataacag cttcagcgat aagttattct ctttgctggc tgttaaaaag aaacatccat
    22441 ttttttccgg tactcattag tttatgctat tttgcatttg caccggtttt tccaatctac
    22501 gccttgaaca tgcaaaaaga tactttgttc tctatcgctt gctttttatt ttccttagcg
    22561 gtttttgact ttatttttca acgagaaaag ccaacgattc tcaatcagat ttacgtaatc
    22621 atccttgctt tactgaccac ctatctaaga aataatggga tttatgtagt aaccggcaca
    22681 ggtttgattt gcggcttgat tattttgaaa caaaaaaggt atcaagcatt ctttcaagtg
    22741 gtgctgggtt atacagtgat tgctggacta ctcatccacc cgttgatggc tcgttatgct
    22801 attcctacag aaactgctga acaattaggt gttcctttgc agcaaatttc tagaactatt
    22861 gttatggatg gtgacttgtc taagaaagat aaagcattca tgaatcagct actcccgata
    22921 aaagattatg aagcgtattc tcctagtctt gcagactcaa tcaagtggca taaaaatttt
    22981 aacaatgagt ttttgaatac acataaaaaa gaatttctat cactatgggc aagaaattta
    23041 ccaagtaata taaaaatcta tacagatgct tatattttag aaacgttcgg gttctgggta
    23101 cctggtacaa aaaatagtta cggcttttta gatactcgtg taaacacgaa taattatggt
    23161 atgaagcaag tagatttgat tgaacatctt actggattgt caggaatgaa aaaaatcatc
    23221 gatgctcgtg atttctttgg ttccggcaca ttactgtggt tagctatcgg cagtgcactt
    23281 ttagcaatct ttaagaaaaa atatcggtat ttactccttt ttcttcccgg tatgcttgtt
    23341 tttgctacta ttatgattgc tactcctgtg gcttttagtt tacggtatgt gtttgtttta
    23401 gcattaggtc tacctgttta tatcctctct ccttttttac tagataaaag agaaaaaatg
    23461 aaaacagata taggagatac tcatgaaact atttaaaaag atattttttg cttttgttct
    23521 cttgatcgct agctattgcg tactactgac aattactttt ttcattccgc agcactctat
    23581 tgaatcgaat gcagaaaaat ctctacagat ggttgaaaaa gaaggaatgt atccttctat
    23641 caatcaagga aatatgctag gcactcggtt agataatttt actgatcatt tgatgatacg
    23701 aaaaacaaaa gcagatcctg aattgaactc cttggagaac gcgatgtcta tggcggatta
    23761 tccccgttat tggcatggtt atcagctttt tttacgacct ttactgctag ggatgagttt
    23821 ggggagtatt cgaatgattt acgcagccat tctttttctg ctgattggat tgacgagcta
    23881 ctttttaacc aagtgtagcg acatctattt aacgacagcc ttgttgattt cgcttgctat
    23941 aggaaatgct gcaacctttt tcttcagtat gcaattttca aatatttgga ttttgacttt
    24001 attgtctgta ttactatttt taacaaaacc acaactctcc aacaccaacc aacaattatt
    24061 cttgtatttc tttgtcattg gttctttagc taactttttt gacttgttga caacaccggt
    24121 catctcttgg gggatacctg tgatcattat ttattatgta acaaataagt atttaatgga
    24181 taaacgcagt tcattgagca aacaagtagg cagttttgtt tttaccggta tcttttgggg
    24241 attaggctat ggtttgacat gggtggctaa atggatccta tcatcgatca tattgaacaa
    24301 aaacattgta aaagatgcaa tcaaccaaat cctctttcga acggaaggaa acgacaaata
    24361 cccgttgcat cgattagaga tgctgaaaag caatattaga ttgatgtatc caaaagtagc
    24421 aatattattg ctattgatta cttgtcttgt ttttctctat tttgcttatc gtaaacgaaa
    24481 tagctggcgt ccgttccaac ttctagtttt gtttgtttta gctgctgtaa cgccgtatat
    24541 ttggtacaat attttagcta atcactcaca gattcattat tggtttacgt atcgtacgca
    24601 aatcatcaca agttttgcta tacttagtgc tttcgccttt ttgatccctc ctgagaaatc
    24661 aaaagacgaa ctaaattact tttaagaata ccgatgtact aattcatttt taaacataaa
    24721 aactccagct gtcagagata gccggag
//
LOCUS       DADVXM010000035        24188 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.036, whole genome shotgun sequence.
ACCESSION   DADVXM010000035 DADVXM010000000
VERSION     DADVXM010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.036"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..1643)
                     /locus_tag="KB927_001489"
     CDS             complement(<1..1643)
                     /locus_tag="KB927_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBB6840413.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKCFLAMIDEC"
     gene            complement(1806..2399)
                     /locus_tag="KB927_001490"
     CDS             complement(1806..2399)
                     /locus_tag="KB927_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840414.1"
                     /translation="MRVKGQNSVDRKSILQFGKPEERSILDLFPYKSCTEEGVLITKE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            complement(2400..2732)
                     /locus_tag="KB927_001491"
     CDS             complement(2400..2732)
                     /locus_tag="KB927_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840415.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTIGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            complement(2826..3296)
                     /locus_tag="KB927_001492"
                     /pseudo
     CDS             complement(2826..3296)
                     /locus_tag="KB927_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3357..5717)
                     /locus_tag="KB927_001493"
     CDS             complement(3357..5717)
                     /locus_tag="KB927_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840416.1"
                     /translation="MIIGGIFSGIADWWSGLFGDGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLENDPNKVEHIPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKIIGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNVAKNVGSGAKNLASAGKSGLSNLNDIRKNGFGN
                     RKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTAE
                     DLTEKAKDTLEEKLDGTRAKELAEAVKNPSETLEKQKEKASEVKEGLKDAYGEGQVNA
                     AVKANTTTEKENQEGAAIPSAKDHQDELHSNENSEEGQNGQLPKTDPEQYRYKSNINS
                     ENEKRISDLPKRNQEVQTDDDSIDLPNDNGVEVGTEKSTKNGLPKAQNLPMKDSRLNQ
                     FKENDQSFVHQSTAGNVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAP
                     EPIQKVHTGYKPANVAFTAPTKINVTRDTKNRNNALKEQLLKDIKP"
     gene            complement(5714..8323)
                     /locus_tag="KB927_001494"
     CDS             complement(5714..8323)
                     /locus_tag="KB927_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBB6840417.1"
                     /translation="MRVRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGGFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYQDPDNEFKQLNALDEFMNQLPPGNTAKKQYGATKIGSDKAKGNIL
                     STAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKK
                     FHEERVKVGYRGFCEINFDCHLEQGDHVCLKYDHRGKEYVAWYEFSQRVLKDEEGNIV
                     YRKKRGETHLPELEKEAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHII
                     VSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLW
                     DLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENST
                     INSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNHG
                     ETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDIYARRLYHNMH
                     DQIEEEAKENIFIKIVQSLDNSTAQKLLIQFYEEKQIDRLQEYLEKLRQNEEITEVIR
                     KRLLLEAEKAVKE"
     gene            complement(8323..10386)
                     /locus_tag="KB927_001495"
     CDS             complement(8323..10386)
                     /locus_tag="KB927_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840418.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGQLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDPSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            complement(10456..10758)
                     /locus_tag="KB927_001496"
     CDS             complement(10456..10758)
                     /locus_tag="KB927_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840419.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            complement(10776..11018)
                     /locus_tag="KB927_001497"
     CDS             complement(10776..11018)
                     /locus_tag="KB927_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HBB6840420.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            complement(11015..11479)
                     /locus_tag="KB927_001498"
     CDS             complement(11015..11479)
                     /locus_tag="KB927_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840421.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            complement(11506..13596)
                     /locus_tag="KB927_001499"
     CDS             complement(11506..13596)
                     /locus_tag="KB927_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBB6840422.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKTTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            complement(13593..13853)
                     /locus_tag="KB927_001500"
     CDS             complement(13593..13853)
                     /locus_tag="KB927_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840423.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            complement(13866..14627)
                     /locus_tag="KB927_001501"
     CDS             complement(13866..14627)
                     /locus_tag="KB927_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840424.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLFSDQLKLVSNGKTKTIDQQT
                     GVFEFSIEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            complement(14643..15395)
                     /locus_tag="KB927_001502"
     CDS             complement(14643..15395)
                     /locus_tag="KB927_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6840425.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIVAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWTWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            complement(15410..17386)
                     /locus_tag="KB927_001503"
     CDS             complement(15410..17386)
                     /locus_tag="KB927_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBB6840426.1"
                     /translation="MAINRYVKKAGMLVGMLGIIASCFQGYQAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGAGGITVNGVKSETSPYSVFKWGDIA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGIGIKATPLEGAEFAAKNAEGKYYGGLVDTDKNGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            complement(17439..18113)
                     /locus_tag="KB927_001504"
     CDS             complement(17439..18113)
                     /locus_tag="KB927_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBB6840427.1"
                     /translation="MDEKMVIFFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKIPV
                     DQINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIF
                     KGTNQYTLSLGAATYFYEDGEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSN
                     DGVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYV
                     VQGELQ"
     gene            complement(18191..19353)
                     /locus_tag="KB927_001505"
                     /pseudo
     CDS             complement(18191..19353)
                     /locus_tag="KB927_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
     gene            complement(19359..20048)
                     /locus_tag="KB927_001506"
     CDS             complement(19359..20048)
                     /locus_tag="KB927_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HBB6840428.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGHQKDKIAEKVDGVTK
                     TIHIQEQDKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYPDAEMGNGNYILAGYNVDTPSVLLSDMIDLSEGEEIDLIDA
                     HYKYQYEVSKRGKIYDYSQVVQSKENNSFLSLPKAGKKPLLTLLDFEANNMKKCDVIQ
                     CELVNVEKINK"
     gene            complement(20175..20369)
                     /locus_tag="KB927_001507"
     CDS             complement(20175..20369)
                     /locus_tag="KB927_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840429.1"
                     /translation="MEEKLLKTMKQKHLKRLSVMQYISDMQITGKEKACLLGSMKNFE
                     QLRRTYVKIRSNCQLLLEVS"
     gene            complement(20479..20718)
                     /locus_tag="KB927_001508"
     CDS             complement(20479..20718)
                     /locus_tag="KB927_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840430.1"
                     /translation="MARPVLDAMDMDTLTKGRYVQLLARSYSPKDVFKALSKGTDMEK
                     ERLRKEFDYWRIYNGIKDLKPARPVVKRKKKITQE"
     gene            complement(20885..21226)
                     /locus_tag="KB927_001509"
                     /pseudo
     CDS             complement(20885..21226)
                     /locus_tag="KB927_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
     gene            complement(21845..22177)
                     /locus_tag="KB927_001510"
     CDS             complement(21845..22177)
                     /locus_tag="KB927_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBB6840431.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            complement(23002..24042)
                     /locus_tag="KB927_001511"
     CDS             complement(23002..24042)
                     /locus_tag="KB927_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBB6840432.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYE
                     SSPSTITKDWLE"
BASE COUNT         6773 a         4834 c         3716 g         8865 t
ORIGIN      
        1 tggcactcat caatcatcgc caagaagcat ttgaagtctt gttcttccat ttgtttttct
       61 ttaattaaac gtcgttgtct tcttccttga atcaatgcct gattccaaat caacgtcata
      121 gccatgtaca tttgacattg ttgtacccca cgatctaaac ctgtaataga gtcaatgtca
      181 aaaaagacca actgttgttg gtcaaggtgt cgaatcgtac tatgaccatc aaaaatcatg
      241 ccatacgtct cacataagga ttctacgatg gattccattt cttcttttcg attctttttc
      301 tcttgggaag cacctggtaa ttccagttgt cctaaaaagt ctaaaaattc tttgaacgtc
      361 ggataagctt ctggatcttt ccctgtgact tgcgtctccg tatttgaacg cgagtttgag
      421 gaagtgaaac cgcgtggtac tgttccatac tcttcataaa aacgatttaa ataggtctta
      481 aattctgctt tcatcgttcc ttttagctga ggactcacta actgtacctg atagaccact
      541 ttgtctaagt gcgtttgata ggacgctgct tcattgatct tcaaatcttt gactgatcca
      601 tcgtcatata aactggaagc ttcatcatac gtacgtgtgg caaatatttc taaaggattg
      661 atcatcccgt cagatccgtc taaacgcacc ataatgccgt tatattcctt taaaaaggga
      721 ataaagtctt ttcccttttc aaagccccaa ataaagtctc ctgcagctaa atgggcttcc
      781 gcgatcattt taagaacggt cgatttacca gctcccatca ttcctagaag caaggtattg
      841 gtagacaacc gcacactatt tttatacgtg gcattccaaa caaacgggcc gcctgtcatg
      901 gtttccccat attgtgttcc acctggatct tttagcgttt ggtggtggaa cgggaaacct
      961 ccgccaatgt ttagcgatgg tagtgattgc cctttgatat ttccaaacca ttcagcttgt
     1021 tcatcgaaca tggtgaacat cgattgccag tctcttttcg ttttgtgcag ataggtcact
     1081 gcacgataat ccatcccttt gagattttcg atcagttcct gtgctcgttc atctacttct
     1141 tgaatcgtgt ttccgtaaac atgtactctc actttgactt gtttagaaat ttccccatta
     1201 gaagtcaatt ttcgggcata ttccgctagt tctaggtatt cttccgcgct tttatttcgg
     1261 tcagtcgctt ttcgttcatt atctgaccga tcatttaatt catctaaggc acgattgatt
     1321 tgatcaatca ctttttgctt ttcatctgtg ctaacatcta gtgttgccac tgtatgagga
     1381 ttgttcatga gattggccaa ccaaaaaagc gtaggatttt ttgtgtagtg ataaactgtc
     1441 acacatcgtg aataaccatt tccataggtc acatactctt catcgaaatt taatccacct
     1501 tgtggcatca cttgttttaa aaagtctaaa tcataccctt tggattttaa aatttctatt
     1561 tcccgatttc ctagttgctt taatggatca agtacctttt gatcattttg tggtgaaaaa
     1621 gctgttttaa ttgcttctaa catgtacagt cacctcttct tgtttgattc tttacttggt
     1681 taaaagattt tccttttccc aacttaccca ggcttaaagt gtgaggaaat tttctagtgg
     1741 tctcttcttt cggaacatct ttttctaacc atatcaacgg atatttcatt ctctcttccc
     1801 cattcctact catcattcat attattcatt cgataaagaa tcttgatcaa ttcttttttg
     1861 tagagtggtt ttaaccctaa aatgccacta gatcgcatta actgacggtt tctggtttgc
     1921 aaatccttga ttgtctttcc ttcaatgacg aaaaagaagc ttaaatcagg gcgttcctgt
     1981 tctgctcgtt tcaattcctg gatttcctct actaatttct tttcatattt tcttaatcgc
     2041 tgtagatttc ttcctaagga ctgttccata cgatttttat ctaataactg ccgcttttgc
     2101 acgatttgct ccgttagatc cgtttctgtg gtcaaactaa ctaacttaat cgttggcaca
     2161 tacgtacgca tgacagtggt caactgattc attcgttcca gtttctcttg ttcatttaat
     2221 ccttccacat ctgtagaaac tacacgataa taacgttgaa aatgatcttc tttagtaatt
     2281 aagactccct cttctgtaca ggatttataa ggaaataagt ccaagataga gcgctcttct
     2341 ggttttccaa actgcaaaat ggattttctg tcaactgaat tttgaccttt gactcgcatt
     2401 tattcatcct ccttatacgt accatgataa tttcggttag gatctaacgc atgataatgg
     2461 ttcttgtccg taaaaaaaat agactcgata atcgcaaaaa tctggcgttg acctgggtta
     2521 ttatagggtc gccaaacaat cactaaagct atcgcaatcc ataagccata attcaagagt
     2581 gcaaaaaaga gtggtaagtg gacaagatta ttgactattt tcgcccaaaa aaagcaacca
     2641 ccaatcgtta atagatctaa aaagaaaaag gcgaaaaact tccattcccc actaaatctt
     2701 ggtggatttt tcatatgaat gtatttatcc ataatgtaac catactcctt atgttcttta
     2761 tttttagaaa caaaaaacac tgtgatttct cacagcgttt ttctaaatat tataactcta
     2821 attcaatttt cttcttttaa ttcaaaaatt ttttgttcta ggtttctttt catttgaatc
     2881 aactcataat tttgtgcgcg taattcttcg ttttccaaat gaactcgttg catttcatcg
     2941 tttaatcgat ttaaattctc caatgattct tgtatcgttt cttgcctaaa attaagtgag
     3001 ccaagttgac gatctttttg ttgtctttgc tctttcaatt ctgacgatat ttgctcaaca
     3061 gaatgaaata gctccgttaa ttttactgtg aatgtgggca tagcatcttt caaataagtg
     3121 aatccttctg aaaggtgtac aataatgctt tcggtatgtg ttttttgacc atctaaaata
     3181 gactgatgat ctttttgtaa actctccgta tctttaaatc ctttaatagt cgccacaaat
     3241 atcgttaaaa atgctcccag tgcagttata aacgtagcta ttaaaatatc ctccacaatt
     3301 ttctcctttc cattttaaac ttgttttata aagaaaaagg cccttaaata ggccttttat
     3361 ggtttgatat ccttcaatag ttgttctttc aatgcattgt tcctgttttt ggtatctctt
     3421 gtcacattta tttttgtcgg tgcagtaaat gccacatttg ctggtttgta acctgtgtga
     3481 actttttgaa taggttctgg tgcagcttct cttgtcacaa cattttgaac ggacgcattc
     3541 cctgtctccc cactttcaga taaattgtaa gaaacagttg tcagatttcc attttcaggc
     3601 aaacgacttg gtttcatttg aacattacct gcagttgatt ggtgaacaaa gctttgatca
     3661 ttctccttga attgattcaa acgactatct ttcattggta aattttgtgc cttaggtaaa
     3721 ccatttttcg ttgatttttc agttccaact tcgaccccat tatcatttgg cagatcgatg
     3781 gaatcatcat ccgtttgtac ttcttgattt cgttttggta aatctgaaat gcgcttttca
     3841 ttttcagaat taatgttaga tttataacga tattgttctg gatctgtttt tggtaattga
     3901 ccattttgtc cttcttctga attttcgtta gaatgcaact catcttggtg atctttggct
     3961 gaaggaatcg ctgcaccttc ttgattttct ttttcggttg ttgtattagc ttttactgct
     4021 gcattgactt gtccttcacc atacgcatct tttagtcctt ctttgacttc tgaagctttt
     4081 tctttttgtt tttctagtgt ttcggatgga ttcttcacag cttcagccaa ttctttagct
     4141 ctcgtgccgt ctaatttctc ttctaaggtg tctttggctt tttctgtaag atcttcagct
     4201 gttcctttta acccacgttc attgacgtaa ccaagacctt ctgcggcttt agaaacacca
     4261 tttttcgctt tcccgaacat ttcggaaact gttttcttac tattaggtac agttgtagct
     4321 ttatcgtctg attgttcttc cccgttatca ggggtaacat cttttcgatt accaaatcca
     4381 tttttacgaa tatcatttaa attgcttaaa ccactcttac cagcacttgc aaggttttta
     4441 gccccgctac ccacattttt cgcaacattt cctaaggcaa acatgctaag aagagaattg
     4501 ctgccgtttt tcagactcgt atcaacgccg aaaattttcg taactgattg agagcctttg
     4561 aatagcgcaa tggttaatac aattaaagcg acaacataca agaatccaat gatctttcct
     4621 gccgcatgca aatcaccgat acctgaaagc attaatgtat agattcgtaa ttctaaaatc
     4681 gtaaatgcca ataacaagaa ggattgagaa atatcttcta tagcactttt catccgttgt
     4741 cctgtctcaa agtccgttga cgcggcaatc actaaataga attttttaaa taccagctca
     4801 ataatgcaag taacaatcgt aaacaagata aataaatagg ctaccgacaa agaagattca
     4861 ccagctaaaa taatacctgg actactaatg tatcggcgat agcctgaagt atacacatat
     4921 tttgctaaac cttcatcact aatttgaaca gggatttctt tcccattatc gtctaactct
     4981 agtcgatact gtaatgcctt taaccgatct ttttgtactg tactaatatc acttgattca
     5041 gacattttct tagcttgatc aggtgtaata atcccattga tattcgctgt tttaaaattt
     5101 ttcgccgtga gagcatttct tttgtctgtt ggtatgtgtt ctactttgtt cggatcattt
     5161 tctagtaacg tactcacatc aatcacatta ttttgaataa tttgaaaagc aggtgaacca
     5221 gttttatctg ctttatttgc tgcagtcacg tctccgtaaa agtttttact aatatttagc
     5281 ccttcatcga ttaaagaact accaccaaaa atcaaaatca tggccataaa tagattaacc
     5341 aagatatttt tgatttttgg tggatgttta ctcataaaaa attttaagcc taaataaatt
     5401 aatgtgacga cacaaaaaag agccaatacc ttactaatca aactttgaaa cagttcatta
     5461 acaccagcgg cgttcaataa gtcttttaaa tcaaagcttt gataaattgt tttttctagt
     5521 aaagtattga gattatataa ccctttaatc aaaccccata aaaaagtatt acaaatccaa
     5581 ctgaatacat cttgatactg cagataatta ccataatctt gtaagacttt cgttacggtt
     5641 ttgggatctg catccccatc cccaaataag cctgaccacc agtcggcaat gccggaaaat
     5701 attcctccaa tgatcattct ttcaccgcct tttcagcttc tagcaaaagt cgtttcctta
     5761 taacctctgt aatttcttca ttttgacgca atttttcaag gtattcttgc aaacgatcta
     5821 tttgcttctc ttcataaaat tgaataagta acttttgtgc cgttgagttg tctaaagatt
     5881 gaacgatttt aataaaaatg ttttctttag cttcctcttc tatttgatcg tgcatattgt
     5941 gataaagtcg acgtgcatag atatcaggta gaaaataatc gtaatcaatt tgtaaagcct
     6001 taagatccaa gtccgcatgt gtacaatgta tgtctatatc attgatatcc cacgatggat
     6061 tgaaatcttc aatatattga taagcataag gaagattcgt ttccccatga ttaaaaatag
     6121 gatacggccg tattttatga cctttcaaat cttgtcgttt taaaggagcg agtacaatcg
     6181 tttcaccttc taaaaaagta gaaattcttt caggagttaa gatgcgatct gaatcaacat
     6241 tgcgattgat atgagtattc atacctaatg aattgatggt actgttctct tgttcaaccg
     6301 tcttattccc cacttttttg gaaaattctt ctatggtatt atcgtctgtc gacataatat
     6361 aaatatgtgt ctgacaattt tctttgataa tcgctgcgtt ttgttcccca tacttcgcat
     6421 aaagttgctg ataggattgg ataaacaaat cccacaacat gtttctacca gctgtgactg
     6481 tcatgattcc ttccatatta tccattggtg gcatattccc aaattcatct aaaataaaat
     6541 gaatcctacg gtgacattta tctcctttag tcttaacaca ttgcgtagat aattctttat
     6601 acaactgact aagaaaaata ctaacaatga tatggttaga tggatcataa tcaggtgtga
     6661 gcataaaaat agccattggt ttatcggtat agtgcatccg aatagactct actaataagt
     6721 tacttttatc ctcatctaat gttagaacgg cttctttttc taattctggc aaatgggttt
     6781 ctcctcgttt ttttcgataa acgatatttc cctcttcgtc tttcaatact ctttgagaaa
     6841 actcatacca agcaacatat tcttttcctc gatgatcgta ttttaagcaa acatgatctc
     6901 cctgttctaa atgacaatca aagttaattt cacaaaaacc tctatagcct actttgacac
     6961 gttcctcatg aaattttttt ccttgatgat aaaactctac aacaattcgc tggtttaaca
     7021 gactctcgtg tagtttgaga tccaaatact tcggaaaacc aatggactta taatcaatgg
     7081 ttgattgaga agtcattttc gcaattttcg tcagtgtaaa tggatttagt cctgtgatcg
     7141 ctgtcgatag aatgttgcct ttcgctttat cagaaccaat ttttgttgcc ccatattgtt
     7201 tttttgctgt gtttccaggt ggtaactgat tcataaattc atctaaagca ttgagctgct
     7261 tgaattcatt atcaggatct tggtaattaa aaccaccaat ctcagaaaga agttcgacga
     7321 gattattcgg tgttaatttg gagtaatccc ctgtctgatc cgcttgttcc aataacgcaa
     7381 aaataagcgc attgacagct ttttgcgcat tttcgttaaa gtatttattg tctgaagcgt
     7441 tggcatcata ataaatcgta ttcgtgaaag tattggttaa ctgtgtcgct gtgtctatgt
     7501 ctcctcgctt ccagtatttc acgatgagtg ccaatggatt atcactcatt gattgcagtg
     7561 gatcggtgat attaaatgca tacacatcat accctctagc ttctagttca tctttactag
     7621 caacatataa ttctgttttt ggatcattaa caaccattga actttgtctt tctgcacgag
     7681 acaaattgtc aatggttgct aaaacttcta tctgtccttt ccctgaacgg gaagtaccaa
     7741 caatacaagt atttactgta tccgtctgaa tataccagta ctttttataa tgagtaattg
     7801 gtattccgcc ataaccagga aaacctccct ttgattctgg tatttgcgga taaatttgtt
     7861 ggatttcctt taacgttttt aatcggttat ctcctttttg cccatctgct agaggacgaa
     7921 accacatgtc cattttcaat cccataagta cagctggaac aacacaaatc gtagaaacaa
     7981 ctaaacgtgt gcctaaactt gttgttgggg tcaaaggatt ccaaaaacca gttgaatcaa
     8041 aatggaataa ctgcggcatt tcttgtaact gaaaaatatt cactccttgt aaacttcctg
     8101 gaataatctc aaatcgatga aatgcttctg gtattcttgt aacaacatag tttaaaggaa
     8161 gataagctaa gccactataa aaaatctttt gagaaatacg tttgtcatgt ttttctggta
     8221 gctcttctcc tgaaggagta tagcgataga aatgagaaag atacctattc ttttctaaat
     8281 tgaatcgttt gtcttttcgt ctcgttgttt ctctaacacg cattatttca cctcatttga
     8341 ttctgaactt tcggaagtgt ttgattgtac agttgaatcg cttgatcctt ctttagcctt
     8401 actaggatca ctctctttgc tattttccat acttgattct gttgttgact gattggtacg
     8461 attcaataat tcttctaatt gttgttcata ctcttttctt gcttgttctt gggcttcttc
     8521 cttgattgac gtcgttgtgg ccacagaatc agcctgtgaa gattgattga tatgattaaa
     8581 agcaaatact gttcctccac ctagaagcaa gcttaaactt gcaatacatc ccaccatcca
     8641 tccgttaaag gaacgctgtg gtgaaggagt tagatttgtt tggttgttca ttggggtttg
     8701 aacagcagct actgaaggcg ttggttgagg ttgtgctaga taatttaact gagcttgtcg
     8761 caatgtatcc atttgttctt gacgttcctt acgagcagct gcttcttttt ccttttcttg
     8821 gtttaaccgt tgtttttcta ttgccatttg ttgttccgca agatcctgtt cacgtttttt
     8881 tagttctaat tgttcgcgct ctttttcttt ttgccgttgt ttttcttctt gttctttcaa
     8941 ttcttgttgt tgaatttcat actctttttt ccattttgga atttgcactt gtaattcttg
     9001 ctggatcttt tcgtgttttt ccataagaac ttcagtcgtt gtttgatata gcttattcag
     9061 ttgttcattt aattctttgc taatctttag cttatctgta cgcaaacctc ggtaaaattc
     9121 ttcttttcgt tctttaatac gttcttttaa caagttttct ttttctttcg ataacgcttc
     9181 ttgattcgtc tgagtaaaat tattgatctt tgctacacac aaggaatacg cattgtcgcg
     9241 tttcttttcg tatcgctctt taattttttg tacttcttct tcaatcactc gctgttcttc
     9301 tttatttagt tcctcttttg ctttctccca attagacgac tgttccgtcg catactcatt
     9361 aatttcttga tctgtttctt gttgacgttc ttcaaaggtg gctaataaat cttcttgtgc
     9421 aagctcatgc caatttgttg attggacaga ctctaactgt tctaaaagtg tgcctttacc
     9481 ctgtgagatt aattcttctt tactctctaa aaatgcttga taggtttggg gtaattgata
     9541 tttcgaataa agctcattta aaaataattt gtttttttct ttcatccatt catgctctgg
     9601 cggatattga tccaaaatat aatcaaatac agttgccttt tgtatctcta tttcgttttt
     9661 ttctacttct tcactgataa gtggttcaat atattcctga gaatcccctt cagtccatgt
     9721 tgactcttca ttagcttcaa ctggatcaac ttctacttcg gccgtctctt catcctccat
     9781 tgtttcttca aagggatcta cctccaattg acccatcaca tcgttctctt cctcaaatat
     9841 cgatttctga gtcggaatat cagcttgttc gtcaacatag actgtctctt tttcttttga
     9901 ctccttcttt ggaaatattg gtcgttccca tggtacttct tcatttactt cgacttcact
     9961 cccttgattc acttttcttt ggtcgctctc taactcttct tctaaaactt gtaaaagttt
    10021 ttcgtttcga taagactctt ccacactcat agtttcatcc gtttctttaa acacatcaag
    10081 gcggattaaa tccatcaatg taggatagaa accttctgaa atttgataat ccagttgccc
    10141 aaaaacgtat tctgtaccag ctttctctat ttttccttct gtgtcatgta acgtgagagt
    10201 caacttaaca gaagatcgac tttcgtgttc cagtactttc cctaacacat gtagctgttc
    10261 ttccgtttca atgacagaat atttaattgt tttcggtaaa aaagaagtac gctttcctac
    10321 ttccttcgtt gcttttttta ttaactcttt atctgttttg gtattgcctg caatcgtaaa
    10381 gtacatgagt attctccttt cataaaaaag gagtaaaaag tatcgactac ttcttactcc
    10441 tactttttta ctttcttata atccttgagg tgtttgtcca aacaatccaa ataacgaaac
    10501 cacaatagaa gctgctgcta aaataactcc tacccccatc aatacatagc ctacgtgcat
    10561 cttcccattt tcagctcctc ttcgtccaaa taggaagaaa agacccccaa taacaatgga
    10621 agcaacggcc gcagcagcag caaaaatcat cagattgttt tttaaactag ttgcggcagt
    10681 ttgtaatgct ctaaaaatat caaccgcagc tactactttc ggttgtgtta aaaaattcat
    10741 tgtaattgat tcaaacataa aattgttcgc tccttttagt gtttaataat ttcgtcgaaa
    10801 acaagctttt cacgttcacg ttgatagata tatccttcta agtccttgtc ttttccccgt
    10861 aataggtcaa attgtgcttt ttcaaggact tcttgtttcc actgtgtttc agatacaccg
    10921 cggcgttcta agattttaga cgcggctttt tcaaatggcg ttttagcttt tgccactgtg
    10981 attcctcctt caggacaaat aaaaagacta gcaatcactc gctagtcttt tgtaacttat
    11041 atttattgga ttgtgatcca tcgtgaatca atttctcttt cgttcgcttt tcatccttgc
    11101 tagatccaag aaaaattatt ttttttacgc cattcttctc atagggaaca acaataaata
    11161 aagaatcaga tttgtttata aattccctaa caccagctga atctactatt ttgtatcttt
    11221 ctaaaccttt atagtctttt tgcctcttga ctgttatttg tacaggatct ggatgccata
    11281 cactctcaga gtattcccag gtagtctcgt ctataatttt caaattataa acaagaccac
    11341 ctacttcttc tttccacata gttcctgatt tcaatacgcc attatcttga ttagtttgtt
    11401 tatttttttc attactacat ccgactaaaa taacaatcat ggcaatcaag gaagtaacta
    11461 ctattattaa ctttttcatt ttattcattc tttcgttttt ttattttaaa tgtatctcag
    11521 aaccgcataa ctaaaagttg ctaacacaag taatagtaag ctgaccgctg aaatcgttac
    11581 taaatgtgta gaacctgttt taggaacaat gacctgtggc aagttaggat caaccccaat
    11641 tgtcacaaca tttgttttat tagaaacatt atctactgct actacggctt ggttatcaat
    11701 atttttttct gattgtaatg gagttttagc tgtaaatatc agctgaattt ctcgtccatc
    11761 taaaagattg ttacttaaga agtcagcgga agcttcccac ttcagcgttc ttgaattgct
    11821 atcataggtt agtgtgcctt cagaagtaat atcttttcct ttactcttat ctattacttg
    11881 cgcagaacct tctttatatg tcaaacgagc ttcaattgga tcttgaatac taaattgttt
    11941 gtagtgatct gacgcagcgt ctacgccttt tgtgtgccat ttttgtgtga ctagatattg
    12001 tacttcagat cctgcgttta aaggagctgt cggcgtaccc ttcttaccgt catttcgtcc
    12061 gtttacatct tttccatttt gttgtacttc tttcactgga attttaggga aataaacggt
    12121 aatgatattt gtatcctttt ctactttatt aatgatcgac gttccctgat ttttggctac
    12181 actattttga ttggccaatt cattgacttt tacattgatc actaattcgt aagtttcgcc
    12241 gttatacttc attcgatttt ttaatgtatc agctttcgct gcatatttta cctggtgttt
    12301 tgttttgtca taggtcactt caccagatac atcgaatttt ttatttgtac cactttcaac
    12361 gtgtgcatcg acgtaattta cttcttttgg taaattatcg attaactcaa atcgatcgta
    12421 aaccgctagt aaatccactc ctaatcgatt caccttctgt ttgattcgat attgaatcgt
    12481 gtctcctact tgcaacattt tatcgttcac gttatttcca tttttatcaa cccctgtttt
    12541 ttcaggttga tcaggaacaa cactaaagat tgtcgcagaa gataaagtaa accaggtttg
    12601 aacattagaa gaaccaatca caaacgtcgg atttgcttca gatattttaa aggacacagt
    12661 accttgacca aacttcggat ctcctaattt atcatgcaaa ttattgaaat cattatccgc
    12721 ttgtgtcagc ttagagcttc ctcctgggtg gccacctacc acgttcagat tgttgtagaa
    12781 agatttaaat tctgaaagaa ccgtatcttt tctgacatac caatctgtcg tattcatttt
    12841 gtcatagtgg gcatattctc ctttaagatc cgtggttttt cctcctgcag ggttcaaaga
    12901 gttaaaactg ataaatgtat ctcctgaaaa ttgaacgggg ctaccgtcct catatgtggc
    12961 tactagctgc acattcattt gtgttgaatg gtaaacaatt cctgagaaaa gattgtctga
    13021 gatccaaagt actgttcttt ttttagattt actcattgca ccattcgtat ttttatagcc
    13081 atcgtctcga aaatgagttt ttgtatagtt gttatctagt agattccacg gcaacgtatc
    13141 cgagtataag tgaatattag atagaactag cttgatattg acttttttcc cgttatacgt
    13201 accgattttt ccatagtcaa tattgacttt ggtgttggtt gttacgcctt ctaaaacaag
    13261 gtttgtttca ccgtattctt tttggaaaga aggatagcgt atatttttgt ttccctccac
    13321 taatcctacg tagtcgtctg taaaaccacc tttgttggca tcaacatgat atttgtaaac
    13381 ttttgacgct ccgtttacag taatatttgt ttttgcatta ggaacatctt ttggaataat
    13441 aaaattattc tttacgttct ggattggatt tgacggatcg acaataactt tttcagcaaa
    13501 gacattggct gtttttaacc caaacaatgt acctaacatc atcattatgg gaaaaacata
    13561 ttttaaccgt cttgtccacg agtgtttaaa attcatccct tcatcccctc ttttttataa
    13621 atgactagtg aaattccgac aataacgatc aaattgatcg tagtaaataa tggattccta
    13681 atgagctttt ccataatatc tagcggcatg gaagcagctg gtatgtttaa aatcctcatt
    13741 aggtatagtt ggtagcttgg caaaatagat agtttagaaa ataataaacc gcagtacaaa
    13801 aagactgcgg ttaaacaaga aaaattgaat aataataatt tgatcagttt cattttattt
    13861 cttccttaat ctctagaaaa caagtgagta acaaaatccc aacaattctc aaagaagttt
    13921 ttctttacgc cagtagaaac gatttttttt acttcttctt taggttgcga agcttctgat
    13981 ttaggataga tccacacatc ctttaagaat tcaccgtttt tatcagaaac aggtgttaat
    14041 agcaaaatat cctcgctatt agaaatgttt tcaggacttg attcattgac aatataataa
    14101 gcttgtttct gatttgcctg tacttctatc gagaattcaa agacacctgt ttgttgatca
    14161 attgtctttg tttttccatt agaaactagc ttcaattgat cactgaatag ttttttcact
    14221 cgatctttta attgggattc aatttggtca gtagtgagat ccttaacatc catcttttgt
    14281 aaaatgtccg atacatcata aacagaaaac ttcgcgccat ttactccttc ttgtttttca
    14341 agtttttgcc cctggttgtc taattgttcg gaagaaataa ttttttgaac gtgaatggtc
    14401 tgtttgacta tttgatcgtc ttcagcaatt ttcggttctt ctgaagaatc aactgttgac
    14461 gaatcgacgg tttcatcgct gctttgaatc gtgctgctat ctgacgtttg gattgtttgt
    14521 tctgtgctat ccgtgctttc ttgtctgtct gcaaacgtca actgtgtgta ggcagtgaaa
    14581 gaaaaaagag cggctgcaca aacaaatagc cattttctat ttctcatgtt ggttaccctc
    14641 ctttattttt tctttttata aacaaatagc gaaccaatga tcatgactga aagaaaaaca
    14701 gtacttccta aaagccatgt ccaagataat ttttgtttct tattttcttc atcttttaat
    14761 tctgattttg taaaggttac tcgcttccca tacactagaa aacggtgtgt gttgatcccc
    14821 ttaggcgtac atgtcattag cgttactcga tcttcattgg gatttggttc taagtaagtg
    14881 acaaagtttc tttgtagttc gtctttttgc acttcctcaa tccgatcgat ttgataagcg
    14941 tgctgctcac catcaacttt gatataaaac ttttctccct tttttactga aggtaaatca
    15001 tcaaaaagat tatctttata aagtccacta tgacctgcga ttaaaggatt tttaccgttt
    15061 cctcctgtaa tatcaccagt tccttccgta atacctacac cattttctaa aattttgtcg
    15121 gacgttccgt cataaattgg tagttttaaa gaaatacttg gaattgtaag aataccaaca
    15181 ggatcgccta actcaatctt agcaacatcc aaagaagaat ccgtttctgc tgccgttcct
    15241 gttcgatcga ttgcgacaat ctgctgattt tgttggtatt tcgccacgct cgcttcagca
    15301 ggcatcaaaa gtaagacacc tacagctgaa agtaaccaga aagcaatgat ccatttaccc
    15361 atgattcgct ttttcttagg cttcctgata atcattggtt ttgatccttc taggctttct
    15421 tcttaaagta aacaactgca gaaagtgccc ctgctcctag caacaagcaa gagattaata
    15481 catacgtttg aaaaccgttg ctaccggtca ttggtacgga agctttttga ttgtttttga
    15541 tcgtgattcg gttttcttct ttgtatgaat ctttgtctac tttgaaagag atctctttcg
    15601 ttaatttttg atagttttca ggcgcttttg tttcttccag tgaatattca ccttcagtta
    15661 aaccagtgat ttcaaagtga ccttctttat ctgattttag gatcgctgca tttgctacat
    15721 cgtctaccca tactgcttct ttgacaccgt ttttatccgt atcaactaat ccaccataat
    15781 attttccttc tgcgttttta gcagcaaatt ctgcgccttc aagcggtgtt gctttgattc
    15841 ctattccaaa tagtccgcta tcgactttta agaattttgc accataagtc acaacgtcag
    15901 ctttcgtttt ttcgtggtgt tcttcctgat taaatggatt gttgttataa acgaaatcca
    15961 cgctatttgt taatggattg gcaacagctg cgctatcatt tacatacatg ttataagtca
    16021 tttgaagatc ttgtccgtgt aaacttgcta cagtatcact tacttggcca ttattcacga
    16081 taaaatcgat cacaaagcca ttttctgaat tttggatttt ataatctgta ttttctttta
    16141 ataccacaga tccatcttta tttgttactt tgatatttgc tttagcagcg acataagaaa
    16201 gtccttgtcc tgctatatcc ccccatttaa atacactgta aggagaagtt tcgcttttca
    16261 ctccgtttac tgtgataccg cctgctccgc ctgcaatgtc tgttgggata tgaatcgttc
    16321 cttgataatt tactgcgtca ccaatttgga aagaatgttc ttgtcctgtt ccatttgtta
    16381 ctgttttatc gatcactggt gctttatagt ttacgtatga agcttttaag tcacttgtca
    16441 cgccatcatt cgtaatttca aaggttaatt tattgtgcgc atcgttgcga gcgtctgcgc
    16501 ctaataaata ttgatctgct gttggttctt tatctgatcc cactacaact tctgaaggaa
    16561 cttccacaaa atagtatttt cctaacgtca aatcagtagc agtcagcttt ccttgatcat
    16621 ccgatacaag atctcctaat tttgttcctt ttccaggttc gcccttgtat aactcaaatt
    16681 ttgccccttt taaaggtgtt tgtttgcttt gagctgtgcc atcgtcacca aatttcgtta
    16741 attcaaaact caacttagaa acaatatttt taggatataa gtgaatgtct tttaaaaaac
    16801 ctgaacctgt attatcagtc attggcgcaa tcacaaccat tggttttgct ttttgtgtga
    16861 ctaatccagc agcggattta ctttcataaa ccacatatac attccctttg gaattgacat
    16921 aggctggttg atcagcaaaa gtaatctcac cattttcatc tacagctgaa gtaattttat
    16981 tggttgcatt cttgacgtac tcactgttag atcccttgtc ttctacatct ttaacgattt
    17041 cgtccacttt cgcgttggtt agatcagaat cttcagtcgg taatacttga tccgtaatat
    17101 ttcctaacgt aaactcaaca tcaccataat ctgccttgtt gtatttcgtt acacctgtag
    17161 gatattgatc gtgcgtataa ccatcgtttt tgatcccgtc aatatcaaca ttcaattgcg
    17221 ttccttgatc gtacattaat ttatgaaccg tgatattgac cttctctggt ggcgtttttt
    17281 gtgtgacatc ttctgcatat gcttgatacc cctgaaagca gcttgcaatg attcctaaca
    17341 ttccaacaag cattccagct ttttttacat accgatttat tgccattttt ttatctcctc
    17401 atttcatatt tcaacgactc gcgttgatta aaaccttgtt attgtagctc tccctgtacc
    17461 acgtatcttt cttttccttg tgacgtataa acacaagtaa acaacgttaa taagggtttc
    17521 tctcctttct ttggcaaaga caagaaagag ttctcttcag gaacgccatc gattaattta
    17581 aagtactcag gtacgataaa tttacgcgtt accttgtaac gatagacgcc atcgttacta
    17641 actaagtcca tcacctcccc taatgacaac ttttgaatat cagaaaataa aacacctggc
    17701 atttccatgt tatgacctgc taggacatag tttcctttgc ccatttcgcc atcttcataa
    17761 aaataagtag ccgctccaag actcaaagtg tattgatttg tccctttaaa aattggcaat
    17821 gctaaaccaa gtgcaggaat ctgaatttgt gcaaatactt gtttattgac gcccatttcg
    17881 attgcttctt tttgtatgga caacatttga cccaaagaca tatcattatt gacgttcgtt
    17941 gcatcctcct tataactctt tgcgtgtgca ttgatttgat ctacgggtat ctttttttct
    18001 atattttgct taaacacctc tccttcatgt ttttggtagc taacatagcc aaacacactg
    18061 caaaagacga ttaaagcgac tcctaaaaaa aaaataacca ttttttcatc catctgcctc
    18121 ctttcagata aaacaaaaaa cactttttca caacgaaaaa gtgttttctc ttattactat
    18181 tctatttcat ttatctggtg gttttatatt ggtgtgtagc cattgctaac attaagaata
    18241 caattggcac ccaactgatt gtagttaatg tttcttccat gaatgattga cacatgatcg
    18301 ctaaaaaagc ccacaagaat gttagttgtc cgtttgtcag ctcacatttt cttacgagca
    18361 accataaaaa actaagcaaa ggaataatcg atagagcaaa accaatcaat ccatagtgat
    18421 tgacgagtgc gtgatacgta ttatggttac ctagaatctg atttcctata tggaaaaaga
    18481 aaggtttcat ccctacaaat atttgtcctg ttttttcgcc taatgtttca tagaatttgc
    18541 gccaaatttc ttctcgtcct gtaaataaat gaactttgtc tgacattgca gcaaaataag
    18601 aaatcggtaa agctagaacc gaaactgctg catacatcca aaaggacaag tgtgtgtttc
    18661 gaaaaatctt cttaggtaaa atttctagga taacgaagat aacaagcgcg tataatgctg
    18721 ctttcgattg gcaaacccaa atcgttgccc cagcaagaat caacgctggt aatgatagca
    18781 atcgcatgta ccattttaca aatgaactag caaatcctgt gataagaagg gctaatgtca
    18841 ttaaagaact acctatcgta tttgtattga tccaaatatc tgataatttg ttcgatggat
    18901 tccaaatact ttgtccttct ggtactggta tctcggtaaa tactcgataa accgttacga
    18961 gtaaaaagac atagaatact acaagataca agctacgatc aaacacagta aattccgtcc
    19021 attttacaat caaaataatg gcaataattg tcggaacgat cagatcacca tagaaagtat
    19081 ctactcggta gcttctaaaa aaagaaaaga aaaggtaaaa aagaatgcct gctgcaatga
    19141 agaataaatc gtttctcttt accttgtaca gattcaaaag aaacaaacag cctacgaaaa
    19201 acgtcactaa ctgtgcagca ttatcataaa taatatcgta ggaggattta accccaccgt
    19261 ccatattaaa tatagaatgg ataccaacag taacagaaaa atggcactca ttttattgat
    19321 caatttttct acaagttctt gaatgtgact cacttccctt atttattgat tttttctaca
    19381 ttgactaatt cgcactggat cacatcgcac tttttcatat tatttgcttc aaagtctaac
    19441 agtgtgagta gtggtttttt acctgctttt ggcaaggata aaaaggaatt gttttcctta
    19501 gattgaacta cctggctgta atcataaatt tttcctcttt tggagacttc atactgatac
    19561 ttgtaatgag catcgattag atcaatttct tctccttcag ataaatcaat catatcggat
    19621 aataaaacgc ttggtgtatc tacgttataa ccagcaagaa tataatttcc atttcccatt
    19681 tcagcatctg gataataagt agaagctact cctaaactaa gcgtatcgct attcgctcct
    19741 tgaaaaacag ggagaataaa tcctgtagaa gaaaaaacaa gttttccagc aatttcacct
    19801 ttgagatcct tttctaatgc ctgtttttga ttagtaataa gttgtctctt agaaatatcc
    19861 gttaaactgg ttaaattatc ttgataggtt ttatcctgtt cctgaatatg gattgttttt
    19921 gttacaccat ctactttttc agcgattttg tccttttgat gaccttgata agcaaaataa
    19981 ctaaaaagga gaaaaacaat gattacgccc acgtaaggat taaataaagt tttattgttt
    20041 ttattcatct atctaccttc tatatttgaa ttaatttacc tacatctaac caagataaac
    20101 cgcgttaaat tttactattc tttttattaa ataacaatgc cacatcataa ttgatcattt
    20161 tcatatcata atcgtcaaga aacttctaat aatagttggc aattagatct tattttcaca
    20221 taagttcgtc tcaactgttc aaaatttttc attgatccca atagacaggc tttctccttt
    20281 cctgttatct gcatgtcact gatatattgc atgacagata accttttaag gtgtttttgt
    20341 ttcatcgttt ttagtaactt ttcttccatt tctttcgaca cttttttcta ttttcgattt
    20401 ctttacaatt catgagtttt cctaccttcc ttgttttgat aaaaataaaa aagcctatga
    20461 tcacatacgc tctacacttc actcttgggt tatctttttc tttcttttaa ctactggcct
    20521 tgctggtttc aaatccttga ttccattata gattctccaa taatcaaact cttttcgtaa
    20581 tctttctttt tccatatctg ttcctttgga taaggcttta aatacatctt taggtgaata
    20641 actacgagct aacagctgta cataccttcc ttttgtcaaa gtatccatat ccatcgcatc
    20701 taaaactggt cgcgccatct aatttgcctc ctaaataaat tctttactcg atgtctaatg
    20761 ataatactag ctttttatta ttcgtcgtaa tttctgcaca ttcttcttca ttattttctg
    20821 cgattaacgc ataatagcat ggtgatttta cttcgaaaaa tttcatgatc tattcctcca
    20881 atttttattc ttctttatcc gctacaaagt caatgatttc aacactgaca atataatcac
    20941 tcaaatatga ccaggtatct tctacagaca attcgtctcc tttgtcgttc gtaagcgtca
    21001 ttttaaacca ctcatcgcct tcatcatctt caggtagcaa gccgaatcca attggattat
    21061 cagtcaatgt ttaatcgtat aaatcatcct cgtctaatgc taaaacatct aatcctttac
    21121 aatttccgcc tcttctaaac gtcacaaatc ctttgtaatc ccaacgttgg aaagaaacct
    21181 taatagtatg tgtgcccaat cgtatattcg gatcataatt tttcatttgt cattcctcca
    21241 ttacgtaaat ttcattttct ctatgtttta tatcaatttt ttcactttat tcaggacttg
    21301 ttcatatttt atcgtttttc gtttacttaa aaatacataa aaaatttcga ctcgtttatg
    21361 gcgtccgaaa cgagaaaccc tagtagacag cggtaaatgc tcgattgatc caataatcaa
    21421 cgtcctcgca agtatctaca tgtactgcag cacacgacac aatttcttgt gcgtcctccc
    21481 cattacgaga agacctactc cttattccat gagtttgcat taaagtctag atcccttagt
    21541 agctgctcat gattaatcta gacgctattc taacttgtct aacttctaaa ttccctcttg
    21601 tttactctgc gcttattatt tacacaaatt catttcacca ctatccaaac aagcgcattt
    21661 actcgattga ccaatttttt acgttaccaa tcgttaaaac ctaccccgtc actccccgaa
    21721 gggaattgtt gatagatcaa gtctactcct tatttttcta gtgactctaa gttcctttag
    21781 aagtctcgac aatattttca agcaagcgaa aaacgataaa atacaagtta tgagaatgat
    21841 caattcagct gatcaaacgc cccatccctt ttgcggtaca acgcaagact ccattttttc
    21901 ttcgaccaat cagtacaccg ttttggtcat aaacatgttt gattgttgga tatagctctt
    21961 ttaaggggat aggatctttt aaaattattt gcttttgttt cccaatgtaa taaatcattt
    22021 cctctgagac tttgtctttc tggattatat atttcttaca ctgcacaacg gttttacttt
    22081 ggccagttga tagtttcttc gtgattttct ctgtagcggt acaccgttta ccgtagtgac
    22141 aaatatcttt gagactcaaa attcctgtat atgacataaa ataaaccacc caatttcttt
    22201 aaatattttt aacaagtttt tcttgttatt tttcaaaaat agagaattga ttttcgttca
    22261 tgacaaacaa aaaagaggga acgcatccaa acatgcgttc cctctaattt cagcgttcgt
    22321 catacggcaa agagccacac ggacattttt ataacattat gcttaggcat agattcatcg
    22381 taatatcacg tatttttaac cttaacacag ccaaaaaaag tggtatcact tttgaatatc
    22441 tgttatacta aatccgttgc gggtaatacc gtaacactga aaggttaacg cattaagggc
    22501 caaatcttaa tgccgtgtat gaacgctgac gaagattacc agccttccga gttcataccg
    22561 cctttctttt ttttgtattt tcaattgtcc aaatttatcg tccaaaagtg cagaacgaaa
    22621 atcaattcat cacaggcata gcagacaatt aaatttatac aaaaaaatgt aagcgaataa
    22681 tattcgtatt gcctgaaaag aagtaatatc aagattttta gcttgtttaa ataatgaaat
    22741 tatctctctt cgcgtattat tataactcaa aaaaaaggag tatgcaaaca tacgttccct
    22801 tttctatatt tgaaattaat tatttctttt aacacttatg acgtaaaagg ctacgtttgt
    22861 gatttttatc ataatatttt aacttataaa ttctattaaa atagctatta ttttgtaata
    22921 ttcgtaatat aattagaata ataaaaaatt tttaatttta atgttactcc atgaagcaac
    22981 aatcactttg tcagtaaagt ttcactctaa ccagtctttc gtaatagtgc ttggggagct
    23041 ttcataattc aaacgttttt cacttgatac tttagcagct attggttttt cgataaacca
    23101 attttttaca tagacaaaaa tcaggttctg gatattttcg actttttcgg tttttaattt
    23161 ttgataggct tttaacagtg tcgtgtataa ttcttgttct gcattgacat aataactatc
    23221 gagttcttca aaaactatcg aaataccact ttctatttca gcttttttct ttgcattatg
    23281 aatagtctgg acggtttttt gagcttcact gtaacttgaa gaaaatgttt ttatcaaatt
    23341 taatactcgt tcagggacaa acgtagcaat gctgtcgttt gtcataattg tctcaaaatt
    23401 gtctaacaac aattgatctt gtaggcggtc tttttcagtg tctatattgt gtctattagt
    23461 gtctaatata ttattattaa gttctggtat gattttcata ccctctgatt tatcaacgtt
    23521 ttggcacggt atgattttca taccctcttg agccccaagg gattcagcgt ctgatttttc
    23581 gtcgagggtg ggtatgattt tcataccctc tgatttatca acgttttccc tattctctct
    23641 atcaaatttt tcgagtaagt agatatcatt ttctgagact tttaattctg ctagatatag
    23701 tctattagga ttatttttcc ctaactgttt gttaaatccc atctgctttt gtaataataa
    23761 accaaaggat tccaactctt ttttgattgc tatcgctttt tgtttttggc agtttaatac
    23821 gctacatagt tcatttgtcg tataagtaaa ataaacatta ccttcttcat cgatttgccg
    23881 tttgctgatt gcgatctcta atcttgcttt taaaagcata taggcaatct tagttgaatc
    23941 tttcattttt ttgtattcgt cagaaacaat aaagactttt ggaaattgat aaaataattc
    24001 gttataaact ctatccgcct taaaaaaatt aaaatcagtc attgtagatc ctctactttc
    24061 acgttgtttt atttatgtaa aattacctac tcttttcgaa aatagcaaag ataaataaaa
    24121 aatgcaaacg cattaaaact gttttttaat taaatactac ctaaaatcag aaataaaatg
    24181 aattatgt
//
LOCUS       DADVXM010000036        23828 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.037, whole genome shotgun sequence.
ACCESSION   DADVXM010000036 DADVXM010000000
VERSION     DADVXM010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.037"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(53..787)
                     /locus_tag="KB927_001512"
     CDS             complement(53..787)
                     /locus_tag="KB927_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBB6840433.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="KB927_001513"
     CDS             1114..1524
                     /locus_tag="KB927_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBB6840434.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="KB927_001514"
     CDS             1517..2218
                     /locus_tag="KB927_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBB6840435.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="KB927_001515"
     CDS             2218..3804
                     /locus_tag="KB927_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6840436.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="KB927_001516"
     CDS             3823..4044
                     /locus_tag="KB927_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBB6840437.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="KB927_001517"
     CDS             4041..4802
                     /locus_tag="KB927_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBB6840438.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="KB927_001518"
     CDS             5182..5691
                     /locus_tag="KB927_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBB6840439.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="KB927_001519"
     CDS             complement(5766..6305)
                     /locus_tag="KB927_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBB6840440.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="KB927_001520"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="KB927_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBB6840441.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="KB927_001521"
     CDS             7318..8169
                     /locus_tag="KB927_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBB6840442.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="KB927_001522"
     CDS             8197..8832
                     /locus_tag="KB927_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBB6840443.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="KB927_001523"
     CDS             8852..9625
                     /locus_tag="KB927_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6840444.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="KB927_001524"
     CDS             10033..10830
                     /locus_tag="KB927_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBB6840445.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="KB927_001525"
     CDS             10808..11221
                     /locus_tag="KB927_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6840446.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="KB927_001526"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="KB927_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBB6840447.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="KB927_001527"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="KB927_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBB6840448.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="KB927_001528"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="KB927_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBB6840449.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="KB927_001529"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="KB927_001529"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBB6840450.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="KB927_001530"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="KB927_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBB6840451.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="KB927_001531"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="KB927_001531"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBB6840452.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="KB927_001532"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="KB927_001532"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBB6840453.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="KB927_001533"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="KB927_001533"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBB6840454.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="KB927_001534"
     CDS             21905..22483
                     /locus_tag="KB927_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6840455.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="KB927_001535"
     CDS             22535..23017
                     /locus_tag="KB927_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBB6840456.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="KB927_001536"
     CDS             23134..23508
                     /locus_tag="KB927_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840457.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4285 c         5115 g         6647 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaga
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcacccggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaataa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagttt
//
LOCUS       DADVXM010000037        23573 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.038, whole genome shotgun sequence.
ACCESSION   DADVXM010000037 DADVXM010000000
VERSION     DADVXM010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.038"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(461..1090)
                     /gene="udk"
                     /locus_tag="KB927_001537"
     CDS             complement(461..1090)
                     /gene="udk"
                     /locus_tag="KB927_001537"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBB6840458.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1174..1869)
                     /locus_tag="KB927_001538"
     CDS             complement(1174..1869)
                     /locus_tag="KB927_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBB6840459.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1882..2598)
                     /locus_tag="KB927_001539"
     CDS             complement(1882..2598)
                     /locus_tag="KB927_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBB6840460.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2928..3533
                     /locus_tag="KB927_001540"
     CDS             2928..3533
                     /locus_tag="KB927_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBB6840461.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3858..4181
                     /locus_tag="KB927_001541"
     CDS             3858..4181
                     /locus_tag="KB927_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBB6840462.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4363..5733
                     /locus_tag="KB927_001542"
     CDS             4363..5733
                     /locus_tag="KB927_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBB6840463.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5863..7164)
                     /locus_tag="KB927_001543"
     CDS             complement(5863..7164)
                     /locus_tag="KB927_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBB6840464.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7394..9352)
                     /locus_tag="KB927_001544"
     CDS             complement(7394..9352)
                     /locus_tag="KB927_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBB6840465.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9529..9795)
                     /locus_tag="KB927_001545"
     CDS             complement(9529..9795)
                     /locus_tag="KB927_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6840466.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10305..12431)
                     /gene="pnp"
                     /locus_tag="KB927_001546"
     CDS             complement(10305..12431)
                     /gene="pnp"
                     /locus_tag="KB927_001546"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBB6840467.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12619..12888)
                     /gene="rpsO"
                     /locus_tag="KB927_001547"
     CDS             complement(12619..12888)
                     /gene="rpsO"
                     /locus_tag="KB927_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBB6840468.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13139..13702
                     /locus_tag="KB927_001548"
     CDS             13139..13702
                     /locus_tag="KB927_001548"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBB6840469.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13955..14476)
                     /locus_tag="KB927_001549"
     CDS             complement(13955..14476)
                     /locus_tag="KB927_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBB6840470.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14479..15321)
                     /locus_tag="KB927_001550"
     CDS             complement(14479..15321)
                     /locus_tag="KB927_001550"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBB6840471.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15314..16039)
                     /locus_tag="KB927_001551"
     CDS             complement(15314..16039)
                     /locus_tag="KB927_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBB6840472.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16215..16511
                     /locus_tag="KB927_001552"
     CDS             16215..16511
                     /locus_tag="KB927_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840473.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17079..18671
                     /locus_tag="KB927_001553"
     CDS             17079..18671
                     /locus_tag="KB927_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6840474.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18684..19424
                     /locus_tag="KB927_001554"
     CDS             18684..19424
                     /locus_tag="KB927_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6840475.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19592..20941
                     /locus_tag="KB927_001555"
     CDS             19592..20941
                     /locus_tag="KB927_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6840476.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21069..21659)
                     /locus_tag="KB927_001556"
     CDS             complement(21069..21659)
                     /locus_tag="KB927_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBB6840477.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21806..23158
                     /gene="brnQ"
                     /locus_tag="KB927_001557"
     CDS             21806..23158
                     /gene="brnQ"
                     /locus_tag="KB927_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBB6840478.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6751 a         4746 c         4490 g         7586 t
ORIGIN      
        1 tagggggtgc gacaaaagag cttcttcaaa aaaataagtc gaaatctcac acaaattcga
       61 gaaataattt tcgtaagttt cttcttattt attgcatctg accacttctg ttacaacctc
      121 tcgttaaacg gtgttcaaaa gcttgcatct acgataataa gcccaaccca acgaaaaacg
      181 tgaggagctg ttttatttgg atgctcttat cgcttgatgc aaagacagct tttttacaac
      241 ctctacttca cggtgctcaa tcagctgacc ttcggtatta gctcaaaaaa cggtaaaata
      301 taaacagcta ttttccgttt cttcttttta atacttaggt caagatgctg ttttcacaac
      361 ctcttgttat aaataaaaaa acagttggct ggtgactgtt caaaaagcag aatccttgct
      421 tttcaaacgg tcgcagtccg ttcaactgtt tcgctgcgca ctatttatgg tttaagaaac
      481 tagctacttt tgttgtaatc aaatcaatag caacgtggtt ttctccgcct tctggaacaa
      541 tgatatccgc atagcgcttc gttggttcga taaattgatg atacatcggt ttaacaactg
      601 tcaaatattg ttcgatcacg gagtccaatg tgcgtccccg ttcttccata tcccgtttga
      661 tacgacgaat gatacgaatg tcatcatctg tatctacgta tactttgata tccatcaagt
      721 cacgcagacg ttcgtcttct aaaatcagga ttccttctag aatgatcact tcttttggtt
      781 cctgaatgat cgttgcctga cttcttgtat gcgctacata gtcatacacg ggtttttcaa
      841 tggctttata gttcagtaag tcgcctacat gctgaatcag cagatcatta tcaaaggcaa
      901 atgggtgatc gtaatttgtg ttcaatcgtt cttcaaaact caaatggctc tgatccttgt
      961 aataagaatc ttgttcaagc atcatgatgg aatggtccgg gaagttgttg aaaatcgcac
     1021 ggctgacact tgtctttccg cttccggatc cacccgtcac accaatgata attggcttgc
     1081 tttttgtcat tgactaaaac ctctttcgta tccgtttttt cattctaatc tattatagcg
     1141 aaaaaacacg aaaatgctat atttttctga aaattaatcc ttttcaattt ccaataatga
     1201 ataaagttcc tctaatgaat cgattcgata agtaggctgg atttcttcga tttctggtaa
     1261 tttatttcta ttgaaccaaa tcgtatcgat ccctgccata tttcctcctt tgatatcaga
     1321 agtcaaagaa tcaccaatga tcacagtttg ctttttatca aaattaggaa tgtgggaaaa
     1381 gacatgatca aaaaattctt tcatcggctt ttgcgctccg acagcttctg agacaaagat
     1441 atccttgaag taatcaagca ttcctgcatc tgttaatcgc cgatgttgcg tgtgcgacac
     1501 accgttcgtc acaatataaa gatcagcatg cggatggacc tttttcagga tttctagact
     1561 tcctggaaca agatcatgac cttggttcaa gtagtggcgg tagcgttttt ccatttgatc
     1621 actatctact gttttcccaa attgctggaa aagtaaccca aaacgactgc ctattatttc
     1681 ttctcgtgat agtctgcctt tttcaaactc ctgccataaa tgatgattca aagccttata
     1741 gctggtttcg atttctggtg tcaatgtgat tccttgttct gcaaacaaag cacttaaagc
     1801 attggcttca gttaattgaa aatctaacaa tgtatcatct acatcgaaca ataaagtttt
     1861 atatttcatc tttttgacct cctatttaaa ataaatactt aactttttca tctctgctaa
     1921 tgtcaacgat cgatactcgc ctactcctag ctgttcatct aattccaatg gtcccatgct
     1981 tagccgtttc aatgcggtca ctttctttcc ttgggctaag aacatctttt tgacttgatg
     2041 gaattttcct tcttggatcg tcaataaaac cgtactttgg tgcttgtctg ctttgagtat
     2101 ttttaaatca gccggcttac attgataccc atcagcgaat acgattccat tttcaaatgc
     2161 tgttacgtct gccggtgtca ccctttcgtt cacaactact tgataagtct ttgaaacctt
     2221 tttttctgga agtagcattt catatcccaa ttgtccattc gaagtgatca gcaatagtcc
     2281 tgttgtatct ctatctagtc ttcccactgg atataatggt tggaaacgat cggcacttgc
     2341 aatcagatcg attactgtcg tcttttctgg atctgataca gctgtaacag ctttttcagg
     2401 tttattgaga agataatagg actcatttgt ttctaagtgt tcacctgcta cttcgatttg
     2461 atgcagtaaa ctatctacat ttcgattttg tcgaaattcg actgtgccat ctatcatcac
     2521 ttgcttcaaa gcaaacagcc gcttcatttc cttgcgtgtc gtttctaatt tttcttctat
     2581 taatttatct aaacgcatgc tgtttccttt cttattacta ctaattaatt ataccttgaa
     2641 tattcttgct tgcaaataca tcatcatagt tattccttga cttaattaac agttcacgtt
     2701 acggttaaat agtaaagtga attggatttc tcatacacag cgtaatgacc tggtggagaa
     2761 aagttgaatc ctgactttct aaggggagat gcgcgcatct ctccttttgc gcttttttaa
     2821 gcgccctgcc ttcgatgatg tgcacgagat tagcctttag aattcactta aataaaatct
     2881 gtccgttacc aaagcagaca gtcacatttt aaggaggaat tttggttatg tcagtatcat
     2941 tagaagtaag taaaagagaa gtacgtcccc gttcattaag aaacaaactt cgtcacgaag
     3001 ggaaagttcc agctgttgtt tatgggtata aagtagaaag tacccctatc tcattcgatg
     3061 gtttgacact aagcaaattg ttgcgtgaac atggagcgaa cacagtcatc acgatggaca
     3121 tcgatggaca aaaagtcaat acattggttc acaagatcca aacgaacact tttaccaatc
     3181 atttcgaaca tgcagaattt ctatctgtaa acatgtcgga agaaacagaa gtcgaaacag
     3241 aagtcgttct tgttggcgaa tcagtgggtg ctaaatctgg tggagtgtta gctcaaaact
     3301 tgtatacagt agtcgtatct gctacaccag acaaattgcc tgaacgaatt gaagttgacg
     3361 tgacaaactt ggaattaggt gattctatta cagtagccga tcttccaaaa aacgacgatt
     3421 acaaattcgt gaccgacagt gaagagcaaa tcgctgctgt agtcgctcaa agtgaagaag
     3481 aaagcacagg tgaaggtggc gaaccagaag tgatcggttc aacagaagaa taatactgaa
     3541 acaatcaggt ggtgttagaa gcggcgggtc agcagctttt aacacgcctt ttttatttct
     3601 aatcgtttat tttcatatgg ggcttccact tttgtaaatg gctttacaaa cgaaaaatcc
     3661 taatttacca agcttttcct cgcatacttt tatcgtacct ttataaaaat ttatactttg
     3721 aaaaaaagta ttcaattatt gttgcatttt tcctgattct ttattagaat gaaccctcgt
     3781 tgaagtaagt atttctagtt tatcctagga ttaattataa aaataaaaca ttcgttgatt
     3841 cgaaggaggt taaacagatg tttgaaagtt ttgatagcag ccgcaaccgt tacgcttcag
     3901 ttggtgtcgt atcaagtttg ccagatgaat tgattgacag tatatggttt attattgacc
     3961 tagatcttaa gggagtcatt ccattagaaa atatattaac ctttgatttg atcgaaaatc
     4021 gtggaaaagt gacgatgcat ttttctcaag caggaagcaa tgtggaaatg gatattgatt
     4081 tgccgtttgc ctattcgaac caatttcctg ctcaagtata cgcctatgat gacggtacga
     4141 gagaaacgat ccttttacca agtgagatta gacaatatta aggtgataga taaacgtgga
     4201 tgtcccttat tttacagacc aggccaagtt gttgattctt tgactcaatt cttggcttct
     4261 ttttatggag tttcataaat tatcattgat ttctaattgg tattctcagg ataaacgcta
     4321 tatactacta actaaatttt aaagatataa ggagtttaaa agatgcgcga tttaacaaaa
     4381 ggaagccccg ctaaactgat tttgatgttc actgttcctt tactgatcgg aaatgttttt
     4441 cagcagttct acaatatgat cgatatgatc atcgtgggtc agacgctagg taaaaatgcg
     4501 ctggcagcgg ttggtgcaac tggaagcctg acatttttga tcattggctt tgcccaaggt
     4561 ttaacagctg gtttagccat tattaccgca caacgttacg gtgcaaaaga ttatcggggt
     4621 ctgaagaaaa gttttgctgc tagtgttgtc attagtcttg tcgtcactgt gattttaact
     4681 gtcctaagtc tcctgtttat tcgtccgatg cttcaattga tgcaaactcc tcctgaaata
     4741 cttgatcaag cacaaacatt tatttcaatt attttattag ggatctttgc atcagtcagt
     4801 ttcaatttgc tttctaatgt cattcgcgca cttggtgaca gccgcacacc actattcttt
     4861 ctgatcattg cggtcatcat caacgtcgta cttgatttga tctttattat ctattttggc
     4921 atgggtgtgg aaggtgcagc tattgctaca gtaatcgcac aagtttcttc cagcgtactg
     4981 tgtctagtgt atatcaagaa aaaaatgcct ttgttacagt tacgcaaaaa agatttcaaa
     5041 tttgaaaaag aagagtttgc tgtacaccta aatgctgctt tgccaatggc gtttcaatct
     5101 tcgatcatcg ctgttggtgc tatcgtgtta caagcagcac taaatagtct agggacagat
     5161 gtcgtagctg ctcaagccgc tgctggtcgt atcgaccaat ttgcaaatca gccgatgatg
     5221 tcatttggta ttgcaatggc aactttcact gcacaaaact atggtgcgaa agaatatggc
     5281 cgaatcttgc aaggggtacg tcaaacttta ctgatgagtg tcggatttag tctcttagca
     5341 ggtgctatcg tcattttctt cggtcatttc tttgttcaat tgtttgttag cccatcagaa
     5401 acacgtgtat ttgaattagc acaaacctac ttcaatatca atgggtctct ttactggatc
     5461 ttagcagtcc tgttcatttt acgctacaca cttcaagggc ttggacaaag caagatccct
     5521 acgatcgccg gtatgatgga attgcttatg cgttcttttg cagctatcgt tcttacagga
     5581 atgtggggat acccaggagc agcagcagct tctcctttag cttggatcgg ttctgttgcc
     5641 gtgttgcttt actcttatat gcgttcgatg aaacaattga aacacatggg tgaagaggaa
     5701 catttcacat tagaacatgc agaagcaaga tagccttgat taaaagaaat cgttgcggct
     5761 aaaaatgaaa acttttattg aaaatatctt cttcgtttac cgaaaacagg ttttttagat
     5821 aacaaaaagg ctgtgacaaa aaatgtcaca gccttttttc ttttattcta tttttctttc
     5881 cgtggactct actttgaaat aatcgatatg tgcatgctgg tattctaata ccgtgaaacg
     5941 gaatgatgca atctcaatga ttgttcctgc ttttatttct ttatatcggc tagaagcaaa
     6001 gcccgcaagt gtagtaaaat tcgtttcttc aaactctgga atctctacat gaaaataacg
     6061 ctggaaatca tctaatgtta gtttgccgga gatgatataa gagccatctg actgttccgc
     6121 tatcaatgct tcgtccaaat ctgtctcatc tcggatttcc ccgacgattt cttctaaaat
     6181 atcttcaatc gtcactaagc cgcttgtccc tccgtattca tcttttaaga tagcaatatg
     6241 ctttcccttt tttcgcatga tcgtcaataa tttttttata gggatcgttt cagttgttac
     6301 gatcggctct tcaatcaact gttctactgt cagctggtca tctttataag attgcttgat
     6361 caaatctggc aaggtgacat aacctaaaac attgtctttt gattctaaga taaccggata
     6421 gcgagtatgt ccttgttcaa tcgaagcttt tatcgcttct ttgacggttt ctgaagcttc
     6481 gaatacttgc atggacgtac ggtctacttg tatatctttt gccaaggtat catcaaattc
     6541 aaacacgttt tccaaataat gatattcttc tttggtcaac tctccttttt cataagaatt
     6601 caatgcgact aatgtcagct cttcttgaga caatgtctct tctccttcag atacgagacg
     6661 cacacctaat agcttcccta gccctgcagc tgaatgattc aatacccaaa taaaaggaaa
     6721 cattacttta taaaaataat gaagtggttt aactacgaac aagacgacct tctccgtatt
     6781 gacgatacta tagctcttag gaagcagttc gccaataacc acatcgatat acgtaactaa
     6841 aataaatccc agcgccacag agattgtact gctaatagcc gaactaaaag gtagtttacc
     6901 gatcactggt tctagtaaag ccgcgacaga tccttcaccg acccacccga tgatcaaacc
     6961 ggttagcgta attcctaatt gactagctga taaatagtta tctaaatggt gtgtaacatg
     7021 aagagctagc ttggcgttct ttacattttc cttttctagt tgttccaatc ttgatcgtct
     7081 gattttcact aaagcaaatt cacttgctac aaaaaatgaa gtaattgcaa tcatcaaaaa
     7141 taaaataatg aaattgataa ccatattctc ccgcctttct ctttttctat tgtacccttt
     7201 ttctacaaaa agattgaaaa taatgcgtat tcatatttag gaataaaaaa ggagatgcgg
     7261 catttttcag ccacatctcc ttatcacttc aaaatcattg cgttacttgt tgctaaacag
     7321 ctttttcatg acctctgata aacggtgttc aagtagctga cattcgacat tagttcaggt
     7381 caaagcgcta ctttcacaac cgctctttca accatgtttt ccgagtattt ccaatgataa
     7441 gcggaacagt ttcatgtttt acttcgctgt actctagccc aaaccatgtt tctggcgagg
     7501 tagcgatttt tttgattgcc agttttgcct gcatgatttg acgttgccat tttcctagag
     7561 ttgtcacatt ggaaactact tcatcaatca ggacaaattg gaaatcgcca acttctcgcc
     7621 ctggtgtcag agagtatctt tgtggctgtt ttggcaaacg gccttgtttc atcaaatcat
     7681 ggatgacttg gcgaacatat acgttgattt cctgttggac cctgaaacct aagaacagat
     7741 tcacttggac aataaaatca gtgtccatca tatctacttg atattctttc gtatatggct
     7801 catccgtcac ttccacatga acaaaccaat agactcgtgc tcttttaggc cgtttatcta
     7861 aaatcgaata gatgaactgt cggccaactt tatcttcagc catatcagga accaagaaga
     7921 ccacatttgt ctgatagatt ggtaaagaag tatcatcacg taattctcta agctgcggga
     7981 tataatctct caaagacaca tcctcggttg acgattcgcg aataatgttc ccttgttccc
     8041 aaataaacat cacgactaag atgatcaaac caatcagaac ggctacaaaa ccgcctcgga
     8101 agaatttgac aacacttgag ataaagaaaa cgacttctat cgcaccgaag aaaaaggtaa
     8161 ctaaatatgc aagccaacga gaatgcccat tttggataag ataaaagtaa agcagtgctg
     8221 ttgtcatcaa catcgtcaca gtgatcgata gaccgtaagc agcttccata tgatgagacg
     8281 ttcggaatgt gacaaccact agagaacagg cgatccataa aatcagattg actgctggga
     8341 tatacatttg cccgatactg ttcccaggat acatgatctt taaccgaggc agcagtttca
     8401 acttgattgc ttctgaaact agcgtaaacg aacctgtaat caatgcttgc gaagcaatga
     8461 ctgcagcgac tgttgcaaaa gcaacgccga tcacgatcca actttgaggc atcatttgga
     8521 agaatggatt caggttcttg atttgctgtg cttcagggtt ttgataaaca ttcaacaacc
     8581 acgcagcctg cccaaaataa ttgataacca aacaaatttt gacgtaaggc cagctcagac
     8641 gaatatttcg tttgccgaca tgtccaagat cggaataaag cgcctctgca cctgtcgtag
     8701 ccaggaaaat atttccaaga atgaacaagc ctaatttgtt atctgcacta aaaagcagct
     8761 ggatagcata ataaggattc agtgcacgga taactgtcca gtcttgactg aagttcatta
     8821 atcccattac gcctaaaaaa gtaaaccaag cgaacatgat tggtccgaat gcttttccga
     8881 caatatctgt accaaagcgt tggaccatga ataaaacaaa aataataact aaagtgataa
     8941 tgacgatcac gttctggtta ttaccgaacc ggtcaaaaaa ctgcggaatt cctcgcaagc
     9001 cttcaatcgc agtcgttacc gtcacagcag gggtcaatac cccatctgct agtaaggcag
     9061 ctcctccgat cattgcagga atgatcaaat atttcccacc ttttcggaca agtgtgtaga
     9121 gtgagaaaat tccaccttca ccatggttat ctgcattcaa tgcaatcacg acatatttga
     9181 ttgttgtcag tagagtcaat gtccaaaaaa tcaatgagac tgatccgata acaaaatcag
     9241 gattgattcc tgacaatccg ccattatctt caacaatcga tttcataacg taaagcggac
     9301 ttgtcccgat gtctccgtag acgactccca tcgctacaag caggccagcc attgatatct
     9361 ttttggtatt gtgcgttgtt gccacgtttt tccctcattt cttgttatat ggatatcctt
     9421 taggtaagct tgaatgatag atgatattct tatccatgac acccgctttc ctaaattgct
     9481 tctaattatc caagtaacac actgaagtgt caacttattt gaataaaatt attctttctt
     9541 tggacgttct ctgatacgtc ttgccacaaa tgaataaaga gcaaggcaaa aaattgcacc
     9601 caataatgct ggtatcaaat aaaaaccgcc gagttccggt cccagtggtc ctagtaaaaa
     9661 ttcgccgagc caactaccta aaaaaccgat aatgatattt ccagatacgc ctcccgggac
     9721 ttcctttcct aaaattgcgc cagctatcaa acctaatata ccgccgataa ataacgacca
     9781 taaaaaattc agcatctcct ttccctcctt tatccatatt tctcactttt attttacgct
     9841 ttattcagaa ggactccaaa aatatgcgcc aagaaactcc agaaaaaaag aagttgtaac
     9901 aaaagtgttc agcttatttc cgtagaagct gcttctggaa caccgtgaat cagaggttgt
     9961 gaaatcagcg gtttgacctg agtattagag aaacaaacgg aaaaatagtt cctcatattt
    10021 tgccgttttt tgagctaata tcgagggaca gctgattgaa catcgtttat tggagaggtt
    10081 gtaaaaaagc tgttctgcat caagtaataa gaacagccaa gtaaaaacag ctcctaatgt
    10141 ttttaacttg gctggactta ttaccgcaga tgcaagcttt tgaacaccgt ttattcgaaa
    10201 aaaaaggact gtgacacggc ttttgtcaca gtcccctttt ttcgaataat tattgtcccc
    10261 ctgtcacctt cacgatcaca agtacattat tcctatgaat taaattattt ttcttcattt
    10321 ttcgttgaac catcttcgtt caacattgct tttcttgaca gatttacgcg tccttgttta
    10381 tcgatttcag ttactttcac aaggatctca tcacctagtt taacaacatc ttcgacttta
    10441 ttgacacgat cgtttgctaa ttgggaaata tggacaagtc catcttttcc tttgatcaag
    10501 ttgacgaatg caccgaattt ttcgatacgg acaactttcc ctagataaac ttcaccaact
    10561 ttgacttctt tggtcaaatc ttcgatgatc ttgatagctt ttttgatcat ttctgcatca
    10621 gctgaagcaa tacttacttt tccatcttga tcgatatcga ttttcacacc agtttcatcg
    10681 atgattccgt tgatcgtatc gccgccttta ccgataacat ctttgatttt agcaggttcg
    10741 atctggatca tttcgatttt tggtgcatat tggcttaatt cttcacgtgg agcagcaatc
    10801 gttgaagtca attcttctaa gatttccata cgtgcttgtt ttgcttgagt taatgcttca
    10861 gttaggattt gttctgtgat tccttgaatc ttgatatcca tctgtaaagc agtgatacca
    10921 tcttttgtac cggcaacttt aaagtccata tcgccaagat gatcttccag cccttggata
    10981 tcagttagga tcgtatagtt ttcaccatca gaaacaagtc ccatcgcaat accggcgact
    11041 ggcgctttga ttggtacacc tgcatccatc aatgctaatg tgccagcaca gatacttgct
    11101 tgggaagaag aaccatttga ttccaatact tctgctacta aacggatcgt ataaggaaat
    11161 tcttcttctg aagggattac ttgtgctaac gcacgttcac ctaatgcgcc atgtccgatt
    11221 tcccgacgcc ctggagagcc tgcacgtcct gtagaaccaa cagaaaattg agggaaattg
    11281 tagtggtgga tgaatcgttt gctgacttcc acccctaaac catcaatgat ttggtgctct
    11341 cctagaggtg cgagtgtaca agctgataaa gcttgtgttt gtcctcgtgt gaacaaacct
    11401 gatccatgta cacgtggcaa taagctgacc tctgatgaca atggacggat ttcatccaat
    11461 ttacgcccgt caggacggat cttatcgatg gtgatcaatt cacgtacgac atctttttca
    11521 agatcttctg tgatttgttt aacttctttc aacaagtgat cttcatcttc atgacctgca
    11581 aatttctcag cataagcttc gcggatatcg atcttcacct gctcgatatt atcttcgcga
    11641 gcaagttttt cttcagtcat tactgctgct ttcattgtag cgtaagaagc atcaaagatt
    11701 tcttttttca atacttcatc aacttgcagt aaagtcactt ccattttttc tttccctact
    11761 gcttgaacga tttcttcttg gaaagcaact aactctttga tagcgtcaaa accaaacagc
    11821 aatgcaccaa gcatgtcttc ttctgaaact tctttcgcgc cgctttcaac catattgatg
    11881 gcttgtttcg ttccggcaac agtcaattcg atatctgttt gttctgcttg ttctactgtt
    11941 ggattcaaga cgtactcgcc atttacacga ccaacttcta cgcctgcgat tgggccgtca
    12001 aatgggatat ctgagattga tagtgctaaa gaagaaccta gcattgctgc catagctggc
    12061 gagcagtctg tttctacact catcacgatg ttcgttactt ggacttcatt acggaagcct
    12121 tctgcaaaca tcgggcgaat tggacggtcg atcaaacggg cagtcaatgt tgcttccgta
    12181 cttggacggc cttctcgttt gatgaaacct ccagggattt tccctgctgc atacattttt
    12241 tcttcataat tgatcgttaa tgggaaaaag tctgtatctt ttgcttcttt agaggccaca
    12301 gctgcactta agactactgt atctccataa cggactaaaa cggctccgtt tgcttgtttt
    12361 gctagctgac cgacttcgat ttgtaaggga cggccgcccc atgtcgtttt gaatacttgt
    12421 ttttctgaca taacttctcc ttttccttct cgtgaaagca agacgctact aaacaaatga
    12481 aaactgccga aagccgtctt ttgagcagct ttcatttggt tagtaggagt ccatctagct
    12541 tgatcacgga attttactta attgatatac gagtaaaaaa agtgagattc atgtgaatcc
    12601 cactcttttt gactaaaatt aacgacgcaa gcctaaacgt ttgatcaatt cgcggtaacg
    12661 ttgaacgtca gttttacgta agtaagctaa caagttacgg cggtgaccaa cttttttcat
    12721 taggccgcgg tatgaatgat ggtctttttt gtgcacgcgt gcatgttcat tcaagtggtt
    12781 gatttcttca gttaatacag cgatttgtac ttctggagaa ccagtatccc cttcatggcg
    12841 agcgtattcg ttgatgattt cattcttgcg ttcttttgaa attgccattt ctttcacctc
    12901 tttcgattat tcccctgcga ctgagtaaaa cgttggtgat tcgcttaacc aagtggcagg
    12961 tcatgtgcct agagcacaca gctatacttt acctgaaacc gggttgaaaa tcaagtagtt
    13021 aatcattaag aaaaggtagt tttcaaacaa tcttactact acttttccat ttttgtggta
    13081 aactataatg cgaaaataga cttgaaacac agtcttttaa gaaaggggta catattccat
    13141 gattacaatg gatgatatca ttcgtgaagg aaatccgacc ttacgcgaag ttgcaaaaga
    13201 agtttctctt ccattaagcg aagaagatat ctctttagga aaagagatgc ttgagttctt
    13261 aaaaaacagc caagatccaa tcaaagctga agaactacac ttacgaggcg gtgttggctt
    13321 agctgctcct caattagata tttctaaaag aatcattgct gttcacgtac caagtcctga
    13381 cccagaggca gatggacctt ctctaagtac tgttatgtat aatcctaaaa ttttgagcca
    13441 ttctgttcaa gatgcttgtt taggggaagg tgaaggctgt ttatctgttg atcgagaagt
    13501 accaggatat gttgttcgcc atgccaaaat cactgtgtct tattatgata tgaatggtga
    13561 aaaacacaag attcgtttga agaattatga atcgatcgtc gttcaacatg aaatcgacca
    13621 tatcaacggt gtgatgttct atgaccacat caacgatcaa aatccatttg cactaaaaga
    13681 aggcgtattg gtgatcgagt agagaattgg caggttcctt cgatactatg ctacaagaaa
    13741 gctttataaa aaaggggagt gctcaaaagc tgcacttccc ttttttatgt ttctccacta
    13801 atcgaaattt agatagacat ctagaaatcg caattccaaa aaattctgtg tattggatac
    13861 gcatcttttc ttattttttc ttatttcttc catatgggtg tttatctcag agatgataga
    13921 atagtttcta ggataaaaag tagcagctac gatgttatcc ttcgtagagg attcctgctt
    13981 cagctagttt ttgtttgatg tttttcagca tatgcttttc tgggtagcgg atcgtatgca
    14041 gatggatgcc gcctgttaat tcggataaca aagtagcatt acttttttga taacgtctca
    14101 taaaggaatc gatatcttgt ggcgttttga tgtgcaaagt tcctgctaac tcaccgtaaa
    14161 ggggatgttc cacaattaca tcaatgattt caccaccatt ttcaacgatt agtctcagtt
    14221 cttcttctgt ttgatctttt ccatgctgga cagcgatttt actgatgtgc ccagtattgg
    14281 tttcttctgt ttcgaggata taacctcttg ctgttgccac gatactttta cctgcagctc
    14341 gtagtaaagc aatatcgcct acaatgatct gacggctgac tccaaaagtt ttcgcaaact
    14401 tgctagcact cactggtttt tctgtatttg ccaaggtttg catgatttgt tttcgccgtg
    14461 tctctccttc gatcacactt attcctcctt cattttgttt tggtattcgc gcgagtgttt
    14521 catcaaatca acatacgtgt ctgttattgt ttccttatat cccttatttt tcagcagact
    14581 aacaacttta tccaatactt gctgctctct ttttgcatca taaactgctt ggttttcttc
    14641 ttttttcact tgtcctattt tagttaccgt atccattctt ttttctaata aagcaaccaa
    14701 ctctcgatcg atcatatcga tcttatgacg taatgtttca agagactctt ctgttagttc
    14761 ttcctctact gtcttgatga tacgagcagg atttcctgca atcactacat tgtcgggaaa
    14821 agatttggtc acaaccgaac ctgcgccgac tactacgttg tcccctagag tgacacccgg
    14881 cgtgacgata actcctccgc ctaaccaaac attattaccg attttaatgg gttttgcgta
    14941 ctccagaccg ctgttacgtt tcactggatg tagtggatgc gtcgccgtgt aaagctggac
    15001 attcggagcg aacatgcagt tatcaccgat ttcaatcgtg ctgacatcta aaaatgtaca
    15061 attgaaattt gcataaaaat tctccccaac aaatatatta tatccgtaat caaaattgat
    15121 aactggctcc atatagattt ttttccctgt acggccaaaa gtctctttca acaattggga
    15181 tcgcagttcc gctgattctg cttggttgat gatttggctt tgacttcttg caaacatacg
    15241 gtcggcaacc agctcaggat cattggcaaa ataaagctcg cctgcaatca ttttttcttt
    15301 ttcggttttg aattcagtca taatctgctc ctaattcttg tatttttttg aaaacaaccg
    15361 ctccgtcttc ttgaataaac gtataaggct ccgctaaata aacaggcgtt tgattgatta
    15421 ctaagatttt ggctgacggc tggcgaaact gtaccagatc acaaaacgga tgaacttgaa
    15481 aactcgttcc aacaatgacg atcagctctg cttggctgac ggcataagcc gcctgctcca
    15541 tgactccatc ttgaaaccct tcaccatata acacgatgtc tgggcgtatt tgtcctccgc
    15601 atgcttgatg tttgtcgctg tgaagatatt ctttccagtc taccgtttgt tgacattttc
    15661 gacaatgaca ttgatacaga ctcccatgaa aattgacgag ttgcgggctt ttagcctttg
    15721 cgtgcaaacc gtcgatgttt tgggaaacaa cccaaacatt tttttctttc gctagatgtg
    15781 ctatttccaa atgaatgata ttgggttttg cttcaggatg ataaatcttt ttgacaaatt
    15841 gatagaattt atccggttca ttcaccattg cttgatgact cagcaagtat tccggctgct
    15901 ccatcccgtg gtagattcct gacaaagatc gatagtctgg cactccagaa ggtgtggata
    15961 cccctgcacc ggtcaaaaat gtaatttgct gataagctaa tatctctttt gctgcttcgt
    16021 ctactgttaa ttgtttcatg ttttgtcacc tcactttcca ttatagccca tactcgaaca
    16081 aatttattgt tgaaaagtca gaaaaatggg aataaaaaag tgttatgggc atttgagcaa
    16141 tttatcacaa tgttcactga caaaagaatg aaaacgtgtt acaatactgc tgtataaaag
    16201 tgaggtgaat cgatatgtta ccattcttta tttattgggg cgttattctg gcttgtatcg
    16261 cctggttagc gttaagcgtt tatttctctg ttttttatct tgtacgcaaa gaaaatggaa
    16321 atctttgggc ttttgcttta ttcaacgtga ttgccgcaat tgttttagcc attacattag
    16381 ccgtatatcg aacatggggc tggggaatca cccaatactc aagtttgatt tatctaatat
    16441 tagccattta tggcgtcgtt gttcttttgc aagcgatcct aggacgtgag ccaaagaaag
    16501 cggcagctta aatgatcgag atggaactgg acacaggaaa ttttctgttc tagttctttt
    16561 tttattgtat tacatacatt tttgtgtata attatactat cgtttgcaat ggatagatga
    16621 ttcacatttt gattgttttt tcggtaaaag taaagatttc tatatttatc agtatttttt
    16681 caaaaaccag cagttataga ttgacaaagc ctctcgagta tcgtaaactt tttttgtata
    16741 aataactgaa tacgagatgc ctcaatcaat gaggtagagg tcgcgagaat cattaaccct
    16801 gtggagtgaa gcaaacatgg agaagcagga atagggagga tcgccgaaat gtgcactttt
    16861 ttgcttggag tgtatgttgg gacgcaagtt aagagcttgc ggactgtctt agcagtgatg
    16921 ctaagttgcg ctatgttttg tgagaggttt atcaccttat ggaattttag cggccttttt
    16981 atatctataa atcggtcgct ttttattttt tcagataaag ctttaccgca tttcatctag
    17041 accgctcgtg tatcatataa tcagaaaggg agaaaaaaat gaaaaaaaat atggtttcag
    17101 ttgccgtact atttgctttt gtcttctcac tattcagtgt gggatctctg gcaaatgcag
    17161 atgaaaaaac accgagcgat gagtttcgcg taggtatgga ggctgggtat gcacccttca
    17221 actggtctca acaaacagat gagaataatg ccttgccaat tcaaggccaa aatagttacg
    17281 ccggcggtta tgatgttcaa atcgctaaaa aagtagcaga tggtttaggg aaaaaattag
    17341 tcatcgtcca aacgaaatgg gatggtctgg ctcctgccct tcaatcaggc aagatcgacg
    17401 cgatcatcgc cggaatgagc cctactgctg aacgacgaaa agaaattgat tttaccgatc
    17461 cttattacga atcacaatta gtagtagtag ttcaaaaaga tagcaaatat gcaaaagcaa
    17521 aaagtttagc agatctttct ggagcaaaga tcactgctca gttaaataca ttccactata
    17581 ctgtgatcga tcagatacca gatgtgcaga aacaacaagc aatggataat ttctcagcaa
    17641 tgagaacagc tttagcttct ggaatgatcg atggttatgt cagcgaacgt ccggaaggtg
    17701 taacggcaac tagtgtgaac aaagacttgg aaatgcttga attcagcggt gcagatggct
    17761 tccagacaaa cccggaagat gttcagattt ctgttggtat gcgtaaaggc gacccggata
    17821 tccaaaaagt aaaccagatt ctttctggca tctctaacga tgaacgaacc aaaattatgg
    17881 accaagcagt caaagatcag cctgctgcaa ctgatagtga agaaaaacct ggcatcattt
    17941 ctgatttcac tacgatttgg aaacaatacg gcaatatgtt cttacgaggt gctggactta
    18001 ccttgttcat cgcattgatc gggacagttg tcggtactac acttggatta ctgattggtg
    18061 tcttccgttc ggtacctgaa tcaggaaatg cactgactcg cttcttccaa aaaatcggaa
    18121 atgcacttct ttctatctat gtcgaagtat tccgcggaac accgatgatg gtacaagcaa
    18181 tggtcatctt ctacggtctg gcactcgctt ttggcatttc attgaaccga acgattgccg
    18241 ctttgtttat tgtctctctc aatactggag cttacatgac agagatcgtt cgtgggggga
    18301 tttttgcagt agatgaaggg cagttcgaag ctgcgcaagc cattggtatg acccatggcc
    18361 aaacgatgag aaaagttgtt attccacaag ttttacggaa tatcttgcca gcaacaggaa
    18421 atgagtttgt tatcaatatc aaagatacag cagttttaag tgtaatcggc gtagctgatt
    18481 tgttcttcca aggaaactct gcttccggtg cgaatttcca attcttccaa acatttacga
    18541 tcgtcgggat catctactta gtcatgacct ttacgatcac cagaatcctg cgggcggtag
    18601 aaaagaaaat cgatggtcct tcagcttata ccaagcttga agaaatcgac aattcaaatt
    18661 tgcaggaata aggaggaaga atcatgaatg aaaaaattat tgaaatcaaa catctaagaa
    18721 aaagcttcgg tgaaaatgaa gtattgaaag atatcagcgt aacagtcaat aaaggtgaag
    18781 ttgtgacgat catcggttct tccggttctg gtaaatctac tttcttgcgc tgtatcaatt
    18841 tactggaaaa accaacaggc ggcgagatca tttataatgg agaaaatgta ttagctccta
    18901 aatataattt acctaaatat cgaacgaatc taggtatggt tttccaatcc ttcaacctgt
    18961 tcaacaatat gaatgtcttg gaaaactgta tgtctggtca aacaactgtc ctgaaacgag
    19021 ataaagaaac tgccaaaaaa gtagcaatcg aaaatctgga aaaagttggt atggatcgtt
    19081 atatcgaagc caaaccagca caattatctg gtggacagaa acagcgtgtc gcaattgctc
    19141 gggcattatc aatgaatcca gatgtattgc tattcgacga acctacttcg gcgttagacc
    19201 ctgaaatggt tggcgaagtg cttaatacga tcaaagactt agcacatact ggcttgacaa
    19261 tgcttatcgt gacgcatgag atggaatttg caaaagatgt atctgaccgt gtcattttta
    19321 tggataaagg tgtgattgca gaagaaggta caccagaaga tatctttgtc catccgaaag
    19381 aagaacgtac aaaagaattc ctttcacgta ttttaaatgc ttaggatcaa tagctgattg
    19441 ggacaaagag ctgcggtgtt taccgcagtt cttttttatg aattactcat aaaaggtaaa
    19501 tttctgaaaa ttttggaatc ttagttgtgt ttttcagaaa actctcttaa tatggaagta
    19561 attaaacttt tttagttagg atgatttaaa aatgaatgaa gagcaagaac tgcagcgtgg
    19621 actgaaaaat agacatgtcc aactgatttc tattggcgga gcgattggaa cggggttgtt
    19681 tttaggttcc ggaaagtcta tccagctagc tggcccttcg atattgctcg cctatcttat
    19741 tactggatgc atctgttttt tcattatgcg tgcgttaggc gaacttctgt tatcaaacac
    19801 caataaccat tcttttctgg attttgttgc agaatatctt ggcaaaaaag cggctttcat
    19861 cactggctgg acgtattggt tctgctgggt atcgattgca atggccgatt taacagccat
    19921 cggaatgtat gtacgctact gggcgcctgg tgttcctcag tggcttcctg aactgattgc
    19981 attaggtctt cttctttgct tgaatatggt ggctgtctca ttgtttggtg agttagagtt
    20041 ttggtttgca ttgatcaaag ttgtagcgat cattgccttt atcctcgtag gagcttatat
    20101 gatcctcacc cactatacga cagatattgg cacagccagt atcacgaatc tatggtctca
    20161 tggcggattc tttccaactg gtgcaaaagg atttatctta gctttccaaa tggtaacctt
    20221 tgcttttgct gggatagaat tagttggatt agtcgctgga gaaacagaaa atcctgaaaa
    20281 agtgttgccg gaagctatca ataatattcc tatcaggatc atcttatttt acttaggatc
    20341 tctttttgtc attatggcaa tctatccatg gaacagcttg aatccagata acagtccatt
    20401 tgtagaagta ttttcggaaa ttgggatcac gattgctgct tccttgatca atttagtcgt
    20461 attaagtgca gcagcttctg cctgcaacag tgcaatatat agtacaggac gtatgcttcg
    20521 ttctttagcg caagaaggca gtgcccctaa aaaattcaaa aagttaacaa cacatcatgt
    20581 gccagggaat gctttgacat tttctactat cgtcattttc atttctgtta tcttgaatta
    20641 cgtgatgcct agtgaagtat tcacactagt aagcagtatt gccactactt gtttcttgtt
    20701 tatctggagt atgcttgtct acacgcacat gaaatatcgt aaaagtatcc tcggcaaaaa
    20761 agctcattca tttaaaatgc cgttgtaccc atttagtaat tatctggtat ttctttacat
    20821 ggcctttgtg tgtgtcgtct tgttcctagg aaaagatacg agaatcgctt tattactaac
    20881 acctgtgtgg ttcttgcttc tattactaat ctatcatatg aaatatgaac gtaagaagta
    20941 agaaagtagt tgtgacagaa gtggtcagct tcgagaaata agaaggaatt tacgaaaatt
    21001 gcttcttaaa tttttgtgaa atttcggctt atttcttgga gataaaagct tctgtcccag
    21061 cctcttttct atttccccgg aaacaaccgc tgataatagg catctgcttt tttataggaa
    21121 aaaatccaaa taccagatac aaaaaaacgt ccgaataacc cgatcaacgg tacaaaaaag
    21181 acaccggcaa tcaagcataa gttaatcatc atggagataa gacttcgacg gtcctttgac
    21241 aaaactctca cgacatggga atctggttta tttgctttca tgatttgcct catcaagata
    21301 ccaaaagaaa aactccacat cgtgtatact aagacataag ccatctcagg ccaaaaagct
    21361 tcagggttac gcccgaccca actagtaaca gaaggacata aagtcagcca aaagagcaaa
    21421 aagatattcg accagaccac tcggtaatta attcgttctg ccatctgaaa tatacgatga
    21481 tggttcaccc agatcaccgc aacaaatata aagctgatgg tataagctaa taatgtattt
    21541 cggatgaccc ataaagaatg aaagctagat gtattaggga tcttgatctc taatacaata
    21601 actctcaaaa caatggctac cactccatca gtaaatgctt ctaatctcga ctttgtcacg
    21661 atgattcctc ctcagatgat tcagcgcttt tattttatca cttacgttat taaataacca
    21721 tcgttttata tagggaattt tctgaaaatt gttgcatatt tttcgaaatt ttgttacttt
    21781 taaaaaaacc gtaaaggagt tatgtatgac aaaaaaatta tcatttaaag actatctttt
    21841 tataggctcc atgcttttcg gtctattttt tggtgctgga aatcttatct ttcccgttca
    21901 tttgggtcaa gaagcaggcg ctgctacctt ttgggcgaat ctaggtttct tggttaccgg
    21961 tatcggtctt cccttcttag gggtgattgc cattggtgta tcgaaaagct caggtgtata
    22021 tgaattagca aaacggataa atcaaacata tgcgatggtt tttaccatct tgctttactt
    22081 agttatcgga ccgttttttg ctttacctcg ccttgcaacc acatctttcg agattggttt
    22141 agcaccattt atcgatccta gcagacagac gctatatcta gcaattttca gtattgtatt
    22201 ttttgtgctg gcttggtggt tttcaagaaa accgacaaag atattagatt atgttggaaa
    22261 gttcctgaat cctgcatttt tggttttatt aggtgctttg cttctccttg cttttttgaa
    22321 tccactaggt tctgtaaatc aagcgcctat tcagccaaat tatcaagagc atgctttttt
    22381 cacagggttt actcaaggat ataacacatt agatgcgctt gctgctttag catttgggat
    22441 catcattgtc acaacaatcc aaaacatggg tgtaacaaaa cctgctgaaa tcgctaaaga
    22501 cacgatcaaa tctggtgcga tcagcattat attgatggga atcatttata ctttgctcgc
    22561 ttatttaggt gctatgagct taggtagctt tgctctaagt gaaaatggcg ggatcacgct
    22621 ggctcagatt gctgatcatt atttaggtac ttatggcagt atcttattag catttatcgt
    22681 tatattagct tgcttgaaga ccggtattgg tttgattaca gcttttgcag aaacattcac
    22741 agatttgttt ccgcaaagaa attacgcatt ctttgttgca cttgctagta tccttccttg
    22801 tttagcggca aacgtaggct tgacgaatat cattcaattt tcgttgcctg ttttgatgtt
    22861 catctatcca ttagcaatga cactgatttt actagtgtta gttggtcctt tgtttaagca
    22921 gcgtacggct gtttatcgaa tgactactta ttttacattg attgcttcga tttttgatgg
    22981 gttgaacgct tgcccagaaa ctatcaaaca aacacctatt gttcaaaatc ttttatatgt
    23041 tgcggaaagc tacttgccgt ttttcaaatt ggggatgggg tggatcgtac cagcagttat
    23101 cggttttgtt atcggactga tttggagttt cgctaagaaa gaagaagtag cagattgata
    23161 aaagaggttg tgaaagagac gttcagcctt gagcaataaa aagtaatttt gaaaaatggc
    23221 ttctcacatt tttgcataaa tttgacttaa taccgagaaa ctgacttttg aacaccgttt
    23281 attgagaggt cgtgaaaaag ccgcttagtt tcaagtatta agaaatattt tgtgaaaatg
    23341 gcttctcaca tttttgcata aatttgactt aataccgaga aactggcttt tgaacaccgt
    23401 ttattgagcg tctataaact gacctgagta ttagagaaac aaaacggcaa agtagctcca
    23461 tatactttgc cgttttgttt tgaactaata ccgaagagaa gctgatcaaa caacatttct
    23521 tttataatat agattttaga catatatatg atataaaaat agttttcgca aaa
//
LOCUS       DADVXM010000038        23420 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.039, whole genome shotgun sequence.
ACCESSION   DADVXM010000038 DADVXM010000000
VERSION     DADVXM010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.039"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            56..1717
                     /locus_tag="KB927_001558"
     CDS             56..1717
                     /locus_tag="KB927_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6840479.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(1787..2134)
                     /locus_tag="KB927_001559"
     CDS             complement(1787..2134)
                     /locus_tag="KB927_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBB6840480.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2218..3159
                     /locus_tag="KB927_001560"
     CDS             2218..3159
                     /locus_tag="KB927_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6840481.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3160..4203
                     /locus_tag="KB927_001561"
     CDS             3160..4203
                     /locus_tag="KB927_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6840482.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4209..5279
                     /locus_tag="KB927_001562"
     CDS             4209..5279
                     /locus_tag="KB927_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840483.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5269..6222
                     /locus_tag="KB927_001563"
     CDS             5269..6222
                     /locus_tag="KB927_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6840484.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6234..7244
                     /locus_tag="KB927_001564"
     CDS             6234..7244
                     /locus_tag="KB927_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6840485.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7529..8350)
                     /locus_tag="KB927_001565"
     CDS             complement(7529..8350)
                     /locus_tag="KB927_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6840486.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8447..8725)
                     /locus_tag="KB927_001566"
     CDS             complement(8447..8725)
                     /locus_tag="KB927_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840487.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            8993..11002
                     /gene="metG"
                     /locus_tag="KB927_001567"
     CDS             8993..11002
                     /gene="metG"
                     /locus_tag="KB927_001567"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBB6840488.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11481..12068)
                     /locus_tag="KB927_001568"
     CDS             complement(11481..12068)
                     /locus_tag="KB927_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840489.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12243..13565
                     /locus_tag="KB927_001569"
     CDS             12243..13565
                     /locus_tag="KB927_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6840490.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13720..14496
                     /locus_tag="KB927_001570"
     CDS             13720..14496
                     /locus_tag="KB927_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBB6840491.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14489..15058
                     /gene="rnmV"
                     /locus_tag="KB927_001571"
     CDS             14489..15058
                     /gene="rnmV"
                     /locus_tag="KB927_001571"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBB6840492.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15051..15935
                     /gene="rsmA"
                     /locus_tag="KB927_001572"
     CDS             15051..15935
                     /gene="rsmA"
                     /locus_tag="KB927_001572"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBB6840493.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16386..17015
                     /locus_tag="KB927_001573"
     CDS             16386..17015
                     /locus_tag="KB927_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840494.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17139..18248)
                     /gene="ugpC"
                     /locus_tag="KB927_001574"
     CDS             complement(17139..18248)
                     /gene="ugpC"
                     /locus_tag="KB927_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBB6840495.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18457..18879
                     /gene="mgsA"
                     /locus_tag="KB927_001575"
     CDS             18457..18879
                     /gene="mgsA"
                     /locus_tag="KB927_001575"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBB6840496.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19202..19738
                     /locus_tag="KB927_001576"
     CDS             19202..19738
                     /locus_tag="KB927_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBB6840497.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(19778..21541)
                     /locus_tag="KB927_001577"
     CDS             complement(19778..21541)
                     /locus_tag="KB927_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840498.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21544..23259)
                     /locus_tag="KB927_001578"
     CDS             complement(21544..23259)
                     /locus_tag="KB927_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840499.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT         7544 a         4291 c         4767 g         6818 t
ORIGIN      
        1 aacaacttca gaaaatatta attattctga aaattccaat aaaggggtac gtaaaatgaa
       61 aaagaaattt acatttggtt tggttgcggt atgcggcctt gtacttgctg gatgttatgg
      121 cggcagttca gccacaagca gtagttcagc aaaaagcggt tcagcagatg gaggaggcgt
      181 atttaactta gtcgtgcctc aagaaatgcc tacagctgac ttatcagttg caacagatac
      241 aatcagtttt acagcattga ataacgttta tgaaggaatt taccgtcttg atgaagacag
      301 caaaccacag ccggcaggag ctagcgagtt ggcagaagtc agtgaagacg gattaactta
      361 caaaatcaaa ttacgagaag acgcaaaatg gtcaaatggt gatcctgtta cagcagcgga
      421 ttacgtttat ggctggcaac gaacagtaga cccagctaca gcttctgaat atgcttacct
      481 gtatgcgcca gttgaaaatg cagaagacat tacagctgga aagaaagata aatcagaact
      541 agggatcaaa gcagttggtg actatgaatt agaaatcaaa ttgacgaaac aaacaccata
      601 tttccaatat ctgcttgctt tcccatcatt tttcccacaa aaacaatccg tagtggaaga
      661 aaatggggat gcctatgcat ctgcaagtga taaagctgtt tataatggac cattcacatt
      721 agaagatttt gatggaccag gaacagatac agaatggact tataagaaaa atgatcatta
      781 ctgggacaaa gatacagtaa aactttctga aatcaaagtc agtgtagtaa aagaatcttc
      841 tactgcattg aacttattca aagatggcca agcagatgac gtgatcttgt ctggtgagtt
      901 agcacagcaa aacgcaaacg atccagctta tacttctgtt aaagaagcgc ggacaagcta
      961 tatcgaattc aatcaacgtg aaaagaattc accattcaac aatgtgaacc taagaaaagc
     1021 tatttcttat tctatcgatc gtgaagcttt agtaaaacaa gtactaggtg acggatcagt
     1081 tgtctctaca ggattgatcc catcagatat ggtaaaaagt ccaacaacga acgaagactt
     1141 tgcaaaagaa gctggaaaat tagtttctta tgacaaagat aaagcaaaag aatattggga
     1201 aaaagcgaaa aaagaattgg gcgttgattc tttagaattt gatttgatgg cttctgatga
     1261 tgattcatcg aaaaaagtaa tcgaatatgt tcaaaactca atccaagaaa acttggatgg
     1321 cgtaacagtc aaaccaacac ctgttccatt ctctgtacgt cttgaccgct caacttcggg
     1381 tgattttgac gcagtactag gcggatgggc tgctgactat gcagacccaa gcagctttac
     1441 tgatttgttt gtcacaggta attcatacaa ccgtggtcgc tggagcaatg cagaatatga
     1501 cgaagcagtt aaagcagctt catcaacaga cgctggcgat gaacaagccc gttgggatga
     1561 tttccaaaaa gcaatcaaga tcatctctga tgatatgggt gtcgttccgg tgtaccaaaa
     1621 agcagaaggt cacctagtga atgaaaaaat caaaggtatc gttcaccatg cggcaggcgc
     1681 ttcatgggat tacaaatgga catacgttga agaataatcg ttaataccgt gagcatgaga
     1741 aaaaacgagg ctgcggcaaa tgtcgcaacc tcgttctcat attcacttat cctaacaaag
     1801 aaaaaagcat gaaaatagca gaaagagcaa ttagtattcc ggcaatgatc agccaaaagc
     1861 tgtacatacc gtagctggca gacgagagcg aggaaaattc tggttttttc tttcggttcc
     1921 ttgttcgtgc aagatggacc gatcgctgaa aatgatcgaa gaaacccgaa gaaaagaccc
     1981 ataaaaaacc gccgataatc agaaacggca atgaccataa gaatagatca ttagataatt
     2041 gaatgagtgt aaaggaatgg ttgatgagat tttttattaa aataaccaga atcagtagaa
     2101 aagctactgc gtaggggata gatttttttt tcatttgatt gctcctttat ttttggttca
     2161 ttatctaata atgtagcgaa acatctgtca gaagtcaaaa gctaggggga aacattagtg
     2221 aatagttata tcaaatatgt attaaaacgt gtctttttca tgatcatcac gctttggtta
     2281 attgcaacaa tcaccttttt cttgatgcaa ttgctgccgg gcacgccata tacgaatcag
     2341 gaacgtttga gtcctgaaac aatcgagatg ctaaataaac aagtcggttt ggataaacca
     2401 gttatcgtac aatatgggat ttatctttct aatttgcttc aaggagattt tggaatttcc
     2461 ttccaattta aaaaccagcc agtcgcacat ttgttagctg gaagaatcgg accatccttg
     2521 cagttagggt tacaggcaat tatctttgga acagtcctag ggacgatttt aggaacgatc
     2581 tctgccatga agcaaaatac atgggcagat acatcttcta cactcgtagc gatattaggt
     2641 cgttccattc caaactttgt atttgctgtt ttattacaat atatctttgc aatcaaatta
     2701 caagttttgc caatcgcaaa atgggatggc tttgtgtaca caatcttacc aacaattgcg
     2761 ttggccatgt cgccgcttgc tgactctgct cggtttatcc gtacggaaat ggtggaagta
     2821 ctgcatagtg attatgtgga attagcaaaa gcaaaaggat tgagccgttg ggaaatcgcc
     2881 tttaaacatg gtcttcgaaa tagtttgatt ccattgatga ctttattagg accgttagct
     2941 gtagcattga tgaccggatc actggtggta gaaaatatct ttgctattcc tggtatcggg
     3001 gaacaattcg ttaagtcaat cacaacaaat gattatccta cgatcatggc tgtaacgatc
     3061 ctttactcat ttatgctgat ttttgttatt ttgatcgtgg atctattgta cggtctagtt
     3121 gatccaagaa ttcgtgtttc agaagggagc cgaggataaa tggaaatgat accaaagcgt
     3181 tatgaaacag ttgcagatat ccctgcggat gaatttcttc cattacaaaa aaataccgaa
     3241 gaagaacgtg aacagattac tgcaccttct ttgaatttta tccaagattc atggcgccgt
     3301 ttaaagaaaa acaaagctgc cgttatttca atggttttac tattggtcat cattttgatc
     3361 tctgtgatca caatctttgt ttctcctcat gatccaactg cccaaaacgt ggcttatatc
     3421 aatttgcctc ctcgtattcc gggaatcaat atcgatggat tgaatggaaa agcaatggtt
     3481 ggtggtgaac ttgttgataa atatgctcaa gcaaacgtcc cttcaaacgt aaatttcttt
     3541 ttaggaacag acggtttggg acgtgatgta ttaagccgct tatttatggg aatgagaatc
     3601 tcgttgctga tcgcatttat tgctgcatta ctagatgtaa cgattggtgt agcttacggg
     3661 ttggtttctg gtttgttagg cggacgtgtc gataacgtga tgcaacgttt tttggaaatc
     3721 ttatcaggaa ttccaaacct cgttgtcatg attttgatgt tggtcgtttt tgaaccagga
     3781 attttttcaa tcgtggctgc tatggccatc acaaactgga taccaatggc acgtatcgtt
     3841 cgtgcacaaa caatgaaatt aaaagatcaa gaatatgttt tagctggatt gacattaggt
     3901 gaatcaagaa tgaaaattgc attcaaacat attttgccga atatctctag tgtcattatt
     3961 attcaaatga tgtttagtat tccatctgct attttcttcg aagccttttt aagctttatc
     4021 ggtttaggtc ttacgcctcc gtcagcttca ttaggaacga tgttgagcga agggtacaag
     4081 acattcctgt atctgcctta tctattatgg attccggcag taactttatc ggttatcatg
     4141 attggcttta acttacttgc tgatggattg cgtgatgcct ttgatcctaa aatgaaagag
     4201 tgaagacgat gacgaaaatt ttagaagtga aagacttaga aatctctttt gatacgtatg
     4261 ctggaaaggt acgagcgatt cgcggtgtca attttcattt gaataaagga gaaacattgg
     4321 cgatcgttgg ggaatctgga agtggaaaat cagtgacgac cagaagcatc atgcgcttgc
     4381 tgtcaagcaa cgccaatata gatgctggtc aaatcctctt taaaggtaac gatatcgttg
     4441 gaaaatcaga aagagagatg caaaaaatcc gtggtaaaga aatagcgatg attttccaag
     4501 atccaatgac ctctttagat ccgacgatgc ccattgggaa gcaagtcgct gagtccctta
     4561 gaaagcataa taaagtttca aaaaaagagg gacaaaaagc tgcattagaa ttgcttaaat
     4621 tagttggaat acccgaagct gagaaacgta tcaacagtta tccgcatcag ttctcaggag
     4681 gtcagcgtca acggatcgtg atcgcgattg cactggtatg ttatccggaa atcctgattg
     4741 ctgatgaacc tacaacagcg cttgatgtga ctattcaagc acagattttg gagctgctga
     4801 aagaaattca gacaaaaatc gatacatcaa ttatctttat cactcatgac cttggtgtag
     4861 tagcgaatgt cgctgatcgt gtcgctgtca tgtatggagg aagaatcgtt gaagttggaa
     4921 catcggaaga aattttctac aacccgcaac atccctatac ttggggactg cttggttcaa
     4981 tgccgacatt agatagtgcg aacgatcgat tgtatgctat tcctggttct ccaccggatt
     5041 tattgaaccc gccaaaagga gacgcattct atccaagaaa tgaattcgcg atgaaaatcg
     5101 atgcagaaca agaaccacca ttttttgaac tatcaaaaac acacaaggca gcaacttggc
     5161 tacttgctcc gcaggcaccc aaagtgacac cgccagaaga aatccaacgt cgctgggcta
     5221 tctttaaaga gaaacaaaaa catacttacg gtcaaggagg aattgctgat gccaaataaa
     5281 ctacttgaag ttaaaggatt gaaacagtat ttcaatgtag gaaaaaagaa tgaagtacat
     5341 gctgtaaatg acatcagctt tcacatttat gaaggagaaa cattcggttt agttggagaa
     5401 tctggaagcg gaaaatccac tactggccgt acgatcattc gcttgaatga acctactgat
     5461 ggtgagatat tattcgacgg tcaagatata acgaagatca aagataaaaa aggtttgacg
     5521 aaattccggc atgatgttca gatgatcttt caagatccat acgcttcgtt gaatcctcgt
     5581 atgaaagtca gagatatcat tgccgaagga attgatgtta atggactagc taaatcatct
     5641 gaagagcgtg caaaaaaagt cgatgatcta ttgagaactg ttggattgaa tccaagccac
     5701 ggtactcgtt atcctcatga attttcaggt gggcaacgcc agcgtattgg tattgcacga
     5761 gcattggcag taaaaccgcg ttttatcatt tgtgatgaac caatttctgc actagatgtg
     5821 tcgatccaag cccaagtggt caatttgttg caagatctcc aaaaagaaca tcaattgacc
     5881 tatctattta ttgcacatga tttgtcgatg gttaaacata ttagtgaccg aatcggtgta
     5941 atgcataacg gcttgttatt agagatggga acaagtgatg aaatctataa tcacggtgtt
     6001 catccttata cagaaagttt gttatctgct attcctctac cagatccaga ccatgagaga
     6061 aaacgcagaa gaatcaaata tcaacctgaa ccagatgacg gacaagtacg tcaacttcgt
     6121 gaaatcgcac cagaacattt tgtctatgca actgagcagg aagtcccata ttacgcaaaa
     6181 aaactaaaac gacaaaagga atctcttctg gttgctaact aggagggaca tagatgctaa
     6241 aagcttttaa attccgtatg tatccgacag aagaacaaaa acagcaattg attcgtactt
     6301 ttggatgtgc tcgatttacc tataaccatt tgctgaaaaa gcggcagaaa agttggcaac
     6361 aaacaggagt agccaatttt tcgctcacac ccgctacatt aaaaaaagaa tacccattct
     6421 taaaagaagt agacagtctt gctttagcaa atgcacagct taatttggat cgggcttttc
     6481 gcaattattt caagggacgt gccagcttcc caaagcttaa aacgaaaaaa agtatgtggc
     6541 aatcttatac gaccaacaac caaacccgta cgatctatct ggaaaatggc tacttaaagt
     6601 taccaaaaca aaaagaacta atcaagataa atcagcatcg gccagttgaa ggatcgattc
     6661 gctccgctac gatttctgct cgatataatg aagaatttta tgtcgcacta ctttgtgatg
     6721 tttcgccagt aaaaaaagaa tctttagcta aatggatcgg gatcgcctat catccgaaga
     6781 cattgatcca aacatctcga cctctagaag taactttacc aaaatttcac cagacagaag
     6841 aaaagctgca acatgcacag cggaaattga atgtgaaagt ccgctccgct caccatagaa
     6901 agatcaggtt agatcaggca agcaattatc agaaacaaaa gagaaaagta atggatcttt
     6961 atctgaaaca aaagaaccag cgagaagatt atcttgaaca attatctggg aaattggtca
     7021 aacaatatga ctacttattt gtagaatctt ttccaaaaga agaggcacat gctgattttt
     7081 ctattcacga ctggcataaa ttaataacaa aattgcgtta taagtcccaa tggtataata
     7141 aaaaatttct tttgatcaat accgacggag cagaagaaag caattccgta agaaagagcc
     7201 aagtagtaga aaaaatgggc agacattcgg ttatcaaggg ataaaaaatg aatgaaactg
     7261 ataggagcgt tagggttagc cttgttaata aaaagtctta atgacttttg tttctaggaa
     7321 tttttctttt gaagaaaagc tcactaatta tgacaaacca ataaaacaat agcagaaaaa
     7381 gttcgtacga gctttttctg ctattgttaa ttttttattc agaaagttta cgaatacatc
     7441 aaaattctga aacaaaaaac gtaactcaca aagagttgtt tttgcgtttt ttcttgaatg
     7501 attaggtctg aatcttttgc tcacaacctt attcatggtg ccccggcttg agctgataga
     7561 tttttgaagg acggccgatt cctacaggac gttcaccgat ctcatcgaaa tattggagca
     7621 tagctttctt aaaattggaa tgatcgatcg ttttataatc gatccctaag aatttagcaa
     7681 atacttttcg agcttccgta atcgtgaaat ctttacctaa aacttgtaga acttgcggct
     7741 cgtgttccat tttattgact acacggttga atgctttcaa gatgatttga ctatggtcaa
     7801 aagccaaagt atctttgcca gaagactctc cagtgactaa atcaagcgag atagccactt
     7861 ctccgctaga taaatggatc ttgttactat gacgttctag tgtgaaccag cgtacttcct
     7921 tggcatcatc tccggcgatt agcggttctt ctccaataaa ggctaagtag ctgactgtga
     7981 cgacccagcc tcgcggatct cgattaggcg tactgaatgt atgcagttgc tcaatatttt
     8041 cttttgaaat aaccacacca gtttcttcct ttgtttctct taagacgctt tctccagttg
     8101 actcatcctt ttggacaaag ccaccaggca atgcccatga atttcgataa ggatgccctt
     8161 ttctttggat caacaaaact ttcagctgat cttcttcttt gttatagcac atcagtacga
     8221 tatcgacagt caaagagggc ttgtcatatt ctggacgttc ctgtttttga taccagttaa
     8281 gaaattcttc ttcacttgct ttatgttcat aatataattt ttcttcttct ttagaagcaa
     8341 aacggttcat ctgaccacct ccattgacag taaaagtact ttttacctta ttgtagcaga
     8401 ctctgaaaaa aaaccaagga tttacttgaa aaatctaggt tatcatttaa atatgaaaaa
     8461 taaatggaag tatgagattg aataaaaaga aaagcagata aaacggcaat actttatacc
     8521 gctcttcacg aatggcaaag aagccacaaa taacgatata tacgtcaatg ataaaacgca
     8581 aaatccaagc tgctgtcata aaactgttca aatgcccatg gaggttaaaa taaccataca
     8641 tacgaatata aaaatagctg aatattaaat gtgctaatga aagaaaagca atactaagtg
     8701 taaaaaaaag atgtttcttc tgcatgattg ttccagtccc ttactaagat agatagtctt
     8761 tattatacca cgtgtgaggg gagaaataaa aagccgtttt ttagtagata tgaaacaaaa
     8821 caaaaacccg catttattca acctattcat ccttttaaag gatagattga acgtagatag
     8881 aagtcgttta tccagtcttt ttcattttga aaaaaagcta acagcatgct ttttttatgg
     8941 tatactagca aggaaacgaa ttcgcatcat gcgataaagg aggaagagcc ccgtggcaga
     9001 aaaggaaact ttttatatca ctacgccaat ctattatcca agcggcaaac ttcatatcgg
     9061 caactcgtat actacgattg catgtgacgc aattgctcgt tataaacggt tgatgggctt
     9121 tgatgtgttt tatctcactg gagtggatga acatggtcaa aaaatcgaaa caaaagcaga
     9181 agaactaggt gtaaaaccgc aagaatatgt agataaaatg gcggctgatg tcaagaaatt
     9241 atggaaaacg cttgatatca gttatgataa attcattcgc acgacagatg attaccataa
     9301 agcagctgtt caaaaaatat ttgatcgttt attagaacag ggagatattt acttaggtga
     9361 atatgaaggc tggtactctg tttctgacga agaattcttt acagaaacac aacttgcaga
     9421 agtgtacaaa gatgacgaag gtaacgtgat cggtggtaaa gcgccaagtg gacacgaagt
     9481 agaattggta aaagaagaat catacttctt ccgcatgagc aaatacgcag accgtctatt
     9541 ggaatactat gaagaacatc ccgaattcat ccagccagaa tctcgtaaaa acgaaatgat
     9601 caacaacttt atcaaaccag gattagagga tcttgcagtt tcacgaacaa cttttacttg
     9661 gggagtacca gtcaagagtg atccgaaaca tgtggtgtat gtatggatcg atgcattatc
     9721 caattatatt actgcactag gatatggctc cgaagatgaa agtctattcg aaaaatactg
     9781 gcctgcagat gttcagatgg tcggtaaaga aatcgttcgc tttcatacga tctattggcc
     9841 aatcatgctg atggcccttg atttgcctct acctaaaaaa gtatttgggc atggctggct
     9901 attgatgaaa gacggaaaaa tgtctaaatc aaaaggaaat gtcgtttatc ctgaaatgct
     9961 tgtggaacgt tatggtttag atgcactccg ttattatttg cttcgtgctg ttccgtttgg
    10021 gtcagatggt gtctttacgc cagaagattt tgtttcccgt gtcaattatg atctggcaaa
    10081 tgatctaggg aacttattga atcgaacgat tgctatgatc aacaaatatt gtgatggact
    10141 cgttcctgac tatgcctcac ttgtcactcc atttgatagt gaactgtcta cgacggctgc
    10201 taacgttgtc ggacgttacc atgatgcaat ggaaaaaatg gaattcaata cagcattggc
    10261 tgaaatctgg gtgctgattt ctcgtgcaaa caaatacatt gatgaaacag aaccatgggt
    10321 attagcaaaa gacgaagaaa agaaagctga attgaatagt gtcatgatcc atttagctga
    10381 atctttgcgt atcgcagcga tattacttca gccaatcatg acagaaacgc cagagaagat
    10441 cttcaatcaa ctaggattgg actctgaaac aatgaatctt gaaggattac actttggcga
    10501 atttccttca ggaacaaaag tagttgcaaa aggtacacca atcttcccac gtttagatat
    10561 ggaagaagaa gttgctttta ttcaagaaaa aatgtctgaa ggtactcaaa caaacgaaga
    10621 tacagtcaaa tgggatccag aagaaacaga acttgtttca acgaaagaaa aacaaatcaa
    10681 atttgatgta tttgaaaaag tagaactaaa agtagcagaa gtcatcaact gtcaaaaagt
    10741 agaaggggca gataagttgc tgcaattccg actagatgct ggagacagcc aagaccgtca
    10801 aatcttgtca ggaatcgctg aattttatcc tgatccaagc gaattgatcg ggaaaaaagt
    10861 cgtcattgta gcaaatctga aaccacgaaa gatgcgtgga caaatcagtc aaggaatgat
    10921 cctttctgca gaagcaccag atggctcttt acaagtaatc gaagcaccaa aatccatgcc
    10981 aaatggctca gaaatcgcat agaaattcaa agggggtatg acactagttg tgtcataccc
    11041 cctttttccg aaatttgaga agcaattttc gtaaattcct tcttattact tgaagccaat
    11101 catataatac agaaacagag aactatccaa aataaatcct agaaaaagaa gtacgagctt
    11161 cgctgatttt tgttaattta gaataatact aataggaatc gtaaaaacag aaaaaaagca
    11221 taatgataaa gggtcgggca gattttaatt gattcatctg gtactctttt ttattgtcct
    11281 tacattcata aagtttgaat gcaatgactt tattacatct atatttatat ctaacagtag
    11341 cgttgatgtg ttaattataa gttctatcac tttatgttca attagtttgt gctcttatat
    11401 gtgtgattga aaatatagat aaaaaaacaa tcatcggctt tgacttcgat gattgttttc
    11461 tttattttgt aaaaatccta tcacttgatt ttatggtaac cttttatttt tgtcttcaaa
    11521 cggcttggta agagagcagt aagcagtgca aatgggatcg aaaagacata ccagaaaatc
    11581 gtacgtccga taccataatg ttgatagagc tttgtcaaca tcacgtgtaa caagatcaac
    11641 cctaaaagca aggagccagc tataaaccaa tgattatccc aatgcatgac ttcactaagt
    11701 gccatcactc caaaaggata gaaataaaaa tagatcccga ctaaggtcat ccgccagttc
    11761 tttgtaaatg ttccgatatt caataaaaag aaaatcgctg aaagcaaaat accgataggc
    11821 ggaaaaagcc caaccaaaaa ggaatacaac atcccccaca agatcatcac aggacctttg
    11881 atcaatgcaa cgattgcgat gaacaaagtc agcaatatta gtttttgtga taacgttgca
    11941 acagtcatta atccaaataa aattaatgtg aaccaatgcc aatgggactg ctgttgttct
    12001 ttacgggaaa aatcgacccg gttggataaa taatctgcta atttcggata agaacgctta
    12061 aaatccataa actgttcctc cttcgtggaa aaggtaggtt tagtatacga aaaataaaaa
    12121 agaaatacat ccgtcttaag agggagtttt tcactgaaag tggagaaaaa agaatggtaa
    12181 attaaaatat tctcagttat actgaaaatt ataccaaatt tcaaagaaga aagaggatgg
    12241 gaatgaaagg caaactaaaa cgagaaatca atctgtttgg cgcattagct accgttatgg
    12301 gaaccgtgat cggtgcaggc gtcttcttca aaactgctgc tgttactgct agtactcagt
    12361 ctacaagttt gacattgcta gcttggcttt tgggtggttt cttaacgatc tgtgctggat
    12421 tgacagtggc tgaattagct acagcaatcc cggaaactgg tggagctgta aaatatattg
    12481 aagctgcgta tggaaaattg cccagctttt tattaggatg ggcgcaaagc ttgatttact
    12541 ttcctgctaa tattgctgca ttatcgatta tctttgcgac acaattgacg aacttattac
    12601 aattatctac cgattatctt ttgttgattg cagtgatcac cgctgtttct gtgacagggt
    12661 tgaatttgtt agggacaaaa gtcggtgctt ctgtacaatc agtgacgttg attgttaaat
    12721 taataccaat tgctgtgatt gtcatatggg gattattgac cccaggacaa ggaactgtcc
    12781 agttatttcc aatcgaagct ggaaaagatg ttacttttgt cgaaggattg agcagtgcgt
    12841 tgttagcaac gttgtttgct tatgacggct ggttaggtgt cggtgcaatg gcaggggaaa
    12901 tgaaacggcc ggaaaaagat ttgcctaaag caattattct tggtttgagt tttgtaacag
    12961 tcgtttatct attgatcaat tttgtttttt tgaaaacttt gccgattgat catcttgccg
    13021 gtaatttgaa tgcagcttct gaagcatcag acgtcatttt tggaggaatc ggtggaaagc
    13081 tggtcactat tgggatcttg atctcggtat acggtgcatt gaacggttat acactaactg
    13141 ggatccgcgt gccttatgcg atggctttag aagacgagct acctttcagt aaacagctga
    13201 caaagctttc aaagaagttt acggttcctt atgttcctgc ggttttccag ttagcagtag
    13261 cttgtattat gatgagcctt ggttctttcg actttttaac agacatgttg atttttgtga
    13321 tgtggctatt cagtttactg atttttatcg gtgtctttat tttaagaaaa aaagcgccgg
    13381 aattgccacg tccatataaa gtaccacttt atccaatcgt tccgattatt gcgattctcg
    13441 gtgctatttt cattttaggt atgacgatga tgacgcaaac gaaattagca ttgatcggta
    13501 taggtgttac cttgataggt atcccagtct attatcaaaa aaagaaaaaa cgctcagaag
    13561 agtaaaatat ttcaacaaca gacagaaaaa gtacgaacta ggtcctctag atcttcgtgc
    13621 tttttctatt tcaataaaac aagttcttct attttgattt ttgctacttc tgcaagtagt
    13681 gcttatgtgc taaagtaaga atgaaaagga gagataaaca tgatatttga ttctcatacc
    13741 catttaaatg ctgaacagtt caatgaagat attccagaaa cgattcagcg agcacaagaa
    13801 atgggggtaa cgaaaatggc ggtcgtgggc ttcgatacgc caacgattga aaagtctttg
    13861 caattaagcc atgactatcc aaatatatac agtattatcg gctggcatcc gacagaggct
    13921 ggcagttata cgaaagaaat cgaaaataaa ttacaagaac aattgacttt accaaaggtt
    13981 gtagcattag gggaaattgg cttggattat cattggatgg aagacccgaa agaagtccaa
    14041 gataaagtat ttcgcagaca gattgctatc gcaaaagaaa tgaacctacc aatcagtatt
    14101 catactagag aagcacttga agacacgtat caaatcctaa aagaagaaga tgttcgagat
    14161 atcggtggaa tcatgcatag tttcagtggt gattatgaat gggcaaaacg atttcttgac
    14221 ttagggatgc atatttcatt tagcggtgtc gtcactttca aaaaagcatt agacgtccaa
    14281 gaggctgcag caaatgtacc aatcgaacga ttacttgtgg aaacagatgc cccttatctg
    14341 gcaccagttc cttttagagg aaagcgaaat gaaccaggct atactcgtta tacagtagaa
    14401 aagattgctg aacttcggaa tcttccgaca gaagaagtgg ctgcccaaac atggacaaat
    14461 gcgcaccgat tatttggtct aagcgaacat ggataagatg aagatccaag agattatagt
    14521 cgttgaagga aaagacgata caagaaggct gcgggaagta gttgatgcag atacgataga
    14581 aacaataggg tctgcaatca atgaagagat cctgatgcaa attgaacatg cccaagagac
    14641 tcgtggagtg atcgttttta ccgatcctga tttttcagga gaaaaaataa gaaaaatcat
    14701 tatggaagct gttcctcagg caaaacatgc ttttttgccg cgcacacaag ctaaaccaaa
    14761 gaaaaaggga agccttggtg tcgagcatgc aagtgatgct gctattttag aagcattgaa
    14821 aaaggtcgtg acgccagaca tttcccaaac ggctgtttct gaaatcacta gacaagacct
    14881 tttagactat ggtttaatag ctggggcaca agcaaaagaa aaacgagaaa aactaggtga
    14941 cgagttgcgc atcggttaca cgaacggcaa acaattggaa aaacgtttga agatgtttcg
    15001 tattacgccg aaagaactcg cccaagcaat gaaaatagtg gaggaacaac atgagtgaat
    15061 atcgtgaaat tgcgacaccc tctagaacaa aagagatttt attgaaacat ggtttttcat
    15121 ttaaaaaaag tttaggacaa aattttctga ctgaaccaaa tattttaagg aaaatcgtag
    15181 aaactgcgca aatagatgaa catacgaacg tgatcgaagt tggaccagga atcggtgcat
    15241 tgacggaaca attagccaag catgcaaaac aagtcgtagc atttgagatc gatgatcgtt
    15301 tgatccctgt attggctgat acgatgcaac cctatgacaa tgtgactatt gtacatcaag
    15361 atattttaaa gaccgatttg tcaacagctg ttagagaaac atttcatgag gagcttccgt
    15421 taaaagtcgt agcgaattta ccttactata ttacgacacc gatcatgatg cattttcttg
    15481 aatcagattt ggttgtggat gaactagtcg tcatgatgca aaaagaagta gctgatcgta
    15541 tctctgctga accaggaacg aaagcttatg gttcattatc gattgctgtt caatattata
    15601 tggaagccag tttagcattc atcgtaccaa aaacagtatt tgtccctcag ccaaatgtag
    15661 attcagcgat tttgaaactg acaagaagag atataccggc agtcgaagtg acagacgaaa
    15721 aagcattttt ccgattgaca aaagcggcat ttcagcaaag aagaaaaacg ctttggaata
    15781 acttgcagca ttcgtatggc aaagatgacc agacaaaagc atggttagca aaaagcttgg
    15841 aaacagctgg aatcgatcca aaacgtcgtg gggagacttt gtcattacaa gaattcgccg
    15901 cattaagcaa tgcgatgtca gaaaatatgc agtaaaaaaa gaggttgtga cagaagttgt
    15961 gaaaaagctg tcctgcatca agtaataaga acagccaaac aaaaatagtt cctcatgttt
    16021 ttcgtttgtt tgggcttatt accgcagatg caagcttttg aacaccgttt aagaaagagg
    16081 ttgtgggcct gccgtttaac tctaagtcac aaggaacaat ttcaaaaaac agcttctcat
    16141 gtttttgagt tagttggtct tattacttga tgcaagcttt tgaccactat tatgccgaac
    16201 aaggagatgt gacacaaatt ttgtcacatc tcctattttt gtttcttgat caaaaaattc
    16261 ttatacttga tactcacact cattttgtat ggatttagaa aagaatatgt gtcttgacag
    16321 ttattagtaa gtgagttata ctaagtcgac atttatgtgt caagacatat taggagagag
    16381 aaaaaatgag aaaaaattca gttcgaaaac taacgatttc tgctttattg attgggatgg
    16441 gggtcattat cccaatggtc atgcctaaaa tcatgattcc accagcttcc tttactttgg
    16501 cgtctcatgt gccattattt attgcgatgt tttttacacc aggagttgca gtggctgttg
    16561 cgctaggtac gacatttggt ttctttttaa caacgccggt tatcatcgca ttgcgagcat
    16621 tgtcacatct tgtgtttgcg ttgattgggg cttggtactt gcaaaagcat ccgagtatcg
    16681 ttttaaaaaa tggacagttt acttttgcta attggcgttt ccaagggttc aattttgtga
    16741 tcggtgtgat tcattcttta gcagaaatgc tagtagtcag catcttttac tttattggta
    16801 atatgcctga aacatattat tctcaaggat atttttatac agtattcatc ttgatgggga
    16861 ttggtgggct tatccacagt ttagttgatt ataatattgc ttattttata gcaggaacac
    16921 tcagcaaata ttttgatatc cccgtattta cggcagcaaa aaaagaaaat cggaaagagt
    16981 cgattcaagg gtacgcgaag aaaacgacat attagacatg atctctcaaa aaaaaaactc
    17041 tcatctagta atggataata aatcctctaa gatgagagtt ttttgtccta aaaagagctg
    17101 caccaacatc ttctggcaca gctctaacag ggggcaattt atggaagttt gatgacttgt
    17161 tctgtttctt tatcaaagaa gtggcctttg ctgatgttga aggcaaggtc gactatttcg
    17221 cctggtttat ggaaatctct tgcatctact tttgagatga actcagtaga accagttttt
    17281 gtgtaaagca tcgtttcagc tccaagtaat tcggaaacga caacttctga tttcactacg
    17341 gcttcaggtg aagcttcaag ggctacttgt tcactgtgga tgtcttctgg acgaataccg
    17401 aagataactt cttttccttc ataacctttt tcaactaata ctttgttttt tccttcagga
    17461 atacgaagct taagcccatg tccatctgtg ataacaccat ttttcaatgt cacattaaag
    17521 aagttcatgg caggagatcc aataaagccg gcaacgaaca tattgacggg tgtatcataa
    17581 acttctttcg gtgtaccgat ttgttggata aatccgtctt tcatgataac gattcggtca
    17641 gccatagtca ttgcttctgt ctgatcgtga gtaacataga tggtcgttgt ttcaagacgc
    17701 tggtgaagtt tggcaatctc agcacgcatg gctacacgta atttagcatc taaatttgat
    17761 aatggctcat ccattaagaa gacttttgca tcccgaacga ttgcccgtcc caatgccaca
    17821 cgttggcgtt gtccaccaga taaagcagct ggttttcgtt tcaagtattc tgtcagacct
    17881 aagatctctg ctgcattgtc cacacgtttt ttgatgtctg ctttatcata tttacgtaat
    17941 ttcaagccaa aagccatatt atcaaaaaca gtcatatgag gatacaatgc gtagttttgg
    18001 aaaaccatgg caatatcacg gtctttaggt gccacgtcat tcatgacttt tccgccgata
    18061 tttagttctc cttcagagat atcttccagt cccgcgatca ttcgcaaagt agttgacttt
    18121 ccacaaccgg aaggaccaac aaaaacgata aattcacggt ctttgattga tagattaaaa
    18181 tcagttacag aataattttc tgcattgtca tattttttat atacgttttt cagagccatt
    18241 tctaccataa tacgttccac actttctttt ttagttttat taactattta aagtataaat
    18301 gaaagcgtta actaacttca atgtcatgtt gaacaagaat tttttctttt ttttgtcaat
    18361 gtgctagttt taagctttaa taaatatcca taagaaataa aaactgatac actggagtaa
    18421 ataagtatgt taacaatatc aaaaggagtg tctcttatga aaatcgcttt gatcgctcat
    18481 gaccgaaaaa aacctatgat ggtgaaatta gcaacagcgt ataaaacaat attggaaaaa
    18541 catgaacttt ttgctaccgg gacgactggg cagaggatca cggaagcaac cggcttgccg
    18601 atccatcggt ttaaatccgg accgttaggc ggggatcagc aaattggagc catgatttcg
    18661 gaggatcagt tagatttggt gatttttctt cgagacccgc tggctgcaca gccccatgaa
    18721 ccagatgtaa cagcacttat ccgtttatct gatgtctatg agattccgtt agctacgaat
    18781 atcggaacag ctgaggtgct actaagagga ctggaagccg gcttcctaga ttttcgaaga
    18841 atcgtccatg aaatagacaa gcatccactt tcattttgat ggataagcgt atggaaaaat
    18901 aacgtttaat gttcgcctat atgtagctat aaaagctaaa caaactgata atatgcgata
    18961 taatacgaac gtattggata atataaacaa taatattagt ttttcgtatt tgcagtaaat
    19021 gtgaaaatat gctatagttt ctgtgggaaa agatcccaaa aataatacag agtagaaaat
    19081 aaagcgttaa gtgctaagag gatgggatgt tgcctcttgg acgaaggacg taatgttcgc
    19141 ggttttattt tcgcattcgc tgcatgatac gatgtagcag ctcttaaagg agatgctaaa
    19201 aataaagaaa caccggttag acgcacgtat gattgctatt atgggcttat tgattgcatt
    19261 gatggtcact ttgtcccgac tggtagcaat cgagacccca tttattaaaa tcagtgtcac
    19321 atttattcca caagtgatca tgggcattct ttttggtcct ttttggtcag ggataggcgc
    19381 agttttagct gatttagtag gaatggccct cttctcgaaa tctgcattct ttattggatt
    19441 tacattgaat gcatttattg aaggagcaat ctacggattc tttttctatc gaaaagagat
    19501 cacttggaaa aatgccattc tggctacgct tagtgtcacg ctgatcatca acttattttt
    19561 gacaccatta tggcttgcgt tgatgtacca tgtgccattg ttcagctggg tcgtttgggc
    19621 gccccgcctg ttaaaaacag taatatggtt accgattcaa tcaattgcca tttattacgt
    19681 aggacgtagt attccttaca aaaaaatttt aagaagttta gcgatccacg ctaaataaaa
    19741 aacaagcagt cttcccatcc cagaagactg cttgttttta ttgtgctgtg aattgtgctt
    19801 gatagagccg tcggtaataa ccatcttttt gaagcagctc atcatgggtg cccatttcga
    19861 caatagctcc ctgatccatc actaatatct ggtccgcatt tttgattgtg gacaggcgat
    19921 gggcaatcac aaaactggtt tttccttcca tcattgctaa gaaggcttgt tggatttttt
    19981 tctctgtcaa tgtatcgact gagctggtag cttcatctaa gatcaacata gggggattac
    20041 tgatcatcgt tcgagcaatc gtcaacagtt ggcgttgtcc atctgatatc tttaaccctt
    20101 gaccgccaat cttagtatct aatttttccg gcaaacgttc tacaaattca tacatataag
    20161 aggcttttag ggcatcattg atttctgcgt cacttgcttc cggattccca aaacgaagat
    20221 tttctcgcaa tgtactgtca aatagccaag tatcttgtaa caccattcca aaacttttac
    20281 gtaatgtatc acgttggata gagcggatgt catggtcatc gactgtaatt gttccttttg
    20341 ttgtgtcata aaaacgcatc agcaaattaa caagtgtgga ttttccggcc cctgtttttc
    20401 ctactatagc aatggtttga cctggataag cagtaaaatt gaaatcttcg atcaaacgct
    20461 gcttggggtc ataagaaaaa gaaacatgat caaaagagac ttttcctttg atatttttgg
    20521 gttccaaggc ataggcatct ggcaaatcag gcttttcttc tggctgatcg atcaaatcaa
    20581 atgctcgttc tagaccagaa aaagcggttt gcagttgtgt cgtgattcca gaaagttcga
    20641 taaatggttt agaaaactga cttgagtaga tcgtaaagct ggaaatcaca ccaacagtga
    20701 ttgacgaacc actcttcaat gccaataggc cgccaactaa accaatcgat aaataagcaa
    20761 ggtgatctac aaaacgagaa gacgggtttg tcaaggaaga agaaaattgt gcccgttgtc
    20821 ctttttcata tagatcagca tttagcagtt caaattgctg ttgactagct tcttcttgct
    20881 gaaaagcttt cacgattttc tggttaccga ttcgttcggt cacaaagccc gagatatccc
    20941 caataatcct ttgctgtcta tcgaaatttg tttgtgaagc acgagcaacg atccaactca
    21001 caaggaaaat aattggtgta gaacaaagaa cgaccaatgt cagaagtgga cttagacgca
    21061 tcataaaaat aaacgaaaga atgatgattg ccactccaga aaataattga ttgaaggccg
    21121 cagaaattgc aatggaaata ttgtccatat catttgtaaa tcgactgacg atatttccgt
    21181 gggagttttg atcataataa cgaagtggca atcgattcag atgagcaaat gcatcttttc
    21241 ttaattttgc aacggataag taagctaacc gattgcttaa cacttggatg agccattgac
    21301 tgactacgtt gattaaaacg ataccaccga atagaataag taaatggaac agtcgattga
    21361 agcggacctg tccttctcca atcatttgat cgatactttg accaatttgt aacgtcatca
    21421 caactgttgc aatcccattg atgattccta gtatcacagc tagccaaatg tcttttgcat
    21481 aggcagtaag gtaaggaatg aatcggcgga gcgtctgcaa ggataatttt tttactttca
    21541 taactattct tcctcctgtg atgcgacgat ttcctgatat tctgctgatt gagcaagtaa
    21601 ttcttcatgg gtaccctgag cagcaatctt accttgatcc atcactaaga tatgatgtgc
    21661 ttcttgaata gagcggacac gttgggagat aataatcact gtactgccaa gataagtctg
    21721 tagcgcctta cgcaaatcca agtctgtttg ataatccaac gcacttaaag agtcatctaa
    21781 aatcagtaat gctggcttgg caatcaaagc tcttgcaatc gtcagtcgct gtttttgtcc
    21841 gccagagaaa tttttcccat tttccatgac ttttgtatct aaaccatttg gaagctgacg
    21901 gacaaattct tctgcctgag cgattttcag agcttcccaa cattcttttt ctgtggcgtc
    21961 tttcttaccc cattgaaggt tttcacgaat agtcccggta aatagtacag aagtttgggg
    22021 aacaagagca atttgctgac ggagatgatc cagctgccaa gaacgaacat ccattccgtc
    22081 cattataact gtaccggaac tgacatcata gaaacgcgga atcaattgtg tcaaagtcgt
    22141 tttcccgctt ccggttggac caatgattcc aaggactgta tttcgcttca gctgaaatgt
    22201 aatattttgg agagaaagac cagaatcagg agtataacgg aagtcaacat ggtcaaaagc
    22261 gataattgct tcagaagaaa aatcgggagt agtactgacc tcagcttcaa gaatcgaatt
    22321 ttctgtgtct agcacctctt tcacccgatt tcctgaagct tcggcacgtg tgaagatcac
    22381 gacgaggttt gaaacaacga tcagtgccaa aagcatttga ttcatataat tgatcaaagc
    22441 aagaacttgt ccttgttgca agctaccaat atttactttg atcccgccaa ctgtcagcaa
    22501 acagatgatc ccgacattca tgatcaaggt tgtagcaggt gataataggg cagagatatt
    22561 ggaaacacgt aaataattgt tcgctagatc atttgtgctt ttatcgaact tctctgtttc
    22621 tttttttgtc tgcgcaaatg cgcggatgac acgaacaccg ctaagattct gactaacgtg
    22681 ttcattgagc tgatctagtt tttcttgcac tttttggtag agaggaacgg tttttttgat
    22741 gataaaaaat aaaatgattg agaaaatagg caataatgct aagaaaaaca gacctacttc
    22801 ccagtcgatc acaaaagcca tgaccactga cccgatactt aaaaacggtg ctctgatcaa
    22861 taaacgaatg accattgcta aagctagctg aagctgattg atgtcgtttg tcattcgggt
    22921 gatcaaggta tctgttccaa aatgattcaa ctcgttgtga gagaaagtat tgattttttt
    22981 gattagctga ttacgtaact ctgtaccaaa tccttgtgaa gctactgaag catagtattg
    23041 gcaaatgata gcacaaatca gaccaatcac agacatagcg accatccata agcccatttc
    23101 aatgattttt cctcggtcat tcatttttag tccattatcg atcaaggaag ccatcattaa
    23161 aggcaggaca agttcgaaga cagcttcaag aaatttgaag aacgggccca aaatgatttg
    23221 cttacgatag tcttttgcat aacgtaataa ctgaatcata tgattcctcc tattatttat
    23281 ttgtccacaa ttgaaaaaac aagtactacc acattgtagc ttaggaaatt tagaatgaaa
    23341 agagaacaag ccttttcata aatgaaagtt ttattatgaa gaagctttag aaattgaata
    23401 gactattttt tttaaaaaaa
//
LOCUS       DADVXM010000039        23121 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.040, whole genome shotgun sequence.
ACCESSION   DADVXM010000039 DADVXM010000000
VERSION     DADVXM010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23121
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.040"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            31..513
                     /locus_tag="KB927_001579"
     CDS             31..513
                     /locus_tag="KB927_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840500.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     LVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            710..1600
                     /locus_tag="KB927_001580"
     CDS             710..1600
                     /locus_tag="KB927_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBB6840501.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            1926..4400
                     /locus_tag="KB927_001581"
     CDS             1926..4400
                     /locus_tag="KB927_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6840502.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLLKRRNNTVAMTGDGVNDI
                     LAMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLV
                     KNIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNV
                     MEKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKF
                     RSQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLF
                     ERKNEKEQKPFSRVVKKFLSIFKREN"
     gene            complement(4503..6239)
                     /locus_tag="KB927_001582"
     CDS             complement(4503..6239)
                     /locus_tag="KB927_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBB6840503.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNGDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRAYTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLHGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(6236..6940)
                     /locus_tag="KB927_001583"
     CDS             complement(6236..6940)
                     /locus_tag="KB927_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6840504.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            7071..7574
                     /locus_tag="KB927_001584"
     CDS             7071..7574
                     /locus_tag="KB927_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBB6840505.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            7534..7872
                     /locus_tag="KB927_001585"
     CDS             7534..7872
                     /locus_tag="KB927_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBB6840506.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            7893..9311
                     /gene="ffh"
                     /locus_tag="KB927_001586"
     CDS             7893..9311
                     /gene="ffh"
                     /locus_tag="KB927_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBB6840507.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            9423..10001
                     /locus_tag="KB927_001587"
     CDS             9423..10001
                     /locus_tag="KB927_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBB6840508.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            10005..10526
                     /locus_tag="KB927_001588"
     CDS             10005..10526
                     /locus_tag="KB927_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6840509.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(10605..11159)
                     /locus_tag="KB927_001589"
     CDS             complement(10605..11159)
                     /locus_tag="KB927_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBB6840510.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            11412..11687
                     /gene="rpsP"
                     /locus_tag="KB927_001590"
     CDS             11412..11687
                     /gene="rpsP"
                     /locus_tag="KB927_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBB6840511.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            11699..11950
                     /locus_tag="KB927_001591"
     CDS             11699..11950
                     /locus_tag="KB927_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBB6840512.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            12074..12865
                     /locus_tag="KB927_001592"
     CDS             12074..12865
                     /locus_tag="KB927_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840513.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTATTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            13035..13556
                     /gene="rimM"
                     /locus_tag="KB927_001593"
     CDS             13035..13556
                     /gene="rimM"
                     /locus_tag="KB927_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBB6840514.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            13546..14307
                     /gene="trmD"
                     /locus_tag="KB927_001594"
     CDS             13546..14307
                     /gene="trmD"
                     /locus_tag="KB927_001594"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBB6840515.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            14443..14790
                     /gene="rplS"
                     /locus_tag="KB927_001595"
     CDS             14443..14790
                     /gene="rplS"
                     /locus_tag="KB927_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBB6840516.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            15100..15342
                     /locus_tag="KB927_001596"
     CDS             15100..15342
                     /locus_tag="KB927_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBB6840517.1"
                     /translation="MNDGKVKQVPSSTKKKNILLKEVLKRFDHGVTYTETEVNSILLN
                     VFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            15693..15947
                     /locus_tag="KB927_001597"
     CDS             15693..15947
                     /locus_tag="KB927_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HBB6840518.1"
                     /translation="MLELSKQLPVSDPRHFDYEEIAIKILEELQKNYTTKRVNGSNGL
                     LLHAVYDKNSLKGVDECVIWGDYFYVEGITRLAKTWYCYW"
     gene            15976..17235
                     /locus_tag="KB927_001598"
     CDS             15976..17235
                     /locus_tag="KB927_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBB6840519.1"
                     /translation="MKRWKKMMIGSIVLGMSLVFGACGNQEDSSEESANEITVSTWNY
                     ETTPEFKALFEAFEKKTGIKVKAVDIASDDYDTKLTTMLSSGDTTDVLTMKNLLSYSN
                     YALRDQLVDQTERIRELDTDAAEETYEMYDIDGKTYALPYRTDFWVLYYNKKMFDDAG
                     IEYPKNLTWDEYEDLAKKLSKNDGQVYGAYQHIWRSTIQAIAAAQNEANLVEPDYQYM
                     TDYYDRALRMQKEGAQMDFGTAKSTKVTYQSQFEEQKAAMMYMGTWYMAGILANKEAS
                     KTEVEWGITAIPQKKKGESVTTFGSPTAFAVNKNSKKQKAAQEFIEFAASEEGAKVLA
                     GVGVVPSYRTDEIDQLYFNLAGMPTDEISKKAFSPDEIKLEFPIDTYGPAIDKILQEE
                     YDLVLVGDETPEKGTVNMEKRVAAEKE"
     gene            17288..18184
                     /locus_tag="KB927_001599"
     CDS             17288..18184
                     /locus_tag="KB927_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6840520.1"
                     /translation="MENSINKKATNHLRRKRTWIAYSFIAPNFIGFFVFTLIPILFSL
                     VLAFMKWDSFSTPEFAGLDNFRKMANDETFWISLKNTFLYTAAVVPGTLVCSLGLALL
                     LNQKIRGMKLFRTIFFFPYVTSLVAIAVVWNMLFHPTVGPINIFLRRFIEHPPGWTSS
                     SNWALWAIVIVSIWRGMGYYMILYLAGLQSIQKELYEASSLDGANRWKQFLNVTLPSL
                     RPTTFFVTIMLVINCFKVFDLVQVMTDGGPGRATNVLVYQIYNEAFKKFDFGYASAIS
                     LVLFVIVLGVTVVQFSWNKRRT"
     gene            18195..19064
                     /locus_tag="KB927_001600"
     CDS             18195..19064
                     /locus_tag="KB927_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6840521.1"
                     /translation="MEESVRNERKKAKIRSKNMPFIQWLGMILLIVLALLTIIPFLWM
                     VSASFKANNEVLTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT
                     SSFAVYGFSELNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQ
                     AFNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVN
                     TWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQK
                     YFVEGIASSGMKE"
     gene            19074..19749
                     /locus_tag="KB927_001601"
                     /pseudo
     CDS             19074..19749
                     /locus_tag="KB927_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            19955..21619
                     /gene="alsS"
                     /locus_tag="KB927_001602"
     CDS             19955..21619
                     /gene="alsS"
                     /locus_tag="KB927_001602"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBB6840522.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            21632..22342
                     /gene="budA"
                     /locus_tag="KB927_001603"
     CDS             21632..22342
                     /gene="budA"
                     /locus_tag="KB927_001603"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBB6840523.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            22472..22969
                     /locus_tag="KB927_001604"
     CDS             22472..22969
                     /locus_tag="KB927_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBB6840524.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
BASE COUNT         7611 a         3992 c         4827 g         6691 t
ORIGIN      
        1 tgagagaaaa agtagtttgg gggaacgtta atgagaagaa aagcagtaat cgatcggctt
       61 tatttatttt tttggttttt tcctatcgtt ttgctacctt ttacatgggt aaatgctgtt
      121 gtacaaggtg cggagatatt aggcctgatc caaggaagcg gattagtggt ttctaggaat
      181 tttccagctt tgactgtttt ctatttagtg ataagtgtag gtctcttatt accaaaatct
      241 ctgatcaatc actacaattg gcagctgctt tacttttctt gcttattagt atttacatct
      301 atgttttctt tgctgcctcg cttgattatc ggccctaatg gtttgagcga gagtggattg
      361 aaggattcag cttattcctc catgtatttc ttgacgatca aaccatggtt ctatttagta
      421 attgcctcat ttattcttgc aacatttttt tacttctgga cagaaatcag gataaaaagt
      481 gaacgatctg tatctataaa aaataactat tgatggtgga tcatcagtaa aaaagcatat
      541 gagctgcgta aaatgcatgt ttctcatatg ctttttttat tattatgtaa agaatgcgaa
      601 aaacgtttac atgattttta cataacttaa ctatattttt acagcaacca tacgagggat
      661 ttacagtcga ctgataaact ttagttgtaa ataagaaagg agcaataaaa tgaaaaaagt
      721 attgtttact ctaggtatga tgggaattct tttagccgga tgcggctcag gatcaggaaa
      781 tacagatggc tctgccacac aaaataattc aagtgactca aatgaacaag taaaaatcgt
      841 tgcggtaggt tcgacagcat tacagccgtt agtcgatgca gcacaagaaa gctttgtaca
      901 agaaaatcca aattatcaaa tctctgtaca aggaggagga agcggaactg gtttgagcca
      961 agtcgaagct ggagcagtta ctatcggaaa ctctgatgta tttgcagaag aaagagacgg
     1021 agttgatgct tcaaaattag tggatcataa agtagcagtg gtcgggatgg caccaatcgt
     1081 caataaagat acagatgtca aagatatcac caaacaggaa ttgattgata tctttacagg
     1141 aaaaatcact aactggaagg aagttggcgg gaaagatcaa aaaatcaacg tcgtgaaccg
     1201 tgcaaacggc agcggtaccc gcgcgacatt cgaaaaatgg ggactggatg gtgctacccc
     1261 tgtgcagtcc caagaacaag attcatcagg aacagttcgg cagctggtaa gtcaaacacc
     1321 aggagcaatc agctatttag ctttctcata tctcgatgat tccacacaag cactaagtat
     1381 cgacggtgta gaaccaaaag aagagaatgt agcagataac agctggggaa tctggtcata
     1441 tgaacatatg tacacgaacg gaaaaccttc ccctgaagtc caaaaattct tagactacat
     1501 gatgacagaa gaaatccaag aaggacctgt caaagaattg ggctatttac caatcacaat
     1561 gatggaagta gaacgtgatc acgaaggaaa tatcaaataa ctagcagata aacatgccac
     1621 ggtagtcgtt actattaagg aaaaatcaac tatgtttccc cacatataca tttttccttt
     1681 aattgtgaaa aatagttcct catattttgc cgttttttga gctaataccg agggtcagct
     1741 gattgaacac cgtttattcg aaaaaaagag ctacgacata gaactgtcgt agcttttttt
     1801 ttgctatatg acaggaatga aaggtgtttg caagcttaat gtgaggaaca ctttccatat
     1861 ctgttctata ctggatagga gaagtttgga aatatccaga aaacgaaatc aatcgaggta
     1921 gccacatgaa gaataaatgg ataaatcgaa gtaaaaaaaa gaaagtaaca caaagatcat
     1981 cagataaagt catccgtctt tttccatcgt ataaagaagg attaacggca gatcaagtca
     2041 aggaacgaat agaaaaaggt gcagcaaata attcagtcga tcccacattc aaaacaaatc
     2101 agcaaatcgt attggaaaac atatttacgt atttcaattt gatctttctt atcttagcca
     2161 ttttgctttg tttagtagaa tcctataaga acttgacttt tttaccagtt atcatagcca
     2221 atacaggaat cgccattttt caggaaattc gatccaaaaa gatcttggac gaactaaatg
     2281 ttttaaatac agcaaaagtc aatgtcatac gagacgggat agaacaaaca atagatatag
     2341 aagaccttgt aatagatgac attgttattt tagagactgg acatcaaatt ccagcagatg
     2401 cagaggtcgt ggaagggaaa ctgcaagtta atgaggcttt attgacaggc gaagcagatg
     2461 aaataaccaa agaaataggc gatccattaa tgtccggcag tttcattgtt tccggaaaag
     2521 cttacgcccg attagacaaa gttggagcag attcgtatat ttcccagctg acagtcaaag
     2581 ccaagacaat gggagaagga gaacagtcgg agatgattgc ttctcttaat caattgatca
     2641 aatggattgg gatcatcatt attcctatcg gtatcctgct tttttctcaa agttactttt
     2701 ttaatggaaa cacgatcaaa gaaagtgtcg ttgcaatgga agcagcattg atcggtatga
     2761 tacctgaagg actgtacttg ctgacgacga ttgcattagc attaagtgcg actaaactag
     2821 caaagcaaag agttctttta cacaatatga aaagcattga gacattggca agggtaaatg
     2881 tcctttgtgt agataaaaca ggaacgatca cagaaaataa aatgtctgtt caaaaagtga
     2941 tcgtctctaa aaaacaagaa ataatcagtc agtcagatca attggaagca tgcattgctg
     3001 actatgcaaa agcgatggca ggagacaatg caacaatgga agctgttaaa gcatatttta
     3061 caaaaaccac tgatcaatcc tatcaccatg ttattccttt ttcttctgtc caaaaattca
     3121 gcagtgtagc gttggcagac aaggtgtatg ttttaggagc gcccgaaatg gttttgcgcg
     3181 atcaattgcc ggaatatgcg gaagagtttg tttctttcgc tgaaaaaggc tatcgcgtgt
     3241 tggtctttgg tgtgtacgat gggattcttg aagaaccagt attgacagaa gcagtcacac
     3301 cattaggcta tattctgatt gctaatccta tcagaaaaga agcaagagcc acatttgatt
     3361 acttcaaaaa acagcaagta gccatcaaag tgatttctgg agataatccg ctcaccgtat
     3421 ccaatgtagc tgtccaagca gggatttcac atgctgatca gtacgttgat gcatctaaat
     3481 tatcagaaga agaatatgaa gcagctgtcg aaaaatatac agtttttgga cgcgtcaagc
     3541 cagaacaaaa gaaaatcttc gttcaattgc taaagcgtcg taacaataca gtagctatga
     3601 caggtgatgg cgtgaatgat attctagcca tgaaagaagc agactgcagt atagcgatgg
     3661 cttccggaaa tgaagccgcc atgcaggcct cacaagtggt cttacttgat tctgactttt
     3721 cacgcatgcc agaagttgtt gcagaaggac ggcgcgttgt gaacaatatt gagcgatcag
     3781 ccagcttgtt tttagtgaag aatattttct cctttttgct ctcactgttt tcagtgatct
     3841 ttgctctgac ctatccttta gaaccatcac aaatcacatt gattagtttg tttactatcg
     3901 gacttccatc tttcttgctt gctctagaag aaaacaaaaa gcgaatcaga gggaaattca
     3961 tcatgaatgt gatggaaaaa gctgtgccag gtggactaac agatatgatc gtagtcggtg
     4021 cgttggtgat ctgcggggtg actttgaatc taaataaaac agatgtttct acagcatcta
     4081 ccatgctttt gattgcagta gggttcctcg ttctctataa aatctgttca ccgctgaata
     4141 aattcagaag tcagatcatt cttttctgtg ctagcggtaa ctttttttcg gtcatctttt
     4201 tgcataagct gttttcaatc accggtatct cagctgtatc acttttgctg ttgagcattc
     4261 tatttttctc ggcagattcg atttttaggc atttgaccac attggtagaa tatttgtttg
     4321 aacgtaaaaa tgaaaaagag caaaagccgt ttagtcgcgt agttaaaaaa tttctatcga
     4381 tatttaaacg agaaaattga cgaaaagtat ctcaaaaaag agtaaaaaag aacaaccact
     4441 cgtgtatctt tcgaagcagg atgagtcatc caactttaaa acgcacgagc agttgctctt
     4501 ttttacattt tcggaatggt aacggtgaaa gtcgaacctg ttccaagatg actgtctaca
     4561 gtaatcgtac catgaaggag ttgcacgtag tcttttacaa tcgctaaccc taatccggtc
     4621 ccgcctgaat gccggcttcg cgccttgtct acgcggtaaa aacgctcaaa gatccgttcc
     4681 tgatcctcaa tgtcgatacc tataccaaag tcttggacag aaaacgatag atcatctgtt
     4741 gcctgatagc ggataataat ctcgctgtcg ctttttgaat attggacagc attttcaatc
     4801 agatttttga taattggata aaggatatct gttttagtag taaatggttc gttctttcca
     4861 atcaatcgaa tcgtcaaccg tttcttttcg atgattggct gataattttg aacgatttgc
     4921 tggaaataag gttctgtata aattgtctgg atctcgtaag aattctcgcc atcttttgac
     4981 agctggatga tttcccgaat cagtttatct aaccggatcg catctttttg catgatctca
     5041 agaaaagaag tcagagtttg cgggtcatct tttgcaccat ccagtaaagt ctcggtaaaa
     5101 ccaatcagtg aagtcacagg agtttttaat tcgtgagaga cgttgccaac gaaatccttt
     5161 tgtagctttt ctaaacgtcg cactttcgtt aagtcatacg ccacccctag aatctgtccg
     5221 gtaccttctg aattagtaaa gtagcgcaaa ctcaagtcta atgtctgccg accttctgta
     5281 agggtgatct cctgatggat cagcggatgc tcaggagtca cttgatgaat cagctgaatg
     5341 agttttggct cttgaatgac ttctgtgtac cgctgttcag gttgatagct taccacgttt
     5401 aaatgtagct gcatctttgg attaagcagt agtaaacgag aatcagcatc atcaatcagg
     5461 aatacgccaa tcatcagttc gttcagtaac gtatataatt gctcttctgt ggtagtatac
     5521 gcccgataca tcttactcat ttgttcgctc aacgcattga tcgtctgata caattcttcc
     5581 cattgatcgg gtgtttgcat gattacttcc gcctgattag gattttgcac catttttttt
     5641 agtacgggca gcacggtttt caatggctgg tttttttgat agatcagata atagatcatt
     5701 cctgcaagaa caaggaagaa agacagaaag aagaaaaaga cccaacggcg aaaactctca
     5761 gttctcggta aaaaaccgct tgtcggttct gcgatacgta aaatggcttc taactggcca
     5821 ctttttttga ctggtaatgc gacatataaa agatccccat tcaaagtagt acttttgcgc
     5881 aaagcgctac ctaggttccc accattcaat acggctttga tttcgggacg ggagtttcgc
     5941 tgttcattca atgtttcatt gtttgtgtca aataagatct ttccagtagc atccattaaa
     6001 gtaatccgtt cgttcgactg atggacgaat tcttccaaag cagttttgtt ttgcgctgct
     6061 tggaggtttt cgacatctaa ttgccggatc agcagttgtg ctttttttgt caggtagctt
     6121 tcttgctgtt ccacgatctg ctgttgaaaa taatgggaaa tcaattgcca gccaccaaaa
     6181 aacaaactaa ctaaaagaat aagaaagaag agacgttcat aaattttttt ccatttcatc
     6241 gtttgggttc ctgaaactta tagccaaatc ctctaatagt caccaagtac tttgggtgtt
     6301 ttggatctcg ctcgattttt tctcgcaaat gactaacgtg tacatctacg attcggcttt
     6361 gtcctgcgaa gtcaaaattc caaatgcggt ctagcaatgt gtctcggtcg atcacacggt
     6421 cttttcgttt catgaaataa acaagtaatt caaattcttt cggtgttagt tcaatcagat
     6481 ggtcgtctac ggtcacttga taattggtca aatcagcagt gatttgtcca atcgatagat
     6541 attcaggctc agcttcatct tttgattgct tacgaggttc aattcgtctg aatattgctt
     6601 tcatacgggc taatacttcg cgaggactaa atggtttggt caaatagtcg tcagcaccta
     6661 tttctaggcc aatgatccga tccacttggt catctttagc cgtcagcatc aaaatcggtg
     6721 tttcattttt ttcttgacgc agccgctgag tgatctccat gccatccatc gttggaagca
     6781 tcacatctaa aatgatgaaa tcaaatgatt gttctaatgc taattctaat ccttcgcctc
     6841 catctgtggc actggttacc ttgtagcctt ctttttccaa attgaacgtc aagagcgtta
     6901 caatagaagg ttcatcatca acaactagta tttttttcat tcaaatctcc tttaaatagg
     6961 tttcattctg tttatatttt agcatagaat cagtacaaag ggctatttta caaaagaaat
     7021 aaatggtata ataggaaggc actttgctga atagaaagga agagcagtca atgattggaa
     7081 tcagtgcatg tttaggcggt ctggcctgtc gctatgatgg acagaaaaaa gaagtaccag
     7141 aattgatgga actagttgaa actggagaag ctgtcatggt ctgtccagaa gtgatcggcg
     7201 gattaccaat tcctagagat cccgctgaaa tcattggtgg aaatggattc gatgtgtgga
     7261 aagatcaagc aaaagtatgg acgacaagcg gcgaagatgt aacggaagcg tacaaaaatg
     7321 gcgcgatcaa agcctatcaa aaattgcagg aaaaacacat tgatctagtc atcatgaagg
     7381 aaaaaagccc ttcatgcgga acccattcga tttatgacgg gagtttttcc ggaataaaaa
     7441 aaaatggtgc cggagtggct actgcttatt ttattcagca aaaaatgact gtgctctctg
     7501 atgaagaatg gctgaaaact agaggtgagc agaatggaaa tcgaaaagac caatcgaatg
     7561 aacgcgctct ttgaatttta ttcgacctta ttgacagaaa aacaaatgaa ctacatggaa
     7621 ttatattatg cagatgattt ttcattaggt gagatcgcgg aagaatacga agtaagccga
     7681 caagcagtat atgacaatat caagcggaca agcaagatct tggaggatta tgaaaaaaaa
     7741 cttcatcttt tttctaatta tattgttcga gaacaggtat tggaaaatat gactgcatat
     7801 attacagata agtacccgga agataaaaaa ctacttgaat atgtacagca aattcaagca
     7861 atcgaagaat aaataaaagg aatgaagaaa atatggcatt tgaaagctta actgaacgtc
     7921 tccagcaggc gatgggaaaa ataagaaaaa aaggaaaagt atcagaagct gacgtaaaag
     7981 aaatgatgcg ggaaatccgc cttgccttac tagaagccga tgttaacttg caagtagtca
     8041 aagattttac taagcgcgta cgcgaacgtg cggtaggggc agaagtgctg gaaagtttat
     8101 cacctgcaca acaaatcgta aaaatcgttg atgaagaatt gacgatcaca cttggttctg
     8161 aaacagcaga gttaaataaa tcaccaaaaa taccaactgt tatcatgatg gctggtcttc
     8221 aaggggcagg taaaacgacc tttactggta aattagccaa ttatttaaag aaaaatgaaa
     8281 atgctcgtcc gctcctaatc gcaggggacg tatatcgacc agctgcgatc gaccaattga
     8341 aagtattagg tcaacagcta gacgttcctg tatttgatat gggaactgaa gtcagcccgg
     8401 tagagatcgt ccgtcaaggg atggagttag caaaagaaaa gaaaaacgac tatgtattga
     8461 tcgatacggc aggacgtctg catatcgatg aaacattgat ggatgagttg aaacaaatca
     8521 aagaattgac gcaaccaaat gagattttgc ttgttgtcga tgccatgact ggtcaagatg
     8581 ccgtcaacgt agctgatagc ttcaaccagc aattaggtat tacaggggtc gtcatcacta
     8641 aacttgatgg ggatactcga ggcggggcag cactatcgat ccgctcagtg acaggcgcac
     8701 caatcaaatt catcggttct ggtgaaaaat tgactgactt agaagtattc cacccagatc
     8761 gtatggctag ccgtatcctt ggtatggggg atatgctgac attgattgaa aaagcgcagc
     8821 aagactatga cgagaaaaaa gcggaagaac ttgcacagaa aatgcgggaa aattcattcg
     8881 atttcaatga ctttattgaa cagcttgatc aagtgatggg tatgggccca ctggaagatc
     8941 taatcaaaat gatcccagga atgaatcaag tccctggaat cgaaaacgtc aaggtagatc
     9001 caaaagatgt tgaacgcaaa aaagcgatgg tttattctat gacgccagca gaaagagcaa
     9061 atcctgatct gttgaaccca agccgtcgtc gccgaattgc tgccggttct ggaaacagtg
     9121 ttgttgaagt gaatcgaatg atcaaacaat tcaaggaatc aagaaaaatg atgcagcaaa
     9181 tgtccaaagg ggatatgaac atcccaggta tggaccaaat gtttggttca ggcgtcaaag
     9241 gaaaactagg caaaatggcg atgaatcgaa tgatcaagaa aaataagaag aaaaagaaaa
     9301 aacggaaata agatgaaaaa aacagcttcg gtacagactg aaaatgtcta ctgccggagc
     9361 ttttctatca gcaattttta ttctttacta atacaattac tctaaacgaa gaggtggcac
     9421 agatgagatg tccgtggagt gaacaaacag aaagtatgcg gcaatatcat gatactgtct
     9481 ggggtgttcc tgaatatgat gaccaaaagc tgttccgaaa attgatgctt gatattaatc
     9541 aagccggatt gagctggcag acgattttaa ataaaagtga agcattcgat gaagcatatg
     9601 atcgattcga tattaaaaaa gtcgcaaatt atggagaaac aaaaatcagt gaactaatgg
     9661 aaaacaaagg aattattcgt aaccgaagaa aaatcgaagc agccgtccaa aacgccaaag
     9721 cagtcttgaa aattcaagaa gaaatcggca gtttttcaga gtatctttgg tcgttttcta
     9781 atggaaaaat cgttgattct tcttatcatt cacaagaaga agtcccaaca acaagtcctc
     9841 tttcagatga attagcaaaa gatctaaaga aaagaggatt taaatttatc ggaagcacaa
     9901 caatctatgc ttttttagaa gctgtcggga tcatcaatga tcaccttgac agttgtttcc
     9961 gcaaagaaga ggtcgtacgt atcggcagaa agggcgaata aagcatgcga aaaatcatat
    10021 tttatggtgc tataagttta gatggctatt tggcaacgaa aacggatgat cttcaatggc
    10081 tttttgacac tccaacaggt aagcaaacca cttatgaagc tttttatgaa acaatcgata
    10141 cgaccatcat gggcagaaaa acttatcagg aagcaaaaaa atatttggag accgaagcaa
    10201 tttatccaga gaaaaagaat ttcgtttttt ccacccacgc acaattacaa ttgccagatg
    10261 ctgaggtcgt aaacgaagat cctgttgctt ttctaaaaaa tctacaaatg acagaaggaa
    10321 aagatatctg ggttgtgggt ggcggtcgat tgatcaaacc gctattggaa catcaaatga
    10381 ttgatgaatg gtatatccag attacccctg tattattagg ggacgggatt cctttattcc
    10441 aaaaaggaac atatgaagcg cgttttgaaa tgctagacac gacacgattc ggtgaattta
    10501 tcgaattgca ttatgtacga aagtagaagt aaataaaata aaaaaggcaa ctatatgcag
    10561 aaatgtcctg tacatagttg ccttttttat taccgttatg ctttttactc tgttaatttg
    10621 ttagaaaaat ctagatacgc atctaaaatc gtttggaaga aacttaatgt tccttcaacg
    10681 atattaccat tttcatcaat tagattcgca acgtttccga tatatgcttc cggttgctgc
    10741 aaggttggca cattcaaaaa gacaagtgat tgtcgtagat ggtggtttgc gccaaagccg
    10801 ccgatcccac ctggtgatgc agtaacgact aaacctggtt tatgatccca aacactgtgt
    10861 ccataaggtc ttgagcctac atctaaagca tttttcaata ctgctggcac agaacggttg
    10921 tattcaggag taacgaaaac gacaccgtct agtcccctca cttcctcacg aaaacgagtc
    10981 cattcagcag gagcctgttc tggagtttcg agatcctcat tgtaaaatgg cagatcatcg
    11041 atttttacaa atacactttc gtacccttca ggaagcaatt tcgcaaaagc ttctgctact
    11101 tttttgttgt aagaatcttt tcttaaacta ccaataaaaa atccaatttt ttttgtcata
    11161 cgatttttcc tccttcaaac tatctataac aatcttacaa aaaataagta actggagcaa
    11221 ataaaaacac ttactgacaa aagctacata gaagatagat tacttatttt taacaaaaaa
    11281 gaagtctaaa atcttctatt tcctaaaaaa aatcgaattt aatcaagctg taaagaaaaa
    11341 aagctttaca gggtaaaaaa aaactgttac actacatctt gtgaataaaa caatggaggt
    11401 ggaaataaat aatggcagtt aaaatccgtt taaaacgtat gggttctaaa aagagtccgt
    11461 tttaccgtat cgtcgtagct gattcacgtt ctcctcgtga tggacgtttc atcgaaactg
    11521 taggtactta caatcctttg aaagaccctg cagaagtagt tttaaaagaa gacttagttc
    11581 ttgactggtt atcaaaaggt gcacaacctt ctgacactgt acgtaacatc ctttcaaaag
    11641 aaggcgttat gcaaaaacac cacgaagcta aattctcaaa gaaataaggt gaccggatat
    11701 gaaagattta agcgacttag tcttaacaat cgttcgtccg ctagtcactt atcctgatca
    11761 agtcaagtta gacgtcgtag agtcgaaaga cttttacgag tacaatctaa cagtggctcc
    11821 tgaagatatt ggccgtatca ttggaaaaca agggcgtgtt gctaaagcaa tccgcacaat
    11881 cgtttacggt gttcggatca atgcaccgaa aaaagtgcgt ttgaatatca tcgatgataa
    11941 ggaaaagtaa ataaacgtgc tgtactcgaa ttttcgagtg cagctttttt gtttttttat
    12001 taattgaaga aatgattatt tggcaaaaca agcaagaaag cgtatcctta taggaggagg
    12061 gagtgaacag ccaatgagaa agaaaatgtt atttattcca tttgctctat tgttaagcgc
    12121 ttgtagttcg gttactcaag aatcagacaa tacacatcta tcaagcagta tatctgaaac
    12181 tgttaccagt ccagaaaaaa gtagtaccaa aacggctacc accactgaac aaacaatggc
    12241 tacctcaaat aatgagaaaa agactgcttt agaccagttg aaagaacaac agccaaatgt
    12301 tcccatgcct ctagatgtac cagtctcttc aggctatctc aatatcgcag cgacacatac
    12361 aaagcaaggt tattctattt tatattacag aacagatcgt cccctcgggt tgaatgctga
    12421 cgaattgaat caagaaacgc ctattgcaac ctatctatat caatatgggt ttgcttctag
    12481 tcaagaaaca atccaagttt tgcagccctt tgagatcgac acaaatggtc agcaagtgga
    12541 cttaggttct cgaatcacag ggtatcagca aggtgcagca ggttcaagtt ttcttgaatg
    12601 gcaagaagga aactggcgta ttcgaatccg tgggaataat atagaaggcc aagatccctt
    12661 actattagct aaagaaatcg tagcttattt ggaagaaaac agtctaccag cacctgaaca
    12721 atttggtaaa attactgttg atatgggtga tacgacgaat cgagccgtag aagtaagctg
    12781 gcaagaaccg aaaaatgcct atacgatcac tcatcaagat cctatgtctg cgttgaagat
    12841 ggcagtttct atgaagaggt tgtgaaatca gcgcgctgat ctgagcccat catttaactc
    12901 caagtcacag gaagtaatca aaaatagcac gccgcatttt tgcataattt tggcttaata
    12961 ccttaaaaga aaactagaat tgcctcttca cacatgctaa aataaaacag acaaaaaaga
    13021 aatggggata taagttgact gaatacttga atgtaggaaa aatcgtaaac acacaaggta
    13081 tcaaaggcga agtccgtgtt atctcaacaa cggatttccc agaagaacgt tacaaaaaag
    13141 gaacggtgtt aacactattc caagacggaa aagcacctgt ggaattaaca gtcaaaagtc
    13201 atcgcaaaca taaaaatttt gacttattga gttttgaagg acatccttct atcaatgatg
    13261 tggaaaaata tcgggatggc atattaaaag tgtcaaaaga caactctgta gatctagctg
    13321 aaaatgaatt ctattaccat gagatcatcg gtctgcatgt attagaagat ggaactgagt
    13381 taggtaaagt aaaagaaatc ttgtcaccag gtgccaatga tgtttgggtc gttcaacgtc
    13441 cgaaaaaagc tgatatattg cttccatata tcgcttctgt cgtcaaagaa gtcgatttag
    13501 aagctggagt ggtccgtgta gaaattccag aaggactgat tgacgatgaa gattgatgta
    13561 ttgactttat ttccaagaat gtttgaaggt cctatggggg aatccatcat cggtaaggct
    13621 gtagataaag gattattaga tatcaatatc tctaacttcc gcgattattc agataacaaa
    13681 catcagacag tagatgatta tccatacggc ggtggagcag gtatgctgct caaagtccag
    13741 cccatctatg ataacatcca agccattgaa aaagctgcac cggatgtcaa aaaaagagta
    13801 attcttcttg acccagctgg taaacgattc gatcagaaaa tggcagaaga attttcacaa
    13861 gaagaacact tagtattcat ttgtggtcat tatgagggat atgatgaacg tatccgcaca
    13921 ttagtgacag atgaagtttc cttaggagat tatgtcctta ctgggggaga attaggtgcg
    13981 atggtcatga tcgatgcaac agttcggctt ttgccagatg tgttagggaa tcagacttca
    14041 gctcaaacgg attcttattc aaccggttta ttggaacatc cccaatatac tcgcccggca
    14101 gaatataaag ggatgaaagt accagaagta ttgacaaatg gaaatcataa attgattgaa
    14161 gaatggcaat taaaagaatc actaagaagg acctatcaac gtcggcctga tcttttggaa
    14221 acacttgaat ggacacctca aatgacgaaa tttttagaag aaatcaagaa agaagaacaa
    14281 gaaaaaacag cagatgaagc caagtgactt tttctaaaat attctttaca gtaggttgat
    14341 aatatgttag tattttatgg tgagtgcaaa agcacttaac tattacgata ttccgctatg
    14401 agaaaagctc ataagaatat ttggaataag gagaagaaaa ccatgaatcc attaatcgaa
    14461 gaattaacaa aagaacaatt acgttctgac atcccagcgt tccgccctgg tgacactgtg
    14521 cgtgttcacg caaaagttgt tgaaggtact cgtgaacgta tccagttatt tgaaggtgtt
    14581 gttatcaaac gccgcggtgc tggaatcagc gaaacttata cagtacgtaa agtttctaac
    14641 ggagtgggcg ttgaacgtac attcccattg catacaccac gtgttgcaaa aatcgaagta
    14701 gttcgctacg gtaaagtacg tcgtgcaaaa ttgtactacc tacgtgcatt acacggaaaa
    14761 gctgctcgta tcaaagaaat ccgtcgttaa tcattgttat cagactgaga aagaaccctt
    14821 ggtattcaag ggttcttttt tcttagcatg taatttgaac accctgatcc agtttttttc
    14881 tttaattatt ggtaggggag aataatggat tagaataaat ctacctataa gtagtagtaa
    14941 aaaaaagagc actatgataa tatctttctt aagagtaacc gctttaataa aaaatccaga
    15001 atattctaac ataaatggag tattcttaga atcaaaagga gaaagaagat ggtttatact
    15061 tatacggagc aagaaaaaat gaaagtttga gacacattca tgaatgatgg aaaagtaaaa
    15121 caagtaccaa gttcaacaaa aaagaaaaac atcctattga aagaagtctt gaaacgcttt
    15181 gaccatggag tgacttatac agaaacagag gttaattcga tactgctgaa cgtattttct
    15241 agtggcgatt atgtcgaaca aagacgttat ctaatcacat ttggcttttt caaaagaagt
    15301 tcagacggtc gggcatatca gatgatggga attgaaaatt agaagtttta atttatactc
    15361 attgaaaaaa gttcaagtat gcgatattgg ttctacaccg catacttgaa ctttttttgt
    15421 catctgtatc tataatacaa agccaagaac gttattcaaa atatggatag ctatgataaa
    15481 agctaatgag cgattcgcag ttaaataagc aatcgtcagt aaaatcgttc caggagcgta
    15541 catgaaaaaa tcaattggat gcgttacatg aataaagata attctctttt atttgtacga
    15601 ataaatacca aaacgtacct cctaaaatta gattcaaaga agatagcaaa gaggaaaaag
    15661 atagttctgc agcagctata gcggcatgtg gattgctaga actttccaaa caactgcctg
    15721 tttcagatcc tcgtcatttc gattacgaag agatagcaat caaaatcttg gaagaattac
    15781 agaaaaacta tacaacgaaa cgagttaacg gatcaaacgg tctgcttctc catgccgttt
    15841 atgataaaaa cagcttaaaa ggtgtagatg aatgtgtgat ctggggcgat tacttttatg
    15901 tagaaggaat cactcgtcta gctaaaacat ggtactgtta ctggtgatgt ataagagaag
    15961 aggaggattc atataatgaa gcgatggaaa aaaatgatga ttggatcaat agttttagga
    16021 atgtcactcg tatttggtgc ttgtggtaat caagaagaca gtagtgaaga atcagcaaat
    16081 gaaattaccg tttcgacatg gaattatgaa acaacacctg aattcaaagc gctctttgaa
    16141 gcattcgaaa agaaaacggg aatcaaagtg aaagcagtag atattgcttc agatgattat
    16201 gatacgaaac tcaccacgat gctttcttct ggagacacga cagatgtatt gacgatgaaa
    16261 aatcttttgt cgtattcaaa ttatgcttta cgagatcagt tagtcgatca aacagaacga
    16321 attagagaat tagacactga tgctgctgaa gaaacatatg aaatgtatga tatcgatgga
    16381 aaaacatatg cattgccata tcgaacggac ttttgggtac tatattacaa taagaaaatg
    16441 tttgatgatg caggaatcga atatccaaaa aatctaactt gggacgaata tgaagattta
    16501 gcaaaaaaac ttagtaaaaa tgacggacaa gtttacggag catatcaaca tatctggcgt
    16561 tcgacaatcc aagctattgc agctgctcaa aacgaggcga atcttgttga accagattat
    16621 caatatatga ctgattatta tgatcgagca ttgaggatgc aaaaagaagg cgcgcagatg
    16681 gattttggca cggctaaatc aacgaaagta acctatcagt ctcaatttga agaacaaaaa
    16741 gcagcaatga tgtacatggg aacttggtat atggctggca tactcgcaaa caaagaagca
    16801 agtaagacag aagtagaatg gggaattaca gctattcctc agaagaaaaa aggagaatcg
    16861 gtcacgacgt ttggctcacc aacagcattt gctgtcaata aaaactcaaa gaaacaaaaa
    16921 gcggcgcaag aatttattga atttgcagcc agtgaagaag gagcaaaagt attagcagga
    16981 gtaggagtag ttccttcata tcgtacggat gagattgatc agctttattt taatctcgct
    17041 ggaatgccaa cggatgaaat ttctaaaaaa gctttttctc ctgatgaaat caaacttgaa
    17101 tttccgattg atacgtatgg gcctgcaatc gataagattt tacaagaaga atatgactta
    17161 gttttggttg gagatgaaac gccggaaaaa ggaacggtaa atatggagaa acgtgtagct
    17221 gcggaaaaag aataatcatg aaaggagaga agccaagaga taaaacactc ttggtttcgt
    17281 catcgaaatg gagaatagta taaataagaa agctacaaat catttgcgta gaaaacgaac
    17341 gtggatcgct tattcgttta tcgccccgaa tttcattggt tttttcgttt ttacattaat
    17401 accaatcctg ttttcgcttg tactagcatt tatgaaatgg gattcttttt caacgccaga
    17461 atttgctgga ctagataact ttcgtaaaat ggccaacgat gagacatttt ggatttcttt
    17521 gaaaaatact tttttatata ccgctgctgt agtgcctggc acacttgttt gttcgttagg
    17581 gctagcttta ctactaaatc agaaaattag agggatgaag ctttttcgta cgatattttt
    17641 ctttccgtat gttacttcct tagtagcaat tgctgttgtt tggaatatgt tgtttcatcc
    17701 aacagtggga cctattaata tctttttaag acgatttatt gaacatcctc caggttggac
    17761 ttcaagttca aattgggcgc tttgggcaat tgtaattgtc agtatttggc gagggatggg
    17821 ttattacatg attctatacc ttgcaggact acaaagtatc caaaaagaac tatatgaagc
    17881 gtcttcgcta gatggagcaa accgttggaa acaatttttg aatgtgacat taccttcgtt
    17941 gagaccaaca accttctttg taacgatcat gcttgtcatc aattgtttca aggtgtttga
    18001 ccttgtgcaa gtgatgacgg atggcggccc tggtcgagcg acaaatgtgc tggtttacca
    18061 aatctacaat gaagcattca aaaaatttga ttttggttat gcttcagcta tttcacttgt
    18121 tttgttcgta attgttttgg gcgttacggt tgttcaattt tcttggaata agcgtcgtac
    18181 ttaggaggtg tgatatggaa gagagtgttc gaaatgaaag aaaaaaagca aaaattcgtt
    18241 caaaaaacat gccctttatt caatggttgg gtatgattct gctgattgta ttagctttat
    18301 tgacgatcat tcctttttta tggatggttt ctgcttcatt caaagcaaat aatgaagtgt
    18361 taacgattcc gattcaatgg atccctaaaa cttggcattt agagaattat ctggttattt
    18421 ggtctcgtat tcctttagtg acatttttta agaatacagc ttttttaagc gttgtgatca
    18481 cgttgattca gttgtttact tctagttttg ctgtttacgg gttttctgaa ctaaatttta
    18541 aagggcgcga tattttattt ttagcatata tcggcacgat tgctgtccct tggcagtctt
    18601 atatgatccc gcagttcatt atgatgagaa aagtgggttt aacagatacg ttgtggtcgt
    18661 tggtgctatt acaagcgttc aatgcttttg gtgtgttctt gttgaagcaa tattacagta
    18721 gtatcccaga ttctttatgt gagagtgcgc ggatcgatgg cttatcagag tgggaaatct
    18781 atcgcaagat cattttacct cttacaaaac cggcgattgc cagtttgacg atcatcacat
    18841 tcgttaatac atggaacgat tatatggggc cattcattta tttgtcttct acggaaaata
    18901 aaacaatcca gttagggttg aaaatgttta ttgggctatt tgatgcagag tacgcattaa
    18961 tcatggctgc ctcagttgtt tctgttcttc ctgttgcttt tatattttta gcgatgcaaa
    19021 aatattttgt agaagggatc gcttcatcag gaatgaagga ataggaggtg attatgaaag
    19081 agcagcgttt tgacaaaaat gtttatatgg aattctttta ttggttgtat caatcattgg
    19141 caagtagcct ttgtttttgg tgtgtcaata tcttgtatat agcagctgcg ttccttttgt
    19201 cgatagatgg aaggaatgtc ttttccttta ttttttcttt actttttatt ggtccaggtt
    19261 gcatcgtgat gataggtatg acagaagaat tagcaaaaga aaaaagtttt tcaccagtac
    19321 gtttgttcat aaagacgttt cgccaatttt ggctaaaggg atttttttat tggctatttg
    19381 cttggatagt tagtgtgata atgatttttg attgtttctt ttttatacgt ttttcttatg
    19441 gaaaatggtt gattccgttg tttgttttac ttgcttgttt tacttgcttg tttatcagtt
    19501 tcctttagca tcaactgctg gtattttcag gtgagaaatc cagcgtcgaa accaaatcaa
    19561 gttctacgga tagcgttcta ctatacgttg aaaaaatggt atgtgagttt actagatttt
    19621 ttactattga caagtttgtt tctcttcttt ttcgtaaagc cccaatggtg tattctacta
    19681 ggtccttcta tcgtatttgg tttgatttac ttcaacaatc gtaaattgat gagaactatg
    19741 gatctgtaga ctttataaat tgaaactttc aattaagaat gacagttttt tatgtaaaaa
    19801 ctgtcattct ttttcatttt ttgaaacata tggctaaaca aatgaaataa aacatgctat
    19861 acttttgaat gaaacaggtt tagaaactgt atcacttatt tgtgattatt tctaactaat
    19921 aattaaaaat aaagcataaa aaggacgatg ttcaatggct gaaaaaatga aacaaggttc
    19981 gaaatctgta gtagaaagtt tgattaatca tcatgttgat tatgtattcg gtataccagg
    20041 tgcaaaaatc gatggtgtat ttaatgaatt agaggatcaa ggtcctgaat taatcgtgac
    20101 tcgtcacgaa caaaatgctg catttatggc acaagcaatc ggacgtatta caggagagcc
    20161 aggagtagtt atcgcaacaa gtggtcctgg tgctagtaac ttagctacag gtttggtaac
    20221 agcgacagca gaaggtgacc cagttttagc aattgccgga caagtaaaac gaagcgatct
    20281 attgaagttg acccatcaaa gcatggataa tgcagcactg ttccagccaa tcacaaaata
    20341 cagtgcagaa atccaagatc cagaaacaat ttcagaagtg attgccaatg cttatcgtat
    20401 ggctaagagt tcaaaaaaag gcgcgagctt tatcagtatc ccgcaagatg tagtggatgc
    20461 acctgtccaa ggtaatgtca tcaagccatt gagcgatcct aaattaggtt ctgcttctgc
    20521 agatgatatc cgttacctag ctgaacgcat tagagaagca aaactaccgg tactattagt
    20581 aggtatgcga ggatcaagtg aaaaagaaac gttagccatc aggcaattag ttgaaaagac
    20641 agcattgcct gttgtagaga cattccaagc agctggagtg atctcacgtg aattagaagc
    20701 gcatttcttt ggtcgtgtgg gtttatttag aaaccaacca ggagatatgc ttttgaaacg
    20761 aagtgatcta gttattgcaa ttggctatga tccaatcgaa tatgaagcaa gaaactggaa
    20821 tgcggaaaaa gatgcgcgga tcattgtgat cgatgaagcg ccagctgaaa tcgatccttt
    20881 tatgcagcct gaaagagaat tgatcggtga tatctcagcc actcttgatt tattgacagg
    20941 ttcattagag cctcaacaag tgtcagaaga tgcaaaagaa tatttagcat ctcttcaagc
    21001 aaaattaacg gagcgggaca ttgttcaatc aaaaggagaa gcaggtatct tgcatccttt
    21061 agaagttatt aacacgcttc agtcaaaagt aacagatgat atgactgtta ccgtagatgt
    21121 aggtagtcat tatatttgga tggcacgcca ctttagaagt tatgaacctc gtcatttgtt
    21181 attcagtaat ggtatgcaaa cgcttggtgt tgcattgcca tgggcgattt ctgctgcatt
    21241 ggtgcgtcca aatacacaga tcgtatcagt ttccggcgat gggggatttt tattctctgc
    21301 ccaggattta gaaacggcgg tacgtaaaaa attgaatatc gttcatttga tttggaatga
    21361 tggacactac aatatggtag agttccaaga aaaaatgaaa tatcagcggg cgtcaggtgt
    21421 agactttggt ccagttgatt ttgtgaaata tgcagaagct tttggcgcta aaggaatccg
    21481 agctacaagt gtagaggaat tagaaaaagc tttagaagaa ggatttgcga cagaaggacc
    21541 cgtaattatt gatattccga ttgattaccg tgataatgag aaattgggag aaacaatctt
    21601 accagatcaa ttctattaag gaagtgtcga catgactgaa aaaatcttat accagcacgg
    21661 gacattagga gctttgatgg ccggcttgat ggatggaaca gaaacgattg ctcatatatt
    21721 agaaaaagga actctgggat tgggaacatt gcatgggctt gatggtgaag tcatcttttt
    21781 agatggcgta gcttatcaag gaagatcaga tggctcagtt gcccaattag atggaagtga
    21841 acttaccccc tatgcagcaa ttacagattt tacgccagat actagttttt ctgtctcaaa
    21901 aactgcagat ggagaacaat tgaaaaaaga catattagta agagaagccg gggaaaacct
    21961 atttttggca gtgaagataa ctggattatt caaaaatatg cacatccgta tcatgccgaa
    22021 gcaagaaaaa ccttacagaa gactagcaaa aatttcagag tctcaaccag aattccaaca
    22081 aagcaatgtc caaggaacat tagtcgggtt ctttacgcct gaattattcc aaggagttgc
    22141 tgcagcggga tttcacctgc attttatcga tgatacacat acatttggcg gacatgtaat
    22201 ggattttgaa gtggctgaag gaaaagttga gattagccgc atctcgtccc ttgtacagca
    22261 ttttccagtt gatgatccga cttttgttca cgaaacgatt gattatgctg atttagcagc
    22321 agaaatccaa caagcagaat agaaaaagac agcgagatgc gttcaaggtg attaacctga
    22381 cgtatctcgt ttttttgagg agaaaaccta gcgtttacaa aaaaactgag ctataatctt
    22441 ctccatagat caaaaaggag cggtttttat catgtggaca gaaaaacaga aaaaagatgc
    22501 atacgaaatt ttattattac agcaacaagg attattagaa gcagaagata actggttagc
    22561 aaatttagca aattcatctg cattgttgaa tgagactttg cctgagactg tctttgcagg
    22621 atattattta ttcgatggta atgaattgat tttaggaccg ttccaagggc gagtttcttg
    22681 cacacgtatc aagatgggaa aaggagtttg tggagaatca gctgaaaaac aagaaacatt
    22741 gatcgttgat gatgtcaaaa cccatgcaaa ttacatttcc tgcgattcag ccgcacaatc
    22801 agaaatcgta gtgccaatgg taaaagaagg taatttaatc ggtgttttag atatcgattg
    22861 cggagtaacg aaagggtatg atgaaatcga tcaagcattt ctagaaaaat atgtagatct
    22921 tttattagca aattttaata taaatgcttt ttcatttatt aataactaaa atcgtctatt
    22981 gaaacaaaaa agaagagaaa tcaagaataa aaagagccgg aaagacagtg ggcatttctg
    23041 tttttcggtt tttttatttt tttataaaat cacaagtgtt attgattttc ataatcatat
    23101 tttaatgtta ttatcatttt a
//
LOCUS       DADVXM010000040        22723 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.041, whole genome shotgun sequence.
ACCESSION   DADVXM010000040 DADVXM010000000
VERSION     DADVXM010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.041"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            133..3660
                     /locus_tag="KB927_001605"
     CDS             133..3660
                     /locus_tag="KB927_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBB6840525.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="KB927_001606"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="KB927_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBB6840526.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="KB927_001607"
     CDS             7448..7789
                     /locus_tag="KB927_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6840527.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="KB927_001608"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="KB927_001608"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBB6840528.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="KB927_001609"
     CDS             9146..11566
                     /locus_tag="KB927_001609"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBB6840529.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="KB927_001610"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="KB927_001610"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBB6840530.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="KB927_001611"
     CDS             13000..13737
                     /locus_tag="KB927_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6840531.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="KB927_001612"
     CDS             13751..14566
                     /locus_tag="KB927_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBB6840532.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="KB927_001613"
     CDS             14579..15226
                     /locus_tag="KB927_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6840533.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="KB927_001614"
     CDS             15242..15898
                     /locus_tag="KB927_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6840534.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="KB927_001615"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="KB927_001615"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBB6840535.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="KB927_001616"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="KB927_001616"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBB6840536.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="KB927_001617"
     CDS             18240..18758
                     /locus_tag="KB927_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6840537.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="KB927_001618"
     CDS             18865..19365
                     /locus_tag="KB927_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6840538.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="KB927_001619"
     CDS             complement(19645..20565)
                     /locus_tag="KB927_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBB6840539.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="KB927_001620"
     CDS             20730..21743
                     /locus_tag="KB927_001620"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBB6840540.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="KB927_001621"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="KB927_001621"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBB6840541.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
BASE COUNT         7572 a         3957 c         4832 g         6362 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aac
//
LOCUS       DADVXM010000041        22376 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.042, whole genome shotgun sequence.
ACCESSION   DADVXM010000041 DADVXM010000000
VERSION     DADVXM010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.042"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(177..695)
                     /locus_tag="KB927_001622"
     CDS             complement(177..695)
                     /locus_tag="KB927_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBB6840542.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(697..1314)
                     /locus_tag="KB927_001623"
     CDS             complement(697..1314)
                     /locus_tag="KB927_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBB6840543.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(1311..2165)
                     /locus_tag="KB927_001624"
     CDS             complement(1311..2165)
                     /locus_tag="KB927_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6840544.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIILLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(2162..3073)
                     /locus_tag="KB927_001625"
     CDS             complement(2162..3073)
                     /locus_tag="KB927_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6840545.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(3114..4448)
                     /locus_tag="KB927_001626"
     CDS             complement(3114..4448)
                     /locus_tag="KB927_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6840546.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            4656..5486
                     /locus_tag="KB927_001627"
     CDS             4656..5486
                     /locus_tag="KB927_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBB6840547.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(5730..6012)
                     /locus_tag="KB927_001628"
                     /pseudo
     CDS             complement(5730..6012)
                     /locus_tag="KB927_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011066964.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6170..6364)
                     /locus_tag="KB927_001629"
     CDS             complement(6170..6364)
                     /locus_tag="KB927_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840548.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(6869..7054)
                     /locus_tag="KB927_001630"
     CDS             complement(6869..7054)
                     /locus_tag="KB927_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840549.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(7904..8245)
                     /locus_tag="KB927_001631"
     CDS             complement(7904..8245)
                     /locus_tag="KB927_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6840550.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(8245..8475)
                     /locus_tag="KB927_001632"
     CDS             complement(8245..8475)
                     /locus_tag="KB927_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6840551.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            8762..9100
                     /locus_tag="KB927_001633"
     CDS             8762..9100
                     /locus_tag="KB927_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840552.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(9305..9544)
                     /locus_tag="KB927_001634"
     CDS             complement(9305..9544)
                     /locus_tag="KB927_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBB6840553.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(9520..9867)
                     /locus_tag="KB927_001635"
     CDS             complement(9520..9867)
                     /locus_tag="KB927_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBB6840554.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(10599..11180)
                     /locus_tag="KB927_001636"
     CDS             complement(10599..11180)
                     /locus_tag="KB927_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6840555.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(11363..11989)
                     /locus_tag="KB927_001637"
     CDS             complement(11363..11989)
                     /locus_tag="KB927_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6840556.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(12011..13342)
                     /locus_tag="KB927_001638"
     CDS             complement(12011..13342)
                     /locus_tag="KB927_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBB6840557.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(13497..13898)
                     /locus_tag="KB927_001639"
     CDS             complement(13497..13898)
                     /locus_tag="KB927_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBB6840558.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(13984..14190)
                     /locus_tag="KB927_001640"
     CDS             complement(13984..14190)
                     /locus_tag="KB927_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840559.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(14285..15787)
                     /locus_tag="KB927_001641"
     CDS             complement(14285..15787)
                     /locus_tag="KB927_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBB6840560.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(15805..16260)
                     /gene="argR"
                     /locus_tag="KB927_001642"
     CDS             complement(15805..16260)
                     /gene="argR"
                     /locus_tag="KB927_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBB6840561.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(16358..16975)
                     /locus_tag="KB927_001643"
     CDS             complement(16358..16975)
                     /locus_tag="KB927_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBB6840562.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            17196..18569
                     /locus_tag="KB927_001644"
     CDS             17196..18569
                     /locus_tag="KB927_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6840563.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            18644..19756
                     /locus_tag="KB927_001645"
     CDS             18644..19756
                     /locus_tag="KB927_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBB6840564.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(19828..21465)
                     /locus_tag="KB927_001646"
     CDS             complement(19828..21465)
                     /locus_tag="KB927_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBB6840565.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(21633..22241)
                     /locus_tag="KB927_001647"
     CDS             complement(21633..22241)
                     /locus_tag="KB927_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6840566.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         6553 a         4547 c         3881 g         7395 t
ORIGIN      
        1 aaacaccaat tatacaacat ttattattaa aattaaatta taaaatttta taacgttctc
       61 atttaacaaa acttaagtta ttaagacaaa tgaataaaca actacgcttt cctcgaaaca
      121 aaaaaataaa gcacaaatgc gcatttacgc actcatgctt tattcgtaca attaattcag
      181 ataacggcag cgcataggat gccaataaca cttcctaaaa tagctcctcc taaaatgtca
      241 gtaggataat gtaaaagtaa aaaaatcctc gaataagcga tcaaacaagc aaataaaaag
      301 gctaatattc ctgcaactgg acttaattcg aacaacgcag ctactgataa aaaggctagc
      361 gctgtatgtc ctgaaggaaa agaagaagtc ttcggtttac ttgtgtaaag gacaagccga
      421 cgattttttt cataaggtct tttccgtctt gtcgtttttt tgataaaaag caaaccaaca
      481 aaaaaataga tcaaactgcc gataagaatg gctagaccat attctctagt atcaggtatc
      541 aagactaaaa cagcagcaag gagcaaccaa ataaaaccac cattagagat attactgata
      601 aatttcaaaa aattgatttt tcgactatcc gttttccgtt gcttggcgaa cttgttgata
      661 atactatcat cgattttagc aatcaaacgc aacatgttat tcctcctttt taagaacctt
      721 ttcttgcgta cgatggataa aaagcaggac ttgaaaataa aacaagaaac tgaaacctaa
      781 taaagcaaaa tagattggtc ctgcaaacca gaatgcgaca agaaggatca acgtgcctgc
      841 caaatagaaa agcgcgcttt tgaaatcatt aaaaaacaag aaaaatgcag taatccaaga
      901 agcttctttt tgttccagtt gaagcaagat tttgtaacta aagagaagcg cgcttaatag
      961 aagcaaaaac aacgtagtat acatcaatgt atagccaatt cccccacccc aatagcggaa
     1021 aatctgatag tcgatcaata gaagaagaaa ataaacactt gctaaactat cttgctttcc
     1081 ataaagagag aagttctcac gaaacttttt ccagaatagt gaaccgagct ttttctcttc
     1141 attttttttg taatgataaa tcatatacag aactgttcga cttgcagttc ctaatgtgaa
     1201 aacaggcaag acgcacagga accatagtag ctgtaaatgg ataagacgtg gaatccattc
     1261 aatgatttct aagaaataat cattggcttt tttaccaatc gatcgattca tcatcctttt
     1321 gaacctcctg tcaaatccat cccttcaatg aaataacgtt gtgcaaaaaa gaacagcaaa
     1381 atcgtcggga tcaagacaag tgttgctcct gccatcagat aattccattg tgtcgttgct
     1441 tggttctgaa aaacttgcaa gccaatctgt aacgtgtatt tttcttgatc ttggatatat
     1501 aacagaggac ctaagaaatc attccaagct gcgttgaagg aattgatcgc aatggtaatc
     1561 aaggcaggtt tcgtcaatgg aagcatcaaa tgactccaaa tatacaaatg attcgctccg
     1621 tcgatttcag cagcttcgat caattcatta ttgatcgata agtaaaattg acgcatcaga
     1681 aatatattga acgcattgcc gaagaacgat ggaacgatca ggggcaaata agtacctacc
     1741 cagccgatct tggagaataa tacatattga gggatcatcg ttacaaaccc cgggatcatc
     1801 atcgtagaaa gaaccaaagc aaacatcagc tttttcccag gaaaatcaag cttcgcaaat
     1861 ccataagcaa taaaagaatt tgaaaggaca ttaccgatca ctactagcac agtgatgaat
     1921 aatgtatttc ttgcatagcg ccaaaaagga aaggcggcaa tcgtatccag atagttttcc
     1981 catacgattt tttctgggaa aaaggtcgga ggataacgaa cgatttcttc cattggtttc
     2041 aatgaagtaa acaccatcca aagcaataga atgatcaaaa tgattcctat tactgtcatg
     2101 aggacataac ttagtatttt ttttgtttgc cgattcacac tggtcttttt gaaataatcc
     2161 atcatttgcc gtcacctcca gaataataga cccacttagg tgcaagcttc aaattgacaa
     2221 acgtcagaac caacacgatc agaaacagga tcattgacat agccatcgca taacccatat
     2281 caaaagctac gaacgccttg ttccacatat gcagattata aaaaagcaaa gaatttgcag
     2341 gtccgcctgt tccatttttc gtcatgacat aagcttcttg aaaaatttgg aaagaaccga
     2401 tcgtagaggt gatcacatcg taaaaaataa taggagtgat taatggcaaa gtaatacttt
     2461 tgaactttcc ccaaacgcct gctccatcga tttctgctga ttcatataaa gatctaggaa
     2521 cattttgtaa tgtagctaag taaagtagca ttgctcctcc agaactccat attttcatca
     2581 aaatcaacgc aggtttcgtc cattgtggat caaacagcca agctggtcca gggatatgga
     2641 accagcccag aaatgtgttg atcaatcctg cagatggaga aagcagctgc atccataaga
     2701 tgtagactgc tactcctgat aagactgccg gtaaatagaa agctgtacgg aatacactga
     2761 ttcctttgat tttttgattg agtactgtgg ctaaaaacac actgaaaatc gtcgtcagcg
     2821 gtacattgaa gatgacgaaa taaacggtgt tgtataacga tttccaaaat aaatcatcgt
     2881 gaacgaacat tcttttgaaa tttgctagac caatgaaatt catcttggat gtcaaattat
     2941 aatcggtgaa actaccaata actgaaaaaa gcataggccc tagcataaat accaagaacc
     3001 cgataataaa aggcgagata aataaatagg cccatcttgc ttcttttttc tttcggatag
     3061 ataaacgctt caaattttct tgcctcctct gtacctagac agtcaaaaat ggattattga
     3121 ttttgcttga ctaagttttc tactgctttt tgtgcatctg ccaatccttc ttttggtgat
     3181 tttgttccta aaagaatctg gtcaatctgt tcattcacta atgtcgtgta atccggagca
     3241 tctaaaggaa ctggtgtgat caccgtattt ttaaagtttt cgtccgccat ttgatagatc
     3301 atttttcctt tatccgttag gttgtcatta ttcactaaat tctcattggc tgtcttgctc
     3361 gccatgatat caaaactttt ttcgccgaat ttttcttgta cttctggaga agaaagatat
     3421 ttgatgaatt cataagaggc ctcaggatct tttgctccgt atggtacttc caagacgaat
     3481 ccgccacccc acgaccaatg gcctgaacct tcttcttttt ctgggagctg catcacgcca
     3541 aaatcaaaat catccggtgc attttccatc aaactagagt aataattgat attttgggca
     3601 cgcatggcta ctaatccgga aataaatgga tcagatacac cagacccaaa ttcggcttct
     3661 aatttattga tcgtattttt cccataataa tcttgccagt cttggatcca ctccaaggct
     3721 tccactttat ttttagtatc aatcttgact ttttcatctt tgtcaaacca actagtcccg
     3781 ttatctgcgt ttagcgccca tacatcagcc cctaaattcc ataatggata aaaaccgatg
     3841 cgtgtaaatt cttttccttc ttttttatct agtttacgtg ctgtttcttc taattcatcc
     3901 caagttgtcg gtagatcttg ttcactgatt ccagcttctt taaataactt tttattataa
     3961 aaaatgactt gtgtatctgt attgaatggg atcgcataag gatcaccttc atattctact
     4021 gtatcccaaa gctgcggata aaaatcctta gaagtgtctt tttctacata tttggagaga
     4081 ttagttgctt gctgtgcttc tgctctttgg gcaacggaat ttatgtcctg tacaataaca
     4141 tcgggtgcat ttccagctgt tattgcagat aaagatttag tccagatgtc accccatggc
     4201 tgatacttat aatttacatg gatctcgttt tgtgattgat tgaaatcctc aatgatttct
     4261 tcgatagctt cttttcgtgc accggatccc caaaaggacc agaaatcaat attttttctt
     4321 ccatcacttg ttttttcaga agaatttgct gcacttgaac tggcatcgct tgcattactt
     4381 gatccgcatc ctcctaataa aaacaatgct gaacttgcca gcaaccctgt aaacaataat
     4441 tttttcatat tttacctcca aattttaatg taaccgatgc cggttttaat ataacgatat
     4501 cattttgttc tgaaaataac aatttataag gtatgattct aaaaaaatta ttaatgatac
     4561 caatacttta tataattcgc gagcgctttc tttgaatttt ttaatctttc gtagcagaat
     4621 gagaatgtat taaaaataga ttaggaggaa ttttgatgtt tagacaccag aaagaattgc
     4681 agtttgaagc aaaaccagat cgtccgaatc cattaatcgc gaaatatctg caggagctga
     4741 tcggcggcca atatggcgag atgagtgtag ctatgcagta cctgttccaa ggctggagct
     4801 gccgaggaga agaaaaatat aaagatatgc tgatggacat tgcaacagaa gaaatcggcc
     4861 acgtggaaat gttggcgaca atggttgctc gtttattaga gggtgcgcct gttgaagatc
     4921 aagaagcagc gatgcaaaaa gatccaacaa tcggtgccat tatctctgga atgaatccac
     4981 agcacgcgat cgtagctggc ttaggacctc gtcctgctga cagcgtgggc aatccatgga
     5041 gcggtgccta tatcattgcg agtggcaact tgttagcaga ctttagagct aatttaaatg
     5101 ccgaatcaca aggaagactt caagtagcac gtatttacga aatgatcgat gatcgtggcg
     5161 taaaagatat gctgtctgtt ctccttgcaa gagatagcta tcatcaaaat ctatgggaat
     5221 gtgcagtgaa agaattagaa gaaaaagaag gttcaatctt agtcccaagt actttcccgc
     5281 gtgacaaaga acgaaaagac attgcttatg acttctataa cttctcagag ggagaccaaa
     5341 gtagtgaagg ttcttgggct agtggcaaag cactggatgg cgaaggcgaa tatcaatggt
     5401 tgaaagaacc taagatcgaa ggcgctgcac caaaattaga accagtaaca ccaaaaatgt
     5461 atgggacacc tccattcaag aaataaatat ctacccgtag aaacacccgt tttttgttcc
     5521 acacgctttg tgagcaaaac tgactaaagt cattaatcat aaccaccctt caaaagggtg
     5581 gttttctcta gagctataag ctcaaatcac cggccagcgc ctaaagacgc tggctttcat
     5641 attttatgtt caagccatat tgcctttgcc agttttgccc acctcttaaa aggtttatgt
     5701 actactcctt agcccttaaa aggatcgtct tactctcgta cactcagctt atctaacgca
     5761 ctatcatgtt tttcttgttc ttgaatgtac tttttgatgg tcgcttcatt ttgtcctact
     5821 tttgtcacat agtatccttc cacccaaaag tgtcgatacc caaatttata ttttagattt
     5881 gcacaatctc ttgatgatct cctgaatatt ggctcgatat tgattataaa ttatttttct
     5941 tctatacttt ggtgtgaata caatgtggta tttacacatc tactttgtac gggctaaact
     6001 atttcccttt attgctccac ccgcatagca agtggttttg tatttcaatc gctcggcgcg
     6061 ctcaattagg tctaaagaca ataaatctaa aaacccgctg cttcactgac agaaacaacg
     6121 ggttttcaga aaaaaatgaa atgaaaaaga tctcttacgg caatctattt tatttttttg
     6181 attttttata aatggaaaat gcttcaagaa gtccaagaaa taaagccgta taaaaacaag
     6241 aacctatgaa atctttattt attagatatt caacagaaat cccgataaca ctagccaaca
     6301 atatatttat cagaagtgta aaataaggat gctttttata gaatagaact agtgttgttt
     6361 tcatagactc tcctttcttc atatttccaa ttaatcacaa attcacggca ttactagaaa
     6421 aattaaaggg gcgcagaagt ggaaaaatac tcttcgactt tccctacaaa ccaggccatc
     6481 ttgtgtttaa taactatacc aaatctaagg tacctctaaa tctaaattcc atttgtggcg
     6541 gtgacctcca atttttaact cttctatctc ccatccagta tacataacct tgatacttcg
     6601 accacttata tatcgaacac acaaatacct atccattgca ggagtactac ctaacttagt
     6661 tgctacttgc atctaaataa cagctgaaaa gataggactt actcttagta aagtatctga
     6721 actattaatt tttaaactat catttttatc ctcaactaca tgcacatctg ttgcaacttc
     6781 actttctgtc tcatccagat aaatgattaa ggaatcggga attgcaatat cttcagctga
     6841 cgctggaata gttgagctaa attagtcatc atatctttat tataaaataa ccaacagcaa
     6901 aaaatacaat gaaaaacaaa cttggaacta atgtatcatt aataaatgtt gaaaaattca
     6961 gcaactcatt actgtatgat tttagcagcc caaccaacat ataccctata aaagctaata
     7021 agatggttag gaatccttta gaatttttac tcattcatag acacttcctt aaataacttt
     7081 tattatagaa ggtattgtaa ataataatat tgacaaaaag tgactcaaaa taaaaaaaaa
     7141 cttacattat actggaatga actgtattga tagtgtacct aaaagctcta ctgacataag
     7201 atcgtgtaat cggtaaagta attttattaa ttatacggga tgtaatcaat tagagaataa
     7261 actaatcata aaaggtactt ttacattcat aattgtcgct ttgagattct actttggttc
     7321 actatctgac ccaattgcac attttcgatc attacaagta ttggtgtcgt tagaacaact
     7381 aaataaaaac tagcggtaga tttttcagaa tctatgctaa tttctgtatg gatgttccag
     7441 tgatggcaaa tttctctttt cattgttttt cttgtcgcat gatatgcctt tttgtgttat
     7501 tcagttaaac tatagaaatt ctttcctaga cagatcttga tcccaaattt tacgtttttg
     7561 agcatcgata tagtttaaaa tgacattact catatctaaa gagtttagat tttttaggac
     7621 taaaactgtc agttgttctt tttcttcttt ctgttaaagt attgtcgcga cttttcgtat
     7681 acgttaagat atgtcgtgaa aaaacaagtt ttgtgacaca aaaaaacgaa tgacttgagg
     7741 aaatcacctc aatcattcgt ttaaaatgct atatattctt tagtttaaga tacggaaatt
     7801 aatgccatcg accacactag tagaatgaac gacatttact tggccttttt ttaatttcgt
     7861 tatgtttagc atataaaaat attatagagt ttacttacaa tgcttaaaac atatactgta
     7921 taatctgatc aattttagcc atgtcttgca atggtaagtt ttctattttt ttgagttttc
     7981 gttccttaaa atcaagagat tttaattgtg taataattac ttgtcctttt atatctagct
     8041 cttcaggtaa tgagtaacgt gtcggtaaat tctttatagt ggaagtaatt ggacatatga
     8101 ccgaaaacat tgttttacgg ttaaattcat aacgagagac gactagtcct ggtcgtcttt
     8161 tttgaatttc ttttcctacg gagggatcaa aatcaatcca tacaatatca ccttttttag
     8221 gaatataaat tctttcttct gacactataa aatttctctc ccttcaggag ttaaatcttc
     8281 ccattcgtct ttctcataat actcggcctc ttccccacca ctaaatggat cttcaatttt
     8341 tggaactaac gtaattgttc catcatcaga atacacaacg atatattctt ggttttctga
     8401 aggtttcttt ccgttatcag aaggtaaagt taccactaca gaacttcctt gtaatctaga
     8461 ttttgtaaca agcattatca tcactccctt aataaaagta tactatataa cactaagtaa
     8521 cgcaaaattc ccctttgtaa actatctaga aaattgtttt gtttaaagta tatcttattg
     8581 gatataaata gaaataaatt gtagccagtt cattttttct ttaactaaaa aaataatcca
     8641 agaaacattg aacctatgga tccaaaagct acccaaatac tatagctaac cccccgctac
     8701 cttcaatttt gcagataaaa cgctttggga gaaaatttca aagacaacag gccatcctat
     8761 catgcccgat tataaacaaa aagctggcta ttccttttgc tctgacaaat ttcaattggg
     8821 aaagttcacg aaactagcag gtgaagaagt ttcaactgtt cggatcaaag aatgcccgct
     8881 tcaaatagaa acattggttc aacgaatttc aactagacaa gactttgcta ttgtagaacg
     8941 tgagatcgta gctatttttg tagaagaagg gattttacat gatccaactc atatcaatgt
     9001 ggataaatgg caacctctta tctataaatt cagagaatat acaactgcca accagtcgtt
     9061 aactttgaat tttagattcc aagaattcaa agagtcataa tgataaacat cgttaggtat
     9121 aaataaaaaa gactcgcagc acgagtaaaa aacaaataga agctatacat tagaaaggtc
     9181 gactgtgacc ctatagatgc agtatatgca gcttatgagc atttcttctg ttctctttgt
     9241 ttttgggatc tgtgctgaag tctttttcgt tttttgccgc tctttctttg aaaaatcgat
     9301 tatgttatac cttctccatt actaattcag gcatctgctg agtaatgatt tttcgcgcaa
     9361 aagaaatatc tgttacccaa ggttcgattt gttcttcagt caagacaagc ggcattcggt
     9421 catggattgg tgcgactgtg cggttaggtt cagtagtcat tatgattgat tctgccattt
     9481 tttcatcctg atggctacga taaaaaccgc caatatacac tattttttcc ttatttgaaa
     9541 acataaattt gtctttttct tcattccact cattgggaaa acacaacgat tttgcaaaaa
     9601 tggttgatga aaggtctttt tttcttctac tgtctctgca cgggcattaa tcatcaattg
     9661 tcctttttta aatccggtaa atccccactt catgatttcc ggagtgagga tgttttcttc
     9721 ctcttttctt aacgtcacaa caagatttga cggaaaaact tctccagctg ctaattctgc
     9781 tgcctgcttc ggttgtttcg tctgggcttc tcgataataa ttctgaagga gctctgactc
     9841 tagatcaaaa aaataacgac cacacatcct aatccctccc aatctttttt tctatcatac
     9901 actgcaacaa gaagttcgca ccaacaaaac gctttcaatt tttgtagaac taaaaaagtt
     9961 gtgacaagtg acaaactctc cagtgaatgg tattctcctg ccaactcctc ggtcacaagt
    10021 cacaatattc aacaaacatg agaagctgct ttttgaaatt gttccttgtg actcggagtg
    10081 aaacggcagg cttacgacct ctgggtaaac ggtgttcaaa agccagtttc tcggtattaa
    10141 gccaaattta tgcaaaaatg tagaaagcta ttttcacaaa atttttctta atactcgaaa
    10201 ctaagcgact ttttcacaac ctcttcctta aacggtgttc aaaagcttgc atctgcggta
    10261 ataagcccaa ccaaacgaaa aatatgagca gctattttta tttggctgtt cttattactt
    10321 gatgcagggc agctttttca caacctctcc actaaacgat gttcaatcag ctaaccttcg
    10381 gtattagctc aaaaaacggc aaaatatgag gaactatttt gccgtttgtt tctctaatac
    10441 tcaggtcaaa gcgctgattt cacaacctct aatacacggt gttccagaag tagcttcttc
    10501 gaaaaataag ccgaaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat
    10561 ttcttgaagc tgaccacttc tgtcacaacc tctaattatt aaagaacctt ttgcgaagtt
    10621 aacaatcttt ctttgatcaa ttgaaaattc tgcctaagta gtgatagatc ctgtgtgact
    10681 ttcaacaata agatacttcc ctggatttca gcaatcaacg ctttggcttg acggtctgct
    10741 tcttcatcgg acagtttttc ttcagaaagt gccaggatat tttgtttcgt atacttgacc
    10801 cattgattga ctaattctag tagcaacaga cggtattctt catccactgt actcaactca
    10861 ataatcaaat tacctacagg acagccatga taagtgatct gtgtctcatg atcagcgaaa
    10921 atccagtcca acatttcttc taatgcttct tctggctgtt ttccagcatt taagatgtct
    10981 tcgaacaatt ctgtctgcca tacgtccata tgcgcatgga tcaccgctag acaaacttct
    11041 ttttttgaag aaaagtaata ataaaattga ccttttcctg tatcagaagc tgctagaata
    11101 tctcggattg acgtttcatg atagcctttt ttataaataa gatctttggt cgcttccaag
    11161 atcttttcct ttgttttcaa tgatattctc ctttttcatt tctcatagtc ctatattata
    11221 cagtaaattc atcatttttt cttcttaatc gtttaaaaaa gactgtgcca aattatctga
    11281 cacagccctc actataaaac tgttctcata tagctagatg ttcattgatt caagaactgc
    11341 gaggacaaaa gcaattccta tcttatgata gttgctctaa tacttcctct gttgtcatca
    11401 cttgatctgc aataaagcca aagttcgtca acgctgcatc cattgcttct tggccaggag
    11461 caccaattgc atctgtcgct accacaacat tgaatccact ctctaccaat tcacgcatat
    11521 gggaatcgct acacaagttt ccgttcattc caccaagaat tactgtgtcg attccatttt
    11581 ttctcaattg gagcgccaaa tcattgcttt ctggtccaaa gattttatga ggagagctga
    11641 tgatcgtatt ttcatccaaa taaggtttca attcttcgat aaaatcggct cctgaacctt
    11701 cttccactga ttcatattga ctttttctag caaacatctg ctgctcaagc atcatatgtt
    11761 ctcctgcacc gccaaattgc catttatggt catgtgggta aaaataatga ggagaaataa
    11821 agagtttgta tcctttttct tttgcttgtt ttaccatttc aatcatattt tcgatcgtat
    11881 tgtatttttc taagatatct tttgtcaaac caaagccacc gcctgctggt ttcaagaact
    11941 cgacttgcgg gtcagtgaga actactgctg tatttttatt attgaacatg gtggattctc
    12001 cattcgttat ttattttaat acatcattta gagcttcact cattgtcgga tgagaataga
    12061 tttgatctct caataacgta taaggaagtt ttccattcat agctagcgaa atcaagttga
    12121 tgacttcatg agaatcttcc gcatagatac ttgcccctag aatcaagtca gtttcagggt
    12181 cgactaaaac tttgaataca cctttaggat cttctaatac ttgtgcttta gggacaccgc
    12241 ttgtcatata cttgaataat ttgtaattga cgccttgtgc tttggcttgt ttttctgtta
    12301 aacctacatt ggataaagtc ggagtgataa atacactgta aggcacagct ttccggttat
    12361 tcgttgttcg tttattctcg cccttcaact gatccataat gattcgataa tcatctagag
    12421 agatataagt gaactgcaat ccgcctttga cgtctccaat cgcccaaatg ttgtctgcat
    12481 ctgtacgaag gtattcatcc acagcgattg ctccgcgatc tgttagttta acatctgtat
    12541 tttctaatcc aagtgatgct gtacttggtt ttcttccagt tgcagccaaa acttttgacg
    12601 cttggattgt tacttcttgg ccatcttctg taaaggtgac ggcagctgtt gattcttggt
    12661 ctgctacttg atctacagat acacctagat ggaattcgat tcccgcattt gtcatgtctt
    12721 ctaaaatcat ttgcgcgata tcttcatctt cacgtggaag aaattcagaa tgggcatcaa
    12781 gaacgacaac tttagatccg tattcattga acattgatgc aaattccaag ccaatatatc
    12841 cagccccgat gatcactaat ttttccggta attgttcctg atccatcgct tgcgtagaat
    12901 caatcaagta gcgacttgta ttcaatcctt tgattggtaa aatgattggt tcagaaccag
    12961 tattgatgaa aatccgttcg ccttcaacaa tcactttttc accattattc gtcacttcga
    13021 tttgatggtt agaaagaaaa cgtgctgtac cgtccatcac tgtcccagtt gcctcatcgc
    13081 tgatcatatg ataatttttg gcgcgaagca tgcccgtcaa tttttctttc cgagcaacag
    13141 cctctgtaaa gtcgattcct ctttctccat tgaaaatcaa tgatttagaa ggaatacagc
    13201 cgatgttgat acatgttccg ccatacatac gtgttgactt ttcaacgact aaaaccgatt
    13261 caccttttga agctaacgcc ttcgctaaag tcttaccgcc ctttccaaaa ccgatcacaa
    13321 tattttgata tttttccatc atttttccct cgcttctttt ttacctaccg attggtacaa
    13381 aaatatgata accgataatt gtctattctc caaatcatct gctttatttg tcaaaaaaaa
    13441 ccagacaaaa agcggtcctt tcacgttttt agtctggttc gatttccttt attcttctaa
    13501 acaatcgtta cttctacatc gatatttcct ctagttgctt tggagtaagg gcagaattca
    13561 tgcgcatctt ctgcaatttt ttgggcttct tcttcgctga tgccatcgat atgcacttct
    13621 aatactacac cgatctgata gccgccatca tctaaattat aaagagagac acgtgctttt
    13681 actgtggact ctgctgtcat tcctgcttct ttgatcatat gttgtaccgc cccattgaaa
    13741 caagaagcat aacctgctgc aaataattgt tctggatttg ttccttctgc atggattcct
    13801 ggaggagtga ttttcatatg catcgagcca tttggtgcct cgacttctcc attgcgcccg
    13861 ccatggttga tcattgctgt ttcgtatgct tttttcattg tactgctcct ttcgattgac
    13921 catttgctac ttggctataa ttatagtgta tgacaagtaa ggcgctttct acaaaaattc
    13981 tgcttattcg aataccagaa tgccgtcttc tactattttt ccaaaaaaca aaaaaatact
    14041 actcgtgaac aacagcgtca tatttgttcc aaaataaata gcaatctttt ctacataatc
    14101 ttttatatga ttgattttaa gatacatata taccagaaag ttgaccccat aaaccaatac
    14161 tgttaaaaaa ataaccatat tcgttaccat tttttcctcc ttttgctggt ctccctacca
    14221 gcactcgatt taaccatacc actttttttg ccgtccaagc aactagcctt tcaaaaagac
    14281 tggtttattc tgctgttaat gattcaagat cagaaaaatg tccgaataat tttgctaatt
    14341 ttactaacgc caacttgttc tttccgaatt catcattttc tatctgtaat actagtaacg
    14401 gctcatgtaa gcttaaacgg atcaaaaacc agccgtttcc gtatggctct tctagatcat
    14461 atcgaatacc ttcttcattt tccgggtcga agttcatccc tttttcttct tccaacagtc
    14521 gcttcatttc ttctaatatc ttgtttcctt gttcgcgtgg ttcatcgctg aacaatttta
    14581 atcggatttc ttgtacttct acgggctgtt tcaactcttt gatttgttca tctaatgtga
    14641 taccttttct ttttaattct ggcaaaagca tcaggatctt tgcgatgaca tatgcaccat
    14701 catccagaaa atagttttcc ttgaatgcag cgtgtccgct tgtttcgatg gctagctgtg
    14761 tatctttccc aagacggtta agttctaatg ctttattgat tacatttcga tagccggaaa
    14821 tataacgaac ttggatgcct cctttttctt caatgaatct ttgtagatga gaagaagtag
    14881 gggaattcgt cacgattctt gttcctggat gctcttttaa tacgattgta cttaatactg
    14941 cgatcaaatt atttcgattg atcactgttc cagaagcact gacaactgca gaacgatcca
    15001 catctgtatc gaaaatgatc ccaagatctg cttcatttgc taaaacagcc tgcttgatac
    15061 tttccatcgc ttctttatta tcaggatttg ggatatgatt aggaaatcgg ccatctggtt
    15121 ccaaaaattg ggaacctgtt gaatccgcac ctaagctatt caatactttt tcagcaaaga
    15181 atccaccagc accatttccg gcatcaacaa tgattttcca accatttagt ggtttgcttt
    15241 ctagtgttcc aatccccttt ttaatttttg tgactaaatc ttgcgcataa ggtgtcaaaa
    15301 ggtctgcttt ttctacgctt ccagtttgtt cgctttttat tttttgctgc tgtgatagga
    15361 taaaagcaat atcttctttt tctgctcctc cttctgaggt aaagaatttt attccattat
    15421 aataataggg aagatggcta gcagtcagca taaccgcagc atcgcacgag aactgttcaa
    15481 attgagtgga cataaacata gcaggcgtag tagctaattc gaaatcgatg acatgtatcc
    15541 cttgttcttt cagactttgg atcaacgcct ctttcagtgc tggtccgctt atcctactgt
    15601 catgaccaat cccaatcgtc cattttttat ttggatcggt tgatttcttc tttttcttta
    15661 tccagtttgc tagtccccag ccgatctttt ttaccatgtc tgtcgtcaag tttacttcat
    15721 atccttcaac tggtaatgcg attcctcgaa tatccgatcc attttgcagc gctttcatat
    15781 ctttcatata aaagtcctcc tcatttattc cctcattttt tccagctttt ctgcaaatcg
    15841 ctgtgcttct tcttctgagc ggcaaataat aatgaatgta tctacaccgg ccatcgttcc
    15901 gacaacttca gggtaagcca cttcatctag ccaattcgtt accacatcgg caccatttcg
    15961 ttcagtcaat acgataacca tgaactgaac agactggata cgcaaaacct cgcgtctaat
    16021 tgctgtacgc aaacgttctt catttaaaga aacagatggc tggttaaata atgtatagcg
    16081 tactattttg ttttcatttt gactttttac taacttcatt tctcgaatgt ctcgagaaat
    16141 cgttgcttga gtcacatcgg cgcctgcttc atgcagccgc gcaagcagct cttcctgtgt
    16201 cccaataggt tgttctgtaa tgatctggcg gatcagtgct tgtcgctgtt tctttttcat
    16261 attagacacc tctcaatgtt gattatagca aaagataagt aatatttctt catattttgg
    16321 tattttttac ttttattttt tgttttcatt caggttgcta acctttttct attttaacac
    16381 gcaaaatcgt cttcattttt tcaggtgctg attttcttgg atcgctgatg taaatctctt
    16441 tgtgttcttt agaagctctt tcatagcctt cttttgcgat gaatgcttct aatttctcaa
    16501 acgttgctgg ttcttcggca tagggcccga cgtgtaagat ttgggcacaa agaccttctt
    16561 ccatcttttt gaatactact tgttctttca agtcttccgg aagtttgcta gaacgctgaa
    16621 tggcttcttg tgctatcgct tctgtaacaa agtcaggctg tcggatcatc aattgataag
    16681 aaaaatgttc ttttttcatc actggttcat gcaaatactt ttcttgcagt ccccattgtc
    16741 cttccagtgg atagacagta tacatctgat aatcaggaat cagccaattt tttttaggcg
    16801 acatgcgtat tgcatagctg actgcatata gacaggctac tcttcgttta aagtcttcct
    16861 gattcgggtc gccgatccct ctgatgctaa agaatgattt tttaggaacc tctagtattt
    16921 gcgggctttt tttcatacta tagctcttgt ctttacgcca ttcaattttt tccatttttc
    16981 ttcctccgcg aaattccatt tagttattta ttatcatacc tctttttgag tgacttggct
    17041 aatcgtgttg acactatttt tcagtttgtg ctagaataag tgaagtaaat aaatcgtaca
    17101 gataacacgt ttcggcgtgt cgagagagag gcggtttcta tttttataat agaaatcact
    17161 ctcttttttt acgaaatttt ttagaggtga tgtaaatgac aaaacaaaaa cagctgcttt
    17221 tagtacctgc agtaattgca acagggatga tgtcttttgc gggcgtattg atcgagacgg
    17281 ccatgaatgt aactttccca actcttatca gacagtttga tttaacgact gcacaagtcc
    17341 aatgggtaac aacgatttat cttttgatga tttcgatcat tgttccgctg tctacttatt
    17401 tgaatcgcaa ttttagtctc aaaaaactct ttttagcttc aaatctgctt ttcttggcag
    17461 gtataatgat cgatttcttc tctcctacct tcatggtcct attgtttggt cgattgctcc
    17521 aaggtgcagc gacaggtatc gctcttccgt tgatgttcca tattatcttg acatttgccc
    17581 ccctcaatcg acgaggcgcg atgatgggtg tcggtacttt gacaacggcc attgctccag
    17641 caattggccc cacttatgga ggcattatga cttcacattt tacatggaat catatcttcc
    17701 tgtttcttgt gcccgttttg attctttctt tgattatcgg ctggtttgct attcccgaga
    17761 tggcagtaca aaaaagtggt tatttggatt ggataagcgt tttaggaatt tgtcttttgt
    17821 ttagtggaag tctaacattt ttgagtacgt tgggaacagt ttccagctgg attgctttaa
    17881 tcatcggcgg tattggctgg ttcctttttt actatcgaag taaaaaagtg gagcatccac
    17941 tgatccgact gtctattctt tcaaataaaa cattccgctt gtttttgatt ggcttcttag
    18001 tttatcagtt tttattactt ggtgtatctt ttgtcttgcc gaatttcctt cagatcgttc
    18061 aaggaagtag tccttttgtc gctggattag cgatgcttcc cggcgcagcg gttggtgctt
    18121 tgctttctcc tttttccggg aaaatgctgg atcaatatgg tccgaagaag ccaatttttg
    18181 ctgggctgat tctttctttg attggttggc tagcattatt cctactcata ggacacgctt
    18241 cagtgggtgt attgattgct tgtcatgtgt tttatatgat cggtatcgga ttatcttaca
    18301 gcaatatgat gaccaccgga atgaatgcac tgaatgaaga actacaagga gacgggaacg
    18361 caatgttcaa taccttgcag cagttttctg gcgctgtggc tacttcatta gtagcggtca
    18421 ttatcaatta cgtccagcat catacttccc ataactatga agtgtctact acattaggat
    18481 caaaagcagc attaggcgtc ttgttgctgt tgcttctcgt aagctttgct cgattcgcct
    18541 attatctgtt ctttgctaaa aaagcgtaga ttccatatac ggcaggtgtt gcatctgccg
    18601 tttttttgtg tgaaaatggt tgtttgtaaa aggaggcttt tttatggaaa aaattgccat
    18661 tatcggtggc gggatcattg gtatgaccct agccagttac ttagatacat caaaattcaa
    18721 tgttgcttta tttgatgaag ggacaggaca ggcaactaaa gctagcgctg ggattatctc
    18781 cccttggttg tcgaaacgca gaaacaaaca atggtatcgt ctggctaaag acggcgctgc
    18841 ttttttccct aaacttataa aagatttcca acttgatcaa acgatttacg cacaatcagg
    18901 gacacttttg cttcgacctg aaaaagattt agctgaattg gctgttcttg ccgagaaacg
    18961 aaaagaagaa gcgccagaaa ttggaaacat cgaatggctt tcacctgaac agacatctca
    19021 agcacttccg ttattgaaac cagcagtttc actgcgtatc agtggtggtg gtcgtctgga
    19081 tggaaaagca tatttagaac atcttggtca gcgtttagca caaaaacaaa tggagcagat
    19141 ccaggcaaaa gtcactttgc ataagaagag cgattcttgg ctcatcaagg gaccgtttgg
    19201 agaatacaca gctgatcgtg taattttgac acctggcccg gcacttaagc ctttattaca
    19261 agaattaggc tatgctgcag atatacgtcc gcaaaaaggg cagctcttag catttcagac
    19321 atcttataag atgagtcaag actggcctgt tgctatgctt gacggagaag ctgatttcat
    19381 tcctttcatg gatggaaaga tccttttagg tgctacccat gaaaacgatc aaggctggga
    19441 tttggctcct actagcgaag cttataaggg attgactaag agtacagaac agttcttgac
    19501 tgatccagat cagataaaaa actggccata cgagttccgt gtaggtaccc gtgcttatac
    19561 gtcagatttt tccccatttt tcggcgtact gccagatgat ccaagcttac tggctgctag
    19621 cggtctaggc tcttctggct tgaccacagg tccttatatc ggctatctat tagccaactt
    19681 cttaaatact ggtcattggc ctacggaaga ttatcaaaag gacatctcca cctatattac
    19741 gaaaaatcca tcatagaaaa acagcttttt caagtaagga tcccgagcga tattgcgcat
    19801 ggattacttc ttgaaaaagc tgttatttta gttcaatttc tgaatcaaat tctccaaact
    19861 ttcttttgct tcatctggca agagatcttt tcctatctga gcttcaatga atcgtaaacg
    19921 aatatcaagt cgttgtttca ccagattttt ataggacgta tcctcaaaag aaacaggaaa
    19981 atctggtata ggtaaatagt ggatgtcttc aaatggacca aacgacttga attctgccgt
    20041 ttgttgcacg attctttcaa cgattgacaa tgtcgtttca ggtttgattt ttttatcatc
    20101 gaaatatcca gtattcagga catagcaggc tgtttgctgt ttcaaaaaca actctcgaaa
    20161 agcttgatag tcttccctaa gaggatagac acggaaagga ttagcaaatg gttcaatgac
    20221 tagctcatct agctgtcttt ttgtagtgat attttccgcg tctgatcgtt ttgttgctaa
    20281 tgttgcacca aaagacgctg ctaaaactgg gtcattgatc ttgataattg gcggaagcga
    20341 atcatctttc atgatccaaa aaacagcatc gatcttttcg ctaagatgat cgactcggtc
    20401 gggtgtcgca taacgtgatt tgactgtccg cccatttccg tttcgtatat ctcctgttac
    20461 taggactttt tctcctttac ttgtacatgt cacgcccaca ttctgacaag taaggaaaga
    20521 agaaatggcc ggatcatcag acggatagtc ttgtgtttta tcaaagtaag aaggttccaa
    20581 ggcagtagca aaaccatttt ttcgagaaat aacgaaagca tcgtcatgca agatcgaaac
    20641 agagtgacct tccgtatgtt ttgctaaggt aatcgttgat tttccagaac cggacaaccc
    20701 aaatacagcc atcgtatagg tctggtcatt actagcatat tgtttcatcc caccgtggca
    20761 ggcaataaag ccattgcgat ttcccaatgc ccaagcaagc gtcaaagtcg ctttttttaa
    20821 ttctccaaag taacgtaatc ctagcacagc cgctgtatta tggagagcat caaacaaaat
    20881 gagtccattt ggaaatgttt catgtgtcca ttcgggatca caaaagatat aaagatctcc
    20941 ctcatcaaag gaaacagact tttgataagt ctctaagatc ttcgaattcg ctggctgaaa
    21001 attcagcaaa taagaataca aattgttctc aaatccttct ggaatcagca aatgactttg
    21061 cacagaaaat tcttcagata ggccaacgat tacttttgta tggtaaaact ggcgcttgcg
    21121 actttgatac acagcttctc ttaaaatttt ctcgtatttg ctttgttcct tgtctaagtc
    21181 ctcaaagatc cgccgagcac ttgctgttct tcccacaatg cttccatcat tgaatactag
    21241 tgtcctaaca tcagctggta aatctagttc ttcagcatgt gagattgtta aatctgtgat
    21301 gatcgttcct ggactccctt ttgctagttg ataagctgtc ttcctatcaa aaacttcatg
    21361 aacattatta ccgtaaaatg tcgtttctac aatcgatcga atactggata acagtggatt
    21421 tccacttgtg atttcgttta attcgagact ctcttttgta ctcatggctc ctcctcattc
    21481 cctaaacaaa aaaacgtttt ctttattata cattattcga gtttttattt gtactgctgc
    21541 gctgtgggaa gcaaacgagt tatttttcac acaaaaaaac cgagaacttg aataaacaag
    21601 tttctcggtt tcatcatttt ccttttatcg gcttagtacc agccgtttgc taaccagaat
    21661 gttttagcag catcccatga accataacga gatgttacat attgttctgc tacacgttct
    21721 tgattggcag ctgaatagtc gccgtttaag tatgaagcat ctaattgata acggccgatg
    21781 taacgtccgt tagtagctgt gtatgaaccg cctgattctt tttgtgcgat ccattctttt
    21841 gcagagcttg aagttggcgc tgttgcagca gctggggcag caggagctac ttcaactgtt
    21901 tcaacaggtg caacgtatgt atgttcttgc gttgctgttt cagttgtaga tgctgtattt
    21961 tctgttgttt tgttttctgt tgttgctgaa gaatcatttg aagttgggat tgttaattgt
    22021 tcaccaacat aaatgcggtt gatgtttgcg atcgaatttt tttcagcaat tgcatcgatc
    22081 attgagttgt ctcctgcaaa tttttgtgag atcttagata atgaatcacc tgattttact
    22141 gtataaactt catcagcgtg agcatttgta gttcctacaa acattgcagt agcaccagca
    22201 gcaaaagttg tacctaaaac aattttctta aatgaattca tattaaactc ctttttttct
    22261 ccgtttttta ttctttcgac gctattaact ttatcattta gaaatatttc ataggtaaaa
    22321 gaaacatgac atttaatgac aaaataacga attatttaat atttgtaaca tttaaa
//
LOCUS       DADVXM010000042        20945 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.044, whole genome shotgun sequence.
ACCESSION   DADVXM010000042 DADVXM010000000
VERSION     DADVXM010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.044"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..888
                     /locus_tag="KB927_001648"
     CDS             <1..888
                     /locus_tag="KB927_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBB6840567.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
     gene            932..1138
                     /locus_tag="KB927_001649"
     CDS             932..1138
                     /locus_tag="KB927_001649"
                     /inference="COORDINATES: protein motif:HMM:NF018513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HBB6840568.1"
                     /translation="MLVAFIVAKKNKYPVVEKGQMAHAGKIIKEAIPSLLLIVIIIGG
                     ILTGIFTAVEASAIAVIYKWVIRF"
     gene            1120..1425
                     /gene="kduI"
                     /locus_tag="KB927_001650"
     CDS             1120..1425
                     /gene="kduI"
                     /locus_tag="KB927_001650"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: protein motif:HMM:NF002091.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBB6840569.1"
                     /translation="MGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRVFHMMG
                     KPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQMDQLK"
     gene            1445..2248
                     /locus_tag="KB927_001651"
     CDS             1445..2248
                     /locus_tag="KB927_001651"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBB6840570.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(2497..3561)
                     /locus_tag="KB927_001652"
     CDS             complement(2497..3561)
                     /locus_tag="KB927_001652"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBB6840571.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(3558..4643)
                     /locus_tag="KB927_001653"
     CDS             complement(3558..4643)
                     /locus_tag="KB927_001653"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBB6840572.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(4656..5633)
                     /gene="mvaD"
                     /locus_tag="KB927_001654"
     CDS             complement(4656..5633)
                     /gene="mvaD"
                     /locus_tag="KB927_001654"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBB6840573.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(5626..6570)
                     /gene="mvk"
                     /locus_tag="KB927_001655"
     CDS             complement(5626..6570)
                     /gene="mvk"
                     /locus_tag="KB927_001655"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBB6840574.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            6886..7545
                     /locus_tag="KB927_001656"
     CDS             6886..7545
                     /locus_tag="KB927_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6840575.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            7630..8535
                     /locus_tag="KB927_001657"
     CDS             7630..8535
                     /locus_tag="KB927_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6840576.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(8537..9169)
                     /locus_tag="KB927_001658"
     CDS             complement(8537..9169)
                     /locus_tag="KB927_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBB6840577.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    9320..9445
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            9489..10013
                     /gene="infC"
                     /locus_tag="KB927_001659"
     CDS             9489..10013
                     /gene="infC"
                     /locus_tag="KB927_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBB6840578.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            10085..10285
                     /gene="rpmI"
                     /locus_tag="KB927_001660"
     CDS             10085..10285
                     /gene="rpmI"
                     /locus_tag="KB927_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBB6840579.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            10338..10697
                     /gene="rplT"
                     /locus_tag="KB927_001661"
     CDS             10338..10697
                     /gene="rplT"
                     /locus_tag="KB927_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBB6840580.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            11133..11474
                     /locus_tag="KB927_001662"
     CDS             11133..11474
                     /locus_tag="KB927_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840581.1"
                     /translation="MLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLIRKV
                     VELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVKSTILCKS
                     STSSKAQCFAL"
     gene            complement(11581..12768)
                     /locus_tag="KB927_001663"
     CDS             complement(11581..12768)
                     /locus_tag="KB927_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBB6840582.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
     gene            12865..13761
                     /locus_tag="KB927_001664"
     CDS             12865..13761
                     /locus_tag="KB927_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBB6840583.1"
                     /translation="MDVIGISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAA
                     ESYTYNDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAV
                     LLPVLGVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMV
                     GFLMTLAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSG
                     SAILAVVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKS
                     IPTGWIIGAILCLITFLLYGNA"
     gene            13809..15938
                     /locus_tag="KB927_001665"
     CDS             13809..15938
                     /locus_tag="KB927_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBB6840584.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            15913..16602
                     /locus_tag="KB927_001666"
     CDS             15913..16602
                     /locus_tag="KB927_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840585.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(17010..17696)
                     /locus_tag="KB927_001667"
     CDS             complement(17010..17696)
                     /locus_tag="KB927_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6840586.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(17832..18026)
                     /locus_tag="KB927_001668"
     CDS             complement(17832..18026)
                     /locus_tag="KB927_001668"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840587.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(18076..18516)
                     /locus_tag="KB927_001669"
     CDS             complement(18076..18516)
                     /locus_tag="KB927_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBB6840588.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(18520..19365)
                     /locus_tag="KB927_001670"
     CDS             complement(18520..19365)
                     /locus_tag="KB927_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBB6840589.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            19514..20932
                     /gene="pepV"
                     /locus_tag="KB927_001671"
     CDS             19514..20932
                     /gene="pepV"
                     /locus_tag="KB927_001671"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBB6840590.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
BASE COUNT         6461 a         3963 c         4340 g         6181 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt caacttttgg
      901 ggttcagttc actttgtggg cgctaggaat catgctagta gcattcatcg ttgctaaaaa
      961 gaataaatac cctgttgtcg aaaaaggaca gatggctcat gctggaaaaa taataaaaga
     1021 ggcgattcct agccttctat tgattgtcat cattatcggt ggtatcttga cggggatatt
     1081 tacagcagta gaagcttcag cgatagctgt catttataaa tgggttatac gattttagaa
     1141 ccaggaagtg cttggaatac gatgccttgt catacacatg aacgtcgtat ggaagcttat
     1201 gtctattttg attatgccaa tgaagataca cgtgtgttcc atatgatggg caaaccagat
     1261 gaaacaaaac atttagtcgt agacaatgaa caagccatta tttcgccaag ctggtcgatc
     1321 cattcaggtg taggtacaag caattactca ttcatctggg caatgtgcgg agaaaatatc
     1381 acctatacag acatggatat ggtgcaaatg gatcaattaa aataagcata agggagagaa
     1441 aatgatggaa tttagtatgg atatgtttcg tttagatgga aaagtagcat tagtcaccgg
     1501 tgctgtctat ggtattggat ttgagattgc acgctcttta gctacagcag gagcaaaaat
     1561 cgtatttaat aacttgaatc aagaatcagt tgatgaaggt atagcgcatt ataaagaagc
     1621 aggcatcgat gcaaaaggtt atgtctgcga tgtgaccgat gaagaagcgg ttcaagcgat
     1681 ggttcaacag atcaaagaag atgtaggttc agttgatatt ctagtcaaca atgcagggat
     1741 catcaaacgg acaccgatga tcgaaatgga tgcggcagac ttccgccaag taatcgacgt
     1801 ggatttaaat gccccattca tcgtttcaaa agcagttatt cgggatatga tcgaaaaagg
     1861 cggcggtaaa atcatcaata tctgctccat gatgagtgaa ttaggacgcg aaacggtcag
     1921 tgcttatgct gcggcaaaag gcggattaaa aatgctgacg aaaaacatcg cttctgaata
     1981 cggtcaatac aatatccaat gtaatggaat tggaccaggt tatattgcta caccgcaaac
     2041 tgctccatta cgcgaaacac aagaaaacgg tgaacgtcat ccattcgatc aatttatcgt
     2101 tggacgtacg ccagcagcac gctggggcga gccaatcgat ttggctggac catctgtctt
     2161 cttggcttct agcgcatctg atttcgttaa cggccatgtc ttgtatgtgg acggaggcat
     2221 acttgcctat atcggaaaac aaccttaaaa gagctttagt acaccgttta gtggagaggt
     2281 tgtgaaatca gcggcttgaa cgaataccga aggacagctg attaaacatc atttattcga
     2341 aaaaagaggc tgggacagaa gcgtttaact ccaagaaata agaaggaatt cacgaaaatt
     2401 gcttttcaaa tttttgtgaa tttcagctta tttccgaagg agttgctttt gcttccgccg
     2461 tttatacgtg tttagagcgt gggataaaag tgttctttac ttttgtccca cgctcttttc
     2521 tgtgcgtctt ccatacttca ctaagtcgat ccctcttgct tcgcaccaat ccttcactgg
     2581 tccggaaaag atcagtgatt gttggtgtag ggccgcggta ttcgttgcgc cgaccatagt
     2641 ataaagcaga cgaagctctt cttgccattg cttcatcagt ataatagttt cttctacgcc
     2701 gtgattcatc agatgcgtca gtacggttcc tgaagtaccc actgcatttg cgccgagaca
     2761 aagggcttta aatatgtcat aggcattgcg gatacctccg gaggctagga tttccataga
     2821 agtgtctgct tcatttgctt caagcaatga agagactgtc gattgccccc agtcagctaa
     2881 ataactcagt tcccgcttgg agcgacgggc gttttcgatc tgggtgaagc ttgttccgct
     2941 tcgaccgctg atatcaactg tatgaactcc taaagcagct agatcattga gcgtttctct
     3001 tgtcatgcca aaaccgactt cttttacgat gagggggacg tcaatggctg tttgagtctc
     3061 ttgaataagt actttccaat tggtaaaatc acggtctccc tcaggcataa ccaactcttg
     3121 aggtgcattc aaatgaatct gtaaggcatc tgcgtgaaac aatcggatag cttcttgggc
     3181 tctttcgaca gaagtccctg caccgatgtt ggcaatgatt ttcccgtgag gatattcttg
     3241 tcgcataatc gtataagtat cggctaaaga agggtctttc aaggcagcgc tgactgaacc
     3301 agtggcaatc atcaaatctg cttctcttgc gacgattgca agatcttggt tgattttttt
     3361 tgttttttcg cttccgccag tcatcgcatt gatataaaat gggctgctta gtgtaaaccc
     3421 aactgcctgt gtacttagat cgacatcaga aactgctatt tgcggcaaag ggttatggat
     3481 gatccgtacg aagtcaaatt cgtttttttg tttatcatga aaggctttag ctagtgaaac
     3541 atgttcgtct tttcgattca tcggttttcc tttctttgat cgctatagac atgtaacggc
     3601 agtggagtga tttctgcttt ttcccatgca ctcattaaag gaaggatgcc agatttctgg
     3661 tcaacaatta cgattccgca atcgccacca cctgcaccag aagattttgc ggctccttca
     3721 tactgttcag ctaaattaca caatttgttc aaagcaggcg tttcgatgac gaccccagtg
     3781 attgcagata aatcatgcag taattgtcgg ttttttcgaa tcatctgttg gatcaacgtt
     3841 acattatttt ctttaaaccc tttgatcatt tcgttgacac attctgtact gttttttaag
     3901 aaaagctgat aagccaccat tttgtcttct ctcgaacggt gaacttgatc gaccaaatca
     3961 gaagtagagg cagggctacc cgtccaacca atcaataaac gtaaatcttc aggagcaatc
     4021 aatggctcaa tggatagacc tggccaatcc agggcaagta actcactgat agaatgctga
     4081 gtttcttgtt cttggagcca aggatggtcg aaggttgaga aagcgatcca gccaccataa
     4141 cagctagcag cgatgtcgcc gcaggaacca ttatcttgaa ctgctaaatt ggctagtgct
     4201 gcaatcttga aaatctccaa ttgagataaa ttcaacgcgt aaaaaacatt caaggctttg
     4261 accgttgcaa cggtcacggc accgctagaa cccaatccat atttccggcc atttgaactg
     4321 tctaactcac ttgttacttt cagatcataa aaggataaaa gaatgttttt ttcttgtgca
     4381 tacttttcag tcaaacgaat agcagcaagg atataatgaa aaggattttc ccgaatatct
     4441 aaaactaatt ctccgttgcg tcttgtccaa cgtacaggca tcccactata ttgtgcagat
     4501 tggatacttc cgacttttcg tgcggattct acagtgactg ttacgaattg atcgactgca
     4561 gcgataactg ctggatgtcc tgtttcaaca actgcatatt ctccggcaat atagagtttg
     4621 cctggtgcag atacttcaat cataaaaatc tccctttatt caataatcgc aattcctgga
     4681 ccagcatggg cagtaattac ttgttctttg ctaaataatt tggtaaatgt ttcttgtacc
     4741 tcagataaat ggctgttttc cactaaaact ttgacattag ggccagcatc catcgtaaag
     4801 tagcatggaa tgcctttttt tctcaattgc cgcaccgcat ccatcgcttt taagctgtca
     4861 ggagaccagt aagtgaatgg aggctgggca gctaaagtcg ttccatgcat ttttagtccg
     4921 tttctttcca tcgtttctcc gagaagttgg aaatcttttg ttttgattgc ttgtttcaat
     4981 tgatatagat ccccttcaac ggaatctaac cagccttgat aaaaactgga tgtttcgact
     5041 gttcgacgca tcccatttct gctggacact tcttttttct ggtcgttgat caaaacgaaa
     5101 accattgcta aatcgtcttc gaaagaatcg gaagggactg gcttagcgta agaacttaag
     5161 tcgtcatggc ctttttccca ttcaacgaaa ccaccgaaaa tacttcggca agctgaacca
     5221 gacccgcgtc gagcaaatct tgaaagagag agatcgtcta atccaagctt aagagcagta
     5281 ttgcaagctc ctgctaaagc agctagcccg ctggcagagg aggctaatcc agctgcggta
     5341 ggaacgaaat tctgactgat tactgaagct tttagtgaga ggccggcttc tttacgaaaa
     5401 aggtcaagaa actgactgac tttttttgtt gctttttcgt cttgtaaggt gccatctaga
     5461 taaaattcat ctaccatata gctatcagaa aagatgactt ctgtctctgt ataaaatgca
     5521 tccaatgtta acgaaaggct gttgttcatt ggaaggatga gttcttcatt tttcttaccc
     5581 caatatttga ttagagcaat gttggtatat gcgcgtgctt tgcctttaaa cataggtatg
     5641 tactcctaat ccttgtatcc aagtttcagc agcacccgca tcttcaagtg cttgactgat
     5701 ttcttgggct tttgtttttg tttgtgctaa tgcaatcata cagccaccgc gtccaccgcc
     5761 agttaatttg gcacccaatg ccccggtatc ttttgctgtt tggatcaata gattaagaaa
     5821 atcattgctg attgtcagct tttccagaag tgactgtgat tcatccattg tctgtgccaa
     5881 cgtttctggt gaattctcaa tgattgcttg ttttgcttgc ttcgtcaagt atcctaattt
     5941 ttggatcatt tgtccagttt catgaggctg ggtttcaaag aggtgagcga catctttgac
     6001 ggcttctctt gtttgtcctt tgattcctgt atcagcgaca atcaaaaaag catcgatgtt
     6061 caaagaaaag tagtcaaaag gatgcccttt tgtaaaataa atcggctgca agctgctagt
     6121 agcggctgca tcgattccac taggattacc gtgggcgatt ttttccgaaa gctggacatt
     6181 ttctaatagt atttcacgag acaaaggaaa tgctaagtaa tcataaaaag cacgagtgac
     6241 tgctgtggcg actgcagcgc ttgatcccat tccacgttca gcaggaatcg tgctttcaat
     6301 ggtcagttgc aagttttttt ggatgtcatg ctgttttttt aagtgaatga ataatttttt
     6361 gatatttttt aatgcatgag gagcttcggc taaatttcct gaatagtagg aagaaaccag
     6421 ttgatcgtcc attgcatcca gctcttcaag gaatgcggtg acttttgttg catagaaagg
     6481 aaaggcaatc gctggttctc cataaacaac cgcgtgctcg cccatcaata tgatctttcc
     6541 gcttgattct ccttggccat agtttgccat aatctaactc cttctcacgt aaaagtgatt
     6601 tttaagcaaa aaataaagcg cccaaaacga gttgcgctgc ttcacgaatt tttttgtcca
     6661 ctaagggtct caaaaaacat tcctccttta ttttactaaa accatctcag aagtaaaact
     6721 aagaatacgt tttctaaaga aaaaacactt ttttcttaag aattttttga ctttttttct
     6781 tctttgacta gaaaaaatac aattgacact actagatatt gggggtatat ttaaaaaagg
     6841 ttggagttaa acacaatatt tagtgatgaa gtgagctgga ggtaaatgag cgtgatcgtt
     6901 ttagcaggta caattggtgc cggaaaatca agtttaacag aaatgatggc tgaacacttt
     6961 gatagtcagg cattttatga atcgattgat gataatgaag tcttgccctt attttatgca
     7021 aaccctgaac agtatgcttt tttgctgcaa atttattttt tgaataaacg ttttgcaagc
     7081 atcaaacaag caatgaaaga tgacaataat gtattggacc gttcgattta tgaagattca
     7141 ctgcttttcc atctaaatgc agatctagga agagcaacag aaacagaagt ttgtgtgtat
     7201 gatgaactgc tggaaaacat gatggaagaa cttccctatg ctgcccataa aaaacatccg
     7261 gatttattag ttcatattcg tgtatctttt gatacgatgt tagagcgtat cgaaaaacgt
     7321 ggtcgttcgt atgaacaatt gtcctttgac ccaagtctat acgattatta caaagaattg
     7381 aacagacgtt atgatcaatg gtatgaagaa tacaaagaaa gtccaaaaat ccaaatcgat
     7441 ggagaccgct ataattttgt ggaagatcct caagcaaaag aagaagtctt gaaaatgatc
     7501 gaagaaaaat tagcagagat tcgccaaacc aaagtatcca tttgatttac agttgctcaa
     7561 ataaagggta aacctttatt tgagcgactt ttttctttat actggaaaca aatgtcagga
     7621 ggatagagta tgcgggaaaa acactatttt aatcaagacc gtaatttttg gatcaatgta
     7681 cagcaaaacg atgtgctagc tgttaaaaac ttaaaagaag aatatggcat tagtgacgag
     7741 atgctgactt attctctaga taaaaatgaa cgggcgcgcg tagagtacga ttcttttgat
     7801 gaagcgttac tgcttgtatc aaatgttccg caccagcaaa aagtcgataa tcattatgaa
     7861 actagtccta tcgcttttat tttaaaagaa gacggtttgt ttacatttac cacgccgaat
     7921 accgagtacg tgattcgact aattcgatcg cttttggaac ggatgccaga catgagtgta
     7981 tacagtttat tgtttcgtac attgtttttg atttctgatt ccttttttcc tttaatcgag
     8041 gaagtgaata gtgaacgtca gcggcttaat ctgaaattaa gagaaaaaac aacgaacaag
     8101 aatctgctgc aactttcaga tttagagatc ggtttggttt acttagttac aggaacaaaa
     8161 caaaatgtag tacttttaga acaaatcaag gcactggcta tttatcgcaa gttgtcagaa
     8221 aaggaaaaag aagagttgga cgatgcactg atcgaagcac gacaagcagt tgaaatgacg
     8281 aacttagctt cgcagatttt agaccagctc tctggcactt ataataattt gctgaataac
     8341 aacttgaatg acacgatgaa atttttgacg gtctggtcgc tgatcttgac cgttccaact
     8401 attgtgacag gattcttcgg aatgaatctc cagttaccct ttacccattc cgttttcgga
     8461 tgggaaatcg ccttgatcat cagtttggtc ttatctattt ggatgcttat tgcactgtgg
     8521 cggcggattc gttgatctag tctttgatct gcaaaccaag ggcttgggcg atcacaagtg
     8581 cttgctcttg attgacgatt agtcccgcca aagaatcttg agataaagcg attgttgtga
     8641 agaaattagt cgtaaagtct aatcccttca gagaagttcg aaaccagttc gaaccggtta
     8701 actgattgtc agacaaaaaa aggtttttcc aagtgacctc ataaaattcg ctgtcttcta
     8761 attgacaatg atcgaaggag acagctttca agtttgtact actaaaggaa gccatcgaag
     8821 caatacaatc agtgaaagta cagtctcgaa gataactttc ggcaaaattc gtacctgtta
     8881 atttacattg atgaaacacg acttggtgga aactgccacc aatccactcc agattggaaa
     8941 aatcacattt ttcaaaaatg acattactgc attcaaaatg acgtaaacct gttttttgca
     9001 tcgtaagttt ttggatatga ctctctctta ataccatatt tttggcatcg agatagcttt
     9061 ggttacctcc gttgatcaga agaccagaga agatctcctc atcttctaaa taaaactctc
     9121 cctttgtaag aagaggaaga gaaggtggaa taggttcgat ttttttcatg tgggttcacc
     9181 tcgtttttct ttagtatagc aaagaagcgg gaatcactgc tagaaagcct gctaatctaa
     9241 tcattttcag aaaaggaaga caaactgtat gaaaaacatt gacaaaaaga ttagtttttg
     9301 ctatactata atggttgaga aataaaagca gaagcacccg cttctcgcct tagttgataa
     9361 tgtcactggg ctagatagtt ttcactggtt ctattaggtg aagtacgcgc gggttctgta
     9421 agagaactcg tttttttatt gccgtttatt cggtaagctt ttctttctct cataatattt
     9481 ggaggtgaat gaccatagca aaggatatga tggttaacga cggcattcgt gcacgagagt
     9541 tacgattgat cggttcagat ggtgagcaat taggagttaa gacaaaagca gaagcattga
     9601 atattgcaga acaagcaaac ttggatcttg tgttagttgc ccctggtgcg aaaccaccag
     9661 ttgcgcgaat catggactac ggtaaatacc gtttcgaaca acaaaagaaa gaccgcgaag
     9721 cgcgtaaaaa acaaaaagtg atcaatgtaa aagaagttcg cttaagtcct acgatcgact
     9781 tgaatgactt caatacaaaa cttcgtaatg cacgtaagtt cttggaaaag ggcgataaag
     9841 tgaaagcttc tatccgtttc aaaggccgtg ccattaccca taaagaaatt ggtcaaaaag
     9901 tcttgaatcg cttagctgaa gaaactgcgg atattgcaac agtggaacaa aaagcgaaaa
     9961 tggacggacg cagcatgttc ttgacgctgg caccgaaaaa cgacagtaag taatttgaat
    10021 gactaactgg ctgttggaca gccgatagtc ggataacgaa agattttgag gaggaaatat
    10081 agtcatgcca aaacaaaaaa cacaccgcgg atcagcaaaa cgtttcaaac gtactggtaa
    10141 aggcggattg aaacgcttcc gcgcgtttac aagtcaccgt ttccacggca aaacaaaaaa
    10201 acaacgccgt caattgcgta aagcaagcat ggtttctagt ggcgacttca aacgtattcg
    10261 ccaacaacta gcaaaaatga aataagaagt acaaataaca gaatctgaag atttattttt
    10321 attaggagga attatacatg gcacgtgtta aaggtggaac agtaactcgt aaacgtcgta
    10381 aaagagtgct aaaattagca aaaggttact acggttcaaa acacacttta tttaaaacag
    10441 caaaagaaca agtaatgaat tcatacaact acgcatatcg cgatcgtcgt caaaagaaac
    10501 gcgacttccg taaattgtgg attgctcgta tcaacgcagc agctcgtatg aatggcttga
    10561 gctactcaaa attaatgcac ggtttgaaag ttgctgaaat cgacatcaac cgtaaaatgt
    10621 tagctgactt ggctgttaac gatgcagcag catttactgc attggctgac caagcaaaag
    10681 aagctttggc taaataagct aaacaattat aaagaggaaa gaagataacg aaaagttatg
    10741 ttctttcctc tttttttatt tacaatcctc catcaaatga aacaggacaa taacgtataa
    10801 gtctaaaata acataattaa ggttttttaa ttgaaaactg aacatttatg gtcatccttt
    10861 aatgaaagcg ctaactacat aagttagaat gagtttgact gatatattag tttgcttatc
    10921 agaaaaacaa aatggacgga ggaataacat gagtgatatt attattggta ttttgttagt
    10981 tatctcattc tttttcatgg tctggtactg tgtaaaaggc tacaacttga tggtcggctt
    11041 ttgtcatcat ggctactgta tggatgggat tagcgctagt cggaaacacg ttttcaccaa
    11101 actcggcgat ggaagggcaa ggagtaattg atgtgttgac gcatatctat acgacggggc
    11161 cagctgagta cgccaaatcg atcttggtaa atgtcttctt tggtgccttt ttcgggcgtg
    11221 ttctagtaga tagcggaatc gcagctaccc tgattcgaaa ggtagttgaa cttggagggg
    11281 acaagccaag aatcacgatg agcttactat gtattgtaac cgctgttata ttcatgtcga
    11341 tgacaggaat cggaccagtg atttctattg cagttattgt gttgccgatc ttgatgtcat
    11401 taggtatttc agtcaagtcc acaatcttgt gtaaaagttc aacctcatca aaagcacaat
    11461 gttttgcgtt gtgaacctaa ctgccatgcc tttctttctg aggagagagg tcaggagcag
    11521 tagcgcagcg actcttgatg tctctcctca gaaagaagag actcgcacag gttcatggtg
    11581 ctaaatgtta ttcgaattaa attctaaata ttttcgtgga gaagccagcc actcagtgtc
    11641 tttttccatc aaaagtgttc caattatccg agtgatggaa ttgatatttg gaaaaatccg
    11701 aatcactcgt tctctccggc gaatctcttc gttcaaccgt tccaacacat tggttgtacg
    11761 aatccttcgg cggatatttt caggaaaaga caaaatttga atagcatctt caaagccgtt
    11821 ttctaaaatg tcgcaagcag cacttaattt tgaatcacaa ccatattttt ccaagaagtg
    11881 ctcttttctt tcacgtgtca attcaagttc agaggcttta aagatactct tcaactcgtc
    11941 ttttacatca gaagaaactt tctttggcag cttatcaaaa atatttctca aaaagtgggc
    12001 ttggcatctt tgccagctcg cacctaaaaa gttcttgcga acagccttaa ctaacccttt
    12061 gtgtgcatca gaaatgacca gttttacacc gaacaaacct cgttgaacga acgattgaaa
    12121 aacggtatcc caattatctt ccgattcgcc gtcttgaaca tcaaaaccaa gaatcgtacg
    12181 tcgtccatca gaatcaatgc cgataccaat atatacacct tttgagacaa tacgatgatt
    12241 ttcccttact ttcatataca gggcatcaca catgaaaaat ggatattccg agccttctag
    12301 gctccggttt ctccactcaa aaacaaatgg atccaactgt ttcatcagat ttgaaacgaa
    12361 tgatttagaa acagtcgcac catccgttag cagttcaact gttttagtta ctttgcgagt
    12421 ggagacacca gaaatgacca tttcaatcat ggcagcgatc aaagcttttt cgcttcgctg
    12481 atatctttca aagatagtag gactaaactt accgtctctg gttcgtggaa catgaagttc
    12541 taacgtacca attcgagttg taaacgaacg atcgtagtaa ccatttcttt gtgattgccg
    12601 ttcttctgaa cgttcatagg catttgcctg aatatattga tttcgttgtt cttccatcag
    12661 ctgattaaac atgatagtca taagtgtttt tgcggtatca ttcgcaccgc tttcgtttat
    12721 aattgcttga atttcttcgc tttcaaaagt aaaatgtact tgagtcattg atatcagtcc
    12781 tattcgagta tgttttctgc aaaaaacatt gtactcctaa ctgagatcaa tggctttttt
    12841 gatgcttcac ttttacacaa ttatatggac gtaatcggta tttcagtacc ggttgcactg
    12901 ttctcattta tgggctcgat tatggctgga atctttgcta atatcgtcaa tttcaaacaa
    12961 tatcaaacga tttatgctgg tttcaatcca gcggctgaaa gctatactta taatgactat
    13021 ttccaaattg gtatgattgg gatgattgta agcttagttg tggtactaac ggtcgctaat
    13081 atatcaatga acaaaaagaa acgctatgca atggcagcaa acgtaccagc tgaaggtggc
    13141 gacgcaccaa tgatctcatg gttagccgta ttattaccag ttttaggggt cgttctttta
    13201 gatcttcaaa tcatcttagg ttttattcta gcaggtatct gggcattgct gtttactgga
    13261 aaattgcgcg gaggttataa agaaatctgt cgtcagtttg cgaaattatt tacagatggc
    13321 gcagtcgatg ttgcaccaat ggttggtttc ttgatgacct tagcgatgtt caataattca
    13381 gctgcgtatg cttctcctta tttttcagct atttttggag attggatacc gcaatcacca
    13441 ttagtcttgg caatcgtatt tgctatattg acaccactag gatttttccg cggtccaatg
    13501 aatctagtcg gttcaggctc agctatttta gctgtcgtgt tagctgttaa tccaacgatg
    13561 tcgccagcct ttttgttccc gttatttgca attacaacga ttgctcctca gcatttagat
    13621 attacacaat cttgggttgc ttggggatta ggttatacaa aagtaacttc tcgagaatat
    13681 atgaagaaat ccatcccaac tggttggatc atcggtgcga tcttatgcct gatcacgttc
    13741 ttattgtacg ggaacgccta gtaaacaaaa cgtcgataaa aacgattaga taaatggagg
    13801 aaaagaaaat gaaacgtttt gtgcgaatgg gaattgatgt tggcggtaca catacgaaag
    13861 cagtcgcaat cgataatgcg acgcacgaaa tcatcggaaa atcttcagtg aaaacaaccc
    13921 acgatgatgt ccgtggagta gctgcaggtg tcgttcagtc ttttcaaaat tgtttgcggg
    13981 aaaataatat cagtccagaa gatgttgtgt ttgttgcaca ttctaccaca caagcgacta
    14041 atgcactgat tgaaggagac gtagcaaaag tcggcgtaat cgggatggca aaaggtggat
    14101 tagaaggttt tttagcaaaa cgacaaacta gattgaacga tatcgattta gggaataaga
    14161 aaaaaataga gattgtcaat gcattcttac ctgtcaaaaa cttaaatgta gaccgtgttt
    14221 cagaaacgat ttcttcttta gaaagagaaa gagcggaggt cttggtttct tctatggcat
    14281 ttggagtaga taatggggaa ccagaacgag ttgtttatga agcagcatct gtgaaagcga
    14341 tccctacaac gatggcttct gacatcacaa aattatatgg attgacaaga agaactcgga
    14401 cagcagcaat caacgcatct attttaccaa aaatgctaga tacggcaacc tcgacagaag
    14461 actccgtacg agaagcaggg gtcaatgttt ctttgatgat tatgcgcgga gacggcggag
    14521 taatggaaat caatgaaatg aaaaaacgac ctgttttaac catgctttcc ggtcctgctg
    14581 catcagtcat gggctctttg atgtacttga gagcgtctaa tggtgtttat tttgaagtag
    14641 gcggaacaac aaccaatatc ggggtcatta aaaatggacg tccagcaatc gattattcaa
    14701 ttgtaggtgg ccacccaaca tatatctctt cattagatgt tcgggttcta ggtgtggcag
    14761 gcggttcgat ggtacgggct aatcagtcag gaatcatcga tgtcggtcca cgttctgcac
    14821 atattgccgg tctagattat gcagtattta cggagacaga aaaaatcaaa ggtcctaagg
    14881 ttgaattttt ctctcctaaa gaaggagacc ctgctgatta cgtcaaggta gtgatggaag
    14941 acggagaaga agtgactatt acaaatacat gtgcagccaa tgttcttgga ttagtgcaag
    15001 aagaacattt ttcttatgga aatgtcccat ctgcacgaaa agccatacag gcattagcag
    15061 actattgtca tacgacggtt gaagacatcg cagagcagat catggaaaaa tcctatgcta
    15121 agattgaacc ggtgatttta gaattggcag acaagtatca cttggagaaa gatcagattt
    15181 ctcttgtagg tgtagggggc ggcgctgcct cattgattac ttactttagt aataaaatgg
    15241 gtgtgaaata ttcgattcct gaaaacgccg aagtgatttc ttctattggt gtagcacttg
    15301 caatggtccg agatgttgta gaacgtatca tcccttcgcc aagtaaagaa gatatacgat
    15361 cgttgaaaaa tgaagcgatg aataaagcga ttgaatcagg cgctacacca gaatcgatcg
    15421 aagtccacgt agaaatcgat ccacatactt caaaagtaac ggctatcgct actggttcta
    15481 cggaagtgaa agcaaccgat ctaaccaagg agatcacaac agaagaagca ctagagcttg
    15541 ctgcagagga tatgcgatta aataaaaatg aagtttgctt attggaaaat acacctttct
    15601 tttatgtatg cggcgaacag aatcgttcaa aaaatgctgg aagtcttcgg atcatcgatc
    15661 aaaaaggatt tatcaaggtc caacgtggac atgcttcatg tatgaaaaca actgcagcca
    15721 attatatgac agctgtcgaa caactttggg aagatatggc agtttatcaa actgaattga
    15781 ttgcccgacc agaattttat ctctgcttag gagcaagagt ctctgatttt acagcgacgg
    15841 atctggaaca actacagctt ttgatggatc tggaagtatc tactatggaa ccggaggaag
    15901 aagtgatcgt cgttgccgga aatatcaaac aaacataagt tagaagagtt actaaacgaa
    15961 ttacaacaga tccccgaaga aatttgggga ttctaccagt ttcggcgaga tttattttgg
    16021 aaaaagattc ctttgtccaa gcagaaaatt cttatacaac aatcaatcga ttgtggtatc
    16081 gaaacggcat gtagcatcaa aaaaaagtac ccttttgccg atgtaggaga aatctgtgaa
    16141 caaatggctg ttccaatcgt ttcctgtgaa tcagagcaaa taaacgaacg aatcactttt
    16201 gcaacttatg cagaagatga agggatccga ttgatgacgg agccgttaga aaaattaaaa
    16261 tgttcaggac tagcttcgat ctctaaagaa acagcgcaag ctttgattat tggacatgaa
    16321 ctatttcacc acatcgaagc ttctgttaag ggaatttata cgcaaagcga aaaaattgtg
    16381 ctgtggcggt tgccttttta tacacatcaa tcaaacattc gtgcattgag cgagatagca
    16441 gcgatgagtt tttcaaaaga gatgaatcaa agcgattttt cgccttatgt attagaggca
    16501 gtcttacttt ggccatataa tgaaattcgt agccaaggga tcttagaaga aataaaagaa
    16561 atagaaaaaa gatgtacgga gtatgattta gattacaaat aaagagactg tgacaaaagt
    16621 cgtgtcacag tccttttttt ccgaataaac ggtgttctcc tgtcaactcc tcggtcacaa
    16681 gtcaaaatat tcaacaaaca tgagaagctg ttttttgaaa ttgttccttg tgactcggag
    16741 atgaacggca ggctcacgac ctcttggaaa aaggtgttca aaagcttgca tctgcggtaa
    16801 taagaacagc caagttaaaa acataagaag ctatttttac ttggctgttc ttattacttg
    16861 atgcagggca gctttttcac aacctctcaa taaacggtgt gcaatcagct gaccctcggt
    16921 attagctcaa aaaaaacggc aaaatatgag gaactatttt gccgtttatt tctctaatac
    16981 tcaggtcaaa acgctgattc caaaacctct tatttgatgg gtctgtcctg aatatcttca
    17041 aaataatcgg ggtaattatg aatcacgtat tcttgctcct cgataatcat atgtaaatgc
    17101 atcgtgcaaa gaaatccgac ttcatcaaag ttatgatcaa tcattgattg aagcattgtc
    17161 tgatgttcat ctaatactcg accccagtct aattctgaaa tcgtcaaacg taaccatctg
    17221 aaacggttca agtgcgtact ataactttct agccaatccc aaatttctcg ttttccagca
    17281 atttcataac aagttcggtg aaaatcagta tccaaatcaa aaaaagcttt tttattttga
    17341 gcgatcactg cctgatcggt ttgttctagt attttttcta gtttagcttg atcttgcttg
    17401 gtcattttcg cactgcattc ttgcaggatc ggtttttcca acttttcccg cgtataacgg
    17461 gctaatgaag cagatcggat atcgattttt gaaacataag tgccggactg tggaatggtt
    17521 tttacaagct cttgattgcg cagttggatc agtgcttctc gaatcggtgt acgcccgata
    17581 gctagttgtt cttctaacac tttatcggag attttacttc cgggtgctaa ctcggaataa
    17641 atgatttgtt tacgtataga ttcataagct tgctgttgca aattattgat aaccatttaa
    17701 ccttcctttc tatgcagata taatctatta taacataaat cgcttacaaa tcgtgtgggc
    17761 ataaaaacac agtctgcaaa aaaagccctg ataggcatgc ctattagagc ctcgaaaaga
    17821 aaaatattga atcaatctgg tcgtacctct tggatcggtt tgacacgacc gccgattctt
    17881 ttagcaaaag cttcggattc ttttttgtct ttgaaaatga gcagattgtc taagtttttt
    17941 tcccgagtgc gacagccagt tttatcgatg taaccgtgca ttactttaac gacatacatg
    18001 gggatcacct gcttttttct tttcattata cgaactactc gacacaatac aagaaaaatg
    18061 cttagacggt ctttattaag aatttacatc atccaaagaa gcgtacgctt ggaataactg
    18121 ttctaactcc ggattgactt tgctcagctt cactaatcgt tgcgaatcag aaagtaaaaa
    18181 acagtgttta ctactgccag tagtttttaa ttttttgtct tcagttccca caatttcgta
    18241 gctaaaatcc aaccgtgttc ccgtatactt ttggatagtt gggtggatgc tcactttttc
    18301 tccgtaatgg atcatttctt tatagctgca atttacttcc agaacgggga tgatgatccc
    18361 agattcttcg atttttttat agggaaaccc tagatgtacc aataaggcta cccgagcctc
    18421 ttcaaaccag cggatataat tgctgtgatg aataatcccc atttgatctg tttcataata
    18481 aaaaggttct cgcacataac ctgtaaattt ctccatgact catgcctcgt tttccattga
    18541 ttttttacaa aaataattca tccacttcgg aagtgcttcg ctgatttgtg tcggcaaaac
    18601 aatatattgt tcttttgcca gctggtctcc aatgaaacta tgaagataaa cagctgctgc
    18661 aatcgtttgg tcattttgag gaaactgggc taaaaatcct gtgatcatcc cagctaaagt
    18721 gtcacccatg ccgcctgttg ccatagcagc agaacctaaa ggattggtgt agaagtgctg
    18781 gtgaccataa atttttgtct catgactttt caaaacgagc acagcaccga tttcctgttg
    18841 cttctttttg ttttctttat cccgttgttc ttgtatcggt agagaactca accgttgcca
    18901 ctccatttga tgaggtgtaa gtacagtttg ttcgggatag ggtagcaaaa gatgattagc
    18961 aacaagtaaa cttaaagcag agccatcaat caccagccat tgttcttttg attggttttc
    19021 tagtacttgt ttgaaacgtt ccaaactctt agaagaagta cccaatccgg gaccaatcaa
    19081 gagtacatct gcttgcttta ttacggaaag aaactggtca gtatccgtcc aatctacaat
    19141 cattgcttct ggcagatgac tgtgaagagc actccgattt ttttcatcag ttactacagt
    19201 cgtgagaccc gctccactgt gtacggcagc taaagcactc ataatgattg ctccgccata
    19261 ttgttcattg ccgccaatca aaacgatacg tccaaatgtt cctttatgtg aaatctttgg
    19321 acgaggtgtg atgactcttt tcactagttg ttcgtttatc agcatcgaaa aacctccttt
    19381 tactcattat agcgtatatt ttttttagag aaaaacagat aagaaaagga attgtcagat
    19441 tttttgaact atttttttct gtaatttgtg gtatcatgaa cacgaagact taaataagtg
    19501 gaggattaac tttatgacaa ttgattggca aaaagaagta gaagcacgta aagaagactt
    19561 gcttgaagac ttgaaaaatc ttttacgtgt caacagcgag cgcgatgatt caaaagtaac
    19621 accagatgca ccatttggac ctggacctcg cgacgcattg aaacatatgt tagcttatgg
    19681 cgaacgtgat ggatttaaag taaaaaatgt cgataactat gcagggcata ttgatcttgg
    19741 cgaaggagac gaaacgctag ggatatttgg acacatggat gtcgttcctg caggagatgg
    19801 ctgggacaca gatccttatg aaccagtaat caaggatgga aagatctttg cacgcggatc
    19861 aagcgatgac aaaggtccaa gtatggcagc ttactatgcg atgaagatca ttaaagaact
    19921 tgacttgaaa ctatcaaaaa aagttcgctt cgtagtcggc agcgatgaag aaagcggctg
    19981 gggcgatatg gcttattatt tcgaacatga agaagaacca gattttggtt tctcaccaga
    20041 tgctgaattc ccaatcatca atggtgaaaa aggaaatgtt tctttagctt tacgcttcaa
    20101 aggcgacaat gcaggagatt atgtcttgaa atcttttgtt tccggacttc gcgaaaatat
    20161 ggtgccagga acagcaactg cagcacttca agtaccaagt gcagatgcag ctatcgcgat
    20221 ggaagaagca ttttaccaat tcatcgaagc aaatccagta agcggaacga ttgaagcgga
    20281 caatacgtat gtaaaaatcg aattagttgg taaaggcgca catggtgcaa gcccacaatc
    20341 tggtatcaat gcaggttctt tcttggcatt gttcttagat aactatgaat tcctaggatc
    20401 tgctaaacaa tttatccatg tagcagctgc ttatgtccat gaagattttt atggagaaaa
    20461 actaggagtc gcttatgaag atgaaaaaat gggcaaattg acaatgaatg ctggactatt
    20521 tgcttttgaa gaaaatggta cagaggaagc gaacttcatc aatatgaatt tccgttttcc
    20581 aaaaggtgta acagtagacg gattgcaaag tgacatcgaa caaacagtgg ggcaagaagg
    20641 cgcaacagtt actcgaggtg ctcgcgtaat ggaaccacat tacgtaccaa tggatgatcc
    20701 attggtggct acattattgc aagtctatga agaccacact ggagaaaaag gctacgaaca
    20761 aatcatcggt ggcggaactt acggacgttt gttgaaacgt ggcgttgctt atggagcgat
    20821 gttcccagga tatactgata caatgcatca agcaaacgaa tttatgagtc ttgatgactt
    20881 gttcagagca acagcaatct atgcagatgc catctatcgt ttggcgaaat aaaaatacta
    20941 aaaaa
//
LOCUS       DADVXM010000043        19556 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.046, whole genome shotgun sequence.
ACCESSION   DADVXM010000043 DADVXM010000000
VERSION     DADVXM010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.046"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(152..316)
                     /locus_tag="KB927_001672"
     CDS             complement(152..316)
                     /locus_tag="KB927_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840591.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            611..1939
                     /locus_tag="KB927_001673"
     CDS             611..1939
                     /locus_tag="KB927_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBB6840592.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2141..2974
                     /locus_tag="KB927_001674"
     CDS             2141..2974
                     /locus_tag="KB927_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBB6840593.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2990..3727
                     /locus_tag="KB927_001675"
     CDS             2990..3727
                     /locus_tag="KB927_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBB6840594.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3882..4850)
                     /locus_tag="KB927_001676"
     CDS             complement(3882..4850)
                     /locus_tag="KB927_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBB6840595.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5082..5915
                     /locus_tag="KB927_001677"
     CDS             5082..5915
                     /locus_tag="KB927_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBB6840596.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5949..6788
                     /locus_tag="KB927_001678"
     CDS             5949..6788
                     /locus_tag="KB927_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6840597.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6814..7374
                     /locus_tag="KB927_001679"
     CDS             6814..7374
                     /locus_tag="KB927_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6840598.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7573..9294
                     /locus_tag="KB927_001680"
     CDS             7573..9294
                     /locus_tag="KB927_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBB6840599.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9459..10601
                     /locus_tag="KB927_001681"
     CDS             9459..10601
                     /locus_tag="KB927_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6840600.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10617..11828
                     /gene="thiI"
                     /locus_tag="KB927_001682"
     CDS             10617..11828
                     /gene="thiI"
                     /locus_tag="KB927_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBB6840601.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12401..13048
                     /locus_tag="KB927_001683"
     CDS             12401..13048
                     /locus_tag="KB927_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBB6840602.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    13177..13393
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13441..16086
                     /locus_tag="KB927_001684"
     CDS             13441..16086
                     /locus_tag="KB927_001684"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBB6840603.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16396..17709
                     /locus_tag="KB927_001685"
     CDS             16396..17709
                     /locus_tag="KB927_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBB6840604.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17699..18352
                     /locus_tag="KB927_001686"
     CDS             17699..18352
                     /locus_tag="KB927_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6840605.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18407..19099
                     /gene="radC"
                     /locus_tag="KB927_001687"
     CDS             18407..19099
                     /gene="radC"
                     /locus_tag="KB927_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBB6840606.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            19249..19449
                     /locus_tag="KB927_001688"
     CDS             19249..19449
                     /locus_tag="KB927_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6840607.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         6586 a         3300 c         4143 g         5527 t
ORIGIN      
        1 tcctactgcc ggagtaaata aagcttatgc aaagaaaaag aaatccaatc acttgggttt
       61 ctttttcttt tattattatg atgaatcaag ctttctgttt ttgtcacgta tgttgtaatc
      121 tttacgaaag agtagagttg gctactcata atcaaccata cttcccatca tcgctaaata
      181 cgaaataaat cagcattcct acaccaatca aagcacaagc tgcaccaaga aaagggatga
      241 cattcccaaa gttatctgta ttcataagta tgccaccacc cacaaacaaa aagccgccag
      301 caatcaggtt tttcatttta ttcatctcct ttcttacgtt atagtatttc cttctttcaa
      361 tgagtatttt gaaagctatc ttattgtatg atgttcttct aggcctcttc tttattatac
      421 aggccatttt cgttatctca tagaaatatt cctttttatc tgaaaactat tgtataccgt
      481 atgacatttt tcttcatgaa gttgtaagta tattctcatt caaatgaaaa tttcatcata
      541 gaagagattg tatttctaaa ttcttaagag taaaatacga agtataactt ggatttggaa
      601 ggatgattgg atgaaagcta ttacgcctga tatgacaaca aaatttaaca aacagtttca
      661 agcaaatatc aaacagcagg cattgcagcg ggcagttgtg aagaacggaa ttactgcttc
      721 tgctgaaaat gtttcagcac atgtggagaa tacaccggta ttttctatag atttggctac
      781 ggggaaagtg gctaatcaaa tgcaatcggg gcgttgctgg atgtttgctg cactgaacac
      841 attccgtcat aagatgctga atcaattcca tttaaaagag tttgaattat cacaaaatta
      901 cacttttttc tgggataaat atgaaaaggc aaattatttc tatgaaaaca tcattgcaac
      961 aggaaaagag gcaatcgata gccggaaagt agctttctta ctcgctactc ctcaacaaga
     1021 tggcggccaa tgggatatga tcgtttcatt attccaaaaa tatggcgttg tgcctaaatc
     1081 ggtgatgccg gaaagtgcga atagttcaaa ttctcgagat ttgaataact acttgaacaa
     1141 attactgcgt aaagatgcag tagtgttacg gaaaatggtt gctcaaggag aaacattaga
     1201 cgctattgaa gaaaagaaag aagaaatgct agaaagcatt tataacttct tagctatctc
     1261 attaggaaca cctccaaaag aattcgattt tgagtaccgc gatgaagaaa agaactatca
     1321 tcttgaccga ggactgacac cacaaatttt ttatgataaa tacatcggtg taaaattaga
     1381 tgattatgtt agcgtgatca atgcaccaac aaaagacaaa ccattcaatc gttcttatac
     1441 agtagagatg ctaggaaatg tcgttggcgg gaaagaagtc aaatatctga atgttgatat
     1501 ggaaactttc aaaaaattag cgattgctca gcttgaagaa ggagaatctg tttggtttgg
     1561 ttgtgatgta ggtcaatctt ctactagaac tagtggcatc atggccttag atgcttattc
     1621 aatggatgat ctatttgata cggattttac aatgactaaa gctgaacgtt tagattttgg
     1681 agaaagtctg atgacccatg cgatggtatt gaccggtgtt gacttagtag acgggcaatc
     1741 aacaaaatgg aaagtcgaaa atagctgggg cgaaaaagtt ggaaagaatg gcttctttgt
     1801 tatgagtgat gcctggatgg acgaatatac gtaccaaatc gttgtaagaa aagatttatt
     1861 gacgaaagag caattaaatg cgttcaatga agaaccaatt gttctatctc cgtgggatcc
     1921 aatgggtgct ttagcataga cgagtatttc aatgaagagt atgtagtaaa gataaaaaga
     1981 gctggcttaa gccagctctt tttatcttta aagtccattc cctgtttttt atggtccctg
     2041 tgctataatt ctaaataaag gataaggatt ggaaataatc cttttatcat taaaaatatg
     2101 atgacgaagt agaataaaat tgggagtagg ggggaaagtc atggatatcc aaactgtttt
     2161 atctgatctg aaattaaatg gtaaagtgat tccagttgtt ggtggcgatg ttaatcagac
     2221 ctatcgtata aaaaccgaac atcgtgctta ttttttaaaa atccatccga atgtaaaaaa
     2281 aggatttttt gaagcagaag tagacggatt aaaagaactg tcagcattcg tacgtgtacc
     2341 ggatacgtat atgctaggtg aaacaagtga aggcgcttat ttgttaatgg aatggatcga
     2401 gccgggaaaa ggggatcaac gagatcttgc tgcagcttta gctaatctcc atcagcaaac
     2461 agcgccacaa tttggttttc gtaaagataa ctatttgggt acacttgttc agaaaaattc
     2521 ttttgaagaa gattggtgga cttttttctt taaagatcgg cttgaatccc agatttcttt
     2581 ggcagaagaa acgaatcgat ggaatgtaca gcgtcaagaa aagtatctgc gatttaaaga
     2641 acgtgtattg aaatcggttg aaccaaaaaa gatcactcca cgcctcttgc acggagacct
     2701 gtggagtggt aatgtgttct ttgaccagca agggcatcca gtttttgtcg acccagctgt
     2761 ttcttatggg aatcgggaac aagatattgc aatgagccag ttattcggtg gtttccgacc
     2821 ggaattttta gatgcttatc aaactatatt tccattagaa aagggatgga aagaccgact
     2881 gccgatttac cagttatatt atcttttggc acatttgaat atgtttggag aaagttacgg
     2941 ttcccaagta gatcaattac tagaaaattt ttaagaggag ggcgtgtttt tggcaaaaaa
     3001 atataccaaa aagcatgaag tttcatatta tgagtgtgac atcaaccaaa cgatgacatt
     3061 tccttcgatg ttaggagtag ttatcaaaac gtctgaagat caaagcgacc agttgggaag
     3121 aggcagtgaa ttcgtcaata gctttggact tacttgggtc atcacgaatt attccatgga
     3181 gattaatcgt ctccctagag tcggtgaagt aatctcagta acgactcaag ccatggagta
     3241 caataagttt ttctgttatc ggaacttctg gatccatgat gaagatggga aagaattagt
     3301 caaaatagaa tctgttttcg tattgatgga ttttgtgaat cgaaaaatga gcagtgttaa
     3361 tgaagagatc attgctcctt ttgagagtga gaagatcaag aaaatcaagc gtcaggaaaa
     3421 aattgaaaag attgattcgg gcttcatgtt gccatatcgt gttcgttttt atgatatcga
     3481 tagtaatcag catgttaata atgcgatgta ttttaattgg atcattgacg tattaggata
     3541 tgactttttg actacgcatg ttccagaaaa agtaattatt cgatttgata aagaagtaga
     3601 gtacgggaat gagatcgaaa gccattttga acaaatccct atcgaaaatg gtgtcaaaac
     3661 aaaacatgaa atccgaatgc aagaacagct gtattgtgaa gcaaatatta tatggaaaaa
     3721 taaataaaaa agaggttgtg acagaagggg gcaacttcaa gaaataagaa gaaatttacg
     3781 aaaattgttt ctcaaatttt tgtaaatttt cgacttagtt ttcgaagaag ctatttttgt
     3841 cacagcctct ctttttaagt ttagctatta gataatgatg tttagttttg gataaacgaa
     3901 atcaattctt cacccgacaa accatagttt acagcaatca atagttttaa acgtgctttt
     3961 tgactattaa tactgttaca gaaaataatc cccatttttt ctagttcttt tcccccgcct
     4021 tcataatcat aaacaggctc tgcgattcca ttgaaacaac gagaaacaag tactacaggg
     4081 attttttgga caagaagctt ttccaaagca gctaaggctt gtggagggag attccccgca
     4141 cctaaagctt cgattaccaa accgtctact ttcgtatggg cgatggcttc caataagtcc
     4201 ccttgcatcc cagcatatgc tttaacgatc gggatagtcc catctacagc ggaaatgtcc
     4261 agtcgctttg tttctaaaag ttcctgcaag aataaaattc gattcttagt tactaagccg
     4321 atgggaccca atgtaggtgt tcggaaagta gcaacatttg tggtatgggt ctttgtcacg
     4381 tagcgtgcag aatggatctc atcgttcatg accaccaaaa cccccttatc tagcgcttct
     4441 tcacaacttg cgacacgaat cgcactttca aaattataaa ggccgtcact tccaagttca
     4501 ttacttgaac gcattgcccc agtcaaaaca attggtaatt tgttgccaat cgttgtatca
     4561 agaaaaaaag cagtttcttc taatgtatct gtaccgtgtg tgatcaccac tccggatata
     4621 cctgatgcat aagcggacaa gatacgttct tttaatacca acatgtgaga aggcatgatg
     4681 tgtggtgagg gaagattgaa gatatcttca actaataatt ctacatgctt ggggattgtg
     4741 atttctgcat ctaataatgg gtttgccaca tcaggactaa caccgcccgt gagcatgttt
     4801 tctttcatgg cgatcgttcc gccggtgtgt agtacaagta tttttttcat tttacagact
     4861 tccttacgaa taattttgca tagccgttaa atcttattgt atactatata aaagagtttt
     4921 gctatcagtg aagaataacg aatagcctaa cttatcataa aaaagctgac cttattaaaa
     4981 tggaaaagac tcaaccttga cctcctaata caatggagta tctggttgag tttcttttac
     5041 aagaaagcag ccaaggaaat caatcacgaa ggtggccgga aatgatcaga atcggattaa
     5101 catcgtttaa agaacatgac aaattaactg gtaaaaagaa taacactctt tatgaatatg
     5161 cagggtttct acccttagtg gaattagata ctgcctatta tggaattccc cgaaagtcct
     5221 cagttgagaa ttggataagt gaagtacctg aatcatttcg ctttgtagtc aaagtctatc
     5281 aaggaatcag cggtcaagga gactggaagc cttattatca gaccgaagaa gagatgattg
     5341 cgcatttttt agatgttatg tcgccaatgg tagatgctgg aaagatgttt tgctttttag
     5401 tccaattccc ctcatcattc aaatgtacga aagaaaatgt ccagtacttg cgcaaactta
     5461 gaaagtggtt tgagggttat cctgtttcta tagaattgcg ggattattct tggtacagcg
     5521 atgaatttct tgaacgtaca agaaacttta tgtctagagc cgctttttct ttagccatca
     5581 tcgatgagcc acagttgctg aatacaacga ttccttttga tccatttgtc accaatccga
     5641 actttgctct ttttcgattc catggtagga atgcgcaagg atggcaagca aatgataaag
     5701 agtggcgtaa aaaaagaacg ttatatcgtt attcagaaaa agaactgcaa gaactagcac
     5761 atgaagtcaa agtagttgat tctaagacaa aagaggtagg tgtgattttt aataataatt
     5821 ctggtggtga tgcggctgaa aatgcattag cactgcaaaa aatattaaat atcaagccag
     5881 atggactcaa tccaacccaa atggatctgt tttaagggct tattttattc aagaaagggg
     5941 cgaagtctat gatcaaagct attttttttg atattgacgg aacattggtc accaatcgtt
     6001 caaaagcgtt ggaatcaaca aaacaagcaa ttgaatatgc tcggaaaaac ggcattttat
     6061 gcggtgtagc aacggggcgc agcccagtaa agatcaaaga aatcattgat gaattggaat
     6121 tagatatgta tgtcgtgtat aatggtcaac tggtttttac tgcagatcgc acgattatcg
     6181 accacccttt tgaacaaaaa gtattggaac atattgttga atttgcagat gagaaccatc
     6241 gacaaatcgt ttttggtgcg agaaatcggt tagatggatc aacgacgatg ctattaggac
     6301 aatcgatttt tatcaagcga ctagtcagct ttttaccgcg taaattcccg gtacgtctga
     6361 tgaaaaaaat cctccaggtt tttagccctc accgacaaaa ggatcgttat gaaacgttag
     6421 agatattaaa agaaccaatt tatcaatgta tattgctcag tccggagtca gaacagaaaa
     6481 agttagaaca tcgctttccc gagtgtacgt ttcagcgttc aaatacgtat actgtagata
     6541 tcatcccaaa aggtggttca aaattactag gcatccaagc tttcgcaaat gctgtcgaaa
     6601 ttgaaatgga agaaattatg gcattcggcg atcattacaa tgatatcgag atgctgaaag
     6661 gtgtaggaat tggagtggcc atggggaatg ctcagatcga agtaaaacat gctgcagact
     6721 ttgtgactca atcaaatgaa gaagatggga tatacgaagg actgaaacac ttcggtctga
     6781 tttattagtc aatgaaagaa ggaaaaaatc agtatggaag cagagacacc ttttcaaaaa
     6841 gtagaaacat tccacaaaac ttttgatcca agaagaccag agatacccac ggcttttaca
     6901 gaaaatgaag ctcatacacg tgctgcgttc aaaatagaag aacttgttga atttgttgca
     6961 gctacttcac ctaataaaga acaactgcat gaagctgtta tgctgctgca cgaagcatta
     7021 gataaagcag aagaaaaaat acttggtaaa acacagtggg gaagtgatcc gctggttgaa
     7081 caagtagatg cactgacaga tatcctttac tttacttatg gttctttttc attactagga
     7141 atagtgcctg atcgaatatt cgaaatcgtc catcaggcaa atatggggaa attatttcca
     7201 gatggaaaac ctcattatga ccctgtaaca aataaagtgt tgaaacctga aaactggcag
     7261 atggaatatg ctccagaacc taaaatcgcg gcagaaatcc aacgtcagat tcaagaagcg
     7321 attgctaaga agaaatccgc tgatataggc atgtgcacaa atgaaaaaga gtgatcagag
     7381 tttcactatt tttgttatct ttatacgatg gaaaaacaaa agattttcgt ttaagttagt
     7441 gaatgcatga aaatagtatg ctataatcta gaatagatgt cttttgcacg agagacgtat
     7501 tatttggatt tatgccaagc agaacgccat ctgttgcata aaagatgcat actgaaaacg
     7561 gaggaaccat aaatgggaaa taatgttatc atcggaatcg tcattgcaat cattatagtc
     7621 gccattgtcg tctttttggt tagttacttg atgaagaaaa aaaaccaaga tcgattggat
     7681 gccttagaaa aacgcaagga agaattattt gacttgccag tgattgaaga agtcgatgat
     7741 gttaaaaaaa tgcatctggt tgggcaaagc caaaatacct ttcgtgaatg gagtcaaaaa
     7801 tggaatgaca tatctacttc ctcgttcgct gaactagaaa gtcaaatttt cgaagtggaa
     7861 aacctcaatg aaagttttcg gttcttaaaa ggaaaaaaag cagttgttga agcagaagct
     7921 acaatggacc aaatggagaa acaagtgacg gaaatccgtg aaggtctaaa ggaattgcgg
     7981 gaaacggaag aacgcaactc actagctgtt cagcaggcac ttgacgtcta tgaagaactg
     8041 aaagaaaaag tcagagaaga cgagcatgaa tacggaccag ctctttttga attgcaaaaa
     8101 cagatcaaag tgatcgaaaa agaatttacg cagtttgtga ctttaaacac ttctggagac
     8161 cctgttgaag cccgcgaggt tttggataaa gcagaaaaac atacgtatga agtggaagct
     8221 ctgatgaaaa aaattccacc gctgtatgag gagctccata ccactttccc tgaacaactt
     8281 gaagaaatca gtgatactta cgagaaattg atggaagaac aatatgtatt cccagaagaa
     8341 gatcttgctg aagatatcgc aaaagtaagt cgaagaattg aaaattcatt agccaatctt
     8401 gaaaaaacag aagttgaaac ggtcgaattt gaaaaccgtg aaacagctga tttgattgat
     8461 tcgttatatg atatcttaga acgggaaatg gaagctcaga gatatgtaaa aactaaccaa
     8521 tcaacgattg cagagtatat caaacataca acaaagaata accgtcaatt attgattgag
     8581 ctggatcaca catctcaaag ctatacattg aaccacaatg aaattggccg tgtacgaggt
     8641 ttccaaaccg aagtggaaga aatggaacgt caaaatgaac agatgattcc acagatccgt
     8701 caacacgaaa ttccttattc agaagtgcgc acgttctata aaacagtctt caaagtctta
     8761 gaagatatcg aaaagcaaca agtagagatc gacgactcat tacatgaatt gagaaaaggc
     8821 gaaaaagaag cgcaagaaaa gatcgataca ttcgaattca aattgcgcag tttgaaacgt
     8881 tttgtagaaa aacaacgttt gcctggcttg ccgaatgatt acctagaatt cttttttgtt
     8941 gctactgacc gtattgaaga actaagtgtt gtcttgaata aaattcgagt aaacatggaa
     9001 gaggtcaatc gtttagttgc tctatgtgaa gaagatctag aattattaga taagaagaca
     9061 catgatttag tagatgcagc agcattaacg gagcaaatgc tccaatatgc aaatcgttat
     9121 cgtcatacac acgaagaagt gagagaagca attgataaaa gctactattt attcaataaa
     9181 gaatatcact atcaagaagc attagacgaa atcggtacag cattagagcg agtagaacct
     9241 ggtgctttca aacgcatcga agatttttat tttaatcatc cagacttagt ataaagcaaa
     9301 aaagttagta aaccagcaag agcaagacgg attattgtct tgttcttgtc tttttttgta
     9361 tatttgaaaa ttgaaacaag tgaaaatttc acctgctctt gaaagcacct tggacaaccg
     9421 ttataataga aaagaatttc aaaaaagagg ggtttcttat gatatatttt gataacagtg
     9481 caacaacccc aatctttccg caaagcttag atgcatatgt aaaaaccagt cagcggatta
     9541 ttgggaatcc atcaagcttg catgatttag gcaatcaagc taaccggttg ttgcagcaag
     9601 caagaaagca gatcgctgat ttgatccatg tagaaccaga agaaatctat tttacttcag
     9661 gcggaacaga aggagataac tgggtattaa aaggaacgat gatcgaaaaa agagaatatg
     9721 ggaatcatat gatcatttca ggagtcgaac atccggccgt cagcgagaca gcagaacaat
     9781 taaaagaatt aggaatcgaa gtaagtatcg ccccagtgga taaacgcgga tttgtacgtg
     9841 tcgacgaatt gaaagaatta ataagaaaag agacagtatt agtctctgtt atggctgtga
     9901 ataatgaagt aggatcgatt cagcccatcc aggaaatcag tgatcttttg gatgattttc
     9961 ctaaaattca tttccatgta gatgctgttc aggcgattgg aaaagtacca ttctcgcaat
    10021 ggttgacaga aagagttgat tttgcaacat tttcagctca taaattccat ggcccacggg
    10081 gaactggttt catttattgg aaaaagggtc gtcgtttagc accattactg acaggtggag
    10141 ggcaagaaag aaatcagcga agtgggacag aaaatgttcc aggtattgtg gctatggtta
    10201 aagctttacg tttatcatta gagataaagg aacaaaaacc tgagcagaca caacgcttaa
    10261 aagtagctct aatcaatgcg ttgaagacgt atgagaaagt gacgattttt tcagaaggaa
    10321 ctgactatgc accgcatatt ttatgttttg ctctaaaagg aattcgcggc gaagttctcg
    10381 tccatgcctt agaagaaaaa caaatatttg tttctactac tagtgcctgc tcctcacgta
    10441 aacatatggc aagcagtaca ttgcacgcaa tgcatgtacc aaatgatctg gctacatctg
    10501 ctgttcgaat cagcttagat gaaaacaatt cgcttgcaga agtcgagcaa tttatgatta
    10561 ttttcaagca gctttataag aaattttctg caatcaatta aaagaggagt gttcttgtga
    10621 aatacagtga aattatggtc cgttatgggg aactttcgac aaaaggaaag aatcgaaaaa
    10681 gctttatcat gcaactagca caaaatgtca gacaagcttt gaaagacttt ccagaaatca
    10741 aaatccatgc tgatcgggac cggatgcatc ttttattgaa tggcgcagac gggcagctag
    10801 ttattccaaa actagcaaaa atatttggga tccaaaattt ctctccaagt attcgtgtag
    10861 aaaaagatgt cgaagttttg aaacaagctg ttcaagacat catgaaagaa atttatactg
    10921 ggaaagaaac atttaaaatt atcgctaaaa gaagcgatca ccaatttgaa ttgacaagta
    10981 atgaattgaa tcaaacatta ggtaatgctg tttttgatat tttcccgcat atccaagttc
    11041 aaatgcgtca accagatatt ccattacgtg tagagattcg gcgtgatggc gcttatctat
    11101 cgtatgaaac gatcaaggga gctggaggat tgcccgtagg aacaagcgga aaaggaatgc
    11161 ttatgctttc tggggggatt gattctcctg tagcagggta ctttgccatg aagcggggag
    11221 tggaaattga agctgttcat tttgctagtc cgccgtatac aagtgaacaa gcactgcaaa
    11281 aagcaaaaga tctaacagcc aaactagcac cttatgtggg aacgatccat tttatcgaag
    11341 tgccatttac cgagattcaa gaagaaatca aaaagtcagt gccacaagga tattggatga
    11401 caattactcg tcgaatgatg ttgcgtttga ccgatgaaat tcgccgtatt cgtcatggtt
    11461 tagtcatttt gaatggtgaa tcattaggtc aagtggcttc acaaactttg caaagtatgg
    11521 tggctatcaa tgaagtaacg aatacgccaa tcattcggcc tgtagcgaca atggataaac
    11581 ttgaaatcat tgaagtagca gaacagatcg atacatttaa tctttctatc cagccttttg
    11641 aagattgctg tacgattttt gctcctccac agccaaaaac acgccctcaa ctggaaaagg
    11701 tccatcaata tgaagagcgt ttagcaatag atgaaatgat ccaacgagca ctagctggct
    11761 tgaagatgga agagatacaa gcagaatcgt ctaatgaaaa aactgaagaa ttttcagaat
    11821 tgctataaga ggttatgaaa atagtgtttt gaccagagta ttagagaaac aaaacgaaaa
    11881 aatagctcca tgtattttac cgtttttgaa ctaatgtcga agattagctg attgaatacc
    11941 atttatcaag aagttatgga aaagccggtt cttttttact aactgaaaaa taaaatttta
    12001 tttagagatc aagctacagt tgataaatga tataaaaaag agaatttccc atgaaatagc
    12061 gaggttgtga cagaagtggg cagcttcaag aaataagaag gaatttacga aaattgcttt
    12121 tcaaattttt gtgaaatttc ggcttatttt tcgaagaagt tacttctgga acaccgtgta
    12181 tcagaggttg cgaaaaagct gccctgcatc aagtaataag aacagccaaa caaaaatagt
    12241 tcctcatatt ttacgtttgg ttgagcttat taccgcagat gcaagctttt gaacaccgtt
    12301 ttatttgtct cacacccttt tccttcctac ttgtaacctt gctcccgtgt tagaaacatg
    12361 ttacactaaa tatgtgaaat tattaacaag gagcgtcgtt atgcgagaaa aaacagatac
    12421 actgccaaaa gcaactgcga aaagattacc tttatattta cgctacttga agatgctgga
    12481 tgactcaggt ataagtagaa tcaaatcaaa tgagttcagc gaaatcaccc aaattccttc
    12541 tgcaacgatc cgcagagact tctcgcaatt aggcgagcta ggcagaagcg gatatggcta
    12601 tgatgtccct tttcttatcg atgtattcaa taatatcctt aatactaaag aagaaaaacg
    12661 aatcgcatta gtaggatatg gaaatcttgg caaagcattg aaacacaaca attttagaag
    12721 aaatgaaaat ctaaatatcg tgtgcgtctt tgataatgat ccagcactga tcaatcgagt
    12781 aattgatgga gaaatgatct atccgattga tcgtttcgcg gagatagcca aagcaaaaaa
    12841 tgtgacagta gcaatctcta cggtaccaag taaatattca caatctgcta ttgatgaaat
    12901 tgtcaaagga aatgtaaccg ctatacttaa ttttgcgcct gacagagtaa ctgtcccagc
    12961 ttatgtcaat gttcaataca ttgatttgac aaccgagttg cagacgctta tttactttga
    13021 tgagaattac tcagaagttt tttcttagga aaatttgagt aggcttattg atcttgcgag
    13081 aactcgtcgt aattctttca aaaatttttt agtactaaat gaagtggttt tttcacgacc
    13141 acttgttgac taaaaaaaaa aaccattgta gaatgaagca taacgctgaa caagaggagt
    13201 aactggcaca ttcattctta gagagagaac tatctgctga aaggttctca atgacaacca
    13261 gtgaaggtag cttgggagtt tctgtcttga atggagtaga gatagacgag tcgtgatcgt
    13321 taactcactt gagaggcaat aatgattgat tattgcaatt taggtggtac cgcgtaaatc
    13381 atacgtccta gaatacgaaa gtattttagg acgtttttta gtttaaagga ggaaaacagc
    13441 atgacggaag aaaataacct atcaacaaaa tataatccgc aagaagttga agctggacgt
    13501 tatcagcatt ggttagaaca agatttgttt aaaccgagcg gagataaaaa agcaaaacct
    13561 tattcaatcg taatcccgcc cccaaatgtt actggaaaac ttcatttagg gcatgcttgg
    13621 gatacgacct tgcaagatat gctgattcgt caaaagagaa tgcaaggata tgatacttta
    13681 tggctgcctg gtatggacca tgcaggaatc gcgacacaag caaaagtaga agcgaagctt
    13741 agagagcaag ggatttctcg ttatgatcta ggtcgtgaaa agttcatcga tcaagtgtgg
    13801 gaatggaaag aagagtatgc gagccacatc cgcgaacagt gggctaaaat gggcttatct
    13861 ttagattaca gtagggaacg ttttacatta gatgatggat tatctgaagc agtacgtaaa
    13921 gtttttgtta ccttatacga aaaaggtttg atttatcgtg gtgaatatat catcaactgg
    13981 gatcctcaag cacgaacagc tctatctgat atcgaagtta ttcataaaga tatcgaaggc
    14041 gccttttatc atatgagcta tgaactagca gatggatcag gcgtagtaga aattgcgaca
    14101 acccgtccag aaacgatgtt gggagatacg gcgattgctg ttcatccaga agacgagcgt
    14161 tatcaagcgc tcatcggcaa aaaagtgatt ctacctttag tcaataaaca aatcccaatc
    14221 attgcagatg aatatgtaga tatggaattc gggacaggtg tagtaaaaat cactccagca
    14281 catgatccaa acgactttga ggtaggtaat cgtcatgatc ttccacgcgt aaatgttatg
    14341 gatgatgatg gtacgatgaa tgaactagca ggaaaatatg ctggaatgga acgttttgct
    14401 gctcgtaaag caatcgtgca agatctgaaa gaaatcggtc gattgattaa aatcgatacg
    14461 atgatccaca gtgtgggtca ttccgagcgg acaggtgtcg ttgttgaacc tcggctgtct
    14521 actcaatggt ttgtaaaaat ggcgccgtta gcgaaaaaag ccattgataa ccaagaaaca
    14581 gatcaagcag tggaattctt ccctccaaga ttcaatcaaa cgtttttacg ttggatggaa
    14641 aatgtccatg attgggtaat ctcacgacaa ttatggtggg gacatcaaat tcctgcatgg
    14701 tatcacaaag aaacaggtga aatgtatgta gggatggaag caccagcgga tagtgaaaac
    14761 tgggtacaag atcctgatgt tttagacact tggtttagtt cagctttgtg gcctttctca
    14821 acaatgggct ggccagatac ggaaagcgaa gattataagc gatacttccc tactagcact
    14881 ttagtaaccg gttatgacat cattttcttc tgggtaagca gaatgatttt ccaaagcttg
    14941 gaatttactg gcgaacgtcc atttgagaat gtcttgattc atggattgat tcgtgacgaa
    15001 caagggcgga agatgagtaa atcattaggt aatggaatcg atccgatgga agtaatcgaa
    15061 aagtatggag cagatgctct ccgctggttc ttatcgaatg gttctgcacc aggacaagat
    15121 gtccgcttca gctatgaaaa aatggatgct tcttggaact ttatcaacaa aatctggaat
    15181 gcttcacgtt tcgttatcat gaatatcgaa ggaatgaccg tagaagagat cgatttatct
    15241 ggagaaaaat cagtggctga ccggtggatc cttactcgtt tgaatgaaac gatcgaacga
    15301 gtaactgagc tatttgatcg ttttgaattt ggtgaagcag gtcgacaact gtataacttt
    15361 atctgggatg atttttgtga ctggtacatc gaaatgagta aagaagtact ttatggagat
    15421 gatgctgttt caaaacaaac cacccgtagc atcttagtcc atacacttga tcagatccta
    15481 cgtttattgc atccaatcat gccattcgtt acagaagaaa tatgggaaca tattcctcat
    15541 cagggaaatt ctctagtagt ggcagaatat cctgttgtac gtccagagtt tgatgatgaa
    15601 acagcttcta aagggatgga agtattgaaa gaattgattc gagccgttcg aaatattcgt
    15661 tcagaagtga atacaccatt gtctaaacca attacgttgc taattaaaac aaacgatgct
    15721 aaaatcgatc aatttttagt tgaaaataca agctatatcg aacgcttctg taatcccgaa
    15781 gagttgacga tatcaagtga gatcactgcg ccagatctag cgatgtcagc tgttctgaca
    15841 ggtgcagaaa tcttcttgcc gttagcagga ttgatcaata ttgaagaaga aatcaaacga
    15901 ttagaaaaag aactggaaaa gtggacaagc gaagtaaaac gtgtccaagg aaaactttct
    15961 aatgaacgtt ttgtttctaa cgcgccggaa gaagtagtag aggcagagcg tgcaaaagaa
    16021 aaagattatt tagagaagca aacggctgtc aaagaacgaa tcgaaagttt gcgtactatt
    16081 caataagaat agaaaaagag agtgtgaaat cagctagcta ttactaaaag ctagctgatt
    16141 gaacatcgtt acaggaaaga gtttgagcct cactcttagc ttcgattcat aaggagatgt
    16201 gacataaatt ttgtcgcatc tcttttttag tctactctta ttatgtagga gaaggaggga
    16261 ggtggatcat gtatcaagag tcaataaagt agttgataaa atcgttcctc tctctgtttc
    16321 ttttctcttt gtcatacttt tatttttctt atgtgttcta tttgttataa taaaagagaa
    16381 atgggggaat tgttgatgac gattgaagaa gcaatagaat ggatccatag tcgattacca
    16441 tttggttcac gtcctggcct tgaccgagtc gaagctttat tagaagtggt agggcatcca
    16501 gagagaaaag taaaaacgat ccatatcgct ggaacaaacg gaaaaggttc tactgtagct
    16561 tatttgagaa gcctattaga agaggctggg ctgacagtag gtacatttac ttcaccttat
    16621 atcgaaacgt tcaatgaacg gatcgcaatc aatggcaaaa gcattccaga caatgatttg
    16681 atccagcttg taaaaaaata tcagccactg atcaaacaac ttgatcaatt tgaagcagta
    16741 gctggtatta ctgaattcga gacattaaca gcaatggcat ttgattattt tttgatgaag
    16801 aaagtggacg tagcgattat cgaagttggc ttaggcggct tattggattc taccaatgta
    16861 gctgtaccaa tgctgacggg aataacaacg attggacttg atcataccga aatacttgga
    16921 gatacaattg aagaaatcgc tgcacaaaaa gctggaatca tcaaacaagg cgttccagta
    16981 gtaacaggaa atattgcccc agaagctttt actgtcatcc aacaaacagc taaagcaaaa
    17041 aatgcaccgc tttatgtata cggggaaaat tataaaataa actatctgca tcctgatgag
    17101 atgtggggag aagtatttga attttttaat gaaataggaa agatccctca attaaccact
    17161 ccgcttttag ggcaacatca agctgaaaat gcaggagtag ccatcgaatt gtattttgtt
    17221 tactgtcaat tggaaaagct gcctttccga gaaaaagatg ttttgaaggg attgaagaaa
    17281 tctcgatggc caggaagaat ggagcgtttg agtaacgagc cattagttgt tttagatggt
    17341 gcccataata cgcatgcaat gaaccggctt gttgagaatt tgaaaaaaga attcaaagga
    17401 tatcaaatca acattttgtt ttccgcctta cgaactaaaa atgttagaga aatgctagaa
    17461 cgattgcagc aagtaccaaa tgtccatatt tatttgacga cctttgaaca tccaaaagcc
    17521 atcgaattaa gtgaagtatc agatttagca agtgagagag tatcaatcgt ttcattgtgg
    17581 caattcggat tagcagatat attggaaaag atgacaaatg aagacgtatt agttgtgacc
    17641 ggttcacttt atttcatttc agaagttcgc catttattaa tacaattagg aggagatcat
    17701 gaagtataat gcagtgattt ttgacatgga tggtttgctg ttcgacacag agttagtgta
    17761 ttacgaagcc acacaagtag tagcagacaa gatgggtttt ccttatgata aagacctgta
    17821 tttaaaattc ttaggtgttt cagatgaaga agtatgggcg aattatcata tgattttctc
    17881 ggaatttggc aaaacaagtg tacaaagatt catagatgat tcataccagg aaacgcttga
    17941 acgtttttcg caaggagcgg tacaaatgaa gcccggtgtg ttggaactcc tctctttttt
    18001 agaagaacat cagattccca aagttgtcgc ttccagtaac caacgagcag tcattgaact
    18061 tttattgaag aagaacaatc tgtttgaacg atttgagacg attgtttctg cagaaaatgt
    18121 tcaacgagca aaaccagacc cagaaatttt cttgttagct aatcagaagc taggtacagc
    18181 gaagaaagaa acattgattt tagaagattc acaaaatggt attttagcag cttctgcggc
    18241 tgagatcccg gtagtcatgg taccagatct gcttccacca tcccaagaat tgatcaaaaa
    18301 aacagctggg gttgtttctt ctttacatga aatccctgca ttgttaaaat aaaaatccat
    18361 ctcttttcgt atcttatttt agataagata gaaaggagat gtttttttgg gaaaacgatt
    18421 gatcaaagaa gtacctacta gctctttacc aagggaacgt atggaaattt atggcgcgga
    18481 agctttatcg gatcaggagc ttttggcaat cttactgcgt accggtcaac acccttatag
    18541 tgtgatgtcg attgctggaa atctgttaaa aacgtttgga ggactggcct ctttacgaca
    18601 ggctactttg catgagttag aagagattcg agggatagga cgcgtgaaag caatcgaaat
    18661 caaagccttg atcgaattag gtcgacgaat tcagacggat catgaaagag cggctccacc
    18721 ggttcgtacc agctacgaat tggcccagca attgattctg gaaatgaaag atcacaaaca
    18781 agaacatttg gtttgtattt atttggacac gaagaatcaa gtgatcttaa aaaaaacagt
    18841 gttcatcggt tcgctgaatc agtcagtcgc tcatcctaga gaaattttcc attatgctgt
    18901 acgttattgt gcagcaagga tcgttttagc gcataatcat ccttctggta atgttattcc
    18961 atcgcagcag gatatgaatt ttaccaaaag gatacaaaag tgtggagaaa tgatggggat
    19021 cactgtactg gaccacttga tcatcggacg caaacgatat tttagtttga gagaagaagg
    19081 aatgatggaa gagaagtaag ttgctttctt gcaaaaaaaa tgaagcaagt gtacaattat
    19141 attgtaattt tgtttgggaa tagaagttga aacatctgtt gcacctctat cgtacacgag
    19201 caatgttaca atttaaatta gtgcttttgg cacgaggagg atattattat ggaaaacgga
    19261 acagtaaaat ggttcaacgc tgaaaaagga tttggattta tctcacgtga agatggaagc
    19321 gacgtattcg ttcacttctc agctatccaa ggtgacggat tcaaaacatt agaagaaggt
    19381 caagcagtga ctttcgacgt tgaagaatca gaccgcggcc cacaagctgc aaacgttgta
    19441 aaagcttaat tttatctgta aatcaaattg atggtagaca tcaattttta cgagagaaca
    19501 aagcgagtaa caaaaatacc tgccacaaga gacaatttct cttgtggcag gtattt
//
LOCUS       DADVXM010000044        19546 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.047, whole genome shotgun sequence.
ACCESSION   DADVXM010000044 DADVXM010000000
VERSION     DADVXM010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.047"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            1030..2280
                     /locus_tag="KB927_001689"
     CDS             1030..2280
                     /locus_tag="KB927_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBB6840608.1"
                     /translation="MKKQYNIAVAGTGYVGLSIATLLAQHHKVTAVDIIPEKVELINN
                     RKSPIQDDYIEKYLAEKELNLTATLDAKAAYQSADFVVIAAPTNYNSRTQHFDTSAVE
                     AVIRLVMEVNPDAIMVIKSTIPVGYTASVRVKTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMDDERLVEDAHTFATLLQEGAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPENLIEAIVESNRTRKDFIADRVLQMAGYYNYAEANQYDAGKEKPVVIGVYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPTLKDGETFFGSKVVNDLEQFKAMCDSVI
                     ANRYDACLDDIKEKVYTRDIFQRD"
     gene            2299..3309
                     /locus_tag="KB927_001690"
     CDS             2299..3309
                     /locus_tag="KB927_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBB6840609.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFKENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSAELSYSRTERVTSIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALEGKYADKKKLADEAIYLERVLCNEAGGWQDQIAASYGGFNRI
                     NFNVDGYEVLPVIISPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAILTDKNRNLDDFGRQLDVTWRLKKGTGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQDAVRWAMRDLMYIPFEFENGGTRVIHYTPETYIEKQ
                     NG"
     gene            3319..3972
                     /locus_tag="KB927_001691"
     CDS             3319..3972
                     /locus_tag="KB927_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6840610.1"
                     /translation="MLAEKLNKHIDLLIKRYPTLETIKQDIIDGYLIMEECYLNGGKL
                     LVAGNGGSAADSEHIAGELMKRFKTPRPVSKEFADKLVAIDPVRGPELAKNLECGLTA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRSGDVFLGISTSGNSKNIMSATVVARA
                     LGIKVIGLTGAKGGELATVADVCVKAPEVETYMIQEYHLPIYHCWCLMLEDKFFGNE"
     gene            3991..4989
                     /locus_tag="KB927_001692"
     CDS             3991..4989
                     /locus_tag="KB927_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBB6840611.1"
                     /translation="MKKTIMVTGGCGMIGSNLVKRLVKEGCWDVYVADNLWRGKLEYL
                     NDEDGHPVIDLDTHFFNADLTDYEQAKKVIGTTEYVVHLADVVAGIDYVFKNQGELFR
                     INNLINSNVFDCCRKAGKEKIKGVIYVGTVCSFPLTRQNTLNPEPLREEELFPALPES
                     AYGWSKLMGQLEMGYLEKETGIPCCILMLHNVYGTPTDFGERSQVIPALIRKAINNPE
                     EPFNVWGSGEQGRAFIHVNDIVNALVLALDKGWGHGHIQIGPSHCTSIKEIAYKIIEI
                     SGKDIKPFFDTSKPEGDKARCADYSKAKEILDWEPTVSLEEGLRESYNWIEKQIKG"
     gene            5065..5826
                     /locus_tag="KB927_001693"
     CDS             5065..5826
                     /locus_tag="KB927_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HBB6840612.1"
                     /translation="MEKNMYKRKRDFTVCGIVGVCATTKNEFVREVFSMPTSPVSATV
                     DLVGVPAIISAKENPKIAEMYSQATMAAIDGMPIVKIGRRKGFTCERCAAPDIMGMVF
                     EEGVRQGKTHYFYGGKDNEVLNKLRANLERDYPGIKIVGMYSPPFRPLNEEEDSKICE
                     EINNLNPDFLWVGIGAPKQEMWMWEHQKKIHNTVMFGVGAGFNFFAGTLEKAPEWMEK
                     ASLEWLFRLVKEPRRLWRRYILGGIKYIYYTIESK"
     gene            5844..6950
                     /locus_tag="KB927_001694"
     CDS             5844..6950
                     /locus_tag="KB927_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6840613.1"
                     /translation="MKILIVVTMTNNFGKKGSYNSQEIGLARGLAELGHEVIVYKSVK
                     SDEEVGTEQLSNTAMIHYIKCRYVGSNGFLSTKNFDKNADVLIQFADLQLSVPHVYSW
                     TVKNGIKYIPYNGITRSQSGNKYIKTIIEILAHRNYKIYKKNGCVAKNDRVSEKLVQL
                     GVNKVKLAPVCVDFEQLHKNYEAIDFTTLREKWNIPRNVRVILYVGRFEKDKRPLDMI
                     SLFNKLDEHNYLLMVGTGALLEQTKQQINLLGLQNRVKIIERIPNKDIWELYCLSDVF
                     VNLNYTEIWGMVLLEAMYYRLGIIAVNAPGPQNIILDNRYGMLAKSDDEILTFLKDGR
                     FTNDIIDAAYQRVTTEFRWSKSGEIMLSMLEGDK"
     gene            6940..7173
                     /locus_tag="KB927_001695"
     CDS             6940..7173
                     /locus_tag="KB927_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840614.1"
                     /translation="MINDMEVTKLMALRNRYALNIVDNCTRKIAKILGCCIGKGAQIG
                     NSVEFVHNSVGTVIHSDTILEDGVKVYQNVTCG"
     gene            7372..7827
                     /locus_tag="KB927_001696"
     CDS             7372..7827
                     /locus_tag="KB927_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine acetyltransferase"
                     /protein_id="HBB6840615.1"
                     /translation="MNAYKLYKVERWFYLHKMEFFAKIVKALIYVLHNSSISYQTEIG
                     DNCKFLYGGIGCVIGKDTKIGNHVIIGTNVLTGGRSNKPGMPTIGNNVYIATGAKILG
                     NITIGDNVIVGANAVVINDVEPNCSVGGVPARVLKKDIDVNDYCSLNRY"
     gene            7841..8614
                     /locus_tag="KB927_001697"
     CDS             7841..8614
                     /locus_tag="KB927_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6840616.1"
                     /translation="MLYFVIPLMSAKAANNWEMVSTLFNRTLWSCYNQTDPDFKIIVA
                     CHEIPKLTHEYDDRVEFIQVSEKDAPIPTNQDEKMIDKGYKTHALAMRLRELGGGFAM
                     MVDADDLVSSHLAEYVNSHPQENGFYVKTGYVYFVGDDYMKVLPKFSSGSACIVKYAV
                     EDLPEAYPEVMTANCDDNPWIIRKRHGGVVPACEEQGRPLKPLPFKAAVYVLGTGDNH
                     SLYGKTTKYQTKMREILEMFIAKRKIKGKLKAEFSVDWL"
     gene            8601..9731
                     /locus_tag="KB927_001698"
     CDS             8601..9731
                     /locus_tag="KB927_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6840617.1"
                     /translation="MIGYKVSIMKVLMCESQMPENWYSFDLSKELNQYVDLTLLCKRD
                     VPPLDPKIKSKHILYHKSTNKVFSALVFLKSLFLIWKEIRFGDYDIVHLQLMKSLKYE
                     GGLYVLCKRHYKKLIMTVHNVLPHEVREKDRQEHFNIYSNCDGFIVHNRVTEQHLYAE
                     FPELNAKSYVCPHAIYGDVKHISRAYDKDKFEFILFGQIRPYKGIDVLLNAITELPMD
                     VRKKVHFTIAGQQHPKQDSTDYKKMIEDLKVSDCVLYKPERISDEEMDSMFRNADAAI
                     FPYKEIYGSGALLMAYTYCLPTIVSNVPAFMEETEEGKIGLLFENLNSKSLADTIVKY
                     VNLSPAEKSKIEDDIYELVNRKYTWAASAKLTYEAYKQILNE"
     gene            9762..10997
                     /locus_tag="KB927_001699"
     CDS             9762..10997
                     /locus_tag="KB927_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840618.1"
                     /translation="MQISKWKIIQFLMVFLMIISSSILKPLGGWLGETMNVRLVTVIL
                     AIVCLLIASLPAFRKNRYLNFCTLLICVVIIAAYIYSDKTIWVKSRESMSLYYVLLAY
                     PLFCTLINQAWNLDSMLNTICGVTFLSYILRTSISLIQKFSGVLLYENIYRECAPENW
                     YRGGFLRINPPCFTIIIIPIALYMIERQVVARRKVKYYLLIASALAYSAVIHGSRSVL
                     VYQIIVLGCYILFKKGSSKRKIAMWVLAGLLVVIFINSTMFSTFVETFTNSTGEYAGS
                     AESRFASVWFFIPKFLQSPLFGTGILTGEEFTFILPGGVRGHLSDIGFFYTITQYGVG
                     ILIFDILFIIKGFKTALLASKVGMTGYQYLAFGITLNVLLTGINIDWFYPIFTPAIPV
                     CLAVIEYIYQECRSVANIE"
     gene            11022..12131
                     /locus_tag="KB927_001700"
     CDS             11022..12131
                     /locus_tag="KB927_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840619.1"
                     /translation="MNKKEILYNILKKYENLPYVFRNMFGHNISKLVSWKLTADCATV
                     EENSEVYAAFQLRSKDMSDVPVMGLVNCCKDVAIVMQGPLCLKDDFSYNTLAYYKKCY
                     PNALIILSTWKDEDIKALKRIEDLGVIVICSEKPEKPGHLNINYQVGNTLPGIVRAKQ
                     LGAKYVCKTRTDQRIYHPNAMAFFCSLLEQYPVNNEDDWKLIQNQRLLLLSMPYGDMF
                     FPYCLSDFLYFGDVDDMINLFSIPSDVREKGAVSRGVSRREISENNLAPEVQLLRSYI
                     SRMGGNEECSIRAYWEFVKNHVITINKNQIDLYWHKYVGRYSNNTIYGTYYIDDSQDA
                     LHCYNFDFINWLNLYTGKYEYKAEYEKYMDFVWEE"
     gene            12173..13507
                     /gene="gmhB"
                     /locus_tag="KB927_001701"
     CDS             12173..13507
                     /gene="gmhB"
                     /locus_tag="KB927_001701"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HBB6840620.1"
                     /translation="MKTVIMAGGRGSRISELFPDIPKPMIPIDGIPVLERELCSLRDQ
                     GFNDIILTVSYLHEKIEEHFGDGSKLGIKIKYFIEKTPLGNAGALYFLLDELGDEPFL
                     LLNADAVFDVDFRQMIRFHVENNADVTLFTHPNSHPYDSGLIISDDNKKVLQWLAKED
                     QRPEYYKNRVNAGLHVINPKVLRENPLMEIVNKSIVEGGGLPYKIDLDRMILKPLANT
                     GRMYCYDSPEYVKDMGTPDRYRAVIKDFQKGIIVGKNLSNPQKAIFLDRDGTINKYVG
                     FLRNAEEFELIDGVSEAIKIINSLGFLCIVITNQPVIARGEVTVDELNSIHNKLETML
                     GHAGGFLNGIYYCPHHPHKGYAGEVIELKIDCNCRKPKPGLLLEASKDFNINLSQSFM
                     VGDSESDVIAGKNAGCKTVLITEDITLPANYGQDYSVCSLLEFVKNHLCTMQ"
     gene            13542..15179
                     /locus_tag="KB927_001702"
     CDS             13542..15179
                     /locus_tag="KB927_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HBB6840621.1"
                     /translation="MKVLIPAAKVVEKELQSIGMLPAIIYPINKKIVFDYLYNQYNAI
                     CDSLDIICYEKADKVHRRLKNYHDSRIHICDLPELGDLGQTVYFGLSDEDEPVLINFA
                     DTIVMESMSDIEMDTFYYSEDFVSSTWTYFKINEGIITDIHDKEEAYVSDKREKLFIG
                     VFMFSSSKLLKSCLREAVESRKQGGINSFYRALQLYSERCPLKAVRTEKWFDIGHIDK
                     YYNTKLEVKAREFNHISIDKDRGILKKTSDDKDKFIGEIKWYLKLPADIEYVRPRIFD
                     YSTSYVAPYVDMEYYAYHTVHELYLYGDLKYNQWHDLFSRIKFICSDFKRYTLKDEKI
                     RESLEDMYLRKTMQRFQKLSEDKRFSAFFEKQIQINGRKFISLTGVIELLKNLIPSML
                     YDVNEFCIIHGDLCFANMMVDSNCSFVKVIDPRGKFGKYDIYGDSRYELAKLFHSLDG
                     KYDYIIKDLFTVEYDTECAVIDYTINTRVRDYDLFELFKSVFSDEIKDDFDKIVLIEA
                     LLFLSMIPLHGESFDHQIVMLATGMELLARVSNKVIL"
     gene            15281..15676
                     /locus_tag="KB927_001703"
     CDS             15281..15676
                     /locus_tag="KB927_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HBB6840622.1"
                     /translation="MYSEYSFVFDIDGTLCPIKKKDERYEDLVPYENMVEKLRFYKEN
                     GAKITLFTSRNVNSYKGNLGMINANTAKVLLAWLDKWDIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLRCSVDELNEICNSSKKRF"
     gene            15694..16425
                     /locus_tag="KB927_001704"
     CDS             15694..16425
                     /locus_tag="KB927_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6840623.1"
                     /translation="MEKKMTVIITMAGLGSRFRKIGYAVPKYMINAKGRTLFDWAMDS
                     LVGYNKNVDKYIFVVRQEDNASAFIKEHCAYFGIENVEVIEIDYMTDGQATTCMLAIP
                     YCNQDNEIMVYNIDTYVESNEMKYEDICGDGHIPCFHADGDHWSFAKLNDRNEVIEVR
                     EKVRISDNCTLGAYYFSSAKLYKALYEEYYADSSNMEKNEKYIAPLYNFMIKKGLKVT
                     ISIVDAKKVHVLGTPEELNVFLNQE"
     gene            16449..17900
                     /locus_tag="KB927_001705"
     CDS             16449..17900
                     /locus_tag="KB927_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBB6840624.1"
                     /translation="MTSNNLIVKTLSRYKNTPLPVKAALWFMVCGFLQRGVSMITTPI
                     FTRVLSTEQYGLYSTYLSWESLLLMITSLSLFKAMMNLYVKYDNQEHILSTVSGLTLV
                     LTIFWFVIAIFIKDILAEILGLTPVLVVCMFSYFIFQAEIQCWSLHKRYIYDYKTLLV
                     ATLAVTVGSSVVGCLAVLFISPTAEARALMNVLVTGVVGVAVYISVFRRCKDFKDNEV
                     WNFAVVFCVSLMPHYLSEFILNGSDKIMINYLCGSSDVAIYSVAYSIGALINLVTNSV
                     NSTFAPYQYQKIKSGEYDLLSKRANEVLGLVAAMLFALMLFSKEIVLIFGGQKYIDSV
                     NLIVPICIGIYFNYMFQLFARVQEYFEKKLTVVIPSVLCAIMNIVLNYVFIKLYGYQA
                     VAYTTVFSYMFFCVIHYIFYRKVCKELLDGKNIYDVRGILLISAITIAGGILISIINK
                     FDFIKYLIIAIACVAAIIFRKRLLLLVRRIMSK"
     gene            17926..18537
                     /locus_tag="KB927_001706"
     CDS             17926..18537
                     /locus_tag="KB927_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBB6840625.1"
                     /translation="MIDIISAITVNVLTALYQPFLFAVLTAYLFMYWYLFIVDNSRDP
                     KNLKDSVLIWLRYFKASSKFRRLFFLAFYFTLILFKTLLNRNMWMNPLSNVIGQWSLY
                     IIDNATGESRLTTECVENTMLFIPFCMLLLWWRDIKCDIIRTIYVGIKYVFLFSLSIE
                     FTQLFFRLGTFQLSDLFYNTLGGLIGALLYWLFYRLNKYIDLK"
     gene            18719..19234
                     /locus_tag="KB927_001707"
     CDS             18719..19234
                     /locus_tag="KB927_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HBB6840626.1"
                     /translation="MVVVMVKVFDIIKFSDFRGYTAVALDNETLFSIGIEFHIKQINQ
                     GFSHNKYTMRGLHYQSGEHAQGKIVMCLHGEIMNIALDIRQGSSTYGCVYVNTLSESN
                     GKCAYIPRGYAHGYLTMEDNTLVQWCVDNDFNSNAAKCISYESVDIEWPVSRQCFVIS
                     EKDKNVERLSF"
     gene            complement(19369..>19546)
                     /locus_tag="KB927_001708"
     CDS             complement(19369..>19546)
                     /locus_tag="KB927_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBB6840627.1"
                     /translation="KTVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRA
                     QRRFEGTLRYSLGY"
BASE COUNT         6308 a         2742 c         4250 g         6246 t
ORIGIN      
        1 ttggaggtat agaaacagtt atcattttat ctttgtacca ccaatgattt atatcagctc
       61 aacagagtga attgtattta cgcaagaatg cgtaggatga aatggataga taattaagat
      121 atatatgtat atggtgactg aagacaaaaa aacagaacta atgaaactga ataaaaatat
      181 agagtgaact agtttctaag agggatttta aactagattt cattggtaat aaaatttgga
      241 cagatggaaa aacatcacat aaggaagcag attttgttgt catttttgtt cctacaaact
      301 atggtagtga atgtgttatt gaattagtga tgtctgttac ttcagaggca ttggggataa
      361 ttaaatccac tatacctgta ggatatacaa aaagtggaag aaaaaaatat tatcaataga
      421 ttttatttag ttcagaattt ttacgtgaaa gtagattatt aatgataatc tttatccaat
      481 tagaattatt atcgtaggat gtgatgatga aagccgtgaa attgttcaag tatttaccaa
      541 tgtctccctg ccagtaaatc cgcttagaat ttgagccttg aaaatgtgca atgataaaaa
      601 acaaaaactc gctcaaaata gacagtttgg ggtgggaata gaccaataat gtaccaaaca
      661 aacttccatt tggggtgaaa ataggtcaat aaagcgatgt taaacatacc tttggagtaa
      721 gaatagaggg taataagtga atttataaac tttttggtga ctggttgagt ggaaaatgta
      781 ggtacatttc aatgcgaaaa tgtattataa ccccaaacga ggtcaataaa aatgactcaa
      841 acttgcaata taaccctaaa cgggtagggg atttatgaaa aattgaattt gccggcgtag
      901 gagctggctg ttttaagtat gaatgaacac agctttcggg ctgttttata taaatagcag
      961 gttactgttc acaaacagca ttttgttaag aaagtagtga ccacagcagt ggtggaaaga
     1021 ggaaatatta tgaagaaaca gtataacatt gcagtcgccg gcaccggtta tgttggtttg
     1081 agtattgcca ctctgttggc acagcaccat aaggttacag cggtggatat cattccagag
     1141 aaggttgaac tgattaataa ccgtaaatct ccaatccagg atgattatat tgaaaagtac
     1201 ttggctgaga aagaactgaa tctgaccgca acattggatg caaaggcagc ataccagtct
     1261 gcggattttg ttgttattgc ggctcctact aactacaata gccgcactca acattttgac
     1321 acatccgctg ttgaggctgt tattaggctg gtcatggaag taaatcctga tgccattatg
     1381 gttattaagt ccaccattcc tgttggatac accgcttctg ttcgtgtaaa gactggtagc
     1441 aagaatatta ttttcagccc tgagttcctg cgtgaaagta aggcactgta tgacaatctg
     1501 tatccttcgc gtattattgt gggtaccgat atggatgatg agcgtttggt tgaggatgca
     1561 cacacttttg ctacactgct acaggaaggc gcaatcaaag agaatgtgga cacattgttc
     1621 atgggcttta ctgaagcaga agctgttaag ctgtttgcca atacatatct ggctcttcgt
     1681 gtcagctact tcaatgagct ggacacttat gcagagatga aaggcttgaa cactcagcag
     1741 atcattaatg gagtttgcct tgatcctcgt attggtactc attacaacaa cccttccttt
     1801 ggttacggtg gctattgcct gccgaaggat accaagcagc ttctggccaa ctacgcagat
     1861 gttcctgaaa atctgatcga ggcaatcgtt gaatctaacc gtactcgtaa ggactttatt
     1921 gcggatcgtg tacttcagat ggctggttat tacaattacg cagaagcaaa tcagtatgat
     1981 gctggcaaag aaaagcctgt tgtgattggt gtttaccgtt tgaccatgaa atccaattct
     2041 gataacttcc gccagagttc tatccagggc gttatgaagc gtgtaaaagc taaaggtgca
     2101 actgttgtga tttatgagcc gaccttgaaa gatggagaga ctttctttgg cagtaaggtt
     2161 gtgaatgatt tggaacagtt taaggcaatg tgtgattctg ttatagcaaa tcgctacgat
     2221 gcttgccttg atgacattaa ggaaaaagta tatacccgtg atatcttcca gagagactaa
     2281 gattaggaga gagtatttat gattattaca aaaacaccgt ttcgtatgtc tttttttggc
     2341 ggtggaacgg atatggagga ttatttcaaa gagaatggcg gtgcagttct ttctactact
     2401 tttgataagt actgttatgt gaatgtgaga catctgccta gattttttga ttacagcgct
     2461 gagttatctt attctcgtac tgagagagta actagcattg aagatattga gcatcctgcg
     2521 attcgtaatg cgatgaaaat gctcgatatg catgaaattc ggcttacata cgaagctgat
     2581 ttacctgctc gctctggtct gggtacatcc agttcttttg cagttggtat gttgaatgct
     2641 ttttatgcac tggagggtaa gtatgctgac aagaagaaac ttgctgatga agccatttat
     2701 cttgaaagag ttctgtgtaa tgaagccggt ggatggcagg atcagattgc cgcatcttat
     2761 ggtgggttca atcgaattaa tttcaatgtg gatggttatg aggtgctgcc tgtcattatt
     2821 tcgcctgaac gtaaaaagca gcttaacaac aatctgatga tgttctttac cggattcact
     2881 agattttctt ctgatgttca aaaggctaac aacgtcagtg gcacagagga taagagagta
     2941 agactgaaaa agatgtatga gcttgtagat gaagctgagg caattcttac tgataagaac
     3001 agaaatttag atgatttcgg tagacagctt gatgttactt ggagattgaa aaaaggtact
     3061 ggtggagcaa ttagtacagg aagcattgat gaactatatg aaaagggtat ggctgcaggt
     3121 gctttaggcg gaaagttgct cggtgcaggt ggtggaggtt tcttggtttt ctatgtacaa
     3181 cctgagaaac aggatgcagt tcgttgggct atgcgtgatt tgatgtatat tccgtttgaa
     3241 tttgaaaatg gtggaactag agttattcac tacacgccgg aaacttatat tgaaaaacag
     3301 aatggataag gagtaacaat gttagcggaa aaacttaata aacatattga cttattgatt
     3361 aaacgatatc ctacacttga gacgattaaa caggacatta tcgatggata cctaattatg
     3421 gaggaatgct atttgaatgg tggtaaactt cttgtggcag gaaacggagg atcagccgct
     3481 gactcggaac atattgctgg cgagttgatg aagcggttta agacgccacg tcctgtaagt
     3541 aaggaatttg ccgataagtt agttgcaatt gaccctgtaa gaggtccgga attagccaaa
     3601 aatctcgagt gtggtttaac ggcaattcct ttggtcgcac acgaagcatt gtctactgct
     3661 tatattaatg atgtcgatgg tttgggtgtc ttcgcacagc agctgtttgg ctttggtaga
     3721 tctggtgacg tattccttgg tatttcgacg tccggaaata gcaagaatat tatgagcgca
     3781 actgttgttg ctagggctct cggtataaaa gttattggct tgacgggcgc aaagggtggg
     3841 gaacttgcca cggtagcaga tgtttgtgtt aaggctcctg aagttgaaac atacatgatt
     3901 caagagtatc acttgccgat atatcattgt tggtgtttga tgctggaaga taaattcttt
     3961 ggaaacgaat aaaatttgga ggaatgttaa atgaaaaaga caattatggt taccggtggt
     4021 tgcggtatga ttggctccaa tcttgttaag agactggtga aggaaggctg ctgggatgtt
     4081 tatgtagctg ataatctgtg gagaggaaag ttggagtacc tgaacgacga agatgggcat
     4141 cctgtcatcg acctggatac tcatttcttc aatgctgatc tgactgatta tgagcaggct
     4201 aaaaaggtta ttggtacgac tgagtatgta gttcatctgg ctgatgttgt ggctggcatt
     4261 gactatgtgt ttaagaacca gggcgaattg ttccgaatca ataatctgat caattctaat
     4321 gtttttgatt gttgccgtaa ggctggcaag gagaaaatca agggtgttat ctatgttggt
     4381 accgtatgct ccttccctct gaccagacag aatactttga atcctgagcc tctccgtgaa
     4441 gaggagttgt tccctgctct tcctgagtct gcttatggct ggagcaaact gatgggccag
     4501 ttggagatgg ggtatttgga aaaagaaacc ggaattccgt gctgtatcct gatgctccat
     4561 aatgtttatg gcacacctac tgattttggc gaacgtagtc aggttattcc tgctctgatt
     4621 cgtaaagcaa tcaataatcc tgaagagcct tttaatgtgt ggggtagcgg agagcaggga
     4681 cgtgctttca ttcatgtcaa tgatatcgta aatgcattgg tgctcgccct ggataagggt
     4741 tggggtcatg gtcatattca gattggccct tctcactgta cttccatcaa ggaaattgca
     4801 tataagatca ttgaaatttc tggcaaagac atcaagcctt tctttgatac ttctaagcct
     4861 gaaggtgata aggctcgttg cgcagattat tctaaggcga aagagatttt ggattgggag
     4921 cctactgttt ctttggaaga gggtcttcgt gaatcctaca attggattga aaagcagatt
     4981 aagggttaat aagtatataa gctgttcttc ctccgtgtaa ttagaggatg cggaggaaga
     5041 acatatgagt aaggatgtac tgagatggaa aagaatatgt ataaaagaaa acgtgatttc
     5101 actgtgtgtg gaatagtagg tgtttgtgct actacaaaga acgagtttgt aagggaagtt
     5161 ttttccatgc caacatctcc ggtaagtgcg actgttgatc tcgtgggagt gccggccatt
     5221 atttcggcaa aggaaaatcc caaaattgct gaaatgtata gccaggctac aatggctgca
     5281 atagatggta tgcctattgt taaaattgga cggcgcaaag gatttacctg tgaacgatgt
     5341 gctgcaccag atattatggg aatggttttt gaagaaggcg ttagacaggg aaaaacacat
     5401 tatttctatg gtggaaaaga taacgaagtg ttaaataagc ttcgtgcaaa cctagaaaga
     5461 gattacccgg gaatcaaaat tgttggaatg tattccccac catttcgtcc gttaaatgaa
     5521 gaagaggata gcaagatttg cgaggaaatc aacaacttaa atccagattt tctgtgggtt
     5581 ggtattggtg cgcctaagca agaaatgtgg atgtgggaac accagaagaa gatccataac
     5641 acagtaatgt tcggtgtagg cgccggcttt aacttttttg cgggcacttt ggaaaaagct
     5701 cctgaatgga tggaaaaagc tagtctagag tggttattta gactggtaaa ggaacctcgt
     5761 agactatgga ggcggtatat cttgggaggt ataaagtata tctactatac tattgaatct
     5821 aagtaggggg gcaataaaaa tagatgaaaa tacttatagt agttacaatg acgaataact
     5881 ttggtaagaa ggggtcctat aattctcagg aaataggatt agctcgaggg ttagctgaat
     5941 taggccacga agttattgta tataaaagtg taaaaagtga tgaggaagtt ggaacagagc
     6001 aattaagcaa tacggcgatg attcactata tcaagtgtcg ttatgtagga tcaaatggat
     6061 tcttatcaac aaagaatttt gataagaatg cggatgttct aatacaattt gcggaccttc
     6121 aactatcagt acctcatgta tactcatgga ctgtaaaaaa tggaataaaa tatatacctt
     6181 ataatgggat aacgcgaagt caaagtggca ataaatatat aaagacaatt attgaaatat
     6241 tggcgcatcg aaattataaa atttataaga aaaatgggtg tgttgccaaa aatgatcgag
     6301 tttctgaaaa attagtacaa ttaggagtaa ataaagtgaa acttgctcct gtttgtgtgg
     6361 attttgaaca gttacataag aattacgaag caatagattt tactactctc agagaaaaat
     6421 ggaatattcc tcgcaatgtt cgtgttattt tatatgtagg acggtttgaa aaggataaaa
     6481 gaccgttaga tatgattagt ttatttaata aacttgatga gcataattat ttgctgatgg
     6541 taggaactgg tgctttactc gagcaaacga agcagcagat aaatttactt ggactgcaga
     6601 atagagtaaa aataattgag cgtattccta acaaagatat ttgggagtta tattgcttat
     6661 cggatgtatt tgtaaatcta aactatactg aaatttgggg tatggttttg ctagaggcaa
     6721 tgtactatcg cctcgggatt attgctgtta atgcacctgg cccacagaat attattttgg
     6781 ataatagata tggaatgttg gctaaatctg acgatgaaat tttgacattc ttaaaagacg
     6841 gacgatttac caacgatatc atagatgcag catatcagcg tgtaactaca gaatttagat
     6901 ggtcaaagtc gggagaaatt atgcttagca tgttggaagg tgataaatga tatggaagta
     6961 acgaaattaa tggcattgag gaatcgatat gctttaaaca tagttgataa ttgcacgaga
     7021 aaaatagcca aaattcttgg ttgttgtatt ggtaaaggtg cacagatagg gaactctgtt
     7081 gaatttgttc ataattctgt aggcactgtg attcattctg acacaatcct tgaagatggt
     7141 gttaaagtct atcagaatgt gacgtgtggt tgagcagata gtaatgaacg tatcatcatt
     7201 cgagtaaaaa agaacgctgt tttatgtgtg ggtgctaaaa ttctttgtaa atctaacaca
     7261 gaattatgcg ttggggaagg tgctgtagtt gctgcaaata cagtggtatt gaggtctatt
     7321 ccaccctacg aagtgtgggg ggtacctgct aaaaagatgg ggagataaaa catgaatgca
     7381 tataaattat acaaagtaga acgatggttt tacttacaca aaatggagtt ttttgccaag
     7441 attgtaaagg cactaattta tgtacttcat aatagctcaa tttcatatca aacagaaatt
     7501 ggagataatt gtaagttctt atacggtggc ataggttgtg taattggaaa agatacaaaa
     7561 ataggtaatc acgttataat cggaacgaat gtactgactg gtggtagatc caataagcct
     7621 ggtatgccta caattggaaa caatgtatat atcgctactg gcgcaaaaat tttaggtaat
     7681 atcacaatag gggacaatgt aatagtaggg gctaatgctg tggtcattaa tgatgttgaa
     7741 cctaattgtt cggtaggagg cgttccggct agagtattga aaaaagatat tgatgtaaat
     7801 gattattgta gtttgaatcg ttactaaaag gagagattgt atgttgtatt ttgttattcc
     7861 tttaatgagt gcgaaggcag caaacaattg ggagatggtt agtaccttat ttaaccgaac
     7921 attatggtcg tgttataatc agactgatcc tgatttcaaa atcattgttg cttgccatga
     7981 aattcctaaa ctcacgcatg aatatgatga cagagttgaa tttattcaag ttagcgaaaa
     8041 ggatgcccct attcccacaa atcaagacga aaaaatgatt gataagggtt ataaaacaca
     8101 tgctctcgca atgcgtttgc gagagttggg cggcggtttc gctatgatgg ttgacgcaga
     8161 tgatcttgta agttctcatt tggcggaata tgtgaattcc catccccagg aaaatggatt
     8221 ttatgtcaaa acgggatacg tgtactttgt tggagacgat tatatgaagg ttctaccaaa
     8281 gttctcatca ggaagtgcgt gtatagtaaa atatgcagtg gaagacctgc ctgaggcata
     8341 tccggaagtt atgacagcaa attgtgatga taatccatgg atcattagaa aacgacatgg
     8401 gggcgttgtt ccagcatgtg aagagcaagg gcgtccatta aaacctcttc cattcaaagc
     8461 agcagtatat gtattaggaa caggggacaa tcactcgctt tatggtaaaa cgacaaaata
     8521 tcagacgaaa atgcgagaga tactggaaat gtttatagca aaacgtaaaa ttaaaggaaa
     8581 actgaaagca gaattttctg ttgattggtt ataaggtgag tattatgaag gtattgatgt
     8641 gtgaaagcca aatgccagag aattggtatt cgtttgatct ttctaaagaa cttaatcaat
     8701 atgttgattt aacattgctg tgtaagcgtg atgttcctcc tttagatcct aaaattaaga
     8761 gcaaacatat tttgtatcat aaaagtacaa ataaagtgtt ttcggcactt gtttttctga
     8821 aaagcttgtt cttaatttgg aaggaaataa gatttggtga ttatgatatt gttcatttgc
     8881 aattgatgaa aagtctcaaa tatgaaggcg gattgtacgt tttatgtaag agacactata
     8941 aaaaattaat tatgacagtt cataatgtgt taccacatga ggttcgtgaa aaggatcgcc
     9001 aagagcactt taatatatat tcaaattgtg atggtttcat tgttcacaat cgagtaacag
     9061 aacagcattt atatgctgaa ttcccagaat taaatgcaaa gtcatatgtt tgtccacatg
     9121 ctatctatgg agatgttaaa catatatcta gagcgtatga taaagataag tttgaattta
     9181 tcttgtttgg acaaattcgt ccatataagg gaattgatgt actgcttaat gcaatcacag
     9241 aacttccaat ggatgtaaga aagaaagttc attttaccat agcaggtcaa caacatccta
     9301 aacaggatag tactgactat aaaaaaatga ttgaagattt aaaggtttca gattgtgttc
     9361 tatataagcc agagagaatt tctgatgaag aaatggacag tatgttcaga aatgcagatg
     9421 ccgcaatatt tccatataaa gaaatctatg gaagtggagc gcttcttatg gcatacactt
     9481 attgcttacc aactattgtt agtaatgtac ctgcttttat ggaagaaacc gaggaaggaa
     9541 agatagggtt acttttcgaa aatttgaatt ctaagagcct agcagacaca attgtaaagt
     9601 atgtgaacct tagcccagct gagaaaagca aaatagagga tgatatatat gagcttgtaa
     9661 accgcaagta tacctgggcg gcatctgcaa aactcacata cgaggcatac aaacaaattt
     9721 tgaatgagta gtaaaacaat tagaaaggaa taataattaa catgcagatt agtaaatgga
     9781 aaatcataca gtttctaatg gtctttctaa tgattatctc atcaagcata ttgaagcctt
     9841 tgggcggctg gttgggagaa acgatgaacg ttagacttgt gacagtcatt ctagcaatag
     9901 tatgtttgtt aatagcctca ttaccagcat ttagaaaaaa tagatattta aatttctgca
     9961 ctttactgat ttgtgttgtt ataatagcag cttacatcta ctcagataag acaatatggg
    10021 ttaaatctag ggaaagtatg agtttatact atgtattatt ggcgtatcca ttgttctgta
    10081 ctttaattaa ccaagcgtgg aatttggatt caatgctaaa tacgatatgt ggtgtaacat
    10141 ttctttcata cattcttaga acatctattt cacttattca gaaattttca ggagtacttc
    10201 tctatgaaaa catatatcgt gagtgtgccc cggaaaattg gtatcgtgga ggctttttaa
    10261 gaattaatcc accatgtttt acaattataa taataccgat tgctttgtat atgattgagc
    10321 gacaagttgt agctagaaga aaagtaaaat attatttact gattgctagc gcactggcat
    10381 attctgctgt tattcatggt tctagatctg tccttgtcta tcaaattatt gtacttggtt
    10441 gctatatcct ttttaagaaa ggttcttcga aaagaaaaat tgcaatgtgg gttttagctg
    10501 ggttgcttgt agtcatattt attaattcga ccatgttctc aacatttgtt gaaactttca
    10561 caaacagtac aggtgaatat gcaggatctg ctgaatctcg atttgcttca gtttggtttt
    10621 ttattcctaa atttttgcaa tcgcctttgt tcggtactgg tattcttact ggtgaggaat
    10681 ttacgtttat attaccagga ggagttagag gacacctatc tgatattgga tttttctata
    10741 caattactca atatggtgta ggtatactta tatttgatat tctgtttatt ataaaagggt
    10801 tcaaaacagc attacttgca tcaaaagtgg gtatgactgg ctatcaatat ttagcatttg
    10861 gaattacatt aaatgtcttg ctaacaggga ttaatataga ctggttttat ccgatattta
    10921 ctccagctat tcctgtatgc ttagcggtta tagaatacat ctatcaagaa tgtagaagtg
    10981 tggctaacat agaataggaa atattaatag gagtgcatct catgaataag aaagagattt
    11041 tatataacat attgaagaag tacgaaaatt taccatatgt gtttaggaac atgtttggtc
    11101 ataatataag taaactcgta tcttggaaat tgactgctga ttgtgcaaca gtagaagaaa
    11161 attctgaagt ttatgcagcg tttcaattgc gctcaaagga catgtctgat gttccagtga
    11221 tgggtttagt taattgttgc aaagatgtag caattgtaat gcaggggcca ctatgtttaa
    11281 aggatgattt ctcttataat actctggcct actataagaa atgttatcca aatgctttaa
    11341 ttattctttc gacatggaag gacgaagata ttaaggcatt gaaaaggata gaggatcttg
    11401 gagttatagt tatttgtagt gagaaacctg aaaagcctgg acacttaaat attaattatc
    11461 aagttggaaa cactttgcct ggaatagtca gagcaaagca gcttggtgca aagtatgttt
    11521 gtaaaactag aacagatcaa agaatatacc atccaaatgc aatggcgttt ttctgcagtt
    11581 tacttgaaca gtatcctgtt aataacgaag atgattggaa attaatacaa aatcagcgat
    11641 tactgttact atcaatgccg tatggagaca tgtttttccc gtattgtttg tcagacttcc
    11701 tgtattttgg tgatgttgat gatatgataa acctcttctc gattcctagt gatgtgagag
    11761 aaaagggagc tgtgtctaga ggagtctcaa gaagggagat atctgaaaat aatttagctc
    11821 cagaagttca gcttcttcga agctatattt cacgaatggg gggcaatgag gagtgctcta
    11881 ttagggcata ttgggagttt gtaaaaaacc atgttattac tattaacaaa aatcaaattg
    11941 atttgtactg gcataaatat gtaggtcgtt attcaaataa tactatttat ggtacgtatt
    12001 atattgatga tagccaagat gcacttcact gctataattt tgattttata aattggttga
    12061 atttgtacac tggaaaatac gaatacaaag cagaatatga aaaatatatg gactttgttt
    12121 gggaagagta attaactttt atagtaaaaa gtactttagg gaagggcata ttatgaaaac
    12181 agtaattatg gcgggcggac gaggaagccg aatttcggaa ttgtttccgg atattcctaa
    12241 gccaatgatt cctatagatg gcattccagt tttagaacga gaattgtgtt cgcttagaga
    12301 tcaaggcttt aatgatatta ttttgactgt ttcctatttg catgaaaaaa tagaggagca
    12361 tttcggagat ggttcaaaat taggaattaa aatcaaatat tttattgaaa aaactccact
    12421 tggcaatgca ggtgcattgt attttttgtt ggatgaactg ggtgatgaac cgtttttact
    12481 tttgaatgct gatgcagtat ttgatgttga tttcaggcag atgattagat ttcatgttga
    12541 gaataacgca gatgttactt tgtttacgca tcctaactca catccgtatg atagtggatt
    12601 aattatatcc gatgacaata agaaagtgct tcaatggtta gcgaaggaag atcaaagacc
    12661 tgaatattat aaaaaccgag taaatgcagg tcttcatgtt ataaatccga aggtgttgag
    12721 agaaaatcca ttaatggaaa ttgtaaataa atcaatagtt gaaggtgggg ggctaccata
    12781 caaaattgat ttagatagaa tgattctgaa accattggct aacacagggc gtatgtattg
    12841 ctacgattct ccagagtatg ttaaagatat gggaacaccg gaccgatata gagctgtaat
    12901 taaggacttt caaaagggaa ttattgttgg taaaaatcta tccaatccac aaaaagcaat
    12961 ctttttagat agagatggaa cgattaataa atacgttggt tttttgagaa atgcagaaga
    13021 atttgagtta attgatggag tatcggaggc aattaaaatt attaattctc taggttttct
    13081 gtgtattgtt ataacaaatc agcctgtaat tgcaagaggt gaagttactg ttgatgagct
    13141 taatagtatt cacaataagc ttgaaacaat gctagggcat gctggtggat ttttaaacgg
    13201 tatttattac tgtccgcacc atccccataa aggatatgca ggagaggtta tagaattaaa
    13261 aattgattgc aattgtcgca agccaaaacc tggactgtta ttagaagcat caaaggattt
    13321 taacataaac ctaagtcaat catttatggt tggagatagt gaaagtgatg taattgctgg
    13381 aaaaaatgct ggttgtaaga cagtactgat tacagaagac atcaccttgc ctgctaatta
    13441 tggccaagac tatagtgtct gttcattgtt agaatttgtt aaaaatcatt tatgcactat
    13501 gcaataattg gtttagtgaa acttgtaaaa ggagtaatta gatgaaggta ttaattccag
    13561 cagcaaaagt tgttgaaaaa gaattgcaga gtataggaat gttaccagca attatctatc
    13621 caattaataa aaaaattgtc tttgattatt tgtataatca gtataatgca atctgcgatt
    13681 cattggatat tatctgttat gaaaaagcgg ataaggttca tagaagactg aaaaactatc
    13741 atgattccag aattcatata tgtgaccttc ctgaattagg ggatctaggg caaaccgtgt
    13801 attttgggtt atcagatgaa gatgagcctg ttctaattaa cttcgcagat acaattgtta
    13861 tggagagtat gtctgatata gaaatggata cattctatta ttctgaagat tttgtgtcga
    13921 gtacttggac atactttaaa attaatgaag gaataattac tgatatccac gataaagagg
    13981 aagcttacgt atccgataaa cgtgaaaaat tatttattgg cgtatttatg ttttcttcgt
    14041 caaaacttct gaagagttgc ttaagagagg cagttgagag tcggaaacag gggggaataa
    14101 actcatttta tcgggcttta cagctataca gcgaacgttg tccgctaaag gccgtaagaa
    14161 cagaaaagtg gtttgatatt ggacacatcg ataaatatta caatacaaag ttggaagtta
    14221 aagcacgaga gtttaatcat atctctatag ataaagatcg agggatattg aagaaaacta
    14281 gcgatgacaa ggataaattt attggagaaa taaagtggta tttaaaactt cctgctgata
    14341 ttgaatatgt aagacctaga atttttgatt attctacatc ttacgtagct ccctatgttg
    14401 atatggaata ttatgcatat catacggttc atgagttata cttatatggt gatttaaaat
    14461 ataaccagtg gcatgatctg tttagccgta taaagtttat ctgtagcgat tttaagcgat
    14521 acaccttaaa agatgaaaag attagagagt cattggaaga tatgtatttg cgaaaaacca
    14581 tgcagagatt tcaaaaattg tctgaagata aaagattttc agcttttttt gagaaacaaa
    14641 ttcaaattaa tggtcgtaag tttatttctt taaccggtgt aattgaactt ctaaagaatc
    14701 ttatcccaag tatgctctat gatgtaaatg aattttgtat tatacatgga gatttgtgtt
    14761 ttgctaatat gatggtagat tccaattgtt cctttgttaa ggttattgat cctaggggaa
    14821 aatttggaaa atatgatatt tatggggaca gcagatatga attagcaaaa ctatttcata
    14881 gtttagatgg taaatatgat tatatcatca aggatctatt tactgtagaa tatgataccg
    14941 agtgtgcagt gatagattat acaattaata cgcgtgtaag agattacgat ttatttgaat
    15001 tgtttaagtc ggtcttttcg gacgagatta aggacgattt tgataagatt gtattgatag
    15061 aagcgttgct atttcttagt atgattccat tacacggtga aagttttgat caccaaatag
    15121 tgatgcttgc tacaggtatg gaacttcttg caagagtaag taataaagtt atactctaat
    15181 ataaattgtg ccttaatgaa taacggttac aatactgttt tagcaatgta ggcattaagg
    15241 cacgattata ttaattaata caatagaagg gaagagaaaa atgtatagtg aatattcttt
    15301 tgtgtttgat atcgatggca ctttgtgtcc gataaagaag aaggatgagc gatatgagga
    15361 tttggtgccg tatgagaata tggttgaaaa actgagattc tataaggaga atggtgctaa
    15421 aattacattg ttcacctcac gcaatgttaa ttcctataaa ggaaatttgg gaatgataaa
    15481 tgctaatact gcaaaagtgc tcttggcgtg gttggataaa tgggacattc cgtatgatga
    15541 aatcctgtat ggtaagcctt ggccggggca taaaggcttc tatgtagatg atcgaacggt
    15601 tagacctgat gagtttttga gatgctctgt agatgaatta aatgaaatct gcaacagttc
    15661 aaaaaaaaga ttctaaataa ggaggttagt tctatggaaa aaaagatgac agttatcatt
    15721 acgatggcag gtttgggaag tcgttttcga aaaattggtt atgcggttcc taaatatatg
    15781 attaatgcca aaggaagaac tttatttgat tgggccatgg atagtttggt tggatacaat
    15841 aaaaatgttg ataagtatat ttttgttgtt cgtcaggaag acaacgcttc agcttttata
    15901 aaggagcatt gtgcttactt tggtattgaa aacgtagaag tgattgaaat agactatatg
    15961 acagatggtc aagcaactac atgtatgttg gctattcctt attgcaatca agacaatgag
    16021 attatggttt acaatattga tacatacgtg gaatcaaatg agatgaaata cgaagatatt
    16081 tgtggagatg gacatattcc atgctttcat gctgatggcg atcattggag ttttgcaaag
    16141 cttaacgatc gaaatgaagt aatagaagtc cgcgaaaaag ttcgcatttc tgataattgt
    16201 actcttggtg cgtattattt ctcatcggca aagctgtata aagctttata tgaagagtat
    16261 tatgcagact cctctaatat ggagaagaat gaaaaatata tagcaccatt atataacttt
    16321 atgataaaaa aagggttaaa ggtgactatt agcatagtag atgcgaaaaa ggttcatgtg
    16381 cttggtactc cagaagagct caatgtgttt ttgaatcaag aataaatagt gtttaggaga
    16441 aaatagcagt gaccagtaat aatctaattg taaaaacatt aagcagatat aagaatactc
    16501 cacttcctgt taaggctgca ttatggttta tggtatgtgg ttttttacag agaggggttt
    16561 caatgattac aaccccaatt tttactagag ttttgtctac agaacaatac ggtttataca
    16621 gcacttatct atcgtgggaa tccttattgc tcatgattac atcgcttagt ttgttcaaag
    16681 ccatgatgaa tctttatgta aaatatgata atcaagaaca tattctttcg acagtatccg
    16741 gattgacttt agtactgact attttttggt ttgttattgc tatttttatt aaggatatat
    16801 tggcagaaat tttaggattg acaccagttc tagttgtctg tatgttctca tattttatat
    16861 ttcaggcaga aatacaatgt tggtctttac acaaacgata tatatatgat tataagactt
    16921 tattagtagc tacccttgca gttactgttg gctcatctgt agttggctgt ttagcggttc
    16981 tgtttatatc tcctaccgct gaggcgagag ccttaatgaa tgtcctagtg actggtgttg
    17041 ttggcgtggc tgtgtatata tcggtattta gaagatgtaa ggattttaag gataatgaag
    17101 tgtggaattt cgcagtagta ttttgtgtat cgttgatgcc acactattta tctgaattta
    17161 ttctgaatgg ttctgataaa attatgataa attacttatg tggttcgtca gatgttgcta
    17221 tttacagcgt ggcatattct attggtgctc taattaacct tgttacaaat tctgtcaatt
    17281 ccacttttgc accttatcag tatcaaaaaa tcaagtcagg agaatatgat ttactatcaa
    17341 aaagagctaa tgaagttctt ggtttggtag cggctatgct ttttgcatta atgctattta
    17401 gtaaagaaat tgtgttgata tttggtgggc agaaatatat cgacagtgtt aatttaattg
    17461 tacctatatg tatcggtatt tatttcaact atatgtttca gctgtttgct agagtacagg
    17521 aatactttga aaagaaactc actgtcgtta ttccatcggt tttgtgtgca attatgaata
    17581 ttgtactaaa ttatgttttt ataaagttat atgggtatca ggcggtagca tacacaactg
    17641 tattctcata tatgtttttc tgcgtcatcc attatatttt ttatagaaaa gtttgcaaag
    17701 aactattgga tggaaaaaac atatatgatg tcagaggaat acttttgatt tctgcaatca
    17761 cgatagctgg tggcatccta atttcaataa ttaataaatt tgatttcata aaatatttaa
    17821 ttatagcaat tgcttgtgtc gctgcaatta tatttagaaa acgattgcta cttttagtaa
    17881 ggagaattat gagcaaataa acatttgctc atagagagat agagaatgat agatattatt
    17941 tctgctataa cggtaaatgt attaacagca ttatatcagc cgttcttatt tgccgtatta
    18001 acagcgtatc tgtttatgta ctggtatcta tttatagttg ataactctcg agatcctaaa
    18061 aacttaaaag attctgtatt aatctggttg agatatttta aagcatctag taaatttcgc
    18121 agactctttt ttcttgcgtt ttattttact ttgatattat ttaaaacctt gcttaatcga
    18181 aatatgtgga tgaacccgct ttcaaacgtt attggacagt ggtcattata tattatagat
    18241 aatgctacag gagagagcag attgacaaca gaatgcgtgg agaacacgat gctgtttatc
    18301 cctttttgca tgttattgtt atggtggcgt gacattaaat gtgatattat acgcaccatc
    18361 tatgttggga ttaagtatgt gtttttattc tcattaagta tagaatttac acaactgttt
    18421 tttaggcttg gtacatttca actatcggat ttgttttata acaccctagg gggcttaatt
    18481 ggtgctttgc tatattggct attctaccga ttaaataagt atatagactt aaaatagaac
    18541 tgctttgaat tttaatatgg ttaatatttt tctgcagaca ggattgtgta atctcatcaa
    18601 gaatacttta catgccatct atttttgcta aaacattgtt gttatatctt caagaggtag
    18661 ggaattttat tgctttaaat gaggtcgagc gaattaaaaa attggtaaaa tatataacat
    18721 ggtggtagtt atggtaaaag tgtttgatat aattaagttt tcggatttca gaggatatac
    18781 tgctgttgca ttggataatg agactctttt ctcgattggt attgagtttc acattaagca
    18841 aataaatcaa ggatttagtc ataataaata tactatgcga gggctacatt atcagagtgg
    18901 agagcatgct caaggaaaga tagtgatgtg cctacatggt gaaattatga atatcgcact
    18961 tgatattcga caaggatctt ccacttatgg atgtgtgtat gtcaacacat tgagtgaaag
    19021 caatggtaaa tgtgcgtata tcccacgtgg atatgctcat ggctatctta ctatggagga
    19081 caatacgcta gttcagtggt gcgtagataa tgatttcaat tctaatgctg ccaaatgtat
    19141 aagttatgaa agcgtagata ttgaatggcc ggtcagtcgg cagtgtttcg ttataagtga
    19201 gaaagacaaa aatgtggaaa gattaagctt ttgattaaaa tgagctgtgg agaaaagaag
    19261 gatactggaa aataagaaga acaataaccg agcaaatgct cggttatttc tatgaggaat
    19321 acataaaact aaatttagat atagatatac ccgtggtgct agttaatttt aatatcctaa
    19381 agaatatctc aaagttcctt caaaacgtcg ttgtgctcga cttaatagaa cactgtaagc
    19441 cagtaatatg ctttcaaatc tactctctag ccctttaaca gaacgtgagt tgaaattttg
    19501 acaacctaat ttttctaagg aagaaaaaac agtctcaact gttttt
//
LOCUS       DADVXM010000045        19486 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.048, whole genome shotgun sequence.
ACCESSION   DADVXM010000045 DADVXM010000000
VERSION     DADVXM010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.048"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            72..1244
                     /locus_tag="KB927_001709"
     CDS             72..1244
                     /locus_tag="KB927_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6840628.1"
                     /translation="MSLFDIFKQSIKNEDPSDWIPDFVFGDEESARAYLKIMAKSTVL
                     DFVARTMSTLEVKFKNKDGTSDWDYILNVRPNSDMSAATFWQKFFYRLLDDNEVLVIF
                     TDDNQLLIADDFSRTEYAVYDDVFTNVMVKNFVFERSWAMSDVIYMEYNNEELERFTR
                     GLFEDYAELFGRILEVAMRNNQIRGSVSIDSTGTANDEKGKDGKTRSQRLQEYIDKIW
                     NSFKTNSVAIVPKVKGFEYEEYTNKQGVSNQSLDELNKMKSSLIADVANAIGVPTALI
                     YGEKAELDSNIKAFRKLCIAPLVKKLQDELVAKIISRQEYKNGERIEVKKVLQKDLLE
                     YATQIDKITSGGAFYIDEVRDEVDYDELPNNEGKIRIRTKNYEETVKGGENDNAES"
     gene            1231..1935
                     /locus_tag="KB927_001710"
     CDS             1231..1935
                     /locus_tag="KB927_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBB6840629.1"
                     /translation="MPKAKKVPFQFTNEIQNGKHILTLSGNVQKKYWRDDDVINAKDI
                     RDSLDTVTDDIVIKLNSPGGDVFEGIEIYNYLKDHPSNITVEVTGLAASAATFIVAGA
                     NDVIMNVGTSLMIHEASTFAWGNKQDIQKTLNALETIDDSILAIYSDKTGQSVDKLRE
                     WMNEEKWFTADEAVKYGFANSVKREEPQNEPQNIAAMIQDAVAVAIANLKEPVTNKIE
                     QESKQKSLIARLRKGE"
     gene            1940..3100
                     /locus_tag="KB927_001711"
     CDS             1940..3100
                     /locus_tag="KB927_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6840630.1"
                     /translation="MLKITDKTADAKKAFNAISSKEDATPEQINAALEEYVTAIAEDA
                     GKQVRAEYEELKNVTDNRVLEARGIPTLTVEETKFYNEAVKSGGFDSDVVWPETILER
                     VFENLQNDHPILGLINFTPTVGRVKVIRARRKGVAVFGPLHKDLEGQLDAEFGATEFV
                     QLALTAFFLISNDTLDLGPRWIDRFINLSLSEAVRDVWAKKIITSSGKDEPIGLLKDL
                     DGAVTSGVYPDKASAGTLTFAKEKIVLELAGVMKKLSKYTYKVDGDDEGEVEYRSVAG
                     RVYLIVNPVDYWDIVARVTFANLNNVYGTTMPFIAVDHIIESVDVPESKCIAYVDKEY
                     EATQSRAEKVYVYKETFAMKRATLYAVDMLGNGYPTNNDAAQVYDLDFTAGE"
     gene            3176..3454
                     /locus_tag="KB927_001712"
     CDS             3176..3454
                     /locus_tag="KB927_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBB6840631.1"
                     /translation="MNTEEFIKEYKARFRIFHTSEDEDIGKQLESGFADIKSLIGSFD
                     PSTYEKGKELVYERTRYLRNESLEYFYDNFQTMIMDASIDLAGAGYAN"
     gene            3435..3806
                     /locus_tag="KB927_001713"
     CDS             3435..3806
                     /locus_tag="KB927_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBB6840632.1"
                     /translation="MLDMPIKSNYKKPKIVAGDLNTPVTFFEFQPNKGPEPGDEEKKE
                     LYFCTALVYNPSMKDRDILGTKEGVTIKIRDPHQSYIPTNKHKVRILDYRYGDKVWEI
                     IDVSPDLEENSIVKIVLELIT"
     gene            3822..4226
                     /locus_tag="KB927_001714"
     CDS             3822..4226
                     /locus_tag="KB927_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840633.1"
                     /translation="MSNVKFEGVQETIQALEKKFGEKKTKTLTKKAINVGAEKVEKQL
                     QTDMTVFKDKGYTIDEVVRKNATYRNYKAEAEIGWNGPHQRYRIIHLNEWGYTRKGKQ
                     IRPRGFGVITKSLKNSEPLYFDAVGEEVKKRL"
     gene            4223..4633
                     /locus_tag="KB927_001715"
     CDS             4223..4633
                     /locus_tag="KB927_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840634.1"
                     /translation="MKDMLNIIYEALCLNEYIRSMTYNENTEQYRIKFYEQPETADKT
                     GPMITLRPVDTPNEAYHGSNKELSVEHMVQIDVESKYRATCKQIQYEIKKEMKKLGFG
                     QISGQGLDEYFSETKRFVDARRYEGNTKIYDTEY"
     gene            4694..5281
                     /locus_tag="KB927_001716"
     CDS             4694..5281
                     /locus_tag="KB927_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6840635.1"
                     /translation="MTLVGFKKMTIGIFDSTGKIPAANLYVIEGEQDKGATVSAEISG
                     LSKEPSKVYGSNIAYYVSQKGTGDVSATFGLLDLPTEVNDKILGYKTDTNKISFLGED
                     TEPPYCAILMESEDLNGDTAMLAMFKGKFSRESINLNTTTNEAFEPEAEEYVFSAIAN
                     DVEGDAKGQTVAKYVGDEEASITALKEMVFPAAGE"
     gene            5354..5821
                     /locus_tag="KB927_001717"
     CDS             5354..5821
                     /locus_tag="KB927_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig domain-containing protein"
                     /protein_id="HBB6840636.1"
                     /translation="MPDTFKIYKKNGTEFTKVAEGESPLSITGIAANTQVAKGDYQAT
                     RVVGGQESVKVDIPAFTTLPISVTGVTLDKTTAEVEQGGTLKLTPTVTPANATDKTGS
                     WSSSNTAVATVTGGNVTVKTDAEVGGTTEVSFTTTDGGKVAKCTITVIEKAAG"
     gene            5867..6175
                     /locus_tag="KB927_001718"
     CDS             5867..6175
                     /locus_tag="KB927_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840637.1"
                     /translation="MAKVRIELKEESGKKVYENIDTTGKDYRKALETIKKLNEDGVMI
                     WNRLDIYLDFAVGIFRDSKLTAEQILDGLPSEKVMSTLDDILGEVMGIESNPDPDAKK
                     "
     gene            6370..13134
                     /locus_tag="KB927_001719"
     CDS             6370..13134
                     /locus_tag="KB927_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBB6840638.1"
                     /translation="MANGKPLGNMIIKLDLDSSAFSKGLAGAKNAVNHQMKAMKSQMQ
                     VMNSSGNSLGALQAKYNGLGGVLQANEKQVELLTKAYKDSFDSNGNATASTAKYANQL
                     NQATARSASYESQMKTTVGQIARMKVETEGITGKLKANSDVLINSGKKIEAFGKGVSG
                     IGSALTVGVTAPIVAGATAVTSAAISWESAFAGVKKTNDEVVDSNGNVVYSYSDLEKG
                     LRDLATKLPASHQEIANVAEAAGQLGIKTENVVSFTKTMIDMGESTNMSAETAATSLA
                     RFANITQMSQKDFDKLGSVIVDLGNNFATTESEITEMGLRLAGAGKQIGMSQGEILGF
                     ATALSSVGVEAEAGGSAFSKVMIQMQLAVEKGFGAFDQLKQMAEEQGVPWVNLVNAVR
                     DGGKSLKAVSEQMGFTSSDLKKMYKEADNSKSSLENFANVAGVTSEQFQKLFKSDPSE
                     AIIKFIQGLKDSEKHGTSAIKVLDDMDIKEVRLRDSLLRAANASDIFKGAIEKGNGAW
                     KQNTALTNEANKRYETTESKLKMLKNEVIDTAIDLGGPFVDALRDGLNVSKPLIKNLG
                     NMAKAFSAMSDDQQRNIIKWVGLAAAAGPALKLLGTGTSVIGKVTSTTGRLTKSLVDL
                     AAKAAEKKALDAFASSVTTAGAAAAKTAGAGGIGGLVPMMGKTASAASTAAGASGIGA
                     MTTSLGLLGPALLGIVGVGGALAVGYGAWKLFGEEAWNSSQRVKQWGTDVGEEIDNTL
                     DGVQKNIEGANGQFGLLKEGFTVDDANNMAANFATAGTSLETSLTGRIKALDDALKGL
                     PQSVQDAMKEVAESEEETLGQSLSKIKDNNEEIKKIRERAANQNRDLTVSELQQIQDL
                     MKGTSQAYVDTLDVSAKDRKKILSAMNGDVAQATEEEAKTWLQSLAKQKAATTENYRQ
                     MLEEKKAALKEKGVSKEFIDALEDEMNDYIKTTNQGFDSQIAAITNKYPQLINEVSLS
                     NGQLFSKTAAAMDNTGQYTKVFLESNEKILAQAKKTSDEIADNAEKNAEQLGMVADEA
                     THAGSTWNGLVLDEKTGKVKTNVQEVVNEATKDFTKWNELKPVVHDAKLTTNAKDVIS
                     IAAVQNGYWDDMEWKEKEALLEDECSKNVYKALENAGKWNELDIPSKEAILTSNTPEV
                     MGETLMNLGLWDTYKLQVKDLDLNAYKVYDAIDGSEEKLNSWAQLDNPTKELLLDNSD
                     FSTKLFNSEEMFKRWNQLSSNAKFLSANNTKFTEVLLSSDRMWNQWVNLPDNEKRLLA
                     DNEDLATTVLSSEEIYGRWTQLPDNQKYMLADNTDLANKIFASEESWNAWKAIPDIVK
                     NLLGNNIDLLAKVKDGTVSVEEYNKVMPLLKTLYGDNVNLKEAISGAKSSIENYNKNI
                     FPNDKTAVGHDEASQAAKDAFEAFNIFQTKIPDKITKTVSADFIGPMPNAKGTNFHPG
                     GAAMVNDQKGPTYEELITLPSGEAFIPKGRNVVLDLPRGSKVLNATKTKRLVPKYADG
                     IGNITTVSSTLNLDALILAINELTTVLRTQLMAETTNAKDTKLSDETKVADPIIPGSL
                     SEKSDQYLGIGAQWLTNLMNGWNSAVPQYMNSEMVFITNYLNALKLQNNPNYTQGVAW
                     NKNLLNGWNSLTGTFISTINSFCNQAMVTLRNYNTPMYNNGRTWQQNNLNGWNSLYGS
                     FIARVNQLGNDSINNLRSKSGGFYNAGTFLLQSLINGMNSLGNSLSTTMNNVANTMVG
                     GMGKGVNGVISGVNYVLKEVESSKNIGNWPIPQYAKGTDGHPGGLAMINDQKGLVHEE
                     YVQMPDGRGFIAKGRDLLVNLPKGAQVLNASLTKKLKERLNIPHYEKGIGNLDIVDLL
                     DDEKRMLEFLTSKVDFSGINEPWLDMTKSGTSLMSKAANTMLQSKLSEFFTHGNFDGA
                     VNANGVYQYLVDVAQKVMGKFPGLTVTSGYRAGDAYYHGKRQAIDLAYPGISGDPRYT
                     AAANYAFEKFPSKIAYVITNGRVRDRMGLSGTGSSGQWTNWPDGDHFDHIHLNGSMGS
                     GDIFNGGVGGSGVARWRSYVSKALKMNGLPATAAYINAWMSQIQTESGGNEKAIGGND
                     GLAEGNATGLLQTKPGTFAANAFPGHGNIMNGFDNMLAAINYAKKRYGVAGMLQVIGK
                     GHGYANGGLITKDGLYRAGEGNKPEMVIPLTRKTRAIELMGQALAFLSGDDKKRSNTT
                     NTADNSAELVTLIKQQQKQHNELMMILRAILGKDLSLKSSDIGQAANHYMGSDLNKLR
                     YTNGGV"
     gene            13138..13959
                     /locus_tag="KB927_001720"
     CDS             13138..13959
                     /locus_tag="KB927_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HBB6840639.1"
                     /translation="MFYKLQFNQNGKLFDPQRKEKIVCKEIKRQAPVYEVNYEDFEGT
                     NGSREANASFRPFELVLTFDIFYKNKHDKELLLTEFYELIFVGYQYYISYDLSPGKRF
                     KVNPTNFEITEEENDYSTIEITFSIPSGSAESSATTLTDFNLEEEWQFSQGLVAEDYK
                     YTHQTSHFIIYNAGSFEIDPREHYLRIALEGESEGNVTIFNKTTGDRFIYYPSLSTNL
                     GQTLVLDGVIPKLNGVSCGINTNHGLINLVEGVNEIEIQNITRVKSSWDFRFLYK"
     gene            13968..15011
                     /locus_tag="KB927_001721"
     CDS             13968..15011
                     /locus_tag="KB927_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6840640.1"
                     /translation="MTELIIRNYEQTKEEILVGYDKGSFYENWQQNETWEIGFTVTSN
                     SLNQEVFDLVEYESSVFYNGQEFVIKEMTRKALGQLLTKQVVATHIYYTVQDGYQYNT
                     VTGAKSISQLLTHVFSAGSRGFTWEVIDPNKKFLTVEQENFGNANYLKLINEILSDYN
                     AVVIPNNKHLTFYPASEYGQQTEEQIRYKYNTDEVSFDIDTYSLKTQIKGYGKLKDGA
                     NTENPKDSDYIFTPITYTSPESQKWGIRIQDPVKDERYTVSGNMLERLKTDLQDYPNI
                     SGSVTLKWKISPNKGDHVPFIYEPLNINTYIQVVGIKTYPAIPNKPPEITLSNTKKTM
                     TSILAEMAKKGVI"
     gene            15011..16063
                     /locus_tag="KB927_001722"
     CDS             15011..16063
                     /locus_tag="KB927_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840641.1"
                     /translation="MGLLKLISNRISTEWKEKFNKNIDYLNDLEKKLSDQDKSTNSRI
                     DNLVLHSGGDSPNEVVDARVNHKGETFATLQGRLTDTEKKVSESVSTLEKNQADIKAQ
                     VAQLNNSVETIIGGSADWINLYVSADLGSDQIGDGSEEKPFATIQMAVNQIPLVSIPG
                     IRIWVDDGVYLEDVFIRNVSATTIHIGPKNDTSVIDPSKSDMPVKLRSLAFYQCKGFF
                     KVTGLQFVDTINAPKNSGLIYSLMLLQGGYLSVDKCKFAEDNRNLTSAAIYTEGLSAS
                     NVYNTCYFYRQNIVVYANLMSQVLISQQTSGKENTTGARSKDAIIRGKFSVGFADKNE
                     DVKDLGLIITKGTVLS"
     gene            16063..18246
                     /locus_tag="KB927_001723"
     CDS             16063..18246
                     /locus_tag="KB927_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HBB6840642.1"
                     /translation="MAFKINESIIVIQAEATSPNRTNVVFWSHDRGTAKLRMKLVRKN
                     GIPQSLPEGTTVPIRLMFRSATAEGGYGKHDYLATIEDRVNGIVSIVLEDNILGYVGI
                     VEGSVYIDFPNDRSLDTAGRFTFDIKRSPIDDSTPELEDYYFNGFSQTIDKIEKILAD
                     GKQEIEQKITESETQIDAKLKNTNDKITKANQDVTTLNTNIDKANDRIDQTNQQISDL
                     GKLKKMYSNSIDFGNYDYSGNPNLLSKLSYDLIENQNTSAGTLSKGENSFKYNKISAE
                     VEGGVELYYKRRGIANWLPSNKTLVMTVKLRAGADYSPVDGKLILIRYRYVDSGTGKI
                     VLDLPINSNSITQEWKEFSITGTTPTFSPQAYHPWIQFRAQDGILGEIEMSYDIKIEE
                     GSTATPFQPNLLAEPYNMCREYPNENIADHTVKFPIESGDHQIYQGYTEEELMIGQTY
                     TITLKGTKPASQTFVAYNHWTARLGELKPVDGLTDVWSLTFTPTNVVAMPKLFRVYQY
                     PRSTVGACQIDWLKIEKGNTRTPNISQFKYFGEGLKDSNNPNDYSWDITPEYAEKGLN
                     NTVSLTEPETVLGLKNFKDGVQIDGVDVATVKNLGSVLQSGSGLTTIQSDKQSAFDEF
                     SYEFERIGDRVFFHARVKTNSTTAVASHVNLLEIPLGFQFPIGWTIVGVPLSVVQWTT
                     PQGEISALVITDSTGKQVVKFATNRVGNHYISGEWRTADSYPETK"
     gene            18258..18704
                     /locus_tag="KB927_001724"
     CDS             18258..18704
                     /locus_tag="KB927_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840643.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGLRADGEPL
                     TIADQMFDPKLNQWIVLANTLDHNDLNNLKAMYEALEHENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPTLKGGE"
     gene            18706..18843
                     /locus_tag="KB927_001725"
     CDS             18706..18843
                     /locus_tag="KB927_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBB6840644.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIISKEESA
                     S"
     gene            18878..19120
                     /locus_tag="KB927_001726"
     CDS             18878..19120
                     /locus_tag="KB927_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HBB6840645.1"
                     /translation="MKEEALQDVVERLVRIETKLDNYESLREKADSAKDLADKAYSVA
                     LNNAEDIKEMKNNNKWAWGYMIGLGITIIGYFLTKL"
     gene            19136..19333
                     /locus_tag="KB927_001727"
     CDS             19136..19333
                     /locus_tag="KB927_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBB6840646.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASALVAMLGKAYGWNGTDMIVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            19344..>19486
                     /locus_tag="KB927_001728"
     CDS             19344..>19486
                     /locus_tag="KB927_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6840647.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQIA
                     NNQ"
BASE COUNT         6881 a         3129 c         4205 g         5271 t
ORIGIN      
        1 ttattataag taatggagta tagtcctaga aatagggctt tttattttac cttgaaaggt
       61 ggtgaaaata tgtgagttta tttgatatct ttaagcaatc aataaagaac gaagatccat
      121 cggattggat tcctgacttt gtgtttggtg atgaagaatc tgctagagca tatttgaaaa
      181 tcatggctaa aagtacagtt cttgattttg ttgcaagaac tatgtcaacg ttagaagtta
      241 agtttaaaaa taaagatggg acatcagatt gggattacat tctaaatgtc cgacctaatt
      301 ctgatatgtc agcagctaca ttttggcaaa aattttttta tcggctctta gatgacaacg
      361 aagtgttagt gatatttaca gatgataatc aattgctgat tgctgatgat tttagtcgaa
      421 cagagtatgc cgtgtatgat gatgttttta caaatgtgat ggtgaaaaat tttgtctttg
      481 aacgttcatg ggccatgtct gacgtcattt atatggaata taataacgaa gaattagaaa
      541 ggtttacacg aggtttattt gaagattacg ccgagttgtt cggacggatt ctagaagttg
      601 caatgcgcaa taaccaaatt cgtgggtctg tctccattga ttcaacagga acggcaaatg
      661 atgaaaaagg aaaagatggt aagactagat ctcaaagatt acaagaatat attgataaga
      721 tttggaactc ttttaaaact aactcagttg caattgttcc caaagtgaaa ggctttgagt
      781 atgaggaata caccaataaa caaggcgtat cgaatcaatc actagatgaa ctgaataaga
      841 tgaagtcgtc tttaattgcc gatgttgcca acgccatagg agtacctacg gcgcttattt
      901 atggcgaaaa agctgaacta gattcaaata ttaaagcttt tcgtaaattg tgtattgctc
      961 cactagttaa aaaacttcag gacgaattgg tggcaaaaat aattagtcga caagagtaca
     1021 aaaacgggga acgtatagaa gttaaaaaag ttctccaaaa agatctatta gagtatgcta
     1081 ctcaaattga caaaataaca tctggtggtg cgttttatat tgacgaagtt cgtgatgaag
     1141 ttgattatga tgagttgcca aataatgaag gaaaaattcg tattcgtacg aaaaactatg
     1201 aagaaactgt gaagggaggt gagaacgaca atgccgaaag ctaaaaaagt accatttcag
     1261 tttactaacg aaattcagaa tggtaagcac attctcacct tgagtggaaa tgtacagaaa
     1321 aaatattggc gtgatgatga tgtcataaac gctaaagata ttcgtgactc tctagatact
     1381 gtaaccgatg atattgtaat caagttgaac agcccaggcg gtgatgtgtt tgaagggatt
     1441 gagatttaca attatttaaa agatcaccca tcaaatatta ctgtagaagt tacagggctt
     1501 gccgcaagcg cagcaacgtt tattgtcgct ggtgccaatg atgtgattat gaatgttggg
     1561 acttctttga tgattcatga agcttctaca tttgcttggg ggaataaaca ggacatccaa
     1621 aaaacgttaa acgcattgga aacgatcgat gattctatct tagctattta ttcagataag
     1681 actggccaat ctgttgataa gttgcgtgaa tggatgaatg aagaaaaatg gtttacagca
     1741 gatgaagctg tcaaatatgg atttgccaat tctgtgaagc gtgaagaacc acaaaacgaa
     1801 cctcaaaata ttgcagcgat gattcaagat gctgttgccg ttgcaatagc gaatttaaag
     1861 gaacctgtta ctaataaaat cgaacaagaa tcaaaacaaa aatcattaat cgcacgattg
     1921 cgaaaaggag aataaagata tgttaaaaat tacagataaa actgcagatg caaaaaaggc
     1981 atttaatgct atttcttcga aagaagatgc aacacccgaa caaattaatg ctgctctaga
     2041 agaatatgta actgccattg cagaagatgc cggcaaacag gtgcgtgctg aatatgaaga
     2101 attgaaaaat gtgacggaca accgtgtatt agaggctcgt ggaattccta cactaacagt
     2161 agaagaaaca aagttttata atgaagccgt aaaatctgga ggtttcgatt ctgacgtagt
     2221 ttggccagaa acgattttgg aacgtgtttt tgaaaatctt caaaacgatc atcctatttt
     2281 aggcctcatt aactttacac caactgtagg tcgtgtcaaa gtaattagag cacgtcgtaa
     2341 aggtgttgct gtttttggac cattgcataa agaccttgaa ggccaactag atgctgaatt
     2401 tggtgcaact gaatttgttc aacttgcgtt gaccgcattt ttcttaattt ctaatgatac
     2461 cttagattta ggaccacgat ggattgaccg ttttatcaat ctttctttaa gtgaagcagt
     2521 acgtgatgtt tgggctaaaa aaattattac aagttctggt aaagatgagc caattggatt
     2581 gcttaaagat ctagatggtg cggtcacaag tggtgtatat ccagataaag ctagcgcagg
     2641 gacattaact tttgcgaaag agaagattgt tcttgaactt gcaggggtga tgaaaaaatt
     2701 atctaaatac acatacaaag tagatggtga cgatgaaggt gaagtggaat accgttctgt
     2761 tgctggacga gtgtatctaa ttgttaatcc tgttgattac tgggatatcg tagctagagt
     2821 tacatttgca aatttaaaca atgtgtatgg gactacgatg ccatttatcg ctgttgatca
     2881 tatcatcgaa tctgtagacg taccagaaag taaatgcatt gcatacgttg ataaagagta
     2941 tgaagctact caatcaagag ctgaaaaagt ctatgtatat aaagaaactt ttgcaatgaa
     3001 acgcgcaact ttgtatgctg tcgacatgct tggtaatggc tatccaacaa ataatgatgc
     3061 agcacaagta tatgacttgg actttacagc gggggagtaa cgtcccctgc aattggtgag
     3121 ataacaccga cgactgatgg ggcagtcatt aatctttcgt aaatggggtt agagtatgaa
     3181 cactgaagaa tttataaaag aatataaggc ccgatttcgt attttccata cttccgaaga
     3241 tgaggatatc gggaaacagt tagagagcgg gtttgccgat ataaaatctc taatcggcag
     3301 ttttgatcct tccacttatg agaaaggaaa agaattagtt tatgaacgta ctcggtatct
     3361 acggaacgaa tcactagagt acttttacga caattttcaa acaatgatta tggatgcatc
     3421 aattgatctg gcaggtgctg gatatgccaa ttaaatcaaa ttataagaag cctaaaattg
     3481 tagctggtga tctaaatacg ccagttactt tttttgagtt tcaacctaat aagggtccag
     3541 aacctggtga tgaagaaaaa aaggaactgt atttttgtac agcactagtt tacaacccat
     3601 caatgaaaga tcgtgacatt cttggcacaa aagaaggcgt tacgataaaa atacgggatc
     3661 cccatcaatc ttatattcct actaacaaac ataaagtaag gatattagat tatcgatatg
     3721 gagataaagt ttgggaaata atcgatgtct caccggattt ggaagaaaat tcaattgtaa
     3781 agatagtatt agaattaatt acttaaattt ggtgataaac gatgagtaac gtaaagtttg
     3841 aaggcgttca agaaacaatc caagctttag aaaaaaagtt tggagaaaag aaaactaaga
     3901 cattaacaaa aaaagcaatc aatgttggcg ctgaaaaagt agaaaaacag ttgcaaacgg
     3961 acatgaccgt ttttaaagac aaaggttata cgattgatga ggttgtacgt aagaacgcta
     4021 cgtatagaaa ttacaaggca gaagctgaaa tcggttggaa tggtcctcat cagcgttata
     4081 gaatcattca cttaaatgaa tggggatata cacgaaaagg taagcaaatt aggccaagag
     4141 gttttggcgt aatcactaaa tcgcttaaaa attccgagcc actatatttt gatgctgttg
     4201 gggaggaggt taaaaagaga ttatgaaaga tatgctcaat atcatttatg aggctctttg
     4261 tttgaatgag tatattcgtt caatgacata taacgagaat accgagcaat atcgtattaa
     4321 attttatgag caacctgaaa ccgccgataa aacagggcca atgatcacac ttcgtcctgt
     4381 agatacacct aacgaagcat atcacggaag taacaaagag ctttctgtag agcatatggt
     4441 acagattgat gttgaatcga aatatagagc aacatgcaag cagattcaat atgagataaa
     4501 aaaagagatg aaaaaactag gctttggcca aatttctggt caagggttag atgaatactt
     4561 ttctgaaaca aaacgctttg tagacgcgcg tcgttacgaa ggaaatacaa aaatttacga
     4621 taccgaatat tagaaattaa gacacgaaaa taacgtgtct ttttttatta cccaaaatta
     4681 ggaggaaaat tttatgactt tagtaggatt caaaaaaatg acaatcggga tctttgacag
     4741 cacagggaag attccagcag caaatttata tgtaattgaa ggtgaacaag acaaaggggc
     4801 gactgtatct gctgaaatca gtgggctatc aaaagaacca tcaaaagttt acggatcgaa
     4861 catcgcttac tatgtctctc aaaaaggaac aggcgatgtt tcagctactt ttggattgtt
     4921 agatttacca acagaagtaa atgacaaaat tcttggttac aaaaccgata caaacaaaat
     4981 cagcttcttg ggagaagata ctgagccacc atattgtgca attttgatgg aatcggagga
     5041 tttgaacggc gatacagcaa tgcttgcgat gttcaaagga aaattcagtc gtgaatctat
     5101 taatcttaac actacgacaa atgaagcttt cgaaccagaa gcagaagaat atgtattttc
     5161 agcgattgcc aatgatgttg aaggtgatgc taaaggccaa acagtcgcaa aatatgttgg
     5221 agacgaagaa gcttctatta ctgctttgaa agagatggta tttcctgcag cgggggagta
     5281 actagctccg ttgttggagc aatcactccc actattaatg gggtaacagt tgaattaagt
     5341 taggaggata actatgccag atacatttaa aatctataaa aaaaatggta ctgaatttac
     5401 aaaagtcgca gagggtgaaa gtccactttc tattactgga attgcagcaa atactcaagt
     5461 tgctaaagga gactaccaag ctacgcgtgt ggttggaggt caagaatcag taaaagtaga
     5521 tattcctgca tttaccactc ttccaatttc agttactggt gtgacgttgg ataaaacgac
     5581 agctgaagtc gaacaaggcg gaaccttaaa attaactcct actgtaacac cagcaaatgc
     5641 aacagacaaa acaggaagct ggagcagttc gaatacagct gtagctactg ttactggagg
     5701 caacgttaca gtaaaaacag acgctgaagt tggcggaact acagaagttt catttactac
     5761 tacggatggc ggtaaagtag caaaatgtac tattacagtt attgaaaaag cagcgggcta
     5821 gtcttcggac tagctttttt atttggaaaa taatggagga atctaaatgg caaaagtaag
     5881 aattgaattg aaagaagaat caggaaagaa agtctatgaa aacatagaca caacaggtaa
     5941 agattatcga aaagctttag aaacaatcaa aaagctaaat gaagatggag taatgatttg
     6001 gaatcgttta gacatttatt tggattttgc tgtaggtatc ttcagggata gcaaattgac
     6061 agctgaacaa attcttgatg gcttaccatc tgagaaggta atgagcacat tggacgacat
     6121 cctaggagaa gtaatgggga ttgaaagtaa tccagaccca gacgcaaaaa agtaacaccc
     6181 gaagaagcag aagaaatgta cttaaaccta tgcagagagt tagtgaaagc gggatggtca
     6241 ctatctgaca tagaagataa ttcctttgaa atgatgatga aaattgcgtg cacttcgcct
     6301 aagaaagaga aacaaaaaga agttgatctt aaagacttct tgaaatccat gtagagagga
     6361 ggtaaacata tggcaaatgg aaaaccttta ggcaatatga ttataaaact agacttagac
     6421 agttcagctt tttcaaaagg tctagccgga gctaaaaacg ctgttaacca tcaaatgaaa
     6481 gcaatgaaat cacagatgca agtaatgaac tcttcaggga attctctcgg tgctttacaa
     6541 gcaaaatata atggtttagg cggagttcta caagcaaatg aaaagcaagt agaattgctc
     6601 actaaggctt ataaggatag ttttgactct aatggaaacg ctactgcttc gactgctaaa
     6661 tacgctaatc aattgaatca agcaacagct agatcagcaa gttacgaatc tcagatgaaa
     6721 acaaccgttg gacagattgc tcggatgaaa gtggaaacgg aagggattac ggggaaacta
     6781 aaagctaatt ctgatgtatt gattaattct gggaaaaaaa ttgaagcctt tggtaaagga
     6841 gtttctggga taggatctgc cctaactgtt ggagtaacag ctccaatagt ggcaggtgca
     6901 actgctgtta ctagtgcagc tatttcttgg gaaagtgctt ttgcaggagt aaaaaagaca
     6961 aatgatgaag ttgtagattc gaatgggaac gtagtttact cctacagtga tttagaaaaa
     7021 ggccttcgtg atttagcgac taaattgcca gcaagccacc aagaaatagc gaacgttgct
     7081 gaagcagcag gtcaattagg gattaagaca gaaaatgtag ttagtttcac caagacaatg
     7141 attgatatgg gcgaatctac taatatgtca gcagaaacag ctgcaacttc tttagcacga
     7201 tttgctaata taacccaaat gtctcaaaaa gactttgata aattaggatc agtcattgtt
     7261 gatctaggta acaattttgc tacaaccgaa tcggaaatca ctgaaatggg actgcggtta
     7321 gcgggtgctg gtaaacagat tggaatgagc caaggcgaaa ttctaggatt tgctactgct
     7381 ctatcctctg ttggtgtcga agctgaagca ggtgggtctg ccttttcgaa ggtcatgatc
     7441 cagatgcaac tagctgtaga aaaaggattt ggcgcttttg atcagctgaa acagatggca
     7501 gaagaacaag gtgttccgtg ggttaattta gtaaatgctg tgagagacgg tggaaaatcg
     7561 ttaaaagcag tatcagagca aatgggattc acttcatctg atttaaagaa aatgtataaa
     7621 gaagcggaca attcgaaaag ttcgcttgaa aattttgcga atgtggcagg tgttacaagt
     7681 gaacaattcc agaagttgtt caagagtgat ccttcagaag caatcatcaa gttcattcaa
     7741 ggactgaaag attcagaaaa acatgggact tcagcaatca aagttctgga tgacatggat
     7801 ataaaagaag ttcgactacg cgacagttta ttgagagctg caaatgctag tgacatattc
     7861 aaaggagcaa ttgaaaaagg aaacggcgcg tggaaacaaa atacagcttt aacaaatgaa
     7921 gctaataaaa gatacgaaac aactgaatca aagctaaaga tgttgaaaaa cgaagtgatt
     7981 gatacagcaa tcgatcttgg aggtccattt gtagacgcgt tgcgtgatgg tctaaatgta
     8041 tcaaaaccgt tgataaaaaa cttagggaat atggcgaaag ctttctcagc catgagtgat
     8101 gatcaacaaa gaaacattat caaatgggtt ggattagcag cagcagctgg tccagcgctg
     8161 aagcttttag gaactggtac ttcagtaata ggtaaagtta cttcaactac tggaagattg
     8221 acgaaaagcc ttgttgattt agcagcgaaa gcagcagaaa agaaggctct ggatgccttt
     8281 gcatcgtcgg taacaacagc tggtgctgca gctgcaaaga cagcaggagc tggaggtatt
     8341 ggcgggttag tccctatgat gggaaaaaca gctagtgctg caagtactgc tgcgggcgct
     8401 agcggaatag gcgcaatgac aacatcacta ggtttgttag gtcctgctct acttggtatt
     8461 gttggcgttg gtggcgcact agcagttggc tatggagcat ggaaattatt tggtgaagaa
     8521 gcttggaatt cctcgcaaag agtaaagcaa tggggaacag atgtcggtga ggaaatagat
     8581 aatactcttg acggagtaca gaagaatatt gaaggtgcaa atggtcaatt cggtcttctc
     8641 aaagagggtt ttactgttga tgatgcgaat aatatggcgg ctaatttcgc aaccgctgga
     8701 acatctttgg aaacatcttt aacaggtaga ataaaggcat tagacgatgc actaaaaggg
     8761 ctacctcaat cagttcagga tgccatgaaa gaagtagctg aatcagaaga agaaacctta
     8821 gggcaatctc tttctaaaat aaaagacaac aatgaagaaa taaaaaaaat cagagaaaga
     8881 gccgcaaatc agaacagaga cttgactgtt tcagaactac aacagataca ggatctgatg
     8941 aaaggaactt ctcaagcgta tgtggatacg ctcgatgttt ctgctaaaga cagaaaaaag
     9001 atactatcag ccatgaatgg tgatgttgca caggctacag aagaagaagc gaagacgtgg
     9061 ttacaatctt tagcgaaaca aaaagctgca actaccgaaa attatagaca aatgcttgaa
     9121 gaaaaaaagg cggctttaaa ggaaaaggga gtaagcaaag aattcattga tgcattagaa
     9181 gatgaaatga atgattacat caaaactaca aatcaaggat tcgatagcca aatagctgct
     9241 ataacaaata aatatccaca attgattaac gaagtgagtt tatcaaatgg tcaattattt
     9301 agcaaaacgg cagctgctat ggacaatact ggtcagtata caaaagtttt tctcgaaagt
     9361 aatgaaaaga ttttagccca agcgaagaaa acatcggatg aaatagcaga taatgccgaa
     9421 aaaaatgcag aacaacttgg tatggtagct gatgaggcta cgcatgctgg atcaacttgg
     9481 aatggattag ttttagacga aaaaacagga aaagtaaaaa ctaacgtaca agaagtagtg
     9541 aatgaagcaa cgaaggattt cactaaatgg aatgaactta aacctgttgt tcatgatgcg
     9601 aaactaacaa cgaacgcaaa agatgtcatt tccatagcgg cagtacaaaa tggttattgg
     9661 gatgatatgg aatggaaaga aaaagaagca ttattagaag atgagtgttc taaaaatgta
     9721 tacaaggctt tagaaaatgc tggtaaatgg aatgagttag atattccttc taaagaagca
     9781 atcctaactt caaatactcc tgaagttatg ggtgaaactc tcatgaattt gggactatgg
     9841 gatacttaca aacttcaagt gaaagattta gatttgaatg cgtataaagt atacgatgct
     9901 atcgatggat cagaagaaaa attaaatagt tgggctcaat tagataaccc cacaaaagaa
     9961 ttgttattag ataactcaga tttttctaca aaacttttta attccgaaga aatgtttaaa
    10021 cgttggaatc agttatcatc taatgcaaag tttctttcag ctaataatac taaatttaca
    10081 gaggttcttt tatcatctga cagaatgtgg aatcaatggg taaaccttcc tgataatgag
    10141 aaaagattac ttgcagataa cgaagattta gctaccactg ttttatcttc agaagaaata
    10201 tacggaagat ggactcaatt accagataat caaaaatata tgttagctga caatactgac
    10261 ttagcaaaca aaatatttgc ttcagaagaa tcatggaatg catggaaagc aattccagac
    10321 atagttaaaa acttgcttgg taataatatt gatttactgg ctaaagtgaa agatgggact
    10381 gtaagtgtag aagaatataa caaagttatg ccacttctta aaactctata tggagataac
    10441 gttaatttaa aagaggcaat cagtggggct aaaagctcta tagagaatta caacaaaaat
    10501 atttttccta atgataaaac tgcagtagga cacgatgagg cttcacaagc tgctaaagat
    10561 gcatttgaag cgttcaacat cttccaaaca aaaataccag ataaaattac taaaactgta
    10621 tcagctgact ttataggtcc tatgcctaat gctaaaggaa cgaacttcca tcctggcgga
    10681 gcagctatgg taaacgatca aaaaggacct acttatgaag agcttataac cttgccaagc
    10741 ggagaagctt ttatacctaa aggacgtaat gtcgttttag acttaccaag aggttcgaaa
    10801 gtactgaacg ccactaaaac taaacgtcta gtacctaaat atgctgatgg tataggaaac
    10861 ataacgacgg tttcatctac gctaaactta gatgctttaa ttttagctat taacgagcta
    10921 acgacggtat tgagaactca actgatggca gaaacgacta atgctaaaga tactaaacta
    10981 tcagatgaaa caaaagttgc cgatccgatt attccgggca gtctttcaga aaaatcagat
    11041 cagtatctag gaattggagc tcaatggtta accaatctaa tgaatggttg gaactcagcg
    11101 gttcctcaat atatgaatag tgaaatggtt tttattacaa actatctcaa tgcgctaaaa
    11161 cttcaaaaca atcctaatta tacgcaagga gtagcatgga ataagaactt actgaatgga
    11221 tggaatagtt taactgggac atttatttct acgatcaatt cattttgtaa tcaagcaatg
    11281 gtcacgctta gaaactacaa cactcctatg tacaacaatg gccgaacgtg gcagcaaaat
    11341 aatcttaatg gttggaattc attgtatgga tcattcatag cccgtgtaaa tcagcttggt
    11401 aacgattcga ttaacaacct tcgttctaaa agtggtggtt tttacaatgc agggacattc
    11461 ttgttgcaat ctttaataaa cggaatgaat tcgttaggta attctctttc tacaacaatg
    11521 aacaatgtcg ctaatacaat ggttggtggt atgggcaaag gggttaatgg cgtcatatcg
    11581 ggagttaact atgtgcttaa ggaagtcgag tcaagtaaga atatcggaaa ctggccaatt
    11641 ccacaatacg ctaagggaac tgatggacat cctggtggac ttgctatgat taatgatcaa
    11701 aaaggcctag ttcacgaaga atatgtacag atgccagatg gacgtggttt tattgccaaa
    11761 ggtagagacc ttcttgttaa tttgcctaaa ggtgctcagg tcttaaatgc ttctttaaca
    11821 aagaaattaa aggaacgttt aaatattcca cactacgaaa aaggtattgg caatttagat
    11881 attgttgatt tgttagatga tgaaaaaaga atgttagaat tcttgactag caaagttgac
    11941 ttttcaggca ttaatgaacc atggcttgat atgactaaat caggaacgtc attaatgtct
    12001 aaagctgcaa atacaatgct tcaatcaaaa ttaagtgaat tcttcactca tggcaatttt
    12061 gatggtgcag taaatgccaa tggtgtttat caatatttag ttgatgttgc acagaaagta
    12121 atgggtaagt tccccggact tacagtaact tctggatatc gagcaggaga tgcttactat
    12181 cacggaaaac ggcaagctat agacttggct tatccaggta tatctggaga tccgagatat
    12241 acagcagcag ctaattacgc ttttgaaaaa ttcccttcaa aaattgcgta tgtcattacg
    12301 aatggacgtg tacgtgaccg catgggatta tctggaacag ggtcaagcgg acaatggacg
    12361 aattggccag atggcgatca cttcgatcat attcatttaa acggttcgat ggggtctggc
    12421 gatatattca atggaggagt tggaggaagt ggtgttgcac gctggcgttc ttatgtgtct
    12481 aaagcattga aaatgaatgg attaccagct acagcagctt atataaatgc ctggatgtcc
    12541 caaatccaaa cggaatctgg tggtaatgag aaagcaatcg gcggcaatga tgggctcgct
    12601 gaaggcaatg caacaggatt acttcaaacg aaacccggaa cttttgcagc taacgctttt
    12661 cctggtcacg gaaatattat gaacggattt gataacatgt tagcagcaat caattatgct
    12721 aagaaacgtt acggagttgc aggtatgttg caagttatcg ggaaaggaca tggatatgcc
    12781 aatggtggat tgattaccaa agacggacta tatcgagcgg gagaaggaaa taaaccagaa
    12841 atggttattc cattgacaag aaaaacaaga gctattgaat tgatgggtca agcattagct
    12901 tttctttctg gcgatgacaa gaaacgctcc aacactacaa atacagctga taattcagca
    12961 gagcttgtaa ctttgattaa acagcaacaa aaacagcata atgagttaat gatgattctt
    13021 agagcgattc ttggaaaaga tttaagtctc aagtcttctg acattgggca agctgctaat
    13081 cattatatgg gctctgattt gaataaactt cgatatacga atggaggtgt ttgataattg
    13141 ttttacaaat tacagttcaa tcaaaatggg aagttgtttg atccgcaaag aaaagaaaaa
    13201 attgtatgta aagaaatcaa acgtcaagca ccagtgtatg aagtgaatta cgaagatttt
    13261 gaagggacga acggtagcag agaagctaat gctagttttc gtccttttga attagtgctg
    13321 acttttgata tcttttacaa aaataagcat gataaagaac tgctattaac agagttctat
    13381 gagctaattt ttgtcggtta tcaatattac atttcctatg atttaagccc aggaaaaaga
    13441 tttaaagtaa atccaacaaa tttcgaaatt actgaggaag agaacgatta ttctacgata
    13501 gaaataacct ttagtattcc atcagggagt gctgaatcca gcgcaaccac tttaacggat
    13561 ttcaatctag aggaagaatg gcaattctcg caaggtctag tggcggaaga ttacaagtat
    13621 acgcatcaga ctagtcactt cattatttac aatgctggaa gctttgaaat tgatccacgt
    13681 gaacattatc tacggatcgc attagaagga gaatcagaag gaaatgtgac gattttcaat
    13741 aaaacaactg gcgatcgatt tatttactat ccatcacttt ctacgaatct cggacagaca
    13801 ttagtcttgg atggcgtgat tccaaaattg aacggtgtaa gttgtggaat caatacgaat
    13861 cacggtctga tcaatttggt tgagggagtc aatgaaatcg agatccaaaa tattactcgc
    13921 gtgaaatctt catgggattt ccgtttctta tataagtagg tgattgagtg actgagttaa
    13981 ttattcgaaa ttatgaacaa accaaagaag aaatccttgt cggttatgac aagggttctt
    14041 tttatgaaaa ctggcaacaa aatgaaacgt gggagattgg ctttaccgtt accagcaatt
    14101 cgttgaatca agaagtattt gatttagtcg aatacgagtc ttctgttttc tacaacggac
    14161 aggaatttgt gatcaaagaa atgactcgca aagcacttgg acaattgctg acgaaacaag
    14221 tagttgcgac acatatctat tacaccgttc aagatggtta tcagtacaac acagtgacag
    14281 gtgcgaaatc tattagccag ttactcacgc atgtatttag tgcagggagt cgcggcttta
    14341 catgggaagt cattgatcca aacaaaaaat tccttaccgt tgaacaagaa aatttcggta
    14401 acgcgaatta cttgaagctg atcaatgaga ttctatctga ctataatgca gtcgtgattc
    14461 cgaataataa acatctaact ttctatcctg ccagtgagta cggccagcag acggaagaac
    14521 agattcgcta taaatacaat acagatgaag tgtcgtttga tattgatacg tattccttga
    14581 agacgcagat caaaggctat ggaaaattga aggatggtgc aaatactgag aatcctaaag
    14641 atagtgacta tatatttact cccatcactt atacaagccc tgaatcacag aagtggggaa
    14701 tcaggataca agatcctgtt aaagacgaac ggtataccgt atcagggaac atgctcgagc
    14761 ggttaaagac agacttgcaa gactatccaa atatttcggg atccgtaacc ttgaaatgga
    14821 aaatcagtcc caacaaaggc gatcacgtcc cattcattta tgaacctttg aatattaata
    14881 cgtacattca agtggtagga atcaagacgt atccagcgat accaaataag ccaccagaaa
    14941 tcacattgag caacacaaag aaaacaatga cgtcgatact cgctgaaatg gcgaagaaag
    15001 gagtgatttg atggggttat taaaattaat cagtaaccgt atctctacgg aatggaaaga
    15061 gaaatttaat aaaaacattg actaccttaa tgatcttgaa aagaaattgt ctgatcaaga
    15121 caaatcaaca aacagtcgta ttgataatct cgtgcttcat tcaggaggtg attctcctaa
    15181 cgaagtagtg gatgctcggg tgaatcacaa aggcgaaaca ttcgctacgt tacaaggaag
    15241 actgacagac accgaaaaaa aagtttctga aagtgtctct accctagaaa aaaatcaagc
    15301 tgatataaaa gcacaagtcg ctcaattaaa caatagtgta gaaacaatca ttggtggtag
    15361 tgctgactgg ataaatcttt atgtttcagc tgatttggga agcgaccaaa ttggagatgg
    15421 atcagaagaa aaaccatttg cgacaattca gatggctgta aatcagatcc cgttagtttc
    15481 tattcctgga attagaattt gggtagatga tggtgtttat ttggaagatg ttttcataag
    15541 aaatgttagt gctactacta ttcatattgg ccctaaaaat gatacatctg taattgatcc
    15601 atcaaaatca gatatgccag taaaacttcg cagtcttgca ttttatcaat gtaaaggttt
    15661 tttcaaggtc acaggtcttc aatttgtaga tactataaat gcacccaaaa atagtggatt
    15721 aatatatagt ctgatgttgc tacaaggagg atatctttct gtcgataagt gtaaatttgc
    15781 tgaggataac agaaatttaa ccagcgcagc gatttataca gaagggttgt ctgcttctaa
    15841 cgtctacaat acttgctatt tttatagaca aaatattgta gtttatgcca atttaatgtc
    15901 acaagttctt atatcacaac aaacaagcgg caaagaaaac acaacaggtg ctaggagtaa
    15961 ggatgcaatc attcgtggga aattctcagt gggttttgct gataaaaatg aagatgttaa
    16021 agatcttggc ttaatcatta ctaaagggac ggtgttgtcc tgatggcgtt taaaattaat
    16081 gaatcgatta ttgtaattca agcagaagcc actagtccaa acaggacgaa tgttgttttt
    16141 tggtcgcatg atcgaggaac agctaagctt cgaatgaagt tagttcggaa aaacggcatc
    16201 cctcaaagct tacccgaagg gacaactgtt ccgattcgtc tgatgttcag atctgcaacg
    16261 gcagaaggtg gttatggaaa acatgactat ctcgccacca ttgaagatcg tgtaaatggt
    16321 attgtgtcca ttgtgctgga agataatatt ttaggctatg ttggaattgt cgaaggtagt
    16381 gtttatattg atttcccaaa cgaccgctcg ttagatacag ctggtcgttt tacttttgac
    16441 atcaaacgca gtccaatcga tgatagtaca ccagaattgg aagattatta tttcaatggt
    16501 ttcagtcaga ctattgataa aatcgaaaaa attctagctg atggaaagca agagattgaa
    16561 cagaaaatta cggaatctga aacgcagatt gatgcgaaat taaaaaatac aaacgacaaa
    16621 atcacgaaag ccaatcaaga tgtcacaact ctcaatacga atattgataa agcaaatgat
    16681 cgtattgatc aaacgaacca gcaaataagt gatctcggaa agctgaaaaa gatgtactcc
    16741 aacagcatcg atttcgggaa ctatgattat agtggaaatc ctaatttgtt aagtaagcta
    16801 tcatacgact taattgaaaa tcaaaatact tcagctggaa cactttctaa aggtgaaaac
    16861 tcgtttaaat ataataagat atcagctgaa gtggaaggtg gagtagagct atattataaa
    16921 cgaagaggta tagctaactg gctaccatct aataaaacgc ttgtaatgac tgttaagctt
    16981 agagctggag cggactatag tccagttgac ggaaaactta tactgattag atataggtat
    17041 gttgacagtg gaactggcaa gattgtttta gacttaccta ttaacagtaa ttcgataact
    17101 caggaatgga aagagtttag tattactgga actactccaa catttagccc acaagcatac
    17161 catccttgga tacaatttag ggctcaagat gggatacttg gggaaataga aatgagctat
    17221 gacatcaaaa tcgaagaagg ctcaacagct acaccattcc aacctaactt attagcagaa
    17281 ccttacaaca tgtgtcgcga atatcctaac gaaaatattg ccgatcatac agttaagttc
    17341 ccaatcgaat ctggcgacca ccaaatatat caaggttaca cagaagaaga gcttatgata
    17401 ggtcaaacgt atactatcac gcttaaagga acaaaacccg caagtcaaac ctttgtagcg
    17461 tataatcatt ggactgctcg tttaggagaa ctaaagccgg ttgatgggtt gacagacgta
    17521 tggtctctaa cattcacacc aacgaatgtt gtggcgatgc ctaaactttt ccgtgtttat
    17581 cagtatccac gatcaacagt aggcgcatgc caaattgact ggctcaagat tgaaaaaggc
    17641 aacacccgaa cgcccaatat tagtcagttt aaatacttcg gtgaaggctt gaaagatagt
    17701 aacaatccga acgactacag ctgggatatc acacctgaat atgctgaaaa aggcttgaat
    17761 aatacggtta gtctaactga acccgaaacc gttttaggac ttaaaaattt caaagatggg
    17821 gtccagatcg acggagtaga tgtggcaaca gttaaaaact taggtagtgt gttacagagt
    17881 ggatctggtt tgactactat tcaatcagat aagcaaagcg catttgatga attttcatac
    17941 gaattcgaac gtattggtga tagggtattc tttcacgcac gagtaaaaac aaactcgaca
    18001 acagccgtag cttcacatgt gaatctacta gaaattcctt taggatttca gtttcctatt
    18061 ggatggacaa ttgtaggggt tccgttgtcg gttgtacagt ggactacgcc acaaggagaa
    18121 atcagcgctt tggtaatcac tgattcaact ggtaaacaag tagttaaatt tgcaactaat
    18181 cgagtaggaa atcattatat ttcaggagaa tggcgaacag ctgatagtta tccagaaaca
    18241 aagtaggagg gaaataaatg aaaaacattt ggaaatacgg acgtactggc ggagagtatg
    18301 caggaaaagt attggacgat atgcttgtat ccgttcctta cacggatcag ccaccgctcg
    18361 aaggattacg tgctgatggc gaaccgctaa cgattgctga tcagatgttt gatcctaaac
    18421 tgaaccaatg gattgtttta gcgaacacac tggatcacaa cgatttaaac aatctcaaag
    18481 cgatgtacga ggcactggaa cacgagaacg gcgatttaaa acagctcaac gccaaactca
    18541 tgctaagcga tgtagcaatt aaacaggaaa atactgcatt gaaagaaaaa gcggatagtt
    18601 tagcacaaat caattcaaaa atgatgcttg cttcgttaca aaatagcaaa gacatttcag
    18661 aaattaaaga gcaactaaat ccaactttaa agggaggtga gtagtatgtt tagttttagc
    18721 gatgtgaaaa tgatgtatga ttggggctgt tttactgacg atcaagttcg actattcgtt
    18781 ccactatgca ttacagacga agaagcagat aaaatcatta gcaaagaaga gagcgcatct
    18841 taagtgatgc gtttttttgt tggaaagttg gtggaacatg aaagaagaag cgctccaaga
    18901 cgttgtggag agattagtaa gaattgaaac aaaattagac aactacgaat cacttagaga
    18961 aaaggctgat agtgcaaaag atttagcaga taaagcctat tcagtagcac taaacaatgc
    19021 agaagacatc aaggaaatga agaacaataa taaatgggct tggggctata tgattggctt
    19081 aggcattacg atcattggct atttcttgac taaattgtaa aggaggtgag aagaaatgat
    19141 tttaccagat aagtattatc aagtcattaa atggacagtt ttaacagtat tgccagctgc
    19201 atctgcttta gtagccatgt tagggaaagc gtatggatgg aatggaacag atatgatagt
    19261 gttgactatc aatgcagtag caacattttt aggcgttatc actggtgtgt cggcttataa
    19321 tttgaaaaaa taggaggaaa caaatgaaaa agaaaattac tattactgcg atgagcctat
    19381 taacggctct ttttttattg ccaattaatg ggtttgccta tactatcaac aatgaattta
    19441 atttgggcgc aaatgaaggt agctcacaaa tagcaaataa tcagta
//
LOCUS       DADVXM010000046        19363 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.049, whole genome shotgun sequence.
ACCESSION   DADVXM010000046 DADVXM010000000
VERSION     DADVXM010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.049"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(41..637)
                     /locus_tag="KB927_001729"
     CDS             complement(41..637)
                     /locus_tag="KB927_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6840648.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            987..1331
                     /locus_tag="KB927_001730"
     CDS             987..1331
                     /locus_tag="KB927_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBB6840649.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            1332..1751
                     /locus_tag="KB927_001731"
     CDS             1332..1751
                     /locus_tag="KB927_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBB6840650.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1843..2193)
                     /locus_tag="KB927_001732"
     CDS             complement(1843..2193)
                     /locus_tag="KB927_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840651.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(2159..3490)
                     /locus_tag="KB927_001733"
     CDS             complement(2159..3490)
                     /locus_tag="KB927_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBB6840652.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            3745..4311
                     /locus_tag="KB927_001734"
     CDS             3745..4311
                     /locus_tag="KB927_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6840653.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            4456..4543
                     /locus_tag="KB927_001735"
     tRNA            4456..4543
                     /locus_tag="KB927_001735"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4488..4490,aa:Ser,seq:cga)
     gene            4879..5853
                     /gene="bsh"
                     /locus_tag="KB927_001736"
     CDS             4879..5853
                     /gene="bsh"
                     /locus_tag="KB927_001736"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBB6840654.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            6178..8073
                     /gene="asnB"
                     /locus_tag="KB927_001737"
     CDS             6178..8073
                     /gene="asnB"
                     /locus_tag="KB927_001737"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBB6840655.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(8268..8714)
                     /locus_tag="KB927_001738"
     CDS             complement(8268..8714)
                     /locus_tag="KB927_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBB6840656.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8942..9091
                     /gene="rpmG"
                     /locus_tag="KB927_001739"
     CDS             8942..9091
                     /gene="rpmG"
                     /locus_tag="KB927_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6840657.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            9179..9697
                     /locus_tag="KB927_001740"
     CDS             9179..9697
                     /locus_tag="KB927_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6840658.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(9774..10730)
                     /locus_tag="KB927_001741"
     CDS             complement(9774..10730)
                     /locus_tag="KB927_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6840659.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10896..11702
                     /locus_tag="KB927_001742"
     CDS             10896..11702
                     /locus_tag="KB927_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840660.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            11699..12688
                     /locus_tag="KB927_001743"
     CDS             11699..12688
                     /locus_tag="KB927_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBB6840661.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            12685..13689
                     /locus_tag="KB927_001744"
     CDS             12685..13689
                     /locus_tag="KB927_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBB6840662.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13821..14363
                     /locus_tag="KB927_001745"
     CDS             13821..14363
                     /locus_tag="KB927_001745"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBB6840663.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            14383..15081
                     /locus_tag="KB927_001746"
     CDS             14383..15081
                     /locus_tag="KB927_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBB6840664.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            15102..15314
                     /locus_tag="KB927_001747"
     CDS             15102..15314
                     /locus_tag="KB927_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBB6840665.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            15314..16276
                     /locus_tag="KB927_001748"
     CDS             15314..16276
                     /locus_tag="KB927_001748"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBB6840666.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            16294..16689
                     /locus_tag="KB927_001749"
     CDS             16294..16689
                     /locus_tag="KB927_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6840667.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16852..17217
                     /locus_tag="KB927_001750"
     CDS             16852..17217
                     /locus_tag="KB927_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBB6840668.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            17214..19025
                     /locus_tag="KB927_001751"
     CDS             17214..19025
                     /locus_tag="KB927_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBB6840669.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(19087..19254)
                     /locus_tag="KB927_001752"
     CDS             complement(19087..19254)
                     /locus_tag="KB927_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBB6840670.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
BASE COUNT         6264 a         3295 c         3942 g         5862 t
ORIGIN      
        1 ttaacattgt caatcaatga ctaattttac aaaataaata ttatccaaga agaccactta
       61 gatattgacc tccataaatc aaggccatac tatataagaa aatcgacagt ggtttagcaa
      121 tcaaaatgat tagtgtatat cgtttcactg acatgtttgt caatccagcc atcaaacata
      181 acgcatcgtc aggagcaact ggaagaaaaa tagctagagc aaacagcttc tcaaaacggt
      241 tttgattatc cagccagcca atatatttgt tatatgtctt atcgctaatc atggaaagta
      301 tgaatggctt tccataacga cgccctagca gaaaaatgat aatcgaacca atgcagattc
      361 caatatagtt atagataaat ccagcataag ggccaaatat caggacacca gctgcagtac
      421 tgatccctcc aggaatgatt ggaataacta cttgcaggat ttggatgaag acaaaaataa
      481 tcggtcctaa aatgatggaa tcacctacta atcctcttaa cgcattcaaa tctttgaaaa
      541 cacctaaatt aataaaataa atcgtcagcg cgattgatag gcctaatccg ataatggata
      601 tgaaatttat cagttttcga gaggcagcaa tattcattat tcatcaactc cttagaggtt
      661 ctttgttaac tatactttac tagaaaagca actaactgcg ccattttttg atatgacaga
      721 aaacaaacaa ttttgtaagt tcatcataag tataaaagat tgatctcaaa aaaacatcca
      781 actaaagact tatttaataa cttgtttttt ttaaaataaa aaaagcgtta gcaactatgc
      841 ttaaaaagca tatcgactga ataaactaag cattggacag gctgaaagac tacatttaaa
      901 atgaaatgcg aagaaacaat agaaaataaa gttgccttag aaccatagtt gaatcaccta
      961 acagtcgtga agggagaata agagaaatgg cagaaaaaca aaccgcagga cgagatcaat
     1021 taggagattt tgcaccaaaa tttgcagaat taaatgatga tgttttattt ggacaagtat
     1081 ggtccagaga agaattatct gctcatcagc gtagtatcat caccatatct gcattaattt
     1141 caggaggaaa ttttgaacaa ttgccagctc atctgaagat tggcaagcaa aatggcatta
     1201 ctagtgaaga aatagcagaa atcattaccc atttagcttt ttatgtagaa tggccaaaag
     1261 cttggtcagc ttttagttta gcaaaagaaa tctatttaga agaaaatagc gaagataaga
     1321 aagaggcgta aatgatgaca aaacacgaag aaatacacaa tggcgtgatt tttccagcag
     1381 gtgaaaaaaa cgaagcttac gctcaagtat ttaccgggca aagctatctg aatatgttag
     1441 tgaatgatcc cgaagtttct gttggtgtag gtaatgtaac ttttgaacca ggttgtcgca
     1501 atcactggca tgtccataca gacggctatc aaatcttact tgtgaccgga ggagaaggct
     1561 ggtatcagga agaaggaaag ccagcaagac gattaatggc tggagatgtc gtcgtaacgc
     1621 acaaagggat taaacattgg catggtgcga caaaagacag ttggtttgaa catttggcga
     1681 tcactgctgg taattcagag tttttagaac ctgtaacaga tgaagtgtat gaaggattgg
     1741 aaaatcaata atgtcaagct tgaacagctc ctgaaagtag attttaatcg aactttcagg
     1801 agctgctttt ttgattcagt cttttataaa tagaaaatag ggttaataat aggaatgaga
     1861 agcacgtcga aagatcttaa tattgataat cggctgggca tacatgattt ccacgtcatc
     1921 aatcaaacta cctaacagat gataatcttc ccgatcatgt cggggattac ctaatagttc
     1981 ttgatagtag atttccatac tagggtcccg aggattgttc agcaaatcag caagtacatc
     2041 taaatcttct ggctgagttt ctgccgtacc ctgtatctct atgaaaagcc cttcctcagc
     2101 aaattctact ccaatacgta tttcagttat ttcatgggaa tataaataag taagaagctc
     2161 atcgatgatt ctttttgata attctttttc caagtgtctt tttttccttt ctgacagcgg
     2221 taaagttatc tagtatcggt acaaggatac ctgcaacgaa accagttgaa aaaccactgt
     2281 tatatagatt tagtcctccg tgcaaagtgc tgacgttatg gacaagagca atatgtagca
     2341 caccagctat tacaccgtaa aaactgccgt aaaaaccgct tatgggcgca agacctgtcc
     2401 caaacacagc tgcaacaagc atgccagtac tggtgatctc atgaaaagtt ccaaacaaag
     2461 aagcaataaa tattccgact agtatcggaa aactgttttt taaatgacaa ccaaaagcac
     2521 tgaaacccac cgcagataaa atagcaccga tgacaggtcc atttaactga ccgccaacca
     2581 gcaaaacata agaagacagc atcagaccaa ctaagcccat gttgatcaaa gtagcaccaa
     2641 taccagaatt agcaatgaaa tcagttgtca attttccaga tgaatcgaaa atttctcgaa
     2701 tccccgaaag ccgaaaggaa ttataataga aaccaattcc gactgtcagc gaaaaaaagc
     2761 caaaaataat ccaaatgaga ggaaagtgat attcattgaa aaccaatgta ttttcgacga
     2821 ttgaatagct gaataacctc aaaacagcag taaaagtcat cgcaatcaac ccagaggtga
     2881 atccaatatt ataaagtgtg aatccacgat ggaaaactaa agtttgagca gctaagggcg
     2941 gaagaagtat accaattgct atgccagcta aattccccaa taaaatacct atcagtaaag
     3001 gaaaacgcat accaaaagtg atataactaa cgaccggtga taatacgcta ccaaacagtc
     3061 cgatcatgat gtactgagaa aaaggtttat tgacaaatac agcgtataga tacacaccta
     3121 aaatgattga gatagaatta taaaggtttt tgccaaaaaa agagaaaccg gtaactgtta
     3181 gaatcgaagc aaataaggga ccgtttaaaa tcaccttgtg ccgataagct aaaagcacag
     3241 aaagtaaggt caaaatccct acatttatga atgcgcttcc gaaaacacct aaagcaaaat
     3301 aatctgtcaa aagattgctt ggcgaggtaa gaatagttag caatccactc caattatcag
     3361 taggagtatt agaaagcaag ccaataaaaa gaaaaaaaac acctgtaaaa ccaagataaa
     3421 aatactttct tttctgtgaa acgattcgtt tttgaggatg aatataaata acgtcagttt
     3481 cgttttccat tacacacctt ctttttcatt ttctttaact ataacttgaa atgaaagatt
     3541 tggacaacta tcatttaggt caaaactaaa aatgtaaggg aacccattga atttaaccaa
     3601 atttttttaa ttttgcaaaa aaaagttaaa gaagactgaa aaaaatttaa aatataacgt
     3661 tttgagtaaa atgtttgcaa aaaatgctaa aaatagggta caataaaaca acatatactg
     3721 cagtaaagaa gtgggggagt tttaatgaga agaaaagtct ataccaagga tcaaattcta
     3781 aaagctgctt atgatgttgt tgcaaaggaa gggtttaaag gatttactgc gagaaatatt
     3841 gctaaaaaga tggggatttc gacacagccg atttatctgg aattcaaaaa catggaagat
     3901 ttaaaaaata cgttgctgga ttctatcttt gaacaactaa aagaagatgt tttccctatt
     3961 gaacgtactg gtgataaaat cattgatctc ggtttgaact atatctactt tgcaaaaaag
     4021 catcatagtc tttacatggc attgtacatt gatgaacatg gggacggaaa gaaaatgcat
     4081 gatttttcat acaattattt ccgtgaaata gttaaagaag atgaaagata caatcaatta
     4141 tcggatgaat atgtcgatgc tctgcatact ggtacatggg tagcagtgac tggcttagcg
     4201 tcattgatgt catcaaacat catgcatcca acagaagaac aaatcattgc actgatcaaa
     4261 cggacaattg actcgatttt agcattagat aatcctgaaa taatcagata gtgttctatc
     4321 agtatgaatt tgatcggtaa gtccgttggc tgcaaactgt caatggactt ttttgctaaa
     4381 aaaagcgatt tctgttattt atctattaga aataggcttg acatttcgtg aaaaaagttt
     4441 aaaaatagta cttacggaag gttggcagag tggtaatgca ccggactcga aatccggcga
     4501 accggctaat accggcgcgc aggttcaaat cctgtacctt ccttatatca acgattagag
     4561 gttgtgaaga agctgtcctg catcaagtaa taagaacggc caaacaaaaa tagcttttcc
     4621 tattttttcg tttggttggg cttattaccg cagatgcaag cttttgaaca ccgtttgttc
     4681 ggaataaggg gctgtgacaa gacttttgtc acagcccctt attgttgtac ttttaaccta
     4741 caatattttt tgattccccc tgagtactat tttttataaa tgctagtaaa tcaatcttct
     4801 ttggcctttt ttttgataaa aaaaaatact agatgtaaga taaaagtgta aaaacgattt
     4861 gttttaggag ggaaaacgat gtgtaccgca atcacttatg caacgaaaga ccattatttt
     4921 ggaaggaatt ttgattatga gatgtcttat aatgaagtag tcactattac tccaagaaat
     4981 tatcgtttcg attttagaaa ggtaaaaaat ttagataaac attatgcaat gataggaata
     5041 gcagctgggg tatccaacta tccactctat tatgaggcta caaatgaaaa agggttgagt
     5101 atggcaggac tgaattttcc tggcaatgct gattataaag aattacaaga aggaaaagat
     5161 aacgttgcac catttgagtt tattccatgg atactagggc aatgctcaac catagacgaa
     5221 gctaaagaat tattggctac tatcaatcta gtcaatatcg attttagtga aaaactaccc
     5281 ttgtcacctt tacactggtt attagctgat aaagaaaaat cgatagtaat tgaaagtatg
     5341 aaagatggac ttcatttata tgataatcct gtcggtgtgt tgacaaataa tccgccattt
     5401 gattatcaat tatttaatct gaacaattat cgctcgctat caaatggaac accagaaaat
     5461 catttttcaa accagatcag cttgaatgtt tatagtcgtg ggatgggagg attgggctta
     5521 cctggagatc tctcttctgt ttctcgattt gtaaaagcca catttactaa aatgaatgct
     5581 gcatcaggtg attcagaatc tgaaagtatc agtcaatttt ttcatatact aggctcagtc
     5641 gagcaacaaa aaggagtatg cgatactgga gaaggaaaat acgaatatac gatttattct
     5701 tcttgctgta acgttgataa agggatttat tattatcgta cgtatgaaga cagtcaaatt
     5761 actgctgtaa atataaataa agaagacttg gatcgtcatg aattggtcag ttatccagtc
     5821 ataaaagagc aacagataaa ctatgtcaat taattaatga atagatccgt ttggtatcat
     5881 attttctgat acagtcataa ttagacacga tctttaggtc gtgtcttttt ttgctgtttt
     5941 ttttggaaat agcatccact aatatttttt taacacgaag agaataaggt agcctcaaaa
     6001 aagaaaacat ggtaaattag atattgggac tttattttct gtaaaaacag aaactttcat
     6061 cttttgtttt cacgtgacga aattgtaaga gagaaaatat tcgtccgcta tttattctat
     6121 gataagatgc atatgaatga aataaacagt aattttatat taggatgtga aagttaaatg
     6181 tgcggtattg taggttttgt taacgacaag gacaacaaaa aaacaattat taatacaatg
     6241 atggatcgaa tcgttcaccg tggacctaat agttcaggag aatatatcga taaacatgtt
     6301 gctttaggat tcagaagatt aagtattatt gacttagagg gcggtactca gcctatttac
     6361 aatgaagatc ggacaaagat cattattttt aatggcgaaa tctataatta ccagcctttg
     6421 agagaagaat tgattgcagc tggccacgtt tttcaaacac atgcagatac agaagtcctt
     6481 ttgcatggtt acgaagaatg gggaacagaa ttattgcaaa agatccgcgg aatgtttgct
     6541 tttgctattt gggataatga aaagaatgag ttattcggtg caagagacca ctttgggatc
     6601 aaaccatatt attatgcaga aatgaacgga acatttatgt ttggttcaga aatcaaaagt
     6661 tttctgcctc atcctgattt taacaaagaa ttgaacaaag aagcgttgaa accttatatg
     6721 actttccaat attctccatt aaacggcgaa acattcttca aagatgtcta tcgtttgcct
     6781 gaaggccatt attatacgta taaagatgga aaactagaca ttcagcaata ttgggatgca
     6841 gattttgaaa caaaagaaac gcattcccga caagaatgga tcgaaaaaat cgacgaaacc
     6901 gttcaagctt ctattgaagc acatacggtc agtgatgtag aagttggttc tttcttatcc
     6961 agcggggttg attccagtta tgtaacctct gtattgaaac cagatcattc tttctcaatc
     7021 gggtttgatg ataaaaccta taatgaagcg attgaagcca gaaaactaac cgaactattg
     7081 gacttagata atacagcagc agtgatcgac ggagacatgt cgttcaaagc attccctttg
     7141 atccagtatc acttagatga acctgattca aatccttctt gcgtaccttt gtacttttta
     7201 gcaaatcttg cttcacaaag tgtgcgggta gtccaatctg gagaaggggc ggatgaactg
     7261 tttgcgggat accaaacgta tggattccat acgaattcaa aattcatccg tgtgattgct
     7321 caaggattga aaaaattacc aaaaggaaca cgctataatt taggacgtaa aatcggaaaa
     7381 atgaaaaatt tccatggacg gatccattta tatgaatcac ttgctcctgc aaaagaatat
     7441 tttatcggtc atgctcgagt gttcgaagaa tcagaagcat cagaagtgtt aacaccaaaa
     7501 tatcaaacag caccatctgt ggatgaaatc atgactgttc attacgagaa aacagaagga
     7561 atcaaagatg aagtcaataa gatgcaatat gtcgatcttc atcaatggat gccaaaagat
     7621 atcttgttaa aggcagataa actttctatg gcaagttctt tggaagtccg agtaccttta
     7681 ttggatatcg aagtcatgaa attggctcaa caaataccaa gtaagttttt attgaatcaa
     7741 aacaacacaa aagatatttt cagacaagct gcgaacaaac atcttccgga agaatggtcg
     7801 aatcgtgtga aattaggatt ccctgtgcca atcaaagctt ggttgaaaga agaacacggc
     7861 tacgaacaag tcaaagcatt attcgaagca gattttgcaa aagaattttt tgatcaagaa
     7921 aaaatcatga agttgctaga tgaccatcac gaaggacgta aagaagagca aagaaaaatc
     7981 tggacaatct tcagtttctt gacatggtat aaagtctact ttgtagatga aacgattccg
     8041 caagcagaag caatcgacta tgtgactgtt tgatgaaaat caaatatcaa taaaaaagag
     8101 gttttctcct accgtttaac actgagtgat aagaaacaat ttcaaaaaac agctcttccc
     8161 gttttataga tattatgact tatggttcgg agttggcaga ggaacaccat tgtttcgaac
     8221 ataagggggt tgtgacacga ttttcgtcac aaccccttta catatgttca ataatcgatt
     8281 tctttttctt ttgtcccatc ttttttataa atgaacaaag ttgattcttt gttttgtgct
     8341 acttgctttc ctttttcgat tgcttctttt tttgtatcaa aatggttgct tgcctttttt
     8401 gcccctttag atttcacgat ccattgttct tcctcatatt ctacgatcac atctgaatca
     8461 agcagttttc cagcacgagg attcgtatcg tgttcatccg tcttgcttgg atttttttct
     8521 ttttcgaaag ttcgtttttc tgattcacta gcatcttcat accatttttt tgcttgatca
     8581 atggcaattg ggatcgcacg gttatcaggg tacccttcat ctaataatgc atttgcgatg
     8641 tcgattgctt tttttcttgt caatttatct aagtttttca ttgatgcagg aaagtccttc
     8701 atgttccatg gcatattagt atcccccttt attaaaaaac ataatctata taaacaagtg
     8761 taagggtatt tatacaaaaa gaaaaagatt ttgtttgaga agtaaaaccg ttgtatttat
     8821 cgtcaagtag ttttacttaa caaaatcgtg aaaaacacta gcaatctaga aaaaatcatg
     8881 gtaagataat caagtctgag agtcatctta gaggattctt gtaaaaatgg gagggaaaaa
     8941 catgcgcgta aacatcactt tagagtgtac ttcttgtaaa gaacgtaact atctaacaag
     9001 caaaaacaaa cgtaacaatc ctgatcgttt ggaaaaacaa aaatattgcc cacgcgaacg
     9061 caaagttact ttgcaccgtg aaacaaaata atgtttttaa agttctcaat tccttgctgg
     9121 tcaaagaatt gagacttttt ttatctcaaa acatctaaaa tcataaggag cggataatat
     9181 gtttatttcc atgtgggcac aagataaaaa tggtctgatc ggcaaaaatg gtttgttacc
     9241 atggcgattg ccaaatgata tgcgtttctt tcgcgaacat acaatggatc gaattttagt
     9301 gatgggaaga aagacctatg aaggaatggg ggatctttca cttccttatc gccatatcat
     9361 cgtgttgaca acgcaaccaa attttcgcac gaaagaaaat gcggaagtaa tgcattcgat
     9421 cgatgaactt ttgtcgtata gtcaaacgat ctcagaagat atctatgttt cgggtggtag
     9481 tcggattttt caagaacttc ttccttacac tggtcggatc tggcgaacat tgatcgatag
     9541 cacgtttgaa ggcgatacgt atattgggaa tattgatttt tcagacttcg cccttataga
     9601 ggagtatgag gggataacgg atcaagaaaa tctatatgcc catcgttttc aaaaatggga
     9661 aagagtaaaa aatagggttg cttcaaaaga agaataaaat ctatgcgtct agtttgttaa
     9721 taagaaaaaa agcatctcac gactaatcgt gaagattctt tttttagtta aaatcaattt
     9781 agtttttctt tgatatcatt gaccatttcc tgactggcaa taggtccgtt atatagccaa
     9841 ctagattcag gtccgaattg cagtacatga ttgtctgtca ctgctttaag attcttccag
     9901 cttggttcat tgaacatggc agcatctttg tcactgttca caaggatgat gtagtcagca
     9961 tctaattcag ctagcttttc agaggaaaca gcagaccagt cagaagtggc ttttttggag
    10021 acctcttcca ctagatcagg aacaccaaat tccagatcgt cgtatacgat tcttccactt
    10081 gaccgatttt tgctgaccat aaaggctgag ttgttggtca cccacaacac tgcagctgtc
    10141 ttgttctcga ttttatctgc tagttcttct cgagttttct tgatggattt ttgataatcg
    10201 gaaatgattt tttctgcctc tttttctttt gccaaagctt tgccgacatc ttttagttgt
    10261 tcttcccatg tgacatctgt tccgtttttt acaacataag ttggcgcgat tttgctatat
    10321 tgttcgtatt tcccgccttc gacagtagcg gaagaagaaa tcaacagcaa atcaggctca
    10381 aagcttaaca ctttctcata aggaaggtca taagaaatcg ttgggacatc ctttaaatca
    10441 tcttgcagat aatcttgaat ggaaccactg ccaacagtcc actgggcgat aggtttttcc
    10501 cctagtgcaa tcagatagtc ttctaagtaa ctgccgatga tccgtttggg cgcgtttgga
    10561 atctctactt tatgtccaag tgtatctgtg actgtatgag tactattgga tgaagtcgtc
    10621 gaattggcag ttgtagctgt ttctttatct gaagaggggg agcaagcgct cagtactcca
    10681 gccagcagca atatgctaga taatgtgaat acttttgttt ttaatttcat ttctttcctc
    10741 ctaacataat tgagaatctt tctcattggt tattattcct gatatttcga acgctgtcaa
    10801 ccgcttcatt tggctataga tatgaaagta gcgcttgacg aaatgttgaa acagcgtcat
    10861 aattgagaat gattttcagc gaaaggatgg gtgaaatgac gagattaaga gcagctgaca
    10921 ttgcagccgg ctacgaaaac aaaaaaatca ttgaaaacat gtctgttacg attcctgaag
    10981 ggaaaatcac tagtttgatt gggccaaatg gaagtggaaa atctacttta ttgaaaagtt
    11041 ttacccgtat actacctgtg aaatcaggaa agatcattgt caataactct gatatctcta
    11101 catacagttc aaaagaactt gcaaaaaaaa ttacattatt agcacaaact agtgaacacc
    11161 ctacaggtat gacagtagaa gaagtagtat cttacggacg atacccttat caaaaactgt
    11221 tcagtggcat ggacacgcaa gatcatgaag caatcgagtg ggcgttggat gctacaggtc
    11281 tagctggatt tcgtatgcgg gatatcgcaa cgctgtctgg tggacaaacc cagcgtgtct
    11341 ggatcgctat ggcgcttgct caggaaacag atatcttgat cttggatgaa ccgacaacat
    11401 ttttagatcc ggcacaccaa ttagagatcc tacagttatt gactgaaatc aatcaaatga
    11461 aacaaacaac gatcttgatg tcgattcatg acattaatca tgcttcacgt ttttcagatt
    11521 atttattagc aatgaaaaac ggtaagttga tcacagaagg tacacctgaa gaagtgatca
    11581 caaaagagtg tatgaaaaaa atatttgaga ttgatgcaac gattgtcacg cttccaagaa
    11641 caaataaacc agtttttcta acctatgatt tgttgccaaa agagcaggag gatcaattat
    11701 gaggactatg aagaaaaata gactcctgct tttggtctgt tttgttcttt tgattatttt
    11761 ttttgttgct ctttcaaatg gcgcagcgac tgtgggaaaa gcagattttt ggcaggcgtt
    11821 gtttgatttt gatagatcaa aacaaagtca ccaaatcata cgaaatattc gtttgcctcg
    11881 tgtggcggga gcatttcttg tagggagttg ttttgcattg agcggtgcat tgatgcaagg
    11941 agtgacaaga aatcctttag cagattcagg cttactagga atcaacgcgg gtgcttcgtt
    12001 ggcaatggcc cttagttttg ctttttggcc taaagcttct gatttttctg tgtttctaat
    12061 gtcattggca ggttcttttg ctgtaacttt gctcgtattt ggttttttgc agttttcgaa
    12121 aatgggcatg aatcctttac agctgatttt agctggcgta gctattagtt ctttttttac
    12181 tgctatcagc caagcactta cccaattctt taatctgcag caggatcttg ctttttggtt
    12241 tgtaggcgga gctgccaata tcacatggaa acaattagca gtattgtttc ctttatatat
    12301 acttgctgtt ttggtttctt tttcattagg aaaagcaata tctttgattc atttgagtga
    12361 aacacatgca ttagctcttg gaagtcatcc taaacgaacg cggttgattg ttttctgtct
    12421 agttgcagtg ttagcagcca ttgccgtttc gttagtcgga cctgtttcat ttattgggct
    12481 gttggttccg ccagttgttc gcggaatggt tggaacggac tatcgttatg ttctacctgt
    12541 ctctttttta gttggcggtg gattggttat gttggcggat tttacagcga ggatgatcaa
    12601 tccccctttt gaaacacctt ttggattagt cattgcattg attggcgttc cgtttttact
    12661 gatacaagta aggagggaac aacggtgaaa aaaatatatt ggacgttcta tttcttgctt
    12721 tttgtacttg tcatcctgtc tataggtagt ttaatgattg gtacgccttt tatttacctg
    12781 gatcagcttt ttgccacgtt catagggaaa gaatcatctt ctttggcgct gattgttaga
    12841 gaatttcgag ttcctcgatt actgatcagt ttattagcag gagcttgtct tggcgtttct
    12901 ggttatatct tgcaaggagt aacaagaaat gaattggcag attctagtat attgggcatt
    12961 aatgccggag caggattttt agtgatgctt tatttaggtt tcttttcgca ctattcgctg
    13021 ccgtttctat tgctagttgt agcctttcta ggtggtgttt tagctgcttg ctgtgtctat
    13081 cttgcggcct atgatcgaaa tggctttttg ggtatgaatc gaatcttatt gtccggtatt
    13141 gccgttaatg ccggcctttc tgcattaaca ttgctatgca cgatccaatt atctaaggaa
    13201 aattatggat ttgtgaatgc atggttagcg ggatcaatct ggggtgcgag ctggccttat
    13261 gtttgggcat tgcttccatg ggcggttatc ttaattccgc taggaggact ttatgcacag
    13321 aggattggat tgctatcatt tggtcaagaa cgcgcgcaag gattaggcct taacgtggct
    13381 aaaagtcaaa aaatcctttt gttgttagct gttgctttgg caagcggtag tgtagcggtg
    13441 acaggtagtt tatcttttgt aggactacta gctcctcatg ctgcgaagct agtcgtacgt
    13501 aaagaaaata actggacctt tgttctgagc ggtttgttcg gttccatttt tctgcttagt
    13561 gcagatatgg ttgctagagt gattctacca agtggggaag tacctacagg aattttgatt
    13621 gccctttttg gtgcgccata ttttctgtat gcacttttta tcagacaaaa acacgcgctg
    13681 aacagttgaa atttattaaa aaaggaaggc caatcatttc taggtcttct ttttattcta
    13741 tttatgcatt tatttgaaag ttcgattgct atttttcttt ttttcctata ccattttatg
    13801 agagaaggaa gggtgagttt ttggaccaat tgaaagtaag attacgccgg aaaggaatcg
    13861 aaaagctgaa aaatctggcc aaaagtggca agaaaaagga aaaagaacag cgaatctata
    13921 aacagctatt cgccagcgag tactggaagt cagcaaaagt gatagggacg actttatcga
    13981 atgaatttga actggataca cagccggtta tccaacgagc agaaaaagaa caaaagaaaa
    14041 tagttgtacc taaaactttg ccgaaacgtc agatggcgtt ttatgaaatg gatgaacagt
    14101 ccgttcttgt acgttcgagt tttggtgttc ttgagccaca atcagagaag ctctatttgc
    14161 cggagatgat cgatctcctc attgtaccag gtattatcta caatagagcc ggttatcgaa
    14221 tcggttttgg cggtggttat tacgaccggt atttaaataa ttttcataaa aaaacatgta
    14281 gccttgtttt tcgtgaacaa ttgaatgaac aatggcaacc ggagagcttt gatcagaaga
    14341 tccaacaatt gtttattgac taaaatgaaa tgggaggttt tcatgaatta tcaacagcaa
    14401 ataaaattgc gtgcatggtt aagacgaccg ttatggacct atgctttttt agggatacag
    14461 acagcggtct tcctcatgat ggaattattt ccgcgacttg agatccctta ttatgccgga
    14521 atgtatggtc cttatcttgt tcacttcaat gaatggtggc gtttagtgac accaatcttc
    14581 atccattttg gactgatgca tttcgtaatg aactcactga tactgtattt tatggggcag
    14641 caaatcgagg caatctatgg ccattggcgt tttttcttga tttatatgtt cagcgggata
    14701 atgggaaata cagcaagctt tgcttttaac gaagcgaatg ttctgtctgg tggtgcgagt
    14761 acttcgatat tcggtttgtt cggtgcgttg tttatcttag ggtttcattt taaacataac
    14821 ccagcgatcc agcagctagt cagacatttt cttttattta ttgtgttgac atttgttttt
    14881 ggtcttctgg atacctctgt agatgtttgg ggacatgtcg gtgggctaat tggcggatta
    14941 gtgttaggga atgttttggg tctaccgaaa caacagacaa gctattcgat acaccaaagg
    15001 attctttcta cactagtttt tgtatttctt tttgtaatat gtattttact gggtttaaaa
    15061 aaatatggtt tacttgtata atatgaagga agtgcttaaa gatggagagc ttatatgatg
    15121 tacagcagct gttcaaaaaa tttggcatct ttatctatgt gggtgcacgc atctatgaca
    15181 ttgaattaat gactatcgaa ttgcgtaatc tgtatgatag ccgtttgatt gatcatgata
    15241 catacatgac agcgtggcgc atattaaaaa gagagcaccg aattgaagaa agccgaaaga
    15301 aaggaaattt gtaatggaca agaagattat tgggattgat ttaggtggaa caacagcaaa
    15361 atttgcaatt ttaacaccag aaggagagat tcaacaaaaa tggagcatcg ataccaatat
    15421 tttggatgat ggtaagcata tcgttcctga aatcattgaa tcaatcaacc atcgtttgaa
    15481 tttatataat atgaaagccg aagactttat cggaatcggc atgggtaccc caggaagcgt
    15541 ggacagcgaa gctggaacgg ttattggtgc gtataactta aactggacag aagttcaatt
    15601 tgtgaaaaaa ctgatcgagg caggaacagg aatcaaattc gctatcgata atgatgcgaa
    15661 tgttgctgct ttaggtgaac gatggaaagg tgctggagaa aacgatccag acgttgtatt
    15721 cgttactcta ggaacaggtg ttggcggtgg tatcgttgct ggcggaaatt tgattcacgg
    15781 cgtgagcgga gcaggcggag agatcggcca tatcactgtg gatcctgaag ggttcgaatg
    15841 tacttgcggt aaacgcggat gtttagaaac tgtgtctagc gctactggtg tggtacgtct
    15901 aggtcgttac ttggcagaag aatacgcagg agattcaaaa ctgaaagcaa tgttagacaa
    15961 cggtgaagaa gtaacaagta aagatatctt tgaaatggct caagaagacg atccgtttgc
    16021 attgatggtt gttgatcgcg tatgcttcta cttaggttta gcttgcgcca acttggggaa
    16081 tacattgaat ccgtcaagta ttgtgttagg tggaggagta tcggcagcag gagaattttt
    16141 acgtagccgt gtagagaaat attttaaaga atttactttc ccgcaagtaa gagaatcaac
    16201 aaaaatcaaa ttagcagagc ttggtaatga agctggtgtc attggtgctg cctcattagc
    16261 cttgaaattt gcttaaaaaa acggaggcat tacatggttt tatgggtaat taatatcatt
    16321 ttgctattga ttgtgcttgc aatcatcttt tgggaagtct atctacgagt aatggccaag
    16381 cgttcagcaa cgactttgac agaagaagaa tttcgagaag gaatgagaaa agcacaagta
    16441 atcgatgttc gcgaaaaaga tgtgtttgat gctgggcata ttttaggtgc aagaaacatc
    16501 ccttacactg ttttgaaaga ttcattagga tctattcgaa aagaccagcc tgtctatatt
    16561 tacgatcaaa agaaaagctt gagcatccgt acagcaaata aattacgtaa agcaggttat
    16621 caagagattt atttacttaa gggtggatat gacggatggt ctggaaaaat caaaagtaaa
    16681 aaagtataaa acagatgatt gtatgacagc tttaaaaacc gaatcaatca ttagattttg
    16741 accaagatca catgaacggc gcaatggata gttgtgccgt tcattttttt tattttgtgc
    16801 tattatctac atatataagc taagcgaaaa ggcagaaaga aggaaacaac tatgatcaaa
    16861 ttaaaacgtg tttaccttga tgctgaaaaa gaggatggct atagaatact cgtggatagg
    16921 ttctggccac gaggaatttc aaaagaaaaa gcgcagttag atctgtggtt gaaagaaatt
    16981 gcacctagta atgaagcacg caaaactttt gaccatgtac cagaacgatt tgcttcattt
    17041 gcaaagaaat accagcaaga attgattttc gaagaagaaa agaagcaagc tatttttaaa
    17101 ctcagtcaac ttatgaaaga acatccagtc attacttttg tttatggtgc aaaaaatgaa
    17161 catcagaacc atgctgtttt attgaaaaaa tttatcgaaa tggaggcatg caaatgaaaa
    17221 tagggatcat tggtgccgga cctagaggat taagtatagc agaaaggatt ctccataata
    17281 atcaggacag acattctctt gaactttttc ttttcgatcc caatggtcct ggaggtcgag
    17341 tttggcggtt gaatcagcca ccggagttat taatgaattc tgtttctcaa caagtgacgc
    17401 tttttacaga tgaaacattg tccagtggag gattggtaac acagggaccc aacttgtttc
    17461 aatggagtaa aggacctgct acagattata tcgaacagac ggtaaccaaa aataagcaac
    17521 taattataga agaaatcaat cgtctggaaa aagatcagca atctactcga tgtttatacg
    17581 gactctatca acgctggttt ttctcaaagt tgcaagaaga atttccagct tctattcagt
    17641 ttgtttattc tttagtaaaa aaagtcagca aaagaaaaga tggttatctt ttacagacag
    17701 atcagcaaag ctattctatc gatcagcttg ttttagcaag cggtcactgg gaaaatgatg
    17761 agacagaaga agaaagagtg tgggtagact acgcaaagaa aaatgattta ctgtatcagc
    17821 ttccttctaa tcctgcagat gtcgatcttt cgaagatacc gcctaaagaa aatgtctttt
    17881 taagaggtct aggcttaagt ttttttgatt atgtcggatt gtttacagta tcaagagaag
    17941 ggcgcttcga gaacgaaaaa ggaaaacttg tctatcatcc atcaggcaag gaaccgattg
    18001 tatacagtgg atcaagaagg gggctccctt attaccctcg aggaagaaac caaaagcaag
    18061 gcggatcaat ggcatggcca cggttactaa caaaagaaaa cctggagcaa tggcatcagt
    18121 cgggattttt gactggcgaa acattttttg actatctgaa aaaagacgtt gagttgtttt
    18181 attacaagaa aatcatcgaa gaatatcatt tgccgattcc aaagaaaaat tttgagcatg
    18241 attttctctc cctctcttca gaggagtgtc tcggaaagca tccagcacta atcccttata
    18301 gatgggattg gtcgtattta gaaattcctc ttacctatca ggatgagtcc tttgcagaag
    18361 ctagccgagc atttattgaa gggcagataa aagaagcgga aaaaggcaat tgcacaggag
    18421 catttgcttc aacatttgat gcattaaaag actggcgtga tccaatccgg caggctattg
    18481 aatggcacgt tttttctgca aaggaataca aagaaatact atggggatgg tttactcatc
    18541 taaatagctt tttaacgatc ggtccgccag tcattcggac gaaagaatta gcagcactga
    18601 tagatgcggg tatttttcat ttgttcgaac cgccatttga tattcagcaa aagcacaacc
    18661 gctatgttat ttctctacaa gataaagaaa tcagcagtcg ctatttgatt gaagctcgat
    18721 tgccacaaac aagcttttct cgttcaagta atcctgtcat aaaaaatttg aaggaaaaca
    18781 aacttgttcg ccctttttca ttttcagata atacaggaag ttatcattca gaagctatag
    18841 atgttgagcg aggtacgaat cgcgtgattg atgcttcagg ggaaatccag tctgactttt
    18901 attgctatgg aatacctgtt gaaggtgtgg attggctaac tgcagcagta gctagacctt
    18961 atacagatcc atggaatctg agacaggcag ataaaatagc acaacttata ttgactgaca
    19021 aataaaaata cgcatgatga cttatctgtt ctttcacaag tcttcatgcg tgtttttaaa
    19081 taattattaa cgagaaacgc gtttgcgcat tgctttttta cggttttctt cgatcattgc
    19141 ttctttttcg tcaattggat cgatcactgt ttttttcaca gaagcgacca aaccagcaac
    19201 ggcagcggct gttgccagac ttcctactaa tattccagat acaaattttt tcattgaatc
    19261 cacctcattt attatttgtt atatctatta tggaacaaaa gagaaaaaaa ggctagtttt
    19321 acgtttgttt gtaaaccttt gcaaaaaatc cttgaaaatg ttt
//
LOCUS       DADVXM010000047        19238 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.050, whole genome shotgun sequence.
ACCESSION   DADVXM010000047 DADVXM010000000
VERSION     DADVXM010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19238
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.050"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..185
                     /locus_tag="KB927_001753"
     CDS             <1..185
                     /locus_tag="KB927_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6840671.1"
                     /translation="ALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFGK
                     GFGNYDQDIKIKMFYS"
     gene            complement(327..2150)
                     /locus_tag="KB927_001754"
     CDS             complement(327..2150)
                     /locus_tag="KB927_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBB6840672.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(2748..5453)
                     /locus_tag="KB927_001755"
     CDS             complement(2748..5453)
                     /locus_tag="KB927_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBB6840673.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(5759..6706)
                     /locus_tag="KB927_001756"
     CDS             complement(5759..6706)
                     /locus_tag="KB927_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBB6840674.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            6896..7165
                     /gene="rpsN"
                     /locus_tag="KB927_001757"
     CDS             6896..7165
                     /gene="rpsN"
                     /locus_tag="KB927_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBB6840675.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(7341..7703)
                     /locus_tag="KB927_001758"
     CDS             complement(7341..7703)
                     /locus_tag="KB927_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6840676.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(7714..8835)
                     /locus_tag="KB927_001759"
     CDS             complement(7714..8835)
                     /locus_tag="KB927_001759"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBB6840677.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(8851..9201)
                     /locus_tag="KB927_001760"
     CDS             complement(8851..9201)
                     /locus_tag="KB927_001760"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBB6840678.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(9331..10842)
                     /locus_tag="KB927_001761"
     CDS             complement(9331..10842)
                     /locus_tag="KB927_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6840679.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(11164..12516)
                     /locus_tag="KB927_001762"
     CDS             complement(11164..12516)
                     /locus_tag="KB927_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBB6840680.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(12669..13745)
                     /locus_tag="KB927_001763"
     CDS             complement(12669..13745)
                     /locus_tag="KB927_001763"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBB6840681.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            13941..15686
                     /locus_tag="KB927_001764"
     CDS             13941..15686
                     /locus_tag="KB927_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBB6840682.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(15966..16403)
                     /locus_tag="KB927_001765"
     CDS             complement(15966..16403)
                     /locus_tag="KB927_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBB6840683.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(16387..17760)
                     /locus_tag="KB927_001766"
     CDS             complement(16387..17760)
                     /locus_tag="KB927_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840684.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(18082..18570)
                     /locus_tag="KB927_001767"
     CDS             complement(18082..18570)
                     /locus_tag="KB927_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6840685.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(18592..19194)
                     /locus_tag="KB927_001768"
     CDS             complement(18592..19194)
                     /locus_tag="KB927_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6840686.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         5549 a         4081 c         3513 g         6095 t
ORIGIN      
        1 tggcactgag ttatggtaac aaaaaatggt cacttgacga ggctgagatt cctacttatg
       61 aagacacatg gcacttaaga gtcgaggtaa aggaagaagc tgaaaatata ggaggctgta
      121 cattatttgg caaaggattc ggaaattatg atcaagacat caaaatcaaa atgttttaca
      181 gctaaatagg aagaataata acatttcata cgctgttccc atctttaatg gcttatagag
      241 ggcaccttta gctgagaata agacaaaaca gaccctctag cttcaattaa gagctagagg
      301 gtctgttttt gattttaaaa cttggtttat ttcttcaaat ggtagctata ggtgctgaca
      361 acgatatttt cacgccaaga caatcgcaat cttaaccgca aacttgtttg gttatggaga
      421 atattctgcc agcgtctgtt tggtacaaat tgaggaatca acacagtagt tgtatagttt
      481 tgtttcgctg catttttact tacgatatct acataacgga taattggatt ttcaatcgag
      541 cgataagaag agtggacgat tgaaaaacgg acatctggga aatgcttttt aaattctgct
      601 tcgatttctt tttctttttc gacatcttcg tctagcgaaa catgcatcgc aacgacataa
      661 tcaccgatcg aacgtgcgta attcaacgca ccgatattta cccgtgtcac attcccgact
      721 aatacaagaa cggtattccc gtcataatca tgtagttttg catcattttc taaacgaagc
      781 tgttctgcta cttttttata atgatcatgg atcttataaa aaatgaacat aacgattggc
      841 ataatgatga agaaaggcca aatgtcccct aaccgataga caaacaaaat cgcaatgatt
      901 gcatatgaga tgaacgcacc cgtaatattg gcaatcgatt tgcttaacca tctttttcct
      961 tcttttttcc atttgacgac catccctgtt tgagataaag caaatggaat gaacacgccg
     1021 atagagtata acggaatcaa gcgttctgtt gagccatgga aaataaacag caatacgatc
     1081 gaacctagcg ctagtgtgat aatcccattg gaatagccta gtcgatcccc acgatcttga
     1141 tacatgtgag gcatgaattt atcttttgcc agattgtatg caagaactgg aaaagcagaa
     1201 aaaccggtgt tagcagcaac tgctaaaatc agcgctgtag caaattgaag gacgtaatac
     1261 aaaataccat gtccaaagac agctttacca atttgagaca aaacagtgac ttctttttca
     1321 ggaacgatcc cataccaata gttgataaat gtgatcccca cgaagaagaa acctaagatc
     1381 aatgccatca tcgtcaatgt agcagcggca ttttttgctc ttggcttctt aaagaatggt
     1441 acagcattac taatcgcctc caccccagtt aaagaggaag aaccagaaga aaatgctcgt
     1501 aaaatcaaag cgatagaaac acccggcaca gccgctcctg gaagtgcagt agcttgcaat
     1561 ggcacagcac ctgtcacgat attatataaa ccaacaacga tcagtaacga gatcacaagg
     1621 ataaatgtgt acaccggaaa taataggaac gatgcagatt ccctcagccc acgaagattc
     1681 agcatcatca gtagcaaaac gattgtcaca gaaatagcga cttgatgacc gtagagtgct
     1741 ggcaccgctg atgtgatcgc ttcagcacct gctgagacag atactgctac tgtcaacatg
     1801 tagtcgatca ataaagagcc accggaaatc aagccagcat tctttccaag attctcactg
     1861 ctgacgacat atgctccccc gccatgagga taagcatgga tgatttgacg atatgatagc
     1921 gttaatgaaa tcaataaaat aataacaaaa gcggcaatgg gtagcgaata ccagatggct
     1981 gcagcagaca aagcgactaa aacgacaacg atttgttccg taccatatgc aatagatgat
     2041 aacgcatcag acgacaataa tgccaaagca gcaaatcggg ttaatttgtg ctcatcattt
     2101 tcagcagatt ttaaaggctt acctactaac aaccttttta agtaatccaa tttctaaact
     2161 cctttacaca caattttact tcaagtttta tagtcgaaaa tttatagtaa acaagatgtt
     2221 atagtacgct cactgacctt aaaagtcaat aaactttaag aaaataattg gaaaaaaaca
     2281 gaaaaatatc aagcgctttt tcaaacgctt taatacagca aaaatctaac atttttttat
     2341 gggctttttc tttgaattct ataataaaag gatagaactt gacttagaaa atcaagttct
     2401 atcctttttg atatcttaac ttttggaaga gagatgtaag gctgctttct acccatcatt
     2461 cttactactc gaagcatagc gcagttgtca caacctcttg ataaacggtg tttaaaagct
     2521 tgcatctgcg gtaataagct caaccaaatt aaaaacataa gaagctgttt ttatttggtc
     2581 gttcttatta cttgatgcag agcagctttt ttacaacctc ttggtacacg gtgttcaatc
     2641 agctgaccct cggtattagc tcaaaaaaac ggcaaaatat gaggaactat ttttccattt
     2701 ttttctctaa tactcaggtc aaaacactga tttcacaacc tcttttttta atgaaaaata
     2761 tggctctcat gcgccgcttc tttgaatttc gtcatttttt cttcgatgaa cggatagatt
     2821 gccgttccta cgattccaaa gacaacaaac aaaccgatca tgatccagat tgctttcgta
     2881 gcatttggcc aataaattcc tcctgcagat tcccgtaaca agtttaccgc atgagtaaat
     2941 ggcaagaacg gattgatcat ttggaagaat ttccctgaga cttggatcgg atagttcccg
     3001 cctccgccag agatcgacag tactaagatg ataatagcga tccctttacc gacattatcg
     3061 aataatgcag ccaagacata gacgatcatc atgaacgcta aggcgatcaa gacagcaaat
     3121 gacacgctgt agaccggatt ttggacatct actcctagta agaaaatatt ccctaatgta
     3181 acgatcaagc tttgcgcaat cgccattgtc aaaaatgtca gcatacgagc aacgaattgt
     3241 tctcgtttcg taaaattgtt tcggtctttc tttcctaaat agtattctgt cgtagcaaca
     3301 cttgaaagaa gaacagcgcc gacccacaga catagtgcag tataaaacgg ggtgctagct
     3361 gaaccgttat ttgcgattgg ataaagcgca ttggtttgta gctcaacagg ttgtgtaaag
     3421 aagtcacttt cttttgttgc gtctagtttc aataatttga tgacttcgcc tagatcgact
     3481 tcttgttcgc cttttcggat cgcgtctgct gctttttgga taccagcttt gatatttggc
     3541 cagtcattgt tgatcaagtc cgcagcagcg ttcacagctg tttcgacttc tggcattttt
     3601 tcatttactg ttgtcaatgt accggtgatt tcatttttta gtgctggcca atcattttgg
     3661 ataaaatcag cggccaatcc taatttttgc tgaatgatcg gtaattcatt gttgtatagg
     3721 tctgcccctt cattgatgcc attgacgatg gtatccatat ttccattcag cattgtattg
     3781 gcatcatgga tttcttgtcc aattgcaggc atttcttttt gatatttttc taaaattgcc
     3841 actgcattcg ttacagttgc tttcgttgag ctgagaagcg aatcaaagtc gatctggtcc
     3901 gctttgctca gtgcgccttg tgcagtccca atcgtatcga tgacttggtc tagtagagaa
     3961 gtgacagtgg aactgatttg acctgtattg ataccagcaa tgatgccatt gatattatta
     4021 acaacggcat caatttgatc tagcaattca tcaatagcct tcgtgtcttc attttgaaca
     4081 gctgtgttca aagcagatag gcggttttgc agattgctta gcaagggttt taattgattt
     4141 agctgatcaa taattggctg taatttcgta tttccagcac ttgtttgcaa tttagtcagg
     4201 aactcgacca gtttatcgat tgcattttgt tgttgagata ttccgtcaat aaagccgttc
     4261 aatacattgc tgatgttttt cttttcatca tcagtcagct taccatcttc aatagctgtt
     4321 cttacagtat ctattaacga acctgtcgtt gttgccactt gtccaattga cttcaatgta
     4381 acatctacac tgtttgtgat gcttggtatc gcatctttca gctgagaggc acctgatttt
     4441 gtttggtttg ctagatcact tgcctgattt tctaaatttt tcacatctgg caagatatct
     4501 tgtacttgtt ggatgatcgt caagccttgt tttgcttcat cgattccttg gttcattgtc
     4561 tcttggatcg aagcaaaatc gccgtcgatc tctgctagtt gcttaccggc attttggatc
     4621 tctgggattt tttcttgcaa atcaaggatg atttttgctt gatctttcaa ctcaggcatt
     4681 ttgtcattca atgcaacgac tttttcaccc atctcatcta ctttagggat gtaatccacg
     4741 aattcatttg ctttattcag tttttccttg atttcaggta gttgactttg taattcgagg
     4801 acttgttttg tgtagccgtc gatcgtgtcc aaattttcat ctgttgataa aatcatatct
     4861 ttaactttat tgatacttac taggttcgta tcgatgtcgt aacctatctc attgaatact
     4921 ttcaataaag tcgaactggc tgttttgata aattcatttg tgatttgcga ttggatcgaa
     4981 cttgctcctt tatcggtgat tttcggtgca atcgcattga ttttttcatt taccgtatat
     5041 tcgatttttg gtttcttgat atcaccacta gtaaaactca gcagatcttc tgagaaatcc
     5101 tttggcaagt aaatacctgc gtaatacttt ccggaacgga ctccgtcttc taattgttct
     5161 tttgaatcaa cgaattgcca tcctaattgt ttatttttat gaagcgattc gatgacttgc
     5221 tccccaatgg ccacttcttt accttgaaac tctgctggct tgtctgcact gtaaacagca
     5281 attggcagct ctccagtatt tccatatgga tcccataatg ctttgatgtt aaaccacgca
     5341 tatagcgaag ggatgatcat gatcgcgatg atcagaagtg ttgcaatcgg gtttttgaaa
     5401 atccgtttcc agtcaagcaa atataatcga agcgtatttt tgattgactg catagttctc
     5461 ccccttcttc ttttttcagc tgaattactt taccatgtat ttcatacttt tttcaatcgg
     5521 cttttttcaa aaaagtcgaa tttttggaca tatcacggca attgtctcat tgtaatctct
     5581 tacatattga gaaataatta aggattacag cctttacttt atcatgaaat aaaagggaaa
     5641 gataatttta tgccaaagtt tttatctatt atacgtatac gcaaaaaagc taaaacattt
     5701 tttgtctttg cccctacaaa aatgtttcag cttttttcgt tttttattcc tgtatttctt
     5761 atttttcgaa tgacaggatg attttcccag caggaggatg tccttcaact agctgatgtg
     5821 cttggatgac atgcttaagt gaagcagaca gattcattga aataaaaaca tgaaaggctc
     5881 ctttttggta ggctttgatt atgccagcaa aggcttctgc atctagatat tcctttcttg
     5941 gaacaaacga ttcataaaag ccttcctttt tttgccgcaa atctagatct gggaggtcat
     6001 ttaatgcaac atacctgccg cctggtttca tgatctggat gccggtttct cctttgatac
     6061 ttcctttcgt cgcatcgatt acaaggtctg cctgatcagc aaattgcaga cctggatttg
     6121 ttttatcata agcagcaaat gctgaagctc ctaatttttt taccttttcc tcatttttac
     6181 tggatgcact ggttaagatt cggattccct tttcatggag aagctggatc agacttgacc
     6241 cgaccgcacc tgatgctcct agtatcatta cagtatctgt cggctggatt tccgtcaaat
     6301 ggttgattag attataagcc gtaattcctg gcgtgaccat tccggctgct tcttcccaac
     6361 tcattttatc tggaattttt gctacttttg ctgatggcaa cacgacttct tctccgtaag
     6421 tcccgccgac tgcatggaca gctactcgat cacctacatg aacagttgtg acatctgaac
     6481 caatctctgt cacaatacca gcgccatcat tacctggtac ataagggaat ttcaatgttc
     6541 gtatctcttt catttctcct aaacgcaagg caacatcata aggattcaca ctgaatgctt
     6601 ttatttctac acgaacatgt ccagaaccga cttctctggg atgagcatcg atttcttcaa
     6661 aaacatcttg tgcttctccg taaccgttaa ttgcaaatct tcgcatggtc accatctccc
     6721 tttttcttta agtttacgtt tatgtcttta ttttgacaaa aaaaatgtct tttcgttttg
     6781 gcgcatgatt caaaacaaaa tagttgtctt ttttcgcgta acgtgttaaa ttatttatct
     6841 aaaagcgtaa agattacgat ttacgctaat aaaaaataat tggaggaatt tgttgatggc
     6901 taaaaaatca aagattgcca aagcaaaaaa acagcaagaa acgattgaac gctatgctgc
     6961 tttacgccag gaattaaaag cgcaaaaaga ttacgaaggc ttgcgtaaac ttcctttaga
     7021 tgctcgtcca gaacgattga aaaatcgtga tttaatcgat ggacgccctc gcggatacat
     7081 gcgtaaattc gggatgtccc gtataaaatt ccgtgaatta gcacataaag gtttgattcc
     7141 aggagtaaaa aaagccagct ggtaatccaa gtctggctgt aatgtaaagg aggagggcgc
     7201 atggaccact ccttggatca tcaaaaaaga tacgttcgct tcttctagca gaaatgctgg
     7261 tactagaagc agacgtatct ttttttacgc acagctggtc cttttttata tgtaaaggct
     7321 gcatggttac ttcgctatat ttatttagta acaggagtca gtgcttcgat acccacacta
     7381 attttcaatg ctcggtcaac ttctgccata atgggtcgat ccaaatggca gaccttttct
     7441 ttcaatcttg atttatcgat cgttctgatc tgctccaaca ggataacgga gtctctttct
     7501 attcctgttc cagtagcttt gatcccaatg tgagtcggaa gcttaggttt agccattttt
     7561 gccgttatgg ccgcaacaat gatcgtcggg ctaaaatggt tacctagatt attttgaata
     7621 accaaaactg ggcgtgttcc gccttgctcc gatcccacga ctggagaaag atcagcaaaa
     7681 taaatatctc ctctttttac cataggatcc tccttattct tgatattctc ttggtatccg
     7741 ctgtcctaat ccgcaagcca cttcatagtg gatcgtacct aattgatctg ctatatcctg
     7801 catagtgatt tctttgtctg catttttgcc gataagcgtc acttttgttc cgacaggaaa
     7861 ttcttgaggc aatcggatca tcagttgatc catacataca cgcccaatcg tttcacagta
     7921 gttcccttct accaatagag aaaaaccctg catctttcgt ggccagccat ctgcataacc
     7981 gatcggtatc gttccgatcc actctgcttc aggagtgata tatgtttctc catagccgat
     8041 tccttcacct gctgggagtt ttttgacttg aatcaattca gaaaccagct caagtgctgg
     8101 ctgcaatgga taaacttccg gtagtgcgtg cccagaggga ttaagtccgt acattgctac
     8161 tccataacga atcatattgc cgattgtttc atcatgccat aaagccgttg cactattgct
     8221 gacatgtaca tatcgaggaa gttcgggaag ttttttcagc acttctataa agcgttcttt
     8281 ttgcagattc caatatgtat catctgcctg atctgctgta gaaaaatggg taaataaacc
     8341 ttcccattct aatacacgac tttctttgat gaatgcagct gcctctttta cttcttcagg
     8401 tgtacaaaat ccgatacgac ccatcccagt gtctgctttt agatgaatcg aaagaggcgt
     8461 ctctagctta cttttctcta aaacagcagc tgctgcttgc aaccattccc gtgtacctgc
     8521 agttactgat aaatcatgag caacagctac agtcagtgcg tcgtaaggaa ccatattcaa
     8581 gataaggatg ggctgagtaa atccagcttc tctcaactcg actccttcat ctaaatttga
     8641 aacacaaaag cccgaagctc cacctgcaac tgctgcctca gctgtttcaa tagctccatg
     8701 accgtatccg ttcgctttta ctactgcaaa caattctttt ccttgcggaa gtcttgcaac
     8761 ttcatttgct acattttcag ttatagcttt tttatgtatc actgctttcg ttgggcggtg
     8821 ccaagcgaca accatcgttt ttccttcttt ctagtcttcc aaaataattt gtgcaaaagc
     8881 tgtttcattt gtatgagtaa tactgaccca tacattgcct tcatgaggtg aacgcgtcac
     8941 aacaggctga ccattttcat tttttaaaat ctcgacatct tgaaaggtaa cttttccgat
     9001 cccagttccc caagctttag agaaagcctc tttgcaagcg taacgcccgc ctaaaaattc
     9061 tacttggcga tgaaaaggca aggactggaa tagtttcatt tcatcagagg tcaagattcg
     9121 tgcaatgaat tttggttttt cttcgatcag ccgagtgatc ctaggaagtt cgactgcatc
     9181 gatcccaatt ccttttatca tatgcttttc tcttttcaat aaatttagaa cactctcatt
     9241 ctaccaaatt ataaccattt tgccacaaat aagtccacaa ataacaaaaa tgaaagtttc
     9301 tcttaaaaaa gagaaacttt cattttatgt ttaatcgtta tttgaacgga ttacaaatcc
     9361 gcgtttttta tcattgtgac gtttaccgcc atctttttgg ctgttattat ttttgctata
     9421 accgcctttt gatttgtttc cacgataatt accgccgtca cgacgattac ggttgtttcc
     9481 gccaccacgt ttgccatttt tattgtatcc ttttttctgc attggcaatg ggcgttctgg
     9541 tgtgatcttc actggcactg catcagctgg atcttttgct gtcgttttta gcaaaagtgc
     9601 aactaaatct tgtgcagaat attcttctaa taatttatct gctgtttgca ggtatttatc
     9661 tagaccattt tctgcaagtt ttgtttcgat ttgttcaact gcagcaccta attgaccttt
     9721 gaatgcttct ttttcggttg gtggacgtaa agtcgtcatc cgttttttcg tcaagttttc
     9781 aatcacatgc aagtagtcca tttcatttgg tgtaacgaaa gtcacagaca taccgccttt
     9841 tccggcacgg cctgtacgtc cgatacggtg aacgtagctt tctggatctt gagggatatc
     9901 atagttgtac acatgagtga cacctgaaat atctaatcca cgtgcagcaa cgtctgtcgc
     9961 tacaaggata tctaaatgac cgctcttaaa tgaacgcaat acgctcattc gtttttgttg
    10021 agacaaatcg ccatggattc cttctgcacg gtaaccgcgt gcttctaatc cgcgtgccaa
    10081 ttcgtctaca cggcgttttg tacgtccgaa gacgattgtt aattcaggtg tttgaacatc
    10141 aaacaagcga gtcatgatat cgaatttttc gtattctttt gcgcggacat agtattgatc
    10201 gatcaagtca gctgtcattt ctttcgcttt gatcttcaca tgatgtggat ttttcatgaa
    10261 tttaacgcca atattcttga tagctggcgg catcgttgct gagaaaagta atgtttgtct
    10321 ttgatcagga acttgtgaaa tgattttttc gatatcttcc aagaagccca tattcaacat
    10381 ttcatctgct tcatccaaaa ctaatgtttg aacggttcca agtttcaatg tgtggcggtt
    10441 aatgtggtca agcatacgtc ctggtgtacc cacaacgata tgtggacgat ctttcaagcc
    10501 acggatctga cggccaatat ctgctccgcc gtaaacggct tgtacacgta cttttttgtc
    10561 gcgccctaaa cgatataatt cttcttgtgt ttggatagct aattcacgtg ttggtgcgat
    10621 aactaaacct tgtaattcgt gacgatctgg atcgattttt tctaacattg gtaatccaaa
    10681 tgcagctgtt ttccctgtac ctgtctgtgc ttgtccaata acgtcttttc cagctaatgc
    10741 tagtggaatc gtttctgctt ggataggcgt tgcttcttca aaaccagcgc gttcgactga
    10801 tttcaacaat tctggtgata attctagttc tttaaatttc aaatgaatcc tcctatatgg
    10861 ttgttaactg aggatgtagc ttttttgcta ccccgtcgat ttgttcggtc aaagtgtatt
    10921 gtttcttttt gacagtggcc acgcacgttt ttatccattc ttagcccctg tggcaccacc
    10981 gaaaaatcac tttgcgaagt ttaggcatta gaaaagccaa acgggtcgcg ttcagcttta
    11041 tcattattat gacatctggc ttcaacaagt tgtttctatg gcaaaaccag tccaatttct
    11101 cttcatcttt cggcaatagg ttattctaac atagtttttc gttttctgca agtttacaga
    11161 tttttatttc atttgctgaa gttgttctac cacttcaaat aagcccatgc tgttgctgcc
    11221 ttttagcata atactatctg ttgctgcaag attttgtttg atagcatcaa tcaatttatt
    11281 cttttctttt tcaaaataga acacaggtag ttgggggtat ttttggttca attcttcttt
    11341 tagtgcatgc atttgttccc cataaaggaa aatcatggcg aatttctcag gatcgatatg
    11401 ttcactcatt tgcgcatgca tatttaaaga ctctttccct aattccagca tatctgctaa
    11461 cacagcgatt ctgcgtcctt ttgttggcag atttttaaaa gtatctaata ccagtcccat
    11521 ggctgttgga tttgcattgt agacatcgct caaaatagct gcaccatttc ctgccgttag
    11581 ccattcggtt ctgttttgag tgatagaaac atgggcgagc ccttggcgta tctcaggtat
    11641 ggacagtcca aagaagcgcc cgatcgtata cgcaatcaaa gcattcgtta cattataact
    11701 tccaggcagc gggatcgtaa atgtttctcc ttctactaca aaatcggttt gtgcttttcc
    11761 ttttgctgtc acttccgcat gaacatcgcc atttccaata ccgaatgttg tgactgtttg
    11821 tactaatgtt gccgttaaag gtgtcagcaa cggttcatct gcgggcacaa cgagtaatcc
    11881 gtctgataca agtccgtcag tgatttccat tttggcttta gcgattcctt ctcgcgaccc
    11941 aagattttct atgtgtgctt caccgatcat tgtgattgct gcagcttttg gttgagccat
    12001 aagtgaaagt tccgtgattt cattggcgtg atccatgccc atttccaaaa cgatcttttc
    12061 tgtatcttgg ggcatgtgca aaatcgtgta aggaagacca atattattgt tgtaatttcc
    12121 ttgcgtctta tatgttttgt atttttcaga caagacagac gcggttagat ctttcgtggt
    12181 ggttttacca ttgcttcctg taattgcaac gacttctgcg cctacttttt ccaagtaata
    12241 ggttgccaat tgctgcatgg ctttcaaagg atctgctaca ggaataactg gaaaattttt
    12301 tggagcttgt tcaacaggca agctccaaaa tgaagcagat gctccgtttg tgatcgcttg
    12361 ctggataaat tcatgtccat ctcgcgtacc agcaagagga acgaataaac ttccttcggt
    12421 tatcttccgg ctgtcaaatt cgacattggt aatctttgtc agtgcagagc attcgctgcc
    12481 cacggcttgt gcaatttctt gtattgttag attcattgag atctctccta aaaaaggttg
    12541 tgaaaaaagc gtttggccta aacggcgggt tcgcatgact ctcacttcca agtaaatttc
    12601 tctattcgta tttagaagct agaatgaacg cggttacgca atcactccag cctcttcttt
    12661 atttctcttt attcattttt ttcaaaaaaa gattgacgct gatggtatcg attcattcct
    12721 aactggatca gttcttcaat caaatcaccg tatttcaagc ccatattttc ccataagagt
    12781 gggtacatac tgaactccgt aaatcctggc atagagttta attcattcag gaataattca
    12841 tttttatttg tcaaaaagaa atcgcaccgg ctcaatccgc ttccacctaa catcgtgtaa
    12901 gctaacttcg cgtactcttg cgctttttga taaacttctt ctggcacttc ggctggaatc
    12961 tgcatttcga ttttattatt gatatatttt gcttcataat catagaatgc tacgtctttt
    13021 acgacttcac caggcaaagt cgtccgaacg tcttcatttc ctaatacagc aacttcgatt
    13081 tcgcgcgctt caattccttg ttcaacgatt gctcgagaat catactgata ggctgttgct
    13141 aaagcatttt gcagctcttc tcggttttct gcttttgtaa tgccgacact agaacccata
    13201 ttcgccggtt tgacaaacat cggataaagc aaagaacctt cacattgatc aaatactttt
    13261 ttaggatttt ctttccattg attcttaagt actggtacat aaggaacttg cggcacacca
    13321 gcagcttgta aaatatactt ggtcatgatt ttatccatgg cacatgcact ggtcaatacg
    13381 cctgcgccga cataaggcat attcaatgtc tctaagaagc cttggatcgt tccatcttcc
    13441 ccgtttggcc catgtaaaac tggaaaaacg atggctcctt cttctttgat ttcgcccgga
    13501 ttgatcactt ttcctgtaaa gccttcctct gtctgtccac ttgggtccca tgaaagatgc
    13561 aagacatctt tgctggcagg tttttctgtt agtaatggac ctttgaccca ttgtccttct
    13621 tttgtaataa atacgagttg aacttggtaa taattataat aaatggcatt taaaactgaa
    13681 aatgcggaaa gaatggacac ttcatgctct gcgctgcgtc cgccatatag taaagtaatc
    13741 ttcaaaagat tgtcctcctg tattctaaat cgttcagtga tttactctca tattttagca
    13801 caaaacaaaa ataaacgaat aacttattta taaaaaaacg agccagcttc taaaagaacg
    13861 agcgtcattt attttttgtc agctagatta tttgtcccgt tttttataaa aagttatgat
    13921 aaagaaaagg agggatgatg atggcgcaaa caaatccacg cagccgcttg gcagaaatca
    13981 ttcgagtgtt catcaattac aatgtagtgc caaactttgt acagcaaaaa aatcccgaac
    14041 aggtaaaaaa agcctttgaa gaactaggcc ccaccttcat caagatagga cagatgcttt
    14101 ctgttcgaga agatttgctt tcttctgcct tcactcaaac attcaaaaca ttacaagata
    14161 gtgtacctag cgacacattt tcaacggtca aaaagacgat cgaaacagaa ctttctcttt
    14221 cattatcaga tatattcgat gatttttcaa aatcgccttt tgcctctgct tctatggggc
    14281 aggctcatcg tgccaagctg aagaacggtg acgcggtagt cgttaagatc caacacccta
    14341 acatcgccga agagatccga cttgatcttc aactatttga acgagcgatc cctttgatca
    14401 aatacattcc tgaaactagc gtagttgatc taaaaggggt actccaagaa gtaaaacgtt
    14461 ccttgatcaa tgaaatggac ttcttaaaag aaagtcaaaa tggcgaacaa ttctatcaaa
    14521 agaacaatgg ctggaaagag atccgcagcc ccaagattta tgacgctttt tgttcgaaaa
    14581 aagtgatcgt gatggaagaa atgtctggta aaaacttgaa tcatttaatg aacgccgaaa
    14641 acaaaactga aacttttatc actggaattc aaaacaagca gctgaaacaa gaagttgcaa
    14701 agcttttagt tgagaacttt atgaaacagg tgtttgatga tggttttttc catgctgatc
    14761 ctcatccagg gaatctgcta ttccatgtac taacaaaaga agaacagaca caagctagcc
    14821 gaaaaactga aacagtccat gaaaaagagt tcggttcctt tgcttttcga gcctccactt
    14881 ctgcagaaga ccctgttgcg ccatatacca tcaactacat cgattttggt atgatggggc
    14941 atctttctgc aggacttagg caaaaactca cacaagccgt tttagcgctg tatacgaaag
    15001 atgcttatcg aatcgaaaaa gcggtccttc gactttgtca gcaagaaggc tcgtttgatg
    15061 aaagtcggtt ccaccaagaa ctgacaagtt ttcttgaaca gtattatgat tctcctattg
    15121 atgaaatcaa cttgcaagaa gtattcacac atgtcgtgac gatttgtcat caaaataatc
    15181 tgcagttcga tcgtgatatc acgcttttgc tgaaagcatt tgggacatta gaaggggtga
    15241 tccgcgtcct cgatcctgaa gtttccctca tggaagtcgc ttcgcctttt gctcaacatt
    15301 attttctcac tcatctggat gtagaagata cattgaaaca aagcggatta gacttattgg
    15361 aagggatgaa ggctgcgcct aagatccctc aacagctcca ccatctatta gaaatgtgga
    15421 cttcgggaca aggaaaagtc aatttggaat tgaaaaagca agacaaatta ttgagcagga
    15481 tcgaaagtat gatcaatcgg cttgttttcg gtatgatttt agctgcattg atcgtagggt
    15541 cctccctgct tgtccaagca gcacctgtag aaaacgcaga ggtcgtttcc ttattaggga
    15601 tatttacgta tgctattgcc gcattcgtca ttattttttt ggcaatcgat gcattgatcc
    15661 aaatgtataa gaagaggaaa aagtagaaaa aggttgtgac agaaagaatc agcttcaaga
    15721 aataagaagg ggttttacat aaattgtttc tcaaattttt gtgaaaattc ggcttatttt
    15781 tcgaagaggc tacttctgaa acaccgagaa taaaaaatgt gaaaaagctg ttctgcaccc
    15841 agtaataaga acaatcaaaa agggaacatg gaacacattt atcctgtttc cctgttccct
    15901 ttttgatgta ttcgagcata aataaaatac cttcgttacc tactatcttc tgtacttggt
    15961 aaaccttagt caattgcctt ttttaacgct tgacgaaaag acatatgatc tttctccgta
    16021 aagggttttg gaccctttgt ccttatgcca gcttttctta actttccact atgataacgt
    16081 tgttctagaa gcgtgccgat attcgcttcg tcaaattctt ttccagagtg atggaacact
    16141 cgcacaccct tcggcaatac aagtgaagct aaaccataat cttgcgtgat caaaaagtca
    16201 ttcttcttaa ccataccgac gattttataa tccgcactat cagctccgcg gtctacgtag
    16261 acgatttgga catgattagc gtattctttg gtcgtataat ggtccacact ggtcacgata
    16321 accacgtcaa gaccatagga ttctcctaat tttatgacat cttcttttac tggagaacca
    16381 tctccatcaa tgaatagcct cattcttttt cgccttcttc cataaatgat aaacagttac
    16441 taatccgctc agtaaaagac caacattgat ccattttgcc aagataagca gttgtacact
    16501 ttctatcggc actgattcat ggttcagcgt gatcaataat agatggattg gctctcccat
    16561 ttcttttgct aaaacaaaca aaagcgtcat caataaaaac tggtggatca cactcccttt
    16621 attttgagta gtatacttga caacgatccg gcgatccatt ggaatagctg tatcagtttg
    16681 ataatattcc ttatttagcc agctgcctgt tactacgtgc cagaaactaa gcagaaagac
    16741 acctatcgca aaaccatttg gaatcaagag gaccaataaa gaagaactca gtccaagcaa
    16801 ttgcatagcc aatggagacc atgttaaacg tttcaaaatc catggtccga ctatttttgc
    16861 tgcaatcaag cctgctgcat aaggcaaata cataaaaatc gaaagttttt ctaatccgta
    16921 cagtatgcca acataaaaac tgctaaataa aaaaaggaaa ttccctagca ttccatttag
    16981 aaaagtaaac agatttagcc agcttggcaa cttccattcc ttcttctggt gtcctaaaac
    17041 aaacacgaac aagatgaaca gcagcaagaa accataaata gcaagatcaa aaagcctttc
    17101 atcgaataac aatcgggcat ttctcaaaag aaacaataag ccaaagaata tcaaaaataa
    17161 aacaagctct cgcgtagcta ccagatttct tttgatgtct ttgaaatcca gttcgtaacg
    17221 cggataatga ctaaccgtat ggtaggccat gacgtaaaaa agtgtataaa tagtaaagct
    17281 tgctgcaatc tgagtcggtg caggcaactc aatcgcttga tacaggagaa atagccagat
    17341 agctgcaaat aagtactttt tcccatccat attgataaaa ccttgcgtct tttcgtgaaa
    17401 attgaccgtg gtattagcag gtacaagcca tgctgcactc agccctagca aaacacttga
    17461 aaaataaaat aaaggaaaat aaaatacgcc taatattcca agcaatgaac cagcaccacc
    17521 aatcagcaga gcgatcatca gcaacgtgta actatctaga ccaaatcgta gactgttgac
    17581 taaaaatagt ccagtcatcc gaaaggcata aaacagcgta aatggcaaaa tcgtcagcca
    17641 attatgcgag tctgttagtc ccaaaaataa aagataagga ataaaaataa ccgtgttact
    17701 taagataaag ggcgttgttt gtgtaaaatt acgcccaaat cgtttgagtt tttcgaacat
    17761 gacaatggct ccttaaacag tcttataact aatctgctct tcgattttag cattaaaggg
    17821 gaaataaacc aattttacag aatatattct tgtaaaaaaa aatacagaaa gaagcataag
    17881 cttctttctg catttttacg gtacttgatt actcaagcag acaagccctt ctccacaaaa
    17941 gtcttgcccg acacccctgc atccggcagg tgataaagat agaaatcaat tatcctgtgc
    18001 ctccaaaatc aattaggagc tctgtaaacc agagtccttc tcgacccgtc gcataaattt
    18061 actttaacac agttcctatg tttatgcgag agcttttttc attttataat cgaccatttg
    18121 aaatccttga ccgatatctg aaataagttc ttctgtaatc tcaaatcctt catgcttata
    18181 aacctcgatt gcttgatgat tcccctgatt cactcgcaaa aagatctctc tttcctttgt
    18241 ttgcgcagca agttcttcat accagcgaaa aactgaagaa gtcaatcctt gaccacgtac
    18301 tttatttagc aaatataatt tacttaaata aatttttcca tttatctctt cataagcagt
    18361 gtaaccgaca gtcttttctt cgctttttaa taaaaagtag gacacacctt ctgtcagttc
    18421 tttttgaatc tgtttttttg actgataagt tttcagcatg taatccactt gtttttgacc
    18481 aatgatcggc acaaaagctt ccggccatac ttcttgtatg actgccatca gctcatccag
    18541 ttcattttct gttactttta ttttttccat acacccacgt ccttttttac attataaatg
    18601 accttgcgct tgatggaata aaaagagcat gatcatgcta tacacaccca ccgaccatgg
    18661 tttcaagaaa atcacaatct gcataaattc cctaaaagat aatttcgtca aaccagctac
    18721 tagacagatc aagtcgtctg gcgcaaaggg aagcagcaag gtaacaacta gtactttttt
    18781 aatatctttc gtttttcttg tcagcaattc atcaaatttc tgatactttt ttggcgataa
    18841 aataagctgg acaaaggcta cgccatagta acggacaagc aaaaatccga ttgcttcccc
    18901 aatcactagg ccaatacaac tatataaaag cccaaatcca ttgccaaaca tcagcatgcc
    18961 cgctactgag gagatccctc ccggcaaaat aggaatgatc acttggatca cttgcaacag
    19021 aacaaatatc atcactgcat acttgccaaa ttgctggata aacgcttgca aagacgtgct
    19081 cgatcgaaaa atcccatgat gataagcata aagaatcaac acaaagaaaa aaaacagacc
    19141 aataatgggc atgatctgaa gacatttttg taaaactgat ccttttttag acatctatat
    19201 tccccacatc ttttttcatt tattaaaact gcctcctt
//
LOCUS       DADVXM010000048        18890 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.051, whole genome shotgun sequence.
ACCESSION   DADVXM010000048 DADVXM010000000
VERSION     DADVXM010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.051"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..435
                     /locus_tag="KB927_001769"
     CDS             <1..435
                     /locus_tag="KB927_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBB6840687.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="KB927_001770"
     tRNA            complement(759..842)
                     /locus_tag="KB927_001770"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="KB927_001771"
     CDS             1370..1870
                     /locus_tag="KB927_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6840688.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(2060..2404)
                     /locus_tag="KB927_001772"
     CDS             complement(2060..2404)
                     /locus_tag="KB927_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBB6840689.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(2558..3478)
                     /locus_tag="KB927_001773"
     CDS             complement(2558..3478)
                     /locus_tag="KB927_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6840690.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            3665..4156
                     /locus_tag="KB927_001774"
     CDS             3665..4156
                     /locus_tag="KB927_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBB6840691.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(4180..6555)
                     /locus_tag="KB927_001775"
     CDS             complement(4180..6555)
                     /locus_tag="KB927_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBB6840692.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            6881..7507
                     /locus_tag="KB927_001776"
     CDS             6881..7507
                     /locus_tag="KB927_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6840693.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            7530..8234
                     /locus_tag="KB927_001777"
     CDS             7530..8234
                     /locus_tag="KB927_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6840694.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            8426..9259
                     /locus_tag="KB927_001778"
     CDS             8426..9259
                     /locus_tag="KB927_001778"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBB6840695.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            9456..11384
                     /locus_tag="KB927_001779"
     CDS             9456..11384
                     /locus_tag="KB927_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBB6840696.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            11522..11977
                     /locus_tag="KB927_001780"
     CDS             11522..11977
                     /locus_tag="KB927_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBB6840697.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            12447..12716
                     /locus_tag="KB927_001781"
     CDS             12447..12716
                     /locus_tag="KB927_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840698.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            13116..13370
                     /locus_tag="KB927_001782"
     CDS             13116..13370
                     /locus_tag="KB927_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBB6840699.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(13459..14505)
                     /gene="holA"
                     /locus_tag="KB927_001783"
     CDS             complement(13459..14505)
                     /gene="holA"
                     /locus_tag="KB927_001783"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBB6840700.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(14543..16816)
                     /locus_tag="KB927_001784"
     CDS             complement(14543..16816)
                     /locus_tag="KB927_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBB6840701.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            complement(16809..17348)
                     /locus_tag="KB927_001785"
     CDS             complement(16809..17348)
                     /locus_tag="KB927_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBB6840702.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            complement(17484..17702)
                     /locus_tag="KB927_001786"
     CDS             complement(17484..17702)
                     /locus_tag="KB927_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBB6840703.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            complement(17699..17944)
                     /locus_tag="KB927_001787"
     CDS             complement(17699..17944)
                     /locus_tag="KB927_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6840704.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            complement(18060..18788)
                     /locus_tag="KB927_001788"
     CDS             complement(18060..18788)
                     /locus_tag="KB927_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBB6840705.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
BASE COUNT         5800 a         3655 c         3318 g         6117 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat ttaattaact tataatatag cagacaaaat tttataaaca aagaaacctt
     1981 ttatctcttt tcttctagaa aggataaaag gcttttttgt ttttcctatt tgcttctcat
     2041 agctagtcag ccaagatttc tatcgtatcc ccaacgcaat ccgtgcataa cggctcatct
     2101 tatctgtcgt ccatgctgga taccagacta gtttgacttc tgctttcgtt acttctggca
     2161 cttcttttaa tgcgtcatgg atagattctg ttaaaatatc tgctaatgga cagcccatag
     2221 ttgttagagt catcttaatg actgtttctc cattttcagg attgaattct atatcataaa
     2281 tcaagcctaa attgacgatg tcgattccta attcaggatc aatcaccatt tccaaggcag
     2341 caagaatacg ttctttgatt agttctattt cttgtccaga ccgttcttgg tttgcttcgc
     2401 tcatcgtacg acactcctta acacgatttt tatttatcat actctttttt tagctgcttg
     2461 taaatgagaa tttagaagta agattctcgt ttaaatttat aaaaatgttc ttattagatg
     2521 taatagatta aatttattct aaaataaacc tgattcctca ttttttttgt gaacgatttt
     2581 ttatttctgg caatacgcca gttgttcgat acattttttg ttcgttttca tttgcaaacc
     2641 ggccaaatac tgaatgagtt ggtaaaatat tgataaatgc atcgtcgtcg atttcatgaa
     2701 cgatctgatc aagatcatac atttcgtagc gggtgatgac catcatgatc atgttccctt
     2761 gtttttttga atagccaccg acagacggca gtaatgtcat tccacgtacc atccgttttg
     2821 ctagttcttc tgttacctct tctggcttga cggtaacgat cattgctgtt actttttgat
     2881 gactcgtgtg gatggcatca attacttgag tcattgcata aatggaaata atcgtataca
     2941 aggcactttc ccagttaaag aagaagcctg cgatgactac aatgatacca tttagaatca
     3001 gcatgtagtt tccgactgtt tttccagttg tttgtgaaag tacaagagag atgatatcca
     3061 tcccaccagt tgtaaagccc atttttaaag ataatcctac gccaagacct aataaaacac
     3121 cgcctactag ggcattcatc aaaatattat cagtgatctg tccgactgga agcagcatcg
     3181 tcatcaccga tacacataca acattcacaa aactaaggat cgttgctcgt tttcctactt
     3241 tgagaaaccc taatacaaac acagggatat tcaaaagaaa aataaatgtt cctgtgtcta
     3301 tcttgatatg aaaccattca tataaaagcg aggaaatgat ttgagcgatc ccattcatcc
     3361 ctgcagaaaa gacattggct ggaatcaaaa aataatttaa agcgaccgca gcggtcaatc
     3421 cggttatcaa aataaccact attttcttta atctttcatt tttatgatac gcagtcataa
     3481 ttttactcac aagcacctct cccctacttt ggtattccaa atgtaagaat aacagtttat
     3541 ctattaaaat aaaatacttc gaactcaaat gagaagaatt ttagcaaaca ggtaagaatc
     3601 tgccctaatc ctatgataag atagatgtat ggtaaatatt tatatgtata tcaggagggt
     3661 tcctatggca aaagatgcta gcttcgacat tgtatcagaa gtcaatacag aagaagtaaa
     3721 aaatgcgatt cagcaaacaa caaaagaatt gtccaatcgc tttgacttca aggattctac
     3781 agtagaaatc aaattagaga acagcaatct agttgtattg agcgatgatg atttcaaaat
     3841 cgaacagatc aaagatgtat tatttggtaa gctgatcaaa agaaatgtgc caatcaaaaa
     3901 tatccatttt tccgaatcag aacacgctct aggtggcaaa gctcgacaaa ctgccgattt
     3961 ggtcaacgga atcgatcgtg aaaacgcgaa gaaaatcact acagctatca aaaatgaaaa
     4021 actgaaagta aaagcacaaa tccaagaaga tcagattaga gtgacaggta agaaccgtga
     4081 tgatctacaa gctgtgattg ctttattacg taaacttgac ttaccaatcg agttgcaatt
     4141 cactaactat cgttaatcaa aaaacgaggc tgacgtctgt cattcctcgt ttttttgatt
     4201 tactgcttct tttgataacc aaaaacgctg tattccttct tccaattccc caacacttcg
     4261 tacttctctt gctgtttgcc aatgttgtgg gaataaacgt cgataagaaa aactagaaaa
     4321 tcgttgatct gccaatacaa cgattccttg atccgccatg ccacgaatca ctcgaccacc
     4381 agcttgcaag actttgttca ttccaggaag ctgataagcg taagcaaatc caaggtgttc
     4441 cttctcatca taatatgatt tgatcagttc ctgctcatga ttcatctgcg gcaaacctac
     4501 acctacgatc atactgccga tcaatcggtc ccctctcaaa tcgattcctt ctgaaaaaat
     4561 cccgccaagt acgcaaaatc caatcaatgt ttcagcggga tttgtttgaa attttgttaa
     4621 aaatcgttcg cgttcttcct cattcatgtc cgtttcttgg attagcacat tgctgtcggg
     4681 atattgctgt ctgaatgctt ccaccgcaag atctaaatat tgataagaag gaaagaaaac
     4741 gaaataattc ccgacctttc catcagcaaa agcatgaatc gtctctacta attttgccag
     4801 actgtgttcc ctttttcgat aagtcgtctc taggtaattt gcgatgaaaa cttgctggtt
     4861 tccttctggg aaaggactcg gcagtttgta agccagactt ttttgtcccc ccagtgtttc
     4921 ctgataataa gagagtggtg aaaaactagc agaaaaaaga atactgcttt ttcctttatc
     4981 caacgactgc tcaagaaaca agcttggatc aatacaaaac tcttttacta tcagatcgcg
     5041 atacgttttt tcgactgttg tttcgtagtg atcatcataa aattcactga ccttcaaaaa
     5101 atgaagcaaa tcaaaataat aaggaagcaa ttgttcttgt gatgggtgct caggaaattc
     5161 tgccagccat tctttaattt tttcgcttaa ttgataacct gcctttacta aagattcagc
     5221 cggtgctttt tgatgatgat aatcccaatg atcttctttt gctatttctc ggatcgaatc
     5281 aaattctttt aatagtttgt tgaaacggcg atgaagtttt ttgaattcct ttggtatagc
     5341 ttccttactt cgtttcgttt tttcataaga tagttctgcc gaatacatct ctcgggaacg
     5401 attcaccaaa ttatgtgctt cgtcaatcaa aaacagatag tcctcgtttt tttcatcttc
     5461 aaaaaaacgt cttaaataaa cagttggatc aaataaataa ttgtaatccc caatgattac
     5521 gtcacaccag atactgacat ctaatgatag ttcgaaagga caaagtgtat gctttcttgc
     5581 ataagtttcg atgacttcac gagtgatctg attctcatga ttcaaaagat cccataaacc
     5641 ttcattaatc cgattgtaat aaccattggc atatgggcac tgatctggat tacaggtcgt
     5701 ctcatctaaa aagcagatct tgtctttcgc cgtcaaagtg acacttttta cttcagctcc
     5761 tgtatctttt aatgctgtca tagcatcttc agctacttgt ctagttattg ttttagccgt
     5821 tagataaaag atcttttctc cctcttcttc ccctacagct ttcaaagcgg ggaataacgt
     5881 agagattgtt tttcctgttc cggtaggtgc ttctacaaac aatttctgtt tcgtacggat
     5941 cgttttataa gcagctaccg ctagttcacg ctgacctttc ctatactcat catgggggaa
     6001 tttcaaagcc atcaaagagg cattgcgtac agtgcgccag ttttcttgaa aaacaagcca
     6061 ttctttataa tcttcagtca gctttttaaa aaaagtttct aactgctctc ttgtctgatg
     6121 ttcaaccttt ctcgtgatca cttcttctgc cgtctggaag taagtcaatt gcagatttat
     6181 ttcttgtaaa tcatgttctt gactatagat ataggcatac acccttgctt gatgaaagaa
     6241 aagttccact tgttctggtt ctaaatcttc aaatcgtggt tcggaggttt tgatttcatc
     6301 tatataataa ataccgtctc ttttgaaaat accgtctgca cggccttcaa cgatcaggta
     6361 atattcatct aattgaactg ttgtttttaa aaagacttct ttttcatagt tttctcccgc
     6421 atctttttgg agcttgcggt ggattctcgc tccttctaat gcagtatggt tacttttttt
     6481 acgattgtcg atacttccac gtcgcaaaat aaattctact aagtgccgca cagatatttt
     6541 tgactgtttg atcatttcca ccacctcttt ctctctaaga ttacctgaaa aaacctagtt
     6601 tagcaaaaag agctctcttt ccaaacataa aaaaacaccc tgctgattag gcagggatat
     6661 aggatataga atttggattt ttggatgaat ctaatgtaac aaggacatat taaaatgcta
     6721 tgaaaactta ctttccttct ctttagaata tccaaatact tttcatatag tctgataatt
     6781 cagataagta aagagaaata agtacctgtt tttgtttcct agcaatgaat gcgttatact
     6841 aatggatgaa agaagttttg gctatcaagg aggaatgcac atgcatatcg aaagattaaa
     6901 aacaggaatg attgaagaaa actgttattt ggtctacaac gaagaagcac ttttgatcat
     6961 tgaccctgga gaagatgcgg aacgaatcaa acaagaaatc aaaaaaacaa accaacagcc
     7021 ggtagcgatt ttgcttaccc atactcacta cgatcatatc ggtgcagtgg aacctttacg
     7081 cgcgtattat caaatcccag tttatgtcag cccactagag caaaaatggc taggtgatcc
     7141 gattttgaat ctttctggac tcggtagaca tgatgatatt gctgatgtta ttgtctcgcc
     7201 tgcagaatat gaatttgaaa tgaaaactta tactttagga aacatgtctt ttcgcgtcgt
     7261 ccctacccca gggcattcta taggaagcgt cagctttatt tttgatgatt ttgtcgtttc
     7321 tggcgacgcc ctgtttagag gaagtatcgg tagaaccgat ctgtatacag ggaatttaga
     7381 acaattactt catagtattc ggacccagct gtttgtatta cctgatgaat ttgcagtcta
     7441 tccaggacat ggcgatgcaa cgacgattga acaggaaaaa aggacaaatc cttttttcaa
     7501 tcgttaaaac gacttaggag gagaataaaa tgacagaaac tacactttat atcgtacgac
     7561 acggaaaaac gatgttcaat acaattgaac gagtacaagg ctggtgtgat acacccctca
     7621 caaagcaagg acaagaaggc attcattatt taggtcgcgg gttaaaaaat gtcgactttt
     7681 catttgctta ttctagtgac agtggtcgtg caatcgaaac tgcccgtatt attctaggag
     7741 aacattctaa gggaaaagaa attccttatt ttattgaaaa aaggattaga gaatggtgtt
     7801 tcgggtctct tgaaggtgga tatgacatgg aaatgtgggg tgtgatccct cgtgtattga
     7861 attttaaaac atatgatgaa atgtttacca cagaagtttc ttttgaacaa attgctaatg
     7921 ctgtatacaa cttagatacc gctgggtggg cggaaactta tgaaacattg cgagaccgtg
     7981 tatggacagg atttgaagat atcgcccatc actgcgaaaa aaatggtggt ggaaatgttt
     8041 tagtcgtatc tcatggtttg acgatcgcct ttttgcttaa tctgatcgat cctaaacagc
     8101 ctgttcgtgc tgggctttta aatggcagcg taacaaaggt cacttatgca aacggtcgat
     8161 tttctatcca cggcatcaat gatacgtctt atatcgataa cgggaaaaca catagtcgcg
     8221 actcgtttct ataatgggga tattttaatt tttaccagag aatcataaaa ggcaaagtct
     8281 gaacgagggc tttgtcttct tttttctctt cgtgtactta tctgctttat ttctcaagtt
     8341 tttcttaata ttaaaaaaca gattgggttt ctcaaaaaat aacggtatac tataagatgt
     8401 atcttaattg ggaaggaagg aatttatgtt ttttgcaaat attatcaaag cagtgattct
     8461 cggtattatt gaaggaataa cggaatggct gcccatcagt agtactggtc atttgatcct
     8521 agcagatgaa ttcatcaaac tggatgccag ttcacaattt atgtcgatgt tcaatgtcgt
     8581 tatccaatta ggggcgatct tggctgtcgt cgttctttat tttcacaagt taaacccatt
     8641 ttctccaagt aaatcaacgg tagaaaaaaa agatacgtgg acactttggt ttaaagtgat
     8701 cgttgcttgc ataccagcca tcatcattgg tttgcctttg gatgattggt tagaagcaaa
     8761 tttccacaag ttcttaccag ttgccattgt tttgatcgtt tacggtattg cctttattat
     8821 tgtcgaaaaa cgcaacaaaa acaaaacacc tcgttggact tctctgaatg actttacgta
     8881 ccaagcagct cttcttgttg ggttattcca agtcttggca cttgttcccg gaacatcccg
     8941 ttctggcgca acgatcctag gatctatctt gattggtgct tcgcgttttg tcgctacaga
     9001 gttttcattt ttcttaggga ttcctgtcat gtttggcgca agcggcttga agatcgtcaa
     9061 atatttagct gaagggaatt cattcaaaat ggaagaaact gttgttcttc ttgtaggaac
     9121 attcgtatct tttgtggttt ccgtcttagc tatcaaattc ttactaagct atttgaagaa
     9181 aaacgacttt accgcttttg gctggtatcg tattatcctt ggtatcattt tgattggtta
     9241 ttggtttatt gcaatgtaga aaaaaccaga acacttctct tatttgagaa atgttctggt
     9301 tttttatttt ctttaataat aatcattata aataataaaa acaacatcaa gcttaatcac
     9361 caaatgataa ccattatcgt tctcatttag ctgttattat tatcaattac atttttatta
     9421 tgctatcctt gttttgacaa ggaggtctaa taacgatgac taatcagaaa aaagcttttg
     9481 cagcaacaat cggctgcctt ttatttatga tcttcggttt tatcttcgac cgattctctc
     9541 ttaccatcac cccacttttt tatatcagtg ccattatcat cggtggatat aaacaaacat
     9601 cggaaggctt gaaagaattg tggaatgatc ggacactgaa tgtggattta ttgatggctt
     9661 tagctgctat tggtgcctgt ttgatcggta attactttga aggagcaatg ttgacattca
     9721 tcttttgttt aagcggtgca ttagaggaat acacaactaa taaaagtcaa aaagaaatta
     9781 ctgctttgat gaatcttcaa ccacaaaaag cccaattatt aaaagaaaat ggacaaatgc
     9841 aagaagtaga tgtttctcaa ctaaaggtgg ataacttggt atttgtcgct aaaggagcag
     9901 ctgttccgat agatggcttt ttagaaagca cacaggcaac gatcgatgag tctgcattaa
     9961 gcggtgaatc tgtgcctgta gaaaaatatt taggcgatga gatgtatgca ggaacgctga
    10021 atcaaggaaa tcccatcacg attcgagtaa caaaaacgag ttccgaaact gtctttgcta
    10081 agattatcca attagtagaa gaagcgcaga atacgccaac tcaaacagct tcatttatcg
    10141 aacgaatcga aaataattat gtaaaattga ttttgcttgc tgttcctcta atgatccttc
    10201 tcccccactt tttcctaggt tggagttggg atgaaagctt ttatcgagga atggtattat
    10261 tagttgtggc ttctccttgt gcgcttgtcg catctgctac accagcttct ctagctgctc
    10321 tttcaaattc tgcaaaaaat gggattttaa tcaaaggcgg tatccattta gaaaagcttt
    10381 ctgaattaaa agcgattgcc tttgataaaa caggaacgct cactaaagga aaaccagttg
    10441 taactgacag ctttttcttt gatgaaaagg atttggcaca acaacttctt gttgctatgg
    10501 aacaaaaaac gacgcatcca cttgctcatg cgattttgca atatttcgat tgcacaatac
    10561 ctgaagaaat ccaatactta ccaatagaag aaattactgg ttttggatta caaactacct
    10621 atttaggtgc gcaatggaaa gttggcaagc acgcatatga tcctgagacg atgataatca
    10681 gcaaagagat tgcggaaatg atcgaacgtt tggaaaatca aggcaaaacc gtgatttatc
    10741 tttctaaaga tcagcagtta attgctgttt taggtctgct agatattcca aaagcaaata
    10801 cccaacaagt aatttcctac tttaaatccc aaaacatcca tacaagtatg ataaccggcg
    10861 accattctgg cacagcaaag gccattgctg aacaagtagg gattgaacat tactatgcaa
    10921 gctgtactcc ggaagaaaaa acacaactag tcaaaaaaga gaatgaactt taccaagtaa
    10981 atgcgatggt tggtgatgga gtcaatgatg cgcctgcttt agcagccgct tctttaggtg
    11041 tcgctatggg gcaagggaca gatgccgcta tggatatcgc agacatcgtc ttaatgaaaa
    11101 gcgacttaaa taaatttgtc tacagtcatc ggctatcttt aaaaatgcgg cggatcatca
    11161 aacaaaatat tattttttcg attcttgtta ttctcttgtt gattgcttct aacttcctgc
    11221 aatttttaaa tctacctctt ggagttgtag gacacgaagg aagcacaata ttggttattc
    11281 tgaatggctt gcgtttacta agacctttac ctgatctttc tgattcttca aaaaaatgta
    11341 agtcttgtcc actatacaaa gcgcggctgt cttctgtcaa ataagcaaag tgttttttta
    11401 tgattttgtt tattttatga aaaaaacagc ttatgaatag gtcttgaagg atgaattcct
    11461 acttttgtaa ctttctaaaa acatgttatg attgtttcga agaaagtgag gaatatattt
    11521 catggaaagt tggctttttt taggaattat tttacttgta gcaattttag ctaaaaatca
    11581 aagtctgatg atagcggcag cttttgtttt gattatgaag ctcataccag cctcccgttc
    11641 ctttttccct tggcttcaag gcaaaggaat caatattggg gtgacgatca tcacagcggc
    11701 tattctaatc cctatcgcaa caggagaaat cggtctacgt gatctattag aagcctttaa
    11761 atcccctatt ggctgggtag ctgttttttg cggtgggcta gtggctgtct tatcttccaa
    11821 gggtgtagga ttgattgctt ctgatccaca aatcactgtt gcacttgttt tcggcacgat
    11881 tttaggtgtt gtcttcttaa gaggaatcgc cgccggaccg gtcattgctt ctggtatcac
    11941 ttactgtatc ttacaagtat ttgctttagg aaaatagaac aaattttgtc tattttagga
    12001 gattcttaac acccccaatt tactgatccg tgatatactg acaacgaggt gatacaatgt
    12061 tcgaaaaatt aaagtatttc ataggaacaa tcggctggtt tcttctagcg gtacttttga
    12121 ttctgggctt agcttatcta ttatttcctg atttgataca aaatgtgttt gatactgctt
    12181 tttgattgac ctattaaaac gatatagggg atgctcctgc gatgcagggg ctttttttaa
    12241 tcaatgtttt gtaataattt aggccgtgcc aatgagactt cctatagaat tcgatgctct
    12301 tttttctttt tggctcttct gctctttttt gttatactag attacagtgg acaaaagaaa
    12361 gaatgatcgc atccacttca acgaatatca aaatggaaga attagtgcct gttttcaggt
    12421 tactttgaaa agaaaggaag acgcttgtgg aaacttttga aggtctttta attgatacgt
    12481 acgttttaca agaacagcca atgatgctga ctgggatcaa cttgcagctt gaggaccgtg
    12541 tgatcaatgg cctgcttaaa gatcgctatt tggcaaaata tatcttacgt ttgcccctaa
    12601 ataaatatgt gctggaagta agtggcaaat ggaaccgtcg gaaccagttg gtcataaaaa
    12661 aaatgttgat aaaaaatatc gatgaataca ttaaaataat cggtacacca gaatagcctt
    12721 tactgatcaa aggatactgg ttataaaata actgcagttt cttaatagaa aaacaaagaa
    12781 caacagggaa tcgtatccct tttcaaaaaa aactttgcaa acggttctct ttgttatata
    12841 ataacttagt accaaacatt cccattcaaa ctttgtttaa atagataaat aaaaatctag
    12901 tttggtttga cgctattgcc tcccacaata gcgtcttttt gatttttttc agcttgtact
    12961 atccgttttt actgaaaaaa aatcctaata aaagactgtt aaggaaaaaa acttgtcatg
    13021 ttcatattgc aaagcacgct gcctttaggt ataataatga atgttgaatt atgcggtaac
    13081 acgcgtaaga acttaagtta tcggaggtga aactaatgcc aaacattgaa tctgcaatca
    13141 aacgtgttcg tacaagcgaa aacgctaatg tgaaaaattc atctcaaaca agcgctatgc
    13201 gtactgcaat caaaaaattt gaagatgctg tagcttcagg tgctgacaac gtagatgcgt
    13261 tatataaaga agctgttaaa gctattgata tggctgaatc aaaaggtcta atccacaaaa
    13321 acaaagctaa ccgcgacaaa tctcgtttaa gcaaaaaaat cgctaaataa aagaatcggc
    13381 ttcggccgat ttttttattt gtcaaaaaaa ggacaaaaac aaacgacctt cccgcatgct
    13441 ttgccctcgt ctttcttctt atcgatttct taacaactgc cctgtgcgca aaacgaatag
    13501 ttgaaaactt aattcttttt cgatttgtcc cgttttgatt tgataatcca tctcaactaa
    13561 ttgatcaaac aactgtacca gcaaatgttc atcgaatttt tttacttcct gcatggcaag
    13621 ttttacacga tatggatgga ttttcaatgt ttcagcaata tttgcctgct gataaccaat
    13681 ctttacaaga aattttgtct gtaaaaataa acgtaattga gaaagcaaaa tcgcattaat
    13741 tttgattgtt tcttcccctt gcataactaa atcttcgtat aaacgcaaag cttgttccgt
    13801 cttccctttt aaaatatatt gggtcatgtc aaaaatatta tgttctaacg ttttaggaac
    13861 taattcttct acttctctta ccgtgatttg ctgttgattt tgtccataaa ggaccaattt
    13921 ctgtaactct ctcatcattt tggataaatc taagtcggtc aacctcaaga ataaatcaat
    13981 tgcacttcgt tccattttga ttgaggaatt ctctaaggta ttcatcagat attgacgtac
    14041 ttctttttca ttcaactgtt ggacattgat gataattgct gtttttttca attgtttcgt
    14101 tacttttttc cgttcatcca acttttcata tggcgcaaag aatactaata cagtcgattc
    14161 taatggttct ttcaaataag ccgtcaataa atcagtattt tgttcgattc cattgtttac
    14221 tttttcacct gttaaaaaat aaggattctc tacgaatact aaccgttgat ctccgaaaaa
    14281 cggcaacgtc tctgcttcag ctactacctc atctaaactt gcattttcca tgtcaaaact
    14341 taaaaaattt aagtcatctt cgccctctaa ttggattttt ttgacaattt ctgtccgaac
    14401 ttgatcttgg agaaactttt ctgttcctaa aatcaagtaa caagatgcaa gtttttcttt
    14461 acgtattttt tgtaactctg cttgtatact caaattactc accactttca aaaattatcc
    14521 taccatgagc agatgagaat tactagtcta tcattgtttc cactagccca tgaggatgaa
    14581 aaactggatg ccagcgatag gtgatcattc cttgttgatc cgttcgccat gtttttatct
    14641 gattttcttc tagtgtctcc aatacttcgc tgtgcgggtg accataacga ttatttacgc
    14701 cgcaggatat aatcccatgt tttgcttcaa tatgggaaag aaaatctgtg ttacttgacg
    14761 tacggctacc gtgatgacct aatttgacta catcggcttt cagattagga taaatcaaaa
    14821 gcaattgttt ttccattgct tgattcaaat ctcctaaaaa taaaaagcgc ctattgttat
    14881 attccatcca tagaccaatc gaatcttcat ttcttccctc tcccttttca aaaggagtca
    14941 atacataaag atcataataa ccgctgatcc tgtccccatg tttgatttca atgatctcag
    15001 taccattttt ttgagcttca gataaatgcc tttgtaatgg ctcatttcgt ccagcgcccc
    15061 aaccgatata aatttttttg atagtaaaat gctgagataa cgtgggtaat tctcccacat
    15121 gatccgtatc gtcgtgtgtc aagatgagtt tatcgattac acttatcccc tgacctttta
    15181 gatatggaac gatatttctt tcagcaggag gacgtatcat accttgcgcc cacttttctc
    15241 tttcaaagtg taactgacct ccagtatcga tcaaaatcgt ttcttttcga aaaggacttt
    15301 gcaaaaagat actgtctcct tgaccgacat cgataaaagc gatcgttgaa gaaaagcgta
    15361 aaaatggcaa agtcaaaaaa ataaaagaaa aaagaccaac ataaaacaag tgtttcacag
    15421 gttgttcttt caacctatcc atacaaatca gtaatccgaa aatatacatc ccagatagca
    15481 caaggggcaa acgtcctata atgagagacg accctgaaga aaaatcgatt attcgctcaa
    15541 ataagattaa tccctcttct atcagcaaaa gtaaagtttc cggcagccag cgattgaaga
    15601 gtgtgagaaa taacacacca ggaagaaaaa gaaacttgaa taccggtgca atcagtaatg
    15661 taaaaagact acctaaaata ggccactcat aaaaatgcca tacaatcaac ggcatcgtga
    15721 tcatagtaaa caggacgtga gaggccgttt ttttcaacca atctccatca aaagaaatca
    15781 ggataaacaa aaaactcatg aaaaaactaa gctgtccacc cgcatgaaaa agaaatcgag
    15841 gatcaaatag taaaagaagc caaaagacaa ctgcaaataa gtccatggtg gaataatgct
    15901 tattcagcaa tttgactagc aatcgcaata aaaacagcaa actagcacgc aaaacagaaa
    15961 tagaacttcc tgcaatagaa acataacaga tagttagtag actcaacgga ataatactga
    16021 cgtgtagtgg ccatccgata cgtcgaaata aataatacag ccaccctaaa taaaattgga
    16081 tgtgtagacc cgatagactg aacagatgca gcaaaccact ctccctaaaa atttcttctg
    16141 gttctctgaa tcctgcatct ttatagcccc ataataaaga attaatatat acacttgttt
    16201 tttgcggaaa ttcagattgg acaaaggaga taaaagatcc tctttttctc tgaagccagt
    16261 ttcgccagtg attttgcatg gtgatctgtt caatcttttg aatttggaac cgtccagaaa
    16321 ttctatggtt cctgaagtaa gcttcttggt caaaattata aagattccgc ttttttgctg
    16381 gagagatgaa ctcgccttca gcagtcaatt ctattccctt tcctcggaag ttaagccatg
    16441 ttttcaattc tgcttctgtg tttacttgat aagaaagctg gagcttttgt ttattctctg
    16501 ataaccttcc ttccattgtc aaaaaattac catttgcacg aatcgtatct gtaaatacag
    16561 taatttgcgc agatgttgtt ttttcctcta aaaatgaata ctcttgtagc ctataagaaa
    16621 tggataccgt tatgctacac aaaatacaca agtacgcgat aaaacgtcct tcttttagcg
    16681 aaaaccataa aaaaattccg gcaagaagca aacgataacc ccaattgtca gtgtaataca
    16741 acaaacagat aatcatcgac gtaattgccg gaaaaatcaa ccgatttcga acatgccttt
    16801 ctaaaacgct agacatgttt tcctgttaat tcattttgaa gttttgaaaa atgctgtgag
    16861 tctaaagcaa cttggtgtac agatacacct aattgttcga tcaacgcttg ggcataagga
    16921 tcatttcgat agtcatggag ataattgatc cctttcacac cagcttgcaa caaagccttt
    16981 gtacaggcca aacatggaaa atgtgtgaca tagatttctg aaccttccgt cgggatacca
    17041 agttttgcac actgtaggag tgcattcatc tctgcatgga tcgttcgcaa gcagtgtcca
    17101 tccacgacgt aacacccttc atctatgcag tggacatctc cactgactgc tccattatag
    17161 ccgccagcaa tgatcctttt ttctcgaacg agtgtcgctc ctacttctaa acgtgtacac
    17221 gtactacgta aagataacag tactgcctga gccataaagt actggtccca aggaatgcgt
    17281 tcattatgtg acttatcagt aactttttct ttattcgtat cgcatgcttt tgaagatttt
    17341 tctaacatgt tttatattcc tccgtttttt caagttgatt aaaaagtact cattgcttaa
    17401 acaaaatatt ctttaaatat aacgaatcat cctgtctgac aaaagatcct acccttcact
    17461 gccgaaatga agtccgtcat ccattagccc attataaaaa ttcttcgaat ccatttgttc
    17521 aagaaattcc gtataaaaat cgatacttca caatcatggc gttttgctac ttctgtgaga
    17581 acagagatat attctttgat caacttgtta ttccgatatt tttgttttgt ctcatcgact
    17641 gctggtggcg tgataaagaa agcatgatca gaactatagt cttttttcag ctgaactatc
    17701 atccactgca gattttttgg tacgtttctt tagaaagttg tttatgctct gctagatcat
    17761 tcgtcccaat gagaataaat actttatctg ctgtatagct aagtacatct ttggcaaagc
    17821 gttctcgtag agcttgactg ttattgccgc tgacagccgt attcataata tgaatcccag
    17881 atattttatt ttggagatag acattcagca ttggtttttt taatgtttct ttgcgaacaa
    17941 tcaagctatt tcctatccaa aaatactacc tcctcgtcct gccaagctct tagaattgga
    18001 ttattcttag tatccattag cgtccattta ttgctcgtgc cagtcgattt tgaatcattc
    18061 tatttaattg taacgaagtt ttttagtttt tcaactgtct tttcaccgat accagaaatc
    18121 tcctgcaggt cttccacttt ctggaaggat ccgttttctt ctctaaatcg aatgatttct
    18181 tgcgctttga ctgatccgat cccaggaatc tgctgaagtt ctgatggagt ggctgtattg
    18241 atatttattt tgggaggctc ggaatctgct gtaggctgtt ttccttccga ggatgccaac
    18301 tgatcaagat gttctggcag ctcttcacct acagcaggga tatataggac ttgctgatct
    18361 tctatcttcg cagaaaagtt gattcgatcg ctatccgctt cttctaataa tccacctgca
    18421 cgctttagta catcatagac ccgttcttct gaagaaaagg aatagatacc aggctccttc
    18481 acacttcctt tgatatcggt gtacatgacc tttggacgag catcctcttc tacatcgttt
    18541 ccttcagctg atggatcttc tccactggaa ctaaacgaag aaagtatttc ttttgcagca
    18601 gtctcttctg tttctctata aaatagcaaa tttgataata aaaaaccact tgcgatacaa
    18661 aagataagaa ctatcataga catccaaatg atcaatttgg gtgaagctag tattttcttg
    18721 ctgatttttt ctatcattgt tcttttttca aagaatgacc agtaaaaatc attcattact
    18781 cctttcattt aaaattgaag aaacagtgag ctctggcaaa atcgtccctt caacatctaa
    18841 ttacgtcaat tttttctttt gtttttattt ttatcgtgaa gatttttgac
//
LOCUS       DADVXM010000049        17819 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.052, whole genome shotgun sequence.
ACCESSION   DADVXM010000049 DADVXM010000000
VERSION     DADVXM010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.052"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..188
                     /locus_tag="KB927_001789"
     CDS             <1..188
                     /locus_tag="KB927_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6840706.1"
                     /translation="EHSNGLLRKDGLPKEMDFNQVNQGFISSVASKRNHIPRKSLNYQ
                     TPLEVFLSYVNGKFCLA"
     gene            complement(366..2363)
                     /gene="tkt"
                     /locus_tag="KB927_001790"
     CDS             complement(366..2363)
                     /gene="tkt"
                     /locus_tag="KB927_001790"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBB6840707.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2465..2716)
                     /locus_tag="KB927_001791"
     CDS             complement(2465..2716)
                     /locus_tag="KB927_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBB6840708.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2863..3486
                     /gene="lexA"
                     /locus_tag="KB927_001792"
     CDS             2863..3486
                     /gene="lexA"
                     /locus_tag="KB927_001792"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBB6840709.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3666..3884
                     /locus_tag="KB927_001793"
     CDS             3666..3884
                     /locus_tag="KB927_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840710.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4173..4685)
                     /locus_tag="KB927_001794"
     CDS             complement(4173..4685)
                     /locus_tag="KB927_001794"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBB6840711.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4699..6996)
                     /gene="recJ"
                     /locus_tag="KB927_001795"
     CDS             complement(4699..6996)
                     /gene="recJ"
                     /locus_tag="KB927_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBB6840712.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7138..7581)
                     /locus_tag="KB927_001796"
     CDS             complement(7138..7581)
                     /locus_tag="KB927_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBB6840713.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7582..8370)
                     /locus_tag="KB927_001797"
     CDS             complement(7582..8370)
                     /locus_tag="KB927_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6840714.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8367..9308)
                     /locus_tag="KB927_001798"
     CDS             complement(8367..9308)
                     /locus_tag="KB927_001798"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBB6840715.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9485..10072)
                     /locus_tag="KB927_001799"
     CDS             complement(9485..10072)
                     /locus_tag="KB927_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBB6840716.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10293..11600)
                     /gene="obgE"
                     /locus_tag="KB927_001800"
     CDS             complement(10293..11600)
                     /gene="obgE"
                     /locus_tag="KB927_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBB6840717.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11903..12913
                     /gene="gap"
                     /locus_tag="KB927_001801"
     CDS             11903..12913
                     /gene="gap"
                     /locus_tag="KB927_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBB6840718.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12998..13933)
                     /locus_tag="KB927_001802"
     CDS             complement(12998..13933)
                     /locus_tag="KB927_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6840719.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            14119..15078
                     /locus_tag="KB927_001803"
     CDS             14119..15078
                     /locus_tag="KB927_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HBB6840720.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(15164..16258)
                     /locus_tag="KB927_001804"
     CDS             complement(15164..16258)
                     /locus_tag="KB927_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6840721.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16447..17208
                     /locus_tag="KB927_001805"
     CDS             16447..17208
                     /locus_tag="KB927_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6840722.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17323..17763)
                     /gene="fabZ"
                     /locus_tag="KB927_001806"
     CDS             complement(17323..17763)
                     /gene="fabZ"
                     /locus_tag="KB927_001806"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBB6840723.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
BASE COUNT         5139 a         3876 c         3117 g         5687 t
ORIGIN      
        1 atgaacattc aaacggactc ctccgaaaag atggactacc aaaagaaatg gacttcaacc
       61 aagtcaatca aggattcatc tcatccgttg cgtccaaaag aaaccatatc cctagaaaat
      121 cactaaatta ccaaacacca ttagaagttt ttttgagtta cgtaaatgga aagttttgtc
      181 tcgcttaatt tgacaaataa tattctcaag aaacacaaac taatccgaag aattctttgt
      241 tttgtcattt aaatgtaaca tagccgaaaa cgaaaagtaa tattgattta ttcttctaac
      301 acataaagaa cagctgtctc caacttgcag acagctgttc ttatcagtca aacaattgct
      361 tggatctatg atagttgatt gtacgtattc acgacatttt ctactgtaaa tccaaattct
      421 tctaaaattt tagtgccagg ggcagatgca ccgaaatgat cgattgtaat cgttgcgccc
      481 tctgttccta cgtagcgttc ccatccaaat gatgcagcag cttcgatagc cacacgtttc
      541 ttcactgatt taggaagtac actttcttta tattcagaag attgtttttc aaagaggtca
      601 aagcttggca tagaaacaac agaaacatct ttgccttttt cagccaattc tttttgagct
      661 ttcacagcca aatcaacttc agaacctgtt gcaatcaaaa taccttctgg tgtttctcct
      721 tgtgatggag aaagaacata cgcgcctttt ttcaccattt catctgctac ttcttttgta
      781 gaaggcaata ctggaaggtt ttgacgactc aatacaagga tagtaggcgc atctgttgtc
      841 tccatcgcta ctttccaagc agcacgtgtt tcatttccgt ctgccggacg aatcacttga
      901 acaccaggca tgcagcgaac agatgctagt tgttcaatcg gttcgtgcgt tggtccgtct
      961 tctccgacag caaccgagtc atgtgttaag acgtaaacaa caggagtatg ttggattgct
     1021 gctaaacgaa ctgctggtct tagataatcg acaaagacaa agaatgttcc accgtagata
     1081 cgagttccgc catgaagttg gataccattc atagccgaag ccattgcaaa ttcgcggaca
     1141 ccgaaccaga tgttgcgtcc ttcataatgt tcaggagtga aatctttatc tgcagccacc
     1201 attgtattat tggaacctga caagtccgct gaaccacccc agaagcttgg tatagctttc
     1261 gataattctt ggatgacttc tttacttgaa acacggcttg cttgactgct tccaacttca
     1321 taagttggca attctgcatc ccagttttct ggtagtttgc catcaaaagc atcttcaaat
     1381 tgttgtgcta attcaggata agctttttta taattggcaa acatttcatt ccatgcatct
     1441 tcagcttttt gtccttcttc tatcatcgtt tgatggaagc gggcagctac ttcttctgga
     1501 acagtgaaat ctggatactc ccaaccataa acttctttag ccatcttgat gccatcttca
     1561 ccaagaggag caccatgaac agcagatgtt ccttctttag gagcaccata gccgatgact
     1621 gtttttactt cgatcaatgt tggtttgtct gtttcagctt ttgcttcttc aatcgcttta
     1681 gagattgctt ctaggtcatt tccgtctttc actaagatat gttgccagcc atatgcttca
     1741 tagcgagcac caacgttttc tgtgaaagct tttgaagttg gaccgtctag tgaaatatcg
     1801 tttgaatcgt ataaaacgat caatttccct agtttcatat gacctgccat cgaacttgct
     1861 tcttgagata ccccttccat caagtctccg tcaccgcata ttgcatacgt atagtgatcc
     1921 atcacattaa agttttcttt gttatacgtt gctgcaaggt gcgcttctgc cattgccata
     1981 ccgacagcca ttgcaatccc ttgtcctaat ggccctgtag tggcttctac accatctgta
     2041 tgatgtactt caggatgtcc tggtgtttta gaatcccatt gacggaattg tttcaaatca
     2101 tcgattgtca cttgatagcc agctaaatga agcaagctat acaacattgc tgacccatgt
     2161 cctgccgaaa gaacgaaacg gtcgcggtca gcccagtttt ttgatgtcgt tggatttact
     2221 ttcaggtgtt ttgtccataa cgcatatgcc ataggtgctg cgcccatcgg caatccagga
     2281 tgtcctgagt ttgctttttg gactgcttca atacttaatg tacgaattgt gttaacgcca
     2341 agttggtcaa ttttgtcaaa caaaataacc cctcctatta atttaggttt tttttacctt
     2401 tatttcttac actttcattc tataagatgt cacacgaaaa agcaatcttt ttcagtattt
     2461 tttactaaaa gttgtcattt cggttgtgta agcctttttt cttttggatt tcttttaatt
     2521 tttccggggt cacgtcattg ccctcaggat cgacgacttt cattccttcg atatgatgac
     2581 gcataccgga acgaaaagct tccaaatact ctttgcgcaa gttgatttgt tcttgttctt
     2641 cggcttttga gagaccattt tccttctttt tacgtgcaag ttcattgatc cgctctattt
     2701 tttcaggtga cagcatgctc agccctcctt ttactctcct tcatattata taaaaactga
     2761 aaaaaaaaca actagataaa ctaaataaaa tacgaacatt cgtttgattt agcgcttttt
     2821 atatggtact atttatttat caagtgaaag aaggtgtacc ttgtggcccg acaaactgaa
     2881 tcaagacaaa tcgaagtctt acgatatatc catgaacaag taacccaaaa aggatacccg
     2941 ccgactgtcc gtgaaatcgg ggaagctgtt cagctttctt ctacttctac tgttcacggt
     3001 catcttgcac ggcttgaaaa aaaagggttt atccaaagag atccgacgaa acctcgtgca
     3061 atcgagttga caaaacaagg tttagaaaag attgggattc gtccaacaac tattccagta
     3121 cttggcgtcg taacagctgg agaacccatt ttagcagtag aggatgcttc agacttcttt
     3181 ccaatccctc ctaatctttc ttccgaagaa ggcagtctct ttatgctgac aattcgtgga
     3241 gatagtatga tcaatgctgg gatattggat ggtgacaacg tgatcgttcg gaagcaagaa
     3301 actgctcaaa atggcgatat tgtcattgca atgactgccg aggacgaagc gacttgcaaa
     3361 cgattctata aagaaaaaaa ctttttccgt ctgcagcctg aaaacgactt gctcgaacca
     3421 atcatcttag atcaagtatc tatattagga cgagtagtag gactttatcg tagtcatatc
     3481 tattaattgc tactaattaa aagaaaactt tttaaaaaga gtttgagacg ttggtctcaa
     3541 actctttttt cgcccgggtt cttcttcttt caaattttta tcacttccct ctttacaaac
     3601 cgaacaaata ttcgtatact aaatatacga acaattgttc gcataaatta aagaggtgag
     3661 aattcatgaa atcaatgaga cgtcttggct tagtattaac tgttttgttt ttaggtatta
     3721 ttattggtaa tttcggcata cgtccagctt tacttgtgtt tgttccgtta tttactttgt
     3781 ggttcatgtt gtgggatgaa aagaagtacc gtcaatctga gcggcgcaga attcatgaag
     3841 atcatttcta tcatgagccc tactacagat ccaggcaatc ataataagga ttgactgcta
     3901 attattcaaa agacaagaag ttaaactttt acgggggtgt gacaaaaatc ggtcacatcc
     3961 tttttttcga ataaacggtg ttctaaagcc agtttttcgg tattaagtca aattgcggaa
     4021 aaagtgattt tttaaacttc tactggtctt tgcttgtttc catttataaa aaaatagcga
     4081 ccctcaaaag tcagatagag aatctgactt ttgagggtcg ctttaaaatc gcttctttaa
     4141 gaataacatc aagaatagct tcttttttct gcttaatatt ccattaatgt aatgatgtca
     4201 tatcctttga ttttgtcgcg tccatggaga tccatcaatt cgatcaaaaa tgcgcagcct
     4261 acgactacac cgcctaattg ttcgatcagt tcgatcgtcg ctttgattgt tcctccagta
     4321 gctagcaaat cgtcacaaat cagcacacgt tgacctggtt taatggcatc cttatgcaat
     4381 gtcaatgtat ctgttccata ttctaatcca taagtcactt cgatggtttc tcgaggtaac
     4441 ttcccttttt tgcggactgg ggcaaaaccg actcctaact cataagcaac aggacatcct
     4501 acgatgaatc cacgggcttc tggcccaact accatatcaa ttcgtttttc ttttgcataa
     4561 tttacgattt gtttagtagc ttcccgataa gcgtcaccat ctgccatcag tggggaaata
     4621 tctcgaaaca caattccttt tgacggatag tcgggaatac tggcaatata atcttttaaa
     4681 tccactcttt gtttcctcct aggttgttaa ccatttcttt atggtaggaa tatcgctcaa
     4741 aagcaaaaat tcctcaactt tgattttatt gagccgtcgc tggtataatc tgctctcagt
     4801 caaaggatga ctttctgggc tagcgacttt ttgtaaaaca ccgttctcta ttgtaacaaa
     4861 tttcaattca aaaaacacct gtatcataaa aattaataat ttttcaggga tacgcaaata
     4921 ttgagctatt gcttttattt tatgacgtat atcaattcgt tcttgagaat ggatcaattt
     4981 aaacaatttt gcgtactgtt ctcttgtgcc taccccattc aaataggcct catcaggtga
     5041 aatccccatc agataaacac gattgaatga ataagaccga aaaacttctt tcagatccgc
     5101 taaatcatct ggacaatcca taacaactag agagtttggt tttctttttt caattattgc
     5161 ctttacagaa tctagtcctt cgaaaacaat cgcagcttcc tggataatct caggcacgaa
     5221 tttcaacgtc gaagaatcaa atgctaaata aaggctacct tccgacgttc ggctctgttc
     5281 acggaaacgt tttgcccgcc aatcaaatac ttgcagacca cccacagaaa aatcagatac
     5341 catcagctgc ggtttcttac gcccgttcca ttcattgatc gaaagctttc ctaccacatc
     5401 tacctgatta ttcagcagtt cttcttcttg agtaccaaaa ccaaaagcga ccgcatcaag
     5461 ctgactcgat gcatcggaaa ggacaaattt cagatgctgt tggtttgctc cgattctttt
     5521 gatattttct gcttggactt gtcgaaataa aaactgaggc aaaggattat ccgtaccaaa
     5581 tggcgccaat agtttcagct catcaattcg ctctactgtt acttcatttg gcagcaatac
     5641 ttcatcaatt ctcaactcag gccctctcat caagtcaatt tgatgatcga ctatatattg
     5701 gttcatcttc tcctgtagta tagtgacatt ttcacttggc atcgttaaac cgactgctgc
     5761 atgatgtcct ccgaagtaag taaataaatc tcgcatctgg tcaagcattt caaaaagatt
     5821 caaggcttca atactacgtc cagatccttt agctgatcca tcttctttta aagtaaggac
     5881 aagcgttggt ttacccgttt cattcattat tttcccagca acaatgccca aaacgccttc
     5941 atgccatcct cggtttacca atagatggat atgattctcc ttattgacca tcgctaatgc
     6001 ttcttgtgtt atctgctcta cgattgcttt tctttcttca ttgatctcat tcaatttttt
     6061 tgcttgaacg gatgcttcct cttcatcaaa cgtcgcaagt aacgagacgg caggacgtgg
     6121 atcgcccatc cgaccgattg catttagtct gggagcaatc gaaaaaccga tcgttgtttc
     6181 gtctgcgtcc ctcattttta cgccgctttc ttcaaatagc gcctgaagtc ctatccgttc
     6241 tgaatgatga atggcatcga ttcctaatga aacaaggatt cgattctcat cagtcaatga
     6301 aactaaatcg gcgatcgttc ctatcgctac taaatccaaa aattctgcag gcggttcttc
     6361 caataatgca gaagctactt tgaatgctac tccgactcct gccaaatctg gaaatggata
     6421 gtgccccgct ggatgacgag ggtgaacaat cgcataagcg tctggtaaat tctcaggtag
     6481 ttcgtgatga tctgtaatga tcacgtctac accagcttgc tgagcgtatg ctaccgcatc
     6541 atttcctgct accccgttat caacagtgat gatcaactgg attccttctt cgatcttttc
     6601 ttggtatacc gattggtttg gtccataccc atgctcaaat cgatttggca ggaatacttc
     6661 tacttctgca ccaagtaatt ccagtgtttc tttcattacc gttgcactgg tgatcccatc
     6721 tgcgtcataa tcaccgtaaa cgaggatttt ttctccactg attacagctt cttggattcg
     6781 gctgattgct ttatccatat cgtgtatcag atacggatca tgtaattctt gttcctttgg
     6841 atgtaaaaat cggttgatat ccttttcctc atggtaacct ctttgccaca gtaacttacc
     6901 gacaaatgga gataatttca gttcacggat catttggaga aaggattcag aaggctctgt
     6961 ctcgcttaac ttccaatcaa aatttgcttg tctcactttc tcactcctaa cttagttatt
     7021 atagcaaagg aaatcagcaa aaaaaagcag aaagaaagaa taaaaacaga tcagatccgc
     7081 tagacagatg ttcagcagga cctgatcttt tgtacgacca tttatgaaat atccctatta
     7141 gtcaaaataa ttgaagcttt gtttgggcga ttgagttttt tgttcttccg gcgctttcaa
     7201 ttgactgatt tgtgcggttt tcgcttgtaa ctccgcctga taagcagctt ccaactccgc
     7261 acgttcgttt ctaaactcgc gttgctgttc ttcttttgct tcttcaattt tcttttgaag
     7321 ttctgtttga tattctgaca tttcctgagt cagctgtttg atttgctttt tttgctgcca
     7381 tagtgttgcc gaagcagtca aaaatacaat cagtgcacca atcagcgcag aaccgatgat
     7441 cactaagatc aatggcgcag aaaaggaagt gaagccaaaa cttacaggaa catttttatt
     7501 gttcaataca gcaaaaagaa caataatcaa aactaaaaca aatccaagaa tcacattgct
     7561 ttgctttttc aattccttca cctacttttt gttaaaaatt ccgctggcta aataatcacc
     7621 aatcgttgga aacagcgtat aaaattttga tgcaacttct aaaataaacg gttgattgat
     7681 ttcccgtttt ggatgtctca tattgcggac gatcattttt gccaacttgg caggttctaa
     7741 aacgatttgt ccgacttttt ccaaatagct tccgcttgga tcagccttat cgaagaaatt
     7801 tgtctcgatt ggacctggat tcactgtcgt aacagctacg ccaagtggtt tcaattctaa
     7861 tcgcaaagcg ttggagaagc caaggactgc aaatttcgtg gcagaataaa ccgttgattt
     7921 tgcagttgcc atttttccag ccatagaggc gatattaatg atatgacctt gtcttctttc
     7981 tgccatatcg atcgcaaatt tttgtgtcaa aaccatcatt cctaagatgt tgacttcaaa
     8041 catatcgtat gcttttccaa ggtcgaatgt aaggaagtct tcgaaaatcc caaaacccgc
     8101 attgtttacc agaatatcga cgcgcccgac ttcttccatc accttttcat ataattcgtc
     8161 cacgctttca ggattgctga cgtctacctt gaaagcataa gcctctttgc cgctcaagcg
     8221 tctgcactcg tctctgacac cttctacaaa tgccattctt cgtgcgcaac ttataacgat
     8281 tgctccttgc tttgctgctt cataacagat ttgtgcgccc agaccgcctg aactacctgt
     8341 tactaaaaca actttatctt ctaaattcat gcctcttcct cctcgcgaaa tggaatctca
     8401 atgctatcaa aatctttcat aatcgtcgtg ttttcaaaca cttcttgtgc ttctttttca
     8461 agctctaaag ctgcttttcc taaatatctc gcactgatat gagtaagtag cagccgtttt
     8521 gcctgcgctt cttttgcaac ttcagcagct tgatgagtcg tggaatggaa atagttgtgc
     8581 gccattcttg cttcatcttt attaaatgtg ctttcatgta ccagaatatc gctattttcc
     8641 gcaagcacaa cggaattatg tgtttttctc gtatcgccta aaatagtcac gattcgtcct
     8701 tttttatctg gacctacgaa atcttttcca ttgatcgtcc gcccatcttc tagttggatc
     8761 gtttcacctt gcttcagttt gccgtacagt ggtccagctg gaatacctaa ttcttttaga
     8821 cgatccacct gcaattctcc tttatgatca tgttcaacca cacgataacc aaaactgtcg
     8881 atcccatgat ttagtttttt tgtataaaca gaaaattgct gatcagtaaa aatcggggct
     8941 gtttcattta gctcaatgaa tttcagcgga taacttaaac gcgtttgcga aatacctaaa
     9001 gagactttta tgtattcctc tatccctttt ggcccgtaaa tctctaatgg cgtatcccca
     9061 ccttgaaatg accggctgct gatgagcccg ggaagtccaa aaatatgatc gccgtgtaaa
     9121 tgtgtaatga aaattttacc gatttttctc ggacgaatag tcgttcgcaa aatctgcatt
     9181 tgcgtgcctt cgccacagtc gaacaaccaa acttcattgc gctcgtctaa aagtttcaat
     9241 gctatacttg tcacatttct atgttttgca ggaacacctg cacctgttcc taaaaattgt
     9301 aattccataa tctacctgac tttctttaag ttcctcttta attttagggt aaaaagaagg
     9361 gataatcaac cgtaagtcga gaatgggttc aaattaaaaa taacgttcta aagcgatagc
     9421 gttttctttg aaaattacta taaaaacagc agcgaacccg tttgagatcc tctgctgttt
     9481 tttattaatt tgaagatcca gaactttcat tgtcgttgga agtttgcgga tgtttgtcct
     9541 tccaagtctt ttgtgcagct tctttcgcat gattttcagc ttctttcgca tcatgcacat
     9601 ctttttcgac atcttcataa tccaagcgag taatttctcc gcctaattcc atcattacca
     9661 attgattcag tgggcgattg tcctcttcat cagcaatcaa gatcagtcct gtagctcctt
     9721 caccgatttt atttcctaca aagtcgaaca cggtctgggc atcttttatt tctttggcat
     9781 cttgtgtcgc accgatcatt cctccggcaa accatcctaa taaaatccct agcggaccac
     9841 ctaatacacc aaccaacatt ccgattaatc cacccgtaga agatttgtta ttaccggtaa
     9901 agtcgataaa atcttctatt ttgaattgat gtgtcccatt aggatcatgg ctgacaactg
     9961 ccatctgttc tcctttaatc gaacgaacag catgtaactt tttgatttct gaaaatgcct
    10021 gatatgcctg gctttctact tgaaaattta aaatgattac tcgtttgctc attaaaaacg
    10081 cccctttcat accttcttgt tatttatttt acctttaatt gtaaaataag aaaagaaaag
    10141 cactcttttt ttccaataaa atagggctgt gacaaaagtc gtatcacagc tcctttttcc
    10201 gaataaacgg cgttcttgaa gctgatcact tctgtcacaa cctcccttaa atctgaatct
    10261 atattttttg gtatttgttt ttatttgctt gcctattcga caaattcaaa ttcaaactca
    10321 ccgatacgta caaggtcgcc atctttcgca ccgcgtgccc gaagagcttc atccacaccc
    10381 ataccacgta attgacgagc aaaacgcatc actgtttcat catgatcgaa attcgtcatt
    10441 tggaataatt tttcgatctt ctcaccagat aagatccacg ttgcatctga atcacgatcg
    10501 atttggaact caggaccttc tggattgaat ccatagtgta cagtttcttc ttccagttct
    10561 tcttcgtaca atgggaattc tggcgttact tctaacaaat ctgctgtagc attcaataac
    10621 gcgtccaatc cttgtcgagt cactccagaa attggaaata ctgggatgtc atcagcaaat
    10681 tcatcttctt tttccttgtt cagctgttct ttgaatttca ctagattttc cggtgcatcc
    10741 ggcatatcca ttttgtttgc cacgatgatt tgcggacgct ctagcaagcg taagttataa
    10801 gtagataatt ctttgttgat ggcaagatag tcttcataag gatctcgtcc ttccatccca
    10861 ctcatatcga tcacatgtaa aattactcgt gttctttcga tatgacgaag gaattgtgta
    10921 cccagcccaa caccttgcga agctccttca atcaagcctg gcaagtctgc tgcggcaaaa
    10981 cttctgccat cacttgtagt aaccattcct agattaggta cgagcgtcgt gaaatgataa
    11041 gcgccgattt ttggacgagc agatgaaata acggatagta aagtcgattt cccgacagat
    11101 ggaaaaccta caagtccaac gtctgccaat actttcaatt ctagttcgat ttttcgctct
    11161 tgtcctggtt caccgttttc agcaatttcc ggtgcaggat tccgaggaga ggcaaaacgg
    11221 atattccctc gtccaccgcg tccacctttt gccacaacta gtgtttgacc attttcaatt
    11281 aaatctccta aaagagcacc agtctccgca tctcggacag tggttccttg tggtacttta
    11341 acataggtat cttctgaacc acgaccgtgc atccctttac tcatcccatt ttcacctggc
    11401 tgcgctttga aatggcgatt gaaccgaaaa tccatcaatg tacgtaaccc ttcatcgacg
    11461 atcaagatga catcgccgcc acgaccaccg tctccgccag ccggtccgcc gtcaggaacg
    11521 tatttttcgc gacgaaatgc aaccattccg tctccgccct tgccagcttt cacatcgatc
    11581 gttacttgat ctaaaaacat ggacataatt aagtcctcct attattcatt tatttatttg
    11641 actgcctgaa tttccacaat aaacaaaagt cttacttatt ttatcggtga aatctgattt
    11701 tgtctatcat ttcagcaaaa agattgttta ccttcttctt tttttatcat ttggtaaggt
    11761 ttccaacctt ttttctgcta ccaagtataa ttttttgaca aaatattctt tgcgtagcag
    11821 aataacagtg tattaattgt attaattgta ttaattgagg atgccgtttc acagcacccc
    11881 taataaagga ggaacttttg atatgacagt aaaagtaggt attaacggat ttgggcgtat
    11941 tggccgtctg gctttccgcc gcatcaaaga agtctcagat gatattgaag tagtagcaat
    12001 caacgactta acaagtccaa ctatgttagc acaattattg caatttgact ctactcatgg
    12061 tacttatcct ggcacagtta ctgcaacaga agactcaatc gtagtggatg gcgaagcaac
    12121 tcgtgtttat gcagaacccg acgcaagcaa aatcccttgg gcaaaagaaa acggtgtaga
    12181 tatcgtacta gaatgtactg gtttttatac atctgaagaa aaagcaaaag cgcatttaga
    12241 tgctggtgtc aaacgagtag ttatttctgc cccagctggt gctatgaaaa ccatcgtcta
    12301 taacgtcaat gatgatacat tagatgaaaa cgacaaaatc atctcagcag gttcatgtac
    12361 aacaaactgt ttagcaccta tggcttattt cttaaataat gaatttggga tcgaagttgg
    12421 tacaatgaca acagttcatg cctacacttc cacacaaatg ctcttagatg gacctgtaaa
    12481 aggcggtaat ttgcgtgctg ctcgttcagc tgctgacaat actatcccac attctactgg
    12541 tgctgcgaaa gcaatcggct tagttatccc tgagctacaa ggaaaattac aaggacacgc
    12601 acaacgtgtt ccagtcgttg atggttcatt aactgaattg gtttcagtat tgaaaacaaa
    12661 agtaactgct gatcaagtaa acgaagcaat caaaaaacac acagttgaca atccttcatt
    12721 cgggtatgat gaccgtcaaa tcgtttctag cgatgtcatt ggaacaactc aaggttcgat
    12781 ctttgaccca acgcaaacag aagtaacaac tgctggtgat ttccaacttg ttaaaactgt
    12841 tgcatggtat gacaatgagt atggatttac ttgccaaatg attcgcttac tagaaaaatt
    12901 cgctaacttg taatttgata gatcaatcga taaaagaagc ctttgactgg atccagtcaa
    12961 aggcttcttt cttttcatcc cctactttta aactcgttca atgaacatat tggcttaaaa
    13021 attgttggac tacttgctga tatttttcag gatctgtctt gtatgcttcc gcatgctcgg
    13081 ctccttttac aacatacttt tcttttggtc ccttcgttgc acgatagacc ttatctaaca
    13141 tttcaaatgg tacaaatgta tcttcgtctc catgtataaa gagcattggg cgctggtttt
    13201 tcttcaattg ttccactgca tttgcttcac cgaaaaagta gccagcacgg acttttgtca
    13261 ctagactcgt tacttgcata agcggaaatg ctggaagact aaacatatcg tctagctgat
    13321 aagcaagctc atcatgaacg gaagaataac cgcaatcttc aatgattgct ttcacattat
    13381 ctggtagttt ttctccgcta gtcatcataa ctgttgctgc tcccatgctg acaccgtata
    13441 gaacgatttc ttgcgatttt ccattgtttt ctagcacttt gtttatccac tgtacatagt
    13501 ctttacgctc tggccatcca aatccaatgt aatccccttc gctttttcca tgtcctcttg
    13561 catcaggaac aaggacattg taacccatat catgaaacat ctttgcgtaa ttggtcatcg
    13621 tttcagcgtt tcccatatag ccatgagcca caagagctgt tttttcactt ttcgtttcag
    13681 caggaagata aatcgctgat aatttcagac cgtcttttga agtgatggtc caatcgcttc
    13741 ggttttcttt tgaactaaac catttatgtg catccgtttc tttggatgtc tgtgttgtac
    13801 caggtgtatc ttcgtctaaa aagtctttct cagaaggcac aacagcataa ttataaaaat
    13861 aattccctgc aaacactaac gcaacaatca gagctaaagc gacgcctaaa aggattttca
    13921 tccaaagttt cataaatcat ccatctcatt tctctttttt catataacct tgaattagta
    13981 taatcaaaga atctctacta tgcaatgttc atttttataa cccgcgaatt gtaaaattaa
    14041 gttagaaaaa taaaaaggca tttatggtac actcaaattg tatttccgac gaaagaaaac
    14101 aaaggagtgt aaccataaat gacctacaaa catcttacca tagacgaact gacaatgata
    14161 gaatcatatt atcttcaaca taataagccg gttgaaatcg ctaaccgaat gggacgtgct
    14221 atacaaacta tttataatgt agtcaataag ttcaagcaag gcaagactgc tcttgattat
    14281 tggcaccagt ataaagaaaa taagaaaaaa tgtggtagaa aagtcattca attacctgct
    14341 catgaagtag attacattaa agagaaagtc actcttggtt ggacgcctga cgtcattatc
    14401 gggcgaaaag aaaggtctgt ttcatgcggt atgagaacac tttatcgttt attttctaaa
    14461 ggaatatttg atattgacac actaccgatg aaaggtaaaa gaaaacccaa tggccatcag
    14521 gaaaaacggg gaaaacaaca gtatcagcgc tcaatccatg atcgacctga taattatcct
    14581 gatttcaatt ctgagtttgg tcaccttgaa ggtgatacga tcgttggcat tcatcataaa
    14641 agtgccgtca ttactttagt tgaaagatta tctaaagtca ttatcacgat taaacccaac
    14701 ggccgtaagg cattagatat tgaaactgcc cttaatcaat ggttttctcg cttccctaaa
    14761 aacttcttta aatctattac gtttgactgt ggaaaagaat tttctaactg gaaagccatt
    14821 agtaaccaac atgatattga tatatatttt gcggaccctg gaacaccttc tcaacgccca
    14881 ttaaacgaga attctaacgg gattctgcgt cgtaatggac tgccgaaatc aatggatttt
    14941 agaaaagtga atcagacatt tatttccagt gtcagcaatc aacgtaatca tattccaaga
    15001 aaatcattga attacagaac accaatcgaa atatttttga gctatgtaca agaagcattt
    15061 tattctagct taatttgaca aatcataacc tataaaaaaa caaaataaaa aagcagaaat
    15121 aactggctat ttctagcgga ttatttctgc aataactaat tatctatttt ttattttcaa
    15181 ttaatttaaa gcttgaccat ggtttcaaaa agtcaaggag gaataattcg tcatcggaga
    15241 ttcttcctac aacattgaca cgtccgtcgt ttttcatatc cttcaaggcg atttgtgttt
    15301 ctcctttgta ttgaccgtac ccttcattgt caatcagtac atccccatga tgcatatctc
    15361 gcgtattatg aggcgggaaa tctttatctt tgtagtatac acgagtcatc gttgaacgaa
    15421 ggatatattc tgagcgatcc cctcgataac tatgaaggtt atcaaacaag cagattcgtt
    15481 cgttttctgt aataccttct tccgtatcta ctttcaatgt tggataatcc gcgttaaatg
    15541 cttctgccat ttctttcaat tcttcttcac ttgcgtacgc atttccaata gaaatatcat
    15601 caatcaatcc tgtaaggatt aaatgcttca cttgtgtcgc aatttcaaga tctcggtggt
    15661 cttccagcgt gcacaagcca tcttgcgtag gccaagggcc aaactcagca gattgcgaat
    15721 tgacgaatgc catcgtattc aaattatatt ttctgaattt ttctgaacaa aaaacaaagt
    15781 gttcgtatcc taaaccagag tatcgatgag gataaaaatt atgagaacct aataaattat
    15841 ccgtgtttgg cgaataactc atgatgttgt caacgtaatt cgtgcccgaa ctcatattga
    15901 tctcgatttt gataccaaaa ggattgcgcg tcatttttgc ttcttctgct cctgtgaatc
    15961 cgatatctaa gcggaccccg taggcaccca tcttatggaa aaaagataag tcatcgtaag
    16021 aaatctccaa ctgttcaaat aacgctggat tgatatcaac cattacttcc atgcctaggc
    16081 tattcgcgta atcaactact tctttaaatt ctgaaagaac tttttcttta tcatcattga
    16141 tctgcagcaa actggtaaaa acccgtttat acccatactt atgagctaaa tccaagtacg
    16201 ctttgtcctt ttcaaatgtt gaccgttctg gataaatcga gattcctaat tttcccatat
    16261 taccatttcc tcctgcatct tttcgttttt gtatccactt acattatagc aaacacaaag
    16321 taaatggtct acaccttttc tttttctttt aaaataaatg ataaattcca ataatttaag
    16381 taggtatttt ccctctattt tgttatcatt aaagataaca aaatagtaaa ttggaaagga
    16441 acagttatga agaaaaataa agttatttta agtattagtt tagcagcagc attgctgttt
    16501 gctgctggtt gttctgcaaa caacacgact tcttctagtt cgtctacaga aagttcaaaa
    16561 agtacatcta ctgcggaaag cacgactgcc agtagcgtcg atttgaacgc attggaatta
    16621 ccacaattga cgaaagatgt cgccgaaaat gaagatctgg tcgaaatggt gacgaataaa
    16681 ggcacaatca aaatcaaatt atttcccgaa cacgcaccaa aagcggttga aaactttatg
    16741 acacatgcaa aagacggtta ctacaacgga ctgactttcc atcgcgtcat caaagatttc
    16801 atgatccaag gtggcgatcc taaaggcgat ggcactggag gggaaagcat ttggggagaa
    16861 ggatttgaaa cagagatcaa caaccacctt tataatataa gaggtgcgtt atctatggct
    16921 cgctcacaag atcctaacag taacggcagc cagttcttta tcgttcaaaa tacagatgat
    16981 atgcatgatg gtcttttaaa agacgactat cctcaagcaa tcatcgacgc ttataaaaac
    17041 ggcggttatc cttcactaga tggccattat actgtcttcg gccaagtgat tgaaggaatg
    17101 gatgtcgtgg atgctattgc aaatatcgaa acagatagtt cagacaaacc aaaagaagaa
    17161 gtaaaaatcg ataaaatcaa tatactgcaa gaagcaaaac aaaaataaaa aaataacgtc
    17221 tgaatcctgc atagatgaca acgtatgcta ggattcaggc gtcttctttt tacataaaaa
    17281 gcaagtaagc ttccttttgt tttgctatat caggttttat agtcaagcat tttggttgac
    17341 gatgaacgtg aactcgcact cacagacttt tttatcatct acatatgctg cagataacgc
    17401 tgtaccgact gatcccttca ttttggtgat ttcaaaatga catttcagca catctcctgg
    17461 aacaactttt tgacggaatt tggccttatt gatcccaccg atataagctc tttttcctag
    17521 aaactcttct gattttagga taagtatcga acctgcttgt gccagtgttt ctagaatcaa
    17581 cgcacccggc atcactggat tgtcaggaaa gtgaccttgg aaaaaatctt cattgattgt
    17641 tacatttttt gtcgcaacga tcttttttcc tggttctaaa gtatctacat aatcaatata
    17701 acaaatagga taacgattag gaatcaattc cattacttca gtagcagata atacgtaaga
    17761 cataattaaa ctccttcttt caggcaattg ccattttcat tactttgact atcaaagta
//
LOCUS       DADVXM010000050        17818 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.053, whole genome shotgun sequence.
ACCESSION   DADVXM010000050 DADVXM010000000
VERSION     DADVXM010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.053"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..221)
                     /locus_tag="KB927_001807"
     CDS             complement(<1..221)
                     /locus_tag="KB927_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6840724.1"
                     /translation="MKPNPVETGKRIKSIRSNFGMTMEQFADLIGNAQKGNINNWERG
                     FSLPNKERLIKIAELSNKTIDWIKWGTLE"
     gene            527..715
                     /locus_tag="KB927_001808"
     CDS             527..715
                     /locus_tag="KB927_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HBB6840725.1"
                     /translation="MPLTGKKMLKLAKKNGWKVVRITGSHHIVAKEGFPPVPIPVHSN
                     QDLKKGTEQKLLKDLGLK"
     gene            761..1138
                     /locus_tag="KB927_001809"
     CDS             761..1138
                     /locus_tag="KB927_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBB6840726.1"
                     /translation="MKKSYPVIFSAEENGYSVVFPDFAGATQGDNFEEAMSNAKEFLD
                     GILAYYIDEDISVPSPTDIHQLNNLGNNKIVSLIQSDPSPFIQKKTVRKNVTVPEWLV
                     ARGEKDKINFSKVLTDALLKIYE"
     gene            complement(1698..2870)
                     /locus_tag="KB927_001810"
     CDS             complement(1698..2870)
                     /locus_tag="KB927_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840727.1"
                     /translation="MTKKIEVYVDGSQEERDSFFGFFWKNSREYVKALNMVYKQLMFE
                     ELIENSIKELDHEYIKRELSLEERIDNLLSNEVIDQKKLDKTKRELSKLRIAKNKEAR
                     DVLTQAIGLKSQTRIRDIAKKLDFDYSDFIDSAKMKASKDFSNDFVGIVTGQRTPRIY
                     RNKNKYGLLPFRGRDIKIHKADKFYISLPKGFRFKVNLGRKPRKARDSALTLERIMDG
                     QYKLNQSNLIFEGKNLFLNLTISFEKDYHKLDFKEGAELTIKFTDLCSGKCLVNNQSV
                     IDFGDSKYISNFKNKIKAMKSREQSRGVFSKGGHGRKRKLDQDRWEAIKKRESNFVKT
                     YNNQCSAKIIQTAIRNKTQIICISEPDKNYGEWAYYQLKEQIINKGKRYGIEVKSE"
     gene            complement(3114..4082)
                     /locus_tag="KB927_001811"
     CDS             complement(3114..4082)
                     /locus_tag="KB927_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6840728.1"
                     /translation="MSLENEKPYYVVVGGVNGAGKSTIYQVQNLKRKELDTDRINADE
                     ILRSFGGNWKKQADINKSMREVLREIKGHFKEGKSFHHETTFGGNPYPDKMRLLKAKK
                     LGYESFLIYIGLDSPERAIERVKIRVAKGGHGVPEDLIRKRYEFSLRNLAELEKYFDN
                     VSIYDNSDEFSYIYVKENHTVVANNTQEYAWVPKAIQEKNAETPISKQIMMDISQEEM
                     NPKETLERIYSASDDFISDRFSKEAQVDDFYRNHKNEIKERILSISFSTGVSQDELVG
                     QDKRRNSCKLAYINSVGELLVKTDSELLSMELNRDRNIQKTDFEVE"
     gene            complement(4079..4276)
                     /locus_tag="KB927_001812"
     CDS             complement(4079..4276)
                     /locus_tag="KB927_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840729.1"
                     /translation="MRAMTEAVKELKKMYPDVLNMTVDDFHEALKNAESEEERTFYLT
                     LSSFVTRVDQKKVINQKDFKI"
     gene            complement(4287..4604)
                     /locus_tag="KB927_001813"
     CDS             complement(4287..4604)
                     /locus_tag="KB927_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840730.1"
                     /translation="MKDYASRKFIHLEPMKELVINGNEYNDYKSLFVKEQPKGGIRMK
                     NLPDFRFIEVNNLGIIEDYLDKLDEAIKQSIEKNGEDHILTVVLKDLKDRLEAEAEYF
                     NKD"
     gene            complement(4641..4859)
                     /locus_tag="KB927_001814"
     CDS             complement(4641..4859)
                     /locus_tag="KB927_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840731.1"
                     /translation="MVNKKETFKVGMEVQGVVIGSGELIEGEVISLLANVAVVKAIGK
                     APVVMKKCSMMCLDGLNNPITQRFENVI"
     gene            complement(4968..5159)
                     /locus_tag="KB927_001815"
     CDS             complement(4968..5159)
                     /locus_tag="KB927_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840732.1"
                     /translation="MEQTRMFWSDRMQDHLDCIYKTREQLNKLDTVRYYFTYFSENDE
                     QRWDIFHDGNYEEFFYTES"
     gene            complement(5321..5677)
                     /locus_tag="KB927_001816"
     CDS             complement(5321..5677)
                     /locus_tag="KB927_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840733.1"
                     /translation="MNDTIAILSDSLIDLDKTSTDYMIIEEQLKNKNPEFDIQEKSLR
                     IELPKFKQKKLITILFEIIERYGLTYYQIWTDKKDGQYTKGVSIEAVREDDQVSIKAV
                     QPLMGYNEELLNCLNV"
     gene            complement(5702..6706)
                     /locus_tag="KB927_001817"
     CDS             complement(5702..6706)
                     /locus_tag="KB927_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBB6840734.1"
                     /translation="MDLKKAKKVSIVDFCKQNGIGLKQDSREYYRLEDHDSCVISDRK
                     NLFKWNSKDLGGDIFDFIKAYYDCSFKEAKQKLEDSDYEVHSFNTKVKKAPYQYQKEN
                     EVPVSVAKSYLVNERRIDTALVEDFLSKGLIKQDKKGNVLFLWKKDQEIVGCTEQGTR
                     KFFHEGKQKDVTWKKIQENSKEYSGFNVTFGQPDKMYFFESEIDLMSYITQKPEKAEN
                     ATFVSMNGLKVGNVLHGVTEHYNKFKSLPSETVLCVDNDKAGRTFIETEFKEKGIGRE
                     GIGISEVKVDVPLREGFDWNDNLTRGKEAFKRFKLEDVSKIVNFTHKLSLNTPVYEME
                     "
     gene            complement(6743..7003)
                     /locus_tag="KB927_001818"
     CDS             complement(6743..7003)
                     /locus_tag="KB927_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840735.1"
                     /translation="MIEQENRNFLETQGEYRQINNSHFVICEDVQIAFKMALKYGKSI
                     RKKIIREKKSKKIGFWELSLRDGLNFIFCTEDYYEKYKCTLS"
     gene            complement(7012..8085)
                     /locus_tag="KB927_001819"
     CDS             complement(7012..8085)
                     /locus_tag="KB927_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840736.1"
                     /translation="MSNEQNYETGGTYRLFHGSMNKFDEFSLDHKGLNGTANGFGVYL
                     TPNKEMATMYAEQGSNGNNGFVYEVNVELEKPISMNERTITDEELSKVIDKLQESNDI
                     LNDYNDVSYYGEKVVKREVIASLSENENDVDLINDIGNTIGDHEATAKAFYDVGKYTH
                     IIAEEQLRQKDVVIVVLQPDKVKIETIHDLNEERNSLESSEDMTDKFVGHKVSEVPIR
                     EVVIKDFEQELETTNYYDKQAWQERIEYLENMEEPVSRLALDSDINEFYDSHKEEIET
                     KLTNLSEKLEIDKEELLGFPVDTSSTEYKKATSIMAYNGAMREIYNEIENDTFEIPPV
                     SEEMENKILKLTNFENTTKFEME"
     gene            complement(8093..9919)
                     /locus_tag="KB927_001820"
     CDS             complement(8093..9919)
                     /locus_tag="KB927_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBB6840737.1"
                     /translation="MAYKKGNWKPKTKEQKQKELDDLIKASNSKIEQYQSNPEDMIEF
                     AKFMSKIHNYSPLNLSLIDEGFEGAIAVASYDGWKKLGFQVKAKEKGIGIYAHAPVTV
                     FIDENGEEKTLKEATNEQKEKIKNGELRSKKIKHFKKGYVFDISQTNATEADLPKIFP
                     NRVWNFNIDGELSVSQLEKGVNHLAESMNISIKDMNESGRGEMGSARGEYIQYVDGRE
                     EIVLNSRNSRTQNLTTSIHELAHKKLHNKNEHGSSYSTPIKEFQAEMTSFIVCHNYGI
                     DTSDFTIPYIANWTKNNEKIDPKNFRQIMQEVRETSIDFISTIDKKVLEEQQTAFNAL
                     KNSFVPNENKEQIQQKSDLEFHNFYDSTINDPDRTIHGSYLEAMVDYYRGKYGENSIE
                     LTHSNYDVTAKIGENYVTYYSDTKQFDVCDVYGVVFENPSENKHDRLLLDRSPENCDY
                     VEKFVVESLKACENHELKNDTLKLSEPLRSVVINEAVYNLSENANNYYNEKCWQEEIE
                     NQTNINDVKELNSCMTAEDFYESHKQEIENTITDFESVSGTNLRDTIDNESYKEVASV
                     VAYKLVATKVKYEMDEGTFKIPENSNLEKPTVKTAERSFEME"
     gene            complement(10074..10940)
                     /locus_tag="KB927_001821"
     CDS             complement(10074..10940)
                     /locus_tag="KB927_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840738.1"
                     /translation="MKKLRVIATIPMIFSFALLLSACGKEEAGAKSNEAHNISFIDSA
                     EQKDSRCWLVVETSSKNKTPIDKNEYVKAVIQTKDGKAKVFKTDMEQLTLEKVSKMSD
                     EEIIEQALNADKQKFNDKKKSDIDSYNATLDSVKTELENEEKQEFQNDQKIADFQDSI
                     PKIQADIEEIDGVQYSEPEWKMVSATIKMDNENKSPSMETVKLSYKYLDSPIWNLNSF
                     GEVSSEGELSYESTSMDLKLSIPVATTKVLDNFYSGYSNDELDQLLLTKVASKDNKVQ
                     LDSKGKNVSIVE"
     gene            complement(11115..11378)
                     /locus_tag="KB927_001822"
     CDS             complement(11115..11378)
                     /locus_tag="KB927_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840739.1"
                     /translation="MIDFRTVMDKLSNGDFRVLIELYLNVTSTVKEFLYSNPKTALVL
                     VAVLIVFAVISFIKKMIPLLIIGAVLILGLYFPEVLDQIKNIF"
     gene            complement(11380..11709)
                     /locus_tag="KB927_001823"
     CDS             complement(11380..11709)
                     /locus_tag="KB927_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840740.1"
                     /translation="MKNFDIVCSNTKNIYLRELLNSDSETIEDVKKIIVLFEKENMEL
                     ENWGLFEIPISGNYCFYNWKTEDDVAFANYFFDKNYFSPLYIDKHSNEQVASSIKEAI
                     KLERVRK"
     gene            complement(11731..13266)
                     /locus_tag="KB927_001824"
     CDS             complement(11731..13266)
                     /locus_tag="KB927_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840741.1"
                     /translation="MVGDDMTEHIFNRKSASIILKAKFETGKSKKNNHMVELQKFVDY
                     ISRQEAIRQDKLDHDYSEDELNELARIEKALEKIEQETDQPVIKDLREMDKYIDYMTR
                     KKAILENVDNEIVNGAFSNTKRYITKKDISKIKESVIEAKNNGSVMFQDVISFDNDFL
                     VREGYYNPETNELNENVLYEATKSMMGKMQEKEELVDPFWFATIHRNTEHIHIHVTAM
                     ERKNTREIMEYDGVLQARGKRKQSTLDDMIFKFGSKILDRTNEFEKISKLRKEVPLEL
                     KQSVKDSLIQLYVENNSRYDKELVKYLKELKKEIPSTTRGYNELPEETKEKIDEVTNY
                     MTKDNPKRKEYDRMTKEIDELYQTTYGKRYNPQEYYLNRKKDFNARMGNAVVGQIKLL
                     KQSEEKNLKSNELKNLLDGKKLNVKFDREKPEFKTKYAKQSYDDFQKRLEERQLAREK
                     NEVHFKKISEKFKDKKLIRKIDRVINDDLNMYRAKNDYEVAQRMIEQEKMRQAREFEI
                     GMN"
     gene            complement(13333..13800)
                     /locus_tag="KB927_001825"
     CDS             complement(13333..13800)
                     /locus_tag="KB927_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840742.1"
                     /translation="MNYPYFKVSATEDVKEKFNKCFEVNKSVFQTKSNMFRYVVSNLP
                     MLTKANQNFRDPEKEELAKNLEEAKLKISELETIIELQKQQLENFNKKEDSTHKDYSE
                     QLNSIEESVYKLLINSGLASKELEEERAEPEQESSRLGEGTMFSSPSLRFTTD"
     gene            complement(13797..14093)
                     /locus_tag="KB927_001826"
     CDS             complement(13797..14093)
                     /locus_tag="KB927_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840743.1"
                     /translation="MDVSIRGIDPQYVKEIDKKVNKIQERTGKKFSRNDYFLAIIRQD
                     SEIDLIDYKKSEFDLVVEKLLLSNEQMVESISELTSVYERLFNFLISERSDLNK"
     gene            complement(14444..14674)
                     /locus_tag="KB927_001827"
     CDS             complement(14444..14674)
                     /locus_tag="KB927_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840744.1"
                     /translation="MCNSIVTIQEKAEEELMRIEAEYKEKRKAIKRKKNAELKKYKEE
                     QALKLGMMLCKYYDCYDINEVLKKANLNQFCE"
     gene            complement(14710..15606)
                     /locus_tag="KB927_001828"
     CDS             complement(14710..15606)
                     /locus_tag="KB927_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840745.1"
                     /translation="MNKKYSIHNKKEPNKKNKAQIDKVYKKTKGVKLYLGAILGFLAI
                     GMIIVFSPYVMGKSYDFETVKMSSAQNVTSSLNMYVDDMEINREAGLFKLVLRYQDDT
                     GTKSLSNIKSDYKLNFITNKNNEDVKTKVVKLSDEYTVIYYQNLPKDFGVISVTVNPR
                     YIYPELEPSNDLKEKEIKFYAVDKDIKSNAKLEVESTSDLQKDNFKYQIKAIENSIKD
                     EKKSIEKMNLANKVVQKDIDKANQNLEFQTLDEQTDTKNEISSMQTTIENNKSSIEES
                     ENKIKQFEEKIKQLEKSASRFE"
     gene            complement(15620..16270)
                     /locus_tag="KB927_001829"
     CDS             complement(15620..16270)
                     /locus_tag="KB927_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBB6840746.1"
                     /translation="MIKRKNDNKWKYICGVLIIILVLGGLLSQLHTSNIQAKNKKLDQ
                     EVTQLEEQNSKLSKNISDLNANVEANLTNDDGSELNKQIAEVAKKFVELYPVYDIEKV
                     EEKKADLEKIATPSVADSIVPDDMITTSKKTLESKSTTQKGEAYSSDPTFKSKYKDSK
                     LYTNYVNANTINYFAEVNYKTESSSGDTENTVYMLFEVTNKDGQVLVDNYEIKYLK"
     gene            complement(16285..17421)
                     /locus_tag="KB927_001830"
     CDS             complement(16285..17421)
                     /locus_tag="KB927_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBB6840747.1"
                     /translation="MEQNKNNNVASTLARQGMKQVSKKIGLALKIKIGVVIGLITLVG
                     LLVIGSLATLQGTQTATNTGGAEVIGGNKPLSPEVQKWQKTVEKYAEKYGIKELVPYA
                     LAIMQCESGGKLPDLMQSSESAGLPVNTLQYEESIDQGLKHLSNVYNIAKSYGMESNY
                     DGIVQAYNYGIAYMHYLGKNKKTHTIETAEAYSKNVVAPSLGNTTGQTYSYVNEVSIK
                     YGKTYLYLNGGNFYYAELVKQYIGGGSGNPANPSEFWGKMKTEMEKYQGWPYVWGGKN
                     PTTGFDCSGLTAYLYQFSAGITIDSYTVTQYEATEAVSIKEAKAGDLIFFRGTYGAPD
                     FISHVGIYVNETTMYDSNSSGIGYHNWQDSYWQSHSPEIRRVKK"
     gene            complement(17443..>17818)
                     /locus_tag="KB927_001831"
     CDS             complement(17443..>17818)
                     /locus_tag="KB927_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tra protein"
                     /protein_id="HBB6840748.1"
                     /translation="INSNNKYACEYVLSFEREMRKMRAGVYFATQTPEEIIPKDSGSE
                     VADVIRNIFNLCTFKCFFNLDSALLEDIKKVLGNTITDTEIMLLPELEVGQAVVQTSS
                     EDTYMINFDPYPEQIERFDGGQ"
BASE COUNT         5157 a         3397 c         2120 g         7144 t
ORIGIN      
        1 tcttctaaag ttccccattt aatccagtcg atagttttgt tacttaattc agcaatttta
       61 attaatcttt ctttgttggg aagggagaat cctcgttccc aattattaat atttcctttt
      121 tgagcatttc caattaaatc tgcaaattgt tccatagtca ttccaaaatt agaacgaatt
      181 gatttaattc ttttacctgt ttcaacagga tttggtttca tacaatcacc tcttttacag
      241 aatttggttt catagtatct tattcgctct ttgagttcta agttctcttt ctccaatttt
      301 tctatataat attcttgatc ctgtttcttg ttcaaaaaat gacctccaaa tttcacattg
      361 tgttacaccc tagtgttaca cctccaaacc ttattatact gtactttacc atatgataca
      421 atagggtata ccctattgtg acacttacat tctactttta atgtaaaaac tcttgacctt
      481 tatacgcata atgcgtataa taatatttgt aaggaggtag tcgcgaatgc cacttaccgg
      541 taaaaaaatg ctcaaactag ccaagaaaaa tggttggaaa gtggtgagga taactggcag
      601 ccatcatatt gtagccaaag aaggattccc acccgttcct attcctgttc atagtaatca
      661 ggatttaaaa aaagggacag agcagaagtt actaaaggac ttagggctga aatagcccag
      721 tcctttagtt cattggatta actcgaaagg agtggtggaa atgaaaaaaa gttaccctgt
      781 aattttttct gctgaagaaa atggctactc agtagttttt cctgattttg ctggagcaac
      841 acaaggagat aattttgaag aagctatgtc caatgctaaa gaatttcttg atgggattct
      901 agcttactat attgatgaag atatttcagt tccttctcca acagatattc atcaactaaa
      961 taatttgggc aataacaaaa ttgtttctct tattcaaagt gatccttctc catttatcca
     1021 aaaaaagacc gtacgcaaaa acgtcacagt cccagaatgg ttagtagcta gaggggaaaa
     1081 agataaaata aatttttcta aagttttgac agatgcgtta ctaaaaatat acgagtaaac
     1141 gtaaatatat taataacaat ttagttgcct aatgacatag atagcggaat taaaagtaaa
     1201 atagtactca tttattgcag gttcccttag aatcaataca ataaatgagt actatttaga
     1261 ctgtttaact actagtaaga tatagcgatc atcagtttca gggttatccc ttggtgacca
     1321 tagttttgcg tatttttcaa ctcgttgcca aatcaacgat tctatttttt tatttctact
     1381 taactccaaa acggagtacc ttctttttct tcgttagctc ctatttaaga gccatgtcgt
     1441 tttatataac tctaaaacag aaactactga tcaattcaat aaagccttat ttgagaactg
     1501 tgttgtttta catggtttta aaacctgatt tcccgcaaac ggtttatccg taacatttga
     1561 gaactgtgtt gttttacatg gttctaaaac ctcaacaata ttcgtccttc cgtctggtta
     1621 cacaacttga cagagctaac ccttcagtga gtgagtgtcc cctcactatt tcgttgccaa
     1681 atcaacgatt tcttattcta ctcactttta acttctattc catatctttt ccctttattt
     1741 attatttgtt ctttcaactg ataataagcc cattccccat aatttttatc tggttcagaa
     1801 atacagatta tttgcgtctt attgcggata gctgtttgaa taatttttgc cgaacattga
     1861 ttattatagg ttttaacaaa attgctttct cttttcttta tggcttccca tctatcttga
     1921 tctaattttc tttttcgacc atgaccgcct ttagaaaaaa ctcctcggct ttgctccctt
     1981 gatttcattg ctttaatttt atttttgaag ttacttatat atttgctgtc accaaaatca
     2041 atcacagatt gattgttaac taaacattta ccgctacaca aatcagtaaa ctttatggtt
     2101 aattcagctc cttctttgaa atctagctta tgataatctt tttcaaaaga aattgttaaa
     2161 ttcaaaaata aatttttccc ctcaaagatt agattactct ggtttaactt gtattgaccg
     2221 tccataatgc gttctaaagt taaagcgcta tctctggctt ttcttggttt tctacctaaa
     2281 tttactttaa acctaaatcc tttaggtaaa gagatataaa acttgtcagc tttgtgaatc
     2341 ttaatatccc gacctctgaa cggtaacaat ccatatttat ttttatttct atagattcta
     2401 ggtgttcttt gcccagtaac aattccaaca aaatcattgc taaaatcctt actagctttc
     2461 attttagctg aatctataaa atccgaataa tcaaagtcca atttttttgc tatatcacgt
     2521 attctggttt gactttttaa acctatagct tgtgtcaaaa cgtctctggc ttctttgttt
     2581 ttcgcaattc gtagtttaga taattccctt ttcgttttat ctaatttctt ttgatcgatc
     2641 acttcattac ttagtaaatt atcaattcgc tcttcaagac ttagctctct tttaatatac
     2701 tcatgatcca attcttttat agaattttcg atcaattctt caaacatcag ctgtttatat
     2761 accatattca gcgcttttac atattctcta ctatttttcc aaaaaaaacc aaaaaacgaa
     2821 tctctttcct cttgtgatcc atcaacatat acttctattt ttttagtcat agttattatt
     2881 gtcaatttta gcacctcatt attatatatc tggtatataa taatagtaac atatttccta
     2941 gactataatc aatgatcaat tgtctacttg tagtaattat attaaaaaca aaaactaaaa
     3001 ataatatatt attccttctg actacatata gtcactttat ccaaaaaata agaagtgctt
     3061 tcgcactcct tattaaattt atttactatt aattgattca gctacaactt cttttattca
     3121 acttcaaaat cagttttttg gatatttcta tctctattta attccatact taatagctca
     3181 ctatcagttt ttactaaaag ctcacctaca ctattaatat atgccaattt acaagaattt
     3241 cttcttttat cttgacctac taattcatct tgagataccc ctgtagaaaa actaattgat
     3301 agaatccgtt ccttgatttc atttttatgg ttcctataaa aatcatcgac ttgcgcttct
     3361 tttgaaaacc gatcactaat aaaatcatca cttgctgaat atattctttc aagggtttct
     3421 tttggattca tctcttcttg agatatatcc atcataattt gtttgcttat aggagtttca
     3481 gcatttttct cttgaatagc tttgggaacc caagcatatt cttgcgtatt attggctaca
     3541 actgtatgat tttctttaac ataaatataa gaaaactcat ctgaattatc atagatactt
     3601 acattatcaa aatatttctc taactctgct aagtttctta aagaaaattc gtatcttttt
     3661 cttattaaat cttcaggtac accgtggcca cctttagcaa cacggatttt aaccctttca
     3721 atcgctcttt ctggtgaatc tagtcctata tagattaaaa acgattcata acctaatttt
     3781 ttagccttta gaagtctcat tttatcggga tatggattac caccaaaagt cgtttcatgg
     3841 tgaaaagatt ttccttcttt aaaatgacct ttgatctctc ttagaacttc acgcatactt
     3901 ttgtttatgt ctgcttgttt tttccaattt ccgccaaaac ttctcaaaat ttcatctgca
     3961 ttaattctat cagtatcaag ttcttttctt tttaaatttt gaacttgata aatagtagac
     4021 ttaccggcgc cgttaacgcc cccaacaact acataatacg gtttttcatt ttctaaactc
     4081 atattttaaa gtctttctga ttaattactt ttttttgatc tactcgtgtc acaaaactag
     4141 aaagtgtaag gtagaaagtc ctttcttcct cactttctgc attttttaag gcttcatgaa
     4201 aatcatctac agtcatattc aaaacatcag gatacatttt ctttaattct tttacagcct
     4261 ctgtcatagc tctcattccc ttcttattag tctttattaa agtactctgc ttcagcttct
     4321 agtctatctt tcaagtcttt taaaacaacc gtaagtatat gatcttcacc atttttttca
     4381 attgattgct ttatcgcttc atctaactta tctaaatagt cttctataat tcctaaattg
     4441 tttacttcga taaatcggaa gtccggtaaa tttttcatcc gaataccgcc tttaggctgt
     4501 tcctttacaa ataaagattt gtaatcatta tattcattcc cattaataac caattctttc
     4561 ataggctcta agtggataaa tttacgtgaa gcatagtctt tcataataat ctctcccagt
     4621 agaaaatctt cttttttcta ttatatcacg ttctcaaagc gttgagttat tggattgttt
     4681 aaaccatcaa gacacatcat gctgcatttt ttcatcacta ccggtgcttt tccgattgct
     4741 ttaactaccg ctacattagc taacaaacta attacttctc cctcgataag ctctccgctc
     4801 ccaataacaa cgccctgtac ttccatacct actttaaacg tttctttttt atttaccatt
     4861 attccgctct ccttccatga ctacttgtag tcatttggat attttttagg ggaacggttt
     4921 tccgttccct ttcatcaaat agaatccttc atcatttcaa caaataatta actttcagtg
     4981 taaaaaaatt cttcgtaatt accatcatga aaaatatccc atctttgttc gtcattctca
     5041 ctgaagtagg taaaataata tctgacagta tctaacttat ttaattgctc tctggttttg
     5101 taaatacaat ccaagtgatc ttgcattcga tctgaccaaa acattcttgt ctgctccatc
     5161 tattatctct cctttttatt aaatcaaggg tttgagtctt tgactacttg tagtctatgg
     5221 ctatatcata caggaatgac tacttgtagt caatggtttt ctttagttta attaactgtc
     5281 tattcgtagc caaataatgt aaaaaaacgc ctagtttaca ctagacgttt aaacaattca
     5341 ataattcttc gttatacccc attaagggtt gaactgcttt aatacttact tgatcgtctt
     5401 ctctaacggc ttctatgctt accccttttg tatattggcc atctttctta tccgtccaaa
     5461 tttgataata agtaagccca tatcgttcaa taatctcaaa gagaatagtt attaattttt
     5521 tttgtttaaa ttttggtaat tcaatacgca atgatttttc ttgaatatcg aactctggat
     5581 ttttattttt aagttgttct tcaataatca tatagtctgt agacgtctta tctaaatcaa
     5641 ttaatgaatc tgataagatt gctattgtat cgttcataac acatcaacta ctttcttctt
     5701 tttattccat ttcatataca ggagtattaa gagataattt atgtgtgaag ttcacgattt
     5761 ttgatacatc ttctaacttg aagcgtttaa aagcttcttt tcctcttgtt aaattatcat
     5821 tccaatcaaa tccctctcgc aaaggtacat cgacttttac ttcactgatt cctatccctt
     5881 ctcttccaat tcctttttct ttaaattcag tttcaataaa agtacgtccg gctttatcat
     5941 tatcaacaca aaggactgtt tctgaaggca atgatttaaa cttattataa tgctctgtaa
     6001 ccccatgcaa tacattacct acctttaatc cattcatgct aacaaacgta gcattttcgg
     6061 ctttttctgg cttttgtgta atgtacgaca tcaaatctat ttcactttca aaaaaataca
     6121 ttttatctgg ttgaccaaaa gttacgttaa atcctgaata ctctttagag ttttcttgta
     6181 tttttttcca tgtaacatcc ttttgtttgc cttcatgaaa aaattttcta gttccttgtt
     6241 ccgtacaccc aacgatttct tgatcttttt tccataagaa caaaacattt ccttttttat
     6301 cttgtttaat tagtccttta gataaaaaat cttccactaa agctgtatcg attcttctct
     6361 catttactaa ataagacttt gcaacagata ccggcacttc attttctttc tgatattggt
     6421 acggagcttt tttcactttt gtattgaacg aatgaacttc ataatcacta tcttcaagtt
     6481 tctgttttgc ttctttaaat gaacaatcgt agtaggcttt gataaaatca aaaatatctc
     6541 cccctaaatc ctttgagttc catttaaaaa ggtttttacg atcactgatt acacaagaat
     6601 catgatcttc taatctatag tattcccttg aatcttgctt taaacctatc ccattttgtt
     6661 tgcaaaaatc aacgatactt actttttttg cctttttcaa atccaaacaa aaaccccctt
     6721 tactagacca tcactagtaa aattacgata aggtacactt gtatttttca taataatcct
     6781 ctgtacagaa aataaagttt agcccatccc taagagataa ctcccaaaag cctatcttct
     6841 tgctcttttt ttctctaatt atcttttttc taatactttt tccgtacttc aaagccattt
     6901 taaaagcgat ttgtacatct tcacaaatta caaaatgact attattaatt tgacgatatt
     6961 caccttgcgt ttctaaaaaa tttctatttt cttgttctat cattcattta tctactccat
     7021 ttcaaatttt gttgtatttt caaaattagt caatttcaaa atcttattct ccatttcttc
     7081 agaaacaggt ggtatttcaa acgtatcatt ttcaatttca ttataaattt ctctcattgc
     7141 accgttgtaa gccatgatag acgtagcttt tttgtattcc gtagaagaag tatctactgg
     7201 aaaacctagc agttcttctt tatcgatctc taacttttcg gataaatttg tcaatttcgt
     7261 ttcaatttct tctttatgac tatcataaaa ttcattaata tcactatcta atgctaatct
     7321 ggaaactggt tcttccatgt tttctaagta ttcaatgcgc tcttgccaag cttgtttgtc
     7381 ataataatta gttgtttcta gctcttgctc aaaatctttt atcacaactt ctcgaatggg
     7441 aacttccgaa accttatgcc caacaaattt atctgtcatg tcctcactac tttctaagct
     7501 attccgttcc tcgtttaaat cgtgaatagt ttcaatcttt actttatcag gctgtaacac
     7561 tacgataact acatcctttt gtcttaactg ttcttccgca ataatatgtg tatatttccc
     7621 aacgtcataa aatgccttag cagtagcttc atgatctcca attgtatttc caatgtcgtt
     7681 aatcaaatct acgtcatttt cattctcact aagagaagca atcacttctc tttttacaac
     7741 tttttctccg taataactaa catcattgta atcatttaaa atatcattac tttcttgtaa
     7801 tttatctatt actttagaaa gctcttcatc agtaatagtg cgttcattca tagaaatcgg
     7861 cttctctaat tcaacattta cttcatatac gaaaccatta tttccgttac taccctgttc
     7921 agcgtacatt gtagccattt ctttattagg tgttaagtac acaccaaatc cattagctgt
     7981 tccgtttaaa cctttatgat ctaaactaaa ttcatcaaat ttattcatac ttccatgaaa
     8041 caggcgataa gttccgcctg tttcataatt ttgttcatta ctcataattt tttcactcca
     8101 tttcaaaaga acgttctgct gtttttacag tcggcttttc caagttagaa ttttctggta
     8161 tcttgaaagt tccttcatcc atttcatatt ttactttagt tgcaaccagt ttataagcta
     8221 ccactgaagc cacctcttta tatgactcat tgtctattgt atctcttaaa tttgttcctg
     8281 acacagattc aaaatctgta atcgtatttt cgatttcttg tttatgagat tcgtaaaaat
     8341 cttccgcagt catacaagag tttaattctt ttacatcatt aatatttgtt tggttttcaa
     8401 tttcttcttg ccagcatttt tcattatagt aattgttagc attttcagat agattataaa
     8461 ccgcttcatt tataacaact gatcttagcg gttcgcttaa ttttaacgta tcatttttta
     8521 gttcatgatt ctcgcaagct ttcaaacttt ctacaacaaa cttttcaaca taatcacaat
     8581 tttcaggtga tcgatctaat agtaaacgat catgtttatt ttcacttgga ttctcaaaaa
     8641 ctacaccata aacatcacat acatcaaatt gtttcgtatc tgaataatat gtcacatagt
     8701 tttctcctat tttagctgta acatcataat tgctatgagt aagctcaata gaattttctc
     8761 catactttcc tctataataa tccaccatcg cttctaaata actaccgtgg attgttctat
     8821 ccggatcgtt gattgtacta tcgtagaaat tatgaaattc taaatctgat ttttgttgta
     8881 tctgctcttt attctcatta ggaacaaagg aattttttag tgcattaaat gctgtttgct
     8941 gttcttccaa gactttctta tcaatcgtac ttataaagtc aatagacgtt tctctaactt
     9001 cttgcattat ctgtctaaag ttttttggat caattttttc attattttta gtccaatttg
     9061 caatataagg aatagtaaag tctgacgtat caataccgta attgtgacaa acaataaatg
     9121 aagtcatttc cgcttgaaac tctttaatcg gtgttgagta ggaagaaccg tgttcattct
     9181 tattgtgaag ctttttgtga gccaattcgt gaatactggt agtaagattt tgtgttctgc
     9241 tatttcttga atttaataca atttcttccc taccatcaac atattgaata tattcacctc
     9301 tagcgcttcc catttcacct ctaccagact cgttcatatc ttttatagat atattcatag
     9361 attcggccaa atgatttaca cctttttcta attgactaac acttaattca ccatcaatat
     9421 taaaattcca taccctgtta ggaaatattt ttggcaaatc agcttcagtt gcattagttt
     9481 gggaaatatc aaatacgtaa cccttcttaa aatgcttgat ctttttgctt cttaattctc
     9541 catttttgat tttttctttt tgctcgtttg tcgcttcttt taacgtcttt tcctcaccat
     9601 tttcatcaat aaaaaccgtt accggagcat gcgcataaat gcctatccct ttttctttcg
     9661 ctttaacttg aaatcctagt tttttccaac catcataact tgctacagca attgctcctt
     9721 caaatccctc atcgatcaac gataggttta aaggactgta attgtgtatt ttagacatga
     9781 acttggcaaa ctcgatcata tcttcagggt tagactgata ttgctcgatt ttgctgttgg
     9841 aagccttaat taaatcgtct agctcttttt gtttttgctc tttcgttttc ggcttccagt
     9901 ttcctttttt ataggccatc ttctatctcc tttctttttt aggtaagtta aattacctaa
     9961 ttaaattata ccagatatat aaaaactctt ctatctaatt tcactgactt aatgcaaata
    10021 aaaaagagat aagatagtta tagtaaccat cttatccctt cttattttac catctactca
    10081 actatactta cgtttttacc tttactatct aattgaactt tgttatcttt agaagctact
    10141 ttagtaagca aaagttgatc caattcatca ttagaatatc ctgaataaaa attatctaaa
    10201 actttcgttg tggcaactgg aattgataac ttcaaatcca tactagtaga ttcataagat
    10261 aattctcctt cagacgaaac ttcaccaaaa ctatttaaat tccaaattgg actatctaaa
    10321 tatttataag ataatttaac ggtttccatt gaaggtgatt tgttttcatt atccatttta
    10381 attgttgctg ataccatttt ccactccggc tctgaatatt gaacaccatc gatctcttct
    10441 atatccgcct gtattttagg tatactatct tgaaaatcag caattttttg gtcattttga
    10501 aactcttgtt tttcctcatt ttctaattct gtttttacag aatctaaagt ggcattatag
    10561 ctatcaatat cgcttttttt cttatcatta aacttttgtt tatcagcgtt caatgcttgt
    10621 tctattattt cttcatcact cattttagaa actttttcca atgtaagctg ttccatatcc
    10681 gttttaaata cttttgcttt gccatcttta gtttggatca ccgcttttac atattcattt
    10741 ttatcaatag gcgttttatt tttactactt gtttcgacta ccaaccaaca acgtgagtct
    10801 ttttgttctg cactatctat gaatgagata ttatgtgctt catttgactt agcaccagct
    10861 tcttctttgc cacatgcaga taataatagc gcaaaactaa aaatcatagg tattgttgca
    10921 ataactctta actttttcat ttataagcac ctctttttta tcggtctgat atataatttt
    10981 atattatcat atttttattc caatacacag atactcttat ataatgtctt ttcatgtagt
    11041 ttatcaaatt tctatttcaa accgcttaat acaaatatca aagcccaaaa ttttctactg
    11101 gaagctttta gagcctaaaa tatatttttt atttgatcca aaacttcagg gaaatacaaa
    11161 cctaatatca acacagcacc tataattaat agcggaatca ttttcttaat aaaagagatc
    11221 acagcaaaaa ctatcagtac tgcaactaat actaaagctg ttttgggatt agaatataaa
    11281 aactctttga ctgtagacgt tacatttaag tatagttcaa tcaatacgcg aaaatctcca
    11341 ttacttagtt tatccataac cgttctaaaa tcgatcatat catttcctca ctctttccaa
    11401 ttttattgct tcttttattg aagaagcaac ttgttcatta ctatgcttat ctatatataa
    11461 tggggaaaag taatttttat caaaaaagta atttgcaaaa gctacatcgt cttctgtctt
    11521 ccaattataa aaacagtaat tcccactaat cggtatttca aaaagccccc aattctctag
    11581 ctccatgttt tctttttcaa acaacactat gatttttttt acatcttcta tagtttccga
    11641 atcactgtta agtagctcac gtaaatatat attttttgta ttactgcaca ctatatcgaa
    11701 gtttttcata atttctattc tccgtttcta ctaattcatt cctatttcaa attcacgtgc
    11761 ttgtctcatt ttctcttgct ctatcattcg ttgcgctact tcataatcat ttttcgcacg
    11821 atacatattt aaatcatcat tgattactct atcaattttt ctaataagct ttttatcttt
    11881 aaatttttca gaaatcttct tgaagtggac ttcatttttt tcacgtgcta attgtcgttc
    11941 ttctaatctt ttttggaaat catcataact ttgtttagca tatttcgttt taaattctgg
    12001 tttttctcta tcaaacttaa cgtttaattt ttttccgtct aatagatttt taagttcatt
    12061 acttttcaaa tttttttctt cagattgctt taaaagtttg atttgtccta ctacagcatt
    12121 acccattcga gcattaaaat ctttttttct atttaaataa tattcttgtg gattgtagcg
    12181 tttaccgtag gttgtttgat atagctcatc aatttcttta gtcatacgat catattcttt
    12241 tctttttgga ttatcctttg tcatataatt tgtgacttca tcaatctttt cttttgtttc
    12301 ttcaggaagc tcattgtagc cacgtgttgt actaggtatt tcttttttta attcctttag
    12361 gtactttact aattctttgt catatcttga attattttct acatataatt gaatcaaaga
    12421 atcttttaca gactgtttaa gttctaaagg aacttctttt ctcaacttag aaattttttc
    12481 aaactcgttc gttctatcta atattttgct accgaattta aaaatcatat cgtctaacgt
    12541 agactgtttt ctcttacccc tagcttgtaa aacaccatca tattccatta tttcacgagt
    12601 atttttacgc tccatagctg ttacatgaat atggatatgt tcagtatttc tgtgaatcgt
    12661 tgcaaaccaa aaaggatcaa ctagttcttc cttttcttgc atttttccca tcatagactt
    12721 tgttgcttca tatagaacat tttcatttaa ttcatttgtt tctggattat aatatccttc
    12781 ccttactaaa aaatcattat cgaatgaaat tacatcttgg aacatcaccg atccattatt
    12841 ttttgcttct atgaccgatt cttttatttt tgaaatgtct tttttagtga tatatctttt
    12901 tgtattgcta aatgctccgt ttactatttc attatctaca ttttctaaga tagctttttt
    12961 acgtgtcata taatcaatat atttatccat ttcacgtaaa tctttaatca ctggttgatc
    13021 tgtttcctgt tctatttttt ccaaagcttt ttctattcta gctaattcat ttagttcatc
    13081 ttctgaataa tcatgatcta gtttatcttg cctaatagcc tcttgtctgg aaatataatc
    13141 tacaaatttt tgaagttcta ccatgtgatt attctttttg ctttttccag tttcaaattt
    13201 tgctttaaga ataatgctcg cactttttct gttaaagata tgttcagtca tatcatcacc
    13261 caccattttc aaaaattttt tctacaggcg gttttgtact taatgctaag ttgcattaga
    13321 attttttagt gttcaatccg ttgtaaatct taatgacggt gaactaaaca ttgttccctc
    13381 tcccaaacga ctactttctt gttctggttc agcacgctct tcttctaatt ctttactagc
    13441 taatccacta ttaattaata gtttatagac agactcttct atactattta attgttcact
    13501 ataatcttta tgtgtactgt cttctttttt attaaagttt tcaagttgct gtttttgcaa
    13561 ttctattatc gtttcaagtt cgctaatttt taattttgct tcttctaagt ttttagctaa
    13621 ctcttctttt tctggatcac ggaaattttg attggctttt gttaacattg gtaaatttga
    13681 aacaacataa cggaacatat tggattttgt ttgaaatact gacttgttta cttcaaagca
    13741 cttattgaat ttttctttta catcttctgt tgctgatact ttgaaataag ggtagttcat
    13801 ttatttaaat cactcctttc gctaattaaa aaattgaata agcgttcata aactgaagtt
    13861 aactcgctaa tactttctac catttgttca tttgacaata aaagtttttc aactactaaa
    13921 tcaaattctg actttttata gtcaatcaaa tcgatctcgc tatcttggcg aatgattgct
    13981 aaaaaatagt cattcctact aaactttttt ccggtacgtt cttgaatttt attaactttt
    14041 ttatcaatct cttttacata ttgtggatca attcctctga ttgaaacatc catacacaca
    14101 cctctttcaa gctgttttta tctatctggt atatattatt atatcaaagt ccaaaggaaa
    14161 attaaagatt taaagacaag accaaggaat taatacaaag agcataaggg aaaactgata
    14221 gcaccttcct aaaggaaggt ggctaagttg gctgtgccaa ctggttttct ttcaaaatag
    14281 cttcatattt tttgctatca caaaaaaatc cattttcgac ctattttcgg tcataatata
    14341 gtacctactt ttggtcatag tttcgtccgt agttttggtc atagtaacta aagcttttac
    14401 gcccaaaaaa agagtggcaa gttttacctt gccactctct tttctattca caaaattggt
    14461 ttaaattcgc tttttttagc acttcgttta tatcatagca atcataatat ttacacaaca
    14521 tcattcctaa ttttaacgct tgttcctctt tatatttttt aagctctgca ttttttttgc
    14581 gcttaatcgc ttttctcttt tctttatatt ccgcttcaat tctcattaat tcttcttcag
    14641 ctttctcttg aatagtgaca atagaattac acattctctc taaactccct taaaataatt
    14701 taaacacgat cactcaaatc ggcttgcaga cttttctagt tgctttattt tttcctcaaa
    14761 ttgtttgatt ttattttcac tttcctctat tgaagattta ttattttcaa tagtcgtctg
    14821 catagaactg atttcatttt ttgtatctgt ttgttcgtct agggtttgaa attctaagtt
    14881 ttgattagct ttatcaatat ctttttgcac tactttattt gctaaattca ttttttcaat
    14941 tgattttttc tcatctttta tagaattttc tatagcttta atctgatatt taaaattatc
    15001 tttttgcaaa tcagaagtac tttcaacttc caatttagca tttgatttaa tatctttgtc
    15061 tactgcatag aattttattt ccttttcttt taagtcattt gaaggttcta attcaggata
    15121 aatatatcta gggttaactg tcacagaaat tacaccaaaa tctttaggca gattttgata
    15181 ataaattacc gtgtattcat ctgacaattt tacaactttt gtcttaacat cttcattatt
    15241 tttgttcgtt ataaaattta atttatagtc acttttaata ttacttagtg atttagtacc
    15301 tgtatcatct tgataccgca atactaattt aaacagtccg gcttccctat ttatttccat
    15361 atcatcaaca tacatattca aagaagacgt tacattttgg gctgaactca tttttacagt
    15421 ttcaaaatca taacttttcc ccatcacata aggagaaaaa acgattatca ttcctattgc
    15481 taaaaatcca agtatagcac ctaaatataa ttttactcct ttcgtttttt tatatacttt
    15541 gtcaatttgt gccttatttt ttttatttgg ttccttctta ttatgaatgg aatatttctt
    15601 attcatatac ttcacctcac tattttaagt acttgatttc ataattatct accaacactt
    15661 ggccgtcttt attggttact tcaaaaagca tatagactgt attttctgta tctccactag
    15721 aagattctgt tttataattt acttcagcaa aataattaat agtattggcg ttaacataat
    15781 tcgtatataa ttttgaatct ttatatttac ttttgaatgt tggatcactt gaatatgctt
    15841 ctcctttttg agtagtagat ttactttcta aagtcttttt actcgttgta atcatgtcgt
    15901 ccggcacgat agaatcagct acagaaggag tagctatttt ctctaaatca gctttctttt
    15961 cttctacttt ttcaatatca tataccggat atagctcaac aaatttctta gcaacttcag
    16021 caatttgttt atttaattca ctgccatcat cattagttaa gttcgcttct acatttgcat
    16081 ttagatcact aatattttta cttaacttgc tattttgttc ttctagttgt gtaacttctt
    16141 gatccaattt tttatttttt gcttgaatgt tacttgtatg aagttgagat aacaatccac
    16201 ctaaaactaa aataataatt aaaacaccac aaatatattt ccatttatta tcattttttc
    16261 tcttaatcat ctattttctt cctcctattt tttgactcta cgaatctctg gactatgtga
    16321 ttgccaatat gaatcttgcc aattgtgata accaattccg cttgaattac tgtcatacat
    16381 agttgtttca ttgacataaa tacctacgtg agaaatgaaa tcaggcgctc catatgttcc
    16441 tctaaagaaa atcagatcac cagcttttgc ttctttaatt gatactgctt cagttgcttc
    16501 atactgcgtt actgtataac tatctattgt aattccggcg ctaaattgat aaagataagc
    16561 tgttaatccg ctacaatcaa aacctgtcgt tggattttta ccgccccaaa cataaggcca
    16621 accttgatat ttttccattt ctgttttcat ttttccccaa aattctgaag gattagccgg
    16681 attaccacta cccccaccga tatactgttt aactaactct gcatagtaaa aattaccacc
    16741 atttaaatac aaatatgttt ttccatattt aattgatact tcatttacat atgaataagt
    16801 ctgtcctgta gtatttccta aacttggagc aacaacattt ttagagtagg cttcagccgt
    16861 ttcgatagta tgtgtttttt tgttttttcc taagtagtgc atgtaagcta ttccgtaatt
    16921 gtaagcttga actattccat catagttact ttccatgcca taacttttag caatgttata
    16981 cacattactc aaatgtttta gcccttgatc gatactttct tcatattgaa gtgtgtttac
    17041 aggcaatccg gctgattcgc tactttgcat taaatccggc aatttacctc cggattcaca
    17101 ttgcataatt gctaaagcat aaggtactaa ttctttaatt ccgtattttt cagcatattt
    17161 ttctaccgtt ttttgccatt tttgaacttc aggtgacaac ggtttgttgc caccaatgac
    17221 ttctgcacct cctgtattag ttgcagtttg tgttccttgt aatgtagcta aagaacctat
    17281 aactaaaagg ccaaccaatg ttatcagtcc tataactacc cctattttta tttttaaagc
    17341 aagacctatt ttctttgata cttgcttcat cccttgacga gcgagtgttg aagcaacatt
    17401 attatttttg ttctgctcca ttaaattcac ctccgatttc tattattgac caccatcgaa
    17461 tcgttcaatt tgctctggat atggatcaaa attaatcata taggtgtctt cactggaagt
    17521 ttgaactaca gcttgtccta cttctaattc tggtaaaagc ataatttctg tatcagtaat
    17581 tgtatttcct aaaacttttt ttatgtcttc caacaatgca gaatctaaat taaagaagca
    17641 tttaaaagta catagattaa aaatgtttct aatcacatct gctacttctg atccagaatc
    17701 tttagggata atttcttcag gcgtttgagt tgcaaaataa acacctgcac gcatttttcg
    17761 catttctcgc tcaaaactta gtacatattc acaagcatac ttgttatttg aattgata
//
LOCUS       DADVXM010000051        17753 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.054, whole genome shotgun sequence.
ACCESSION   DADVXM010000051 DADVXM010000000
VERSION     DADVXM010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17753
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.054"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            42..854
                     /locus_tag="KB927_001832"
     CDS             42..854
                     /locus_tag="KB927_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBB6840749.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            851..1651
                     /locus_tag="KB927_001833"
     CDS             851..1651
                     /locus_tag="KB927_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBB6840750.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1812..3080
                     /gene="rseP"
                     /locus_tag="KB927_001834"
     CDS             1812..3080
                     /gene="rseP"
                     /locus_tag="KB927_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBB6840751.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3148..4857
                     /locus_tag="KB927_001835"
     CDS             3148..4857
                     /locus_tag="KB927_001835"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBB6840752.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5069..9421
                     /locus_tag="KB927_001836"
     CDS             5069..9421
                     /locus_tag="KB927_001836"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBB6840753.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            9565..10038
                     /gene="rimP"
                     /locus_tag="KB927_001837"
     CDS             9565..10038
                     /gene="rimP"
                     /locus_tag="KB927_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBB6840754.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10062..11237
                     /gene="nusA"
                     /locus_tag="KB927_001838"
     CDS             10062..11237
                     /gene="nusA"
                     /locus_tag="KB927_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBB6840755.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11259..11552
                     /locus_tag="KB927_001839"
     CDS             11259..11552
                     /locus_tag="KB927_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBB6840756.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11549..11860
                     /locus_tag="KB927_001840"
     CDS             11549..11860
                     /locus_tag="KB927_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBB6840757.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11873..14179
                     /gene="infB"
                     /locus_tag="KB927_001841"
     CDS             11873..14179
                     /gene="infB"
                     /locus_tag="KB927_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBB6840758.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14206..14553
                     /gene="rbfA"
                     /locus_tag="KB927_001842"
     CDS             14206..14553
                     /gene="rbfA"
                     /locus_tag="KB927_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBB6840759.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14661..14882)
                     /locus_tag="KB927_001843"
     CDS             complement(14661..14882)
                     /locus_tag="KB927_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6840760.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            15330..17693
                     /locus_tag="KB927_001844"
     CDS             15330..17693
                     /locus_tag="KB927_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HBB6840761.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
BASE COUNT         6052 a         3149 c         3912 g         4640 t
ORIGIN      
        1 cttaagatag tgggaatctt ttaagtatag gaggaaaaag aatgttacgt ttttttccgc
       61 aaaaaaacaa atatattcaa gaaaaaagcg aatttcaatt taataccgat ggaccaattc
      121 ctcagcacat tgccatcatc atggacggca atggtcgttg ggcgcaaaac cgtcgtttgc
      181 cacgagttgc tggccataaa gaaggcatgg aaacagtaaa gaaagtcaca aaaaaagcat
      241 caaggcttgg agtgaaagtg ttgacgcttt atgccttttc gactgaaaac tggaagcgac
      301 caaaagatga agtaagtttt ctcatgcaac tacctgtcga cttctttgat acgttcgtac
      361 cagaattgat taaagaaaat gtcaaagttc atgtcatggg ttatgaaaac gtattgccag
      421 aacatacgca agatgctgta agacgtgcaa ttgagcaaac aaaaaacaat actggaatgg
      481 tattgaattt tgctttgaat tatggaagta gagcagagat cgtgactgct gtccaagaaa
      541 ttgccgaaga agtagcaaaa ggagaaatac acgcagaaga aatcgatgat gaattgattg
      601 ctaagcattt aatgacaggt ttcttgccta aagagttaca agatcctgag ctgatgatcc
      661 gtacaagtgg agaagagcga attagtaatt ttctgttatg gcagatcgca tatagtgagc
      721 tgtattttac aaaagcgctt tggcctgatt ttgatggtgc gcatcttgaa gaagcaatcg
      781 cctcttatca aaatcgagac cgtcgattcg gcggtgtaaa aaaaacagaa gatgagaaag
      841 gggatcagtc atgaaacaac gtgtgatcac agcagctgtg gcgctagtct tgtttattcc
      901 gattatatgg atcggaggca tagcggttga gcttacagca gcaatcttag cggtagtagg
      961 agtttacgag ctgttccgga tgaaaggatt gacactctta agttttgaag gagttttatc
     1021 cgccgttggt gcagtgttac ttgttttgcc aaaagaaaga tggtttttct ttcttccaga
     1081 gaatgtaagt acatttatgt tattttatct tatagttatg attcttttag gaacatcagt
     1141 tatttctaaa aatacgtata cgattgatga agcaggtttt cctgtgcttg tcagcttgta
     1201 tgtgggaata ggtttccaga attttgtcaa tgcacgaaca gaaagcttgg ctgttttgat
     1261 atttggtcta tttattgttt gggcaactga tatcggagca tatatggttg gtcgacgtta
     1321 tggtcagcat aagttaagtc ctgatatttc gcccaacaaa acgattgaag gtgcgctcgg
     1381 tggtatcggt agtgctgttg tagtcgcatt tctttattta ttgctatacc cagcaaaaga
     1441 actattcaat catggtatgt ttgtcatgct tctgatgacg attatttttt cagcagtcgg
     1501 acaatttggt gatttggtcg aatctgcaat caaacgtcat tatgatgtga aagactcggg
     1561 aaatatctta ccaggccatg gtggaatctt agaccgtttc gacagtttgc tgtttgtatt
     1621 tcctatcatg catttatttg gcattattta gtaagtatac ctgcgtttct ttgtgaattt
     1681 cataaaagac gcaggttttt atttttcatt atattgatac tattggtgtc tttggtatac
     1741 tatggtaaaa ttatagtgtt ttatcgttgt tttataaaaa acacaaaaaa caagtaaagg
     1801 agaaaaaagc tatgaaaacg attctgacat ttatcatcgt ttttggtata ttagtgattg
     1861 ttcatgagtt tggtcatttc ttctttgcga aacgatcagg aatcctcgtc cgcgaatttg
     1921 ctatcggtat gggtccgaaa atttatgggc atcaagcaaa agacgggaca acatatacgc
     1981 ttcgcctatt acctattggc ggttatgttc gaatggcagg caatggggat gatgaaacag
     2041 aaatggcacc aggaatgcct ctttctcttt tactaaattc tgacggcatc gtagagaaga
     2101 taaatttaag taagaaaatc caattgacaa atgctatccc gatggaattg agccgttatg
     2161 atttagaaga tgagctgact atcactggtt atgtgaatgg agacgaaaca gaagtagtaa
     2221 cctaccctgt tgatcacgat gcgacgatta ttgaaaacga cggaacagaa atcagaattg
     2281 cgccaaaaga cgtacagttc caatcggcta aattgtggca gcgtatgctg accaactttg
     2341 ctggacccat gaataacttt attttggcaa tcgtgttatt catcattctg gcatttatgc
     2401 aaggtggtgt tcaagtgacg aacactaatc gcgtaggaga gatcatgcct aatggagctg
     2461 cggcagaagc aggcttaaaa gaaaatgatg aggtagtcag tgtggacgga aaagaaatcc
     2521 attcatggaa tgatctgaca acagtcatta cgaaaaatcc aggtaaaaca ttagacttta
     2581 agatcgaacg agaaggtcag gtgcaatctg tcgacgtgac accgaaatct gtagagtcaa
     2641 atggcgaaaa agttggccaa cttggtataa aagccccaat gaatacaggt tttatggata
     2701 agatcattgg agggacgcgt caagctttca gcggttcatt ggaaattttc aaagccttag
     2761 gatcactatt tacaggtttc agtttagata aattaggcgg acctgtcatg atgtaccaat
     2821 tgtcttcaga agcagcaaat caaggtgtaa caactgttat tagtttgatg gcgcttcttt
     2881 caatgaatct cggaatcgtc aatctgcttc cgattcctgc cttagatggc gggaaattag
     2941 tcttgaatat ttttgaaggg attcgcggga aaccattaag tcaagaaaaa gaaggaatat
     3001 tgacattagc tggctttgga tttttaatgt tgttgatggt gctagttaca tggaacgata
     3061 ttcaacgatt ctttttctag aaaaagttga caaatagggt ataataacaa acgataacta
     3121 ttttgaggaa ataaaggagt atatagaatg agacaatcaa aaatgttgat tccaacatta
     3181 cgcgaagttc caaatgatgc agaagtatta agccatcaaa tcttgctaag agctggatat
     3241 atccgccaag tatcagcggg tatttattca tatctgccat tagcaaatcg tgtattggaa
     3301 aaactgaaac gcattatgcg ggaagaattt gaaaaaatcg gagcggtaga aatgctgatg
     3361 cctgccatct tgccagcaga actttgggaa gaatccgggc gttacgaaac atatggacca
     3421 aacttgtatc gtttcaaaga ccgcaatgat cgaaaaatga tccttggacc aactcacgaa
     3481 gaaactttta ctgatttgat gcgtaatgaa atcaattcat ataagaaatt acctttaaat
     3541 ctttatcaaa tccaacctaa atatcgtgac gaaaaacgac ctcgcttcgg tttgcttcgc
     3601 ggaagagagt ttatcatgaa agatgcatat tctttccatg caacggaaga aagtttggac
     3661 gagacatata aagattacga aaaagcctat accgaagtat tcaagcgttg tggcttagaa
     3721 tttcgctcga tcatcggaga cggcggcgca atgggcggga aagactcaaa ggaattcatg
     3781 gcgatctcag aaatcgggga ggatacgatc tgttattcga ctgaaagtga ttatgctgca
     3841 aacttggaga tggctacaag ctactatgta tcaaaaaaat cgcatgaaac acagcttgaa
     3901 ttggagaaag tagctacacc taacgtaaaa tcaattgacg aagtagcaga tttcttttct
     3961 gttgaacctc aaaaaatcat caagtctgta ttgttcattg cggatgaaca acctgtcctt
     4021 gttttggtac gtggagacca tgaagtcaat gacgtaaaac tgaaaaactt tttatctgct
     4081 gactttttag aagaagcaac agaagaagaa gcacaaaaat atctaggtgc tgagtttggt
     4141 tctgtcggac cagtcggtgt ttcagatgac gtaaaagtat atgcagaccg ttatgtccaa
     4201 gatttagcga atgccattac tggagcgaac gaaacaggat tccactataa aaatgtgaat
     4261 ccaaaacgcg atttcactgt gctttcttat gaagatcttc gttttgtaca agaaggagat
     4321 ccttcaccag acaacaacgg tgttcttgcc tttactcgag gaatcgaaat cggacatata
     4381 ttcaaaatcg gcactcgtta cagtgaatct atgggagcaa ctgtactaga cgaaaatgga
     4441 cgagaaaaat ttgtgattat gggctgttat ggtatcggtg taagtcgttt attatcagca
     4501 atcgtagaac aacattcaga tgaacaagga atcaattggc caaaaggaat tgcgccattt
     4561 gatctgcata tcgtccaaat gaatctaaaa gacgaatacc aaacaagcct gacgaatgaa
     4621 ctagaagaag cgatgacaaa agctggctat gaagtactgg ttgatgacag aaatgaacgc
     4681 gcaggagtga aattcgcgga ttctgatttg attggctgtc caatcagaat cactgtcggt
     4741 aaaaaagcag tggatggaat cgtagaagtg aaaatcaaga aaactggcga aatggttgaa
     4801 gtacgtaaag aagaattggc gaatacttta ccaatcctct tgaaccaagg cgaataataa
     4861 gcgttaaaac acagaaaata aaaatagctg aatcagctgt ttttgacaat ctgatgattc
     4921 gcttttaaaa ttggaactgc gatttgaatc gcagttccaa ttttttaatg taaaactcag
     4981 aaaaaacgag tatactaaaa ggtactgaaa aagaagagga taagatgcga tcaattgcat
     5041 tgtttctcat cagaaagggc gtatatcttt gtcagaaaaa cgagatttat ttgaaaaact
     5101 gttggaacaa atccaactag aggaagcaga aaaaaatcat ccactgctta ctgctggtga
     5161 aatggatagt gtagtggtcc atcgtaaatc gcgtttatgg gaatttacgc tacatttttc
     5221 caaaattttg cctattatgc tatatcggtc attgactcag catctgacta tcgcttttaa
     5281 agatattgca caagtcaaac tgaatatctt agcagatgac cagacattcg atgaacagct
     5341 cttgcaagat tactgggccc aagctttgga aaatcagcaa tgcgatacac cactagcaca
     5401 gcaagtattg aaaacgcagg tacctgtgat aaaagatcgt aaagtcatct tgccaatcga
     5461 cagtacagga gctatttctt atttgaagca acaatacttg ccattagtag aagagttgtt
     5521 cgtcagttac ggattcccaa aatttcgtat cgaaccagaa gtggatgagc agcaagcgga
     5581 acgtgtattg aaactttttg aagaacgcaa acaagaacag gcagaagcct ttatgaagca
     5641 agcagctgaa agtctagttg tccacgaaca aaagaaaaag gaaagaaaag agcaatcgcc
     5701 agctcttgaa ggacccatcc agctaggacg aaatattcca gccgatgaac caacgacacc
     5761 aatgatcagt atcgttgaag aagaacgaag agtcacactt gaggggtacg tattcgacaa
     5821 agaagtcaga gaactacgtt caaaacgcaa gatcttgact ttgaaaatca cagattatac
     5881 ttcatcattt atcgtcaaaa aattctcgaa cggcgaaaaa gatgaacaag tatttgatgc
     5941 gatcagtgtc ggtagctggt taaaggtacg aggaagtatt caagaagata cgtttgtccg
     6001 tgatttggtc atgaatgcgc aagatatcat agaagtcaaa catacacctc gcaaagatta
     6061 tgctcctgaa ggggaaaaac gagtagagct tcatgttcat agcaatatga gtacgatgga
     6121 tgcaacaaac agcatctctg atcttgtggc acaagcagga aaatggggac accgagctat
     6181 cgccattaca gaccatggtg gtgcgcaagc ctttccggaa gcacatagtg ctggaaaaaa
     6241 agcaggtgtg aaaatcttat acggcgtgga agcgaatgtc gtagatgatg gtgtcccaat
     6301 tgcttataat gatgcacatg aagcattgag tgaagccaca tacgtcgtat ttgacgtgga
     6361 aacgacagga ttgtctgcag tatatgacac gatcatcgag ctagccgcag tcaaaatgta
     6421 taaaggaaat gtgatcgaaa gctttgatga atttatcgat ccaggacatc cattgtcacg
     6481 aacaacggta gatctgactg gtatcacgga tgaaatggtt cgagggtcaa agtcggaaga
     6541 agaagtattg cggatgttcc ttgaattttc aaaagataca attttggtag cccacaacgc
     6601 ggcttttgat atggggttct tgaatactag ctacgcaagg tatggtattc ctgaagcggc
     6661 caatccagtc attgatacgt tggaattagc tagatatctg tatcctcaat tcaaacgttt
     6721 cggattaggt gtgttatcta aaaagtttgg tgttagcttg gaacagcatc accgagcaat
     6781 ctatgatgct gaagcaactg gtcacttagc atggatcttt gtgaaagagg caatggacaa
     6841 tcataacatg ctttatcatg atcagctaaa tgagcatatc ggagaaggag attcttacaa
     6901 aagggctcga cctttccatg taacgatttt agcaaaaaat caggcaggac tgaaagattt
     6961 gttcaaactg atttcaatgt cgaatgtcga atacttcgaa cgcgtcccac gaataccacg
     7021 ctcccaattg aaaaagatgc gtgaaaatct attgatcggc tcagcttgtg ataagggaga
     7081 aatattcgaa gccatgatgc aaaaaggggt agaagaggca agaaaccgag caaaattcta
     7141 tgattatatt gaagttatgc caaaagcggt ctatgcgcct ttgatcgagc aagaattggt
     7201 aaaaaatgaa catgatttgg aagaaattat ccaaaatttg gtagaaatcg gaaaaagttt
     7261 ggataaaatc gttgttgcaa caggtaatgt acattatctg aacgaagaag atgccattta
     7321 ccgaaaaatt ttgatcaatt ctatgggcgg agcgaatccg ttgaatcgtc atagtttgcc
     7381 ggatgtccat ttccgaacaa ccgatgagat gctaactgca tttcactttt taggggaaga
     7441 aacagcgaaa gagatcgtag tagaaaatac gaataaaatc gcagatatct gcgaagaagt
     7501 gattccagtc aaagatgaac tttatacacc gaagattcca ggttcagaag atgaaatatc
     7561 agaattgagt tacacaaaag caaaacaaat gtacggagat ccgttacctg agatcattca
     7621 aaaacgatta gaaaaagagt tgaattctat taatggtaat ggcttctcgg ttatttatct
     7681 gatcgcccaa aaactagtgc ataaaagtaa tgaagatggc tatctagtag gttcacgtgg
     7741 ctctgttggc tctagctttg ttgcgacgat gacaggaatc actgaagtta atccattagc
     7801 ccctcattat tattgtccag agtgccaata ttccgagttt tttgaagatg gtacgtatgg
     7861 ttctggattt gacatgccag aaaaacaatg tccaaaatgt ggtgcacgct taaacaaaga
     7921 cggtcatgat attccatttg agacattttt aggattccat ggagacaaag tgcccgatat
     7981 tgatttgaac ttctcaggtg attatcaagc agaagcccat aactatacga aagtattgtt
     8041 tggcgaagac tatgtttacc gtgccggaac gattggtaca gtcgccgaca aaacagcata
     8101 tggctatgta aaaggatacg aaagggacaa taatctgcag tttcgaagtg cagaagtcga
     8161 cagattagca aaaggcgcta ctggagtcaa acggacaacc ggccagcatc caggggggat
     8221 catcgttatt cccgattata tggatgtcta tgattttacg ccgatccaat atccagcaga
     8281 cgatcaaaat tcagaatgga aaacgactca ttttgatttc cactcgattc acgataatgt
     8341 attgaaatta gatattctag ggcatgatga cccaactgtt attcggatgc ttcaagattt
     8401 atcagggatc gacccacaaa cgatccctac ggatgacccg gaagtgatgc ggatatttgc
     8461 cggtcctgaa gtacttggag taagtcagga acaaatttat tccaaaacag ggacattagg
     8521 tattccagaa ttcggcactc gttttgttcg agggatgtta gaagaaacgc atcctacaac
     8581 ttttgcagaa ctactgcaaa tttccggact atctcatggt acagacgtat ggttaggaaa
     8641 tgcggaagaa ttgattcgac gaggagatgc gacactggcg gaagtaatcg gctgtcgtga
     8701 tgatattatg gtttatttga tccatgctgg attagatagc gggatggcat ttaaaatcat
     8761 ggaaactgtt cgtaaaggac aatggaacaa gatccctgat gaattgcgag aaacctatct
     8821 atcggcgatg aaagaaaata atgtgcccga ctggtatatc gattcttgtt caaaaatcaa
     8881 atatatgttt ccgaaagccc atgctgcagc ttacgtattg atggctcttc gtgtcgctta
     8941 tttcaaggtt tatttcccta ttttgtatta ctgtgcatac ttttctgtac gtgcagacga
     9001 ctttgatcta gtctccatgt gcaaaggaaa agatgctgtg aaacaagcaa tgaaagaaat
     9061 cacggacaag ggattagatg cttccgtaaa agaaaagaat caactgacag tgctggagtt
     9121 agccaatgaa atgctggaac gaggattcaa atttggaatg attgatttgt ataaatcgga
     9181 tgccgttaac tttgttattg aaggtgatac gttgatcgca ccatttagag ctgtcccaag
     9241 tttgggaacc aacgtggcga aacaaatcgt tgaagcaaga aaagacggtc catttttatc
     9301 caaagaagat cttgccaccc gcggtaaagt ttcaaaaaca ttgatcgaat atatgaacga
     9361 caatggcgta ttgaaagatc taccagatga aaatcaatta tcgttattcg atatgctata
     9421 agcatctgtt ttcctgtctg cttgtaattt taagcagagt atggtatagt tcttataggt
     9481 aatgatacta actgtgagtg agcggatttt tcgctcactc tttttaatgg aattacgcac
     9541 ttaattttta aggaggcgaa acttttgagt agcgtcgttg aaacagtcac agaaatggtg
     9601 acaccgattt tagatgaaca aaattttgaa cttgtcgaag tcgaatttgt aaaagaagga
     9661 aaaagctggt tcttacgagt atttattgac aaagaaggcg gtatcgatat cgaagaatgc
     9721 gcctttgtca gtgagaaact gagtgaaaaa cttgatgcag cagatccaga tccgattcct
     9781 caagcttatt tcctggaggt atcctccccg ggagcagagc ggccattgaa aaaagaaagc
     9841 gactatgaaa aggcacttgg tgattatgtc catgtctcct tataccaacc agtagatggc
     9901 gaaaaacaat atgaaggatt tcttcaatca tttgatgctg aacagcttac attgaaaata
     9961 cgcataaaaa cacgagaaaa agaattgact tttgaccgaa aaaatattgc aaaagctcgc
    10021 ttagctatcc aattttaatc acggagagga atcagaaaaa aatgagtaaa gaaatgttaa
    10081 atgcgttaga cgctttagaa gctgaaaaag ggatctcaaa agaaatcgtg atcgatgctt
    10141 tagaagcagc attggtttct gcatacaaac gtcactatgg ccaagcacaa aacgtcgaag
    10201 tggaatttga tcagaaaaaa ggaaagatcc atgtctatgc ggtaaaagaa gtaacggaag
    10261 aagtgatgga ttcacagttg gaagtctcat tgaaagatgc acttttaatc aatccagcat
    10321 atgagatcgg tgatacgatc cgttttgaag taacaccaaa agattttgga cggatcgctg
    10381 cgcaaacggc taaacaagtt attttacagc gtgtacgtga agcagaaaga acgattattt
    10441 ataacgaatt cagtgcttat gaaaaagaca tcatgcaagg aatcgtcgaa cgccaggata
    10501 aacgttatat ttatgtcaat cttggtaaaa ttgaggcagt tctttctaaa caagatcaaa
    10561 tgccaaatga attttatcaa ccacatgatc gaatcaaagt ttatgtttcc cgagtagaaa
    10621 atacgtctaa aggtccgcaa gtatttgtta gccgcagcca tccagaccta ttgcgtcgct
    10681 tatttgaaca agaagtacca gaagtctatg atggaatcgt tgaaattgtc agcatcgccc
    10741 gtgaagctgg cgatcgttca aaagtggcag ttcgctcaaa tgatccaaat atcgatgcag
    10801 tcggtacatg tgtcgggcca aagggacaac gagttcaagc aatcgtcaat gaattaaaag
    10861 gcgaaaacat ggatatcgtc gaatggaatg aagatccagc tgtattcatc gcaaatgcat
    10921 tgaatcctgc acaagtcatg gatgtgatct tcgatgagac aaatccaaag gcctgcacag
    10981 ttgtcgttcc agactaccaa ttatcgctag caatcggtaa acgcggacaa aatgcacgtt
    11041 tagctgctaa attgactaac cataaaatcg atatcaaatc agaatctgac atgacggaat
    11101 tttatgaaaa tcaagaacaa caaaaagaaa cagaagaact gcatgatgaa gcaatcgttc
    11161 agtcagattt aacagacgat gaatatgaaa caattgcatt caacaatgaa acggtcgaag
    11221 aaaaaccaga agcttaactt tagtaaggag gcaaagagat gaaacaaagg aaaattcctt
    11281 tacgcaaatc cgtggtttca ggtgaaatga aacctaaaaa agagatggtc cgaatcaccc
    11341 gttcaaaaga aggggaagta tcgatcgatc caactggaaa aatgcctgga cgaggagcgt
    11401 atgtctcact tgagccggaa gaagtacaac aagcttggga taaaaaaatt ctcgatcgag
    11461 tactcgaaac aacattaaca gatgagtttt atcaagaact tcttgactat gtcactcacc
    11521 aaaaagcacg taaagagtta tttggaaaat gaatacagtt aatcggcaaa aagccatgaa
    11581 tctcatcggt ctagcgatgc gcgcgggaaa actaatcacg ggtgaagaac tgaccattgc
    11641 tgaaatccgc aaacaaaaag caaaattggt gtttgtggca accgatgcaa gtgagaatac
    11701 aagaaaaaag ataaaagata agagttcata ttatgaagtt ccttgctttg agctattttc
    11761 tgaagcagaa atcacgcaga tgatcggaaa acctcgcaag gtattcggaa taatggatgc
    11821 cggatttgcg aagaagacca aggagctaat tgaaggttag gaaggtgatt gcatgggcaa
    11881 caaaagaatc tatgaattag caaaagaact caaaaaatct agtaaagacg tcgtggaaaa
    11941 agcacaacaa cttggcatcg atgtgaaaaa ccatatgggt gcgattacta gcagtgatga
    12001 gaagaaattg caacaagcgt tcaaaaaccc aagcacgaaa caacaagctg cacaacaagc
    12061 aagcagaaaa ccagccaatc aacagccgaa cgatcaacgt aaaaaagaaa caacgaacaa
    12121 tcaacaaaaa aataaaaata accgcagtta tcaagatcgc ggtcaaggga gcggtcaagt
    12181 gaatcaagga aaaaaaccaa caacaaacca aaataatacg ggaaatacca gcagccaaaa
    12241 tcgtcaagga acgagccaag gcggcaatca aaaccgtact aacaataaca acaaaccaaa
    12301 caataacaat cgcggcaaat ttaataataa taaccgtaat cgttataata aaaaaggtaa
    12361 aaaaggcaaa cagcaacaat caactaaacc agctgtacca ccacgcaaat tccgtgaatt
    12421 gccagatgta ttagagtata ctgaaggtat gaacgtagca gatattgcga aaaaaattca
    12481 tcgtgagcca gcagaaatca ttaaaaaatt atttatgctt ggtgtcatgg tcaatcaaaa
    12541 ccaagcactg gataaagata cgattgaact gttagcgacg gactatggca tggaaccaca
    12601 agaaaaagtc caagttgaca ttgctgatat cgataaattc ttcgaggcag aagaagtcga
    12661 tccagataaa ttagtctcac gtccgccagt agtaacgatt atgggacacg tagaccacgg
    12721 gaaaacaacc ttattggata cattgcgcca ttcacgtgta acaagcggcg aagccggcgg
    12781 aatcacacag catatcggtg cctaccagat cgatattgat ggtaaaccaa tcactttctt
    12841 ggatacacca ggacatgcgg cctttacaag tatgcgtgca cgtggagcaa gtatcacaga
    12901 tatcacgatc ttagttgttg ctgcagatga tggcgtcatg ccacaaacag ttgaagcaat
    12961 caaccatgcc aaagctgcag gcgttccaat catcgtcgct gtaaataaaa ttgataaacc
    13021 aggtgcaaat cctcagcatg ttatgcaaga attaagtgag tatgaattaa ttcctgaagc
    13081 atggggtgga gaaacgattt ttgttgagat ctcagcgaaa ttcggccaaa acatcgaaga
    13141 attgctggaa atgatcctgt tagtcgcaga agtagaagat ttaaaagcag atccaacaca
    13201 acgcgcaatc ggaacagtga tcgaagcacg tcttgataaa ggtaaaggtc ctgtgtcaac
    13261 cttacttgtc caagaaggaa cacttcacgt tggtgaccca atcgttgtcg gtaatactta
    13321 cggacgtgtc cgtgtaatga caaacgatct tggccgtcgc gataaagaag caggacctgc
    13381 aacgccagta gaaatcactg gcttgaatga tgtacctcaa gcaggtgacc gtttcgtagt
    13441 cttcgaagac gaaaagacag cacgtgcagc gggtgaagaa cgcgcaaaac gtgcattatt
    13501 ggaaaaccgt gctgccacaa gccgtgtgac tttggacaac ttatttgaaa gcctgaaaga
    13561 aggcgaattg aaagaagtta acgtaatcat caaagcagat gtacaaggtt cagcagaagc
    13621 actggctgca tcattgaaga agattgatgt ggaaggtgtc cgtgtaaaaa tcgtccattc
    13681 agctgtcgga gcaatcaatg aaagtgatgt aaccttagca gcagccagca acgctattat
    13741 catcggtttc aacgttcgtc ctacaccgca ggcaaaagtg caagctgata ctgaagaagt
    13801 cgatattcgt cttcaccgta tcatctataa agccatcgaa gaaatcgaaa ctgcgatgaa
    13861 agggatgcta gaccctgaat ttgaagaaaa aatcaccggt caaatgatcg ttcgtgaaac
    13921 cttcaaagtt tctaaagttg gtacgattgc aggtgcctat gtaacagaag gatatattcg
    13981 tagagatagc ggtgtccgtg taatccgtga cggaatcgta atctatgaag gccaacttgc
    14041 aagtctgaaa cgattcaaag atgacgtgaa agaagtcaaa atgggttatg aatgtggtgc
    14101 gatgattgaa aaattcaatg acatcaaagt agatgacgta attgaaggat ttatcatgga
    14161 agaagtcaaa aatgactaaa aactgataaa aggaggccaa tcattatggc taactaccgt
    14221 gatcgccgag tcggtcaaga aatcttaaaa gaagtcaatg atattttgcg caaaaaggtc
    14281 cgtgaccctc gtgtggagaa cgtaacgatc acagatgtga aagttacggg ggacttacag
    14341 caagcaacga tctattacag cattttatct gacttagcat cagataagaa aaaagcacaa
    14401 gatggattga ataaagcatc aggattgatt cgtcgagagt tagggcacaa tctaagtatt
    14461 tataagacac ctgaattgtt ctttgaactt gatgaatcag ttgtctatgg gaaccatatc
    14521 gatgaattgc ttcgcgactt gaacaaagac taatcaaaaa atcccgcaaa tcctgtgaaa
    14581 tcaggggttg cgggattttt ttgttttcat taagacgtat tacctaagag ttccatgact
    14641 ttagtctggt agcgtgtcag ctaaccaaaa aagagaaaaa gaaaagtaaa aaattcgact
    14701 ttcttttttc tatagtatat aaatttttgc atatagataa agatcaagat accgataacg
    14761 gaagctagat tgtaatctat tttagtgaca gtcaggtata gccaagtaac tagaagatca
    14821 gtggaacctg caccataaaa gtttgagttt gtcggtccgt tgacagttaa aagaaaaatc
    14881 acgttgaagt tattgatatt tccgattacg ccgcttcgat ttggtcacga tccaaatttt
    14941 ggataatccc tgtagaaatt agcatagtag ctgggatacc aattcacata ttgacaaaga
    15001 taacagagac ttttacataa aacggatcaa tcaggaaagg aattgctcga tccagcccca
    15061 gttttccaac aatgtgttaa ctggcctagc gtcattcagc aaattatgca tgatgaggag
    15121 cgaaatgaac tgcggaacag ccattgtgat aacgacaagt tttttggatc aatgtaaaaa
    15181 acgtcagcga aaggaaaaat ttcgtggttt tttatacctg ttcatttggc tagatataaa
    15241 atccaaacaa atgaacagaa gtgcttatta ggtttcaatt gggagtatct gcgctagaat
    15301 aagagtaata atgaaaagga gtgttatgta tggattattc tagtaaagaa tactttgata
    15361 aaatgacggc ttggtggcgt gctgctaatt atctttctgt tgggcaactt tatcttaaag
    15421 ataacccctt actgagacgt acactgaaac cagaagatgt caaaaaacat ccaatcggtc
    15481 attggggaac gattcctggc caaaatttta tttatgtcca tttgaaccga gtcatcaata
    15541 aatatgattt gaacatgttt tatatcgaag ggccaggaca cggcggacaa gtcatggtat
    15601 cgaatgctta tttagatgga agttacacag agatctatcc agaagtaacg gaagatgaga
    15661 caggaatgca aaaattattc aagcgatttt catttcctgg aggcattgct tctcatgcag
    15721 caccagaaac accaggttct atccatgaag gcggagagct tggatactct ctttcacatg
    15781 cagtcggagc tgtattagac aatcctgaag taatctctgc tgtcgtgatt ggtgatggtg
    15841 aagcagaaac cggtccttta gctggaagct ggttctcaaa tgtctttatc aatccagtga
    15901 tagatggagc tgttttaccg atccttcatt taaatggtgc aaaaatagcc aacccaacga
    15961 tcttggcacg taaatcagat ggagaattag caaattactt taacggactt ggctgggagc
    16021 ctttctttat tgaaggaaat gatccagaaa aattaaatcc tgttatggct gaaaaaatgg
    16081 atcaagcaat cgagaaaatc aaatccatcc aaaaagaagc tcgcctgaag acagcaacag
    16141 atgtcgtgat gccaaaatgg ccagtattga tcgtacgcac accaaaagga tggaccggtc
    16201 caaaagaatg ggacggggaa ccaattgaag gaaccttccg agcacaccaa gtaccgattc
    16261 ctgtagatca agaacatatg gatcatgcag atgctttact ccgttggctg aaatcctatg
    16321 aaccagaaaa attatttgat gcacaaggac gtattttaga agaaatcaga gaaattgcgc
    16381 ctactggtga ccaaagaatg gcaaaaaatc ctatcaccaa tggtggaatc gatccaagac
    16441 cgcttattat gccagattgg aaaaaatata ctttgcaatt tgaaaaacca ggctccgtta
    16501 aagcagaaga tatgaccgaa cttggtaaat tcgttcgcga gatcattgag aaaaatccag
    16561 aaaatttccg tatatttgga ccagatgaaa caaaatcaaa ccgattgaat caagttttca
    16621 aaacgacaaa tcgccaatgg atggaaaaaa tcgaaccaga aaatgatgaa tggctttcgc
    16681 catctggtcg cgtcatcgac agtcaattat cggaacacca agatgaaggg ttcttagaag
    16741 ggtacgttct gactggacgg catggttttt ttgcaagtta cgaatcattc ttgcgagtgg
    16801 ttgactctat gttgactcag cacttcaaat ggatacggaa atcacatgac ctttcttggc
    16861 gaaaagatta tccttcgctg aatctcattg caagctcaac agtcttccag caagatcaca
    16921 atggatatag ccaccaagat ccaggaatat tgacacattt ggcagaaaag aaggcggagt
    16981 tcatccgtga atatctgcct gcggatgcaa atacattgct cgcagtcatg gataaagcat
    17041 tccgctcgtc agaaaaaatc aatttgatca tctcttccaa acatccgcgt gctcaatttt
    17101 actcagcaga agaagcagcc gtcttagtga atgaaggctt gaaaatcatt gattgggctt
    17161 cgacagcaaa agaggaggaa cctgaattgg tcattgctgc tgcaggaacg gaatctaact
    17221 tagaagcatt agcagctgta actttgctgc tggaagaatt cccaaaacta aaaattcggt
    17281 tcatcaatgt cgtagattta ttgaaattac gtcatccaag tcaagatccg cgtgggttga
    17341 gcgatgaaga atttgatcaa tattttacaa aagacaaacc gatcttattt gctttccacg
    17401 gttatgaaac attggtccgc acgattttct ttgatcgtca taaccatcat ttaatgattc
    17461 atggctacaa agaaaatgga gatatcacga caccatttga catgcgtgta gtaaatgaac
    17521 ttgatcgtta tcatttggca aaagacgcag ctttaaaaat caaaggaagt caagcagaag
    17581 attttgcgga aaaaatggat cagaaattac aagaacatca aaactatatt cgtgaaaatg
    17641 gtattgatct gccagaagta ttggattgga aatggaaaaa tcttgaccaa taaaatgata
    17701 aaatcgatcc cgcaaaacag aattttttac attgtattat ttgtcaaatt aag
//
LOCUS       DADVXM010000052        17177 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.055, whole genome shotgun sequence.
ACCESSION   DADVXM010000052 DADVXM010000000
VERSION     DADVXM010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.055"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(543..2048)
                     /locus_tag="KB927_001845"
     CDS             complement(543..2048)
                     /locus_tag="KB927_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6840762.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="KB927_001846"
     CDS             complement(2045..2731)
                     /locus_tag="KB927_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6840763.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="KB927_001847"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="KB927_001847"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBB6840764.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            complement(4515..4694)
                     /gene="rpmF"
                     /locus_tag="KB927_001848"
     CDS             complement(4515..4694)
                     /gene="rpmF"
                     /locus_tag="KB927_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBB6840765.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(4752..5321)
                     /locus_tag="KB927_001849"
     CDS             complement(4752..5321)
                     /locus_tag="KB927_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBB6840766.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            5507..6409
                     /locus_tag="KB927_001850"
     CDS             5507..6409
                     /locus_tag="KB927_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6840767.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(6444..8228)
                     /gene="pyk"
                     /locus_tag="KB927_001851"
     CDS             complement(6444..8228)
                     /gene="pyk"
                     /locus_tag="KB927_001851"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBB6840768.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(8302..9264)
                     /gene="pfkA"
                     /locus_tag="KB927_001852"
     CDS             complement(8302..9264)
                     /gene="pfkA"
                     /locus_tag="KB927_001852"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBB6840769.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(9432..12746)
                     /gene="dnaE"
                     /locus_tag="KB927_001853"
     CDS             complement(9432..12746)
                     /gene="dnaE"
                     /locus_tag="KB927_001853"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBB6840770.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLIKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLIENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKDGSQIPLENLSASLPLT
                     ANGYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            12973..13158
                     /locus_tag="KB927_001854"
     CDS             12973..13158
                     /locus_tag="KB927_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBB6840771.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(13220..14416)
                     /locus_tag="KB927_001855"
     CDS             complement(13220..14416)
                     /locus_tag="KB927_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6840772.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNIFLSLFNFRK
                     VLRSRL"
     gene            complement(14586..16022)
                     /locus_tag="KB927_001856"
     CDS             complement(14586..16022)
                     /locus_tag="KB927_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBB6840773.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNEVSVALWIVDILFIINFIILATI"
     gene            16315..17124
                     /locus_tag="KB927_001857"
     CDS             16315..17124
                     /locus_tag="KB927_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6840774.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLNNQEDGLAVYLEKLLKL"
BASE COUNT         5046 a         3597 c         2976 g         5558 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat attttttatt
     4441 taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt tttacatttt
     4501 ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata gtaaccacaa
     4561 tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc gtttaaccct
     4621 ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga tgttcttcta
     4681 gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat tagacacaat
     4741 atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag ttcagatagt
     4801 tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg ctggtattct
     4861 tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc ttcctcttct
     4921 tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga ctctgctaaa
     4981 ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc atctctactt
     5041 tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg cagttcaaca
     5101 ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta atgaacgata
     5161 tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac atcaagtatt
     5221 aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa agttaacggt
     5281 gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca ctcctaagca
     5341 acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt gacaccttgc
     5401 agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat catcctcaga
     5461 atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga acacgaaaga
     5521 tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg ctaattattt
     5581 ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag agtttgacac
     5641 cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt ctggaaagca
     5701 gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag ctgaaatcac
     5761 tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca atgaatactt
     5821 tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg agattaccga
     5881 tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt tagctgtatt
     5941 aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt tggacaaacg
     6001 tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg tctctttcaa
     6061 agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc ccgcagcatt
     6121 cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa gcaatgactt
     6181 gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg cagagattgc
     6241 tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc agcctcgctt
     6301 cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag aacaagtagt
     6361 ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa agaagagctg
     6421 tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta aacgatgccg
     6481 cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc gcctttagca
     6541 ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga agtcaatccg
     6601 ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc tttgtcagtt
     6661 gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc agcagatgaa
     6721 gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc taataattta
     6781 gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac tggtacacca
     6841 gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc ttttttagct
     6901 gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg gtaaacgccc
     6961 cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa gatatctgca
     7021 tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc agcaacgatt
     7081 gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt ttcagttaca
     7141 tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc attttcagct
     7201 tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc gtttgcagat
     7261 tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac gtcagaagct
     7321 tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt agcagtgata
     7381 actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat tggtactagt
     7441 tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc agaaactttg
     7501 atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa gatttgaaca
     7561 tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg tgctttacgt
     7621 acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat atcgtcagca
     7681 tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac ccctttacgt
     7741 gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc ttcgtctttt
     7801 tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc aacgtgaaca
     7861 tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac atgttcagga
     7921 tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc acgaccaaaa
     7981 tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt atctaaaaga
     8041 ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat acgtgataat
     8101 tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc agattcaatc
     8161 aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac gattttggtt
     8221 tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta cacagcttaa
     8281 atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat atagtgataa
     8341 gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa cgatttcgtt
     8401 gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga cagcgtaagc
     8461 accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac ggacaacgtg
     8521 tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct cagcgaattc
     8581 atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc cgcgatcgcg
     8641 gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg ggatgatgat
     8701 ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat tgcgtcccat
     8761 tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac ggtcaattga
     8821 ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc caggaatatc
     8881 attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca aagccattgc
     8941 gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga attttttcaa
     9001 ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac gtgcagaata
     9061 caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa gacgacgaat
     9121 atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca gtccttcgta
     9181 aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt ctccgccact
     9241 ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac tttatcctaa
     9301 gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct aacattattt
     9361 ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca agtagtattt
     9421 tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat aagttgcccc
     9481 tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt tcgttgcgtt
     9541 ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat cacttgtaat
     9601 tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca agtttgtgaa
     9661 ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag ttgcagttcc
     9721 tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc aacggcaaac
     9781 aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc tccactactg
     9841 tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc tctaacttcc
     9901 ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat cagctgaact
     9961 tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa ataaatacct
    10021 aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac ttcttcttct
    10081 tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat attttggatt
    10141 tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc aaaaactcct
    10201 actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat ccgtatgagg
    10261 aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat atcttctaca
    10321 aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc cttattgacc
    10381 aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag tttattttta
    10441 cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga attcatcagg
    10501 ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa tcccacgaat
    10561 gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc gatatattca
    10621 tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga tacaaaatgc
    10681 gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg cagaatatct
    10741 gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg ttcctgatag
    10801 acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg gtagcgaatg
    10861 gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg gcctggtcga
    10921 tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct tcgtaaaacg
    10981 ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg ttgaaacaag
    11041 agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata cccttctact
    11101 cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc taaaaagtcc
    11161 attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag aaaagcttca
    11221 tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat aactacacct
    11281 gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt tttgaataaa
    11341 agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt tttataagct
    11401 tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt tgcttcactt
    11461 tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc cattgtgcca
    11521 aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata attcaatact
    11581 tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa gcgttcgggg
    11641 tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt gatttctaac
    11701 acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac gattttgttt
    11761 ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa tcccatttga
    11821 tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata gtcagtgatt
    11881 cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg ttttccatta
    11941 ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga aatcgattca
    12001 gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa tcgtttgatc
    12061 atttcttgtt ctgaaagaag atagccattt gctgttagtg gtaaagatgc agataaattt
    12121 tctaaaggta tttggcttcc atctttgata tgtttcatca cttcaagtgc aaaaagttct
    12181 tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc ttttatcaca
    12241 tactgatacc attcaggcaa ttgatcaggc gtgttttcta tcaagccgat ataaaaattt
    12301 ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc ctctttattg
    12361 aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc ggtttctgtc
    12421 atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt tatcagctgc
    12481 tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc ttcataagta
    12541 taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat acgatagaat
    12601 tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta gccttgtttt
    12661 tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga ataagaagta
    12721 attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt taaaattcac
    12781 tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg aagttgatta
    12841 ttccacttca tttgcttgta atctgtagga atgagttctt tcgcaagaac tcaaatttta
    12901 ttgagatttg gtctcgtttc tttacattca aagaaaatct ggtaaaatta agatagaaaa
    12961 gaggtgttct ttatgcgata tatcgttaca ttattctggg ctgtcgttct aggtcaagta
    13021 gtcggttata ttggtgctgc attaacaagc ggaacatatg attttacttt gacaacaatc
    13081 atttcattca ttgcgggtgt cattatcctt ttgattggtg cagttgcgcc aagaaaagaa
    13141 acctctgccc attcgtaaaa aaacagccaa gagcttgaga tatctcaagc tcttttttat
    13201 tttctgctcc tcaccaccat tataatctgc tgcgaagaac tttacgaaag ttgaataaag
    13261 aaagaaaaat atttgacaga acaaacaaac ttgtcacaat aaaaacagca ctgtaattat
    13321 aagcatgcgc gactgtcgat cctagcatgg gacctaaaac ttgtccaaag ttgctaaaca
    13381 tctgattgta gctatagatt cggctgactc cttcttgagg cgtaatctta ctgatcagtg
    13441 tattgacaga aggcatcaaa gcgccagttg aaaagcctaa aataaagcga agtataccta
    13501 attggagcgg tgtagtgacg aatgccatag gtaaataaca gcaaaatgat aaaatgagtc
    13561 ctccaattag aactttttga ttcccaatct tatcccctag ttttcctagt ttcggtgaag
    13621 aaaaaacagc ggaaacacca gctatcgaaa caatcaagcc gctgacaaaa aggatatttt
    13681 ctgtacttcc gctcaattca cgaatatata aggtcaaaat agggctgatc gtagtgattc
    13741 ctatctgtaa aatcaaggtc gtaatgaaga gaccgatcaa aatagagaga tgatccattt
    13801 ttgaaaaaat ttctttggtg cttatcagat cttttttctc gatcggatgg aaatcttctt
    13861 tgactaagaa aatggtcaat accgttgtga tcatcaacaa agcccctgtg atcaagaata
    13921 cattttccat accaaaccac tgagccagtg caccgcccat tgaaggtccg atcagatttc
    13981 cagcaatcgc tccggtagac aatgttccta acgcccatcc gctcttttct ctaggtgcct
    14041 gtgaagcaat catcgctgtg gcatttggaa tatatccaga caaaattcca ttccaaaacc
    14101 gcatgatcaa aagccaatac gcgttcggta caaaagccaa agatcccatt gttaatgtca
    14161 tccctgctgc tgcacggatc atcatgagtt ttcgtccttt tcgatcagct agattccccc
    14221 agattggcgc aaccacggca gatgcaaaag cagtcacaga gattgctagt cccgaaaaca
    14281 attcgatttg atcttttggt gttcctagtt gctcaacata aactggtatg aatggcataa
    14341 ctaaactaat acttgcacca gtgaaaaaac agccaatcca cgcaatcact aaattttttc
    14401 tccaattaat ctccatctat catccctctt tcgtctcttt tatcatacct attttcgaat
    14461 aaacaagcaa cgatctcgcc agtaaaaaga gaaaaatccc gcaaaggtca ttttatatgt
    14521 aacgttcttt ttatgtaaaa caaaaagaga tcagaacaaa tactgttcca atcccttctc
    14581 tttagttaaa ttgttgctag aatgatgaag ttgataatga ataaaatatc aacgatccac
    14641 aaagcaacag aaacttcatt gtattttcct ttgattactt tcacaattgt atagaaaata
    14701 aatcctgctg caatcccata ggaaatgcta tagcacaatc ccataaagat cgatgcaaag
    14761 aaggccggta aagcttcttc catatctagc catttgatgt ctgcaaaaga agccatcatc
    14821 attactccaa ctaaaatcaa tgctggcgca gttgcttgat ttggtacaat ggcgatcagt
    14881 ggagagaata aactacttaa tgcgaatagc actgccacta ctactgaagt caaaccagta
    14941 cgtccaccgg ccccgatccc agctgcagat tcgacataag ttgttgtatt cgatgtacca
    15001 aagatagccc ccacggaagt agcgatcgca tcggcaaata gtgctttatc catttttgtt
    15061 ttgaacccac gaccatcttc caacgcgatc tcgtcttctt ttgagaaaat gcctgtgcgg
    15121 cgtcctgtac cgataaatgt tccgatcgta tcgaaagtat cagataaact gaatgcgatg
    15181 atcgtcatca atacttgagg aatcttggaa gaatcactga ataaagattg catgccttca
    15241 gaaccaaatg ctgcaccgaa agttgttcct aattctttaa atgaattacc taacgaattc
    15301 gtttgccaat caatggaact taaatcaaca acacccataa aaataccaag gactgtggtc
    15361 gctacgatac cgataagaat agccccacgg acatttttta caactaaaat ggctgtcagt
    15421 accaaaccaa tcacagccaa taagatagga gcgttgtcaa agttggctaa cgcagggacg
    15481 attccaccat ttatcgtaac atttgtcgct tttccgcctt caacgacaga gctcgaaata
    15541 gctgactggt ctgctgaaaa agataagaat cctgcatttt tgattccgac atacgcaacg
    15601 aaaataccga tcccgccacc aatcgcatgt tgaagacttt cgggaatcgc ccgaataatc
    15661 atttttcgaa tatttgtgac agtaataaaa atattgatta atccgcaaat aaacaccatt
    15721 gccaaggctt gttgccaaga ataaccaagc ccaaaaacaa ccgtaaaagt gaaaaatgcg
    15781 ttcaatccca taccaggtgc ctgagcatat ggtacatttg cgaacaatcc cattaccagc
    15841 gtaccaataa tcgatgcaat gattgtcgct agaaatactg cttggaaggg catacctgat
    15901 gctgacaaaa tcgtcggatt tacgaataag atataactca tggcaaagaa tgtcgttact
    15961 cccgccatta tttcagttga tacatttgta ttgtttttct ttaaaccgaa aaacttttcc
    16021 ataaaaagtt ccactccctg aatttttttc tgatggaaaa ctataataat aaaaaataag
    16081 taaaataggg caaatccatc gaacaatttc aaattatata gacgtttcat tcgcttttca
    16141 acgttttttt aacaaaaaaa gcgaaaataa tacttaacgt tcgtgtttag cttatgttta
    16201 gctatttata tagccataac tgtagttttt gttaggaata gctgattgct cttgttaatt
    16261 acctaaaata tgctagacta aaacaaatgc tagttgagga aggaaggacc cttattgaat
    16321 aaaaaattaa ttgccatcga tctggacgga actaccctca atcaagattc gatgattaca
    16381 tctaaaacaa aagagactct gaaaaaagca atcaatgccg gtcatcatgt cagtattgct
    16441 acaggacgcc cattccgaat gagccatcag ttttaccaac aattagaatt aacaacaccg
    16501 atggttaatt ttaacggcgc attagtacac atccctaatc agcactggga tggtgaaaga
    16561 gaaacgttga tcaatcgtga aatcgctttt gaaatcttat cgcaaaaaaa gcagctaaat
    16621 ttagatttta tcgctgctga aaatcgtgat acttttttta ttgacagttt tgatttcttt
    16681 gatgaaaaaa tttttgcttc ttctcgtcca ggagagaaga atttgctttc tcctaaaaat
    16741 ttgacgacaa atcctacatc tttgcttgtc cgaacagaca aacgttttgc aggagctgta
    16801 tctgctgaat taacacgtca atttggcagt tatgtcgatg ttcggacatg gggtggacct
    16861 actgccatct tagagattgt ttcaaaagga atccaaaaag caaaaggcgt gcaagagatt
    16921 gctaactacc tgtctatcga tcaaaaagac gtcattgcct ttggtgacga gcataatgat
    16981 ttggaattgt tggattatgc aggttgggga gtagctatgg ctaacggtac tgatcaactc
    17041 aaaggcattg caaatgatgt cactcctttg aacaatcagg aagacggttt agctgtttat
    17101 ctggaaaaac tacttaaact ataatagaga attagattcc acaaaaaaga ggttgtgaca
    17161 atttttgtca caacctt
//
LOCUS       DADVXM010000053        17137 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.056, whole genome shotgun sequence.
ACCESSION   DADVXM010000053 DADVXM010000000
VERSION     DADVXM010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.056"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(92..637)
                     /locus_tag="KB927_001858"
     CDS             complement(92..637)
                     /locus_tag="KB927_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6840775.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(649..1341)
                     /locus_tag="KB927_001859"
     CDS             complement(649..1341)
                     /locus_tag="KB927_001859"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBB6840776.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1360..1644)
                     /locus_tag="KB927_001860"
     CDS             complement(1360..1644)
                     /locus_tag="KB927_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840777.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1657..2220)
                     /locus_tag="KB927_001861"
     CDS             complement(1657..2220)
                     /locus_tag="KB927_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6840778.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2448..3110
                     /locus_tag="KB927_001862"
     CDS             2448..3110
                     /locus_tag="KB927_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBB6840779.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3234..4430
                     /locus_tag="KB927_001863"
     CDS             3234..4430
                     /locus_tag="KB927_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBB6840780.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4531..5907)
                     /locus_tag="KB927_001864"
     CDS             complement(4531..5907)
                     /locus_tag="KB927_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6840781.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5944..6810)
                     /locus_tag="KB927_001865"
     CDS             complement(5944..6810)
                     /locus_tag="KB927_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBB6840782.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6899..7924)
                     /locus_tag="KB927_001866"
     CDS             complement(6899..7924)
                     /locus_tag="KB927_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6840783.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTVTLFFPIL
                     NFYNEKR"
     gene            complement(7942..8616)
                     /locus_tag="KB927_001867"
     CDS             complement(7942..8616)
                     /locus_tag="KB927_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6840784.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8800..9693)
                     /locus_tag="KB927_001868"
     CDS             complement(8800..9693)
                     /locus_tag="KB927_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6840785.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9767..11464)
                     /locus_tag="KB927_001869"
     CDS             complement(9767..11464)
                     /locus_tag="KB927_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6840786.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11457..12770)
                     /locus_tag="KB927_001870"
     CDS             complement(11457..12770)
                     /locus_tag="KB927_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBB6840787.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12770..16288)
                     /locus_tag="KB927_001871"
     CDS             complement(12770..16288)
                     /locus_tag="KB927_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBB6840788.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16581..17039)
                     /locus_tag="KB927_001872"
     CDS             complement(16581..17039)
                     /locus_tag="KB927_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6840789.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
BASE COUNT         4826 a         3851 c         2962 g         5498 t
ORIGIN      
        1 cgtataaaaa agagcataaa acaaagtcgt ttgttttatg ctcttctttt attattttgt
       61 gctttttatt ttatcaaatc actttgtttt tttataaaat ttctgcgcct agtgtggact
      121 caaaatgtct caatgcccat tcatgtccaa cgggatcgaa acttgccacg gcatctttga
      181 aaatatggag tttgtatcct agattatacg catcgactgc tgtatgcaac acacagatat
      241 ctgtacatac gccggtcaaa taaatatctg tgatctggcg ttctcgcaaa cggatgtcta
      301 gatctgttcc actaaaagcg gaataatgcc gtttgtctat ccaataaaca ttttcctctt
      361 gctcatagtc ttggtataaa ctttttaaag agccgtacaa ttcccgtcca cccgttccta
      421 tcacattatg cggaggaaat aagcggttct ccggatgaaa ggaatctttt ggatcatgcg
      481 catcaatggc aaaaacgaca aaatcctttt gatcaataaa cttctttgta tgagcagtca
      541 gctttttttc aattacttgt cctgctgtcc cagtagtcag ctttccatcc tctgcaacaa
      601 aatcatatgt gtagtcaatc gagatcaatg cgttcatctt agtcctcctt atacgagatg
      661 tttgacaaat tcgatcacca tttctgctga tcgtttgcct gcgtcttcga taaattcgtc
      721 aaagctttgt gtcgccgagt gatctgctgt gtcgctcatt gcacgtacga tcaaaaatgg
      781 gatattgaac tgacgagctg tttgtccaac agcggctcct tccatttcgc aagctaatgc
      841 ttcagggaaa ttcgttaaga tttctttgat tttatctggc gagtcgacaa atgtatcacc
      901 tgtaacgatc aatccttctt ttgcgttcaa attcgttgct tttgctgctt taaccatttc
      961 actgcgcaaa tatgtgcttg cttcataata tagaggcatt cctggtaatt gtcctgggtt
     1021 gtagccaaat cctgttgcat ctgcatcaaa ataagctact ttgtctgata taacgatgtc
     1081 acctacttgt aagccttcac cgattccgcc agctgaacct gtattgatca ccatgttcac
     1141 gccgtattgt tggatcaaca gacttgtggt aatagatgct aagacttttc ctataccgga
     1201 acgtacgacg atcacttcgt ggttacctaa tgaacctgaa ataaataaag cgcctgcgcg
     1261 ttcccatgat aatggttcgc ttaggttctc tctcaaaatt tttacttctt cttccattgc
     1321 gccgataata ccgattttca tctttttaat tccttctttc tatataaatg cgattgctaa
     1381 aaaaaccaca cataacatta ggataacaat aataagagat ttcatcaaaa aagagttcca
     1441 tttggtcgtc ttttcccgtt cgctgatcct tgttttcgtg attggtttat tctttttgct
     1501 ttctttacga taaaagctgg caatcttttt ttcttcttgc tgataagctg tttctgcttt
     1561 tcgctgtttt tttaatgact cgcttgcttg tgcttgttgt cgcttgcgaa gttcgcttcg
     1621 cgtaataagc ggtcctttgg ccataagccg atccctctac tttcctttgg tcaatagttc
     1681 ccagtattga atcgcataaa tcgtctttgc atcacaaatc aactgatctt tcatcgcttg
     1741 ttgcgcctct tcaagagtta gatgatacaa ctccagtact tcgtcttcat cttgtgctaa
     1801 aggattctcg accttctcta ccccttgtgc atgataaata tgaaggactt catttgcaaa
     1861 acctggtgaa agatacatcg aagtaagatg gctcagcgac ttcgcacgat agccagtttc
     1921 ttcttctaat tctctagctg ctgtcatttc gggattttgt ccttctcctg gatcgatttt
     1981 tccagctgga atctccaaaa tcactttttc taaaggtttt cgaaattgtt tgacaagaag
     2041 cagacgatct tgttcgtcaa aagcaatgat cccgacaccg ccaggatgaa ataccagttc
     2101 tctcttcgaa gttcctccat ctggcaaacg aacttcgtct acagcaacat caataatttt
     2161 tccgctatag atttctttgc gactgattgt tttttcttca aattgctcat tgttcagcat
     2221 atcttctcct gctttctttg taatcataac tgcttttttt tcatttttca atttttctca
     2281 aaaactcctt attagtttac catagataaa ccttagattt tctctaaata tagaaaatcc
     2341 ttctttagtc cgatactctt tatagtagtc cgtatgctaa aataagtatg taatcgaata
     2401 acgaaaagaa ttcaatactc aacgataaat gacatggagg gtttattatg ataaaacgaa
     2461 attggccgtg gcttctagca ttggtcttgc tatttctctt tgtccgaaac aatagttttt
     2521 cttttgttct aggactttta ttgataggtg tagttttagt tttgtgggga ctctttggtt
     2581 cgcgcaggaa aaagggaaaa caagaagaaa ttcctgcact gactgacgaa cttgaaactc
     2641 actatgaaaa aagcggtatg acagcgaatg aaatttcatt ttttcgacaa acaatgaatc
     2701 aaacaaaaaa tgagatcaat caattgcaaa tgaatatgca gcagacagcc aaacttaaag
     2761 caatcgatct ccgccatgat ccagtcaaag cagcgaaagc tttattcaaa gaattggtga
     2821 aagaaccaaa ccgactgcat gaagcaagtc agtttcttta tacgcatctg ccgaatctag
     2881 ttgatttgac aaataagtat aatgagatca atgaccatga gatcaaaaac aaacagacct
     2941 atgaaaaact agaagaaagc gcgcagatca tcgaccagct gtcagcttta atcgcacaag
     3001 attatcaaaa attcgttgct gaggatctag atgatatcga cgtagagata tctgttgcga
     3061 aacagagctt aaagcgtgat aataaatatg aaccagaaca aaaggattaa ctcttttgtt
     3121 cataaaagaa gactcggaac attcagatga tgtctggctg tttcgagtac tttttctaaa
     3181 gtagagacat tcatgtaaga atcgagaaca gattcaacaa ggaggaattt tttatggatc
     3241 ataaaccgac tgaaacaaaa gatgttacac cagttaacga tacacttgaa gatttattga
     3301 acaacccgtt ttcaactcca acagatacgc tgaccacttc acaacaagcg gagattgatc
     3361 agctccaaga gcaacagaca gctgctcgtt taattgacaa actaccggcg gaacgccaag
     3421 aacaagctaa acagctagca gcaaaaatcg atgctaatga tgcacagtct gtcatcagct
     3481 acggatcggc tgcccaagca aaattaagtg aattctcaca atcgatgttg aatcatgtgc
     3541 aagcacaaga tattggtcct gtaggagatt ccttaactga actgatgtat cgtctccaag
     3601 aagccaatcc tgacgaactg cgtgccggag aagggaacat cttccagcgt gtcttcggga
     3661 aggtcaaaca atcgatctat gaagtgacag caaaatatca aaagattggt gcacaaattg
     3721 acaagatttc agtgaaatta gataaagaaa aagacggtct gctaaaagat aatctgatgt
     3781 tagaacagct ttaccagaaa aacaaagact actttgatgc actgaatatt tatatcgctg
     3841 ctggagaatt gaaaatggaa gaacttcaaa caacgatcat tccagaagcg atgaaaagag
     3901 cagaagaaac tggcgatcag atggatgttc agattgccaa tgattacacg caattcctag
     3961 atcgtctgga taaacgtacg catgatcttc gcttagctag acagatcacg atccagcaag
     4021 caccacaaat ccgtttgatc caaaacacaa atcaggcctt ggctgaaaag atccaagcat
     4081 ctatcgctac agccattccg ctgtggaaaa accaagtcgt gatcgcattg accttgcttc
     4141 gtcaaaaaga tgcagtaact gctcaacgcc aagtctctga aacaacaaac gacttattga
     4201 agaaaaattc agaaatgctg aaaatctcag ccatcgaaac agcgaaagaa aatgaacgtg
     4261 gaatcgtgga tatcgagacc cttcaaacca ctcaaaatga tttgatcgaa acaatccaag
     4321 agacattgcg tatccaaaaa gaaggaaaag aaaaacgtcg tcatgcagaa gtagagcttg
     4381 gacacatgga agaagatctg aaacaaaaac tgttggattt aacccaatag atcacctttc
     4441 gcttgttact aaaacaaacg cccaacaaca gtttattaca actgttgatg ggcgtttttc
     4501 ttatctttct tctaacttct ccattggagt ctatttctca ttcatcttgc tgtgtccata
     4561 gccatagcca aaataaatga tcagtccaat aaccattacg ataccgaaca cgatccatgt
     4621 cacagtttgc agacgaagca tcaatacaat acaagtcaag atggagacga ttggcaatag
     4681 cggaacgaat ggcactttga attctccagc ttttggtttg ccaaacattt ttctcaactt
     4741 cagtaagcct agactaacaa gcatcaaata ggcgagcgcc atgatattcg ttagttccgc
     4801 taatacattc aatgggaaaa atccggcaaa gaatacagct gccacaccag cggcataagt
     4861 cgcttttttc ggtgtacgat gcttttgatc gatttctgtc ataaacttag gaagtaagcc
     4921 atccttgctg acagcaaaca gtaaacgagc aagtgaatac atcatcgaga tcgttaccgt
     4981 cagtagcgtt aaaattgccc ctacagcgat caccgcgccc actgttccat gtcctacata
     5041 cctcattgca aaagccactg ggtcattgac tcctagttca gtatacggaa cgattcctgt
     5101 caagatcagc gtcacgatga tgtaaaggac agtagcaatc agtatcgaac caatgattcc
     5161 tcttggcaca tctttttgcg ggtttttgac ttcctcggct gccattgcaa cggcatcaaa
     5221 tcccaagaaa gcaaaaaaca caagagctgc accatctagc acaccggaaa aaccaaaagg
     5281 catgaatggc tgccagttat caggtttaac gaaaaatatt cctacaatga taaacaacgc
     5341 gatgatacca aatttgacat ataccatggc attattcaaa cgtaatgctt tcttggcttc
     5401 aagcgacacg atgtaagtga cgaatatcac tacgagcacc gcaatcaagt caatgtatgt
     5461 accattttcc ggattgtacc cgccagttaa tgcttgtgga agttcggccc ctaaactttt
     5521 caaaaaacct tgcatatagc cagaccatcc ggaagcaaca gaggaaaccg ctagtaaaaa
     5581 ttccccgatc aacaaccacc ctgtcagcca ggcagcaaat tcaccaaata caacatacag
     5641 ataggcatat ggcccaccaa tcactggcac tcgcgaagca aattctgcga aacttagtcc
     5701 agacaaaatg acaacgattg cagctaagac aaatgaaagt gacagtgctg gaccagcatt
     5761 ttgattggcc gcaacccctg tcaccacaaa tattcccgta ccgatgatcg caccaattcc
     5821 aagcatgatc aaatcagacg tttttagttc ttttttcatc tcactcgtat gattgagatt
     5881 gatctctttc ttacgaaaca aatccattga agttcctccc cattttaggt tggaaaacag
     5941 cgattaaact gttttcatat accctaaaag gataccacct aaaatgacta aaaggcaacc
     6001 aacaataaca taaatgagct cttttttcgt ttttctttcg ccaaggatga aaatcccacc
     6061 taaagtagag ataatgatcc ccatttgtga aagtgagaag ccaacagcta aaccaagtga
     6121 tttgactgtt agaagcatgc agatgtttcc taagccccat aataatccac agatcatgtt
     6181 tttccacaca aactgatcga ctttaacttt acggaaagca aagaagcttg cgcctaagat
     6241 cattccgata ctttgaggta agataattga catcgcatcc aaattcgccc agttgacgat
     6301 gatggtatat acaccataac caatcgtaga gaagatcaat gctctaaaac ccttaccaaa
     6361 atcaagcatt ttattatctg tatctatttt tccttcgtca tcttgtcggg cagtcaaata
     6421 cgcaccgctt acaagaagag ctaaagcaat aataccgtat acataatctt tcgtttgtgt
     6481 ccattcatgg aagaaaacgg ctcccgcaat cgtattcaaa attaattgaa aaccagtaga
     6541 caatggtagc cctacagaaa cacccatgta cttcattcca tggaactgtc cattttgtcc
     6601 aacactccaa gctaagccgg ataaaaatcc gatcaagaaa atccaagggg tgattacagg
     6661 actaacaacg aaaaagacaa ctaaagaaaa cagaaatgca ccgatcgtca ttcctagtgt
     6721 ttgttgattg gcatcgccac caattttacc acttactaaa ccaatactac cccatgccaa
     6781 catagggact aatgctatta aaatttccat aaccaatctc cttttatttc acatgataag
     6841 aaacttatca gcgaaaacgt taacaacaca agcacttttt ttcgtttcta acgattttct
     6901 aacgtttttc attataaaaa tttaagattg ggaaaaataa agtcactgtt gtcccttttc
     6961 cttcagttga ttcagccgtc aaatggatac ctaatttttc ggccagattt tttgctaaat
     7021 aaagtcctaa tcctgttgaa tgtgttttgc taagtcgacc atttctccca gtaaatccct
     7081 tatcaaagat ccgtttcaag tcttccgctg ggataccgat ccctgaatct ttaactgaaa
     7141 ggctgactcc ttgcgcttcc ttttctatgc tcacaatgat gtttccgtga tccggcgtat
     7201 atttgatggc attactaagc aattggttga agataaaagc gatccattta gcatcggtca
     7261 aaacagtatg atcctcacca acgatctcgt agcgaatatt tttttggata aaataatttg
     7321 cctgactgcg tatcacaggc tgaatgattc cttttagtcc atattcttgg atgaggtagt
     7381 cccgcgagaa actgtcgagt cttgcataat acaaaacttg ttctacgtat tcatcgattt
     7441 ttgataattc attttctagt aatgtatact tttgatcgtc aatatcgaac tcgatcgaac
     7501 gaactagcaa tttagaagcg gaaagtggca ctttgatttc atggacccat gagtcaatat
     7561 aatctttttg gtcttgttga ttactgattg ctgattgcat tacttcttgg tgttcacgga
     7621 tcagctgatt gatatattct tctaccagtt tttcttcttc tgtcctccca ccactcaaat
     7681 aattttgcaa aggggaagtt ttttgtatgt cggctaattt tccccaccat cttctcttgc
     7741 tcaagtaacc acccagcaga taaaaaatca gaaagacgcc ctcaatcaaa gctaaataag
     7801 caattgtgct caaatcaact ttgatgtttg gcgccagcca catcacaaag atcgtcaatg
     7861 caataaaaaa cagccatccc aagatcaatg tccactgatc tttcaaatat ttaaaaaaat
     7921 tcatcttaac cgctcatcct ttcagggaac gatatatccc tgtcctactt ttgtttcgat
     7981 atatccttgg atacctgcct gttcgatttt tcggcgtaac cgattgatgt tgactgtcaa
     8041 tgtattgtca tctacaaatc gttcgtcatc ccacagtgct cgcagcaatt tttcccgact
     8101 taagatcttt ccattgtgct tcatcaaaat aaataataga cgatattcat ttttgctcaa
     8161 atcaatgatc tctccgttga tttccatact tccgttgtca acattcaacg taatgccatt
     8221 gtggctcatc atttcactag ataattctgt gtagttgtaa gaacggcgaa gtaatgcatt
     8281 gatttttgca atcagtacat cgatttggaa atgttttgtc acaaaatcat ctgcccccat
     8341 gttcatagcc atgatcatat ccatattcgt attcctgctg gagataaaaa tgatcggtac
     8401 tttcgatact tcacgtattt tttgacacca ataatagcca tccaaaacgg gaagattaat
     8461 atctagtaat acaagctgtg gttcttctct ttcaaagtct gagaacactt gattgaaatc
     8521 ggtcgttcca aaggtttcaa attgccattt ctcaagttcc tccatgatca attgtcgaat
     8581 gatctcttcg tcttcgacta ccatgatttt tgccataaaa aatccctcca tctttcttct
     8641 tgctactaca atatcaaaga agcccttgtg aaacaagttg gcttacctgg aaaatgtcat
     8701 tttagcaaac gttaaaaaaa actggaaata tgcgatttaa tcgcgtttgt ctcttccaag
     8761 cagcttaaat ttattatgtt attcttaata attggtctat tatctgttat ttttctttcg
     8821 ttgtttttgt cttttaaatt ttcgataaca ccaataaccg aaaagcgtta gcactagcaa
     8881 tatacctaga aggagtataa gtaatcgata aagatggtat ttttttgtct gttctatctt
     8941 tgaagagact tcttctgtaa agggaactcg tcttcctgtc actagtaatc ggtgagtgtt
     9001 cacggtgtaa ggtgtacaag tgataagtgt gactagatcc tgcttttctc taattgctaa
     9061 tgtatttgtt tttgttggaa ggacaacaat tttctcaacg acttcataag cgagcatccg
     9121 accatacact tcaagataga atcggtcatc ttgctccatt tcttcaagat ccgtaaagag
     9181 ttttttctca gcaataccgc tatgggcggt aatcacggaa tgtgtactct ctcctccagt
     9241 tggaaaagag gtgccttgca ggactgtcgc tcctctatct aacaaaagat cattcgtttc
     9301 atcaaataaa ggcaagctaa cattgatttt cggaatatag atggctccga tcatatgttg
     9361 ttcgtaatat tcttttcctg gattttggac atttctaacc gcttgctcaa aaggatcttt
     9421 gacttgtccc attcctggga ttactgatgt atgagcaagc gtctgatttt tcttttcatg
     9481 cactgctaat tgttgctcat gtttttcttc tttatcgcgt tcaagctgct tttgataatt
     9541 ctcgatcctt ctttgatcca aataattgct gagagcatct gctaaaaatg gatatgtaaa
     9601 aactgcagct ccggcaagaa acatcactgc cataaataat tgtaataaaa gactgatttg
     9661 ggtttgaggt ctattaccta ttttcttttt cattttcttc accttcttat ttaaaaaaac
     9721 tgcagcaacc tttataaaac cgattgctgc agcttatttt tgttgcttat acttcagact
     9781 tcattttaga tttacggtac cagctgtacg ctccaatcat caaacttatt ccgattagta
     9841 agaatgccaa gagcccgttc ccaccagtag caggaagtga cccgcgtttc atattcggta
     9901 ctctttctgg ccctggattt tctactccta cgatctgaat ttcttcatta tagcttccat
     9961 aagagatgat aaattcagta aaggctgcct cacctgttgg aagtacataa ccttctggcg
    10021 ccatggtctc tttcatttga taggttccat aatctaaccc ttgaacctca aagtatccat
    10081 ttccatctgc gacaaattct gttgcttgtc cgcttgttgc ccactcaatt ctatctgctc
    10141 ctgattcata aacagctaaa ggcgactccc ctttataaaa tattgcgtat tcagaacggt
    10201 cttcattcca caattcgaat cttgcatctt taagcaattc actgcttgat gcatcatatt
    10261 tttcaaactt tcttccacct gttgtgactt tctctggcgg ctctactcct tcttcataat
    10321 caaattcatc atttcgtccg atttcaataa ccgctgtgtt gttatggaaa tcatccgctt
    10381 ctagttctgt ggaaaccttc aaattatacg tgatcgttaa atctcctcca cgtgcatctg
    10441 ctaatctacc taaagtatct actttggcta ctccattttc ttctgtcaaa atcgtcacga
    10501 caaacccgtt gcttactact tctactatat aatcttgtcc ttttgttaaa atcgtctcgc
    10561 cggctcgcac ttctatttcc tgatcataat aagttagacc aactgtaggc gtatctgtga
    10621 ttttgtaatt tttgataaca gcgcttccgt tttcaaggac agaatcgatg aaataaggaa
    10681 taggtgctgt gatcgtgtaa gaagccgttt ttcctctttc tagatcaata taagaaatcg
    10741 tttcttgttc tccagcttca ttaataatcg ttacttgtct aaggtcgctt tcctctacat
    10801 tcatctgttt atctgcttct ctgatttcgt ttttcggata caaatgcaca tctgtattgt
    10861 atgtgtcttt ccatgtagaa ccatcccaca cgccatccac catatcaggc atcatcactg
    10921 gcatcataac aaccattgga gacgcgattc tggaaatatg agctggcgaa taagtttcta
    10981 agaaaagata gactttatct ctagaagaag gtgcttcttc cgtcacttgg acggtagaga
    11041 ataccgcttc tccagcttca ttcgttgttt gtttgtcaat acttgtcagt cgatatttta
    11101 aaaaccaact ttctgtgtgc cgtttttgaa tccattcaat cgcttcggca gaattaagac
    11161 cgtcttctcg ttccggtgtt aaaggattat ctcgaatcaa atcgtaatat acttccgtta
    11221 cgtcaaacaa atcaaaatcg actcctggaa tattttcttc accaaaatcc gtagaaacca
    11281 atccgctatt cggtcgttct tccggaacag atgagaaacc ttttttgtgt aatgtaatcg
    11341 tcacttcact tggtttttgt gcgacttctt cggctttgac tagttttccg ttcccgaaaa
    11401 tccctattcc cgcagtaacg agtaacagta cactcattcc cgtgacaatc atttttttat
    11461 tcattttttt ctccccgttc tttttttatt aataaaacag cacctaacaa taaaagaatt
    11521 cctagtaaag aaatcaacgt tcttgcttca ttcgtttgcg ggaatacgga ccattttcct
    11581 gattgacctg gattgcttgg accactcggc tctttcggtt tgtccgttgt ttcttttacg
    11641 gtctcgttat aaacacgtgg tgttgcggat tcataggcag agactggaac tttcccggat
    11701 tctaattcag ccatctcctg tccgttaact actacatatt gtggttggcc ttttgcatcc
    11761 acccaaaatt cagggatgat gacctcgatt ctcttacttg cttcatccat ctcgtaacct
    11821 tccacacctt ttaattcttc aaaataatag gtgccagaag gcaagaaacg ttgtcctgtc
    11881 gtaacaaggc cctctttatc cgaaatgaat ttgcttacat ttttgtcatt caaaggatca
    11941 ttgtctgctg gtttgatcca ttgatttttc aagtcattag caggagccat atctaaataa
    12001 tatttccccc cttctatcat ctgatataga gcaaaaacag caccttctaa tggttttcct
    12061 ttttcagttg ttcctctttg acgtccatac ttgaagaagt atggatctct tagataaccg
    12121 acatttttag gatagatatg aatctcttgc agttcctcgg ttgattctgt cgggtgataa
    12181 attggcaaaa tagcagcaat tgggatagct gtctgatcga tatcaacatc caatccaact
    12241 tctggatcaa tcgattcttc gaaaatcaaa taaactgcat cccgatcttg gtttttctta
    12301 ggtgctttga tacgtgcaat cccgtctcct aatccgccaa ccgtatcttt cccagttgtt
    12361 accgaagtcc ctatttggac aagcctttct tctgtgatta gctgacggat attgtttctg
    12421 ttcgtttcag cgatttgctg gacgaattct ttaggagtca tgttttcagc agcttttttt
    12481 tcatgataat aatcggtcat gtcgtaaatg gcaaatgtcg ctccatttag tggcaccgtc
    12541 tgtgaaatga tatctgctgt ttcccctgct tcctcagaga tagccaagcc atcattttca
    12601 tggtattcaa attgatcgtt ataatcgata tctcgaatca tccgtttatg caacacgaat
    12661 tccacgacat cttcccctga ttcttctgcc gacatcgcat gtggaagaag gactgctgca
    12721 agcggtagta aaacaagtaa ttgaagcatc aaacacaaca gctttttcat taccttgctc
    12781 cctccttttt agattgtctg acaaacaaac cataggctgc tcctgcaagc gccatgaaga
    12841 atgcagcaag caggatatag aataatcgtc cggatcctcc tgtagcaggc aacggatttt
    12901 caggatcgtt cccgacacta agctgtaatc tgattcgatt tgtctccaaa agttcatatt
    12961 ctaactcttg ctgtagatca ggcgtctctg cttcttcgtt tggataatac gaaatctcaa
    13021 cttttagtgt acccgcttct tttcctggaa ctacccgatc attttctatg tcaggttctt
    13081 ctcgataact aatttctaaa ataaagtaac ctggaagttt tctatagctg tcaggtgact
    13141 tcacttcctt gatccgatag accccttcca acaagtctga agcattgaat agggaagaat
    13201 cgtttggatc tggtgccaag cctccctcga tgatttcata ctctcctgca ctattttgtt
    13261 tctcaattga aaattctgcg ccttcaagac gtcggctatt catactgtca attttcaaaa
    13321 gttccaaatc gattggcgct agttcatctt ctaaggttac ttgtagtaca ccatcgatga
    13381 tttcatagcc ttccggcaag ggagcagttt cgtcttcgat gaccgtatct tcaatgataa
    13441 acttaccttc ttcattcagt gcaaactgga acacttgatc agatagccga tacccatttg
    13501 gtgcgacaga ttccgagacc tcatattcac caatagacag atgcagaggt tggtcgtaat
    13561 ttaaatcgac atacttttct actcctacgg cacgagaata gaagtatccg atcccaggca
    13621 aacgtttcga ttcttctggt tctaacggat taccagtgta tgctcgatac agcgggaagg
    13681 aagaatcccc cactttcctg atatcgaaac ctgcaccatc taatgtatgg ccttcatggt
    13741 ctaattttct aactcggatc tcccgataat caaacgtatt gtaagcagtg aatgctaccc
    13801 ataaacgatc ctcttcatct gttgtatacg tgagatattg ccaattttct tcacctgttt
    13861 gcttgagttg gatagtccct atagcattat cgtaaagtcg caagatccat gtgtcatttt
    13921 catcaggttc tttgaaacct tctgggttct ggctctcaat gattttgtat tctgcatagt
    13981 tggtagtttc ttcactatcc ttataaacaa atgaatctgg ctctccgatt ggatgaataa
    14041 ctttctcacc atccacgatt acatatttcc cgtcttcatc tactgaatag aacgtgagtc
    14101 tccctttctc ttcctctact tcgttcacac cagaaagccc tttcgctact ggatatccga
    14161 tttccagtcc gttaccatct gtttcataaa gttcaaactc tgcgccattg attggcatat
    14221 tactgccttc aattagttta ttgatattca tgtggattgg cttgaattca tttcgcattt
    14281 ccagtttgac atacaactca tcatactctg tgccttctat gttaggctct tgtacaacag
    14341 aaagcttgtg atattctcct tcataatagg aattcggatc tttaccttcc ggtccgccga
    14401 ctctcgaacc agatgtatat tcatctacaa gctcgtagtg acctaacatc tcatcttcgt
    14461 tggctgcata ttttttgatt tggaattgat acgtctcatc tactaactga taacgtggtg
    14521 gtccagcgat ctctctgatc caaaatatgt cgctgactgc tccagtttca tctcctaaaa
    14581 tcggcatctt cgtttcaaag atcgctattc cgtccgtggt agttttactt gtttcgattg
    14641 gttcggcttc cccactctct ggattttggt catataatgc aaattcgact ccagccaacg
    14701 gctcgccatt ttgacccttc ttgctgactt ggaaattacg gcctttatgt tcgtaacgaa
    14761 tggaagaaga tgggaaatac atccgtccag tagtgatatc attctcataa tcctccaggt
    14821 tctgaatata ggccatattg ttcactgtgc aaaaatttcc gtcttgagct cccgcatcaa
    14881 gttttacttg gtacttgatc ctgaccattt ccccttcacc taaagaaatc ggagaaaatt
    14941 tataagcttg gttttcccgt ccgacatacg ttgtcggagt cgccactact tctggtgggg
    15001 cttgtccatg acgttcttca tcccatattt ctggctcttg gtacttcatg ccgttttctc
    15061 ctggatctag atggtaaaac tgaatatctg ccgatctgcc agctccaaat ggtgagacat
    15121 taaaaccagt ttcatcataa agtgtggctt gctggatcgt tctcttgaag gtagaagaga
    15181 tatcctccaa ggctgtaaca atgtcattct tgttgttcgc attgtaatat cgcggtgtta
    15241 cgccatcttc ttctaaatca gcaatatttt tcaatacatt tcgtccaata gcatctagtc
    15301 gttgtctccc gctaacgttt ccatcgattc ctaaaccaat ggagaagata cttggcgggt
    15361 tctcttgata cttgtttttc agccaatgat gataagcaac tgtgttgatc gcagatgact
    15421 tttcttgcga agtaggactg ccattcgtat tgttattaga agaaccatca ccaacccagt
    15481 gagtcgcttt attatctcct tcttttacct ctccataacg atagtgtaca tttacttcat
    15541 cttctggacg gttaaagtca gatgcatagg taactggatg agtaaaccct gcattagaag
    15601 tattcccaga aaactcctca aaatttctga acaaaacgtc attatcttca gcaatcttat
    15661 cttccatcac agtccagttg ctccaagctc cattagtgct cgtacgataa cttgactgaa
    15721 tcggtgcata actgaaggtc ggtgtcccat ctcccacaac gattaggatt ttttctggat
    15781 ttctattttc tccgccattg tctttataca atgtttcata gccattttta agccctagtg
    15841 taagcggagt tcctccgatt ggtgtacgat ttaatgctgt attctcactt cccgtcaaac
    15901 gattgatatc atttgtcaat ggaaagatgt ccgaactgat ttgctcatgg ttattgatag
    15961 ctgtactatt atggtaaaaa ttcaccatac cgattcgaat atccagactc gggtcagaga
    16021 gcagatcttt actcatttcg tttactgcct caatcaacgc agcattttta gtttgactat
    16081 tggtcccagc ggttaattca ctcatactcg ctgacttatc tagaacaaaa acgatatcga
    16141 ttggactgat ttcctttttc tcgcccccga tgacatctag atagacattg taaagggttg
    16201 ttgcatcttc aggatgtaga tcagatgctg tgctgcttgg cagaacaggt tctacccatt
    16261 ttttgatgta cgccccgtta taatccaagt aactgttttc aaaattccgt tcatttcccc
    16321 aaagctgaac ggtttgagct ggaacgtttc tatcttcttc gcctgcagtt gatccattat
    16381 tagtagcata gtcgtaattt cgccagttcg ctcccccgtt tgtataatca ctatcatcga
    16441 tcaagttctc tccgtcatat ggcgagcctt tgtctccttg atagcgttca ttgctttgtg
    16501 tccaatttcc taacactttt gtatagtcat tcgttgtaaa cttcatctat tctttcatca
    16561 accaccactt gaagaggtag ttacccttcg ttcacatcgg ggatcttttc tgtttcaaaa
    16621 atcaatgtgc cggtttctgc ttcttttgaa taaacttttc cgacatacca ttcttgacca
    16681 tcgatcgtct cgacttttag gtcttctcca tcttcatcat aggaggatag acctgttcca
    16741 cgaacgtttt ttacggtacc aatcccggcg gctgccgcat cgattgctaa acgtattcta
    16801 ccttcattgg cactttcctt tttttcaaaa gccagatgcc attcaagggt ttcttctttt
    16861 tcaatatact tcccttcaat ttttgcatag tcctcatcta agaatacctc atcctccttt
    16921 gtttctgttg actcagcagc tacatccagg gtcgtcatat gatagactga ctggaaatat
    16981 ggtccaaata gcaaactgac agttactaac tgcaaaagct tcaattttaa ccctttcaca
    17041 tccttatact cctttcaaaa atatttgtct tctttcacaa caatcaacaa aacaatgccc
    17101 atctaattat aatttaattt aattttaatt ttaaatc
//
LOCUS       DADVXM010000054        16446 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.057, whole genome shotgun sequence.
ACCESSION   DADVXM010000054 DADVXM010000000
VERSION     DADVXM010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16446
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.057"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(152..550)
                     /locus_tag="KB927_001873"
     CDS             complement(152..550)
                     /locus_tag="KB927_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBB6840790.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(547..1320)
                     /locus_tag="KB927_001874"
     CDS             complement(547..1320)
                     /locus_tag="KB927_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBB6840791.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1317..2000)
                     /locus_tag="KB927_001875"
     CDS             complement(1317..2000)
                     /locus_tag="KB927_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBB6840792.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2167..3054)
                     /locus_tag="KB927_001876"
     CDS             complement(2167..3054)
                     /locus_tag="KB927_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6840793.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3051..3920)
                     /locus_tag="KB927_001877"
     CDS             complement(3051..3920)
                     /locus_tag="KB927_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6840794.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4057..5343)
                     /locus_tag="KB927_001878"
     CDS             complement(4057..5343)
                     /locus_tag="KB927_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6840795.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5616..6194
                     /locus_tag="KB927_001879"
     CDS             5616..6194
                     /locus_tag="KB927_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6840796.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6194..7123
                     /locus_tag="KB927_001880"
     CDS             6194..7123
                     /locus_tag="KB927_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6840797.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7120..8856
                     /locus_tag="KB927_001881"
     CDS             7120..8856
                     /locus_tag="KB927_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6840798.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8919..9755)
                     /gene="pheA"
                     /locus_tag="KB927_001882"
     CDS             complement(8919..9755)
                     /gene="pheA"
                     /locus_tag="KB927_001882"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBB6840799.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9752..10261)
                     /locus_tag="KB927_001883"
     CDS             complement(9752..10261)
                     /locus_tag="KB927_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBB6840800.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10254..11549)
                     /gene="aroA"
                     /locus_tag="KB927_001884"
     CDS             complement(10254..11549)
                     /gene="aroA"
                     /locus_tag="KB927_001884"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBB6840801.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11562..12653)
                     /locus_tag="KB927_001885"
     CDS             complement(11562..12653)
                     /locus_tag="KB927_001885"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBB6840802.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12670..13836)
                     /gene="aroC"
                     /locus_tag="KB927_001886"
     CDS             complement(12670..13836)
                     /gene="aroC"
                     /locus_tag="KB927_001886"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBB6840803.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13838..14902)
                     /gene="aroB"
                     /locus_tag="KB927_001887"
     CDS             complement(13838..14902)
                     /gene="aroB"
                     /locus_tag="KB927_001887"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBB6840804.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14935..15957)
                     /gene="aroF"
                     /locus_tag="KB927_001888"
     CDS             complement(14935..15957)
                     /gene="aroF"
                     /locus_tag="KB927_001888"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBB6840805.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
BASE COUNT         4753 a         3630 c         2918 g         5145 t
ORIGIN      
        1 gcatattttg aaaagaaagt ctgatgctta gagtagaatt tcataaaaat ttactatttc
       61 ataagtattc acgagaaaaa tacaaacaaa aaagcggaaa taacgctcat ccgccttctt
      121 gtttgtgttt atttcctctt caaacgcttg tctatgattc agacttttct ctatcgttat
      181 tttcatctaa aagttcttgc attccgataa tttctcgata ttgatgaatc ttagtgatac
      241 caatgacttt gtctacatca atactaaaac aaataccatt acctggaata tcgatgttga
      301 tgccttgacc aatcgcatcc attactttat tcgtcaaact atcgggtact aatgtcaaca
      361 caatatcttt ttctggcgaa atgtccaaac ctaaaaattt ccctgaatca tgtacaccag
      421 aacctcttcc atgtaagatc gttccgcctg ctgcacctgc ttcttttgaa aagtcgataa
      481 catcttcgcc cattcctccg tcaacgatcg tcacaatcat gtgaagattc aatgctacaa
      541 gatctttcat ttgctttccc ccaatttttg caatctttct ttttcgattc tgtctttttc
      601 atcttttcgt ttataaatat atcctagtac taaagtggat aatattggtg tcaatgcaat
      661 cattgcaacc acaccaaacc cgtcaatgat cggatctctt ccttcaattt gtgcagcgat
      721 tgccacgctc attgataaaa taaatgtcga acacatcggg cccgttgcta ctccaccgtt
      781 atcaaaagcc attgctaaaa agatcttgtc cacttttcgt cctaaaataa atgctagccc
      841 gtatcctggg atcaagaaat aataaagaga gaatccgacg agcaaacgcc acatagacaa
      901 tcctactgct gcgccgatcc caattgaaat taccatcagc atgattttcg atcggattct
      961 cccctcgctc aattcttcaa cctgtttgat cattacatga atcgccggct cagcaaaccc
     1021 tactaagaac cccattaaaa agccaagggg aaccagtata taattgtaag gcaatcccgc
     1081 aatagcactg cctaaatgct gtcctaccgg tacataagcc atattgactc cgtgcaggaa
     1141 aaggatcaac ccaatagtcg ttatcaagaa acctttcata atgtcaaaga aacgcttttt
     1201 gcgcatacga aaactaatga tattcattaa aacaaatagg attacgatag gtgccactgc
     1261 caaaatgact tccatggtaa cgatttcgat tccatctatc acttgctgcc agaaactcat
     1321 tggaagatca cccccaaaat catcacggca agaatcggcc ctaacgaagc aataccgacc
     1381 attccaaaac tgtcattttc atttttcttt tgtttgatca tactagtcat ccctccggca
     1441 agggccaaga taaatggaac agttactgga ccagtagtca ctccccccga atcaaaagca
     1501 atcggcataa attcggaact ggtgaaaaat gaggcgatca aaacgcctat gtagcctata
     1561 gccatcaatt gataatagga tagcttgaat acgacccgaa gcagcgcaaa ggctagaaat
     1621 actccagtgc cgacgctgac gatcccaatc agcaacactc tgccaatctc tccgtcagat
     1681 atatcatata cttgttgtcc caaaacttgc acggaaggtt cagcaatcgt gatcacgatc
     1741 ccgatagcaa atcccaaact gaccaaaacg gtcaaacttt tctttttgat catatatttc
     1801 cctactagat ctccgacttc catcatagaa taatctgctc caaacaaaaa gagcgtcatt
     1861 ccgatcatca tgattgccgc accaaccaga aatgaagcga ggtcttctcc ttctaacggt
     1921 gcaaaaacaa acgttaaaat gacaatcagg acagtcatcg gcaatatagc agcaatcact
     1981 tctttaaaat tttttagcat gtatcctcct cctttactct ttaagtttac cttaaaatga
     2041 aagagttttc gagcacaaac ttaaaacgtt atcatttaat ttttctcaac ataaaataac
     2101 acacgtccca aaagtatctt tttacttgga aaaatgactt tgaaggaacg cgcttattgt
     2161 gtttttttat tttacagagc cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa
     2221 tacgatggca gttggtaaag tagcgatgac taatccagcc atgatcattc catagtctgg
     2281 tgtataggaa gcacccatag cagataaaac aagcggaacc gtccgtttat caggagattg
     2341 caaagctact aagggccata aataattgtt ccagctactc atgaatgtga tgattgcagc
     2401 cgcggcatag gtatttttag ccgtcggcat atacactcta aaaaaaatac ttagttcttt
     2461 tagaccgtct aatcgagcgg cttctactag atcttttgga aaagatttaa cattttgtcg
     2521 aaagaagaag atcaaaaaag cagtgctaac agatggcagg atgacaacca agaaactgtt
     2581 gattcccaaa accgttccgt tcaattgtga aaacattcga tataaaggga tcatcaatgc
     2641 cgcaaaagga accatcatcg atagcagtag aatattgaaa attaggtctt ttcgtttact
     2701 ttgataaatc tcaaatccat atcctgccat tgacgaaatc agcaatgcaa acacagtggt
     2761 caccaaagcg atcatcgctg aattccaaag ggaacgagta aaattcagct cattggaaaa
     2821 caaattttga aaattgatga tcaagttact gccaatcttt atttttcccg atgtgatatc
     2881 cacgggtgta ttcgtcattc ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga
     2941 taggatgctt aatgctgtat actttaatac tgacccaatt gtcgaacgaa gttctaatgc
     3001 ttgttttttg acgttggggc gttcgattgt ttctttttct accatatttt tcatcgactt
     3061 tctcctccta ctttcgtttg gattatcgac aatatcacaa taaaggaaac aataacaaag
     3121 gaaactgctg ccgcatatcc aaaattaggc gtgaatttat aactcaaatt atagatgtat
     3181 tgagataggg tggtcgttgc atttgctggt cccccgccag taatattttg tacttcatca
     3241 aaaagctgca atgtcccgat cgtcgaagta atggaagtaa acaaaatgat tggttttaaa
     3301 tttgggatcg tcactttgat aaactgctgc catttagaag caccgtcaat agatgctgct
     3361 tcataaatct ccgaatcaat attttgcatg cctgaaagga aaaaaatcat attgtatcca
     3421 gtccaacgcc aagtgatcga aagaatgatc agaactctcg cccaaattgg atgagtcaac
     3481 cagccaatcg gtgtgtcaat cataccaatg cccaacaaca agttgtttac aaggccagat
     3541 tgagaaaata gacttttcat gatcagagaa taactgacca tcgaagtgat acatggaaga
     3601 aagatagcgg ttcgaaacaa ccctttatat ttcaactttt tatcatttaa aaggttggaa
     3661 ataaaaagtg ctagaaacaa catgatcggt acttgtacaa gtaaatacag gaatgtatta
     3721 aaaaaagctt ttttaaaagt tgcatctgtc aacatccgct gataattacc taacccgtta
     3781 aatgtcatat tgacaggggg accactttga aaagacgtga tcaaagccaa aaccatcgga
     3841 ataaaaacca tgattgatat caaaatgact ggcaagatta aaaaagcatg cccgtttttg
     3901 aataaatctt tctgcttcat tcttttccct ccaattctat cattgattat ctacatgaaa
     3961 agacaagaaa gacaatatct gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg
     4021 atgaaaaagc gaagaaattc acttttttac caccgatcaa ttagccaatt gtgcttctac
     4081 ttgtttttgt gtatctgcta gtaccttgtc tgtctcttct ccattgatga ttcgatgaag
     4141 agcttcagct acgactgctt caattgcata ggtctcatgt ccgtaattca cttctggtat
     4201 ttcagatgtc catgttgaaa aatcgtcaaa gatcttttga ccactgtaaa attcagaagc
     4261 ttcttgataa gcttcttgtt cattcgcgct aagcatcgta gatactagtc cgatttcttt
     4321 cgcaagagtg cccatcagtt cttcattcga agcaaacgtt gcttctagga aatctttcgc
     4381 tgaatcttct ccagctactc ctttgatcac ataccagcca gcgccgccaa ggttagaagc
     4441 ttgcgctttt tgcagatttt ctggaagtgc aggtattggt gcaatcttcc attttccaga
     4501 ttggttttct gctccttgga tcgttgaaga ataccaagcg ccagttgggc tagaagctac
     4561 tgctcctgat tgtatcgcag ttactccagc attccagtca gaggtttgtt cgactagatc
     4621 ttctttcaaa agagtggcaa acaattcaag accatacttt aaagatgcat tgtcttggat
     4681 cgtgactgtc tccccatctt cagatgtata ccattctcct gcctgttgca taatcatcct
     4741 tactcgacca aggtcagaag gattgacttc agcgattttc tttcccgtct tttctttgac
     4801 atctcgcgct acttgaatat actcgtccca cttcagattc tccatatcct cttctgtata
     4861 acctgcttct gccatcagat ccgtacgata gaagtttgct gttacgcccg aatcgaaagg
     4921 aacaccgtat attttatctc ctactttgtt taccgcaaat ttatacggtg caaaatgatc
     4981 ttcctttaca atagcagaca aattagcgaa tgcatctgga taagaagtca aatagccttg
     5041 tatcctataa tcttcaatca agacgatatt gggcaatcct tctgtattcc cgctcgctaa
     5101 agcggtgttc agtttctgaa cgatatcatc ctgagacatc gtaacaactt ctatctctgt
     5161 ttcttcgttc tcataaactt tttttgcttc attcactgct ttgatattga atgtctcatc
     5221 ccacgcccag acagtgactt tttcttcttt gtctgctgta ctactagcac ttccgcatcc
     5281 tgttaagaaa cctgatgctg ccgctaaaca aacgactcca gcaattaact ttctgatgtt
     5341 catttttatc cgctcctttt ccatccatta gttgtttacg tttgctacat tcatcatacc
     5401 aaaatttgaa aacggtttct ttattattca gatacttcaa aaatttctcc taaaataata
     5461 aaaaaataca aatcaactat gacaaaagga ataatcttag catctagacc aaagatcgaa
     5521 atggtgaggt ttctttaaaa taaaaatatc cttgcatttt ctcctagaaa taagtatttt
     5581 taaattacaa gactattctt aaggcgggta aaaaaatgcc aatacgcgta attcttatcg
     5641 atgatgaaca gacgatttta gatggaatga aacagttgat caattggtct gagcacgggt
     5701 ttcaattaat agggactttt tccagtccgc tgaaagcgct tgatttttct ttggtacatg
     5761 caatcgatat cgtggtcaca gatgtaatga tgcctgaatt aaatggaatc gaattatcgc
     5821 ggctattaaa acagcaacaa cctgaaacac agatccttat cctctctagc tatgatgaat
     5881 ttgatatggt taaagattct tttaaagaag gcgtcgctga ttatctttta aagcctcgat
     5941 tgagtcctga tttttttcta aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc
     6001 ccaacaaaag cccaatcacc aatcgttatg agcagatctg cgagaatctt tcacagcaga
     6061 ttgctggaca aactcgtcca ttgcttgacc ctcttctttt tgaacacacc ttgtttttct
     6121 gttatatacc gaaaaacggc cattcagttc aaaacaaggc tctaaacaaa aacagtcgat
     6181 cacccattca ttgatggata gcgacgattc gtttactatt tatcctgttt ctaccttttc
     6241 ggaagaatcc ggctatgtaa tcaatactga ttccaaagat acacttagga agtttgttca
     6301 aaagtttcgt caagaagttt ttccaggtga tttttttgtt gtttctgatt cttttgcaat
     6361 ccaagatatc aatgaaatat tccaagagat cagaaattgc accaaaggac aacgtttcta
     6421 tcataaggga aagaaccttg cttatcagca tgaacttctt ccgttattaa ccaaccacga
     6481 gcagcaagca agtagttatt taacaaaaat cgttcataaa gactacgctt tagctgtcaa
     6541 agaacttgag aatttcttca cgacgatatt ggaacagcct attgatccag cttatttgaa
     6601 acatgaggca atcaatcgtt tctatgcatt actcaacgct ttggctgacg agcatgttgg
     6661 gaatgaagaa ctttctttgc tcaagatcgc ccttccttct ttattagccg atgctgagta
     6721 tttcgaagat ttttctattc ttgtcaaaga aacacttgag aaactcaccc acttttctgc
     6781 aaatgcaaaa aaagacaatt tcgatatctt gactttgatc tacgagttcg tccaggaaaa
     6841 ttatgagaaa gaaatcaatt tacaactttt atccgaaaaa tatcattttt catatagcta
     6901 tctctcagcc atctttactg aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt
     6961 ccgtatcagt aaagccaagc tctttttgac ggaaacacgg cttactttga cggaaatctg
     7021 tgagaaagtc ggctataccg aactgggtta tttctccaga gtttttaaag aagagacagg
     7081 aatgacacct tctcaatacc gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag
     7141 catgaactct ttgccaaact tctgttcatt ttgttcatcg gtctttttct gcaagccatc
     7201 gtcatttctt tgtttattta tcatcgatca agggatgcct atatccagct gttcaatcaa
     7261 tcgaatgatg tggtactaaa aaagattcaa tctgaatttg aaagtttgaa tgatacaatc
     7321 gagaatacat tagccgcttt tgattctaat ccagctgtca aaagctattt ttccaatgat
     7381 ccagcccaac atatggaaca gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct
     7441 ctttcaaaaa tccatccaat gatcgattac gatgtattga tctttggaga aaatggaaga
     7501 acttttgtcg gaaacgacat gctcactgcc gtatctgccg attctttttt tcaatctgcg
     7561 attgctcaga gagtgaatga acgtgctgct gatacacaaa tgctttttgc acaccacgga
     7621 ttgactcttc gcgataagaa agcacccagc gtcttctttg tcaaaaaact gaaaaataca
     7681 ttgaatcacg tttacggata tgctgtttta tcgatctcat ccaagcaact agcgaatctt
     7741 tttcaatctg tagtaaatcc tgagatatcg aagatctcct tcatgaacga agaacagacg
     7801 atcatcgcat caaatgaaga aaatacaatt gggagccgat caatgatttt caaaaaacta
     7861 acagtaggtg aaacaacgat ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc
     7921 caggattgta cattactcag tcaagtcgat cttcattctt tatctaacca aatgggcgtg
     7981 atttttccga ttattttgta taatatcgtg acacttgctt ttgctggctc attggtattt
     8041 atgtatttgg atcgacacac aaaatcgatc taccgcttga ttgattcgct aaaacggcta
     8101 gaggaagatg gcttaaaagc tactgttcct gtacaaggaa gccatgaagt ccaattgcta
     8161 gggaatacga tcaatcaatt gctaagtaat gctcagcatc attatgaaca gacgatccaa
     8221 gacgaaaaga agaaacgttc gcttgaaatc caaactatgc aagcacagat acagccccat
     8281 tttatttata atacgctgac tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa
     8341 gcagttcaag gaatcgacag tttcattact ttactaagaa gtacgattgg gaaaaaagaa
     8401 gaagtgattc cagtcaagga agaaatcaaa agcgtacaaa gttacatcga tcttttgagt
     8461 atgcgatatg gcgaaagaat ctcggctaaa ataatgattc ctgatgaact gcagtcatta
     8521 tctatgccga atatgatcct tcaaccaatt atcgaaaacg cctatcttca tgcttttcac
     8581 aataaaacgc aaggattcat cacggtgtac ggcaaaacaa aaaatcagct tcttttattc
     8641 gaagtgattg ataacggcga tggcttcgat actgaaaata ccaaacaaaa aaatgatcat
     8701 ttttcaggaa tcggcatcag ccatgtagat gagcggatac gcctaatgta tggcgatgca
     8761 tatggcttaa cgatccaatc agtgattggg acaggaacga ctgtaacgat ttgtctaccg
     8821 cttcttccta aaaatcaatc agaatatcaa aaataaagaa tagccaagcg ctgatttttt
     8881 tattttaagt taaataaatc aatcagtatt cttgactttc atctacgcgt ctcttctact
     8941 gtcagcactg gataacagcc caatatttga ctttctcctc cgagcatctt gatttcttgg
     9001 agcgcattct ctactaatgt cattggacgg tccaacaaca aatcgatcac gaaaaaatat
     9061 tctcccaagc tagttttcaa tggtcgggat tcaatcttac ttaagttgat ttcccgccag
     9121 ccaaaagctg ccagcatttt atgaagcatc cctggccgat tagcaggtag tgtcaagatg
     9181 acactcattt ttactggagc tgactgctgg ctggtcatct ttcggtcacc gacgatccaa
     9241 aaacgtgtct ggttcaactc attatcttgg atattctcag ctaagatctc caatccaaca
     9301 tgctgtgctg tttctaatga agcaatcgct gctgcgtctt ctttcggatg ttctgctaca
     9361 tacattgctg cagcagttgt tgattctgtt gctactaaag gaacattagg ataatgcgtt
     9421 tctaaaaact gttgtgattg tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt
     9481 gttgctggat tgcctaaaag ctgctgcttg ataggaagaa cgatttcact tttaacttcg
     9541 acttctggat gtttggaaag aagatcgatt gtgtgatgaa cagctccttc caatgaattc
     9601 tctacaggaa cgacagccag atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg
     9661 atggaagcat acgcagtcaa ttgttctgta ggaaatagct gacaagccgc ctgataagtg
     9721 aatgaacttt ctggccctag atagctgacg ttcatatgct tttgatcctt tctataatgg
     9781 tatcgatgat cttttctggt gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt
     9841 cataccaaga aagtcgttgt gccaataatg cttttatttc ttctcttgtt tttccaagag
     9901 ctaaaggtcg aatagacgtt tcatcttgtt ggatacgatc aactagacag tccgcttctg
     9961 cctctaagta aagaacaatc ggctgtgttt ttaaaaaacg ccgattttct gcactttgga
    10021 caatccctcc accagtcgcg ataattttgt cttcatttga cagctttctt aaaatatctg
    10081 actccacttt tcgaaagctt ttttcaccgt aatagtgaaa atattcggca atcgacaatt
    10141 ggatatgttc ctcaatcttt gtatctaaat ctacatactc tttttgtaaa cattgagcta
    10201 accctttacc gattgttgtt tttccagcgc ccatgaaacc aatcagcaaa atgctagcca
    10261 tgagcttctc ctcctgacac aagttctgct aaatcgtcaa aaaatgccgg ataagagatt
    10321 gaaacagctt cagctccttc tagttcgcaa ggtccatcag ctatcaaagc agctacttgc
    10381 agcatcatac cgattcgatg atcgcctctg ctggacactt ttgcgccatg cagaggtgtc
    10441 ggcccatgga tgatcagacc gtctgctgtc gcttttatct ttgctcccat tttctgtaat
    10501 tcttctgcca ccgcatcaat tctgttggtt tcttttactt ttaattcttc tgcgtctttg
    10561 atgatcgtga ttccttctgc ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc
    10621 agacgcggaa tgatttctcc accaatcgtt gctttcttca aatgactcgt cttgacactt
    10681 aaatcagccg attggttctg ttcattgtga ttcgtctggg taatcgctgc gcccatctcc
    10741 tccaacacat ctaagatacc agttcttgtt ggattgaccc cgacattttt taacaacagt
    10801 tggctttccg gaacaagaag tcctgctgct agaaagaaag cagctgatga aatatcacct
    10861 ggaacagtta tctgttgacc agttaatttt tgcggtccgg tcactatgat cgttttatct
    10921 tccactgtga tccttccgcc aaattgacga atcatttctt ccgtatggtt acgggaacgt
    10981 tctttttcaa cgattacgga tgtgccttct gcttgtaatg ccgcaaacag caaagcagat
    11041 ttgacttgcg cactggctac aggcatattg tatcggatag gtgataaaga gcgggttcct
    11101 gtcacagtga ttggtagata ctggtcattt tcttctcctt gcaagtcagc gcccatctcg
    11161 cgtaaaggtt ccatcactcg ccccattgga cgtttagaca acgaagcatc cccgaacaga
    11221 gtagtcgtaa aaggctgtcc agccaaaata cccatcaata aacgtatggt cgtaccggag
    11281 tttcccatgt caattgattc ggttggttgg acaaatgagt ggctaccgcg accatgaatc
    11341 ttgatcacct cttcctcttc ttcgatctcg acacctaatt gttggaaggc atgtaaagta
    11401 ctcagacaat cttctgcgcg caaaaaattt tgtatagtcg tcgttccttc agcaattgct
    11461 ccaaacatga tgctgcgatg ggaaattgat ttatctgctg gtatcctaac agtccctctt
    11521 aatccatgta tttgttgtaa taattgcatt tatccagcct cctatttgat ccagcaatga
    11581 taactggtat tagacataat gattcttttt gcttgtaaca aatcctgttg gtttttaaaa
    11641 ctgatttgca gtattcctaa aatatcttcc ctggtctctt ggatcttcaa attaatcaaa
    11701 gaaactcccg cttttccgat cagtccagtt acttctgcaa taacgccagg ttcatctggc
    11761 acatcgataa ataaatcaaa aaaggcagga atcgcgcctt gcttatggac aggcaactgg
    11821 tctcgacttt cttttgcccg attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg
    11881 atccattctg ctatttgtgt catttcttgt tgccaatctg ccaatcgttc caataatatc
    11941 tgcttattgc tcaacaaaat atctgtccac atgacaggat ctgaggaagc gatcctagtg
    12001 atatctcgaa agcctcctgc tgccagttgt ttggctcgcg gatactcttg attgaattgt
    12061 tctgcctgat tgactaagcc agctgccaga atatgtggaa aatgacttag cattcctgtt
    12121 atacggtcat gttctcttgc tgtaagagtt acatattttg ctttggttcc gcaaaatagt
    12181 tcttgcagtt tttcaacatc ttttttcgtc ttttccaaag gtgtaaagat gtaataggca
    12241 ttttcaaata gtttagcatc tgctgcctgt atacctgatt tatgagaacc agccattgga
    12301 tgtccaccga caaaccgaag atttttctgc tcagcggatg tcacgacttg ctgcttcgta
    12361 ctgctgacat ccgtaatgat gacgtgatca gacaagttga ttctttcaag gacatcaaga
    12421 taagctaagg ttgtacggac gggaacggct aataagataa cgtctgcttg ttctgcacct
    12481 gtttcaaaat cacttgcaac gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt
    12541 tttgactgac tatcccaacc aactactatc agttctggat tggtctgacg aatacaaagt
    12601 gccatagaag caccaatcag tccaagcccc acgataaaaa catgttgtgc catcttattt
    12661 gccccctttt tagtaatgtt tcaagtagtc acggtactcc ttcactgcag ctttcaactc
    12721 aacaagcgaa tcacttggga attttgacaa tagctctgtc gctaccacag tggctacaac
    12781 attttccgca acgacgctag ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc
    12841 tttgtaaggt tcttttgtat cgatatcaac actttgaagt ggcttgtaca atgtaggaat
    12901 gggtttcatg accccgcgaa tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc
    12961 gcctagatta ttggtacgtc ggaaatagcc tctttcttct tcccatagga tctcatccat
    13021 cacttctgag cctggtaatg aaccagaagt gaatccgacc ccaaattcta cgcctttaaa
    13081 ggcattgata ctaaccacag cttgtgcgat tttggcatct agcttcgtgt cccattgtac
    13141 gtagcttcct aatccagctg gaacgcctcc aacgagcact tctacaattc ctccgatcgt
    13201 atctccattt ttctttgtct gatcgatcaa atcttttatt ctttgctcaa ctgctggatc
    13261 aacaactcgt acttctgacg cttcagaaat ttctttgatt tcttgaatcg agatatttcc
    13321 aggtatttct gcttggattc caccaagaca aatcacgtgt cctgctacga tgatgtcaag
    13381 ttcttccaga attttcttgg caattgcgcc gattgctaca cgcatggtcg tctctcttgc
    13441 agaggaccgt tcaagcacat tccgaagatc tcgatgatgg tatttcatac cgcctaccaa
    13501 atccgcgtgt cctggacgcg gacgtgcaac tcgccgcagt gattggtctt tttcaggcac
    13561 ttctgctaca gacatgacag ttgtccaatt tttccaatct ttattttcta ccactaaagt
    13621 gacaggtgaa ccaattgttt tgccgtgacg gatgccagac gtgatccgaa cacgatcttt
    13681 ttcgatcttc atccttcctc ctctgccgta accagcttgt ctgcgagcga gttcgtgatt
    13741 gatttcttct tctgacagag gtaatcctgc tggtagtcct tcaataatgg ctgttaattc
    13801 tggtccatgg gattctcccg cagtcatata acgcatctta cagtcctcct aagtaatctt
    13861 tgaatgtctc tgtgggaaca ggaacgattt ttgcttgccc aatcttttct agcaagatga
    13921 tattcaattg gcttcctctt gctttcttat catgggttat cgcgtggaat aattcatctg
    13981 gatgacttag atcgtacgta atcggcagat ggaatttttg aagtatcctt tctaaagcag
    14041 ctgtcgatcc agttggagac aagccgattt tttctgcatg agaagtgatg gctaccattc
    14101 caatagctac tccttctcca tgactgacta ccccatatcc tgctgtattt tcaattgcat
    14161 ggccaattgt atgaccaaaa tttaaaataa gtcgatttcc ttggtcaaag acatcttctt
    14221 ccactacttt tcgtttgatt tccaacgtag cagtaatgat tggaacagca tgttccagaa
    14281 gatctttttc gtctttcagc tcgttcagct gtttccaaag cgttgcatct gctatagctg
    14341 ctgatttgat gatttcagcg attccttctc gtaaacgacg taccggcaaa gtttttagaa
    14401 cctcaggatc aatcaataca ccagctggct ggctaaatgt tccgacaagg tttttcgctt
    14461 tgtttgtatt gactgctgtc ttcccgccaa tactagaatc tacttgtgca agtagcgtag
    14521 tcggaatttg aacgaaatgg atcccacgca tgaacgtcga ggccacgaat gctgctagat
    14581 cacccaccat tcctccacca agtgcaagta tcccatcgct gcgggtaaaa tcattatctg
    14641 ctaaaaaatc gtataactca gctgcttgtt ctaaagattt actggtctca cccgccggta
    14701 cgattgaaag gactggttca aaattagctt gtctcaattg gaacatgatt ttttctgcat
    14761 atagtggagc aacgtttgta tcagtgatca cagctacttt ttgaggtctc caaatcgttt
    14821 gaagccatga tccagcctgt tctagtgcgc ctttttcaat atgaatatcg tatttttggt
    14881 tatcaacatg tacagtaagc attcgtttca cttctttctt ttaaaaagct ggaattaatc
    14941 gagtgtctga atcttttcca ttgcttcttt catgatcgca acttctttca tcatgcgtga
    15001 gtaagtcttt tcattcaacg attggggacc gtctgaccaa gcatttgcag gatcaggatg
    15061 gatctctacg atcatgccat ctgctccgct tgccacaccc gcacgagcca ttggtggtac
    15121 aagttcccaa attcctgtac catgacttgg atcaacaatc acagggaaat gagttaattt
    15181 tttcatcaat gggacagcac ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg
    15241 aatcccacgt tcgataaaaa tgacaggaga tttgtcttcg actgcaatgt attctgcagc
    15301 attaagccat tcattgatcg taccggaaat tccacgtttc aatccaacag gtttacctgt
    15361 tttaccgaca gcagatagca gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat
    15421 atcgctgtac tcagccacca tatcgatatg cccttcatcc atcacttcag taatcacttt
    15481 cattccaaat tcatcagccg cttgacggat gtatttcaat ccttcttctt ctaaaccttg
    15541 gaaagcatat ggagaagtac gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc
    15601 ggctttggcc attcgcgcac attctctgat ttggtctaat ccttcgatag aacaaggacc
    15661 agccatcgtc acgaaactgc cgtcaccaat ttttactccg tctacatcca cgactgtatt
    15721 gccaggatgg aattctcgag aagtcaattt gtatgtgttt aaaatacgca cagcattttc
    15781 tactccttca tagcgtgtaa atgctccttc ttgtaaactt cgcgtatcac cttttagtcc
    15841 aatcactact cgttctgttc cttgatcgat tgagactttg aatccttctt tttcgatatg
    15901 atcgacgact ttttttattt gttcttccgt tgcttctttt ttcataatta ctatcattgt
    15961 ttttcccgct ttcttttgtt tacttatcta tcttggctga ttttctctac tttttcaagg
    16021 tggttttaca ttaattccta ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc
    16081 tttcctactt atgacccaga taatcaacaa aaaaagatgt ccctgtagga aattgcctct
    16141 acagtgaaca tcttcaacga gccttaaaaa gcgctgcaaa aatataaaat agccactata
    16201 gatgaatttc tctacgtggc tgtaagtcgt gtttaaaaat ctttagccat catagataca
    16261 aacctggttt gtttgtaccc acgaagtcat gaatacaaac ctatctaaaa tagctaaagt
    16321 aatacgtatt cagttttgta agttttctag atttcataaa aaatcgctcc aaactgatgt
    16381 aagaattgta cctagtatag acataaaaaa atcgactgtc aatcattttt atgaaacttt
    16441 ttttaa
//
LOCUS       DADVXM010000055        16399 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.058, whole genome shotgun sequence.
ACCESSION   DADVXM010000055 DADVXM010000000
VERSION     DADVXM010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.058"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(296..1024)
                     /locus_tag="KB927_001889"
     CDS             complement(296..1024)
                     /locus_tag="KB927_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HBB6840806.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="KB927_001890"
     CDS             complement(1002..2576)
                     /locus_tag="KB927_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6840807.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="KB927_001891"
     CDS             2805..3743
                     /locus_tag="KB927_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6840808.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="KB927_001892"
     CDS             3755..4666
                     /locus_tag="KB927_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6840809.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="KB927_001893"
     CDS             4690..6162
                     /locus_tag="KB927_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6840810.1"
                     /translation="MKKNMQKYLIGGVSVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6214..6825
                     /locus_tag="KB927_001894"
     CDS             6214..6825
                     /locus_tag="KB927_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6840811.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6855..8768
                     /locus_tag="KB927_001895"
     CDS             6855..8768
                     /locus_tag="KB927_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HBB6840812.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8896..11877
                     /locus_tag="KB927_001896"
     CDS             8896..11877
                     /locus_tag="KB927_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HBB6840813.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11874..13535
                     /locus_tag="KB927_001897"
     CDS             11874..13535
                     /locus_tag="KB927_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HBB6840814.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13575..14507
                     /locus_tag="KB927_001898"
     CDS             13575..14507
                     /locus_tag="KB927_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBB6840815.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
     gene            complement(14867..16360)
                     /gene="guaA"
                     /locus_tag="KB927_001899"
     CDS             complement(14867..16360)
                     /gene="guaA"
                     /locus_tag="KB927_001899"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBB6840816.1"
                     /translation="MITRRIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYD
                     EKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALF
                     QNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSE
                     YGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVL
                     LQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDP
                     EEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVG
                     GLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEK
                     LEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSI
                     DGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE"
BASE COUNT         5239 a         2689 c         3301 g         5170 t
ORIGIN      
        1 atttaaataa ctacatccat ctattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt acaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgtttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgacga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttta ctaaatgaaa
     6181 agaatagact aagcagttag tggggggatt caaatgaacg aaaacaaatg gaccaaagga
     6241 tttaattggg tttttcaatt gttattacta aactttactt attttatact aatttgttta
     6301 ggatttggaa ttttaggttt tttccctgct acgatagctt tgattgctgg cgttgtgaat
     6361 cgaaaaaaat atggcttgca agagtctgtg aagttcatga gtaaaatcta taagaaaaat
     6421 tttgttagat ataatctata ttgctggtca gcaactttgt tgttggccgg caatattact
     6481 acgatctggc tttgttggca gcaaagcgca ccattgtttt atttattaag tacattatta
     6541 tcggtaatta cactgttcct agtctttgca atgttgaatt gggtcgtgat caaaagtctt
     6601 gggttgtgga tgatgggaga ccgactgatt gactatttgc ttttcacagc aacgatgttg
     6661 ccaacggtag tcatgcaagg cttggtgctt ggaatttatt tccgaatatt gatgattttg
     6721 cctgtgattt ttctgtttgg cggaacagct gtaacggtaa tattgattag taaattaact
     6781 gaaagagcgt tagcaaagtt gccttgtcag atacaatcgc actaattttt tcacaaaaag
     6841 gagtatttct ttctatgaag ttaactgata aacaagtagc taatatagcc tttatccagc
     6901 aacttgagat tccattgaca caaaaagatg aagaacaaat agacttgatt tttactgaca
     6961 caaaggctaa tgtgcgacaa atcaagatta ctaaaaatga gcagcaacga atctgcttgt
     7021 cttattcaca tgaagacttg ctgtatcgag gattgtttat ctgccttcca cgttttttag
     7081 ctcaaggagg agagatgcca tacattgaag aaacctcgat cattgagacc agttattcat
     7141 tagatgcttc tcgtaatggc gtgatgaata aagagactct aaaaaaattc atttcttact
     7201 tagcgttgat ggggtacaac acattgtata tttacacaga agatacctat gaagtagaag
     7261 accttccata ttttggttac cttcgcggag cgtatacaaa agaagaagtg aatgaaattg
     7321 ttgaatttgc ttctggtttt ggcatagaag tagttccatc gatccagacc cttgctcact
     7381 tgacccaatt tttgaagtgg tatgctcaac aagaactgat ggatgatcaa aatactctac
     7441 tgatcggtga agaaaaggtt tatgcggcaa tcgaaaagat gattattgcc tgcaaagaaa
     7501 tgtatcagac agagcgtatt catttgggaa tggatgaagc ctatcaagca ggtctgggac
     7561 gatatttaag cctgtatggg tattgtgatc ggacaacttt aatgattcaa catatggacc
     7621 gtgtgttatc aattgttgat aaatataaga tgaaaccaat gatttggagt gatttcattt
     7681 ataagctatt agatgaaacc ggtaaagata ggtattacaa tcctgatttt aaactcaaag
     7741 cattagcagc taaaggatta ccagcaggat taacctatgt tcattgggac tatggttcag
     7801 atgaagtttc ctcctatgag aaagtaattg ataaccattt gaaattttgt gacattgatc
     7861 attacgtttt agctagtggt gcccatatct gggggagact agccccgaat catgggaaaa
     7921 cagaagcaat tgtttctgca gctgtaaaag cttctaaaaa taaaggtgta cgttctgtga
     7981 tgttaactac ttggggagat gaagggcagg aaacagagca ttggcattcc ttaattgggg
     8041 cattaaaatt agcagattat gtctattctg aagaagagtg gaatgatttt gaggaaatct
     8101 acgatcgttt attaggaaca ggtagttatc aattaatgtc cgaattacga tatttcgatg
     8161 aagtggatac cattacaaat aacaacttac aaatggcttc cgtgagtaaa ctgctacttt
     8221 ggcaagatcc gttagttggt atatatgact ttcatgtagc cgctcataac aaaattgcca
     8281 ctagaacaat tggtacttat tatcatgagt tagctcagaa attagatatg aataaaaatt
     8341 ggaatccaaa acaaccaatt ttaacaacta ttcgtcaacg atatatactt ttagctgaaa
     8401 ttttagcaca aaaggcagaa ctaggcatct atttacaaca ctgctgtctg gtagaagacc
     8461 ttgcaggatt aatggaatta gcgaatcggt gtgaagcact agccaatcga gtaaatgaat
     8521 tggcatctat tcatgaaata atttggtatc aaacatacaa aacctatggt tgggaagtat
     8581 tagaacaacg atatgctgca ttagctcatc gtctgaaaac cgttgcgcgt cgtattaaaa
     8641 atcatcttca ggggcaagat gccctagagg agcttttgga agaacgatta ccgttttgtc
     8701 aatatcaagt gccgcttgaa atttctggct ttaattatcg gcaaagctcg gtgtcaggct
     8761 acaattaacg aaggaatctt cccgttgaac ggaccacttg ctcatctaat gggaaagtgg
     8821 ttcgttttct attcataagt agcttaccac taactctttt attaagaaga gaaaaaaagt
     8881 aggaagtgag aaaatatgtt atcggactat tatcaaaatc tgtcagttat aagtgtcaat
     8941 acagaaccat tacgtaatta ttatattcct tatgcaagta aagaagaagc aaaacaagag
     9001 ttagaaaggg aaaaaacgag ccagtttatc gatctcaatg gtacatggga ttttcagtat
     9061 tatccttctg tccaacagtt accggaaaat ttttttcaag aggcctttac tgaaagttat
     9121 gatagaattt ctgttcctgg agtttggcaa acagagggat ttgacttacc tcagtatatc
     9181 aatgtatctt atccaattcc ttttgatccg ccttatgtac ctaatgatac cccttgtggt
     9241 gtatatcggc gtcagtttca aattgagcaa acagatgcac gcttttactt aaatctagaa
     9301 ggagcagata gtaattgttt tgtttggata aatagaaact ttgtaggcta tgaccaagtg
     9361 agtcatagta catctgaatt tgatgtgacc aagtatttac aggttggggt taatgaaatt
     9421 caaattctag tgatgaagtg gtgtgatggt acctactttg aagatcagga taagtggcga
     9481 atgagcggtc tatttcgtcc agtgtatctt cttcaacgac caactatgca tctgacaagt
     9541 tatcaactac ggacgttgac tgatcctaaa aaaggaagcg gaacattaat ggtttctttt
     9601 caacgattta ctcctattga agtatcgtta cctatttctt acgaattatt ccatcctgat
     9661 ggacgtctca tagcgaaagg ggagtgttac tcggaacaac aaataaattt ggatgttgaa
     9721 gattgccttt tttggacagc agaaacgcct aaattatata cattactttt aacatgtaat
     9781 ggtgaatatt ttaaagaaaa agttggcttt cgagcactga cgatcaagaa tcgtaagtta
     9841 ttgctgaacg gaacacctat taaattatat ggagtcaact atcatgacgt gaatcagcaa
     9901 ggcacgccag tgatgacccg agagcagtta cgtgcagatt tgttattaat gaaaaaatta
     9961 aatgtgaata ctgtacgaac ggcacattac cctaaatcac cagattttta tgaattggcg
    10021 gatgagattg gtctgtatgt aatcaatgaa gcagatttgg agtgtcatgg tgtggttaat
    10081 ctatatgata ctgaagcgaa ttatcaacta attgctaatg atccgacatt cgaaaagccg
    10141 attatggacc gagtgatccg ttctattctt ccttatcaaa atcgaagctc tatcattatg
    10201 tggtctatgg ggaatgaatc tggttatgga gtaaattttg aaaaagctca agctttagca
    10261 cggaaattgg atgattcacg gttgattcat aatgaacgct cgattgaacc agttattgac
    10321 caagtgaatg attttagtaa cttggatgtt attagtcaaa tgtatccccc actggaagat
    10381 gttcatcgtc attgtcaaag aagtgatact gaaaaacctt tttttatgtg tgaatatagc
    10441 cacgctatgg gcaacggtcc tggagatctt aaaacgtact tcgatttgat tcaacagtat
    10501 gattcctttc ttggcggttg tgtctgggag tggactgatc atgcaatcaa tagaggaact
    10561 ttagaaacgc catcttattt atacggtggt gattttggtg aaaaatatca cgacggcaat
    10621 ttttgcgtag atggtttatt gaccccagat cggcaattaa cagtaggtgc attggagtac
    10681 cgtaatattc attcgcctat tcaactgatt gctgtagatg aggagctgca agaagtaacc
    10741 ttgagcaata taactgcttt tacagccggt tcagcattta acctttctct tgaatggtat
    10801 atagatggaa aaaaaacagt ttatgaagta atgaatcctt tcatacttga gcctggcaaa
    10861 agttgttcat tgcccatcac agtacctaca acgattcatg gtgctcatac ggttgctgtt
    10921 tcgctatctg tttataaaaa tgatgagctt tatggacagc aacagctctt tcttaaaaaa
    10981 gaaaaaatga gattgccaag aactgctcat cataatgatg caccacaaat ttcagtaaaa
    11041 ggcacagagc tgataatcaa aggagaatcc tttatttata tatatcaatt agcaaaagct
    11101 gcgttcactt ctgtaaagat caatcaaaag gaacttttgg aacgtcctac tcaattttca
    11161 atttggcgtg caccaacgga taatgatcgt aacttagtaa acaaatggaa agcagctgga
    11221 tatgctgaaa tgtctttaga aatcagaaaa aaagactgga aattcgtaga tgatcatctc
    11281 ctgatcgaaa cgtcttatcg aggagttatt ccaggattac agccaatttt tacaatgcac
    11341 atacagttga aaataaatgg tgcaggcgta atcaaccaaa aagtatcagt ggagaaaaat
    11401 ccgatttttc cagatttccc tcgctttggg atggactggc cgttgaatga tactttttcg
    11461 aaggtttctt attgtggcta tgggccgtat gaaagttatc ctgataagca ctatgctgcg
    11521 atgtttggta tttatgagat ggagattgag gaatttgatc agccatatat caaaccacaa
    11581 gaatatggta accgctggca atgtgattgg gtatcaatca aaaatcatca aggatctacc
    11641 atgacggttt atggaaactc taatttttct gctctgcctt atagtcaagc tcaattaacc
    11701 gaaaagtcac accattatga attaataaaa gaaaatagaa cttggttcaa tttaagttat
    11761 aaacaaaatg gtatcggctc acacagttgc ggtccttatt tagaagatcg tttccgtttt
    11821 atggaagata cttttgactg gaatatagtg attactttca aaggagaaaa tagatgaaag
    11881 aaacaaagat caatcaagtc aaaaaaaaat tatctcgtta tcaagaagtt gtttatcgaa
    11941 accattgctt aaaatggtca aaaaataagc tgaatgttcg ttttaatgga ttattttatc
    12001 gtttcgaaca gttagaagaa gtctggaaac cggtaacgaa tttccaatca tgtcctgtac
    12061 agctcataaa tgatccaaaa gaaacatacg atttatgtat aacacacctt tataaccagc
    12121 atttgaaaaa tgacggattt tatttaaagg ttactaatga caatcaactt acgattgaat
    12181 cagcaaacct tcgagggttt caatatgcta tggaagcctt attagagagt tttttttcgg
    12241 taggagatca attattatta ccggaattga ttctgaaaca tgaaccatca gtgaaaattc
    12301 gaggaatcat tgaagggttt tatggtatcc cctggacaca tgaaatgcgc ctctctcttt
    12361 tttcatatat gaaagataac caattgaata cttttatgta tgcccctaaa gatgatgaat
    12421 tattacgtaa aaaatggcgt gaactctacg atgcgcaaga attagacaaa tttaaggagc
    12481 ttttatctgc tgctgaggct agcaatatcg atttttggta cttaattagt cctggaaatg
    12541 atattgatat tacgtgtgaa gaagacattc aagttcttct gaaaaagtta gaacaactga
    12601 ttgagcttgg cgtatttcaa tttggtctat taatggatga tattgactat caattaaaag
    12661 gtgctgctaa acgccgtttt cgagagccag cattcgctca tgcctattta gtgaatcgag
    12721 tagaggaata tcttagcact cggttgtcca atcatgaatt agtcatttgt cctacagaat
    12781 atgataatcg tcatggttct cgctatttag caacgttaag tcaagaaata ccagaacaat
    12841 taccgttctt ttggactggc ccaagcacgt tagcggcgtc aatttctaca gaagagctgc
    12901 aggaaatggc ttctgtctat caacggccga tgctgatttg ggataatatt ccggtaaatg
    12961 attatttaga ggataaagaa ctattgttca tgagtccata tgagaatcga acaccgaatc
    13021 tttctaagga gagataccag gttacaggag tagtttcgaa tccaatggct caattagaag
    13081 cttcaaagtt tacgatcaat agtatggcta attacttatg gaactgtgag cgctttgatc
    13141 ctttggaaac ttggacgtca gtcgttgaaa aagtagttgg aagtaaacta caaccagctt
    13201 atcttacctt aaccaatgct tttccaaatc attacacaag cagtctgctt tcagatgaag
    13261 aattactgct agccaaagac ccagaatggg tcacaaaaga aatggctgct ttagtccaag
    13321 cagtaaaatg gatccagcaa gaacaacata catctagatt gagaacagaa ttggagcctt
    13381 ggttacaagc aatcacagaa agttggactt tctggcaaga atggcaatta aaaaaagatc
    13441 caaaagaagc agaagaatgg ttggctaaga aaaaaacaca ccgcatagga cgtgatttag
    13501 taactgccca tttagagcaa attatcaaaa gttagatatc ttaaaaaata aaaagcaaga
    13561 aaaaggagaa caaaatggtc aagagattaa ttagtgcaaa ctacagtgat gtcaagaaaa
    13621 tgacgtcaaa agagttgaag caatccatca aagcgagtga aggacgggtg attgtttgtg
    13681 aaacggttgc taatactctt ccacaatctg gagaaattac gaatgcagaa gttgcgtcag
    13741 catttggtgc agatttgatt cttttaaatg gtttcgattg ttatcgtcct gcagtttttg
    13801 gactaccaaa tgtgacgatt gagaaggttt ttgatctaca gcaaacgatt gaaaacccga
    13861 ttcctaaatt aaaagaacta gtcggtcgtc ctgtgggaat taatttagaa cccattgccc
    13921 ctaaaacaaa tatgatgagt gagaaagtag aaatcagcca aggaagagca agctctgttg
    13981 aaacgataca aaaagcagaa gaactaggag tcgattttat ttgctttacc ggtaatccag
    14041 gcactggagt aaccaattta gaaattacta aatccgtaaa aatggcaaaa aagtattttt
    14101 cgggattgat tattgctggg aaaatgcata gcgccggctc agaagagcca gttgtgaata
    14161 aagaggcgat tatttcttat gcggaagcag gcgcagatat tttactagtt ccttcagtag
    14221 ggtctatccc aggcttttta gagcaagacc taattgaagc ggttcggttg gcaaaaaaat
    14281 atgatttgtt aacgatgtct gcaatcggta ctagtcagga aagtgcccga ccagaaacat
    14341 tgcggcaatt agccattatg aataaaagtt gtggtgttga tttacaacat attggagatg
    14401 ctggatacgg gggattggca ccagcagaaa atattttcga aacctcggtt gcaattagag
    14461 gaatgcgaca taccatcaac tgcgttagcc gctcgatcaa tcgctaacaa aattaaataa
    14521 aaaatggtta aattgattat ttaagtggga acatacttga gatatcagct aacttctgtc
    14581 attttaaaaa aagggactgt gacagaagtg aaaatagaca aaaaatatcc gaacaagaga
    14641 ctaggatagc agaaaaacta tcgttttgca acgaggacca actggaacgt aggagcaatt
    14701 ctcttattgt tcggatattt cgcttgttca aggacttatg tctgtagtgc ccttttttgg
    14761 taggaaaaat ggtagggaac catatcattt ttaatgaaaa tcaagcattt caaaagttga
    14821 aaaacgttga tttatcggca ttccccatcc atattatatt tacgtcttat tcccactcca
    14881 ctgttgcagg tggtttgctg gtaatatcat acacgatacg gttaacgtgt gcgacttcat
    14941 ttacgatacg gacactgatt ttttgcaaga cttcccaagg gatacgggca aagtcagcgg
    15001 tcatgccgtc aatagaagtg acagcacgga tacctacagt gtagtcatac gtacggccat
    15061 ctcccataac cccaacagag cgaatgcctg gtaggacggt gaagtattgc cagatgtcgc
    15121 gatctaaacc ggcattggcg atttcttcgc gcaagatagc gtctgattca cggacgattt
    15181 ctaatttttc ttctgtcaat tcaccaagga cacgaatacc taagcctggt ccagggaatg
    15241 gttggcgcca aacgatgctg tcaggcatgc ctaattgggt acctaattca cgtacttcgt
    15301 ctttgaacaa tgtgttcaat ggctcgatca gcttgaattg catgtcttca ggtaatccac
    15361 ctacattgtg atgtgatttg atggtttggg cagtttcagt tcctgattcg atcacatcgg
    15421 tataaagggt tccttgtgca aggaaagaaa cgccttcttc accggcaagt ttggttgctt
    15481 catcatcgaa gacatataca aattcatttc caatgatttt acgtttttct tctggatcag
    15541 acacgccagc aagttttgat aagaaacgtt ctttggcatc gacttttata atgttcaagc
    15601 caaattttcc gccaagactt tccataactt gttctgcttc acctttacgc aacaatacgt
    15661 gatcaacgaa gatacatgtt aattgatcgc cgatcgcttt ttgtaaaaga acaccaacaa
    15721 cagaggaatc tactccgcct gaaaggccta ataaaacttt tttgtcaccg acttgttcac
    15781 gaatttttgc gatctccatg tcgatgaagt tatccattgt ccagtcacca gtacattggc
    15841 agacatctag tgtaaaatgg cgcaacaagt catttccata ttcggaatgg cgaacttctg
    15901 catggaattg gattccgtac attttgcgtt ctgcattttg gatcgatgcg atggggcaat
    15961 ctttgctggt agcaacgaca tcgaaatcag tcggtgcttg ggtaactagg tcaccatgac
    16021 tcatccaaac ggtttgtttt tcaggagtgt tttggaaaag ggccgcttct gcagaagtga
    16081 tttccaattc tgcttttccg tattcacggt ttttggctgg tttaactttt ccgcctaatt
    16141 tataagtaat caactgcata ccgtaacaga ttcctaaaac tgggatcccc aaatcaaaaa
    16201 tcttttcatc aataccaaag gccttctcat cataaacact gtttggtccg ccagaaagga
    16261 tgattccttt agggttcatt gcctttactt cttctgcggt aatgcggtgg ctcatcaact
    16321 ctgagaaaac accgaactca cgaatacggc gagtgatcag ttggttatac tgactaccgt
    16381 aatcaagtac gataatttt
//
LOCUS       DADVXM010000056        16342 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.059, whole genome shotgun sequence.
ACCESSION   DADVXM010000056 DADVXM010000000
VERSION     DADVXM010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.059"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(290..2017)
                     /locus_tag="KB927_001900"
     CDS             complement(290..2017)
                     /locus_tag="KB927_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBB6840817.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2010..3203)
                     /locus_tag="KB927_001901"
     CDS             complement(2010..3203)
                     /locus_tag="KB927_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6840818.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3390..4034)
                     /locus_tag="KB927_001902"
     CDS             complement(3390..4034)
                     /locus_tag="KB927_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6840819.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4128..4262)
                     /locus_tag="KB927_001903"
     CDS             complement(4128..4262)
                     /locus_tag="KB927_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBB6840820.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4264..6396)
                     /gene="feoB"
                     /locus_tag="KB927_001904"
     CDS             complement(4264..6396)
                     /gene="feoB"
                     /locus_tag="KB927_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBB6840821.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6393..6866)
                     /locus_tag="KB927_001905"
     CDS             complement(6393..6866)
                     /locus_tag="KB927_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBB6840822.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7267..7491
                     /gene="nrdH"
                     /locus_tag="KB927_001906"
     CDS             7267..7491
                     /gene="nrdH"
                     /locus_tag="KB927_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBB6840823.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            7650..9809
                     /gene="nrdE"
                     /locus_tag="KB927_001907"
     CDS             7650..9809
                     /gene="nrdE"
                     /locus_tag="KB927_001907"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBB6840824.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            9859..10824
                     /gene="nrdF"
                     /locus_tag="KB927_001908"
     CDS             9859..10824
                     /gene="nrdF"
                     /locus_tag="KB927_001908"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBB6840825.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(10913..12052)
                     /locus_tag="KB927_001909"
     CDS             complement(10913..12052)
                     /locus_tag="KB927_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6840826.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12361..13074)
                     /locus_tag="KB927_001910"
     CDS             complement(12361..13074)
                     /locus_tag="KB927_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBB6840827.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13328..14029)
                     /gene="nagB"
                     /locus_tag="KB927_001911"
     CDS             complement(13328..14029)
                     /gene="nagB"
                     /locus_tag="KB927_001911"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBB6840828.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14263..15795
                     /locus_tag="KB927_001912"
     CDS             14263..15795
                     /locus_tag="KB927_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6840829.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(15986..16165)
                     /locus_tag="KB927_001913"
                     /pseudo
     CDS             complement(15986..16165)
                     /locus_tag="KB927_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(16185..>16342)
                     /locus_tag="KB927_001914"
     CDS             complement(16185..>16342)
                     /locus_tag="KB927_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBB6840830.1"
                     /translation="SSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGT
                     LRYSLGY"
BASE COUNT         5064 a         3375 c         2857 g         5046 t
ORIGIN      
        1 agaatttaat cacttttaag tatataaact atgtatattc tttaatattt tttgagaatg
       61 cacttcgtac ataataaact ttaatcacat tagtctttca tacctacgat cgatctcttt
      121 gactcgcacc cataaattca taatagtttg tcggcgtctt tgaacgtttc gaagatgagc
      181 tacgcattct ctttttttat agacaaaaaa gatagagacg aacatggagc ttccaaattt
      241 ggatatttga tccaattttg gaagctccat ttatttcgtg tctgtctttt tattttttcc
      301 agctttcgac taattcttgg ttctctttga tccagtcttt tgctgcttgc tgtggatctt
      361 ttccattgtt gatttccaac ataacttttt ccatatcttt ttctgaccaa tggaaattgt
      421 ctaatacttt gtaagcttct ggctggtctt ctttcaatcc ttttcgaacc atcgtatgga
      481 tctgctcttc gcttcccatt ccgttttcag gatcttctaa gtatttcaga tcatatttgg
      541 caaacatcca atgaggtgtc catcctgtaa ctacaattgg ttcgtgtttt ttgatcgctt
      601 gacctagtgc aacggtcatt gctcctgaag aagatgtctc tactttccag tctttcaagt
      661 tgtcatattt ttggatcgtg ttttcagcag ccgtaactac accagctcct ggctcgattc
      721 ctatgatttt cttacctgcc tgatcggtta actcatcgat cgaatttaca tccatgtagg
      781 ctggcactgc taaaccaact tttgctcctg tcaaattggc acctaggtct tcgacttgat
      841 ctttatattg tgcatattgt gaaccatgag ttttaggtag ccaagctgaa accatggcat
      901 ctgactcgcc atttgaaaca gatttccaca tgattgaatt atctaatggc gtcatcgtta
      961 catcatagcc catttgtttc aatacttcac cgactacatt tgttgaagca acttctgtat
     1021 cccattcaac ataagataag ttgatacgtt ttgtttcttt ggcagatgaa aaactcccta
     1081 taccaatcgc acctaagatc actactacta cagcaccaat gatcagtcct tgacgttttt
     1141 tacttttctg tgttgttgct cctgcagctt ttttattgtt tggctggttc aaatgctgtg
     1201 taaaacggtc aatgatgatt gctaagataa ctaatgcaac cccgttgaca aatccattcc
     1261 cgacttgtgc tctttgcaat gctgataata cgccgcgtcc taagccgggt gcaccgatca
     1321 tagaggcaat aacgaccatt gaaagtgaca gcattgttgt ttgattgatc cctgccatga
     1381 tcgtactttt agctaaaggc aattctagtt tgaatagttt ttgacgactt gtgctcccga
     1441 atgaatcaga agcttctact aattctttag gaacttgtcg aatccctaaa ttcgtaaaac
     1501 gaacggttgg tggcagagca aagatgactg aggcaaatac ccctggaacc atcccgatac
     1561 cgaaaaatgc aactgctgga atcaaataaa cgaatcctgg cattgtctgc ataaagtcaa
     1621 ggatcggttt gataatactt tgggctttac tgctttttgc catcaagatc cctaatggta
     1681 ccccaatgat gatcgagatc acactagata aaagaacaag tgtgacagta ttcatcaaat
     1741 cattccatag accttggtta taaataaacc atagaccgat taatgtgaac aacgtaagtc
     1801 ctggacgttt cttagaaata aagaaagctg ctaccgtcaa taacaagata aacaaaggag
     1861 ctggaatcac taacagtaaa tttgtaatcc ccgacatcac tgcctgtcca atcgtttgta
     1921 aaaatgaaaa taggccagaa aaagttgtcg taaaccattc tgtgatattt tctacccagt
     1981 ttgccactgg taattgatag ttcaatagat tattcatgtt cactcacctc gcttgtttct
     2041 gctaatgctt caatcacact acctcggatg acgacacctt ttaattttcc atcctctaca
     2101 actgcaagtg gagtcggtga gtcataaata atattgaaaa tatcacttac caccatgtct
     2161 ttcccaatca ccgtcacatt ttcatctagg aagtcgatca atggacgttt ttgcttccta
     2221 gcttctaacg cttgatctgc agtgatgatc cctttcaggt gtctctttct gtcaacagcc
     2281 atcagcatgc tgacttcttc attacgcatc cttgtcaatg caacgtttgg tccatcagat
     2341 tcgatattcg tcgtcaatgc aggtaccatg atgttttgag ccgtaagcac tttggaacga
     2401 tcgacttctt ccacaaattc acgtacataa tcatttgctg gattggtcaa tatttcttca
     2461 cctgttccga tctgcatgat ttcgccgtct ttcatcaagg cgattctgtc cccaatccgt
     2521 aaagcttcat tcaaatcatg ggtaatgaaa ataatcgttt tttgaacatt ggcttgcagg
     2581 tccagtaatt cgtcttgcat ttctcgccgg atcagcggat caagagccga gaacgcttcg
     2641 tccatcagca agatctcagg atcatttgct aaagctctgg ctaggccaac ccgttgttgc
     2701 atcccaccag ataactgact aggatattgg tctttaaatg aaagcaaact agaattttct
     2761 aatgcttttt ctgctttttc ttgtcgttct tctttaggta caccacggac ttctaacccg
     2821 tattctgtat tttccaagat cgttcgatgt ggaaacagac cgaagttttg gaaaaccata
     2881 ttgattttat gacgacggac ttctcgcaat tcttctttgc ttaacttcga tacatcttct
     2941 ccatcaatat agatactgcc cgaagttggc tcaatcagac gattcaatag acggatcaat
     3001 gtggatttcc cactcccgga aagccccatg atcacgaaga tttctccttc ttttacgtca
     3061 aaattcacgt catacacacc aaccgttgca ccggttttct ttaaaatctc cgttttcggc
     3121 tggtgatcat tcatcatatc taaagcggct tgtgtctttt taccaaatat ctttgttaaa
     3181 tgttttactt ctacttttac caaacaaatt ctcctttttt atgtaaattc atttttcttt
     3241 ctgaaaaaag tgaccacact atgttaacat catgtagtca ctttgtcaaa aatgaaagaa
     3301 atttgcttgt ccaaactgaa aaaaacttgg ctaaatcttt gtaaataaaa ggtttagcca
     3361 agttaatatt tttttaatat ttcacacaat cattctgcaa gctgatgctc cgggtaaaaa
     3421 aagtttgtca tacgctgtag tgtatattca tttccaataa aatgaacgat gtcccctgcc
     3481 gtaaatttag cataggggcc aggtgaaaca agcagttctt cattatgaga aattgcgata
     3541 actgtggcgc cagtcgcctg ccagatattc aactcgctaa ttgaacggtc cagatgcatt
     3601 gctttttctg ataaagataa ttcaaacgga agtaaaggat tcatcttatg tattcgcttc
     3661 gtttgattga ccagctgatc caataattga gaaaaatgat tcagctcatc ttgttgcttc
     3721 tccacacttg ccatgatttc tgcttttgta tcttggatgg attgtacatc ttgatattgc
     3781 aataggaaat cttttgcttt ttccttcgaa gcaacaaatg ccccacttcc atgccgtact
     3841 tccatgattc caagatctac cagcacattg atagccttgc gggtagtctc aggagaagca
     3901 ttgtacgtac tggcaagtgt tgagcgggca tggatcttct cacccacttt atatcggttt
     3961 tcaacgatac gttcggctaa atcaacagca atctgctggt agcgcgggcg gacgattttt
     4021 ttctttccag acattttctt tcctctttct ttttttactt tccctcatct tactatgctc
     4081 tagcaaaata agcaaaaaag gggagaatag cctcttgcaa cgactgatca tcgcttgatc
     4141 tgttcctttt ttactgggca agctgtttga cagtcatcac aattcttacc ggattttaaa
     4201 cgagtataga caattgcgcc tgcacttcca aagattaaca cacttaataa gaatgtcgcc
     4261 atcctattcc tctccttcta atgacaatat agtataaaac tggttcttgg attttggctg
     4321 acggaacaaa acataaacga gtcctatcat cagtaaaata gcaagatacg tccctaacgc
     4381 tacctgtcca ccctccaata agtgtcccaa ctgataaatc acaaaactaa ctaaataagc
     4441 taaaccgcat tgatagccta tggcgatcca agtccatttc ttggcattca tttcccgatg
     4501 gatagcccca attgccgcaa aacaaggcgc acaaagtaaa ttgaaggcta acaatgaata
     4561 agctgctgcg ggagtatatg tgtgttgtag cacttgccag atttctctgc cattttcgga
     4621 tacttccgca tgaccaaaca aaataccaaa tgtgccaata atattttctt tagcgaccaa
     4681 tcctgtaatc gctgcgactg ttccttgcca gtttccccaa ccaagcggct gaaaaacaac
     4741 tgccaggatt cgcccgaaaa aggctaagat actttggtct tcagaaacag gttgagcata
     4801 aaaattataa gaagagctga accagatcac gatactagaa acaaagataa tcgttcctgc
     4861 ttttttaaca aaagacttgc tgcggtcata ggtttgtctt aggaccgctg accattgagg
     4921 aaaatgatat gcgggcaatt ccatgataaa aggagctgta tctccagcaa acaaacgtgt
     4981 ttttttcaag ctgattccag agaaaataat tgcagtcata ccaagaaaat aggcagaagg
     5041 agctacccaa gattgatgag gaaaaaaggc ccctgctact aaggcaataa tcggcaactt
     5101 tgcagaacaa ggcatgaagg ttgtgaccat gatcgtcaaa cgacgatctt gctcgttttc
     5161 aatcgtgcga ctggccatga cgcctggcac tccacatcct gtagcaatca gcataggaat
     5221 gaaggatttt cctgaaagac cgaatttcct gaaaagtcga tccatgacaa aagcgatcct
     5281 cgccatatat ccgcagtctt ccagaaagct caagcataaa aacaatataa tcaattgcgg
     5341 tagaaatcct aacactgctc ccacgcctgc gatgatgccg ttcaagatca gctcctgcat
     5401 ccatcccgct acttgccatt cagctaacaa tctgccaaca tgttctggta accatgtacc
     5461 aaacaatgtg tcattgatcc aatctgtccc cattgttcct actgtttgaa tagccagata
     5521 atagatcagc cacatcacaa atgcgaagat cggcaaggct aaccaacgat tcgttgcaat
     5581 ctgatcgatt ttgtcactca tcgataattg gaaagaatca tttgacacaa cacagagtgt
     5641 acatagttgg gtaataaatt cataacgttc attgaccaga atcgtctcac tatcgtcgtc
     5701 caatagtttc tctgttaact ggatcagttg ctcgatctct ttttgctgag aaactgctat
     5761 ctcgtaatcc tctcttacct tctgatctcg ttcaaaatat ttcattgcat accagcgttt
     5821 cttgccgctt tgttctccta gtacatcttc aatttcatgt aaagctgctt ctaaacgtgg
     5881 atcatatgta cagggaacag gaatagaagg ccgctttttt gcagactcct gaatcttttc
     5941 gattagtttt tcgattcctt gctttttcaa tacgctgatt ggtaaaactg gtacaccaag
     6001 accataggaa agcttttcta gattgatttt ttttccttct tttttgatga catccatcat
     6061 attcagacca atgatcatag gaatgtctaa atccaataac tgcgtagtta aataaagatt
     6121 tcgttctaaa ttggtagcat caataatgtt gatgatcagt tcaggctgtt cctgaaccaa
     6181 ataatctctt gcaatcactt cttctggtgt ataaggagac aaagaataga tgccgggtag
     6241 gtcctgaata tgaatgttcg gatttttttt caacgatcct tctttttttt ctactgttac
     6301 gcccggccaa ttccctacat attgattcga accagtcaag agattgaaca agctagtttt
     6361 cccgctgttt ggatttccga ctaacgcgat attcattctt tttcctccct ttgtatcaag
     6421 attagttcgg cctctgactt tcgtaacgtc agttcatacc ctcgcactgt cagttcgatt
     6481 ggatctccca gaggggctag ttttcggata actattttta catttcgcgt caatcccata
     6541 tccattaacc gtcgcttcac tgcgccttgt ccgtggattg ctacgacgat cccagtctct
     6601 cctgctttta attgatcaag agaagtccag ctttcagagg aagcagtctt tttattgaca
     6661 aagatttgac ctagtatttc ccgacttact gccactcgat gactttttac cagtaaaatg
     6721 gcattgttgc ctgataaatt gacgacgacg attttacttc cggcaacgat cccgatattt
     6781 tgcaaatggc gttttgtttt ttcttctgtt tcgattcgtt cgacttgata aacgaaattc
     6841 tgctttgcct gcgctaaggt ctgcatattg attcctctct tgtgaaataa atcatgtatt
     6901 aaaatcattc attatatgtt ctaattttct tacgtgttac gcaaataaat gagaatcatt
     6961 ctcacataga atactctcgg taattgagaa tgtcaattat acttgtgata ttatgagcga
     7021 atctttagta ttgatagata aaaatgagaa aaaaatattt cttcatagtt ttccacaatt
     7081 ttttctctat taaatttgct attttcccac acgatacttg ttttcagctc ttttttcaaa
     7141 aacacaaaac ttagtattcc acagtttcca caacacaata tgtagtgttt gttgtttgac
     7201 ttttttacta agagttttat actatctatt atagataata agaatgtgtt agaggaggca
     7261 ctcaccatga acgtaaaaat cttttctaaa aataattgta tgcaatgtaa gatggtcaaa
     7321 cggtttttaa cagaaaatca aattgctttt gaagaagtca atatcgatga acagcctgaa
     7381 gcagtagact ggttgaaagc acaaggattc caaagtgttc ctgtcattac ttctgatgca
     7441 gaaacagtta tcggattccg tcctgatcag ttgcgtaaac ttgccagcta acatgactaa
     7501 aagaatcaaa acgtgataca tggatttgaa gggcttgaga cagcaccagt ttttgtcgca
     7561 aacttccaaa tcctttttta aagcttaaaa acaatgcaat gatttgcaat caagcatcat
     7621 caaatacgaa atgaaggttg ggcgtacgta tgagtcttaa aaatttacaa gatgtcagtt
     7681 atttcaagct gaataatgaa atcaatcggc cagtcaatgg tcaaatccct ttgaataagg
     7741 ataaagaagc tttagttgcc ttttttgagg aaaatgtcaa accaaatacg atgacttttc
     7801 catctattat ggaaaaaatc aattacttga tcgatcaaga atatatagaa gcagaattca
     7861 ttcaattgta ttcaccatca tttattgaaa agctatatca atttttggac gagcaacatt
     7921 tttctttcaa atcttttatg gctgcttaca aattttattc tcaatatgcg ttgaaaacca
     7981 acgacggttc cgcttatctg gaaacttatg aagatcgagt agccttcaat gcgctttact
     8041 ttgcgaacgg ggatgaagaa ttagcacttg ctcttgcaga cgaaatgatc catcaacgat
     8101 atcagccagc tacaccttct ttcttgaatg ctggacgtaa acgtcggggc gaattggtgt
     8161 cttgtttctt gactcaagtc actgacgata tgaactctat cgggcgctca atcaactctg
     8221 ctttgcaatt gtcccgtatt ggtggcggcg tagggattac tttatcaaat cttcgtgaag
     8281 ccggcgctcc tatcaaagga tatgagggtg ctgcaagtgg tgtcgttcca gtcatgaaat
     8341 tattcgaaga tagtttcagc tattctaatc aattaggtca gcgtcaagga gctggcgtgg
     8401 tttatttgaa cgttttccat ccagacatta ttgctttcct ttcagcaaaa aaagaaaatg
     8461 cagatgaaaa gattcgcgta aaaactcttt ctcttggcgt gatcgtacct gataaatttt
     8521 atgaattgac acgtaaaaac gaagatatgt atttatttag tccatatagt gtcgaaaaag
     8581 aatatggtgt cccattctct tatgtaaata ttacagctga gtatgatcat ctagttgcaa
     8641 atccaaacat tcgcaaacaa aaaatcaaag cgcgtgatct tgaaaatgaa atctcaaaat
     8701 tacaacaaga atctggctat ccttacgtaa tcaatattga tacagcgaac cgcgagaatc
     8761 caatcgatgg caagatcatc atgagtaatt tatgttcaga gattttacaa gttcaaacgc
     8821 cttctgtgat taacggcaaa caggaatatg aagtattagg aacagatatc tcatgtaact
     8881 taggctcgac aaatatcgtg aatttgatgc aaagccctaa ctttggtcaa tctgtgcgta
     8941 cgatgactcg tgcattgaca tttattacag atgcatctga tatcgatgtc gtaccaccga
     9001 tccaaaacgg aaataagctg aatcatacga ttggattagg tgccatgggc ttacacactt
     9061 atcttgcaaa agaacaaatg gaatatggct cagaggattc attagacttt acaaatattt
     9121 acttcatgct gttgaattat tggacacttg ttgaaagcaa caatatcgct cgtgaaagaa
     9181 aacaagtttt ccataatttt gaaaaatcag cttatgctga cggcacttat ttcgaaaaat
     9241 acgtaactgg agaattccag ccaaaatcag aaaaagtcaa agcattgttt gaaggcattt
     9301 ttatcccaac tgctgaagat tggaatgctt tgaaacaagc agtaatgaaa gatggactgt
     9361 atcatcaaaa tcgcttggca gtagcaccaa atggctcaat ttcatatatc aacgatacga
     9421 gtgcaagtat tcatcctatc actcgcatga tcgaagaacg ccaagagaag aaaatcggta
     9481 aaatttatta cccagcgcct tatctatcca atgagacgat tccgtattac acttctgctt
     9541 atgatatgga catgcgtaaa gtaatcgatg tttatgcaac ggcacaacaa cacgtcgatc
     9601 aaggcatgag tttgacttta ttcatgcgtt ctgaaatccc agaaggcatt tatgaatgga
     9661 agacaacaac gaagcaaacg acacgtgatt tgaatatttt aagacattac gctttccaca
     9721 aaggaatcaa atccatttat tacgtacgta cctttactga tgatgcagaa gaaatcggaa
     9781 gcaatcaatg tgaaagctgc gtgatctaat atcatagata gattcgctta ttcatatttt
     9841 aattaaagga gcattctcat gtcagaaaca tattatgaag caataaactg gaatgaaatt
     9901 gaagatatca ttgataaatc cacttgggag aagctgacag agcaattttg gctagataca
     9961 cgtatcccac tttcaaatga cctagatgat tggcgtacat tgtctcaatt ggaaaaagat
    10021 acagtaggac atgtatttgg cggtttgaca ctgctagata ctgtccaatc tgaaagtggc
    10081 atggatcagt tgcgtaaaga tgtccgcact ccccatgaag aagccgtttt gaacaatatt
    10141 caattcatgg aatccgttca tgccaaaagt tattcttcta tttttagtac actgaatacg
    10201 aaaaaagaaa tcgaagaaat ttttgactgg acaaatacga atccttatct gcaaaaaaaa
    10261 gctgagcgta tcaatgaaat ctacaaacac ggtacaccgc tagaaaagaa aattgccagc
    10321 gtctttttag aaacattctt gttctattca ggtttttata ctcctcttta ttatttagga
    10381 aacaacaaat tggctaacgt agcagagatc atcaaactaa tcatccgaga tgaatctgta
    10441 catggaacct acatcggtta caaattccaa ttaggattca acgagttacc tgaagcagaa
    10501 caagaaacgt taaaagactg gatgtacaat cttctttatg agctttacga aaacgaagaa
    10561 cgttatacag aagaattata cgatccaatc ggctggacag aagaagtcaa gacattccta
    10621 cgctataatg ccaacaaagc attgatgaac ctagggatgg atccactctt tccagatact
    10681 gccaatgatg tcaacccaat cgtaatgaac gggatttcaa caggcacaag caaccatgac
    10741 ttcttctcac aagtcggaaa cggctatttg ttaggtcatg tagaagcgat gaaagacgac
    10801 gattatttga ttggattgga ataaggattt attttaattc aaaaattttt cgaaaaataa
    10861 aaagagttta gcgtacagat attttaaatg tacactgaac tcttttttat gcttattcac
    10921 ttgtttcttc cagcactttt ggactgtcta acttttccga aacatgttcc attcttctca
    10981 ataaatagat tttccggata tttaatatta tcgtcttaat cactgcatag acaggtatgc
    11041 aaatcagcat gcctaatatt cctgcgacac ttcctgctcc aatcaatacc aagatgatcg
    11101 tcaaaggatg gatattcatt gatttcccaa ataacaacgg cttgatcaaa tttccatcta
    11161 attgttggat cactaaaatc gacaacgcca tatacaaagc ttgaaatgga gagataaaca
    11221 aaccgacaat gattgctggt accgctccaa taaaagggcc gacatacggg ataatattcg
    11281 tgattccgca aatgaccgca agcaacaagc tataaggctg atcgaatatt ctcattgcca
    11341 aaaagctcat tacaccaata atcaaagcat ctaagatcgt actgctgata taggcagata
    11401 atgtttcgtt taattctttt accgtttggc gtaactcttt acgaatcgct ttcggaaaga
    11461 agtgagacaa cgcatcaata aatttgtgcc catccttgaa cataaatagc aaaataaatg
    11521 gaacggtaaa taacaaaata aaaaattgca tcataaatga aatgattttt gagacacttg
    11581 cagataaact gactaatatg atattgaaca aattactaag agataaattt gctgatgcta
    11641 attgttcttc caaattgaaa tttttaaact cttcccgctg cgccaattca tttaaccatt
    11701 tgcttgtttc atctgcatac attggcaagc tctgggtcaa ttgaattgtc tgttccatta
    11761 actgaggcac tacattcatg acagttaaaa caactaaaat gattacgacc aaaaacgtca
    11821 ataaaaaacc gaacactctc gggatccgat gcttttcgag aaaaacaacg attggatcga
    11881 acatataata gataaaacca gcaacaagca atggtaaaaa aattgccgaa agcattttca
    11941 atattggact aaaaatattc ggcatttgta aaataaagta cacgccgatg atcgtgagta
    12001 ctagctccac tgtccagaaa aataattttg attgtttaaa acgtgattgc atacatctcc
    12061 tccaaggtcc tttgatactt ctattctatc atttaacaaa gagttacgcg ctgagatttt
    12121 catttgctta aaaaaaacaa aaaaaataaa catattttaa tgagtagacg agtacttaaa
    12181 caaaaacacg gtttggagta gtgacaaaaa ttatactgca gtcccttttt ccaaataaac
    12241 ggtgttcaaa agcttgcatc ttcgtaataa gcccagccaa acgaaaaata taaggaacta
    12301 tttttatttg gctgggctta ttacttgatg taggacatct attttacaac ctcagatcat
    12361 ttattgcgca atactgacta aatgcaactt tgtgatattt ttgtgtacgg acaactcctc
    12421 gatcacatcg gcataagtga gcccttttgg aagatcaatc gtatagatat ttttgtacac
    12481 tcggtagtca tcaacgaatt ttacgtcaaa attcacatct tcgattacga tatttttctc
    12541 ttcaaaataa tcggtaagaa aatctttggt ttcttttcta tggataaatt ggatttctaa
    12601 ctttttagtc gtaggtacat ggatcacgcg tttcactact gtgagtgcaa tagcaatccc
    12661 gataaaactg atgatcgcaa tggaatagta acccatgccg atggcgatcc ctaatccagc
    12721 aattgcccat aaagaagcgg cagtcgtaag tcccgtcacc gattgtttcg tgacgatgat
    12781 cgttcccgcg cctaagaaac cgacaccact caccacttga gcaatcagcc ttgcttcatc
    12841 tgaacgaatc gttccagcaa gctgtggata ctctaaagca tctcttaatg caccactagc
    12901 gatctcaact tggatcaatg caatgataca tgctcccata caaactaaaa tatgcgtacg
    12961 catacctgct ggacgatttt tatattgtcg ttcaaaaccg attgctccgc caaatagcat
    13021 agcgatccct aaacgtaaaa taatctctgg aattgtcaat accatatcat tcatctaaac
    13081 accctccagt ccaatatatc atgtctgaaa ggagcagaca aaaaaagtgc aatttttacc
    13141 tcttacgaaa aaaggactgt gacaaaattt ttgtcatagt cctttttatg aataaacggt
    13201 gttcaatcag ctgaccctcg gtattactca acaaacggca aaatatgggg agctattttt
    13261 cctttgtctt ctctaatact caggtcaaaa cgctgatttc acaacctctt tagcctacta
    13321 ttgaaaatta caacttactt gctgcttctt catcgatgat cacaacaaca ttgtcgtgat
    13381 tttgcaatac acttgctggc aaatgattcg ttacaggtcc ttcaatcatc cctttgattg
    13441 catcagcttt gctttcgcca aatgccatca agacgatttc tttacttttc ataattgaac
    13501 cgattcccat tgaaacagct tttgttggta catcttctgc tttatcgaag aatcgtttgt
    13561 ttgcattgat tgttgattct gttaagtcaa ctactgaagt cgttccgtca aatgaagcac
    13621 caggttcatt gaaaccgata tgtccatttt gcccgattcc taagatttgg atatcgattg
    13681 gatgtgcatc gatgatttga tcatactttt tgcatgctgc ttccagatct tctgcttttc
    13741 catctggtac aaacgtttct ttgaatggtt ttttatcaaa taattggaca tccatgaaat
    13801 gacggtagct ttgttcatct gaaccgccta gtccaacgta ctcatctaag tttacagaag
    13861 tcatttcact gaaatccaaa tcgcttgaag tcatttcttt atataaagta actggtgtgc
    13921 ttcctgttgc caatcctaat acttttgcac ctttgttcat accttctttg atgatttcaa
    13981 atgctttttt tccgccttct tcagcgtttt ttacacgaat gatttccata gtgattgctc
    14041 ctttatattt tggtatagcc caattatagc attctttttt tctttttaca ataattagta
    14101 tagaccaaat tgcatttttt tcattttctt gacaataaat aggaatccgt gttaggtttc
    14161 ataagatggt tcaatcaaac aatccatgtt gcatgaaaac caagcaagtg attcactgtg
    14221 gacgctttat gtctgcagtt tttttatgaa aaaggagtta ttatgagtat actgacatta
    14281 aacaacatta cccagcaatt tggcgacaaa atcctctatg aaggtgtcga tctgcaatta
    14341 aatgctggcg aacatcttgg gctgattgga caaaacggag ccggtaaaag tacattgatt
    14401 aaaatcatca ctggtgagat cttaccagat gacggacaga tccattggca aaaaaatatt
    14461 cacaaaggtt acctcgatca atatgtggaa gtcgatgaaa cattaacaat cgaagaattt
    14521 ctaaaaactg cgtacgcaaa agaatacgaa aaggaagaaa aaattgcttt tctttaccaa
    14581 acatatagcg agaccttcga tgattccttg ctggaaaaag ctgggaaact ccaaacggaa
    14641 ttagaccaag gagtgtttta tcaaatcgac accttagttg ctgagatgag cagcgggttg
    14701 gggatcgatg tcttaggttt agattcactg ttgaaaaatc taagtggtgg acaacgttca
    14761 aaggtgattt tagcaaaact acttttagaa aacccagatg ttctgatctt agatgaacca
    14821 accaatcact tagatgatca gcatatccaa tggctgacgc agtttcttca ggattttgac
    14881 ggtgcgtata tcgtgatttc ccatgaccaa gaatttcttg atcagatcac cacccatatc
    14941 gcagacatcg agtttggaaa gattactaag tatactggcc atctaaaaca agcattgaaa
    15001 caaaaggaac aaaatcgcga aagctatttg cgccaatatc atgctcaaca aaaacaaatc
    15061 gaaaagaccg aagcttatat tcgaaaatac aaagccggtt cccgatcaac gatggcaaaa
    15121 agccgacaaa aacaattaga taaaatcgaa cggctgacgc ctccagcttc agcaagtaaa
    15181 gctgtctttg attttccatt ctcgcctatt gtcacgacat tagcagtgga aacaactgat
    15241 ttagtcatcg gatatgatcg accgctactt gcacccatca atttgaccat ccgctttggt
    15301 gaaaatattg ccattcgagg cttcaacggg attggaaaat ctactttatt aaaaacactg
    15361 atcggtgaga ttgaaaaaat aagtggcgat ttccacttcc cagataacac aaaaatcaat
    15421 tacttttcac aagatctgta ctgggaaaat ccattagaaa caccactaca atatttaagc
    15481 agtcaatttc caaaagcgac tatcaaagaa ttacgtcgcc aactagctaa agcagggtta
    15541 gttaatcaat tagcaagtga acctctcact acattaagtg gtggggaaca aactaaggtg
    15601 aaacttgcac agttgacaat gaaccaaggt aatttactga ttctcgatga accgacgaac
    15661 catatcgatc aagaaacgaa agaaagctta caagacggga tacagaaatt tccaggaaca
    15721 gtaatcatcg tctctcatga acaagaattt tatcaagatc ttgtgcaacg agtcattgag
    15781 attgaaccaa aataaacgtt tgattgaata gttgaaaaaa aggagctgtg acaaaagttt
    15841 tgtcacaact ccttcttctg aataaatggt ggccaattag ctgaccttcg gtattagctc
    15901 aaaaaacggc aaaatatgag gagctatttt tatttggcta ttcttattac ttgatgcaga
    15961 acagcttttc acaacctctt ttcgtctatt ttttattttc gagatttctc tttcctttaa
    16021 aaacaactgt ttgaaagaag aacgcacatc cttgaaaaac aagcccgcta accgttacac
    16081 ctaaccagcc atactgctgc cacattgtcg tccctagcaa tgaaccagcc gcacctccaa
    16141 taaagtacat aaacataaat acagacccgt ggtgctagtt aattttaata tcctaaagaa
    16201 tatctcaaag ttccttcaaa acgtcgttgt gctcgactta atagaacact gtaagccagt
    16261 aatatgcttt caaatctact ctctagccct ttaacagaac gtgagttgaa attttgacaa
    16321 cctaattttt ctaaggaaga aa
//
LOCUS       DADVXM010000057        15877 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.060, whole genome shotgun sequence.
ACCESSION   DADVXM010000057 DADVXM010000000
VERSION     DADVXM010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.060"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(321..521)
                     /locus_tag="KB927_001915"
     CDS             complement(321..521)
                     /locus_tag="KB927_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6840831.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(826..2058)
                     /locus_tag="KB927_001916"
     CDS             complement(826..2058)
                     /locus_tag="KB927_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBB6840832.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            2313..2882
                     /locus_tag="KB927_001917"
     CDS             2313..2882
                     /locus_tag="KB927_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6840833.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(3060..3500)
                     /locus_tag="KB927_001918"
     CDS             complement(3060..3500)
                     /locus_tag="KB927_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBB6840834.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            3658..4422
                     /gene="map"
                     /locus_tag="KB927_001919"
     CDS             3658..4422
                     /gene="map"
                     /locus_tag="KB927_001919"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBB6840835.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            4454..5377
                     /locus_tag="KB927_001920"
     CDS             4454..5377
                     /locus_tag="KB927_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBB6840836.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            5453..6592
                     /locus_tag="KB927_001921"
     CDS             5453..6592
                     /locus_tag="KB927_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBB6840837.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            6585..7385
                     /locus_tag="KB927_001922"
     CDS             6585..7385
                     /locus_tag="KB927_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6840838.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            7385..8212
                     /locus_tag="KB927_001923"
     CDS             7385..8212
                     /locus_tag="KB927_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6840839.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            8190..8924
                     /locus_tag="KB927_001924"
     CDS             8190..8924
                     /locus_tag="KB927_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6840840.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            9024..9890
                     /gene="rfbA"
                     /locus_tag="KB927_001925"
     CDS             9024..9890
                     /gene="rfbA"
                     /locus_tag="KB927_001925"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBB6840841.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9904..10476
                     /gene="rfbC"
                     /locus_tag="KB927_001926"
     CDS             9904..10476
                     /gene="rfbC"
                     /locus_tag="KB927_001926"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBB6840842.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            10498..11526
                     /gene="rfbB"
                     /locus_tag="KB927_001927"
     CDS             10498..11526
                     /gene="rfbB"
                     /locus_tag="KB927_001927"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBB6840843.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            11624..12475
                     /gene="rfbD"
                     /locus_tag="KB927_001928"
     CDS             11624..12475
                     /gene="rfbD"
                     /locus_tag="KB927_001928"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBB6840844.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            12509..14542
                     /locus_tag="KB927_001929"
     CDS             12509..14542
                     /locus_tag="KB927_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840845.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPAKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKIDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKEIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            14586..15866
                     /locus_tag="KB927_001930"
     CDS             14586..15866
                     /locus_tag="KB927_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBB6840846.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIATLLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
BASE COUNT         4883 a         2735 c         3287 g         4972 t
ORIGIN      
        1 ataaaaatct ttgataaatc tattcgaagg gtcaaattta aaccataatt gtgtttttcc
       61 ttccatcagc ataaaagttc acctcaaaaa gagtatacga acgaatgttc tttttgtgaa
      121 ggcggaattt aatatactga ataatagaaa acaagtactt gtgccaaatt atgtgccaaa
      181 aaaattcgaa ttcaacaaaa tgtaaacaaa tagaaaacct tctatattaa gatttcctgc
      241 aataacaaac acaacagaag acgtgtaata gttagtcagg aacgtacaaa taacccctgt
      301 atcctttgcg gtacaggggg ttattttgta taagtagaca ttgtagtttc taaactgcta
      361 tgtcctaaac gtttcgatac gctaagtata tttactcctt gataaagtaa aatagatgca
      421 tgcgtatgtc ttagtccatc aataaacagt cgaagagaaa atagggaaaa attgattact
      481 aaagaaaaac ttactaggtc gacggtgtag ttgattttca tacttcaata gattcgaatt
      541 aaacgatttc gattggctta taccagtcct atccaacgaa agatatatcg ttcttaactc
      601 tagcggtata acttgaagct ttacgtaaag ccaatgggaa tgaactggag atgacttttt
      661 attattttta gtaatagctg atgggttaat acttacaact ttccttttca aagtaccata
      721 taaaaaaacg gtggggttgt ttagcgaaat aaaggatcta agccaatagc ttagatcctt
      781 tattctatgc tttatattat tttttgcatg tgtgcgaaag tatactcaag cccaatcgcc
      841 atttcggaaa atcggtactg tagagccatc ttcacggatt ccgtcgatat ccatcttgtc
      901 agatcctacc atgaaatcta cgtgggtttg acttctattc aatccagctt ctgctaattc
      961 ttcatcggac atttctgtac cgcctttcac actgaaggca taagcagaac ctagtgctaa
     1021 gtgattcgat gcgttttcat caaataatgt attgaaaaag atgatgccag attgagaaat
     1081 aggtgaaggg tcaggtacaa gtgcgacttc tcctaaacga cgcgcacctt catctgtatc
     1141 aagcagtttt gctaagacat cttctccttg ttcggcagaa aaatcaacaa cttttccatc
     1201 tttaaaagta aatttcatac ccgagatgat ggtgccagca taactcagtg gctttgtact
     1261 tgaaatgtaa ccatctactc gatgactgtc aggtgctgtg aacacttctt ccgtcggcat
     1321 atttgccatg aatttttctc cacgagcatt atagcttcca gcgccttccc aaagatggtt
     1381 tttaggcaat ccgataatga tatctgtacc gggagcagta tagtgaaggg cagaaaattg
     1441 ttctcgattc aattcttctg ctttttttgc taatttttca tcatgcttct tccatgctaa
     1501 gacagggtct tcttcataga cacgagtcgt tttgaaaatc tgatcccata atgcctcaac
     1561 ttgtttttct tctggcagtt ctgggaagac ttttgctgcc cattgtttac cagccgcagc
     1621 cacgacagtc caactgactt tatttgcttg agttgccttg cgtaaattca ttagtgcttt
     1681 gccattcgct gattgataag acgctactcg atggctatct acaccagcaa atgcatcggg
     1741 atcggcagaa acaacgctga tcctgcttgc tcctttttca agccattcat ccgcttgatc
     1801 gattttagat tgtggtacat tctcaatacg atccgttgca gcatgtaaaa gaaattctct
     1861 ttggatctgg tcgtcagtcc attgaacgat aacctcagcg gctcctagtt tataagcttc
     1921 ttgtgtgatc aatcgagcaa ggggtgcctg ttccacgctg atctgtaaaa caactgtgtg
     1981 tcctttttct gtggctacgc cagtttctgc aattaagcgt gcatattttt ttagaagttc
     2041 attaaaatca gataacataa taaaaattcc tcctcaccat tttttctggt aactattagc
     2101 atgataccat ttaattatga ttcaaacaat gaggctttaa ataaaaaaag gaggttattt
     2161 ttttaaggtt aagtttcatg atatatgtta ctacttgcta tttcagcttg tgaagaaaat
     2221 caaaaactaa ttttgcatat caaaaaaaac atgttacaat gaaattaatc aatggtggaa
     2281 gcgttataaa aaaattaagg agattaaaaa atatggcaag aaaaaagacg attactagag
     2341 aacagatttt ggcagctgct tatgaagtag ctgccaccga tggatttaca cgatttactg
     2401 cgagaaacat cgcgaacaaa atgaattgtt ccacgcaacc gatttatctt gagtttaaaa
     2461 atatggatga cttgagacaa gctctttttg agcagatcta tgatcattta caatatgaag
     2521 tgttcactgt tgagcataca gggaatacga ttatcgatct tgcttttaat tatatccatt
     2581 ttgcaagaag agagaagaag ttgtatcgtt cactgtactt agaagaatat ggtggaggaa
     2641 aagagatgca gaatttctct tatacttact ttgtgaatac agtgaaacgc gatccagctt
     2701 atgtgaatct ttcagaagag cagatcgaat ctttgtataa tgggacatgg atcatagcta
     2761 ctgggatcgc agctttgatg tcttcaagca tcatccatcc aactgatgaa cagattgaaa
     2821 agatgatcca agacagtata gatgctatct tgaaattcaa agaaccaatc gaaatcgatt
     2881 gaatatactc aaaagttcca caaatcagta ggtaacaaga gatgtgtcaa aataaggaaa
     2941 agttcgtttt tcttacagcg tatgcatttt taactcccga agaactcttc catgaatgca
     3001 atgaataaaa gagccataca gattgaataa atctggatgg ctcttttatt gcaagtatat
     3061 taaatttttg cgactagttc tttagcgaaa gcttctaaat tttcgatatc ttcttcttca
     3121 gcattcagat ccactttaac attttcggct ccttttgatg cgcctgtttt tgcaaaagca
     3181 gcatcgaaat catccaccga tttgcagaat tcatcgtaaa aagtatcacc agatccgcag
     3241 acaccgtaaa tttttcccaa tagatccaat tcttgcaagt cttcataaaa gtctacgatc
     3301 tcatcaggca gatcgccatc atcgtatgta taagtagcta ctacgcaaat atctgcctcc
     3361 tcgaattcat ctgcatctac ttgggtacat tcgttgattt cgacttcgat atccagattt
     3421 tcaaatgctt ctgcaacaat atcggcgatt tcttcagtgt ttcctgtcat gctagcatat
     3481 acgatttttg ctaaagccat gatgtgcctc ctcgtttata attatttaac aattatgaat
     3541 tataccaaaa catcattgaa aagaaaataa aacctagaga cacctgggga atgtcatttg
     3601 gctaaatgta tgccgctatg ttaaaatgag agggatttgt aaaaaggaga cgaaaatatg
     3661 attactttaa aatcagcacg tgaaattgaa atgatggcag aatctggagc tttattagca
     3721 gatgtacata aaaatctgcg tgattttata aaaccaggaa tcacaagttg ggatattgag
     3781 gtatttgtca gaaactatat cgagagtcat ggcggaattg ctgcgcaaat tggctttgaa
     3841 gggtatgaat atgcgacttg tatcagtata aatgatgaaa tttgtcatgg attccctcgt
     3901 aaaaagcctt tgaaaaacgg tgatttggta aaagtcgata tgtgtatcga tttgaaaggc
     3961 ggcatttctg attcttgttg ggcctatgta gttggagaat ctacacctga gatcgaccga
     4021 ttgatggaag taacgaagaa agctttgtac atcggtattg agcaagcaca agtagggaat
     4081 cggattggtg acatcggtca tgctatccaa acttatgtag aaggcgaaaa tctagcgatc
     4141 gttcgtgatt ttattggtca tggcgttggt cctacgattc atgaagaacc agcagttcct
     4201 cattacggag aagctggaaa agggttgcgg ttgaaagaag gcatggttat cacgatcgaa
     4261 cctatggtta ataccggaac ttggaaaatg aaaatggatc ctaacggctg gactgcgtat
     4321 acaagagacg gcggactttc ttgccaatat gaacatacat tggctattac taaagatggt
     4381 ccaagaattt tgacatcaca aggagaagaa ggcacttatt gatctatcca gtcaataggt
     4441 acgggagagg tacatgaaag tttggaacaa aataaaacaa aatgaaaatc tgatgcgctt
     4501 tattgagacg actcaaaagc gcatcactga ttcagaaatg agtacgacct ctgtcgtcgt
     4561 tgcttattat ttactcttgt ctttatttcc attgattatt gcttttggta atattttacc
     4621 gtttctccac atcgatcaag agactgtact gacctattta cgagaagtga ttcctgagac
     4681 cgtttaccag tttatcggtc ctgcaatcaa agaccttttg acacaaagtt caggaggctt
     4741 gttatccgtt tctgcattag cggctttatg gtctgcaagt caaagtatca atgctttgca
     4801 aattgcgatg aataaagcgt atggcgtaga aaatagaaaa aattttttga tcgtccgttt
     4861 cttctcacta attgtcattg tcttgttcat gattgctatt agtggggtaa ctatcgttct
     4921 tgggttggga cagctgattt tggatgctat tcagccaatc gtacaaatac ccgtgaactt
     4981 tatcgatcag ttccaaactt tgaagtggcc aatcacattg gtagctttat ttgtcatcat
     5041 gttcttgatt tatttaattg tccctaatgc tcagttgaag ttgaagacga tcattccggg
     5101 cacgatcttc gctactgtcg gctggatgct gttatcacaa gtgtttagta tctatgctag
     5161 gtattttgca acgaggatca gcggttatca gatcatagga agttttattg tactcatgct
     5221 ttggcttaat tttgctgcta cgatcatcat tttgggcgga atcatcaatg cagttgttca
     5281 agaatacgtg acgggtcatc aaatcaaaaa acgtcgagat ccaagccgaa aatggttcaa
     5341 taaattgaaa actaaatttt ctcataaaaa aaagtagaaa caagagttct tattgtaaat
     5401 ttatatcagt aatttataat aattatgact cttaattaaa gtaggtgccc atatgcttgt
     5461 ttcttttagt atggttataa gattttttct gacaatttta ttatcactga tattaacacc
     5521 tgtattcaaa atcatttcag tacaaacagg tatggtcgac aaaccaaatg aaagaagaat
     5581 aaataaagtt ccaatgcctt cagcgggcgg actgcctatc tttatttcat ttgttatatc
     5641 gactttattc ttattccgta aaattatccc tcaatcgtat attgtaccga tcttgattgc
     5701 ttctttagta atcatagtca caggagtgct cgatgataaa tatgagctga cacctaaaca
     5761 aaaaagtata gggatcttga ttgcttctct tattatttat tttgtagcag atatacgtat
     5821 tgattccttc acgcttcctt ttattggata tatccaacta ggctggctta gttttcccgt
     5881 aacgattttt tggatcttcg gtatcacgaa tgcggtcaat ctgattgacg gtttggatgg
     5941 gctggcggca gggatttcat tgatcggttt aattacgata ggaatcattg gatatttttt
     6001 cctccatgct tctacagtgt atattccagt tgttattttc tgtcttgtag caagtattat
     6061 cggttttttt ccttacaatt tttatccggc aaagatttat ttaggcgata caggagctct
     6121 attcctaggg tttatgatgg ccgtcctttc actacaaggg ctgaagaacg tgacttttgt
     6181 ttcatcgatt tctttgctga tcgtcatggg agtgccggta acagacacgt tttttgctat
     6241 cattaggaga aaagcaaacc gtgtttcttt ttctacagca gataaaaaac atcttcatca
     6301 ccgactaatc agtttaggct ttactcataa aggtgctgtc ctgacgattt atgcgatggc
     6361 tttgatgttt tctttcacag ctatggtcat gaattatact ggaagaatcg gaacgatcat
     6421 attgattatt gccatgttgt ttgctgcaat tttattattt gaattgattg gtctgatcaa
     6481 tgagaaacat cagtttattt taaaaacatt gcgattttta gggaataaag agtaccgtac
     6541 gcaagtaaaa cagaaatatt tgaagaaatg gaaccgtcat atagatgaat aacaaattaa
     6601 accagccgat ccttattagt attgtgacgg caaacagtga taaaattttt cggacactag
     6661 ataattttat ttcaactgta aaagatgaaa cagcagtaaa aatccgaatt tttgacaaca
     6721 attcacttcc cgagtacaaa aaaagactaa cagagtatag gaaatatccc tacatcgata
     6781 tctattttca tgatgaaaat tccggatttg gttatggaca taatcacaat ctgatagcta
     6841 gcgattctcg ctatggcatt atttgtaacc cagatatttt agtggatgaa gagacagtta
     6901 cagcattggt cttgttattg aaagaacatc cggaatgtgc gatgttagca cctaagattc
     6961 ttaatgaaga tggaacaact cagcacctca tccgtgagca gctggctgtt tttgattacg
     7021 ttttgcgctt tgtgcctttc aaatgggtca aaaaaaagtt tgacaaacga ctggctgtgt
     7081 ttgaatgccg aggattgcct actgatgcta atagttatgt acggatgatc tcaggtagtt
     7141 ttatggtagc tgatattgat aaatttaaag agataaaggg gtttgatgag cgtttcttca
     7201 tgtactttga agacaacgac ttgtgtttga gttttgaaaa agcaggttac aagttattgt
     7261 acacaccctt ttatgcagtt atccattttt acgggaaggg tgcgcatcga aatgcaaaac
     7321 tgtttcgcgt gtttttgact tctatgatga aatttttcaa taagtggggg tggcgttttt
     7381 tctgatgaaa ccagaaatat tagtagtcgt tgtgctttat cagcaactat tcagtcaatc
     7441 tccagcttat ggaccattaa gcaaagcact tagcgaaaag caaattcagc ttattattta
     7501 cgataatagt cctcaaaggc agcaaaatga gctgtttgaa aaagaaaata tcgtttatca
     7561 tcatgatccg caaaatcctg gtttagcggt ggcttataat tttgcgttgt ctcaagcaga
     7621 tgaaggaaca cgttgtctcg tcactctgga tcaggatacg aggctagtcg acgattattt
     7681 tgaactattg cgtaaagtaa cctttacaga tgaatgtgtt gctgcagttc cgatgatttt
     7741 ttctgggagc cgacaagttt ctcccctata ttcagatcgt tatatcaatc gtacagctca
     7801 agcagtagaa gttgaaggcc caacagctga acgaatcatg gcaatcaatt caggtgttgc
     7861 ctggtctgtc aaatttctaa aaaagattgg cgggtttaat cctgcttttt ctttagattt
     7921 tttggatcat tggctgtttt ggaaagtgga tcagttggaa aaaactgtgg agatccttcc
     7981 tgtacgaatg gaacatgatc tttcggtttt agactatgaa aaagtttcaa gtaatcgata
     8041 ccgttctatt ttacaagcag aaaatcgatt ttatcatgaa tatgatcaaa ggcatttatc
     8101 cagtcaccga cgacaattat tgttaagaac agctaaacag ttcttgaccg tcaaaaaccg
     8161 gcatatctgg cggatgactt tgcgctcata tgttaagaat tggaaggtgt gaattcgtgc
     8221 gttcggtttg tatagctacc tttaatggag gcagatattt aagagagcag ttagatagta
     8281 ttttatctca gctttcagca gaagatgaag tagtcatttc tgatgatggg tcagtagatg
     8341 atacatggga tatattaact gaatacgcag aaaaagataa gcgaatccag cttttttcgg
     8401 ggcctcgtca aggattgatc gctaattttg gttatgcgat ccagcagacg aaaggagatc
     8461 taatcttttt ggcagaccaa gatgatgttt ggttggagac aaaagtgaaa aagatcactg
     8521 actattttga gcagaatccg gatcagctag tagtagtttc tgatttaatc attgtggaca
     8581 gcgagctgca agagatccat gattcgtatt tttcgtttcg aaattccaaa gaaggatggc
     8641 ttaataatgt gataagaagt cactatattg gtgctggtat ggctttccgg tcttctttaa
     8701 aacccgatat tttgccgatc ccgtcagaag tgccgatgca tgatatgtgg attggtttgc
     8761 tgggaggaaa gaagactggg ttcctaagag aaccgttaac tctgtaccga agacatgatt
     8821 taaacgcgag tgagattgaa acacattcta aattacggca aaaaatttct tggcgtgttc
     8881 atctgattac ggcgttgatc aaacgaaaat ggtttaaacg ttgataaaag atgtttaaat
     8941 ccttaatatt tccatgacaa atataacaat tgatgagata ataacaaagt gaaatttgaa
     9001 atcaaaaagg agagcagata tccatgaagg gaatcattct tgctgggggc agcggaacac
     9061 gtctgtaccc tttaacaaag gcaacatcga aacaattgat gccgatttat gacaaaccaa
     9121 tgatttatta tccaatgtct actctgatgt tggcgggaat caaagaaatt ctgattattt
     9181 caacgccaca agatacacca cgtttcaagg aattatttgg aaacggaaat gatttaggac
     9241 tgcagatcga atatgcagta caagaaagtc cagatggatt ggcacaagcg tttatcattg
     9301 gagaagaatt tattggagat gatagtgtct gcttggtatt aggggacaat atttactatg
     9361 gtggcggtct gtctaaaatg ttgcaacgag cagcttcaaa agatacaggc gcgacagtat
     9421 ttggctatca tgtcaatgat ccagaacgct ttggtgtagt agaatttgat gagaatatgc
     9481 aagctttgtc gattgaagaa aagcctgctc agccaaaatc aaattacgct gtaactggcc
     9541 tttattttta tgacaatgag gtaatttcta tcgctaaagg tatcaaacct tcagaacgtg
     9601 gagaactaga gattacggat gtcaataaag catatttgga taaaggaaaa ctatccgtag
     9661 aacttatggg acgcggattt gcttggcttg atacaggaac acatgaatca ttgcttgaag
     9721 catctacctt tatcgaaaca attgaaaaac gtcagaactt aaaagtggct tgtttggaag
     9781 aaattgctta ccgtatgggc tacatcgata aggaacaatt gctggccctt gcacagccat
     9841 tgaaaaaaaa tcaatacggt caatatttat tgaatttggc cgctgaataa ggagtcctta
     9901 cagatgaaag taacagatac aaaattaaca gatgtcaaaa tcgtagaaat ggacgtcttt
     9961 ggcgatcatc gcggtttctt cacagaaagt tattcaaaag caaaatttgc agaacatgga
    10021 ttgaaatatg actttgttca agacaaccat tcactatcag ctgaagctgg tgtccttcgg
    10081 gggcttcatt tccaaaaagg agaagctgca cagacaaaat tgattcgggt agtcactgga
    10141 gcagttttag atgtagtagt ggatatccgc aaaggtagcc cgacttatgg tcaatgggac
    10201 ggatttatct tatctgaaca taatcatcga cagttgcttg tacctaaagg atatgcccat
    10261 ggattcgtta ctttgacacc aaatgtgaac ttcctttata agtgtgataa ttactataat
    10321 gcagaagcag atgggggcat cgcatttgat gatccagatt tagcgattga ttggccaatt
    10381 gatccatcaa gagcgattat gtcggaaaaa gatcaccgtc atccgacatt aaaagaattt
    10441 gaagcagaaa atccatttgt ttacggagaa atctaagaat taaggagaaa ttttcttatg
    10501 aaaaacatca ttgttaccgg aggtgccgga ttcatcggct ctaatttcgt tcattacgtg
    10561 gtaaacaatc atccagaagt gcatgtcact gttttggata aactgactta tgcaggaaac
    10621 aaagagaact tggctggact tcctagcgat cgcgtagaat tggtcgtagg agatgttgca
    10681 gatgcagaat tagtggaccg tctagtaaaa gaagcggacg cagttgttca ttacgcggca
    10741 gaatcccata acgataattc attaaaagat cctttcccat ttgtacaaac gaatatcatt
    10801 ggtacgtata cacttttaga agcttgccgc aagtatgatg tacgctatca tcacgtatct
    10861 actgacgagg tttacggcga tcttccatta cgtgaagacc tgccaggaca tggggaaggc
    10921 gaaggagaaa aattcactgc ggaaacacca tataatcctt caagtccata ttcttctaca
    10981 aaagctggtt cagatctgtt agtaaaagca tgggtgcgtt cttttggctt acgtgcaacc
    11041 atttcaaact gttcaaacaa ctatggtcct tatcagcata ttgaaaaatt tattcctcgc
    11101 caagtaacga atatcttaag cggtattcgt ccaaaattat atggcgaagg aaagaatgtt
    11161 cgtgactgga tccatacgaa tgatcattct tcagcagtgt ggctgatttt gacgaaaggc
    11221 agaattggcg aaacctatct gatcggtgca gacggtgaag aagataataa gaccgtgatg
    11281 gaattgatct tagaaatgat gggtcaacca aaagatgcgt acgaccatgt aaacgaccgt
    11341 gcaggacacg acttgcgtta tgcaatcgat tcgacaaaat tacgggaaga gttaggatgg
    11401 aagcctgagt ttacgaactt ccgtgatggg ttggctgaca cgatcaaatg gtacgaagaa
    11461 catgaagact ggtggaaaaa agaaaaagag gccgttgaag cagcatatgc caaaaatgga
    11521 caataataca gagaaaatgt cactgtatta atggaaaaac acatgtgagg caggcgctcg
    11581 cctgtctctt ttttaaaata aaaatcaagg agcggataat catatgtttt tattaactgg
    11641 aggaaatggg caactaggta cagaattgcg ccatttatta gatgaaaaaa atctgcaata
    11701 tgtttcaaca gatgcaaaag acttggatat cacagatgcc gagaaaacaa tggcttacat
    11761 cacagaatta aaacctgatg ttattttcca ttgtgcagct tacacagcag tagataaagc
    11821 agaagaagaa gcaaaagaat tagatgagaa gatcaatgtt gatggtacaa gaaatgtagc
    11881 acttgcagca aaagctgtga atgctcaatt cgtctatatc agtacagact atgttttcga
    11941 tggaaaaaac aaaaatgtag aatacgaagt agacgaccaa acgaatccac taaatgaata
    12001 tggtcgtacg aaattattag gcgaaaaagc agtagaagag attttagaag actattatat
    12061 catacgaact tcttgggttt tcgggatcta tggacacaat ttcgtcttca cgatgcaacg
    12121 cctagcggaa acccgcgaca aactgactgt agtaaatgac cagtttgggc gaccaacttg
    12181 gacacgtact ttggcagaat ttatggtata tgtcatcgaa gaaaaagcac catttggtat
    12241 ttatcatttg tcgaacgaaa atagctgttc ttggtatgaa ttcgcaaaag aaatattgaa
    12301 agatacagat gtagaagttg cacctgttac gtcagaagaa tttccgcaaa aagcaacacg
    12361 tccgcagtat tcagtcatga gcctgaaaaa gacagaagag ttaggatttg tcataccaac
    12421 ttggcaagaa gcacttgcgc aaatgctgga agctgccaaa aaaatgaata agtaatttcc
    12481 ttttatcaaa tagaatttgg agcatgatat ggaaaaacaa acaagaagtg cacgacgaaa
    12541 agaaaagcca aaagcgaacc aggcagattc gaatttggtg cttgacctgt ttctaaaact
    12601 ccgctatctt attggcgttt tagtcatcgt ggtcatcgtt acttttaatt taaacggaag
    12661 ttcacttggt gtttgggata aatatgtgtc gcaaagagac gatgggaaaa aaactgatgt
    12721 gatttttgga cagaatcggg aagtgcggtc agacgaatgg ctggtgcaga caccttttta
    12781 cctctcacaa gctgaagagg actttccgtt ggtgaacgag gattattcat taaacggaca
    12841 aaacatgatc attgcgtata attctcctgc aaaggatatt acggttatcg gaaaaccatt
    12901 caactgggga ttctttttcc tcggaagaga tcgaggactt tccttttatt gggcgatgaa
    12961 attagtcgtc atggtcttgc ttggattcga agtactgatg atattaacga agagaaaaaa
    13021 agctctatcg ctaatcggtg catttgcgct gacattttct ccagcagtcc agtggtggtt
    13081 catgcaacat gtgggcgatt tgattttctt tactttggga ctgatgactg ctttttatca
    13141 ttatttctac aatcatgata aaaaatggct acgaacgttg atgatgcttt tggtggttat
    13201 tttcggtatt gggtttattt tagtgattta cccagcccat caagtgatgc tggcgtactt
    13261 gctgattttt tattttgttg gcctgcttat ttactatagc aagaaagttt catgggatct
    13321 gttggatgta gtgttgattg gaggggcagt tttatttatt ggcggagtca tggttcattt
    13381 ctggctaacg tcaaaagacg cattgttagc ttctttgaat accttatatc caggaaaacg
    13441 ggtaagtact ggaggaaagt ggacgattgg cgaatttttt tctttcctta caaattggaa
    13501 aattcctttt gaagatatca actattcgaa taactctgaa gtggccctgt tctatcactt
    13561 ttttccaact gtattcctag caagtccatt tgtgttattt ggcaaaaaag atagcgaaca
    13621 aaagttactg ggacgtattt tgatgatttt ttgtctgttt tctatctttt ggattaccgt
    13681 tgggttgcca aaatggctag cagaaatcac tctgctgtct tatgttcctc cattaagagc
    13741 catccttact tttagttttg cggcttgttt attatcgatc tggtttatcg cttatatttg
    13801 gagagaagat gttattccta tttggtataa attcattttg ttggcagtaa atgcatggtc
    13861 ttatttctat gcgattacgc attcgaaaat agataattat ttttcggatt ttgaaaccat
    13921 cgcagttgct gtgttgggaa cagtgatttt agcatttgca ttatttggct ggagacgctt
    13981 gttttacctc gcttttgccg ccttagttat cgtatctggc tttttcgtca atccagtcgt
    14041 agaaggtaca ggagcgattt ttgaaaaaac actggcaaaa gaaatccaaa aaatcgatca
    14101 acaagatcct ggtaaagttt ggttgtctga agatgaatta tataacttca ccccaacatt
    14161 gggagtgaaa tccttcaata cagtacgctt ttatccagat atagctgcat ggaaggaaat
    14221 cgatccgaaa gaagaatacg agaagtatta taatcggtat gctcatacaa gagcttttat
    14281 cgctaaggaa gatacaaagt tcattttaga tcgtccagat atgttttcgg tcacgttgaa
    14341 ttttgaagac gcagaaaaat tagggatcga ctatgtgatc agtaaacgac cattaactga
    14401 ttacaaccaa ttatatgaag cgcagttcac gcagctatat ggaccggata aagacggtta
    14461 tatgattttt aaagtagaat atccggatta tccagatgta ccacaaacac aaactcagga
    14521 aaatcagcta gtcgtacagt aataggctag ctgagaataa tcctgaaata ttagtagaaa
    14581 ggagagtgga gataattcaa gcaatcgtac aaaaatttgt caacaaaatg agtgtcggtt
    14641 tcttgctttt gttgctgacg ctagtctttt ttgtttggac agcagggtta ggttttccag
    14701 caactttgtt tatatataac aatagttcat tacttatcgc ttttagtgtg gctattttgc
    14761 tcattttaaa tgtttataaa gcaaaaggcg tcgattttct ttatctaggt gttgcgcttg
    14821 cccttttcat tttcttttct tactttcggg aattaagaaa tgagtcttta tttggagatt
    14881 tactgtttcc tttgattatt ttattttgtt tagtaattaa atggatcgag tggacaaaat
    14941 gggatcgcgg tatttatctg attgtcttta cggtcttcct cggaatcacg ttatatcgtg
    15001 tatttacaga gatccaagta ccagaaggac aaagcatctg ggctccaggc aattcgcttt
    15061 ctgatatttg gatcaatacg aatacaatcg gaagttcttt gatgactctt gctttattga
    15121 tcagtggatt tgccagttct tttgaacgat ggtatgtacg aatcatcggt gcagtagcag
    15181 ttgttgcagc ttttctcggg atttgggtct gccaatctag aggtgcatta gtcgcgttga
    15241 ttgtttttgc gatattggat cttttaccta aatcgttgat gcgtgtcatt cgtgcgccat
    15301 ttattgctta cacggttacg attcttttag ctttgccgat ttcttatctg gcggctgtct
    15361 ctgaaaaagt caatttgttt accggtcgag aagatatttg gcataaattc tatcagacgc
    15421 taggagaaaa atctgaacaa gttttactag gaatgaaaac atttatcttc caacgaggaa
    15481 accaattttt aggaaaccac aatagttata attctatttt gaatatctat ggattgatag
    15541 gatttgggat tgctactttg ctgcttatcc tttttattgg tcgcttaacg ttgaaagcag
    15601 atttatccaa cgggcagatg acttttatct gggccttttt tgcggtgatg atgcagtcat
    15661 ttatggagga tacattgact tcatacccat gggttccgat tatttatatc ctgttggcta
    15721 tggccgttca tcgatatgat gaaccagaag ttgcggagga attctatgtt atggaagagg
    15781 catatgacga tatgacttat gatgatacat cttatgagga acaaccagat agcgctcatt
    15841 cttccaggat ccaacgctat cattgatagg cacaaaa
//
LOCUS       DADVXM010000058        15755 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.061, whole genome shotgun sequence.
ACCESSION   DADVXM010000058 DADVXM010000000
VERSION     DADVXM010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.061"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(289..792)
                     /locus_tag="KB927_001931"
     CDS             complement(289..792)
                     /locus_tag="KB927_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBB6840847.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1151..2176
                     /locus_tag="KB927_001932"
     CDS             1151..2176
                     /locus_tag="KB927_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6840848.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2523..3401
                     /locus_tag="KB927_001933"
     CDS             2523..3401
                     /locus_tag="KB927_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBB6840849.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            3877..3993
                     /locus_tag="KB927_001934"
     CDS             3877..3993
                     /locus_tag="KB927_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBB6840850.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            4921..5259
                     /locus_tag="KB927_001935"
     CDS             4921..5259
                     /locus_tag="KB927_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840851.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            5353..5583
                     /locus_tag="KB927_001936"
     CDS             5353..5583
                     /locus_tag="KB927_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840852.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            5983..6354
                     /locus_tag="KB927_001937"
     CDS             5983..6354
                     /locus_tag="KB927_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBB6840853.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(6628..7320)
                     /locus_tag="KB927_001938"
     CDS             complement(6628..7320)
                     /locus_tag="KB927_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6840854.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(7323..8108)
                     /locus_tag="KB927_001939"
     CDS             complement(7323..8108)
                     /locus_tag="KB927_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6840855.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            8345..9745
                     /gene="lacG"
                     /locus_tag="KB927_001940"
     CDS             8345..9745
                     /gene="lacG"
                     /locus_tag="KB927_001940"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBB6840856.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            9770..10087
                     /locus_tag="KB927_001941"
     CDS             9770..10087
                     /locus_tag="KB927_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6840857.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            10100..11773
                     /locus_tag="KB927_001942"
     CDS             10100..11773
                     /locus_tag="KB927_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBB6840858.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            11787..13418
                     /locus_tag="KB927_001943"
     CDS             11787..13418
                     /locus_tag="KB927_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBB6840859.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            14290..15480
                     /locus_tag="KB927_001944"
     CDS             14290..15480
                     /locus_tag="KB927_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HBB6840860.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            15614..>15755
                     /locus_tag="KB927_001945"
     CDS             15614..>15755
                     /locus_tag="KB927_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6840861.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILL"
BASE COUNT         5004 a         2601 c         3219 g         4931 t
ORIGIN      
        1 agaaaaataa tatacctgag tagggtataa attaagacgg aattcctttc tagattgaga
       61 tattgactag gaagaatgtt aagattttaa gcctttaagc taaaaaaaaa ccctttttgt
      121 taaataaggg gaatatagcc tgtcagtttc aaactgcaag tcgtcctgct gcaataatat
      181 agtagattag agatgaaaat agattttttt aaaccaatga ctgaataaaa agaccgtcat
      241 agatacacat tggaatgtgt ctattacggt ctttttttac gaacgatttt attgaagacg
      301 gacagttcgg gtcaaaaata aaaaagctac gatcagaaat aagaataaaa tgtatcccaa
      361 aataatggct agacggtcta acttatttgt cgatagatgt ttgtttagaa gttgataggc
      421 ccataaacct atcagtcctc ctgttgtatt agttatcaaa tcagtgatgt ccgctacgcc
      481 aataccgaat aggaattgaa tcaattctgc caagaagctt acaaggaaaa taatccctaa
      541 ttttttagaa aaagaaagtc tcttgaaatt gacattcaaa agcaccccaa aaggaaaaaa
      601 gacaatcaag ttataagtgg tctcacgtaa taccgtcgta ttttcaaaag aaaaagtaga
      661 aaaagggacg agattgacat tgctgtaaga ataagtgaga aattgtggaa gattaaatga
      721 tagcttgaat aaaatcaacc ataatagaaa gaataaataa atccctaata aaaattttga
      781 tacataccgc atagacatct cctccattta aaaagtatac catcgaaaac cgctgaaaaa
      841 tcataaaaaa gtatgaagtt taaggaccaa cgtagttatc gtacgaaaat tagaagcttt
      901 tttttgttgg gaatccggtt tctttaacaa agctaagata gcgagttgct tggaaaagtt
      961 gctatctttt ttctgtcaaa acgactcgga atgttcgttt tttgttctaa tttctccaag
     1021 ttgtttactt tttgatacta agtttatgaa aaatcaagaa atagttgtta tactaggtaa
     1081 tgctgacaaa cgggattggc atttcatctt ggttcagctt tttttccaat tactaggaag
     1141 gagggataga ttgttcaaga cttattttcg tttcaataaa atacaagata atccttttcg
     1201 tatcatgaat ctgatgctac ttatctttat tgtattatgg ttaggttaca taaatcatga
     1261 ttttttgatt tcaagttttt catcattagg gatctttact tttttctatt atcaaaacat
     1321 accgatgaaa tatttgctga aacgtatgtt tctgatcggt tgcggactgt tggttgcttt
     1381 cgttttgggg atcttatcga cttatgtttt atggcttgaa ccatttgccg tagctttggt
     1441 tgctttttcc agcagattcg tgttgcgatt attccatatt tctaaaccag gtggcttgtt
     1501 ttttgcgatg ctttctgcca tgggaacgag catgcagctg ccaatcgctc aattaccgat
     1561 cgtctcactt tattttttta tgggtgtcgt ttttgccctg attgcggcag tgattacaaa
     1621 attactggat tcacggcctg agcagacaat tgaaaaagca actttaaaag aaagatttca
     1681 cgaagagcct ttagtgatca ttgattctgt tttctacagc gctgccttat ttctttccgt
     1741 ttatgtcagt cacggcttga atctgcataa tccttattgg ttgaccttgt catgtgcatc
     1801 gattttgcta gcagaaaact tggatgcgat gaagcatcga caagtccaat atctgattgg
     1861 atcgatgggt gggttatgtg tgtcggcatt cttgtcattt gtgccgttta cgcagttgca
     1921 gaccattttt ctgatcactt ttctatatgg aatcgcacaa tttctagttg ctagaaatta
     1981 tgcagttgct aatatttttc ttaatccgat ggcgttgatg ctatctacac ttattcgtgg
     2041 agcatacttg atttctttga tcgaatatcg ttttttaggg atcgtcatag gaagtttcat
     2101 cggtttaggt gttgcgtggg taatgacggt tggtttgcaa cattatttaa cggttgttcg
     2161 tcaaaaatta gaatagaagg acaaatatat gtgccaaaag aggttatgac aagatttttg
     2221 tcacaacctc taattcaagg tgttcaaaag ccagattctc agcattaagt caaattcaca
     2281 caaaaatgtg gaaaggaact ttcaaaaaaa ttttatattt attctatcaa aaaattttat
     2341 atttattcta tcaaaaaatt ttgtttatga tggtaactga ataaactttc ctgagatggt
     2401 caatgctttc cttgaaagtc ttacagatat tctttcttca tagaaagttt aagttttata
     2461 gttagtgtac aataaaagta tgtttatacc atatggtgtc cggataatca gtcatttaaa
     2521 caatgaggtt caaagatatg aaaaggggaa atttgatgaa gaaaataagc aatgaaatcc
     2581 aaattctggc agaaacttta actcttccca aagtcgttat agagcaaatg attgtacaag
     2641 caaaaaacat ccttgatgag gtgtttgagc aatatagtca tgaactaatg gatcctaata
     2701 aagcaaaggc gactgcaaag aaaatagaca aagtctatga agaggaacct tttgcagcat
     2761 tagctattta tctatatgca gcttctcaaa gttggaaaaa aatttatcaa ccattgaaga
     2821 ttccaagaac tatctatttg gcaacaatga atgcttttac tagatttatt catgaacatt
     2881 tccaagtaac aggaagctat cgctttgacc gtggtttttg gatttggcat tacactagtg
     2941 gcttgatctt tcggattggt gaattggagt acgaaatgac atattttccg aaagggtaca
     3001 cggatctaag attagaagga aagcagtgcc tttctcttca tattccttcc gatgcagatt
     3061 tatctcagaa taagataaga gatagttacg aaagtgccat tcgttttttt gaactttatt
     3121 ttcctgatta ccattaccaa gtgatgtaca cagatacttg gttactatca cccaatctta
     3181 ctaaatggtt gaaaaaagag tcaaaaatct gtctttttgc agccgattat cgattattat
     3241 cagttgatga acaggacgat agtggagtcc cttggatctt tggacgagta gatgcccaaa
     3301 tacatgatta tccagaaagt acgagtttac agcgacaagc aaaagagcaa ttgcttgcag
     3361 gcgagcacat tggctctggc ttaggtattc ttacttcata agtttagtac ttcgaaatag
     3421 tttaaaagag cgtgagacaa aagtaaagaa cacttttgtc tcacgctcta aacacgtata
     3481 aacggcggaa gcagaagcaa ctccttcgga aataagctga aattcacaaa aatttgaaaa
     3541 gcaattttcg tgaatttctt cttatttctt ggagttaaac gcttctgtcc cagcctcttt
     3601 tttagtgttc tatcgaacac acagtacgtt caataggtaa actagctata acaatagata
     3661 ttaaagttaa cggacaagag ggcctttttt aggtagctaa aacgtaataa tgaaaattta
     3721 tttccagaga taggagtcaa tcagctagtc tgatcgactg ttttaacaag ttgactttca
     3781 ttttaacttt tgataccatt taaaacacaa atcgtaattg tttcgatttg tgttttttag
     3841 catgactaca atcaaagaag aaagtgggtc gtccatatgg aaaaaacaga tatctcaagt
     3901 gcataccgcc gcttgaaaag cccaaatatc aaaacacgaa aacgtgcgct gaagatcatc
     3961 aaagatgtga aacggaatag tgggaaaagg taagaagaag gaaacttaat taaaaaaata
     4021 gccgaaaaac gtttttcggc tattttcaat aatcggtttt tgtgtaaggt ttccgaaaga
     4081 actgctgttg attttccatt tttaacatat gataaattgg tagaatcttt cttttcaaat
     4141 tgataccatt ccctaattcc agttatatag ttaactacag aaccacaaag cacgtacgtt
     4201 tataaaagta ttatctgtag ttatttttca attccctttc aacctcttat tttgaccagt
     4261 agtattgatc actttacctt ttaacacctt tgttcgtttt tgaaacattt ttagtcaaga
     4321 atggaaacgt aactacataa tcaaaggttt tgcgaaatat ttcatgaaat atttcatgta
     4381 gaagcgagca atacggttgc aaataaccat tatcgtttaa taagcagtta cgaaagctcc
     4441 caatatctct aacgttcagc tcactccatt tcttttcttc aaaaaaatca gtgattcgta
     4501 tctctttcta tttgtcgaaa aagttaactt taaaaagtaa cgccgaaaaa atatgcaaaa
     4561 aaataaaaaa gcagttacta ttgctagaat aacatcaagg aataataagt tttggttttc
     4621 agataatagt cgataagttg tgtattggaa ttttagatac agtaataaag tatttttcat
     4681 gaaattttgt gagaatcact attacaagta tctttaataa aattaatggt taaggaggaa
     4741 cttaaagtag aatgtaaatg aatagttgta gtcagtcgat tgtgatacta gactcaaagt
     4801 tgcaggaata agtttttcaa tttgtgattg gaagataaaa aatgaaaaag aagggctttt
     4861 ttttatactt tgttgattgt agtgtttatt ttccctctgt ttagccaagt aacattttct
     4921 atgactcaac cagtttcaag tgaggaacat gataaccttt ttcgtgctac agaagagttt
     4981 aagaaatatc aggaaaatat tgttccggag actccattag ctagtgagcc aattactgat
     5041 attgatggaa accaaatagg atggtatata cagtacgaag ttatggtggt aaataatgac
     5101 tcaatagtaa aaaatacagt aggcttagag ctaacaccga ttgaaaaggt gagttcattg
     5161 ttaacgtata tttatactga tgaaagtgac gagactgaga tcattttaac ggattactca
     5221 aaaattgcta ctgataaaaa gtatatattg tggatgtaga cactagtgaa atactttatg
     5281 atatagaaat tgatgaaaat ttactagatg tagcacaaga aatcgatcat caaaagcagg
     5341 aagctattcg atatgctggt agaaaaggga aaagaaaata tttattacgt gaatgtagca
     5401 aaagttagag aagatgaaaa tgagtggaaa gaattcaaga gtcgctactc aattaactcg
     5461 actccgacat ttacagttta cagagaagga tcgatagaaa aaactgtttt ttggactaaa
     5521 gaaagtggaa tgtctttagc tgaagtagaa gagtttttgg attatgttag tatgcaacag
     5581 taagggagtt cttattatga aaaattttga cacatattat gttattgttt tttcgatatc
     5641 tttgctgtta atattactaa ctttaatgca gtataaagag tatccagagt attttatttt
     5701 aacttttgta tatttagtaa gtagctacac acttctatat aaattcagaa gttcttctag
     5761 agtttctaaa gtttgtttct taattagctt attgattcta taatattttt gatttatata
     5821 ggaaattaaa aatattatag aatcaacact cagagaacgg gttggttttt aatagattta
     5881 ataagtactg ataatgaaat ttctcctggt tgggaaaacg aagttggtta ccctgtagaa
     5941 gaattttttc aagattactt tgcggagtat gccgatagga taatgagaga ttacgtaaca
     6001 gataaaactc aagaagtcat caatcaatcc cagtcattaa atgaattatc tgataaggcg
     6061 aaagaagaag cagttgccat tatttcttca gggattagtg actatattga tatgagtggt
     6121 gaaatcaatt atggcgataa agacaaaatt gtacgcatga taaaagcttt tatcaaaact
     6181 tttgatgtga aggcagatct taagtttaat gatacttacc tagtaggaaa attaattaat
     6241 atccttggga cagagaaaga tacggaaacg tttatttcct ctttgtctat gttgtttaca
     6301 gataagcatt tttcaactca gcttggtgga gaggaactag tggaaatctt ttaaccatta
     6361 cgcccagcat taataaaagt atatcaaaaa agtactcctg atgattttta agattggttt
     6421 gagaaataat gtgaaaacac tatttttaat gttaattata gatagagatg aacgcgtcat
     6481 atggttaaaa gaatgaaaaa gtcaaagata cactgctata tttcactaag gatatagcag
     6541 tgtatctttc atgtcgtttc actggcagtt ttttataaaa ggaggtgtgc atttcagttg
     6601 cttttctttg gtagttagtt gaatcgttta agaattaacg gatgtggcag acaggtgctc
     6661 tgtccaaaaa ccagtaaaat ctttgatggt tccatcttta tttagctgtg cctgttcaaa
     6721 tactgttttg tttttaccga atggatcaat tgcaataatt gttccgatcc ccgcacgttt
     6781 ggcagcaagt aatcctgagt aagcatcttc gataacaaga caatcagccg gagctaagct
     6841 cagtttgtct gccgctttaa gaaaaatatc cggttgcggt ttcccaggga aagagccgtc
     6901 gtcatagaca atcttgtccc agtcaaacca gcgggctaaa tcgaaaatat caaaataaaa
     6961 agcaacattc tctttgacag tagccgtggc aatcgttaat ggaatctgtt ggtcagtcag
     7021 ctggtcaaga gtcgcttcaa gcccttttgt caactgaagc tcgttttcat tttgcaagca
     7081 aagcatacga taatagcttt ctttttcttc tgacaatacg gcgatctcag aggcggtcaa
     7141 atgctctgaa atgaaatgtt tcaaaatctc cgtattcgtc cgaccatgaa tattttttaa
     7201 aatatcctcg tctgataaac catcttttgt atgatcatgt atcatatgca gccaagcagc
     7261 ttcatgcaga tgagagtcca aaaacattgt tccgttgaaa tcaaatataa tccctttcat
     7321 agttacgctc ctatagtggt attttcggtt gaatcagcaa tttgcagatc gacatattgt
     7381 gcatagtgct cttgaacctc ccgcgagatc tggcgatccg taatgagcag atcgaaatca
     7441 tgcaaattat aaaacacata aaaatcatct cgattgaatt ttttattatc aacgagtaga
     7501 tatttcttac gggaattatt tagagcgatc tgctgtgctt ctccttcttc ggtactgtaa
     7561 gtagagatcg cttcgttgtg aacgccattt gaactgataa atgcttttgt aaactttagt
     7621 cttcttaaat tgtcgttggt gatcggtccg acaaatgcgc cggtattttt ccggaaatca
     7681 ccgccaatca gtagaatttc tggtccatct gcttgagcaa gaatatcaaa aactggataa
     7741 ttatttgtaa tgatccgaat tttcttgttc agtaaatgcg tcgccaatag ttcgattgtt
     7801 gtacctggtc ctaagaaaat cgtttctccc tcgtgaatca aggaggctgc tgtggcagca
     7861 atttcttttt tttcttgaat ctgcagagtg gctttttcag tgtgagaaag ttcttgatct
     7921 aaagtgtagg aaagactttg agcccctcca tggacacgca gcagcttgcc cgatttttct
     7981 aattcatcta aatctctgcg aacggtcata tcagaaacat ctaattgatt gatgatttca
     8041 ttaacggtaa ggattccttt tttattgacc atttctacga tagtaagcaa tctttctttt
     8101 ttcaacattg tcttcacctc taatttaagg ataatctatc atataaacgg acaacagtca
     8161 atctaattcg aacaaaagta aacatttagg gtggttttta tgtttgttac aatagatttt
     8221 attgctgttt tctggttttt atgattattt gtgtttgttt ttgttgacaa atgttttgga
     8281 tgcgtttaca atgcaatcag ttagaaagag cgaaaactga ttatagattt gaggagagat
     8341 gtacatgctt aaattaccag aagattttat ttttggcgga gccacagcag cctatcaggt
     8401 tgaaggagcc actaaggaag gtggcaaagg cgctgttgct tgggatgact ttttagagga
     8461 acaagggcga ttcagtcccg atccggcaag tgatttttat catcaatatg caaaggacat
     8521 tgaattgtgt gaacgttttg gtgtaaatgg tctaagatta tccattgctt ggagccgcat
     8581 ttttcctgat ggagctggga aaccaaatcc agaaggaatc gctttttatc atcgtgtgtt
     8641 cgaagaatgt aagaaaagaa acgtaacgcc gtttgtgacg ttgcatcatt ttgatacccc
     8701 taaacgtttg tttgaccatg gagatttttt gaatcgagaa acaatagaag catttgtttc
     8761 ctatgccatt ttttgttttc atgaattcaa agaagtcaag gtgtggagta cctttaatga
     8821 aatctatcca gttgcaacca atcaatattt gttaggtgtt ttcccaccag gaatcaaata
     8881 tgattttaca aagatcgtcg cctgtcttca taatatgatg gttgctcatg cccgtgtagt
     8941 gaactatttc aaagaaaacg aacttccggg tgaaattggt gtagttcact cattagagac
     9001 gaaatatgcg gcaacagacg cgccggaaga taagcatgct gcctttttag acgatgcatt
     9061 gtcgatccgt ttcttattag atgctaccta tttaggctat tattcaactg aaaccttgac
     9121 tgctcttgat gagatatgtg aagcaaatca ggccagctat cattttcctg aagaagattt
     9181 cgttgaattg aaaaaagcat ccacgcgtaa tgactactta gggatcaatc actaccaatg
     9241 ccattttgtc aaagcttacg atggagaaaa tgcaatccat cataacggta cgggtgaaaa
     9301 agggacctct gtttataaag tgaagggaat cggagaacgt atttataaag aaggaattcc
     9361 tcgaactgat tgggactggc tgatttatcc agaaggtcta tatgacttgt tgctgcgaat
     9421 taaaagcgat tacccacatt acaacaaaat ctatatcact gagaacggga tggggtataa
     9481 agatcagttt gaagatggca ttattatgga tcagccgaga atcgactatt tgagagtcta
     9541 tttggaatcc ttaagcaagg cgataacagc cggggtaaat gtgaaggggt attttttgtg
     9601 gtcgcttatg gatcttttct catggacaaa tgggtataac aaaaggtatg gcttgtttta
     9661 tgttgatttt gaaacccaga agcgttaccc aaaagaatca gcttactggt acaagttggt
     9721 cagtgaaacc aaaacgatta tttaataagt gataatggag gaagaaaaga tgaataaaga
     9781 ggaattacaa atgcttggtt ttgagatcgt tgcatattca ggcgacgctc gcagtacatt
     9841 attgaaatta ttgaaagaag taagacaagg aaactttgaa catgttgatt cggcgttgaa
     9901 agaagccgac gaaaatttaa cccttgcaca taattcgcaa acaaaaattt tagcggaaga
     9961 agcatctggg aaagagatgg agatgggatt catttttatc catgggcagg atcatttaat
    10021 gaccacttta ttgctgagag atctgattca agactttatt gtactgtaca gacagaatca
    10081 aggataggag aagaacgcta tggatggaat cattaaacaa atcgaaaaag ggaaaccatt
    10141 ttttgaaaaa atctcacgta atagttattt aggagccgtt cgtgacggat ttttaacagc
    10201 gatgccagct attttatttt caagcatttt cattttgatt gctgcggttc ctgagatttt
    10261 tggttaccaa tggcctgaat ctgtctccac atggctatgg aaagtctata attattcgat
    10321 gggtgttgta gggttactcg tttcagcaac cactgctcgc tgcttggctg attcgatgaa
    10381 tcgtcgctta ccgaaaaaca aagtaatcaa caccacctct gtgatgctgg cctctgtggt
    10441 aagtttcctg ttgttaagcg tctctccgat tgaaggtgga ttttcaacgg aatatatggg
    10501 gacaaaggga ctactggctt cctttgtcgc tgcattttta acagttaatt tatataagtt
    10561 ttgtgtgctg aaagatatta ccattaaaat gcctaaagaa gttcctggaa cgatttcgca
    10621 aaccttccga gatatttttc ctttctcttt ttcagtattt gcggccgttt taattgattt
    10681 aggcattcga caaatcttcc aaatctcatt tgcagaagca atcattacgg tgctgcagcc
    10741 gctatttaca gcagctgacg ggtacttagg aatcgctatt atctggggag cgatggcgct
    10801 gttttggttt gtcggtgttc atggaccgtc gatcgtggag ccggcaattg cggcaattat
    10861 ctatgccaat gtggaaacca atctgcaatt gttcaattcc ggtgaacaag cttctaaagt
    10921 actgacggtg ggtttaggga attttgtagg aactatggga ggaactgggg caacattggt
    10981 tgttcctttt atcttcctac tctttgctaa gtctaagcag ttgaaggcag ttgggaaagc
    11041 ttcctttatt ccagtaagtt tcgctgtcaa cgaaccattg ctatttgcgg cacccatgat
    11101 tttgaaccct tattttttta ttccattttt gttaacacct gttgtaaacg tttgcctgtt
    11161 caagtttttt gtcgatgtat tgggcatgaa cagctttatg tacgttttgc cttgggcaac
    11221 tccagcaccg atcggtttgg ttctaggaac gggcatgggt atcttagctt ttgttctagc
    11281 agcggttcta atcgtcgttg acttcctgat ctatctacca ttttgcaaag catacgatgc
    11341 tgtcttagta gagaaagaag cacaaaaagc agaggtgatc gcaaccgagg aaggtgcttc
    11401 tgccgatgta cgtgaggaag tacctgtggc agcgagtcaa gttatcagcg atgcaaataa
    11461 agaaatcaat gtgttggtac tttgtgctgg cgcagggaca agtgcgatgt tagctaatgc
    11521 tttaaaaaaa ggtgcatctg aatcgaaagc accgatcagt gcaatggcgg gtgcttatgg
    11581 ttctcattac gaaatgctgc aggattttga tatggtggtc ttagcaccgc aagtcaattc
    11641 ttactatgat gatatcaaag aagacaccga tcgcttagga atcaagctgg ttgcgacaaa
    11701 aggagcagaa tatatcggat taacgagaga tcctgaaaaa gctgttcagt ttattctgaa
    11761 ccaatttcaa taaaggagga gccataatga aaatgggaat ttggttgcgt aaagctgttt
    11821 tatttgcagc tgtgttaggg gctttggggg ctgtttcaaa aactgttgaa gcatctgcca
    11881 gcgaatttat tcgcggagca gatatttcga tcctgtcaga tatggaaaaa tctggtgcaa
    11941 aatattatga agacgatatt tcaaaagatg ccttagagat tttaaaaaat aatggtgtca
    12001 actatgttcg actgcgtttg tggcaggatc cttataatag taatggagaa agttatggag
    12061 cagggacaaa tgatctggaa acgacgattg accttgcaaa acgagcaaaa aatctgggac
    12121 ttaaggtgct gctggatttt cactacagtg atttttgggt tgatcctggg aaacagaatc
    12181 ttcctaaagc atggcaaggt ctgacctttg aagaaatgaa tacggcattg tacgactata
    12241 caaagaacgt tctgtcggaa atgaagcagc tggacgttta tcctgatatg gttcagatcg
    12301 gcaatgaact gaatagcgga atgctctggc cttatggcaa gtcttgggga gaaggcgggg
    12361 gagaatttga tcgattggct gcttttttga agtctggtat ccaagctgtt cgagacactc
    12421 aacctaaaac aactccagta atgctccact tagctgatgg tggcgataca ggagcattta
    12481 cttggtggtt tgatgaaatc acgagtcgag gtgtgtcatt tgatttaatt ggagtgtcgt
    12541 attatccgta ttggcacggt tcaatgaatg aacttcaaac caatatgaat gcgatcagcc
    12601 aacggtatgg taaagaagtg atcgtagttg aaacagctta tgggcataca acagcgaatg
    12661 ccgatactat gccaaatgct tttggtgaag ccgaagcagc tgcgggggga tatgaaccaa
    12721 caccgacagg acaagcagag tatttgctgg atcttgccga tcggattcag gcagtaccga
    12781 ataatcgcgg ggcgggcttc ttctattggg aacctctttg gtacaacgga aatgtgagtt
    12841 gggcaacaca agcaggtatg aattatctca gtgttcaatc cactatggga aacgaatggg
    12901 acaaccaagc gatgtttgat tttgctggaa acgccttgcc aagcttgcgt gcgtttaaac
    12961 aagcaggggc gcaaataaat ctagttaaaa atgcaagttt cgaaagcgat ggaccaacga
    13021 ccagtccttc caattggcaa acctggtttc aacaaggaac cgctaagggt acgatcaaaa
    13081 cggaagcggg cacttttttt ggggactaca aactaacttt ttggcaggat caagcatacg
    13141 aggcatcagc ttatcaaaat gttagtggca taagcaaagg aacttacaca ttgagtgcct
    13201 atgtaatgtc tgggggagag tttgatacta atcagttata tatcaaaaat tatggtggag
    13261 cggaactaaa tactgcggtt gttaaaacaa gtgaatggac aaaaattaca atcaaagaca
    13321 ttccaattac aacaggtgtt tgtgaaattg gggtttatag caaggcttca ggaaatgctt
    13381 ggacgaacgt tgattttgtt tcattggtga aacaatagac tgcggatcgt ttcgattcaa
    13441 gatcggaggt tcccttcagc cacatcgtta gcgtagaagg caggaatcga acctgcacct
    13501 cgcctttgcc aaaaataacc agaaacgatt tccagtcatt tttaccaaaa cgagtaaagc
    13561 accagacttc atctacactt tgtattatgc taaagagagt tcaacgattt cgtaagaagc
    13621 aatgaaaaaa ttgcaaaaag ttgtgcagat aacataaagt ttgtttaaga aagggtaacc
    13681 ttagaattcc gtcgtgaata tgatttgagc acttagatgg atagaaaaaa gttctcggaa
    13741 aacagttcgt ttttcgagaa cttcttttta tgataagaat gaaacaaatt aacttatatt
    13801 atagtctctt ttggtaggga accatcttat ttttaatgaa aatcaagcat tttagctatt
    13861 gaagaatgtt gatttatagg gattccccct ccatattatg ttggctcttt attcccactc
    13921 tgttttcaac gtaaagtgta taaaacagaa tgcgatacta tcaagggagt taaaacaata
    13981 tacagaacag taaaacacta taaataaaaa taaaagtgca ataaaagtgc aatttttgca
    14041 cctaatcata ctctgtttat atatgaaaac tagattctga atccaatatt tggttaacga
    14101 gaggcgttcg aatttgaacg tcttttatat attactttca aataaatatg aggtagaata
    14161 ctatctattt tctttttaac ccaattgtta taatggagag tgtaaaatat tttgtgtaaa
    14221 tagaaaaaag gaagtccctt ctgtagaata gagttaccac aacacattca cagaagagag
    14281 gacttcccta tgaacgattt tactacagaa attctaaaga ctctagcgaa caaaggcgat
    14341 ttgaatgaat tattccgtgt ccatttggag aaagcagtca atacgcttct caaaacggag
    14401 ttaacggctt tcctagatta cgaaaagtat gatcgcattg gttttaacac gggtaattct
    14461 cgtaacggct cctatgaccg tacggtcaag accgagtatg gggaacttca tctccagatt
    14521 ccgcgcgacc gcaatggtga gttcaagcaa cagactgttc ctgcttatag acggacgaat
    14581 gacacgttag aggagaccgt cattcacctc ttccgaaaag gtattaccat gtcggaaatc
    14641 gcagacttga ttgagaaaat gtatgggcat tactacacgc cccaaaccat gtccaatata
    14701 acaaaatcat ttacagaaga ggtaacggcg tttaatgggc gggagcttca tgaccgttat
    14761 gctgctattt atatggacgc aacgtatatt ccgttaaagc ggaaaaccgt cgccaaggaa
    14821 gctattcata tcgcagttgg cattcgcccg gacggatcaa aggaagtatt gagctatgcg
    14881 attgcaccga ctgaatccat cacgatttgg gaggaaattt tattggacct tcaagagcgc
    14941 ggtttgaaaa atgtcctcct gttcatcacg gatggcttaa aggggatggt aggagcgatt
    15001 agtcggttct atcccaaagc tcgttttcaa cattgttgtg tacacgtttc ccgtaatatc
    15061 agtcataaag tgcgtgtcga tgatcgtaag gaagtctgtg atgattttaa aatggtgtat
    15121 caagcctcat ctaaagaggt ggcgttggaa gcacgtggta cttttgcgga aaaatggaaa
    15181 accagctatc caaaagtggt tgaatcgatt ctttcgaacg atcacttgct cactttctat
    15241 gatttcccct tggccatacg caagagtatt tattctacga acttgattga atcctttaat
    15301 aaacaaatca agaaatacag ccaccgcaag gaacagttcc aaaatgaaga gtcgatggaa
    15361 cgtttcttag tctcgtcttt tgatacttac aaccaaaaat tcctaggtcg cagtcataaa
    15421 ggtttccaac aggccgaagg cgagctcgaa caaatgctaa gccaactgat tgagaattag
    15481 aaacaatctg cagtagggaa gaatcattta cacaaaatta ttgacgctcc cttataatga
    15541 gaacttttac taacataatt tatgataaac ttactatata atcatattaa ttaaatagtt
    15601 aggagatctg cttatgttta tatctactct tcaaattcga aattttagaa attatgaatc
    15661 cgaaatcttt cgattcgata atgagacaaa tactattata ggtgagaatg attcagggaa
    15721 aaccaatgct cttactgcat tgagaatctt attag
//
LOCUS       DADVXM010000059        15474 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.062, whole genome shotgun sequence.
ACCESSION   DADVXM010000059 DADVXM010000000
VERSION     DADVXM010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15474
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.062"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(369..1487)
                     /locus_tag="KB927_001946"
     CDS             complement(369..1487)
                     /locus_tag="KB927_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840862.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1958..3265
                     /locus_tag="KB927_001947"
     CDS             1958..3265
                     /locus_tag="KB927_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBB6840863.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3384..4583
                     /locus_tag="KB927_001948"
     CDS             3384..4583
                     /locus_tag="KB927_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBB6840864.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4610..5878)
                     /locus_tag="KB927_001949"
     CDS             complement(4610..5878)
                     /locus_tag="KB927_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBB6840865.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(6041..6687)
                     /locus_tag="KB927_001950"
                     /pseudo
     CDS             complement(6041..6687)
                     /locus_tag="KB927_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(7095..7598)
                     /locus_tag="KB927_001951"
     CDS             complement(7095..7598)
                     /locus_tag="KB927_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6840866.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(7721..8485)
                     /locus_tag="KB927_001952"
     CDS             complement(7721..8485)
                     /locus_tag="KB927_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBB6840867.1"
                     /translation="MKEIQSVKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSSTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            8592..8867
                     /locus_tag="KB927_001953"
     CDS             8592..8867
                     /locus_tag="KB927_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBB6840868.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            9583..10536
                     /gene="yidC"
                     /locus_tag="KB927_001954"
     CDS             9583..10536
                     /gene="yidC"
                     /locus_tag="KB927_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBB6840869.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGGAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAAKPADNKQATKQIKQPKNSTNNKGRNAGRQQKRK"
     gene            10640..11867
                     /locus_tag="KB927_001955"
                     /pseudo
     CDS             10640..11867
                     /locus_tag="KB927_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(12177..12398)
                     /locus_tag="KB927_001956"
     CDS             complement(12177..12398)
                     /locus_tag="KB927_001956"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6840870.1"
                     /translation="MFKNYTINQKILPLDMEQYISETDVAFAVNALVEEKIKVDLYVS
                     SKFTNVKVVGADLFVVNVRKQKVSETDKF"
     gene            complement(12559..12957)
                     /gene="tnpA"
                     /locus_tag="KB927_001957"
                     /pseudo
     CDS             complement(12559..12957)
                     /gene="tnpA"
                     /locus_tag="KB927_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003513861.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(13171..13537)
                     /locus_tag="KB927_001958"
                     /pseudo
     CDS             complement(13171..13537)
                     /locus_tag="KB927_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
     gene            complement(13551..13836)
                     /locus_tag="KB927_001959"
                     /pseudo
     CDS             complement(13551..13836)
                     /locus_tag="KB927_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
     gene            complement(13842..14036)
                     /locus_tag="KB927_001960"
     CDS             complement(13842..14036)
                     /locus_tag="KB927_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840871.1"
                     /translation="MAETRPKGYPKLKEYTPSRFMLSECHYDKARADRAVNFIGQLRH
                     TKGKWAGNRFWLLPWQEQII"
     gene            complement(14036..14512)
                     /locus_tag="KB927_001961"
                     /pseudo
     CDS             complement(14036..14512)
                     /locus_tag="KB927_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290865.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
     gene            complement(14980..15333)
                     /locus_tag="KB927_001962"
     CDS             complement(14980..15333)
                     /locus_tag="KB927_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840872.1"
                     /translation="MAMSEKAKKYLKEIKGAKTIPELKDVEIAIKRDGILAWAEFTKL
                     NEAVEEKKVALRKKKQETSLQEILFWAYKKESDKLLKMMDEGADKDAIQMQVQRYDSI
                     GQIIAEADLEDEYEV"
BASE COUNT         4557 a         3264 c         2783 g         4870 t
ORIGIN      
        1 ttttttaaac ggtgttccag aagtagcttc ttcggaaata agccgaaatt tcacaaaaat
       61 ttgagaaata atttttgtca atctcttctt atttcttgaa gctgaccact tctgtcacaa
      121 cctcttcctt aaacggtgtt caaaagcttg catctgcggt aataagccca ccaaacaaaa
      181 aatatgaaga gctatttttg cttgctgttc ttattacttg atgcagaaca gctttttcac
      241 aacctctcat acacggtgtt taatcagctg accttcggta ttagctcaaa aaacggaaaa
      301 atatgtgaaa ctatttttcc gtttgtttct ctaatactca ggtcaaaaca ctgatttcac
      361 aacctctttt aataacgaag aatcgctgtc agactctttt catctggcgc atctttttga
      421 tccaaaataa acactttccc gccattaatg atcacatcat ctgctaatgc attcaacact
      481 tgacgccgat catattctgt ttcaggatct tcaccgaaac catcagctaa gtttgacgta
      541 gcgataaata aatgtgacac ttttccttct ttcgcagctg gaacgatatc aactaactga
      601 tcgatgaatt tcttatctaa gagtttattg tattcttttg attcttgagc tgcgagttca
      661 cttgacagct tcttcgcccc ttcttcgata tctctaaagg atagctgcgc aggagaagca
      721 gaaatcgcaa cgtctgcaca ataataggga tttttagcaa tttttttgaa catcgtctga
      781 ttttctggta atgcaaataa ataaatcggc cattgttcag gattttcgaa agaatccttc
      841 aagtacgtat caacagcttg gtaatagttg acccaatcga tctctacttc ttcatctttt
      901 ggatttacgc catggaaagt tactccatct cgggctccgc ctcctccatt agaagagaag
      961 ttcaaaccgc cacctgtcag ttcagatccc aatgcagtaa cgacatcaac cggtgcccct
     1021 tctggtagag atacttcttt tacttgtttg ttgctgacct catacaattt catggagtcg
     1081 cggttcaatc ccaataaata ataagaatag ttgaactgcc catttttgat aatagccagt
     1141 aaataaggaa gatcacttac atagtattga tcgtctaccg ggatactcaa acgatggata
     1201 taggtctggt cagcagttat aatgaccgct acactcgtag ttgcactacg ccaaaacgaa
     1261 ggatctccta acaaattttc aattttttct tggaacgggg accagtcatg ttcggaatat
     1321 tttttctcaa aacgtttctt tgcttctttc gcaaaatttt tgaatttgat ctgatctttt
     1381 tccacatctt gatgggcgac atgcgtattc agcatgatcg tgacgaatgg tcctttagcg
     1441 ccttctgaag tcaattgtgt caataattct ttatcctttt ttgccataaa cgtacccctc
     1501 ctaaaaaaat cattcctttg tttctatcta aagtctacca caacactatt tttccataca
     1561 ataaaacgta tctaaaaaaa taaaacggtt tctacggttt taaatttagc tattttttta
     1621 agttatcttc ataatttcct caattattta gccccagtct tcaactattc ttcatgaaat
     1681 gctgataaac taagaaaaag aataaaagag gtggatctta tgcatttgat tatgattttc
     1741 agtttattaa gtattatcag tttatttgct ttcagcgctt cccgcttatt agatgcggaa
     1801 acacagccta ttcctgtaaa agtacgtaaa aacgaccgct aaacttccat aacgcgcgtt
     1861 cttatcctaa agttttttca gaaacattga aactctctcc cctctctgat aaaattttaa
     1921 tttgtagcga aacaaattaa ttacaaggag atcggatatg tccataaaaa aaacacgtct
     1981 agtcctatta ttggctagtc tcattctttg ccttgcttct tttctaccag ctgttgctgt
     2041 gcaagctgaa gatacgttca aagtaaatgc aaaagcagct tttgctgtag atgcgcaaag
     2101 cggtaagatt ctttatgatc aagatggaga aaaaaccatg gggatcgctt caatcacaaa
     2161 aatcatcggt ctttacatcg tccttgatca agtaaaagaa ggaaaactgt catggggtga
     2221 taaagtttcg atttcagatt atgcagaaaa tttgagtatc accccagatt tatcgaatgt
     2281 tcctttgcat aaagaaaaca cctacactgt caaagaatta ttcgactctg caatcatcca
     2341 gtcagccaat gcttcaatgg tggccttggc agaaaaaatc tctggcagcg aagctaaatt
     2401 cactgaacga atgaaagaac aattgaaaga ttggggaatc aaagatgcaa caatcgttaa
     2461 tgcatcagga ttgaacaact cttatcttgg cgaaaaccga ccagaaggca ctggagaaaa
     2521 cgacgaaaat caaatgtctg ctcaagatgt ggccatcgtt gcccgccatt tgatcttgga
     2581 tttcccagaa atactggatg tatcaagtac tacgacccaa atgtttggcg aaaatacgca
     2641 atcaccagtg gaaatggtca actggaactg gatgctccca ggattcgtta attacaagga
     2701 aggcgtggac ggattaaaaa ctggtacgac tgagcttgca ggtgcttgtt tcgttggtac
     2761 gatcactaaa aacgatcaac ggatcatcac tgtcgtattg aatgcggacg gccatgcgga
     2821 aaacccgagt gcccgcttca atgaaacaga ccgtttgatg gactactgct atgacaattg
     2881 gtcagaaaaa gagctcggaa aagctaacgc aagtattcct agtctaaaaa ccattgatgt
     2941 aaaagacgga aaagaatcaa cagttcctgt tgtgcttaaa agccctgtaa aagtatgggt
     3001 acgaaacgat atggatactg gcaaattaac gatcacgcca acacttgaca agaagcaagt
     3061 cactgacaat gagatccaag cacctatgga taaaggtaca aaaatcggta ccgctacgat
     3121 caccttggca gacgataaat taggctattt agaagacaac aatgcaccat caacagagat
     3181 cattacggat aaaacagtgg aaaaagcgaa tatattcgtg attggctggc gacgcgtcgc
     3241 agaatttttc ggcaacttgt tttaattgaa caataagaaa aacatctttc catcggaaag
     3301 atgttttttt gctttttcta gtttaaataa cagctttttt catctatttt cgttatactg
     3361 tataagaaaa aggagttgaa tttatgaatc taaccagaga tctgatcttt ttagttctct
     3421 atcttattgg ggtattctct atcgtttatt ggcgaaaaca gaagaaggat ccttccttgt
     3481 tcttttacgg cagtacgtgg acatttacgg taatcttaac ttattttgtc gtgttggaaa
     3541 ttttttattc gaccttttat tttttgattc cattgttgtt ctttagtatc tttgcttttt
     3601 cttatttcac agaaaaacga aggctactga atggtctttt attcaatgtt ttactcatca
     3661 gtttcggcat ctacttgttt gtcttgctgt atgaaacgca aaatattttt cttggcggac
     3721 tgatcgcctt gatcacgatt ccattgctac ttgtcctttt atttggtatt tatggattga
     3781 ttgtttttct tttttggaac ggggtcacag ttttacgtag agaatcgcat tcattagcta
     3841 atcttttaac gttgatacta gccatttttc ttacactgtt tcttgttttt gactttttct
     3901 tgttaaaata tttgccgcaa tggataaatg ctttgttttt ctgcgttccc ctgatcttga
     3961 tctatctatt tatcgtattc tacaactttt tgactgtctc attcttgtat cagttcaacc
     4021 ggcctcgata caatcaagac ttcatcgttg tgttaggcgc tggattgatc aatggagaaa
     4081 cagtttctcc tcttctagcc aagcgaatca ataaggcaat tgctttttat cgggctcaaa
     4141 gccgtgctac attaaatccg cccatcttat tgatgtctgg cgggcaagga gcagacgaaa
     4201 aagtaccaga ggccattgcg atgaaacaat atgccatgga acaaggaatc cctgaaagag
     4261 acattcttgt cgaaaccaat tcgacaacca ctttggaaaa catgctctat tcaaaggaaa
     4321 tcatggatca gcaaatgaaa gggccatacc gcgcgatctt tagttccaac aattaccaca
     4381 tttttagagc cggtctttat gcgcggcaag ccaaattgaa agcaaatggt attggtgcaa
     4441 aaacagcttt ctactacttg cctaatgcgt ttttaagaga atacctcgcc atcttgatga
     4501 tgaacaaaaa aagacatatg atcatttgcg gattgctttt cgcaggctcc gcattcttat
     4561 cgctgattac tttacttttc taaaaaaaca aggtgtgaca aaacatatgt cacaccttgt
     4621 ttttttcttt cattctctta actattggca aaaagagtat cccttttttg accgctactt
     4681 gctgagcaga ataaataccg ctgttgcctg aacacataaa gctgatcaag cagatcataa
     4741 agaagtatac tgccgcttgt gaaccgaaca attcgatccc catcacaaag caggcaatcg
     4801 gtgtatttgt cgcaccagaa aatactccga taaagcccaa tcctgcaaga aaaggaacag
     4861 aaacatggag caaaggcgct agtgctgcac caagcgttgc accaatttca aacaatggtg
     4921 tcacttctcc cccttgatat cccgcgccta aagacaaaac tgtgaagaat aacttcccaa
     4981 taaaatcata gacatgtgcc tgtccattaa atgattcttg aagtaacgga agactcaatc
     5041 cgagataacg ttgtgtttgc aaaatcaatg ctgctgccac aactacagct ccacctatcg
     5101 tatttcgaca aacaggatga ggaatccatt gtgcatatcg cgcttttaaa aagacgatcg
     5161 aacggctgaa tacccaacca atcaaaccaa aagcaatccc agcaacaaaa actttgaaga
     5221 acagcaacat actccattca ggaatcacac ccatttggta atgtagatga gaaacaccat
     5281 agctttctgt catgaaattt gcaaacagtg cagcaaagaa gctagggaag atcgcttctg
     5341 ttcggacttt cccgattgcc aacacttcta atccaaataa tgttccagct aaaggtgtgc
     5401 caaatacaga actaaaaccc gcactgattc cactgataat caagatttcc cgttctgatt
     5461 tatccaatcg gaacaaacgt gccgtattat ctgctaacgc tccccccatt tggactgctg
     5521 ttccttcacg gccaacagat cccccaaata aatgggtagt tatggttcca aacagtgtaa
     5581 gtggaataag ccgcaacggg attttttctt ctccaccatt tccttgatcg atcactaagt
     5641 tgtttccacg actagaaagt ccgccgtgat acgcatagag ataagcaaaa agcgcaccac
     5701 taactggtag tagacaaagg agccaaggat gtgatagtcg gatatctgtc acaactgtca
     5761 ggctatttaa gaaaaaagca gacaagctcc ccatgaatat accgagaatc gctgtgatca
     5821 ccagccactt cagcatatac actaaaatgc gtactggact cggtaattgt ttttccataa
     5881 aaaattcctc ctcaataaaa aaacgcctac taaagaaagg ggctgtcccc agactttagt
     5941 aggcgtcatt agctatcttt cgttagcatt taaaggcgaa caccatcacc tattcacttc
     6001 cattaaaaga tagcatattt ttctgtaaaa aacaataaaa ttatcgttct ttctttacac
     6061 gttcagcaaa ttcatagaaa ggagccaatt tcgttaactg ttgattacat tggtcactat
     6121 catgacaaat ataattcccc tttttcgtat acgtgccatc agaacctgct ttcgttgtag
     6181 aaagaaaaag cgaaacattc gatgttttct gacagattgc acagattccc ttatttatcg
     6241 ttggtgataa agtaccgcta atccctttta atttttcatc ttcgtaatag accatgaatt
     6301 ttttctgcgt acctggatca ttccagccga tgtacgtatg ttcttgcaag tcgatttcat
     6361 tccaagctgg ttgtttgagt tttttcactt ttcggaataa tttctcgatt tgtggtttgc
     6421 taggctgcat aaacggctga acgatttgct tcagctcctc caatgctctt tctgcttgcg
     6481 cttttgtcag ttttacgtct aaaactgtcg ttaaaaatgt atcgattctg gcagttcgtg
     6541 atctaatatg tctcgaatct tttcagctgc tagtgcctga actgtttgta ccgtttttgg
     6601 atcattgaca gatgagtacg catttaataa ctgttctact tctcttatta taaaaaaata
     6661 ttggtatggt tttattgttt gttccatgat tttaaagtcc tttcttctaa ccaaagtgca
     6721 tactttgtag aaaaaagtga tcttctgcaa agtatgtgtt acctgaagat cctggactct
     6781 tttaaataag atacgttttg catcttatca tcaccccctt taatgcttat tattctatgt
     6841 acatgattca ttcgataaat aaaagtaaac cgtatcttga acagatagtc aactgcaaac
     6901 agaaaaaagg actgtgacaa aagtcgtgtc aaagtccctt gtttcgaatg aatggtgttc
     6961 aaaagcttgc atctgcggta ataagccgaa acttcacaaa aatttgagaa gtaattttcg
     7021 taaattcctt cttatttctt gaagctgacc acttctgtca caacctcaat atggtctatt
     7081 attggtttta cctgttaaat cgaggattct ttcccaaagt aacgttgcca tctcttacgc
     7141 atacttgcag acatgggctg agccgcttct ttgactgcgc agtatttgtc cacgaatgtc
     7201 acaatatatc cttctttata cttaggcggt gcgatcgttg caccccacat gtgcttcaaa
     7261 atgatatctc gctcaagatc cgacaaatcg gtgatttttt ctgcattctt tacagcaatt
     7321 cttggatgga tatacgcatg tgtcccctcg tcaaatttcg tcgtacgcca atcatagtag
     7381 aacagatcat gcaaaagtcc agcacgcgct gttgctttag cattgccacc ccattttttt
     7441 gcgagcagat aactatagta agaaacactg atggaatgct ccaaacgagt ggaatgaaca
     7501 tgctgtgtgt aattcgctaa ttttttcact gcttctgttt ctaaaagatc ttgtacataa
     7561 gacatatatt cttcgtcttc acgccatttt tctgtcataa ttatcgattt gccacctttt
     7621 tgaatttcat tttcttctga aattgatcta agtataccac cagtgttcgg attattctag
     7681 tcgctctaga taaaatagct aaagcttaat agttccttaa tcataaagaa aaatgataaa
     7741 gaacgatccc tgctgcgact ccgacattca atgattccgc atttcctttc attgggatat
     7801 atacgttctg atcagtcgaa gacaagattt cctgacttac tccctgacct tcgtttccca
     7861 tgattatagc gaaatcctct gttttttcta ctttgtctaa tgcatgtgct tcttcattta
     7921 attctgtacc gtacaccgta aaccctttgc ctttcattac agggatcact tctgccaaat
     7981 ctttttgtaa cacaggcaaa tgataattgc ttccctgcat gcttcgcagc acctttgtac
     8041 tataaatatc tgccgttcct ttacctaata aaacaccagc cataccaaac gcatctgccg
     8101 tacggatcat cgttcccaca tttccaggat cctgtacatt atctagtaaa agccagcctc
     8161 ctgaaaaatc tggcgtatct tcagatgtta acgtcatcac tgctaagatc ccttgcggtg
     8221 taggtagatc tgacatagcg gtcatgacct catctgaaac tagaaaagta gaaatctctt
     8281 tgtttacagc cagccagtct ccccattctt tcatacctct ctgtgtcaca aaaagttctt
     8341 ttatttctgc atcagacgac gcagcttctt cgatcagatg gaacccttcc aaaagatatt
     8401 ctgccttttc ttctctgtat ttctttttat gtagtttttt taattctttg attcttggat
     8461 tttttactga ttggatctct ttcacattcc tcacctcaac tgattatatc atggaatagg
     8521 tgcttgagct tgtttcatcc taaaaaaatc ggtatcattg atttataaaa caggaaagaa
     8581 aggtgacgaa catgcgcaaa gttaaaatga atgtccaagg acgtgtccag ggcgtgggat
     8641 ttcgctatat gaccaagatg gttgctgatc agttaggcgt gaccggaacg gtaaaaaacg
     8701 aagacgacgg ctcagtcaca atcgaagcaa tcggaaatga cgacatcatc caaaaattta
     8761 tcgaagaagt caagaagtct ccgagcccaa gtggacgagt gcagtatgtg gatgtccaag
     8821 aagatccgat gattgaggaa cgaaagaaat ttgatgtggt gggataaggt tgtttttgaa
     8881 gcgctttgcc tcgagtatta aggagaaaca ttttccaaat agcttctcat attttgaaat
     8941 gtaatgactt aataccgaga ggcagctgat aaaacaccgt caataaggtt gtgaaaaagc
     9001 tggtctgcat caagcattaa ggactggttg tgaaaaatag ctctccatat ttttcaacag
     9061 gctggactta atgccgtaga tgcaagcttt tgaacatcgt cgataaggtt gcgaaaaagc
     9121 tgatctgcat caagcattaa ggactggttg tgaaaaagtc gcttagtttt gagtattaag
     9181 gaaaattttg tgaaaatggc tttccacatt tttgcataaa tttgacttaa taccaagaaa
     9241 ctgacttttg aacatcgtcg ataaggttgt ttttgaggca ctttgcctca agtattaaag
     9301 acaggtagta aaaaagctga tctataactt gcaataaatt tgcttaaccc atattttcca
     9361 gacagaacaa aaaagttttt agttttttaa ataagaaaga aacacttgga atcactcttt
     9421 tctttctaag tatttctttc ttgatttttt gtcttttttc aaaatttttc gctacgaaaa
     9481 agaacgaata tttatatgaa atttctatga agttgattga attccatgcg cttttttagt
     9541 atagttaagt ttgtgtaaaa attatagaag aggaagtatt ctatgaataa atggaaaaac
     9601 tggttattgg gatccggact tgtcagtatc ctgctctttt tatctggctg tgtgcggatg
     9661 gattcaaacg gaaaccctga cacttcagga atcgtttatc gagtactcgt ccatcctatg
     9721 ggccaagcga ttacatatct agttgagaat ttcaattggt cttacggctg ggcagttatt
     9781 gcaatgactg tgatcgttcg tatcatcatc ttgccactag gtatcagtca atcgaaaaaa
     9841 acaatgatcc aatctgaaaa aatgcaagcg ttaaaaccac aagttgaagc agcacaacaa
     9901 aagctaaaag ctgcaacaac acgtgaagaa caaatggcag cacaagcaga aatgcagcaa
     9961 gtatatcgcg aaaatggatt gagtatgacc ggcggaatcg gctgtctgcc tctattgatc
    10021 caaatgccga tcttctctgc cttgtatttt acggctcgct acacagaagg tatccgtgaa
    10081 tcatcttttt acggcatcga tctaggctca ccaagtatgg tgcttgtggc catcgcaggg
    10141 ggcgcttatc tgcttcaagg atatatttca acaatcggta ttcctgaaga acagaaaaag
    10201 acgatgcgta cgatgctgat cgtctctcct gctatgatcg tcttcatgtc gatcagtgcg
    10261 ccagccggtg ttacacttta ctgggtagtc ggtggtgtgt tcagctgtct gcaaacattc
    10321 atcacaaacg ttataatgaa accgcgtttg aaagcacaag tggcagaaga gttgaaacaa
    10381 aacccgccaa aacaagtcgt tactccaaga aaagacgtga cagaatcagc agcaaagcca
    10441 gctgacaaca aacaagcaac aaaacaaatc aaacaaccaa aaaacagtac aaacaacaaa
    10501 ggccgcaacg caggaaggca gcagaagcgg aaataaaaat atatgacaaa aaactgtaga
    10561 caaataaaaa aatttctttg ttctacagtt tttttgttac aattaaagaa aacgttcgca
    10621 tttcgaggag gaatgtataa tgatgtccaa ataatcaatg tatagtcgaa tggaagaaga
    10681 caaaatttcg ctagatgcac ttgttcctaa aaatcattta gtccgtaaaa ttgacaaatt
    10741 attgtcattt gattttattt atctcattgt tgaatcaact tactcgacca ttggtcgccc
    10801 tagcgttgat cctgtcgtct tagtaaaatt agtattcatt caatatttat ttggaatttg
    10861 ttcgatgcgt cagaccatta aataagttga aacaaaccta gcttatcgtt ggtttcttgg
    10921 gcttagttta attgataaag ttcctcattt ttcaactttt ggtaaaaact atgcacggcg
    10981 tttcagagaa accgatttgt ttgaacagat atttatcatt attctcgaat aagcagttga
    11041 tgctagattt attcatgaag aaattttgta tatggattca actcatatta aagcgaatgc
    11101 gaacaaacgt atttttacaa gagatatggc acataaagaa gccattttat accaaaaaca
    11161 attagaagaa gaaatcaatg aggcaagaat tgccgaaggc aaacgtcctt ttggttcaat
    11221 cattcgtcag gaggtggtcg aaagaaaatt tagcatcgca gatccagaaa gtggttatta
    11281 tgtaaaaaca gaacgagaaa aacagtttgc ttattctgct cataccgttg gtgatgaaaa
    11341 tggttttgta ttagatgtca tgattacgcc tggaaatcta catgatagcc gaatgctcgt
    11401 gccacaaatc gaacgcgtta aatcacgtta tggtgtagct gctaatgctg cgtacaaaac
    11461 accttggaac gtcaagtatt taatcgaacg aaaactacga cccattctcc cttatatcag
    11521 tttcgcacaa ctactcgaga tggctataaa aaatatgtat ctaaatcttt tatttgtgaa
    11581 agttgtccat tattgaaaaa ttgtacagaa agccaaaaac accaaaaaga aatacatcga
    11641 catatttggg aagactactt agatgaagca gaacatttac gccatacggt gtacaatcgt
    11701 gaaaaatata aaaaaagaaa agaaacgatt gaacgcattt ttgcagacgc aaaggaaaaa
    11761 catggaatgc gctacaccaa gtatcgaggc ttggaaaaaa tcaggtgcat acaatgcttg
    11821 tttttgtcgc aatgaatctg aaaaaattag ctacttggca gtgggagcat atgtcgttat
    11881 atcttttatt atacaaaaat agacaaaagt atcagtctac actcttagta aagaggaaac
    11941 tgatgctttt gtctacagtc ttagagagtg ggacaatagt tttttcttct ttacgtcttt
    12001 tcctctccat gtattttcct aattttctta atttaacgcc atgagtgcca agccaatgtc
    12061 aatcttggct ccttgtttcc ttcataagtg gaaatccgtt tccgatagat cgaaccttct
    12121 ttttcctcta aaagtttttt tacattctgc tttgaaataa cgccatgtat tattcactaa
    12181 aatttgtcgg tttcgctcac tttttgcttt cgtacattga ctacgaacag gtcagcaccg
    12241 accactttca cattcgtaaa ttttgaagac acgtataaat ccacttttat cttttcttcg
    12301 actaaagcgt tgaccgcaaa agcgacatct gtttcagaaa tatattgttc catatctaat
    12361 ggtaaaattt tttggttgat ggtataattt ttaaacataa agcactcgct tcctttctga
    12421 ttgggtttgg tcactttaat cctacaggga tgagtgcttt ttgtgtacct taaaatcagt
    12481 aaatatccat ccgtgaaaac gggtggcttt ttaacagccc tagaagggct caccactcac
    12541 agccctatct ctctttaact atttaaatgg atctacatac tcttgtttac ttatactgtc
    12601 tctaattcga tcatctgctt cttgttctca aatatatatt tcaattgttt tttgatttaa
    12661 cccaaccgta ctcacgtagt atcctttggt ccaaaagctt ttattcccat acttatattt
    12721 caaatttgca tgtttttcat ggattaaggt tgcacttcgt ccttttaagt agcccataaa
    12781 actagaaata ctaatctttg gcggtattct tactaacata tgaatgtgat caggcattgc
    12841 atgagcttca atgatttcaa catctttcct ctcacacaat tttcttaata tctggccaat
    12901 acttactctt aactttccat aaatcacttt tcgtcgatac ttcggggtaa agactatgtg
    12961 atacttacaa tcccatctcg tatgtgctaa acttttatcg ctaaagctat ttcgtccacg
    13021 cgtagaaacg cgcgtttttt tgtttcgtac gctacgccaa cgaaactgac taaagtcaat
    13081 aaaaaaagtg gggcaataat cagatttttt tctgactatt gtcccactct ctttttatta
    13141 ctcttcatct tctactattc cactaattaa ttagttgaca gatacaatgc tttcacatcc
    13201 tgcacgaaca aactcgggct ctgaaccaat cacttgcgag ttgataaatt caatgaccat
    13261 aggaagatta atccgacata aagtttaatc tgttgtcctt ccattatcag tttagaaatg
    13321 atattagtag gtgtaccgcc taaaagatcg catagtacca caaaatcatt taacgaatct
    13381 atgacagtaa gagcttttgt ctgtatgttt cagtgccatc ttctggtaat aaaggtaacg
    13441 tgtagatatt ctcttgaggt cccataatca tttttgtact ttttttcaat tcctcacaaa
    13501 attttccgtg actaatcaat atcaattttc tactcatttt tggctctccc ttatttcgaa
    13561 atcacacaca atgcagataa agccacacac aagtaatacg ataaaaatcg ctcgagttgg
    13621 gtcatatttt tctttcctaa caaccaataa acacctcgac gatcccagcg agtaagattt
    13681 tagataatat catatcgata tagttttgca tattcaatgt cacatcgcca atcgttggta
    13741 ccataaaaat ttaatatcaa tcattgttgc aactaatgct cctaccatga acactcttaa
    13801 taaagtcgct acgtccgtta atacagttaa gcgagattac actagatgat ctgttcctgc
    13861 caaggcaaga gccagaagcg gttgcctgcc catttgcctt tggtgtgtcg gagctgtccg
    13921 ataaagttca ccgcccgatc cgctctggct ttgtcgtagt gacattccga aagcatgaat
    13981 cggcttggtg tgtattcctt taatttggga tagccctttg gtctggtttc tgccatcagc
    14041 taccacctcc caacagagcc tccatcgcat cttctgctcc gacaccaccg ccatcaccgg
    14101 caatgatacg gcttctggac gaaggcgtca gaccgaactg ctcggaaaat cggttcataa
    14161 ttttcagata ggtctgggca ataaacacct gtggtacctg ctgccaatag ccggataggg
    14221 ttttcacgat gataccgtgc tgggtaatga attcctcggc ttccttccag cgggcgtagg
    14281 cttggcacta accggcaaag gcagccatat ccacatctgt caagattccg atggcctcca
    14341 tctgctttgc cagacgcttc cattccttct ttgcctctgg ttccagccac ttcggacagg
    14401 tcggtgcctt cttttccggc gttgactctt ttgcattgag tgggcgattg cccggatttc
    14461 cctccagctt cttcatggct gtcggggttg attttcttcc tctggttgcc acagtcgtca
    14521 cctcccttca atgtatttct gccagtagac agagaacaga gccaagtcga aacctgactc
    14581 tcttctctat ctgctaactt gtatttcagt ccactcttct gatgaatcgc acccgcagga
    14641 ttttcaagat gccgcaggca aattccaaga agtttctgac cgcatcataa ccatcgtagc
    14701 cgtgtagcca catccttcca cctcgccgcc gtcctcgtcg ctgatataaa tgattctgta
    14761 ttcgctcatc tgttgttttc tccagtcttt tgtttttttg tagtacatat atcactctaa
    14821 aagtgattat tatcaagtcg tttgaaagcc ataatgtaca caatcattcg actggttttt
    14881 ggttcataat tgaccgccaa agtgagcaaa agaaagggac ctctgtctgt ttcagaagtc
    14941 cctttcggta tttggttctt agtggttcag gctgtattct caaacctcat actcatcttc
    15001 gaggtctgcc tctgcaatga tctggccgat gctgtcgtaa cgctggacct gcatctggat
    15061 ggcatccttg tctgctccct cgtccatcat cttcagcagc ttgtctgatt cctttttgta
    15121 ggcccagaaa aggatctcct gaaggctggt ctcctgcttt ttcttgcgaa gggcgacctt
    15181 cttctcttcc accgcctcgt tcaacttggt gaactctgcc caagcaagga taccgtctcg
    15241 cttgattgcg atctccacat ccttcagctc cgggatggtc tttgcaccct tgatctcctt
    15301 caaatatttc tttgcctttt cgctcattgc cattagcgtt tcctccttgt ttttgggatt
    15361 ttcccctttg gttgtgtgta tattgccata gtctctcgac tatatcaagt caatccacag
    15421 gcatatacta cacaatcatt tggagctgta tttgtataca ttatgccgat ttat
//
LOCUS       DADVXM010000060        14937 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.063, whole genome shotgun sequence.
ACCESSION   DADVXM010000060 DADVXM010000000
VERSION     DADVXM010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.063"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            168..1907
                     /gene="yfcC"
                     /locus_tag="KB927_001963"
     CDS             168..1907
                     /gene="yfcC"
                     /locus_tag="KB927_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBB6840873.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2064..3248
                     /gene="iadA"
                     /locus_tag="KB927_001964"
     CDS             2064..3248
                     /gene="iadA"
                     /locus_tag="KB927_001964"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBB6840874.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3359..3562
                     /locus_tag="KB927_001965"
     CDS             3359..3562
                     /locus_tag="KB927_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBB6840875.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3663..4325)
                     /locus_tag="KB927_001966"
     CDS             complement(3663..4325)
                     /locus_tag="KB927_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840876.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4338..5840)
                     /locus_tag="KB927_001967"
     CDS             complement(4338..5840)
                     /locus_tag="KB927_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6840877.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6388..8067
                     /locus_tag="KB927_001968"
     CDS             6388..8067
                     /locus_tag="KB927_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBB6840878.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8194..8673
                     /locus_tag="KB927_001969"
     CDS             8194..8673
                     /locus_tag="KB927_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBB6840879.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8892..9572
                     /locus_tag="KB927_001970"
     CDS             8892..9572
                     /locus_tag="KB927_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBB6840880.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9580..10911
                     /locus_tag="KB927_001971"
     CDS             9580..10911
                     /locus_tag="KB927_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6840881.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10926..11888
                     /locus_tag="KB927_001972"
     CDS             10926..11888
                     /locus_tag="KB927_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBB6840882.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            11999..12337
                     /locus_tag="KB927_001973"
     CDS             11999..12337
                     /locus_tag="KB927_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBB6840883.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12416..13123
                     /locus_tag="KB927_001974"
     CDS             12416..13123
                     /locus_tag="KB927_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBB6840884.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(13226..14707)
                     /locus_tag="KB927_001975"
     CDS             complement(13226..14707)
                     /locus_tag="KB927_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6840885.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         4750 a         2557 c         3193 g         4437 t
ORIGIN      
        1 atggaaagag aaaaaaataa tcatacatag gagaaaaaaa acaaaataga aaaaagtgat
       61 tttctaataa attattcatg tggaaatgtc atttttactg tataattcat ttgattatcc
      121 attttttatt catcaaaatt actgaaaaaa gaaaggaaga aataaatttg aagaaaacaa
      181 attcttcagg aaaaccgaaa cgcgacttca ctaaattatc gacaccccat acgtatgtca
      241 ttatttttgg tgtagtcatc tttgcatgga tactgacttt tgtcgttcca gcaggaaagt
      301 tcagcacgca agatattgaa tacaaagatg caaatggcga aacaagtact cgtactgttt
      361 tacgtcaaga ttccttccgt tatgcttacg agctggataa gtcgtatgtg tttgatcaat
      421 tagaagaact gcaagatcat ccagcagaac gtgaaaaact ggatgttccg gaaaaaggat
      481 tggaaaaagt cattgctgac ggagaaaaaa atcttacgca ggaaaaacta gatgaaatct
      541 ccttgacaga tgatgtgctt tacgatcagt acggcgaaaa tatctatgat acttctaaaa
      601 aattgcataa aacagccaaa atatggggaa cagatgattt tggcggcttt ggtttcttaa
      661 attttgtttt tgaaggacta gtatctggag ataagtatgg atctgctgta gggatcgctg
      721 cattgatcct tgttgttgga ggtgcttttg gtattattat gcgtaccgga gcgatcgacg
      781 caggtatcta tgcgtttatc agtaaaacta agggactgga gcgtttagct ttaccgctat
      841 tattctttgc tttttcattc ggtggcgcta cattcgggat ggcagaagag gtaattccat
      901 tctcaatggt gatggttcca tttgtcattg cgttaggata tgactcgatc gtagcagtaa
      961 ccgtgactta tgtcgcatct caagtcggaa atgcgacctc ttggatgagc ccgtttagcg
     1021 tagcggtggc tcaagggatt gctggaatcc ccgtgttgtc tggtgcgaca ttccgattga
     1081 ttatgtgggt agttgttact gcattagccg ctggttatat gatgatatat gcagaaaaaa
     1141 tccgtaaaaa accagaaagt tcgttgactt acaaatcaga tgattatttc cgttctcata
     1201 tcaaaaagac atctgatgaa aataaaaaat tcatgcttgg gcataaattg atcttattag
     1261 agatgttagt tgtccttgtc tggatcgttt ggggcgtgac tcaaaaaggc tattacattc
     1321 cagaaatcgc ttctcaattc tttgtgatgg gattagttgc tggaatcatt gctgttcttt
     1381 tcaaattaga tggaatgaaa gtcaatgaca tcgcttcttc tttccaatct ggtgcagctg
     1441 atttagctgg tacagcaatc gtagtaggta tggccaaagg gattcttctt gtcttgggag
     1501 gatctgatgc atctgttcct tcagctttga atacgatttt gcatgggatc gggacggcgt
     1561 tgaccggtgt tccagctgtc attggtgctt gggcgatgta catcttccaa agtttgttca
     1621 acttggttgt tacatcaaat tcaggacaag cagctttgac tatgccaatc atggctccac
     1681 tggcagattt agtaggtgta tccagacaag tagcagttct tgcttatcag cttggttcag
     1741 gttttatgga cgcttttaca cccgtatcag ccagcttgat tggtgtgcta ggtgttgcac
     1801 ggatcgaatg ggcaaaatgg gcaagattcc aaatcaagat gcaaggattc ctgtttgttt
     1861 taggaactat tttcatcatg attgccattg caataggtct gcagtagtac tggagacctg
     1921 taaataaaaa agtaatccaa acagtagata aggactccaa gaaccgtcat tttacggtaa
     1981 aatcaaagga gtaaagatcc tatcgtttgg attatttttt aagatcctat catcagttat
     2041 acttaaagaa agaggaaaaa tgtatgaaaa tcattcgaca aattgaagtg tttgcaccag
     2101 attacttagg aaaaatggat gtactgattg ccggtgggaa gattttggct gtagaagaac
     2161 agctagaagg cggctacgaa ggagtggaag tagaagaact ttcaggtgag ggaaaagtac
     2221 taaccccggg tttcattgac tgtcatttcc atattttagg tggaggagga gaaggcggtt
     2281 atcaaaatcg aacgccagaa gtcacattga gccaattgac tacagctggt gtaacgacag
     2341 ttgtcggttg tttgggaaca gacggagaag gtagagatat gactgcgttg atcagcaaag
     2401 cgaaaggtct ggaagcagaa ggaatctcca cttatgtata cgaaggttcg taccgattgc
     2461 cggtaaaaac agtaacagat tctatcatca aagacttttt gacaattgat aaaattatcg
     2521 gaatcggaga aatcgcagta tccgatcacc gttcttctca gccaagtttt gaagagttcg
     2581 ctcgtgcagt agcagatgct cgtgtaggag gcatgttatc cggaaaagct gggatcatca
     2641 atgtccactt aggcggagga aaaagaaagc tagagctatt gacacgaatc gtagaagaaa
     2701 cagaaattcc gatcacacaa tttttgccta ctcatgcaaa tcgcacacca gaattatttg
     2761 aagcttgcgt ggcatttgcc aaacgtggtg gcacgattga cttcactgct agcgaagatc
     2821 ctgatttttg ggagaagaca gatggtgaag ttcgcttcag caaagcactg aaacgattga
     2881 tcgaggaaga tgtttcttta gataatttca cgatgacctc agatggacaa ggaagcttgc
     2941 cttattttga tgaaaacaat catttcctag ggttaggagt aggaagtgcc aaggcattgc
     3001 tagtagggat caaagaagct gtgcaaaaag aaagtatccc tttggaaatc gccttacgag
     3061 ctataaccag taatccagca cgtatattga aattggataa aaaaggaaaa atcgaaattg
     3121 gtgctgatgc agatctgtgt atcttggata aagaaacgct tgatattgat acagttatcg
     3181 ctaaaggaga aataatggtc caagaaaaag aagtcaaagt atgggggact ttcgaaaaaa
     3241 gtttttaatc aacagctcta actatctttt ttagaaaacg agcgttctgt ttgtctgtat
     3301 ctgttgttga tgttaccctg aaggtagatc aataaacaaa ctaagaggag gaagcacaat
     3361 ggcagattta aaaggacgtt ctaaagatat gaaagataaa gtagtcggtg aaggaaaaga
     3421 agcatacggc aaagcaacag acgacaagag caaagaaaca gaagggaaag cacaatcact
     3481 aggtgctgac atcaaagaaa aagctcgaaa tttaggcgac gaagtcaaag acaagttttc
     3541 tcgaaaagac gaaaaaaaat aaaaaccact tattactaat tgaatcaagc aaataaaaaa
     3601 tccgaaccat atctgcgaga cagatatggt tcggattttt tatttgatca ttatcctgtt
     3661 ttttaaactt cgattttttg aaatttttta ttttttagtt caaagacttc atcacagctt
     3721 tttgctactt caatctcatg agtcacgatg ataatacagc gattttgttc atgggcgatt
     3781 tcttggaaaa gtttgacgat atcttgtgaa gttgtttcat ctagatttcc agtaggctca
     3841 tccgctacga ttagttgatg ttcacagcag atagcacgaa cgatagcgac tcgctgctgc
     3901 tgacctcccg aaagtttggt cacctgtttt tttgctaata tttcatcaat tcctacacga
     3961 gccagtcgat ctaaagcaac ttgtcgataa ttctcttgct tggtcttagt gatttccatt
     4021 gctgctatga cgttgtctag agccgataaa taaggaagca agttgtaagc ttggaaaata
     4081 atcgagacat catttttacg ataacttctt aacccgattt tgttcagtga acgatcttga
     4141 tagtatacct ttccttcttt tggtgcatct agtccagaaa taagcgaaag aaaagtcgtt
     4201 tttccagaac cacttgctcc taaaatagcg tacatttttc cagcttcgaa attcagttct
     4261 acatctttat aaagcgcatc ttgcggatct tgataccaaa atcccaattg ttctgtccgt
     4321 aacatcaaat tcctccttta gtttaatagg atttttcttg ggtttaatct taatatccct
     4381 atagaagcta aaaagacaga aaacagactg attccaaatg ctactccggc taatagtccc
     4441 aattgtgcag gtttgacatt gatttccaat tcgctgactt gatcagaaac agcaaatgga
     4501 ttattcgtgg ttccttgttg accatcgcgt tgaccgcctt gttcttgtct gttacctggc
     4561 atttgtccac cgccaggagc ttgctggttt tgtgtcgtgg tttctgtctg ttggtcaagt
     4621 agctgctgtc ccacggcatt cgcgacgacg tttccgctaa gcgaagcaac tcctaatgca
     4681 agaatcatac aaatagccac ttcggtaaac aattggagaa tgattttact tctggattct
     4741 cctaaagata gcaagacgcc taactcatgc cgacgctccc gaatggtaat cataatgatc
     4801 agagtaagta tgataatacc ggctacagcc actagtaaaa caacattttt agaaaaactt
     4861 gccacgttgt ttaaaggttc caacattgac tgatacatgg aatcatttga ttgtaagcta
     4921 aatgtatctg tgtcgatcag cttctcagct tctttgagaa actcatccat tttatctgga
     4981 tcagatagag tgtaaatagc agaatctatc gtgttatcgt cagatgtccc atttagttca
     5041 tttgcaaaag tgtaagaagt gtaaagtgta ttcgacggat tcatgaagtt gaatttcata
     5101 cccatactgc cgcttgtttc gctggattca taaattcctt tgatcgtcat ttcataagtg
     5161 gtatcttcat cttcagtact cgtgattgtg aaagtatctc cgactgccag gtcatttgtt
     5221 tctgctagag tagaatcaat gactacattg tttgtgcctt tgtcgctgtc atctattcct
     5281 tcaccatccg tgatttttgc tgttccatca gaaaaattac tattttgtgc agttgctgac
     5341 acaccactga tttgaaagtc tgcttgagtc atttgcggat tcccgcccat tcctccagca
     5401 ggttcaccgc ctgcatcagt agtttctgaa ctgtcttcac ttgaatcaga actagtgatg
     5461 gcagttattc catcttttgc catagctgag gcggaacttt caaaggaata actctttaca
     5521 ttatctaatt cagctatttt ttccgcgtcc gttaaggaaa ctggtgtaag agaaaaactg
     5581 cctggatctg gacgttcttc agtggtagaa ccgcttgaag aagtttgttc ctgtttttta
     5641 aatgaagctt ctcgattggc acttaaagtc actgttgctc caacttcttt ttgtgcttga
     5701 ttcgctgctt cttctgcagc gcttcgaatc gtgaggccag ctagcacaaa aataagaatg
     5761 gctgtgaaca cggcaaacaa taacaatgaa cgtccccatt ttacttttgt acttttccat
     5821 gcacgtttca taaaattcat attttgcatc cctcctagta gatgcatttg ataatagaca
     5881 acctatctta aagctagctt aaatcttatg ctgtttgcac accatcaaca tgaggttctg
     5941 tatatataaa aagtcactat agttattgca aaaaatgtgg taaaatgaaa aaagtatgtt
     6001 tcaaaccgac gaagaagaaa tgaaagagga atagcaaaag aaatcctaga tgctacagag
     6061 ggatttttac gtgcatagtt gttctaacaa ttgctgatac tagcgattta gtttatttgt
     6121 tgtataataa tggggaacag ctgaatactt atataagtat tctggctata gcgtttcgca
     6181 aaagatccat tttgttaatg aagtatatcc aaaataaaat gcccatccaa ctgtcagaac
     6241 gcggatgtgc tggtaatttt cctgctgatt ctccataagt tgagaaatag tgattttgca
     6301 tatgcttcat tggaatggct catatattta gataaagaag aaaatcgaca tctttaaact
     6361 tggatgtcat aagaagaggt gaagtttgtg agtaccatta aaattatccc attaggcggc
     6421 gttcgtgaaa atggaaaaaa catgtatgtc gcagaagtgg gcgaggatat ttttatttta
     6481 gattgtgggc taaaatatcc tgaaaatgag ttgttgggga tcgacgtcgt aatccctgat
     6541 tttacgtatt tagaagaaaa cattgatcgt gtagctggtg tctttttaac acatggacat
     6601 gcagatgcga tcggggcact tccttacttg ttgtcaaaaa tttctgtacc agtattcggg
     6661 acagagttga cgatcgagtt agcaaaattg aatgtcagtc gtaatgaagc agccaaagga
     6721 tttaaggatt tccatgtggt agatgagcat acagaaatag actttggtga aacagtagtg
     6781 agctttttcc gtaccactca tacgatacca gattcagtgg ggatcaatct gaaaacaaaa
     6841 gaaggtagta tcgtttatac gggagatttt aaatttgacc aaacggctat cccaatgtat
     6901 caaacagatt atgcacgatt ggcggaaatc ggcaaagaag gagtcttagc cttactaagt
     6961 gaatcggcaa atgcagaaaa tcctcagcct gtagcttctg aagcccaaat agcagatgaa
     7021 gtatttgata cgatcaaata ttgggaaggg cgtatcatcg tcgcttgtgt agcaagtaat
     7081 ttgcaacgag tgcaacaagt attggatgca gcagaaaaag cacaacgaaa agttgtcttg
     7141 actggtcaag atttcgaacg aattattcgc acagcgatgc gtttagaaaa acttcaatta
     7201 ccaagtgaag atctgcttgt tacgttgaaa gacatgaaaa actatgatcc agaagaactg
     7261 atcattttag aaactggccg aatgggtgaa cccatcaagt ctctgcaaaa aatggcaaac
     7321 ggtacacacc gtaatgtcaa gattgaagaa ggagatttgg tttatatcac tactacgcca
     7381 agcatcgcga tggaaaccat cgtggcgaaa acggaagata tcatttatcg agctggtgga
     7441 acagtgaagt tgatctctga gaatatgcgc gtttctggcc atgccaatcc taatgacttg
     7501 caattaatga tcaatttgat gaaaccaaca tattttgtgc cagttcaagg agagtatcgt
     7561 gaattagctg ctcatgcaga tttggctcat gcagtaggga tgccatacaa aaatatctat
     7621 attactggac gcggagacgt gctggaatat aagaacaagc gtatgagtgt tgcaggaact
     7681 acaagtgcag aaaatgtaat gattgatgga ttaggcatag gtgatatcgg aaacattgtt
     7741 ttacgtgatc gaaaaatctt gtcagaagac gggattttcg tagcggttgt cactatcagt
     7801 cggcgagaaa agaaaatcat ttcaaaacct caaattactt cacggggatt cgtttacgta
     7861 aaagctagcc gtgatctgat gaaagaaagc agcaatatga ttgaaacaat cgttgagaaa
     7921 catttagaaa gcaatgattt tgagtggagc aaattaaagc aagacatccg agatcaatta
     7981 ggccgttact tatttgaaca aacaaaacgc cgcccagtga tcttgccagt cattatggaa
     8041 gctactcaac gtcgaaataa aaaataaaca aaaagagtaa gatgaacctc tctatagagt
     8101 gctcgtcttg ctcttttttt gcgaaaaaca aataattttt gaatacagca tccctcgctt
     8161 tataataaac gatagaataa agggagtgaa tcaatgatga gtcaaacaaa agtcgaacgt
     8221 tatttagaag aacaaaagat cagctatcaa ccacttgatt ttagtcatgt ggtagaagaa
     8281 tctttcacag aagaactaca aaaaagaggg attgatccag ctttgatatg taaaactctc
     8341 gtagtgaaag gaaacaaaac tggggtgatc atcgcattga ttcctttgaa cgatcactta
     8401 gattacaaaa aaacgagaca agtgacgaaa gatcgtaaag ttggttttcc tggaatggat
     8461 tttgtattaa tgcatacagg atatccccac ggagcaaaca cccctattgg aataaaactc
     8521 gcacatcctg attattgttt tttagcagac agttctttaa aagaaaaaga agaagtaatt
     8581 gtgtcaagcg gtgaaatcgg gagaagcctt cggataaaag tagccgattt agaaaagatc
     8641 gtccatccta tttacgctga tttaattagt taagggacga gaagagaagc taagcagagc
     8701 agagacctca aacttgagat tatatctgct tggtacttgg tgcatcctgt attatctgtt
     8761 acaattgctt tgtacatact gtactatcaa tccaatgaaa atatatttag cagctatatt
     8821 ttttcattga tgtgcaagtg atgaaatcgt ttttaataaa aaagatacag agaaaacgcg
     8881 aggtgtaaaa tatgaaaatt acgtatcatg gacattcctg tttaacaatt gaaatggaaa
     8941 atggccaacg cgtgatgatt gacccgttta ttacaggaaa tccattgaca gacttaactg
     9001 cagaagaagt aaagacagat tggttgctga ttactcatgg tcatagtgac cacataggag
     9061 atatgattcc tattgcaaaa gaaaatcaag ccacaattat cagtattgtt gagattgctg
     9121 attatgcgaa cagcagagga gtagattcat tcggtatgaa tatcggtgga aaacatgcgt
     9181 ttccattcgg cgtggtaaaa ttcgtacatg cacagcatag ttcaagctat gaagtagacg
     9241 gtatcgttca gtatatgggc gagcctagcg gaattattat tcaagcagaa ggaaaaacga
     9301 tttatcatgc aggggatact gcttatttca gtgatctagg attgcttgca gaagaattcg
     9361 atattgatgt cgctttcttg ccgattggcg ataactatac gatggggcca gaagatgcag
     9421 caaaggctgc gcaaacaatt cgtgccaaga aagtagttcc aatccattac aatactttcc
     9481 ctgtcattga acaagatccc gaatcttttg tagagttact ggaagatagt gaaggaaaaa
     9541 taatgagcgt ctcggaaacg ctggaagtgt aggcagaaaa tggcgacaaa acatgatttg
     9601 attttagaat atattgaaag tttacctgtt ggcaatcgaa tttctgtaag aagcatcgca
     9661 aaagaattga atgtcagtga aggaacagcg taccgtgcaa tcaaagatgc agaaaatgtc
     9721 ggactagttt caacaattca acgagtaggg accatccgta tcgaacgcaa attaaaaaaa
     9781 catattgaac gtttgacatt tggcgaggtc gtcaggatca ttgaagggga cgttttaggc
     9841 ggggcggcag gattagacaa ggtcttgaat aaattcgtca tcggcgcgat gactaaacat
     9901 gccatggaac gctatattac gccaggatca ctaatgatcg tcggcaaccg ggcggaagtc
     9961 caaaaattag cattggaaga tggcgccgca gtattgatca caggaggatt caatacgact
    10021 gctgagattg caaagctagc tgatgatctt gaaatgccga tcttacgcac ctcttatgat
    10081 acatttacag tcgcaaccat gatcaaccga gcgttaagcg accaattgat caaaaaagat
    10141 atcatgcttg tcagtgatat ctatatgcca gctgaaaaga ctcattattt gcagcagaca
    10201 gatacgattt ctgattatca gcgtttgtca gaagaaacgc agcattcgcg ttttccagtc
    10261 gtcaaccgcc atcatcgttt gatggggatt gttacggcaa aagatgtttt agggaaatcg
    10321 ccaaaccaga tcatcgatcg ggtgatgacg aaagaaccaa tcagtgtaaa gaaaacaatg
    10381 agtattgcct ctgttagcca tcaaatgatc tgggatgggc tagaagtcat gccggtcgtt
    10441 tccgatgact tgacattgga aggcttgatt acccggcaag atgtaatgaa agcgatgcag
    10501 cttgtccagc gacaaccgca gattgcagat acgatttcgg atcagatatc tggaaatatc
    10561 catacgattg atactgaccg tgaaggaaat cgtttggaaa accctaagtt caaattcgta
    10621 gtagcaccac aaatggtcaa tggcgttgga accatttctt ttggcgtact tagcgaaatc
    10681 atttctgatg tcgcacaaaa aacaatggtg atgaaccaaa aacgaaatat cttgattgaa
    10741 caagtgaacc tacattattt gcggctgatc caattggaaa gcgaattaga cattcgtcca
    10801 cgtgtattgg aaatcggcag acgttccgct aaactggata tcgaagtgtt tattgaaaac
    10861 accatcgttt ccaaagcaat cgttgtttgt caagtaatgg aacgttctta gaaagcagga
    10921 gtgaaatgac agtacagcaa gaaatagtag atacaataaa aaaatacgat aaaatcatta
    10981 tccacaggca tttgcgccct gatcctgatg cattaggatc acaagtagga ttagccgaac
    11041 tattacggga aagtttccca gaaaaagaaa tacgtcaagt aggtgaaacg attgaagggc
    11101 ttcgcttttt agcagaaatg caagaagttg aagatgtctt ctaccaagga gcgctagtca
    11161 tcgtgactga tacagctaat tcacccagaa tcagtgatca aagatatcag ttggcagaaa
    11221 aactgatcaa aatcgaccat catcccaatg atgaccctta tggagatctt gtgtgggtaa
    11281 atacaaaagc aagtagctgt agtgagatga ttgcagaatt tgctttgatg tttcctgaat
    11341 ctttaaagat gaacgttaag gctgcacggt tactttatgc aggaatcgtc ggagatacag
    11401 ggcgcttttt gtatccctcc acgacgtccc gtacattaga gattgcttcg atattgagaa
    11461 attatccatt tgatgcaagt gctttgaaca gagagattga acaaatgccg atgaaagtcg
    11521 ctaaactttc cggttatctt tatcaaaata tccaggtgga tgaaaatggt gcaggaagaa
    11581 taatccttcc gcaagaaatt cttgataaat atggaatcga tgattcagag acagcttcga
    11641 tcgtttcact tcctggagtg attgacgaag tgctggcttg ggggattttt gttcagcagc
    11701 cttcagggta ttaccgcgta cgtttacgtt ctaaggggcc gatcatcaat gaattggcta
    11761 aacgccatca tggaggaggc catccattag caagtggtgc gaatgcaaaa gatttagcag
    11821 aagtagagga aatctataaa gagatccaag atatatgcca atcgtataag agcagaaaaa
    11881 cagaatgata cttcgttcga aaacgtgcct tttgtagtaa aaatcacaaa tgtatctttt
    11941 caagatcttc tttttccgtt acaatagtgc tcactaaaga ttttaaagga gaaagaagat
    12001 gacattacca aattgcccag aatgtggctc agagtacaca tatgaagatc gaggcttgtt
    12061 gatttgccca gaatgcggga acgaatggaa caaagaagaa caagaaactg tcatagaaga
    12121 cggattagtg gtattagatg caaatggaaa ccgtctgtta gagggcgata gcgtgacagt
    12181 gattaaagac ttgaaagtaa aaggtgcgtc aggtgccatt aaacaaggaa caaaagtcaa
    12241 gaacatccgt ttagtagaag gcgatcataa tatcgattgc aaggtagaag gatttggacc
    12301 gatgaaactg aaatcggaat ttgtgaaaaa gaattaaaga atattcaagg tcttttcaca
    12361 ttcttttcct actactaatg ataaaataaa gtaaacgaaa aggagtgaaa cgaaaatgta
    12421 tggttatgga atgtatggtt ttttagatcc gacatttctt ttggtcattc ttggattagt
    12481 tatttccgga attgcgtcag cgtacgtcaa tagtactttc cgaaaatacg atcaagtgag
    12541 aagcaaaaac aatgtgactg gtacacaagc agcacaatat atattacaaa gtcaacagat
    12601 aaataatgtc ggtgttcaac aaattgccgg agatctcaca gataactaca attcaggtaa
    12661 taagatgttg agtttgtctc aagcaactgc acagtctact tcagttgctg cgataggtgt
    12721 agcagctcat gaatgcggac atgcggtaca agatgcttcg ggttatgtcc cattgaagat
    12781 tcgtgcagca cttgttccag cagctaactt tggttcgatg atttcgttcc ccttgattat
    12841 ggtaggtgta ttgcttagct ggaactctac gttaatcaat atcgggattt tcgctttttc
    12901 tttagcatta cttttccaat tggtgacatt accagtcgaa tttaacgcgt ctcggcgagc
    12961 aatccaaatt ttgagtgaag gcggactact gacggaagaa gaagtaccga tggcaagaca
    13021 cgtattattt gcagcagcac tgacttatgt tgcagcagcg ctttcgacat tcctgcagct
    13081 gttgcgcttg atcttattgt tcggcggcaa ccgaagagat taaaataaag aagttgtgaa
    13141 atcagcgctt tgatctgagc taataccgag agttagctga ttgaatacca tttatttgga
    13201 ataagaggat gtgacaagaa ttttgtcaca tcctctttgt tttgttctca taaccttttt
    13261 tcatatacag ttcatgaacc gcttttatta acttgccaaa taacactgta ttgtgcgttg
    13321 tatccagata gaaagtctcc gtttcatctg aaattttctc atgctgatct gtaatgatca
    13381 aatcagcatg ttctgaatat gcggtaattt taacagcatc tttgcgaaat aactgctgca
    13441 aatggctttg aagatgataa tttcctgtaa actgtttggt tatctgcaaa tggatgagta
    13501 actgctcttt cgtttctgtt tgtagtaagt gttggatcaa ttgactaagg tattgactga
    13561 tttggtttct ttccccattt tttgaaaaaa ttgtatcgat tttttctctt aatttctttt
    13621 cctgtataaa agaactagaa tgattggacg tggcttctgg aaagcaaagt gtagaaaaac
    13681 tactgctgga ttcacccaac agttcgaaaa aaacaactgc caacacaaga aaataaaaat
    13741 aaattggtat tttattttct aaatggttga gaggaaactg ttgagttaag taagtcatca
    13801 attgaccgac ttgtcgacaa ataaggtttt tgcttgtgga aaataaaaaa ccaatctcct
    13861 gtttttgtcg aaaagagatt tgatttggaa aaaaacaata gaaaaaataa ttaaagtagg
    13921 ctctctctgt ttctgtctct tcacaagggc gactcactga aaaagaagta aagtattctg
    13981 aataatcatg tgtatgctgc aataagtcca tcaattcagt gatttcagaa gaagtttttg
    14041 gaaaatatgc ctgttgtttg tttcgtaata tgaataaagt taacagcaag tagatatttt
    14101 tttcttgttt tgaaattttt tctatttgct catctgtact gttcattttt agtgcattta
    14161 attcaagtga ggaaaatggc caatcgttac ctccaaatgt atctgaaaga aaaaagtaaa
    14221 gatagagacg gatagataac tcatttcctt caagagtaca gcaatttttt acagatagga
    14281 tccgtaaatg gaattttttt aaggaatgat tgagctgttt tgtcagtttt tcgagatagg
    14341 agggcgatat ataaagttgt tcaagtaaat atttttttgg tacagcagtt tgtggataat
    14401 tgattagtaa catcaaatag ttaaaacgat tggattcttt taggtagcat aattttaact
    14461 tagaaaaaac agctaacttt ttagtttgat cggtttcttt ggtttggatc tctcctttat
    14521 gattagaata aataaattca tcaatcaata aaaattgctt gagtgataca tttatttttc
    14581 ggatcagttc tttgattgtc cgttttggaa tatgtaagtc attggataat tcttgtaaag
    14641 aacaattatt tttttgaatg accatttgta gaacaagtaa ctcttttttt cttgcttcaa
    14701 ttagcataaa tacctccttt ttattctgtt tttgtatata gttagacaaa aactgtgagt
    14761 ggaaagtcat ttcagtctgt gttattctca cagagtgtcg ccttcttttt tatataacgt
    14821 tatttaattt ttttgttacc ttgtttattc tattgtttat ttcctagggt attttgtcaa
    14881 gatattcttg tttttaaggc ggaaaaattg atttttaatg gatataacta aatatgt
//
LOCUS       DADVXM010000061        14748 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.064, whole genome shotgun sequence.
ACCESSION   DADVXM010000061 DADVXM010000000
VERSION     DADVXM010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.064"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(194..760)
                     /locus_tag="KB927_001976"
     CDS             complement(194..760)
                     /locus_tag="KB927_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6840886.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(760..1716)
                     /locus_tag="KB927_001977"
     CDS             complement(760..1716)
                     /locus_tag="KB927_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBB6840887.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(1716..2372)
                     /locus_tag="KB927_001978"
     CDS             complement(1716..2372)
                     /locus_tag="KB927_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBB6840888.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            2742..4760
                     /locus_tag="KB927_001979"
     CDS             2742..4760
                     /locus_tag="KB927_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6840889.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    4830..5036
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5187..7601
                     /locus_tag="KB927_001980"
     CDS             5187..7601
                     /locus_tag="KB927_001980"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBB6840890.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            7949..9502
                     /locus_tag="KB927_001981"
     CDS             7949..9502
                     /locus_tag="KB927_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBB6840891.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(9883..11667)
                     /locus_tag="KB927_001982"
     CDS             complement(9883..11667)
                     /locus_tag="KB927_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840892.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(11682..13403)
                     /locus_tag="KB927_001983"
     CDS             complement(11682..13403)
                     /locus_tag="KB927_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6840893.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13503..14264
                     /locus_tag="KB927_001984"
     CDS             13503..14264
                     /locus_tag="KB927_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6840894.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         4792 a         2724 c         2931 g         4301 t
ORIGIN      
        1 aaaagctgtc ctgcatcaag taataagaac agccaatcaa aaacagcttc tcatgttttt
       61 gatttggttg gacttattac cgcagatata agcttttgag caccgtgaat aaagaggtta
      121 tgaaatcaac gctctaacct gagtattaga gaaaaaaacg caaaacatat catttatgtt
      181 ttgcgttttt tatttatctt tttttctcaa tacaatataa aataggcggc tggttctttt
      241 ggttgataaa ccgataattc agcacattat atgtttcctg tggcagtttg gaacaaaaag
      301 aatcaaccat atccagttct ttttctccac cttcatgacc atagtagacg acaaggatca
      361 atcgtccgcg aggcacaagt cgtttcaata tttcttccat agctgtgcgt gtagtctctg
      421 gcatagtgat gattgcttta tcactttttg ggagataccc tagattgaaa atccctgctt
      481 tgagattttg ttgttcagct atcacttctc ctaacgtttc gtggccttgt agaaacaatg
      541 agacacgttc ttctaactga cgctgttcta gcctttcacg agtagcatcg attgcttgtt
      601 gctggatatc aaaactatag acatgaccag tttttccgat gtgttctgct agaaaaaccg
      661 tatcgtggcc attgcccatc gttgcatcta cgacgtgatc ccctggttgc aagatttctt
      721 gcagtaatgt atggctgaaa tgcaaagcag tttgcaacat cagacgctca cctttttccg
      781 tacatcatat tttccttgga agctatctct gcgaagaagt tcttcatcaa ttgcattcaa
      841 gacttcccat tttttcaagc tccacattgg tccaatcaag gaatcccacg gcgcatcccc
      901 tgtcaaacga tggatgatga tctcttttgg tatcatttcc agctggtcgc aaatgacatt
      961 gacatagtca ggacggctca ttaattgaag gcgaccttca tgatagtccc gcaacattct
     1021 cgttttgcgc atcagatgca tcaaatggag cttgattcct tggatatctg aatctaaaat
     1081 ggtgcgtctg acattttctt tcatcatttc taaactttcg cctggtaatc cgttgatcaa
     1141 atgcgtacaa acacggatat tatgtttgcg taatttagcc acgccatcta aataagtttg
     1201 ataatcatgt gctcggttga tcagttttga agtttcttca aaagttgttt gcaatccaag
     1261 ttctacccat aaatacatcc gctcgttcag ttcagcaagg taatcaacta cttcatctgg
     1321 cagacaatcc ggtcgtgtac cgactgataa tcctacgaca cctggtaaat tgactacttg
     1381 ctcaaatcgt tctttgatta tttcaactgg cgcatgggtg tttgtaaaat tttggaaata
     1441 aacgatgtat tgttggacat gaggccattt ttgatgcatc atgtcgattt ctttctggaa
     1501 ttggattgga agagggtctt caggtgcaac gatcatgtct cccgaaccag atacactgca
     1561 aaaagtacaa ccgccatggg caacagtccc atctcgattc ggacagtcaa atcctccatc
     1621 gatcggcacc ttgaaaattt tcccgccaaa ctcatttcgt aaagcgtaat tccaagaatg
     1681 atatctttta tttccttctg aataaggaaa agtcattaaa agtccttctt tctgtaagag
     1741 ttatctattt gttttctttt ttctctatac actggataag tcaggcacag ccaagaaaga
     1801 ctgagtaagt agccgccgat gatatcagta ggaaaatgaa cgcccagata aatgcggctt
     1861 atcccgacac ttactataat aaacatcatc agcaattgaa gcaatgtgcg taaggttctt
     1921 ttttgaacaa aagctggaag cagaaatagt aaagaaccgt aaagaatcat actgcctgct
     1981 gcatgtccac tagggaaact gtaacttgtt tcaactacta agtgcgccaa tgaaggacgc
     2041 tctcgcatga aaaatagttt gatcaccggg ttgatgattc cagcaattac aataaatcca
     2101 gaaacgaacc aaaatgtttc tgcccttttt ttcttatacc acatccataa agccgcacaa
     2161 gcaaataaaa tgatgacggt aagaggatta ccgaatttag tcataaagag ttggtagctg
     2221 ttcagatcag gataagaagc tctgacaatg cctgtaaacc actgatcgaa accagaaagc
     2281 cacgacagat ggaactttac gatccagccc aaaatgaaaa acaggacaag aaagaagcta
     2341 ccagccacct gaaatgatgt tttatatttc atacaattcc tcctttgaag caatgactta
     2401 ttatagcatt tttggtccag cgaaaaaaac ggtaaagaga taaaaccaat gtatgattcc
     2461 tctttgaata accaatattc ttataaaaaa aataactgta atcggaaaga cattttttgg
     2521 taatgcaaat gaaatgttag ggaaataaaa tcagtgtttt tcgaaatcct tttaaacaag
     2581 aacgtagacg taggaagaac ttgaaaatga acagaagttg ttcattacgg taaattacaa
     2641 tatgattaca aaaaacaaca aagctcttaa ataactttta ataaatatta agagaagtta
     2701 taattattaa taatagataa attgaagttg gaggatagaa gatggaaaac attgcaagaa
     2761 aagaacggag acgtttagaa cagaccaaac gttttcgaaa agcaaaacga ggggcagcaa
     2821 tcgtgggaac tgcgatggta ggctgttctg tcgctgcccc attagtacag ccggttcctg
     2881 ttcaagcgga tgaaacacct gttcagttcg gcgcaagaat caatacagcg gcatttatca
     2941 cagaaattgc tacttatgct caaccaatcg ctcaagccaa cgatctatat gcatcagtga
     3001 tgatcgcaca agcagttgta gaaagcggtt ggggcagtag tgcgttatct caagcacctt
     3061 attataatct ttttgggata aaaggcagct atcaaggaca aaccgtctac atggatacgc
     3121 ttgaattttt aaataatcaa tgggtaaata aaaaggagcc tttccgacaa tatccttctt
     3181 ttgctgaatc tttcaatgac aatgcctatg tacttagaaa tacttcattt ggcaacggtt
     3241 attactatgc cggtacttgg aagagcaaca cgaaatccta tacagatgcg acagcttgtt
     3301 tgacagggcg ttatgcgact gatcctggtt acgcaggcaa attaaataat atcatcgcaa
     3361 cttacggatt gacccaatat gatacaccag ctagcggaaa cgcaggcggt ggagcgacta
     3421 caggtggcaa taatactgga agtgcaggta gtactggcgg ttcaagcaat tctggtaata
     3481 caaactcagg ttcagcaact tcgaccactt atactgtcca atctggtgat tctgtttggg
     3541 gaatctcaaa taaattcggt atcacaatgg atcaattgat ccaatggaac aacatccaaa
     3601 acaatttcat ttatccagga caaaaactga caatcaaagg tagccaggaa aatggctctt
     3661 cgacgaataa ttccggtaac aataccaact cttcaggaaa tgctggtaca tcaaacggag
     3721 gacaaacaac tggtgcgaaa tacactgttc aatctggtga ttctgtttgg aagatctcaa
     3781 atgatcacgg aattacgatg gctcaattga ttgaatggaa caatatcaag aacaatttcg
     3841 tttatccagg acaacagcta atcgtatcaa atggcggttc ttctaatgct ggagcaaata
     3901 ctggctcaaa tactgggaat acaagtggct ctagttcgtc cagctcaagt tcttctaata
     3961 cagcttcagg aacgaaatat acagttaaag ccggagactc tgtttggagc gtctcaaata
     4021 aatacggaat tacgatggct cagctaatcc aatggaacaa tatccaaaat aactttatct
     4081 acccaggaca acaactgact gtttcaaaca gtggatcaac aaacagcacg tcaggtaata
     4141 caggttcgtc aaccaataca aataacagca gttcagttaa tactggcagc agttcgtctc
     4201 aaggcactta taccgtgaaa gcaggtgaat ctgtttggag cgtggcaaat aaaaacggca
     4261 tcacgatgga tcagttaatc gaatggaata atatcaaaaa caacttcatt tatccaggac
     4321 agcaattgat cgttaaaggt ggaacttcgg caaatacaaa tacaggttca actacttctg
     4381 cagcgaaacc aaatacaccg aatacgtctg ctacgacaag tacatcatcc actggtaata
     4441 cgatgtatac cgtgaaagcg ggcgagtcag tttggagcgt agcgaacaaa catcatatca
     4501 cgatggatca gttaatcgaa tggaataata tcaaaaataa tttcatctat ccaggacagc
     4561 aagtgattgt gaagaaaggt tcatctcaat caacaaacca acaatcagtt actggttcga
     4621 aaacctatac tgtgaaatct ggagaatctg tttggagtgt tgctgacagt catggaatta
     4681 caatggctca actaatcgaa tggaacaata ttaagaacaa ctttatttat ccaggtcaaa
     4741 cgttgattgt agctaaataa aatagctgtt cgaagaaata acgattgaat tccacaaaaa
     4801 tatttgttac tataaggcta cttaaatatg acaacacttg aaaaggaagt agtaaaaaga
     4861 ctgaagtttc agagagcgca tggctggtga gaatgtgcac ggatgctttt gaactcgcct
     4921 ttgagttgcc cttgctgaat acccgagtaa gcaagcggcg gtgacggccg ttacaacgtt
     4981 cgaggccttt tcactaaggt aaaattaggt ggtaccgcgt agattacgtc ctataaaaag
     5041 agcaatcttt ttataggatt tttttatttc ttttgtgaag tttgagaaaa caaagcaaaa
     5101 ggaaataaaa ataaacagat tctgccggtt ttttcgttat atttataata gaaacaagtg
     5161 ttttcaatag aacaggagga cagcaaatga gttacaatca taaagaaatt gagaaaaaat
     5221 ggcaaaaata ctgggcaaaa acgaatactt tcaacaccca tgatgatcct gaaaagccaa
     5281 aattttacgc actggatatg tttccctatc catccggtca agggctacat gtagggcatc
     5341 ctgaaggtta tacggcaacg gatatccttt cacgtgtgaa aagaagtcaa ggatacaacg
     5401 tgctgcatcc aatggggtgg gatgcattcg gtctgcctgc tgaacaatat gcgctagata
     5461 caggaaacga tccagctgag tttacccaaa aaaatatcga aacattccga cgccaaatca
     5521 attctttagg atttagttat gactggaatc gcgaagtgaa tacaactgat ccggagtatt
     5581 ataaatggac acaatggatc tttacgaagc tttatgaaaa aggtctagct tatgaagcag
     5641 aagtagcggt aaactgggta cctgaattag gaacagttat ttcaaatgaa gaagtgatcg
     5701 atgggaaaag tgaacgtggt ggctatgatg tagtcagaaa accaatgcgc caatggatgc
     5761 tgaaaatcac tgcttatgct gatcgcttat tggatgatct agaattagtt gattggccag
     5821 aaagcattaa agaaatgcaa agaaattgga tcggtcgttc agtaggagca aatattgaat
     5881 ttaaagtggc tggtacggat aaatcctata ccgtatttac gacacgacca gatactctat
     5941 tcggtgcaac ttactcggtt cttgcacctg aactagatct tgttagagaa attacgaccc
     6001 ctgaacaaaa agctgctgta gaagcttata tcgaagagac agctaaaaaa tcagatctaa
     6061 agagaacgga tcttgcaaaa gaaaaaacag gagtatttac tggtgcttat gcaatcaatc
     6121 cagttaatgg caaggaaatc ccaatctgga tcgccgatta tgtattatct tcatacggca
     6181 caggagccat catggctgtt ccagcacatg atgaacgtga ctttgaattc gctcaaactt
     6241 tcggactaga aattcttcca gttatcgaag gtggagatgt tgaaaaagct gcttacacag
     6301 aagatggtac gcacatcaac tctgaatttc tagacggcat gaacaaacaa gaagcaatcg
     6361 ataaaatgaa tgaatggcta gaagaaaatg gcgtagggaa aaaagaagtc agctatcgct
     6421 tacgtgactg gctattctcc cgtcaacgtt actggggtga accaatccca atcatccatt
     6481 gggaggacgg aacagtcaca gctgtcccag aagaagagct accattacgg ttgcctaaga
     6541 caaaaaacat caagccaagc ggtactggag aatctccatt agcaaatatc gaggagtggg
     6601 tcaatgtcgt tgatcctgta acaggtaaaa aaggccgtcg cgaaacgaat acaatgccac
     6661 aatgggcagg aagctcatgg tattacctgc gttatatcga ccctcataac aaaaaagaac
     6721 tagcagatta tgaaaagttg aagcgttggc taccagttga catctacatt ggtggagcag
     6781 aacatgcggt acttcattta ctatatgcac gattctggca taaattctta tacgatatcg
     6841 gtgttgttcc tacaaaagaa ccattccaaa aactatacaa tcaaggaatg atcttaggcg
     6901 aaaacaacga aaaaatgtca aaatctcgtg gtaatgtagt caatcctgat gatgtggtcg
     6961 aaacttacgg tgcagataca ctgcgcatgt acgaaatgtt catggggcca ttagatgctt
     7021 cgattgcttg gagcgaaaat ggcttagaag gaagccgtaa attcttggat cgtgtatggc
     7081 gtttgatcgt tgatgagaac aataaaatgc gtgaccgtat cactacattg aatgatggca
     7141 agcttgataa agtgtatcat caaacagtga aaaaagtgac agaagactat gaaaatcttc
     7201 atttcaatac agcaatctcc caattgatgg tctttatcaa tgaagcctat aaagtggacg
     7261 ctctgcctta tgaatatatc gaaggatttg ttcaactact cgcaccgatt gctcctcaca
     7321 tgggtgaaga actatgggca atccttggaa atgatggtgg tatttcttac gcaccatggc
     7381 caacatacga tgaagcagca cttgttgaag acgaagtaga agttgttttc caagtaaacg
     7441 gtaaagttcg tgcgaaaagc aatgttcccc gagacttagg aaaagatgag ctagaaaaag
     7501 cagcattagc caatgaaata gtgcaagaat atattgaagg caaaacagtc agaaaagtta
     7561 ttgcggtacc aaacaagtta gtcaatatcg ttgctaatta attggctctt tgtcaataag
     7621 gactgatgag ttgtgcaaaa tcaaatctgg gccagaatga acttcattct gtctcagatt
     7681 ttttgttatt tcaaattgat taattgattg atcaaaaagg ttttgatttt catgttctca
     7741 aacacgttca atgtcttttt cttctgaatg gtcttgtaag agatctctgt aatcatcaaa
     7801 tttttgtcta ttaatcttag tattttttga tgtataaact acctgaaatt gagagtacat
     7861 accaaattca taaatttttt attagtggga ctagtgattg tatggatttt gacgcataat
     7921 gaatgaagta tgagaaaagg agagacaaat ggatcaagaa ctatttatta tcgaagtatt
     7981 atcagctaaa caaaaaatta tcgagaaagc gaaaaaaaga gcgaaaagaa taatgttcaa
     8041 gcttttaagc ttagtatttt tctctggttt gctttttttc ggagctgtat cgttcctata
     8101 tcgccatatg agtgcagtag tccgttcagc tgaagggatg caaaaattaa ataatttgta
     8161 tcacttttcg tggggagttg gcggaataac aattgttgtg cttattgttt ttcttctact
     8221 tatttggctc cgttaccatc aattgtcgcg tcatttcgat caatggctta gtcaaagagc
     8281 acaacagttt ttacataata aaccaacttc tcaagatgat gactatcttt attttgagaa
     8341 gacttcgacg agtcaagctt ttcggataca aaaaagtgat tgccagttat tgctgagatc
     8401 acttgatgat ttacctatct acttaggcga aagcaaatca aaattcggaa tgaacacatt
     8461 ccatattttt ttactagaaa acgaacccag atgggaaaaa agccagtctt cgcctggtgg
     8521 atacctgaca actaagatga gtacattagt cactggtttt ttcctcattc ttttagctgg
     8581 aacaatctat tatgggagat acactcagcc aaaaatgtct tctcatataa atgctgcttc
     8641 tcacatgaca atgaactcaa ctaacgatac gcatatacaa aagacaaatg aagggttgtt
     8701 agctgatcct aagcaaaagg taaatttgac aacacaaaag ataaatgatc tcaaacttga
     8761 tacagagacg cactctctct atatgacaac agatagtggt gctaattggg tatttgtgcc
     8821 gattgattcg caatggttgc gttttggcga atacaccctg acaacggggc tgattcctga
     8881 aggttattgg atggacaaca catatgatat ttccgccgat ttctcatggt ttatctattc
     8941 ttctggggat gatgtacgtc tgctgacttc aagagataat ggtaaaacat ggcaaacgtc
     9001 tattatcacc caatcagttc agccgatacg ttatcgaaaa gcggtatttt atggcaacga
     9061 tggtctattt atctgtacat cagccagtgg gatgtctgca gaaactttgt acatttacac
     9121 tactatggat ggcggaatca cttggataaa aagtggaagt acaatgatca atcagccagt
     9181 acaaaatgtc agcttcgtta caacttcttt aggttttgtt tcgacacgtg aaagtttgtt
     9241 ttatacaaac aacggaggac gctcattcaa agaatcagtt ctgtcgattc cggaaaacta
     9301 tcagacaggg gggatagatc tttttcaatc accaaatgaa gttactcaaa taagcgcgaa
     9361 tacgttagag acaaaatttt atttgttgaa aaaaggacca atcgatgcag ggaaaatgtt
     9421 tgcctgcctc ttccgttcaa ctgataacgg ggaaacatgg caattcgttc agcaactatc
     9481 gcaagtagaa caaggagatt aaagaagaga gattgtgagc ctgacgttca gcaccgagtc
     9541 acaagaaaca aattcaaaaa acagcttctc atatttgttg aatagtgtaa ctcgtgattc
     9601 ggagttgaca agagcaacaa gaagcgattt tgaagtatag cttctcgtat tttacaagat
     9661 cgtgtcttat tgccgatagg ttgtctcttg aacaccgttt attcgtaaaa agggattgtg
     9721 acaagtcttt tgtcactact taccgaacga aactgaagga gctatccaaa aagtatcatt
     9781 agtattattc tttgtgtttc tagtggcacc actagtacat ttaaaaaagc tatcgatcat
     9841 ggactaatca tacatgatcg atagcttttt agataatgtt tgttacgcta tctgaaattg
     9901 actattataa agactggcat aaagcgttgg tgattggagt agttcagaat gtgttccttt
     9961 ttcgacgata tcgccattct tcattacaag gatcatgtct gcattttcaa tcgttgacaa
    10021 acggtgtgca atcacaaaac ttgtcctatc ttttgtcaca gcttccattg cttgctgaat
    10081 caatgcttct gttcgtgtat ctacgctaga agttgcttca tctaaaataa cgacaggagg
    10141 attcgctaga atgactcgag caattgtcaa taattgttgc tgtccttgag ataacgtgcc
    10201 gttttcgcta gaaatgatcg tatcatatcc gtctggcagt gttcgaataa agtgatcaca
    10261 ttgtgcgatt tcagccgctt cgataatttg ttctcttgtg gcatccattt tcccgtaggc
    10321 gatattatca gctaccgttc cttcaaacag ccaggtattt tgtaaaacca tcccaaaaga
    10381 acgacgtagt tctccacgtg aaagcttggt aatatcaaga ccgtcgaatt cgatctttcc
    10441 tttattcagt tcataaaaac gcatcagcag attgactaaa gtcgtttttc ctgcaccagt
    10501 tggaccaacg atcgctaccg tttgttttgg ctttactgaa aaatcgactt gattcatcaa
    10561 tattttatct gatgtgtaac caaactgtac atttttgaaa gctatttttc ctttcggttg
    10621 ttctaaaagt cttgcatctg gaaggtctgg aatttcatct gtttcatcta atatctcaaa
    10681 tatcctatcg attgctgcca ttgcggattg gatcgagttg atcacataag aagcggtaga
    10741 aattggttca gaaatctgat tgatgtactg aagataagct tgtaagaagc cgatcgtcac
    10801 accacctgat agaacaagca tagcaccgaa taccgcactt atgatgaagg cgagttgatt
    10861 aatgaaacga atggccggat agatagcaca gttcataaat tgagcacgtt taaaagcgtt
    10921 gtattgcttt ttatttactt cgtgtatagc agcttctgca tgagcttgct gattgaatgt
    10981 tttgaccact agattaccag ctaagatttc ttccattcga ttatttaaaa cacccagttc
    11041 atactgattc tgttcagaaa tctgtttgtt tttgttcgca atcttagttg taacaattga
    11101 actgccaacg atcagcaata agacgagcaa agtaagcttg ctttcgatat aaaacagcat
    11161 cagaccagca gcagctattg ttacgacaga agtaaaaaat tgattgatac ctgtcaataa
    11221 cacttgagaa agttgattga gaccggtagt tgtccgacta atgatgtcac ctacttgatg
    11281 attgtcaaaa aacgacatcg gtaatgtttt gaattttttt gtgatttctt ttcgcaccct
    11341 caatgtgatc ttttcgctta acgctgccat tgtccgttcc tgaataaatg aagtgatgct
    11401 gcttaagact gaacagccga tcagcaataa gacagggaac aacaatgctt gtttgatatc
    11461 actgaaagaa agctgtccaa tacctgtttt tcttatttct gataagagat catcgatccc
    11521 gattcccatg atcaagggca tggctacgac taataggttc ccgaataaac tgcatagaaa
    11581 caatccgtaa aaatatttat gttcaggttt gatcattttc caaaaacgta tcaaagcacg
    11641 cgtgttcaac gtttttttct tttccatcgt atcccttctt tctatattcc ttgtgatttt
    11701 gcaaactcct gataagtttg gcaattagac agtagttctt catgagtacc ttgtccaacg
    11761 atttttcctt catctaaaac aatgatgtta tctgcttgtt ggattgtact gaggcgttga
    11821 gcaacaatca cgagagtttt ctccgacatg tgtttatgaa gggctgctct taatgctgca
    11881 tctgttttat agtctaaagc ggagaaacta tcatcgaata catagatctc tgctggtttg
    11941 atcaacgctc gagcaataca tatccgctgt ttctggcccc ctgaataatt agaaccgcct
    12001 tgagcaacaa agctgtccaa tccgtcagga agggtgtcca ctagttcttc taattgagcg
    12061 atcttgatcg ctttagacaa ctcttctgtt gaggcatatt catttcccat ctgcaagttg
    12121 cttaaaattg tcccgctgaa taagaaagcc ttctgaggga cataactgat gtgggagcgg
    12181 atctgttctt gagtcatttg agtaagagga ataccaccaa gggttacttt tcctatcgta
    12241 gggtcactaa gtctcaagag aagtttcgcc aaactacttt ttccagatcc ggtcccgcca
    12301 acgatcgctg ttgtttttcc tttaggtatt gtgaaatcaa tatcttctag aactggatca
    12361 gagatttcag tatatttaaa tgtgacatgt tcaaaagcag ctgcatttgt ctgatcaaag
    12421 gttggttcag ctactgtttt gatcgtctct tcctcaattt cgatctctgc ttgcagtatt
    12481 tcttctatcc gtcgtaatga ggcaaacgat ttagggataa tgaccaatac catagctgcg
    12541 atcatcaagt aagcaagtgt cagcatagag tattcgacta cagcagtcac gacaccgatt
    12601 tgtaatgctc cttctgctac aagatttccg ccaaaccaca aaatagaagc ataaacgatt
    12661 cccatgagca aaaaagcaat tggagtgacc caagcaaata ttcggttcac tttgatcatt
    12721 tgattagcat agtcagcaaa gctcttattc gttcgctttt cttcatatga ttgattatca
    12781 aaggcacgga tcatattaat cccagtaaag aattctctca atgtgatggt gatccgatcc
    12841 atttttggct ggatactcaa agataaaggt gcccctcgtt tcatcagtcg ataaacaatc
    12901 catacataaa aaacaacaga gatcaatgta acccatgtta gtaatagaga ataacgaaac
    12961 atcatgagaa tggtgaaaac gcaaataacc ggtgctggta agatcatttg gcaaaataaa
    13021 acaatcattt gctggacatt atcgacatca ttcgtcattc ttgtcaaaag agatccagaa
    13081 ctaaaacgac tgatatcctt cattgacagc tgttggaatt tacggaaata tttctcccgc
    13141 gtttggaatc caaacctagc ggaagccaat gctgaaaagt aactagaggc aactgcagcg
    13201 attgttccta gaaacgctac aagcagcatt tcaactccaa ttttttttat aactgaggct
    13261 tcgccacttg ctatacctgt gtcgatcagc tttgctacta attttggtac acctaatgta
    13321 ccggcgattt ctaaacagat catcacaaag gtaaggagag cgagtccttt gtttttctgt
    13381 aagaatgttt ttaagataga catattattc ctcctttttt cctgatactt ttcgattcta
    13441 taccttcaag taacttgaag gtcaatagaa aaaagaataa actgaaaaag aggtgagaaa
    13501 aaatgaaaaa aatgtatacg attggccaag tatcggaact atttgatttg ccaaaatcaa
    13561 cgatccgcta ttgggatgaa caaggattaa tccgttcaag tagacaagaa gagaatgatt
    13621 atcgattgtt tgatatcgat gatattttta tgctttatga tatcgttttt tatagaaaat
    13681 tagatatacc gatcaaacag atgaagaatt tatatggaaa aacattgacg gagttatatg
    13741 agacacttga tgaaacagaa agaagaatcc ataaagaact ggtggtgatg aaacaaaaac
    13801 aaaaagagat aagggagcaa aaaaaacagt tgaaattgat gatcgataca aacgaggaag
    13861 aatttcctgt agaagagatc ccttttgact gtatgatctc aacggagttt gaagatattg
    13921 tggaaatcaa aaaatttcta cctaactatt caagctttgg gatgatgagt atgccagctt
    13981 ccagttcaca gacgatgtat ggatttttta tcgaccctag tgaagtacat ttatttactc
    14041 aagacgtgat ttgggagaaa aaagatacgg ctgtttatcg tcgattctta ttgaaatccg
    14101 agatgaacca tgcggaacgt aataatattt tagaaatcag agaaagaatg tatgaaaaag
    14161 gatggaaaac aggagaagtg atcggccagt atctattgac gaatacggat gaaaacaata
    14221 tcagaactga atattatcat gcatggatag aaatgaaaaa ataggaaata tgtgtttaag
    14281 ataactcgaa aatgatggtt gttttagtta taaagaaaaa ttttctggtt cgattacggg
    14341 tttaatgtgg gggattatta gtcgtggata gatagaattt tagtttttta gaggaaatat
    14401 gtctttaaaa atggaatggt tgcaattctt agcgatatat acgatgtaat tgtcctctta
    14461 aaaaagtatg gaaaaataat tgtattgggt gttatgtata attcatggtg aactgagact
    14521 aatgagaaga aaaattcata ttgttatgag tgagattgta tcagatgaga atgataaatt
    14581 aaataggtgc ataaaagcat tacacttaaa atacattgtt gcttacatta ttacaatatg
    14641 ttaataaggc aaaaataaat agatggattg aataaacata ttttttaatc aaatagtccc
    14701 tactgtgact ttcctcagct atcggtgata ctaccgatag catttttt
//
LOCUS       DADVXM010000062        14616 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.065, whole genome shotgun sequence.
ACCESSION   DADVXM010000062 DADVXM010000000
VERSION     DADVXM010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.065"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..611
                     /locus_tag="KB927_001985"
     CDS             <1..611
                     /locus_tag="KB927_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBB6840895.1"
                     /translation="EKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRM
                     YSGDDNGVDLYKFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSS
                     FKKMFKSRDGITLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLL
                     YVICSRAKNNLFLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            811..1125
                     /locus_tag="KB927_001986"
     CDS             811..1125
                     /locus_tag="KB927_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6840896.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            1146..1523
                     /locus_tag="KB927_001987"
     CDS             1146..1523
                     /locus_tag="KB927_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6840897.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            1533..2306
                     /locus_tag="KB927_001988"
     CDS             1533..2306
                     /locus_tag="KB927_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840898.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            2328..3731
                     /locus_tag="KB927_001989"
     CDS             2328..3731
                     /locus_tag="KB927_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBB6840899.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            3913..5097
                     /locus_tag="KB927_001990"
     CDS             3913..5097
                     /locus_tag="KB927_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBB6840900.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            5094..5384
                     /locus_tag="KB927_001991"
     CDS             5094..5384
                     /locus_tag="KB927_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840901.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            5381..5602
                     /locus_tag="KB927_001992"
     CDS             5381..5602
                     /locus_tag="KB927_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840902.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            5644..6423
                     /locus_tag="KB927_001993"
     CDS             5644..6423
                     /locus_tag="KB927_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBB6840903.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            6490..6984
                     /locus_tag="KB927_001994"
     CDS             6490..6984
                     /locus_tag="KB927_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBB6840904.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            7040..7678
                     /locus_tag="KB927_001995"
     CDS             7040..7678
                     /locus_tag="KB927_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840905.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            7750..8145
                     /locus_tag="KB927_001996"
     CDS             7750..8145
                     /locus_tag="KB927_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6840906.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            8129..10582
                     /locus_tag="KB927_001997"
     CDS             8129..10582
                     /locus_tag="KB927_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6840907.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            10579..12606
                     /locus_tag="KB927_001998"
     CDS             10579..12606
                     /locus_tag="KB927_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840908.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            12603..13625
                     /locus_tag="KB927_001999"
     CDS             12603..13625
                     /locus_tag="KB927_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBB6840909.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            13642..14571
                     /locus_tag="KB927_002000"
     CDS             13642..14571
                     /locus_tag="KB927_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6840910.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
BASE COUNT         4974 a         2444 c         2896 g         4302 t
ORIGIN      
        1 gtgaaaaggt tcgaagaaga aagctaattg caaacgatat tttaattata ttaaaaaatg
       61 aatttggaat agaagttaaa gattatttta ttgacttaga tttattacag ctaataaaca
      121 gtgtgaaaag aatgtatagt ggagacgaca acggtgttga tttatacaaa tttgttacca
      181 aacatatatt tgttaatctt aatattgacg agaaaaatta cccgtctatt tttaagcact
      241 atctattttt tattaacgaa gtagaagatc ggataaaaaa taattcatta tctagtagtg
      301 tatctagttt taagaagatg tttaaatctc gagatggtat cacacttact acagcacata
      361 aagttaaagg aaatgagtat gatactgtta tcgctattaa tcttctaaac gggaaaattc
      421 ctcattggaa tgaaattttt aatgtttctg ataaaggaat tagttcagcg agaaaactac
      481 tatacgtaat ttgttcaaga gcaaaaaata atttatttct tttctcagag gtgggttatt
      541 ttacgagtaa aggagacttg ctttatccca ctcaattatt agataaaata gaatttgatt
      601 ataatattta aaatacctag gtagtcgttg ttttaaatat agtaggaatc ggacgctcag
      661 tacggagcgt ctattttttt acccaatttt gaaaggaagt gaacttatga aaataaaaaa
      721 tcaagaatca aaaggtcgct ctcccccctt taaaaccatc acacaaataa gattcattca
      781 aacataaaaa cagaaaggat aggtaaaaat atggaactta aatatgtcat tcccaatatg
      841 gaaaaaacat ttggacaatt agaatatgct ggtgaaggga acattgaaca acgtcgaata
      901 aatggcagac caaccattct ctctcgtagt tacaatttat actcaacgat tcaacgagca
      961 gatgatattg ttgtcattct tccctccgaa gctggcgaga aacattttga atccgacgaa
     1021 aaagtcaaac tcatcaaccc acatattacc gcagaaggtt ataaaattgg caatcgagga
     1081 tttaccaatt acattatgca cgcagacgat atggtgaaag cataagaaag gaaaggtgaa
     1141 aaaatatgag attagcagaa ggtattgtga ttgaaaaaga ccagacattt ggcacattga
     1201 aattttccgc cttgcgtcgt gaggttcgta tccagaatga agatggtacg gtttccgaag
     1261 aaattaaaga acgtacctat gacttaaaat caaaaggaca aggacgcatg atacaagtca
     1321 gtatccccgc ttctgttcct ttgaaagaat ttgactacaa cgcagaagtg gaattaatca
     1381 atcctgtggc agataccgta gcgacggcta cttttcgagg ggcagacgtt gattggtacg
     1441 tgaaagcaga cgatcttgta ttaaaaggac agacaaaacc tcatcagaaa tataaaaaag
     1501 aagcgtccga aagtgaaaaa taggtgttgc ttatgacaaa cacaccattg attttgaaag
     1561 aaattccgaa ggatgaagcc atttctttta ttcggcaata ccattattca aagatactcc
     1621 ctagattgtg taaatacttt ctagggattt tttcagaaga aaaattatta ggcgttgtgg
     1681 aattaggctg gggtacgcaa cccctacaaa ccatacgcaa actctttccc gacagttccc
     1741 ttcaaaccac agattattta gaaattggaa agatgtgttt tcttccagaa atgaatcaaa
     1801 ccaattattt tggcagtcaa gctctttcag ctctaattaa gtggttgaaa gaacatacgg
     1861 actgtcattt tttatataca ctggcagatg gaattgaggg aaaatgtggc tatgtctatc
     1921 aagcgtccaa cttcttttac tgcgggtatt tcaagacaag tgtctatcgt gataagcagt
     1981 catgggaaaa gatacaccct cgaagtgctc gccttttatt agaggaaaat gctcgctttg
     2041 aacaggtaga gaaaaagcat tggctttccc aggcattttg cgaatacaaa gggattgaga
     2101 aaatcaatgg acgcatgttt cgctatctct atccgttgac aaaagaagcg aaaaaactgt
     2161 taggacacac tctctatcga cgtcattatt atccgaaaga aaaaaattta cgctttgaaa
     2221 agcgaatcgc ttatcagaaa tatgaagcca tttctcaacc aacttttgat aaacaggctc
     2281 gtatctacaa tacacaatta ttttgatagg tggaaaggag gatttttatg ccattgcttc
     2341 atgacagagg agagcgaatc aaagccaacg ataagcactt ggtctatcat tttgtactaa
     2401 tttcattgct ggtagttttt ctagtcgtcc tactcccttt tcattggaga gcgttacaat
     2461 cggtgaactg gcaagcagtt cagttagata catttttcta tcaacttcat acgccatact
     2521 tttggagcag tattctcact gctctttttg tatgcggact tatcagctgg ctttattatc
     2581 actatcgtat agattctata aaacagttag agcaccgtca aaagttagct cgtatgattt
     2641 tagaaaatca ttggtatgaa gccgaagaaa ctcaatcaga gggattcttt aaagatttac
     2701 ccagcaagaa aaccaaacaa cgaatccgcc attttcctaa aatatattat cgaatgaaag
     2761 atggactaat ccatattcat gtagaaatca ccttagggaa atatcaagat cagcttttgc
     2821 acctagaaaa caaactagaa acaggattgt attgtgaatt agtggaaaaa acgttgaaag
     2881 attcttatgt agagtatgtc ctactttatg atactattgg caatcgaatt ggcattgaag
     2941 acgtggtagc tcaagatgga cgtgtcaaat tgatggaatc ggtctattgg gagttcgatt
     3001 ctctccctca catgttaatt gctgggggca ctggtagtgg aaaatcctat tttattctca
     3061 cattgattga atctctcctg catacaaatg caaagcttta tattcttgac cctaaaaatg
     3121 ctgatttggc agacttaggg gcggtcatga ataatgtcta ttaccgtaaa gaagatatgt
     3181 tggcatgtat caatcaattt tacgaagata tgattgatcg cagtgaaacc atgaaacaac
     3241 accctaacta taaaacagga gaaaattatg cttatcttgg tttgtctgcc aattttctta
     3301 tttttgatga atatgtggca atgatggata tgctaggtcg tgaaagtacc accgttattc
     3361 ataaactcaa acaaattgta atgttaggac gacaagcagg cttcttttta attcttgcct
     3421 gtcaacgtcc agacgcaaaa tattttagtg atgggattcg ggacaacttt aacttccgtg
     3481 tggctttggg tcgtatgtct gaaatgggct ttggtatgat gttcggaagc gatacacaaa
     3541 aacaattttt cttaaaaccc atcaagggaa gaggttacgt ggatacagga aaaagtgtga
     3601 ttagtgagtt ttatacaccc cttgtaccaa aaaggtacga tttcttagga gaaataggaa
     3661 aagtcattca aaaaaagcaa tctgagcctg taccgcacga agtgaaaggt acaggttcag
     3721 acttgctttg attggtgtgg cgttagccac gccaatcctt tagccccctc tatctaacag
     3781 gggggcacaa atacaactga aaacaggcaa ttctcatcaa ccaatgttga tggtacaaag
     3841 gattgcggaa aatatgaaag gtgtaaactc aagggtcata gtttacatct tttttagatt
     3901 ggaggtttgc gaatggaaaa cgaaaaaatt tggattaagg aattgaaaga aaagcgactg
     3961 gcttatggcg tttctcaaaa taaactggcg gttgcttctc atattaccag accttaccta
     4021 tcggatattg aaacaggcaa ggcagtccct actcaacagg tgaaagaaga tttactgaac
     4081 gctttggaac gcttcaatcc cgataaccca ttggagatgt tattcgacta tgtacggatt
     4141 cgattcccta ccaatgatgt ggctcaaatt atcggtgagg ttttacgttt gaatatggat
     4201 tatatgctac acgaagactt tggctattat tcttatcccg aacactatcg tttcggtgat
     4261 attgttgtcc tagtctctca tgatgtaagt aaaggtgttt tattagaact gaaaggaaaa
     4321 ggctgtcggc aatttgaaaa ctttctattg gctcaacatc ggagctggta tgatttcttt
     4381 caagattgca tggaacataa aggtattttc aaacgcttgg atttagctat caacgataaa
     4441 acagggattt tgaatattcc agatttggca aagaaatgta aacaggaaga atgcatttcc
     4501 gtctttcgaa gctttaaaaa ttatcgcagt ggtgaattgg ttcaccgtga tgaaaaacca
     4561 tacatgggaa acacacttta tattggctca ttaaaaagtg aagtctattt ctgtatatat
     4621 gagaaagatt atgagcaata cgtgaaaaat gatgttccct tagaagacgc agaagtaaag
     4681 aatcggtttg aaattcggtt aaaaaatgac cgagccaccc aagccatgaa agatttattg
     4741 gcacatcaac aggcggaaaa aacagccttt gaaattatca atcgctatat ccgctttgca
     4801 gataaagacg acactaaacg tcggagtgat tggaaaacta atgaacgttg ggaatggttt
     4861 atcggtaaaa atcgtggagc attacgccta accacacagc cagagcctta ttcttttgaa
     4921 cgaacattga actggttaca tcatcaagtc gcccctacat taaaaatcgc aagcatttta
     4981 gatgttctca acggtacaac cattatctcc accatgattc aggaagccaa actgacagaa
     5041 aaacatgaga aattaattga acaacaacat ctagccatgg aggatttgat tacatgagcc
     5101 ttttaacaaa agaattaaag aagttagggt ttcagtgtgg cattgagttt caagcgtata
     5161 tacaaaatac agggaaatat acgtctctca ttattgaggg aaaacggcaa gctggtgata
     5221 ccatctatac ctatgatttt tacaaggtga gattttataa taattatacc aatcgagtaa
     5281 ccgtctatgg agagcattta accccttttc aattattaag gcgtgtaaaa agctatatct
     5341 attatcgaga aaaatatctt aaggaaagga ggacaatcac atgaattttg ggcagaattt
     5401 gtacaactgg ttcttggata atgcacagtc attggtattg ttagcgattg ttgtcattgg
     5461 actgttttta ggttttaaac gagaattttc aaaactcatt ggcttcttga ttattgctct
     5521 aatcgccgtc ggacttgtgt tcaatgcagc tggcgtgaaa gatgtgttat taaacttatt
     5581 taaccgaatc attggtgctt aacagatatt tttcatgata aaataggaag tatatatttt
     5641 gttatgaaag gatttatgaa tatgtttaca aatgatcaat ttaaatctct tttaattaaa
     5701 acattagaaa gaaagagctc ttcaaattat tatgaaggag gtaacgagat tgtttctaaa
     5761 atgaaaatat cagaggtaac tttagatgag actgacgatt ttacttatta taaaggatat
     5821 aaaaagggct ggaatacgct ttgcacatat cttaaaataa gagttccttt tgatgattta
     5881 gacttttttg aaagtcataa agatttgatt acccagacag caagctccat atatgataaa
     5941 caaggtgata atgtattagt ggatactatt ttagtaccac ttccagagaa ttacgaagta
     6001 attaacttta gtcagttgaa aattagtgat gtggtttcac aagctattga agacgctgag
     6061 tcttttatga gtaatggtga atatcaacgt gcctttgaca gagttcacac tgcttttcat
     6121 ggatatttaa ttgaaatact aaaaaaatat gaaattacag ttcctagaga cgaaaatcta
     6181 tctaaattat atagtaggat acaacaatta attgaaaaag aaattcaacc tactgaactt
     6241 gctgatatag tgaagacaac gataaggtca tcaaatggaa tgattagctc tcttaatgaa
     6301 gcaagaaata ggcattcact tgcacaccct aatacaaata ttattggaaa gagagaagca
     6361 aaactaataa taggtatttc aagtacagtt acagattata ttagcggata ccttgataag
     6421 tagcgtcatt aactgattgc tacttttttt atgactattt ttataaaaag gatgtgataa
     6481 gaattggaaa tgaaagtcta tgtggcaaat ttaggacggt ataatgaagg tgaattagtc
     6541 ggagcatggt ttactccacc aattgatgag gaagaaatgg cagaaagaat cggtttaaat
     6601 gaggactacg aagaatatgc aatacatgat tttgagcttc cttttgatgt ggacgaatac
     6661 acgccgatta gtgaaatcaa ccgtctatgt gaagccattc aagaaatcga aggtacacct
     6721 atttataatg aactcaaaga aattcaaggc atgtggttta gtagcttgga agaattactg
     6781 gaaaacaaag aggatattca ttgttatagt gattgtgatt cgatggaaga tgtcgcccgt
     6841 tattacgtgg aagaaacagg acagcttggt gaagtccctt ccaatttaca aaattatatt
     6901 gactaccaat ctttgggacg tgatatggaa atagagggta attacctagt tacctctcat
     6961 ggggtatttg aatattgtca gtaagtttaa caatccgtgt tataattaaa ttaataaata
     7021 gcacggagag gtataaatta tggtaaatgt atttgaaaat cttaaactat taaaactaga
     7081 catgaaagat aaaggctggg tgatagattc cttttacttt cgttacaaac agcaaaatta
     7141 tattgtactt gttaagctat ttgaaaaaga ggaaaaagtt ccagaatatg ctctgttaaa
     7201 actagaattt ttaaaggaaa acgatttttc agatatgcta gctgtctatg ctaattcggt
     7261 aaaattatat acagacacga aaacaataag agaatatttt ggtatcgaat acagtagtaa
     7321 cttgggagat gttttatttc aatttagcca aactcttgct cgatttattc cgacagaagt
     7381 tagtgagaag aaaaatgaag accaaaaaga agccatgtgt ttctcattaa gtcaaagtga
     7441 ttcagaagat cccagaaaaa aatattgttt ttcagttaga agaaatcctt taaagggaaa
     7501 tggtgagctg ggaaaacgaa gtccttttaa tgacaataaa acgagattgt atagacccag
     7561 cttatatgaa cgattagggt cagataccaa tttaagtttc agatattcaa tgaatccaga
     7621 tgatgaagaa actgatgaag gtattattgc aaaatggaca aaaaataaaa ttgaatagtt
     7681 aaagcattga aagagcaatc acctattttg attgttcttt ttctattttt acggaaagga
     7741 cgtgaagaca tgaaaaaaat aagaagttac accagtattt ggtcagtaga aaaagtgatt
     7801 tatgcgatta atgatttaca actccctttc ccaattacct ttacgcaaat gacatggttt
     7861 atcgtttctt tgtttgtcgt catactcttt ggcagtttac caccactttc tctgattgac
     7921 ggagcactac tcaaatactt agggattccc attgttctca ctgggttcat gtgccaaaag
     7981 acctttgacg gaaagaaacc ctatggattt ctaaagtcta tcattaccta tgctctacgc
     8041 cctaaagtaa cctacgctgg caaacaaata cgattaaaaa aagaaacaat gaatgaatcg
     8101 attacgattg taaggagtga acaactagat ggcatatccg attaaatata tggaagataa
     8161 tctcgtattt aatcatgatg gcgaagtatt cgcttattat gaattaattc cctataatta
     8221 cagtttttta agttccgatg aaaaaattca agttcatgat aatttctgtc aattgattgc
     8281 ccaaaatcgt gatggcaaga ttcatgctct gcaactagca accgaatcaa gtattcgagc
     8341 cacacaggaa caatcgaaaa aagaaatcac tggacgatta aaagagatag cttacgaaaa
     8401 aatagatgaa cagaccgaag cgttaatttc tatgattggt gacaatcaag tagactatcg
     8461 cttttttatt ggttttaaac tctacctcaa tgaacaggaa gtatccgtaa aaaatgttgg
     8521 gaaagaaatt caaaaagcat ttgcggaatt ctttcatggt gtgaatcaca aattaatggg
     8581 cgattttgtt tctatgccta tggcggaaat cgaacgcttt tctaagatgg aacagttgtt
     8641 agaaagtaaa ttatccagac gctttcagat tcgtaaattg gagaaagatg attttggtta
     8701 tattattgaa catctttacg ggcaaacagg tgtccctttt gatgactacg actaccattt
     8761 accgaaacga tacgaagata aaaaagtgtt ggtaaagaaa tacgatattc tcaaacccac
     8821 tcgctgttta atcgaagaaa atcaacgcta tttacggatt gaacaggaag ataccactac
     8881 ttatgtggcg tattttacaa ttaatagtat tgttggtgaa ttggatttcc ctaatagtga
     8941 aattttttat taccagcaac agcagtttac tttccccgtt gataccagta tgaatgttga
     9001 aattgtcgcc aataaaaaag ccttatctac cgttcgcaat aaaaagaaag aactgaaaga
     9061 tttagatagc cacgcatggg aaagcgacaa cgaaaccagt actaatgtgg tggacgcttt
     9121 agaatctgtc gatgaattag aaagtaattt agaccaaacc aaagaatcta tgtacaaact
     9181 aagctatgtg gtacgggtat cagcaaagaa tttggacgag ctgaaacaac gttgtgatga
     9241 agtaaaagat ttttatgatg atctgtctat caaattagta cgaccttttg gcgatatgct
     9301 aggcttgcat aatgaattta ttccctcaag caagcgatat atcaatgact atattcaata
     9361 tgtcacgtcg gattttttgg ctggtcttgg tttcggtgct acacaaatga ttggtgaaaa
     9421 ttctggtatt tacgtcggtt acaatctcga tacaggcaga aatatttatc tccaacctag
     9481 ccttgcaagt caaggaatta aaggctctgt aacaaatgca ttagcgtccg cttttattgg
     9541 ttcattaggt ggcggaaaat cattctctaa caatatgctg gtctattatt cagtactctt
     9601 tggcggacag gcaaccattg ttgacccaaa agctgaacgt ggtgaatgga aagaaacctt
     9661 acctgatatt gcccatgaaa tcaatattgt taatctcacg agtgagaacg acaataaagg
     9721 gttacttgac ccttatgtga ttttaaaact cccgaaagat tcagaaagcc ttgccattga
     9781 tattctcacg ttcttaacag gtatttccag ccgagatagc gagaagtttc ctgtcctgcg
     9841 taaagctatt cggagtgtaa ctcaaagcaa acaacgaggg ttgttattgg tgattgatga
     9901 attgcgaaaa gaagatacgc ccatcagcaa tagtattgct gaccatatcg aaagctttgt
     9961 cgattatgat tttgcccatc tgttattcag tgatggcagt gtcacccaat ccattagctt
    10021 ggaaaaacaa ctcaatatta ttcaagtggc agatttggtc ttacccgatt ccaatagctc
    10081 ttttgaagaa tacactacca tggaattatt aagtgtggca atgctgattg tcattagtac
    10141 ctttgcttta gactttatcc actctgaccg ttccattttt aaaattgttg accttgatga
    10201 ggcttggagt tttttacaag tggcacaagg aaaagctcta tctatgcgat tggttcgagc
    10261 aggacgtgcc atgaatgcag gggtctattt cgttactcaa aacgcggacg atttactaga
    10321 tgaaaagatg aagaataata ttggcttgaa atttgccttt cgttccactg acctagtgga
    10381 aatcaaaaag accttagaat tttttggtgt ggacaaggaa gatgaaaaca atcagaaacg
    10441 cttacgtgaa ttagaaaatg gacaatgttt agtttcagac atctatggtc gtgtaggggt
    10501 tatgcagttt cacccgattt ttgaagagtt gcttcatgcc tttgatacca gaccgcctgt
    10561 gcgaaatgag gtggaagaat gacacaaaaa caaaagaaat ttcttcacta tagttggata
    10621 acgctccttt gtgtgggcgt tattttactt ttattaggca cgctgggcaa tgcagtacaa
    10681 gcgacaggct tagttgatga aaccattgat acaagcaatg aatactccaa gtatggtttg
    10741 aatcaatatc agcttgatta ttatgtggac aatagctggg gctggcttcc atggaattgg
    10801 agtgatggca taggacaatc ggtgatgtat ggattgtatg ccattactaa ttttatttgg
    10861 acaatttctc tttatctatc gaacgccaca ggttatttgg tgaaagaagc ctatgcctta
    10921 gatttcatta gtcaaacatc ccaagcaatt ggcgaaaaca tgcagacgat tgcaggcatt
    10981 acaccgaatg gcttttccag ttcagggttt tatgtcggtt tcctccttct ttttattctc
    11041 attgttggaa tctatgttgc ctatacagga ttggttaagc gagaaacgac gaaagtgata
    11101 cgagctgttt taaactttgt cgtggtgttt attctatcgg cttcctttat tgcgtatgca
    11161 cccgattata ttgcgaaaat caatgatttt tccaaagatg tcagtaccgc cagtctgaat
    11221 attgggacaa aaattgttct tcctaacacg gatagtcaag ggaaagacag tgtggacatg
    11281 atacgtgaca gcttattctc tgttcaagta aagcaaccat ggctattgct tcaatatggc
    11341 tccactgatg tagaagcgtt aggggaagaa cgtgtggaaa gtttattgtc taccagtcca
    11401 gatacaaaca atggtgaaga tagagaaaat gtagtgattg aagaaattga agatcatgac
    11461 aatacctatt taaccctacc gaagacgatt tccagattag gaacagtctt ctttttgttt
    11521 gtattcaata ttggtatctc gatttttgtt ttccttctaa caggaatcat gattttttcg
    11581 caagtgctat ttattatttt cgctatgttt ttgccaatca gtttcctatt aagtatgttg
    11641 ccgagttttg atggcatggg caggcatgcc attaccaagt tatttaatgt gattatgaca
    11701 agggctggta ttaccttgat tattaccgtt gcctttagta tttccactat gctttattcg
    11761 ctgtcagcaa gttctccctt tttcatgatt atgtttttac aaattgtgac ctttgcaggg
    11821 atttatttta aactgggcga tttaatgagc ctattcactt tacaaagcaa cgactctcaa
    11881 aacatgggca gacaagtgtt tcgcagacct cgtcaaatga tgaatcgaca aaccagaaga
    11941 tttcaacgca gtatgagtaa gatttttcgt ggaaaagcag ggtcaacgaa gcaaaagaca
    12001 atgacaacaa agcagaatca aaccaataaa gctaaccata ctcgtcaaaa tgaacggact
    12061 acaccaaaga aagaaacagc actttccaat gtgaaaaagc aacaaggcgg tatcgggcaa
    12121 cgattaggtg aaaagacagc ccatgtattg gacacgaaaa atcgtctagt caataaaaga
    12181 aagcaggcaa aacaacagat acaggcgaca ccaacccatg tcaaatatgc ccttcatcaa
    12241 ggaaaagaga atgtcactca taatgtaaca gactttaaac aatctatggc agataccaaa
    12301 gctcaacgca aacaacagcg tatgaaccag caggagcaaa aacgaaagaa cattgctcaa
    12361 aagcgtttgg agctggataa agcaaaagaa aaaagacgaa aagaaaaccc atcatctcct
    12421 gttcagaata accagcagca tgttcgcaag cgtcagcaaa ccgtcacgcc tgttttgtca
    12481 caaaacacta aacgtgaaaa tcatcagcga ccattgaaaa aagagcaaaa acaaaagaca
    12541 ccaccgaagc aattcaatca gaggaagcta aataaaagaa cggataagcg aggacaacaa
    12601 acatgaagct aaaaataaca gtgatttgta gtgtggtctt ctctctcttc ttttttctct
    12661 tattattcct agtcattttc tttgcagatg atacggacag tggcgaaaac aacaaggatt
    12721 cttctattcc acaaggcggt gtgaccgttt caccagaagt gttggcacac cgtccgttga
    12781 ttgaaaaata tggtaaggaa tatgggattg aagactatgt ttcttatatc ttagccatta
    12841 tgcaagtgga atcgggcggt acagcagaag atgttatgca aagttccgaa tctttgggtt
    12901 taccgcccaa cagtttgagt accgaagagt ccatcaaaca aggggttaaa tatttcagtg
    12961 aattattaac cagtgcagaa caacaaggag tggatataga ttctgttatc caatcttata
    13021 attatggcgg tggcttttta aattatgtga ggagtcatgg gaaaaaatat acctatgaat
    13081 tagccgaaca gttttctaaa gagaagtcgg gtggtcaaaa agcagactat cccaatccta
    13141 tagccatacc tgtgaatggt ggttggcgat ataactatgg aaatcagttt tatgttcagt
    13201 tggtttcaca atacctaacc gacacttccc caacagaatt tgatgatgaa accgtgcaag
    13261 tcattatgga cgaagccttg aaatacgaag ggtttcccta tgtctttgga ggggcgtcgc
    13321 ctaccacctc ttttgattgt agtggcttaa tacaatgggt gtatgacaaa gctggcattt
    13381 ctctccctcg tgtcgcccaa gatcagtatg acgctacgca agaaatctct atggaagaag
    13441 cccaagcagg cgaccttatc ttctttcatt caacctataa tgcaggcaca tatgtgactc
    13501 atgtggcgat atatttagag ggaaatcgct tttatcatgc aggcgaccca atcggttatg
    13561 gcgacttaag cagtcgttat tggcaagacc atctgattgg ggctagacgt gttattcata
    13621 actaagaaag gaatgaatca aatgattata aaaatcgagc gaaaagaaaa gaaggagaaa
    13681 ccaaagaaat ctaaaaaacc gagcaagcaa agaaaagttc cgatgattaa agttggcacg
    13741 cataagaaat taacctttgt tttatgggtt ttattgattg gtagtgtcgg atttggaatc
    13801 tataaaaatt ttactgccat tgacactcat actgtccgtg aaacagaaat cattaaacag
    13861 cagattgtcg ataccaacca agtagaaagt tttgtgaaat cctttgcgaa agactacttt
    13921 tcgtggcaac aatcccaaga agccattgat aaacgaaatg aaaaattgac ccattatttg
    13981 acggaagaat tgcaggtatt aaatgaagaa atgattcgta aggatattcc tactagttct
    14041 agtgtgaacg atatacaggt gtggcaggtt tctcaagtga atgagaacac ctttgaggta
    14101 ctgttttctg ttgaacaagt tattaccgaa gacaaagaca aggaaactat atcgtctagc
    14161 tttcatgtgg ttgtccatat agatgaatca gataatatgg ttattatcaa aaatccgaca
    14221 atgagtaaga aacctcaaaa atcggactac caacccaaac agctagaaag tgaccataca
    14281 gtagatacag aaacgatgga cgaaatcact agctttttag aaacgttctt ccagctctat
    14341 cctaccgcca cagaaaaaga attgacttac tatgtaagta atcatgtgtt acctatgatt
    14401 aacaaggaat atgttttcga ggaattggtg aatcctatct ttaccagaaa agataaccaa
    14461 gtaatcgtga atgtcgctgt gaaatattta gatcaagaaa caaaggcaac ccaaatctcg
    14521 caatttgagt tgatattaga aaaacaagat aattggaaga ttgtaaaata acaaatattg
    14581 gtacatgatt acagatactt tgtaatcatg tactct
//
LOCUS       DADVXM010000063        13700 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.066, whole genome shotgun sequence.
ACCESSION   DADVXM010000063 DADVXM010000000
VERSION     DADVXM010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.066"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..901)
                     /locus_tag="KB927_002001"
     CDS             complement(<1..901)
                     /locus_tag="KB927_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBB6840911.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSE"
     regulatory      complement(925..969)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1184..2152
                     /locus_tag="KB927_002002"
     CDS             1184..2152
                     /locus_tag="KB927_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6840912.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2265..2543
                     /locus_tag="KB927_002003"
     CDS             2265..2543
                     /locus_tag="KB927_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBB6840913.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2661..2897
                     /gene="secG"
                     /locus_tag="KB927_002004"
     CDS             2661..2897
                     /gene="secG"
                     /locus_tag="KB927_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBB6840914.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3000..3755
                     /locus_tag="KB927_002005"
     CDS             3000..3755
                     /locus_tag="KB927_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6840915.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3758..6115
                     /gene="rnr"
                     /locus_tag="KB927_002006"
     CDS             3758..6115
                     /gene="rnr"
                     /locus_tag="KB927_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBB6840916.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKFGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6137..6601
                     /gene="smpB"
                     /locus_tag="KB927_002007"
     CDS             6137..6601
                     /gene="smpB"
                     /locus_tag="KB927_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBB6840917.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6903..7622
                     /gene="atpB"
                     /locus_tag="KB927_002008"
     CDS             6903..7622
                     /gene="atpB"
                     /locus_tag="KB927_002008"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBB6840918.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7675..7890
                     /gene="atpE"
                     /locus_tag="KB927_002009"
     CDS             7675..7890
                     /gene="atpE"
                     /locus_tag="KB927_002009"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBB6840919.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7981..8505
                     /gene="atpF"
                     /locus_tag="KB927_002010"
     CDS             7981..8505
                     /gene="atpF"
                     /locus_tag="KB927_002010"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBB6840920.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8492..9034
                     /locus_tag="KB927_002011"
     CDS             8492..9034
                     /locus_tag="KB927_002011"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBB6840921.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9057..10613
                     /locus_tag="KB927_002012"
     CDS             9057..10613
                     /locus_tag="KB927_002012"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBB6840922.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            10627..11529
                     /locus_tag="KB927_002013"
     CDS             10627..11529
                     /locus_tag="KB927_002013"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBB6840923.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11552..12958
                     /gene="atpD"
                     /locus_tag="KB927_002014"
     CDS             11552..12958
                     /gene="atpD"
                     /locus_tag="KB927_002014"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBB6840924.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12972..13394
                     /locus_tag="KB927_002015"
     CDS             12972..13394
                     /locus_tag="KB927_002015"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBB6840925.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4530 a         2450 c         2988 g         3732 t
ORIGIN      
        1 tttcggaaaa aagacgagta tctacttttg tcataatttt actgttagca ggtttctgcc
       61 aaaattcata acgatcaacc aatgtttgtc cacgacttat tccctgagtt tccacagcgg
      121 tgaagctttt gaaaccttca cagatggccc cctcgatgaa ataagcaaca gctaacggat
      181 cattgatgac acatcctaaa attctttctt gtttccagtg gaagtcaaaa taaaaacgag
      241 tgatcgcttt taaatactct ccctcttcag gattcatttg acagcagtat tcgaggatag
      301 tcggtgtcaa gacgatttct cttgtcacat ctaacccaac catttctatc gtttgtttga
      361 gattctcgaa tacataagaa gctgcttcag gatcacacca gtaattgtat tcagcaactg
      421 gcgaacagtt accatggctt ttgtaagttc cacccatcga gacaaaacga tccatatgtt
      481 tcccaatatt tgggttgact ttcaaagcaa aagcgatatt ggtcaaagga cccaaagcaa
      541 tgactgatgt atttgtcttt tctttgaaat aatcagccaa aaaatcaacg gcatggagag
      601 gttctgcctg ttttctcaag atcatcggga aatttgtttc ccctaaacca tccataccat
      661 gagtgtcttg tgcactgatg aaaggttgct tcaaaggttt ttccattcct tgataaacag
      721 gaatgtctaa acgatcacag cgttccaggc atttcagcac attctgcgta cctatatctg
      781 cagggacatt cccacaaact acggtaatag caactacttc gatatcaggg gatttgacag
      841 ctaatgataa agctaaagtg tcgtcgatcc ctggatcgca atcaataatt acttttcgca
      901 ttatttccaa tctcctttct ttagagatac ttagtttttt attctgggaa gtttccgaac
      961 cagtccaaga cgagcgtctt gattataatg cacgaaatta gtatactggc ttttattgcg
     1021 aatgtaaatg ctctcttaca agtaaatcta ttgaggagaa ctttaagtaa atgatacaat
     1081 gaaaaagaaa tggaatttac gtgtgccgaa aataaagaat cctatggatc ggtacattgg
     1141 ataatagata gattatagtt tggcagaaag cggcgggtgt acaatggtta ttttttattt
     1201 cattcttatt ctgataatta tagggatcag ttaccatttt ctttcttatt tttatgcaaa
     1261 gaaattagta agagcgggag tacagagagg atatgactgg tatgaagaca ctggtcatcg
     1321 tttgatggac cctgctgcag tcacgtcagt agaaaaaaaa cgacaaaaat tagaagaaga
     1381 gtgtgaaagc ttttgggagc agggaacacc caaaacaatc aaaagttatg acgggttgaa
     1441 actagctggt cagatgttca tccatccaaa taagcagaat aaatgggtca tttgcgtaca
     1501 tgattaccga agcacaggga aaagagacat gtctcatata ggtaaaagat atgcagagaa
     1561 aggattcaac gttcttgtac ctgatttacg tgcgcacgga gaaagtgaag gagaaatcat
     1621 cggaatggga tggctagatc ggctagattt aattgcctgg atccaactca tcttagatga
     1681 acagccgaat gcgtccatta ttttacacgg cggatcaatg ggagcttcta cgatcatgat
     1741 ggcaagtggt gaaaaacttc catcagcggt caaaggattt attttagaca gcggatatgt
     1801 ttctgtttat gcagaattcc gatatatgtt aagtaaaatc actgtctttc ctaaaaaaat
     1861 ggtcatgaga tatgcgaatc attatgccca gaaatacgcc ggttactcct taaagcaagc
     1921 atcagctacg agacagcttg gcagcaacca tctgccttta ttagtcatcc atggtgaaag
     1981 agatcatttt gtccctacag aagcagcgta cacgattcaa aatgctacgg caggggataa
     2041 agcactgctg cttgttccag aagcagaaca cttggaagca tcgatgaaag atccgaaaac
     2101 ctattggaca gtgatttttt catttattga acaaagaata acgatggatt aattttctct
     2161 tcttttttgt aagtaattcg aggataaata attgtttata gatctggaga ctgctaaaat
     2221 aaggtaggaa taaaaaaata tcagttattt gaggagtgcg gcatatggaa atcaaagaag
     2281 aaaaaaatcg tcttgcttta ttcaatgatg agcaacaaga gattggagaa atgacatggt
     2341 cagatgcggg cccagacatc atgatcattg accatacatt tgtagatcca gcatatcgtg
     2401 gtcaaaagtt agctgaaaag ctagtgtata ctggagtaga attagcaaga cgagacggga
     2461 aaaagatcat tcctttatgc ccttatgcaa aaaaagagtt tgaaaagaaa ccagaatatc
     2521 aagacgtctt acgtcagtca taagaataac agctgaaagt tttgaacttt cagctgttat
     2581 tccatttata tagagttgtc acggactttt atctatgata aagttaaaga gacgatatct
     2641 tttgggaagg aggctgcgat atgtataatt taattttggg aatcgtgatc gttttatcga
     2701 ttgttatggt cattgcgatt atgatgcagc caagcaagca aaatagtgca gcgagtgcat
     2761 ttaccggcgg tgcggatcaa ctattcggca aacaaaaagc tcgcggcttt gaagctgtca
     2821 tgcagcgatc aactgcagtt atgggagcta tctggatgat cttattattt gtcctagcat
     2881 atttatcttc gaagtagttg aataagcctc tcgcaaaacg gcgggcggct ttttttattg
     2941 caaagagaac gcttaagaag aagttatgaa agaaactatg gtaaaatgag gcgaaagagg
     3001 tgagacgagt gagacaatta ccaaaacccc tttatgcaaa acatggaaag cgagcggttt
     3061 tgctgcttca cgcttactca ggaagtccaa acgatgttcg aatgctcgca cgatttttgg
     3121 aaaaagcaga ttatacagtt tatgcgccgc tttttaaagg acacggaaca atggagccat
     3181 atgatatctt gcaagaaaaa gcagaaagct ggtgggcaga cactaaaaaa gccatccatt
     3241 ttttacagtc tgagcagttt tctgatattg ccgtattagg attatcaatg ggcggcatct
     3301 ttgctgtacg agcactagaa gaagaatcag tgattggcgg cggttttttc tgttcgcctt
     3361 tgtctcctgt aaaaacaaac gtgcctgaaa actttgaaaa atacgtacgt caagtgctga
     3421 agacagcagg taaatcagag aaagaaatca atgaaaaagc agttgcttac cgctcgttag
     3481 ctgaacaaca attaatggat atacaagatc aggcagcaat cgtagaaagt aggttgtcag
     3541 atatccaaca gccgatattt ttagctcaag ctgggaaaga tgaaatgatc gaccctaatg
     3601 gcgtatttga aactgcacgc aagttgagcc gtcagcgagt gacacttcaa tggtatcctg
     3661 aaagtggtca tgtgattaca gttggtacag caagacgcga attagaaaaa gacgtcttgg
     3721 aatttttaga aaaattacct tggaatgagg aataaatatg acaaaagaaa cgataaaaga
     3781 gaaaattctc tttttcatgg aaagcagtcg caaacgcagt ttttctatgg aagaaatcgc
     3841 tgaaggttta gggttccaaa aaagcgatga ttttaaatta ctagtacaaa cgattgctca
     3901 aatggaaaga gaacagagta tagttttcaa taaaaaagga aaagtgaaac ttcctttaaa
     3961 accaatcttg atcgaaggaa catttcgagc aaatgaacga ggatttggat ttgtaacgat
     4021 tgatcccgaa gaagatgaca tctatatccc aaaagaagcg actggttttg caatggatgg
     4081 agacaccgta gcaatcgata tcatgaagcg agcaaataca gatatggatc gcggagcaga
     4141 ggggaaagta gtcgagattc gagaccgggc gactactcag ttagcagggg aattcgttgc
     4201 ttattcagaa gaagaaatac aagaaacaga tctttacggc gttgttatcc cgaaagatag
     4261 aaagctcaac caatttaaag tatatgcagc agcagaggga gttcgtccag ttgacggaag
     4321 tattgtgctg atcgaactga cccattaccc tgaaaaaggg tatgcgacta gtttagaagg
     4381 gataatcaag caagtgattg gtcataagaa tgaccctggc atggatatcc tctcaattgt
     4441 cgtggctaat ggtatcccta cgaaatttcc tgatgatgta ttgtctgaag cagatgaagt
     4501 tccagatcaa atcagcgaaa aggatataac tggacgtaga gatttaagaa atcagctcat
     4561 tgttacgatt gatggagaag atgcaaaaga tctagatgat gcagttacgg ttaaaaaatt
     4621 agataacggt aattattttc ttggagtaca cattgcagat gtttcttact atgtgacaca
     4681 aggcagtcaa ttggacagag aagcatatga aagagggaca agtgtatatt tgactgatcg
     4741 agtgattccg atgatcccgc aacgtttatc gaatggtatc tgttcactga atccccatgt
     4801 tccaaggctg accatgagtt gcgaaatgga gattgatcca aatggacaag tagtctctca
     4861 tgatattttc ccaagtgtga tccaaacaac agaacggatg acctacacag ctgtcaatca
     4921 aatcttagaa gatcaagacg aagaaacgat gcaacgctat gctcagctcg tacctatgtt
     4981 ccaagaaatg ggtgaattgc atcgaatcct tgaaacgatg cgaatcaaac gtggcgcgat
     5041 ttcttttgag gatcgcgaag cgaaaatcct tgttgatgct gaaggacacc caaatgacat
     5101 ccagctaaga agcagaggaa ttggtgaacg cttgatcgaa tctttcatgc ttgcggccaa
     5161 tgaaacggta gctgaacatt ataataaatt aaatctgccg tttatttacc gaatccatga
     5221 acagccaaaa gaagaaaaaa tgcagcgctt ctttgatttt gcttcagctt tgggcattct
     5281 ggtccgagga acgaaaggaa cgatcacacc aaaagattta cagcatgtga tcgaaggagt
     5341 agaagacaaa ccagaagctg cagttatcaa tactatgttg ctaagaagca tgcaacaagc
     5401 acgctattca gaagacaatt ttgggcatta tggcttagcg gcagattact acacacactt
     5461 tacatctcct attcgacgct atcccgatct aatcgtccat cgtctgatcc gttcttacag
     5521 tgaagataaa agtgaaagca atcaaagttc gtgggctgcg gaacttcctg aaattgcaga
     5581 tcatagttct aagatggaac gtcgtgcagt agaaacagaa cgtgaagtag attccatgaa
     5641 gaaagcagaa ttcatgatgg acaaagtggg agaagaattc gatgggatca tcagctctgt
     5701 tgtgaaattc ggcctgttta tcgaactgcc gaatacagta gaaggattga tccatatcaa
     5761 tgaattgaaa caggactact tccattttgt tgaaaatcat ttagctcttg taggtgaaag
     5821 aactggtctg acttttaaaa tcggacaaaa agtgcgcgta aaagtagtca aagctgatcc
     5881 agatgaacga gcagtggatt ttgaactcgt ttccgcagaa gaggtcactg cgttggaacg
     5941 tccaaaagca cgcaatggaa aatttggaaa acgagaagga aaacaagcag gcaaacgctc
     6001 agaaaaaaat ggcaagaaga acaaacgata tagtgatagt aagcaaacgt tcggtaagaa
     6061 aaaagggaaa aagccatttt acaaagatgt caaaaagaag aaaaagaaaa aataaaatga
     6121 gttggaggaa acagctatgc caaaaggcga gggaaaacta attgcacaaa acaagaaagc
     6181 tcgccatgat tattcgatca tcgacacgat ggaagcaggg atggtcttgc aaggaacgga
     6241 gatcaagtcg atacgaaaca gccggatcaa tctgaaagat ggatttattc gcgtccgcaa
     6301 cggggaagct ttcttgcata atgttcatat cagtccttat gaacaaggaa atatttttaa
     6361 tcatgatccg ttgcgcacga gaaagttatt attacacaag aaacaaatcg ttcgtcttga
     6421 aaacgaattg aaaaacactg gaatcactgt tgttccttta aaagtctata ttcgtaacgg
     6481 ctatgccaag gtattgattg gtctggcaaa agggaaaaaa tcgtatgata aacgggaaga
     6541 tttgaaacga aaagatatcg atcgacaaat tgatcgaaca ttaaaaaatt tctctagata
     6601 atttcattat cctttttcgc atattcggtg cttttgcttt tacttaatga taaaatttgt
     6661 tagcatttaa tctgataaaa catgattatc acaggttttt tcttagatca ggagcaccgt
     6721 gcatggggaa aaattcgctt cgtttttgac tgaaataaaa aagtgtctaa ttttcatgaa
     6781 aatgttttga attttctgtt tcatggtggt atgataccgt gtggttagaa accgattgga
     6841 aaaaaccaga tacgcacatg aattgatttt atgtgaattt cggggaaaag aggtgaaatg
     6901 gattggatga acgctcgcta acgtttcaca ttggaccaat ttggtttgat ggtacagttt
     6961 gtataatggt gttactgacc tgtttgattg ttttcttctt agcttacttt tttacaagaa
     7021 atcttaagtt gaaaccaaca ggcaaacaaa atgcgataga atgggtcatt gattttagtc
     7081 gaggaatcgt aacagataat ctgcctagaa aagaattgag caatttccat ttgttggcat
     7141 ttacattgtt tttatttgtt tttgttgcaa acaacatagg tttagtaaca aaaatcgtct
     7201 tacctaacga aacaacactt tggaaaagcc cgacagcaga cccgtttgtt actttaactt
     7261 tggcatttat aatgatctta cttactcact tattcggggt gaaaaagtta ggcttcaaag
     7321 gatatttcgt aaattcgttc ttgaaaccct atagttttat gtttccgatg aaactgattg
     7381 aagaatttac aaatttatta acacttgctt tacgtcttta tgggaatatt tatgcggggg
     7441 aagttttgct aaccttgatt gcaaaaatga tgacaagctt aggctggttc tcattaccat
     7501 tagcaattcc attagagatg gtctggatcg cgttctcctt gtttattggg agcatccaag
     7561 catttgtctt tgtcactttg tcaatggttt atatgagcca taagattgaa gtagaagaat
     7621 aatactcggt taaaaaacaa actactattt atctatttta ggaggaaaac aattatgaat
     7681 tatatcgcag cagcaatcgc aatcatggga gcagcaatcg gagccggtta tggtaacggt
     7741 caagttatct ctaaaacaat cgaatcaatg gctcgccaac ctgaaatgtc tggtcaattc
     7801 cgtacaacaa tgtttatcgg ggtagctcta gttgaagctg ttcctatctt aggggtagtt
     7861 atcgccttga ttctagtttt tgccgtttaa ttgaatcagt attaaggcag aaacaacatc
     7921 gtttgttact gcttttttac atggaaacta gaaatactcc aaagaaagga aggctcgcct
     7981 atgctgaatc aattggcaat tgcagaagtt ggcaatgcga tgttaggtaa tatcatcgtt
     8041 gtcagcggct catttttgat actactggct ctcttgaagc actttgcttg gggaccaatc
     8101 agcgatattt tgaaaaaacg tgaagacaag atcgccaatg atttagattc tgcagaacaa
     8161 tctcgcatca actcagcgaa aatggaacaa gaacgcgaac aacaattgtt agcctctcgt
     8221 tctgatgcag ctgatatcat caaaaatgcg aaagaaagtg gagaattaag ccgccaaaat
     8281 attttgaagg atgctcaaga agaagcagct cgtctaaaaa gcaaagccca agctgatatc
     8341 actgtagaac gtgattcagc gctgaactct gtaaaagacg acgttgcaga actctctctt
     8401 caaatcgcgg aaaaaatctt gaacaaagaa ttatctccag aaatgcatga atcattaatc
     8461 aatcaataca ttgaaggtct aggttcttca aatgaaacta gataaatata cagtaggaag
     8521 acgttacggg aaagctttat ttgaactggc gatcgattca aatcaagcag aagaaatcta
     8581 tcaagatctc gtaagtttac gtcaaatcta tgaacaagta cctggattag ggaatatgtt
     8641 aagtgatgtt cgtctagaac ctcatgaaaa acgagaaatc atggacaagc ttgtcagcgg
     8701 ttatgatggg atcgttaaaa actttttaga agttgtttat gagtataacc gaatggatga
     8761 ccttttgttc atgatcgaag aatatgaacg tcgatatgat gaacatcaag ggttactatt
     8821 gggaagtgtc acaacagcag tcccactttc agacgaacaa cgaatacaat tagaaaagaa
     8881 tgttgcaaaa acaatggact atcaatcagt tgaattaaaa caaatcgttg attcttctat
     8941 tattggtggc gcgattgttg aagccaacca tcgagtaatc gacggaagca ttcgcacgca
     9001 attagaaaaa atgcgtaatc aattaaacag atagtacaaa gaggtaggtg aatcgaatgg
     9061 ccatcaaagc agaagaaatt agtgccttga ttaaagaaca aattgaaaat tatcaaaacg
     9121 tgctttcagt cgaagaaatc ggtaccgtaa cttatgtagg tgacgggatc gctcgtgcac
     9181 atggtttaga aaacgcgatg agtggtgagt tgcttgaatt ttcaaacggc tcatacggaa
     9241 tggcgcaaaa cttagagtca aatgatgtag gtatcattat ccttggcgat ttcgagtcca
     9301 ttcgtgaagg agataaagta aaacgaacag gtaagatcat ggaagttcca gttggagagg
     9361 ccttgatcgg tcgggtagtc aatccgctag gtcaaccaat cgacggacta ggtgaaatcg
     9421 ttactgacaa agctcgtcca gtagaagcga tggcaccagg tgttatgcaa cgtaaatctg
     9481 ttaacgaacc aatgcaaaca gggctaaaag cgatcgacgc ccttgtgcca atcggacgcg
     9541 gacaacgtga attagtcatc ggtgaccgta aaacagggaa aacttctatt gcgatcgata
     9601 cgatcatcaa ccaaaaaggt caagatatga tctgtatcta tgtagcaatc ggacaaaaag
     9661 attctacagt tcgtacacaa gttgaaacat tgaaaaaata tggcgcaatg gattacacaa
     9721 tcgttgtgaa tgccggtgcg tctcaaccag caccattgct ttatatcgca ccatatgctg
     9781 gtactgcaat gggtgaagaa ttcatgtaca acggtaaaca tgtattgatc atttttgatg
     9841 atctttcaaa acaagctgtt gcttatcgtg aactttcctt gctgcttcgc cgtccaccag
     9901 gtcgtgaagc ttatccaggg gatgttttct acttacactc acgcttattg gaacgtgcag
     9961 caaaattaag tgatgattta ggtggcggtt caatgactgc cttaccattt gttgaaacac
    10021 aagctggaga tatctctgct tatatcccaa caaacgttat ttcgatcact gatggacaaa
    10081 tcttcttaga aagcgacttg ttctacgcag gtactcgtcc agcggttgat gccggactat
    10141 ctgtatctcg tgtagggggt tctgcgcaaa tcaaagcaat gaaaaaagtt gctgggactt
    10201 tacgtctaga cttagcaagt taccgtgaat tagaagcatt tacacaattc ggttctgact
    10261 tggatgcagc aacacaagca aaactaaatc gtggacgccg tacagtagaa atcttgaaac
    10321 aaaaattgca tgcaccgcta gctgttgaaa aacaagtagt gattttgtat gctttgacac
    10381 atggattctt agatagtatc cctgtagaca gtattttaga cttcgaacat gaattattcg
    10441 aatatctgga taccaatcat tcagatatct ttgaaacaat ccgtacaaca aaagatcttc
    10501 cagaagaaga agcgttgaac agtgcgattc aggaatataa agacatgttc ttagctacaa
    10561 aaggaaataa ttcctctaca gaagataaat tgaaatccat tcaaaatgca tagtgaggtg
    10621 agatgaatgg gtgcttcatt aaatgaaatc aagacacgta tcgcttcaac gaaaaaaacg
    10681 agccaaatca cgcgggcaat gcagatggtg tctgcttcta agttgacaaa atctgaagct
    10741 tcttcacaga agtttcaggt ttatgcaaca aaagtaagag aaatcgttac gcatttgact
    10801 gctactcagt taaatgatat tgcctcagaa aatcctagag gggatatcaa ttacaacagc
    10861 atgttgctca gccgtcctgt taagaaaacg ggttatatcg tcatcactgc agatggcggt
    10921 ttagtcggtg gatataacag ctcgatattg aaacaaacga tgtctatttt agaagaagac
    10981 caccaatcac ccgatgatta cgtgatgatc gcaattggcg gaactggtgc agacttcttt
    11041 aaagcacgcg gtatcaatct agcatatgag ctgcgcaatc tatctgatca gccaagcttt
    11101 gatgaagtcc gcaaaatcgt aaatatggca acaactatgt accaaaacga agtattcgat
    11161 gaattatacg tatgttataa ccatcatatc aattcgctaa ctagtcagtt tcgtgtagaa
    11221 aaaatgctgc caatctcaga cttagatcca gaagaagcaa ctactttcga acaagaatat
    11281 atttttgaac cttcaaaaga agaaatcttg tctcagttat tgcctcagta tgctgaaagt
    11341 ttgatctacg gtgcgatcgt tgacgccaaa acagcagaac atgctgctgg tatgacagca
    11401 atgaaaacag caactgataa tgctgctaat atcattgatg agctgacggt ttcttacaac
    11461 cgtgcaagac aaggggctat tacccaagaa attaccgaaa ttgttgccgg agcttcggca
    11521 ctagaatagt attgagattg gaggaaaaaa gatgagttca ggcaagattg ttcaagtaat
    11581 cggtcccgtt gtcgacgtgg aattttcttt agaccaatcc ttaccagata tcaacaacgc
    11641 attagttgtt tataaaaatg acgaaaataa atcaaaagtt gttcttgaag cagcgttaga
    11701 attaggggac ggagtgatcc ggaccattgc gatggaatca acagatggtt tacaaagagg
    11761 aatggaagtc attgatacag gcaaagcaat ctctgttcct gtaggtaaag aaacattagg
    11821 tcgcgtattc aacgtactag gagatacgat cgatttagaa acacctttcc cagaagatgc
    11881 ggaaagaagc gaaattcata aaaaagcacc agcctttgac gaattaagta caagtacaga
    11941 aattttggaa acagggatca aagttatcga tttgcttgcc ccatatttaa aaggtgggaa
    12001 agtcggacta ttcggtggtg ccggtgttgg taaaaccgta ctgatccaag aactgatcca
    12061 taatatcgcc caagaacatg gtggtatttc tgtatttacc ggtgtaggtg aacgtactcg
    12121 tgaaggtaat gacttgtatt atgaaatgaa agattcagga gttatcgaaa aaacagccat
    12181 ggtgttcgga caaatgaacg aaccaccagg tgcacgtatg cgtgttgctt tgactggttt
    12241 gacgattgcg gaatatttcc gtgatgtaga aggtcaagat gtactgttgt ttatcgacaa
    12301 cattttccgt ttcactcaag ctggatctga agtatcagcc ttgttaggac ggatgccttc
    12361 tgcggttggt tatcaaccaa cattggcaac agaaatgggt caattgcaag aacgtatcac
    12421 atctacgaaa aaaggttcga tcacatcgat ccaagcaatc tatgtgccag ccgatgacta
    12481 cactgacccg gcgccggcaa cagcattcgc ccatttggat gcgacaacca acttggaacg
    12541 taaattaaca gaacaaggga tttatccagc ggtagatcca ttggcttctt cttcaagtgc
    12601 tttagcacct gaaatcgtgg gagaagaaca ttataaagta gcaacagaag tccaacacgt
    12661 attgcaacga tatcgtgaat tacaagatat cattgctatc ttaggtatgg atgaattatc
    12721 cgatcaagaa aaagtgttag tttctcgtgc ccgcagagtc caattcttct tgtcacaaaa
    12781 ctttaacgtg gctgaacaat ttactggtct tccaggttca tatgtccctg tagaagaaac
    12841 agtgaaagga ttccgcgaaa tcttggaagg caaatacgat gatcttcctg aagaagcttt
    12901 ccgaagtgtt ggccgaatcg aagacgtcgt agaaaaagcg aaaacactag gctactagaa
    12961 aggggtgccc catggatcaa tatttaacag taaatgtggt aactcctgcc ggtttggtct
    13021 atgatcacca tgcagctatc gtcgttgcac gtacgacagc tggtgagctt gggattttgc
    13081 ctaaacatgc accaatcatc gttccattga cgattgatga agttcgtgta aaacgaacag
    13141 attcagatac ccacgtcgat tggatcgctg ttaatggcgg aatcatggaa gttcgtgata
    13201 atgttgtttc aatcgttgct gatagtgcgg aacgtgaacg tgatatcgat gtatctcgtg
    13261 cggaacgtgc aaaacaacgc gcagaacgcc aaatcgaaga agcaaaagca aaacaagata
    13321 cgaacgaatt gaaacgggca actgttgcgt tgcaccgagc aatcaatcgt atcaaagtat
    13381 ctaagcactc ataaaatgag atgcggatgt ttatccgtgt ttaagaacag taaaaagagg
    13441 ttatgacaga agtggtcagc ttcaagacat aagaaggaat ttacgaaaat tgcttctcaa
    13501 atttttgtga aatctcagct tatttttcga agaagctact tctggaacac cgtatatcgg
    13561 aggttgtgaa atcagcgttt tgtcctgagt attagagaaa caaatggaaa atagttcctc
    13621 atattttgcc gttttttgag ctaataccga gggtcagatg attgaacacc gtttatttgg
    13681 aataagggac tgcgacaaga
//
LOCUS       DADVXM010000064        13258 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.067, whole genome shotgun sequence.
ACCESSION   DADVXM010000064 DADVXM010000000
VERSION     DADVXM010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.067"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            402..974
                     /locus_tag="KB927_002016"
     CDS             402..974
                     /locus_tag="KB927_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBB6840926.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            1119..1823
                     /locus_tag="KB927_002017"
     CDS             1119..1823
                     /locus_tag="KB927_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6840927.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            2051..2389
                     /locus_tag="KB927_002018"
     CDS             2051..2389
                     /locus_tag="KB927_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840928.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2374..3228
                     /locus_tag="KB927_002019"
     CDS             2374..3228
                     /locus_tag="KB927_002019"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBB6840929.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3375..3608
                     /locus_tag="KB927_002020"
     CDS             3375..3608
                     /locus_tag="KB927_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBB6840930.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3806..5710
                     /locus_tag="KB927_002021"
     CDS             3806..5710
                     /locus_tag="KB927_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBB6840931.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISVGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            6020..6382
                     /locus_tag="KB927_002022"
     CDS             6020..6382
                     /locus_tag="KB927_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6840932.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            6399..7010
                     /locus_tag="KB927_002023"
     CDS             6399..7010
                     /locus_tag="KB927_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HBB6840933.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(7112..8020)
                     /locus_tag="KB927_002024"
     CDS             complement(7112..8020)
                     /locus_tag="KB927_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6840934.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(8062..8376)
                     /locus_tag="KB927_002025"
     CDS             complement(8062..8376)
                     /locus_tag="KB927_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBB6840935.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            8675..10606
                     /locus_tag="KB927_002026"
     CDS             8675..10606
                     /locus_tag="KB927_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBB6840936.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTAMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            10899..11450
                     /locus_tag="KB927_002027"
     CDS             10899..11450
                     /locus_tag="KB927_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6840937.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            11763..12305
                     /locus_tag="KB927_002028"
     CDS             11763..12305
                     /locus_tag="KB927_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840938.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
     gene            12816..13258
                     /locus_tag="KB927_002029"
                     /pseudo
     CDS             12816..13258
                     /locus_tag="KB927_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4341 a         2214 c         2749 g         3954 t
ORIGIN      
        1 ttctagataa atggcataaa ttttcagcgc taagtgacaa aagcaactaa tttttcatga
       61 gagattttta aatatctcaa tctatctcca aaattagttg tttttgtagc tatagttgac
      121 tatgaatatg acaaataatt agaaaaaact gtgccaatta agtataaaaa tgacatttta
      181 ggccctactt taatgaaatt tttgtttgga gggaacgact tcattccttt gattatttca
      241 gttgaattta atagagaagc ctggcgtcta ttaagaaata attttcttga tgagcgtcaa
      301 tttttttaac ggaaatctat cctatactaa attcagtaaa gaaaaaggag gaatcaaaga
      361 aagctatttt aaacaaacca aaattatagg aggaataaat catgactgaa aataaagcta
      421 ctcaagaaag aacaccccaa gaaagattgc aagaagaaca agaacacaag gaacatgttc
      481 atcatacgaa aattaatgca gcggccattg cggatcatct tttaggcaac atgcatacat
      541 tacatgtgaa actgcaccaa tatcactggt atgtaaaagg agccaatttc tttacgttgc
      601 atgaaaaatt tgaagagttg tataacgaaa atgaaaaatg gttcgacaaa cttgcggagc
      661 gtctaattac ttctgggcat aaacctgctt cgacaacggt tgaatttgaa aaatattcga
      721 tgctttcgga agatgcagtt aataaatacg ctaaagcaga agacatggtt gaaaatatta
      781 tcgaggactt cagaagcact cgtgacctaa ctattcgcgc gattcgttta gctcaagacg
      841 agggtgacga tgctttagaa gatacattga ttgcttttaa aaatgactta gacaagaaca
      901 tttggatgct gcaagcgttc attggtaaag aagcattaga agatgatgac gctcttgatg
      961 aggatgaaga ttaaggtaaa agtagaagct gatttaggga ttggaattct ttccagtcct
     1021 ttttccattt tcttgatgtg catcaatttt tttgtagtaa gagacttata taataaaagc
     1081 agcgaatata aacaaaataa ataaaggggg agaatgaatt gactaaacat acccatcatg
     1141 aaattggcga ccacgcagcc tgtatccgct tggttccaat attcaatcac ttagaggata
     1201 gcgcgatgaa ttacattgct gaaaaagccc acacgaaaca gtatcaaaaa ggagagtttc
     1261 tgtttcgttc acaagaaaaa gaggatactt tatatattat caatcgtggg aaaatccgta
     1321 tttatcgatt ggcagactct ggcaaagagc agctagtgcg gatcttgaac cctggtgatt
     1381 tcaccggaga atggaccttg ttcaacccgg atgcagtaca cgaggaatat gccgaagcaa
     1441 cccgagatac cgttgtctgt atgattcagc aaaaagatgt ccaagatttt ctggaacaat
     1501 acccagctat ttctttaaaa ctattggcgg aaatgtctaa acggttagaa agttcagaac
     1561 gtcaaacgac acaagtagcc gtggagagtg tcattacccg tttagttttg tttttggcag
     1621 aaaatgtgga acctgaaatg ggcaactctc ccaccatcac cctgccgatg gcaaaaaagg
     1681 acattgcttc ctatttagga acgacacctg agaccatcag tcgcaaattt ggagaattgg
     1741 aggacgaagg attgattcaa cagctgtctg ggaaaaggat caagattcag gatttagatg
     1801 atttattgct ttacagcgaa taatcggaca cacttttttc tacacgttgg tgttctgtcg
     1861 ctcttcatta acaacgggac agaactcagt gcttttgctt ccatctgtcc gtttttggct
     1921 tttttaagac agaacgacct tcattcattg gaaaaataaa agcacaaaca tgataaccct
     1981 caagtttttt tgttttattt ttctttaaga tagggttgtc gaacaaaacg taaaaataag
     2041 tagggtgaat gtgcattgtt tttgggtgat agttgccatc acgttgtcag cagcgggggc
     2101 attctttgtc gtccctttca ccaagaacac gattggcggc gaagcaaaaa cgtctaacgt
     2161 tgttgaggca gataggttag ctatggaaaa agaagaggaa gttgtaaaag gagccggcgt
     2221 aatcggacac ggaaaagtgg cgtattacga agcgagtgac cagggagata aaagtgtatt
     2281 cactgtttgg tttccatgga gcttagccgg aatcttgttc agcatcacca tgactagaat
     2341 gacgcgaaaa attgaagaaa tggagcaaat agaatgggat tcgtattagg cgttttgaat
     2401 ccccatgtgg tggagattgg ttctgttgtg attcattggt atggagtcat tattgcagcg
     2461 ggcatattag cggctctcca gttgagcacc aaggaagcaa agaaaaaagg actggaagag
     2521 gataccatta tcgatatggc cttatgggca attccgattg gactcctcgg cgctcggctt
     2581 tattatgtgt tatttgaact tggttattat ctgcaaaatc caggacaaat ccttgcgatt
     2641 tggaatggcg gcattgcgat ttatggggga ttgattgcag gagggggtac gctatattgg
     2701 tatgcaaaga aaaaaggtac ttctttggca ctcgttcttg atattttagc gcccaatgta
     2761 ttgttagccc agtccattgg tcgttggggc aattttatga atcaggaagc tcatggtggg
     2821 ccggttactc gtcaattctt ggaaaatctt tatttacctg aatttatcat tgaacaaatg
     2881 aatatgaatg gtacctacta ccatccgact tttttatacg agtcattgtg gagtttgttg
     2941 ggctttgtcc tcatcgtcac tatacggaac cgaaaacagc ttttgcgtca aggagaagtc
     3001 gctttgagtt acgttttgtg gtactcagtg ggtcggttct tcattgaagg tatgcgaacg
     3061 gacagtttat ggattggcga gtggatccgc gtttcgcaag ccttgtctct ggccctgttt
     3121 attggcgcga ttgtagtatg gtttatacgc agacaagatt atccaccaat ttcttattat
     3181 tctgatggca ataaggggca gaaaaagact attaagatgg tgaattgagc aaaaagataa
     3241 aaagaagtgc aaaacttgat atgcgtcaat tttcgtttgc taaaagtgag ctatactaca
     3301 gttgtaaaga ggaaaaggca gtgttcatta atctgctgcc gataaaataa aaacacataa
     3361 aggagatagg aattatggaa aaagctatat tgcaattaga aacgttgtct tgtccaagtt
     3421 gtatgcaaaa aattgaaggt gccgtgaaat cagttaacgg tattgataaa gacagcatta
     3481 aagtattatt caactccagc aaagtcaaaa ccaattttga ttcagctgtc acttcgattg
     3541 aagagattca aaaagctatc gaaaacgtag gctatccggt tcttaaagca aaagtcaagg
     3601 ccgtttaaca gattaaatga actaggcaat tctggaagaa aagctatttt tccaggattg
     3661 ctttttttgt tgcaatccga ttcgaggtgc ttagaaacga taaaagagaa ctttctaaac
     3721 ttgatgtcag tcaattaatt acttaggcaa ttatcttata ctgtgtttat caataaaaga
     3781 gaaattaaat ttggagggaa aaagcatgca acaatatata ttaagcaaga aaaatgttat
     3841 caccgtcatc agtggattgt taatcgtact cggtttcttc agtcactttg ttttagaaaa
     3901 cgtaggactt tcagagtggt ctttgatcat cgcctctgtc tttgggatta cgccaattgc
     3961 cattcaagcg tttcaagcaa tgaaagtcaa agtcatcagt attgatgtct tagtcagtat
     4021 tgcagcgatt ggtgcgcttt ttattcaaaa ttatgaagaa tcggctattg tcacgttctt
     4081 attcttattc ggacactact tggaacaacg aacattgaac caaacgcgat ctgctatcaa
     4141 agaattgact gaaatggcac ccgaaagcgc cttgaaacaa atggataatg gcgaatttga
     4201 agaagtagaa gtggatgata tagatgaagg ggatatcttg ctcgttaaaa cgggtgcgaa
     4261 agttccagta gatggcatag tccttacggg tgaagggcat atcaatgaag ctagcattac
     4321 aggtgaagct attccggtca acaagctagc tgatgcagaa gtttttgcag gaaccatttt
     4381 agaaaacgga acgattcaaa tcagagctga ccgagttggt gaggacacca catttggaaa
     4441 aattattgaa ctcgtggaag aagcacaaga ttctaaatcc gaagcggaac ggttcattga
     4501 tcgcttttct aaatactaca caccagctgt cttggttctg gcaattgttg tatgggcgtt
     4561 cagtcaaaat attgagttag caatcaccat cttggttcta ggttgcccag gcgcattagt
     4621 tatcggagtg cctgtctcaa acgttgccgg tattgggaat ggtgctcgta acggtgttct
     4681 tttaaaaggg agtgaagtca ttcaagactt cagtaatgtg gatacaattg tatttgataa
     4741 gacaggtact ttaactgtcg gaaacccaac cgttgcagcg actgaactgt atgaaaaaga
     4801 tcctgctgaa acgcttggct atctggccag tgtggaacgg gaatcagatc atccattagc
     4861 aaaagcggtc ttaaatcaaa ttggagaaac aaacttttat cctgttgaag gaactgaagt
     4921 tgtgaaaggc ggcggaatcg tttcaagtgt agctggacat agagtggctg ttgggaatgt
     4981 ggccttgatg gaaaaagaaa atgtcactct cagcaaaaaa gtgcaaaaag atgtcaaacg
     5041 gtttgaacaa caagggaact ctctcgtttt gacagcggtc gacggtgaat taaaagtact
     5101 gatgggcatt cgcgatcaag tccgtccggg tgtgaaagct aatttgcagg aattaaaaga
     5161 cttgggcgtg aaaaatctag tcgttctttc aggagataac caaggaaccg ttgatgtggt
     5221 cgccggcgaa cttggtttga ccgaagctca cggctacatg ttgccggaag acaaatcggc
     5281 ttatatcgga aaacttcaac aacgtggtca aattgtagcc tttgttggag atggcgttaa
     5341 cgatagtccg tccttagctt tagcagacat tggaatcgca atgggaagcg gaacggacgt
     5401 agcgattgaa acatccgatg tcgttttaat gaactcgaac ttcagcaact tgcctcacgc
     5461 attaggatta gtaaaagcca ccgcaaataa tatgaaacaa aatatcgtga tttcagttgg
     5521 agtagtgttg gtcttgttga ccagcgtctt cttcagcgaa tggatgaata tgtctatcgg
     5581 aatgttggtt catgaaggta gtatcttggt ggtaattttc aatggcatga gattaatgaa
     5641 gtataagttg aaaggtcgaa aagaacaaaa agaagtatca gcacctgcag agaaagtaaa
     5701 aatatcttaa gaataaatta gaagaggctg agacaatagt ccatccttga aatgacaaaa
     5761 gcggaaactc agatttttaa atctgggatt ttccgctttt ttgagttctt gaaaaaaaat
     5821 aagagtatag agtatgttct ttataaaatt aattttcgtg taaatgatta aaaaatttaa
     5881 taataaaatt taaattccta ttaagttgta acacatgaaa ttgcttataa tagtgtattg
     5941 aaattaaggt agattgacaa acgagtgatc aaatagatat actaccttca aacgaccgtt
     6001 tgaatgtgag gtgagatgaa tggaaaaagt ttgccaagtg actatcgtac ataaagaaaa
     6061 agtaaatgta ataaaaaaaa aattggatca aaaagatttt tcaaacttac ttgtgttagg
     6121 gaaatgtttc agcgattctt ctaggattaa aattttctat gctttagaaa cctataagga
     6181 aatgtgtgtc tgtgatttag cagaaatact tactgctagt gtcgctacaa cgtcacacca
     6241 tttacgtttt ttaaaaaaac atggaatggc aaaatcacgt caagatggaa aagtagttta
     6301 ttattcttta gcgaatgaag acatcctttc cgctattcgt gtttttttaa agttatcaga
     6361 aaatctatct atgaaatctt agtttggagg aagttatttt gttacaaagt attttttcag
     6421 ctatcgctgt ttatatttct accagtattg attatttgtt tatcttgctg attatctttt
     6481 ctcaaagcca cacaaaaaaa ggtattcgtc acattttttg gggtcaatat cttggaacag
     6541 gtattttggt agccgtaagt ttgtttgctg cttatgtgct aaattttatt ccgcaagatt
     6601 ggatcattgg tcttctcggt ctaattccga ttttcttagg aatcagagtc gcttttgttg
     6661 gcgaagagga ggaagaagaa gaggaagtcg ttgaaaaact cgaatctaga ggaactaatc
     6721 gcttattctg gacagttgcc ttaataacga ttgcttctgg aggcgataat ttaggtattt
     6781 atattccata ctttacctcg ttagcttttt cagaaatcat tattgcttta atcgtattcg
     6841 ctatctctgt tgcggttctc tgctatatca gttacaaatt agccaagatt tcttttgttt
     6901 ccgaaacgtt agaaaaatac gaacgaatca ttgtccctat aatgtttatt gcgttaggaa
     6961 tttttattat gatagagaac gggacgatac aaacgctact aggtttttaa aaatcataat
     7021 cacgaaagat aaaaagagag gcagcgacta atcaaaatcg ctgccttttt tgcttttcaa
     7081 ataatgaagt attttttagc gtagaactat cttacgtgtt gtgggagtat cccttttcaa
     7141 gctcttcttt gcttgtagtt atttctattg tgatatgatt ctctacgctt gatttgtgtg
     7201 cgacttctgc aatttcttct tttatttccc tagccttgtc tatgtctgaa gggtctataa
     7261 gaaccgtgat gataagggcg ttttcttccc cgtccagtga ccaaatgtga aaatgtgaga
     7321 ggtcttttac agcaggaaca tttttaatgg agtccgccaa gctctttacg tttacatttt
     7381 caggcgaacc attcaataaa attttcattg tggtgaaaaa ttcaggaacg gttttgtaga
     7441 ggatataaag tgcaatcaaa atcgataaga taggatccag acgatatgcc tcggtaaagt
     7501 tcattagaat actcacaatc aagactccaa tccaccctaa tacgtcttcc agcatatgga
     7561 ggttcaacat gctctcgttt ttggatgtgc ctttgcttaa aatccacgca gcatatccat
     7621 tcaatgcaat agctacgaga gaaagccaga acatgccact ataatttacg ggttgtgggt
     7681 caatcaaacg tggcacacta cgatagatca taaaaaacga gccactaatt agcacaacgc
     7741 cagttatcag cgcgcccagt aaagaaaagc ggttatagcc aaaagtgaac cgttcatctt
     7801 gttttttctc tgaataacct tgaaaaaacc aagcgaatcc aattgaaata gagtccccta
     7861 aatcatgaac tgcgtcggac ataatggaca cactattgaa aagaaagcca aagaaaaatt
     7921 cgcttataga gaaaataaga tttatgaaga aagcaatttt aatattcttt ttcggttgat
     7981 tctgattcga gtgattatgg tctttatctg attttgacat ttaaaaacct cctaagtttg
     8041 tatgctacat actaattggt tttatttttc taattcatta acatgagtta agacttgttc
     8101 gagaatacta aaaacatgaa ggtcatctaa actgtaaagc atactttttc cttctcttct
     8161 tgatttcact aagcgtgcgt ctttcaacgt ttttaattga tgagaaatag cggactgttc
     8221 catgtccaga gaaatagcga tatttccaac actacactct tttttctgta aaagaaagag
     8281 aaccgacaat cgtgtaggat cactaatcac cttaaatagt ttgcttattg acagaataga
     8341 tcctttatcg attggagaag ttgtttttat atccatagtg tttttattcc tttcatatga
     8401 ccttccgttc atatctatat taccatatga gcgaaacaat gctaatcttt tgtttataaa
     8461 agagaagtgg cgttctcttt atcttgacaa aatgtatata gcgatataaa atgagtatac
     8521 aaacatatga ttaattagtc atatgtaagg tggattcatt acgatttact tttggaataa
     8581 acgaaaggag tcagaaatag cagaaattta tgtgattcaa gaagtaaatg atggaaaaca
     8641 aaggaattat aaattatata gggaggcaat agaagtggaa actatccaag aacaacagtc
     8701 tcaagaaaag cataatcata atcacaacca cgatcacgac catgatcatg ggaaaatgcc
     8761 agtcgttttg tactttgttg gtttagcatt agcagtgatt gctctatttt tgaatgaaga
     8821 ttatcagttg gtacaaaatg ttttgttctc aatcgctaca atcagtgccg ggtatcacgt
     8881 tattcttctt gaaggccttg gagaaacaat tgagaattca aaagcacaaa aaaagttcat
     8941 acctaattct catattttaa tgggattagc ggcaattgga gcttctttga tggggaattt
     9001 ttgggaagga acattattga ttcttatttt ttctggcgca cattttttgg aagattatgc
     9061 agaaggaaga agcaaacgag aaataacgaa attactcgaa atgaatccaa cgactgcccg
     9121 gttaatcctg cctgatggta gtacaaaaaa tgtggatgtc agtgaattaa aagtgggaga
     9181 tcaacttcaa gtgttgaatg gcgatcaagt acctattgat ggcgtcattt tgtctggatc
     9241 tacatccatt gatgagtcgt ctattactgg agaaagtatc ccgaaagaga aatccaaagg
     9301 agatggcgtc ttcgggagta caatcaatgg aacaggtacc ttcacgatga aagtcaccaa
     9361 agaaaacaaa gatacagtat tttcaaaaat tttacaatta gtgaatcaga accaagataa
     9421 ccaaacaaaa gctgcgagta ttatccaaaa atttgaaccg aaatatgtca cagttgtttt
     9481 aattgccatt cctctattca tgttattggc tccttttcta cttgattgga catggtcaca
     9541 aagtgtctat agaggattgg tccttttagt tgcagcttca ccgtgtgctt tagcagcagc
     9601 tactgtctcg gcaacgctat cgacgacttc taatttagcc aaaaaaggag tcctttcaaa
     9661 aggtagttct tacctgtctc aattagccga tattaaagca attgcatttg ataagacggg
     9721 caccttgacc aaaggaaaac ctgaagtaac caattattat tttgctgatt ccgtgaacga
     9781 agaaaacatg attgatatcg tagtagctct tgaaaaagaa tccaatcacc ccttagcaga
     9841 tgctattcta agaaagtttg agcaaaaaaa caaactaact attgaagtag aaaaccaaat
     9901 tggtaaagga ttgacgggag attacaaagg gagaaattat cgtataggaa aaccgacttc
     9961 gtttgatgat gtttcagatg aatatagtcg tttaaataat gaatgggcgt cagaaggtaa
    10021 gacagtcgta tacgtagcag tagatgaaga ggttataggc cttattgccc ttatggacgt
    10081 tccgagtgaa tatgctaaag aaaccattga atattttagg aaacaaggta tacacaccac
    10141 attaattact ggtgactcag aaatgacggg aaaagcggtt gctaaacaat taggaataga
    10201 tgaagtgatt gcgaatgtca tgccggaaga caaatccaga attatagacg aacaaaaaga
    10261 aaaatacggc gtgaccgcca tggttggaga cggtgtaaat gatgctcctg ctcttgttaa
    10321 tgcagatgtg ggaatcgcta tgggagatgg gactgatgtg gcagtagagg tatctgattt
    10381 agttttaatg caaaacaatt tatctaaatt ggtacaatct cataatattt cttcgaaaat
    10441 gaaccgtgtt atttggcaga atattatttt ttcaatggcc gttgttgctt ttttaattgt
    10501 cgttagtttc ttaggcttaa cggatattgc aatcagtgtc attattcatg aaggaagtac
    10561 tttggttgtt attttgaatg gacttcgatt gctaaaggca gtctaaagaa tgattgcaca
    10621 acttcaaatt aatcgagtaa tagagataat taaggattac actacatttt ttatctctat
    10681 tacttgttta tatttatcta gatgttcaaa gtcaaaatga tatatcaacc atactcttgt
    10741 ggcgcgggtt gaatataaga tacatgaaat tggataaaat catgtatcaa gaatcctatc
    10801 cttatagggt tctttttttt tactccccct aaacacacga tttcgtgttg taataactat
    10861 aatcatgtat tcgaacagac taaaaaggag ggattgtcat gggctataat gttcagccac
    10921 tacggtcgca acaggagatt aatgattttt tattttgcct gcgacggaat aaaaatgcgg
    10981 aacgtgacgt tttcttgttt ctaattggaa ttaacagcgg tctgcgcatg tccgacatcg
    11041 ttaaactcaa gaaaaaagac gtgattacct caaaaaaccc gcgcatcgtg gagcaaaaga
    11101 cagggaaaac acgcatttta tacttaagca gcttacagga cttgattcac ggctataccg
    11161 cacccttaga tccggaggct tacttgtttc ccagtactaa gggcggccat ttagaagtca
    11221 atacggtcta ccagatgttt caaaaggtcg cgaagctgtt aggaagggac gatatcggca
    11281 cccacaccct acgaaaaacc tttggttacc actattacaa gaaaaccaaa gacgtggcca
    11341 ccttaatgga aatctttggt cacagcagcg agaagattac caaacgctac atcggaatta
    11401 atgaagatga aatcagtgaa acgttattaa attttcggtt aggtttttga ttgtattata
    11461 taatagataa gcacagtaag acggttataa tcacccacag tattggacaa atcaaccttt
    11521 ttttggtata ttatatatac aaatgagagc aggctcatag tcaacttgat ataaatccgg
    11581 aacataaggg tccggcgggt ggcgagcacc aaaactaaac tcgatacaaa tccggaacgt
    11641 aagggtccgg cgggtggcaa gcaccaaaac taaacctgta caaaaggctg ctcttttgag
    11701 cagctttttt tattgggaaa aaggagcatt cttcgcacgc ggcaaaaaaa gaatacaaac
    11761 gcatgtctat aaaagagaca acccaaatta ccagacagtt aaacgcgatt tataaggctg
    11821 ctcatctctt acaagaacat tttgtagata aaaaagtatc ctttgtcgga gaagtctcaa
    11881 cggtagcgat tattttttcg acaactaatt ttatgcacct ctgtggcatt gattatcgca
    11941 gaggcacaca cttgtttttt caagatgcct tagacaggaa aataaattta caggatattc
    12001 aaatcaaaac ggatgggacg acctttcaga aattacaagt aataggtagc cttgatttat
    12061 tattggggaa gcatatttct attgttggca gaggtgttta ctcttctctt cgctatgatg
    12121 cagctattcg aacaaggaaa aaaatattgg ctctgtcttt gaaacaaaac ggattaatct
    12181 atatccctat ctctttgtta aacctatcat caaaggaaat tggacctgga caaaaagtta
    12241 ctggcatttt tagcgaggat ttaacatccg gggaacttaa aatgattatg gaagtcatcg
    12301 attaatcatt aatagtgata tgcgacgtca ttttgaagta attattctat tttgggttat
    12361 aaaataaagc attttaagac gatttcaaat cattcatgtg ggttatttat cacggatgag
    12421 cttgaaatcg tcttttatac gtatcaaatt gaaatgttcg gcatacaacc tatcgttgtt
    12481 actacattac taattgtcac ttgttaagga acttggatcc tttctaaaca ttccctagag
    12541 ataaatttta ctttatccct ccgttaatat ccaatttaag cacctttccg attcagggtt
    12601 aatttgcata tcaagtgcag cttgtgttct agtaagatta gcccttttag tccggctgag
    12661 ttgacttatg gatataagat atggtcatag caaatagata ctacgtatag tctgttaatt
    12721 tagtgtcatt aatcttaagt tggataggct acaattaact agacagaaaa attaaggtgt
    12781 gtagactaga agaaaacata ccaggaggaa tttttatgtc taagagaaca cgaagaactt
    12841 tttcacaaga attcaagcaa caaatcgtca atctttactt agctggaaag ccacgtgtag
    12901 aaatcattcg agaatatgaa ctaacggctt cagcatttga caaatgggta aagcaatcta
    12961 aaacgagtgg ttcattcaaa gaaaaagata atcctacgcc tgaacaaaaa gaattgttag
    13021 aactacgtaa aagaaaccag caattagaaa tggaaaatga tattttaaag caagcagcgc
    13081 tgatattcgg acgaagagac aagtaatcga tgcgaataag catctttacc ctatatcagc
    13141 gatgtgcaga atattaggtc tatcacgtca gtcctattat tatcaatcaa aaccaaagaa
    13201 agacgaatca gaacttgaag aagcagtcgc tgaagaattt atccgcagcc gaaaggcc
//
LOCUS       DADVXM010000065        13148 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.068, whole genome shotgun sequence.
ACCESSION   DADVXM010000065 DADVXM010000000
VERSION     DADVXM010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.068"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(79..151)
                     /locus_tag="KB927_002030"
     tRNA            complement(79..151)
                     /locus_tag="KB927_002030"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(116..118),aa:Lys,seq:ctt)
     gene            532..1101
                     /locus_tag="KB927_002031"
     CDS             532..1101
                     /locus_tag="KB927_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBB6840939.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1088..1948
                     /locus_tag="KB927_002032"
     CDS             1088..1948
                     /locus_tag="KB927_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6840940.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2138..2842
                     /locus_tag="KB927_002033"
     CDS             2138..2842
                     /locus_tag="KB927_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6840941.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2847..4682
                     /gene="walK"
                     /locus_tag="KB927_002034"
     CDS             2847..4682
                     /gene="walK"
                     /locus_tag="KB927_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBB6840942.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4679..5995
                     /locus_tag="KB927_002035"
     CDS             4679..5995
                     /locus_tag="KB927_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840943.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5996..6865
                     /locus_tag="KB927_002036"
     CDS             5996..6865
                     /locus_tag="KB927_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBB6840944.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6920..7729
                     /locus_tag="KB927_002037"
     CDS             6920..7729
                     /locus_tag="KB927_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6840945.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7832..8461)
                     /locus_tag="KB927_002038"
     CDS             complement(7832..8461)
                     /locus_tag="KB927_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBB6840946.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8631..9923
                     /locus_tag="KB927_002039"
     CDS             8631..9923
                     /locus_tag="KB927_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6840947.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9999..10661)
                     /locus_tag="KB927_002040"
     CDS             complement(9999..10661)
                     /locus_tag="KB927_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6840948.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10886..11170
                     /gene="groES"
                     /locus_tag="KB927_002041"
     CDS             10886..11170
                     /gene="groES"
                     /locus_tag="KB927_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBB6840949.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11221..12846
                     /gene="groL"
                     /locus_tag="KB927_002042"
     CDS             11221..12846
                     /gene="groL"
                     /locus_tag="KB927_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBB6840950.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4371 a         2265 c         2833 g         3679 t
ORIGIN      
        1 aataaaaaaa gaacagcgta aatgttttcg aaatgctttc gcaccaacat ttacctgttc
       61 cgtgggtttg gcacccaatg ggccgtgagg ggctcgaacc cgcgacccgc tgattaagag
      121 tcagctgctc taccaactga gctaacggcc cgtacaaaaa gtacttaata atagtagcac
      181 taagaatttt aaaatgcaag actacattta aagaaaatca gaaaaatctt tacttcctta
      241 taggaaatca ttcatagatt attcacattt gctcgctatt atataagcat accaacaaac
      301 aaagttcttg caagagaaca aaccctaaca cttttttcat tttttactcc tttcccgccg
      361 tctccccggc gggtctcctg ttcttaacga taaaagacaa gaaggcttag ccttcttgtt
      421 ttttgttttc atggaatccc gctaatcaaa tcacctagtt aaagcaacta gattgaatgt
      481 ttatcataag tctgatatca tgtttatgaa atgaaaaaag gagcggttat gatggaaaaa
      541 atgcgtcagc aattaatgga gtgggggaag gaactagaaa cattccgtct gcctcactgg
      601 gaagaactcc ctgacttaga actttatatg gaccaagtca gaacgttagt tgatcgttat
      661 ctttcacctg tgatacaagg agaaaagcat ccattgctta cctcttctat ggtaaacaat
      721 tacgttaaac taggtttgat accagcacca gttaaaaaaa gatataacaa agaacacgta
      781 gcatttttac ttgcaatcac tacgttgaaa caagtattga ctattcctga aatcaaagaa
      841 gggatattgt tccaaggaaa aacagtagga attcgtgaag cctataatct attttgcgat
      901 gaacaagaag cagctgtgtg gatggtcagc caattagcac aaggtaaatc tcatccgcaa
      961 aaattcgacc aggcaacccc tgtagaatat attgctgtaa gagcggcaac tttatcgttt
     1021 gcaatgaaac ttcttgcgga aaaaacgatt gttctagaaa ccgaatattt aaaagaggag
     1081 aaaacaaatg aaaaacaata aaatcgcaat tttagtagat tcaggtacgg atgtgccaga
     1141 agaattgata aaaaaatacg agatgtatat gatcccattg aaaattattt ataaagatca
     1201 ggtatataca gataaaattg acattacctc tgaagagatc tatcaacgtt tgccagagga
     1261 aatccctggt acatctttgc cggatggtga gtcgatcaca gaaatctttg agcaaatcaa
     1321 aaaagacggt tatgaaaagg tacttgcggt aacaatttcc agtggattga gcgggacata
     1381 taatgtggtt cgtttaattg cacaacagca agaagaattg gaagcatatg tactagatac
     1441 gaaaaatatt ggtattggtg caggtttttc tgcgatccaa gcagcaaaat ggctggaaga
     1501 aggagtagaa tgggatcaac tgatcagtaa tctgaatgag ttagtcgaaa gaacaaaagt
     1561 tttctttaat gttgcgacat tggaatatct tcaaaaaggt ggacggatcg gtttagttgc
     1621 ttctattgta ggaaccgctt taaagcttaa cccaatcatc tcatgtaatg aagaagggat
     1681 ttattacaca gtaggaaaag ctaggggacg taaaaaaagt ttggataaaa cggttgctta
     1741 cgtcaaagaa aaaatcggta atgcaaaggt cttcaactta gctgttgccc atggggatgc
     1801 gaaagaagaa gcaattgaaa tggaagcgag acttaaaaga gagttcccac aagcaaacca
     1861 aatctacttt ggccagattt ctccggcatt agtagtccac actggtccgg gattattggg
     1921 tgtcggtgta caagttttag aaggataaat caaaaaaagg aaacactgag gtgaaaatca
     1981 gtgttttcct tttttattga agttagaaca aaaaataata aagtattttg cactttcatt
     2041 ttaattttct cttttgtttt ataggcaaag atgaaacaaa agcagaaata cggtataatg
     2101 agaaggtatg acaataatat ataagaggtg gctctttatg aaaaaagttt tagttgtcga
     2161 tgatgagaag ccgatttcgg atatcgtcaa attcaattta gccaaagaag gctatgatgt
     2221 ttatactgca tatgatgggg aagaagcctt ggaaaaagtt gctgaggtag aacctgattt
     2281 gattttactt gatttgatgc tacctaaaat ggacggctta gaagttgctc gtgaggtacg
     2341 caaaacttat gatatgccga tcattatggt aacagccaaa gattctgaaa ttgataaagt
     2401 cctaggctta gagttaggcg ccgatgatta cgtgaccaag ccattttcca accgagaatt
     2461 agttgcacgt gtcaaagcaa atcttcgtcg cggtgccacg gctgcgaagg aaccagaaga
     2521 ggcagcacct gcggaattga cgattggtga tttgacgatc catccagaag cttacatggt
     2581 gacgaaacga ggagaaacaa tcgagttaac acatcgtgaa ttcgaactac tcttttactt
     2641 ggcgaagcac cttggacaag tgatgacaag agaacattta ttacaaacgg tttggggtta
     2701 tgattatttt ggagatgtac gaacagtgga tgtaactgta cgtcgtttgc gtgaaaagat
     2761 cgaagataat ccaagccatc caaattattt agtgacacgt cgtggtgtcg gttactattt
     2821 gcgtaaccca gaacaggagt aattggatga aaagaaaagt ccgctttttt cgatcagtca
     2881 attttaagat cgctattacc tttattctga ttttattgat ctcgatcgaa attattggtg
     2941 cctactttat acgtggttta gaacgttcca cgatcaatac atttattaaa gatatgaatc
     3001 aaacggtgga atcattagca acaacaatca gcccggaatt gaatcgaaaa gataatgcag
     3061 atgatgaaga ggtaaatgcg aatatcaaaa gatttattga aaacagtgcg actagcgata
     3121 tcatcgaaat acgggtcgtt gacgaaaaag ggatcatccg aggaacaacc gatgtcaatg
     3181 aacaaagcgc tgtgggaaag aaaaatgatt atgttgatat caatgatttc acgactaaac
     3241 gttatgttgc tttagataac gacgataaac gggtgaatat caatgttcaa ccgatcctgt
     3301 ccccgaccgg cgatgccgtt atcggggctc tttacgtcaa aagtaatatc gaacaaaaat
     3361 attcggaaat caataacaca gcagtcattt tctttactgc ctcactaatt gcggcattta
     3421 tttcaatgat cgtatctgtt ttagttgctc gttcgattac acagccgatc ggtgaaatga
     3481 gagaacaagc cattcgaatc gctagaggag actacagtcg gaaagtcaaa gtgcatggac
     3541 aagatgaact tggacagctg gctgatacct tcaatcagtt agctgaacgt attgaagaag
     3601 ctcaagatac aatggaagct gaacgcaatc gtttggatag cgtgctatcc catatgacag
     3661 acggcgtcat tgcgacagat cgcaggggta aagtcattac gatcaatgat atggctgttt
     3721 ccttgctaga tatcaaaaac gaggaagcaa tcggacaatc gattttgaca cttttagata
     3781 tcgaagaaga atatacgttg cggaaattat tagaagatcc aaacgaaatg gtacttgacc
     3841 gttcaaccag tacattggaa agtgatcaga tgatcttgcg agtagacttt tctatgatcc
     3901 gtcgcgaatc aggttttatc agcggattag tagctgtctt gcatgatgtg acagaacaag
     3961 aaaaaacaga acgggaacgt cgtgaattcg tctctaatgt ttcccatgaa cttcgtacac
     4021 cgttgacaag tatgcgtagt tatatcgaag cattgagcga aggtgcgtgg aaagacgagg
     4081 aagtagcacc aaattttttg aaggtaacgc tagatgaaac agaccgaatg attcgaatga
     4141 tcaatgacct cttaaatcta tctcgcatgg atacaggtaa tacccagctt caattagaat
     4201 atgtcaattt caacgagtta gtgaattttg ttcttgaccg gtttgatatg atggtgggaa
     4261 atcaggaaaa aaattataag atccgtcgtg aatttacgca aagagatctt tgggtcgaag
     4321 tagatacaga taaaatcatc caagtagtcg ataatatcat gaataacgcg atcaagtatt
     4381 caccagatgg gggaacgatt acttgtcgct tattagaaac gcataataac gtggttttaa
     4441 gtatcaccga tcaaggattg gggattccta aaaaagatct gaaccgagtg ttcgagcggt
     4501 tctatcgagt agataaagca cgtgcaagag cacaaggtgg gacaggactt ggattagcta
     4561 tttctagaga agtgattaag gcgcatcgag gcgctatttg ggcagagagc aaggaaggaa
     4621 aagggtcgac tttttatatc tcgctgccat atgaacctta tgaggaggaa tggtgggaat
     4681 gagaatctct gaaaaagtcg ttcgtatagg actcattttg atggttgcgt taagcatata
     4741 cttctcttat gcaatctggc tgagcccagc aggaaaaagt tcaatcaacg tagatgagac
     4801 aaacactcaa atgatcgagt ctcaaagcaa tcgaaaaact tccgaagtct ttcttccgct
     4861 tcatgttaca tggcaccatt cgggaatgat ccaagaaacc aacagtgaaa atctcgtgta
     4921 ccgattgcaa ttgatcatcg ataaagcaag atttggaaag ctttctgaag tagtttcagg
     4981 agacaaatca cagtttgaac aggtgaaaaa tctgaactct ggttttgagt tggcctataa
     5041 tgcgcctttt ttgctaagag aatacaagga agcatttgat ttagatttag atgtgtcgaa
     5101 cttggcaaaa gaaagcgaaa atatgtattt tactagaata caattcgatc aaggaaataa
     5161 aaaaatccga tttttgaatt attcgaacca tctcgtatat gaagcaaata tttcgttgaa
     5221 ttggacagat atcaataaag aattaacagc aaaagacaca aaatggacag aaatgacaac
     5281 agaaccatcg acgatcgaca cgcaatatgc tacgaaacat tcgatcaaac tgaaaaagta
     5341 tagttatatc ctgtcacagc aaccctatac actttttaga aatgcttttt tccagaaacc
     5401 agatagcgtg aaaaataatg atgaaagcaa tgaattgatt ttttacggtg ggaatgaaac
     5461 aatgtctatc cattcggaaa cgcaagtagt tgattttcgt ggagagctgc cagagaaaaa
     5521 agaaaatgct agtgtatttt ctgaaagttt cccctatatt agcaaattag gcagttcttt
     5581 agggaacctc agatattttg accgcagtga caatacgatc gattatcgga tattcgtgga
     5641 aggcttcccg gtttttggga cagacagcag aggacagatt ggtgtggaag ttggcggtga
     5701 aacgaatggt tctgtgcaag tgaatatcca aaccagtttg aatacgattc aagtgccgat
     5761 accttcagac gaagaagtag aacttgcaag tacgaatgaa atcatccagc agttaaaagc
     5821 taagggagca gatagcaaca agattggttc agtgatcgtt ggctatacat ggcaaaatgt
     5881 caaagaaacg aatcgtgtcg ttgatctctt acctgaatgg tatgtgaaat ataaagataa
     5941 ctggtattca gctaacgacc ttctggaaaa attacctgga ttggaggcga attaattgga
     6001 tttcaaaaaa atcgaatgga tatttttcgt cgctttttta gggttgaatg tgtttttatt
     6061 cagcagttat catgacgcgg tataccaaga aaacaatgtc attcgctcta atcagactga
     6121 atcaatccaa caacgtctgg ctagcgacga tatcacttac acggggaaga tttcgtctga
     6181 gaacaagcaa ggctattatc ttagcgcgga gcagaccaat cttagcactt cattagcgaa
     6241 ttatcgcaag gctggtaaaa gcggcttgct ggcaagtggt gtgtttttag acggtgatgt
     6301 tttgacgaaa tctttatcca gttcagatgc tgaaaagaac gtgatcgatc cagataaaat
     6361 tagtagttcc ttggaagatt ttttatctaa caaagacaat attttattcg gtaatgatta
     6421 tgtgtacacg aaaaactttt ctcatttaga agaagaacca ctagaaatcc aagcaagcca
     6481 agagtatgaa ggcatcccat tcaatgatga tacagcaaaa atcgttcttt ctttagaaaa
     6541 aaacgataat gattatagca tcacgaaata catgcagacg catttatctg atatcgagca
     6601 gctgcgcgaa aagacggaac tgtatacgga agaggaagca atcaatacat tgtacatcaa
     6661 taacaaaata ccaagaggat caaaaatttt atggcgtcag ctagcttatt cctgtattct
     6721 gaaagtccgg gaaaaaaatg tgtatgttcc tgtttggcat gtagcgatcg aaacaagcga
     6781 taaagtggtc caaattgaga gtgtcaacgc tttcagcaat acgatcgtga caaacaatac
     6841 tgtaccaaaa gtggaagatc aataaaaaag cgagtataat gaaaaaagtt tacaaagtaa
     6901 gaagggaagt aggagtcaaa tggctgaaga aaaaccagct tttaaaatca gtatcctagc
     6961 aagtggaagt tcgggtaatt cactttatat cgaaagtgaa aaaaaacggc ttttggtcga
     7021 tgcaggactt agcggtaaaa aaatcacttc cttgatggct caaattgatc ggacaccgga
     7081 ccaattagat ggaatacttg tgacgcatga acatcgagat catatacatg gcgtgggtgt
     7141 cttggctcgt aagtatcatt tggatgtttt tgccaatcag cagacttggg aagcgatgga
     7201 accactgatt ggaaatgtac cagtggaaca aaaacatcta tttgagatgg ggaaagtcag
     7261 aacattcggc gatatcgata ttgagagttt cggcgtctcc catgacgcag cggctccgca
     7321 attttatcgt ttccataaag aaaatcggtc attcgtcatg ttgacggaca ccggatattg
     7381 cagtgattat atgcgaggtg tcattgaaaa tgccgatggt tatttgatgg aaagtaatca
     7441 tgatcttgag atgttacgca tgggacctta tccgtggaat ttaaaacagc gtattttagg
     7501 agatagagga catctttcca acgaagacgg tgcacttgtc atgactgatg tgatcggtaa
     7561 tcggaccaaa cgaatctatc ttggccatct tagcaaggaa aacaatatga aagaacttgc
     7621 tcatttaaca atggaaaatg ttttgaaaga aaaagatttt ggcgttggac atgattttga
     7681 aatctatgat acagatccag atgaagcaac tgagctattt tcgatttaaa cagttcaatc
     7741 aataaaaata taaaaagcag aagataaaat caatcagggt tggttttatc ttctattttt
     7801 atttttttag catattaaaa aaataaccgt attatcgact gactacactg atgtgctgct
     7861 tttcatgttt ctcatccagt atctcatcta ctaatgcaat cgcgtaatct gccatgctga
     7921 tcgtactgtc gccagcagcg tttctttgta aataatcatc acttaacaaa taagtacctg
     7981 tacgtttgcc atgtggatca aataaagaag ctggactgat ataagtccaa tgtagatttt
     8041 tagattgttt caattttaac aatccttcgt acatattgaa agctgttgga tagaagggtg
     8101 catttttagg tacttggtca atcatacgag tcgtcttttc tgtatctaag aataacgaag
     8161 aggcaccccc aacgacaatt aagcgtgtat cggttccttc aagcatctca atcaaatggg
     8221 acaaagaagt ttgatgcatt tcttcttttc ctttgggagc gttgaaagca tcaacgacaa
     8281 catcaaaaga tgcaagatca gtagttgtca actcaaataa atccttttgt ataaacggaa
     8341 catctgatgg caatttttct ggatgacgca cgattgccgt cacgtctaaa tctctggaca
     8401 atgcttcgtc taaaataaat gaacctgcat ggccagtagc tccaatgagt gcaattttca
     8461 taaaaaacct ccttttttat tcctgtccat tgtaagcagt tgctgaatat tcgtcaaaga
     8521 atccgatttt tgaaaagctc agtgcgcatt cctttcatgg ttcgtgatca ttgggtatag
     8581 ttaaattaag aaaactgatt gataaaaata gaagttgaag gagataagaa atgaaagagt
     8641 ggttagatcg tgccttttta ccaatgataa catctgttgt gaatcttaga cccttaactg
     8701 ctttgcgtaa tggaatgact tacacgatcc caataattat tgttggctcg ctgtttttct
     8761 tatttgctca ttttcctgtg gattacatcg ctcagtggat agacaaaaca ggattttcta
     8821 tgtattttac acaagtatac caggctacat ttgatgtgat agccttttgg atcgtttttg
     8881 ccattgcata cgcttatgca aaagaagaag acatcgatcg cttaccagtc ggcataacag
     8941 ccttgtctgc ttatctactg cttattcagc cactaaatac tcagatagat actgtctgga
     9001 caggtgctga agggatacta ggagcagtta caactgggct catcatcgga tggggctatg
     9061 cacgtttagt aagacttgcg aaagggtgga agcaaagaga gaagatacct gaaaatgttt
     9121 ggcagtcttt tacttcattg attccaatca ttgttatagt cacttttacg cttatcggtt
     9181 cagcggtttt tcaacagttg ttcagaatga ctgttgttca aggagtatgg acatatgtcc
     9241 agcttcccat tcaatcgttc atagacacgt tgtttggtgt gcttttatta ggtttttttg
     9301 ttccgttttt atggttattt ggtcttcatg gatctgcgat ggtcaatggg ttggttagtc
     9361 ccgtcttgca agcgaattca ttagcgaatg cagaaatctt agcctcagga caagagttga
     9421 cggtggcaaa tggcggacat atcgttactc agcaatttct cgatcagttc atgacggtta
     9481 cgggtgctgg attgacgtta ggggctgtat tttttatgac ggtttttgcg aaatcgaaga
     9541 aatacagaga attaggaaat cttgctcttt taccagcctt tttcaacatc aatgaatcaa
     9601 ttattttttc cacaccgatc gtgatgaacc cgatgatggc tgttcctttt attttcgcac
     9661 cggtcgtttc aggattgatt acctattccg ctttatattt tggattcgtt cctttattta
     9721 cagcagtcca agtcccttgg acaacaccgc cgatcctctc gggtttctta gtaggcggag
     9781 tgcctgcagc gattttacaa ggtatcgtgt tgtcaattag ttttttcatt tatttcccat
     9841 ttttgaaaaa aatagattct gcaaactgca aaaaggaaag acagacaaaa aatgatggag
     9901 cagcagaaaa gatgaacgac taaaaaacaa aaatactcct gtcgctttag attgggaaaa
     9961 tcaccaatct aggatgacag gagtatttat agtcatgttt atactagccc tttttggaca
    10021 gctaattgaa caagaacaac taatgtgttc attcctacgt gtgtgatcat cgatgtccag
    10081 atccgaccag ttgctttgta ctctaggctg aagaagaaac ctaggaaaaa gtagattagc
    10141 agatgaccat cattatgagc aaacgcaaac agcaaagagc tgatcactgc tccgacccaa
    10201 aaatttgaat atcgactgat gatccccagt atactgcggc ggaatacgaa ctcttccatg
    10261 atgggtccag caacagttgt cgccaaaata aaagcgggtg cttccatgat catctggatg
    10321 atattttgtg tattctcgga aggggttgct ttgccaaaca atacagattc taacatgaca
    10381 gcgatgcttt gcagaatcaa tgcgacaaag attccaacca atccataaat aacaatcttt
    10441 ggagcagaag ctttttttac cgctgattcg atcgctaagg gttcacgttg cttaaaataa
    10501 aaaatagcta ggacaacggc gcctagtata tacatgactg cagttgctgt gatcaattca
    10561 gacgtagatt ttacaagtcc tatcgaagct aggatcaagg gtgagataaa aattagacca
    10621 tagcaaaaaa tgctgaggaa gctatatttt tttaaagaca tgtaattcct ccttttaagg
    10681 gataacaagc atgcaaggca agcttatatc gattgatttc aattatatca taatttcaat
    10741 aagcagctgt cagaataaaa tttcttttct ttgatttaaa agcttgcaaa aaagagggag
    10801 aatgagtatt attaaaaatg taggttagca ctcgaaggtt aagagtgcta acagattaaa
    10861 aaaagagtta tcggagggat ttatcgtgtt aaaaccatta ggtgatcgcg tcattatcga
    10921 agtcgcaaaa gaagaagaaa aaactgtcgg aggaatcgtt ttagcttctg ctgctaaaga
    10981 gaaaccccaa actgggacag ttgttgcagt cggtgaaggc cgtttgttag aaaacggtga
    11041 aaaagttcct gccgctgtaa aagcaggcga ccaagttatg ttcgaaaaat acgccggtac
    11101 agaagtaaaa tacgaaggaa aagaatatct gatcgtcgca ggaaaagata tcatggcgat
    11161 tgttgagtaa atttggaaga taaaaaaata atcaaaaata atcaatgagg tgaatcaatc
    11221 atggcaaaag aattgaaatt tgcagaagac gcacgcgcag ctatgttacg cggggtagat
    11281 aaattagcag atacagtgaa agtaacatta ggacctaaag gccgaaatgt cgtactagaa
    11341 aaatcttacg gctctccatt gatcacaaat gatggtgtga cgatcgcaaa agaaatcgaa
    11401 ttagaagatc attttgaaaa catgggtgca aaacttgtat cagaagtagc atcaaaaaca
    11461 aatgatattg caggagacgg tacaacgaca gcaactgttc tgacacaagc aatcgttcgc
    11521 gaaggtttaa aaaacgtaac tgcaggtgct aatcctctag gcattcgtcg cgggatcgaa
    11581 ttggcaacaa aagcagcagt cgaagaattg cataatatct caactgttgt tgattcaaaa
    11641 gaagccattg cacaagtagc agctgtttct tcgggttctg ataaagttgg acatttgatt
    11701 gctgatgcaa tggaaaaagt tggaaacgac ggtgtcatca caatcgaaga atcaaaaggg
    11761 atcgaaacag aactagatgt tgtagaaggt atgcagtttg atcgtggtta cttatcacaa
    11821 tatatggtaa cagataacga caaaatggaa gctgttctag aaaacccata tatcttgatc
    11881 acagacaaaa aaatctctaa catccaagat attctgccat tgttagaaca aatcttgcaa
    11941 caatcacgtc cattgttgat tattgctgac gatgtagatg gtgaagcatt gccaactctt
    12001 gtattgaaca aaatccgtgg aacattcaac gtagtagctg taaaagctcc tggtttcggc
    12061 gatcgtcgta aagcaatgct tgaagatatc gctattttga caggtggtac agtaattact
    12121 gacgatctag gtttagaatt gaaagatgta acaatcgaaa acttaggaaa tgcttctaaa
    12181 gttgttgtag ataaagacaa tacaacgatc gtagaaggtt ctggagaaaa agaagcaatc
    12241 gaagctcgtg tgcaattgat caaaaaccaa attgctgaaa caacttctga ttttgaccgc
    12301 gaaaaattac aagaacgctt agctaaatta gcaggtggtg tagctgttgt taaagttggt
    12361 gcagctactg aaacagaatt gaaagaatta aaattacgca ttgaagatgc attgaatgct
    12421 acacgtgccg cagtagaaga aggaatggtc tcaggtggtg gtacagctct agtgaacgtt
    12481 atcagcaaag tttctgctgt agaagcagaa ggagacgtgg caacaggtat caagatcgtt
    12541 gttcgtgctt tagaagaacc aattcgtcaa atcgctgaaa acgctggtta tgaaggatca
    12601 gtgattgttg ataaattgaa gaacgtggaa ctaggcactg gtttcaatgc tgctactgga
    12661 gaatgggtaa acatggttga agcaggtatc gtagacccaa ctaaagtaac acgttctgcc
    12721 ttgcaaaatg ccgcttccgt ttctgccttg ttattaacga cagaagcagt cgttgcagat
    12781 aaaccagaac cagcagcgcc agcagctcct gcaatggatc catcaatgat gggcggtatg
    12841 atgtaagaaa aagcaacttg cttatctaca actgatcatt agtgaaagac agataaaaag
    12901 aggctggaac agaagcgttt aactccaaga aataagaaga aattcacgga aattgctttt
    12961 caaatttttg tgaatttcag cttatttccg aaggagttgc ttctgcttcc gctgtttata
    13021 cgtgtttaga gcgtgagaca aaagtgttct ttacttttgt cccacgctct tttttgtgtg
    13081 taattataat gaaaatagtt atttttaata gttataatat tttatctatt aaaagtaaat
    13141 atccattc
//
LOCUS       DADVXM010000066        13085 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.069, whole genome shotgun sequence.
ACCESSION   DADVXM010000066 DADVXM010000000
VERSION     DADVXM010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.069"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(78..2198)
                     /locus_tag="KB927_002043"
     CDS             complement(78..2198)
                     /locus_tag="KB927_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6840951.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2428..3606
                     /locus_tag="KB927_002044"
     CDS             2428..3606
                     /locus_tag="KB927_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBB6840952.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3622..4380
                     /gene="aroD"
                     /locus_tag="KB927_002045"
     CDS             3622..4380
                     /gene="aroD"
                     /locus_tag="KB927_002045"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBB6840953.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4403..4888
                     /gene="ybaK"
                     /locus_tag="KB927_002046"
     CDS             4403..4888
                     /gene="ybaK"
                     /locus_tag="KB927_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBB6840954.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4959..6212)
                     /locus_tag="KB927_002047"
     CDS             complement(4959..6212)
                     /locus_tag="KB927_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6840955.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6328..7677
                     /gene="gdhA"
                     /locus_tag="KB927_002048"
     CDS             6328..7677
                     /gene="gdhA"
                     /locus_tag="KB927_002048"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBB6840956.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7789..9135
                     /locus_tag="KB927_002049"
     CDS             7789..9135
                     /locus_tag="KB927_002049"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBB6840957.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9443..9829)
                     /locus_tag="KB927_002050"
     CDS             complement(9443..9829)
                     /locus_tag="KB927_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6840958.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(10097..10246)
                     /locus_tag="KB927_002051"
     CDS             complement(10097..10246)
                     /locus_tag="KB927_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840959.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            10708..10920
                     /locus_tag="KB927_002052"
     CDS             10708..10920
                     /locus_tag="KB927_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840960.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11198..12997)
                     /locus_tag="KB927_002053"
     CDS             complement(11198..12997)
                     /locus_tag="KB927_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBB6840961.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4291 a         2354 c         2577 g         3863 t
ORIGIN      
        1 tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctaatttt gtcgctgctc
       61 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
      121 gtttgcgttt tataaagatc aacagttgat tgtcccttgt gttcactaaa gacactagtt
      181 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
      241 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
      301 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
      361 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
      421 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
      481 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
      541 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
      601 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
      661 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
      721 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
      781 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
      841 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
      901 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
      961 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     1021 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     1081 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     1141 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     1201 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     1261 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     1321 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt caagctggag accattctca
     1381 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     1441 ttttttcctt tagcgagccc gaacaaatca tcatttggtg ctgcataatg ttcttttaca
     1501 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     1561 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     1621 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     1681 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     1741 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     1801 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     1861 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     1921 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     1981 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     2041 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     2101 aaataggcaa aaatcgtttt caaccaaagt aaaacaacta gtaaagaaaa aaatccgagc
     2161 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     2221 cttaatcaca gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta
     2281 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     2341 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     2401 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     2461 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     2521 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     2581 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     2641 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     2701 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     2761 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     2821 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag
     2881 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     2941 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     3001 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     3061 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     3121 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     3181 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     3241 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     3301 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     3361 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     3421 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     3481 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     3541 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     3601 cattagaagg agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga
     3661 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     3721 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     3781 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     3841 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     3901 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
     3961 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
     4021 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
     4081 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
     4141 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
     4201 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc
     4261 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
     4321 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
     4381 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
     4441 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
     4501 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcata tatttaaaac
     4561 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
     4621 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
     4681 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
     4741 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
     4801 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
     4861 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
     4921 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
     4981 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
     5041 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
     5101 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
     5161 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
     5221 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
     5281 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
     5341 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
     5401 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
     5461 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
     5521 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
     5581 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
     5641 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
     5701 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
     5761 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
     5821 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
     5881 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
     5941 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
     6001 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
     6061 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
     6121 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
     6181 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
     6241 tctgaagaaa gaaaacagaa aaaatgtttt gagccaaaag agaaaatgag ctaaaatgag
     6301 ggaagataag caaaggagcg tggaacgatg acaaacgcaa cagaatatgt tcaagcaatt
     6361 caagaaaagc tacatcaaaa ggatcaaggg caagaagaat ttttacaagc aatcgatgaa
     6421 ttcatgccca cggttatgtc ttttttggac actcatcccg aatatatcga aaagaatatc
     6481 ttagaacttt taacggaacc agaaagagtt attcaatttc gagtgccttg gcaagatgat
     6541 gaaggaaact ggcgagtaaa tagagggtac cgtatccaat acaactcagc tatcggccct
     6601 tataaaggtg gattgcgctt ccatcctagt gtcaatctaa gtatcttgaa atttttggct
     6661 tttgaacaga ttttcaagaa tagtttaacc ggtctgccaa tcggtggagg aaaaggcgga
     6721 agtgacttcg atcctaaagg aaaatctgat aatgagatca tgcgtttttg tcaaagtttc
     6781 atgctggaat tgtcaaaaca tatcggccca tcgattgatg ttcctgcggg agatatcggt
     6841 gtaggagcta gagaaatcgg ctatttgttc ggcgaatata aacgattgaa aaaatatgat
     6901 actggtgtgt tgacaggtaa acctttggat ttttggggaa gtaagatacg tacggaagct
     6961 actggttatg gattagtgta ttatgtcaaa catctattga acgaagaaaa agattcattt
     7021 aatcaaaaaa cagtttttgt ttccggaagc gggaatgtag ccatttatgc aatcgaaaaa
     7081 gtgcaagagc taggcgggaa agttgttaca tgttcagatt ctagcgggta catctatgat
     7141 ccagaaggaa tagatgtgaa actattgaaa gaagtcaaag aaatcaatag acaacgtttg
     7201 acggaatacg caaaccaacg tccttctgct atttatcatg ctggagaatc tgtttggaca
     7261 ttgaaagaaa aagcggatat cgctttgcca tgtgctactc aaaatgaaat agacgaaagc
     7321 ttggccgaaa tcttagtaga aaatgggatc aaaatcgtag cagaaggcgc taatatgcca
     7381 tgtacagtaa aagctgtttc tgttcttcat gaagcaggcg tgtggtattg tccaggaaaa
     7441 gctgctaatg ctggaggagt agcagtatct gctttagaaa tgagtcagaa cgcccagcga
     7501 ttgacttggg aaagagagca agtggatgag cagctggatc aaatcatgga aacgatttac
     7561 catacgtgtc gccaaacagc agccgagtac ggcgacgaaa aaaatctgct tcttggagca
     7621 aatgttgctg gatttgaaaa agttgccaaa gcaatggcag cagaaggttt agtttgaaaa
     7681 atgaaacttt cttggaaata ttgtcagcat tttgtttatt tgcttgaaaa ataataaaaa
     7741 aaaacgtaaa gtattacctg tagagtaaac ctataaggag gagaacaaat ggcacacatt
     7801 cattttgact attcaaaagt agcaccgttt gtcaacgaac aagagttagg gtacatgcaa
     7861 agccaagtaa cagcagccca caacgaatta cgggaaggta ctggcgcagg aagcgacttc
     7921 cgcggctgga tcgatttacc aacgaactat gacaaagaag aatttgcacg tatcaaagaa
     7981 gcagctaaaa aaatccaatc tgattctgaa gtattagttg ttatcggtat cggtggttct
     8041 tatttaggcg ctcgtgcagc gatcgacttc ttgaatcaca cattcttcaa tttattagat
     8101 agcaacacaa gaaaagcacc acaaatcttc tttgccggaa attcaatcag ctcaacatat
     8161 attgctgact tgatcgaagt aatcggtgat cgcgactttt cagtaaacgt tatttcaaaa
     8221 tctggaacaa ctactgaacc agcgattgcg ttccgtgtat tcaaagagct tcttgttaag
     8281 aaatatggac aagaagaagc aaacaaacgt atctacgcta caacagataa agcaaaaggt
     8341 gcagttaaag tagaagcaga tgcagaaggt tgggaaactt tcgtgattcc tgatgacatc
     8401 ggcggacgtt tctctgtatt aactgctgtt ggtttgttac caatcgctgt tagtggtgca
     8461 gatatcgatg cattgatgca aggtgccgct gatgcaagca aagcatactc aagcgacaaa
     8521 ctagaagaaa acgaagctta ccaatacgca gcaatgcgca acattcttta ccgtaaaggc
     8581 aaagtaactg agttgttgat caactatgaa ccaggaatgc aatacttctc agaatggtgg
     8641 aaacaattgt atggtgaatc tgaaggaaaa gaccaaaaag gcatctatcc ttcaagcgca
     8701 aacttctcaa ctgatttgca ctctttagga caattcatcc aagaaggacg tcgcaatatt
     8761 tttgaaacag ttgtgaaggt tgaaaaacct cgtaaatcaa tcacaattcc tgaacaagca
     8821 gaagatttag acggtctagg ctacttgcaa ggaaaagaag tggacttcgt aaatacaaaa
     8881 gcatttgaag gaacattgct tgctcataca gacggtgacg tgcctaactt gctagtcaaa
     8941 attccagaaa tggatgctta tacattgggt tatacaatgt acttctttga aattgctgta
     9001 ggtatttcag gttacttgaa tggaatcaac ccattcgacc aaccaggtgt agaagcttac
     9061 aagaaaaaca tgttcgcact tctaggcaaa ccgggctttg aagatcttgc taaagaattg
     9121 aacgaacgcc tgtaagataa gggtttttcg ctagatttaa ataatcagtg atagaaacat
     9181 gttcgcttta aaatgaaaac tggtacccat ttaggtactc aaacatactg catcgtttat
     9241 tcagaataag gggctgtgac aagacgtttg tcacagtccc ttgtttgtat agaaatcgat
     9301 tgattgcctt gctctttagt ttgttttagg actttaagaa cagtgaggct gacttcgaag
     9361 gttaattctg tttttttgtt ttctagaatc agtaagcaaa aaagcactca cttcgagtgc
     9421 ttttttgcga tatattctta gcttaagata ggcctaattt ttcttttaca gatgagggta
     9481 ccttatcgct ggtaattact tttttctcta tgatccgctt ttcgcttgct ttcaactgca
     9541 agatcgttcc ttcggtgtaa gcagaaccat tggcagagtc accagaagta atgacatcga
     9601 aatctaactg tcttttttca ccgttttcag cataagcatc tacgttgtat ttaaaacctc
     9661 ttccaattac ttccccatta tctgctttga tatcagtttc tgcaggcatt ggagctttga
     9721 ctaccgcata ataatcttta cctacataag tagactgata gtagtcccaa cctttccatc
     9781 ctataaaagc aatcaatatg ataacgatca accctaaaat ttttttcatg aaagatctcc
     9841 ttttttattt ttattatatt aaatattata cagataataa cggaatatta tcatcgaaac
     9901 agctaacaaa attgtcataa aaaacgagat ggttgatatt agaacttgtg tttttgttta
     9961 ggtctagaga taaagagaga caatttccaa atatatgtaa tgaatacaaa aagacgtttg
    10021 tcgcggatta ccgttacaaa cgtcttttat tgattttccg agatctcatc agtcgccatt
    10081 tggaatggtt cactccttat ctagattcgt ttaatgctcg gactgcttgt tcgattgtaa
    10141 taccaaacgc aacgttattt tcgttttgtg catcaatcgc cataaaacgg ttagaagttg
    10201 tatcaaaagc tacgcggtat tgcatatttg tttttgtaaa cgtcataaaa ttcatctcct
    10261 ttgtaatgta atttagttct tgaaagtttc ctttaaactt tcgaacttat accaagttta
    10321 gcatcgtacg ttttttgatg caattaaaaa gcatttatca ttttccttat ttattttttc
    10381 ttaaatggtt tagctatttt cttttaatcc gataagtagc ccaatcatca aggttacaaa
    10441 tactattgct tgaatataaa tcatatgctc acctctttat aaataactta gcaatataaa
    10501 gaaaaaaacg cacgaacaac ataggaatat aaacaaacgt ttttgtcaca acgtctaaga
    10561 tcgtgttaaa aaatagttat ctaaaaagca gaaagatact caaaataaaa aataaaaaaa
    10621 tgaataaaaa cgttttcaaa tacaaggtaa tttgttatta taaaataaag aaaaaacaaa
    10681 ataaaaataa agaaaagagg gaatgaaatg gtaaaagcag aagtaggaag atcttatata
    10741 tgcaaaccga tcggagtatc tcatgaacta atcggctgta ttgaacgtac atatatcaac
    10801 acggctgtcg tgtatgttga aagttatgac caacgagact atcaacttat caatgaaagc
    10861 aagtatcgca tgctcgtaaa attctgtgat attagcgcac ctactgaatt ggtttcttaa
    10921 acagtatttt tgagaattcg caagaactcc cttataatat aaataaagac agaagggagc
    10981 gagaagatat gccaaaaaga aaaagttcag ggaaaatggg aattattctt gcagtgatct
    11041 ctgcaattcc tgctatttta gctattgttc gtgcgatgaa ggaatcaaga gaaagttaag
    11101 cacacattat gagcgtcaaa caaaaaacgc atatacctgc ggtggcaggt tatgcgtttt
    11161 ttgttgtata aagacttttt tcattaacga tttttgatta gccgactccc aaaacaaaat
    11221 ttagcagttt atctgaataa gtgatttctt catctgtttg tttcacactt tcatttagta
    11281 gtcccatctc atcggttatg ataccatcca caccataaaa catcatgcga ctcatggcat
    11341 ctgaatcgtt gattgtccat acatatactt cttttccgtc ttggtgggca gaattaatga
    11401 agttacggtt gatcgtacta tattccattg tcagaaaatc agcaggcgtc acagggggcc
    11461 caacaatatt gaaaggtaag atgtagccca cataaaagtt tggttctgct tcttttaaat
    11521 ctgaaacggt ttggtacgtc aaactttgca aaatatgatg gttctctaag ataactttgc
    11581 ggtatttatg gacaaatcgt tcgacaaggt catccgaatc ttttttagag gtcttgatct
    11641 caataagtaa tttttggttt agcttatgtg ctttttccaa ataagaatca aaagaacaaa
    11701 caggggcttg cactccgttt tcagtaactg taagatttgt caattctttc aatgtaagat
    11761 cctgtggtgt tccatttacc cctgttaagt gacgaagatt tgcatcatgc atcactacga
    11821 aatgaccatc ttttgtttcc tgaacatcca tctctacata atcaggatga tagtctctgc
    11881 ttgttttttc aagtgcttct aaagtatttt gcgccccatt ttgggtactc acacctctgt
    11941 gagagacagt cactggtttt gtctgaacag ctgaagtcag ataatccata ttgtaaagac
    12001 agacgccaat accgaaaaaa actgcaaaaa gagtcaaacc agtgtttttc agcgcagaga
    12061 aacgcaagtt gggggcttgt gggataaacc acttagggat ctcaggcaag aagccttcgt
    12121 catccatgaa atcaacaatg atataaaaaa tccctacggt agacatcacg atattgaata
    12181 ataaaatccc ttgtaaaagc gtcatagcaa acacagcgct gatcaatgca tagtctggga
    12241 aaaattgttc aaccatactt tgtgccaaaa taacaacgat atatcctaaa gaagaaagga
    12301 gtaaaatcgt accgccaatc acaataaatt ggcccgtgat ggccaaaaga cgcgatttgg
    12361 tcaatgacca gctttcccga atggctgctc gaaaagaacg atctcgtaga atcatttccg
    12421 gtaaagcaaa aatcagtcga atcccaatat agccaaggaa aatataaacg agtaaaaagg
    12481 aactgacgat gatccaacga ttagcaaaaa taaaatccat aatgaaagcg gggattttta
    12541 tttttgacag tagatcagaa ttaaaactta atccgctgat cggtagaatc aataaaaaat
    12601 aagcaaggaa aaacaaaaaa gtaatgggtc tcactttctt cagctgaagt atcgtcaagt
    12661 gtaagagttg cttcaaagag attggttctt tctttttaat aaaaaaaaca ctcatcaaaa
    12721 gaaaagtaaa ttcgaaataa actaacagta aaatcgtcat caaaactacg attaacgaga
    12781 gtagaacccc aggatgttga gaaaaaattg aaggaatatt gtcataagac aaatagtcaa
    12841 ttgcccctcg gtgtaaaata aaacgggtcg tactgctcaa taagggtaaa caaataaata
    12901 aaataaagcc atgcatcagc aagacatcac ggaaataagc ttgtgttcct tttaaaaagt
    12961 cccaagcatt acctaagcta cgtttcaaat aattcatcct atcacctgct cttcacattg
    13021 tagcgcaaat ctaatgaaaa aggaaagggt gcagtgtgtt ttgcagaccc tttcccagat
    13081 ttaac
//
LOCUS       DADVXM010000067        12861 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.071, whole genome shotgun sequence.
ACCESSION   DADVXM010000067 DADVXM010000000
VERSION     DADVXM010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.071"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            301..834
                     /locus_tag="KB927_002054"
     CDS             301..834
                     /locus_tag="KB927_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBB6840962.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(1324..1848)
                     /locus_tag="KB927_002055"
     CDS             complement(1324..1848)
                     /locus_tag="KB927_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6840963.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(1841..2314)
                     /gene="tsaE"
                     /locus_tag="KB927_002056"
     CDS             complement(1841..2314)
                     /gene="tsaE"
                     /locus_tag="KB927_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBB6840964.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(2437..3417)
                     /gene="pta"
                     /locus_tag="KB927_002057"
     CDS             complement(2437..3417)
                     /gene="pta"
                     /locus_tag="KB927_002057"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBB6840965.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(3570..4250)
                     /locus_tag="KB927_002058"
     CDS             complement(3570..4250)
                     /locus_tag="KB927_002058"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBB6840966.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            4376..5245
                     /locus_tag="KB927_002059"
     CDS             4376..5245
                     /locus_tag="KB927_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6840967.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            5271..5786
                     /locus_tag="KB927_002060"
     CDS             5271..5786
                     /locus_tag="KB927_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840968.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(5833..6426)
                     /locus_tag="KB927_002061"
     CDS             complement(5833..6426)
                     /locus_tag="KB927_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6840969.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(6451..6630)
                     /locus_tag="KB927_002062"
     CDS             complement(6451..6630)
                     /locus_tag="KB927_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840970.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(6707..7216)
                     /locus_tag="KB927_002063"
     CDS             complement(6707..7216)
                     /locus_tag="KB927_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840971.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(7312..7692)
                     /locus_tag="KB927_002064"
     CDS             complement(7312..7692)
                     /locus_tag="KB927_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6840972.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            8022..8771
                     /locus_tag="KB927_002065"
     CDS             8022..8771
                     /locus_tag="KB927_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBB6840973.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(8955..10232)
                     /locus_tag="KB927_002066"
     CDS             complement(8955..10232)
                     /locus_tag="KB927_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840974.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(10311..10955)
                     /gene="pcp"
                     /locus_tag="KB927_002067"
     CDS             complement(10311..10955)
                     /gene="pcp"
                     /locus_tag="KB927_002067"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBB6840975.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(11154..12098)
                     /locus_tag="KB927_002068"
     CDS             complement(11154..12098)
                     /locus_tag="KB927_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBB6840976.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(12100..12786)
                     /locus_tag="KB927_002069"
     CDS             complement(12100..12786)
                     /locus_tag="KB927_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBB6840977.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         3713 a         2691 c         2275 g         4182 t
ORIGIN      
        1 attttttgag ctaataccga gggtcagctg attgaacacc gtttagtgga gaagttgtga
       61 aaaagtcgcc tactttcgag tcgtaagaaa tttttttgaa aatggttcct cacaactttg
      121 cataaatttg acttaatacc gagaagtcat gatccccatc taactccaaa tcacaaggaa
      181 tgagttcaaa aactagcttt tctcaacaaa tattacataa aaaattctat gttttttgtt
      241 aaatttattt gcttttttca aaagtatgtt acagtaattt cccaaggagg ttttacagaa
      301 atgaattttg ttgccatgga ttttgaaact gccaatcatc agccttatag tgcttgttct
      361 cttgcgctag tcatggtaaa aaatagccag atcgttgatg aattctatac attgatacag
      421 cctgagactc cttttttctg gcgaaatgtc caaattcacg gaatccatca agaagacgta
      481 cgcaatgcgc cgaaattccc agaagtctgg caaactatcc aaccatattt tcaaaaaaat
      541 cgtttagtcg ttgcacataa tgctgctttt gatacaaagg tcttagcggg atgcttagat
      601 tattatcatc ttgaacagcc taattatctt tctttatgta cagtgaaaag tagccgtcgc
      661 ctgtttcctg aatttccaaa tcatcgattg aacactgtgt gcgaaaattt gaacatccaa
      721 ttagatcatc accatgatgc attggaagat agtcgtgcat gtgcggaaat cctgctttat
      781 caagaaaaaa aattcgggac agatccattg aaaaaacttg tgactataaa gtaaaagaat
      841 acttatgaaa cacacaaaga ggtcgtgagc ctaccgtttc actccgagtc acaaggagca
      901 atttcaaaaa atagcttctc atgtttatta aatattgtga ctggtgaccg aggagctggc
      961 aggagaacac cgtttattgg agaggttgtg aaaaagctgt tctgcatcaa gtaataagaa
     1021 cagccaaaca aaaatagctt ctcatatttt tcatttggtt ggacttatta ccgcagatgc
     1081 aagcttttgg acaccgttta ccaagaggtt gtgaaatcag cgttttgacc tgagtattag
     1141 agaaacaaac ggcaaaatag ttcctcatat tttgccgttt tttgagctaa taccgaaggt
     1201 cagctgattg aacaccgttt attcaaaaaa aatggactgc gacacgactt ttgtcacagt
     1261 cccttcgtgt gtttttctgc cttctcaaaa ggatgacagt ttctcactct tttcctattt
     1321 cttctattca atcaaataac tcattttata tacatctaaa aattcaccta gatctgttct
     1381 tgcccctcta ggcatgaccg cttcgatttg gaagcccatt tttcggtaaa ggtgtacggc
     1441 tctttcatta cgaacttgaa cgtcaagctc caatcgaaaa agtacaccca tttccttcgc
     1501 ccaactgatg atttcttcta gcataagagt gcctagtccc attccccaat attcctgcag
     1561 aatactgata ccgacttctc ccacgtgaga caaacgaaat tgactgtctg ccttgacaga
     1621 tgctgttcca ataatcgtcc cttcatagat tgcaagcagc aataaattat tattgctttc
     1681 gtatatataa tccaactctt cttctaaggt ttctggtggt aacaggagtt ctgcttcatc
     1741 caaaactaaa aattctgtct ccttattaac ttgtcccatc atcaaaagaa tgtcttttgc
     1801 atctcctggc actgcttccc gcaagatgat cccaacttct tcactcatga ttttcagccc
     1861 atttttctag aattcgctgt ttgaaggttt cactttgctc cccgtatgag attagtttca
     1921 cataccgctt ttctaaatct gtatcacttt tttctaaaat cagttccaaa taatcctccg
     1981 gcagtgcttc ttctaataga tttccccatt caacaacgga aagcccatca ccttcaaaat
     2041 attcatctaa ccctaaatct gctccgctag ctgctacccg ataaatatcc atatgataca
     2101 acggaatccg accttgacta tattctctaa taatcgtgta tgtcggactt ttgatcattt
     2161 gcgttatccc taatccttgg gcaattcctt tcgtcaacgt tgttttaccc gcacctagat
     2221 caccagtcaa tatcagattg tcacctggca ttgcggaatg accaattgcc tctgcgaatt
     2281 gttctgtcat tgttaatcct gatagttcga tcatttttca tcttctcccg ctcttctttc
     2341 tttttgccag tatatcgcgt aatgaagttt ttttaaagaa aaaatgaact agtcaagaac
     2401 agcagctgct gtttttggct agttcgcgtg tatttgttaa tcaatcaatg tttgtgctgc
     2461 tgtgataatc gataatttat atacatcttc ttcatttgct ccacgagaca aatcagaaac
     2521 cggtttgttc aagccttgta gaattggtcc gattgcttca aagttaccga aacgctgagc
     2581 aattttatag ccgatatttc ctgactgcaa ttctggaaat acaaagactg ttgcttgacc
     2641 agctacttct gaatctggcg ctttcagttg tgcaactgaa ggaacataag aagcatcaaa
     2701 ttgcaattcg ccgtcgatca tgtattgtgg cgctagtttt ttagcgattt tagttgcttc
     2761 aactactttg tctacttctg gcgatttcgc tgagcctttt gtcgagaagc tcatcattgc
     2821 tacttttggt tcgatatcga acaattctgc tgtttttgca gaatctacgg cgatttcagc
     2881 caattcttgc gcagttggat tcacgttgat cgcacaatcc gaaaagacat atttttcttg
     2941 atctcttcca cgtaccatga tcatcgctcc gcttgtccga ctgatgccag gctttgtttt
     3001 gatgatctga agtgctgggc gaacagtgtc gccagtcgaa tggatcgctc cagagaccat
     3061 tccgtctgca atccccatat acgtaagcat cgtaccaaag taattcacat cttttaaaat
     3121 cttttctgct tgttctttgg atgcctttcc atttctacgt tcaacaaaag tatccaccat
     3181 ttcatcccac ttatcgtaat tatcagggct gatgatcgta aagctagatg ttttgattcc
     3241 tctggcatgc gctgcatttc ttatttcttc ttcgttccct actaaaatgg gttccacaag
     3301 ttcttctgct ttcaaccggg cagctgcgcc taaaatacga gcatcagtag cttccgggaa
     3361 aacgattttg atcccacggc gaacaatttt aaatcttaaa ctatcaaaca attccacaag
     3421 atgacctcca gacgttttta tatgtattat catacactat tccagaaaaa aagaacagtt
     3481 tattttatct gtatcagtca aaaatgctgg aaaaattaag tttttcacat acaaagcgaa
     3541 ctgcactata acaggaaagc gctgttttat tacactgttt caggcagttg ccaatcaatc
     3601 ggttcttctc ctaacgcaag gagcgcatca ttcgttttcg agaagggttt ggaaccaaaa
     3661 aagccacgac ttgcagataa cggactggga tgtggagatg ttatgatgat atggcgactc
     3721 ttatcgatca ttttgatttt ttcttgtgcc ggttttcccc acaagataaa cacgattggt
     3781 ttttcccgtt catttaattt ttcaatgatc gtgtctgtta atctttccca acctttcccg
     3841 cgatgagaat acgcttgccc ttcccgaacg gtaagaacgg tgttgagtaa aaggactccc
     3901 tgtttagccc atgacactag atttccatgt tgaacaggtg cgattccaag atcatcataa
     3961 agctctttat agatatttct taacgatggc gggatcttta cgccaggttg cacagaaaaa
     4021 gataagccat gagcttgatt ttctccatga taaggatctt gtcctaaaat caccacttta
     4081 acttcttcat aaggagtcaa ttccaatgct tcatagatat gatacatatc tggatggatc
     4141 ttttgggacg catattcttt ttttaaaaat tctcttagat gcagataata atcttttgaa
     4201 aattctgagg acaaaacttc ttgccaactg ttatgaatga tttctttcaa aaactccacc
     4261 tcctaataaa aagaataact cacattttct tcaatcacaa gggacaatct tcaccctcag
     4321 cacttgatta atatggtaaa ctaggaacaa gaagcagaaa ggaacgataa tcattatgat
     4381 caaattaatt gcatcagata tggacggcac attattagat gcccatatga gtgtttctcc
     4441 tgaaaatgcc gaggcgatac gttttgcaaa tgatgccggt gttgagttca tggtcgctac
     4501 tggtcgaaac tatcaagaag ctcgcgcagc tttagatgag gtaggaatcg attgtgcgat
     4561 gatcactttg aacggggcac aggtatttga taaagaagga aattcattgt ttaccgtgtc
     4621 gattccaaat aatcaagcaa tctctgtttt agatattcta gatgctaacg gtatttacta
     4681 tgaagtagca accaacgatg gtctttattc tgaaaatcaa gcgaaacgaa ttgaaagttt
     4741 tgcttccatg gtggctaccc atttacctca ccttacgtat aaaatggcga ttgccatggc
     4801 ctcagctaag ctggagttat tgcacatcac atacgtggac agtattcgtg ctattttgga
     4861 agaaaagaat ctggaagttt taaaaattat ttgttttcat acagaagggc cagctgtatt
     4921 aggtccagtt ggaaagcaga tttctctttt aggcgatcta gccgttactt cctctggtca
     4981 aaacaatatc gaagtgaacc ataaaaacgc tcaaaaagga attgctgttg cccatgtcgc
     5041 tcacgagcgt gggatttctt tagaagaagt catgacgatt ggcgataact tcaatgatgt
     5101 cagcatgctg caagtagcag gagtcagttt cgcaatggga aatgcagaaa tcgaagtaaa
     5161 agattatgcc aaatatacaa cggacacaaa ccttgaatct ggcgtaggaa aagccatatt
     5221 gcgcgcgatt gcagaagact tgtagtttta tctagaaaag agggatatag atgtcagaat
     5281 ttttcattca ggaaaagcag cttggacgtg caactcggac aattgtcaaa aacgaaaaag
     5341 gacattccct gtttttgatg gttggtcgct ggggaacaaa gggcgatgca ttgtctcttt
     5401 atgccatgaa tggcgatctc gttgctcaca tcaagcagat aagcctgaca ttcggtacgc
     5461 gttttgagct gtataaagag ttcgaaaagg tgggaaccat gcagaaaata ttcaattggc
     5521 ccggtgactt ttattatatt cgtagacttc actggacagt ccaaggtgat atctataatc
     5581 atcaatatca aatccatcat ttcaatcagc aaatcatgaa aatggataaa gcaacacttt
     5641 tttcaggaga ttactatgta ttggatgtct caaatgatga agatgctcca gtttgtattt
     5701 gtattgctgc ggttttagat tactggctct accgtaaaga caaaagtcgc gataagcctg
     5761 tttcttaccg acttaactta agttaaaaag atgtacctga aatgcggaaa tacgcatttc
     5821 aggtacatct ttttagatat tcttttgcat atgatcataa agatgaccac tgatcatccg
     5881 ctgaccgaca actttgaagt catggcgttc gtataatttt ttagcctttg gatttttttc
     5941 atccacactt agaccgatga cggagcgatt agctttcttc gccaatttag gtaatgcttc
     6001 taataatcgc gaaccgatgc cttgtcctct aaaatcttct gatacactga tagagtccaa
     6061 ataccattcg ttgggaaacg tttctttatc aatgaacaaa cgtgtagacg catctagctg
     6121 atatttctct aagataggta ccagtggctg atcgatgatt gattcttctt catctgtata
     6181 accgtaagca actcctgcaa ctttaccgtc tatttcttct acgatacctc gtgaataact
     6241 gtaacgataa tttggatcag tgattgcttc ttctaaaatc tctaaagtct tttgttcccc
     6301 tgtctgcttc aaaaatggca gttccatatc ttttagaatc actaagatca atggggcgat
     6361 ttctggagca tcttcttttc tcgcaaaacg aatcatagtt tcctctcctt ttctccattc
     6421 taacatgcag aaaaagaaat cgcaaaatcg ttattttaaa aaatcttcaa tcttttcagt
     6481 aatgaaataa ccatgagtaa cgattcttgc cgcttcagtt cggcaataag ggcagacgac
     6541 tggcatttct ttatcattat gttcgactac attattgact tcttcgtatg caaatttttt
     6601 tccgcaatta gggcatttca ttttttccat gttatctcaa cttcctttca tctttactct
     6661 cttagcttac tcttatattg taaaaaagag aagcaatatc cttcttctat gcagatatcc
     6721 atacctgacg gtcctgttct ccatctatta atcggacttt ataataagga cgttcatctt
     6781 tgactagaag tgtccactct ttcacttttg cttttttccc gtagtagctg actgcttcct
     6841 tcatcgctgc ttgcggttgt ttgaactctt ccgttttttc tatatcaaaa agatgttctg
     6901 cggccttttc cgtgtcattt cgtacggttg ttttcccagt ggatggattg actgctatga
     6961 cttgtccttc acaaaaaaac tggtattcat atgttgcatt cgtaggattc tccaaatctt
     7021 tttcaactgc aaaatgaata gcagatatgt tatgttcttt tgtttcgttt tttacgattg
     7081 ctgctgcttt tttcaatgag atccgatatt cctggtcact aatatcatcc atgtgaaaag
     7141 cggcattgag cagtcccgtc ataccggtaa tccctattac gatgagggca gcaacaccaa
     7201 acatcatttt tttcattctt cattctcctg tttctttttt ttaaagaata tcaagaaatg
     7261 aacgaatgaa aaatcgaatg aaacgaaaaa aaagtgacaa ttttgttatc tttattcgtg
     7321 cagttctaat ggcaatccgt ctggatcaaa gaaaaacgtc attttttttc ctgtaaaggt
     7381 atcttctcta atcggttctg attcgatccc taaggactgc aattctgcaa ttgtttcttc
     7441 aatatcgtct actttgaaag caagatgacg caagccacaa gcttctggat agtttggtcg
     7501 ttgtggcgca ttagcaattc caaaaatctc caattcagca cttcctagtt tcagatctaa
     7561 tttatagtca tctcgttctt tgcggtaatt ttctctgatt acttcaaatc ctaatttatt
     7621 aacataaaaa tcacgtgatt tctgataatc tgaaacaatg atggctatat gatggatcgt
     7681 tgtaaggttc atatgagcac tcctattctt cgtttaagct cggatctata ttaatctcca
     7741 gttccattgt aaatgtgtca gattgaaaaa aatagctgtt tttccttttt ataagaaaaa
     7801 aggcaaaaaa aacagaaagt aggtcctcca agacactctt cctgttccca atataataaa
     7861 tgaaagtaag aaattatatt ttcaagaaaa caaacagaaa attatcataa cacaaattat
     7921 ttataattga aagactagtt ttttttcaag aaaagcatac aatagattgt gttagtaaat
     7981 acagaacaca ctacatttag tgtcttaagg agtcctcata catgaagtca tattttcagt
     8041 ttttagctca tcagctaaaa ggctggccgc aacaaaatta ttatcttttc tttttcagtc
     8101 ttggctgcca ggtcatgact cttgtcaata gtcccatcac ttggctgtcc gttattacat
     8161 ttatcggtac cacgcttggt gtattgtgta ttttatccat caatgcggca aaatcagtca
     8221 acggtatttt aggtattttg tctgcgattt gttttattat cgttgggttt tcagcaaaga
     8281 actatttaag tatcggtgaa cagattgctt atatgatcac attggatatc cccgtattgt
     8341 taagtaaaga atggaatcat aatatggctt caaaaatccg aaaattcact ggaaaaagct
     8401 ggtttatcgc aatcatcagt actttccttg tctatcttgt ttcaggattc ctgattggtc
     8461 gttatacaga tgatcctcgg ccgtgggtag atgccattgc tttttctatt agcttgactg
     8521 ctggtatcat cagtttcttg cgttacaaca accaatatta ctggtggtta gcttcagggc
     8581 ttgctcaaat ggtcctttgg tatatttcat ttacgcatgg atctgcaagt ttggcgatgt
     8641 tcgtgaacag ctctgtttac ttgctgaatg atgtccttgc atttaccgtt tcaccttggt
     8701 ataaccaaaa agaacgtgaa cgtatgcaaa aaatggaaga agaatactac aacgcacaac
     8761 aacacgcata aaaaaactga gcgtgggaca aaagtaaaga acacttttgt ctcacgctct
     8821 aaacacgtat aaacggcgga atcagaagca actccttcgg aaataagctg aaattcacaa
     8881 aaatttgaaa agcaattttc gtgaatttct tcttatttct tggagttaaa cgcttctgtc
     8941 ccagcctcta ttttttatag taattccttc agatactttc ttgcctcatc attgaaacgc
     9001 agtgattctt ctaacttctg ataatattcc aacgcttgtt tctgagcttc agtaaaacga
     9061 taatgttttc ctttccattt gtcgattgtc tcttgcacat ttccagattg gatatctttc
     9121 actactagtt gccatttttc ttttgagact gtacggtctt tcttatcagc agattgtata
     9181 gcttctcgtt ctttacgcaa tacttttaaa aaaccatttc tgactatccg aggaatgctg
     9241 tcgaagaacc cttctgtaaa accatagcga caatattgct tccaaataaa tagatagatt
     9301 tttggttgga tgaatcgttg gtttttcgca aaatattcca tctgagcagt gacttctggt
     9361 gttcgttgac gttttgtctt tctcaacacg gaaataaatg tttcaaaata agcattagga
     9421 tgtactggca cttcttcata tacgatggat tgccaatctt tacgtaaaaa tgcgcgatag
     9481 ttgatcaaga attcttctac atcctttact aattcttctg caaagtcgtc aaatagttct
     9541 ttttttatct gtcgcttttt tgactgccca ttgatgtgtt cacttatttt cttgatttca
     9601 ttttccaatg cttgataatc cgctatgtaa atcggcattt ctacttggcg aaattctgcg
     9661 agccgctgag ctaattttat atccggtaaa tatggctgtt tcatccgacg attttggtac
     9721 aagacaaaac agtatttttg ccatagtcct tcaggaaaat cgatattctt ctgcttaagc
     9781 cataataatt cgtctaaggc cagatcaact tttgtcattc cctgatggat cgaagctgcc
     9841 actgtcggag agacatgcag gtgatcggca aagtggttga tgcctagttt taggatcttt
     9901 ccggtttttg gcgatttaac gatgtattgc acttttaatt ctctaccaca ctcacaatac
     9961 aatttttgct ggcttcgttt tgttcgaaaa aacggattga tcttgaagtc agaaaacacc
    10021 caatctgttg cagctaaata atgttcttcc ataaaacgag agctgattag atatcggcgg
    10081 tgcttatcga ctagttcccg ctgttttttc gttaattttg catagatctc ccaacgttga
    10141 ctgcttgtgt attgtttaga aattttgatg ggatagcttt tgctgatttc ttttggaaac
    10201 cattcttcaa agacggattg ccattcttcc acggctgttt ctttcctttc taattacaaa
    10261 aagctggcta ctaacataac gttagcaacc agccagtgtt tcttgctaaa ttagtgagtt
    10321 gttccggcat ttccggaaat atcttcttta ttttctactg ctgcttcaac tgcataagtc
    10381 aaagaagaag caatgtcttc taaagacata gaaggcgtac ccactggacg atcgatcact
    10441 tgatcgggtg agaatggcac gtggatgaac ccacctcgaa ttgccgggaa ttgtgtttcg
    10501 atcaaatgaa gcaaacgata catgatatca ttgcagacaa atgttcctgc tgtataagag
    10561 atgtacgctg gtagaccatg atcttgtaca ttttttgtca ttgctttgat tggcaatgag
    10621 gtaaagtaag cggctggacc gttttcttct aaagccgtat cgaatggctg atttccttca
    10681 ttatcaggga ttcttgcttc tgctagattg attgcgacac gttcgaacga gactgctgac
    10741 cgcccacctg cttgtccgac acagatcacg acatctggtt ggtgctgttg gatggcttct
    10801 ttgactactt gactgctttt ttcgaatacg gtcggtactt ccactttgat gatttcagca
    10861 ccgctgattt catctggcat tttttttact gcttcatagg ctggattcac tttgtcccca
    10921 ccaaatggat caaaacctgt tactagtact ttcatctgtt gttcctccgt ccgattgatt
    10981 taacatatgg ttatctttta tcataccatt ttccttgaac agcgtaaata aaggaaacaa
    11041 tagtttaaat aacataacag atcaaactta atatattctt ataaaaaaat agtgttccac
    11101 tacaatgtta gaagaggttg cgacaattat tctgtcacaa cccctctctt ctattattta
    11161 aatagaatca tataagcaat ttggaaaact agcataaata acgcaataaa caactggttt
    11221 ttgatcactc cgtatttgtc tttcatctcc agcatcgcta caggcacgat attgaagtta
    11281 gcagccatcg gtgtcagcag ggtcccacaa aaaccgcaag tcaatgcaac cattcctatt
    11341 aacgctggat tcgctccatg actaaatacg aatggtgcac cgatcccaac cgtcatcacg
    11401 gtgatggccg caaatgcatt ccccatgatt accgtaaata tcaccatgcc aagagcgtaa
    11461 atgatgatgc cgatgttcac atttccttct ggaacgatcg tacctactgc attggaaatc
    11521 actgtcccaa ctccagcgct tgtaaatacc gcacctagag aagctaaaag cattggcaac
    11581 atgcttaacg gccctactgt gcccagcata tctgctgcat catctaaaaa tgtacttggt
    11641 cgattatctc gagaaaagaa catcaagatt agcatggctg caaaaacacc gacgcccacg
    11701 ccgactaaag cacctaaatt ggtaaataga gcaaacaaga tcgcaaagac accgatactc
    11761 aaagctggaa taaaaatttt cattcctagt ttgtctgaca ttttttccat atattctttt
    11821 gatggaagcc ggctttctcc tttgctgact ttcttagcaa ttgctggtat ggtcatcgca
    11881 aagatcaagc caccgttcac gattgccgga agccatcttc ctcctgcaat aactacccct
    11941 aagaccgtcc agaaaaaggc tgacccataa cgatgaggat tggttttatc tgttaaattt
    12001 cttactccag tgtaaatcaa tacgagtccc atcacgatat aaaggatctc cagtaattta
    12061 tcgcctaata aaatatcagg atttgtaaaa aagtccatct tattgcccct ttcctggata
    12121 atatttcttc gctaatttct tttctttaag atagaagtag acacttgcca caactaaagc
    12181 cgtgatagcc actggaactt ccactaaagc aagctgtccc aatgttacgt catatcctag
    12241 atctttcagt gttgattgga ctagcaacgc ccctgctcct ccgatgaata gtacttggcc
    12301 aaagaaccag cagacatttt ccatagctga agccatacct tttagttctt cttcatgctt
    12361 aggatggact tctaaccctt ttgattcgat ggtccccaat gccatcggta aaatgattgg
    12421 acgaacaaat ccagcaactc caccaaaact cacgttaaaa gccgcaaaga tcattcgaaa
    12481 gatcccataa atatctacaa tcataccagc agatactttc ttgaatcgct tgatcaagga
    12541 agccgctgat tctttcagac catttctttc aagcgttcct gttgccaaca taatgatgat
    12601 aaaaatcgcc atcccgcgat tgtttacaaa acttgtacct aaaagttcta acattccttg
    12661 aatgccaaga ccgccagtca aagctgtaac aactaaagca accattacga tcaatatcga
    12721 gtctaattta aatgcaaacc cgagaataac aatcaagacg cctaaaaggc taagataatt
    12781 ttccatatat tttcctccat aaaatgacaa tattttttta attataaagc aaaacacata
    12841 aaaaatatag ttgttttctc a
//
LOCUS       DADVXM010000068        12804 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.072, whole genome shotgun sequence.
ACCESSION   DADVXM010000068 DADVXM010000000
VERSION     DADVXM010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.072"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(247..1158)
                     /gene="vanY"
                     /locus_tag="KB927_002070"
     CDS             complement(247..1158)
                     /gene="vanY"
                     /locus_tag="KB927_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBB6840978.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYETWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(1586..2194)
                     /locus_tag="KB927_002071"
     CDS             complement(1586..2194)
                     /locus_tag="KB927_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBB6840979.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(2200..3231)
                     /gene="vanA"
                     /locus_tag="KB927_002072"
     CDS             complement(2200..3231)
                     /gene="vanA"
                     /locus_tag="KB927_002072"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBB6840980.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(3224..4192)
                     /locus_tag="KB927_002073"
     CDS             complement(3224..4192)
                     /locus_tag="KB927_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBB6840981.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            complement(4407..5561)
                     /locus_tag="KB927_002074"
     CDS             complement(4407..5561)
                     /locus_tag="KB927_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBB6840982.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            complement(5539..6234)
                     /gene="vanR"
                     /locus_tag="KB927_002075"
     CDS             complement(5539..6234)
                     /gene="vanR"
                     /locus_tag="KB927_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBB6840983.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            complement(6448..7023)
                     /locus_tag="KB927_002076"
     CDS             complement(6448..7023)
                     /locus_tag="KB927_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6840984.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            7169..10135
                     /locus_tag="KB927_002077"
     CDS             7169..10135
                     /locus_tag="KB927_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HBB6840985.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            10276..10881
                     /locus_tag="KB927_002078"
                     /pseudo
     CDS             10276..10881
                     /locus_tag="KB927_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(10926..11093)
                     /locus_tag="KB927_002079"
     CDS             complement(10926..11093)
                     /locus_tag="KB927_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6840986.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(11127..11426)
                     /locus_tag="KB927_002080"
     CDS             complement(11127..11426)
                     /locus_tag="KB927_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBB6840987.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            complement(11467..12084)
                     /locus_tag="KB927_002081"
     CDS             complement(11467..12084)
                     /locus_tag="KB927_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6840988.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            complement(12409..12804)
                     /locus_tag="KB927_002082"
     CDS             complement(12409..12804)
                     /locus_tag="KB927_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6840989.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
BASE COUNT         3857 a         2600 c         2262 g         4085 t
ORIGIN      
        1 ctgataaaat attgtattgt aatttgaata acactaacca gattagtgtc actaaatata
       61 aagctagcaa tcctctagat aatatttttc ccaatataat ttcctctaat tcttttgttt
      121 aagttgtatc attagtatag caatgtccta gttaacgtgg gttttaaatt aaaaagctaa
      181 cgttacccca aaagtgctag tacaataatg ctgttcatta atttcgttgg tttcattccg
      241 ccatccttac ctccttgaat tagtatgtgt tgatccggga aacactgtca caattacacc
      301 gtctatattg tttcctgata tctcataacg aagattagtc ggcacatgaa tggtggtatt
      361 tttagtaaca ggataataaa agatctcata tttttcccca tttacactaa cagaaatggt
      421 tttttcttct tttaggtaat ccatatattc ctcgagaacg aaattctttt ctttcataat
      481 cgcactatgt ggtaaaccaa catagcgaat atgccatgtt tcatattgaa ttcctgttaa
      541 ctctgttttg tcctctggat aacgtaaaat gaacccgtat ttccaagcat tttcttctat
      601 ccactttcct tcaggggctc gttccatttt cgtcaagctt gatcctacat ctagtgataa
      661 acctgaatta tgctcactat aacctgctgg taaggcatac tcagccccca tttcttggta
      721 aagcacactt tgctcatcaa agtctcgata gccactatta ataataaaat gactaacgcc
      781 accctttaca gcatcattga ccatctctga aaatttttgt gctatttctt ttgacatata
      841 aatattacta tcaagcaacc cgtatccatt tattaattcg tcatgtttag ataaattcac
      901 gatatctgac ttcacacttt cttggcgaac aggatattta ctattgatta atagcagatt
      961 tccttgataa acctgttctt ctgtaattgt tttctcttgg gtattttcag aagtcccact
     1021 attttctaaa tgttctttgg gattttgatc ataattttga aattcgactt tttcctgaga
     1081 aaacagtgct tcattaacgt agtcataacc taagtatatt aagaataaca ataacaataa
     1141 aaaaaacaac ttcttcattt tcagtctcct ccttaactat atagttggaa gtatgaaata
     1201 tttctagaat cttcccctta aacggcacaa tctcgtttga gattgtgccg ttttgccccg
     1261 taaattacag tcaattattt cgccctactg gatttactat tatcaccaat gtagatgaat
     1321 tttcataagt gatacccatg ctgaatttaa cgaggctgaa ctgcctgttg acaatgggcg
     1381 gtgtgaaata ccacccctct atgcgatcag tcttattatc aggctatctt gccgcagcgc
     1441 acgcagataa tgaccgcaat atcgctctgc cttacatctt caatactatc tactatatat
     1501 aaattcccta agaaccagtt acatacgtcg ggtttcctgc cgaaagagtt agcttatata
     1561 gtttgtccgt gcaacggtta aaagtttatt taacggggaa atcaaaatag ctattggggt
     1621 atggttcgtc tcttaataca tagtgccacc attcgaggct atatgcttca aacccactgt
     1681 tttccatgat ggagcgcaaa cgtctgcgat tttgcgcttc attgcatgat attccatttg
     1741 ccgcatgatg agagcgttca tccataaaat caaatcggct ccccattggt acaagctcac
     1801 ccgtgtctaa tcgataaagc gtaagatcaa tggcactgcc gcggctatgg cttgattttg
     1861 aagccacgta tccttttgaa atcatctcag ttcggtcaat attgggataa taactttcct
     1921 ttgtcaggtt attttccggc tgtgcagccc attgcataaa acagtttaca gcacgcttag
     1981 gacggtaacc gtcccataga agcaatccgt acccttgggt agcagccagt tcttttgcct
     2041 tcaaaagcga ttcagccaac tcgtatgtcc ctacaatgcg atttacttca taaccgtcaa
     2101 ccggttttcc ggtgaaatta tcccaagtgg catatttagc gtcccaacga acaccgtgta
     2161 ctatttcatc taaaaaagta aatcctattt ccatgcttat caccccttta acgctaatac
     2221 gatcaagcgg tcaatcagtt cgggaagtgc aatacctgca gcggccatca tacggggata
     2281 acgactgtat gacgtgaaac cgggcagagt attgacttcg ttcagtacaa tgcggccgtt
     2341 atcttgtaaa aacatatcca cacgggctag acctctacag ccgagcgctt tatatatttt
     2401 ttttgccgtt tcctgtatcc gtcctcgctc ctctgctgaa aggtctgcgg gaacggttat
     2461 aactgcgttt tcagagcctt tttccggctc gacttcctga tgaatacgaa agattccgta
     2521 ctgcagcctg atttggtcca cctcgccaac aactaacgcg gcactgtttc ccaataccgc
     2581 acaaccgacc tcacagcccg aaacagcctg ctcaattaag attttgctgt catattgtct
     2641 tgccgattca attgcgtagt ccaattcgtc cgcgctattg acttttttca caccgaagga
     2701 tgagcctgaa cgcgccggct taacaaaaac aggataggta aacgtagctg ccaccggcct
     2761 atcatcttta ttaataaccc aaaaggcggg agtagctatc ccagcatttt tcgcaacgat
     2821 gtatgtcaac gatttgtcca tacaaattgc tgagctttga atatcgcagc ctacaaaagg
     2881 gataccggac aattcaaaca gaccttgtat ggatccatct tcacctgact tgccatgcaa
     2941 agctgaaaat gctacatcaa catggttgat ttcatattca tggttctttt taacaagtaa
     3001 tccgtgcatt tttttatccg gcgagagtac agctgaatag caattgtcgt tttcccattc
     3061 cgcgcaaggt ttttcgcaca ttttccatac accagatttc gtaattccaa tgtataacgg
     3121 ctcgtatttt tctttattaa tgttagcggc tatctctatt gcagatttta ccgatacgtc
     3181 atgctcctct gagcaacccc caaacagtat tgcaactttt attctattca tgctcctgtc
     3241 tcctttcaaa atccaaacag tttttaatgg ttttttcaac ggtatcacgc aacgcttgct
     3301 cggtataata ggccgtatgc ggtgtgatta tcacgttagg cattctttga agtttaagta
     3361 aaaattgatt atcaattggt ttttgggtgc aatcagagta gaaaaactct tcctctcctt
     3421 ccaatacatc caatgcggca ccgcccagtt tcccgttttc taatgcttta accaactcat
     3481 aggtatctac aagtggaccg cgcccagtat tgataagaaa tgctccttgc ttcattctct
     3541 gtatttgttc gtggctgata atatagtgcg tatccgtatt gagcggcaca tgaagcgtaa
     3601 cgatatcgct attttgcagc aactcatcaa acggtacata gtttacctct atacttcggc
     3661 tgcgactata agccaacact ttacatccaa atcctcgcag ccgctcaata accgctttgc
     3721 ctatctggcc cgttcccacc acaccaactg tcatgtcgct gagtaccttg ccacggtcgc
     3781 tgtccaacct gaaatcatgt ttttccacag agcgcacaat cgattttacg ttgcgtactg
     3841 ccataagaat tagcatcata gtataatcgg caacgctatc cggcgagtac gccacattgt
     3901 cgacagtgat gcccattctc ttagcagcag ttgtatctat atgattgcag ccgatgcttc
     3961 gggtagaaat atatttcaca ccggctctct tcagcgcaag aagaatagag gcggaaatct
     4021 ctgatttatg tcccacactg atacattgat tgaaaggcgc ggatttggcg ttggattccg
     4081 acacgttggc gttaattatc gttgccataa cgccaaagcg aggcgaaaga gcatggaatg
     4141 catctgcctc atcctgctca catccataaa cagtaatgcc gatgttattc ataattaaga
     4201 ccaacccttt ctgtgaaagg caccaaataa aacggggatg ccaatggtaa tcttgtcaaa
     4261 tctttctctg aagaacgaaa acggctcgtt cttacggtat taagtctacc gtgtaagaac
     4321 gagccgtttc ttaatattaa attgttaatt tcctaagaaa aagtaaagat aaccttgaga
     4381 ttttcctaaa aaattatata catctcttag gacctccttt tatcaaccaa gtctggcatc
     4441 gctggaagct ctaccctaaa cgtcgtatag ttatcattgc tttccgcgta aatctgccct
     4501 ccatgctgaa caataatttc ttttgcaatc gccaatccaa gtcccgcgcc acccgtatcg
     4561 gaagaacgag cattgtccag cctatagaac ttttcaaata tggcagctag cttatctttt
     4621 gggatgcttc cagtgttctt gaattcgatt gacaccacat ccccggagag gcccgcggta
     4681 atgtcaatga tgctgttatc ctcactgtat gcagcggcgt ttttcaaaat gttgttaaag
     4741 actctcgcga gtttatcagg gtcgccggac acggtcagat cctcgggggc gtgaataacc
     4801 gcctgttttc catgtgcgga aagctgagga taaaattcat cggtcatctg caccagcata
     4861 tagtataggt ctatgtgcgt ttttgttagc gttatcgttt gtaggttata ccgtgtaatc
     4921 tcaaaaaact cgtcgattag ctgttcgagt cgatacgctt tgtccaacgt gatatgcaca
     4981 tactttgcct tttgatctac cggcatgtct ggagcctcgt caagcaggct caaataaccg
     5041 ataatggatg taaggggcgt tttaatatcg tgcgccaagt acataacaac gtcatttttt
     5101 ctttgttcgg ccagctttgc atcctgctct cgcttttcca gagtccgttt taatgtgttg
     5161 agcttttgtt ccataacatc catttccgca gaaagctcaa tttgtttatc ttcgttctga
     5221 ataagtacat caatgccggt atttatctcg tcaaagtatt ttgcgaattt tgaaagcatg
     5281 acgcgacata gaataagaat actaatgaca atcgccacat aaataaagat atctatattg
     5341 ttccgtatgg aatattgata taatttcatc gcgtccaggt gatttaagtc atatttgttt
     5401 tccaaaatac ttaagatcca atccccaagt ttccctcgga tcattgaacg aatatacaac
     5461 acgaatacaa ttgctaccac aacaattgca acgatataca tgtaaagttt tcgttctagt
     5521 ttggaatagt cgtttttttt atttttcaat tttataacca accccccata ccgtttttat
     5581 atatttcgga ttatcaatgg tgtcgttcat tttttcgcgc aaatgccgga tatgcacggt
     5641 gatggtgttg ttgctcttgc tgaaatattc gtcgccccat atctcatgaa atagcagctc
     5701 ggagctaacc acattcccct tgttttcaca gaggattcgc agtattgaaa actcggtggg
     5761 agtaagggat aactgcttct cgttcagata acactcatgg gtgttaacat taatgacaag
     5821 gccggagtgg acgataacat tttcgttctg ctcctttact ccactgaatt ttttgtatcg
     5881 gcgcaactgg gcctttaccc gagcaattaa ctccagtggg cgaaagggct tcgttatata
     5941 atcatccgcg ccgattgtta accctgtaat tttatctacc tctgtatctt tcccggtcag
     6001 catgataatc ggataggtgt gcttgtccct tattttttga cagatagtaa ggccgcttgt
     6061 gccgggaagc atgatgtcca atatggcaag gtcaatctca gacttgtcta tacattccaa
     6121 tgcttctttg gcggtatagt atttgaaaac cgtataattc tcgtttttta agtataattc
     6181 aaccaaatcg gcaatttcat gttcatcatc cacaataagt attttatcgc tcatagttat
     6241 caccctttca cataagtttg cccttaataa tttatcagat tatagggccg aatttataag
     6301 catttacata ataaatgact aagaatttct taagatgatg attctttttt tatcaaaggg
     6361 cttttcggca tcgctaggag gctgttaata ttttatagtt tccttttctt ctttaaaaat
     6421 attgcccatt agcggaatac agaatggcta attattcact tctgataatt tcctgtataa
     6481 tgaagcccta gatacattag taatttcaca aatttgattt acagtcatat ttccttcttt
     6541 atatagcttt accgcataat tcattcctgc gtgattttta tgatacttct ttaatcgacc
     6601 tttaaacttt ccttctttct tagccaattc aatcccttca cgttgtctca tccgaataag
     6661 atctcgctct aattggttaa caccagccat tacagtaatt aagaattggc tgtatggatt
     6721 atcttctgat aaatcaagcc atgtatcttt tagtgatttt aaacttgcct ttttatctcg
     6781 tatgttatcg attaattcaa atagatcttg tgtactacga gtgattcgag ttaagtctgt
     6841 aacataaatg atgtcatctt cctgtaaatc gtctaacact ttttgaagtt gctcgcgatc
     6901 ctttgttgct cctgaaactt tctcttcata tataatatcc attccgatct cgttcaactg
     6961 ctgaaattgt cttgaaggat tctggttagt cgaactgaca cgaatataac cgattttccg
     7021 caaaatatca cctcattttt gagacaagtc ttatgagacg ctcttaacta tgattttatc
     7081 agtctactac atttgtatca atagagtaca ctctattgat atataattga actaataaat
     7141 tgaaaataca gaaatggaat gatactgaat gaaaattgcg agaggtagag aattgcttac
     7201 accggaacag agacaggctt ttatgcaaat ccctgaagat gaatggatac tggggaccta
     7261 cttcactttt tccaaacggg atttagaaat agttaataag cgaaggaggg aagaaaaccg
     7321 tttaggattt gctgttcaat tagctgttct tcggtatccc ggttggccat acactcatat
     7381 caaaagcatc ccagattcgg tcatacaata tatatcgaaa cagattggtg ttagtccatc
     7441 ctcgcttgat cattatcctc aaagggaaaa tacactttgg gatcatttga aagaaattcg
     7501 aagtgaatac gactttgtaa cttttaccct gagtgaatat cgaatgacat ttaagtacct
     7561 tcatcaatta gctttggaaa atggtgatgc cattcatcta ctgcatgaat gcatagattt
     7621 tctaagaaaa aacaaaatta tactgcctgc tatcactaca cttgaaagaa tggtgtggga
     7681 agcaagggca atggctgaaa agaagctatt taatacggtt agtaaatctc taacaaatga
     7741 gcaaaaagaa aagcttgaag ggattattac ctcgcagcat ccatccgaat ccaataaaac
     7801 gatattgggt tggttaaaag agccaccggg tcatccttca cccgaaactt ttctaaaaat
     7861 aatagaacga ctcgaataca tacgaggaat ggatttagaa acagtgcaaa ttagtcattt
     7921 gcaccgtaac cgcctgttgc agctgtctcg cttaggctca agatacgagc cgtatgcatt
     7981 ccgtgacttt caagaaaata aacgttattc gatattaacc atctatttat tacaacttac
     8041 tcaggagcta acggataaag cgtttgaaat tcatgatagg caaatactta gtttgttatc
     8101 aaaaggtcgt aaggctcaag aggaaatcca gaaacaaaac ggtaaaaagc taaatgagaa
     8161 agttatacac tttacgaaca tcggacaagc attaattaaa gcaagagagg aaaaattaga
     8221 cgtttttaag gttttagaat cggttattga atggaatacc tttgtctctt cagtagaaga
     8281 ggctcaggaa cttgcacgtc ctgccgacta tgattattta gacttactgc aaaaacggtt
     8341 ttattcacta agaaaatata cgccaacgct attaagagta ttggaatttc attctacaaa
     8401 ggcaaatgag ccacttttac aagctgttga gattatccga ggaatgaacg aatctggaaa
     8461 gcgaaaagtg cctgatgact cacctgtgga ttttatttca aaacgatgga aaagacattt
     8521 atacgaggat gatggtacaa caattaatcg tcattactat gaaatggctg ttttaacaga
     8581 acttcgggag catgttcggg caggagatgt ttccattgtt ggcagcagac aatataggga
     8641 ttttgaggaa tatttgtttt cggaagatac atggaatcaa tcgaagggga atacgagatt
     8701 atcagttagt ttatcattcg aagattatat aacggagaga accagcagct ttaatgaaag
     8761 gttaaagtgg ttagctgcca attccaataa gttagatggg gtttctcttg aaaaaggaaa
     8821 gctatcactt gcacgcttag aaaaagatgt tccagaagaa gcaaaaaaat ttagtgcaag
     8881 cctttatcag atgctaccaa gaataaaatt aactgattta ctcatggatg tggcccatat
     8941 aacaggattt catgagcaat tcactcatgc ttccaataat cgaaaaccag ataaggaaga
     9001 aacaatcatt atcatggctg cccttttagg aatgggaatg aatattggct tgagcaagat
     9061 ggccgaagcc acacccggac ttacatataa gcaactagcc aatgtatctc aatggcgcat
     9121 gtatgaagat gccatgaata aagcccaagc catattagta aactttcatc ataaattaca
     9181 attgcctttc tattggggcg acggtacaac atcttcgtca gatggtatga gaatgcagct
     9241 aggtgtttca tcactacatg cagatgcaaa tccacattat ggaactggaa aaggagccac
     9301 catctaccga tttacaagtg atcaattctc ttcttactac acaaagatta ttcatactaa
     9361 ttcaagagat gcgattcatg ttttggatgg tttgttacat catgagacgg atctaaacat
     9421 agaggaacat tatacagaca ctgccggtta cactgaccaa atattcggac tgactcattt
     9481 attaggattt aaatttgccc caagaataag ggatttatcg gactcaaaat tatttacgat
     9541 agataaagca agtgagtatc caaaactaga agccatttta cgtggacaaa taaatacaaa
     9601 ggtcattaaa gaaaattatg aggatgtttt gcgattagct cattctataa gggagggaac
     9661 agtttcagca tcccttatta tggggaagct aggttcctat tcaagacaaa acagcttagc
     9721 tacagcctta cgtgagatgg gccgaataga aaaaacgatc tttattttga attatatatc
     9781 ggatgaatca ttaagaagaa aaatacaaag aggattgaat aaaggagaag ccatgaatgg
     9841 attggcaaga gctattttct tcggaaaaca aggtgagctt agagaacgca ccatacagca
     9901 tcaattgcaa agagccagtg ctttaaacat aattatcaat gctataagta tttggaatac
     9961 tctccaccta acaacagcag ttgaatataa aaaacggaca ggtagcttta atgaagattt
    10021 gttacaccat atgtcgccct taggttggga acatattaat ttactaggag aataccattt
    10081 taactcagag aaagtagtct cattaaattc tttaagacca ctaaaacttt cttaacgttg
    10141 ttaaaaacga gggattcgtc aggaaaatag gcttagcgtt gtaaatccgc attttcctga
    10201 cgctacccct gatagcagta aaactacaag taaattttac atgtaaatta tatcactttt
    10261 aaaaaggagt tttttatggg aaaaattggc tatattcgag tatcttcaca agatcaaaat
    10321 ttggatcgac aattggcaat gatggaagga cttaacattg ataaattatt ccaagaaaaa
    10381 gccagtggta aagatactga gcgtcctgag tttcaaaaat tactaaatta tatccgtgaa
    10441 ggtgattgcg tcatcgttac atcactagat cgtttaggaa gagattatga agatataaaa
    10501 aatacagttg cttttatgaa acagaaaaaa gtagcgttaa aaatattaga tgcacagttt
    10561 ttagatttta atactggaaa tgaactcctg gataccgcta tgttcgatat gtttttatca
    10621 ctgctaagtt atattgcaca aaacgagcgt gagaaaattc gtgaacgtca gcggtaagga
    10681 gtattattgg ctcaaaaagc cggccgatat aagggacgac caatcgagta ttctattaac
    10741 tcaacagatc cgcaaaaacg cttagttttt aaaaccgtgg tggacatgtt aaagcaaggc
    10801 attccagttg cagagattgc aaaagaaaac gggatctctc gaccaactat ttataaaata
    10861 aagaaagcga atgatttgta gaaatatact acattcattc gcttttctac cgcactattt
    10921 cgtttctatg ttccatgtac cccgtatcgg cgatggcatt taggacagta aaagtaattt
    10981 ttttgataaa cactttttgc taattcccca cagtcacact ccacgtgaaa agcaatattt
    11041 cgattaaaac tagttatttc aatgccccaa cgatcataag attttcgctt cataaaaatt
    11101 ttcctccttg taaattttac taacgattat aaataccgtt gccattcttt caactgttga
    11161 ctaattaacg cataaaattc gacttctgat aaaatggtaa tctcatgacc taacgcaatc
    11221 aagtcccgcg cggtttgttc cttttttgta tagagagaat catcaaacaa cgacttagaa
    11281 tactgaccac aaaccaggaa atttgttttt gaagtaacac ttgattgaca atggccgttt
    11341 aaagagtgaa ccaaaccgat ggcttgggtt cgtgtcattt gctgcagcgt tccagtaaaa
    11401 acgacccttt gattcgttaa gtccattttc aaactctccc ttcccgtcta atagctgtta
    11461 tatctatcaa gaaaagtggt gcaaggtatg ttcatattct ttcacccgtc gataaaaggt
    11521 atttcgtttc atgcccaatt gatccatagc atagactgca gttatctttc ctgctttcca
    11581 gtcagaatag atcgcaggaa attcaggagg taaagcaatt ttctttctgc cgaattttac
    11641 acccttttgt ttcgcagctt ctacgccttc tctttgccgg ctattaattc gtttccgctc
    11701 gtcttcggcc atatagctga gtaattgcag aattaagtca gagataagcg tctctaaccc
    11761 atctagttgc ttgtaactag cagtatctaa cagaggcatg tctaacacag aaatatcaat
    11821 ctgcttttcc ttagttaatt ctcgccattc ttctaaaatc atttgtttat ttctgcctag
    11881 tctatctaat gattgtagat agagtaaatc tccttttcga aacatccgtt tcattaattg
    11941 atattcaggg cgtttaaaat ctttgccgct ggctttttct acaaatatat attcttcagg
    12001 gattcctaat tccttcgcgg aaatcagttg tcgttcgatc gattgatcat aactactgac
    12061 ccggatataa aaaaattttc tcatcgtttt tatctaccct tttttcacta aaattgtttc
    12121 aaaacaatca gattaaatca gaaacgtttc aaattgtatt atgtggttat tatgccatac
    12181 ataaacaaag aaaatcaagg catgtcaaaa agtatacttt ttgaaacagt aagtttacac
    12241 tcccgcatga ttatatttat tccgctaaaa tacataaaaa tggcaggcct taacggtctg
    12301 ccattaaata aactagttat ccagtttttc ttttatgtct tccatggtat attttatttt
    12361 tcacatcaga atttgacttc tttaactttt acaatttttt taacactatt attctattac
    12421 aacactatat atttctaatt tagggttaaa aataaatctt tttgatactt ttgcctttac
    12481 aatataattg tattctttct ttttttcttt gaagtcgctt gattcaactg taacttcaaa
    12541 ccacatttca tttggagact cttttaattt ttttacttga aatgaattat ctcttggatc
    12601 ataaggtggt actctttcaa actcaggaag ttttctctgt atttgttctt caggagtatt
    12661 cgcaaagtaa tctactatct tgacagttat taaaagtact actattccca aaactataac
    12721 aaacataaag ataattccac atccagaatt atttttatta ttttgagtca gattattcca
    12781 ttctatttct tccataatca tcat
//
LOCUS       DADVXM010000069        12721 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.073, whole genome shotgun sequence.
ACCESSION   DADVXM010000069 DADVXM010000000
VERSION     DADVXM010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.073"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..430)
                     /locus_tag="KB927_002083"
     CDS             complement(<1..430)
                     /locus_tag="KB927_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBB6840990.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
     gene            complement(462..1040)
                     /locus_tag="KB927_002084"
     CDS             complement(462..1040)
                     /locus_tag="KB927_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HBB6840991.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGAFDVHPKS"
     gene            complement(1056..1535)
                     /locus_tag="KB927_002085"
     CDS             complement(1056..1535)
                     /locus_tag="KB927_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBB6840992.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1541..2565)
                     /locus_tag="KB927_002086"
                     /pseudo
     CDS             complement(1541..2565)
                     /locus_tag="KB927_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2582..3688)
                     /locus_tag="KB927_002087"
     CDS             complement(2582..3688)
                     /locus_tag="KB927_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBB6840993.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3917..6514)
                     /gene="adhE"
                     /locus_tag="KB927_002088"
                     /gene_synonym="adhC"
     CDS             complement(3917..6514)
                     /gene="adhE"
                     /locus_tag="KB927_002088"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBB6840994.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6819..7199)
                     /gene="yajC"
                     /locus_tag="KB927_002089"
     CDS             complement(6819..7199)
                     /gene="yajC"
                     /locus_tag="KB927_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBB6840995.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(7296..8441)
                     /gene="tgt"
                     /locus_tag="KB927_002090"
     CDS             complement(7296..8441)
                     /gene="tgt"
                     /locus_tag="KB927_002090"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBB6840996.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8659..9357
                     /locus_tag="KB927_002091"
     CDS             8659..9357
                     /locus_tag="KB927_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBB6840997.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9525..12164)
                     /locus_tag="KB927_002092"
     CDS             complement(9525..12164)
                     /locus_tag="KB927_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6840998.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
BASE COUNT         3556 a         2798 c         2257 g         4110 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatttctag tctaactttt ggggtgcaca
      481 tcaaaagcgc ctacgagata acctcccata aacaaagcag agatcgaagc accaccagca
      541 acaagtgaat acatgataaa agcagtactt ggaggaatga ccatacctgt cggagctgac
      601 gcgatattga ccgctgtcgc aaacttccgg tcatatcctt cttccacttg ctgagggatc
      661 aacactccac caatcgcggt agaagcggca atggccgagc tagagatgga accaaataaa
      721 gcattcccta acacattcgt atgagccaaa gcccccggca cgcgcccgac gaacaacatc
      781 gcaaaatcca ctagtttctt agctatccct ccattattca tgataatgcc cgagagaacg
      841 aaaaacggaa tagcgatcag cgaaaaacta ttgatacttc ccaccatttt ttgagctgaa
      901 ctaaaagcag aaacatcaaa cggtataact aacaataaag tcatcatcga tgagaatgca
      961 atacttatag caatcggcat ccctaataca agcaacacaa caaatacaaa aaataacact
     1021 aatccggctt ctattgccat tttattcctc catttttata ttttttcttg aattgctggc
     1081 ttgttgctta atgtatcgat tagattgatc aggctataga taatgatgag tacccccgat
     1141 acaggtactg acagataaac atatcccata ggaatactta aagaaggcga gatctgcccc
     1201 attgtcaatg tgacagcatt ccatccgcca tacaccatga tcatcgcagc aaataccaga
     1261 aataaacttt gaacaacaac ttctaaaatt ttactttttt tgccagttaa tttttcactt
     1321 aaaaccgtta cggctaaacg tgctttttgt cccacaacat acgcggaaga caacatggca
     1381 aaccagacaa gaccgaatcg aacaagctct tccgtgaccg tatttggatt tcctaaaacc
     1441 gttctggaaa atacttgcca taaaacaaca gcgaccatcc caacaagcaa aacagctccc
     1501 aggatctcta ataccttgtt taaaatcatt ttcattacag ctacgctcct tgctcttgga
     1561 tcttttgata aaggtctttg taggtaggat cgtttttgaa tatatcatga agtggggcaa
     1621 ctgcctctcg aaacggtgta ttatctacat cattgaattg gactccatgt tcttcttgtg
     1681 ctaaagcttt ttcttcttca attgcttttg caaaagcttc aatttcaaaa accgttgatt
     1741 ctttcgctgc ttcttcaatg gctttttcct gttcatcagt tagctgttct ttgatggcat
     1801 cattcatgat gatgatatct ggcacacgtg tatgctcatc ataggaatag tatttagcta
     1861 ccccgccatg tccagctgta tacaagacaa attcattgtt ttctgatccg ttgatcaaat
     1921 tggattgaag agacgtgtac acttcatcac ttcccatagg tacgggcgaa ccgcctaaaa
     1981 gctctaccat tttgatagcg gtttcgcttt gcatcacacg gatcttcttt cccttcaaat
     2041 cttccggcgt atggatcgga ccgtctacca tataaaagct gcgctgacca gaatcataat
     2101 aggtcaatcc ggtaaatcct aaatttttgg tcgattggta gattggctcc attatttctt
     2161 cattatccat caccttaaag aaatgttctt catcattgaa tagataagga acggaaaaaa
     2221 tcgaataatc tttagagaaa ctttccaacg ctgaggcact tacttttgtg aaatctactg
     2281 ctcctgactg tgtcaattcg atcagttcac gttctccacc cagttgtcca tctgggaaat
     2341 actggatctg tacggaacca tctgtttttt cttttactaa acgcccaaat tcattcattg
     2401 catcaattac tggctgttgc ttgcataagc aaagcgcaag gtaactatct catttacgtc
     2461 tgcatctgcg acagttgcca cactagaatt atttccgcag ccgcttagac ctagcagacc
     2521 taggctaagc gaacttgctg caaacagcag tgatgttttt ttcatatggg tttcctttct
     2581 tttaacaata agagacgagc aattctgtca aacaaagcac cgttaacgac tgtccataag
     2641 gcattgctgt gattccgata ttccgataaa aatctaaact gtcccccatt cctgtcccga
     2701 ttgaaacgtt ttgaacttct cctttttcat cgatttgttc aagcaatcct tggatagcac
     2761 gataagcgac ttctttatat tcttgtggta aataacgttt atggaccgct ttcaaaatac
     2821 cgtaagcaaa tcctgcagtt gcagaagatt ctacgtaaga agaaggatca tccaacaacg
     2881 tatgccataa accgctttca gactgataag tttttaatgc acgcacttgt gcttcaagtg
     2941 tttcgatcaa taatttgcgc aatgcatctt ctttcgataa ttctaagatt tcaatgatct
     3001 ctggaatagc aatcgtcaac cagcagtttc cacgagccca aaatgcttcg gcatagttat
     3061 gatttccttc aaacgtccag ccgtgatacc acaatcctgt tcgtttatcc atcaagtatt
     3121 tgatatggat cataaactgg taacgagctt cttctaaata ttctgggcga ttcaacagtt
     3181 tcccgatttt tgccaaagga agcactgtca tcatcaatgt atcgtcccac aactgattct
     3241 tattttccgg tccatatgtg gcatgctgta acccgtcttc atttgtccga ggcatgtcat
     3301 tcatgaccca ttctgcccat tgttctaaat aaggcaaata gcgtgaatct ttcgtgtctt
     3361 catacaagta agccatagtc aatagcggtg ccattgtatt gacgtttttg ggcggagcgc
     3421 cttcttccat acgatcctca aaccattcat tgaccacttg ataagcgcga ggattttttg
     3481 tcatctggta atttttataa ataccatata gaccgacacc ttgtggccaa ttccacactg
     3541 tccagctttt gtcatctact ttcagtccat caaagtccaa caaaaattca ccattatcgt
     3601 ctttgatcgt tgtcaggttt tcaacgagca ggtcaatttt ttctttcact aattctttag
     3661 gtacaaaaat ctcttcttta ataatcatct ttacgccacc tttttaaacg ctttcatttt
     3721 atatccttaa tatagcagta ataccgtcca ctataaatat cgctttttga acaaaaactg
     3781 tctaaaattg acctaaatgt taaataacaa aagtaacttt cagttacttg gaaattaaaa
     3841 aaagaacttg gagaaacaac gttttccaag ttctttttca tctattttct tatctttttt
     3901 ctacgctttc ttttgcttat ccgttgtaag catcaatgat gatctgtttc aattcagaga
     3961 tcaatggttc tttcggatta gctgtcgtac attggtcttc gtaagctaat tcagccatac
     4021 ggtctacggt tgtatctagt gtttcttgtg tgactccttg agcttttaga ctcatgttga
     4081 tgccgacaga ttttcctaat tcataaacag ccgttgctaa agcttcgact aattcctctg
     4141 ttgtttcgcc tttcagacct aagaattttg cgatatctgc gtaatctgta tctgcacgga
     4201 aatagtcata tttagggaac atcgcatgtt tttgtggatc ttttgcatta tagcggataa
     4261 tatgcggtaa aagaatcgca tttgtccgtc catgagggat cccgtattcc ccgccgattt
     4321 tatgtgcgac tgagtgacaa atacctagga atgcgttagc aaacgccata ccagccattg
     4381 tagaagcgtt gtgcattttt tcacgtgatt ccatatcagg tgtttttact gatttttcta
     4441 aatagtcaaa gactaacttg attgcttgta ggctcaatcc acgtgtataa tctgaagcca
     4501 tgactgaaac ataggattcg attgcatgtg ttaacacatc catcccggta tctgctgtga
     4561 cagatgctgg aactgacatg acgaattgag gatcgacgat tgcgacatct ggcgtcaatg
     4621 cataatctgc taacggatat ttcacatgtg tttcactgtc agtgatgacc gcaaatggcg
     4681 ttacttcaga accagtccct gatgttgtcg ggatacatac gaattgtgtt ttttctggtt
     4741 tgtcgatctt atatgtccgt ttacggatat ccaagaattt ttgttttgca ccaaagaaag
     4801 atgtgtctgg gtgttcatag aacatccaca ttcccttagc tgcgtccatt gcagaaccgc
     4861 ctccaagagc gattactgta tctggcttga agtctgccat cagtttcgtt cctgcgtata
     4921 cggtatttgt cgatgggttc ggttcaacat ctgagaagac ttcgatcttc acatcatttt
     4981 tacgtcgtgc caatacttca cgaactgtat cgcagtaacc gaattggacc ataccagggt
     5041 cacaaacgat catgacacgt tcaacgtttt ccattttctc taagtacaat agagagttct
     5101 tttcaaagaa gatttttggc ggtaatttga accattgcat gttatttctc cgtttcgcta
     5161 cagttttgac attgattaag tttacagcag agacgttacg agaaacagag ttcttaccat
     5221 aagaaccgca tcccaaagtc aatgacggaa tcatttcgtt atagatatca ccgatgccgc
     5281 cttctgcaga tggtgtattc actaaaatac gacaagcttt cattcgaaga ccgaatttga
     5341 catgcaactc ttcgttttct gaatggataa ctgctgtatg tcctaatcct ccaagattca
     5401 acataccttc acacaaatca aacgcatggt ccgtgttgtt agctttgatc atggcaagaa
     5461 ctggagaaag tttttctctt gatagcggat aatctgggcc tacgccttcc aattcagcaa
     5521 tcagcatttt cgttcctttt ggtacactga ttcctgccaa ttttgcgatt tccatcgcag
     5581 aatgtccaac gattgatgga ttgaccgcat attttccttc gttcatcact gcatcttcta
     5641 atttttgcaa ttcatctggt tttacgatat aaacttggtg tgcttggaat tctgctttta
     5701 ctgctgcata gatttcttta tccacgatca cagcttgttc agaagcacaa atcattccat
     5761 tatcaaatgt tttcgaaacg atcaaatcgt tcactgcacg tttaattttt gctgtttttt
     5821 caatataagc tggtacgtta cctggaccta cacctaaagc tggttttcct gtagagtaag
     5881 cagacttgac cattccagct ccacctgtcg ctaagacgat cgcgatacct ggatggttca
     5941 ttagcataga agtcgcttcg atcgaaggat gttcgatcca ttggatacaa ttttcaggag
     6001 ctccggcagc gatagcagca tcacgtacca ctcgtgctgc ttctgcagaa gatttttggg
     6061 cacttggatg gaaagcaaaa acgattggat ttcttgtttt caacgcgatc attgatttga
     6121 aaatcgttgt ggaagtcgga ttcgttgttg gagttactcc gcaaaccaca ccgactggtt
     6181 cagcaatttc aatcaaccct ttttggacat cttcattgat cacaccaact gttttatcat
     6241 gtttgatatt atgccaaata tattcggacg catacatatt tttgattgct ttatcttcgt
     6301 aaacaccgcg gcctgtttcc tctacagcca tcttcgctaa tggcatatgt tgatccaaag
     6361 ctgccattgc catttcatgc acgatatggt ctactttttc ttgatcaaag ctttccattt
     6421 ctttcaatgc tgcatttgct ttttctgcca aatcatcaat cattgcttgt acgtcaattg
     6481 tcttcgtttt ttctttttct attactttag ccatcattat cctcctaatg ggtcatggtt
     6541 atttgttaaa taattcacat gtatatcata caatatttat ttttctatgt aaacactttt
     6601 ttgtgatttt tttcacagtt atttttaaat ataaaattgc tttatttaca ggtgtttgta
     6661 tagaaaaata tataaagtta tttattatta tttatatgac acacccgatt attcaatatt
     6721 gagcaatata tcccatgctc ttatctcttt cttttttgaa taaaaaatga ggtaggacat
     6781 ctttctgccc tacctcgtct ttaaataagc tttgatactt atttttcttc cttctcttct
     6841 gtctcttcca gcgtttctgt tgtttcagtt tttacttcaa ctgtctcagc tggttcttct
     6901 gttgtttcaa cagtagtcgt tgcatcattt gttacgacag tccctggttt gaccgttttg
     6961 attgctgcac gatcgtactc aaggaagatc ccttcgcagt ctaaaacaac tgtccgtttg
     7021 tcattgtcga tttctgaaac aactccatgt aatccgccga tcgttacgac tgaatcacct
     7081 ggtttcatgc tatctaacaa gttttgacgt tcttgctgtt gtttcttttg cgaacgtgac
     7141 ataaaaaacc acattgctaa tagcgcgata aacatcacaa gcattggtaa tgttcccatt
     7201 tttttcacct cactaattct gtatctacaa aaaacacttt agcagaaaaa tgctgataac
     7261 actagttttt tacttaattt ttaaaagatt ttcctttaga agctttttgc gttttcttta
     7321 ttgaacccgt attcttcaaa aaaggcttct ctaaattcaa gcaaattatc atccatgatt
     7381 gcttgacgta cttgtttcat tagattcaac aagaagtata aattgtggta agaagtcaaa
     7441 cgaatcccaa atgtttcatc acatttgatc aaatggcgga tataggcacg tgtatagttt
     7501 ttacatgtat aacaatcaca tttctcatca attggacgga aatcatgggc atatttcgca
     7561 tttttcacta ctagacggcc ttgagaagtc atacatgtgc catttcgagc gattcgagta
     7621 ggcaagacac agtcaaacat gtctactcca cggataacac catcgatcaa tgaatcagca
     7681 gcaccgacac ccatcaagta acgtggtttg ttttcgggga tcaacggtgt agtgaattct
     7741 aatacacgat tcatttctga tttaggttcc ccgacagata acccgccgat tgagtaacca
     7801 gggaaatcca tcccgactag atctttcgcg ctttgacgac gaagatcttc aaaccctgct
     7861 ccttggatga ttccaaataa tccttgacgg tctggattag catgagcttt caatcctcgt
     7921 tctgcccatc gagacgtacg ttctactgat tttttcacgt agtcgtaact ttcatcgaat
     7981 ggtggacatt cgtcaaaact catcatgata tcagagccca atttattttg gatgttgatt
     8041 gctttttctg gtgataaaaa catacgcgaa ccgttcaagt gatttttgaa atgcacgcct
     8101 tcttcttcga tattccgcat atcacttaat gaaaaaactt gaaagccgcc tgaatctgtt
     8161 aaaatcggtt gatcccagtt cataaattta tgcagtccgc cagcttcttc tactaagtct
     8221 tcaccagggc gtagccataa atgatatgta ttacttaaaa taacgccagc acccatttct
     8281 ttcaactctt ctggggacat tgtttttact gtagctaatg ttcctactgg catgaacatt
     8341 ggtgtgggga aagttccgtg tggcgtgatc aattccccta aacgcgcgcc agtatgtttt
     8401 tctttcttga ttaaacgata gcgaatggca ggttgcgtca ttcatttccc tactttctat
     8461 ataaaatatc ttgacaactc ccaccatcat aatcgtttca agtgcttttt gcaagttccc
     8521 tcggcttcct tctactttat ttaatattct tttttttatc ctttttttat gaataacaaa
     8581 aaaaagaaaa acattatgac agaaatattt tttgatacat ggtatattgg tgttattaaa
     8641 gaaaaggagg gaaaaatcat gcaatcttct gcagaattaa aacgccaagc aaaagagagt
     8701 ctaaaaggac gttggggaca agctgtttta ctaaatctaa tccctacatt gattggtatt
     8761 gctactattc ttcttattat gattcctatt atcttgtttg ccaccaccat atatgatgga
     8821 tcagcgagcg tctcagaagc gacaacttca ggaggcggta gttcaggagg cggtggcgga
     8881 attatttcca gcatcattag cgctttgttc atgagcggta tttcttggac ttatcttgat
     8941 attttacgtg gacaaaaaga tcagatcgaa ccattcaaag atgcatttcg tggattcaaa
     9001 ggtttgttta tcggcggagt gatcagctta gctgtgctga tctcgatctt tacaacatta
     9061 tggggtttgc tattagttat tcctggaatc attaaaagct attcttattc tcaaagctat
     9121 tttatttact acgatatcgt ccaagaaaca ggacaaacac ctaaagtact ggatacgatc
     9181 actgcaagtc gaaaattgat ggatggttat aaaggacaac ttttctggtt agatctttca
     9241 tttatcggct ggcatatctt agcattagca actgctggta ttggttatct atggctcagc
     9301 ccatacattt ctgcaacaaa agcagcattt tatgaacaat tgccaaaaga tatttaaaag
     9361 agagtgtgac ttgtgaccga gggggtggca ggagaacacc gtttatcgag aggcagtaaa
     9421 agaaacattc agcccattag caaaaaggag gtgtgacaac attcatgtca cacctccttt
     9481 ttgtatagtt ccagtaaaaa gaaaatcaac ttagaaacag ttaatcattc ctcttcttct
     9541 gcttccggta atcgatggaa cttgatcagt tcattcaccg cgattggtac gatagataaa
     9601 atccctacca agaaccagtg attcaaactg atgtgtacta ggccgaatag ttcttgcgta
     9661 aatggcagca aagcaacagc cgttgtaata gctaatgcca gtaacgccat ttctaccaaa
     9721 gctttattgg tcgctaaatt gactttgaag atcgattggc tgctgcgtac attgaacaca
     9781 tgcagaatcg atgaataagc taagatcaag aatgcaacag tttgaccgac atgctgactt
     9841 gcgtctaccc atgggctgat agtatcgaca taactaccta aataataacc aaacaaggtt
     9901 acgatggtga agacccctgc atttatggca attttttgca ataaacctcg agcaaagatc
     9961 ccttcatttt tcggaatggg tggctgatcc atgatgccgt gttccgctgg ctctcttcct
    10021 aaagcaaatc ctggaagtcc atcagcaact acattgacaa acagtagttg cacagctgta
    10081 aatggtgctc cccatcctaa cagcatcgca atcaaaacaa taaagatctc cgaaatatta
    10141 cagcttagca aaaagttgat agctttacga atattctgat aaaccgaacg tccttgactg
    10201 acagcgtcta cgatcgtcgc aaagttgtca tccgtcaaaa tcatatctgc ggcactttgc
    10261 gccacatctg ttcctgtgat ccccatggca cacccaacgt tacttgcttt caacgctggt
    10321 gcatcattca caccatcccc agtcatcgct acgactgcac ccgtacgttg ccaagatttg
    10381 acgatccgga tcttgtcttc tggcgttacc cgagcataga cagagagagc tttgacacgc
    10441 gcatctaatt cttcgtctga taattgatgc agttctgatc ctgaaagtgc ttctgacgga
    10501 tcattcaaga tacctaattc tttcgctatg gcactggcag tcaccacatg atctccagtg
    10561 atcatgactg ttttgatgcc agcctttttc gctcgcttga ttgctccttt actttctgga
    10621 cgtggtggat cgatcattcc gatcagacca atcaaacgta agtctttttc cagtgcttca
    10681 gaagaaatat cttgcggttc ttcgtcataa gtagcataac caacagcaat cactctcagt
    10741 gcccgtttac caaagcgatc attaacgatc gccgcttgtt ctacatcgcc tgaactaaag
    10801 cgcggagcaa gaacatcgaa tgctcctttg gtgattgaga tgtatttttc gcccatttgg
    10861 tgaactgttg tcatcatttt tcgttcagaa tcaaaaggaa gctcgtttac tcgtggatat
    10921 ttttcttcta attctgcctt tgtatgataa ttctcttcaa cagcccttac gatggctact
    10981 tctgttggat tacctttgat aacaaggtcg tcatcttctt gctcgaccgt cacatctgta
    11041 catagtgcag ccattttcaa tatttccatc gcgctgttcg tcattgaatc ttcgatattc
    11101 gttacttcat cttctttgct ccatacccgg cggacgcgca tttcattttg tgtcagcgtt
    11161 cctgttttgt ctgagcagat aacattagcg gttcctagcg tttcaactgc tggcaactgt
    11221 cggatgatcg catgtttcct cgccatcttc tgcacaccgt atgcaagtgt caacgtaaca
    11281 ataacagtca aggtttccgg tacagctgca acagccaagg aaatcgaagt catgaacatc
    11341 tcaaggagtg gttctccttg cagttcacca atcacaaata ctaaagccgc agccgctaaa
    11401 gcgatcatac tgattcgttt gcctagctga ttcaatcgga cctgtaaagg tgttttttgc
    11461 atagtatttt cgttcaaaag atccgcgatc ttacccattt ctgtagccat gccaatggca
    11521 gtgacgatcg ctttcccacg acctgcagca accgtacatc ctttaaatac catattaagt
    11581 tggtcaccta atgactcatc ttcttcagca ataaatgctg catctttttc aactgcttca
    11641 ctttctccag tcaacgccga ttcttctaca cgtaattgtg atgcttcgat caaacgggca
    11701 tcggcagaaa tagcatcacc ggactctaaa acaagaatat cacccactac cagttgctct
    11761 gactcaacag tggtcacttt gccgtctcgt atgacagttg ccgtttgttt attcatatct
    11821 tgcaaggatt ccagtgcttt ttctgcgttt ccttcttgga caatcgccaa taccgagttg
    11881 atcacaacga tagcgatgat cagcagtcct tcaaataaat ccccatgttc tgtagcaaat
    11941 gcggtataaa aggaaatcac cgctgctaca agaaggatga tcgttgtaaa atcggacaag
    12001 cttcgaaaga attttttgat catcgattct ttcggcgcct catcgaattt attcaatccc
    12061 tgcttttttc gccgttcatc cacttcttgt gaagacaacc cagtatctgg atctgcttct
    12121 gttaccttct ttacttcttc tattgtctgc ttgtattctt ccatcctatt cctcctttaa
    12181 aatcttcgta caaaaaaagg tacttatttt actataacat ccttttttta tttacttcaa
    12241 ataaagggct tatcgattat ttgttaagaa agcgtaaaat ttaaagtgct tatatttgca
    12301 aacgctacca aaggatgcta ttatatagat gtaaggaagg aggataccat caaatagaca
    12361 gaagaatttc tcgatagaac agtgtaagca aacaaagttg ttagaagtac aggtttcacc
    12421 cagacatgcg tgtagagtac aaacctataa atagtgaatg cgtatggatg tttggatcac
    12481 gaagtatccg aaacaagaag taatgcgata cgtaacaatt gaataacgta aacgtctgaa
    12541 aattgaatag gaacaagaga tgtttcaaat gttgaagatg taacgaaaac aaaatttttg
    12601 tttaacatga agaaattcaa caccgtgctt tgcatgtatg atggaaagtt acaatcattt
    12661 ctgtttattt gaatccttcc gaggtacaag aaagccgagc ttatcgagag ctcggctttt
    12721 t
//
LOCUS       DADVXM010000070        12708 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.074, whole genome shotgun sequence.
ACCESSION   DADVXM010000070 DADVXM010000000
VERSION     DADVXM010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12708
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.074"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            61..676
                     /locus_tag="KB927_002093"
                     /pseudo
     CDS             61..676
                     /locus_tag="KB927_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(816..1856)
                     /locus_tag="KB927_002094"
     CDS             complement(816..1856)
                     /locus_tag="KB927_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6840999.1"
                     /translation="MASIVKRGKSYRAQVSLYKNGQHKKLSKTFATKKEATLWALEME
                     LAKGEGKELAERTTTFADFFENWIYLVKVNDIKETTFQNYVRTLGVIRNLFEDIQLKD
                     LNDIVVQKKIDEYAETHSRKTTHEVLLKIKTALRDAYARGYIANDFARLVKTRGVNPP
                     KRNKALSITNFKKLRNYVLQHPEDEFNVLVLLALETGMRRGELLAIKPENLYEYGIEV
                     RHSISPTSDDTSLKTQNAKRDVSINKEVYELIRQIPVKENGYIFSFGGFKQSEQLAEL
                     LESLGIEKTTFHGLRDTHASFLFAQDIDIAYVSKRLGHINIQTTQNYYLELMPEKKHQ
                     QDADALNLLSSL"
     gene            complement(1951..2148)
                     /locus_tag="KB927_002095"
     CDS             complement(1951..2148)
                     /locus_tag="KB927_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841000.1"
                     /translation="MSINKNTKDYPYLLTREQASRFLGIDPKSFDKYIRPHNDLERFM
                     VGKHERYTMKSLIDFIESQSV"
     gene            complement(2192..2395)
                     /locus_tag="KB927_002096"
     CDS             complement(2192..2395)
                     /locus_tag="KB927_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841001.1"
                     /translation="MSNKKAMENINHIIEMIDFFQSGNGVINKKDNDSDYLRHIYTPE
                     DILGNLQHSAKEALKQLKNGELK"
     gene            complement(2405..2893)
                     /locus_tag="KB927_002097"
     CDS             complement(2405..2893)
                     /locus_tag="KB927_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841002.1"
                     /translation="MKHMRHIAKEVDDWTRVEAEFSGDYAHQLTDAIKECSTDEQLKN
                     LIISSLLDRYMFFYVNSNRPHKITRLMLELLDEKNFHFESPSPRNNLLEQSIDHLIKG
                     SGLLPTLWKVQQIWGGDTAKELIDYLYKQYYEEFEPNDDHIAWVNKYKNIYLLDGKPW
                     KE"
     gene            complement(2890..3084)
                     /locus_tag="KB927_002098"
     CDS             complement(2890..3084)
                     /locus_tag="KB927_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841003.1"
                     /translation="MASTNKSYLQKVIDDNKEKPYKRNNSKVTDVSKDFQAQTLYIGA
                     RSRNTKVHLRIYDKKEEQLS"
     gene            complement(3071..3562)
                     /locus_tag="KB927_002099"
     CDS             complement(3071..3562)
                     /locus_tag="KB927_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841004.1"
                     /translation="MIKPDIDQFTLVLQTTGVFDFDEWRDWVAKSLISTFLIKSKMHK
                     LFDNFGEADVKLPEGYTIGYSFINAPFYFCIAYHEAFSKMGVIVKYSAYAWHEYRKRY
                     EAEFNEPIHLHTFLKMIDSDEYSFRLSRIDICYDFINEGIDIAKLKRSIEEKRTELRY
                     GKY"
     gene            complement(3791..5092)
                     /locus_tag="KB927_002100"
     CDS             complement(3791..5092)
                     /locus_tag="KB927_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBB6841005.1"
                     /translation="MKKTYRMQRGFISFLFIGFFLILWFFFSKLYPLIVEQITIIQLP
                     HIESNIFLFPVGLVVVGLFVSWSIRNKLWFGLFFSVHYYLMIKRIRRHVKDARFEDER
                     EFDNRLVKLPIIKIEFDDNRARKSGKVFIQNSIKFDKKLEDMRIDAALEGYVSERQYL
                     SKDRNWYIYEFYDVDSQKQLEIKSASDLIEWSNKKTDDYSLRLDERATVPFHHMGLVG
                     QTGSGKSFFIQMLVEQVLSKKVSHELFVIDPKRTDVYQMAKRTVGDERTADKTNAIEL
                     INQFHERMKKRQDELQDYFISNRNKTYRDAGLPALILLIDEFGALRESWKTLAKKERD
                     EVDSILSDVAFMGRQLGCILWVATQQMNAQTMPTAIREQLVLKIALGDSDEQTYRTLF
                     SSGVDIPPVQFTAGQGIYSYPGLASVDKPRMLAVPYCSYLE"
     gene            complement(5204..5482)
                     /locus_tag="KB927_002101"
     CDS             complement(5204..5482)
                     /locus_tag="KB927_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841006.1"
                     /translation="MAHEPWNEYEDGQVTKELGTKYKCVIATDNTKYEGNDVQPDLNA
                     GEQIDVKVTQPPKSYKKFSRITFVNPTASVYGTFMNELSVKADDVDIV"
     gene            6060..6314
                     /locus_tag="KB927_002102"
     CDS             6060..6314
                     /locus_tag="KB927_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841007.1"
                     /translation="MTDVDRRQQDIDDMYDYKVPALNKIREDKLEMCFRKLFPDVKFD
                     IEYLEKILFTINEPSMHSDLEYGQAIVDLKEKAYIKNYKD"
     gene            6728..7171
                     /locus_tag="KB927_002103"
     CDS             6728..7171
                     /locus_tag="KB927_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003726066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBB6841008.1"
                     /translation="METILEIVRIEQVICEAEEGVNYTIKGPKDGAEIASRFIGRDDR
                     EVFFVMCLNTKNHVVAVHRCHVGSLNASIVHPREVFKSAILNNAASIIVAHQHPSGDI
                     TPSMEDINVTKRLVEAGKLLGIEVFDHLVVNGDSKFTSLKEKGHF"
     gene            7299..8045
                     /locus_tag="KB927_002104"
     CDS             7299..8045
                     /locus_tag="KB927_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010721123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HBB6841009.1"
                     /translation="MTEEIIKCKTRVQKHGEVFTPKRIVNQMLDIPEIKEACENLTTT
                     FLEPSAGEGAFLVEILERKLKMVSEKYNKDLVQFENYSLLALTTLYGIELLEDNAQTC
                     VMNMFQKYYDYYKEQIQYHKGKMNQKVLDSAKRIISLNIGNGNFLTRKAVDGTPLIFS
                     EWEAINLRKNTKNIKVQRTEYTFDEIYENTQKENGKALRQPKTEPEQIDIFSFLDEPI
                     DKKEEVVKEMQYIPVKIIDVYKEEMEEANG"
     gene            8038..12378
                     /locus_tag="KB927_002105"
     CDS             8038..12378
                     /locus_tag="KB927_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HBB6841010.1"
                     /translation="MDKTVIKPFQEIKYKVYGYTLPEVPNHDGYVKIGDTTRDAVTRI
                     FEQVGTAGLNPKILFEKLARKSDGKWFRDKDLHKFLILNGIEKKNFNSRADEWFYFNG
                     TLEKAEELTNKYINRDYDEIQIDDKRSDYVLRNEQQQAVEKTYEYYQSKQEPKEFLWN
                     AKPRFGKTLTTFDFIRNLNATNVLIVTNRPAIANSWFDDFHKFIAWQEPQMKFVSETD
                     ALNGKAMTRDQYLEFIYTTSHVNPTQIAFISLQDLKGAEFAGGMYKKLEWVAGLNWDL
                     LVIDEAHEGIDTRKTDIAFSQLKREFTLHLSGTPFKALAKGDFSEEQIFNWSYVDEQE
                     AKENWDPTIGSNPYESLPTLNLFTYQMSKMIEDEVSAGLTIEEEKNVDYAFDLNEFFR
                     VKENGRFEYEESVVRFLDNLSSGKFPFSENQYRNELNHTFWLLPRVNAAKALEKLLNA
                     HPTFKDYKVVLAAGDGVSLHDGAEAEALDLKENTKSFDKVRNAIEQNDKTITLSVGQL
                     TTGVTIPEWTAVFMLNNIESPSLYFQAAFRSQNPYEYEKDGKLFRKENAYIFDFSPDR
                     TLRLYDEFANNLSSGSSKTSEERKRKIKKLLNFFPVIAEDEEGTMHEIDASEVLTIPT
                     RITSREVVKRGFMSNLLFANISGIFSGDSPFKEILDKIPPEKNKRLEKPREVSITDPH
                     LNDEGEVEIPKEVVLGKSKELFGEKIYSSIEVVDEVVSSFEEAEEKQKESIKKLAKDI
                     TASFSDGFNNLKESFKLNKGQTEKLKESVNNSIEDIITEKSLTLSNQVKEIEEEYTKK
                     KQEAEKKNDETELKAAIQQYEEEKQKIEESFADDINKEVENTINTAVEEQIEKVEEKK
                     KKTTEDDVRDHLRGFARTIPAFLMAYGDNQTRLENFEENIDEATFEDITSITIEEFKK
                     LRDGFEYEDDNGNRKVIHGLFNEVVFNASIREFLDTKKRLANYFDESLEEDIFDYIPP
                     QKTNQIFTPKRVVKKMVDKLEEENPGIFSDRTKRFADLYAKSGLYITEIVKKLNEGLK
                     GQIPNQQERIKWILENQVYACAPSNIICNIVKNFVYSHTINVSTKNLIEVDTMKLASE
                     EKLSTEIYELFGDDRLKFDVIIGNPPYQDETIGENKTYAPPIYHKFLEESYKLADKVE
                     MIHPARFLFDAGSTPKAWNRKMLADENLKVIDYVDDSSKVFPNTDIKGGIAITYRDAQ
                     KRIGPIGTFTKYPELNTILRKVKMDNFNSIDKIIYSADSYKFTQALHDDYPDAEARLS
                     KGHAFDVRSNVFDSIGHIFKNEKPSDNSEYIRIIGRQNHKRIEKWVKRDYIGEHPNLD
                     KYSVLLPGSNGNGDFGETFASPIIKEAAVAHTQTFISIGHFDNIIEAQNLLKYVKTKF
                     ARAMLGILKATQANSRPKWKWVPMQNFTNESDIDWSESISEIDKQLYKKYNLNQNEIQ
                     FIEDKVKPME"
BASE COUNT         4448 a         1996 c         2326 g         3938 t
ORIGIN      
        1 agagttgggc aacagaattt aaaaatgatc cggatttcag aattttaaag gagttttatt
       61 atggcgaaaa ttgggtatgc tcgagtaagc agcttagatc aaaatttaga ccgacaatta
      121 gaattattat cagagtgtga taaaattttt agtgataaag caagtgggaa agataccaat
      181 cgagaaggat ttcaagaaat gatgaaattc atacgtgaag gtgatattgt cgttgtgaca
      241 gaattaaaac gacttggacg aaataataaa gagctaacag aaacgatgaa tttaattcag
      301 ctgaagaaag ctacactgga agttttgaat ttgccagcgt taacaggtat cactgatgat
      361 aatttacgtc gattacttaa taacttaatt atcgaactat acaagtacca ggccgaagaa
      421 gaacgtcggt atattcgcga agcaacaaca aggaattgca ctcgctaaag caaaagggaa
      481 atacaaggga ggtacgctaa aatatcgtga gaatgatccg cgacttcaat tagcatttaa
      541 tttgtttttg actggatcta cagataaaga agttgaagag ctaacaggga ttaatcgtag
      601 aacgtttaga agatatcgaa tgaaacatgg tattactaat gaagttaggg agcaaaaaaa
      661 taaatctttc agttgaggct aatataattt tgcaagaaac caggtcttaa gaaagctcgt
      721 aaagcttcac aattctcaaa acgttaatag gtttgcctat ataccaacgt ttacaaaggt
      781 tttttggttc aagttggttc aaatcagctt gaacctcata aagaacttaa cagatttaaa
      841 gcatcggcat cttgctggtg ctttttttct ggcattaatt ctaggtagta attttgggtt
      901 gtttggatgt taatatgccc taaccttttc gatacataag caatatcaat atcttgtgca
      961 aacaagaatg atgcatgtgt gtcacgtaaa ccatggaagg ttgttttttc aatacctaaa
     1021 ctctccaata gctccgctaa ctgttcggac tgtttaaatc ctccaaaact aaaaatatac
     1081 ccattttctt ttaccggaat ttgacgaatt aactcatata cttctttgtt aattgacaca
     1141 tcacgctttg cgttttgtgt ttttaaagac gtatcatcag aagtaggact gattgaatgc
     1201 ctaacttcga taccgtactc gtaaaggttc tctggtttaa ttgcaagtag ttctccacgt
     1261 cgcatacctg tttcaagtgc aagtaataca agtacattaa attcatcttc tggatgctgt
     1321 aagacgtaat tacgaagctt cttgaagttt gtaatggata atgccttgtt gcgttttggc
     1381 ggattgacac cacgagtttt tacaagtcgt gcaaagtcat ttgcaatata tccccgagca
     1441 tatgcatcac gtaaagcggt tttaattttt aacaatactt catgtgttgt tttacgagaa
     1501 tgagtttccg catattcgtc aattttcttt tgaacaacaa tatcgtttaa atcttttaac
     1561 tgaatatctt cgaacaagtt gcgaatgact cccaatgttc gaacgtaatt ctgaaaagtc
     1621 gtttctttta tatcattcac ttttacaaga tagatccagt tttcaaagaa gtcagcaaat
     1681 gtcgttgttc gttctgcaag ttctttcccc tcaccttttg ctaattccat ttctaaagcc
     1741 cataaagtag cttctttttt ggttgcaaat gttttagaaa gctttttatg ctgtccgttc
     1801 ttatagagtg acacttgggc tctatatgac ttcccgcgtt ttacaatact agccatacta
     1861 tcaattcctt tcaaaaaata agttgataga tgctagttga atacacctgt attgtattct
     1921 gtaactagca taatatcaac tgttaaaaca ttagacagat tgtgattcga taaagtcaat
     1981 taaagatttc attgtatatc gttcgtgttt tcctaccata aaacgttcaa gatcattatg
     2041 tggacggata tatttgtcga atgactttgg gtctatgcca agaaaacgag atgcttgttc
     2101 acgagttaaa aggtaaggat agtctttagt gtttttattg atgctcatgt agcaccatct
     2161 cctttgtaat aaaataatat ccaagtaata atcacttcag ttctccattt tttaactgtt
     2221 ttaatgcctc tttagcagag tgttggagat tacctagaat gtcttcaggt gtatagatgt
     2281 gacgcaagta gtcagaatca ttatcttttt tattaatcac accattacca ctttgaaaaa
     2341 aatctatcat ttcaataatg tgattaatat tttccattgc ttttttattg ctcatatcgt
     2401 aatttcactc cttccaaggt ttaccatcaa gtaaatatat atttttatat ttgttcaccc
     2461 atgctatgtg atcatcattg ggttcgaatt cttcatagta ctgtttatat aaataatcaa
     2521 ttaattcttt tgctgtgtcg cctccccata tttgttgaac tttccacaat gtggggagta
     2581 gaccagaccc cttaattaaa tggtctatcg actgctctaa taagttattt cgtggagatg
     2641 gtgattcaaa gtgaaagttc ttttcatcta acaattcaag cattaatcta gttatcttat
     2701 gaggtcgatt agaattaaca taaaagaaca tgtagcgatc aagtagagaa ctaataatca
     2761 aatttttaag ctgttcatct gtactacatt ctttaattgc atctgttaat tgatgggcgt
     2821 aatcacctga aaactctgct tcaacacgtg tccagtcatc cacttcttta gcgatatggc
     2881 gcatgtgttt catgacagtt gttcctcttt tttatcataa atgcgtaaat gcacttttgt
     2941 atttctgctt cttgccccga tatacaatgt ttgtgcttga aagtctttgg atacgtcggt
     3001 cactttcgag ttgtttcttt tgtatggttt ttctttgttg tcatcaataa ctttttgtag
     3061 ataactttta ttagtacttg ccatatcgca attcagtcct tttttcttca attgagcgtt
     3121 ttaatttagc aatatcaata ccttcattaa taaagtcata acagatatca attcgtgaaa
     3181 gtctaaaact atattcatcc gaatcaatca tttttaaaaa ggtgtgtaaa tgaataggtt
     3241 cattaaattc tgcttcatat cgctttcgat actcatgcca tgcatatgca ctatatttga
     3301 caatcacacc cattttcgaa aatgcttcat gataagcgat acagaaataa aaaggtgcat
     3361 tgatgaatga gtaacctatt gtgtagcctt ctggtagctt aacgtcagct tcaccgaagt
     3421 tgtcaaatag cttatgcatc ttagatttaa tcaagaaagt acttattagg ctttttgcta
     3481 cccagtcacg ccattcatca aaatcaaaca cgcctgttgt ttgtaatacg agtgtaaatt
     3541 ggtcaatatc tggcttaatc atgttctatt cgctcctttt cctaagaaaa ctttaggtaa
     3601 agtttacttg gtgtaaaagc ctataagaat aggctttagt ctgggtttta ctcctgactg
     3661 gagctggggt gattaccaat cccccagctc tcctaaagga gggaagcacg gagcggaacc
     3721 tttccctgcc taacggcggg tccctttccg ctcattgtgc aaccgttcct taagaaaaag
     3781 ctaagtgcta ttattcaaga tagctacagt atgggacagc aagcattctc ggtttatcaa
     3841 cacttgctag ccctggataa ctgtaaatcc cttgaccagc agtaaattga actggaggta
     3901 tatccacacc agaagaaaac agagttctat aggtttgctc atcactatca cctaaagcaa
     3961 tcttcaaaac gagctgttct ctaatcgctg ttggcatcgt ctgtgcgttc atttgttgcg
     4021 tagcgaccca cagaatacac cctagttgac gacccatgaa agcaacatca gatagtatgc
     4081 tatcgacttc atcacgttct tttttcgcta aagtcttcca tgattctctt aatgccccga
     4141 attcatctat aagcaaaatt aaagccggca aaccagcatc cctatacgtt ttgttacgat
     4201 ttgatatgaa atagtcttgt aattcatctt gtcgtttttt catacgctca tgaaattgat
     4261 taatcaattc aatcgcattt gttttatcgg ctgttcgctc atcaccaacg gtacgtttag
     4321 ccatttggta aacgtcagta cgctttggat caattacgaa taactcatga ctgacctttt
     4381 ttgataatac ttgttcaact agcatttgaa taaaaaacga cttaccacta cctgtttgcc
     4441 caactaatcc catatgatga aacggtacag ttgcacgctc atctaaacgt agggagtaat
     4501 cgtcagtttt cttgtttgac cactcaatca agtcacttgc tgatttaatc tcaagttgtt
     4561 tttgtgaatc tacatcatag aactcataga tgtaccaatt acggtcttta gacaaatatt
     4621 gacgttcact tacgtatcct tctaacgctg catcaattct catgtcttct aacttcttgt
     4681 cgaatttaat tgagttttga ataaacactt ttcctgattt ccttgcgcga ttatcatcaa
     4741 attcaatttt gattatcggt aatttaacta aacgattatc aaactcacgt tcatcctcga
     4801 atctagcatc tttaacatgt cttctaattc tttttatcat caaataataa tgcacagaaa
     4861 aaaatagacc gaaccataat ttattgcgaa ttgaccaact aacgaacaaa ccaacaacca
     4921 ccaagcctac aggaaacaag aagatatttg actcaatatg tgggagctgt atgatcgtta
     4981 tttgttcaac aatcaatggg tacagtttag aaaagaaaaa ccataaaata agaaaaaatc
     5041 caatgaataa aaatgaaata aaaccacgtt gcatccgata cgttttcttc acatattcca
     5101 cgtcctaata ttgtggttcc gcccctgata aggggcggtc acaggtataa aagtgtattt
     5161 gacgatagaa agggaactga ctaccgttcg ttctttactt cggttaaaca atgtctacat
     5221 catctgcttt gacagaaagt tcattcatga acgttccata cacagaagct gtcggattca
     5281 caaacgtgat tctactaaat ttcttataac tctttggagg ttgtgtcact ttcacatcaa
     5341 tttgctcacc agcatttaaa tctggctgaa catcattgcc ttcatatttt gtgttatccg
     5401 tcgcaataac gcacttgtac ttagtaccta actcttttgt gacttggccg tcctcatact
     5461 cgttccacgg ttcatgagcc atcactcgaa cgtccttatc cttgaaaaaa acctcggcat
     5521 cgaacttatt aaactgtctt aatttcttca tagtgttttg cactccttta tttttgatct
     5581 acctatattt tagctaatac ttgccatttt atcaagacat gtcatcatga caaataacaa
     5641 aaattgttgc acttatagta tgttaatggt attataattt ataatgacat tcgataattt
     5701 ataacgacat ttatgggggt gttaaaatgt taaatgataa agcagatgat atgttaaatg
     5761 aagaggttgc acaaaatgaa atattagatt ttatagatat gaaatatggg gcaaaccaac
     5821 tcgtgactca aaggacaata caaagatggt tagaagagtt aggcattgac tgcatacaac
     5881 ctcgtccaaa gagaaatagg gatataaggt ataggaaatc tgatgtctta aagctagaag
     5941 aaataaagag aactaattta ttgaggaaaa agaacaagga attagcacgt aaagatatag
     6001 aaaaaatagc aaccgatatg cagaaaaaag aaatagagta taaccaatgg ttagctagca
     6061 tgacagatgt tgatagaaga cagcaagata ttgatgacat gtatgattat aaagtacctg
     6121 cattaaataa aattagagaa gacaaattgg aaatgtgttt tagaaagttg tttcccgatg
     6181 ttaagtttga tatagagtac ttagaaaaga ttttgtttac cataaatgaa ccatccatgc
     6241 attcagattt agaatacgga caagcaatag ttgacttaaa ggaaaaggct tatataaaaa
     6301 attataaaga ttgaaagctc atagaagaaa gggagcaaac ccgttaatcg ttatcacaat
     6361 aaagtaggat aaaatttatt tgaatttgta atagggcaag tgcagatagg gagtaggtac
     6421 atccgtcaga tttttccttt tcagctcccc taattgtaat ctcctaatgc gtccgtaaag
     6481 aatggacgca ttatcgctta tgtaaagggt cttcgttctt cggatataat ggcaaagcca
     6541 agtggataag agtgcgtaat aaagcaatta acgctttaaa cgcactctaa tttattgggc
     6601 tttactcatc atatcaacga atctcttgat agctgtcgct acttacgcca cttgacatta
     6661 atcgatgcgg agattgattg aatggtgacc aaaaaggtca aaaataacac gagagaggtt
     6721 gatctacatg gaaaccattt tagagattgt acgtatcgaa caagttattt gtgaggctga
     6781 ggagggtgtt aattacacga taaaaggtcc aaaagatgga gcggaaattg catctcgttt
     6841 tattggacgt gatgatcgtg aagtattctt tgttatgtgt ttaaacacta agaatcacgt
     6901 tgtcgcagtt catcgttgtc atgttggttc attgaatgct agtatagtac atccgcgtga
     6961 ggtgtttaaa tcagcgatac ttaacaatgc agcaagtatc attgttgcgc atcagcatcc
     7021 aagtggtgac ataacaccat caatggaaga tattaatgtt acaaagagat tagttgaggc
     7081 aggaaagcta ttaggcattg aagtgtttga tcatttagtg gtaaacggtg atagtaaatt
     7141 tacaagttta aaagagaaag ggcattttta aaagggagga atctcccttt ttcttcaagt
     7201 aattacggaa ctaccgaaaa gttacgttct taagctgatt atggtaaaat ggaagcagat
     7261 aatatgcgaa agcttacata taaagggggg gggagaattt gacagaagaa attattaaat
     7321 gtaaaactcg tgtacaaaaa catggggaag tatttactcc taaaagaata gtaaatcaaa
     7381 tgctagatat accagaaata aaagaagcct gtgaaaatct tacgacaaca tttttagagc
     7441 catctgctgg tgaaggtgcg tttttagttg agatacttga gcggaaatta aaaatggtat
     7501 cagagaagta taataaagat ttagttcaat ttgaaaatta ctctttacta gccttaacta
     7561 cattgtatgg aattgaattg ttagaagaca atgcccaaac atgcgtgatg aatatgtttc
     7621 aaaagtatta tgactattat aaagagcaaa ttcaatatca taagggaaaa atgaatcaaa
     7681 aagtattaga tagcgctaaa agaattatct ccctaaatat tggcaatggt aactttttaa
     7741 ctcgtaaggc agtagatggt acgccattga tcttcagtga gtgggaagcc attaatttaa
     7801 gaaaaaatac taaaaatata aaagttcaaa gaacagaata tacatttgat gaaatatatg
     7861 aaaatacaca aaaggaaaat gggaaagccc taagacaacc aaaaactgaa ccagaacaaa
     7921 ttgatatttt tagcttttta gatgaaccaa ttgataaaaa agaagaagtt gtaaaagaaa
     7981 tgcaatacat tcctgtgaaa ataatcgatg tttataaaga ggagatggag gaagccaatg
     8041 gataagacag taattaagcc ttttcaggaa attaaatata aagtgtatgg ttatacctta
     8101 cctgaggttc caaaccacga tggttatgtg aagataggtg atacgacacg tgacgctgtt
     8161 acgagaattt ttgaacaagt aggtacagct ggtttaaatc ctaaaatatt gtttgaaaaa
     8221 ctagctcgta aatctgatgg aaaatggttt cgtgataaag atttacataa atttcttatt
     8281 ctaaatggaa tagagaaaaa gaattttaat agtcgtgctg atgagtggtt ctattttaat
     8341 ggaacgctgg aaaaggctga agagttaacg aataagtata taaaccgtga ttatgatgaa
     8401 atacaaattg atgataaacg ttcagattat gtattaagaa atgaacagca acaagcggta
     8461 gaaaaaacgt atgaatatta tcaaagtaag caggagccaa aagagttttt gtggaatgca
     8521 aaaccgcgtt ttgggaaaac attaacaaca tttgatttta ttagaaacct taatgcaacg
     8581 aatgttttaa tcgtaacaaa tagacctgcg attgctaact catggtttga tgatttccat
     8641 aaatttattg catggcaaga gccacaaatg aagttcgtat cggaaacgga tgcactaaat
     8701 ggaaaagcaa tgactagaga tcagtatctt gaatttattt atacaacttc ccatgttaat
     8761 cccactcaaa ttgcatttat ttcattgcag gacctaaagg gtgcagaatt tgcaggaggt
     8821 atgtataaga aactagaatg ggtagctgga ctaaactggg acttgctcgt aattgatgaa
     8881 gctcatgaag gtatcgatac tagaaaaact gatatagcat ttagccaatt aaaaagggaa
     8941 ttcaccctgc atttatcagg tactccgttt aaagccttag ctaaaggaga tttttctgaa
     9001 gaacaaatat ttaattggtc gtatgtagat gaacaagaag ctaaagaaaa ctgggatcca
     9061 acaattggta gcaatcctta cgaaagctta cctactttga atttatttac gtatcaaatg
     9121 agtaaaatga tagaagatga agtatcagca ggattaacaa tagaggaaga gaaaaacgtt
     9181 gattatgcat tcgatttaaa tgaatttttt agagtgaaag aaaacggaag atttgaatat
     9241 gaagagagtg ttgttcgctt tttagataat ctatcttcag ggaagtttcc attttctgaa
     9301 aatcaatatc gtaatgaact aaatcataca ttttggctgt tacctcgtgt gaatgcagca
     9361 aaagcacttg aaaaattgtt aaatgctcat cctactttta aagattataa agtcgtactt
     9421 gcagcaggag atggtgttag tctgcatgat ggagcagaag cagaagcgct tgatttaaaa
     9481 gaaaatacaa aaagctttga taaagttaga aatgcaattg agcaaaatga taagacgata
     9541 acactttctg tcgggcaact gacaactggt gtgacgattc cagaatggac agctgtattt
     9601 atgctaaata atattgaatc tcctagttta tactttcaag ctgcattcag gtcacaaaac
     9661 ccttatgaat atgaaaaaga tggaaaactt tttaggaaag aaaatgcgta tatctttgat
     9721 ttttcaccag atcgaacatt aaggctttat gatgaatttg ctaacaactt gtctagtggt
     9781 agttctaaaa caagtgaaga aagaaagcgc aaaataaaga agttattaaa tttctttcca
     9841 gtaattgctg aagacgaaga aggtacaatg cacgaaatag atgcatctga agtactaacg
     9901 atacctacac gaattacttc acgagaagtt gttaaaagag gctttatgag taatttacta
     9961 tttgctaata tatcaggtat cttttcagga gattcaccat ttaaagagat tttagataaa
    10021 ataccacctg agaaaaataa aagattagaa aaacctcgtg aggtttctat tactgatccg
    10081 catttaaatg atgaagggga agtagagata ccaaaagaag tagtgttagg taaatcaaaa
    10141 gaacttttcg gagaaaaaat ttattcatca attgaagtgg ttgatgaagt tgtatcatcc
    10201 ttcgaagaag ctgaagaaaa acaaaaagaa tctattaaaa aacttgcgaa agatataaca
    10261 gcatcatttt cagatggatt taataactta aaggaatcct tcaaactgaa caaaggacaa
    10321 accgaaaagc taaaagagtc agtaaacaat tcaattgagg atattataac tgagaaaagt
    10381 ttaacactaa gcaatcaagt taaagagata gaggaagaat atacaaagaa aaagcaagaa
    10441 gcagaaaaga aaaatgatga aacagaatta aaagcagcga ttcagcaata tgaagaagaa
    10501 aaacaaaaga tagaagagtc ttttgccgat gatattaata aagaagtaga aaacacaatc
    10561 aacactgctg tcgaagaaca aatagaaaaa gtagaagaaa agaaaaagaa aacaacagaa
    10621 gatgatgttc gagatcactt acgaggattt gcacgtacaa tacctgcatt cctaatggca
    10681 tacggagata atcagactag attagaaaac tttgaagaga atattgatga agctaccttt
    10741 gaagatatta caagtatcac aattgaagag ttcaagaagc ttcgcgatgg ttttgaatat
    10801 gaggacgata atggtaatag aaaagtcatt catggtttat tcaatgaggt agtttttaat
    10861 gccagtatac gagagttttt agatactaaa aagcgtttag cgaattactt tgatgaaagt
    10921 ttagaagagg atatttttga ctatattcct ccacagaaaa cgaatcagat ttttacgccc
    10981 aaaagagtag taaaaaaaat ggtcgataaa ttagaagaag aaaatcctgg gattttttct
    11041 gataggacga aaaggttcgc cgacttgtat gcgaaaagtg gtttatatat tacggagata
    11101 gtaaagaaat taaatgaagg tttgaaagga caaattccaa atcaacagga acgtattaaa
    11161 tggatacttg aaaatcaagt atatgcgtgt gcacctagta atattatttg taacattgtt
    11221 aaaaactttg tctatagtca tacgataaat gtgtcaacca aaaatcttat agaagttgat
    11281 acaatgaagt tagcaagtga agagaagtta agtactgaaa tctatgagtt atttggagat
    11341 gatagattga aatttgatgt aattattggt aatcctcctt accaagatga aacgatagga
    11401 gaaaataaaa cgtatgctcc accaatttac cacaagtttt tggaggagtc ttataaacta
    11461 gctgataaag ttgaaatgat tcatcctgct cgatttttat tcgatgctgg tagtacacca
    11521 aaagcatgga atagaaaaat gttagccgat gaaaatttga aggttattga ctatgtggat
    11581 gatagctcaa aagtatttcc taacaccgat attaaagggg gtatagcgat aacctaccgt
    11641 gatgctcaaa agagaatagg tccgatcggg acctttacaa agtatccaga attaaatact
    11701 atccttcgta aagtgaagat ggataatttt aattcaattg ataaaattat ttattcagca
    11761 gatagctata agtttacaca agcattacac gacgattatc ctgatgcaga ggcacgatta
    11821 agcaaaggtc atgcatttga tgttcgctct aatgtatttg atagcattgg acatatattt
    11881 aaaaatgaaa agccctcaga taatagtgaa tatattagga ttataggtag acaaaatcat
    11941 aaaagaatag aaaaatgggt gaaacgtgat tatattggtg aacacccaaa tttagataaa
    12001 tatagtgttc ttctaccagg atcaaatgga aatggtgact ttggagaaac atttgcttct
    12061 cctataataa aagaagctgc tgttgcacac acacaaacgt ttattagtat tggtcatttt
    12121 gacaatataa tagaagctca aaacctgtta aaatatgtaa aaacaaagtt tgcgcgagca
    12181 atgttaggaa tattaaaagc aactcaagct aatagtcgac caaaatggaa gtgggttcca
    12241 atgcaaaact ttactaatga atcagatatt gattggtcgg aatcaatatc tgaaattgat
    12301 aaacaactat ataaaaaata taatttgaac cagaatgaaa ttcagtttat tgaagataaa
    12361 gtaaaaccaa tggaataaaa tataagcaag acattgttgt attcaaccag catctatggt
    12421 tcaaattggt gcaagtaatg tcaatttcaa tcctttttca tacattttca tccatataat
    12481 aattcccaaa acggtgatat aaatggattg cgatatattc aatagactta gaattaatct
    12541 gtatatttct caaaacgtta atcgttgtta tatcaaggat ttcacggcat catccgtttg
    12601 gatggtgtct tttttgggtt gaattccttg aaaattgggt ctattttaca gacccttttc
    12661 tatataaact gttttcgata cttggaaaaa tctgttgttt ttaaattt
//
LOCUS       DADVXM010000071        12290 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.075, whole genome shotgun sequence.
ACCESSION   DADVXM010000071 DADVXM010000000
VERSION     DADVXM010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.075"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..382
                     /locus_tag="KB927_002106"
     CDS             <1..382
                     /locus_tag="KB927_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBB6841011.1"
                     /translation="HQRSLNLTPFTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLP
                     KFAFVLVLSLTFEIIQFIFAIGATDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRV
                     IIFVGILLLVLLLVYRTHLRINYV"
     gene            696..3683
                     /locus_tag="KB927_002107"
     CDS             696..3683
                     /locus_tag="KB927_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HBB6841012.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMSSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMASADGIRYITPQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSL
                     YLLEGFLNQPSELTPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDAN
                     AHYGELDTLSQNSINMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGK
                     AITEYGKVYKTKHQLRYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYD
                     GMEEQLNALGLVTNAIIYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVG
                     KYTFRYEAELSNGKLRPLNVEEF"
     gene            3920..4144
                     /locus_tag="KB927_002108"
     CDS             3920..4144
                     /locus_tag="KB927_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6841013.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            4159..5028
                     /locus_tag="KB927_002109"
     CDS             4159..5028
                     /locus_tag="KB927_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBB6841014.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5009..5743
                     /locus_tag="KB927_002110"
     CDS             5009..5743
                     /locus_tag="KB927_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6841015.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            5776..6639
                     /locus_tag="KB927_002111"
     CDS             5776..6639
                     /locus_tag="KB927_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003109014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBB6841016.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHLNQILRFELLRMMSWKVGIKTEFSLSVGKNYKYINKYID
                     EDLWNRLLSTYRMDSYENIWKSLFICHQLFREVSKEVAELLGFDYPEYGKNITRYTED
                     MYKKYVENDYF"
     gene            6683..7210
                     /locus_tag="KB927_002112"
     CDS             6683..7210
                     /locus_tag="KB927_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBB6841017.1"
                     /translation="MESTDVINEIRGILPRNSIGKYDLLTIFTHKTVFDKIVKVLSLD
                     FQNKVDYVAAPEAIGWILGTAIAKELGVGFIGVRKGDKLPYAKEEIISTHFTDYSGQD
                     KSFEISKSSIVRNKRVLIVDDWIETGSQMKALIALLEKLDCSIIGLATIGIDINEVTQ
                     KWIDSSFVAYIGSNI"
     gene            7438..8757
                     /locus_tag="KB927_002113"
     CDS             7438..8757
                     /locus_tag="KB927_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSsu5 family transposase"
                     /protein_id="HBB6841018.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGRLSSDSGLVLVKELMNTFGFSH
                     LAKQWLHITDHRAYFTHDNLAILEQLIMQLIAGYSADSSANLLRRDPVFQAVLGKKQL
                     ASQSSISRFLDRFTEENIDQLQALNQSLIDKARLIRNDTELIIDVDSTHSDTFGRQEQ
                     TDYNAHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKAFINPLLHHYKSTLPH
                     TEILVRGDSGFATPEVYESCEATESQYVIRLKSNRRLSQLAEHSVLYGDNQEWEEREV
                     QYFSLPYQAQSWSKPRRVCIRSVREGGELLFHHAFIVTNLSDNVSPEVIFSLYGKRGT
                     MENFIKEAKGGFYFDKTDSPRFLENHVRMMISVLAYNLVNFLKSIGFDKVNQGMTIHS
                     IRLILLKVAGKLVQTGRQVYLKLSSYHVYQTEFYKVFERLRRSKQWI"
     gene            8948..10435
                     /locus_tag="KB927_002114"
     CDS             8948..10435
                     /locus_tag="KB927_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HBB6841019.1"
                     /translation="MNYSGFFEVEASIKVNQGSFKGVLSPTQRFKSQEELLSFVSSKQ
                     AKIGNQEGIIADVQTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYEAKL
                     LSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHHAII
                     PTKQVPTESALAKMDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKVADLLFQSIGK
                     TPKQEGWKILFKQQTKEEKEDVQTLPLVIIGEHAEVDVKSAEKETQPPKAFTEGTLLT
                     AMKTANKTVDDEEAIKILQEVEGIGTEATRASIIEALKQKEYIQVIKNKLVVTEKGKL
                     LCQAVESQHLLTSAEMTAKWETYLKKIGKREGNQENFINNIKKFIVHLLEAVPNDIEK
                     LNFSDYQEQKEKEAEKSIVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFRKKKLT
                     KTNVKELLEGKETLVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            10555..10794
                     /locus_tag="KB927_002115"
     CDS             10555..10794
                     /locus_tag="KB927_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBB6841020.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDMMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            10843..10926
                     /locus_tag="KB927_002116"
     CDS             10843..10926
                     /locus_tag="KB927_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBB6841021.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            11051..11395
                     /locus_tag="KB927_002117"
                     /pseudo
     CDS             11051..11395
                     /locus_tag="KB927_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            11498..>12290
                     /locus_tag="KB927_002118"
     CDS             11498..>12290
                     /locus_tag="KB927_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HBB6841022.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFT"
BASE COUNT         4349 a         1961 c         2362 g         3618 t
ORIGIN      
        1 tcatcaaaga agtcttaact tgactccatt tactgctact gggaatttca gagagatgat
       61 agataatgtt ataatcttta ttccatttgg cttgcttttg aatgtcaatt ttaaagaaat
      121 cggattttta cctaagtttg cttttgtact ggttttaagt cttacttttg aaataattca
      181 atttatcttc gctattggag cgacagacat aacagatgta attacaaata ctgttggagg
      241 ctttcttgga ctgaaattat atggtttaag caataagcat atgaatcaaa aaaaattaga
      301 cagagttatt atttttgtag gtatactttt gctcgtatta ttgctcgttt accgtaccca
      361 tttaagaata aattacgtgt aagatgtcta aatcaagcaa tctgatcttt catacacata
      421 aagatattga atgaattgga ttagatggaa aacgggatgt ggggaaactc gcccgtaggt
      481 gtgaagtgag gggaaaaccg gtgataaagt aaaaagctta cctaacacta tagtaacaaa
      541 gaaagcccaa ttatcaattt tagtgctgag gaattggtct ctttaataaa tttccttaac
      601 gttgtaaatc cgcattttcc tgacggtacc cctatcatag catttttaaa aataaatttt
      661 atgtagactt aaaatttact tcatggaggg tttaaatgga tgaaatcaaa agtaacaaaa
      721 aagcatttgg catttattta ggagaaccta gtacagaaca attaaaccaa tttttttatt
      781 tgcatgaaaa agatttagaa ttgatggaga ctatacgacg accagctact agattaggtt
      841 ttgcactaca gttagtctca ctacgttttt taggaacttt tatattagat cttaccaata
      901 ttccccaaaa tgtattgagt tatgtagcaa ctcaactaaa tattgatcct ggagaaatta
      961 tctactatag caggagacag accaggtatc agcacacaaa attgataaaa tcacattatg
     1021 gatatcaaga tttcaaccaa ccggaaatag aaacatacct agctaactgg cttttaaata
     1081 gagcgctgta tacaacagaa tcttcagata tgttgtttga tatgcttcta aaaaaatgtc
     1141 tggatgaaaa gattgtttta cctggaatta ctactttttc tcgttttgtt gctagtgcaa
     1201 ttgaaaaagc tgaagagcat ttataccgac aattgtcttt ggttccaact gaagatgaga
     1261 gaaagcggct tctcaatcat ttagaattaa ttggaactcc agtttatggg gcaataatca
     1321 aaatggacat tttgagaacc ccgttagctg acgatagtca taaagaaata gccagaggtt
     1381 ttgaccgact aaagcaattt caagctttct ctactgaaaa atggaagatg gaatctattc
     1441 ctgaagggaa aataaaagtt cttgcaaatt atgcatttaa agctaaagct caattaattc
     1501 aacgaatgag tgaacagaaa aaactggcgt tgttagtggc atttattttc atatacaaac
     1561 gtaaggctat ggatgaacaa attttagcac tatctaattt ttttgaaact gtttttagac
     1621 gcgccaaaaa taaggaatct aaagaacgtc ttcgtaccat aaaagatcta gatcgagccg
     1681 catcgacact ttcagatatt gtagatttag taatgtccag tcattctgat actaatgaac
     1741 tatcccttcg cgatcgtatc ttagaaaaat attctgagga aaatgttacc gaagctgtat
     1801 cgcaagttcg gctattggtt aaaaatgatc gtgaaccaat agccatttct gaacttctga
     1861 acacttatcg aaagttcaga aaatttattc cggatatttt aactacacta acatttgaca
     1921 gcaatgacta cggtaacaac tgtaaggaac tctggacctt cattaataat agatttccta
     1981 agccgattac ttacaaaatg tttggagcta ttaaacatac tcttccaaag aaatggattt
     2041 attacattca tgaataccct gaacaaacta ataaatgtgt attgattgca gctgtcgaat
     2101 tgttaattca atctttaaaa cgccatgata tttatattcc tcagagtgtc ttatataaca
     2161 atcctatgga ttgcttgatt gatgagaaaa cttgggttca acaaaaatac gttttattag
     2221 aacaactaga tcttccttct tcagcaaatg aaatgtcttt atggttaaag aacgatttgg
     2281 aactgtctta taaagaagcg ctaaatcgtt ggcctacttc taaaatggcc agaatagaaa
     2341 atgcagatcg cctggttgtc tctagactta aaaagacata tgaaaaaaag gaagataagt
     2401 cttttagacg tcgcattcag cagttacttc ctaaaattga tttgtcagat ttgttattgg
     2461 aagtaaacca acagttaaat cttactcaat catttaacca cttaagtgac aaggacacca
     2521 aaatgaaaga cttggatatt agtttattag cagttctttt atcagagtcc tgcaatattg
     2581 gtttttcccc ggtttcaaaa gaaggatttg attctttaaa gtatgatcgt cttgtctatg
     2641 tcaatcatca ttatattcga gtggatacac tttcaggagc taatcaaaaa ataatacatg
     2701 cacacaggaa acttgccacc tctaagatat ggggtgatgg gcatatggct tcagctgacg
     2761 gtattcgtta tatcacacca caacgttccc tatattctag aagtaatcca aaatattttg
     2821 gccgtggtcg tgggatcaca ttctacaatt ttgtctctga tcaatatata gggttccacg
     2881 gaatggtcgt ttcagggaca ctgcgagatt cgctttacct tctagaagga ttcctcaatc
     2941 aacccagcga attaactcct aatcagatca tgactgatac agctggttat agcgatatga
     3001 tttttggtct ctttggctta ttagggtttc aatttagtcc aagaattgcc aatgataaag
     3061 gaaccaaact ttggcgaatc gacgctaacg ctcactacgg ggaacttgat acgttgtctc
     3121 aaaattcaat taatatggaa ctgatttata cccattggga ggacattctt agggttgcag
     3181 gttcgttgaa atctggaaaa gtgaatgcaa cagaattaac gaaatctctt caacggaatg
     3241 ggcaacccac gcctttagga aaagcaataa ctgagtatgg aaaagtttat aagacgaaac
     3301 atcagcttcg ttatatttct gacgaaatat atgcacggca aattttagaa caattgaata
     3361 agggggaagc tcggcatgcc ttatgccgta atatttttta tggacgaaaa ggaaaactct
     3421 accagactta ttatgatggg atggaagagc agctcaatgc attaggatta gttactaatg
     3481 ccatcatata ttggaactca ctgtatttag aaaaagtatt tgaacaaatg aaagctgaag
     3541 gattcgactg ttccgaagaa atgatacgca ggcaatctcc actaattagt gatcacatca
     3601 attttgttgg taagtatacg tttagatacg aagctgaatt atccaacggt aagttacgtc
     3661 cattgaatgt agaagaattc tagcaatgtt cgggttttgc atgctaccgc actatttcgt
     3721 atgactgttc cagcgaatca cttcgaatag aaaaagagaa aaacacgaga acagcgttaa
     3781 atcaacgttt cttgtgtttt tacttttgtg ctaccgcact atttcgtttc tatgttccat
     3841 gtaccccata ttttaataac tattgtgttt atcaaccaaa tggtttataa tattcttagc
     3901 gtaaacttgg aggtgctgta tgactacggc agaaatgatt aaagaactgt gtgagcaaat
     3961 gaatataagt gtttccgaac ttgctagacg tattggccag actccacaga atttcaataa
     4021 aaaattacaa cgagaaacag taaccttgga tgagttgaag gccattgctg atgtgctagg
     4081 tgtcaagttt gtgcaggcat ttattttacc agatggagaa gaaataaaaa tatctaacga
     4141 ataaaggagg atgtttatat ggtaggtaat gttattcaaa tagtaacaga gaaattatca
     4201 tctttgcctt ttatagaagg catcgtatta gggggctcac gtgcaagagg cacccataca
     4261 gaaaattctg atatagatat cggaatctat tacaattcag actcatttga cctgacagcg
     4321 attaatcaaa ttgctacaga attggatgat aaaaatagaa acaaccttgt tgtgcctccc
     4381 ggagcgtggg gtgattggat taatggcggc ggatggttat ttataaatgg gtatcatgtt
     4441 gacttgattt tacgtgatat aaaacgggta gaacaaataa tcaaagatac ggagcaagga
     4501 attgttactg ccaattatca gaccgggcat ccccatggtt atataagtgc aatgtatcgt
     4561 ggagaattag cgattagtaa aatactatat gctaagaacg aaagcttatg cgaattaaaa
     4621 aagcaggcag aaatttaccc tactgctcta aagaaaagct tgatgaactt ttttatattt
     4681 gaagctgaat tctctttaat gtttgtaaaa gcaaatgcgg gggtagagga taaatattat
     4741 attgcaggcc atgtttttcg tattatttca tgcttaaatc aagtactatt tgcatgtaat
     4801 aatgcttatt gcattaacga aaagaaagct ataaaactgc ttgaaacttt tgaatataaa
     4861 cctgaaaaat atgccgaaag agttaatcat atttttgaag tactcggtct ttctcttttt
     4921 gaatgctacg atatgaccga gaaactttat aaagaagtga atgaaattgt atcggagata
     4981 aataactttt taaacgagga gagttcagat gaaagaaaac aaatatgatg ataatatatt
     5041 ttttcaaaaa tacagtcaaa tgagtcgctc gcagaaagga ctggctggtg cgggagaatg
     5101 ggagactttg aaaaagatgc tacctgattt taagggtaag cgtgtgcttg atttaggatg
     5161 cggctatgga tggcactgta tatatgcgat ggaaaacggt gcttcctctg tagtaggtgt
     5221 tgatatttct cataaaatgc tcgaagtagc aaaaggaaaa acccattttc cacagattga
     5281 atatgaatgc tgtgccatag aagatgtgga tttcccagag gagagctttg atgtaatact
     5341 aagttcgctt gcgtttcatt atgtagcaga ctatgagaat ttaataaaaa agatatatag
     5401 gatgctgaag gctggtggca atttagtttt tacagttgaa catcctgttt ttactgctca
     5461 tggaacacaa gactggtatt ataacgaaaa aggagaaata ctgcatttcc cggtggacaa
     5521 ttattattat gagggcaaac ggacagctat gtttttggaa gaaaaggtta caaaatatca
     5581 tagaacactg accacatatc taaatacact gctttcaaat agttttataa taaatcagat
     5641 tgtggagcca cagccgccag agaacatgat ggatattccg gggatggcgg atgaaatgcg
     5701 acgcccaatg atgctgattg tatcggcaaa aaagaagatg taataatata gaaaaaataa
     5761 acgaggagta tgtaaatgag atcagaaaaa gaaatgatgg atttagtact ttctttagca
     5821 gaacaggatg aacgtattcg aattgtgacc cttgaggggt cacgcgcaaa tattaatata
     5881 cctaaagatg aatttcagga ttatgatatt acatattttg taagtgatat agaaccgttt
     5941 atatctaatg atgactggct taatcaattt gggaatataa taatgatgca aaagccggag
     6001 gatatggaat tattcccacc tgaagaaaag ggattttcct atcttatgct atttgatgat
     6061 tacaataaaa ttgatcttac cttattgccc ttggaagagt tagataatta cctaaagggc
     6121 gataaattaa taaaggttct aattgataaa gattgtagaa ttaaaaggga catagttccg
     6181 actgatatag attatcatgt aagaaagcca agcgcaaggg agtatgatga ttgctgcaat
     6241 gaattttgga atgtaacacc ttatgttatt aaaggattgt gccgcaaaga gatactgttt
     6301 gcaatcgatc atctgaacca gattctacgg tttgaactac ttaggatgat gtcgtggaag
     6361 gttgggataa agacagaatt ttcattaagt gttgggaaaa attataagta tattaacaaa
     6421 tacattgatg aagatctatg gaatagatta ttatctacat atcgcatgga ttcctatgaa
     6481 aatatttgga agtcattatt tatatgccac caattgttca gggaagtgtc caaagaggta
     6541 gcagaactac tggggtttga ttatccagag tatggtaaga acataacaag atataccgag
     6601 gacatgtata aaaaatatgt tgaaaatgac tatttttaaa gattagcaaa gattattaac
     6661 cataagcaag gggtgtaaat gtatggaaag tactgatgtt ataaatgaaa ttagaggtat
     6721 attacctcgt aactcaattg gaaaatatga tttactaact atttttacac ataaaaccgt
     6781 ttttgataaa attgtaaaag tactatcatt ggattttcaa aataaagtag attatgtggc
     6841 tgccccagaa gcaattggat ggatactagg cactgccata gccaaagaac ttggagtggg
     6901 gtttattgga gtaagaaaag gtgataagct gccatacgca aaagaagaga ttatttcgac
     6961 acattttacc gactattcag gtcaagataa aagctttgaa atatctaaga gttctattgt
     7021 gaggaacaaa agagttttga ttgtagatga ttggatagag acaggttctc aaatgaaggc
     7081 tttaatagct ttgttagaga aattggattg cagcattatt gggttggcta ctattgggat
     7141 tgatataaat gaggttactc aaaaatggat agacagcagt tttgtagctt atattggctc
     7201 aaacatataa taaaccgaaa gaaaatcttg aatcaaaatt ttggatggcg ttaatttaca
     7261 atacaacgaa agatgtttac cctgaataat tcatactttt taattgaaac cgtctgaaac
     7321 tgcctaacgg cagtctgata attacttttt tagtttcacc ccttaagtga tgaaaaaaga
     7381 accccattct gctatggtaa aggtgacgaa accaaccata agaaaggagt tcttctcatg
     7441 actagcttac acaaaaatca agttaaattc aattcaaata tcactatttc acataccggt
     7501 ggtcgtctat caagtgattc ggggttagtc ctggttaaag aattaatgaa taccttcggc
     7561 ttttcgcact tagctaaaca atggctccat attacagatc atcgggctta ttttacccat
     7621 gataacttag cgatattgga acagcttatt atgcaattaa ttgctggtta ctcggcagac
     7681 tcatcagcta atctattaag acgggatcct gtctttcaag ctgtactcgg taaaaaacag
     7741 ttggcatcac aatcctcaat ctcacggttt ctggatcgtt tcaccgagga gaacatcgat
     7801 caactccaag cattaaatca gtcattgatt gataaagcac gtttaattcg caatgacacc
     7861 gagttaatca ttgatgtcga ttccacacat tcggatacct ttggacgcca agaacaaaca
     7921 gattataatg cccattatca aacctacggc tatcacccat tagttgcctt tgatggactg
     7981 accggagatt tcttaaaagc tgaactgcgt tcaggcaatc agtacacatc taaaggggta
     8041 aaagccttta tcaacccgct tttacaccac tacaagagca cgttacctca taccgagata
     8101 ttggttcggg gtgacagcgg cttcgccaca ccagaggtgt atgagtcttg tgaagcaact
     8161 gaaagccagt acgttatccg attaaagagc aatcggaggt taagtcagtt agctgaacat
     8221 tctgttcttt acggggacaa tcaagaatgg gaagagcgag aagtgcagta tttttcacta
     8281 ccttatcaag cacaatcctg gtcgaaacct cgtcgtgtct gtatacgctc cgtccgtgaa
     8341 ggaggagaat tgctatttca tcatgcgttt attgtgacta atctatccga caatgtctcg
     8401 cctgaagtca tattttctct ttacggcaag cgaggaacaa tggaaaattt catcaaagaa
     8461 gcgaaaggtg gcttttactt cgataaaaca gatagcccgc gtttcttaga aaatcatgtc
     8521 agaatgatga tcagtgtcct tgcatacaac ctcgttaatt ttttaaaaag cattggtttt
     8581 gataaagtga accagggcat gacgattcat tccatccggc tgatattgct taaagtagcc
     8641 ggtaaacttg ttcagactgg gagacaggtc tatctcaaac tgtcaagtta tcatgtgtat
     8701 caaactgaat tttataaggt ttttgaacgc ctgcggcgat ccaaacaatg gatttagact
     8761 agttatcaca caaatttttt aaccgattct ttttcaaggg attcgtctgc ccttaaatag
     8821 acaaataatt tttattatga tcttcttccg taggcatcct gttcgaaaac acattatttt
     8881 ggaagaaagt atctgcctaa tttaaaaatt ggcaatttgt tcaaaaaaac aggttaaatt
     8941 tagagctatg aattattcag gttttttcga ggtggaagct agtataaaag taaaccaagg
     9001 gtcgtttaag ggcgttctaa gccccacaca gcgttttaag agccaagagg aacttttatc
     9061 ctttgtttct tctaaacaag ctaaaatagg caatcaagag gggataattg ctgatgttca
     9121 aaccaaagag aagaaaacga atagtccgag tttgttttct ttaagtagtt tacaatcaaa
     9181 agtcaatcag ctttataaag cgacagcgag ccaaacttta aaagctatgc aaggactgta
     9241 tgaagcaaaa ttattgagtt atccaagaac agatacacca tttattacag agaacgaatt
     9301 tgcttattta aaagcaaatt ttggcaaata tagcggtttt ttaggacttg atctcgaaat
     9361 ggttcaaaca gagcctagaa agcgttatgt ggacggtagt aaggtacagg aacaccacgc
     9421 cattatccca acaaaacaag tacctaccga atctgcatta gcaaaaatgg acgatttaca
     9481 acgaaaaata tatgctttag tcgttaaaac gaccgttgcc atgtttttac ctgattactt
     9541 gtatgaagaa accaagatac aaacgaaagt agctgatttg ctgtttcaat cgatcggaaa
     9601 gacaccaaaa caagaaggtt ggaaaattct tttcaaacaa caaaccaaag aagaaaaaga
     9661 ggacgttcaa acgttaccct tggttatcat tggcgaacat gccgaggttg acgttaagag
     9721 tgccgaaaaa gaaacacaac caccgaaagc ttttacagag ggtacattat taactgctat
     9781 gaaaaccgct aataaaacgg ttgatgatga agaagcaatc aagattttac aagaagtcga
     9841 ggggatcgga acagaagcga caagagcaag tattattgaa gcgttaaaac aaaaagaata
     9901 tatccaagtg attaagaata agcttgttgt aactgaaaaa ggaaaattat tgtgccaggc
     9961 agttgaaagt cagcaccttt taacgagtgc tgaaatgacg gctaaatggg aaacgtattt
    10021 aaaaaaaatc ggtaaaagag aaggcaatca agaaaacttt attaataata tcaagaagtt
    10081 tatcgttcat ttactggaag ctgtacctaa cgatatagaa aaactaaatt tttctgatta
    10141 ccaggaacag aaagaaaaag aagctgaaaa aagtattgta ggaaaatgtc ctaagtgtgg
    10201 caacaatatt gtattaaaaa aatcgtttta tggttgttca aattatcctg aatgtaagtt
    10261 tactttagct gaacatttta gaaagaaaaa actaaccaaa acgaatgtaa aagaattact
    10321 ggagggaaaa gaaaccctgg taaaaggaat caaaaacaaa gagaaaaagc cctacaatgc
    10381 cgttgtaaaa atcggagaaa agggatatat tgattttatc tctttctcaa aataaacata
    10441 aaagcccttt aaacagggct tttatatatt aatcacaaat cacctatcac aaatcacaaa
    10501 tcacttgcga tttgtgatga taaaataaga gtaagaagaa atagaaagaa gtgagtgatt
    10561 gtgggaaatt taggcgcaca aaaagcaaaa cgaaatgata caccaatcag tgcaaaaaaa
    10621 gatatgatgg gagataagac ggttcgtgtt cgtgctgact tgcaccatat cataaaaatc
    10681 gaaacagcaa agaatggcgg aaacgtaaaa gaagttatgg aaataagact tagaagcaaa
    10741 cttaagagtg tgttgatagt gcattatctt aaaattttgt ataataggaa ttgaagttaa
    10801 attagatgct aaaaatttgt aattaagaag gagggattcg tcatgttggt attccaaatg
    10861 cgtaatgtag ataaaacatc tactgttttg aaacagacta aaaacagtga ttacgcagat
    10921 aaataaatac gttagattaa ttcctaccag tgactaatct tatgactttt taaacagata
    10981 actaaaatta caaacaaatc gtttaacttc tgtatttatt tatagatgta atcacttcag
    11041 gagtgattac atgaacaaaa atataaaata ttctcaaaac tttttaacga gtgaaaaagt
    11101 actcaaccaa ataataaaac aattgaattt aaaagaaacc gataccgttt acgaaattgg
    11161 aacaggtaaa gggcatttaa cgacgaaact ggctaaaata agtaaacagg taacgtctat
    11221 tgaattagac agtcatctat tcaacttatc gtcagaaaaa ttaaaactga acattcgtgt
    11281 cactttaatt caccaagata ttctacagtt tcaattccct aacaaacaga ggtataaaat
    11341 tgttgggaat attccttacc atttaagcac acaaattatt aaaaaagtgg tttttggata
    11401 aagtccgtat aattgtgtaa aagtaaaaag gccatataac agtcctttta cggtacaatg
    11461 tttttaacga caaaaacata cccaggagga cttttacatg acccaagtac attttacact
    11521 gaaaagcgaa gagattcaaa gcattattga atattctgta aaggatgacg tttctaaaaa
    11581 tattttaaca acggtattta atcaactaat ggaaaatcaa cgaacagaat atattcaagc
    11641 aaaagaatat gaacgaacag aaaaccgaca aagtcaacga aatggctatt atgagcgcag
    11701 ctttacgaca cgtgtaggca cgctagaatt aaaagtaccc agaacacgtg atggccattt
    11761 ttcacccaca gtgtttgaac gttatcaacg aaacgaaaaa gccctcatgg cttcaatgtt
    11821 ggaaatgtat gtatcaggcg tttcaactcg taaagtatca aaaattgtgg aagaactttg
    11881 tggtaaatcc gtctctaagt ccttcgtttc tagcttaaca gaacagctag aacctatggt
    11941 taacgagtgg cagaatcgtt tattatcaga aaaaaattat ccttacttaa tgaccgatgt
    12001 actctatata aaagtacgag aagaaaatcg agtactctca aaaagctgtc atatagcgat
    12061 tggaataacc aaagatggcg accgtgaaat tatcggcttc atgattcaaa gtggcgaaag
    12121 cgaagagacc tggacaacat tttttgaata cctaaaagaa cgcggtttac aaggtacgga
    12181 actcgttatt tctgatgcgc acaaaggatt agtctctgcc attagaaaat ccttcaccaa
    12241 cgtaagttgg caaagatgcc aagttcactt cctaagaaat atctttacca
//
LOCUS       DADVXM010000072        12278 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.076, whole genome shotgun sequence.
ACCESSION   DADVXM010000072 DADVXM010000000
VERSION     DADVXM010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.076"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            116..709
                     /locus_tag="KB927_002119"
     CDS             116..709
                     /locus_tag="KB927_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6841023.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKEAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDEYAIQPHYTNKENFDLGITETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            725..1624
                     /locus_tag="KB927_002120"
     CDS             725..1624
                     /locus_tag="KB927_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBB6841024.1"
                     /translation="MTPTQFKAKTRNFATEKHLNPQIVQRYYMMEKLLERIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTADPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERINEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKVERKQNFKRSQQMNQEMER"
     gene            1627..2112
                     /gene="ssb"
                     /locus_tag="KB927_002121"
     CDS             1627..2112
                     /gene="ssb"
                     /locus_tag="KB927_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBB6841025.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFANQNGNR
                     EADFINCVIWRKPAETMATLAKKGGLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTATFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            2157..2390
                     /locus_tag="KB927_002122"
     CDS             2157..2390
                     /locus_tag="KB927_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841026.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGRDNSFWRLTKVTIAATAVILTAILPLYM"
     gene            complement(2549..2671)
                     /locus_tag="KB927_002123"
     CDS             complement(2549..2671)
                     /locus_tag="KB927_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBB6841027.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            2826..3086
                     /locus_tag="KB927_002124"
     CDS             2826..3086
                     /locus_tag="KB927_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841028.1"
                     /translation="MDKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            3529..3735
                     /locus_tag="KB927_002125"
     CDS             3529..3735
                     /locus_tag="KB927_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBB6841029.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     QTCGKKYTLSYGDYVLIDEKGKKH"
     gene            3735..3986
                     /locus_tag="KB927_002126"
     CDS             3735..3986
                     /locus_tag="KB927_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841030.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            4002..4439
                     /locus_tag="KB927_002127"
     CDS             4002..4439
                     /locus_tag="KB927_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841031.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            4884..5063
                     /locus_tag="KB927_002128"
     CDS             4884..5063
                     /locus_tag="KB927_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841032.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQKLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            5404..5667
                     /locus_tag="KB927_002129"
     CDS             5404..5667
                     /locus_tag="KB927_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBB6841033.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            5661..6011
                     /locus_tag="KB927_002130"
     CDS             5661..6011
                     /locus_tag="KB927_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6841034.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(6035..6649)
                     /locus_tag="KB927_002131"
     CDS             complement(6035..6649)
                     /locus_tag="KB927_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6841035.1"
                     /translation="MRVAYIRVSSIDQNEQRQVEEMKKFGAERIFIEKQSGATITHRP
                     VFQEVLDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSTVNHE"
     gene            complement(7343..8338)
                     /locus_tag="KB927_002132"
     CDS             complement(7343..8338)
                     /locus_tag="KB927_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6841036.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKNN"
     gene            complement(8433..9305)
                     /locus_tag="KB927_002133"
     CDS             complement(8433..9305)
                     /locus_tag="KB927_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6841037.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNKLLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            complement(9318..10745)
                     /locus_tag="KB927_002134"
     CDS             complement(9318..10745)
                     /locus_tag="KB927_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBB6841038.1"
                     /translation="MTKKAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPGDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDRLYMKPVRELEQLRVG
                     SGVETTVNLAGEIIIAQDASFKEALIDVLLTKSKNQEIKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            complement(10799..12073)
                     /locus_tag="KB927_002135"
     CDS             complement(10799..12073)
                     /locus_tag="KB927_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6841039.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLGVTIMCVRIGLCGFASTPLSVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
BASE COUNT         4177 a         2165 c         2066 g         3870 t
ORIGIN      
        1 aaccagcagc ggattcaaaa agaaattgaa ttagatcgat aaatttcttt cttgttaata
       61 taaaactaac atgttatagt tatgttagtt ttatattaac tttaggggaa aagcaatgaa
      121 agacaaaatc cagtgtattt ttgataaaca taatgggaat ctatccttga aggatgctag
      181 aagtgaagga ttatcgccta tgacgttaga tcgattagcc gaaaaggaca aaatagaaaa
      241 ggtagcacca ggtttctata ccttaaaaga agcgttcgtg gatgaattgt atctcgctca
      301 aagtatctat tccagaggga ttttttctca tgagactgcg ctcgatcttt ttcaagtagg
      361 aacgtatatc cctaaaaaga tcaatatgat gtttcctaaa ggatacaatg tttcaaagga
      421 gaaattagac gagtatgcta ttcaaccgca ttacacgaat aaagaaaatt ttgacctggg
      481 aatcacagaa acagaaagct tttacggcaa taaaatttta gtctatgatt tagagcgaac
      541 gttatgtgac atgtggaatc caagatacaa agcaagcgta gaggtaaaac aagaagcatt
      601 aaaagaatat atgacaagta ccagtagaaa tacaaataag ctaagaagat acatggatat
      661 tttaaaatca ccaaaagaaa tgactttgta tatgttgcca ctttattgag aggagtaaag
      721 gtgaatgaca ccgacgcaat ttaaagcaaa aacgagaaat tttgcaacag agaaacattt
      781 aaacccacaa attgtccaaa gatattatat gatggaaaaa ttattagaac gtattgttga
      841 atcgccttat catgatgatt ttgtattaaa agggggattt ctgatcggat caaaatacgg
      901 gttagaaaac cgttcaactg ttgatattga tacgacttat cgaaattcga aactaacaaa
      961 agaaaagtta gaaactgttt tttctgaatt aacagctgat cccacaaaag atggaattcg
     1021 atttgaatta aagggattaa cagagacgag ggaagctgat tattacccag gttttcaagc
     1081 aaagtttatt gcttatcttg agaatgcacg tgtaccattt aaattagata ttacttcagg
     1141 tgattctatt attccagcgg cattgatgta tgaacacaaa ttaatgtttg aagataaaac
     1201 gattcatatt ccagcttatc ctacggaaca aattctagct gaaaaattac atgccacgtt
     1261 tagttttgga aaagataatt cgcgcatgaa agatttttat gacctgtata tgattccgaa
     1321 attagaacgt atcaatgaga aaaatttgta taaaagtgtt caaggaacat tcaaggaaag
     1381 aaataatcaa tcggtgttta agcatttgta tgaccaggaa atgcctcaat tggtgaagga
     1441 tgaggggttg agggaaaagt ggaaaagata ccaacaagaa aactattttg ccaaagacat
     1501 ttctttcgaa tctacactaa cttccgttga ttccctgatg caatcaattg tagagcaaga
     1561 gaaggtagaa cgaaaacaaa attttaagag atcacaacaa atgaaccaag aaatggagag
     1621 ataaagatga ttaataatgt aactttagta ggacggttaa ccaaagatcc agatttacgt
     1681 tataccgcaa gtggcacagc agtagcgact tttaccctag ccgtcaaccg aaatttcgcg
     1741 aatcaaaacg gcaatcgaga agccgatttt attaactgcg tgatttggcg caaaccagca
     1801 gaaacaatgg cgacattagc taaaaaaggc ggcttgatcg gtgttgtcgg acggattcaa
     1861 acacgaactt atgacaacca gcaaggacaa cgtgtgtatg tgactgaagt tgtagcagat
     1921 aactttcaac tattagaaag taaagcagcg acagagagcc gtgcgcacgc tgatcaatcg
     1981 tccaccagtc caagcaccgc cacctttgaa caacgggata cagcgacgcc taacaacaat
     2041 ggattgaacg cttcacagaa tccatttggt ggacaatcaa tcgatattag cgatgatgat
     2101 ctaccgtttt agttcgagaa agaaggagta agcatggcaa aaaaaatagt ctgacgatgg
     2161 atctattgat acccgtaatt gcatttatag acgggatttc tttgggcgtc actgaaaatc
     2221 ctttggtaaa tagaattgcg aaaggatcac tatttcttgt attcgtgtat cttgtatgtt
     2281 cttatctttt aaaaagagca ggaagggata attccttttg gcgattgact aaagtcacaa
     2341 tagcagcgac agctgttata cttacggcta ttctaccgct ttatatgtag ggttaacggg
     2401 aaatcgttga acttcttgcg aaatattgct ataatgaaca tgaaaaagag gagttgcgct
     2461 aacaacccct cattaacagc accgattaaa gaacggtggc agaatattag ttatttggaa
     2521 ataaccgctg acctgctaaa gtggacggtt atttcttttt gtcattttta agcatattta
     2581 caatcaaact aatcaaagca atggtaaaca taccaaaacc aagaatggtt tgaattgtct
     2641 catatgcgga caaaaggctt actcctttca tagattttag cacttacatt cataagcacc
     2701 accacctttc cagaagtcgc caccgtcttc aaactttact gtcttgacta ttatagcata
     2761 tctaaaatcg aataaaaatt ctcaattttg gttgtttttg ctataatttt agcgaggtga
     2821 ttgtgatgga caaatatgtt ggtttgcttg ataaaatccg agtaataaaa acacaaccat
     2881 tattggttcg ctttacttta caaacaattc atgaatcgat taattgtgta gttgcagata
     2941 ttgaaattat cgataaactg ctaattatgg atgatggaaa atacaatatt gccgtcacag
     3001 gtcacttcaa taaacgaaat cagctagtta ttgctagcat gtatgttaga aatcccgatc
     3061 attttacgcg atcgatgggc atataaaaga agagttgtag tcctaaatga ggattgcagc
     3121 tctttttgtt ttacatagaa acgggaacag gaaaaggcct gtttaggaag gcacaagcgc
     3181 cttctcaatt gaaaaacctt tctctcactc caaccgccac cgccgttcga gaagaaagga
     3241 agtgaacgtt gcacgttcac taaaataagg ggtcttgcaa agcaagacaa aataggaaaa
     3301 acttcctctc accaaaaggt tcgttcctgt tcgctatctc tttattgatt tgccagaccg
     3361 gcaacaagtt gccttttatc accaaaaagc gacaaggaca agggtaaatg gcacgctgcg
     3421 cgcccttgtc cttgtcgctt ttcgttgatt cattctggcc aacaaatcaa taaagaaaga
     3481 actaacaaaa ggaagtaaac cctttcctaa gaggaggcag aatcaatcat gcgaaagaaa
     3541 tttgattatt ggggtgttcc cttcagcgaa ttattcccaa actatcatgc accacatact
     3601 gtcgaatgcg attgtggaga aagagcgaaa tgtatcaaaa gctatcgttt gtatcaatgt
     3661 caaacatgcg ggaaaaaata taccttgtct tatggcgatt atgttttgat tgatgagaaa
     3721 ggaaagaaac actgatgaaa acacaacaca aattattgac tgtaaaagaa gtcgttcaaa
     3781 ttttggtgga caaagaagtc atttctgaaa aagtagcaga agctttactt attccgcggt
     3841 actggacgat agaaacccct ttagtagagg atgcaccgac tatgctattt gaagacctag
     3901 tgaagattgc aggatatgaa ctgcattatc aagaaaacat ggaaacttat gaaaacgaat
     3961 attggttaac caaattagag aactaaaaag gagaaaaaaa tatggctcaa aattactatg
     4021 acgaatttgt caaattacct ttggataaaa tggcacaaaa aatggaggat atgacgttcc
     4081 tatacaacga aacacgtgtt ccaaagaaac attataaaga aaaattgtcg gtagctgtgg
     4141 aagaaatgat tgaatcaggt gtcgaaatga atctcattgc gacgtactat cgaacactgg
     4201 aagaactgaa aaagcaaaat gcaaaatggt ttttccaagc cttactatgc ttggaagtag
     4261 gcgtcaaacc aagcacaatc aaaccttctg aataccaagc tttagaacta acgtatgcga
     4321 aatttatcga aacgaaaaaa gccaagactg tttcaagtga atggttagat tattttgaaa
     4381 atatcaataa gtatggcgca tattacacca tgaaaaagga agacaacgaa aatgaataag
     4441 gtgatttatc aactaacaac ggattccata tcaacgattt gaaagaaaaa aaggtcaata
     4501 atcatttata ccgaaaagtg agaatgtgtg aaataaggac aaaaaaagcc tagtaactaa
     4561 gggaatggtt cttatttcgc accaatcgct ccaaccgccc ccgccgctta ggtgatgcga
     4621 aataaacggg caaagcccga taactcaaga gaaagaaggt gatccatttg aacaagatta
     4681 ttcccttatt gttagtacta tttgttggcg aaataattat gcgacatagt gcagctgtgc
     4741 atttaaactt cgtagtattt ttggtaatac tggtgttttg tttgatcttt tggcgctttg
     4801 tgttagccct tgtgagtcta atattcaagt tgattgcagc catatttttc atagggttat
     4861 ttcgatgaaa ggagagagta ctaatgccaa ttgcaatagg aaataaacgg ttacccgtta
     4921 cgttggatga aaagagacaa aaagaattgc agaaactaaa gcagaagtac ggaaaaagtg
     4981 aatctaagat tatgtgtatt gcgttagatc tattgatcgc gcaagaaaaa gcaggatttg
     5041 atgtaccagc actcaaaaag tgacgtcact tttcatttga agaaacaaaa gtgatagcac
     5101 ttaattgttc ctactattta gaatattttc tatatccttt ttattccatt ttgtatcaat
     5161 aactatgaaa tctttaaagt atccagaaga gattattttt agatcaattt ttttcttacc
     5221 tgattctaaa gattttgttt tcttaaacat attatgattt cctttcgact attttcatat
     5281 aaatgttaac atagtttatg gattcatgga atgttaatct aatttaatag aaaaggataa
     5341 ttaagtatat acgttttttc ttatgtatgt tatactatgt atatacagaa agaggtgtct
     5401 actatggaaa tgttacctat aaaaaaatgg ggaaatagta atggccttag attgccaaag
     5461 tatattatgg aatatcttgg aattcataca gaagacaaag tgaagataat acaagaagaa
     5521 gtaaacggtc agaagcggct aattatcgaa gcggctaata tagaaaatga attaacaatt
     5581 gaacagttat ttgaaaatta cactgatgaa agaaatcatg tgacgattca aaatttaggt
     5641 gaagcagtag gtaatgaaaa atggtgagaa aacctagaca aggcgatatt ctattattga
     5701 atacagcacc tcgatctgga cacgaacaga caggtaaaag gccttatatt gttttaagtc
     5761 atgatattat tgcggattat agtaacgttg ttacagttgc tccaatttct agtacaacta
     5821 gaaactatcc gctatatgta aatataaact cagaatatga aatgaagaca acaggaaaag
     5881 tattattaga tcaactaacg acaattgatt atgaagccag agagtgtatt tttttggaaa
     5941 aagcgcatga tagtttagtt gaggagttat tgatgaaagt tagaacagtt tttcaaaaag
     6001 taagcaaata aaatagaaac agcagcatga tcaactattc gtgattgacc gtgctgtctt
     6061 tttttattct atatacggtt tgtctcgtaa cattgtagtc ttttgcaatc ttagcgatcg
     6121 caacaccttt ttttagatcc tcaacgatgt ttttataaac aagacgacgt tggggatctt
     6181 ttgcattggc actgtatagc ttaggacgtc ctttataaac accgttcgct ttcgcaatct
     6241 taatgccttg tgcctgacgt cgtttagatt cggtacgttc ttgttcagcg atcatggcca
     6301 aaatttgaat gatcaaatct ttaatgaatt tatccaggag aggattgcca attgcttcgg
     6361 ccatgatcgg tagacttgta atgatcagct gcacattttt cttcttcaag taattgactg
     6421 aagcgatgat ctcgtcgtaa tttcttccaa gtcgatcaat agcttccaca ataaaaatat
     6481 cttgatctcg gacgtaatcc aatacttctt ggaaaacagg tcgatgagta attgtagcgc
     6541 cagattgttt ctcgatgaaa attctctctg caccgaattt tttcatttct tcaacttggc
     6601 gttgttcatt ttgatcgatc gatgagacac gtatgtatgc aactctcaaa tttttaccta
     6661 ctttctgcaa ctatttaaaa cacaccctaa tcatacatga gaaaaccaga tttttcaatg
     6721 tttgtcattt ttctagataa atggcataaa ttttcagcgc taagtgacaa aagcaactaa
     6781 tttttcatga tagattttta aatatctcaa tctatctcca aaattagttg cttttgtagc
     6841 tatagttgac tatgaatatg acaaataatt agaaaaaact gtgccaatta aatataaaaa
     6901 tgacactcat ttacattcaa tagaacacca agagcccaac agggtatact ctggtgtcct
     6961 tttaaaaaag taactttctg acctaattaa ttgagctact aaaaaagcta tgaaatgagg
     7021 aataaaaaag ggatcaaaaa cttttaagtt tctgaccctt ttgagttcta attatttctt
     7081 ccagaacgaa gaatgttatc tgctttatct gcaattgatt ctgttagaag gactgaaaaa
     7141 tttatgccag cccttttgcc tagcttatcc gcccattgag gaattgttaa ggtttttctg
     7201 acaagttcta tgtctttcaa atatttggca acatctacac agattaaaag catgattttg
     7261 tatcatagtc tattataaga gatttaacaa ttttttatat cacgaattaa taatgaaatt
     7321 atcattgata gtctttataa atttaattgt tctttttctt tactgatgtc ttccccatcc
     7381 ataatgtgac aggtaaaata tattcctttt ttgtttcttc tttatttatt cgtttcatca
     7441 aaatagcaac agctgtgtct gctatatcat taattggttg tattactgtt gtcagatctg
     7501 gtaatatact ccgagtcatt aaagtaccat catatccgac tactaataaa tcagctggta
     7561 catttaaccc cttttctttt gctacttgta atattagggc cgcatcgatg tcatttgaag
     7621 caaaaatacc atctatttta ggataatcct caaacatttg gaaaaaaatc tgttttttct
     7681 ttacataaga aatattgaaa tctaatgtca cagttcgtgg aattaactga tatgctttca
     7741 tagtatcttc ataggctagt ctccgacgat tagccggagt ctgtaagtca attggaccgt
     7801 ttgtatgaat aatatttttt gcaccttgtg caattaataa cttggttgca agttttccac
     7861 cattgtagtt atcggattca acaactggaa tatcttcatt catcactcga tcaattgcaa
     7921 caatcggtaa attctgatat ttatattcct gaattccttg gttatgtgta ccaacaatta
     7981 aaccatctac ttgatcagac aataactgat ttaaataatt tgtttccttt tctttattat
     8041 tcatcgaatt gcctattaat accttataac caatttcata taactttttt tccaatgcct
     8101 caacgagttc actaaaaaaa ggattggcta ctgtaggaaa tagtaacccg acaatgttag
     8161 ttttcttttg aaataattga cgcgctacaa cgttcggttg ataattgagt tcttctatag
     8221 ccttataaac attatcaatc gttttttgac ttaaatagcc acgattgttt aatacacgtg
     8281 aaacagttgt ttttgataca tttgctcttt tggcaacatc ttctaatttt gggcgcattc
     8341 tcttgtctct cctaaataat gcaataatta actatcgaaa aaaagaactc tatagaacta
     8401 ctatacctga taatcgatat tttttctatg ttttattctt gtaattgatt caagcccaaa
     8461 gcaaagtttc ctagtgttgc cgatccatta tttttaatta aaggacgcgt aatatattta
     8521 cttaacggtg gtatttccac gtaatcatcc aataatttat taacattaac acgaattttt
     8581 tctaacaatt tttcatttac tacgcttcca ccaaatacta ttttatccgg tcgtataatc
     8641 aatgttgttt gaatcacagc ttgtgctaga taataggcca ttacatccca aataggatcc
     8701 gttaaagaaa cgtcttcacc cttttttcca aaacgtgctt caaacgttgg tcccgcaact
     8761 aagccttcta aacaatcacc atgataagga caaattcctt taaaatcaat atcatcagga
     8821 tggcgtttta caaacgtatg gcccatttct gaatgaccaa acgatcctaa tagttttccg
     8881 tcaacaacag ctccaccacc aacgccagta ccaacggtgt aataaactaa tgaatttatt
     8941 ttttcattcg ataaagtgga catgatgtac tctccataag ctgatccgtt cacatccgtt
     9001 gtccaagaca ttggaacatt cagctcatct tgtaaataac ctaacacatt aacatttcgc
     9061 catcccacct ttggtgtaga cgtaatatat cctgattttg gtgaattttt tcgaatttct
     9121 attggaccaa atgatgcaat acctaatgca tttatatcaa actgtttaaa atagtcaaca
     9181 gtttttttca atgtttccct gggggtggtc gttggacaaa ttatttggtc ttgtactcgg
     9241 taatcctcgt ctcccacggc acatacaaat ttagtcccac ctgcttctat gctaccaatt
     9301 aacatcataa aacctcctta ctcgtaagaa attgcatctt tttttagatg ataaattgta
     9361 ctcgagacaa aagcttcttc actaacactc aaatgcatac ttggttgatt ttctgtataa
     9421 taacgctctg taaaaacaag ctcgccatca ttaataaaaa tctctgccga acttttatcg
     9481 ataaacactc gaagtgataa tctatcacac atctgaatgg ttccatacct tggatcattt
     9541 ttgccgttac gagttaaggt acattcattt ttatccttag aataaaaaat attgattaac
     9601 tcttcatctt ttgtttttaa tgaaaatttg atttcttgat tttttgattt agtcaatagt
     9661 acatcaatta gagcttcttt gaatgaagca tcttgagcga ttattatttc tcctgccaaa
     9721 ttaactgtcg tttcaacgcc gctgccaact cgaagttgtt ctaattctct cacaggtttc
     9781 atatacaaac gatctccaat taactctaat tctcgaggaa gcgttaatgc tcctgcccat
     9841 ccgtctactt tttcaggcat agggctttcc cacatatcca tccaggccat aacaatacgt
     9901 ctaccatctg gagataaagt tgtttgtgtt gcatagaaat cgtgtccctt atctaattca
     9961 taaaaatttc ctctaatgaa ttttgctgtc tcataatcat aatcaccgat aaagtagcct
    10021 gtttcatata gatttaaata atcttttcca tttgcttcaa ttccctgagg ggataataaa
    10081 agaatagatt ttccatttaa ttcaaaaaag tctgggcatt cccacataaa tccttctgta
    10141 agtacttcct tcgctttaga aattggtcca atgtaatccc aatttaataa atctaacgac
    10201 tgataaacaa tagcacgacc taatccatct ttttcttgac tacccaaaac catgtaatat
    10261 ttttcatcgt gtttccatac ttttggatct ctgaaatgat gtgtgttatc ttctggtgct
    10321 tttgctatta caggattttt ttcatattta gtaaagtgaa tgccatccgt actatacgcc
    10381 atgttttgat tttgccaaaa atgatctgga tcattgtctc cataatagtg atgtcctgta
    10441 tagaacagat acaacacacc atttttttca atagcgcttc ctgaaaaaca accaccttca
    10501 tcttcttgat ctccaggagt caaagcaagt ggtaaagatt cccaatgaac taaatcctta
    10561 cttctagcat gtgcccagtg cattggtccc cattcagcac tatatggatg atgttgataa
    10621 aacacatgat aatacccatc aaaatagcaa aatccatttg gatcattaat ccatcctgat
    10681 ggtgcagaca catgatatcc caaacgataa cgtgtatttg ttaattctat agcttttttt
    10741 gtcataatat attcgctcac tttctagata aaattgtttt ttattctgtt ggtttccatt
    10801 atcctcgaat aaatggatcc ccttgaacat ctctatcatc ttgtttaaga ataaagaatg
    10861 catatatgcc tgctagtaat acaataagag aaataatttt aaatgttggt tgatagccaa
    10921 cgttgtctct taatattccc aatggtgttg ataaaatcac ttgcccaatt tgagcagcta
    10981 tctgaaatcc tatcatatag agggttgctg atagctttgt atcaaaatga agtgtaaaat
    11041 agcgaaacat tggtaatgta aataatggta cttctaaagc atgcaacatt tttatgcatg
    11101 aaacagataa tggtgtcgag gcaaacccgc acaatccaat tcgtacacac ataatggtta
    11161 cacctaataa caaagtattt cgaaccccta attttctcat aatgattgga acaattccca
    11221 tcattaacgc ttcacaaaat acttgaatag cattcaatgt cccatatatt ttttcaccat
    11281 tagctgatgt tgaaaacaaa ccagtataaa atcccggaaa catttgttga tcgaataccg
    11341 tataaaatgt ccatgtaaaa acaataaaga tgattatcgt ccataattga ggcagtttca
    11401 ttagatcaaa catttctttt aaagaaggaa tactatttga ttcagcttgt tcttgattaa
    11461 aattttgatt tgcttcccgt tcaactttag ggttccaaaa taataaattt aacaatagta
    11521 aagaaccaaa gaaagatccc gcccaaaagt ttaaatgagg attttttaca aataaaaatc
    11581 ctgccaaaag cgctaccaag gcataaccaa atgatcccca cgcccttgct tgtccatatt
    11641 caaagccaaa taaacgacta aacctttctg acacagcttc aaaaactcct acagaagcta
    11701 aatatccagc tgacaaaaat agcgctccca taataatgcc taaattaaaa ttgttatcta
    11761 gcaatggccc atatatccat ataaaaaatg gtccaacaag tgtcgctaat acagaagcaa
    11821 aaattaataa atttcgttta atatacaatt tatcttgtaa tgttccataa ataaacatca
    11881 aaattaaggt aactaacgaa tttgccgaga atactgttcc tacagcactg ccagataacc
    11941 ctaaaccatt tgattcagat gttagccaaa gttgaaaaaa tgaccaccaa acaccccaag
    12001 aagcaaaaaa tagtaataat gtagctgaac tttgtaaata agattgattt ttaaatacgt
    12061 taacttttga catattttta tcctccaacg atatatttgt atcccctttc atgataaccg
    12121 gttaacattt ttagaaaagg acttgtactc ctaaaattat aaaagaaatc cgcttacatg
    12181 tcaaccggtt attctatttg gataatgcca tataatgtca caggatatga cttttattgg
    12241 tgtgtcgctt ttctttttta atggcactat tttttata
//
LOCUS       DADVXM010000073        12156 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.077, whole genome shotgun sequence.
ACCESSION   DADVXM010000073 DADVXM010000000
VERSION     DADVXM010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.077"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(36..593)
                     /gene="frr"
                     /locus_tag="KB927_002136"
     CDS             complement(36..593)
                     /gene="frr"
                     /locus_tag="KB927_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBB6841040.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(596..1318)
                     /locus_tag="KB927_002137"
     CDS             complement(596..1318)
                     /locus_tag="KB927_002137"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBB6841041.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1454..2335)
                     /locus_tag="KB927_002138"
     CDS             complement(1454..2335)
                     /locus_tag="KB927_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBB6841042.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2434..3216)
                     /gene="rpsB"
                     /locus_tag="KB927_002139"
     CDS             complement(2434..3216)
                     /gene="rpsB"
                     /locus_tag="KB927_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBB6841043.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3575..4054
                     /locus_tag="KB927_002140"
     CDS             3575..4054
                     /locus_tag="KB927_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBB6841044.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4271..5362
                     /gene="phnW"
                     /locus_tag="KB927_002141"
     CDS             4271..5362
                     /gene="phnW"
                     /locus_tag="KB927_002141"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBB6841045.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5355..6140
                     /locus_tag="KB927_002142"
     CDS             5355..6140
                     /locus_tag="KB927_002142"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBB6841046.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(6486..8177)
                     /locus_tag="KB927_002143"
     CDS             complement(6486..8177)
                     /locus_tag="KB927_002143"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBB6841047.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8599..9546)
                     /gene="arcC"
                     /locus_tag="KB927_002144"
     CDS             complement(8599..9546)
                     /gene="arcC"
                     /locus_tag="KB927_002144"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBB6841048.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9661..10680)
                     /gene="argF"
                     /locus_tag="KB927_002145"
     CDS             complement(9661..10680)
                     /gene="argF"
                     /locus_tag="KB927_002145"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBB6841049.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10771..12000)
                     /gene="arcA"
                     /locus_tag="KB927_002146"
     CDS             complement(10771..12000)
                     /gene="arcA"
                     /locus_tag="KB927_002146"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBB6841050.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3324 a         2535 c         2188 g         4109 t
ORIGIN      
        1 gcggaatgat ccgcccctct gtttttatga ttttattaaa cttccaataa ttctttttct
       61 ttatcagcag cgatcttatc tacttcttta atgctgttat ctgtcaatgt ttgtacgtct
      121 ttttctaatc cgcgcaaatc atcttcggta atatcaccat ttttttgttg ttttttatat
      181 tcatcgatcg catcacgacg gatgttacga atcgcgattt ttgcattttc tgcttctttt
      241 ttcacatctt tagctaattc ttttctgcgt tcttctgtca gttgcgggat aactaagcga
      301 atgacatttc catcattggt tggactgatt ccgatatcac ttgccataat agctttttca
      361 acatcttgaa gaatgctctt gtcaaaaggt gtgatcatta aaacacgtgc ttctggaatt
      421 tggattgatg ccatttggtt caatggtgtt ggcgcaccgt agtagttcac agtaatacgg
      481 tccaaaaggc tagcgttcgc acggcctgcg cggatttgcc caagttcacg ttgaagattt
      541 tgtgctgctt ttttcatttt ttcttttgct tctgtcataa ttgcatctgc catttttatt
      601 tcccccttac agttgttccg atattttcgc ctaagattgc acggcgaata tttccgtgtt
      661 catttaaatt gaagacaagc agtggaatat cattatccat gcttagtgaa cttgcagttg
      721 aatccatgac ttgtaatcct ttggcaataa cttccagatg agtcagttct tcaaatttta
      781 ctgcatttgc atctactttc ggatcagcag aataaacacc gtctacattg tttttagcca
      841 tcaggataac atctgcgccg atttctgccg ctcgtaatgc tgctgttgtg tctgtcgaga
      901 agtacgggtt gccggtaccg cctgcaaaga taacgatccg tcctttttct aaatgacgtt
      961 ctgctttacg gcgaatatat ggctctgcga tttgacgcat ttcaatcgaa gtttgcacgc
     1021 gtgtcggtac acccacgttt tccaacgtat cctgtaaagc taaggcattc ataactgtag
     1081 ctaacatacc catgtaatca gcttgagcac gttccatgcc catttgtgct ccgatttgtc
     1141 cgcgccagat atttccgcca cccacaacga ttgccatttc aacgcccagc tcgtgaactt
     1201 ctttgatttc ttggatgatt tctttgatta ctggtggttt gattccaaat cctgcatccc
     1261 cagctaaagc ttctccactc aattttaaga ctacacgctg atatttcggt gtgaccatgt
     1321 tcattcctcc aatattttct attgccattt taccatactt agatgatttc gacactctaa
     1381 gactggtttt tcttgttttg cttaaaaaaa gggagcgcac aaaccgtgcg ttcccgtctg
     1441 ttattcaaca gaattatttt ttcacttggc tcataacttc ttctacaaag ttatcttcgc
     1501 gtttttcgat accttcgcca acttcgaaac gtacgaatgt tttaacagtt gcgccttttg
     1561 atgcaacgta tttttcaaca gtcatatcag gatctttaac gaatggttgg tccaccaaag
     1621 cgatttctgc tttgaatttc ttcaagcgtc cttctaccat tttttcaacg atattcgctg
     1681 gtttgccttc gttcaatgct tgttctgtaa gaacagtttt ttcatgttct aattcagctt
     1741 ctggaatttg tgattcgttt acataacgag gattgatagc tgctacgtgc atagctacgt
     1801 ctcttgcaac tgtttcgtca gttgttccat ctagaacagt caatacggca atacgtccgc
     1861 ccatatgcaa gtatccacca aatgcagcat tgtcgtcttt ttctacaact tcaaagcgac
     1921 ggaagctgat tttttctccg ataacttgag ttgcttcgat caagtcagat tcaattgtac
     1981 ctttatctgt tttgattttc attgcagctt ccatgtctgc tggtttgttt tcagcaacaa
     2041 gttctgcaat ttcttttact aaatcttgga acatttcgtt tttagaaaca aagtctgttt
     2101 ctgagtttac ttcaacgatt gctgcagtgt tacctttcac agcaactgaa gccaatcctt
     2161 cagctgcaat gcggtcattt ttcttcgcag cctttgccat tcctttttca cgtaaaagat
     2221 caactgcttt ttccatgtcg ccttctactt caactaatgc ttttttcgca tccatcattc
     2281 ctacgccagt catttcgcgt agttctttta ccattttagc tgtaacgtct gccatgttta
     2341 actcctcctg tgtgtttttc tttttaaaaa aagctgcttc aaaggagagt gaggcttgtc
     2401 gcccagcctt tgaaacagct ccatcattca aaattattct gctgaagaat tgtcgccttc
     2461 aacaacatct acgatttctt cgattgatgt tgctgtgttt tcttctgtga aatcttcttc
     2521 aactacttga tcttcacctt ggtttccttc gatgaaagca tcagccattt ttgaagtaat
     2581 caatttaacg gcacgaattg catcgtcgtt tgaagggatt actacgtcga tttcatctgg
     2641 atcgcagttt gtatcaacca tagctacgat tgggatattt aatttgtgtg cttcttgaac
     2701 agcaatacgt tctttacgtg ggtcaacgat gtacattaca tctgggattc ttggcatatc
     2761 agcgataccg cctaagaatt tttcaagacg ttcacgttct ttgttcaaac cagcaacttc
     2821 ttttttaggt agaacttcaa aagttccatc ttcttccatt gcattgattt gtttcaaacg
     2881 gctgatacgt ttttggatag tatcccagtt tgtcaatgtt ccgcctaacc aacgatggtt
     2941 aacgaagtat tgtcctgcac gagttgcttc ttctttgatt gcttcttgtg cttgtttttt
     3001 tgtacctacg aataatgcta cgccgccttc ttcagcaacg ctcttcatgt aatcataagc
     3061 tgcatctact aatttaactg ttttttgcaa gtcaatgatg tagattccgt ttctttctgt
     3121 gaagatatat ttcttcattt ttggattcca gcgacgagtt tggtgaccaa agtgtacgcc
     3181 ggcttctagt aattgtttca tagaaattac tgccatgttt gtttcctccg atttggtttt
     3241 atttttcctc ttcttatctt ctaccttgcc ggcaaacttt ttcaagcacc taccgacaat
     3301 ccaataagaa tgtggatttg ctgatgcata aagcaccctc agctattata cagacaaaag
     3361 atccgtatcg caagagcaaa tatacttttc tgctcaacat tcaatagttt acctgaaaga
     3421 taaaaagaat tcaagaaaaa cagtagattt ctctttgttt ctttattatc ctttttccat
     3481 aaaataattt taggtataaa agacgaatat tattgggcaa tccttctttt ttttgttatg
     3541 atacatgtga aatctttcgt aaaggagaaa gaaaatgcgc aaagctcaaa gacatttgct
     3601 gattaaacaa gtcattgaag aattcccgat ccgtacgcaa gaagaactat taaacaaact
     3661 tgggcattat ggcgttaccg ccacgcaggc aacgatttct cgagatatcc gtgatctaaa
     3721 aatcgtgaag gcacctgatg aaaatggcgt ttcccgcttc gtattgtttc gcgaaaaagg
     3781 aactcctgag actaggactg aggaagagga tcggctggtt caaatgattg aagacattgt
     3841 attgaaagtc gaacgagtcc actttttgac gatcgtcaat accttgccag acaatgctca
     3901 tttatttgca tctgttttag atgagatcaa acctccctct attgtcagta caattgctgg
     3961 attcgatacg atcatggtca tctcggaaaa tgaggaggac gcaaaacgag tagaagaatt
     4021 tcttcaccat ccaactgaag tatcactttt ttaatcagag cacgtattcc taatatggaa
     4081 tgcgtgtttt tttattttca atattttcct tattaaataa acctttacac tctttacaaa
     4141 aatacatcat tttttattca attttttcaa caccttgatt gaatcacaat aatcatcatt
     4201 tatattggat gttaacaaga gcagcttctt gctctttgtg tatttcaaaa aagaaatgaa
     4261 aggaaatcat atgtataaat tattaactcc tggaccattg acgacttctg aaacagtgaa
     4321 aaatgctatg ctgatcgatc attgtacttg ggatcaagaa tacaaagaaa ttacacaatg
     4381 gataagaaaa aaattattgg atcttgctca agtatcggaa ggaatataca caacggtctt
     4441 aatgcaaggt agcggctcct ttggggtaga atcggtatta agttctgtga tcaggccaga
     4501 agatactgta ctgatttgtt caaacggcgc atatggacaa cgaatgatca acatgtgcga
     4561 atgtctgaaa ctgaactata ccgtttatga ggtatcggaa catcaaatcc tccaagctca
     4621 tgtgattaca cagctgattg aagagaatcc ctctatctcc gcactagcaa tggtccatag
     4681 cgagactact tccggtattt tgaataattt ggaagagatt gctgctgtca cacaagaaaa
     4741 agatcttttg tttatagtgg acgcgatgtc aagctttggt gggataccga ttcgtgtagc
     4801 cgaactaggg attgattttt tgatttccag ctcaaacaaa tgtattcaag gtgttccagg
     4861 cttttctttt gtacttgcta ataaagcgga actagaaaag cgaaaaaatg tgagtcgaag
     4921 tttgtcactt gatctatatg accagtaccg cgtgatggaa aacgagaatg gcaaatggcg
     4981 tttcacttcc cctacccata cggttttggc ttttcaacaa gcgctgaagg aactagaggc
     5041 agaaggagga atcgaaactc gatattcacg ttatctcgcc aataatcatg tactacgaca
     5101 aaaaatgaca gagatggggt tccagccttt cattcaagaa tatcaggggc cattcatcac
     5161 ctcttttctt taccctaagg actggcgatt tgattttaat catttttatc agtatttaaa
     5221 gcaaaacgga tttgtgatct atcccgggaa aatcagcgat catgaatgtt ttcgtatcgg
     5281 aaatattggc gagatctatc cggaagatat tttggaactg acagcaatta tcaaagacta
     5341 taaggagaac gttaatgatt aaaactgtaa tttttgattg ggcaggaaca actgtggact
     5401 ttggctgtat ggctcctgtc cacgctttta gaaatgcttt tctagaaaaa ggaatccaac
     5461 tgactgacaa agaaatccgc gaaccgatgg gaaaattaaa atgggatcat atccaacagc
     5521 ttctttccct cccttctgtc aaaaaacaat ggatagctat ttatggacaa ctacctcagg
     5581 aaaaagaggt ggaggaattg tatcaacaat ttgaacatta tctgtttaaa gatttggtca
     5641 agcattctac cttgaaaccc gacacattgg aaacgatcga acggttgaga aacgctggga
     5701 tcaatattgg ttccacgact ggatttactg ctcctatgat gacaatcgta gcagaaaccg
     5761 caaaaaaaga agggtattca ccagacttca tggcaacttc tgaagacgtc gaagggtatg
     5821 gtcgaccgtt tccttatatg atccataaaa acatgcagta cttcaaaaac aagtcggttg
     5881 atgaagtaat caaagtcgga gatacggtct cagatatcca ggaagggaaa aatgccggag
     5941 tgttgacagt aggtgtaatt gaaggtagtt cgctaatggg gatttcttat gatgagtacc
     6001 aaaaattaga gatggggaaa aaagatcgtt taaaacagtc tgttgctctt agattccaac
     6061 aagctggcgc tgatatttgt gtaaacaatt taaaagagtt aacagaatac attttgtacg
     6121 ctgacaagaa tccagaatga cttttataca aaatcagagg tcgtgaaaaa gctgtactgc
     6181 atcaagtaat aagaacagcc aaacaaaaat agctcctcat atttttcgtt tggttaggct
     6241 tattaccgca gatgcaagct tttgaacacc gtttattcga aaaaaaaagg gagctgtgac
     6301 acgacttttg tcacagtccc cttatttaca aacaaacagt gtttaagaga caacctctcc
     6361 actaaacggt gttcattcag ctgactctcg gtatttgctc aaaaaacgat aaaatttgaa
     6421 aagctatttt ctcttttgtt tctctaatac tcggatcaga acgctgattt cacattctct
     6481 ttttcttaca tcttatctgg tgcatgaagt cctagcaaac gaaggtcttc tttcaataat
     6541 acagtcactg cataaactag agctaagcgt gcttcttttt gttcatcatc agctaaaatc
     6601 ttcgtatgag catagtattt gttgaatgct tgtgctaatt tgattgcatg tttcgcaatc
     6661 actgacggtt cgtatttttc cccagcagac aagaccgttt cagggtattt ttgaactaat
     6721 ttaaccactt cccagctggt atcgtcattc aatgcatagt ctgctgtttc tgaagggaca
     6781 aatcctgctt tttccaacag gctgactgca cgagcatgtg tatattgcac ataaggtcca
     6841 gtttctcctt caaatcgaac aacttcttcc aggttaaagt caaatgtatt cagtcgatcg
     6901 tttttcaaat cgtggaaaat gactgcccca accccaactt gtttagctac agcatctttg
     6961 ttttccaaat cagggttttt ctcgctgatt tgttctttag cagattggat tgcttcattt
     7021 aatacttctt ctaataagac gatctttcct ttacgagttg ataatttttt accaccttgc
     7081 gtgatcaaac caaatggaat atggcgcata tcgtcagacc agtcaaagcc catttccttc
     7141 aagacagctt tcaactgttt aaaatgatag ctttgttcat tccctactac atatagagat
     7201 tgtttgaagt cgtaagtacg tttacggtac aatgcagcag ctaagtcacg tgtaatgtat
     7261 agtgtcgcac cgtctgactt cttaatcaac gctggattca ggtcataagc agataggtca
     7321 acgatctctg cacctttatc ctcgttcagc aaatgttttt cttctaaaag tttgacgatt
     7381 tcatccatct tgtcattgta gaaagcttca ccgttcaacg aatcgaaacg tacttccagc
     7441 agatcataga ttttattgaa ttctttcatc gattcatcac ggaaccattg ccataattga
     7501 atagcctctt catcgccttc ttccagacgt ttgaaccaag cacgagcttc ttcatttaat
     7561 tctggttctg tttcagctac ttcatggaat tggacatata aacgaagcaa ttcattgatt
     7621 ggttctgctt taacagcttc ttctgtaccc cattttttgt aagcgacgat cagttttcca
     7681 aactgtgttc cccagtcacc taaatggttg atgcggattg gctgataacc gattttttcc
     7741 ataatgaaac cgatcgaatt accgataact gtcgaacgca aatgtcccat tgagattggt
     7801 ttggcaatat taggagaaga catgtcgatt ggtactgttc cttgattccc gatattgcta
     7861 tccccataat gttctttttc tttcactact gtttgcaaaa cttttttgct gataagttct
     7921 ttattcatga aaaagttcaa gtaaggtccg acaacttcga ttttttcaaa gttggcagaa
     7981 tcgatttttt ctgctaaatc tgcagcgatt tgctgtggcg cttttcggta aacttttgct
     8041 aatgaaaagg ctggaaatgc aacatctccg tgttcagctg attttggatt ttctagtaat
     8101 tgttcgactt gttccagtgt taaatcatct ttgacagcgt catagacagc ttttgcgaca
     8161 agatctttat tattcatctt tattcctcct aaagtgctcc cttgattgtt aaacaaaaaa
     8221 aatctctagc gacggcatac ttagtatgcc atcactagag acgagatttc ccgcggtacc
     8281 actccaattg tcctaaaaaa ggaccagctc catctgatat cggtagacga ccgtctgttt
     8341 aaaacagaat tctccaagtg cgcttcgttg tatcttcttc attcggcttc caccacttcc
     8401 gaattcgcta gccaagaatg atacaagtac tctcttgttc aacaaatctt agtcttatta
     8461 aactttcttg aattatatca gaaaaaaaaa cgaaaggcta gtcgtttctg ataaaaaaac
     8521 aatccagatg gcctaaagga gaagaaatac cacctggata gctataaatc atttcgtaaa
     8581 tacgaaagac ttaacaaatt aatcagctac gataatcgtt ccttcttcag aagctaaaag
     8641 attctcgata ttttctaaag aagtgatgat tgccttagcg tttggttttg cttcaacaaa
     8701 tgcaatagct gcctctactt tcggaagcat gcttcctgga gcaaattgct tttcatcaat
     8761 gtattgtttc atttctgaaa cagtaacagt ttctaatttc ttttgatctg gtttttggta
     8821 attgacatac acattgtcta ctcctgtcaa tacgatcagc aaatccgcat cgatgatttc
     8881 ggctaatttt tctgaagcaa aatctttatc gattacggct tctcgtcctt ctaatccagt
     8941 agctgtttct acaacaggaa tcccaccgcc accaacagag actgtgataa ctccttgatc
     9001 gaccagcgtt tcgatgacac gtgcttcttt aatcgagatg ggtttagggg aagcgactac
     9061 ttttctccat ccacgtccag catcttcttt gaatgtcaca gtggagtcag cattcatttg
     9121 ttctttggct tcttcttccg tgtagaatgg accgactggt ttacttggat ttttgaatga
     9181 aggatcattt tcatccacaa taacttgagt gactaaagaa accacatctt tatcgatccc
     9241 tttttccttc agtacttcgc ccatggcatt ttgtaaccag taaccgatag atccttctgt
     9301 cattgcaaca catgtatcta aaggcattgc cggtgttttc tcagaatcag cagcttgctg
     9361 ctgaatcaat aggttaccga cttgcggacc atttccgtgg gagatgatca attcatctcc
     9421 ttgttcgata aatttcacta aatactttgc tgtttccatt aacgcttctt gttgggcttt
     9481 tgcacttgca tccgtagaca agattgcatt accccctaaa gcgacaacta cttttcgttt
     9541 ggccatttca ttcgtccttt cttcagttct accgaatttt ctagataaca aaacgagcca
     9601 gcgttttgtg attttccctc aatgctgact cgttttttcg tgagatgaat gtggttatgc
     9661 ttaaacgcga gggataaaca agttacctaa tgttgctgcc atgatcgctt tgattgagtg
     9721 catacgattt tctgcttggt caaattgacg agcatatttg ctgcggaaga cttcatctgt
     9781 tacttccatt tcagtgatgc caaagcgttc tttcatttgt tcaccgtaaa cagtgtttgt
     9841 atcatggaaa gctggcaagc agtgcaagaa gatcaaacga tctgtgttgt gtgttttttc
     9901 taccatttcc atattgattt ggtaaggttt caacaatttg atacgttctt cgaatttatc
     9961 ttcttcaccc attgataccc atacatcaga ataaaggacg tctgctccgt ctacaccttt
    10021 atcaacatcg tcggtaatca tcaattgtgc accggatttt tcagcaaagc cttctgccat
    10081 tttgacgatt tcttcttcag gttgtaattc ttttggtgca acgatacgca tattcgctcc
    10141 taaaattgca cctgtgacta ataaagagtt agccatattg tttcgaccat ctccgcagta
    10201 agcaacagtg ataccttcta ctgttccaaa gttttcttgg atagttaaaa agtcagcgat
    10261 catttgtgtt ggatgccatt catcagtcaa gccattccaa actggaacac cagagaattc
    10321 tgctagttcc tctaccattt tttgactgaa tccacggaat tcgattccat caaacatacg
    10381 acctagtact ttagctgtat cttctgtgga ttctttttta cctaattgga tatcatttgc
    10441 acctagatat tcaggatgtg cacctagatc gatcgctgca gtagtaaatg cagaacgagt
    10501 acgtgtagat gttttttcaa ataaaagcgc aatatttttt ccttctagat agtgatgtgg
    10561 gataccacgt tttttcaagt ctttcaagtg ttctgaaaaa tcgatcaaat attgtaattc
    10621 ttcttttgta aagtcttttt ctgctaataa gcttcttcct tggaatactg attctttcat
    10681 attaaacatt ctcctttaga ttgtttttat ttaagattaa agaggaaatc ccgacggcag
    10741 ctgacagtaa gaccgccgtc aggaaacaaa ttacttcaag tcttcacgga caagtggttg
    10801 gctcatgcag cgtggaccac cacggcctcg tgacaattca cttgaattga tttctaacac
    10861 tttgatgcca tagctacgaa gcaattcgtt cgatacataa tttcggttat aagtgactac
    10921 aacacctgga gcgattgcca atgtgtttga tccatcattc cattgttctc gaggtgcaac
    10981 gatctcatct ccattaccag ttgggatcag tacaagatca tctaatccaa gagcagcttt
    11041 catcgtttcg tgtaagttat ctgaatgagt aatcttgata tcatcaccat ctggttcgat
    11101 tgtaaagaca tccatcttac cgtctttact ttgaattgct ggatggatag tgaatttatc
    11161 gtgatctacc attgtaaata cggtatccaa atgcatcatt gcacggttgt ttggaatttt
    11221 gattgctaac actttttcaa atcctgaatt ttttgcgaat aggtggcgtg ctaatttttc
    11281 taaagctttc gcattagttc gttgagaaat cccaacagct actactttat cgcttaagat
    11341 caattcgtct ccgccttcga tatgatctgg attttcacga tccaaccata cttcgattcc
    11401 tttatttgca aatcttggat gatgtttcaa aatatattct gtaaacatcg attcacgacg
    11461 acgtgcttca aaagtcatct tattgactgt catcccattt cccattgatg cggaagggtc
    11521 gcgtgtaaag tacaagtttg gcattgggtc catgtaaaat ggatagtcat cgtctgctga
    11581 cagatcgtat agactgctag aacgtacttc aatatctttt gtacgaaccc cagccatgat
    11641 tttatctacc atttcttgcg tttccattga tagaaggaac tcatgaagac cctctcttac
    11701 agcattcgat gcaatatgag attcatccaa cattttattc aagaattgtt ctttgacatt
    11761 gcctgcgtca atcgcttctg ccgctaattt ttccaagtaa agagtctcga cgccttcatt
    11821 ttgcaatgtc tttgcaaagt tgtcatgttc ttcttgagca atcggaagat atggaatatc
    11881 atcgaacaac agacgatcca taatatctgg tgtcaaattt tccacttctt gtccaggcct
    11941 tttcagtaaa actgtcttta atttccctat ttcagagaaa acgtgaatag gtttatccat
    12001 gttgtgttgc ctccttcttt ttgattacat gtataggata tcctcctttt gtaatcactt
    12061 tcataatttt gtctcattca aaatgagaca ttcctcacat taatattcga taattaaata
    12121 attaaacgtt tttctatttt taagcgtaat ttattc
//
LOCUS       DADVXM010000074        11565 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.078, whole genome shotgun sequence.
ACCESSION   DADVXM010000074 DADVXM010000000
VERSION     DADVXM010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11565
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.078"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            229..435
                     /locus_tag="KB927_002147"
     CDS             229..435
                     /locus_tag="KB927_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBB6841051.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(637..1638)
                     /locus_tag="KB927_002148"
     CDS             complement(637..1638)
                     /locus_tag="KB927_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6841052.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1643..3556)
                     /locus_tag="KB927_002149"
     CDS             complement(1643..3556)
                     /locus_tag="KB927_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBB6841053.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(3724..4230)
                     /locus_tag="KB927_002150"
     CDS             complement(3724..4230)
                     /locus_tag="KB927_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6841054.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4390..4830
                     /locus_tag="KB927_002151"
     CDS             4390..4830
                     /locus_tag="KB927_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBB6841055.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(4856..6013)
                     /locus_tag="KB927_002152"
     CDS             complement(4856..6013)
                     /locus_tag="KB927_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841056.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFVKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6016..6372)
                     /locus_tag="KB927_002153"
     CDS             complement(6016..6372)
                     /locus_tag="KB927_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841057.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(6670..7644)
                     /gene="sgrA"
                     /locus_tag="KB927_002154"
     CDS             complement(6670..7644)
                     /gene="sgrA"
                     /locus_tag="KB927_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBB6841058.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(7840..8679)
                     /locus_tag="KB927_002155"
     CDS             complement(7840..8679)
                     /locus_tag="KB927_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6841059.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            8864..9751
                     /locus_tag="KB927_002156"
     CDS             8864..9751
                     /locus_tag="KB927_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBB6841060.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(10345..11040)
                     /locus_tag="KB927_002157"
     CDS             complement(10345..11040)
                     /locus_tag="KB927_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBB6841061.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(11024..11422)
                     /locus_tag="KB927_002158"
     CDS             complement(11024..11422)
                     /locus_tag="KB927_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBB6841062.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         3447 a         2309 c         1729 g         4080 t
ORIGIN      
        1 gggtatccta aatcttttct attatattcc catattttct attattggtc tagacgtatg
       61 atggtaaact ttgtacctat ctgattgctg aatcattaat tgcttatcat tagccatctt
      121 tgtttcaagt tcgctagatg atcattttat tcacatccta acaaacttgt cacatttata
      181 gattcttaat ctatttatca tacaattata aaaaaggagg tgctgcttat gaaagctatc
      241 catatttctt tgcttttttt cgctagtgca ttgattttat ttgctattca tctttgttcc
      301 cagccttata tcaataacaa cggaatatta gtggaaccag cattcttttg cttaccactc
      361 ggctttttgt cccttcttgc ctccgcaggc ttcggatttg ttgctttttt taaacgatca
      421 aaacaacaaa tctgacttat aaaatttacg taaaagagat cgtgacaata atcgtgtgat
      481 attcccaaat ttcgaataaa aggtgcccct tgccatctct aactcctcag tcacaagtta
      541 caatattcat aaaccatgaa aagcttgttt attgaaattg ctccttgtga cttggagcta
      601 agtgacagat tacaacctct tttgcatcat aagactttac tccttgaaaa acattactaa
      661 cttttgatat gtttcttgcg cttgtttatt gctgaaatca aactgatatt catggttcaa
      721 aacagcattt ttctccgcat aatctacttt tgtgactttc acccccgctt tctcaaatac
      781 agaagttact tcttccattt gtttcgtaaa cgtatttgta tttccatccg ttaagaatgt
      841 gttttgcgtc caacgatccg catgtctgac caaggctaaa cttttgacct tctctgattg
      901 ttcaaagtcc ttattatcaa agtaagccca tccacatttt tcataaagaa agctagagat
      961 tttatcactt acttgagtaa gtgcagaagg atccaacaga ccagacaaag aaataaactt
     1021 cgtaatctgc ttgttctcca aagtcggatc aagatgatca gcttttttaa tttcttcatt
     1081 ttgaagtgct aacaaatatt ctccactaat ttgtgcacct gccgaatttc caccaatcga
     1141 aatattcgac caatctgctt gatcttttat ctctttttta gctgcttgaa tggcttcgtt
     1201 caattggata actggtgtag gatgttttgc ttccggtgat cgttcataat ctatatttac
     1261 gatgatttgc tgcgtgtctg aacatagata ttccaaataa tcacgacaat catttttatc
     1321 ccctcctaca tatgcgcctc catgcatcca gaaaagaatc ggtaattttt tcttttccac
     1381 tttcggtgtg tagatatcca tattattatt tttgtacttt gaaggatagg atatttcttt
     1441 ttttatatcg atttgttcga ttttttgctg gaaatcatct ggtcgggcat atacttgttc
     1501 tttttcactt gtgtcaaatt gttttctaac aagcaagcta atcggctttg gtgtgatttg
     1561 attaatcaaa aatacagtga ctaaaataac tacgatgata actggtactg caatcactat
     1621 tcgcttgaac catttcattc atttaccctc tctttcttcg ccaaatccat gtgataatcg
     1681 tgctaacaga taaaaatcca cctgaataaa tgagaagcga atgtttcttt tctccagttt
     1741 tcggcaacat tctttttttt gcatctgtct ttttttgtac tttcactgtc atctgaatcg
     1801 gttgcgtatc atcacttgat tgatcctctc gaggttcatt ctttccctta ttgtctgcat
     1861 tctctgtcgg atcttgcttt tttggtggag ctactgggat ttttttgtaa tagaaaataa
     1921 tagttggtat cgtctcatta aaaatccctt cagtcggtcc ttcaacattt gctaattcgt
     1981 atccttcgaa tgtcttttgc tctgtcatat aattttctcc ataagctccg taaagctgga
     2041 tttcgtcctg gtctttgagt agacttttat tgttttcatc cacatacttt acgtttatct
     2101 gatcatggaa cactactttc aaaaagtccg ttacatgttt cgtgtaggca gcatggtcaa
     2161 cttcctgtgc ctttccatgc cctgctcctt ctactaataa aagatcttta taccctcctg
     2221 ataactcata taatttttgc gcgttagaca caggtactac atcatctgct gttccatgga
     2281 taatcaattt aggcaatgaa tctgacattc caatcgtagg tagagcagct tttgtatcca
     2341 aatgcatctc ctgatcaaaa tagtattgtt tcaaaaggcc cataaataaa tcttcatgct
     2401 cttgatcccc aatgatgtct aactgatttt ttatggcatc cggtagtgcg ggggctactg
     2461 tctggctgta cgtaaaacgt agttgttcat caattgatgc aaatccgcaa ttttcaataa
     2521 ttcctttgac attgacagga atatctttcg ctaatacaga catcatcgta gctgctccca
     2581 tcgaaccacc ataaagtaaa atcttttgag atggccgctc tcgaacttct tgatttatcc
     2641 agtaaaggac gtcatctgac tcatattgtc cataggtcac ataatcgcct ccgctattac
     2701 cagtcgctct ggaatcaaca aataataaat tatacccggc cttataaaaa tcattgtatt
     2761 cttctgtaac gatcccgtta ttccaattcc ctcgaaatcc gccatggatc atgactgttt
     2821 tatctgaacc ttgatcgaca taatatgcat atacatccat cattttgcca tcttgtttgt
     2881 ttagtacagt ttgatgaagt tgttttgtat ttggatagaa gcctgtgttt tctgtaggcg
     2941 ttgtcccatc atctgtacct ccaagcatcg acatcaacac actgtttttt gcaaaagcga
     3001 tatcgtacaa tagataagta gcaatcagat gtttgataat ctctttatct acaccataat
     3061 cattaacagc aagctcagtg actaataact ctattaattt tgacttgatg tcttctgttg
     3121 gtccattaag tatttctgtc atctgtttac cgaagtaatt caaatattct ttaccattga
     3181 aattttcacc tttaccgata tcatcatttt ctgtcccatt ctctttgtca cttactttag
     3241 cagaagagga ttcgtcgttt gacatttttg tagctgttgc ttcttctgtt tgttggttat
     3301 ctgtggtagc ggtcgtttct tgatctgtgc tagtaacaga tgtctcaacc gttgtttcag
     3361 tatttgtttc tgtttgtgaa gtactcgatt tcgtttcatt tccagcatca gtagtttctg
     3421 tggtttctac ctcccgagat tccgattcgg aagaaatgct ctctccatat actgtccatt
     3481 gcgggacgct tgtacttaca gcaaataaga tgaccaacgc tccctttaat acttgttttg
     3541 ttctcaagct attcactcct ttttatgttt ctaggagaat tatatgtaaa cgcaaacatt
     3601 ttttatacaa aaaataaatg gtttatccca taaaaataga acaggattat tttctcattt
     3661 tacgtaataa agcagaatgg ataaaccagt atccattctg ctttttttaa acgaagaaac
     3721 aacttattgc tccaaaaatg tcagaaatcg tttatcccaa attttctcgt aaaaagcgat
     3781 tgtttccttt gctttcataa aaggattatc ataagttgtc gttgctcctc tacacatcat
     3841 aagctggtat cctaatccat gagcaaactt cacagtcgta tctatacaat actctgcttg
     3901 tgccccacat aattcgatcg aatgacagtc caattcagtt aataaaacac tcaaattagt
     3961 cttataaaat gaattcgcat gggtttttct cacaaaataa ctgtgctcag gaatagataa
     4021 ttccgacaat agctcccatg gttttgtttg tggcactaat tgagcatctt cgtgttgaac
     4081 gaaaataact ggtttcccaa tcgtttcgta tgttttgatt cttttattca ctaatgctgt
     4141 cactgtttct aattcgtgta tcggcgaaga atcaaaacat accccttttt gtaaatcgat
     4201 cactactatt gcgtcggctg tgtttgacat acttgtgcct tctttctttt ttcttgattt
     4261 aatagtattt cttatctagc tagttccatt atacgtgaca acattttctt attttacacc
     4321 tctaaatggc acttttcgac tatttcttca tgttattatt tcataaatac ttagctattg
     4381 gaggaatgta tgatgattaa attgtataca ggttctggct gctcgtcttc aagacgcgca
     4441 aaacgttggc ttatcgtcca tgatataccg tttatcgaac agaacttaat tcgtcaacca
     4501 ctaaccaaaa atgaatttat ccacttacta aaattgacaa acaacggcgt gaccgaaatg
     4561 ctctctactc attctattag ttataaaaat cttgttcaca gaatagatga actcagtttg
     4621 agtgaactat atattgagat tcgtacatcc ccttctttat tgaaaaaacc gattatctac
     4681 gaccaatctg caaaactttt gactggattt agcgaagata aaatcaggat gttcctttct
     4741 aaaactaaaa gaaagcaaga gctcaacgaa ctcttgcttt ctggtcatct tgtcgatttt
     4801 aaagaaaata atctttttgc aatgtcttaa ttttggcata aacaatctgc ttttcttaat
     4861 taacgaaatc caatttttcc aatatggatc tatttttctc attcctgatt tttatgattt
     4921 cagctttcag acgcgcccaa tcattttttg taggttgtcc attccagtaa aatatctgtg
     4981 tattcgtttg atcatatgcc tttttgtcga taggataatc gctaatgaca atatcaggta
     5041 actgatcagc ggatgcacta tattttattg ggcgttcagt catagataat atccttttct
     5101 ttgcccataa ttcctgtgtt ttaccatact ttgattgaat atagaatatg acaggttgtt
     5161 cgtgttttac aaaaatatcc ctgactaaca tacagtattg aaaaatcaac cgtctgttct
     5221 tttcataata agtattaagc tctggaattc tgcgagctac cccactaaaa aactgttgca
     5281 tgattggata catcactgga aatatatgct gaaaatctct gtcttctgct gattttccaa
     5341 aagcatccac cttctttttt gtcccaaaaa cccttgaata caaatggatc attgccaaat
     5401 tgacatatag ataatttttt tctgaagttg taaaacaaat cttgaagttt ttttcaaaat
     5461 tttctacaat agacgattca atccagcccc aactttcttg tactttatct ggagtatcca
     5521 acaaatcttc ttccaaatag gtgttcatta caccaaacat aaaataaagg taagcttgct
     5581 ctgttggagt gatgtgattc atcgaccaga agtttgcttc aaaaaaaggc tctagtatgt
     5641 aatgcgtaaa ctcttctttt gttatcaatg gatgcacaaa tttgttcatc tcttctggga
     5701 catacgtaat cgagtggcct tgtttcattc gttgcaacga aattcttagt aggctgatcc
     5761 atttctttct atctatacta cgcgtatatg gcgcatgttt cgcaaatttt tctaatagtt
     5821 gacgtttatt ttttatactt gataatatat cagaatgatt ttcgtcgaat gactgccaat
     5881 acatcaagtg aaaaaagtat cggatacggt attcttctcc ttctatcgga ttaccttttt
     5941 tcaagctgca agataaatga tagtttttca aaatagtatt aagttctctt aattttcttt
     6001 gaatcgtacg caaacttata taattttttg actaagattt tctaaggatt gataagtacc
     6061 tttgtaaagt gaatccagta aaatataacc aatcgttccc tctaaaagta tagaataaac
     6121 tttactcagt aaaaactgag aagaaaactc gacttttatc atcttgtttt ctgaaagaaa
     6181 agataattta tattctggat acctttcgca aaacgattct gcttgttgaa tcaccgaatt
     6241 catcttagcc agggtgtagt ttagatctaa agcgatatcc ttcaccacat ataatttctc
     6301 gtctctttca taacaatagt tcaaaaattg atatacttgc ctttcattga tatcaataaa
     6361 ttcttcaaac aaagtacata ctccttttta tctattattt agacttattc cgacagctac
     6421 atgaataacg tacaaataga ttcgttactg atttttcaga gatactacca tgcgcagtgt
     6481 gcattgtcaa ttattcttgc tcttattttc catttgtgtt cctgttattt cctgtttctc
     6541 aaatatgtta gtaaacaaaa atagatctgg caaagctaca acttcgccag gcaatacagc
     6601 actctcgaat gaaatattca ctcaaaaatc tatcgtttta ttcaatttta gatctgttgc
     6661 ttttattctt tatttcactc gatggaagag agaacgaaaa tagcttgctc ctacaatcaa
     6721 aatgagtaac acacccatcc atgtaattag cttgttcaag gttctactac cagtttctgg
     6781 taaatcgctt tttctattat ctgtttcttt cgctttttct tgatgatcaa ttccacgaga
     6841 aacaaaatca ggctgtttta gcacactttt taggttgctc cctgcatttc tcttttgttc
     6901 cttagttggt atgataggta ccaaatcaag ttcattattt acttttcctg tgctgctttc
     6961 gctgctcgtg cttcctgtgc tactctcact actcatgctt cctgtgctac tttcactact
     7021 cgtactctcc gtactgcttt cgctgctcgt gcttcctgtg ctactttcac tactcgtact
     7081 ctccgtactg ctttcgctgc tcgtgttttc tgtgctactt tcactgctcg tactctctgt
     7141 actgctttca ccgctcgtgt tttctgtact gctttcacta cttgtgctat ccgtactgct
     7201 tggcggtcca acaactgtcc aactgcttgg tttcaaattc tccgtgatcg tcatctgtcc
     7261 atcataaaaa acaatcaaat caactttatc tttactcttg atctcatcaa tcgatagttc
     7321 tgcagaaatc attattgtat actcaatacc agcggtccat tgtacgtctt ttaaataaac
     7381 ttccccaata actttttctg aacttccatt accatcccaa ccatatgtta gaacagcatg
     7441 tacatcacta gcattcacgc ttttgtttgg tttgactgga atagtaatga cttgttgtgt
     7501 catgtcataa acaatccgat cagttttcac agtaaatgaa agattctcat ttgcccgttc
     7561 atttgcagaa gtactgattc caatcattgc tgcaattata ctcagcccaa gaataacaaa
     7621 taatacggtc gctgttttct tcatttctat cactctccat ataattacct tctatttgat
     7681 aaaggaatta tataaaatga aaatgatgag aacacgacag tcagttgtga aaatctaaca
     7741 aaagatgtcg tgtattcgct tgaatttgtt tactttttcg tttaatcaat gacagactta
     7801 aaaaagcaag accgatatca gccttgcttt cttcatcttt tattgataaa cagcagtgta
     7861 tttcttcatc cgctttgttt tatatgcata gagtaacaaa ccaacaatca agactaacaa
     7921 gaataatgta gttgatatag atgcttcagc cccaaagttt cccccagtaa ttattgtatt
     7981 ttgcgattgg atcagagtgg agaaaaaacc ttgttcttgc gttccgctga ctggtatacc
     8041 caaaatagct ccttgtgtcc aattccaagt aatatgagca ccaatagccg taaataaact
     8101 tcctgtactg tagataagtg cgctgaaaaa gcaacctgct aaaaagatat tgaaaactgc
     8161 cagaaatgtc atgttaggat tcaatccgtg caaaagagca aataatgcag cagatccaat
     8221 cattgctatt aacggaccaa atctaagcat ctgatgctga aaaaagccac ggaataaaag
     8281 ctcttctgat gcccccactg caataaataa aataaaactc gttatcagcg gcacaatgtt
     8341 tgcgtttcct gaatctaacc gatacgcccc cgtcaaatat aatggactag taataagcag
     8401 aaacactcca attccaacaa cgagacctcc cgctaaatac ccccagtctt ttcctcgaac
     8461 agaaacacca taatcttcta ttctttttcc ttcgacctta ctagcaagaa ataaagctag
     8521 taaaaaaaca gctaaatgtc cgaccgtacc ggcaattgct ccaatccatt cactatttcc
     8581 aataaacata tccgcaagtg cattattgac aagaattcct aaaacaaaac caactaagac
     8641 tattaaaaca gatccaatca accgaataat cctgatcatc tttcatccct cctttatatt
     8701 aagtttaaca acccttttct ttcttgtctc gtgaaaacta tgtaaatgtt ctccatcata
     8761 gagagaatag atttttacga actaagaata tctacagcaa ccttacgaaa atgaaagact
     8821 gtctccctaa ttcttctgtt agactgtttt taataaggaa aggatgggaa attttttgaa
     8881 aaaacaacta ctaattatgt gcctttcagc atgtgcaatt ttactattct caggttgtag
     8941 caagtccaat gaaacgattg caacgtttaa aggtggaaca cttacagttc aggattttta
     9001 tgataaccca aaagttaaat caaataatca aacactatta aaaaaaatga ttgtcttcaa
     9061 agcatttgat gatgtatacg gaaaagagat ttcttcaaag gaagtaacaa aagaatataa
     9121 tgaacaaatc aaaaaactcg gtccaaacta caaggaacaa ttaaaagcag ttggccaaac
     9181 agaagagaca tataagaaac tctttaaaca gatgctggct ttccaatacg gtttgaaagc
     9241 caatgtaaaa ttaacagata aagatctaga cactgcttgg aaagaattct atccagaagt
     9301 tagtacacag atcattctat tttcgactaa agaagaagca gataaagcaa aaaaagaagc
     9361 aaatgaagga gaaaatttct ccaagcttgt tcaagcttat ggaaaaaata aaacattaaa
     9421 ggaaactgat ggaaaaatga attttgattc aaccaatcca gagattccta ctgaagtaaa
     9481 aaaagcagca tttaaactaa aaaacgggga agtttctgat atcattcctg taacagatcc
     9541 aacgacttat cagcaaagct attatctagt aaaaatggta aaaaaacagg ataaaggttc
     9601 taataaagac aaatacaaat ctgagctaga aaaaattgct accgaagcaa aaactcttga
     9661 tacggaattc atggataaaa caatccgtaa agtgatgaaa aaagacaatg taactattaa
     9721 agatccttat gtaaaaaata tattcaaata aacaaatttg acccaattgg ggatgtggca
     9781 aaatttgaga agtgattttt ggaaattcct tcttattttt gaggcaaacc acttttgcca
     9841 caacttcatc ggggcctttt tttatttgta ccaaaacaaa tcactggatt tgttacaatc
     9901 atgaggatat aatttaaaaa agttttttat ttctatcaca tgaatcaatg cgccattaag
     9961 tagattcttt catgcttccc tattttttca cttgccgtat cgcttcaaaa acaactatca
    10021 taaactcaaa ctcgactgaa aagttatttt aaaaaagact aaaaatatcc cttctggact
    10081 tgttcttctt attctgttat actagagaaa cacgaaagat atttttatgc gacacttttc
    10141 atttgttttt atgaaattta ttcaaaactg gcgtaacttc agagttacaa ggatgtatta
    10201 gaggttaggg aatacatcgt ttaaatgaga aataagtaat agttagtaat agtcacccaa
    10261 actttaaatt aatgaatatt gaatcgtcag atagcctcct cgagttttcg agaaggctat
    10321 cgtttatttt atggagaaat tgattcagaa gtaatcagcg acctttttta gttcaccaat
    10381 cgtttctgct tggaaagttt gcacccaatc ttcttggaag cccctcactg ctttatcaat
    10441 cgagggcatc tctaatactt gatctagtag ctctttacct aacgttatcg catgagctcc
    10501 agatcgaatg gctgtagtga cttgttcaca atttttgaaa ctagctgcta atatttttgt
    10561 tggtctttgc gtacgttcga tctcagtccg caacgaatca atcactttca tagcatcaat
    10621 gccttgattt tgcatcctgt tataataagg tgcaatataa tctgctccat tattaatagc
    10681 taaataccct tgtaattctg tgtaaatagc tgtaccggta atcaaataac cttctttttt
    10741 caactttttg atcgcttgaa ggcctgcttg attcaccggc accttgataa acgtatcttt
    10801 tcccagttct tctatgataa ctcgagcatc ctctatcatt tcttcttccg ttcttcctat
    10861 tgtctgaata tggataggaa tctgtccgat tatttttttg atttctttca tatgcgagaa
    10921 gaagtttgac gctccttctt ttttcagaat tgtaggattt gttgttacgc ctgttaaatt
    10981 caaaaactgt tgacaagaat aaatactttt tgtatttgct gtatcaagca tgatttccat
    11041 atagctttcc cccattctga tcctcttgat cgattttaat gattgtcccc tttcttaaat
    11101 gcggcatttc cttatcttct acatacattg ttcctggaag ttccggctca tgagatccat
    11161 caaattttat cgtgatatgt cctaattcat tcaaattagt ttggacaaca tctcctactg
    11221 ctgtgattac atacatttgt ttatcaaaac agagcttcat atcacaagtt atttcttttc
    11281 ttacctgatt caattcaatc ttataacaat aatctgttaa tgtttccggt gcttcatctc
    11341 caaataaaat cattattttt tctttcctga atacttctgc ttctatacca acatctgtta
    11401 caaccgtttc aaagatcgtc atctctgttc ctcctcgtaa aatatcattt gtctaatagt
    11461 ttttattcaa aatgtttcta gattataaaa tttattgaat aacacattcc taacggaatt
    11521 tgtttcgata ttgtgtgatt tctcagagta caatggatgt atgga
//
LOCUS       DADVXM010000075        11483 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.079, whole genome shotgun sequence.
ACCESSION   DADVXM010000075 DADVXM010000000
VERSION     DADVXM010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.079"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(179..664)
                     /locus_tag="KB927_002159"
     CDS             complement(179..664)
                     /locus_tag="KB927_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBB6841063.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    754..1099
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1144..1785
                     /locus_tag="KB927_002160"
     CDS             1144..1785
                     /locus_tag="KB927_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6841064.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            1804..2439
                     /locus_tag="KB927_002161"
     CDS             1804..2439
                     /locus_tag="KB927_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6841065.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2457..3272
                     /locus_tag="KB927_002162"
     CDS             2457..3272
                     /locus_tag="KB927_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6841066.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3591..5027
                     /locus_tag="KB927_002163"
     CDS             3591..5027
                     /locus_tag="KB927_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6841067.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5216..7663
                     /locus_tag="KB927_002164"
     CDS             5216..7663
                     /locus_tag="KB927_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBB6841068.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7893..8960
                     /gene="rlmN"
                     /locus_tag="KB927_002165"
     CDS             7893..8960
                     /gene="rlmN"
                     /locus_tag="KB927_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBB6841069.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(9153..10256)
                     /locus_tag="KB927_002166"
     CDS             complement(9153..10256)
                     /locus_tag="KB927_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6841070.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            10809..11357
                     /gene="aac(6')"
                     /locus_tag="KB927_002167"
     CDS             10809..11357
                     /gene="aac(6')"
                     /locus_tag="KB927_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBB6841071.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         3808 a         1943 c         2480 g         3252 t
ORIGIN      
        1 cttttttcgt agaatcaata aatatggatt tggctaacta tggaagaata ctcgtattag
       61 ttttcagcgt tcatactagt tgttacattg tttgattggc caaaagaatt tctgatatat
      121 tttgtgctaa ataaagaaaa agacgcttga attgggaaat aagaaaacta ctctatcatt
      181 acaaattttc ataaactggc agatgttcta agtaaacaag tatcttttca aagtcggaaa
      241 aatccataat caacgtagtg gtattgatat ttggatgaaa gcctacggta tcttgacgat
      301 caatagcagc atcgatcacg acttggattt ttttctcttt gtcgtgcatc aatgctaatg
      361 gagtcactgt acctgctgga acgcctagga ggtcaggaag ctgttcttca gaaacaaaag
      421 ataagcgctt ttcttttaat tgttcagcta gttgttttaa atcggcgtgc ttttcatcag
      481 gcaagatgac aagatagatt tgttttcctt ttcttgattt caataataga ttttttactt
      541 gcggaccagg tagggaaaaa gggacatttt tgactgacgt aatcgcagga tgatcgactt
      601 tttgaaaaga gatacccagt ttttttagta gttcataagc ttcttgttcg gttgcacgac
      661 tcatcgcgca tcaccctcct ttttttatta gtgtatcata aaaaagagtt gacaaatgaa
      721 aaataatcat gtaaattaca cgtaaagtta aaacaaatga catcgaaaag aagagtagcc
      781 gttaggtgtt tttagagagt ctctggttgg tggaaagagg cagcagttaa ccgtgaaaca
      841 catcttggag tcgattttct gaagcgtata gtaggaaaat ccggggagcc cgttacagct
      901 gcggtcgttg ctagatgacc agataaggct ggcttttccg tgaggagtcg gtaaaaaaag
      961 gtggaaccac gtgattaacg tcctttgatc ttcggatcaa aggacttttt gttttcatct
     1021 gaacggcaac gactgtgtga ggttttttct gcaaggaaaa aataaacaga ggtggaacca
     1081 cgtataatac gtcctcttgg catttgccaa gaggattttt ttattttaaa ggaggaaaag
     1141 aagatggagt atttgattga agttatgccg caattattag taggagcact cacaacattg
     1201 aaattatttt tatttacctt gattggctca ttaccattag ggattgtttt agcattagga
     1261 ttgtctttgc attttaagcc gctacgctac ttgcttcaaa catatgtatg ggttatgcgg
     1321 ggaacaccgc tgttgttgca actgattttt attttttatg ggttgccgac gattgggatc
     1381 gtttttgatc gtttcgaagc agcactcatt gcctttatct taaactatgc agcttatttt
     1441 gcagagatct ttcgtggagg gatacaatcg attcctcaag gtcaatatga agcagcgcaa
     1501 gttttgcaat taagtccctt tcaaacggtg acgaaaatcg tcatcccaca agtgacaaag
     1561 attgttttac cttctgtagg gaatgaagtt atcaacttgg tcaaagattc ttccttgatc
     1621 tatatattag gtttaggtga cgtaatgcgt gctgggaaaa tcgcgatgga acgcgacgcg
     1681 actttactgc ctttgctagg cgtggcaatc atctatctta cattgactgg tattctaaca
     1741 atcgtaatga aacaagttga aggaaaatta aattattacc gctaactgat aggaggaaga
     1801 aatatgattg aattgaagaa agtgaacaaa gcatttggtg aaaaaaaaat aatcaaagat
     1861 ttgaatctaa tcattccaga tgggaaaaca ttagctatcg taggtccttc cggtggcggt
     1921 aaaaccacgc ttttacgtat cttggctggc ttagaaagtt ctgacagcgg agaattttat
     1981 ttagacggtg taccgttcaa cccattcgag cttaaaatga aagaacaagt tgtaggagtc
     2041 gtattccaag acttccagct atttccacat ctgaatattt ttgaaaacat taccttagca
     2101 ccaaaaatgg tattgaaaca gacaaaagaa gaatacacca aaaaagcaga agaattagcg
     2161 gcttcattag ggattagtga tttattgaat atctatcctt atcagctttc tggcggacaa
     2221 aaacagcggg tagcgattgc cagagcattg gctatgaatc cacgggtatt ggcttatgat
     2281 gaaccaacaa gtgctttaga tcctgaatta cgccagcaag tcgagcgttt gatcctatca
     2341 ttgaaagaag atggggtaac ccaaattatt gtcacccatg atttagtatt tgcagaaaat
     2401 gtcggtgatc aattactaaa agtttcccca attcattaag aaaggagaag atagagatga
     2461 aaaaaaccag ttttctattc gctttgatcg caggtcttct tctttttgca ggctgttcga
     2521 acaaaaaaac ttcagcagat aattgggcga ctatcaacga agagaaaaaa atcgttatag
     2581 gtttagacga tacatttgtt cctatgggat ttagagataa agacgggaag ctcacaggat
     2641 ttgatattga tttagccaaa gcagtctttg aacaatatgg gattacggta gactttcagc
     2701 ccattgactg gtcaatgaag gaatttgaac tgaacaatgg aacgatcgat ttgatatgga
     2761 acggctattc caaaacgccg gcaagagaaa agaaagtgca atttacaaaa ccttatatgg
     2821 aaaacgatca agtgctgatc acacctaaag aatcaggaat cacaaacttt ggacaaatga
     2881 ataataagag attaggtgcg caaaatgggt catctggtta tgatgtattt acgaaacaac
     2941 cagaagtatt aaaagagata gtcaaaaacc aagatgctgt tttgtatgat agttttaatg
     3001 aagcattgat cgatctgaaa agcagacggg tcgatggtct gctgatggat aaagtatacg
     3061 cagactatta tttgaaacaa agaaacgaac tagaagactt caacataaca aaaggttctt
     3121 atgagagtga ggattttgca gttggtgcac gcaagtcaga tagtacatta gtgaaaaaaa
     3181 tcaatgaagc cctagatcaa ctagagaaaa caggtgaatt ccaaaaaata tccgataaat
     3241 ggtttggcga agatgttacg ccgagaaatt aacaaatagg ggactgtgac aaaagacgtg
     3301 tcacagtccc tttttccgaa taaacagtgt tctcctgcca actccttgtg actcggagct
     3361 gaatggcagg ctcacaacct cttggtaaac ggtgttcaaa agccagtttt tcggtattaa
     3421 gccaaattta tgcaaaaatg tagaaagcca ttttcacaaa atttttctta ctactcgaaa
     3481 ctaagcgact ttttcacaac ctcctttaca tatttttatt ttgttgtgga aggggtttcg
     3541 tgttattcta aaagaggaac gattgaaggt tataggaaag gaagagatga atggaacaca
     3601 aagaacttac ctcatttcca aaagattttc tgtggggctc tgcttctgca gcgtatcaag
     3661 tagaaggagc ttggcaagaa gatgggaaag gagaatcagt ctgggatcga tttgtacgga
     3721 tacctggaaa gacatttaaa ggaacgaacg gtgatttggc agtagaccac tatcatcgtt
     3781 ataaagaaga tattgcttta atgaaagaac aaggtctgaa agcttaccgc ttctctgtag
     3841 cttggacacg gatttttcct aatggacgag gagaagtcaa tcaagctggg ctcgcttttt
     3901 atgagagatt gatcgacgaa ttgattgaaa acgatattga acctatgttg actttatatc
     3961 attgggatct tccacaagca ttgcaagatg aatataatgg ttgggaatca cgtcagatca
     4021 ttgaagattt cactcattat gcagaaacat tatttgaggc attccgcggg aaagtccatt
     4081 actggattag tttgaatgaa caaaatatct tcacttcatt aggttatttg ttagcagcac
     4141 atccgccagg tgtgacagac ccgaaacgaa tgtatgaagt taaccatatt gctaatttag
     4201 caaatgcatc tgtcatcaat aaatttcacg agttagaaat gcctggaaaa atcggaccaa
     4261 gctttgcgta tacgccaaat tatccaattg acagtaatcc tgaaaatgtt ctggctgctg
     4321 aaaatgcaga agacctgatg gccaattatt ggatggatgt ctatatgtgg ggaaaatatc
     4381 cgattgctgc catgaggttc ttagaagaaa aaggatgggc accaacgatt gaagctggcg
     4441 atgcagaatt gctagaatct gctaaaccag attttcttgg gatcaattac tatcaaacgg
     4501 cgacgaatgc attcaatcca ttaaacggag ttggtgctgg aaaaatgaat acgacaggaa
     4561 aaaaaggttc atcagaagaa actggagttc ctggaatgta taaaaaagtt gagaatccat
     4621 ttgtcgaacg aacaaattgg gactgggaga ttgacccaga aggattaagg atcggactgc
     4681 gtcgtatcac aagccgttac cgcatgccgg tactgattac ggaaaatggc ttaggagagt
     4741 atgacaagtt gacagaagat aaacaaatcc atgacgacta tcgaatcaat tacttacaaa
     4801 gccacgtcaa agccatcaaa gaagcaattt cggatggagc agaagtccta ggctattgca
     4861 cctggtctta tacagatttg cttagctggc tgaacggtta tcaaaagcga tatggatttg
     4921 tatatgttga tcaagacgaa acacaagaag gatctttgga acgatataag aaagacagtt
     4981 attactggta ccaaaaactg attgaagaaa atggagagaa cctttagttc acatacttaa
     5041 aacaagaagg tacggctgga tatggccgtg ccttttcttg ataaaatcat ttagaaatta
     5101 agaaaaactg taaaataagc tgaaaaatga aagaaagcgt cagttctttc aaacaaaact
     5161 ttagttccct tacttttttt tgtataatga aacttgatga aatgagggat aataaatggc
     5221 acaaaagaaa cggcctacta aaaaaaggaa aaagacgaaa aaaacgaaaa agcaaaaaca
     5281 gcagcaggaa caaatgctga cgattggtgt tgggtttgcc ttgattttat ttgctgtctt
     5341 cggcttttta aaattaggtt ttttaggaat attgattgca aacggctttc ggatcattgc
     5401 aggaaatact taccaaatcc tctgtctttt attagccgta ttaggatttt ggattgtcat
     5461 taagaataca gagttttcaa ttggtaaaaa ccgacgctgg tttggcggca tactctttta
     5521 tttcggtatc ttattattgt tacatgccca tttatttggc aaactccata ctggggaacc
     5581 aaatatcatg gggacgacat gggatttgtt agccagtgat ataaaacaaa gtcaagtaga
     5641 caataacgtt ggtggtggga tgattggagc aatcctttat cattttactt acttcttgat
     5701 tgcacagcct ggaagttatt tagcagcagt gctattactg gcaggaggag cattcctgtt
     5761 cagtaatctg gaaggctatc agctgttaaa tggtatccaa tcaattggag aacgagtaca
     5821 ggaattattg gaaggtgatc ctgccaagca agctcgaaag caagcggcaa aggaagagag
     5881 aatgaaacag cgcgcagaag cgaaagaagc aaggcgctta gctgcaaaag aagctgcaga
     5941 aaaagaagct gcagaatatg agaagaaaaa agcggtgagc cagcaaaggg aaaatactgc
     6001 tgatgaatgg caggaaccag aaaatacaga gccggagcag ctaagttttg ttccaatcga
     6061 cagttttcaa gaaaatatcc atcctgcgaa tctagagaaa ccagtaccag atacaccaaa
     6121 acagaccaat acagcagaag gtttttcaga tgagttgcca gaggatgacg gtacctcatt
     6181 agaatttgag attgaagcag aacaggaaaa tcaagactat gaattaccga cagttgattt
     6241 gcttgattct ataccaactg tggatcaaag tgatgagtat aaaaaaattg aaaaaaatat
     6301 cggcgtatta gaacaaactt tccaaagttt cggtgtcgat gccaaggtcg tcaaagccag
     6361 cttaggacca tccgtcacaa aattcgaagt ccagccggct gtaggggtaa aagtaagtaa
     6421 aattgtgaac ttaacagatg atatcgcgct tgctttagcg gcgaaagatg tccggatgga
     6481 agcaccgatt ccaggtaaat cactgattgg tattgaagta ccaaatggaa agatcagtat
     6541 ggtttccttt agagaaatca tcgaagcaca accaaaccac ccagataaat tactagaagt
     6601 acctttagga cgtgatgttt ctggacgggt acaaacggct gatctttcga agatgcctca
     6661 cttactcgtg gctggttcga ctggtagtgg gaagtcagta gcaattaatg ggattatcac
     6721 aagtatatta atgcgtgcta agccccatga agtaaaactg atgatgatcg atccgaaaat
     6781 ggttgaattg aatatgtaca acggcatacc tcatctgttg acgccggtcg tgacgaaccc
     6841 tagaaaagca gcgcaagcct tacaaaaagt agtacaagaa atggaagaac gatatgaaaa
     6901 attcgcggca accggagtaa gaaatatttc tggttacaat gaatttgttc aacagaaaaa
     6961 cttggaaaac ggaacgaaac atccaacctt accattcatc gtagtgatcg tagatgaatt
     7021 agctgatttg atgatggtag ccagcaatga agttgaagat gcgattattc gtttagcgca
     7081 aatggctcgg gcagcgggga ttcatatgat cctagctact caacgtccaa gtgtggatgt
     7141 tatcacagga atcatcaaag caaatgtacc ttccagaatg gcatttgcgg tatcaagcgg
     7201 tacagattct cggacgatca ttgattctaa tggggcagaa aagctcttag ggcgaggaga
     7261 tatgctattc ttgccaatgg gtgagaataa accgatccgt gtgcaaggag cattcatttc
     7321 tgaccacgaa gtagaacggg tcgttcaatt tgttacagat cagcaagaag ctcattatga
     7381 agagaaaatg atgccgacag atgaagttga aacgacaggt gctccagaac agccacaaga
     7441 tgagctgttt gaagaagcaa aagcacttgt cgttgaaatg caaacggcaa gtatttccct
     7501 tctccaaaga agatttcgga tcggttacaa ccgagcagca cgtttagtag atgaactgga
     7561 agctcatgga gttgttggcc cgtcagaagg aagcaagcct cggaaagtat tcattgagca
     7621 ggaagaaaca tcagaaacgt tgccggacga taatgacatg taaaacttgt gtgatgaagg
     7681 gttgaaaaac gaataaccaa taaaaagaca aggcatgatg ataccaaaag aaaaaatggt
     7741 ttttttccat cttttctaat acggtatgat gtcttgtctt tttagttttt gtgagattaa
     7801 agttctattc gatttatttg tgaagtattg cattaaggaa atgaatcatg tatagtatgt
     7861 agcgaaactt tgagaaaaag agggaaaata ctttggaaaa acagtccatt tatggcttga
     7921 cgaatgaaga attaatcaat tggtttatag aaaacggcga gaaaaaattc cgagctgccc
     7981 aagtttggga atggttgtat caaaaacgtg taagtaattt cacagaaatg acgaatctat
     8041 cgaaacaatt gatcgaaaaa ttatcggagc attttatcat caatcctcta aaacagatgg
     8101 tcgtccaaga agcttcggat ggtacagtaa aatatttgtt tgaactccct gataaaaaca
     8161 tgattgagac tgtactgatg agacaagaat atggcttgtc agtttgtgtg acgacacaag
     8221 taggatgtaa tatcggctgt acgttttgtg caagcgggct gctcaaaaag aaccgtgatc
     8281 tgactgctgg agaaattgtt gcacagatca tgatggtcca acattatttt gatgagcgca
     8341 atcttggcga acgcgtttca catgtcgttg taatggggat cggtgagcca tttgataatt
     8401 acgacaatgt aatggacttt ttgcatatca tcaatgatgc caaaggattg gcaattggtg
     8461 ctcggcacat tacagtttcc actagtggat tagcacacaa aatcaaggaa ttcgctaata
     8521 acggcttgca agtcaatctg gctatttcct tgcacgcgcc gaataatgag gtgcgaacat
     8581 cgatcatgcg gatcaaccga agtttcccaa ttgagaaatt gatggaagct gtggatgagt
     8641 atttagagaa aacaaaccgt cgaatcacgt ttgaatatat catgttgaat caagtaaatg
     8701 atagaccaga gcatgcgcaa caattagcag atctattaaa agataagaaa aaattagcat
     8761 atgtcaactt gattccatat aatccagtca gtgaacatga tcaatattct cgcagtccaa
     8821 aagctgatgt attgagattt tatgatgtat tgaagaaaaa cggcgtaaac tgtgtgatac
     8881 gtaaagaaca tggtacagat attgatgcag cttgcggaca attgcgaagc aagcaaatga
     8941 aaaaaacagt tgccaaataa tcgtatccta ctcgtttttt caattaccat aaaaggagca
     9001 gttttcttaa ttaaggaact gttcaactta aataagagaa aagattctat agcgaaagct
     9061 ataaagcttt ttttgacaag aaaaaccctc atcaagcaaa gaaatgtcct caatttgatg
     9121 acagcctgct tgatgggggt tttagcaatt atttaactga ttttcttata tccttgctgg
     9181 ctttcttgtg tagcatgata agtttctacg tcaagaatgg cctgtttaaa tttttctcgg
     9241 gtgatttcat aaggcacatg tttaatatca tttgttgcca tggctttatc taagattgct
     9301 tctaaatcgg tcgtgacatt gagattcatg tcggttaacg atactggaag ttggttcttt
     9361 ttcataaaca catagatttt atcaaacaaa tcgaactgct gatccatcat caataaggtc
     9421 agtacaccat aactgacaga tgctccgtga aggtatccct ccattttttc tagaacagtc
     9481 gtaccgtaat agaatgagtg tgccatagca gaattatagt tattgttaac taaaacagaa
     9541 accaatccgg tagtaacaat gatatccgaa acgacttgtt caattgcata tgagggacga
     9601 tcgtcggcac tatctttcaa tgcttgcgta ccataagtca agagacgatc aatgcacatt
     9661 tttccgattt ggattcctaa tctatccgtg tagcctagat catcgccacg agcagaaaaa
     9721 gtagattcga cttctttgga taaagcatcg ccaatacctg cccataagta tttatcaggt
     9781 gcttcggcaa taattgctgt atcaatgaag gtgtgtacag gtggttttga aggaaagaag
     9841 agtccgtcca ttacgccttc ttcgttatag atgacacata ccgcagtgac gggcgaacag
     9901 ttcgaaccaa tagtgggaaa ggtgaagact ggtttagcta gtttttcacc aatgactttt
     9961 acagtatcgc aagcacggcc accaccgact gcaaacagga cgtctgcttt ttggacactt
    10021 tcatgctgga tcaactgttc aatatttcca taagttgaat tacccccgta ccagagactg
    10081 gcgacaacct ctatttcctg tgtcaaagct acttttattt tgttttctgc ctttgaaagt
    10141 gcagtcttcc ctccaatcag cactactttt gtcccatatt ctttgacgat tccatttgct
    10201 ttttcatacg catctgttcc aatggtataa tttggtaaga aaacactttg actcatattc
    10261 atttccttct ttcttcgttg aaacgggtta aaattttaaa gagtgatcga tctgactgcg
    10321 gctgtagatg gagtagaggt gaacctaaga caggataagt gatgaataag gtggcatgaa
    10381 caccttgaaa tcatcaataa gtatcctaaa aacgaacaag tacaaaaaca ttgaaaacga
    10441 caataatgaa tttttgttcc tcttagtatt tctaccgatt ccctttgctt ttttgtaatt
    10501 atctaaaaat tctaaaaatt aagattatta tatgaaaaca ggttttattt gtcaattcat
    10561 aattggtttt ttttaaagca aaagataatc tatatcatga tgaacaaaca gagttttttc
    10621 ctccaattga tggctttcct gatctttcct attttgaata aagtgtttct gtataatttt
    10681 tttattttat aagtaagata aataatgaaa gaatagagat actgattggt agctaaagat
    10741 ttttgagcga gaacatttcg ttttttcaaa aggactgtta gaataagcaa gaacaagggg
    10801 gaagacgtat gataatcagt gaatttgacc gtaataatcc agtattgaaa gatcagcttt
    10861 ctgatttact gagactgact tggccggaag aatatggaga cagctcggca gaagaagtag
    10921 aagaaatgat gaatccagaa cgaatcgcgg tagcagcggt agaccaagat gagttagtag
    10981 gatttattgg tgcaatccct caatacggta tcacaggttg ggaattgcat ccattagttg
    11041 tagaaagctc ccgacgaaag aaccaaatag gtactcgatt agtcaattac ttagaaaaag
    11101 aagtagcttc cagaggagga atcacgattt atttaggtac ggatgattta gaccatggaa
    11161 caacgttaag tcaaacggac ctgtatgagc atacatttga taaagtggct tccatccaga
    11221 accttcgtga acatccgtat gaattctatg aaaaattagg ttataaaatc gtaggtgtct
    11281 taccaaatgc aaatggctgg gacaaaccgg atatttggat ggcaaaaacg attattcctc
    11341 gaccaaattc tcaataataa aaagaggttg tgacagaagt aatcagcttc aagaaataag
    11401 aaggaattta cgaaaattac ttcttgaatt tttgtgaaat tccaacttat ttccgaagaa
    11461 gctacttttg gaacaccgtg tac
//
LOCUS       DADVXM010000076        11479 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.080, whole genome shotgun sequence.
ACCESSION   DADVXM010000076 DADVXM010000000
VERSION     DADVXM010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.080"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(223..753)
                     /locus_tag="KB927_002168"
                     /pseudo
     CDS             complement(223..753)
                     /locus_tag="KB927_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
     gene            825..2117
                     /locus_tag="KB927_002169"
     CDS             825..2117
                     /locus_tag="KB927_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6841072.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSECRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
     gene            complement(2329..3171)
                     /locus_tag="KB927_002170"
     CDS             complement(2329..3171)
                     /locus_tag="KB927_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6841073.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
     gene            complement(3208..4674)
                     /locus_tag="KB927_002171"
     CDS             complement(3208..4674)
                     /locus_tag="KB927_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6841074.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            complement(4730..6574)
                     /locus_tag="KB927_002172"
     CDS             complement(4730..6574)
                     /locus_tag="KB927_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6841075.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            7176..8125
                     /locus_tag="KB927_002173"
                     /pseudo
     CDS             7176..8125
                     /locus_tag="KB927_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300609.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            complement(8170..8803)
                     /locus_tag="KB927_002174"
                     /pseudo
     CDS             complement(8170..8803)
                     /locus_tag="KB927_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(9063..9611)
                     /locus_tag="KB927_002175"
     CDS             complement(9063..9611)
                     /locus_tag="KB927_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841076.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(9612..10469)
                     /locus_tag="KB927_002176"
     CDS             complement(9612..10469)
                     /locus_tag="KB927_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6841077.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(10755..11042)
                     /locus_tag="KB927_002177"
     CDS             complement(10755..11042)
                     /locus_tag="KB927_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBB6841078.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKTLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            complement(11032..11361)
                     /locus_tag="KB927_002178"
     CDS             complement(11032..11361)
                     /locus_tag="KB927_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6841079.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
BASE COUNT         3499 a         2302 c         1810 g         3868 t
ORIGIN      
        1 gccgttctta tggacctgca tgatgaatgg atttattctt caagaaaata catcaatttt
       61 gataagtaga aatggtaaaa acattgtata gcattttaca caggagtctg gacttgacta
      121 acatttccat ttcatttacc tctttttcgt ttaattatac taaagttcta tccaagcgac
      181 aagctgtgta taataaaaat atacccgtgg tgctagttaa ttttaatacc ctaaagaata
      241 tctcaaagtc ccttcaaaat gttgctgtgc tcggcttaaa agaatactgt acgataataa
      301 tatgctttca aacttacttt ctagcccttg aatagaacgt gatttgaaat tttgaaaacc
      361 tagtctttcg agagaagaaa aaacagtttc tactgctttt ctttgtctag taagtaatcg
      421 atggtctatc ttccctagtt tatccatgtt ttttcgtgac ggaactaaga ctgtaatgcc
      481 cttaagggca agcttttcat ggattttatg gctgacatag cctttatctc caaggatatt
      541 tggaaggttt gcttcttccg ataaagtctc taaaactttc acatcatgaa cactaggatc
      601 cgtgattgaa taagtaactg gaaagcctgt tttagtgacg ataatatgaa ttttaagacc
      661 ataaaaataa gcgtttttcg ttgagttata gcccctacag ctctatactt tttgatgttg
      721 gtggatgaca ccagcatctt ttttattttc caaaacatat agaaaagaca ccttgaaatc
      781 ctttagaatt aatttggcga accaacccaa aaggaggaat caagatgtct tacactcacc
      841 ttatcaaaga aacattagat attctagact tatcagttac ttttaacgaa aattgtctca
      901 caaaagaaaa atacaaaggg caaatctgtc atatttatcg tggaaacttg atttatacag
      961 cccaagaatg catccactgt aaacaccaga ttgcttcaga tattgtgcgt tggggtacaa
     1021 caaccgtccg gttgttaatg aacgatgttt ctgaatgccg tacctacctc gaattgaaaa
     1081 agcaacgctt caaatgcaaa gcttgtcagc ggacctttgt cgcagatact tctgttgcga
     1141 aaaaacactg tttcatcagt gagaaagtcc gctggtctgt cgtgactcgt ctgaaaaaaa
     1201 atacctcaat gacagagatc gccgctcaga aaaatctatc ggtctcttct gtttaccgta
     1261 ttatgaagcg attttatcgt ccgttgaatc cttttcggac accgttacct aaggtacttt
     1321 gttttgatga attcaaatca gttcggggtg tttcaggtgc tatgagtttc atcatgatgg
     1381 atggacaaac acagcgcttg ttggacattg tcgagaaccg acaactgcct tttttaaaac
     1441 gttattttag tcatttttca cgagaaattc gtgaagcggt cgaatggatc gtgattgata
     1501 tgtacgctcc ttatgtatcg ctcgttaaaa agctgtttcc aaaagcacag ctgattattg
     1561 accggtttca catcgtccaa catattggtc gtacctttcg caatcatcga atcaaagaaa
     1621 cgaaccaact attaaaaagc aaagaacaaa aacactatca attaggtaag caattaaaaa
     1681 gatactggaa acttcttcaa aaagatgaac gcaagcttga ttatactcga cgcctttggc
     1741 gacctggctt caaagctcat ttaacagaga ccgatattgt ggatcgctta ctgaaaggga
     1801 gccctgcttt gcgtgtaggc tatcagttat atcaagactt tctttacgct gtaaaggaac
     1861 gagactacgt atcgtttgaa gaactactta ccaataatat catgcttccc gaaggctatc
     1921 agacgacctt gagaacgttc cagaaatttc tgccacaaat caaaaatgct ttacaacaaa
     1981 gttattcaaa tggcccactt gaatgtctga acaaccatat caaagtgtta aaacgaaatg
     2041 catatggctt tcgtagcttt tataatttca aattgcgcat catgattcgt catggcaacg
     2101 cattgatttt caactaaaaa agatcaagag gaactgatcc acttgatctc caattattct
     2161 aagatttctc tttaccaaca tcatttgaca aagagccgag attttttatt atcttacgtt
     2221 aatccttttt aaatgtctct tatagataac aaacagctgg aaatcacctt gtttttacta
     2281 taatccatct ctaaagattt taaaagcatc aatagtatta ctgagcgctc acccattagc
     2341 atgtttcatc aaccgattga tgtggacacc taggtataca acttcatcgt tcggaattgt
     2401 tttatgataa actttttcaa tgtagtcttt gatcttagct gcgctttcca tggcagacgg
     2461 gtataagatc cacatttgat tgtagaattc ttcctcacca tcatccaaca aagcatcaga
     2521 ataatatctt tctacaaaga aacgtacatg tgtaatgaag cgggcataat ggatcgaatt
     2581 agtatcgata tctttctgca acgaataccg gaccaaattg acgatcccgc cgatcatttt
     2641 tgcatacttg aatccagcgc cgctatcagg atcttccgat tgtgcattga tcaaatggaa
     2701 agcaatgttt gaggcttcct ctttaggaag atcaattcca tattgctcgt tcaaaagggt
     2761 gagtgcgtac ttcccaattt gaaattcttt gggatagtag atttttattt cccagtacaa
     2821 acggtttgca atatttaccc ctttttgtgc gcgttcaact gcaaaatgca ggtggtctgt
     2881 taaggttaaa tagactccag gattcagttt tttatctaat cctttttctg cttcaaaaac
     2941 gatagtacga gtgatttcaa aaaattcaat aggtatttct tcaactaact ctaatagttg
     3001 tgaagatttc ttttcttcaa aaggcagaaa tattttatct actttatctc ctgatatttc
     3061 atccccagct ttctgtccaa agcctatccc tttacctaat gcaatcattt ctttgccatt
     3121 ttcttcaaca agtaccacac ttgaattcaa tacttttttt attgaaatca ctcattatcc
     3181 ccctatcgct gcttaaaaag atcgagacta ctcgaataag gatgcaccgt ttgtttcgat
     3241 cacttctttg taccagttga acgaatcctt tttcaagcgg ttatatgtcc catttccttc
     3301 atcgtctgca tccacataaa taaatccata tcgtttagac atttgagaag ttcctgcact
     3361 aactaaatca attggtcccc agctagtata agctatcaaa tctacacctt catcgattgc
     3421 ttctttcatt tgttggaagt gtgctttaaa gtagtcgatg cggtacggat catggatttt
     3481 accatctact acctgatcga ctgctcccat accattttcc acaatcatca acggtacttg
     3541 gtaacgatca taaagttcga tcaacgaaat tttcaaacct tttggatcga tttgccagcc
     3601 ccaatctgtt gaaggcaaat gaggattctt aacccctaaa acagtatttc ccggtgtgcg
     3661 ttctgcgttt ggatcagctg attctgccat ggacatgtaa tagctgaaag aaacaaaatc
     3721 tacggtatgt ttctttaaaa tttctcgatc ttcatcttcc attttaatct gaattccccg
     3781 attttccaaa tccttttcga ttagagcagg atattctccc ttaacttgaa catctgcata
     3841 aaaattattt tctaagttct ttttcaaggt cagctcaacg tcttctggtg cgcaagttaa
     3901 tggataagtc atcaatttcg ttaacataca accaacttgg cttcctggaa ttttttcatg
     3961 agcatctttt gtcactaacg cactcgcaac aaattgatga tgcaatgctt gatagatatc
     4021 ttgagcttct tgaccttctg cgcttttctc ttggataatt ccagctgttg taaatggatg
     4081 acggtggatg ctgtctatct cattaaatgt cagccaatat tttacgtatt tgccgaagcg
     4141 atcaaaacaa acgttagcga agcgaacaaa atcatcaatt actcgacgct ccacccagcc
     4201 attatattta actgctaaag ctaatggcat ttcataatga gatagtgtca caatcggctc
     4261 aattcctaaa cgttgcattt ctttaaagac gttttcataa aatgcaaccc ctttttcatt
     4321 cggttccagc tcttctcctg tagggaacaa gcgagtccaa gcaatagaga ggcgcaaggt
     4381 tttaaagccc atttcggcaa ataaagctaa atcttcttta tagtgatgat aaaaatcaac
     4441 gccccttctt tttgggtacc atttatcaga tttgtcttca ctagcttctt ttatagactg
     4501 cagggtgaca tgcatatgag cagcaaaatc tttgttgtct aaatttggtt tataagtagc
     4561 catatccgct actgaaagac ctttaccgtc tacattccaa gcaccttcta cttgatttgc
     4621 tgctatcgcg ccgccccata aaaatccttt tggaaaactt gttgtgtttg tcattattct
     4681 attctcctct attccttcat tcaatatatt ttttttcact atcttgtgtt taagctatcg
     4741 gactgatagc taagagatca ctatcattgg ttaccaattt ttctaggtta aatgaacgga
     4801 tagtgtaatt atccttattg gttaccacac agataactgt ggggtcgaat cctgcttctt
     4861 tgattaaatc aatatcaaat gcaatcagct tttgtccttt ggctactttt tcaccagaac
     4921 gaacaaatgc ctcaaaccct tttccttcta actgaacagt atcaatacca atatgaaaaa
     4981 gaagttctgc accattagcc gtttttaaac caatagcatg cttcgtttca aataccattg
     5041 tgatttctcc atcttcagga gctactaata tcccttcttc aggaatgatt gctactccat
     5101 cacctaccat accactagaa aaaacagtgt cttttacttc tgatagtgag attacttttc
     5161 cattcacggg acttgaaaga acagcatctg aaacaacggc cgtttccatc ttagtttcaa
     5221 cttcattgac aacttcttta tctttataaa gaaccaacgc tgcagcaaaa gcaaccacaa
     5281 atgaaatccc cgatactgca aatgcccaaa ccagattcat tgggtcagct ttgtcagcga
     5341 acatcgtgat acttgcaatc ccaggaccca ctaaagcaaa ggcttgaagt gcaacgattc
     5401 ctgcaaatgc tcccccgatc aggctagaaa acataacggc atataaaaca cgtttgtgca
     5461 gaatcgttac cccgtaaaga gctggttcag taattccgaa taatgcagat atacccgcag
     5521 aaacagccgt agatttcaat tttttgtctt ttgttttgat actgacagca aagcatgcgc
     5581 cagcttctga aatattgtgt gccaatgaag ccgggagata aagaagttct gcacccaatt
     5641 cactcatgga tgaaacagcg taagggatca ttgctttatg catacccgtt acaaccatta
     5701 atggcagtac agctgctaag actccggttg caacccatcc aaattgattg tacaaagaca
     5761 caatgataga agagaaagct gttcctacat tataacctaa tggtcctaga agcaacaaag
     5821 caataggaac tgtaatcaat aagctcatca taggtacaaa gaaaatacga attggttttg
     5881 gtgaaacttt tgtaaaccat ttttcaagtt gagcataaaa taaaacagtt aagatggctg
     5941 ggaatacttg agatgcatac gctatattat ccaatccaaa agataagaat gtagcacctt
     6001 ccgccaacat agctgtcatt tcaggaagga tcaatgcacc gacagcagat actgcaacca
     6061 attgattgac tttcaattta ttagccgtag tcattgccac cagaataggc aagaaataaa
     6121 gcggtgcccc gccgaccaaa tttaaaatct gataggtttg agattggtca ctaatcagcc
     6181 ctaagataga agctagtagc aacaaggact tcaatactcc tccacctgca atcgcaggaa
     6241 ttaaaggttg gaaaatagaa ataataaaat ctaatagaac tgaacctaat ttttgttttt
     6301 gttttggtgc ttcttcagta tttgaaacat tgtcacctaa taacgctttc acttcatcat
     6361 acacttcaac aacatcgttt ccaatgatta cttggcattg cacattttgg cgaacgccca
     6421 taacgccatc cactttttct aactggctca tatttacctt gctgttgtct tttaacgtaa
     6481 aacgtaaacg agttgagcaa tgctccaaat gggatatgtt ttcttcccca ccgatgtact
     6541 gcaatacttc ttctgctgtt tgtttgtaat tcatggtgtt tccctctttt cttttttgag
     6601 tgatgaactt ttgagtcgaa gtggccatcc tcaacacaaa aaacaggcag aaactaaata
     6661 aattgacaac aaggcaaacg tgtattgaaa cgcatacatt gttattcaac ttatttaggt
     6721 cctgcctgca ttaccagtca catgcctgtt taagttatat tcaatttaac atattagaat
     6781 gtaaacgtaa ataataaaat gattttttaa tcattttttc attttattcg ttcaatatag
     6841 ttttcgtgtt ctaaaagttt tgtctttttt ctaagaatat cttccaacat atataactct
     6901 tattctcttc tatcttctag cagatgttct gtctttttaa gacctagtat aaaaagaatg
     6961 ggttcatttt ttctttcttg caggatgagg ttttttatat aaactttatt tgatataaag
     7021 aaaaggcatt cataattgtg ctatactact aaaaaatgat aatacagtga attagattag
     7081 cgctttatta aattaagagg acagcatatc gatattgctt cctttttttt gctatttatt
     7141 taagggatag aagtttagaa aggactgttt ataagatgaa aaatgatata gtgacttatg
     7201 caaacacaaa atgtgaagaa attggcatca gtaatttaga agagtgcttt tttgacacaa
     7261 atgacctgtc gcaattttta agaacgggaa gaacaaatgc cagtaaactt gccaatgact
     7321 tagttgcaaa gaacgttcta tttaaaatca atactcgtcc agtgttattt gccatcaaag
     7381 agcgctttga agagcacttt ttgattccgg taaaagatgt atacgaaagt atatctgaat
     7441 taaaaacaga cttggagccc aattctacag attccattct acaaaagatg attgggtatg
     7501 atatgagctt atccgatgcg gtggaacaaa tgaaaactgc tgtcttctat cctggaagag
     7561 ggcttcctat gatgatcact ggagatactg gagttggaaa aagttttttt gttcatactg
     7621 cttatcagtt tatgaaaaaa gtgaacgtta ttcatgagaa tgctcctttt aaagtactta
     7681 attgtgcgca ataccataat aatcctgaat tattgtcggg gatactattt ggctatgtta
     7741 aaggtgcttt taccggcgca gatgaagatc gaaatggatt gttgcaagat gcagacggtg
     7801 gagtactgtt tttagacgaa gtacacagat tgcctcctga agggcaagag aaactatttg
     7861 tttatatgga tggcggaact tattctagag tcggtgaaac tatccatcac gcctccaatg
     7921 tacgtttagt ttttgcgact acagaaggca aagaggattt tctggaaacc tttatgcgaa
     7981 gaatccctat acatatccat atcccaaata ttgaggaacg aggtatttta gaaaaaaaca
     8041 aattatcgaa aatactctct ttagcgaaag caaaaacttt agcaaggcta ttgatgtttc
     8101 tcctaaagtc actagtgttg cataaatata gtcagaatat tctgaattat tattttcttg
     8161 aaaaaagtaa aaaaaatcgt atcccaaact ttcatctaca tttccagaaa gatcttcatg
     8221 ttgataatca attcctgaat caatgaccgc taccttcaca tccttagaac ccttggtttc
     8281 ttcccaagcg gatggcatgc taatctctct taaattagct tgtttactcc aattaggatc
     8341 gttatcgatt tcctaaagaa tcagttgtat ttggctcctc aacatcattc aacggctcta
     8401 gttcaaccac atagtttggc tctgcataat tgaccatatc agaagcatta aatgttctta
     8461 ctgcctcttc cacactaatt tcttcgttca atttcactaa taatacttga tctcgcttat
     8521 tataatcgct ttcatttgtc ctaagagtca aatctttttc caccataact tttacaccca
     8581 ataaattttg cggtttattt ttctctgttg aaattctttg tgtagccttt aaactgacaa
     8641 ttagctcatt gggtacatac tctatttgag agtcatctaa ttggctcata atcctttctt
     8701 tttggttagt atctgcagtt acttgtttag tatgagccat gaacccaaac atactcaccc
     8761 caacaaccaa tcctaaatat attttctttt taaacttttt catctacatc tcctcctaat
     8821 agttttattt tagagttagc tctattactt atttactaac tcaacaacag attatcatac
     8881 acttattaat gaaatcacaa tatctcatta aaacacaccc taaaatcata accgttccta
     8941 tgctcatttt ttggattttt taatcacgta accagaaaaa taaatcccct ctatttcacg
     9001 caaatcaaag aagaactaag taactaccgt ttaaaggtag ttacttagtt cttctttgat
     9061 tattatctaa ctttattatt cattccccac cctttgcgca gtgagtcttc ggtatcttgt
     9121 tttatctgac tggtagttct tattatttct ccacgatcat ctaattctgg aacaattgga
     9181 tatttttctc tgaacaagtc tagttctttc accacgtcat taaacaaatc ttgtttatct
     9241 tcttgcgtaa gattctgttt aatatactca tctaaagctt ttctaagcaa ttcatctctt
     9301 gtcatattag tctcatactt ttctactaaa actctggaag tcgcatttaa caaagtcgac
     9361 agttttaaag gatgcttggt ggaataaacc ttatcaaact ttctgattgg tgcgccaact
     9421 ttttttgttc ttcctctact ctgtctttca acattggagg aagtttttat ttcttgaact
     9481 tggtgcactt ctaattgctt attttcagat ggtgtaattg cttgctgctt tttctttgct
     9541 tctgcttctt tttttatttt ggcgagtcct ttgttgttcc caaaaatatc aagtcctttg
     9601 atgtcagcca attactccac ctccgcatac caattctcgt gttcttccaa ttctttcaaa
     9661 atactgataa ataattcgtg gcttttgcga tcccattgtt ttaagagacc tttctttgtc
     9721 ttctccatcg taatacctga tccgtcgtat cgttttaagc gcgcattttt gagtacaaca
     9781 tttttaatca aatgttcccc ataaatctct tgggcttgtt tatacatttc ctgatctact
     9841 gcgtcaccgc tttccaacat gaaaggaata acaccagcaa catataaatt tgtatcaaat
     9901 tctttcacaa aaaagtccat atactcaaga tattgcatcg catttctcat cgattttact
     9961 tgggtctgta agacgacgat tgcccaatcc gcaatgtaca tcgcggattt actatataca
    10021 gaaatagaag gtgggacatc taaatagatg acgtcaaact catcaaataa tggttctagc
    10081 ttttctttca tatatttgaa ttgggataat gaatcattat attggtcttt gatccaatca
    10141 tcatacattt caaaggacat gtctgctgga agtatataga ggttattgat tactttatag
    10201 acagcctctt taggtggaag attgtttatc aacacgtcag tcacagtatt ttcgtaaaca
    10261 atcggttcac cttctccgcc tccttcttcg ttagtgaagt tcatatgcgt taagttcatc
    10321 acatcagaag tatttccttg catatccaag tcaattatca aggttctttt tccttcatta
    10381 actgctgatt caaaccctaa catttgcgcg cacgtacttt tacctacgcc acctttaaaa
    10441 ttaccgatta catatttttt cgctaccacg ttcctacctc ttttctttta gcaatattca
    10501 tttgatacta ttataacata tttattttta gttactacca aaaaaaagat atatatgtac
    10561 taccttataa ttaataagta aaaggtagta cataaataag gaaaagctga aatatattga
    10621 tttatagctt tcctcaaagt aatgacgtta tttaatttat cgagaagcag agaatactcg
    10681 cgactttagt catgtagatg aatcagatct tcgataaaaa agaagccgtc cttcttaaga
    10741 acgacaacaa atcactagat taattttttc aactgttcat aaaagttttc atgcgttcca
    10801 cataacaata ctggaataac cttgttttct ataatctcgt aagctactct atatgttgtg
    10861 cccgcatatt tgaacccact agaccaaata cctgataaat ccccagtttt ttgttcaccc
    10921 ttatatggat caatcgcaat ttcatcataa attaaattca aaaatttttc tttcaatgtc
    10981 ttctctttta gcttttttaa atacttaatg acatgttttg aaggaacgat ttcataagcc
    11041 aatttctgtt gccaactcct ctttagtcat tactttagaa ttagtaagtg tatcttcagc
    11101 aatatctcta aaggaagaat gcattttgtt ttttctattc ttaaattcta caagaatctc
    11161 atctttatcg tagccttctg caattatatc agacaaaata tcttcgctaa aatcataaaa
    11221 ttctttttgt ggttcaacaa attcataaag aataccattc tctaccaact ttgcttcaac
    11281 ttcgactcca ttaggaacat taaaatcttt aggtactgtc aacatgattg aattgccttg
    11341 ttttcttgtt tttgtaatca tttaaatccc tcatttctaa cagtatgtaa ttacttagta
    11401 aatacattat accacgagat aatgtattta caagtaatta ctgtgactcg taatgcgtcc
    11461 ttgctgaata aatttcaac
//
LOCUS       DADVXM010000077        11262 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.082, whole genome shotgun sequence.
ACCESSION   DADVXM010000077 DADVXM010000000
VERSION     DADVXM010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.082"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            38..337
                     /locus_tag="KB927_002179"
     CDS             38..337
                     /locus_tag="KB927_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6841080.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            410..1771
                     /locus_tag="KB927_002180"
     CDS             410..1771
                     /locus_tag="KB927_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBB6841081.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1793..2053
                     /locus_tag="KB927_002181"
     CDS             1793..2053
                     /locus_tag="KB927_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841082.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2067..2819
                     /locus_tag="KB927_002182"
     CDS             2067..2819
                     /locus_tag="KB927_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBB6841083.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2913..3518)
                     /locus_tag="KB927_002183"
     CDS             complement(2913..3518)
                     /locus_tag="KB927_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6841084.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3571..4545)
                     /locus_tag="KB927_002184"
     CDS             complement(3571..4545)
                     /locus_tag="KB927_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBB6841085.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4923..5642)
                     /locus_tag="KB927_002185"
     CDS             complement(4923..5642)
                     /locus_tag="KB927_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6841086.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5769..7040)
                     /gene="celB"
                     /locus_tag="KB927_002186"
     CDS             complement(5769..7040)
                     /gene="celB"
                     /locus_tag="KB927_002186"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBB6841087.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7193..8590
                     /locus_tag="KB927_002187"
     CDS             7193..8590
                     /locus_tag="KB927_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6841088.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8671..9111
                     /locus_tag="KB927_002188"
     CDS             8671..9111
                     /locus_tag="KB927_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6841089.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9259..9585
                     /locus_tag="KB927_002189"
     CDS             9259..9585
                     /locus_tag="KB927_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6841090.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9586..10335
                     /locus_tag="KB927_002190"
     CDS             9586..10335
                     /locus_tag="KB927_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841091.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10415..10870)
                     /locus_tag="KB927_002191"
     CDS             complement(10415..10870)
                     /locus_tag="KB927_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBB6841092.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
BASE COUNT         3575 a         1963 c         2310 g         3414 t
ORIGIN      
        1 tattagacaa atgatatttt acgaggagga agaaaaaatg aaaaatcggt taattgtcgc
       61 atgtggaagt ggagtagcaa cgagtcagac aatcgctagt aagatccaaa gtatgttaga
      121 agatgacggc atcgcatttc ctgtagaagc agttgattac aaatcgattc aaaatgagct
      181 tctaactgct ggaatctatg tgtatgtcgc acaacctgat gaggaagtac ttgaacaagc
      241 aaaagatttg ggtattgaag tatttccagg aattccattt ttaactggaa tgggtgtaga
      301 acctatttat gacagtatca aagagttagt acagtaaagg aggattgttg gataaaaaag
      361 ttggttcata gttttattta ctatatttag aaagaaagaa ggtttattta tggaagtttt
      421 ccaaaccatt atcaattatg ttttgaactt aggatcagcc atttttgttc ccctgattat
      481 tttgatactt ggattgttgg cagggatgaa attaaaaaaa gcattcatgt ctgctttgac
      541 tttagggatt gcttttagcg gaatgtctat ggtcattggc tatatgtcta acgcagtaag
      601 tccagcatca gaagcattgg ctaaaaatac gggaatcagt ttgcctgcac ttgatcttgg
      661 gtggacaggt gcagcaagca tcacatggtc gtggagttat gcttttatat tttttgcagt
      721 aacgattggg gtcaattttg tactgttact ttttaattgg acgaagacgt taaatgttga
      781 tatgtggaat gtttggggga aagctttaac tgcttattta gtttattatg tttccggtag
      841 tttggctgca ggctttctta ctgcaatggt ccaagttata ttggaattaa agcttggtga
      901 tatgtttcaa aaacatatac aagatctcac agggattcca ttagtaacag tgactcattt
      961 tatgacatct gccgctgtct tgttgctgcc tttcaatatg atcatggata aaattcctgc
     1021 tttaaataaa cgagcggata cgaatgcatt gaagaagaaa attgggatct tctctgaaaa
     1081 ctctgtaatg ggattcatta ttggattggg gcttggcttt gctgctgcgt atggcgtttc
     1141 aggttctctt aatctagcga tccaaacagc tacagcatta agtttgtttc ctatgatctc
     1201 taaaatgttc atgcaatctt tgtctcctct agcagacgct atgtcagaat ttatgaaaaa
     1261 gcggtttaag gatcgtgaag tatatatcgg attggactgg ccgatattag ctggtcgttc
     1321 agaaatttgg gttactgcta ttttacttgt tcctgtgttt attggttatg ccattatttt
     1381 gccaggaaac caagtattgc cattagcagg gattatcaac tattcgattg cggtcggcgg
     1441 attactttta acaggaggaa acttggctcg tatgctgatc ttgggaatca tcactatgcc
     1501 tatttatttg tacggggcca cttaccttgc gccaatactc agtgatttag cagaaaaaag
     1561 cggagcagtc gagggaatca agaaaggaca gttgatcaca tggtcatcca tagaagggcc
     1621 ggagttcagg gttttatttg cggaggcatt taataggaat attctcgcta ttgtaggatg
     1681 cgtgattttt ctaggactgt ttgttctact ttataaatat atgataaaag cgaaagtacc
     1741 gagtgaacgt tatgctgaac tacaaaaata gcattgaaat ggtgggaaag taatgaaaag
     1801 agaagagaca gataaaataa aatggacagt cgctctttgt ggtacacttc tgctatttct
     1861 atatggactc tttactcaga atatcatcat caatctattg gtcatttttt tcgcactagt
     1921 gatctataaa tatggaaatc acgttttatt cagagagtac gatgaaaaaa gaaaacggaa
     1981 aatagaagaa tcaatgaaaa taaaagaagc taccaaagaa atattgagag aaaaaagttt
     2041 tataaaaaga taatggaggg gtcattatgt cagatggacg tatgttattt gagagagaac
     2101 gacaggacat ggcacgtatc gtaagagtga ttttcgaaag gaaaaacaca aatgtcgcag
     2161 gagggaattt ttcctttaaa accactgatg atcaagggaa agactacatc atcatgacgc
     2221 cgaccatgat gtcagaagcc tatctaggag agatttctcc tgcacaggtt ctagtagtag
     2281 aaccaagaac gcgtagaatc gttgacggag tcggtcattt aactcgtgaa atcaatatgc
     2341 atgaagcgat gtatgagact aatccagcta tcaaagctgt cctacatgct catgcgccta
     2401 atgcaatgtt ctgggcgact actgggttgc ctatgcctaa tttgacagaa gccacagcta
     2461 aagtaaaaga gattcctgtc atggactttg agcctaattg ctctgaagaa cttgctgaat
     2521 tgacaagcga ctatgtaaaa aaacagcatc tcgaattacc gcatatgttg ctgctcaact
     2581 ctcatggcgt attgatcaac acaggtggag aatcaggaat cgaagctatc cataaagcac
     2641 tgcaaatcct tgatacagtt gaatggaatg cagaaattgc ctacaagcag acgatttttc
     2701 aagcattagg gattactgac ggtttttatt caaaaggtga gaaaatcggg ggattggaag
     2761 agttgaaaca taaaacggct atttataata aatctgttat tgcagctggt ggagactaac
     2821 ctatctgaca caaaaaacta cgactttcac aaaatctgat ccagatcgat atctgcttca
     2881 ggttgtatta tgtaagtcgt agttcttttc ttttatttag ttaagaggtg gtctgtccat
     2941 tccctcgctt gcttgatttc gtccatcgtc aactgatgac ctgttacagt tagctgaata
     3001 gtcacatttg cttggcgtgt ttcgaattga tcggccaatt ctttaaagga agcaggggaa
     3061 acgattggat cgttatcacc ataagaaatc cagacggttt tatcctctaa tgtggaacgg
     3121 ctttgatgaa cacctagaga catcggatgg aaaaacaacc ctttatttag ctcggtctca
     3181 cgctccaata ataaatgagc agcgatgttt gcgccatttg aatagccgac aagcagccag
     3241 tcacttaacg gtatcagttc tttttcgctg atttctttga ttttttcatg gagtttatct
     3301 gtttcttttt ccaaactgtc caggtcgaat tgattcaatc cattacgctt gaaaaaacga
     3361 ttcatcccat cttcttggac cgtgccacga aaagaaagca atgtactgtt tggtgcaaga
     3421 aagtgagcga tatccagtaa agaatgttca tcgccacctg tgccatgaag taagatcaaa
     3481 tgcttgccac ttgttccttt ttcaaaaatg taggtcattt tgttccctct tttctgtttc
     3541 tatagatgca aatgaagtag catgaagaga ttattcacgt tttttatttg catcacttgt
     3601 atcgaaagga cggacataag cttcaatggc ttcacgacgt tcttctaaga atggaggaag
     3661 agatagtttt tctcctgctg attctgctgg ttcatcttca aggaatccag gaccatcagt
     3721 tgctaattca aacagtacgt gatgagcggc taggaagtac tcagattgga aatagaaacg
     3781 atcgacgaaa ccagaatttg gcaattcaat cttattgatt acttgaatcc agtattccaa
     3841 tgcttctttg tctgctacac gcaatgctaa gtgatggata tttccaaatc cttcgattgc
     3901 ttttggcaag tctgtccgat gttcaataat gatgcttgca ccatttcccc cttcaccgat
     3961 ttcaaataag tagaaatctc ctgaatggtc tgtttctttg aatcctaaga ttttttcaag
     4021 aatcaagcgg atatgctcta attgactgac acggacaaag acaggtccaa gtcctgtgat
     4081 cgcaaactct gtcggtacat tgctgttttt ccaaggaatg ccagctgcta caccttgatt
     4141 gttttcgtca gagatcaatt gataatactg attatcgaaa tcttcaaatt cgatatattt
     4201 tttgccgaaa cgttcattga ttgctgaatg agtaacgtca tatttttcaa aacgttccaa
     4261 ccaaaagtct aatgctgcgt cacttggcac acggaaagaa gcacgagaga tcgtatctgt
     4321 tccttttttt ccttttggct gatttggaaa atcaaagaaa gtcatatctg ttcctggcgc
     4381 accagtatcg tctgtaaagt aaagatggta agtttcgatg tcatcttggt taactgtttt
     4441 tttgattaag cgcattccta aaatatctgt aaaaaagcgg tagatttttg tagcgctaga
     4501 tgtcattgct gtgacgtggt gaattcctct gatttgtgta tccatgataa atttcctcct
     4561 gttaacttac aaaaagtaag tagttgattt agacatagta tagagggtgc atctctattt
     4621 tgcaattaat ttgtcttcta aagtatcagg aaggaatcaa gaatggaaaa gaggagggac
     4681 ggatcaataa aataaaaaga cttacgacta gctgtatcga tttcaaaaaa actagcttta
     4741 aaaagctaac tttagaatca ttacgggtgg tcataagtct ttttatgctg agttattttt
     4801 tcatttttga gctaatgctt aggatagaat agaatgttga tttcacgatc tcttcttgtt
     4861 acttgaaact gcttaccact gtcacgatct cttggtaaac ggctttttca caacctcttt
     4921 ggttaagttg aacgcacatc cagcacagaa tagttccgaa catcaaatcg gtttcggctg
     4981 gaagaatatt caatcggctg tccatctttg agatagacga cttgctgaac ttccagtaca
     5041 ggatcgtttt ctgcacagtt caaatattgc tgatcatatt catcactttt atctgcagaa
     5101 atagcacgat aagcccctgc aaaatggaca ttcaattctt gatgaagatg atcatagata
     5161 gaggctaaca aatgttcttt ttttaaaccc ggcacaagat ggactggcat aaaggtatgc
     5221 tctaaaacat atggctcgcc atctaagatc cttaaccggt gaatattgta gacaggttgc
     5281 tcggcatcga tcatcaatcg ttcttggata tattgattag ggaattcaac atcaaaatga
     5341 atgatttgac tcttcaaaga acgatgtctg cgtttcattt ggagactcaa accttcatac
     5401 tcgttagcgg gcgatgtgtc tttttgcata aatggatgat tcaagatttt cgttcctgat
     5461 cctcgctgcg aatagacaag tccttccatt gctaagatat tgatggcttt tttgattgtc
     5521 atccggctcg caccaaattc ttttaccaag tcgacttgat taggcaaaaa actatcgaga
     5581 ggatactctt ttgaacggat acgttctctt aaaatatttg cgatttcttc gtattttggc
     5641 acgttattca cctcttctag agtataacga aagattatgc ttccgacaac tcgaagtagc
     5701 atctggaaca ttgtttattc gaaaaaagag gtcatgacaa gtttttgtca caacccctta
     5761 atgatctatt aagcaatatc taaatctggt tgtttatcta gtactttcag gaatgggtac
     5821 cagataaagg caacgatgac aaagtcgatg acttgcagca taccaccaag ccatgaattt
     5881 gttgctaaga caccgcttgc aatgattggc acagtccatg gaacagagac gccagttggt
     5941 gcagggacaa gtccagcagc cattaccaaa taattgaacg tcgttacgat tagaggtgcc
     6001 acaacccaag gaataaggat tgttgcattc aatacgatcg gtagaccgaa gatcgctggt
     6061 tcatttacat tgaaaatacc aggtgctaaa gctaatcgtc caacatcacg atactgtttc
     6121 tttttaagaa caaaggccat caataaaacg acagctaaag tcattccaga gccaccaata
     6181 ccaacagtga aggtttccat gaatggtttt gtgatgatgt gtggtaattc ttttccatgt
     6241 tgataagctt ctaagttatc aagcatcagt gtattccaaa tcgggtccat tacagagttg
     6301 acgatgattt gtccgtgaag tccgaagaac cataagaatt ggacaaagaa caaagcaatc
     6361 aatgttgcag gtaaactact tcccaaacca gttaatggtt tttggatcac ttcataaacg
     6421 acgtcatgta agttagcatt gaaaatacca gtcatcacag cattgattac taagaaaata
     6481 gttagtgtca ctacagcagg gatcaaagcg gcaaatgatt ttgttactgc aggcggaact
     6541 ccatcaggca ttttgatctg ccagccgcgt ttcgtgattc tgcagtagat ttctccagcc
     6601 aagaaagcag cgatcattcc aatgaacatt ccttttgcgc caagacgatc aagtgaaagc
     6661 acaccagtca catcttcacc gccagcggtt ttcattgcaa aaggcgtaag aatcaagaag
     6721 ctggcaaaag acacggcacc accgaaaata ccttcaacgt cataagattt tgataaataa
     6781 tagccgatac caaaagtaac aaaaaccgac atgatgctca ttgttgcatt ttgcccatta
     6841 ccgaataaat tcgataaagt tccctttgtt gcgtcactga aaaaaggcaa gttattgata
     6901 acgacaacga tcgaaccgaa catcgttaaa gggaaggaaa gcatgaaagc atcccgcagc
     6961 actgtaaggt aacgattttg ccctaataaa ttagctaagg gcatgatttt ctcagaaagc
     7021 ttgtccataa aaccgttcat ttttattcac ctcaaattta tttgcaatcg attacataca
     7081 aagtataacg ccaaaaaatt taaatgtcta gtcattttca taaaaagtat tgatttattt
     7141 tttagggttc gttatgatta cggtatcaag aaaaaagaga ggaagtaaaa aaatgaaaac
     7201 ctacacattc ccagaaaatt tttggtgggg ttctgctgct agcggaccgc aaacagaagg
     7261 aagagtaagt gatgatggta aaggagaaaa tatttgggat cattggtatg aattagagcc
     7321 tgaaaaattc ttcgatcaag taggacctga aaaaacttcg caagtttaca caaaatacaa
     7381 agaagatgtt cagttaatga aagaaactgg ccataacaca tttcgtacat ctatccaatg
     7441 gagtcatttg attccagaag ggacaggtga aatcaatcaa aaagctgttt ctttttatcg
     7501 agattatttt actgaattgc tggataatgg tattgaacct tttgtgaacc tttaccattt
     7561 cgatatgcca ctaccactgc aagaaaaagg cggatggtta tcaagagaaa cggtcgacgc
     7621 ttatgtttct tatgcagcag cgtgctttga actgtttgga gatctggtca aaaaatggtt
     7681 tactcataat gaaccaatcg tacctgtaga aggaggctac ttgtatcaat tccactatcc
     7741 aaatcatatc aatatgaaag aagcggtcca agtaggctat catgagaatc tagcaagcgc
     7801 aaaggtaatc aaagcctacc atgaaggcgg acatgatggt gagatcggaa tcatcttgaa
     7861 tctgacacca agctatccga gagatgaaac gaacccagaa gatgtaaaag cggcgaagat
     7921 cgctgacgca ttcttcaacc gatcattcct tgaccctgca gtgaaaggag agtttccaca
     7981 agagttgatc gaaattgtca aagaattggc tataatgcca gagatccatg aaggagacct
     8041 agaactcatc cgtgaaaaca cgattgacct gctaggaatc aattactatc agcctcgtcg
     8101 aatcaaagca aaagaaactc caatcaatca cgaacatagc cccatgccag atgattattt
     8161 tgataattac gacatgccca ataaaaaaat gaatccatat cgtggatggg aaatttacga
     8221 aaaaggaatc tatgatattt taacgaatac aagagaaaac tatggtaata tcaaatgcta
     8281 tatttctgaa aatgggatgg gggtcgaagg agaagaacga tttgttaaca gcgaaggaat
     8341 tattgaagat gattaccgga tcgagtttgt tacggatcat ttgaaatacg tccatcaagc
     8401 aatccaagaa ggaaccaatt gtgtgggtta ccacatgtgg acatgtatgg acaactggtc
     8461 ttggacaaat gcttataaga atcgctatgg ctttatcgct gttgatttgg cacaagacgg
     8521 taaacggacg atcaaaaaat caggtcgctg gtttaaaacg gtctctgaaa aaaacggatt
     8581 tgatgcctga tattttttga taaaacgttc acaaaatgtt tgttctaaca ctgtaatcgt
     8641 gctacactaa cagtgaagga ggcgtttaca atggtagata cttatcgtaa tattttagta
     8701 gcaattgatg gttctgaaaa ggcagaaaaa gcatttcttg aggcaatcac gattgccaaa
     8761 cgaaatcagg caacgttgca catcctgtat gtcaatgaag taacaggcaa ttactttggt
     8821 gattttgcat ttgttacaac aagccttcag gaagaattgg atgaggttgc ggaaaaccag
     8881 atgaaagaac atcgaaactt ggcaattgaa aaaggcctga cagatatcga gacatatgtt
     8941 ctttacggtt atccaaagac actgattgct aatttccatg aatcgaaaga accaatcgat
     9001 ctgattgtca tgggggcgac aggtctgaat gcggtagaac gtgcactagt aggttccact
     9061 acttcctatg tagtcaacca cgcatcatgt aacgtcatgg ttgtaaaata aataaattaa
     9121 gggaacagaa agcaaaaaag cataacgctt cttttgcttt ctgttccttt tatttttttg
     9181 taaaaaatta ctttacctga tgaagtaatc atgctattct aattacaacg acagatggag
     9241 taatatggag gaaagaaaat gatttcaagt gatggaatac gcggatacaa tgatgcgatt
     9301 attttatcga tccttaacaa aaacgattct tatggatatg aaatttctaa aacgattcgt
     9361 gagaggacaa atgattccta tgtgatcaaa gagacaacac tttactccgt ttttgcccgt
     9421 ttagaaaaga atcaactgat tgtttcgtat cctggagaag tgactcatgg aaaaaagcgg
     9481 acatattata aaatcactga aatagggcgt aatcttttag aagaaaaaaa gcaagagtgg
     9541 ctgacgacga aagacgtagt cgatcaattt ttggagggaa attaaatgga tacaatccgt
     9601 aattatttag acagtctttt tatcggagta cctcaaagta ccgagataga taagctgaaa
     9661 actgatttgt tggcaaatat ggaagaccat tatcatgaat tgatgggaga aggaaaaaat
     9721 gaacaggagg ccatcggtac agtaatttcg acatttggtt caatcgatga attattagaa
     9781 gaactagatg tcgaaaaaaa acatcaagct gacgagacgg aaacaaacac agcttctatt
     9841 tatttaagcg aagcagaaaa ctactggaaa gaatacagag cggcaagtct ccaagtggca
     9901 tcaggtgttc tattcattag cttatctttt gcaagttttc ttttcttttg ttcagcagga
     9961 tatgtgttca tgggtatttc ttgtctgatt ttcggtatag cattagctgt cggttttttt
    10021 attgcttctg gtatgaaaat cacacgttta aatcactttt tgcaccatcg gaaaatacct
    10081 gaaaaagtat tagcagaagc aaaagaaaaa gaagaagagt atcagcgaag ttttggcttc
    10141 tcactgattg caggaattgg attatgtatt ttttcacttt tcccactttt ggcttcttta
    10201 atgtggtata tggatggtag tatcggtgcc tctatatttt ttgttacggt aggaacgggt
    10261 gtcttcttga tcatttatgg cagtctagtc cgtcattctt atcgtcaatt cactcaaagc
    10321 gcttattact ggtgaatgta ttcagatttg taaaaatatt ctatttatcc ggcgtagaaa
    10381 aaaagactgt gacacgcttt tgtcacagtc ttttttatat ataataattt aaaaattcat
    10441 catctaaatc cgtagaattt tctagattgc ttacccatgt aaaatcgtta tagacagatt
    10501 tcagttgact tctgcgccat tgtacaggga taaaaagacg catgctatct tcattgaatc
    10561 cgactaataa tttctttccg tcagtaatga tgggacgttg taacaaagta aaatgcgaga
    10621 cgatcagatc gacaagctct gaggtcgtac attggtcgat ttggtctttc aaatttttat
    10681 aatcaatcga gcgtttagct aatagatcgt caaatccgtt ttctgttaat gacaataaat
    10741 aaaatatctc tttccttgtt aaaggctgtt taggtgtgaa aattcgttct ctgtaaggca
    10801 tttgatggtc tttcagccag tttgccatca gatggtaact atgtgtgcga gaagaataga
    10861 tcgtaagcat aaaaaaactc cttaaatagt ccattaattt gttagatctg ttgagataaa
    10921 taataggtaa ggagctgtgc ataagcattg atcaaaacaa cccaaacatc attagaaata
    10981 actttctaaa gtcttaaact tgcgacgaga aacaactaga ctaatagaaa aaatgtctta
    11041 gccatttggc ttcctgtttg tttttttgct tatgctgcag ctcctcggga aagggttcta
    11101 acaatttgaa gaaggttgat gattgatcta gtttaaattg tgtgaaattt gaaatctggt
    11161 gtttttacta gatgaatcac ctaacaacta tgattataac ttatagaact tctgttttgc
    11221 attcggtttt gttatagttg ttataaagtt ttattttatt ac
//
LOCUS       DADVXM010000078        11166 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.083, whole genome shotgun sequence.
ACCESSION   DADVXM010000078 DADVXM010000000
VERSION     DADVXM010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11166
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.083"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(198..1046)
                     /locus_tag="KB927_002192"
     CDS             complement(198..1046)
                     /locus_tag="KB927_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6841093.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1045..2112
                     /gene="gnd"
                     /locus_tag="KB927_002193"
     CDS             1045..2112
                     /gene="gnd"
                     /locus_tag="KB927_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBB6841094.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            2114..3115
                     /locus_tag="KB927_002194"
     CDS             2114..3115
                     /locus_tag="KB927_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBB6841095.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3112..3396
                     /locus_tag="KB927_002195"
     CDS             3112..3396
                     /locus_tag="KB927_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBB6841096.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3429..4226
                     /locus_tag="KB927_002196"
     CDS             3429..4226
                     /locus_tag="KB927_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6841097.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4240..5073
                     /locus_tag="KB927_002197"
     CDS             4240..5073
                     /locus_tag="KB927_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6841098.1"
                     /translation="MEILSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5091..5948
                     /locus_tag="KB927_002198"
     CDS             5091..5948
                     /locus_tag="KB927_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6841099.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            5970..6479
                     /locus_tag="KB927_002199"
     CDS             5970..6479
                     /locus_tag="KB927_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6841100.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6516..6917
                     /locus_tag="KB927_002200"
     CDS             6516..6917
                     /locus_tag="KB927_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841101.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7029..7382
                     /locus_tag="KB927_002201"
     CDS             7029..7382
                     /locus_tag="KB927_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841102.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7416..7859
                     /locus_tag="KB927_002202"
     CDS             7416..7859
                     /locus_tag="KB927_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6841103.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7876..8961
                     /gene="uxuA"
                     /locus_tag="KB927_002203"
     CDS             7876..8961
                     /gene="uxuA"
                     /locus_tag="KB927_002203"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6841104.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            8954..9667
                     /locus_tag="KB927_002204"
     CDS             8954..9667
                     /locus_tag="KB927_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6841105.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(9874..10023)
                     /locus_tag="KB927_002205"
     CDS             complement(9874..10023)
                     /locus_tag="KB927_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841106.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            10419..10619
                     /locus_tag="KB927_002206"
     CDS             10419..10619
                     /locus_tag="KB927_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6841107.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         3735 a         1748 c         2412 g         3271 t
ORIGIN      
        1 tactaacttt gttatcgcat ctaacaagta actcgaataa taccaataca accttctcca
       61 aagatgcgat gacatacgtt ctaacccacc gactattgat gttctgtacc acccttgcag
      121 aaccaaaaaa gccactacca aatatttggt agtggctttt tttgttttat ggatttttcg
      181 ctttttctgt tatggtgcta ttctttgatt tcagaaatag tatgtcgaac tttagcgata
      241 gaacgacgtg attctttttc gttgtaaaac atcaaaatca catatagaga gtccaaaatg
      301 cttagttgag aaatacggga agctaaagct tcagatcgga attctgtttc ttcagaaata
      361 gaaataaaaa cgacatcgcc aagtttagca agggaagaat tagcttggct agtaataacg
      421 attgtttttg ctccagtttt tcttacggtt tcagcaatat ggattgtttc ttttgattgc
      481 cctgtgtgag aaatcaaaac agcacagtct ttttccgtca ataaagaagc ttccatcaat
      541 tgaatatggt aatccgtgct gtgagaagtt gcgatagggg aacgcaaaaa tttatgataa
      601 gcgtcagttg ctacaatctc tgaaccgcca acaccgaaaa aatagacacg tttagattca
      661 ttgataatag tagccgcttt ttttagatcc ttttgttgta acaacttttt tgtgtcattt
      721 aaagttgaaa tactagactc gaacaccttt tgcgccatag tgagctcagt atctgttttc
      781 tgaatatttt cgtggataga aatagcagat agatcatttt cttggatcaa catggccatt
      841 ttaaaatctt taaatccatt ataaccaagt ttttttgtaa attgaaaaaa agtagagtca
      901 gcaatgccca gttcacttgc taaattgcta ataggactat gacttacttt gcttggattt
      961 tctaaaatat aatcggcgat agcctgttct tttgggctga agtcgttgta cattgttttg
     1021 atttgtagtc ttatggagac gctcatgaga attcctcatt ttcataataa gattatcatt
     1081 ttttccgttc tcattaatgt taaagataca aggagagtag gaaaaaatca aacaaaaaat
     1141 atttttgtaa aatctattta caaaaaaatt tttttgtata atgagggtat aagaaatgga
     1201 ggcgctatca tggaaattgg tgtaattggt ttgggaaaaa tgggattgaa tttagcttta
     1261 aacttaaaag agcaccatca caaagtacaa ggactcgaca tttcaagtac agctgttagt
     1321 caggcaagag aaaatgacat tcctgcttat caagagatct ctgaatttct agctactttt
     1381 gagcagaaaa aaatcatctg gttaatgctt cctgctggag agataaccga aaacatgtta
     1441 agaaaacttt ttccaaaact cggaccagga gacattatta ttgaaggcgg aaactcttat
     1501 tataaagatt caatccgtcg agcagaagag tttcagaaaa atgaaatcgg ttacttggat
     1561 tgtgggactt ctggaggaat cgaaggagca cgacatcaag cctgcttaat gattggagga
     1621 gataaagaaa cttttctatc cgtggaacaa ttattcaaag atgtagcaat tgaaagagga
     1681 tatctgtatg ctggtgcatc cggaagcgga cacttcttga aaatgatcca taatggaatc
     1741 gaatatggaa tgatgcaagc aatcggtgaa ggattccaac ttgtacaaaa aagtgagtat
     1801 gcttttgact tggaacaagt cgcacgtgtt tggaatcatg gttcggtgat tcgcggctgg
     1861 ctgatggaaa tcatggaaga tcagttaaac gaacatccca atttaagtaa ttatcgggga
     1921 atcgtttctg catcaggtga agcaaaatgg acggttgaaa cagcgctaga aatggctgtt
     1981 ccagttccag taattgcaac tagtttgttc atgaggaatc tttcacagga agaagatagt
     2041 ttttcagcaa aagtagtttc agcactaaga aatgggtttg gcggacatga aatagttgaa
     2101 aagggtgagt aaaatgccag attatcatat agcaatcgtt aattccagca gtttcggaag
     2161 agtctttcca caccacttgg aaagattaaa gtcagttgga gacgttcatt tctttactgt
     2221 tgatcaagag attccaggaa aagaactagc ggagttactt aaaggattca atatcattat
     2281 tgcaagtgtt acgccatttt ttcgacgaga tttttttgaa aacaaagatg aactgctatt
     2341 gatttcccga catggtattg gttacaacaa tattgattta aaagcagcaa aagaacacca
     2401 gacaatcgta tctatcatac ctgctttagt tgaacgaaat gctgtagcag aaaataatat
     2461 aactaatttg ttgtccatgc ttcgacgcac gacacaagca caagcaagag tcaaggacga
     2521 tcgatgggaa gatcgggcgg agttcgtcgg taggacgctg tttaacaaaa cagttggtgt
     2581 gattggtgca ggaaataccg gaagcggagt aatcgaaatt ttgcgtaacg gttttcgctg
     2641 tgatgttcta gcttatgatc cttacaaatc agatttatac atcgaaagct ttggtgcaaa
     2701 aaaagtagaa cttcaagaat tactggaaca atcagatatc atttgtttat gtgcgaattt
     2761 gacagaagag aactatcaca tgatttctga taaagaagtc gatcagatga aagaaaatgt
     2821 ttatctatct aatagtgcaa gaggcgctct agttgatgaa gaagcgatga ttaatggtct
     2881 gaaaagcgga aagatcgcag gatatgccac agatgtttta gaagaagaac cgggacgtca
     2941 agatcatccg tatttagcgt ttgaacaagt agtgattacg ccacatatat cggcctacac
     3001 aagggaatgt ttagaagcaa tgggtgaaaa atgtgtcaga gatgtcgaac agatcagtca
     3061 gcaccttctt cctgaacgtt ctgtccagac aaagagcaac tatataaaag gatgatgaag
     3121 aaaatggtga acggtttaaa agtgaaaaca ggccctcaat tttatttata tgaagaaggt
     3181 ggtatttcaa aagtttctga tctcttgaaa tcatacggcg cgaaaagagt actggtcacc
     3241 cacggaacgg tatcatggga aaaggcgcta cctaaattag tatttttgaa tgacgaaacg
     3301 attcaatttt tttatcatcg ttattctgga gaatgtagtt atgctgaagc cagacgaata
     3361 gctacaatca tcaaaaaaat gaaatcgatt tcgtagttgg cgttggcgga ggaaaactga
     3421 ccgatctagt gggttatagt gccaatcttg caagaatcga tttcggagtc atccctactt
     3481 tagctagtaa ttgtgctcca tggacacctc ttgctgtcat gtataaggag aatggacaag
     3541 cagaagggaa aacagaacac ttttacagac aagctgcttt ttttataaca gatccccaat
     3601 tagtgattga ttcccctgtt ccatatttca ttgccgggtt agcagataca ctagcaaaat
     3661 ggtatgaatc tgagctcatc ttagaacaag attttttgca agatgaatca tttttgaagc
     3721 tagcacaaga tactgcgaag atctgcaaag aagagatttt gaatcattct gctaaagcaa
     3781 tccaagatat ggcacaaaga aaactgacat cggagttcaa acagctttca gagattatct
     3841 ttgctgttgc tggtttagtt ggaggattag gagataaata cgcaagaaat gcggcagcac
     3901 atgctatgca tgacgctatc agtaaatata ttccggaaag ccatcgtttt ctacatggag
     3961 aaaaagtagc gtatgggatt ttctatcaac tggcactaga aggtcgctgg gaaaaaatag
     4021 acgagttata tcctttgtat cgggaattag aactgccggt ttctctagaa caaatgggat
     4081 tatttccgaa agataaacag ataatagata aaatggctga atttattgat tcgaaagaga
     4141 aagtgcattt gattcctata gaggtaacac agaaatcact gatacagtca atgatggaac
     4201 tggaaggtta tatcagaaag atctgaagga ggaggacaca tggaaatatt aagtgtagta
     4261 caaagtttgt tgattgcttt atgggtagcc gcggttatgt cccgctggtt aggtggagga
     4321 gccacgttga ccttacgttt ttctcctttg atgactggat tagtcgtcgg gttgatcatg
     4381 ggggaagttg cacaagcgat gattgttaca gccgctttgc aaatgattta tatgggggtt
     4441 ttttctccag gaggatcaat gccagctgaa ccatctattg cagcagctat cgcagtacca
     4501 gtcgcattat taggggatct gtcgccagaa gcagcgattg ccgttgcggt gccagtcgga
     4561 ttgctcggaa gttacttgta tcagtttcgt tttttcatca atactttttt aggtaaatat
     4621 acagacaaag ctgtagaaga tttgaataca aaagctatgg cccgatcaat tattctttat
     4681 ccaacggttg cctcattttt attattcgtt ccgcttgttt tcattgcttt atatttaggg
     4741 gcgccattga tcgctgatgt aatcaaagct ttagagggaa cagtcgttat ccacattctt
     4801 gaagtagtag gtggagggtt agcggcaatc ggtatcgcga caactgtata cgttatcggt
     4861 cgaaaagatt atctggtctt tttcttcctt gcttatttta tgagtgttgt tttgaaatct
     4921 ttagatatta cgatggttac ttatgccatt tttgggatta ttatcgcttt gatctttgtc
     4981 cagtcgcaaa aagggaaaca agtacagcct gccacaagca ataacaattc agcatctttt
     5041 gatgacgaag atgactatga tgacggattt taatttagga ggaatgggaa atggctgaaa
     5101 taatggataa tcaaacaggt gctcctgaag aaatcacgaa aaaagatgta acaaaagcct
     5161 atctgagatg gcattttgca aacgaaattc ctcactcttt tgaacgttac ttggcgccat
     5221 cactactata cggaatgatg ccaatcttga aaaaacttta taaagatgaa gactctttaa
     5281 aagcagcata taaacggcag ttactgttct tcaacactca attaagctgg ggtggcggtg
     5341 tgattactgg cctaatgtct tctatggaac agcaaagagc agaagaagag tatgaagaaa
     5401 aagagatctt gatgcaggat gacttgatgt ataacacgaa agcgggattg atgggggcac
     5461 tagcaggaat cggagatgca atcgattcag gaaccgtcca atatattttt atcgcaatcg
     5521 cggtaccttg ggcacaacag ggaagtcctt taggcgcact ttttcctttt atctgctttg
     5581 ggttgtatca ggttttacta ggggtatttt tcgcaagaca agctttcact atgggccgta
     5641 atgctacagg cctaatgcaa aacactggtg ttcagacagc gattgaaatg ctatcagttt
     5701 tagggttgtt tatgatgggg gtgcttgcgg gaaactatgt aaaagtagaa tcttcattga
     5761 aatttgcgat atccggacgt gagtttgtta tccaggaaat tcttgatcaa atcgtgccag
     5821 ggatattacc tttagctgtc gtaatgggtg tgtacttgtt ctatacgaaa aaaggattga
     5881 aagtcacaca agcattatta tggctgactg gaatattaat tgtgctagca ggaatcggta
     5941 ttttataaaa agaagggaac gtgaataaga tgggtgtagt caatttagcg cgtgtggatg
     6001 agcgtttgat ccatgggcaa gtaatggtaa cgttatctca aaaaagtgga gtgaattcca
     6061 tttttgttgt agacgaagtt gtagcaaaag ataaatttat gagagatctt tacaaaaatg
     6121 caggaagccg tacaggacaa aaaacaattg tcattacacc agagaaagct aaattctatt
     6181 gggatgaata tcaatttaaa gaatacaatt gtattttgat cgcaaaaaca gtccaaacga
     6241 tttacgactt agtaaaacac ggaatcccca tggaagaatt gaatattgga gggattgctc
     6301 aaaaaaatcc tgatacagat cttttagtga cgaaatctgt ttatttaaat aaatcagatg
     6361 ctgaaaaatt gaaagaaatg aatgaacaat atggcgtaaa gaatatttat tttcaagcca
     6421 ctccatctgc acctaaaaca ggattaaaag atgtattgaa caagtttgat ttgtcataaa
     6481 caaatgctta gaaaaaagat aaagagggcg aaaaaatgaa gaagaacgag ctgtttcgtg
     6541 attgggaatt tcgttatcgc tatatttacc gtaagcgccg tacaaaaaag agtaaacagc
     6601 gttttctttc agcattagta tcagatattt acagtatgag aacagatgtg acagtcattg
     6661 cttacgatac gctagcctac cgatcaaaaa atatttatgt tggagatatc gaaaaagcag
     6721 agaaagttat ctgtacttat tacgatacac ccgttcatgc attaggaagt tatttcatgt
     6781 ttgattggaa agaccaaagg aaaaaaacaa tctactctat attattgtcc ttcattttgt
     6841 tgttcagttt aggttggtgg ggaatgatga tatataacaa aaatcctcat cacgtattcg
     6901 atctgctatc cgtataaaca ggtatcactg tactagcatt tgggagctac tttttcttat
     6961 tgggaaaagc agctcgcgga tggcctagca gacaaacttt tattcgaaat acttcatcca
     7021 tattaacgat gctagaaatg atccgtacga ttgatgatcc gagtgtagcg tatgcgtttg
     7081 ttgatgaagg ctgttatgga gaaaagggct tagacagcgt gagatcgggt atgaaaaaag
     7141 aggctattct tttttatcta gactctgttg gggcagatac accgctacag ttttcgggaa
     7201 attatttttc aaataaagaa cagtggctga aacaagttga taagttgaaa gaaaaaaacg
     7261 tcaattatat ttttagtgca agaaaaaagc aagcgcagtt cttctatttg accaaaacag
     7321 atttacgagg gaaaacattt aattggcaaa atgccaatca gattattgct ctttttcgat
     7381 aagtaaaaag tgcaaaacaa ggagtgagaa gactaatgtt ggaaatcatg atcgttacac
     7441 atggtaagtt gagcgaagga ctgaaagatg cggcggaagt aattgtcggg acatcgagcc
     7501 atattgaaac aatgtgctta gagtctgggg aggacatcca aacattcgga gagaaggtca
     7561 aagaaaaatt aactatgatc aacacagcag aacccatgct agtatttgtt gatctaatta
     7621 gcgcaagtcc gtacaatcaa gcgctcttgg cagtcaatga actgactgaa gaaaagaaag
     7681 cagccactta tgtcataggg ggcgtgaatc tgccaatgtt gttagaagca atcaatcatc
     7741 agatgcttca cacaccgata gaagaagcgg tggaacaaat tgtcaaacaa ggaaaagata
     7801 atttaactgt ttggcatgct tcagcggaag aaaaaaaatt agatgaggac gatttttaga
     7861 aggaaggctg aaaagatgaa gtggggattt agatggtatg gtgaaaaagg ggattcgatc
     7921 ccattaaaat atgttcgcca aataccggga ataaatggga taattggaac tttgctgact
     7981 aaaatgcctg gagatgtttg ggagatttca gaaattgagg agttgaaagc atctgttgag
     8041 agccaaggac tggaactgct tggaattgaa agtgtagcga tccacgatgc aatcaaggca
     8101 gggacagatg aacgagatta ctatattgat aactatatac gaacaatcaa aaacttgtct
     8161 cgatgtgggg ttcgattgat ttgttatagc ttcaaaccaa tttttggatg ggcgaaaact
     8221 gatttgttta atgaaaacaa cgatggaagc tattctcttt tatacgatca gaaaatcgtc
     8281 gatcagatgg agccaggaga aatgtatcaa ttgatacaca gccagtcaaa gggattcaaa
     8341 ttgccgggtt gggaagaaga acggttgaaa aaattcgctc agctggaaaa actgtatgaa
     8401 ggaatgaccg aagaagaatt atttgaaaat ctgacttatt ttttagaaaa agtgattcca
     8461 gtgtgcgaaa aagcagatgt aaaaatggct atccatccag atgatccgcc atgggaactt
     8521 tttggttttc ctagagtgac gaaaaatctt ggcgacttga agaaaattct aaatgcagta
     8581 gattctccat ataatggact aacgctgtgc acaggatctt taggggcaaa tccggaaaac
     8641 gatttagttg aaatcatcca tgaggtaggt tcgcgcatcc attttgtcca cttcagaaac
     8701 gtggagtttt taggagaaag aaagttcaaa gaaacggcac atccctctac agaaggctcc
     8761 cttgatatgt atcatattat gaaagcgttg gtgcaagaag ggttcgacgg tcctatacgc
     8821 cctgatcatg gtagaaccgt gtggggtgaa gtggctatgc ctggatatgg cctgtatgat
     8881 cgtgcaatgg gactcactta catgcaaggt ctatatgagg cgataagtaa ggaaaaacca
     8941 ctgggagagc attatgaata aaatcaagct cttcatcttt gatatggatg gccttttatt
     9001 agaaactgga cgtttagctt atcgtgctta tgtaaaatca gcacaaaagt atgattatga
     9061 aatgcgtaag gaagtctatt atttactaac tggccaaaca gaaatggcga taagagaaca
     9121 aatgggcatt ttgtacggag aagatgttcc atatatcaaa tggcgagaag caatcaatca
     9181 atataaagaa aaaatcgtga aagaagataa gagagtatat acgaaaaaag gagcagaaga
     9241 aattttatct tttgcaaaag aaagaggaat ccatacaatc gtggcttcgt ctaatacacg
     9301 ggtaaaagta gaaatgtatt taaaaatgga aaatctatat gccttgtttg atcaaatcat
     9361 ttcaggggat gatgtaaaaa aaggaaagcc ggaaccagag atctttttga aagcttgttc
     9421 aaaaatgaat attcctccaa gtgaagcact tgtatttgaa gactcgattg cagggatcga
     9481 agcagcaagg cgagcgggca ttttgtcttt tctcatcaaa gatcatttga tagggttgcc
     9541 cgatcataat gggaagcata agttgaaagt agatgtaagt ttatatgaat ccaataaagc
     9601 agactatgaa ttttatgacc tgcatcaagc aaaacgattt ttagaaagta aagggttgta
     9661 tctctaataa agaggactat tttctagtcc tctttattta ttgtcctgca cgactgaggg
     9721 aacagatgaa aaagaagtaa ttttttattt tgaagtatct accttatttg tagtgaacaa
     9781 tttagaacaa acacaaaacg catctactgt tatctaccag tagatgcgtt taaagagaag
     9841 aacgagaatc gtccatatga gggtttccac tccttatgca gattttttta attcttgcac
     9901 tgcttgttcg atcgtaacac ctgtcgctac atgattggta ttttctttgt caaaaacgac
     9961 aaatagattc aaatctgtat ccaaggttac tcgatattgt atatctttgt tatagaatgt
    10021 catagccatt ctcctttctt taaatacttg ctgaaaggca acgaacgcgt tgataacgaa
    10081 attccattta taagtatacc accaattgaa aggttttcat agttaagaaa ttttaaagtc
    10141 aaaagttgca gataaaagca aataaacaag aaaacaaaaa gtgaatcaat cgcggttatt
    10201 caactttttc ttcgattcga agacaataga agacaatgaa ttttatattt cattgcatta
    10261 tccttgtgtt attagaaaaa gcatgatata ttaaatgagt aatctatttt gaaacgtaat
    10321 ttgagcgata tatctacata gataaaactc cttttgccta tcaaatattt attgcaacga
    10381 aaaaacgtac attgatacgt atcaggagga atttatttat gaataacggt acagtaaaat
    10441 ggttcaacgc agacaaaggt tttggcttta tcactggtga agatggaaat gatgtatttg
    10501 cacatttttc agctatccaa ggtgacggct tcaaaacttt agaagaaggc caagcagtgt
    10561 cttacgatgt tgaagatggt caacgtggcc ctcaagcaac aaacattgtt aaagcttaat
    10621 aaaaattgac ttttaaccgt cttttcgaaa gaaaagacgg tttttttgta cgaaaaaatt
    10681 cattggtcgt tgaatgggct gaatagtagt gtataaaaca attttgtgga gcgtgaagct
    10741 tttatggtag aggaaaatac gaataaagtg atgttgataa aaagattcct atcttgaata
    10801 tgaatcgaga tgtcttgaaa atgaatgagt ttgaccaatc attatcctat cgaaatttac
    10861 agtttcgttc gattggtctg tcaattaatg aaaaagtaaa aaagaatatg ttctaggaag
    10921 agggcggcac atctaaattt ttaagtaacg gacagttcaa atatcaagca ttgaaagagg
    10981 ctatcctact gtttgaagga atacgaatat ataaaaacga caaagaggaa aaagtagttc
    11041 attaaatccc ttcaagtgat gaaagaatga gatctaataa aacctgatct ttcatctgtt
    11101 tttttaataa cgtaataatt tttttatttt ttgtgctttc gccgttattg tagagtgatt
    11161 tagcat
//
LOCUS       DADVXM010000079        11000 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.084, whole genome shotgun sequence.
ACCESSION   DADVXM010000079 DADVXM010000000
VERSION     DADVXM010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.084"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            91..1536
                     /locus_tag="KB927_002207"
     CDS             91..1536
                     /locus_tag="KB927_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HBB6841108.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYSFEEKIP
                     HFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANANKHKFT
                     KEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVK
                     GEREKQFAYSAHTSCDDNGFILSTIITPGNIHDSQVAFQLVKQSKRLFPEINCVVADA
                     GYKTPKFVHFLTHLNLRPCLPYSRPKGKKGLLSKNEFLYDEYFDCYICPQDQMLAFST
                     VTREGYREYKSNPKECVNCPLLNQCTKSKNHQRVITRHVWGDLMDEVEHLRLTDLNKS
                     IYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKE
                     PLFFCSKIRNEVDKKLFQARVTSLEQLLSTV"
     gene            1543..1902
                     /locus_tag="KB927_002208"
                     /pseudo
     CDS             1543..1902
                     /locus_tag="KB927_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            2174..3220
                     /gene="gmd"
                     /locus_tag="KB927_002209"
     CDS             2174..3220
                     /gene="gmd"
                     /locus_tag="KB927_002209"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HBB6841109.1"
                     /translation="MKKALITGITGQDGSYLADFLLEKGYEVHGITRRASISNTARID
                     HLMGKITLHDGDLSDSSSLIRIISIVQPDEIYNLAAQSHVQVSFDVPEYSGDVDALGV
                     MRILEACRILGLTKKTKIYQASTSELYGKVEEVPQRETTPFHPYSPYAVAKQYGFWIT
                     KEYREAYGMFAVNGILFNHESERRGENFVTRKITLAAGRIAEGLQDHLELGNMDSLRD
                     WGYAKDYVECMWMILQHETPEDFVIATGEQHTVRDFTEKAFAANGMTIRWEGTGIDEK
                     GYDVETGKMLVCVNPQWFRPTDVDNLWGDPTKAKTVLGWNPQKTSYEELVNIMAKHDR
                     ELAKREAAMKNAVK"
     gene            3300..4313
                     /locus_tag="KB927_002210"
     CDS             3300..4313
                     /locus_tag="KB927_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841110.1"
                     /translation="MATLCRCEAKITLVCGANHLDFAKRNLEQELPKELIDRVRYRPI
                     NTDIGLINREGTLLVDTGKLTEICEYFLAKVPSLAKTEAEWLKREAVSAVLCDMPIWA
                     MDACDMAGVPFLYVGNFTWTELYREFLPEHIWKEYAKRYGKIQHTMLYALNNEEMLEF
                     LQNSEKTPTSVVARPIHNDEVQRIKSQHEKPPVFVALGMSARFKQPIDVSHAPYDFIT
                     TLGVPLVGENVTVISNSTPNTQDYIAAADYVITKAGWGTVAECILAQRPMALFARDTV
                     LEDRTTICKLQKLGLAISVTPENLHRVERVIEDLKQLDTSNFDTFYDAASEIADKLIS
                     LMQ"
     gene            4350..5294
                     /locus_tag="KB927_002211"
     CDS             4350..5294
                     /locus_tag="KB927_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014424865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HBB6841111.1"
                     /translation="MMEKDAKIYVAGHRGMAGSAIVRELNRQDYNNIITRTHKELDLC
                     RQDAVEAFFAQEKPDYVFLAAAKVGGIIANQNALADFMYENMILEMNVINSAWENGCK
                     KLQFLGSSCIYPRMAPQPMPESCLLTSELEKTNEAYALAKISGLKYCEFLNKQYGTDY
                     ISVMPTNLYGPNDNYHPTHSHVLPALIRRFHEAKEAGLPTVTCWGDGSPLREFLYVDD
                     LANLCVFLMNNYSGDETVNAGTGKELSIKELTEMVAKVIGYEGEILWDTSKPNGTPRK
                     LLDVSKATKLGWTYKTELEDGIRLSYEDFLNNPMRAER"
     gene            5362..6675
                     /locus_tag="KB927_002212"
     CDS             5362..6675
                     /locus_tag="KB927_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBB6841112.1"
                     /translation="MNIVLLSGGSGKRLWPLSNDIRSKQFIKIFKTEDGYESMVQRVY
                     RQIKKVDNDATVTIATSKTQVSAIHNQLGEDVGVSVEPCRRDTFPAIALATAYLVDVM
                     GIDPEESVVVCPVDPYVEDDYFEALKSLSDQADKGEANLVLMGIEPTYPSEKYGYIIP
                     ESAEQTAFVNTFKEKPSEAVAKEYIAQGALWNGGVFVYKLKYVMERAHQLIDFVDYQD
                     LFNKYDTLTKISFDYAVVEHEDKIQVQRFAGMWKDLGTWNTLTEGMEESIIGKGVMNE
                     NCDGVHILNELDVPVLAMGLHDVVICASREGILVSDKEQSSYIKPFVDKFEQQIMFAE
                     KSWGSYKVMDVEAESMTIKVTLNASHSMNYHSHKNRDEVWVVLAGTGKTIVDGYEQVV
                     KAGDVITMSAGCRHTIMADTELKLIEVQLGKDINVKDKQKFELEY"
     gene            6759..7661
                     /locus_tag="KB927_002213"
     CDS             6759..7661
                     /locus_tag="KB927_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HBB6841113.1"
                     /translation="MMNLQKELRCLLLRKLGMLYAPGWTELCCVWSEYQGMTLTEVLQ
                     EHPEFLGTHPQTKGELPILIKFIDAKKDLSVQVHPTDEYAIEKENGQLGKTEMWYVLD
                     ASLIYGLQKITEEAVIREAIAQGTVERYLQKVPVKKNDVFFIEAGTIHAIGAGALIAE
                     IQENSNLTYRLYDYDRVDKNGKKRELHVDKALEVANLKGLSEPKQPLRVLKYRAGVAA
                     ELLCRCKHFEVSRMIVNTERRQTVHYRADSISFRVLLCVNGCGTVRFDNESLDIYKGD
                     CLFVPADSTEISIHGSIQFLDVRG"
     gene            7666..9318
                     /locus_tag="KB927_002214"
     CDS             7666..9318
                     /locus_tag="KB927_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBB6841114.1"
                     /translation="MNYKVEYERWLNHANADIIEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLADYLNKNYEAASVVVGYDSRIKSDVFAKTAADIF
                     AANGIQVHLWPELLPVPTVSFATRYLKADAGVMITASHNPSKYNGYKVYGADGCQITT
                     EAATAILAEIEKLDIFADVKMDGDASKIASIQSEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEIKEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKSAHGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PADPVMVKTIVTMDLGERIASNYGVRTIDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLLDKLNEIYTKYGYCLNTLHSF
                     EFDGAAGFTKMQEIMVEFHKGLDIIGGKKVIETLDYSKGLNGLPKSDVLKFMLEDNCS
                     VVVRPSGTEPKLKTYISVSAENKEAAEAMEAIMAAELAEMFE"
     gene            9342..10208
                     /locus_tag="KB927_002215"
     CDS             9342..10208
                     /locus_tag="KB927_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841115.1"
                     /translation="MEELFSNALKSVKSNRVLYTASFFARSSLLYLQEIGQLTALKAH
                     TSRRTGLSSYLCFLVEVGSGTLEYKGQKYTLQVGDMVFIDCLKPYVHESSEDDLWTLR
                     WCHFNGIGMTEVYKKYLERGGQPVFKTSKTDKYADLLRSLHMVAEGQEYVRDMKINVL
                     LSELLMHLMEDSWNPDKVPNFSTKKMELQNIKQYLDDHYTEKITLDQLSAEFFINKQY
                     LAKIFRETYGTTVVGYLNQKRITQAKHLLRFTNLSMEEIATKIGITDANYFSRTFFKV
                     EGVRPSEFRKMW"
     gene            complement(10250..10441)
                     /locus_tag="KB927_002216"
     CDS             complement(10250..10441)
                     /locus_tag="KB927_002216"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841116.1"
                     /translation="MIIRDDHIYTCDSCHYSFPADEQPERCPDCEKTATRLDTEIETE
                     DYYRVRAEIKAEIKALNAG"
     gene            10471..>11000
                     /locus_tag="KB927_002217"
     CDS             10471..>11000
                     /locus_tag="KB927_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841117.1"
                     /translation="MQLLLYRIGDSTKIRFLINVRFRVIYSTVLPKGIPQRQKWMIHM
                     EEIMQMILGNAKFQLGQVVSTPAVLETFNPLQTANGIPEALSNLWFRQEISIAEIEDA
                     VLDAKNGKELANSLNRIKLFRKFTLDRELDGMVRLKGTDVWKNISYLKVYTATPPKKP
                     TPPRFQSNGWSLFFSH"
BASE COUNT         3084 a         2247 c         2695 g         2974 t
ORIGIN      
        1 agactgtaga caaagtccat tttatggatg atgtctacag tcttttcttt tataatagat
       61 ttatgaaaac gaatgcaagg agtgatagct atgatgtcta aaaacaatac gaatggtaga
      121 aatcaatttg cgatgcttac gattgatgat ctagttcctc aagatcatct cgttcgaaag
      181 attgatgccg cgcttgattt tgaatttatt tatccaatcg tcgaagccac ttactccgat
      241 ttaggtcgcc caagtatcga tccagtgatt ctgatcaaat tggtgtttat tcagtattta
      301 ttcggtatcc gttccatgcg acaaaccatt aaggaagtcg ataccaatgt cgcttaccgc
      361 tggtttttag gctactcctt cgaggagaaa atcccccatt tctcaacttt tggaaagaat
      421 tatgttcgcc gatttagaga aacgacggtg tttgaggata tttttgccta tattttagaa
      481 caagcagtta aagcaggttt tgtaacagag gataatttgt atctggattc tacccacatc
      541 aaagctaacg ccaataaaca taagtttacg aaagaaatga cccatgatga agcgaaagcc
      601 tatcaggatg aattagaaga tgagatcaat cgtcaacgaa tagaggctgg aaaacgccct
      661 tttactttgg acttagaaaa ggaagtgaag ctgaaagaaa gaaaaataag taaagctgat
      721 ccggaaagcg gctactacgt caaaggcgaa cgagaaaaac aatttgctta ttctgcccat
      781 acttcatgcg acgacaatgg atttattctt agcacaatca tcactcctgg aaatattcat
      841 gacagtcaag tcgcctttca gctcgtcaaa caatcgaaga gactttttcc tgaaatcaat
      901 tgtgttgtcg ctgatgctgg gtataagaca cctaagtttg ttcacttttt gactcatttg
      961 aaccttcgac cttgtttgcc ttattcaagg cccaaaggga aaaaggggct attatcaaaa
     1021 aatgagtttc tctatgacga gtattttgat tgttatattt gtccgcaaga tcaaatgctc
     1081 gctttttcaa cggttactcg agaagggtac cgagaataca aatccaatcc aaaagaatgt
     1141 gtgaactgtc ctctgctaaa ccaatgtacc aaaagtaaaa atcatcaacg agtcatcacg
     1201 agacatgttt ggggagatct gatggatgaa gtggaacatc ttcgcctaac agatctgaat
     1261 aaatcaattt acaaaaaacg gaaacaaacg attgaacgaa tatttgcgga tgcaaaagaa
     1321 aagcatggga tgcgttggac caagtatcga ggcttggaaa aagtcgcgac gcatacgatg
     1381 ctagtgtttg ctgcaatgaa tttaaagaaa ttagccacct ggctatggaa aggcaaggag
     1441 cctttatttt tttgttcaaa aattcgaaac gaagtagata aaaagctgtt ccaagctcga
     1501 gttacgagtt tggaacagct tttgtctaca gtctgacaac ctctgacaga ggttgagatt
     1561 tttcatactg atcgtggaaa agagtttgat aaccaagcta ttgatgaatt atcaacaact
     1621 tttgacatca atcgatcatt gagtcataaa ggctgtcctt ttgataatgc cgtagctgaa
     1681 tcaacttata agtcgttgaa agtagaattt gtctatcaat acacatttga aaccttacaa
     1741 caattggatt tggagttatt tgactatgtc aattggtgga accgccttcg gttgcacggt
     1801 acacttggct acgagacacc ggttggttac cgtaaccaga gattggcgca gcgaatcctt
     1861 gataatgagc tcggatgtgc taacgctagc gaggcagtct aactttaact gttagctcct
     1921 gccgaagatc gtcacatccg aggaggctca ttgtcaagga caatcggaat agcatacgga
     1981 aagaagttct gcaccttata aaatttgtca aaaaaactgt tgccattcca attcacgaaa
     2041 aactaatatt gtgctaatgc gtgcgtagat tgttctatga aatatcgaaa attatcgtgt
     2101 attcttgaaa agtattagaa attacgagcc atttatatgg ccttatcact tacataggaa
     2161 aggataatgt atcatgaaaa aagcgctgat tactggtatt actggtcagg acggttccta
     2221 tctggcagat ttcctgctag agaagggcta cgaagttcac ggtatcactc gccgtgcttc
     2281 tatttccaat accgctcgca ttgaccattt gatgggcaag atcacccttc atgacggtga
     2341 cctgtccgac tcatcttctc tgattcgtat catcagcatt gttcagcctg atgaaatcta
     2401 taacctcgct gcacagagcc atgttcaggt ttcttttgat gttcctgagt actccggcga
     2461 tgttgatgct ttgggcgtta tgcgtattct ggaagcttgc cgtattctgg gcctgacgaa
     2521 gaagactaag atttatcagg catctacttc tgagctgtat ggcaaggttg aagaagttcc
     2581 tcagcgtgaa accactccgt ttcatcctta cagcccttat gctgttgcaa agcagtatgg
     2641 cttctggatc actaaggaat atcgtgaagc ttatggcatg ttcgctgtca acggtattct
     2701 gttcaaccat gaatccgaac gtcgcggtga gaatttcgtc acccgtaaga tcaccctcgc
     2761 tgccggccgc attgcagaag gcctgcagga ccatctggaa ctgggcaaca tggactccct
     2821 gcgtgactgg ggctatgcaa aggactatgt tgagtgcatg tggatgattc tccagcatga
     2881 gactcccgag gacttcgtga tcgctaccgg cgagcagcac actgttcgtg acttcaccga
     2941 gaaggcattc gcagcaaatg gcatgaccat tcgttgggaa ggcactggca ttgatgaaaa
     3001 gggctacgat gttgaaaccg gcaagatgct cgtttgtgta aatccacagt ggttccgtcc
     3061 gactgacgtt gacaacctgt ggggcgaccc gactaaggca aagaccgttc tcggttggaa
     3121 tccgcagaag acctcttacg aggaactggt taacatcatg gcaaagcatg accgtgaatt
     3181 ggcaaagcgc gaagctgcaa tgaagaacgc agtcaagtaa gctgacattg aataaacata
     3241 tctgtttcta tctttccagt cacggcttcg gacatatcgc gcggaatctg cccattatta
     3301 tggcaacact ctgccgatgc gaagcgaaga ttacactggt ttgcggcgca aatcatctgg
     3361 attttgcaaa gcgcaatttg gagcaggaac tgcccaaaga gctgatagac cgcgtgcgct
     3421 atcgtccaat aaacacagat atcggtctga ttaaccgtga gggcacccta ctggtggaca
     3481 cgggtaagct gaccgagatc tgtgaatatt ttttggcaaa ggttccttct ttggcaaaga
     3541 cagaagccga atggctcaag cgagaagctg tcagcgcagt gctttgcgat atgccaatct
     3601 gggcaatgga tgcctgcgat atggcaggag tacctttcct gtatgtagga aacttcactt
     3661 ggacagagct gtatcgcgaa tttttacccg aacatatttg gaaagaatat gccaagcgtt
     3721 acggtaaaat tcagcacacc atgctttatg cgctaaataa cgaagaaatg ttggaatttc
     3781 tccaaaacag cgaaaaaaca ccgacttccg ttgtggcgcg tccgattcat aacgacgaag
     3841 tgcaacgcat taaatcacag catgaaaaac cgcctgtatt tgtcgcactc ggtatgtccg
     3901 cgcggttcaa acagccgatt gatgtcagtc acgcgccgta tgatttcatt acaacgctag
     3961 gtgttccgct tgtgggagaa aacgtaaccg ttatttctaa cagcaccccc aatacacagg
     4021 actatatagc ggcggcagat tacgttatta caaaggctgg atggggaact gttgcggagt
     4081 gtattctcgc acagcgtccg atggcactgt tcgcccgcga tacagttttg gaagatagaa
     4141 caactatttg taaattgcaa aaactgggtc tggcaatttc cgtcacaccg gaaaacctcc
     4201 accgcgtaga gcgggtgatt gaggacctca aacagctaga cacctcaaat tttgatacat
     4261 tttatgatgc tgcgagcgaa atcgcagaca aattgatttc tctcatgcaa tgagagatgc
     4321 tctaaattta gaaaggagca agcattatta tgatggaaaa agacgcaaaa atctacgtag
     4381 ccggtcatcg tggcatggct ggttccgcaa tcgtgcgcga gctgaaccgt caggactaca
     4441 acaatattat cacccgcacc cataaggagc ttgacctgtg ccgtcaggac gctgttgaag
     4501 catttttcgc acaggaaaag ccggattatg tatttctcgc tgctgcaaag gttggcggta
     4561 ttatcgcaaa ccagaacgct ctggcagact tcatgtatga aaacatgatt ctggaaatga
     4621 acgtcatcaa ctccgcatgg gagaatggct gtaagaagtt acagttcctc ggttcttcct
     4681 gtatctatcc gcgtatggca ccgcagccga tgccggaaag ctgtctgctg acaagtgagc
     4741 tggaaaagac caacgaggct tatgcactgg caaagatttc tggcctgaag tactgtgagt
     4801 ttctaaacaa gcagtacggt actgactata tctctgttat gcctactaac ctgtatggac
     4861 ctaacgacaa ctatcatcct actcacagtc atgtgctccc cgctttgatt cgtcgcttcc
     4921 atgaggctaa ggaagcaggt ctgcctactg ttacctgctg gggtgatggt tctcctctgc
     4981 gcgaattcct atatgttgac gatctggcaa acctgtgtgt gttcctgatg aataactata
     5041 gcggtgacga gactgttaat gcaggtactg gcaaggaact gtctatcaag gaactgaccg
     5101 agatggtagc aaaggttatt ggttacgaag gcgagattct gtgggatacc agcaagccga
     5161 acggtacacc tcgtaagctg ctggatgttt ccaaggcaac caagctggga tggacatata
     5221 agactgagtt ggaagatggc atccgtctgt cctacgagga cttcctgaat aacccgatgc
     5281 gtgctgaacg ctaatttacc gaggttgctg tgatttttga ggattgcagc agcctctttc
     5341 ttataaaaag gagagatcat tatgaatatt gttttactgt ctggcggttc tggtaagcgc
     5401 ctttggccgc tgtctaatga catccgttcc aagcagttca ttaagatttt caaaactgaa
     5461 gatggatatg aatccatggt tcagcgtgtc taccgccaga ttaagaaggt agataacgac
     5521 gcaactgtta cgattgcaac ctctaagaca caggtttctg ctatccataa ccaacttggt
     5581 gaggatgtgg gtgtatctgt agagccttgt cgccgcgata ccttcccggc aatcgcattg
     5641 gctaccgctt atctggtaga tgtgatgggc attgatccag aagagtccgt agttgtttgc
     5701 ccggttgacc cttacgtaga agatgactat tttgaggccc tgaaatctct gtccgatcag
     5761 gctgacaaag gcgaagctaa tctggtgctc atgggtattg aaccgactta tccttccgag
     5821 aagtacggct acatcattcc tgagagcgca gagcagactg ctttcgtaaa taccttcaag
     5881 gaaaaacctt ctgaggctgt ggcaaaggaa tatatcgcac agggtgcact gtggaacggt
     5941 ggtgtgtttg tctacaagct gaagtatgtc atggagcgtg cacatcagct gattgacttt
     6001 gtagattatc aggatctgtt caacaaatac gatactctga ctaagatttc cttcgactat
     6061 gccgttgttg agcatgagga caagattcag gtacagcgtt ttgctggtat gtggaaggat
     6121 ctggggactt ggaatactct gaccgaaggt atggaggaat ccattatcgg taaaggtgtt
     6181 atgaatgaga attgcgatgg cgtacacatc ctgaacgaac tggatgttcc tgtgttggct
     6241 atgggtctgc atgatgtggt catctgtgca tctcgggaag gtattctggt ttccgataag
     6301 gaacagtcca gctatattaa gcctttcgtt gacaagttcg agcagcagat catgttcgca
     6361 gagaagtctt ggggtagtta taaggttatg gatgtagaag cagagagcat gaccattaag
     6421 gttactctga atgctagtca ctccatgaat tatcacagcc acaagaaccg tgacgaggtg
     6481 tgggtggttc tggccggtac tggtaagacc atcgtggatg gatatgagca ggttgttaag
     6541 gctggcgatg tgatcaccat gagtgctggc tgtcggcata ccattatggc agatactgag
     6601 ctgaagctga ttgaagtaca gcttggcaag gatatcaatg ttaaagataa acagaaattt
     6661 gagttagagt attaaaaaac ggaggagggc tcgttataca gaaaccgttt ttattgaagc
     6721 cttccgcaaa ggattatctg tgggggggaa ccgcctgaat gatgaatttg caaaaggaat
     6781 tgagatgtct cctcttgcgg aaacttggaa tgctctacgc acccggatgg accgagcttt
     6841 gttgtgtctg gtcagagtat caggggatga ccttgacgga ggtgttgcaa gaacacccag
     6901 agtttctggg aacgcatccg cagaccaaag gagaattgcc gatcctgatc aaattcattg
     6961 atgcgaaaaa ggatttgtct gttcaggtac atcccacaga tgaatatgca attgaaaaag
     7021 aaaacgggca gcttggaaag acagagatgt ggtatgtact ggatgccagc ttaatctatg
     7081 ggctgcagaa aataacagaa gaagctgtga tccgtgaagc gattgctcag ggaactgttg
     7141 agcgttatct tcagaaggtt ccggtcaaaa agaatgatgt gttctttatt gaggcgggaa
     7201 cgattcatgc gattggtgcg ggtgcactaa ttgcagaaat tcaggaaaat tccaatctga
     7261 cttatcgtct ctacgattat gaccgtgttg acaaaaatgg taaaaagaga gaacttcatg
     7321 tagacaaagc gctggaagta gcgaacttga aagggttgtc agaaccgaaa cagccgcttc
     7381 gtgttctaaa atatcgtgct ggtgtagctg cggaattgct ttgcagatgc aagcatttcg
     7441 aggtctctcg tatgattgtc aacactgaga gaagacagac ggtacactat cgtgcggatt
     7501 caatcagctt ccgtgtgttg ctgtgtgtca atggctgtgg taccgttcga tttgataatg
     7561 aatcgttgga catctataag ggggactgcc tttttgtgcc ggccgattct actgaaatca
     7621 gcattcacgg gtcgattcag tttctggatg tgagaggata ataatatgaa ttataaagta
     7681 gaatatgagc gttggctgaa tcatgccaat gcagatatta tagaagaact gcgttcctat
     7741 tctgagaagg acattgagga ctctttctat aaaaatttgt ctttcggtac tggtggtctg
     7801 cgtggtacca tcggtgcagg cactaatcgc atgaacgtac acaccgtagg taaggcaagc
     7861 caaggtctgg cagactatct gaataagaac tatgaagccg cttccgtggt ggttggctat
     7921 gattcccgta tcaaatctga tgtgtttgca aagactgccg cagacatctt tgctgcaaat
     7981 ggtattcagg tgcacttgtg gccagaactg cttcctgttc ctacagtatc ttttgcgact
     8041 cgttatctga aggcagatgc cggtgttatg attacggcat ctcataaccc ttctaaatat
     8101 aacggctaca aggtatacgg tgcagacggc tgtcagatta ctaccgaggc tgctactgca
     8161 attctggcag aaatcgaaaa gctggacatc tttgctgatg taaagatgga tggcgatgct
     8221 tctaagattg catccattca gtcggaagtt ctgactgctt tcatcgaaga agtgaagggg
     8281 cagtccgtcc tgtttggcga agaagtggac aagaatgttg ctatcgtgta ttctcctctg
     8341 aatggtaccg gtctggtgcc tgttacccgc accctggcag agatgggata cagcaatgtg
     8401 accgttgtgg aagaacagcg tctgccggac ggtaatttcc caacttgtcc ttatccgaac
     8461 cctgaaatta aggaagctat gtctctgggt atggagtatg ccaagaagta caatgcggat
     8521 ctgctgttgg ccactgaccc tgactgcgac cgtgttggta tcgcagttaa gagcgcacat
     8581 ggtgactatg ttctgttgtc tggtaatgag actggtctgc tacttctgga ctacatctgt
     8641 tctcagagaa ttaagcatgg aaaaatgcct gctgaccctg tgatggtcaa gaccatcgtc
     8701 accatggatt tgggtgaacg tatcgcatcc aactatggtg ttcgtaccat cgatgtgctg
     8761 accggcttta agtttatcgg tgagcagatt ggtatgttgg aaaaggctgg taaggttgac
     8821 agctatatct tcggctttga ggaatcttac ggctatctgt ccggtagcta tgtccgtgac
     8881 aaggacggtg ttaacgctgc ttatctaatc tgtgaaatgt tctcttacta caagactcag
     8941 ggtatcagcc tgctggataa gctgaacgag atttatacaa agtatggcta ttgtttgaac
     9001 accctgcatt ccttcgagtt tgacggtgcg gcaggtttta ccaagatgca ggaaattatg
     9061 gttgaattcc acaagggtct cgatataatt ggtggtaaga aggttattga aactttagac
     9121 tacagtaagg gcctgaatgg tctgccgaag tctgatgttt tgaagtttat gctggaagat
     9181 aactgctctg ttgtggttcg tccttctggt actgagccga agctgaagac ctatatcagc
     9241 gtcagcgcag agaacaagga agccgccgaa gctatggaag ctattatggc tgctgaactg
     9301 gcggaaatgt tcgagtaaga aaagaaagga gaaatcttgt aatggaggaa ctgttttcta
     9361 acgctttgaa atcggtgaag tcaaatcgtg tgctgtacac ggcatcgttc tttgcaagat
     9421 cctctctttt gtatttgcag gaaattggac agctgactgc tctgaaggca catacatcta
     9481 ggcgtacagg attgtcatct tacctttgtt tcctggtaga agttggttca ggcacattgg
     9541 agtataaggg gcagaaatat acgcttcaag taggagatat ggtgtttatt gactgtttga
     9601 agccgtatgt ccatgagtca tcagaagatg atttgtggac tttgcggtgg tgccatttta
     9661 atggcattgg tatgacggaa gtctacaaaa aataccttga acgaggtggt caaccggtct
     9721 ttaaaacatc aaaaacagat aagtatgctg acttgctgag gagccttcat atggtggcag
     9781 agggacagga gtatgtccgg gatatgaaaa tcaatgttct actcagtgaa ctgctgatgc
     9841 atttgatgga agattcttgg aatcctgaca aagtgccgaa tttctctaca aaaaaaatgg
     9901 aattgcagaa cataaaacaa tatctggatg accattacac ggagaagatt acgctggatc
     9961 agttgagtgc agagtttttt atcaataaac agtacttagc taagattttt cgtgaaactt
    10021 acggtacaac tgttgtcggt tatctgaatc agaaacgaat cacacaggcc aagcacttgc
    10081 tacgctttac aaatctaagt atggaagaga ttgcaacaaa aattggcata acagatgcaa
    10141 actatttttc cagaactttt ttcaaggtgg aaggtgttcg tcccagcgaa ttccgcaaga
    10201 tgtggtaata aaaagccggc ggtgttgagc cgccggtcag tacctgtcgt taacccgcat
    10261 tcaaagcttt aatctcagct ttgatttcag cacgaacacg atagtaatct tcagtttcga
    10321 tttcggtatc cagccgagtt gctgtctttt cgcagtcagg acaacgctct ggctgttcgt
    10381 cggcagggaa gctgtagtgg caggaatcac aggtgtaaat gtgatcgtca cgtataatca
    10441 tcacctacca atccagtgct tagatttttc atgcaattac tattatatcg aattggtgat
    10501 tccacaaaaa tccgcttctt gataaatgta cgattcagag tgatatatag tactgtactg
    10561 ccaaagggaa taccacaacg gcagaaatgg atgattcaca tggaagaaat tatgcagatg
    10621 attttaggga acgcaaaatt ccagctcgga caggtggttt cgacccctgc tgtattggaa
    10681 actttcaacc ccctgcagac cgcaaacggc attcccgaag ccttgagcaa cctttggttt
    10741 agacaggaaa ttagtattgc ggagatcgag gacgcagttc tggatgccaa gaacggcaag
    10801 gagctagcaa acagcctcaa ccgcatcaag cttttccgca agttcaccct cgaccgagag
    10861 ctggacggca tggtcagact gaagggcacg gacgtctgga agaacatcag ctacctcaag
    10921 gtctacaccg ccacgccgcc taagaaaccg acccccccaa ggttccagtc gaacggctgg
    10981 agccttttct tctctcataa
//
LOCUS       DADVXM010000080        10966 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.085, whole genome shotgun sequence.
ACCESSION   DADVXM010000080 DADVXM010000000
VERSION     DADVXM010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10966
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.085"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            718..2595
                     /gene="ltrA"
                     /locus_tag="KB927_002218"
     CDS             718..2595
                     /gene="ltrA"
                     /locus_tag="KB927_002218"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBB6841118.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            2726..3103
                     /locus_tag="KB927_002219"
                     /pseudo
     CDS             2726..3103
                     /locus_tag="KB927_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            3103..4308
                     /locus_tag="KB927_002220"
     CDS             3103..4308
                     /locus_tag="KB927_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBB6841119.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKNSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFTDDGTWIDP
                     LPFLNSSKK"
     gene            4324..4968
                     /locus_tag="KB927_002221"
     CDS             4324..4968
                     /locus_tag="KB927_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841120.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTFKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNLVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            4979..5785
                     /locus_tag="KB927_002222"
     CDS             4979..5785
                     /locus_tag="KB927_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841121.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEISTNAFVNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFAVKLSHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQIESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKENI"
     gene            5808..6038
                     /locus_tag="KB927_002223"
     CDS             5808..6038
                     /locus_tag="KB927_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841122.1"
                     /translation="MKRANLVGKDTFAEQKVLIKAYLKVVKAKEICQEVNLSNTTISE
                     LKNGRKSLDTLKFRSFEALYLAAKKYFTAERK"
     gene            6302..7174
                     /locus_tag="KB927_002224"
     CDS             6302..7174
                     /locus_tag="KB927_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841123.1"
                     /translation="MKSTDWIKHTWLPLKRNSKRKEFWILQLWPLGKLCSYLARFILD
                     LIIYSIVVFGTAYYLLNDPNRIAASDIFTVLMTLIFVMLLSIFTQIVMQFTRQKLTAG
                     KLFKSLFDLIIVNAILATLIKQIEQFGRTTKGVKEFLMTFVHFVNGHMYLFEVGIILF
                     LVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYYVDFGRYDELINTDIVHTSIHEATVKG
                     IRTTLKDGQETKAIDRRKEVYNFYEVEANLRYGIGKLSLNGRNIPQNKPYIGWKSDAL
                     EVTKKLPMEEEEIQ"
     gene            7937..8212
                     /locus_tag="KB927_002225"
     CDS             7937..8212
                     /locus_tag="KB927_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841124.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            8254..8676
                     /locus_tag="KB927_002226"
     CDS             8254..8676
                     /locus_tag="KB927_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841125.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKSINESVHARVDPFDPTKFLKR"
     gene            8696..10288
                     /locus_tag="KB927_002227"
     CDS             8696..10288
                     /locus_tag="KB927_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841126.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDQEFSETSNEAQSLMGNGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYVVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNSLTKVVKEPVRYD
                     RHAMNLLNEVYRNLPEKRSEWNYGDENRTKLSPYTREKLDELTQYVLTKEPEYQEYIQ
                     ISKALKEEAKNLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            10300..10635
                     /locus_tag="KB927_002228"
                     /pseudo
     CDS             10300..10635
                     /locus_tag="KB927_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10782..>10966
                     /locus_tag="KB927_002229"
     CDS             10782..>10966
                     /locus_tag="KB927_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841127.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT         4145 a         1665 c         2253 g         2903 t
ORIGIN      
        1 gtgaaaagct gtgggttgca agtagtctaa aaactattgt aataactctt ataacgagaa
       61 gtcaaatgag tgggtaacgc cacaaagggc ttccactgat actccgacat gcaacaagta
      121 gtttatgcag accaacgttg tgtgaagctc ggtgaagtcg gctgaaggat accgtaaggt
      181 aaaagaaata gtgaatacca cgaaagttct ttagaggtaa agggtgtatc cgataagtcg
      241 ggtgtccaaa aaaacttaat atggtgagta tgtacaaacg tactgacgaa ctagcgaatg
      301 tactgtccga aaggcatagc tcctagaaat gggagagaca gtgagcaaaa aatcactcat
      361 tgtgctaact tgtggttgag taaaagtcgt tgttatgaaa gaccatgctg cgttacaggc
      421 gtaggagaag ttagggggca aaagctagca tctaagttaa ggcatgtgga tagatataag
      481 ggaacagggg aagccatcaa catggagagt gcatactcga tgaagtggta gtaagaaata
      541 tgtgaatgac aaataactta ctttagtgat ggtgaaagta gagtcacgac tgatgaaggt
      601 tctgtaatgg aactggagga acaggctcga ttcgtctgta aaagtcatga aacccgttca
      661 accatgggat tctcgtatga ctaaaaaggt cacgagccaa ttggagcgtg ataaaccatg
      721 acaaaagaaa caagtccaaa agataggaag ttgcggcatg cagaatatta tggcatgacg
      781 gaaatcttcg ataagatata ctccaaaagt ttgaagggag ataatttcaa gaatctaatg
      841 cagattatca tttctgataa caacattgtc ctagcatatc gtaatatcaa gagaaatcac
      901 ggtagtgtga caagaggaga agatggagta acgattaaag atattgaaaa tctcaaccgt
      961 aatgaattcg tagaaattgt taggaagcga ttcgcacatt ataaccctcg gaaagtaagg
     1021 cgtgtagaaa ttcctaaata taatggtaaa ttaagaccgt tgggtattcc atcaatatgg
     1081 gatagaatcg cgcagcaatg catcttacaa gtattagaac caatatgtga agcaaaattc
     1141 aataatcaca gctatggttt ccgcccaaat agatcagcag aacacgcaat agcagattgt
     1201 atggcccgaa tgaatcaaag tcacatggaa tatgtggtag atgtagatat caaaggtttc
     1261 ttcgacgaag tcaatcatac taaactcatg agacaaatct ggtctatggg tatacgagac
     1321 aaacagcttc tcttaatcat taggaaaatg ttaagagcac ccgtagtact tccaaatggg
     1381 aagttgatat acccaacaaa aggaacacca caaggcggaa tacttagccc attacttgcg
     1441 aacatcaatc tcaacgaatt tgactggtgg atagcaaatc agtgggagga aaaagatgcc
     1501 aaagagctaa aacatcattt taggaaaaat ggagcttggg ataaaggtaa tatctatcac
     1561 aagctcagaa agagtacaac tctaaaagaa atatacctag tgagatacgc agatgatttt
     1621 aaaattttct gtagaaatta taatgaagcg aaaaaagttt tctatgcaac taaaatgtgg
     1681 ttacaggagc gtctaaagtt accaatatct gaagaaaagt caaaaatcac aaatctttca
     1741 aaagaagaaa gtgaattttt aggctttacg atgaaattag tgaccaaagg taacaaaaag
     1801 gttgttaata cgcatatagg tacaaaagca caaagcatga ttaaagtgaa actaaaaaaa
     1861 caaatcaaac gaattcaaaa aagtcctaat agcaaagata cctttatcta tattggagtc
     1921 tataacagta tggttattgg gattcataat tacttcaaaa ttgcgactca ttgtagtgta
     1981 gcaatgcgaa aaattgcaag agaactcaga ccaagttttg aaatacgact acgagaacaa
     2041 ggaatctcaa aagaaggaca atacggaaag tacgaaggat acaagcctta cctacggtca
     2101 ggacaaatac gatatataag agggtttcca atattaccag tagggtatat tcaacacaga
     2161 catccgatgt gtaaaaaaag aaatattaat aaatacaccg aagaaggtag ggaagccatt
     2221 cataagaagc aacaaaccgt agaagaatgg aagatatcgt ggttgtgtag caatccagtg
     2281 cttagtaaga gagcaacgat tgaatttgcg gacaatcgaa tttcaaaatt catcgctcaa
     2341 aagggaagat gtgcagtaac aggtgaggag cttatcttat ctgaaatgca ttgtcatcat
     2401 attatccctt atcatgaaag caaaagtgat agctatgaaa acctagtgat tgttactgag
     2461 gaggttcatc gggtaataca cgctacacaa agtgaaacga ttgaggaact tctaaaatat
     2521 ctaaaattaa atccaaaaca aaaagaaaaa ctcaatgagt tgagattaaa agttggtaac
     2581 gaagaaatat cttaataaat atttgtagga cgggaaaaca gaatgtcttt tatagacgag
     2641 ggaacgccgt atgcggtgaa agtcgcacgt acggtgtgga ctgggggaaa agacggagat
     2701 aatatcaaac tcttacctat cagtatcgat taatccagat tttattgaaa cggtaaatta
     2761 tgtcacaaac tttcaacgag aaatgcgtaa agtagaagca atgactgttt tagctacaca
     2821 atccccacaa gaaatggtgc cagaaaatat gtcttctgat aacttctcga aactgaagaa
     2881 agtctttgaa ttttcttcta cgaagatctt tatgcgtatg gatgaatcta ttttacgtca
     2941 tatagaagga ttagttggta aatcaatgac aaactcagaa ttagaatcca ttcctcaaca
     3001 aaatcaagga gacgctgtga tcaattttgg ctcaaaagaa accattcgtg ttcattttag
     3061 tccgaacaaa cgtcaattaa aattgtttga tggaggaaaa taatggaaaa ccaaaatgaa
     3121 agtttaatca agcagtatgt taagcgtcgt gcaaagcgac gcttattttt gtggttgttt
     3181 ggtacttctg caggtttgat tactattttg attactgtgt tcgtgaccct ttttctaata
     3241 cttgcggcgg gttcgattga taattctgat tcagattcaa gtagtggtgg cgaagctttt
     3301 acaggagaat attcggaagg cttaccgatt tataaagaaa tcaaaggaag aggccctttt
     3361 tctgatgaga ttgcgcaata tgctgtaggt gcagcagtga aatataaatt attaccaagt
     3421 gtgatccttt cgcaatacgg ttatgaatca gcgtttggta cgtcggcgtc cgcaagaaat
     3481 gatctcaact attttgggat tacttggttt gatggttgtc tgtttcctaa aggaactgca
     3541 cgaggaattg gtggcattga aggtggctgg tacatgaagt ttcccaactc aaaagctgcc
     3601 ttctcatatt acggctttat ggtagccaca caatccaatt ttaatgcatg tgtaggaaat
     3661 aaaagccctg gcgcaagttt attgatctta ggacgaggcg gttatgccgc tgcaggaatt
     3721 acggaagata gtccgtatta tacaggatgt atgtccatta tcacttctaa taaattaacc
     3781 gaatatgatg aattcgccat caaacattgg ggtgaaggtg gcaataacaa cggcacgatc
     3841 actggtgaat ggacgaatcc attccctggc agcagtttag ataaaaattc cttcagtggt
     3901 ggtcaattat ttggaacaaa tccaggcggt gaattccgtc cgaatggctt ccatgatgga
     3961 ttagactttg gttcagtcga tcatccagga agtgaaattc acgcggtgca tggaggaaaa
     4021 gtcgtgtacg ttggcaatcc tggtatttca ggtttaggtg catgtgtgat cgtgattaat
     4081 tacgacggtt tgaatatggt atatcaagaa tttgcgaata gtacaggaaa ttctcgtgtg
     4141 aaggttggcg atcaagtgaa agttggtcaa gtaatcggga tacgagatac agcacacttg
     4201 catttaggtt tcactcgaat ggattggcgt caagcacaag gacacgcatt cacagacgat
     4261 ggtacatgga ttgatccatt accatttttg aatagcagca aaaaatagat caggagaaaa
     4321 aatatggaaa ataaaacttt aaaaatcgtc ttaacagctg caattagcgt tagtttaatc
     4381 ggcaatatcg cgttgttttg gcagctgaaa gaagaacaag agacaaatac ctttaaaatt
     4441 gaagaagtgg ctaaaaacgc gtctgagaag ctcaaaaaaa attcctctga ggcacaggcg
     4501 aagatcgaca agttaaatca aaccatcaat gagaaaaacc aagaaatcga tcagctgaag
     4561 caacaagatg gcacaaaagc aaaagaggaa gtaactgaag cacaaagaaa gacggcagaa
     4621 gagttcggtc aattggccat tgataaatca ttaagcagaa atgaattaac ggaaaaacta
     4681 aaagatgtcg caacccaaga agtgatcgac aaattaagtc ctgcagacga tgatcaccaa
     4741 catgatgatt acggaagtta ctcctttaca ttaggtgacg tgcaaactta cgctcaaaca
     4801 agcagtgtaa aagaggaaca aaatcttgtc gtatttgttg attatacaat cggcaatcct
     4861 caattcaaag atgtcaaacc gcaaaaaata aaaggtggat taactgtcac tgaaaaacaa
     4921 gtagatggtc aatggaaagt cacagacttt agttatttca ctcgttagga ggaagaaaat
     4981 gagtaagaaa aaaggagcaa gacaacgttt caaaaaacga aaaagttatc ttagatggct
     5041 ggggatcttt atgattctcg gctttttgat tcttgctagt ccaatttata cgcataagaa
     5101 ggtagacata ccagatgaga taagcacgaa cgcatttgta aacacgaagg aactgacgat
     5161 ggtttcaaaa gaaaaaggag cgaaccagca attagttttt gaatttgcaa tcgacgatga
     5221 agatcaaagc ttattaaaag aactggctaa tcttaattat cgcgtagaag taaagacagc
     5281 taaaggggat tatcaagcaa taaaagccaa agtgatcaaa gtgtctgatg attattttgc
     5341 agtgaagcta tctcatgtac cagaagaata tattgccatg cgtttaacca ttattcctga
     5401 aaaaattgat ccaaaagtgg atatgcaaga accgcaagat ctgatttatt acgttcacga
     5461 agataaggtt aaagatcaag tgaaagatga agattatgaa caacatgcga tcaattacaa
     5521 agtgaaagga tacaaaaaag aacaaaaagc agcacaaaaa cagattgaat ccttccaagc
     5581 aaccattgat ttgaatgaag aattagtgaa gaaactaaaa gatcaattgc cttatcaagt
     5641 tgcagacgat caggaaaata ctgaaaataa gattaatagt taccagcaag aaattgaaac
     5701 atcgaaaacg caaatgaaag atcaagaaga gatcattcaa aaacttcaag aaaaaattga
     5761 tcgtatgaca aaagaaaata tttagaagaa taggtggagt aaaagaaatg aagcgagcga
     5821 acttggtcgg caaagatact ttcgctgagc agaaagtatt gattaaagcc tatctcaaag
     5881 ttgtaaaagc taaagaaata tgtcaagaag tgaatttatc taacacaaca atatctgagt
     5941 tgaagaatgg tagaaagagt ttagatacct taaaattcag atcatttgaa gctttgtatt
     6001 tagctgctaa aaaatatttt acggctgaaa gaaaataaaa acaggaggat tttatgtgaa
     6061 aaaagtgtat caaaaatgtt tatggatcag ctatatcacc gtaggtatcg ttggcttctt
     6121 ttttattgta gccgtgacct tgggaacgat ttttctatgg tttactaatg aagatttatt
     6181 attgaaggga ctcatgagtg taatctcatg cgtcctattg attttgttgg ggacagaaat
     6241 caacaaactt ctgccttctc gttggcaaga aaagaagaaa gaaatgagag aagaaattga
     6301 aataaaatcg accgactgga tcaaacacac ttggcttcct ttgaaaagaa atagcaaacg
     6361 taaagaattt tggattctac aattatggcc attaggtaaa ctttgtagct atttggctcg
     6421 ttttatactt gatttaatca tttactcgat tgtagtattt ggaacggctt attacttatt
     6481 aaatgatccc aataggattg cagcatcaga catttttaca gtgctaatga cgttgatttt
     6541 tgtcatgcta ttgtctattt ttactcaaat agtcatgcaa tttaccaggc aaaaattaac
     6601 agcaggaaaa cttttcaaaa gtctattcga tttaattatt gtaaatgcaa ttctagcaac
     6661 tttaataaaa caaatcgaac aatttggaag aacaacaaaa ggagtgaagg aatttttaat
     6721 gacgtttgtt cactttgtaa atgggcacat gtatttgttt gaagtgggta ttattctctt
     6781 tttagtcggg tatgtatcca cgaaacttat taaacgttca attgaaaaag aaattgagat
     6841 tgacttgatt ccgacacttc ttggttatga gtactatgtt gattttggaa gatatgacga
     6901 attgatcaat acagatattg ttcacacgag tatccatgaa gctaccgtta agggcatcag
     6961 aactacgtta aaagatggcc aggagacgaa agcaatcgac cgaagaaaag aggtctacaa
     7021 tttttatgaa gtcgaagcaa atctaagata tggcattgga aaattgtcgt taaatggaag
     7081 aaatattcca caaaacaaac catacattgg ctggaaaagt gatgctttag aagtaactaa
     7141 aaagcttcct atggaagaag aggagattca atgagtctag tcaatttgaa tcatttgttt
     7201 gaagatatca gtaatcattt ccaacagttc tcaataagag tttatattat tcattagttt
     7261 attttgattg aaaaaagaag aaaaaatgta gaaagttgtc tgtgaaaaaa gtgtatgcta
     7321 tactgataat gcaaacacat aaaacattta atactcaaaa agagccctag cagttgcagc
     7381 tgcgtaaggc tcttttcttt attcactatt aaccaaataa tgaacaggct agctgtcttt
     7441 atcatgttta gaatctaacc atttgttaat gagatgggag aaaacattaa ccacgattct
     7501 aacgcaaaca tcaagcacat aaaacattta acactcctcc tttctggctg aagatttcaa
     7561 ccaaacagga agacagcgta tcaattatag catacacttt ttcttaaatt catttttcat
     7621 atgacaaaat atttccttct aatcgacaaa gttagaagga ttttttattg tctaaataca
     7681 caaataacct taatttttaa agagcataag gaaacgtgat atcactttct tacgaaaggt
     7741 gctaggtagg ctgtgcctac cacgtttcta agaaagataa atgatatcaa aattttggat
     7801 ttgtgtgtag atttgtgggt aggatgaaag cgaatgtggg cagtaaaata agcgtttgtg
     7861 tgtagcaaaa tcaaaaaatg tgtagggata tgtgtagcta cacatatccc tacacataat
     7921 aaatttggag gaaaatatgg acttattaat tagaaatatt gaagaaaagt acattaataa
     7981 aattgacaaa cgttgtgaag aacttacggt caagactggc aaaaaatgga gtcgaaatca
     8041 atacctaaaa gttttgatcg aaaatgattt tgatcacgct cttctgaatt ataaaaaaga
     8101 ccaatttgat cggttgttag aaaaatttgt ggatattcaa acttataata caaaaacttt
     8161 agaagaatat attgcaacaa ataatcaatt aattggtttg ttaattgaat aataaaaata
     8221 gtattgtgaa tttataaaag gaggaaatca attttggcaa aagcaacaag aaaacatgta
     8281 tatctttacg atatgcatat cgaagtactt gatgaaataa tttctactca tgaagatata
     8341 tctaattata gtgaagcagt cagacatttg tgtatgatgt atgatccaaa aatcgaagaa
     8401 aaaataaatc caattcaaat taaattgaat gcaatgggaa aagaaatttc tattttaacc
     8461 gagatggttt cagagtttgc ggatcttcat ttgaaagata cagggatttt aattggtaca
     8521 aattcaactg tttaccaaga agcaaaagag cgtgtggaag ggaaaataaa agcgaatcaa
     8581 acgaagaagt attctcctaa aatcaagaaa tcaataaatg aatctgttca tgccagagta
     8641 gacccgtttg atccaacaaa gtttttaaaa agataaaaag tagaagggga acatgatgaa
     8701 taaatcgcct gcagtcattc tcacttgtca atttaccttg cccaataaaa aatctttttc
     8761 aacatacatt gattatatga caagagaaaa agcgctggaa gaaatggaac gacgtacgcc
     8821 tgaagaagaa caggaactgc aacgaatcaa gaatgcttta gaggattttt atattcctga
     8881 aggagaaact ttttcggaga gtaagacgga tcaagaattc agcgaaacgt cgaatgaagc
     8941 tcaatctttg atgggaaatg gaatcaactt tgacaagtta gaggaacaag attttaccaa
     9001 atatctttct tatatgaccc gtcactatgc gttagaacaa aagaaagaac tgacgcaaag
     9061 ggaacaaaaa gaataccaac gcttgaacca agcaataaaa aaatatcaaa cagagccaca
     9121 caaaaaagct tcaggaaacc ttcctggagt tttttctatg gcttcagacg aagtgaaagg
     9181 aagtgatctg aaggagatta agcaaatctt ccaaagagga caacaaaaag gctcaatcat
     9241 ttatcaagat gttgtctctc atgataattc gtatcttgaa aaaataggat tgtacgatcc
     9301 caaaacagat actttagatg aagaagggtt aaaagcagct ggaagaaaaa tgatggagac
     9361 attattcgag aaagagcaac tgaacgaaac aggctactgg atggcaacga ttcaccgtaa
     9421 cactaaacat atccatattc attttgcagt tgttgaaaaa gaaaatacgc gtaaacctta
     9481 cactgaggtt gaaaatggtg tgagttatgt tgtaccgaaa ggaaagagaa ggcaagcaac
     9541 attagacgca atgaaaacca attatgtgca tgagttagaa cgtttctctt atgaaaagga
     9601 tcgaatgatt ggtatggaga aacgaaattt attgacacga aaaagtgatt tgcgtaacag
     9661 cttaacaaaa gtggtaaaag agccagtacg ttatgatcga cacgcaatga acttattaaa
     9721 tgaagtatat agaaacttac ctgaaaaacg ttcggaatgg aattatgggg atgaaaatcg
     9781 aaccaaactt tcaccataca caagagagaa actcgacgag ttaacccaat atgtgttaac
     9841 aaaagaacct gaataccaag aatatataca gatttcaaaa gcattgaaag aagaagcaaa
     9901 aaatctttat ggggaaagca agagagaatc aaaggatgca gagaaaaatg ctctctttga
     9961 tttaaaaaag cgcacaggaa atgccatcct aacagagctg aagagacagg atagtcaaat
    10021 aaaaccatta atagaaagtg ttgatcagat gcaatctatt tacaatgaac gatcctttcg
    10081 aacgcttaaa caattgccaa cgaatgaata caaatatagt tacgaagaat tcatgaagcg
    10141 caggaaacaa ttccaacaaa gagttgtcac gcagcggagt ttgcgtcaat taaatcgaac
    10201 gattaatgcc catgaagaaa aataccacgc aagtaaagca tacgaagagc aacaacgaag
    10261 aattcaaatg gaacaagaaa gacagtagga ggaagagaaa tgaaacgata tttgaatcaa
    10321 tggaaagtca tagaaggatc actaaaaaaa gaacgaatcg aacaacttcc cgattgtttg
    10381 gaaaaagagc atttgtttca gataagagaa atgttgagaa gcgaacagat tgatccaaat
    10441 taatttttag tcgttgagta cccagctact ggtgtgtatt gttgtaatca tgtgaacggt
    10501 gaaaaatatt ttatcattca agaatatgag gccaagttaa caccttatta tactacttgg
    10561 gaaatgaatg aagagggaat caataacttt ccatgtaaaa gcataaaaga gtctatttca
    10621 ctcacagagt gttagttatt aagtgaataa aagaagtaaa agagtcctga acgtgattgt
    10681 ccaggactct tttttttcac tgaattgttt tccgccaatt cattgagtgg tgcgatttcc
    10741 gactacatta tatcaaaaga aagagaaggg aggaagcaga aatggcttat tcaactattg
    10801 gagttgttgt tgaaaaaagc agagacaatc tcgtttttgt gacagaaatt caaacaggca
    10861 gagcttttgt agtcacagac aaagctgcaa aagcttatca aagtggcgat attttaacgt
    10921 taaatctgac tacgaagacg ttcgtcgatg cggcagaaga ttatcc
//
LOCUS       DADVXM010000081        10662 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.086, whole genome shotgun sequence.
ACCESSION   DADVXM010000081 DADVXM010000000
VERSION     DADVXM010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.086"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            34..657
                     /locus_tag="KB927_002230"
     CDS             34..657
                     /locus_tag="KB927_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841128.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1107..2156
                     /locus_tag="KB927_002231"
     CDS             1107..2156
                     /locus_tag="KB927_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6841129.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2153..3034
                     /locus_tag="KB927_002232"
     CDS             2153..3034
                     /locus_tag="KB927_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6841130.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3037..3807
                     /locus_tag="KB927_002233"
     CDS             3037..3807
                     /locus_tag="KB927_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6841131.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4086..4940
                     /gene="aroE"
                     /locus_tag="KB927_002234"
     CDS             4086..4940
                     /gene="aroE"
                     /locus_tag="KB927_002234"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBB6841132.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5118..6281
                     /locus_tag="KB927_002235"
     CDS             5118..6281
                     /locus_tag="KB927_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6841133.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6398..6808
                     /locus_tag="KB927_002236"
     CDS             6398..6808
                     /locus_tag="KB927_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6841134.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6982..9210
                     /gene="topB"
                     /locus_tag="KB927_002237"
     CDS             6982..9210
                     /gene="topB"
                     /locus_tag="KB927_002237"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6841135.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9381..9665
                     /locus_tag="KB927_002238"
     CDS             9381..9665
                     /locus_tag="KB927_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841136.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9825..10061
                     /locus_tag="KB927_002239"
     CDS             9825..10061
                     /locus_tag="KB927_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6841137.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10058..10456
                     /locus_tag="KB927_002240"
     CDS             10058..10456
                     /locus_tag="KB927_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBB6841138.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3725 a         1773 c         2253 g         2911 t
ORIGIN      
        1 taataaaaaa taggagaaaa agtagaaaag aaggtgtttg ttatttggga agtagttaaa
       61 tcgagagtac aagaaatgaa tgaacatttc tcagtgtcat tcgcagaaaa tccaagtaag
      121 tattttcgac gtcttgtttt tctgctcatc ttatcattgc tgttaacagt tgcaatgttt
      181 ttattgccgg aaaaaatccg agaagagcaa gtaaatagtc tcgtttattc gtccatacca
      241 accagcaaat tgaaaccttt tgattacagc aaagctgatc agaaaatcaa acaaagccgg
      301 gcgatatcgg tgatgttcag caaaccgaac gggaaaacct atcaggacat gcttgatgtt
      361 tttaatgatc ctgagcttat ggaagaattg aatcgaccga tcttttatta tccgatcgtt
      421 tatgatgtac atgaactgga acaaaaatat aacatacgaa cggatgaagt gacatttatt
      481 ttctttgatg gaggaaaaga agcaaatcgg ataactgcgg gtaagggagg aataactgat
      541 tttgataagg agttgatccc tgaactgaat cgacttccgt tagccaatat caaacaatta
      601 gaagaagaat tggatagaac gggagtaact tcccaaaatt ccgagattgc taattgagac
      661 attggcgcga tgaaacggtg ggtctatata gcgctatttt taattatcag aacaagtgat
      721 gtttgatctt caaaataaca aataaaaaat taaaaaatat agttgacgaa attcaaaaat
      781 tcgattagac ttaaatcaat tcttaaggaa agggtgacct gtaatgaact tatcaaaacg
      841 tatttcagca gaaaacaaaa aaaattggcg cagctggcgt agataagttg tattaatggt
      901 gagactttcc catagataca actttttaga gtgcatttct aaagcttgta tctatgctag
      961 acatgaacat tgactgccgc atagattaga atctatgcgg ttttttgtgt aaagacaatg
     1021 accgctttgg ccattgtctt tttttgtaga ctggatactt gcctgattat aataaataaa
     1081 aagattgact ttgcaggagg aaaaaaatga aaaacaaacg attaataaca gttgtagtaa
     1141 ttattttagt ttatttagca ggtgcattta tttatggaaa agcctcaggc gaaaaagaaa
     1201 gtacttcgac gaaccagaca aaaaaaacaa cagttgttgg ggtattgcaa tacgtgagcc
     1261 atccggcatt agatgagatt tatcgaggaa tcaaagatgg tctgaaagaa gaaggattaa
     1321 aagaaggaga aaatcttgag atcaaatttc aaaatggaca agccgatcag agcaagctag
     1381 ccacaatgag tcaacagcta gtacaatctg atccagatgc cttgattgga atcgcaacac
     1441 ctgccgctca atcattagca aacacgactt catcgatccc agttgtgtta ggtgctgtaa
     1501 cggatcctgt gggggctgga ttagtcgctt ctttagagaa acctggtggt aatgtaacag
     1561 gtgtttctga tcagccgcct gttacttcac aaatcaagct tgcttctgat ttgttgccaa
     1621 atgcaaaaaa agtcggaatc ttgtatgctt cttcagagga taattcaaaa taccaagtag
     1681 cacaagcaga agaagctgca aaaaaagaag ggttagaatc agtaaaatat gcggtgcctt
     1741 ccactaatga gattgcacaa acggttcaag tgatgagccg acaagtcgat tttatctatg
     1801 ttccattaga taataccatt gccaatgcga tgcaaacagt ggtaaaagaa gcaaacaaag
     1861 caaatatccc cgtcattcca tctgtggata caatggtgga acaaggtgga ctagcaacaa
     1921 tcgggatcaa tcaatatcaa ttagggcttc aaagcggtaa gatggcggca gaacttgcga
     1981 gtggaaaaga aaaaccggaa acgacgcctg tttatacatt tgatcaaggg gatacagtga
     2041 tcaatcaatc tcaagctgat cgcttaggaa tcattgttcc ccaatcgatg aaggaaaaag
     2101 ccaaaatcat tacagatgac tcgcagcaag aaacatctaa ggaggatgac aaatgatcgt
     2161 atcagctatt tcacaaggca tgctttgggc aatattagga ttagggattt tcatgactta
     2221 tcggatctta gactttcctg atatgacgac agaagggtcc ttcccattag gtgctgctgt
     2281 ctgtgtgaca gctattactc atggggtagc gccgattgta gctacattat taggcgtagg
     2341 tgctggcatg atagcaggac tcgttacggg gttactttat acaaaaggaa agataccggt
     2401 tattttagca gggattttag tgatgtcagg attgaactca gttattttgt ttgtgatgcg
     2461 aacaccaaat ctttctttat tgaatcatcc gattctacaa gacagcttcc atcgctttgg
     2521 gttacctgat tactttgaca cagtccttct tggcttcatc tctttgggca tcttgattgc
     2581 tgtactgcta ttcttcttca atacagattt gggtcaaggc tatattgcga caggagacaa
     2641 cgaaacgatg gctcggtcgt tagggataaa aaccgatcgt atgaaaattt taggtttaac
     2701 tttgtcgaac ggtgtcattg cattatccgg tgcgctgatt gcccagaacg acggatatgc
     2761 agatgtaaat aaagggattg gcgtaatcgt catcggtctt gcttccatca tcatcggtga
     2821 agtgatcttc caagaattga cgctagcaga aagattgatt gctattgttg tcggcagtat
     2881 catttatcag ctattgattt tagtagtaat caaactaggg tttgacacga cttatctgaa
     2941 gttgttctcc gctatcatct tagctatttg tctgatgatc ccgcaattga agaaagcact
     3001 gaacttaaaa acgggttttg agaaggaggc atagtaatga ctgatatatt gacaatcaaa
     3061 aatggcagaa aagtcgtaaa caatggaatg aatgaagaga aagtactatt ggatgaaatt
     3121 aaccttacaa tcagagaagg ggacttcatc actgtccttg gcgggaatgg tgctggaaaa
     3181 agcacactgt tcaatacgat cgctggtacg cttcaactca gtcaaggatc gatctctttt
     3241 aaagatcagc tgatcacaaa agattcagaa gaaaaaagag cacgattcct ttctcgagtt
     3301 ttccaagacc ccaagatggg aacggctcct cggatgacag tagcagaaaa tttgctactt
     3361 gcacaaaaaa gaggtcaaaa acggaaattc cgtttacgta acttgaaaaa tcaaaaagaa
     3421 gattttttca gactatgtca agaagtcggt aatggcctag agcaacactt ggatactcca
     3481 gcgggtgaat tatctggtgg tcaacgccaa gcattaagct tgctgatggc gacgatcaca
     3541 gctcctgagt tactattatt agatgaacat actgcagctt tagatcctaa aacagctaaa
     3601 gcattaatgc gattaacaaa tcagcggatc aatgaacaaa aattgacttg tctcatgatc
     3661 acgcatcgaa tggaagacgc cttgaaatac ggaaatcgtc tgatcgtact ccaaaaaggg
     3721 aaaatcgttc aagatatttc tgaaaaagaa aagcaacatt tgacaatggg cgaccttttg
     3781 cagttctttg aagaagtagt ggattgattt cgacagaaaa attcctttca gtagaaggac
     3841 ttgaaaactc attgacatct tcctttgatt catcctatac ttaaaacaat aaacaattaa
     3901 acatatttgg gtgttttgta ggatcacgta gtcaatgatt ttaacaatta aatagaatat
     3961 tctttgctct gacaagtaaa cgatgagaaa agaatttgct actttgccac ctagacgttt
     4021 cgtacttttt cgtatcaaac gctaagtggc tttttttatt gaagtaagaa caaaggagga
     4081 ataagatgat ttctggacaa accaaattag ctgggctctt tgctgatccg gcttctcaca
     4141 gtttatcccc attgatgcac aatactgctt ttgaagcaaa caacatcgat gcggtgtatt
     4201 tagctttcca agtaaatcca atgaatttga agcaagcagt cgaaagtatt cgaacttttg
     4261 atatgttagg tgtaaatctt tcgatgccga ataaaacagc ggttattcct tatctggatg
     4321 aggtaagcca ggaagcgcaa ttgatcggag cagtgaatac gatcgtgcac gaaaagggtc
     4381 gtttgattgg ctataatacc gatggtgcgg gcttcatgca atccgtgcaa gaagctggga
     4441 tttcgatcaa aaagaaaaaa atgactctac tgggagctgg aggtgcagca aaggcagtca
     4501 ctgttcaagc tgcgttagac ggcgctgagg aaatcgtagt ttataaacga aacaaccaaa
     4561 cattcgctca agtaaaagaa acattcgaac aactcagcta tcgaacttct tgtaagataa
     4621 aagttcgtga ctttgccgat acgcatcaat taagaaaaga cttgaaagaa agctgtcttc
     4681 tagtcaatgc aacagatatc gggatgggaa agaaaatcaa tcagtcaccg ctcttagata
     4741 taagcatgat gcatgagaat ctagcggttt ttgatttgat ttatgcacct agagaaacac
     4801 gtttattaaa agaagcaaaa aaagtaggag caaaaggata caatggactt ggcatgttga
     4861 tctaccaagg agcaatcgcg tttgaattat ggacaaagga aaagatgccg atccatgtga
     4921 ttgaaaagct gtttgattaa aaaaggataa tagataaaga tcttttattc tcgcataaac
     4981 ggtctcaaga aaagtaatcc tttatgtatc gaagcattta tttcgttatt ttttattaaa
     5041 ttatcaaaaa atgataggct tttgtcgatt ggttatcgta tcctttattt atcagtaaga
     5101 aacgaggagg aaccacaatg agtcggatgg atcgctataa ggacatccat aagaaggcga
     5161 aacctctgaa gcgggatacg gggagtattt ttgctagaag agaacgaaaa cgaacgcgta
     5221 tggaaaatga ggaagatgct acccgtattt atgaaagaga gcagcattca tttgaacatt
     5281 tgaaccaata cgagcaacag atatacagag atgcaccaag agcagaagaa caacaaaaaa
     5341 ataaaaaatt tttcaatcgg caaaagaaga acaaaccgtt aaaacctcga agaaagcgat
     5401 cgtggaaaaa aatcattcta tcgattttgc ttgttttgat cctttattca ggtatctcat
     5461 tttttattgg taaatatgta gctgaacatg acacaagctt agaggcagcg acttcagaaa
     5521 cctttcatgg gcaaaaagcg acgaatggtg cgcataatat tttgatcctt ggaagtgata
     5581 cacgcggaga agatgccggg cgagccgata cgatcatggt cttacagttg gatggtcctt
     5641 cccataagcc gaaactgatt tcttttatgc gtgacagctt cgttacgatc ccaggggtag
     5701 gacaaaataa gatcaattca gcttatgcat acggaggagc cgatctagtg cgtcaaactt
     5761 tagtagaaaa ttttggaatc gattgtcaat actatgcgaa agtcgatttc aaatcgtttg
     5821 aaaaagtgat cgatgcctta ttcatgaacg gagtgaagat cgatgcagaa aaagatctga
     5881 atctggatgg tgtagatatt aaaaaagggg tccagaagat ggatggacat gttcttttgc
     5941 agtacgcacg tttccgaatg gatgaacaag gagactttgg ccgtgtcaga cgccaacagc
     6001 aagtaatgaa cgctattttc agccaattga agaatccatt gaatctgatc cgtgcacctt
     6061 atgcagctgg taaagcttta ggatatacat ccacagatgt cactgcttgg ttcttgacga
     6121 aaaacctctt ttcgattgca cgaggagctg gtggcattga tcgaataagt gtgccagtag
     6181 acggttcgtg gaattatggg caaagtgatt atgctggcag tattcttgaa attgataatc
     6241 aaatgaatca atctgctatt acagattttt tgaataaatg atcataaaaa agatcaagaa
     6301 gaagctgcgc aaggcttttg tcatgaatca atcaaacgat tcactcgtaa aaaacgcttt
     6361 cttatggtag atttaaccaa gagaggagct gtttacattg gatatctatc tgaacttcaa
     6421 aaatgagtcg cgtgaagcca tcgcttttta tgaaaaagtt tttcagactg aagcatcagg
     6481 tatcaccaca tacggtgaaa tgcctggaat agaacaaatg aacttgccag aagaagcaaa
     6541 aaatctaatc acgaatgcac ggctgaacat ttatgataca ttagttatgt ttgcagatac
     6601 gccagaagga attggtcctg aattagttgt gggaaataat gtttctttag tcatccagac
     6661 aagaaatgaa gaagaaacga agcgcctatt tgaaagctta gctgagggtg gtaagattga
     6721 gatgccactg gatgctgttc cgtgggctca gttgtatggg atggtaactg atcgatttgg
     6781 catcaactgg cagattaacc aagagtgaca gctaaagatg aatattttct ggaaacatca
     6841 agcagcaaac ggatcatcgt ttgtttgctt gatgtttttg tgtctatttc gactatacgg
     6901 tatctttttt ttattgccag atgcgaaaat atgttccata atagagaagt ccgcaaaaaa
     6961 ttaagtaacg gaggtcagaa gatgaagacg gtgatactag ctgaaaaacc ttcacaagca
     7021 aaagcctatg ccgaaacctt ccaacagcaa aagcggcatg aagggtatta tgaaatcagc
     7081 gatccattgt ttgctggtga agtaaccatc acttatggtt ttggacattt ggtagatatg
     7141 gttgctccag gagcttatga agagcgttgg gcaaaatggt ctttagaaaa tttgcctatt
     7201 ttcccagaaa ccttccgtta cgaagttcca atggacaaac gtgcacaatt ttcgatcgta
     7261 aaacgagaat tgcagtcagc cgataccatc attattgcaa cagatggtga tcgagaaggt
     7321 gaagccatcg cgtggtcgat tattcgacaa gcaaacgcat tttctaagga aaagaactat
     7381 ttacgtttat ggatcaattc tcttgaaaaa gaagcaatct atgaaggttt taagaatctc
     7441 caacctggaa agaactattt tccaaaatat aaagaagcgc aagcaaggca gaacgctgat
     7501 tggctgattg gaatgaatgg aagtccatta tatagcttgc tacttcaacg aaaagggatt
     7561 gatggcagtt tttctcttgg tcgtgtacaa acaccgacac tctatatgat ttatcagctg
     7621 caagaagaaa tcaaacactt caaaaaagaa acgtactttg aaggagaagg tttaattacg
     7681 acaaacaaag ggcagttttc tggaaaaatc gtaccaaaaa aagcatttaa aacccaagaa
     7741 gagttaacga aggaaataga aaaacttgga gcgcatttag gtaagcaaaa cggacggatt
     7801 cttgaagtta cgaaaaagga aaagaggttg catagtccac gtttattttc gctatctagt
     7861 ttgcagacaa agatgaatca gctaatgaaa gcaagtgcca aagctacact tgatgctgct
     7921 caaggattgt acgaaagcaa gtttctaagc tatccaagaa cggattcctt ttacattaca
     7981 gaaaatgagc atcagtatct ggttaaacat ctgcaaaatt ataaaaaatt tttaggaata
     8041 gaagaagtac agacaactga gatcaaagca aagaaacgat atgtcgatgc gaaaaaagtt
     8101 caagaacatc atgcaattat tccgacaaag acgattccga ctcctgcacg ctttgcgaag
     8161 ctttccaaat tacagcaagc aatctatttg caagttttgc gcactactgt ggctatgttt
     8221 gctgcagatt atatctacga agagacgacc gtaatgacgg gcgtacagca attaaagcta
     8281 aaaagcatcg gaaagatccc attacagcaa ggttggcagg aaatcttacg catcaagtca
     8341 aaaaagaaag aagctcagac tcttcctcct atcgtagaaa atgaagaagc agaagtagaa
     8401 ctgaaaagta tggagaaaga aacacaacct ccaaaaccct ataccgaagg aacgttgatc
     8461 acagcaatga aaactgcggg aaaaacgctg gataatgatg aagcgcaaga aattctcaaa
     8521 gaagtagaag gaatagggac agaagctaca cgagccaata tcattgaaaa tcttaagcag
     8581 aagcattaca tcgaagtcaa taaaaacgaa ataactgtta cgccaaaagg aatcactctt
     8641 tgtaaggcag tagccaatga accattactg acgagcgcag aaatgactgc gcgctgggaa
     8701 gggtacttga gaaaaattgg taaacaagag gggacaccat ctgttttttt agagaatatc
     8761 aaaaaattca tcctacattt attggcagaa gttcctaatc aaatcgacaa ggtagacttt
     8821 tcagatgaga ttagcgggac acgtcagata aaagcgatgg agaagaaaaa cgatcaatta
     8881 ggaagatgtc caaaatgtaa aaagggaata gtcatgcttt atcctaaaat cgctacatgc
     8941 ttgaatccgg aatgcgactt caaattgtgg ccaacagtag ctaaaaagaa gctgactaaa
     9001 acgaatctca gagatttgct ttcaaaagga aagacaagta aagttgtcaa aggttttact
     9061 ggtaaaaaag ggaaattcga tgcagtttta gtattaaaag aagatatgac aatcggtttt
     9121 tcttttccat ggatcgaaaa cagtggaaca aaagcagttg atggaaacaa agaaacatca
     9181 agaaaaaata atgaaaacga agtagagtaa atgaaaacaa tgaaatagcg gaatatttat
     9241 tccgaaaagt gagaatataa ataccaataa aactaaaaaa tatcagtgaa tcaagcaaaa
     9301 acgttggggt aggctgattt tatatagata gcaaggagtt tttttatttg aaaaaagtgc
     9361 attcattttt aaattatctt atgggagcaa tcacgattgt ggctgtgtac caagcatttc
     9421 taaagtatcc tgattacggg acgaagttgt tgtcattgac gcacaatcaa acagcatatt
     9481 caccaacgtt gattttatcg actttgactg caggagctaa aagcgctact tatttttttc
     9541 ataaaacgac aagcatgcta aagcgaaaga aacagcgaaa acaattgttg gtggtggtag
     9601 cggctatgat cattatttat tttctaccag ttattacaca agtatttcat caatattttg
     9661 gttaagaata cgagagtttg tgacaaaagt catgtcacaa acttttttct ttgtcatttt
     9721 ttcgtaagaa aaagcaaaat aaaagtatat acattgatta aaagtatata cttggatata
     9781 atgtacttac tatagaatga gaatggtata gagggtggcg aaatatgaaa aaaatgaaaa
     9841 agtataaaat tagaaaatct ggcaatagcg atgtaacaac tatcccacca gaagtaaaag
     9901 aattcatggg tgtgcagaca ggtgacgcaa tcagttatgt ttttcaatct gatggttctg
     9961 tacgaatgat caaagcacaa gaagaacctg atattgattc attagttgat tcgatcatga
    10021 atcaatatga agacgcgtta aaagatttgg ttgatttatg aggtatcttt cgactaaaga
    10081 aattatcaaa atcaacgcga aagttatttt acgtcactcg ccaggcgaaa tgatcggtgt
    10141 aaaagatgca aatgcattag atatggccgt caaacagcct tcacaagcag tattcaatca
    10201 agaactctat cctgaaatct atgaaaaagc ggcgatttta gcaattaatt tagctaaaaa
    10261 acatcctttt cataatggca ataaacgaac tgctcttgtt gccatgttgt tgtttcttca
    10321 attgaataat tgtccagttg ctttttctcg tcaagaagct gttgatttta tcataatgat
    10381 taccactagt tcattggatt tcgattcact aaagtccaag ataaccagtt atttacgaca
    10441 aaccgcaata aaatgaacga attaaaaact ttatttctca attagatcag catgtcatta
    10501 aggaatatgc tgattttttt atgtttaatc atacaaaata gttttttcat aaaaatatgg
    10561 aaaatatgga ttaattttga aataattgat ttaaaaggaa tacaaaagag tgaatagtag
    10621 gaaatagtgg tttagaacta gtgggctgat tttttatata tt
//
LOCUS       DADVXM010000082        10291 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.087, whole genome shotgun sequence.
ACCESSION   DADVXM010000082 DADVXM010000000
VERSION     DADVXM010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.087"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            172..321
                     /locus_tag="KB927_002241"
     CDS             172..321
                     /locus_tag="KB927_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBB6841139.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            332..1846
                     /gene="dltA"
                     /locus_tag="KB927_002242"
     CDS             332..1846
                     /gene="dltA"
                     /locus_tag="KB927_002242"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBB6841140.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            1843..3048
                     /gene="dltB"
                     /locus_tag="KB927_002243"
     CDS             1843..3048
                     /gene="dltB"
                     /locus_tag="KB927_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBB6841141.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            3093..3326
                     /gene="dltC"
                     /locus_tag="KB927_002244"
     CDS             3093..3326
                     /gene="dltC"
                     /locus_tag="KB927_002244"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBB6841142.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            3329..4597
                     /gene="dltD"
                     /locus_tag="KB927_002245"
     CDS             3329..4597
                     /gene="dltD"
                     /locus_tag="KB927_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBB6841143.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            4738..5820
                     /locus_tag="KB927_002246"
     CDS             4738..5820
                     /locus_tag="KB927_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBB6841144.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            5820..6623
                     /locus_tag="KB927_002247"
     CDS             5820..6623
                     /locus_tag="KB927_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBB6841145.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            6693..7433
                     /locus_tag="KB927_002248"
     CDS             6693..7433
                     /locus_tag="KB927_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6841146.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            7444..8448
                     /locus_tag="KB927_002249"
     CDS             7444..8448
                     /locus_tag="KB927_002249"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBB6841147.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(8493..10190)
                     /locus_tag="KB927_002250"
     CDS             complement(8493..10190)
                     /locus_tag="KB927_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841148.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT         3308 a         1702 c         2085 g         3196 t
ORIGIN      
        1 tttaaaagta cgagaaatta taaagaaaaa agcagtgatt tgatgtgcta tttttataaa
       61 agctatgtga caaaactgtt agtaaaaaaa cggtttctgt aagctagaca catgtttctt
      121 tttgtcaaaa ttagttacac tttgtgtgag gttatatgag gagggaatcc aatgaacaaa
      181 tggcgttcta atccaaaatt gaattattgg ggaaaattca tcattcgaac aattttttat
      241 agtgcagtac tgctgttcct gatttatctg tatcactata aaaatattca aggaggaact
      301 tttatctata acgaatttta ggaggaagag tatggaaatc aaaacgatta ttgaagcaat
      361 cgatgattgg ggaataaatg aacctgatcg agttgcttat caggcggatg agacgcatac
      421 ttttggtgaa ttgaaacaag catcagacgc acttgcttat tatttagaaa aaaaggtaga
      481 aggcgatgga ccaattgtcg tttttggcaa tttggagttt gaaatgattg tctcatttct
      541 aggggttgtc aaatctggcc atgcctattt gccgattgaa gagcatacac ccaaggagcg
      601 tatcctatcg atctttcggg tggctaaacc atctatggtc atcagtatcg gggactggat
      661 agaagatatt ccttcggttc ctgtcataac aaaaaaagaa tttcaagaaa tcaagaagat
      721 accagtagga ttttatccca gaaatagcgt aaaaggtaca gaaaattttt atattatttt
      781 tacttctggt actactggag aaccaaaagg cgtacaaatc agtcatgata atctagtcag
      841 ctttgttcaa tggacgatgg aagactttgg gatcaagcct ggtatgcatt tcttagccca
      901 agcgccattt tcttttgatt tatcggtatt ttctatttat cctgcattag tttctggcgg
      961 aatgctgaag ccgttaaata aagcagttgt tcaagacttt cgtcaattat tcgcgacatt
     1021 gccagccttg aagttgaatg tgtgggtttc tactccatca tttatggata tttgcttgat
     1081 ggaacctaca ttcaatggag aaaatgtgcc ggaattggac atgtttttat tttgcggaga
     1141 agaattgacg aaaaaaactg cagaaagtct acttgatcga ttcccaaatg cacggatata
     1201 taatacttac ggtccaacag aagcaactgt agctatttca agtattcaga ttgaccagca
     1261 tgtactagat agttatgacc gactaccgat tggctacgta aaaaaagaca cgaaagtttc
     1321 tattgtccaa gaaggtaaac ctgtttcaaa aggagaaacg ggtgaaatca ttattgcagg
     1381 accaagcgta tcaaaaggtt acctgaacaa tcccgaaaag acagctgctg cgttcttttg
     1441 tcaaaatgac ttagcaagtt accatacagg ggatgcaggt agactagatg aatatgggct
     1501 tttattttat gaaggacgta tggatcagca ggtcaaatta catggatacc ggattgaact
     1561 cggggatatc gaacattatc tgctccaaga caaccgaatc aaacaagctg tcgtcgtacc
     1621 aaaataccaa ggaacaaaag tacagcagct ggttgctttt gtcgtattag aaaacaaaac
     1681 gaaacagccg gattttcagt tgactaaatc tatcaaagaa caattactag aagttgtaat
     1741 ggattatatg attcctcaga agttccatta tgtcgatctg ctgcctcaga cagttaatgg
     1801 aaaaatcgat cgaaaaaaat taacagctga ggtgaatcct gaatgatgtt acctcatatg
     1861 atcccttatg cagagccgtt ttattttttt cttttagcca ttgcgcttgt accgatcgtt
     1921 ctatctttat tgatatggga aaaaagatta ccagtttatc aatcagcagt gacacttttc
     1981 tttttatttg tcagctttgg aggtaattat tggcaacagg gagcggcgct gattgggtat
     2041 gttttgtggc agacgatact tgtatggggc tattttgttt atcggcaaag gaaaaatcag
     2101 acaggatggt tttttgccgc cgttatttta gcgataattc cactgttttt aacgaaagtg
     2161 actccttttt ttgaacatgg aaaagcatcg ttacttggtt ttttaggaat ctcttattta
     2221 acctttaaat ctgtacaaat gatcatggaa ataagagatg gcatgatcaa aacatataag
     2281 ccatttcgtt atatccagtt tctgctgttc tttccaacaa tctcttctgg accaatcgat
     2341 cgctatagga gatttgaaaa agatcagctc catccgcctg ttcgtgataa atatgttgat
     2401 cttttgggaa aaggcgtcca aaatattttt gtcggttttt tatataaatt cattatcggt
     2461 tattattttg gtcaagtact gcttcctgta gtgggacgca ttgccttaca gcatggtggt
     2521 atttcatggg cattagtagg ttatatgtac gtgtacagta tgtatttgtt ttttgatttt
     2581 gctggctata gcttatttgc agtcggtaca agctacatga tgggatatca gacaccaatc
     2641 aatttcaata aacctttttt atcatggaat atcaaagaat tctggaatcg ttggcatatg
     2701 acgctgtcct tttggttccg tgattatgta tatatgcgat tgatgttctt catgatgaag
     2761 aaaaaatttt ttaaaagcaa gatcgtaatg tcaaatatcg gttattttgc tttgtttctt
     2821 ctaatgggta tatggcatgg attgacgtgg tactacatcg tatatggact gtatcatgct
     2881 tgtctgatct gtctgacaga tgcatggatc cgatttaaga agaagcataa agagcagttg
     2941 ccttctaaca aatttacgca tggcttagcc gtatttttga catttcaagc agtatgtttt
     3001 agcttcctga ttttttcagg atttttagat aaactttttt ttagctaacg aatagtgaca
     3061 tattaattta tataacaaag gagaaaagga aaatggaaga acaaatttta tcaatcttag
     3121 aagaaataac aggaacagat gaagtaagaa aaaatcgtga tattgatcta tttgatgaag
     3181 ggttgcttga ttctttagca tctgttcaat tattagtcga gctagacgga gagctggata
     3241 tccaagtccc tgtatctgaa ttcgagcgag aggattggag cacaccgaat aaaatcattc
     3301 aacaagcaac tgcattgaag ggttgagtat gaaaaagaaa ctttttgcta ttttcggccc
     3361 ggttgtttta gctgttggct tactgtttgt gttttttacc tcctcctatc aagtagatat
     3421 ctctaatcca gaaacgatta gacgtgcctc ttcttccatg tcagtgaacg tgttgaaagg
     3481 agatgcgata aaaaattatg cattatctga aaaacaatat attccttttt ttggctcaag
     3541 tgaattaagc agaatcagtc catttcatcc gtctgttctg gcagaaaaat accagcgaaa
     3601 ctatcgtcca tttttgctgg gagcacccgg gacacaatcg ttaagccaat atatgatgat
     3661 gcgttctgca ggagatgcta tgaaaaacaa gaaagtcgtc tttattattt ctcctcagtg
     3721 gttcgttaaa aatggtgtaa aaactgatta ctttaatacg tattattctg aacttcaaac
     3781 atacgactgg ttgttttcaa tgaagaaagt aacgcctgct gatcgctatt tagctagaag
     3841 attattaact ttctcaaaag taaaagagaa tgatacgttg acggcgattc tgcaaacgat
     3901 caaaaaaggg aagctacctt tacctgaatc tttgaatcag ctgcgcagcc aatggaacat
     3961 gctgaagaga gaggatgaag tattcagcaa tattgggttg aaagatcgac agcaaaaaat
     4021 cgatcatgag tcaaaacgat taccaaaaca ataccaagaa acagaattat ccattttagc
     4081 aaatcaaatt ggagaacgag aaacgacgaa taatccattc gggttgaaaa acgattttta
     4141 tacgcatcgt atccgagccc acgagccaga gctcaaacag tcacaaaaaa attgggatta
     4201 tcgtttttcg ccagaatttt ctgattttca gctggtcttg gatcaattag caaaaaacca
     4261 taacgaagta ttgttcatca tcccaccggt taacgagaaa tggagcgatt ataccggact
     4321 atctcaagaa atgttacaag gatttgccaa aaagatcaaa tttcaattaa atagccaagg
     4381 attcaatcga atagctgatt ttgtcaatca agcgggtacc aactatttta tggaagacac
     4441 gatccatcta ggctggaaag gctggttggc tgcagatcaa cagatcagac cgtttttaga
     4501 agaaaatcat attactgcta gtaagtatca tcttgacgat gcttttttta gcaaatcttg
     4561 gcaacatcaa ataccagata aactacaatt aaaataaaga aaacaggcga gtgttgctcg
     4621 cttgttttct ttatttttga atattctgaa taaaagataa aaataccaag tttgcctgaa
     4681 caaaaatcat aagcaatggt ataatcacaa tatgaatata gaaatggggg aaaacatttg
     4741 gatacaaaag aagaacagct acttattgat ttaacttctg caaaaggagt acctggaaat
     4801 gaagaagagg taagagaagt attcagagaa tatgccaaac cattcgctga tgatattttt
     4861 tatgacggtt taggcagtgt gattgccaaa catggtgctg gcggaggccc caaggtcttt
     4921 atttctggac atatggacga agttggtttt atggtaacaa aaataaccga aaaaggattc
     4981 ttggaattcc aaactcttgg aggttggtgg gggcaagtca tgcttgctca gcaagttgaa
     5041 atcaaaacac gtgaagggaa aatcgtccac ggtgtgattg gttccaaacc accacatgtt
     5101 ttaacacctc aagtaagaaa taaaccttat gaaataaagg atatgttcat tgatattggc
     5161 gcatcaagcc aagaagaagc caaagagtgg ggcatacgtc ctggagatat ggtcactcca
     5221 tatattgaat acaaacgaat gaatggcagt aaatatttac tggcaaaagc atgggataat
     5281 cgtatcggga cagctgtttc tctgcgagta ttagagaatc tatctaaaga agcacaccca
     5341 aatgttttat tcgcaggaag cgatgtgcaa gaagaagtag gcttgcgagg tgctcgaaca
     5401 agtacacacc ttgtaaatcc cgatattgct tttgctttag atactggtac agcaggagac
     5461 actccaggaa tgacaccaaa agaagcagat tcgattttag gaaaaggccc acagattttg
     5521 atttttgatg catctatgat cccgcataaa aaattattga attttgttat tgatgtagca
     5581 gaggaaatgg atattccatt ccaatataca gtgatttctg gcggaggaac tgatgcagga
     5641 caaatgcatt tgacaagaga tggtgttccg tctgtagcca ttaccgttcc tgttcgttat
     5701 ctgcattccc atacatcagt gattcatgaa gatgattatt tgaatacagt gaaactagtc
     5761 acagaattag tgaaacggct tgatagtgaa acagttgaaa aaattcggag ttatgaataa
     5821 tgaataatag aatacctatt tctgaatatc ggaaaaaagc acgagtttct ttggaaaatc
     5881 aatggggaat caatacttgg cttgttttct tatctataat atttacgagc gtcatccaga
     5941 acttttttga cggtttcagt ccttttccgg aagaaagcat gcagcagcac ttattgagtt
     6001 ttctagtcga taatttactt ttattcgcat tcaactatgc attgttttac attgcgctag
     6061 tagttgtacg gggtggcaga ccaaaaagta accttttatt ttcagttttc caaagaaagt
     6121 attttggttc gatacttggc atcaatttga tcaattcagt catcaactgg ctactcaaca
     6181 gtttaatctt tctgcccatg tttttaatca gcggagtgag tacttatatg cagctgcttt
     6241 tcagttcaaa tgcggtacct acgggtgtca tgccagaaga ttttcttgat atcagctttg
     6301 ttttatcgat gatagggatg atttttgttt cagcactcat catgagtatt gttggcggtt
     6361 tattccaatt tgctgcatgg acaaagttcg actatcctga tttgtcggtt attcaatgtt
     6421 tgaaatatgg ctggttttta ttgaaagata gaattggtac gtatattttg ttgcagctgt
     6481 cttttatcgg ctggtatttg ctaggagcaa tcgctttgtt catcggtctt ttgtgggtca
     6541 ttgtttatgt gaatgtgtca gttgcagaat tttatgaaca agcacggatt gaaaaaggag
     6601 gtccagacgc ctattttact tagcatgtaa gcagtttatt catcaaaaaa ataacttttg
     6661 tggtaggata aatctttgag ggggaatgta cgatgaaatt aactgtttta ggatgcttag
     6721 gagcgtatcc ttataaaaat caagggacaa caggttattt gcttcaatct gacgggttca
     6781 atttgttgat cgatgcaggt agtgctacgc tgatcaaatt acaagaacac cttgatccac
     6841 ttgatctaga tgctgtgatc cttagccatt atcatcatga tcatattgct gaccttggtg
     6901 tattacagta ttactggcaa cttcatccta agagaaatcc ggagacattg ctttcaattt
     6961 atggacacac aaaagattcc attcactttg aagaattgac gttggaaaat gtctcaaaag
     7021 gacatcctta ttttgaagct gaagaattaa aaattggtcc ttttctgatt acttttatgg
     7081 aaacaatcca tccagtagta tgttacgcca tgcgtatcgt agaagaaaca acggggaaag
     7141 tattcgtatt tacaggtgat tcaggttatt tggaaagttt cgctgatttt gcgaaagatg
     7201 ctgatttgtt tctagcagat acctatcttt ttgaaggaaa tgaacatcat catgcccatt
     7261 tcacttcaaa agaagctgga gaacttgcga aatcagctaa cgtaaagaaa cttgtactta
     7321 cacacctacc tcagtttggt gatttagaac aattgaaaaa tgaagcgcaa aaggcagcag
     7381 gcaaagggat tgatatagaa cttgctgcag ttgacaaagt gtttaacatt taggaggaag
     7441 aacatgattt ttgtaccaaa tgaaaaccac gacccaagaa tcaatttagc aattgaacaa
     7501 tatttgctgc aagaaatgcc tttagatgaa cctattttgc tcttttatat caatgaacct
     7561 tcaatcatca tcggcagaaa ccaaaatacg cttgaagaaa tcaatcgaga ttatgtggaa
     7621 gaaaatggca ttcatgttgt ccgtcgctta agtggaggcg gagctgtcta ccatgatttt
     7681 ggaaacctga actttagttt tatcatgcct gatgatgggg attcattccg tgactttgcg
     7741 aaagtaacac agccaatcat ccaagcactt catgaattgg gtgttgctgg ggcggaattg
     7801 aaaggccgaa atgatctagt cattgatggc atgaaatttt ctggcaacgc gatgtatgct
     7861 accaacggtc ggatgtttgc tcatggaaca attatgttcg actctgatat caatgaagta
     7921 gtcaatgcat taaaagtaaa aaaagacaaa atcgaatcaa aaggaatcaa atcgatccgt
     7981 tctcgtgtaa cgaatatcaa accatttctt ccagaagaaa agcaaaaaat gacaacagaa
     8041 gaatttcgtc aagaaatctt gttgaaaatt ttcggcgtag agtcagtaga agaagtaaaa
     8101 acgtacgaat tgactgatga agattggaaa aaaatcaatc gaatctctga ggaatattat
     8161 cgaaattggg attggaatta cgggaagtct ccagatttca atttctctcg ccaaaaacgt
     8221 ttttctatcg gttcgattga agtccatttg aatgtctcag aaggaatgat caaagaagca
     8281 aaaatctttg gcgatttctt cggactagga gatatctctg acgtggaaaa aaaattggtt
     8341 ggacagaaat atgataaagc atctctatca aaaatagtca gccaaattga tgtgaagaaa
     8401 tattttggtg cgatagaacc agaagaattg cttaccttac tttattgaaa ataaaaaata
     8461 gcggaatcca catatatgga ttccgctatt ttttatacag gattcgggta atttcgagag
     8521 agttgaacag tgatccgatc aatgaaagta tctttttcct gcgttagtgt tcctgtgtaa
     8581 cgatccgcta cgtctttcat catcattaag tcaaaacgtt cctgatcatc taattcttct
     8641 gtgatgcctc gactaaatag gtttgtatcg taatgtgcac tatgttcgca acaaatgacg
     8701 aaatgttcct cttgttcgtg tatcgacaaa taaatttttc gatacagtgg attttcgatg
     8761 gcatgagttt ctctaaagga atgctctaaa gcgtggatca aaagttgagc cagatcgtca
     8821 tcgttgatag gaagttcttc gggaagatct gcttggaagg ttatctgaat attccgtttg
     8881 gcagctaact tctggtaacg cgctaagata agatttgtca cctggtggtt gcaaaaagaa
     8941 cacagcattt cgaaattttt tgcttcttct aatatctttt ccacatagtt tttagctttt
     9001 gtttggtccg tatgcattaa atcttgcaga ttctccatct cttggacaaa ttccaggcga
     9061 agtgtattta cttcttggat atgctgtcga agctgctcat aatgttgctc caacaaatca
     9121 tttttgattt ttaagaaatc tacttgtctc cgatctttgt cggtatttaa gatgtgatcg
     9181 attagattgt agctgataat aacgattaga atgataatat ataaaatcgt agaccaattg
     9241 atcgttgttt gatagatacc taatgccgtt tggatgtaaa tcaagcaatg gataatggct
     9301 accaagacga tccaaggtgt acaagctaca taaaaacggt tattcttata tgcttcgcca
     9361 atgcatgcaa gtgaagtgac taaagtgctt ataacactag caatattagc aatcggcatt
     9421 aattcaggaa gttctgcagg agtaaaagtt gcataaagca gaacgccgat aaaaatcaaa
     9481 agttggaacg tacaaaaaat tccgtaccat tttttatagt aaaacattcg gctccaatag
     9541 tagcagatga tgaaagctga cgttaagata ataaataaat gagataaaaa agaatgaacg
     9601 aatggttcaa aaagaatacc acttaaaata tcttctgata cagcttcaaa tcctaatgcc
     9661 aaagcaaagc aacttaagag aataagtgag tattcaagac gtttttgttt atacatcaag
     9721 tagatcgtat agaaaaaggt ccctatagcg ataaaaacag cgattatcat cgtcaatact
     9781 tgcggcactg attgtgaata aataaaacta atcaatggtc cagttgttcc tagataaact
     9841 ttcggtggca gtccagcata gttctgataa ggagatgaga ctgtaagggt caattttttt
     9901 ccgatataat ttgctggtaa atctatcaca gccaatgaga gtccgggatt gctttcttcc
     9961 tgataatctt tccgttggta taaaatcttt tcgcctagat atacagtaat ccattgatgg
    10021 tttcctttga ttagtaaatt tgcttcgtcc aacggttttt caagtgtcgt ttccataatg
    10081 aatgtttcgt ctttatccac ggtaggaatc gtacgagtgt acttgctgtc aaacttaaaa
    10141 tcaggatcat cttttgtata gaaaacccac gaatctttta tttctttcat ttgattgctg
    10201 tccgcaggag aaaaaataaa ataaaagaaa taagcaattc ctgttaaaaa taacaatgat
    10261 aatataatga ttatgctcca ctttatacgt a
//
LOCUS       DADVXM010000083        10022 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.088, whole genome shotgun sequence.
ACCESSION   DADVXM010000083 DADVXM010000000
VERSION     DADVXM010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.088"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(486..710)
                     /locus_tag="KB927_002251"
     CDS             complement(486..710)
                     /locus_tag="KB927_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841149.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            901..3678
                     /locus_tag="KB927_002252"
     CDS             901..3678
                     /locus_tag="KB927_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6841150.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            3759..4178
                     /locus_tag="KB927_002253"
     CDS             3759..4178
                     /locus_tag="KB927_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBB6841151.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            4190..4660
                     /locus_tag="KB927_002254"
     CDS             4190..4660
                     /locus_tag="KB927_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6841152.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            4677..5456
                     /locus_tag="KB927_002255"
     CDS             4677..5456
                     /locus_tag="KB927_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6841153.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            5443..6264
                     /locus_tag="KB927_002256"
     CDS             5443..6264
                     /locus_tag="KB927_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6841154.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            6281..7330
                     /locus_tag="KB927_002257"
     CDS             6281..7330
                     /locus_tag="KB927_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6841155.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            7343..8347
                     /locus_tag="KB927_002258"
     CDS             7343..8347
                     /locus_tag="KB927_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6841156.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            8980..9999
                     /locus_tag="KB927_002259"
     CDS             8980..9999
                     /locus_tag="KB927_002259"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBB6841157.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         3362 a         1651 c         2094 g         2915 t
ORIGIN      
        1 taatttgttc ttgcaatctt ttttgctacg taatttttgt aaaaaagtgg gttgagagaa
       61 atctaattga ttttcaaaga aggagtatga aaatgagaaa aatatttatt cgtttattgt
      121 gggtactatc ttagaggaat aaataatagt ggagaaaact atggtttggc gcagattcta
      181 tcaggtttga tggaacgaag acaacctccc gacatcaagt caaaagctac ttgagatttt
      241 gatctgaaaa taaaaaaaga aaacaaggta ggaacatcaa tgtttctacc ttgttttcgt
      301 aatcaatggg aaaaaactaa gagtggtgta cgtaatcaat aaaaaggatg gtgacaacag
      361 tacctcttta ctctctgaaa gcatcataac tcgtttttcc tcattatgcc aataaattgt
      421 tgttatacca catataagga tttgtaatag ctaaaaacag acaggaaagt tgaaatctgt
      481 gaatcttatt ttgtatggaa ggatttatag aacgcaaaaa tcaagataaa gatgaataaa
      541 aatcctgttt cggctatata ttgcgtatct acgccaataa aacgagtttg ttctgtcata
      601 gccatataaa gcaaaggcaa aaatacaact acagcgagat aagatccgat gatttctcga
      661 aaagttttcc aggaagtatg tttcctgttt ttatatttat ccgatttcat tgaatagtca
      721 tagcctcctt attctttcat atgttgaaat tccagtataa aaactggaag gaactgtacg
      781 ttttttagaa taaaaattat aagggataag taggctgctg tctataataa gatatatttt
      841 tcaattcttt attaaagatt ttattgacaa aatgaatccg ttttctatga tggaggaggg
      901 gtgaataagt tgttgaagaa ggaaatttta tgttacttag agaaccagac agcctttttc
      961 gatttagaac atatgaacga ggtctttaca gcacaaaggt tagctgatca ttttggggta
     1021 aaaagaaaca cagtcagtca ttatttgaac cagttaaatg atgagcaact actagtcaaa
     1081 atcaattctc gaccagtgat ttatttccac aaagaagctt ttgaaaaaca attttttaag
     1141 ttacgcacga atttttattt ttctatcgat gatctcaaag aggaacagcc ttttttcgcg
     1201 caaccaaaag acttattctc ttttatgatc ggatacgacg ccagtttgaa agaaagtatc
     1261 gaacaaatca aaacagctct ttactatcca gatggcggat taccactttt gattacaggc
     1321 gaaagtggca caggtaaaag ttatttagtt aatttggtct atcagtattg tctgcttcat
     1381 gatctgctag aagattctgc accattcatc acttttaatt gtgcacaata tgcagataat
     1441 cctgaacttt tgactagcaa tttgtttgga catgttaagg gagcgtacac tggtgcagaa
     1501 gaaaataaaa aaggggcttt tgaagcagca gatggtggga tcttgttttt agacgaggta
     1561 catcgcttaa caccagaagg tcaggaaaaa ctgttcacct atcttgatca aggtgtgatt
     1621 tatcgtatgg gagaacctaa tttgtcacgc cggatcaaaa cacgtctctt ttttgctacg
     1681 actgaagaga ttactagtca tttcttaaca actttcattc gaagaatacc tatccgaatc
     1741 gaactacctg cacttaatca gcgtagtcgt aatgaacggc tagaactgat ttactctttt
     1801 tttctcgaag aacaaagaaa aatggggagc cctttgtcag tcagtggacc agctttgtca
     1861 cttttaacaa gtcagaaatt atccggaaac ataggagagc tgaaaaatat cgtcaaagtt
     1921 tcagcagcaa aagcatatgc tgaacagcgt gaacagcctg aaatccatgt cacgatccat
     1981 catttgcaaa aagaactact tgcgcagcct attactaaaa atacagcaca gcaaggaatc
     2041 tatattacgc aagaccagac cttagagcaa ttaatggaga agcaacagcc cgaacagcag
     2101 cgaatcgtta aaagttttga gcaaatccta attgatttca agaaaaataa ctgtctgcta
     2161 tattcttgcg aaggaaaatt aaagcaagaa gtgattcaat tatttgattt tttgctgttt
     2221 gagaccagta gacaagaaaa acacgagctg ctggtttatt ggacacaatc tatccgagag
     2281 acctttcgac aaatggaaac tgcctatcaa atcaaattcg atggaaacag tgtctatgcc
     2341 ttgagttact atctctatca gcgaagcact atcaaatggt taccggaaga acatgatatt
     2401 atccaactaa tcaaagaatt agaacaacaa gtttctcagt cttatccatc tagttatcac
     2461 tatgtccaac gaattctgga attaagtaag atcaaattag atattgaaga cacaagtatg
     2521 gatcggattt tactgacgat ctatctaaaa aaagcgaaat ggtcaaaaga aaaacgactg
     2581 ccaaaagcga tgattgctgc tcacggttat gcaactgcta gcagtatggc aaatgtagta
     2641 aatcgtttat tacaagagga tctatttgaa tcatttgata tgccactaga tgtcacacca
     2701 cagcagattg cttcagaaat ccttgattat tgcgaaaaca gcgatgtttc aaatggattg
     2761 atcatattag tagacatggg atctctgaaa gaaatccatc agttttttaa aaaacagtta
     2821 tccgtaccgc ttttgatttt gaataatgtg acgacacctt tagcaatcac agtaggggaa
     2881 tgcctgcaaa aaaatgtatc attagaagag atagcagaag agactgttcg acagatccag
     2941 ccagaatggc gactgctcta tccagaggaa aacaaaccca aagcactcat tactacttgc
     3001 ttcactggaa tcggtacggc ggtccactta agtgaactgc tagaaaaaag cttacctacg
     3061 gcttgtcagt tgaaaatcat cccatatgaa tatcagcaat taaaagataa gaaaaacagt
     3121 gacccattat tttccatata cgaagtcgta ggaatgattg gcaccacaga tcctgatatc
     3181 accaatatcg actatctttc attagaagac ctcatctcgg gggaaaagat gtctgtacta
     3241 gctgaatggt tggacactac tatgaatgct tcagagaagg aaatattcaa tcagcgcatc
     3301 attcgtaatt tttcattgga aaaagtactg gattccgtga ctattctaga tacagagaag
     3361 gtgatgggag aaatcgatca ttttatgaga gaattagagg tgcagttgaa tcgaagcatc
     3421 agcaatccca aaaaattagc gttgtatgtc catgtgagct gtctcattga acgattgatc
     3481 cgacaaatgc caatcgaaac ctatcaagga ttagagaaat ggaagcagtg tcaaaaagaa
     3541 gggttatctg ctattaaatc tgcgtttagt gtcattgaag agcattatag tgtcatgatc
     3601 cccaattctg agattgccta tatctatgat attttgagtg aagatacaga gtttctctcg
     3661 atagaagaag aattttgaac ataagcaagt tgttgccact aattttggca tgcaacttgc
     3721 ttttttagta tgtgtaagtg aaaagaggag atgaaaaagt ggatagagaa attatcttag
     3781 cttcccatgg aaaatttgct tcagggatat tagattcatt agagctgatc tatgggaaaa
     3841 atcattctat tactgtattc gattgctata ctgatgagaa ttttgattta gcggaaacag
     3901 taaggcagct ttttatgagg tacaaagata aagaaatcat tgttctgacg gatctttttg
     3961 gcggaagtgt caacaacgaa ttcttacaat atatcaatcg ggatcatgtc tatctcgttg
     4021 ccggattgaa tttgccacta ttgattgagc tagtatctcg gttggacgct gaagtagaga
     4081 caactgtttt gatccagcag gtgctaactg attcaaaaaa aatgatccag ttttgtaacg
     4141 agcggctcaa tcagaaaata gaagaagacg aattttagga ggaagaaaaa tgattgtatt
     4201 gacaagagtc gaccatcggt tattacacgg acaagtagct ttttcatgga cacaaacaat
     4261 aggcgcagac tgtattttga ttgctaatga tgatgtacct acgaatgaga tacgaaagac
     4321 aacgatcaaa ttagccaagc cacaaggagt caaactagtg atcaaatcaa ttgatgactc
     4381 gattgccgcg ttgaaaagcg gggtgacaga taaatataag ttattcatcg tagtggaatc
     4441 gatcgaggat gcatataagc tggcagaagc gtatccagaa atcaaaacca tcaacttagg
     4501 agggatcaag gcaaaacctg gtactcgcag catcggaaaa gcggtaaata ttttaccaga
     4561 agaggaggaa cgcttgaaac gattaattga caaacaaata gaagtagaaa tccgtcaagt
     4621 accagcagat aaaaaagtgg atgtaagaga agttttgtaa gaaaggaaga acctcaatga
     4681 ttgtacaagc agtcttatta ggaattgttg catttgtcgc acaatcagaa tatgcactag
     4741 ggacatcgtt gctttctcgt ccgattgtga cggggctgtt tacaggaatc gtgttaggtg
     4801 atgtaaaaac tgggatcatt atgggcgcaa ctttagagtt agcatttatc ggatcgttct
     4861 cagtaggtgc ttcgattcca cctgatgttg tgaccggtgg gattttaggg acggcttttg
     4921 ctattacagc tggagccggt acagaaaccg cgcttttact aggtttgccg attgctacgt
     4981 tgacattgat attgaaaaat atttacttag ggcttttgat tccaattatg aaccataaag
     5041 cagacaatta tgcagaagaa ggaaattata aaggagtcga gcatatgcac ttgcttgccg
     5101 gtatcggtct ttccttgatg cttggtgttg tggtaatggt ttcttatatg gtgggaagca
     5161 atacgatcgg aaatctatta aatatgattc ctgacttcgt tcaaaagggg ttgtcagtag
     5221 ctacagggtt gattccagct cttggttttg cgatgcttgc tcgtttgctg atcaacaaac
     5281 aagttgcacc atattttttc ttaggttttg ctatagcttc ttacttagag attcctgtga
     5341 ccggagtagc tatttttggt gcgattttag cagttgtggt agtcaatatt atgaatgtcc
     5401 gtcaactacc acttcaaaca actgcagggg aggtagaaga agatgaagaa ttctgagatc
     5461 aaaaacagca aaataacgaa aaaagagcta aatcacgtat tttggcgttc ttttcaaatg
     5521 gagttttctt ggaattatga acgtcagatg aatatggctt atgtttatgc aatgattccg
     5581 attttgaaaa agttatatca gtcgaaagaa gaaatggcag cagctttgaa acggcatcta
     5641 gagtttttta acacgacccc acatatcgtt acactgattt taggaatcac ggctgcaatg
     5701 gaggaagaaa ataaggatga tcctgaattt gatgtgactg cgatcgatag tatcaaaaca
     5761 tctttgatgg gacctcttgc agggttagga gattctttct tttggggaac tttgcgattg
     5821 attgccacag gtgtgggtac ctctttagcc atgcaaggaa atattttagg ccctatcttg
     5881 ttcattttga ttttcaatat tccgcacatt ctgtttcgct atctagcaac aggttgggga
     5941 tatcgcttag gaacgggttt tttgaaaaag atccaggcaa acggtatgat ggaaagtttg
     6001 acattaggcg cgtctattat tggactgatg gtcgttggag caatgactgc cacgatgatc
     6061 accatcaata ttcctttaaa aatcggttca ggagaaaatg ctgtgactgt tcaaagtatt
     6121 tttgatgata tcgttccaaa tatcttatgt cttggagcat ttggcatagt gttttatcta
     6181 ttgaagaaag aagtgaaacc attaacgatc ttgatcggac tagctttctt tggaattttt
     6241 ggttcgtgga tagggatttt ttaaaaaagg agcagagaaa atgtttacga tgcaagatta
     6301 tatctatgaa gaaaaggaag tactaagtac gatcttgaaa aagaatgatt tttcgacaag
     6361 agaacatatg aaaaaaacag tgaatttact gatcttagca acgggttcat cttataacgc
     6421 ttgtttagca gcgaagccag cattggaatc ttatggtgat cttactgtcg atattcaaga
     6481 acctttttat tttttcaatt atggaaaact ttctccttca atcgatactg tgattgctgt
     6541 gtcacaaagc gggaaaagtg cttctactgt tgaagcagta aaaatgatac aaaaacaagg
     6601 gttacctgtt gttgctatca caaatgacgt gcaaagtcca cttgctttag aagctgcaca
     6661 aattattgat ttaggtgccg gggtagaatc agtaggcttc gttacaaaag gctattctgc
     6721 gactgtttta cagttactac tcttagggat aggaattgga ataagtaaaa ataaaatcag
     6781 caaaaaaata gaacaagact acatgcaaca gttgcgcaaa ataatcaacc atttaccagc
     6841 gattattcaa aaaacggaag aattttttga tggatatcaa agtttatttc gtttagcaca
     6901 gcgtttcgtc accattggat atggtccaaa ctggggaaca gctaaagaag cagagacgaa
     6961 attgactgaa acaatccgcg ttccgtcaca aggatttgag ttagaagctt atatgcacgg
     7021 cccatacctg gaggcagatg cttcgcattt gctattcttt attgaagggg aaagtgtaaa
     7081 taaggaacgt tcgcaaaagt tgcaaagata tatgagtcgg tacgttggag agactctcac
     7141 cattaccaca aaaaaagcaa gaaacgagaa aacacttgga ttagcaatag aatgtgatga
     7201 atatctgtct gtattagcgc ttgtcgttcc gtttcaacta ttcgcttata aaaccgcagt
     7261 agctaaaggt attgacttga acaaaaagat ttttgaagac tttgatacag tcttgaaaag
     7321 taaattataa gaggtggaaa tcatgctgaa attcaatgaa gaagaacaaa tcaaagcaat
     7381 aaaaggcgca ctagctttac gtccgcaagt agaagaaatc atcgataaac tttatgcgga
     7441 aaaatttgac gctgtctatt atctaggaat cggtggaacg tatgcttcct cgatgcaagc
     7501 tgtcacttat atgaatggga aaagcaactt gcctgtcttt gtacagcatg ctgcagaata
     7561 ttacactact ggaaacaaaa gattaacaaa agattctatc gttattttgt cctctgttac
     7621 cggtacaact caagaagtag tgaaagcagt agaacaaatc aagaaagtag gagcgacact
     7681 gattggattt atcgataaag cgaacagtaa gttgtctcag ctatgcgatt ttgtggtcac
     7741 ttatccagct cctggaacag aacaaatcaa attttttatg gcagcagatc gattgatgta
     7801 tttgaatgga gaattcgaag cttattcaga atactatgaa cagctcgaac gttatttacc
     7861 aacagggtta gtggaagcag agaaaaaagc agatgcattt ggcttatcat ttgcagaaaa
     7921 acatcgacgt gatagtatgc attattttat tggagcaggg aatcaatggg gagctgttta
     7981 ttcatatgcc atgtgttact gggaagaaca aagctggctt ccatcgaaat ctatccatgc
     8041 tgccgagttt cttcacggga cgttagagat cgtagaagaa acaaccccag tcacattatt
     8101 tttaggcgaa gatgaacaga gagtgttatc tgaacgtgtg gctaaacttt tgccaaaaat
     8161 ttgcagcaat tatacattga tagacacaaa agactatcca gtagaaggta tcagtgaaaa
     8221 atatcgcgga cgtgttttgt ctttcttatt gatgcatgta gtgacacaac gcatcgatgc
     8281 tcatgtggag cagttgaact gccatccatt agagatacgc cgctactatc gtcagtttga
     8341 ttattaggat agactggata aaaagaatat aaaaaataaa gagagcagcg ataactgctc
     8401 cctttatttt tttaaaatat tggcatcaat tacgttataa aacacatttt ttgcattatc
     8461 tacagttcaa cttataatct gtttaatggg acatgtgggt gccaaccatt ttttgttatg
     8521 caatagtact atttagttgt tgcatggatc cgtagtaaaa gtccaagtac aacgagttgc
     8581 gccagtttac atagcgtttt gtatccagaa tgttgactaa aacaaaagtt cctatgtcaa
     8641 ccgtcaacag agacaatctg tccgttgcag gacctgacag atttagaaat gttcaatctg
     8701 tctcttatgt attttaaatc aatactcact aggagaagtt tcctaacctc ctaatagtaa
     8761 tgctggtagt aacattgtca aaactgcttc ctcttaggaa caagcaaagc ataacgagtg
     8821 taaaaataaa atgtagacta ttgtaacata tcattgatta tttcaagtaa aaacgataaa
     8881 agaagtaaac aaacacttaa aaacaatgga aattagtccc aactttaaga aatgtatact
     8941 ataatggaaa ttatcaatta tttatttgga ggaatatcca tgaaacaaaa aatcgcagtt
     9001 cttggtcctg gatcttgggg cactgcttta gcacaaacat tggcagaaaa cgggcatgat
     9061 gtccgtattt ggggaaatgt acctgaacag attgatgaaa tcaataagta tcatacaaat
     9121 cagcattttt tacctgattt gacgatccca gaatcgatta tcggatataa agaattggca
     9181 gaagcagtgg ataacgcaga tgctatttta tttgttgttc caacaaaagc gattcgttca
     9241 gtcgcacagg aacttattgg taaaatgaat actaagccaa tcattataca tgcaagtaaa
     9301 ggactagaac aagatacgca taaacgaatc tcagaagttt tggctgaaga aattccagaa
     9361 gaaaaaagac aggcaattgt tgtattatct ggtcctagcc atgctgagga agtggcagta
     9421 catgatatca caacaattac agctgcaagt attgatcaaa aagcagcagc ctatgtacaa
     9481 aaactgttca tgaatgatta tttcaggatt tatacaaata atgatgtgat tggcgtagaa
     9541 actggtgcag cactgaaaaa tatcattgca attggtgccg gcgctatcca tggattagga
     9601 ttcggagatg atgcaaaagc agcaatcatg actcgaggat tggcagaaat cagccgtctt
     9661 ggtgtcgcga tgggtgccaa tcctctgaca tttatcggtt tgagtggtgt gggggacttg
     9721 atcgttactt gtacaagtgt tcattctcgc aattggcgtg ccggtaactt gttaggacag
     9781 ggacataagc tggaagaagt tctagaaaac atgggaatgg tcgttgaggg tgtggcaacg
     9841 acaaaagcag cagtagagct agctcaacag ctaggtgttg agatgccaat tactcaaaca
     9901 atctataatg ttttgtataa tggagaagat atcaaaaaag cagcaaaaga aatcatgtta
     9961 cgtgacggaa aaatggagaa tgaattttct cttcgttaaa tagatgatca atagttaatc
    10021 gt
//
LOCUS       DADVXM010000084         9737 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.089, whole genome shotgun sequence.
ACCESSION   DADVXM010000084 DADVXM010000000
VERSION     DADVXM010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9737
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.089"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            902..1075
                     /locus_tag="KB927_002260"
     CDS             902..1075
                     /locus_tag="KB927_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841158.1"
                     /translation="MLKKTVLVLGSISLGILGFSPMLLSVIGKNNSNRELKLNSNYYN
                     SPNEELFVKQTDK"
     gene            1479..2633
                     /locus_tag="KB927_002261"
     CDS             1479..2633
                     /locus_tag="KB927_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBB6841159.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAIKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVHATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            2627..3049
                     /locus_tag="KB927_002262"
     CDS             2627..3049
                     /locus_tag="KB927_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841160.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            3351..3731
                     /locus_tag="KB927_002263"
     CDS             3351..3731
                     /locus_tag="KB927_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBB6841161.1"
                     /translation="MSEQNQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            3713..4627
                     /locus_tag="KB927_002264"
     CDS             3713..4627
                     /locus_tag="KB927_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBB6841162.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            4867..5556
                     /locus_tag="KB927_002265"
     CDS             4867..5556
                     /locus_tag="KB927_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841163.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GCIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQVLAQKIEKFTA
                     CYEDMNDIFVKQEKRLTDKNMETLTRLYRNLPEEQQKEYQEKYEQVKKDVQYVKDTKV
                     EEACSDLFGDTIPFSTSEQERKERQQSVTYERYEILLQQAINIQNLTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(5676..5762)
                     /locus_tag="KB927_002266"
     CDS             complement(5676..5762)
                     /locus_tag="KB927_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBB6841164.1"
                     /translation="MFELFICPLLVGVCISVFSYWLNNRNKK"
     gene            6408..7340
                     /locus_tag="KB927_002267"
     CDS             6408..7340
                     /locus_tag="KB927_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBB6841165.1"
                     /translation="MANEIVKYEPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFSQLKDLSAYKQTAGEVFIKDLARTYDHLMDLRFGRKSNGGLTIERFTMFTDFEIH
                     GEVDNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKQEDLRIKLFNIEHNGELTQKEKWRAKDRILNLPLGTHEAD
                     FKKQQQTEKEEAEKQSISNELKQDLLENLQNLFD"
     gene            7357..7827
                     /locus_tag="KB927_002268"
     CDS             7357..7827
                     /locus_tag="KB927_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBB6841166.1"
                     /translation="MIDKTIKELAEEFHVSKQAIRKRLSADFRENYVQTVTRNGVKTL
                     VVSYKGYLLLKQHFLGSNTTGNQVETVASNDENSIIVFLHEQLQEKDTQIKQMQKLLD
                     QQQQLTLQANQQIEKLQEQLQLAYTEEPEEEELTSVNKENNNAITTEKKWWKFW"
     gene            7911..8215
                     /locus_tag="KB927_002269"
                     /pseudo
     CDS             7911..8215
                     /locus_tag="KB927_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302541.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            8490..9671
                     /locus_tag="KB927_002270"
     CDS             8490..9671
                     /locus_tag="KB927_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6841167.1"
                     /translation="MKNNRIYKNQLNYGLLLPVFLLCIIGLLSLYVALYHDSYTNSKI
                     TKELIKQVLWYSIGFTSAITIYFFNPKILWKLTPIFYGLCIIMLLLLLKFYNPQLAVL
                     TGAKNWFYIAGFSFQPTELVKIGYTLMLAKITVNYQQKSITSNTKDDWIYLLKTFIAT
                     LPIGILLFFQNDLGTMLVFIVIYIFILFTSNINIKIIAPIIAIGVVLSLIFLYLVISD
                     TGRDFLLKIGFHDYQFKRIDSWLNPFLDPNGSSYQLANSLIAIGSGGLLGTGFNVSNI
                     HVPVRESDMIFSVIGENFGFIGSCLVIFLYFYLIYQMYKTCFKSNNLFFTYIGIGIVA
                     MIFFHVFENIGASIGLLPLTGIPLPYISQGGSAILSNFLGLGFMLCCSRYTNEKKGTQ
                     K"
BASE COUNT         3617 a         1549 c         1600 g         2971 t
ORIGIN      
        1 ttagtaaata ttagaggtaa acaaactatg cgtacttgtt accttatgag ttggaatgct
       61 agtagtagaa cagccaaata ttattactac atttagtaaa aacaaaacat tctttctata
      121 caataaaata gcgtatagag aggatgtttt taatttgaaa aggagtggtt atctttatga
      181 aaaatagatc atttgctata ttagtattat ccgtaatttt attagatata ttgttaataa
      241 cattagcttt aaaaacttta aatttagtaa caagttttgt cattatacca gtaattatag
      301 gaatgtctat ttatttcatc aaaaaaaata aacaattttt ttgaatgaaa ttacgggcga
      361 aaataatcac tcaaaattat taataaaaac gaatcaacta ctttttctga agaaacatac
      421 aaccgtaaac aacaattgtt gtttacggtt gtaaattatc aaactatatg gtgacttgtt
      481 gcttaaaata ggttgaaatt tcgtttattt tttttgagaa attttaccca cgtactaccc
      541 atgtacctat ccacgtatta cccatgtacc cccccatgac aaatgggcgg aggggcttgc
      601 ggcgcttggt attaaaggca ttatccgcct cccaggtttc tgaccatttt ctctcataag
      661 tggggttttt accgcgttga gagaaaatgg tcagaaacct aaacgatcgg caaagaaaac
      721 ataccaagcg ccacaagcaa aaaaagttag agtaacttcc agaaaagaaa aatttttaga
      781 acaacttttg aaaatttgat tttgatttat atccgttcaa tttaaacatt tgataaactg
      841 aaggctagta tttaaaatgt gtatacaagt ggtagcgtta aaaaaagtgg aggtataacc
      901 tatgttaaaa aaaactgtgt tggtactggg ttctatttct ctaggaatat taggttttag
      961 ccccatgcta ttatccgtaa ttggaaaaaa caattccaac agagaactta aattaaattc
     1021 aaattattac aacagtccta acgaagaatt gtttgtaaaa caaacggata aataataaaa
     1081 aagactgctc tttcgagcag ccagttaaaa aataatgagt gtttattctt gaaaaagcac
     1141 gcgcttatga agcgctacca aaaatttacc atattttaca aaaaataaca agtcttaaaa
     1201 aaatgacaga taaaaatgca caaagaatta gatatagata accgcgaaaa atcaagcttt
     1261 agaaagttgc ttttagctag accaattaaa aatcacaaag tgagcgtctc tatccattgg
     1321 tagaggggct acttggcata ctgtacatta tgttaactaa cgctataaat aacgattatg
     1381 ttcccaaaac aatattttat gaactataac aaaaatttgt tatcgcatat tgtatatttt
     1441 aattataggt gtataccact taaatttaac acaaaggcgt gattattttg aaacccaaaa
     1501 agaaaattta tctaggtctc ctcttttcct tgatgattgg aatttttagt ataggaatta
     1561 caaataccta tgcttcagaa aattctaatt tcaatatcaa ctcccaacca attgaagaac
     1621 aagcaattaa ttttgcgaaa actgattttg aacactccat aacttcaatt cttttaatgg
     1681 aaaataacac cgaaactgat attaactata ctcttggttc gccatttaaa atgctcgatg
     1741 gagaaaatac ggcaaatagt tctattttct ttccagtatt ttcagacgct gataatacga
     1801 ttaaatatat ttataccgtc aaaaaaaata caaatggaga atattcagga agtatttcac
     1861 aatttttagc aaaagaactt caaaatctag tagatagtaa tataacagat acaaccttat
     1921 tttttcaaga taatagcatt tattattccg ataatggaca aattaaacta ctttggaaat
     1981 cacctttaag tacagaaaaa aatggtgttt cttcctttac agaaaaaaat gatcttatat
     2041 ccgtaaatat aaaaaataaa attaaaaatt tctctaaaaa acaaaatttt cctgcgatta
     2101 aacgtgtaaa aagtgtctcc tccggagata actttattat gattaattgg cgtatagcag
     2161 aaacccaaac aagttttccg tggtgtgctg cttacgtaga agctgctatc ttatgtaaca
     2221 aaacagatgt acatgctact tcagctagag ccattatgca ttatacctat cctaatttaa
     2281 acaacagtca aattgaatca aaaagtctta atcaagatca aataataaaa tatgcaaatt
     2341 actgtggtgt ttatcctaaa aaagtagcac gaatactaaa cctttcagag gtccaaacac
     2401 aactaagaaa aggaaatgcc atttatatgg gaactgctgg ttatggaaat tatagtaaca
     2461 gccgtcatgc acttgcatta tttgggtggg tcaatcaagg tggttatcaa acttactatg
     2521 tgtggaatcc ttggtataac tacccaactg taataagtgc aaatgcagga ccagttacaa
     2581 ttcctgtacc tggaggtggt tttacttggg acaataccat tacaaattgg taaataaacc
     2641 cattgcttta gttatgggtc tagtgttagt tcttttctta actagttgtt caaaaaaaca
     2701 agaaatacaa aagactgatc tgattccttt tctaggaact tggcaaacta aagatcattc
     2761 agaacgtcta gtaatcacta atttaaatac ttcaaaaaat atagaacaat ataccatctt
     2821 agtaaaagag aacaatcata aaattcaaat cattgataaa aatttaaata taaatgaaca
     2881 agttttcatt tacaaagcaa caaataattt actaacactg cgctctaata aaaaacaatt
     2941 agattacact tttagtttgg attctccaaa aaagctcgta tttattttga caacgaatga
     3001 tgggacagaa gggacagcta aaccaattga attttttaaa gctgattgat gaatagttgt
     3061 ttgatattac aaaacaataa tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg
     3121 gctagcattt gctagccttt tttgtattgt ggagcgtggg ttttgagggg gattcaaggg
     3181 ggagcttgcg cccctttgaa aagcggttat ttgcaccaaa tacgtaggta tttggctagc
     3241 aaatatagag cttgccaaac ccttttagtg agctttactc attgtacctt tttaggtaca
     3301 atggtattgc gaacgatacg tccgtaggac gtactgaaag ggtgggactt atgagcgaac
     3361 aaaatcaaaa tttggctagc gatcattcta aaaaatatac ctatcgatcc gagccaaaac
     3421 aaatcagttt tcgagtgagc gaatctgaat ttgcaaagct gaagcagtca gctgaagctt
     3481 tgcaaatgag tgtgccggct ttcgtaaaag ccaaggcaca aaacgcgcgt ctggtgacac
     3541 cgaaagtggc gccagacatt gcccaggcaa tcgcgcgcga tttagccaaa gctggaggga
     3601 atatcaatca aattgctaag tggtgtaata cacaccaaca cgacgttgct cctggagacg
     3661 cccaacgctt atccgaaaac ctaaaaatca tgcaaaagga gctacaaaag atatggcaac
     3721 agttaaagta agccgaacca cttcttgtag tcgtgcaatt aattacgctg aaccacgagc
     3781 aaccattaaa acaggaataa actgtgacgt cgattatgcc aaaagtgaaa tgaaacaaat
     3841 tcgcatgctg tatggaaaag acgaccgtgt acaggcacac ttattgattc aatcttttcg
     3901 accaggagaa attaccgctg aaaaagctaa tcaactaggg gcagagtatg caaaaaaaat
     3961 agcccccgat caccaaatag ctatttacac acatacagac aaagaccata ttcataatca
     4021 cattgtcatt aactccgtta atctggagac tggaaaaaaa tttcaagctc atggtcaagc
     4081 atttctaaac aaatgttatg acctaaatga cgagatttgt cttgcacata acttaccaat
     4141 cactgagcga ggaaagaaac cagaaaaacg aaccatgtct gaaataaaat taaaagaaaa
     4201 aaatgaacct gtttggaaag acgaaattcg gattgcgatc gatcaaacaa tgaaaaacaa
     4261 aaaaaccaga acctatgacc aattttgtaa ttccctcaaa acattgggga ttcattgctt
     4321 caatcgcggg aaaaatttca cttacgaatt gatccacaaa aagaaaaaag tacgatccaa
     4381 cagactagga aaggactacg aaaaggagac gattttacat gagctggaca gacgagaacg
     4441 aacctataac caacagcgaa ccaacgagct acgaagagct cgagctagca ttcgcgaaac
     4501 tgcagaagaa gtacgaagag aacaacgaac tcttacgcct gaacaaccgg aaattagacc
     4561 ggctcgaaga aaccatgaac aacacgttga aagaggaaca gaccaccaac aagaattatc
     4621 gctctaaatc gttaaaagac atagaaaacg aaataaagaa acaacgtgct tttctcgttc
     4681 cttatacgca agaaaggata caaactacga ttgatttaca agttaaaaaa ctccatcaag
     4741 agctattaga ccagcgaaat aaggaacaga aaaaggtgct tattcaacga tcattggatt
     4801 ttcttgcccc cttatgttgc ttagtcctga cactgttcgc attttggtta gtatggggag
     4861 gctaaaatgg cattttattt accctatcta ctcatttttg ttagtatttc aggaagtatt
     4921 tggctcatct ataaaatttt tcaaacaaga tattcattaa aaggctctaa aattcgattt
     4981 aagcgatttt tctttcttgg ctgtatattt tccttgataa tcgtttcaag cggcttattc
     5041 ggcgttttag agggaaataa gcgcgtttct agaagtattt tattaggaaa tgtcactcaa
     5101 aagtatgaat cagcgcgtga taaaaagaaa aaagagcaag tattagcaca aaaaatagaa
     5161 aaatttaccg cttgttatga ggacatgaat gatatttttg tgaagcaaga aaagcgtttg
     5221 acggataaaa atatggaaac actcactcga ctttatcgga atttgccaga agaacagcaa
     5281 aaagagtacc aagaaaaata tgaacaagta aaaaaagacg tgcaatatgt gaaagatacg
     5341 aaagtggaag aagcttgtag tgatttattt ggagatacaa ttcctttttc aactagcgaa
     5401 caagaacgaa aagaacgaca acaatcagtc acatatgaac gctatgaaat cttgcttcaa
     5461 caagcaatta acatacaaaa tctgactaaa aaagaaacag ctttaaatta tttaaaaagc
     5521 gtcaaggaat ggttagatca gcaacagcaa aattgaattt gattgaaatt catgttaaac
     5581 taaacatgca aatgttcaaa cattagatac acgaaagccc cagagaggtc ggattctctg
     5641 gggctttttt taggttgatg tcgcctttac tgattttact tcttgtttcg gttattcaac
     5701 caataactga atacagagat acaaactcct acaagaaggg ggcaaataaa cagttcaaac
     5761 atcagataca cctccttcca gtcgcaagac tgtcggatag gcgacaagtt attataccct
     5821 acaaaattaa atctgtgtgg caattttaag tatctcttat ttccgggttg ttagggcttg
     5881 ccctgaccgc ctgtagggcg ctttaaatgc cagataaagg tttttatact aagactgtct
     5941 taaaacggct tagacaagct cttagagcct caaccctcct ttttgaacaa tggttttagc
     6001 aaaggagctg gaggcgactg cgcaggtata atgtgagagc gtagcgatca cacctttttg
     6061 gcgaccgtag ggagcgaggt tttgaattag cagtttagaa aagttcgcga acctgtttaa
     6121 agaaaaaata attgtttttt taggtgggaa attttgtctc cctcttttat aatctttttt
     6181 taaacctctt tttaaacctc tttaccgtcg gctgtgtcct tactccccca agggatacaa
     6241 aattttatag gcatgaaatt atctgtttat aggcatgaaa ttatctgttt ataggcatga
     6301 aattatctgt ttataggcat gaaattatct gttttaggta ttgtttttag acataatatg
     6361 tcctaaaatg atgtcaataa aatcatttag actggagtaa caactaaatg gcaaatgaaa
     6421 tcgtaaagta tgaaccagaa ttaaatacca ttcctttaag aaaatttacc ccaatagaaa
     6481 tgaacttgtt tttttctatt gtctctagaa tgcgcgataa aggtaatcaa aaaatacgct
     6541 tttatttcag ccaacttaaa gatttaagtg cgtataagca gactgcagga gaagtcttta
     6601 taaaagattt ggcaagaaca tacgatcatt tgatggattt acgtttcgga agaaaaagca
     6661 atggtggatt aacaatagaa cgatttacaa tgtttactga ttttgaaatt catggagaag
     6721 tcgataaccc ttatgtagat ataaaagtcc acgaaaaagc tttgccttta cttaataatc
     6781 tagaaagctg ggtacgtttc tctttaacag aatttcgaga tttaaatagc agttatgcta
     6841 aaacaatgtt tagattgcta aaacaatacc gaactcaagg atgggctgaa ttttctaagg
     6901 aagatttttt agagctatta gatattccta aaagctatag acaaacaaat ataaatcagt
     6961 ttgtactcaa accaataaaa gaagaactaa ctccactatt taaaggatta actattcgta
     7021 aaaaatatgg taaaggtcga ggtaaacctg ttattggtta tcgttttact tggaaagctg
     7081 aaatcaacca tgctgacgat ttttcaaaag ggaagcaaga agatttacgt ataaaattat
     7141 ttaatattga acacaatgga gaattaacac aaaaagaaaa atggcgtgct aaagatcgaa
     7201 tactaaatct tccgttaggt actcatgaag ctgattttaa aaaacaacaa caaaccgaaa
     7261 aagaagaagc ggaaaaacaa tcaatctcaa atgagcttaa acaagattta ttagaaaact
     7321 tacaaaactt attcgattga agcataagga gtatttatga tagataaaac gatcaaagaa
     7381 ctcgcggaag aatttcatgt ttcaaaacaa gcaattagga aaaggctatc agctgatttt
     7441 agagaaaact atgtgcaaac tgttactagg aacggagtga aaaccttagt tgtcagctac
     7501 aaaggatatt tgcttttaaa acaacatttt ttaggtagta acaccactgg taaccaagta
     7561 gaaaccgttg ctagtaacga tgaaaactcg attattgttt ttttacatga acagctccaa
     7621 gaaaaagata ctcaaataaa acaaatgcaa aagttactcg accagcaaca acaactcacc
     7681 ttgcaggcaa atcaacagat cgaaaaactg caagaacagt tacaattagc ttatacggaa
     7741 gaacctgaag aagaggaatt aacttctgtc aataaagaaa acaacaatgc aataacaaca
     7801 gaaaaaaagt ggtggaaatt ttggtaacaa ttaccaactt tccataaaga agaaatcaat
     7861 ttctatagac tctatctttc taagaataaa aaatatgttt aggtgatcaa atgactataa
     7921 gtaaagtaat caaacaaaaa agaatagaaa aacaactaac tcaagaagat ttagctgaaa
     7981 tgcttttagt atctaaaaaa accatttcta attgggaaaa tggtcgaaca ataccagata
     8041 cagaaaattt aattcagttt gctaagttat ttgatttatc actagacaat attttgttag
     8101 gagaagaaaa aattatggta aaaaatcata caaaaacact aatactatta tttcattttg
     8161 taattttttt aagtttagtt ttcaccttaa ttcagtccgg attcttttat tttagccatt
     8221 caattgccac ttggttatta atattttttc taagtttact attaataatt aatactttaa
     8281 ttattatctt taataaacat agaaacttat ttcttcacag catatttcca attgttttat
     8341 taatttttct atactttata taaaaagata gaactattta gtaagataaa aaagtagcta
     8401 attgtaattt tcgtctaaaa ctcaaaacta gtaaaaataa ctttattgtg ttatttttat
     8461 ttataaatta tgaaaaagga cctttcgaaa tgaaaaataa tagaatctac aaaaatcagt
     8521 tgaattatgg gcttttattg ccagtttttc tgctatgtat cattggatta ctttctttat
     8581 atgttgcttt atatcacgac tcttacacta attcaaaaat cacaaaagaa ttaattaaac
     8641 aagtattgtg gtatagtatt gggttcactt cagcaataac tatttatttt tttaatccta
     8701 aaattttgtg gaaattaact cctatatttt acggattatg catcataatg ttattacttc
     8761 tcttgaaatt ctataatcca caattagcag tcttaactgg agcaaaaaat tggttttata
     8821 ttgctggttt ttcgtttcaa cctactgagt tagtcaaaat aggatacacc cttatgctag
     8881 ctaaaataac cgtcaattat cagcaaaaat ctattactag taatacgaaa gatgattgga
     8941 tttatttact taaaactttt attgctactc ttccaatagg aatattatta ttttttcaga
     9001 acgatctagg aacaatgtta gtcttcattg ttatttatat ttttattttg tttacgtcta
     9061 acataaatat aaaaataatt gccccaataa tcgccattgg tgttgtttta tccttaatat
     9121 ttttatattt ggttatatca gatacaggaa gagatttctt attaaaaata ggatttcacg
     9181 actatcagtt taaaagaata gactcatggt tgaatccatt tttagatcca aatggatcta
     9241 gctatcagtt agcaaatagt ttaattgcta ttggctctgg cggactttta ggtactggtt
     9301 ttaatgtatc aaacattcac gttcctgtta gagaatccga tatgatattt tctgtaattg
     9361 gagaaaattt tggctttata ggaagttgtc ttgtaatatt cctatacttt tatttaattt
     9421 atcaaatgta taaaacatgt tttaaaagca ataacttatt tttcacctat atcggtatag
     9481 gcattgttgc aatgattttt tttcatgttt ttgaaaatat aggtgcaagt atcggattac
     9541 tacctctaac tggtattcca ctcccctata ttagtcaagg tggttctgcc attcttagta
     9601 attttttggg gttgggattt atgttgtgtt gtagtagata tactaacgaa aaaaaaggaa
     9661 cacaaaaatg aattcaaaat aacactttat gaatagaatg tctatttcaa taaaaattat
     9721 gataccttaa agttaat
//
LOCUS       DADVXM010000085         9657 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.090, whole genome shotgun sequence.
ACCESSION   DADVXM010000085 DADVXM010000000
VERSION     DADVXM010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9657
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.090"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            185..1183
                     /locus_tag="KB927_002271"
     CDS             185..1183
                     /locus_tag="KB927_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6841168.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="KB927_002272"
     CDS             1295..1804
                     /locus_tag="KB927_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBB6841169.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="KB927_002273"
     CDS             complement(1834..2493)
                     /locus_tag="KB927_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBB6841170.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="KB927_002274"
     CDS             complement(2495..3259)
                     /locus_tag="KB927_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBB6841171.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="KB927_002275"
     CDS             complement(3267..3944)
                     /locus_tag="KB927_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBB6841172.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="KB927_002276"
     CDS             complement(3981..5366)
                     /locus_tag="KB927_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6841173.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="KB927_002277"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KB927_002277"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="KB927_002278"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="KB927_002278"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBB6841174.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="KB927_002279"
     CDS             6305..7162
                     /locus_tag="KB927_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841175.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="KB927_002280"
     CDS             complement(7243..7578)
                     /locus_tag="KB927_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841176.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="KB927_002281"
     CDS             complement(7645..9015)
                     /locus_tag="KB927_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBB6841177.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="KB927_002282"
     CDS             complement(9093..9629)
                     /locus_tag="KB927_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6841178.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
BASE COUNT         2825 a         1996 c         1619 g         3217 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcactatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatgctactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag taaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctaccc
//
LOCUS       DADVXM010000086         9371 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.091, whole genome shotgun sequence.
ACCESSION   DADVXM010000086 DADVXM010000000
VERSION     DADVXM010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.091"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            236..1042
                     /locus_tag="KB927_002283"
     CDS             236..1042
                     /locus_tag="KB927_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6841179.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            1054..2274
                     /locus_tag="KB927_002284"
     CDS             1054..2274
                     /locus_tag="KB927_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6841180.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     NKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            2264..3850
                     /locus_tag="KB927_002285"
     CDS             2264..3850
                     /locus_tag="KB927_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6841181.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVVQTSIAQPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSEAT
                     ERMVFRFAQQPSFIEFSAEAAGEKLIFIDSNAVVKTVNDCYLFDGKEIPEFALTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENQHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKKTSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSRDEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            3889..6027
                     /locus_tag="KB927_002286"
     CDS             3889..6027
                     /locus_tag="KB927_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6841182.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKIRLSGKMRGKAILDFQTAKHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKTIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNIHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKKLGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSVIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            6315..7706
                     /locus_tag="KB927_002287"
     CDS             6315..7706
                     /locus_tag="KB927_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBB6841183.1"
                     /translation="MNKNGEWNAARRIFIIIMDVLVLNVSIYLSFLLKFQGEVPARNL
                     ETFQHSAVFISIIFIALNILLGAYVFYSRVISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVIVLSFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVVIDKYYENTKKLIDDIDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFKIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSVTAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENIRS
                     LAEIDFSQEKIYR"
     gene            7765..8574
                     /locus_tag="KB927_002288"
     CDS             7765..8574
                     /locus_tag="KB927_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6841184.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFNHMTVMFD
                     KNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYARRGGSKYL
                     LPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN"
     gene            8546..>9371
                     /locus_tag="KB927_002289"
     CDS             8546..>9371
                     /locus_tag="KB927_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6841185.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLKRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNCGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNYPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMVPMYEAFRAASKIDILPFSGIFYYQNNDSI
                     VYQSFNSKQYDNILQRKILVDEVKKDYPRLINLANARLVDGYLSTGFKITGKNQNQK"
BASE COUNT         3222 a         1440 c         1895 g         2814 t
ORIGIN      
        1 aaacgaagaa aaagtgttag tagaaaatcg ccttcgattt tccaccaaca caaaatatta
       61 tagaacccct tttttggttt attgcaattg tctagcatct tctgtaaaat agaaacgtta
      121 gagaaaatct tgtatcatag aaaattaaga aagaaataag aacgcagctc ggtaccaaaa
      181 atatggtaaa atggcacttg actgtaattc actgaaatcg cttggaggaa cacaaatgtt
      241 taaagatttg tatttattta tgaaagacat ttatcagaat agaaaattac tgctacagtt
      301 ttcgatcaat gacttcaaat caagatatgc aggatcgttt ttaggaatct tatgggcgtt
      361 tatcaatccg ctatttactg tattgattta ttggctggta tttggtgttg gactgaaagc
      421 acaaatgatc gatgcaaaat acccatttat cgtatattta gttaccggga tgattccctg
      481 gttcttcttc tcagatgcat ttgcatcaac tacggttgtt tttcgggaat atacttattt
      541 agtaaagaaa gtcgtattca atattcgtat cttgcccacg acgaaaatcc tatccaatct
      601 gtacacccat ttattcttca ttctgattgg catagctgtc gcgcttataa atggtatata
      661 tccttcagca atgtctttac agctgattta ttatttattt tgcatgtgtg ctttcttgac
      721 aggattgact tggctgacgg catcgatcca accattttta cctgatatca tgcaattaat
      781 tacgatcgtg ctgcagttga tcatgtggac attaccgata ttatggagcc ctaatcagtt
      841 tgattcaggt cttgtaagca tattgaaatt aaatccgctg tactatgttg ttcaaggtta
      901 tcgtgagtca tttttaagtg aagcttggtt ctgggagcat ggaacatata ctttgtattt
      961 ctgggttttc acgttagtaa tgttcgtaat cggctctgca gtgttccgta gattgaaacc
     1021 acatttttca gatgtgctgt aaggagaata gctatgacag aatatgcaat tagactaaaa
     1081 gatatcacaa aatcttataa tatgtacgca aaaccttcgg atcgatttcg tgaagccctc
     1141 aatcctttta agaaatccta tcatgatgta ttttatgcgt tgaaaaacgt gaatgtagaa
     1201 ataaaaaaag gtgagatgat cggtttcgtg ggagaaaacg gatcgggaaa atctacaatg
     1261 ttgaaaatca ttacgggagt actgacacca acatccggca cgatggaaat cgaaggaaaa
     1321 atctcagctt tgctagaact aggatcagga ttcaatcctg agtattctgg ctatgaaaat
     1381 atctatttaa atggaatggt tctaggattt tcaagagaag aagtcgatga aatggtcgat
     1441 gatatcattg aatttgctga tattggcgac catatttatc aacctgtaaa aacctattca
     1501 agtgggatgt tcgttcgtct agcttttgct gtagcgatca atgtgaatcc tgatattttg
     1561 attgtggatg aagcattggc agtaggagat cttgaattcc aactgaaatg tatggaaaaa
     1621 tttacagaaa ttaagaactc gggaaaaacg attttattcg tttctcatga tattagttcg
     1681 attcgccgtt tttgtgatcg ttcctattgg ttgaaaaatg gagaagttgt cgaatatggt
     1741 gatacgatgg aagtaacgac gaattacgaa aactttttga agaaaaaatc agttaaaaca
     1801 gtagatcgaa ataaaaacca agtagaacgc ttcgcagctc cagatatcgt agacgtgacg
     1861 aaagccgaat tgttggataa aaataaaaat ccagtggata tgctggaaca aggagaaaaa
     1921 ctatacgtta aagtaaccta tgaagtaaaa gacgatacaa tcaaaaatcc agttttagga
     1981 attgctctgc gtacagtcga caatttttat gtgtgcggac tcaatactct actagatggt
     2041 atcaagatcc cttggaaaaa aggtgagaat atcttttatc tggagtatga aaagttaggt
     2101 ttgttagctg gtgaatatta ttttgacgtt gcggtctttg aagaaaatgc aacggttcct
     2161 ttggtataca agacaaaata catgaacttg tttgtcagcg gttcttatat cggagaaggc
     2221 atcgtggtct tagaccataa atgggaagaa gggactcata gcaatgaaat atgattttga
     2281 aatggaccta gatgaacaaa gcagtgtggg aaaaattgcc gcacagatca aaccaggaag
     2341 taaagtttta gagtttggtc ccggaaacgg tcgattaacg aaacatttga tcggagcaaa
     2401 acaatgtgaa gtgagcattg ttgagctaga taaggaatta ttcgattttg tcagcgaatt
     2461 tgcccaagat ggattttatg gagatatcga aagttttgaa tgggcaaact attatgctgg
     2521 acagacattt gattacgtct tgtttgcgga tgttttagaa catttagtag atcctggaaa
     2581 aacattgaag aaagtcagag aatttttgaa tgaagaagga gagatcctga ttacattccc
     2641 taacttagca cataattctg tcatgatcga tttgttcaat aatcaattgc cttgggcttc
     2701 ttatggtctc ctagatgaaa cccataattc tttttatact catgatggtt tccaaaaagt
     2761 ttttgaaaaa gccggattat tcattaatat tgaagattac ttgtacttgg ctgtaggaga
     2821 tacagaatta aaatcaactt atgaagagtt gccggaagct gtacgctatg atttcaaaat
     2881 gcgaccattt ggtgaagtct accaatactt tttctcattg atgaaacatc cagtagtaca
     2941 aacttccatt gcacagccac aaaactctaa ttatgtaaaa gtactagaag taacccagca
     3001 aacgaaacaa gatgaaacaa tccaacaaat accattcaat aatttcacag gggaaaatga
     3061 gacactaagt ttccccgtgt cagaagcaac agaaagaatg gtgtttcgct tcgcacagca
     3121 acctagcttt atcgaattca gtgcagaagc tgctggagaa aaactcatat ttatcgattc
     3181 aaatgctgta gtcaaaacag taaatgattg ttatttgttt gatgggaaag aaataccaga
     3241 gttcgctcta acggatattt ctgggaaaga agtgactatc cattgtcact atcgctttat
     3301 cggggaattg acaccaacaa tgaaagaatt gctggaaaca attcgtccta tggctgaagt
     3361 cacaaagcag ctttctgaga aaaatgatga attagaaaga gaaaatcagc atcttcttga
     3421 ggaaaataca agactagacc atacgttaaa aacaaccaca aatcgctatt gcacattgtt
     3481 ggaaagtgat gaatggacga tcaaacatag actaggacga cgtaagaaaa aaacatcgaa
     3541 aaaaatacaa gaaaaagagc tttctatatg tattgatgag aaaatatggg atgcagaaac
     3601 aaaaatatta aaaatcatcg gatggggaat cgctaattcg gatcgccagc cattgtccta
     3661 taagttatca gctgaccaat cgccattttt cgaagcaatt cctgtttcac gagatgaagt
     3721 caatcaagca gaacagctcg caaaaggaac agaagcggga tttgaattac gaatcctttg
     3781 cgagcaagaa cgttcattct tagtggaagc agtagctcaa aatggtcaat catggatcat
     3841 tgaaatgtaa ataatgatta acttataaag ataaggagta aacgaatcgt gcaaaaaaaa
     3901 gaaattgccg tatttatcga tcaaatcact cgtgaacggg ccactggcga tttgcttatt
     3961 gtgggctggg caattgatga agtgaccaaa gaaatcccta cgataaaggt agaaaaagaa
     4021 aatgtgattg ctgaagcaac acatgtcgta agattggata tcaatcattt atataatctt
     4081 gatgttaaga cccaaagcgg ttttaagata cgtttatccg ggaaaatgag aggaaaagcg
     4141 atcttagatt ttcaaacggc aaaacatcaa aatggcatag ctgtgaaact aaatggtaaa
     4201 tacccttatg atgacggcat tgaatcttca tgggaaagaa aaaaaagatt actgaaaaaa
     4261 gggataaatt atgcaaggac tcatggcgta aaaaaaacaa tccgccgggt caaactggaa
     4321 ttgaaaccag gatcgatcga ctatgcagag tggatcagtc gtcacgagaa acctgatctg
     4381 aaagagcaaa ggaaagaagc acaagggttt gcataccgtc cattgatttc catacttatg
     4441 cctgtctata acgttgaaat caaatggctc gaaaaatgca ttgattcggt attggatcaa
     4501 acgtatgatc actgggaact atgtatcagt gatgatgctt ctactgatcc agctatccga
     4561 aagtgtctgg aatcctatca agcaaaggat gatagaatca aagttgtttt ccgacaagaa
     4621 aatggacata tcagtctggc aactaattct gcgttggaaa tggcagaagg agaatttata
     4681 gcgctcttag ataatgatga tgaattaccg ccatttgcat tatatgaagt ggcaaaagtg
     4741 ctaaacatac atccagaact ggatttgatc tacagtgacg aagataaaat cgatgcagat
     4801 ggcaatcgct ttgatccgca cttcaaagca gactggtctc ccgatacatt gatgggaaat
     4861 aattatatct ctcacttagg cgtatatcga acaagtattg tgaaaaagct tggcggtttc
     4921 cgtaaaggct acgaaggctc tcaagattat gatttggtcc ttcgtgtgac agaacaaatc
     4981 cctgcagatc atatttacca tattgaccga gtcttgtatc attggcggac gatcccagga
     5041 tcaaccgcaa gtaatggtga agccaaaagt tatatctatg attctggagt gaaagcattg
     5101 acagatgccc tgtctagaag gaatatcaaa ggaagcgtac gtcctggcag aatttctgga
     5161 ttttatgaga ttgcttatga cgtcttgcaa gaggatttgg tcagcgtgat cattccaacg
     5221 aagaatggct atgaagatct aaaaacttgt gtggattcgg ttatcgaaaa aacgtcttat
     5281 ccaaattatg aaatcattat tgcagataat ggaagtacag atcctaaaat gcaggaatta
     5341 tttgcagaat acaagcatca gctgaaagac cgatttatcg ttgaattaat tgacattcca
     5401 ttcaattatt cacgtatcaa caatctggca gcagaaaaag caaacggcaa atacttttta
     5461 ttcttgaata acgatacaga agtgattgaa cctgactgga tgacagcgat ggtttcttat
     5521 gcacagtttg atcgaatcgg ctgtgtagga gcaaaactgt tttatccaga tgatacaacg
     5581 cagcatgcag gagtattatt aggaatcggt ggtgttgcag gacatgcatt gaataactat
     5641 gatcgaacac attgtggtta tttcggccga ttggtcattg acgtcaatta cttagcagtc
     5701 actgcagctt gtatgatggt caaggcagct gacttcaatg ctgtcaatgg atttgatgaa
     5761 acattagaag tagcattcaa tgatgttgac ttgtgtttga aagtttatga actgggtcgt
     5821 tacaatgtct atgcacatca agcagaattg tatcatttcg aatctaaatc aagaggttat
     5881 gaagatacac cagaaaaaca aagacgtttt gccggggaaa taaaaaaaat gcaagataag
     5941 tggccttctt atattgctca tgacccattt tataacgata atctaactaa agaaggaatc
     6001 ggcgattttt cattgagacc tgattgatta aaagaactgt attttcattt ttattgatga
     6061 aaatacagtt tttttagtat atgaaaattg taacttgtga ccgaagagat gataggaaga
     6121 acacccattc agtaggaaga atgtgatacg atttttgtcc aactctctgt taggcagaaa
     6181 tatacatata aacatacaat agtcaccttt tctagtttct tttaatttat tttacaattt
     6241 ggttattcac taggttttta aactttgcta tggtaagatg atagaggcat tattttatgg
     6301 ttaggagtgt atatatgaat aaaaatgggg agtggaatgc ggcacgtagg atattcatta
     6361 tcatcatgga tgtacttgta ttgaatgtgt cgatctatct tagctttttg ctgaagttcc
     6421 aaggagaagt cccagcaaga aacttagaga cctttcagca ttcagcagtt tttatttcca
     6481 ttatctttat tgcgttgaat attttgttag gagcttatgt attctatagc cgagtgatca
     6541 gtgatatcgt cttcattact gttattggac aggtgctgat agcattgggg atcatggtag
     6601 ttacttttgc tggacgttgg tttgcatttc cgcgtggcgt catcgtgctc tcgtttatac
     6661 ttggcacgat attacttagc gtttatcgga tagttgttta taaactatac ttaagagtca
     6721 gtcgtgataa gaaagtcctt atcgtaggtt tggagaaaga tgtcgcacca gctatccaaa
     6781 actttcaatc taagaaaaac aacaaacata aagttgaagc agtagtgatc gacaagtatt
     6841 acgaaaacac aaaaaaattg attgatgata tcgatattgt ctacttggct tctaaaatcc
     6901 cagaagacga aaaaatcaat atttatcaat tagtaactaa aaaagagaag aagctatttt
     6961 taaatacaac ttttgaaaat ttaacgatga tcaatccgaa catcatgaat ttcgaagatg
     7021 aaagtatcat tgaagcttcc ggtttcaaaa ttcagccgga atatgaatta ttcaaacgtc
     7081 tttttgatat catcgtttcg cttattttac tgattcttgc ttcacctttt atgctaatca
     7141 cagcgatttt ggtaaaaaca acttcacctg gaccaattat ttataaacaa gtacgtatta
     7201 cgaaaaatca aaaggaattt tcaatctata aatttcgttc catgagtgta acagctgaag
     7261 caaaatcagg accggtcttg gcaaagagca atgatgcacg tgtgacacca gtaggcaaat
     7321 ttatccgtgc cgtacgtttt gacgaattac ctcaaatctt taatgtattg aaaggcgata
     7381 tgtcgatcgt cggaccacgt ccagaaagac catttttcgt tgatcagttc aatgaagaaa
     7441 atccttatta ttatttaaga cacaatgtac gtgcagggat taccggatat gcacaagtat
     7501 acggaaaata tgtatcagat tataatagta aactacgttt tgatttgttg tatatcaaaa
     7561 agtattcctt actattagat ttgaagattt tacttcaaac aatcaaaatc ttatttgata
     7621 agatgtcctc acaaggacta gatgaagatg aaaatatccg ttcgttagca gaaatcgact
     7681 tttcacaaga gaaaatttat cgctagatgg gaaaaatttt gagcaaagaa gtaggagaga
     7741 acattggaaa ataaaaatat aagtatgctg ctttctttat atgataaaga aaaaccagag
     7801 tatttaaagg aagcattaac tagtattttt gagcaaacag taatgccaaa agaaattgta
     7861 ttagtttatg acggccctat aaatgaaaaa cttcaagtag ttgtcactta tttccaacaa
     7921 aaagatcctc acttgtttac agttgtaaaa ttagaaaaaa atcaaggatt ggggattgct
     7981 ttagcaattg gattagaaca tacgaaaaat cgcttagtag ccagaatgga tacagatgat
     8041 atcatggaac cccaacgatt agaaaaacaa ttagagatct tccaaaaaga tccagaaata
     8101 gcgattgttg ggagtaatat tgaggaattt actggcacgc ttagcaatgt tatcggaaga
     8161 aggattgtac ctgaatataa tgatgaaatc cgtgtgtttt cgaaaagaag aaatcccttt
     8221 aatcatatga cagtcatgtt tgataaaaat gctattttag aagtgggaaa ctatcgccca
     8281 ttaattggat ttgaagatta ttatttgtgg gtaagactgt tgaaggcggg atataaaggg
     8341 tataatatcc aagagattct agtccatgct agagcaggtg ctgacatgta tgctagacgt
     8401 ggaggaagta aatatctttt accaggaatt aaaggccgat atcgcgtatg gaaagatggt
     8461 ctaggatcac taaaagattt tctgatagtt atttgcggac atcttgtaat tagtttatta
     8521 ccgaataaaa ttaggggaaa agtatatgaa tcaaaactta gaaaaacaaa ctaaactttc
     8581 tataatcata cctttttaca atgcaaaaaa tactttaaaa agagctgtag acagcgtctt
     8641 aacgcaaggt tatcccaata ttgaaatctt gttaattgat gatggatcta cagatggtag
     8701 tagtgacatt ggtgacgaaa ttgctaatct agagagtaaa gtagcatgtt atcacttgga
     8761 aaacgctggt ccatcagttg ctaggaattg tgggataaaa gaagcaactg gaaatttggt
     8821 aggattttta gatagtgacg attatttttt acctgattgt tttaataatg ttttgaaaga
     8881 ctaccatagg aattaccccg atatcattgc ttttggatta agtaaaggaa aaaatataga
     8941 aaatgcaaat ttatttgttc ccgaaaagaa gattggttgt tcaagtgaag aagcaattga
     9001 gcaaatgttt agaagtaagg cagtggattt ttacgtatgg aataaatttt ttaaaaggga
     9061 attattcaat catatagttt ttccagaaaa taaattatat gaggatatgg ttcctatgta
     9121 tgaagctttt agagcggcta gtaaaattga tattttgcca ttttcaggta ttttttatta
     9181 tcaaaataat gatagcatcg tttatcagtc ttttaattca aaacagtatg ataatatttt
     9241 gcaaagaaaa atattagttg atgaagtaaa gaaagattat cctcgactta ttaatttggc
     9301 caatgctcga ttagtagacg gatacctttc aacagggttt aaaattactg gcaagaatca
     9361 aaatcagaaa g
//
LOCUS       DADVXM010000087         9328 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.092, whole genome shotgun sequence.
ACCESSION   DADVXM010000087 DADVXM010000000
VERSION     DADVXM010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.092"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(59..727)
                     /locus_tag="KB927_002290"
     CDS             complement(59..727)
                     /locus_tag="KB927_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6841186.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            861..1148
                     /locus_tag="KB927_002291"
     CDS             861..1148
                     /locus_tag="KB927_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841187.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1564..3102
                     /locus_tag="KB927_002292"
     CDS             1564..3102
                     /locus_tag="KB927_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBB6841188.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3099..4064
                     /locus_tag="KB927_002293"
     CDS             3099..4064
                     /locus_tag="KB927_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6841189.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4051..5373
                     /locus_tag="KB927_002294"
     CDS             4051..5373
                     /locus_tag="KB927_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6841190.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5436..5540
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5614..6357
                     /locus_tag="KB927_002295"
     CDS             5614..6357
                     /locus_tag="KB927_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6841191.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAV
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6372..7364
                     /locus_tag="KB927_002296"
     CDS             6372..7364
                     /locus_tag="KB927_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6841192.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7376..8113
                     /locus_tag="KB927_002297"
     CDS             7376..8113
                     /locus_tag="KB927_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6841193.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8103..8825
                     /locus_tag="KB927_002298"
     CDS             8103..8825
                     /locus_tag="KB927_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBB6841194.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8909..>9328)
                     /locus_tag="KB927_002299"
     CDS             complement(8909..>9328)
                     /locus_tag="KB927_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBB6841195.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3056 a         1605 c         1968 g         2699 t
ORIGIN      
        1 cattttagtt tacataatga tatttctgta aattaaataa agtagtgaaa aataagaatc
       61 agtgctctaa ctgttcaaga ggatcaagtg gttcaaatgt ttctgtagtc tgttttgctt
      121 ccaattgggg caaaacagat ccaatttcca gatacttcac tttattcaat gtataagata
      181 gaatagaaca gctaagtaat gtatacagaa aatgtgtgag atccaaataa agcaaggaga
      241 caactaaaat accaaaagta atcaagaaaa gacttttgcc aatcttaata tgaaaatatt
      301 tttcaatggc ttgataaatg atatctgttc cgcctgtgct tccgccgaat cgaaagacga
      361 gaccgcaacc aatgccagaa agaatacctg tcatcaaact attgatcagt agactatcta
      421 cagcaaaatg tatatgaagg ctctcccata aatgtaaaaa gaaaactagc gcaaatgttc
      481 cgacgatcgt ccggagaaaa gcgtgttttc caaaaagaaa caatgagata agcaataaag
      541 gtaaattaaa aagcagtgaa gtgacagaag gagcgaatcc aaaaagatta tgcaaaagca
      601 aagcaatacc agtaacccca ccatctgcca gcttagatgg aatattgatt cctgtcacag
      661 ctaatccgta gattcctgcg cctaaaatga ttccgcacaa ttctgtaaat aaatttaatt
      721 ttttcatttc tagcctcttt tcttttgaaa attttcagca acttctttat tatactgact
      781 tatactctta cttcaagagg aaaatgaaaa aaaattattt ttggctgttt ctttttattt
      841 atcaaataag gagtggaaaa atgcgagcag cagacttatt gacaattctt acaaaatcac
      901 ccaaaaaaac agagtatcaa ggagtttttt tggctcaaga acaaaaactg gtgcctgtga
      961 caatggtcca gataaataaa gcaaatcaat ttatcttttt atttgaacac ggcaaagcac
     1021 cacttgctat gaaagacatc tttctttttt tgatgaagaa ccgtgagaaa gctgtttatt
     1081 atcagtcaaa agaagaactc attcctcttt atggagtgaa agagatagaa aataaagtgg
     1141 tgatataagt aaaaataaga aaacaagacg tttatgatgt caaaacaacc attttttaca
     1201 tttttggcaa aaaagtgtca tgatacagta taatattcgt tgaacaggcc aataaaggtg
     1261 ttctccccca cgagatttct actttattgg ctgtttcttt ttattaaaat aaaagttgtg
     1321 tgtgtaaaaa agatatagct gattccaagt gacaatttcg tatagatttt tatggtattc
     1381 gtagtgaaaa aacgagaacc aaaaagttga tccgactttg ttgcttggat tctttttttg
     1441 tcagcatatt tagaggtatt tttttctttt ttttgttcgt gctgtaaggt taaggcaaga
     1501 caagttagtt gggaaaaagg aaagaaatgt ttatacttaa agaataacag aaaggaaggt
     1561 cgcatgaata attttataca aacattaagt gaaagaaaag gcgagttgct ggaagctgca
     1621 tttcaacatc tgtccatttc tctcatttct ttgctgattg cagcactgat tgctattcct
     1681 ttagcgattt gggcagccaa tcataaaaaa atggcagaag tcttattgca gatcacgggt
     1741 gtgctccaaa cgattccttc acttgcctta ttaggtttac ttatcccatt tgtagggatc
     1801 ggaactgttc cagcattgat tgcacttgtt atttacgctt tgcttccgat tttccaaaac
     1861 acgtatattg gtctagctga aattgacccg tctattgaag aagcagcggt agcatttggt
     1921 atgtccagaa tgagacgctt gctgaaagta gagcttccca tcgcattacc tgtcattatc
     1981 tcaggtatcc gaactgcctt agttttaatc atcggtacgg ctactttggc agcattgatc
     2041 ggagcaggtg gattagggac atttattttg ttaggtattg accgaaatac acctgttttg
     2101 acattgattg gtgcgatcag ttctgccttg cttgcaatta tattcagcgg actgattcgc
     2161 tggttgcagc ataagaaacc tcgatattcc atcattactt tagcagcagt ggtgtgttta
     2221 tttggcggcg tttctttata tcagtctgcc ttgtttaaaa atgaaaccat cacgattgct
     2281 ggaaaattag gagcggaacc tgaaatcctg atccaaatgt ataaagaatt gattgaagac
     2341 aacacaaaaa cagaagttga attaaaaccg aattttggca agacgagttt tttgttcaat
     2401 gcactggatc aaggtcaaat cgatatctat cctgagttca caggtactgt cctagaaagc
     2461 ttggtgaagg tacctgaagc aatgaaaagt gctgatttga caaaagaaaa aacatatgac
     2521 gaagcagaag aattattgaa taagcaattc gatatgacat tattaaaacc aatggcttac
     2581 caaaatacgt atgccttggc agtcaagaga tcttttgcga acgaacatca acttaaaaag
     2641 atttccgatt tggcagctat ctctgatcag atcaaagcgg gattcacact ggaatttatt
     2701 gatcgttcag atggatataa aggaatccaa gaagcatatg gcttgaattt ttcaagtgta
     2761 caaagcatgg agccaagttt gcgttaccaa gcaatcaata atggagatgt caatattgtg
     2821 gatgcctatt ccacagatag ccagctcaag gagtacgatc tagtgactct agaagatgat
     2881 cgagggttat tcccagctta tcaaggcgca ccgctgatga aaaaagattt tgctaaagaa
     2941 catcctgaaa tcgttaaagc actgaataaa ttaagcggaa aaataacaga ggatcaaatg
     3001 attgatatga attaccaagt caatgtcgaa aagaaaaagc cgacagaagt agcacgaatc
     3061 ttcctgaaaa atgaaggatt agtaaaggag gaagatcagt gactaaatta atcgagttca
     3121 aacatgtgca aaaaaagtat gatggaaagt atgtcatcga tgacctaaat ctggcaatca
     3181 aaaaaggaga aatctttgtt ttggttggtc cttccggtag tggaaaaaca actactttga
     3241 aaatgatcaa tggattatct aaaccatcag caggagacat ctacttcaaa ggaaaatcgt
     3301 taaatgaata taatctgcag aaaatgcggt ggaatatggg atatgtgctg cagcaaatcg
     3361 ctttgttccc gaccatgaca gtcaagcaaa atattgaagt catccctgaa atgttaggtt
     3421 gggaaaagca gaaaagagca gaccgtgtag atgaacttct tcaaaaagtt ggcttatctc
     3481 ctgatattta tcgagatcgt atgcctagag agttgtctgg aggagaacag caacggatcg
     3541 ggatcatccg agctattgct gcaagcccag atgtgatttt gatggacgag ccatttagcg
     3601 cattagatcc gatttcaaga aactcattac aagaattggt tttgtcctta cacgaagaat
     3661 tgggcacgac catcgttttc gttacgcaca atatggaaga agcaatcaag ctaggtgatc
     3721 gtattgcatt tatgaaggat ggagaaatta tccaatgtga cacaccagag cagttattga
     3781 tgaatcctaa aaacgactac gttcggcatt tctttgatga accgaaacag acgaaagagt
     3841 ggcgagtaga agatttagtc gtcaatggat atttcttaaa tgaaatacca gaaaatgctc
     3901 gtcaacaagt ttgctttgat acgcctatga aagaagtata ttcgcttctt tcggtgtatc
     3961 caagcattgt gatagtagaa aagcaaagaa gtattgggtc gctgacaagt aaagaaatct
     4021 ttgctttttt aagtcgagag gaggaaggaa atgaaaacat atgatgcaat catcatcggt
     4081 tcaggtgtga gcggcttaag tgctgcttat ggattgaaag aagcaggtaa aacagtacta
     4141 gtggtcgaag aagatctatg gggcgggact tgtcctaacc gtggatgtga tcctaaaaaa
     4201 gtcttgttaa gtgcagtaga ggcacgtaat cgggtaaaac aattgagtgg aaaaggtttt
     4261 aacgagatcc caactgccaa ctgggaagaa cttcaaaaat tcaaacgaac atttacggat
     4321 ccagtcccag aaagccgaaa aaaacaatta gcagaagctg aaatcgatca tctttcagga
     4381 accgctcgtt ttttggatga ttcatctatt gaagtcaacg aagaagtctt ccatgcggat
     4441 tacttagttt tggcaaccgg gcaaagacct acgatcttac cagtggaggg aaaggaatac
     4501 ttgaaaacta gtgcagactt tttatcattg cctgtactgc ctaaagaaat catttttatc
     4561 ggtggtggtt atattgcttt tgagctagct acgattgcca atgctgcagg gagcaaagta
     4621 accattgtcc atcataatca acggccatta aaagaatttg aggcgtcttt ggtagaggaa
     4681 gccgtccatc aaatggaagc atctggcatt cagtttgctt ttggtgttga aacccaaaag
     4741 atcatttcag aaggtactcg ctatcgttta gtcggaaaag agacggaatt agtagcagat
     4801 atgatttttt gtgcgactgg gagacagccg aatacagaat ctttagcact tgagcaagcg
     4861 aatatcgtct ttgataaaca cggaattgca gtcaatgatt atctgcaaac gagcaatcca
     4921 aaaatttttg cgtgtggaga tattgtttca aggaaaaccc caaaattgac accagtcgcc
     4981 acttttgaag gaaattatgt agctaagcgg ataacggatg caacaagcga acctatcaaa
     5041 tatccgatta tacctacgat cgtctacgcc agtcctaaac ttgctgaagt aggagttaca
     5101 aaaagtcacg cctcttcgtc agatcaagtg gtagagatgg atcttaccag ttggttcacc
     5161 tatcatcgtg tcaatgaacc agttgctaag gctgaattga cctttgacca gcaaaattat
     5221 ttgattggtg ctgcagtgat tagcgagcaa gcagacgaat tgatcgatga tttgacactc
     5281 gtcatcaatc aaaaattgac taaaaaagag ttggatagct atatcatggg gtatccgaca
     5341 ttggcaagtg atctctccta tttattgaaa taatcagcat gataactaaa gcgcttgttg
     5401 ctttttcctt cttgtgctac actttaaaaa atgaatacct gtttctgggg atgtcgtaga
     5461 cgacatgaga gtaagttgtg aacttagacc cattgaacct gtcagttaat actggtgaag
     5521 ggagaaacat agcagacgct tgaagcgggt tactatgtcg tgcccatttc aagcgttttt
     5581 tgttattcat attagaagaa aggaggtaac aaaatgaaga aaaatcttta tccagcagtc
     5641 agtatggcat tcattttaat tatttggcag attgttgtca tagtttggaa aatacctgcc
     5701 tttattttac ccggacctgc tgctgtattt tctgcattag cggtagatgc acaagtatta
     5761 ctttcccatt ctgtcacgac attaaatgaa gcagtgcttg gtttggtaat agctagcgtt
     5821 ctttctttta ttactgcctt ggcaatggat tattggaagt ttttagaaat gtctttttat
     5881 ccgttactag tgatttcaca aatgttgcca atcatggtgt tagggccatt acttacccta
     5941 tggtttggtt tcggtatgct tccaaaagtg atccttgttg tcttgataag ctattttccg
     6001 atcgtagttt ctttttcgga tacattgagg aaagtatcaa aagagcaaat catctttttg
     6061 aaaacgatgg gggcagatac agggaagatt tatcgaatat ataaaatacc agcgggttta
     6121 tccggcttct tttccggttt aaaagtggct gctacttatt gtgtcagcgg agcagtcgtt
     6181 ggagaatggc taagcgctca agcaggctta gggtattaca tgatacgcgt aaaaaacagc
     6241 taccagatcg ataaagtttt tgctgcgatc atttgtgtca ttctattgag tttattgctg
     6301 aatggcgctt gttcattatt gaaaaaaggg tattatcgta tgctttatat tttttaagag
     6361 aaggggatca aatgaaaaaa ttatggcttt tattaccgct actgttgctt ttatccgctt
     6421 gtggcactgc aaaagaaaca agtagcaaac aagaaataaa ggatttgaaa aaagtgacac
     6481 ttgttttgga ttatgtaccg aatactaatc atactggcat ctacctagca aaagaaaaag
     6541 gctattataa agaggctggt ttaaatgtcc aaatcatcga accaggagat aattcgacaa
     6601 gtattggtct agtaggtgcg gacaaagcac aatttggtgt aagttatcaa gaagatgtca
     6661 cttatgctca cgcagatgga cagaatatac cagtcaaagc aattgctaca gtgatcaaac
     6721 ataatacttc tggattcgcc accctatcag acagtaacat ccattcacca aaagattttg
     6781 aaggaaaaac atatgcaggt tggcaaagtc caagtgaaga agctgtctta aaagctgtga
     6841 tggaaaaaga cggcggggac ttttcaaaac tgacaatggt aggaagcaat ggagaagggc
     6901 cagaaagctt aggaaaatcc tcagatatcc aatggtactt tgaaggttgg gatatgatca
     6961 aagcaaaaga agcgggtatt gaactaaact atatcccatt gaaagaatta gatgaacggt
     7021 tagattacta tactccggta attattacga atgatcaact gatcaaaagt gatccagaat
     7081 tggtacagtc ttttatggat gccacgaaaa aaggctatca ggaagctatt aaggatccaa
     7141 atgacagtgc taaactgttg caaaaatatg caaaagaaaa tgatcggacg tttttagaag
     7201 aatcacaagc attcttgtca aaaaattata cggatgatcc tgagaattgg ggattgatgg
     7261 aagaaaaagt ttggcgcaat tatacagctt ttatgcagga aaacggattg atcaagcaag
     7321 atgtaccttc gcaagaacta ttcactaatc agtttataaa ataggagtga tagatatgtc
     7381 aatccaaatc agccacttga atgtagtcat tgaaaacctg aaaatattag aagacatcca
     7441 tttcactatc cctaaagata cctttacatc gattgtcgcg ccaagcggag ccggtaagtc
     7501 aacattgctg aaaactttaa caggagtcca gcctatgact tctggaacga tcaaagtaga
     7561 cgatcaaaaa gtaactggtc tccatacagc atttagttat atgccgcaag aagatatgtt
     7621 acttccttgg ctgagcgtct atcaaaacgt tacgttatat caaaaaatca atcatctaac
     7681 aatcaatgaa gaacaagtaa gggattatct ggatatcttt gggttaaacg gctatgaaca
     7741 ttttttgccg gaacaattat ctggcgggat gaagcagcga acggccttgt tacgaacaat
     7801 catgaatcct tcttcttact tgcttcttga tgaaccattt ggagcgttag atgctatgac
     7861 cagagggcag atgcaagact ggatgttgaa gctgcctaaa aaagcaaagc ggactacttt
     7921 acttgtgacg catgatatcg aagaagcaat ttatttatca gacaggattc ttgtgctttc
     7981 cgcccgtccg gcacatgtga ttgctgagat tcaagtgcct gaaaaacgac ggtcacgtga
     8041 atggctactg cagcaatcag agttgaagca aacgatttat cagttattgg caggtgaatt
     8101 agatgttaag tgatgctcat tgtcatttag atgggagtca gagtttagca ctccttcagc
     8161 aggaacacac gattttgacg atcatcaatt gtgattcgcc agaagaatgg aaggaaaaca
     8221 gacagcttgc agcaagtaag actcaagcct taagttacgg tatccatcct tggaaagcag
     8281 atagctatac gtttgaacaa gttgagcctt ttttgaaaaa agcaaggatc atcggtgaaa
     8341 tagggttaga taatatttgg acgaatgtac cgatgactac acaaaaaaaa gtatttgagc
     8401 gacagcttgc ttttgcagcc ataaatgaga aacctgttgt actgcacaca aaaggatgcg
     8461 aaaaagagat cttaaattat atccaagctt accctaatca ctatttgatc cattggtatt
     8521 cttctttgga ctatcaacaa gactatattg atttaggctg ttatttcagc attggtcttg
     8581 atttgaaaaa gaatccagca gtctggcaac tagctaaagc agtcccaatc gaccacttac
     8641 ttattgaaac ggatggacta catgcagcag agtgggcttt aggggggatt ttttcagaaa
     8701 aagattatgt ctcactgctt gaagaacagt taaagacaat cgctgagatc aaagagctat
     8761 cagttgaaga agttaaaaaa aatacttatc aaaacttgga acgtttcatt agattaggta
     8821 aataaaaaag agatgtgaca caactagtgt cgcacctctt tttggctttc tttgtataaa
     8881 agtaaactgt ttgattaata aatgaatctt agtaccaacc gtttgcttcc cagaatgctt
     8941 tcgccgcttc ccaagaacca taacgtgaag taacatattg ttctgctact ctttcttggt
     9001 ttgcagcaga gtagtcacca tttaagtaag aagaatctaa ttggtaacgt ccgatgtaac
     9061 gtccgttcgt tgctgtgtaa gaaccgcttg attctttttg tgcgatccat tcttttgcag
     9121 agcttgtgct tgctggagta gcagcagttt ctgttacagc aggagcaggt tgtgtttcag
     9181 caacaggcgc tgcttgtttt tccgtttgaa ccgtttcttg tacaacaggt tgttcagctt
     9241 ggactggtgc ttcttgaacg gctgcttgag gttcagcagc tgcttgtgca gagccttctg
     9301 ttgggattgt taattgttgt cctgagta
//
LOCUS       DADVXM010000088         9277 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.093, whole genome shotgun sequence.
ACCESSION   DADVXM010000088 DADVXM010000000
VERSION     DADVXM010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9277
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.093"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(943..1356)
                     /locus_tag="KB927_002300"
     CDS             complement(943..1356)
                     /locus_tag="KB927_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBB6841196.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="KB927_002301"
     CDS             complement(1812..2297)
                     /locus_tag="KB927_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841197.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="KB927_002302"
     CDS             complement(2436..2651)
                     /locus_tag="KB927_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBB6841198.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="KB927_002303"
     CDS             2875..3675
                     /locus_tag="KB927_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6841199.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="KB927_002304"
     CDS             3694..5562
                     /locus_tag="KB927_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBB6841200.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="KB927_002305"
     CDS             5555..6046
                     /locus_tag="KB927_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBB6841201.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="KB927_002306"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="KB927_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBB6841202.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..7601
                     /locus_tag="KB927_002307"
     CDS             6606..7601
                     /locus_tag="KB927_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBB6841203.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
     gene            complement(7743..8993)
                     /locus_tag="KB927_002308"
     CDS             complement(7743..8993)
                     /locus_tag="KB927_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBB6841204.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     ETILEFNNSYHFDQIVIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFS
                     RMFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQH
                     FLENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGK
                     GRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQ
                     VIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQ
                     SQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARK
                     FTRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT         3200 a         1510 c         1773 g         2794 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg agtttagtct aatggtgata
     7621 agtcaagatg aaatttaaga ttttctttat tgagtaatat gttttgaagc gcacgaaact
     7681 agacccgatc aaaatcaaat ttttttcggg ttgattcaag gatttgcgtc aataacggat
     7741 tgttatttct ctatcacact ccttggtggc gtatagagtt ggtgtttacg tagtagcgta
     7801 tccaccagac gcgtaaattt tcttgcggtt aggacgagtg cacgtttgtg ttgatgcttt
     7861 ggaacctcct tatatttact ttgataaaaa gctttgtatt caggaagata attttttaca
     7921 gagttggcag cttcaactaa gtagtatcta aaatatcgat ttccttgttt tgtcagaggt
     7981 gtattttgcg actgatagtt tccagattgg ttcactttcc aacttaatcc agcgtatttt
     8041 gccaattttg tctgatcttc aaatctttcg atttgaccaa tttcagcgat taaaccggca
     8101 gcatagactt taccaacgcc tggaatactg gttaagcatt gatattctgg aatgacaaca
     8161 attacttgtt cgatggcttt atctaattct ttgatatttt tttcaagtgc tcgtatttct
     8221 cgtacgagaa cacttaaaac aacattaatt gattcttgtg caagagcacc taggcggtaa
     8281 ctcatggtaa ttgcacgttg aattgcttta gcgatttttt ctggttgctt gaaacggcct
     8341 tttccttttt cttgaagtaa atcacagaaa gcttctaaag gaagctcagc aagttcatcc
     8401 aatgtgaaat cttccgtcat gagtgaaatg agggttgcac taaaaagact cgtcgattcg
     8461 tctcgcattt ctcgagcaag cgtattacat ttgtacgtta gattttcaag aaaatgttgc
     8521 tttgtacgaa tcaattgctt aataagttga tagcgagtac gtgttaaacg ctgtaaggcc
     8581 atgtatttct cttctttgat aggggaagtt gtgaatcgtt gaatacgcaa gaaatcagcg
     8641 attcttaatg catcgtttcg atcagtttta ttctcatcaa acatgcgact aaattgtttc
     8701 acccgaaaag gattttcaat cgttacaagt gtgttgagct tctttagttt ctcatcttca
     8761 tgaaaaaaca tggaaggatg gaagctgtac atggacgttg actccatgcc aatcacaatt
     8821 tgatcaaagt ggtagctgtt attgaattca agaattgttt ctcgtatgaa tgaagcacct
     8881 tcgatgtcat tggcaacaga gatttcagat aagatagaca attgattgtc gtctgttaaa
     8941 aaacaaacat ctagtttttc agagctaacg tcaataccga caaataattt catggaagaa
     9001 ggacctcctt tcgatataaa ttttggaaaa tgcttcgata ctgtgggatt tcccagaaac
     9061 tcactgtata gccacaacct cgcctaatag aatacggtga taaaagagct agaagctgcc
     9121 ttccaaacta ctatttgaaa gtctagtcca ttatcgaaac agctaatgag ttggtagtga
     9181 taacagtggt tcgggtaaca gactaaacag ggtagacaaa cgctacagga ggaaatagca
     9241 aattcccgtt ggatcctttc catacatcca ttgtact
//
LOCUS       DADVXM010000089         9170 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.094, whole genome shotgun sequence.
ACCESSION   DADVXM010000089 DADVXM010000000
VERSION     DADVXM010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.094"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            134..307
                     /locus_tag="KB927_002309"
     CDS             134..307
                     /locus_tag="KB927_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841205.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            947..1420
                     /locus_tag="KB927_002310"
     CDS             947..1420
                     /locus_tag="KB927_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBB6841206.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1429..1656
                     /locus_tag="KB927_002311"
     CDS             1429..1656
                     /locus_tag="KB927_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6841207.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2292..2663
                     /locus_tag="KB927_002312"
     CDS             2292..2663
                     /locus_tag="KB927_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841208.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2919..3161)
                     /locus_tag="KB927_002313"
     CDS             complement(2919..3161)
                     /locus_tag="KB927_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6841209.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3193..4095)
                     /locus_tag="KB927_002314"
     CDS             complement(3193..4095)
                     /locus_tag="KB927_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6841210.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4108..4296)
                     /locus_tag="KB927_002315"
     CDS             complement(4108..4296)
                     /locus_tag="KB927_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBB6841211.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4310..4873)
                     /gene="amaP"
                     /locus_tag="KB927_002316"
     CDS             complement(4310..4873)
                     /gene="amaP"
                     /locus_tag="KB927_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBB6841212.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4911..5804)
                     /locus_tag="KB927_002317"
     CDS             complement(4911..5804)
                     /locus_tag="KB927_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6841213.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5882..6805)
                     /locus_tag="KB927_002318"
     CDS             complement(5882..6805)
                     /locus_tag="KB927_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6841214.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6854..7204)
                     /locus_tag="KB927_002319"
     CDS             complement(6854..7204)
                     /locus_tag="KB927_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6841215.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7237..8139)
                     /locus_tag="KB927_002320"
     CDS             complement(7237..8139)
                     /locus_tag="KB927_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBB6841216.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8132..8989)
                     /locus_tag="KB927_002321"
     CDS             complement(8132..8989)
                     /locus_tag="KB927_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBB6841217.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
BASE COUNT         2571 a         1736 c         1509 g         3354 t
ORIGIN      
        1 ttcggagaat taaaaaatac aataaataac tttagttact ttaatgcgtt cttactttat
       61 ttttatatta tcatttttct tattcacttc tttggtttat actattctta taaataaaaa
      121 cgaggtatgt cctatgatga aaagattgta ctattcattg atcataacga ttggctattt
      181 gattgtatca aatctaggaa atatggtatt tggtatcagt aaagaattca gttggactac
      241 tacattatgg gaatctctat tctttttcat cttcgtattt ttgttacaaa attatcgaaa
      301 aaaataaaca tgtgccatct atctgttggc acatgtttta ggatttatgg tactttttat
      361 tcggcaatcc attttatttt tctacttctt cttaatacct ctaacacttt tgatttataa
      421 actaatccaa tgcatctact tgcgcttatt aagctatttc agctagatag taccacccca
      481 tgcgtcaatg cttgattttc cttttgtata acattgtata agcaataaag gacaaataag
      541 tggtgattac accaaaccat tgaataagaa aaattctgat acgtaaataa acatgaactt
      601 gaaaaaatta atgaatcggt tagctactac gtagttgtct tttttctcat acagttctgt
      661 taacttacac ttctcttcgc tagataataa aaaatcctcc aactgtattg tccaatataa
      721 tcccaggcat ctaaactagc attatagaag agacacacat agaatctaaa ataactggtt
      781 ttaaatgttt cttacaatca aaaaaagctg ttaaatgcac tccacacctt catactctat
      841 cattttttat aaacgatata tttttattgt ttttcgataa aaaatagttg ttttacaata
      901 attattctgc tatattttag ctatcaaaga taaaagaggg ataaaaatga aatttaaaac
      961 attgctatta aaatttgtcg ttttaggtat aagtgccgta tttattttgt tcggcgtact
     1021 tttttatact cagatcgcta caagcgaaaa aggattcaat tttgattggc agaccacatt
     1081 atttgtttct gtcatttact ttgcccttct cctagggatc gttattgctt atttcttatt
     1141 gaaactattg aaaaaaatcg aagataacca agctttttcc actcaaagct taaacatact
     1201 aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc ttttttggct tacttcctaa
     1261 atttatgaaa gtagcggatt tagacgatgc tccaggtttg atgttggtag gaatcgctgt
     1321 cgtattcatt ccttttgcag tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca
     1381 tgcgatttta cttaagacag atcatgattt gacagtgtga ggtgcgacat ggcaattatc
     1441 gttaatttag atgtagtatt agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa
     1501 gtgggcatta cgatggcaaa catctctatt ctaaaaaatg gaaaagcaaa agccatccgt
     1561 ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc
     1621 tataaaaatg actcgaatac tataccagaa gaataaaata aagtagaaca aacagtaaat
     1681 aaaaaataat ctgaatgata gatgtgtgag acttttagaa gttatttacg tctattattc
     1741 agatttttta tttcgattga ataccgtttt atctataaat aagatatgta ctgactcata
     1801 caaagggggc cttttcttct ccatgtacta tcacttttcc tgatacaact ggtttcctgt
     1861 tacgttgtag ttggatctgc ttttagtata atactttatt cattccacca gactgatagc
     1921 agtttgagca gtctaaataa tcatgtagta ttacaggcca ttctgtttca taccttgaag
     1981 tgcttaaaac ttcagctaat ggcccattgt gttaactctt actccattct tttttagtaa
     2041 gctcccatat atactgtaaa gccttctata tattatgtca tgttgctttt taacatttac
     2101 tatgtagttt tgataaaatg atttgaataa cagtgatgga caattctttt ttatttttaa
     2161 cattattttg ataataatga ttatttattt aaaaatacat tagataacat ttgttacgac
     2221 acgaaaaagc ttcacaaaca aatatcgtta ttttaaaatg agggcgaact cacacaatta
     2281 ggaggaatag tatgccattt attgtttact tttttctttc attactcgtg atctatattc
     2341 cattaccaac atttttcctg ctcgtcaatc gtctagcaga gcaacatgat acgattgctg
     2401 ctcttacgaa actttgttta cttctatttg tttgtctaga ttactttacg agctattatt
     2461 ggctaaaaca gacaagagta aaaaagagat attatttctt ccttgtcttt ttcaatctct
     2521 ttgagtttct gatccattgc tttttacttc atcagtatca tacgatccat ttgtggatca
     2581 tctgggtttt caaagtggtc gtattatttt gtatgttcac ctttcctatc tcaagaaaat
     2641 ttagggaggc attgttttat taaagaagct tctctgtatc aataaagaca catttaagga
     2701 aaaactttta aaaatctaat tgggaatttg cccgcataaa taagaggctg tgacaaaagt
     2761 cttgtcacag cctcttattc cgtataaaca gtgttcaaaa gcttgcatct tcgataatat
     2821 gcccaaccaa atgaaaaata tgagaagcta tttttgtttg gctgttctta ttacttgatg
     2881 aagaacagct ttttcacgac ctctttttaa aagtcttttt acagttttcg agcaaagaat
     2941 gatacgatta gtactaaaat gatggcacca atcaatgatg gcacgattgc cattcctgca
     3001 atacttggtc cccaagaacc taataatgct tgaccaagtg ctgatccaac taaacctgct
     3061 acgacatttg caataatccc catcgaagaa cctttattcg tgattgctcc tgcaattgct
     3121 ccgataattc ctccgacgat aagtgaccaa ataaatccca tgtttcgttc ctcctaatgt
     3181 tttacttcct tattactgaa cccgtggttc tgtattttct tttacttttt gtgcgccgct
     3241 tccagctgct gattttactt tatctgtttg attcgaagca aattcaccgg tttttttcgc
     3301 tgcgtcagtt actttgtctt gcaccgtttc ttgatctttt tcaaattctt cttttgtttt
     3361 gatgtccact acgttagcgt tgacttcgat cacttctaaa tgtgtcatat tttttacttc
     3421 tttgccgatt acttcttgca tttcttcaaa gattttttcg atatctttgc catattccac
     3481 aatgacatcc atatcaactg ctacttgttt tttaccgact tctgtttcga tcccagccgt
     3541 tacattatct gtattcacaa gttttcctgc cacattagag aagaaaccac cgtttgcaga
     3601 taataaaccg tctacttgtt caattgcgat tccgatgatt ttttgcacaa ctttatcttc
     3661 ataattcagc tcaccgcgca ttgaatcttc ctgttcagaa tcatgctttc cttggttatt
     3721 tgtatgatca gaaccaagtt ttccttgtcc gtttgtgtgg tcagaactaa gtttttcttg
     3781 tgctttcgca tggtcagaag gatgtttttg ctcttccaca ggtttagaag gatcgattgc
     3841 atcatgttgt tctggaactt tagattctgg agttcctgga tgatgaggtg catgcttttc
     3901 tgcatcatgt ttcttctctt ctactccttg ttgaacgtta gggactactg gatctggatg
     3961 tgcagatact ggtgctgttt tgttcttttc atcgttcaca ccatttgatt ggtttggtgt
     4021 cgttgggtct ggatgtgcag acactggttt ttggttgttc attttattgt tattattttt
     4081 gttattgtta ttcatggatg tttcctccta agatttaaaa tagtgatcta agattttcgt
     4141 ttgtttcaga taaaaaccga tagcgacgcc gatcgctgcc atgatcaaga tcaataaggt
     4201 cttgaaaaag cccacggtga tccataaaac ggctaatatc aatccaagta ccccaaagat
     4261 gatagggagc ttgtatgtcg aaaatagttc tttcattttt ggtccccccc tattctactc
     4321 gtttgcggtc attgcttcgt ttagctggtt cttcaaagcc tgtgtatttc accgatactt
     4381 tcactggctc ttttgttccc aatatgtgtt gtacttcatt ttcgatttct ttcatcaatg
     4441 ttcctgtttt accaatgagt gctgaagttc gtttcaactc cccttttaca ttgacggcga
     4501 tcttgttttt cgttgctttg acatttactt ttggtgaatg gatgaattca tcttcatgca
     4561 agtgagaacg aaccattcct tcaattgctt ttttatccaa cgtcaactcc ccatcaccat
     4621 gtttcagtag aaagtttccg attgtttttg gataaaacag gaaaacaagt aacgtgataa
     4681 ttgtcaaaat agcaaatgca acggcaagcc aaaatacata ttgttgcacg tatgaattag
     4741 tgatggaaaa gaatcgaaac ttctctagct gaaaaggcaa tggataggtt gcacttaata
     4801 gtatcgcaaa caaaagcaca gatagcaaaa gtaatgttcc gatcactccg atcgttttta
     4861 cacctttatt cattttcgca cctcctcata ggggtgaaac gatcaacttc ttataagttg
     4921 atcgcttctc caccagttac tccgtaaatt tgggctgtaa cataacttgc tttattcgat
     4981 gctaagaaaa cataaactgg tgctaattct cctggctgac ctgcacgttc tagtaaactt
     5041 tgctgaccaa attcagggat cgaatcagaa ggttgtcctt cgtctagttg taatggtgtc
     5101 cagattggac caggtgctac accatttaca cggattcctt taggtgcaag ctgttttgct
     5161 aaaccgatcg taaagttagc gattgaagct tttgttgctg cgtaatctaa taaatgttcg
     5221 cttggattga atgcttgaac agaagttgtt gttacgattg ctcctcctgc tgggatatgc
     5281 ggaacagctt ctttcactaa agcaaacata gcgatgatgt ttatcataaa tgtgtctttg
     5341 acttgctcaa gtggtaactc agcaatagac tgacaagaaa tttgctgtcc tgcgtttagt
     5401 accatcgtat ctagcccgcc aagttcactc acggctttat ctatgatttc tttaggtgct
     5461 tgttcgtcac gaagatcaaa aggtagtaag acaatcttac gtcctgcatc tttcacgtat
     5521 tttgctactt cctctgcatc tttttcttct cctgggaaga attgaagagc gatatctgcc
     5581 ccttctctag caaatgcaat cgctgctgca cgaccgatcc ctgaatctcc accagtgatt
     5641 agtacacggc ggttttctag ttgattattg ccttcatagg attcttctcc acaatcagga
     5701 acaggaatca tattctgctg taaagctggt gtatcctgat cttgtttagg aaatttctcc
     5761 gtatggtaca agtttcgcgg gtcgattaat tttggttctg tcattgctgt attcctccta
     5821 gtttttaaat tgtattgcca aaacaaattt ctttgtttga tacctgtttt aaatagattc
     5881 tttaatttgt ataatctttc cggtataaat ggtaacctaa aactactgct gctatcaaag
     5941 agccaaagac tacgagtata aagcctagag cagaactttt acccggtaat cctcctgtat
     6001 tcattcccca aatccctgcg aacaacgccg gaacggaaat gattaatgca gctgaatcta
     6061 gatatttcat gatatgattt agattattgt ccatcatccc gttgaataga tcaccaatac
     6121 tctctaataa atctcgatag atctcgatca ttttttctgt ttgtcgctgt ctcaaatgga
     6181 catcatagag tagctgttca tcgtctaaac gtttgatgaa agtttcagaa ttccataatt
     6241 gatccattgt ttcccgttga tctcttaagg tatgatcgat atatacgatg tctctttcaa
     6301 gatctgcctg tttatacagt tcttcatttt ccgttgtttt acgagctgct ttatccaaag
     6361 cgtcaattcg ctttttcatc tctcttagtt ctttcacgta atgggtgtaa atatctaata
     6421 atgtatacgt gatgatcttt tcaaacgagt ttaaatgatt tccatgcttt gtcagcagcc
     6481 gatccacaaa ttcggttttt ctatcgatac aagtaatcaa gagattatcg gaaagtacaa
     6541 aagatattgg cgttaatttt ttttcgatac gattatctga ctgatctaga ttaatcacta
     6601 ccaaagaaaa tggatgctct agtttcgtct cataaaggcg ctccatccga gaaacttctt
     6661 ccggatattc ggttcctacg aaaatatcat caggaagctc gaattcttcg attgcttgct
     6721 caatctcttc gggctttgca ctatcaagta cgagccaatt atattttttt tcatctgttt
     6781 ctattacatt cttttcttca tccacaaagt agtatctcaa tgtatacctc ctttttggac
     6841 tttctcgaaa ctattagctg aagaagcagt tctttaattt gatattataa tcgagtactg
     6901 cgatttcatt ttctaatgaa aagctgtcaa gctgtttgtt gaagtccatg ttcaatcgtt
     6961 taccgaaata attttgctct aatttagatg tatagatgtc caataatgga tgctcgattt
     7021 tagtcgcata ttctccaaat tccgaaacaa aaggaatgat ttgaaaaaag ctgccttttg
     7081 caaaagcacc tttgtccctt agaaatggat cggaatcatt gataagcgcg agtgcgattt
     7141 ttgtattttc cccaaccttt tcaattaacg tctctactgc atttttagac attgtaattt
     7201 ccattcctac tccccctctt cagttgttgt cttctattat ttaacaacta catctgtttt
     7261 tggttgaact tttgcatatt ttggatattt agggaattta gctacacaac ggaaagccgt
     7321 catccctgca tatttttcgt aatatttctt cgttggccct tcaaaatcct tgctccacgg
     7381 tttcacatgt cctgaaaaat ggataatgta aggattgttg cgagtttctt cgtattcacg
     7441 ttcacctgct gctgttggat gtttttttgc ttttgccatg atatagcctt gtgcattcca
     7501 acgcggatga agtggtaacc aacggtcatg taagatagca tttaatgcat cttggtcatg
     7561 gaatcgtaat ttttctggat tatgttcgat gaaatctaat actttttgcg taatattttc
     7621 atctaaccat tttttcacat tgatcagcat caaacctgag ttgaaataac gcattgattt
     7681 agctgaaatt ttcatttttt ccagtcgttg atggaaccca gcgtcttcaa cagctgctac
     7741 gattgaatca ccgaagtcaa gacgccataa tttagagata tcttgtaaag cgatcatgtc
     7801 gcaatccata tataagatac gttcaacttc tgtgccgcgg aacaattccg gaatcgcaat
     7861 acgataataa gctgtttctg gaatacgatc gctgattacc acatttgtaa agaattcttt
     7921 attgattttc aagaattcca catctgagtt cattcgtgcg tttttcactg agaagcgtaa
     7981 aagctgttta ctttcaaaat cgatatcatc gtcaatcaca tagaaccgaa caaatttaga
     8041 cgggttgcaa ttatctaata ctgagacaaa taatgcagct aaatgtggta cgaattttgt
     8101 gttacaactt gcgactactg ctatttcttt tttattcatt gatctcgcct actttcgtta
     8161 gagtactgtg tgctaatttt tttaagtata aattggtata cggatgatct ttcaacgtat
     8221 tccaaggttt atcatgtcct gtaaagtgaa cgatcgaagg tttttcattt ccttctttat
     8281 actgacgttc atatttttca tttggtgctg gatgacgttc aaaaatcagc gaagtctgca
     8341 tgttccattt tggatgaagt tgttcccaat cttcataaag tacagcattc aaagcatctt
     8401 ggtcgtgata gatgattcga tcgccatttt cactgaggta atggatagtt ttttctgtaa
     8461 tttctttttt attccattga tcaatgtcaa tcaccatcac tcctgaattg aagtacaagt
     8521 catcggaatc gattcctaat ctttccaaag ctttcacttg gcctggatcg ataatagcgc
     8581 cgattgtttt tccatttaac ggctcatcat atagttttac gatatcgtct agtactaaca
     8641 catctgaatc taagtaaagg actttcttat aatcctcttt agctaataag tttggtaaag
     8701 aaattcttaa gtaagcggta gttgtgatat ggtcactgac taggaagtct tcgtagatat
     8761 ctttttccac tgtcaggaat tggatacttg cattacttga atatttattt accgtttctt
     8821 ccaatccttc tttactatat tctgatagac catcgtcaat cacataaaat tttatgcgtc
     8881 ttgttttatt gcaattttct aatgcagttg cgatcatcac gctcaagtaa ggagcataat
     8941 tttcgtctga agcagttacc acaggaacta cgccgtatct cttctccatc aaaatcactc
     9001 ctttttctaa tctttttcta acctgttcta catctagaat attcctcatt tggttttaaa
     9061 gcaaaatata tgctttgttt tcattgaata ttttaaaatt tttttatcac aaaacgcatc
     9121 ggtaagcgct aactattcgt ttttcatggc tttttattca aaggtattga
//
LOCUS       DADVXM010000090         8986 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.095, whole genome shotgun sequence.
ACCESSION   DADVXM010000090 DADVXM010000000
VERSION     DADVXM010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.095"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(15..1154)
                     /locus_tag="KB927_002322"
     CDS             complement(15..1154)
                     /locus_tag="KB927_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBB6841218.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1553..2851)
                     /gene="eno"
                     /locus_tag="KB927_002323"
     CDS             complement(1553..2851)
                     /gene="eno"
                     /locus_tag="KB927_002323"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBB6841219.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(2967..3722)
                     /locus_tag="KB927_002324"
     CDS             complement(2967..3722)
                     /locus_tag="KB927_002324"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBB6841220.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(3826..5016)
                     /locus_tag="KB927_002325"
     CDS             complement(3826..5016)
                     /locus_tag="KB927_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBB6841221.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(5126..6127)
                     /gene="gap"
                     /locus_tag="KB927_002326"
     CDS             complement(5126..6127)
                     /gene="gap"
                     /locus_tag="KB927_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBB6841222.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(6168..7259)
                     /locus_tag="KB927_002327"
     CDS             complement(6168..7259)
                     /locus_tag="KB927_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBB6841223.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="KB927_002328"
     CDS             complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="KB927_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBB6841224.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            8802..8873
                     /locus_tag="KB927_002329"
     tRNA            8802..8873
                     /locus_tag="KB927_002329"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8835..8837,aa:Arg,seq:ccg)
BASE COUNT         2330 a         1895 c         1660 g         3101 t
ORIGIN      
        1 ttattaaaaa aatcttacgc taagtaggat aaaataattc cttgatattt ttcgatcata
       61 tccaaataat tatcgatttc aacatactca tctacttgat gaggcaaagt aacgacacca
      121 ggcccaaaga cgacaaagtc gaaggaatgg ttagctttcg taaattcggc tgcatccgtt
      181 gttgctgccg ctccaactaa aggtaatggc tggctgaatt gttgctgaat gcaatgaatc
      241 aaaggagaat ctggatcagc tttgacaggt attttgttgt aatcgatcat caattccaaa
      301 tgatagtctg tctcttgatt caattcattg acgattgatt gcagcaatgc aatgatttta
      361 tcatttgggt attctggaat cgatcgaatg ttcccttgga gctgcgcatg gcttgggatg
      421 ctgttgactt gattcccgcc actgatcaat gtaacattat ggattgtttt tcctaggaca
      481 ggattctcga ttgtttcagc gaggtgattc atttcagcat ttgctttcgt aatgaattca
      541 tttaggtgat tgattgcatt ataaccttgg tctggcatag agctatgcgc ttcttttccg
      601 tgcgaggtga ctgtatagtt gattgatccc atgtgcgtat acatcaaact gtaattggtt
      661 ggctctccga tgatcaaggc atctaagtca tctacatagc ctgctttcgt gagctgttcc
      721 ccacctagtt cacccacttc ttctccgaca gtggctaata atttgactgt tccgttaaat
      781 ggttttcctg actctttcag ttcgatcatg gcaatcacca ttgctgccaa gccactcttc
      841 atatctgtag caccacgtcc gtacaaacgg ttcccatgga tttctgctgc aaagggtgca
      901 taggtccaag acgattcatc accagccgcc acgacatcca tatgtccaga taggcctaac
      961 acttttcctg attggccctt ttggtaacga gcaatcaaat tatctctacc atctctgtaa
     1021 gaaacaatct ctcctgttat gtcatgcttt gccaaaagct tattcaaata ggctgctact
     1081 tcaccttcgt ttccattcac tgatttaatt cggataatct cttgtaaaat cgcgattttt
     1141 tcttcttttt tcatctaatc ctctcccttg ccatttcttt ttattgtatt tgagtgtgct
     1201 cgaattttca aataggagca accaaagtaa aaatgaagaa agagagccac tttatgaaaa
     1261 atatgctgct acttccctcc tattttattt atacgagagg acttgcccat agattcctat
     1321 tctactgttc tatccttaaa agctcttata tgatgctagt tattgttagc tttccttttt
     1381 caaggatgat cttttcttgt accattcttt gtaaacatca tatacagaag ctagttgcaa
     1441 aaaaactctc tacctgctga tatttcagca agtagagagt tcgattactt aactaagtga
     1501 tcatactcga ctatctttca atagtcgatc atgtatcttc attagaaaag aattatttgt
     1561 tttttaagtt gtagaaagat ttcaaacctt tgtattctgc aacttcacca agttggtctt
     1621 cgatacgtag taattggttg tatttagcaa tacggtcagt acgtgataga gaaccagttt
     1681 tgatttggcc agcgtttgtt gcaacagcga tatcagagat tgttgaatct tctgtttcac
     1741 cagaacggtg agatacaact gctgtgtagc cagcttcttt agccatttcg atagcttcga
     1801 aagtttctgt taatgtaccg atttggttca ctttgataag gattgagtta gcaattcctt
     1861 tttcgatacc ttcagataat ttttgagtgt ttgttacgaa caagtcgtca ccaactaatt
     1921 gaactttgtc gcctaatacg tcagttaatt tcttgaatcc gtcccagtcg ttttcgtcta
     1981 atccatcttc gattgagatg attggatatt tagaaactaa ttcttcgtag aatttgatca
     2041 tttcgtcagt tgttttttcg ccttcgcctg agtcagctag tacgtaaaca cctttttctt
     2101 tgtcgtagaa ttctgaagaa gcagcatcca tagcaagaac aacgtcttta ccaggtacat
     2161 agccagcttt ttcgattgct tcgatgatta cttcaaaacc ttcttcgttt gaaccaaggt
     2221 ttggagcaaa tccaccttcg tcaccaacag aagttgctaa tccgcgagct ttcaagattg
     2281 aagctaatgc gtggaatact tcagcaccca tacgtagagc ttctttgaat gttggagcgc
     2341 caacaggcat gatcatgaat tcttggaagt cgattgagtt atcagcatgt gatccgccgt
     2401 tgatgatgtt catcattggt gttggcaata cttttgtgtt gaatccgcct aggtagtggt
     2461 ataaaggtac ttctaggtag tcagcagctg cacgtgcaac agcgatagaa acacctaaaa
     2521 tagcgttcgc acctaattta cctttgttag gagttccgtc taaagcgatc atagctttgt
     2581 cgatagccat ttggtcacga acatcgtagc caatgattgc ttcagcaatg atgttgttta
     2641 cgttgtcgac agctttagtt acacctttac cgccataacg agctttgtct ccgtcacgta
     2701 attcaactgc ttcgtattca ccagttgaag cacctgaagg aaccattccg cggccaaaag
     2761 ctccgctttc tgtgtatact tctacttcga ttgttgggtt accacgtgag tctaagatct
     2821 cgcgagcgta aacatcagta ataattgaca tgttttgtct ctcctttgag tttgtttttt
     2881 cctaagggat ttccctcata tacgatttta gttaattttg ctcattagtg caaacatttc
     2941 ttgcattttt cgcaaatttt caacaattat tttacagcgt ctaacaatga caagaatgaa
     3001 tctgcttgca agcttgcgcc accgactaaa gcaccgtcaa cattttcttt tgccatgtat
     3061 tcagcaatat tttctggttt tacagaaccg ccgtattgga tacgaactgc ttctgatact
     3121 tcttttccat aaagtttttc aactgtttga cgtacaactc cacaaatttc gtcagcgatt
     3181 tgtgcgtcag ctgatttacc agtaccgatt gcccagattg gttcataagc aataaccatg
     3241 tttgacactt gttcagctga aagatcagct aaaccagctg taatttgtcc ttcgatccat
     3301 tcagcagttt tgcctgcttc ataggtttct aaagattcgc cgcagcatag gattggtgtc
     3361 ataccatttg caaagatagc ttttgctttt ttattgatgt cttcgtctgt ttcatggaaa
     3421 tattcacgac gttctgaatg tccgatgatc acataatgaa cacctagatc agcaagagct
     3481 gctggtgaag tttcaccagt gaacgcacct gagttttccc agtagcagtt ttgtgctgag
     3541 atttttagtt ctgtaccttc agctgatgtc attaattctt gtaagaataa tgcaggagat
     3601 ccgatgactg aatcaacttt gtcatttgaa gggattttgt tttttactgc ttcagcaaat
     3661 tcttttgctt ctgatgcagt tttgttcatt ttccagttac ctgcgataat aggtttacgc
     3721 attgaggaac acactcctta atttattgaa aaatggctag ggagtcatga aaactccctt
     3781 caccttttga tcgattactc gtcagaattg agcaaacttg gtcgtttatt tatcgttgat
     3841 tgctgctagt cctggtaatt ctttaccttc aagcaattcc aagcttgcgc caccacctgt
     3901 tgagatgtgt gtgaatttgt cagcgaatcc taattgttct gctgctgcag ctgagtctcc
     3961 gccaccgatg attgttgttg cgccttctaa gttagcgatt gcttcacaaa caccgattgt
     4021 acctttagca aagttactca tttcaaatac acccataggt ccgttccaaa caactgtttt
     4081 tgcaccttgt aatgtatcag caaataattt tactgatgct gggccgatgt ctaaagccat
     4141 caaaccatca ggaatgtctc cttcgattac ttgtgtttca acatcatttg aaaattctgg
     4201 tgcacagaca ttgtcgattg gcaagacaag tttgtcgcct gctttttcga ttaattcttt
     4261 tgctagttct actttatcag cttctactag agagttaccg atcttgattc cttttgcttc
     4321 gtagaatgtg taagtcattc cgccaccgat taagatttta tctgctttag gaatcaagtt
     4381 ttcgattacg ccgattttat cagaaacttt tgcgccacca aggattgcaa tcattgggcg
     4441 ttttggttct tctactgctt caccgatgaa cttgatttct ttttccatca agaatccagc
     4501 aactgttggg ataccagttg aagcgatacc tacgttagaa gcatgtgcac ggtgagctgt
     4561 accgaaagca tcgttaacaa atacatcgcc taatgaagcc cagtatttac ctagttctgt
     4621 atcatttttg ctttcttttt taccgtcaat atcttcaaaa cgtgtatttt cgaatacgac
     4681 aacgtcgccg tcattcatgt tgcggattgc ttcttctaat tgttctccgc gagtttcagg
     4741 tacgaatgtt acttctttac ctaataattc gcctagacgt tttgcaactg gagctaaaga
     4801 ttttccttct ttatcttctt ctgtttttac acgtccaagg tgagagaaaa ggattgcttt
     4861 tccgccttgt tctagaacgt agttgattgt tggcaatgct gctttgatac gagtgtcgtc
     4921 agtgatcacg ccgtctttca aaggaacgtt gaagtcaaca cggacaagaa cttttttgtc
     4981 ttttaaatcg atatctttca ctgttttctt agccatttta tttcctcctg aataaactta
     5041 ttatcaaaaa aagcggaaga agcgcgattg cttccccgct tttaaatgta catgtctata
     5101 atttacactt gtacgtttgt ctatcttata agttagcgaa gtattctaaa gtacgtacta
     5161 attgtgcagt gtatgacatt tcgttgtcgt accaagcaac agttttaact aattgtttgt
     5221 cgccaactgt cattacttta gtttgtgtag catcaaataa tgaaccgtaa gtcataccaa
     5281 cgatatctga ggaaacgatt tcgtctgtgt tgtatccgta agattcgttt gaagcttctt
     5341 tcattgctgc attgatttcg tcaacagtta cttctttttc aagaactgtt actaattctg
     5401 ttaatgaacc tgttggtaca ggaacacgtt gagcagctcc gtctaattta ccgttcaatt
     5461 cgggaattac taaaccgata gctttagcag cacctgttga gttaggaacg atgtttgcag
     5521 cagcagcgcg tgcacggcgg aagtcacctt taggatgagg tccgtctaga gtcatttggt
     5581 cacctgtgta agcgtggata gttgtcatta atccttcaac aacaccaaat ttgtcgttca
     5641 atgttttagc cataggagct aaacagttag tagtacatga agcacctgag ataactgttt
     5701 ctttaccagt taatgtttcg tggtttgtgt tataaacgat tgttggaaca tcgtttccgc
     5761 caggagcaga gataacaacg cgtttagcac cagctgttaa atgtttttca gctgctgatt
     5821 tagaagtgaa gaaaccagta cattctagaa cgatatctac gcctagttcg ccccatggta
     5881 attcttctgg gttgcggtta gctaatactt taacttcttt tccgtttacg ttgaatgaac
     5941 cttcatgaac ttcaactgtt ccgttgaaac gtccttgagt tgtgtcgtat tttaacaagt
     6001 gtgccaacat tttagcatct gtcaagtcgt tgattgctac tacttcgatt ccatctacat
     6061 cttggatacg acggaatgct agacgtccaa tacgtccaaa accattaata cctactttaa
     6121 ctgtcattta agatttcctc cttatgaaaa tcaaaaaaat atttatttta aagggttacc
     6181 ccttttaaaa tctcatttgc agcagcttca tcagtgatga gccacgtttg ttttggtgca
     6241 tttttcatat aagctcgaat tgctttagct tttgattttc cgcccgcgat tgccatgatg
     6301 atcgggactt tttccaaatc ttgcaattct atgccgattc tagggacctt ataaacgact
     6361 tcaccttttt cattgaaaaa gtagccaaaa gattccgcaa cagcatttgc ttgtttcagc
     6421 atgactaatt ctttttcagt catcttacga cgtgctgcca tgtgtaatgc acgcccaata
     6481 ctatgaataa cacaattcgc ttcactaatc aagtttaaga cttcttggat agatggctca
     6541 ttgagtaaag aattgtaagt tgccagactt aattgttccg gaacataaag tgcgcggtgg
     6601 ttaccgtttg ctttagcagc cattcttgca ctgacagaat ttgcctgtac agttatcgct
     6661 tcaccaatcc cgcctcttgc agggacaaac aggttatgcc gtttcttatt ttccagatta
     6721 gacaattgtt cggctaccac agccatagta gttcctccca tcacagcgat gatattctcg
     6781 ccttctggaa gtagtcggtc taaggcttcg ctcagcgctt cgccgaatgc atcagccact
     6841 ttggtctgct cttcgctgtt tcctgaaaca acgatacagc gttggttacc aaaatattct
     6901 gccaactgtt gttcggtttg atgcgtacct aaaagctgat ccatgaagtt ttcaaggctt
     6961 tgataaactt cttcgccctt agttgtcagc gtcataccgc tttttgaggt gtcgatcaaa
     7021 ttcagatttt tcaaaaggtc tgtttctgtt cgtaagactc gttctgtgat ccccatactt
     7081 tccgataaac ttcgacgccc aatcggctgc atccaataga tatttcgtaa aattttatag
     7141 cgttcttgca acacttcgat aatatctggt gcaacagatt caatcatttt tatttcatcc
     7201 agcatagcga tctccttagt tggacacttt acgtccaatg tagacttaaa acgacccata
     7261 tacgataaaa aaagaaatta actattcgaa tttcacatca ataaagggaa atctcaacct
     7321 cacgactgta agtctaacag ttttgctctc gtttttcaac taaaaagact agaaaaagtg
     7381 aaatactttt tctagtcttt tgactgatta gttatcataa cgttttcttt ttgatgaact
     7441 cgggattcct aataaatcac gatattttgc tactgttcgt cttgagatcg ctatctcatc
     7501 ttttttcagc aattcaacca atttctggtc cgacaacggc ttgtttttgt cttcttgatc
     7561 gactaattcc tgcagctttt tcttcgctgt atctgctgaa aggtcttctg tctgttctgt
     7621 actattcgta ggaattcgtg tagtgaaaaa tttttttaat tcaaatacac cgaaatctgt
     7681 ttccaaatat ttcccgttga ctgcacgact gaccgtggat tcatgcacat ctatctcagt
     7741 tgcaacttcc tttaacgtaa gaggcttgat tggacgttcc ttgtcgataa agaaagcttt
     7801 ttgccgggaa acaatgactt gagcaacccg caaaattgta tccccacgtt ggaggatcgt
     7861 tttcttcaac cattcgaatt cctgtttccg ttcttttaaa taattttcag tttctttatc
     7921 tgcttgttgt gacatttgtt tgaagtaact ctcttgaaag cgtatatttg gctgattttt
     7981 tcggtttgag ataacttgta catttttatc gtcgtccact aatacccgga catcaggaat
     8041 aatgtacaat tcgctgctac ggtcgaaaat ccggccaggg cttggactca acgtttgtaa
     8101 atagtcgaat atctgctgaa cagcatgtag atcaacagaa aaacgttgtg cgatttcttt
     8161 ccattttcgc tccaccagtt cctcaaaaca ttcttccaac acgatataag ctaattccgg
     8221 cgcataatca tctcgttctg tttgaagcat gagacattct tgcaaactac gtgcacctac
     8281 tccagctggt tctaattgct gaatcagagt caacgcatcg agcatttgga taggcgtagc
     8341 tccaatctct tttccggctt cttctaaact aatcgtcaaa aatccgttca aatcgatgta
     8401 ttctacaaga taaagaacga ttttcctcaa aaaagtatct cggtaattca aatggacttg
     8461 ttcgatcaat gaatcaaata aagacccttt tgtatcagga atctgattta ggtaatttgt
     8521 ctcttctcct tcataagaag atgaagaagc ttttatgtaa tctggctgcc attccggctc
     8581 aacaacttcc accaatggat tttccattgc ttgattctca acgaatgcca acagctcctc
     8641 actgttatat tgtaaaactt ggatggactg ttgcaactgt tgcgtcatgg ctagtttctg
     8701 tgtctgctgc tgtttttgtg aaaaattttg ctcaaatttc atttttttgt ccaatcccct
     8761 tgtaattttt tatctgttta gttacaatta tcccagtgct tgcgtcctta gtgtagtgga
     8821 tatcacgtaa gattccggtt cttgagacgg gggttcgatt ccctcaggac gcgttctact
     8881 gctattttag cataatttac gaatagttgc ttctttattt ttaagtgaaa actgtccgcc
     8941 aaagagaatt ggtggacagt tttttgttgt atctgtatag atattg
//
LOCUS       DADVXM010000091         8733 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.096, whole genome shotgun sequence.
ACCESSION   DADVXM010000091 DADVXM010000000
VERSION     DADVXM010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.096"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            2..74
                     /locus_tag="KB927_002330"
     tRNA            2..74
                     /locus_tag="KB927_002330"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="KB927_002331"
     tRNA            78..150
                     /locus_tag="KB927_002331"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="KB927_002332"
     tRNA            155..225
                     /locus_tag="KB927_002332"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="KB927_002333"
     tRNA            238..311
                     /locus_tag="KB927_002333"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="KB927_002334"
     tRNA            323..394
                     /locus_tag="KB927_002334"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="KB927_002335"
     CDS             660..1853
                     /locus_tag="KB927_002335"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBB6841225.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="KB927_002336"
     CDS             1983..3455
                     /locus_tag="KB927_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6841226.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="KB927_002337"
     CDS             3538..4326
                     /locus_tag="KB927_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBB6841227.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="KB927_002338"
     CDS             complement(4393..5061)
                     /locus_tag="KB927_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBB6841228.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="KB927_002339"
     CDS             5176..6888
                     /locus_tag="KB927_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6841229.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="KB927_002340"
     CDS             6891..8663
                     /locus_tag="KB927_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6841230.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2623 a         1487 c         1945 g         2678 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattttttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaacggt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcatgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc aga
//
LOCUS       DADVXM010000092         8609 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.097, whole genome shotgun sequence.
ACCESSION   DADVXM010000092 DADVXM010000000
VERSION     DADVXM010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.097"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(217..651)
                     /locus_tag="KB927_002341"
     CDS             complement(217..651)
                     /locus_tag="KB927_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6841231.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(883..1593)
                     /locus_tag="KB927_002342"
     CDS             complement(883..1593)
                     /locus_tag="KB927_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBB6841232.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1583..2443)
                     /locus_tag="KB927_002343"
     CDS             complement(1583..2443)
                     /locus_tag="KB927_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBB6841233.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2448..3086)
                     /locus_tag="KB927_002344"
     CDS             complement(2448..3086)
                     /locus_tag="KB927_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBB6841234.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3101..3400)
                     /locus_tag="KB927_002345"
     CDS             complement(3101..3400)
                     /locus_tag="KB927_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6841235.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(3443..4927)
                     /locus_tag="KB927_002346"
     CDS             complement(3443..4927)
                     /locus_tag="KB927_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBB6841236.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(4947..5408)
                     /locus_tag="KB927_002347"
     CDS             complement(4947..5408)
                     /locus_tag="KB927_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6841237.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5426..6493)
                     /gene="ulaG"
                     /locus_tag="KB927_002348"
     CDS             complement(5426..6493)
                     /gene="ulaG"
                     /locus_tag="KB927_002348"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBB6841238.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            6711..7481
                     /locus_tag="KB927_002349"
     CDS             6711..7481
                     /locus_tag="KB927_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6841239.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(7754..8581)
                     /locus_tag="KB927_002350"
     CDS             complement(7754..8581)
                     /locus_tag="KB927_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6841240.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
BASE COUNT         2592 a         1826 c         1348 g         2843 t
ORIGIN      
        1 aataaaaaaa attatcgcat agcatttgct ttaaaaaaaa atcatgtgtt cattttttat
       61 attagttcga atttgcaaaa aattgtattt gataaagagg tgagtaaaaa aataaaatag
      121 ctgagcattg gaggatagat tgagtgatac taagtctatc ctcttgtttt tctaaagaac
      181 taagctagaa ttttttcttt tgtacgttat tatatgttat ttgtcattac caaaaagcac
      241 cttttttctt ctagtatcta tgacataaga aataccaccc atttccttta cttgaacaaa
      301 tcctactgat tcataaaatt tttttgtttt ctcagtatca tctgtcaata attcgatttg
      361 gactggtcca taactagtga tcttctccaa agcttcattc aaaagcactt tgcctattcc
      421 ttggcgctga tacctcggat gaatgaggat atcttgaata aatgcgatcg tcgcaaaatc
      481 agtgatccaa cgaacgattc cgataatctt cccttcccca ttacgcttta tcagagattc
      541 agattgttca aatgctctag ctaaccttgc agtgtctttt gtgtaattcg tccaaccaac
      601 gctcttatat aattcagaaa tctcatcgat cataagggaa tcaatattca tttttttctt
      661 cctttcttat acaattctcc ctctaataat acagttcttt gactatttaa tctatcacat
      721 ataactctcc tgtaaagatt ctctcgattc cttaaaattc ctctttcctt ttagaatgca
      781 tactttttga taaataaaaa ggttgtgata aattttcttc acaacctctg tttctctcta
      841 tcaagtgtta tcttttaatt ttctaccctt accctagcat ctctattgcc cgtagtatgc
      901 atactttcca tgtttgcgaa aataatgttt atctagtaaa tattgcggga tttcacatat
      961 attggggttg atcagctcgt tttctttggc catcagacaa atttcatcta agatcaaact
     1021 gttttctact gctttcatag gtgaatcccc ccatgtgaac ggtccatgtc catagacaag
     1081 tactccaggg acttcgtttg gatctaattt tctttcctta aacgtctcga caatcacatt
     1141 ccctgtatga acttcgtaag cttctcttac ttcttctttc gttaattggc gtgtacaagg
     1201 aaccttacca taaaaagcat cagcatgagt cgtgccataa gctggcaaat cgcgtcctgc
     1261 ttgcgcccac atgacggagt gcgtggaatg agtatgagta atagcagtta tatcttcaaa
     1321 agtttgatac aaaacaacat gtgtggggag atctgaagat ggttttaagc tatcttcttc
     1381 tattatattt cccgacaaat ctgttaccac catttgatct gcttgcatgc attcatatct
     1441 gacaccgctt ggcttaatga cgatgactcc tagctcacgg tccacttcac tcacattgcc
     1501 ccaagtcaat ttgactaatc cgtatcgcgg caatgccaga tttgcttcaa ggacacgttg
     1561 cttcattgct gcaatttttt cttcacaaga catcatagcc agcctccttc aatttagaac
     1621 ttaagtagtc ttttgcctgc tggatttctc ttcgaaagtc ttggcttttt tcactccaca
     1681 tttcaatcag aaatgttcca tcataatcta gacgtttcaa atgtcttaat aatccaagaa
     1741 aatcaacaca accgctacca aaaggaacat cacgaaactg gcctgaatat tcttttgtta
     1801 cagggtaagt atcttttaag tggatagcag tgatataatc gatccctttc tcaagttctc
     1861 gagccggatt attttccggc catgcggaca aattgcctag gtctggatat acttgtagaa
     1921 aaggtgaatg aatctgttct ttgatttcta aaaattttga aatggagttc ataaatggat
     1981 catccatgat ttccacggaa agaatgatgc catatttaga agcttccttt acgctttctt
     2041 ttattccttc gataaagtct tctctggaat tcattgattt ctcttcataa taaacatcgt
     2101 atccagctat ttggattact ttgacgctta gattatgcgc caaatggatt gcttttttca
     2161 ttagttgttt cgctgctttt ttcttttctg gatcagcaga accaaacgga aatcgccgat
     2221 gcgcacttaa acaaatcgaa tggatacgta caccggagct gaacatctct tctctcagct
     2281 cagctatctt ttcttcagac caatctaatc gtgctaaccg ctcatccgtc tcatcaatcg
     2341 acatctcgat aaaatcgaag tccatttctt ttacaaggga aaaacgttct ttccatgaaa
     2401 tatctttggg taacgctttt tcataaatcc caatttgagc catttcctta cccccagata
     2461 cgaatgatct catctttgaa gttttgtgcg gccttcatcg gatcatttgc tgctgtaata
     2521 ccacgaccag tgataaaggt atacacatcg atcccttcaa ataagtgtaa tgtgtgtgga
     2581 tttaatccac cagttacaga aacattaaag cctagttcaa tcagtttttt gatcttcgat
     2641 aaatcttttt caccccaagt ttcaccagat aacagcgcat cacggctttg atggtagatt
     2701 acctgccgga taccgatgtt atgccaatcc atggcttgtt caaaagtcca attgccgtag
     2761 agttctactt gcaattcacc tatttctttt tgtgctgcct ccatagttgg aatcgttgca
     2821 caacaaatga ctgtcatcca gtctgctcct gcttttgcaa cattactcgc cactgttcct
     2881 ccagcgtctg cacatttcgt atcagcgact agttttttat ctgggaacat actgcgaata
     2941 cagcgaatcg ctttttgtcc ttcctgtaag caaagaattg tgcccacttc aataatatct
     3001 actacatcac caactttcat aacatctcct aatgcatgtt ctaagtcatt gtgatctaac
     3061 gcaatttgca aattcggcct gctcatctta gttccttcct ttacttgttt ttttggtacc
     3121 actttgtttc agcaaatttt tcactgattt ctttgactga catcacattt ttgataccga
     3181 taactgtaac tccttttttc tctgcctgag taaacatatt caaaaaattg actggcgtaa
     3241 aaactacatc gtattggcca gctgaacttt ttccctctga aatggcacaa tgatggattt
     3301 tggtaattgg tacgtttagt tctttcattg ctttttccac acttctcatc atcatcaagc
     3361 ttgttcctga tccatttgca cacgatacta aaattctcat cttaatccct ccattatgag
     3421 tgttgtctaa tcagattttc ttttatactc tctgcttttc tgcatatgtg tcatagtctt
     3481 ctacaatcaa aaaataacca tcaggatttt tccgatattg taactgcgga atagccaata
     3541 aaccaatgac aactacggca attccagcat aacctaggac tttcatgatt actgtaaaca
     3601 atggccaagc tgttgcccag tcgaacatcc cgatataacc accgtatgtt gacatcccaa
     3661 tccatgtagc gaataatgct gaaccgccta cttgtatgat tcctgaaaga aacgggaaca
     3721 ggcaagcggc tttgaatcca cctcggttat tggcataaac tgctataacg gcattatcaa
     3781 agaacaacgg aatgaaaccg gctatgacga tcgttggtga tttcaataaa atcagtaaac
     3841 caatcatcaa aaactgtccc aaagcaccaa acaagaaccc aatcgttacc gcatttggcg
     3901 aaccaaagcc aaaagtagca gctacgtcaa ttcctggaac agctcctggt aaaatcgtgt
     3961 ttgagattcc ttggaaagat tgagttagtt catcgacgaa tgtccgaaca cctaattgca
     4021 agatcgccag atataccgca aaatttaaag aagtcgtcat aatgtagaat aagaaactct
     4081 gcccttcttg catgaattgc gcttgaatca aataatcttt gcctagtaca atcagaatga
     4141 tcccaaagaa aaatagcatg agtaacgaag tagcaaccat attctcattg aaaatcgaca
     4201 agaatcctgg taatttgata tcttcaattt ttttgtcttg cttgattgat ctatttttct
     4261 tttcatcccg ctttttcatc cactcagcta attttgcaaa tataaagatt ccgaacattt
     4321 gctgatgtgc cactgcaaat ccggcacctt ctgtcaattc ctgcgtgatt cctactgtta
     4381 agttagaagc tactgcccaa taacaaccta aaatcagtcc cataaaaatc aatacttgta
     4441 tcctacctag atcaggaaag caaaacagta aaatccaaaa agcggtagct gcttgttgaa
     4501 cctgaacgtt tccggtagtg aaaacggaac gcagtttcgt atatttctga aaacggacta
     4561 ataagatatt taaaacaaat gcaatcagta ataaaatcat cacatctcca aaggtacggc
     4621 caaatgtctc cattaatcca gcatccacag cattttgtcc aaaataagga tctgtaacca
     4681 tggcatccaa attgaaccgt tcctttagtc caaccaagat tggccgaaaa ttattgacca
     4741 aaccaccaga gccaacagtc aaaataaagt aaccgaccgt tgcctttaag aatccagcga
     4801 tgcattcatg aagcgggcgt ttcagcaaaa tatagcctaa taacacgata aaaccaatca
     4861 ggtatgctgg ctgcgtcaag atatttgttg caaaatacgt ccaaatgctt aacaaaaatt
     4921 cccccatctt ttttctcctc tatcaattaa ttatattctg ccatcacaac ttggtaatca
     4981 tcgatggagt tcgtagagat gagacgctca accaatccat ctgtcattaa taattcggat
     5041 aatttttgga tattttctag atgttcttct ggatcttttg ctgcgagtgt aaaaaacaaa
     5101 ctagccgttt tctcctcatt ctccccttca ctttcaaaac ggattggctg tttcaacttg
     5161 gtaaatgaaa tagctgttcc aaaaacacca tcactttttt ctgaagaatg cggcattgct
     5221 acttgaggtg cgatcacaat ataaggaccg tatttttcta cacaatggat gatctcctcc
     5281 acatacgttt catcaataat ttccttatcg atcaatacaa gacagctttc ggcgatagct
     5341 tcacgccaat ccgtgatttc tttatctggg taatgaatca attgatggtc aaaaaagtat
     5401 ttcagcaaga aactcccctt ctttcttata aaaacgacgg aaacggtgta tcattttcaa
     5461 tcgagaagac atcttcaaat cctcgataaa aattaaactc aagatcatct ttgtttgtcg
     5521 gatagatgaa tttcccgcct acttgccaga tataaggttt aaatccatac ttcaggcgat
     5581 cctttttgaa tttccaaatt tcagtgatct cttttggatc agccataaaa ttagaccaaa
     5641 tatcgtagtg gacaggaatc actacttttg cattcaatga ctccgccatg cgcagcatat
     5701 caacagaagt aactttgtct gttatccctc gtgggttttc accataggcc cctaaacaga
     5761 catcgatttt gtgttcatta ccatgtttgg caaataaatt ggagtaatgt gaatctcctg
     5821 catgataaag attccctcct gatgtttcga ataaatagtt tactgcaatt tgatccatct
     5881 cctgaggcat ttttcctttt aatacctctt ctggatcttc acaagtgacc aacgctgtcc
     5941 gatcaaacgc ttctaaagct actacattga tgtctttgat tttgactgca tcacctggct
     6001 ttactgtaat cgttttttct tcaggaattc cccatttttg ccacgtgcga accacttctt
     6061 ttggcccaat gaatgttgct tcaggacaat tttgatgaac tgctgcggct gtatggatat
     6121 ctagatgatc ggaatggata tgtgtaacga ttaaagcgtc tacatttttt atcgcaaaag
     6181 gatcgattac gaaaggctga gtacgtaaat taggctgcat attttgaacg ccactcatac
     6241 gcatcatctg atggcctttt ttcatcatgc cattcccatg actacgtttt cccgtcccac
     6301 accatagatc acataaaata ttcgttcctt catgactttt cagccaaatt cccgtacagc
     6361 ccagccacca catagcaaaa gttccaggat ccactacttc tgtttcgatt tcttcattca
     6421 agtatgtgcc ccactcagga aatgtttcta ctaaccactt ttcttttgtt acttcattga
     6481 cagttttact catttgcttg ctccccccat atcgttgttc caacttacaa gtaaatatta
     6541 atgtgtatca gcatccatga aaaccctttt atatgaccgt ttgtttttta tatgattttc
     6601 tttcagtaat caatgattgt ttcagtataa taaagacaga tatgaatgtt taaatgaaca
     6661 actagtcaaa taaatccatg gatcaagatg tccctcagga ggcaaaagtc atgaaaaact
     6721 cacttgtcaa tattgaaaaa cgtcaaaaag aaattttgga actgcttcag cagactgaac
     6781 aactatcaac tttcgaatta gctgaatccc ttgatgtatc tattagtacg atacgaagag
     6841 atttaaattt attagaagaa aaaaacgaga tcatacgcaa ttacggttat tgttcttata
     6901 attacaaaaa ccagactgat tttgatcaat ctggtcctga aaggattaaa caagcgattg
     6961 ccagagaagc tagtaaatac attaacgatt atgatacgct gtttatcaat tctagctcga
     7021 ctgcgttgaa aacactggat tttcttcaat ctaaccattt gacagtcatt acaaacaacg
     7081 tgaaaatcaa ttactctccg cacaaagata attgtagtta tattttaact ggtggagaga
     7141 tgcgctttcc aaaagaagca ctagtgggcg acatcgcatt aaatacgatt tcttcagtca
     7201 atgcagacat ttgtatcatt ggctgtagcg gagtcgatgt agtacatggg gtcacaacaa
     7261 agatattaaa tgaatcaacg atcaacgaaa tgatggtcaa caagacaatc aaatgtaaga
     7321 ttttagtcgc tgatcatcga aaaatcggac tgacatcaaa gttcaagatt gctgatattt
     7381 cagtctttga ttatttgatc actgataaat tttgttctga aaaagtatta gaggagatca
     7441 gaaatacggg gataaaaacc attcaagtag attcatttta agaaccagga cgtaaatatg
     7501 taaataggat tatcaaaaaa atgaataaca aatttatcga taaatgaaaa acacgctacg
     7561 ctcaaattga taaaggaatc ccaagatgta tccatccaat cgataccatc ataatctatt
     7621 gcttctttta taaccgttat atgttgccta aataggaatc aaacaatatc gaaaaaagga
     7681 ggtatgacaa aagtcacacc tccttttttc gaataaacgg tattcaaatc agaacactga
     7741 tttcacaacc actttatttc aggtcgtttt caatcacctt taccgcgtaa tcatttccgt
     7801 tgaaacgcgc tatttttttt gcgtccatat atctttctaa ataatcatct tctcctaatt
     7861 gcttatggca agaagcaatt tcataaagca agtattccaa tgcataagtc gatttatgtt
     7921 tcttattata ctcaataccc ttctcacata attggattgc tttatcataa tcctcgattt
     7981 tacggtaata ggtggcgata tcataatata caatgcagac catcagatta tcaaaatcag
     8041 tctcactcaa tattttaagt gtacgctcca cataaacttt cgcaaaatct aattctcctt
     8101 ttgacaagta gatcattgcc acgtttgcag ctgcttgtaa gtgatggata tctgtttcgg
     8161 tcgtttgttc caacacttga ttaaaataaa ataatgctgc atctggtttt ttcgcataaa
     8221 gatgatcaag cagtccttga taaaataaaa tttgatttaa aagatcagaa ttacttactt
     8281 tttcctgatc gatcgtttgt aaaattttat aagattcttg gtattttgat acagaattca
     8341 atgattgaat ctcatttatt tttttcctga ttttgtcttc ttctgtttct actaatatat
     8401 cggagatctc gacattcagc tttttgcaaa gcgcacttaa gatattgatg cctggcgaca
     8461 tattcttgtt ttcgatattg ctgacagttg cttgttcaca aatgccttct gctaattgta
     8521 cttgtgttaa cccctttttc tttcggtatt cttttagtaa tgctccatct actttaatca
     8581 aaacaatttc cttcccttta aaaaattat
//
LOCUS       DADVXM010000093         8530 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.098, whole genome shotgun sequence.
ACCESSION   DADVXM010000093 DADVXM010000000
VERSION     DADVXM010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.098"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            476..1339
                     /locus_tag="KB927_002351"
     CDS             476..1339
                     /locus_tag="KB927_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6841241.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="KB927_002352"
     CDS             complement(1468..3090)
                     /locus_tag="KB927_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6841242.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="KB927_002353"
     CDS             3339..3860
                     /locus_tag="KB927_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBB6841243.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="KB927_002354"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="KB927_002354"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBB6841244.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="KB927_002355"
     CDS             5941..6759
                     /locus_tag="KB927_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBB6841245.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="KB927_002356"
     CDS             complement(6862..7059)
                     /locus_tag="KB927_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841246.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="KB927_002357"
     CDS             7228..7806
                     /locus_tag="KB927_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBB6841247.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="KB927_002358"
     CDS             7901..8038
                     /locus_tag="KB927_002358"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841248.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT         2590 a         1523 c         1672 g         2745 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacgctt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata
//
LOCUS       DADVXM010000094         8529 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.099, whole genome shotgun sequence.
ACCESSION   DADVXM010000094 DADVXM010000000
VERSION     DADVXM010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.099"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            25..1179
                     /locus_tag="KB927_002359"
     CDS             25..1179
                     /locus_tag="KB927_002359"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBB6841249.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            complement(1201..1953)
                     /locus_tag="KB927_002360"
     CDS             complement(1201..1953)
                     /locus_tag="KB927_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6841250.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(2317..4983)
                     /locus_tag="KB927_002361"
     CDS             complement(2317..4983)
                     /locus_tag="KB927_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6841251.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            5324..6775
                     /gene="cls"
                     /locus_tag="KB927_002362"
     CDS             5324..6775
                     /gene="cls"
                     /locus_tag="KB927_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBB6841252.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            complement(7104..7919)
                     /gene="thiD"
                     /locus_tag="KB927_002363"
     CDS             complement(7104..7919)
                     /gene="thiD"
                     /locus_tag="KB927_002363"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBB6841253.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            8213..8488
                     /locus_tag="KB927_002364"
     CDS             8213..8488
                     /locus_tag="KB927_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841254.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
BASE COUNT         2537 a         1750 c         1509 g         2733 t
ORIGIN      
        1 tatcataagt aaagaggtgt tgaaatgaaa atagggattg atcgtctttc cttttttatt
       61 cctaatttat atttagatat gacagagttg gcagaaagcc gtggggatga tcctgcaaaa
      121 taccatatag ggattggtca agaccaaatg gcagtcaatc gtgcaaatga agacatcatt
      181 acactaggag caaatgctgc cagcaaaatc gtaacagaaa aagaccgtga gctaatcgac
      241 atggtcatcg tcggaacaga atccgggatt gatcattcaa aagcgagtgc ggtaattatc
      301 caccatttac tgaaaatcca atcttttgct cgttcttttg aagtaaaaga ggcttgctac
      361 ggtggcaccg cagctttgca catggcgaaa gaatatgtca aaaatcatcc agaacgaaaa
      421 gtactagtca tagcaagtga tattgctcgt tacggcttgg caagcggtgg tgaagtgacg
      481 caaggtgtcg gtgctgttgc gatgatgatc actcaaaacc cgcgtatttt atcgattgaa
      541 gacgacagcg tatttctgac agaagatatc tatgatttct ggcgtccaga ttatagcgaa
      601 tttcctgttg ttgatggtcc tttatctaat tctacgtata tcgaatcatt ccaaaaagtt
      661 tggaatcgac ataaagaatt gtcgggtcga ggactcgaag attatcaggc gattgctttc
      721 catattccgt atactaagat gggaaaaaag gcattgcaaa gcgtattaga ccaaacagac
      781 gaagaaaatc aggaacgtct tatggctcgc tatgaagaaa gcatccgtta cagccgacga
      841 atcggtaatc tttacactgg ttcattatac ctggggctaa cttctctact ggaaaattcg
      901 aaatcactac agccaggaga tcgcatcggt ctattcagct acggttctgg tgcagtaagt
      961 gaatttttta caggttatct ggaagaaaac tatcaagaat atctcttcgc acaatctcat
     1021 caagagatgc tagattctcg aacacggatc actgttgacg aatatgaaac gattttcagt
     1081 gagacgcttc ctgaacacgg agaatgtgca gaatatactt cagatgtacc tttttcgatt
     1141 acaaagatcg aaaatgatat tcgttactac aaaatataat aaaatcataa aaagaaccct
     1201 tcacgagtcg tgaaaggttc tttttttatc tgcggaccaa aggagcagtc tataggtcag
     1261 cttagtcgta ctaaggattt ctcgtttttc actgaatagt ttgcgaatgt acctggtcac
     1321 aacaggatct tttgcgtacg cgtcatagta tagcttcatc aattcttcag taattgattc
     1381 ctgtgtaaaa taagtaaaat cttttttctt cactttgaat ccttcatcaa ttaagtatgt
     1441 ttcaaattga tccattacaa ctggcgatgt attaggatct tcttctatca ttcctagttg
     1501 cttttcgata ggataaaaaa catcatcgat tgattccact actctgatta tcacgcacca
     1561 tttgcttgac tttttcatca atttttctaa ttgaataaga tgtaccaatg ctggatttgc
     1621 tgctgtaaaa accatttcat atgtctcatt tgattggata aattcttcta acgactgttt
     1681 gataaaggaa acatttggca actcattttt ttctgcttct ttttttgcat tttctagcat
     1741 tcctgaagaa aaatcgatca aatcatagcg attaatttct tttgctaagg aaagaaatct
     1801 gccagatcct ccagcaacgt ctgctgctgt ttcagcaggc aggactttct ccgttttcag
     1861 ataatttttt acatcttcag caatagttac ttgcgattct tgctggattt cataatattc
     1921 ttcagcaaat tcatcccatt ctttttcatt catttgattt cctctaattt tttgttatat
     1981 gttttcactt ttcggaataa atcattctcc tcttttatct attctatctc ttttgatgaa
     2041 taataaaatg attggctttc cgtctatcat aaataaaaaa agggactgtg accaaagtcg
     2101 tgtcaaagtc cctctttccg aataaacagt gtccaatcag atgaccctca gtattagctc
     2161 aaaatgctga ttttacaact tcttccttaa acggtgttct cctgccaact cttcggtcac
     2221 aagtcacaat attcaacaaa catgagaagc tgtttgttga aattgcacct tgtgactcag
     2281 aattaaacgg caggctcaca acctcgttga ttcgttttat ttatttcctt gtactcgtac
     2341 aatgatcaat ttagtgattt ccatcaaaac aattgtcaca agtgcgattc ccatacatgt
     2401 aaagacttct gtcaatccaa atgctgatgg gatagagaag acttctttca gtcctgggat
     2461 cattgttaag cagtaaagcg cgctacatac aactacagct agtaagacac ttctgttaga
     2521 gaagaaccct gcttggatag ctgtttgtgt gtttgaacgt gctgggaatg tttgcaatgt
     2581 ccgacaccaa atcaatgttg aaaatgacat ggctacaccg aattcaggtg aatgctgcat
     2641 gccaagccat tgagcaaaga taacagcaat cccaatcagc acaccacgat acgttacaga
     2701 aatcaatgtt ttgtccgtaa agattcctga atttggatct cttggcgggc ggttcatcgt
     2761 agcaggttca gctttttctg tacctaatgc aattgctggc agtgaatcat tgactaaatt
     2821 gatgaacaac agttgtaatg ctgtaaatgg attggaccag tcagcaacta aggcaaagat
     2881 gatcgcaatg atcgcaccta aatttcctgc aaatagataa gaaatagctt tcttgatatt
     2941 atcaaacaca ttacgtccta cttctactgc gctgacaata gaagcaaagt tatcatccgt
     3001 caataccatc gctgctgcat cttttgccac atctgtaccc gttcccatag caattccgat
     3061 gtctgcttgt ttcaatgctg gtgcgtcatt tacaccatca cctgtcatag ctgagatatg
     3121 acctttattt tgccaagcac gaacgatacg aattttattc tcaggtgaaa cacgtgcata
     3181 aacagtgact ttttctaaaa cttcgtttag ttgatcttct gtcaattcat ctagttccgt
     3241 cccggtcaaa gccaggtttc cttcttcaaa aatcccgatt tgttttgcga tagcaacagc
     3301 tgttgttttg tggtcaccag taatcatgat tgttttgatt cctgcacttc ttgcttctgt
     3361 taccgcctga gtcacttcag cacgtggagg atcgatcata gcaagcaaac caacaaggat
     3421 caaatcgtct tcatcttcaa atgataaatc aaaattatca agtggacggt aagcaaaagc
     3481 tagtacacgt aatgcgcgtg ttgaaaaagc ttcattttgc tcttggaatt ttttcatcaa
     3541 ttcatccgtc atcggaacga cttcaccatt tagcaatact tttttactgc gttggaagac
     3601 gatatctggt ccgcctttaa caaacaagta atttttgtta tcaattgtgt gtccagtaga
     3661 cattaatttt cgatctgagt caaaaggaag ttctgcttgt cttgggtagt tgtttcggat
     3721 ttcctgataa ggctggttta atttttcact aaagtcgata aacgctactt ccgtagggtc
     3781 gcccaattta gtaccgtctt cactgatcga tgcatcattc gctaaaacac tgatttcgat
     3841 caagcgacgt tcgtcagctg tccattttga agggtcattt gtgaaatccc cagtatcgcc
     3901 attacctaaa aagtagtcaa caactgtcat tttgttttgt gtcaatgtac cagtcttatc
     3961 tgtacagatg atacttgtcg aaccaagtgt ttcaactgct ggaagcttcc gaataatggc
     4021 atgacgtttt gccattttat tcgttcccaa agataacacg attgttacga tagactgtaa
     4081 tgcttctgga atagcagcta cggctacggc tacggcaaac atcactgcgc tgacgatatc
     4141 tgcagtcata tctcctgtac cttctccaag ataaatacga aacagttgga tacctaaaat
     4201 caataaagac aatgccaaaa tagccaaact tagtttttta ctgaatttat ccagacctcg
     4261 ttgtaacgga gtgacttgct cagttgttga ttccaaaagg ccagcaactt gtccgatctc
     4321 cgtattattc ccagttgaag tcactaagaa tttaccgcgt ccgtaagtta cgatcgttcc
     4381 actgaatacc atatttgtac gatctccgat tggtaccgta cttgtgatat ccgttacttc
     4441 tttttctgca gaagtcgact ctcctgtcag cataccttca tctactttta atgatcccgc
     4501 atctagtaaa cgtccatcag caggtacata atcgcctgcg tctaacaaca cgatatctcc
     4561 taccacaagt tcgtttgccg gaatcgtttt ttccttacca tcacgaatca ctcgagcatc
     4621 gggcgctgaa aggtttttca acgcttctaa agaaccttct gctttttttg tttggacaac
     4681 actgattata gaattcaaca tcaatactgc aaaaataact aagaattcga tgtagtcacc
     4741 catgaccatc tgaatcagtg cgacaatcag caatacgata accattgcat ctttgaaagt
     4801 ttctaagaac aatttccaag ttggcttctt cggcttttct tttagctggt tcaagccatc
     4861 tctttctaat ttttccttcg cttgcgtggt gctcaatcca tcggttgagc tctgcgtttg
     4921 ctgcatcaac gagtcgatcg tttctttata gaccgcttgt tgtgcttgtt ccttgttttc
     4981 caaatttcat cccccatttt ttgatcttgg ccctagtcct gtctgaaaaa aaagagacct
     5041 aagacaaata cgcatttgtc ttaggtctca ccatttcata caataccaga aaaccatttg
     5101 gttaacttac tgttgatatt atcgcaacaa acgttgccgg ttactcccct aaggagatat
     5161 tcaactgtac taatatccta ccttattaac ctacaaaaag caactacttt agcccgattt
     5221 acctacattt tcatgaaagg agtgaaaagt atattcacct tggtaggctt ctttcttcta
     5281 tcatgctata ctaatgttat tgtatgtaag gaggaacatt tttgtggtat ctagtattat
     5341 aaccgccctt tatctattaa atgcacttat tgctttggtg gctattttga tcaaaccccg
     5401 agatgtagca gccatttggg catggctctt agtattgttt gcccttcctg gggtgggctt
     5461 tgtattatat ttatttttcg gacgtggatt aacggataag aaaaaattct atctccgaca
     5521 aagtgacttg aaagaattag aaaactttca gtcttttaga ggagatacca ttgaacatta
     5581 cgatcctgac atgggcgata aagacaaaca gcaatttgtt gacttcttct cttcattaaa
     5641 tcgtatgccg ctgacaagaa tgaattctgt cactcttctc acagacggac aagagaaatt
     5701 ggattcactg cttcaagatc taaaaaaagc caaacattcg atccatatcg aatattacgc
     5761 atttgtgaca gataatatcg gccagcaagt cttacatgtt ttagaagaaa aagccgcaga
     5821 aggcgtggaa gttcgaatat tatatgatgc atttggctct catggcacaa aagcaaaaga
     5881 tttcaatcgt ctaatcaaaa atggtggaca tgtccataca tttgttacct cacaaagggc
     5941 attacttcgt ttccgattga attaccatga tcaccgaaaa atcgttgtga tcgatggaaa
     6001 gattagttat accggtggtt tcaatattgc caatcaatat gtaaatacaa caaaaaaatt
     6061 cggctattgg cgcgatacgc atatacggat tttcggtgcc gcttcttctt tgctccagct
     6121 tcgcttctta acagactgga acgtctcggt acctgaagaa aaaaaggtcg gctatcattt
     6181 gaattatttc tttaaaaaag cagatcgaga tgaatctaag cttgctgata catccatcca
     6241 gcttgtttca agcggaccga ataacgaaag ggaacaaatc aagctttcat ttatcaaatt
     6301 gattacttct gctaaaaaac gtgtttggat acagacacct taccttgttc ctgatgaaag
     6361 tgtcattgct gctttaaaaa tcgcaactgc ctctggtgta gatgtgaaaa tcatgattcc
     6421 caacaaaccg gatcatcctt ttatttatcg agcaacacaa tattatgctc ggcagctgat
     6481 caaggaaaat gtacaaatcc ttgtctatga gaacggcttc ctccatgcaa aaacattgat
     6541 aatggatgat gaaatctgca tggtaggttc agcaaatcaa gatattcgta gctaccgatt
     6601 gaattttgaa acaagtgctg tcatttacga tcctgagttt ttagaagaac ttgctactca
     6661 gttcaaagaa gatgagacac attgttcatc catgacaact gaaacagtca aggaaatgtc
     6721 taactggcta ttattcaagc aacaaatttc tcgattattt tctccaatcc tataattttt
     6781 ttattcaagt agagaaaaat atactaagat taaagggact gtgacaaaaa tcttgtcaca
     6841 gtcccttctt ccgaacaaac ggtgttctcc tgccaactcc tcggtcacaa gtcacaatat
     6901 tcaacaaaca tgagaagctg ttttttgaac ttgttccttg tgactcggag ctggacggca
     6961 ggctcacgac ctctttctta aacggtgttc aaaagcttgc atctgcggta ataagtccaa
     7021 ccaagttaaa aacataagaa gctgttttta cttggctgtt cttattactt gatgcagggc
     7081 aactttttca caacttcttt cttttactct aattcaccag ctgcccaatg attgatgggg
     7141 ccatatttgt gccctacatt tatttcttca cgaattgcac ggtttacata gtcttttgcc
     7201 aatcggatcg cttgttcaac tgtttttcct ttcgctaact cagctgcaat acatgcagat
     7261 agcgaatcgc cagttccgtt gatccggtcg gtaggataaa atggtgcatt taaccaaaat
     7321 gattttcctg attcgaacaa tacgtagtca ttgactgttt cttgctgcgc atttttagca
     7381 tgatgtcctt tgatcataac gttttttgca cccatatctt gcagttcttt tgctgcttgc
     7441 acaaaatctt cttcagctgc taatgtccgt ccagtcagct tttctgcttc ataaaaatta
     7501 ggtgtcagta cttcggccaa agggacaagc ttttctttca agctttgcaa agcagattct
     7561 tctagtaaaa gatttccatg tttcgttacg attacgggat ccacgactaa tggtccaaaa
     7621 tcatattttt ggtaattttt tacaactgtc tcaatcaact ttgaatctgc tagcatacct
     7681 gttttagctg cacgtatttg aaagtccttc gcaatcagtt caaattcttt gtcgataaaa
     7741 tctgttggca atgtcacact tgctccgatt ccgtaagaat tacctgcaac acatgcggtc
     7801 atgacagaaa caccgtaaac atttcttgta aagaatgtat gcatatctgc ttgcatccct
     7861 gcgcttccat cgctatctga tcctgcgatc gtcattgctt gtacatactg atcttccatc
     7921 aaatcgattc ctccattttt ataaaaagat ttttcataat actgttactg tttctatcat
     7981 atgtttttca aagtatccct cagtaaatat accactacct tttcttggta atcaaattta
     8041 tttgaaaaaa catttgcaat aaatcagaaa atagtggtcg tttatttgta ttcgctattc
     8101 taataataaa taaccactat ttgatttata tatatttcag tatccttctt gttttcatat
     8161 aaccaaaggc gctatgattt ccatatgaaa aaaataaagt caggtgaaaa aaatgaaact
     8221 tgaggataaa aaagtcattt tgaagaaaat caaacgacta ccagaccaaa tagatggcta
     8281 tacgatctgt tctttcaaaa aagacaggag tataaaagct tatacgcaaa acacagaaaa
     8341 aggaataatc tatttcctac atgaagaagg ttacgatacc caaaccttta tgtttactga
     8401 aaaaaaagaa tttcataaac agatgaaaaa actgattgaa aaagaatttc caagaagtca
     8461 taaactctat gtgaatcagc aattttaact tctaactgtt ctttattaat taaaaatgtt
     8521 ctgtaataa
//
LOCUS       DADVXM010000095         8229 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.100, whole genome shotgun sequence.
ACCESSION   DADVXM010000095 DADVXM010000000
VERSION     DADVXM010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.100"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            329..1252
                     /gene="truB"
                     /locus_tag="KB927_002365"
     CDS             329..1252
                     /gene="truB"
                     /locus_tag="KB927_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBB6841255.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1256..2197
                     /gene="ribF"
                     /locus_tag="KB927_002366"
     CDS             1256..2197
                     /gene="ribF"
                     /locus_tag="KB927_002366"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBB6841256.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2592..3377
                     /locus_tag="KB927_002367"
     CDS             2592..3377
                     /locus_tag="KB927_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6841257.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3390..4241
                     /locus_tag="KB927_002368"
     CDS             3390..4241
                     /locus_tag="KB927_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBB6841258.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4365..4817)
                     /locus_tag="KB927_002369"
     CDS             complement(4365..4817)
                     /locus_tag="KB927_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841259.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5282..5650)
                     /locus_tag="KB927_002370"
     CDS             complement(5282..5650)
                     /locus_tag="KB927_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBB6841260.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5800..6282
                     /locus_tag="KB927_002371"
     CDS             5800..6282
                     /locus_tag="KB927_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBB6841261.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6319..7329
                     /locus_tag="KB927_002372"
     CDS             6319..7329
                     /locus_tag="KB927_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBB6841262.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7444..8157)
                     /locus_tag="KB927_002373"
     CDS             complement(7444..8157)
                     /locus_tag="KB927_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841263.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2785 a         1338 c         1667 g         2439 t
ORIGIN      
        1 attaagaaac tgaaaaaata aataaaaaaa aacggaaaaa agactggaag aatggacagt
       61 cttttttttc gtttttggga agtgaaaacc aaactattta cctgtaagcc acccataaat
      121 ccaatcaaat ggtgcaaaga aaaaatcttc cattctattc cctcctttaa aaaaaacata
      181 acatgatttc catttacgtg agcatgaatt ttgttacgtt tttattgccg aaaaataaaa
      241 accgttcatt atgatgtcaa attcgtcagt aattgatgca atgtgttata ataattcagt
      301 taaatcaaaa atgaaatgga gaaaagacat ggacgggtta ttaactttat ggaaagaacg
      361 cggaatgaca agtcatgatt gcgtattcaa attaagaaaa atcttacata cgaaaaaaat
      421 cggacatggg ggtacgcttg acccagacgt agacggtgtg ttgcccattt gtattggaaa
      481 agccacaaaa gttatcgaat atttgacaga ttctgggaaa atctatgtag gcgagataac
      541 tctaggtttc agtacaacga cggaagatcg atccggagaa cgggtagaaa caaaaccagt
      601 agatatgtct ttatctgaag aaaaaataga tgaagtgatg gcttcattta ttggtgagat
      661 cacccagata ccaccaatgt actcagcggt aaaagtcaac ggtaagcggt tatatgaata
      721 tgcccgcaat aatgaaacag tggagcgtcc tgttagaaag gctcagattt accgttttat
      781 ccggacaagt gaattgacaa gagacgaagt gacaggaacc atttcttggc gcttcgaagt
      841 agaatgcggg aaaggaacct atgtccgcac attagctgta gatacaggca agaaacttgg
      901 ttaccctgcg cacatgtctg atctgacccg aacagcaagt gccggtatgt cccagaaaga
      961 tgctctgaca ttagaagaag tagctcaagc tgtgaaaaat gggacaatcg atgattgttt
     1021 gctgccaata gaaaaaggag tgaaacgatt caaacgagta gatattactg atgaagtatg
     1081 gcagaaagta aaaaacggta tgagacttaa ttatactgta tttgcgctcc cagaaatgcc
     1141 gtcagaagaa attgctttgt tttataaagg caaagttgtc agtatctatc agccaaaccc
     1201 gaaagaaaaa aacaaattaa aacctagtaa agtattgaga aatgaggaat aacgaatgaa
     1261 tatcatcaag atcagacatc cttaccaatc agaacaaatt ccagaagacg atgtcgtttt
     1321 agtactagga ttttttgacg gcgtgcatat tggacaccag aaagtcataa agacaggtat
     1381 ggaaattgca caaaaagaag gattgaaatt agcattgatg actttcaatc agcatccatc
     1441 gattgtcttt aaaaagatcg atcctagcag cgtgaaatat ttgactagcc ttaagcaaaa
     1501 agaagaaaaa atggccgctt tgggtataga ttatttatat gaagttgatt ttacttcttc
     1561 ttttgctcat ttagcaccgc aggaatttgt tgatcaatac atcgtagggt tacatgcaaa
     1621 atatgctgtt tccggttttg attatacgta tggaccaaaa gacattgcag atgtcgctca
     1681 ttttcctgaa tatgccaaag gaagattcaa aatcgtcaca gtttctaaag aagaagaaca
     1741 aggtgaaaaa atcagctcta cccgtattcg aggattacta gacagcggac aagtaaaaga
     1801 agcagcaaaa ctattaggtt gcacatatga ggtagaaggg gtagttgtcc atggcgatgc
     1861 acgaggcaga ctactaggat tccctacagc aaatgtcaaa gtaaagagca cagttcattt
     1921 gcctaaagaa ggtgtttatg tatcggaaat aaaaattggg gaaatttggt atccagccat
     1981 gggttcaatt ggacataatg atacattcgg tgaaggacgg gagctgactg tagaattgta
     2041 tattttggac tttaatcaag atatctatgg tgaacatgtc gcagtacgct ggaatcaatt
     2101 tttaagagat caagtgaaat tttctagtgt agaggaattg attgaacaac tcaaagagga
     2161 tgaacaagca acagctgaat atttttctca gcaataaaac attatgcata aaatctcttg
     2221 tttatgtata actagcaatt tcaataaaat gggtgataaa taagcccagg aaaggggctg
     2281 tgacaaaagt cttgtcacag cctttttttc caaataaatg gtttttcaga agtagcttct
     2341 tcggaaataa gccgaaattt cacaaaaatt tgagaagtaa tttttgtaaa ttacttctta
     2401 tttcttgaag ctggccactt ctgtcacaac ctctttcttt atagaaataa aaggacacta
     2461 gcaattcatg aaaacgattg ctaaagcgta tcatttgctt tagactatat atcttggtgt
     2521 acactcactt taagacggaa ataaaagtta tccgtaataa caggtttagg tatgaaaaag
     2581 gagtgggtac tatgtataag gaattagaaa acaaagtcgc agtagtaact ggtggctcaa
     2641 aggggattgg aacagcgatt gctcaacgat tcgggaaaga aaaaatgaat gtagttgtca
     2701 actataactc ggataaagaa ggagcagaaa aagcagtcaa agcaatcgaa gaggcaggcg
     2761 gaaaagcagt ctctgtacaa gcagatgtca gttctgaaga aggaatacag cgtttacttg
     2821 atacggcttt agaaaatttt gggacactgg acgtttggat taataatgct gggatggaaa
     2881 atcagcatcc aacccatgaa cttagccttg aagattggga aagagtatta aaagtcaatt
     2941 tgactggcgt ttttatcgga acgaaagcgg ctttaaatta ctttacagag aatgataaaa
     3001 aaggaaatat catcaatatg tcttctgttc atgaacaaat cccatggcca acgtttgctc
     3061 attacgctgc ttcaaaaggc ggagtaaaac tattcaccga aacggtagca atggagtacg
     3121 caccaaaggg aatcagaatc aatagtatag gacctggtgc tatccgtaca cctattaatg
     3181 cggcaaaatt tgatgatcct gaacaaaaag aactcttgga aagtatgatc ccactaggac
     3241 gcgtaggtga accaaaagaa atagcggcga cagctgcatg gttggcttca gacgaatcca
     3301 gttatgttac aggtattaca ctatttgcag atggtgggat gactttatat ccttctttcc
     3361 aaggtggaaa aggataaggg tgaataaaaa tgggtttatt gattgcattg atcccggcag
     3421 ttgggtgggg gatccagcca ctgattttga aaaagattgg tggcagacca acaaatgaga
     3481 tattaggaac tggtattgga gccgtgctcg ttggcttact tgttcaatta ttcgcttctc
     3541 cagctggtat ttcagtgact acatttttga ttagtttact ttctggtgca ttctgggtca
     3601 tcggacaaac aggacagtat acatctttca acttgattgg tgtttctaaa acgatgccaa
     3661 tttcgactgc attacagtta gtcggaacct cattgattgg tgtcttcgct tttggagaat
     3721 ggtctggaag tatgggaaaa atcattggtg cagcagcaat cattcttctt gtatttggtt
     3781 ctgctttaac ggcaatcagt gatgatcctg gaaaaaaagg cggtatcaca aaaggaatca
     3841 gtctattagc atcaacaagt attggttatt gggtttacag tgcattgccc aaactagttg
     3901 atgcaagcgg actttccatt ttctttccgc aaatgatcgg tgtcttttta ggggcagtga
     3961 tttatgtgat tttccgaaaa ccaaccgcat tttctgaaga caagagttgg aaagcaacaa
     4021 tagttggagc catcttcagt gtgtcagcat tggcttatat tttttcagca aatgaaaatg
     4081 gggttgctac tgcatatatc attacacagc taaacgtagt tatctctaca ttaggcggta
     4141 tgtacatcct gcatgaaaat aagacaccaa aagaaaaaaa attaacgatt atcggattat
     4201 tgctgatcgt agtaggaagc atggtcacgg tctttatttg aggataaaga tggtaaaatc
     4261 tcatttatta aaaaaatatt tgtttgaacc aaacagtaag tacttataaa aaaatagcgc
     4321 tagaatttcc aacatctctg gaatttctag cgctttttaa ttgtttaaga tacaagtgaa
     4381 atatctgtct gcatcaataa tttttcattg atccattgac taaaatttac gacatgattg
     4441 aagttaccac cgattagtat ctccgcatga ttgtctttat aaagatcgta ttgtaaaaga
     4501 cggtcttttt tatttgcgta aacatcgtta tggtactgga ctaattgttc tcggatttga
     4561 ttgattgctg taaaatcacg atactgaagg ttgaaacgca tcgtgattgg tgcatttagc
     4621 atgaatcgct gcatttcttt tgctgcttcc tctgcttgat ctccgtatag gaactcaaaa
     4681 agattacgtt cagaaaattt ccattgcccg ccaacctttg ttccttttag ttttccttca
     4741 tgaagataat ttctgataga acgtgtagta acacctaatt gttcggctaa ttcatttact
     4801 gagtaaaaat ctttcaatgt tcaccctcct atgtgaatgg ttctactgac ttagttgata
     4861 tttgcttaat cacgaaatgt agaaagaacg attttaatta aggtcattgt aaaaatcaag
     4921 tcagaaaatt ctaacttttc tttctctaaa gaaattcgtt ctctcctaaa gtgatattat
     4981 atttaaatat acctgaaaat aatgggcagt attatgaaag atcactgata ttttctcgta
     5041 ttttttcctt attcaaaagt tttgcaggaa aattgctgaa aaaataattt tactaagtgg
     5101 aaaattcaaa gccattcaat cagtgatttt tttcagcaca agaaagactc cttataaaaa
     5161 tagcagatac tttgtcaatt aagtgtttaa ccagggatga taaaaaggat aggattgaac
     5221 aaaacctgta taagctgatg aatagtttcc tcgccagtaa aaggtttatt cgtataaagc
     5281 tttatcgcca aaatttatca tgaccttttt tatcttcaat attaaatgaa atcaattgtt
     5341 caatcaattc ccagttgatt acacttttcc aaggaacttt gatgacgtta tccgtatata
     5401 cgtagcctgc ttcttggata tttttttcaa gggcacgaat cgctgctttt tccggtgcga
     5461 tagaaaaatg atttttagca aaactaaatg caataataaa ggtaccatgg tcagtaaaca
     5521 taggttggtt ccattttaca gttgtgtcta gctggggata cgtttctgtt atcttagcaa
     5581 aaaggtcttt gatcttttgt tgatgttctt tttctttgat ctgattgatg atcggctgaa
     5641 atttttccat tctaaaacgc ctccattaag tggtttgatt tattttacca gaaaaacaat
     5701 agttatgtat aaaaaacgaa caaaacacaa gtaatgttgt aaccgctata tttatatgat
     5761 aagatgtctc aaataataaa atagaaaaga gacataaaaa tgattgactt ggcaaagaaa
     5821 ttcttacacg aaaatatata ttttgagttg tatcatcatc gagccattta tacaaatgaa
     5881 gatgctttgg taataaagaa agaacaagga tttacaggta cagagaccaa aagcttattc
     5941 ttaaaagata aaaaagataa taactacgta tatctgactt ttactacgaa acaaacggat
     6001 ttcaaagcat tagggaagat cgtcggtaaa aggctttcta ttgtttcatc agaacgcatg
     6061 gaagaacaaa cgggacaaaa gcagggcgct gtttctccgt ttggttatga aaaacagatt
     6121 ccgattatta ttgatgaaga gctcttatca aatgaaaaac ttgtttttgc accaggtaga
     6181 ccagatcaaa cgatggtcat ccaaacggtt gacttaaaca aaatcatcca gctacttgag
     6241 atgccgatat ttttgatgcc ggcaaacgaa aaaaacaatt aaccaagtaa aatagtgcat
     6301 acttggaggt gaagcaacat gataagttat ccattattag aaagaaatgc aacgattggg
     6361 gttactgcac catcctcagg cgtatcagag gaacaccatt cgttactcga atcagcttta
     6421 aagagaatgg aagaaaaatc tttccaagta gttactggaa agacgctttg gacgcaagat
     6481 aaggaaaaat caggtccagc aagaaaacga gcagatgaat tcaatcaaat gatgcaagat
     6541 gaaaatatcc aaatgatctt tccgccttgg ggaggagaat tattgattga gattctcgat
     6601 tttgtcgatt ttgatgctct acaaccaaaa tggatagtag gttattcaga tattagtacg
     6661 ttgctacttg ctgtcacatt aaaaacaggg atagccactg cacatggaac caaccttatt
     6721 gatttaagag gagagtactt ggatgaaacg acagcaatgt gggaaagtgt actgaaaaca
     6781 agagaaggag aatcgattct acagcaacct tctgaaaagt atcaaaaaga gtggccccat
     6841 gagcattcat catcttctgt tttccatctc actgaaccaa caaattggca atcagtcagc
     6901 ggagatgcag taaggatgaa gggacgatta ttaggtggct gtattgatac gatcagtcat
     6961 ttaatcggta ccccttatgg agatgtccaa tcttttaaaa gaaagtataa tgatggaaag
     7021 ccgatcttgt ggtttctaga aaattgtgag ctatcgtcag ttgatttaag aagatcactt
     7081 gttcagatga aactggcagg atggtttgat ggcagctcgg ggatcatgtt cggtagaagt
     7141 gcagcagagg atttgttaga ttataaaatg aaggatgtat atgaagatct gtcaaaggaa
     7201 ttaaaactac cgatcttgta tgatattgat tgtggtcatg taccgccaca actgacattg
     7261 atcaatggtg cctatgcaga agtagcggta gaagatagaa aagcgactgt tttgcaaacg
     7321 tttatttaaa aaattttttc ctgccttgga gtttatcaaa gaccaacaaa tctaaataga
     7381 aaagaaaatg aaagaagctg acagtatttt gccagcttct ttttgtatga tctattagaa
     7441 attttaatta tccataacta tcacattgat cagctgtttc acatcatttg gattacctgt
     7501 aggaatagct actacagatg cattatcaat aatttcttga gttgtttctc taatgaacgc
     7561 tggataagat gtttgatctg caggcatttg ccaatgtgaa ggaactggat aactagtgat
     7621 tgtcccgtca tggttacttg aatacactaa aactccctgg taactgtatt tcccagtgag
     7681 cataaccaca tctttcggat agactgcact ccctgcatca taaggggcga taggtgttcc
     7741 tgcaggataa tgaataacat gtagttcgaa atcacccgat gtatctctaa aagtattacc
     7801 tctaattgct agccaaacac gtgcgtactc aatttgtaga tcagaatatc ctgctaacgg
     7861 atctattgac tgagaagact gtgaggaagt tgtgtctatt gttgaagaag aaatatttgt
     7921 ctcaactgta ctactagatg tagaagaagt attgggctct gagactttac tgcttgttga
     7981 agatgtattc gtttcagtag aagctgattt ctgagtactt gatttttcag ctgaactggt
     8041 ttgtttgatt gaacttttgt ctgtggtcgc agatggatca ctattttctt tactaggaga
     8101 cgtacatcct acaaggaata aagagaccaa caataaaata aaacctaact ttttcatata
     8161 aaatacctca ttattttttt aataccagta tagcataatc ctgaattttt gaatccgtaa
     8221 aaccttgtc
//
LOCUS       DADVXM010000096         8069 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.101, whole genome shotgun sequence.
ACCESSION   DADVXM010000096 DADVXM010000000
VERSION     DADVXM010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.101"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(285..1061)
                     /locus_tag="KB927_002374"
     CDS             complement(285..1061)
                     /locus_tag="KB927_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBB6841264.1"
                     /translation="MIGFIYFIVIVLANTVGAVSGMGGGVLIKPIFDFIGAHSVAAIS
                     FYSTVAVFTMSLVSTARQLASGRKIHWQIVLWVSGGAVLGGILGNVAFDHLLLLFQNE
                     DEVQMIQIFLTVVTLLFAFFYTKYDWPGFQLKNNFWYCFCGLVLGFLASLLGIGGGPI
                     NVSLLMLMFALPIKEATVYSICTIFFSQLAKIVTIAGTTGFGLYDLKILWFVIPAAIV
                     GGLLGAKVSTVLSPQKVTLVFQTVIFLVLIINLYNGYQLL"
     gene            complement(1058..2170)
                     /locus_tag="KB927_002375"
     CDS             complement(1058..2170)
                     /locus_tag="KB927_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPASM domain-containing protein"
                     /protein_id="HBB6841265.1"
                     /translation="MKHISVLIKPASSLCNLRCSYCFYANVSSLREVRSFGKMKEEVT
                     EKMIENIYADLEDGDQLTLAFQGGEPTMAGLNYFRTVIRLVAQQQKQVQVHYAIQTNG
                     TMINEKWCAFLKEHDFLVGLSIDGHPLYHDLHRVDPKGRGTFQRVLQTKQLFDYYEID
                     YNVLCVLTNPLAKEAKKVFRFLKEQQIDFVQFIPCLDDLDAKKRNSYALTPKRFAGFY
                     HQLLQLWLQELAEGHYISIKLFDDLLNLLIKRQVTACGILGNCQVQYVIEADGSVYPC
                     DFYVLDEYRMGYIQEQTLRQLFEQDIAKTFLCGRPEMPKKCLSCPFQKMCRGGCKRMK
                     DAIYVDNTGYCGYQQLLQEFVPQINRILGLLQGVSV"
     gene            complement(2251..2955)
                     /locus_tag="KB927_002376"
     CDS             complement(2251..2955)
                     /locus_tag="KB927_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6841266.1"
                     /translation="MIKPKYLEIKQNLKQQIVTGQFHNGDRFYSESEIIKKYNVSSIT
                     AIRALKELVAEGYIVRYQGIGTFVSRARKEKIVKFSDIEIFSFDNDKTHVLSIKRENK
                     KQILDTLKLSTDSYYYQIERIREANEIPYIYHKSYLPEQYINSNYPEINYYNSIYKRL
                     KSDYNIDLNEENFRETNEILFPAPNSVCKQLKINESEPVVFQTKLSCLSENNKPIEYV
                     ESYKKWNFYKIQLLSN"
     gene            3075..4853
                     /locus_tag="KB927_002377"
     CDS             3075..4853
                     /locus_tag="KB927_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HBB6841267.1"
                     /translation="MTTFEIKEEFLLKGKTFKILSGAIHYFRIPPCDWEHSLYNLKAL
                     GFNTVETYVPWNLHEPQKGEFHFEGILDLERFLTIAQDLGLYAIVRPSPYICAEWEFG
                     GFPSWLLREPIHIRRNEIAYLEHVADYYDVLMKRIVPHQLNNGGNILMIQIENEYGSF
                     GEEKEYLRAIRDLMIKRGVTVPFFTSDGPWRATLRAGSMIEDDILVTGNFGSKAKDNF
                     NSMKQFFKEYDKNWPLMCMEFWDGWFNRWKEPIIQRDPQELAEAVKEVLEQGSINLYM
                     FHGGTNFGFMNGCSARGVIDLPQITSYDYGAPLDEQGNPTEKYYALRKMIHDNYPEIK
                     QLDPVIKPTIEKKKISLTNKVSLFATLDTISQPVQSKYPKTMEELGQNTGYLLYRTMI
                     ERDAEEERLRVIDGRDRSQLFLNQELQATQYQTEIGEDIQVSMTEEINQVDILIENMG
                     RVNYGHKLFAETQKKGIRTGVMADLHFITNWQQYSLPLENCKTVDYSKGWQPQHPSFY
                     RYEFLLEDIGDCFIDLRKFGKGIVFVNQTNIGRFWEVGPTLSLYISSGFLKVGKNEIV
                     IFETEGTYEPEINLLKAPLYKEMKEG"
     gene            4857..5336
                     /locus_tag="KB927_002378"
     CDS             4857..5336
                     /locus_tag="KB927_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HBB6841268.1"
                     /translation="MSIIGVRIDGRLIHGQVANLWTTKLNISRIMVVDDEVAQNDIEK
                     SGLKLATPAGVKLSILPIEKAAQNILAGKYDSQRLLIIARKPDRLLKLVELGVPIKEI
                     NVGNMSQTSETRSITKSINVVDQDVETFNQLNEKGVHLIAQMVPSDKADDFMSLLNK"
     gene            5359..5766
                     /locus_tag="KB927_002379"
     CDS             5359..5766
                     /locus_tag="KB927_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6841269.1"
                     /translation="MAGHLVLISHGRFCEELKRSVDMIMGVQKDIYTVGLLPEESAKD
                     FRVNFEKTINGLKKVTVLADLMGGTPCNVVSQLILEGKEIELYAGMNMPMVIGFVNNQ
                     FLGEDSSLVNKGRENIIHVNEYLEVNPIDLEDE"
     gene            6017..6334
                     /locus_tag="KB927_002380"
     CDS             6017..6334
                     /locus_tag="KB927_002380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841270.1"
                     /translation="MVFEDQYLQIKNSENIEACIEISNSQESNIFVSPENGPVKPNFN
                     YLTYDRFSQNTVFDGYKLEQSSPAIHSGKKVIDKNGYNLGTDFFGIKLDGILDIGAVK
                     SSK"
     gene            6356..7168
                     /locus_tag="KB927_002381"
     CDS             6356..7168
                     /locus_tag="KB927_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6841271.1"
                     /translation="MNDISFFQIFSLICLAILGGIDPYLSGLQLSKPAISGFLAGIIM
                     GDINTGLLVGATLQLMVLGVGTFGGSSIPDFGTGAIIGTALGVVSGKGIEFAIGISVP
                     VGLLLVQLDILARFCGVYFLHRVDKHIEEENFHKISLEAWLSLVPIALSRAIPVGLCL
                     IFGNEVVNTVLNYAPDWLMGGLKLAGAILPVVGIAILLHYLPIRNFFGFLIIGYILAA
                     YLNIPMMGISFAGLAAAIIHYKKLQDKRLLESKLDTINHIEVVNGEVDDDEI"
     gene            7155..7970
                     /locus_tag="KB927_002382"
     CDS             7155..7970
                     /locus_tag="KB927_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6841272.1"
                     /translation="MMKSNVSKLSSKDLRKVSLRYMFGAQLGWNYERMMNVAYVRAVY
                     PALKKLYKDEKELKSVLQSEMQFYNTSPFLSAFIIGIDLALQVEDGSKSKDAVAAIKT
                     SMMGPFAAVGDSLFGAVIPTIFGSLAAYMGLEGNPLGVLLWLLVSLIILFLRYFELPI
                     AFREGKKLVSSVGGLLKDLTESATLLGVVVIGGLVPSVVKVGVPFKLVIGDKKLSFQT
                     EMLDPIMPAIVPVVLVLLAYWLLSKKSLNSTKVIWIFLVLSILMYSLNILAVL"
BASE COUNT         2686 a         1204 c         1594 g         2585 t
ORIGIN      
        1 aaaatctgag ccagaatgtg gttcattctg acccagattt gattttgcac aactcatcag
       61 tccttattga caaagagcct attttgttag tagatgtctg gaaacggtac tttgcacatg
      121 gtgaacaggc agtgctatta gaaaaatcat gcatattact aatgcaattg agagtattta
      181 ttctagtttc agaaaagtca caaaaaagag cgcttcttaa tgagaaagta cttctaaagt
      241 tactaattaa tcgttttcta taagtggttg ataatactcg ttttttatag taattgatag
      301 ccgttataaa gattgatgat tagcaccaag aagatgactg tctggaagac cagcgtcact
      361 ttttgtggtg agaggacagt gctgactttt gcccctaaca aaccgccaac aatcgcggct
      421 ggaatcacaa accacaaaat ctttaagtca tagaggccaa atccagtggt cccagcaatc
      481 gtcacgattt tcgccaattg agagaaaaaa atcgtacaaa tcgaatagac cgtggcttct
      541 ttgatgggta aagcaaacat cagcatcagc aaggacacat tgatcggtcc accgccaatg
      601 cccagcagac tcgctagaaa accaaggact aggccacaga agcaatacca gaagttattt
      661 ttcagttgga atccgggcca gtcgtatttg gtataaaaga aagcaaacag cagtgtcaca
      721 acggtcaaaa agatctgaat catttgtacc tcatcttcat tctgaaataa aagcagcagg
      781 tgatcaaaag cgacattgcc caagatgcct cctaagacgg cgccgcctga aacccaaagg
      841 acgatttgcc aatggatttt acgtccacta gccaactgtc ttgcggtcga aaccagcgac
      901 atggtaaaca cggctacggt agaataaaac gagatggctg caacagaatg ggcaccgata
      961 aaatcaaaaa tgggtttgat cagaacaccg ccccccatgc ctgaaacggc accaaccgta
     1021 ttcgccaaca cgatcactat aaaataaatg aacccaatca cacacttacc ccctgtaaca
     1081 aacctaaaat ccgattaatc tgcggtacaa attcctgcaa aagttgctga taaccacaat
     1141 agcctgtgtt atctacatag atggcatctt tcatccgttt gcagccgcca cgacacattt
     1201 tttgaaacgg gcaactcaga catttctttg gcatttcggg gcgtccacac aaaaacgttt
     1261 ttgcaatgtc ctgttcaaat aactgacgta aagtctgttc ttgaatatac cccatgcgat
     1321 actcatccag cacataaaaa tcacaaggat acacactgcc atctgcttca atgacatatt
     1381 gtacctgaca gtttcctaaa atcccgcagg cagtgacttg tcgcttgatc aatagattca
     1441 aaagatcatc aaaaagcttg atacttatat aatgcccctc cgctaattct tgcagccata
     1501 actgcaaaag ctggtggtaa aatcctgcaa aacgttttgg tgtgagagca taactatttc
     1561 ttttttttgc atctagatca tctaaacaag gaataaactg gacaaaatca atttgttgct
     1621 cttttagaaa gcgaaagact ttcttagcct cttttgccaa cggattggtc aagacacaaa
     1681 gtacattgta gtcgatctca tagtagtcaa acagctgttt tgtttgcagc actcgctgaa
     1741 aagttcctct tcctttcgga tcgacccgat gcagatcatg gtagagcgga tggccatcga
     1801 tcgagagacc gaccaaaaaa tcatgttctt tcaaaaaagc acaccatttt tcattgatca
     1861 tggtcccatt cgtttgaatc gcataatgga cctgtacctg cttttgttgt tgcgctacta
     1921 accggatcac tgtacgaaaa taattgaggc ccgccatcgt tggctctcca ccttgaaacg
     1981 ctaatgttaa ttgatcgccg tcttctaagt ctgcataaat attttcgatc attttctctg
     2041 tcacttcttc tttcattttg ccaaacgagc ggacttctcg caaggaactg acattggcat
     2101 aaaagcagta gctgcagcga agattgcaga gggaagatgc gggtttgatc aatactgaaa
     2161 tatgtttcat agtaagaacc tcatttttta acatagttta attatgaaaa attgctataa
     2221 cgaacaaagt aaaatcaaat tcagtagtag ttaattagat aggagttgaa tcttatagaa
     2281 attccatttt ttataacttt caacatattc tataggttta ttattttcag ataagcagga
     2341 taatttggtt tgaaaaacga caggctcaga ttcatttatt tttagttgtt tacatacact
     2401 attaggagca ggaaataaaa tttcgtttgt ttccctaaag ttttcttcgt ttaaatcaat
     2461 gttgtagtct gattttaaac gtttgtaaat agaattgtaa taattaattt ctggataatt
     2521 agaatttata tattgttctg gcaaataaga tttatgatag atataaggta tttcattagc
     2581 ttctctaatt cgttcgattt gataataata tgaatcagtt gataatttta atgtatctaa
     2641 tatttgtttt ttattttcgc gtttaatcga aagaacgtgt gttttatcat tgtcaaatga
     2701 aaatatttct atatcagaaa attttactat tttttctttt cttgcacgtg aaacgaaagt
     2761 tcctattcct tgataacgta cgatataccc ctcggcaact aattctttta acgcacgaat
     2821 tgctgttata gaactaacat tatatttttt gataatttct gattctgaat agaatcggtc
     2881 gccattatga aattgaccgg ttacaatttg ttgttttaga ttctgtttga tttctagata
     2941 tttcggtttt attataagct ccccctttaa attactcgca tctatattaa catacttaaa
     3001 aaaaaattgt tgacttttaa tacaaaagca ttaatatact aagtatatta acacattgag
     3061 gtgaaaagta acagatgact acatttgaaa taaaggaaga atttttatta aagggaaaaa
     3121 catttaaaat actatctggt gcaattcatt attttcggat tcccccatgt gattgggaac
     3181 attctttgta caatttaaaa gcactaggat ttaatacagt agagacatat gttccttgga
     3241 atttacatga gcctcaaaaa ggagagtttc attttgaagg gatattggat ttagagagat
     3301 ttttgacaat cgctcaagac ttaggattat atgctattgt gcggccatcg ccttatattt
     3361 gtgctgaatg ggaatttgga gggtttccgt catggctact ccgtgaaccg attcatatcc
     3421 gaaggaatga aatcgcttat ttggagcatg tagcggatta ttatgatgtt ttgatgaaaa
     3481 ggattgttcc ccatcaactt aataatgggg gaaatatatt gatgattcaa attgaaaatg
     3541 agtatggatc ttttggggaa gaaaaggaat atttgcgtgc gataagagat ttgatgatta
     3601 agcgaggagt gacagttcct tttttcactt cagatggacc gtggagggct actttacgag
     3661 cgggaagcat gattgaagat gatattttgg ttactggtaa ttttggttct aaagcaaaag
     3721 acaacttcaa ctctatgaag cagtttttta aagaatatga taaaaattgg ccactgatgt
     3781 gtatggaatt ttgggatggt tggtttaatc gttggaaaga accaattatt caacgagatc
     3841 cacaggaact cgctgaagcg gtaaaagagg tattagaaca aggaagcatt aatttatata
     3901 tgtttcatgg aggaacgaat tttgggttta tgaatggttg ttcagcaaga ggagtgattg
     3961 atttaccgca aattacttcc tatgattatg gtgcaccatt agatgagcag gggaatccaa
     4021 cagaaaaata ttatgcattg cggaaaatga ttcatgataa ttatccagag attaagcagc
     4081 tagatcctgt cattaaaccc acgattgaaa agaaaaagat ttctttgacg aataaggtaa
     4141 gtcttttcgc gactttagat accattagtc aaccggttca atcaaagtat ccaaagacaa
     4201 tggaagagtt gggacaaaat acaggttatc tactttaccg aacaatgata gagagggatg
     4261 cagaggaaga acgattacgg gtaattgatg gcagagatcg cagccaatta tttttgaatc
     4321 aagaattaca agctacccaa tatcaaacag aaataggtga agatatacaa gttagtatga
     4381 cagaagaaat caatcaagtg gatattttga ttgaaaatat gggacgtgtc aattatggac
     4441 ataaactctt tgcggaaacg caaaaaaaag gaattagaac gggagtaatg gcagacttac
     4501 attttattac aaattggcaa cagtattcat tgcctttgga aaattgtaaa actgtggatt
     4561 attcaaaagg atggcagccc caacacccaa gtttttatcg atatgagttt cttttagagg
     4621 atatcggtga ttgttttatt gatttaagga aatttggtaa aggaattgtc tttgttaatc
     4681 agaccaatat aggtcgtttt tgggaagtag gtccaacgct ttcactgtac atctctagcg
     4741 gctttctaaa agttggtaag aatgaaattg ttatttttga gacagaaggt acctatgaac
     4801 cagaaatcaa tttattaaaa gcaccattat ataaagaaat gaaagaggga tgaacaatga
     4861 gtattattgg agtaagaatt gatggacgtt taattcacgg acaggtagct aatttatgga
     4921 caaccaaatt gaatatttct cgaattatgg ttgtggatga tgaagtggct caaaatgata
     4981 ttgaaaaaag cggattgaaa ttggctaccc cagcaggggt gaaactaagt attttgccga
     5041 ttgaaaaagc ggcgcaaaac attttagcag gaaaatatga ttcacaacgt ttactgatta
     5101 ttgcacgaaa acctgatcga ttattaaaat tggtagaatt gggcgttcca ataaaagaga
     5161 ttaatgttgg aaatatgtca caaacttctg agactcgatc aattacgaaa tcaattaatg
     5221 ttgtcgatca agatgtagaa acgttcaatc aattaaatga aaaaggtgtc catttaattg
     5281 cgcaaatggt tccaagtgac aaagcagatg actttatgtc tctgttaaat aaataataat
     5341 atacgaggag gtgaaaagat ggcggggcat ttagttttaa ttagtcatgg acgattttgt
     5401 gaagagttaa agagaagtgt tgatatgatc atgggagtac aaaaagatat ttatactgta
     5461 gggttattac ctgaagagtc agcaaaagat tttcgagtaa atttcgaaaa aacaattaat
     5521 ggtttgaaaa aagttacagt tctggctgat ctaatgggag gcactccttg caatgttgtt
     5581 tctcaattaa ttttagaagg aaaagaaata gaactatatg caggaatgaa tatgccaatg
     5641 gttataggct ttgttaataa tcaattttta ggagaagata gttctttggt aaataaagga
     5701 agagaaaata ttatacatgt aaatgaatat ttggaagtaa atccaataga tttagaagat
     5761 gaatgaatgt ggaggaattt atgaatataa aaaaatccaa atatatttta ttgcaacttg
     5821 ctgtttgatc agtttatcta tgttaacaaa agtcgctcat gctgaaagta accccattgg
     5881 taattgttac tatgttagtt cgcaaagagg gagtgacact aattcaggat tatctatatc
     5941 tgagtctttt aaaagtttaa ataaaataaa tgaacttaaa taaaatccag gggataaagt
     6001 tttattagaa aatggattgg tttttgaaga tcagtattta caaataaaaa attcagaaaa
     6061 tatagaggcg tgtattgaaa tcagtaatag ccaagagtcg aatatatttg tttctcctga
     6121 aaatggtccc gtaaaaccta attttaacta tttgacatat gatcgattca gtcagaatac
     6181 agtgtttgat ggatataaat tggaacaatc atctcctgct attcatagtg ggaagaaggt
     6241 tatcgataaa aatggttata atttaggaac tgattttttt ggtattaagt tagatggcat
     6301 actagatatt ggggcagtga aaagttcaaa ataatataaa ggagttagtt tgatcatgaa
     6361 tgatatttct ttttttcaga tattttcttt aatatgttta gctatactag gaggtataga
     6421 tccttatctg tcaggattac aattaagtaa accggcaatt tctggttttc tagcaggaat
     6481 tataatggga gatattaata caggcttatt agtaggagca acattacaac tgatggtctt
     6541 aggtgtagga acatttggtg gctcatcaat tcctgatttt ggcacagggg caatcattgg
     6601 tacagcatta ggtgttgtta gtggaaaagg aattgaattt gcaataggta tttctgttcc
     6661 tgtaggctta ttattagttc aattagatat tttagctcgt ttttgtgggg tttatttttt
     6721 acatcgtgtg gataaacata tagaagaaga aaattttcat aagattagtt tagaagcatg
     6781 gttaagttta gttcctattg cattatctcg tgcaatacca gtaggtttat gtttaatttt
     6841 tggtaatgaa gtagtaaata cagtattaaa ttatgcaccg gattggttaa tgggaggatt
     6901 aaaattggca ggagctatat taccagttgt tgggattgcc attttactac attatttgcc
     6961 aattaggaat tttttcggtt ttttaattat tgggtatatt ttagccgctt atttaaatat
     7021 tccaatgatg ggtatttctt ttgcaggatt ggcagctgct attattcact ataaaaaatt
     7081 acaagataaa cgtttattag aatcaaaact agatactatc aatcatatag aagtagttaa
     7141 cggagaggtt gatgatgatg aaatctaatg ttagcaaatt aagtagcaaa gatctgagaa
     7201 aagttagttt aagatatatg tttggagctc aactaggttg gaactacgaa cgaatgatga
     7261 atgtggcata tgttcgagct gtatatccag ctttgaaaaa gttatacaaa gatgaaaaag
     7321 aattaaaaag tgtgttgcaa tcagaaatgc aattctataa taccagtcct tttttaagtg
     7381 catttattat tggaattgat ttagcattgc aagtagaaga tggaagcaaa tcgaaagatg
     7441 ctgttgcagc aattaaaacg agtatgatgg gaccttttgc agctgtaggc gattctttat
     7501 ttggggcagt gattccaaca atttttggat ctctagcagc ttatatggga ttagaaggaa
     7561 atccattagg tgtactactt tggttattag tatctctcat tatactattt ttgagatatt
     7621 ttgagttacc aattgctttc cgagaaggta aaaaactggt atccagtgta ggtggattgt
     7681 tgaaggattt aactgaatca gcaactttac ttggcgtagt agtaatagga ggcttggttc
     7741 ctagtgttgt aaaggttggt gttccattca agttagttat tggtgataag aaactatctt
     7801 tccaaacaga aatgttagac cctattatgc cagctatagt acctgttgtt ttagttttat
     7861 tggcatattg gttattaagc aaaaaatctc tcaattcaac caaagttatt tggatatttt
     7921 tagttttgtc aatactaatg tattcattaa atattttagc agttttgtaa tagatgtggg
     7981 ggcgtgatca actaatttat ggcatgtccc ctgtttaatt ttctaaatat tatattttta
     8041 aatgagtgga aagaagatat tagagattt
//
LOCUS       DADVXM010000097         8069 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.102, whole genome shotgun sequence.
ACCESSION   DADVXM010000097 DADVXM010000000
VERSION     DADVXM010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.102"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            386..574
                     /locus_tag="KB927_002383"
     CDS             386..574
                     /locus_tag="KB927_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBB6841273.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            652..1665
                     /locus_tag="KB927_002384"
     CDS             652..1665
                     /locus_tag="KB927_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6841274.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(1732..2766)
                     /locus_tag="KB927_002385"
     CDS             complement(1732..2766)
                     /locus_tag="KB927_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6841275.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            2881..5106
                     /locus_tag="KB927_002386"
     CDS             2881..5106
                     /locus_tag="KB927_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6841276.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            5124..7007
                     /locus_tag="KB927_002387"
     CDS             5124..7007
                     /locus_tag="KB927_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBB6841277.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            6988..7962
                     /locus_tag="KB927_002388"
     CDS             6988..7962
                     /locus_tag="KB927_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBB6841278.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
BASE COUNT         2604 a         1470 c         1707 g         2288 t
ORIGIN      
        1 tttagttagt ctacattatt ttggcgattt gccaataagg actgttgagt tgtgcaaaat
       61 caaatctggg tcagaatgaa cgtcattctg tctcagattt ttcgttattt caatttgatt
      121 aactgattga tcaaaaagat ttttattttc atattctcaa atgattcaac actaaatata
      181 catgtttgac gcggaaatta ttattcgatt ttggcggcat caggggggat gacgacgtag
      241 cagacccatt attttactca agaaaatgtc cgtgcctatt atttagaata cgatagtgaa
      301 cgtgctggga gttttgttct tttagagaaa gtctctgaag ataaattagt tgtcttagat
      361 tttgactgta acgaaaaatg gcgaaatgga agagcaccag caagtgattg accggatcta
      421 cgaagcgaca cgatatctgc ctttggatcg tttgtgctta agtcctcaat gtggatttgc
      481 ttcaacagaa gaagaaaatg ttttgtttga agaacaatgg aaaaaatttc ttttgtcaaa
      541 agcattgcag aagaagtttg gggaaaatca ttaaatcatc taggagagct tgataggaaa
      601 taacactatg gtataatcag aatgcttaat actaactact gagggagcct tatgaaaaag
      661 aaaattctta aatttatcgg atggttcttc ggaatcattc ttgggatcgc gtttgcaatc
      721 tttcttgcct tccagctttc ccccagacct ggagcattct tgatcaacca tatgttttca
      781 aatactgttc aaatcactga taaaaaaacg ttcgatcaag cagaaaaaaa cgtggcgaaa
      841 aaaacagatt tgacgtatga gtccaagtat aaagagaata cttatgacat ctactatcca
      901 aaaaacagca aggggcctgt tcctgttcta ttttgggtac atggtggagg attcgtcggc
      961 ggagataaat cgggtgtcaa agaatttgcg acaaaattag tttcagacgc caacatcgca
     1021 gtggttgcga tgaattatga attagcgcct gattcagaat accctaatca agttcttcaa
     1081 gtgaatgaac tgatcaaaga tttattagct gaagaaaaag acgacaaatt gctagacatg
     1141 gaacaattat tttttggtgg agatagtgca ggttcacaaa tcgcattgca atatgcagct
     1201 atacaaacga atgatgcgta tgctaaacaa atgaaaatca aacagctact tccaaaagat
     1261 agtctgaaag gaaccatttc ttattgcgga cctgttgatt tgaagctaac agcacagcag
     1321 cattcggatg atcgatttat gaagtttttc gtcaaaaccg ttgcgtggtc gttgattgga
     1381 acaaaagatt ggaaaacgag tgagcaattg aaagaagcta gtgtggctga ccatgtttct
     1441 aaggaatttc cgccaacgta tataactgac ggaaatgcat actcattcca ggagcaaggt
     1501 caagcattag aaaatcggtt gacagaatta aaggtacccg tgcaatcctt gttttataca
     1561 gatacaaaaa aagagattac ccatgaatac caatttgatt acacgctaaa agaatcgcaa
     1621 aattgttacc agcagacatt ggattttgtg aataagtata agtaagaggt tgtgaaaaag
     1681 ccgtttcgtt ttgagtatga agaaacgaag cggcttttca caacctctct ttcaatacct
     1741 ttttgttctt gggataaaac tttccctaac aatcaatcgt gcaggataag tcaaaatgat
     1801 tggttcgtcc cgtataccgt caattcgctc caatgccatt cgaacagctg cttgcccaat
     1861 tgatttcgca ttgatttgaa cactggtcaa gccaggggag aggtttgcga ttgtctcgat
     1921 attatcaaag cttgctacaa caatctcttc tccaatttgg atattttttt gtttcaatgc
     1981 ccgatagaca ccaattgcca ttggatcgct cccgacaaga atggcagtag gaagagggga
     2041 ttcattttct aatagattag tcgcaagtac ctcaccttgt ttttctgtcc agccacctag
     2101 atgataagac atatattttt ctaagtgatg atcgatcata aaatgctgat aggcacgcat
     2161 cctcttttca tttatagaaa tctgcttccc accgaattca tccatatcga ctttatatcc
     2221 cccgatatag gctattcttt tatgaccatt ttctaagaac aattccagta cggttttagt
     2281 catccgttca agatctgcat acaccatatc gacctcttgc tggatgtcag ggttatccac
     2341 gacgactatt tgcatgtttt gttttaacaa ggcggtaatc gattctttcg taacagtccc
     2401 aacaacgatc accgcaccta actgatctag atcttcccat tgtttaggat tatcagatag
     2461 attatagatt cgattcatcc ctaaatgcag acgtcgagct tcttcttcca tccctactcg
     2521 caaatgtttg taatagatat cctgttcttc gctcgctttg ccgatcgtag agatcacacc
     2581 aatcgaaggc attctctttt tgatatattt acgagtactg atgtcataat ccaacgcagc
     2641 agctgcctct actatccgtt gccgagtagt ctgagccaca tggatcgtct gatcgttatt
     2701 caacacacgg gaaactgtag caggagagac atttgccttt cgtgcgacat ctctaattcc
     2761 aaccattttt acacactcct caaaaaaata aaaaattttt attgacaaaa ttgtttagta
     2821 aacagtatac aggaattata aaaaaaagta aacggtttcc gttttgttgg gagtgaaatg
     2881 atggatatta cgcatagaaa aacagataaa aatttcatct tatttgatga aaagagccga
     2941 gtcttccatt tacgaaatac atttctttct tatctgataa agatagaaga aagcaatgta
     3001 ttggcgcata tttattttgg caaaccagtc aagcagtaca aagacaataa aaattatccc
     3061 cgaagagatc gtggattttc aggaaatgtt cccttaaatc ctgaccggtc tctgtcgaaa
     3121 gatacactac cgcaagaata ctcttctcat ggcagcatgg actttcgaac gcccgcatcg
     3181 atcattcagc gcaagaatgg atcagactta ctggatctga gatatgacag ccattatatt
     3241 acagatggga agccagagat cgaaggcttg cctcaaactt atgtgatgga caagtcagag
     3301 gcacaaacgt tggtgatttc acttaaggat agagaaacag cgatttattt cgatttgttc
     3361 tataccatat ttactgatag agcagtgatc acacgatctg taaagataag aaatgaaacc
     3421 ggagaaacaa tcaaactaga aaaagcggct agtttccagc tagactttgc ccatactagg
     3481 cgatttgatg aagtcattgc tttgccagga gcacatgtca atgaaagaca gatttcacgg
     3541 caatctgttt tatctggaac aaaagtattt gaaagccgtc gaggaacgag cagtcaccat
     3601 atgaataact ttattgcttt agttcatcat catacgacag aaaatactgg agaagcgatc
     3661 ggacttcaat ttgtttattc cggcaaccat tctttcgaac ttgaaaaaga tcagatcaat
     3721 caattgagag tcgtcggtgg gatcaacagc catcgttttt cgtgggaatt gaatgcaggc
     3781 cagtcttttc aaacacctga aatgatcctt tcttactcaa gtcagggatt gaacaaaatg
     3841 agtcagatcc accatgagtt gctacgtgaa agaatcgcaa gaggtcgtca tcaatttgct
     3901 gaacggccga ttctggtcaa taactgggaa gccacttact ttgacttcaa tagtgaaaaa
     3961 atcaaggcga tcattgatga agcaaaggag ctaggcatcg aaatgttcgt attagatgat
     4021 ggctggtttg gaaaaagaga tgcggacaat tcttcattag gagactggtt cgagtatgaa
     4081 ggcaagttga caaatggatt acgtgaaata gcagattatg ctcatagcaa aggattgaaa
     4141 tttggtttat ggtttgaacc tgaaatgatc tcggttgatt ctgaactgta tcgaacacat
     4201 cctgattttc ttatgcagga gccaggtaga atgccttctg cttccagatc acaacatgta
     4261 ctggatttta caaggttaga tgttcggcag acgattgaga aacaaatgag aaagatttta
     4321 gatacgattc ctcttgacta catcaaatgg gatatgaacc gttcgctttc agatgtctat
     4381 tcgattaccc ttgacccaca gagacaagga gaagtagcgc atcgttatat gctcgggctt
     4441 tatgaactac ttgaacattt gacaactgat tatccggaaa tcttatggga aggctgttct
     4501 ggtggaggtg gacggtttga tgccgggttt atttattata tgccgcagtc atggacaagt
     4561 gataacacgg atgcagtgga gcgtatgaaa atccaatatg gaacaagcct tgcttatccg
     4621 atttcgtcca tcacagctca tgtatcagct gtaccaaatc atcagaccga cagatctact
     4681 tcgttgaaaa caagaggaga aacagctatg agcgctgttt ttggttatga actggatttg
     4741 acaaagctgt ctcctgaaga aaaaaagcaa gtaaaagacc aaattatatc ctatcaaacg
     4801 attcgtccgg tgatccagta tggccattat tatcgtttgg cgagtccttt tgaagaaaat
     4861 attgccgcat ggatgtttgt gtctcctaaa caagatgaag ctattgtgtt tttagggagg
     4921 atactagctt cagctcaacc agcgttccat gaagtatatc tgatggggtt agatgatgag
     4981 gcactttatc aggaacagac ctcgaagcgg atattttcgg gggccgaatt gatgacagtt
     5041 ggactttact tccccgattt tcaaggtgat ttccaaacag aactgcttca tttcaaaaag
     5101 ttatgagaga gaaggaaaaa agtatgaaag caaatataaa atggttagat gatccacaag
     5161 tttttagagt gaaccaatca aatgcacata gcgatcatgt ttgttatgca acaagggaag
     5221 aagtagaaac cacatcctcc cttaaacagt ctttaaatgg atcatggcgt ttttgttatt
     5281 cgccaaatcc ttcggtacga ccaaaaacat tttataaaaa agattttgat gcctgttctt
     5341 ttgatgaaat cactgttcct agtcatattg aattagcaaa ttatgacaag atccattaca
     5401 tcaatacgat gtatccgtgg gagggacatg tatttcgccg tccccctttc acgacaagcc
     5461 ctgagaaaga ggcggaaggg atcttttcag ctgctaaaga caatccggtt ggttcgtatt
     5521 tgacgacttt tcgattagaa gaaggtctaa agggaaaaca aatctcgatt cattttgctg
     5581 gtgtagaaca agcaatgttt atttggttga atggtcattt tatcgggtat gccgaagatt
     5641 cgttcactcc gtctgaattt gatttaacac cttatttgga agaagaaaat attctagctg
     5701 tggaggttta caaaagaagt acagctgcat tcttggaaga tcaggacttt ttccgatttt
     5761 ttgggatctt cagagatgtc ttcttagttg ctcgaggaca aaaccattta gaagatcttt
     5821 ggatcaaacc tcgcttagat gacaaatgtc aaaatggcaa acttgaagta gatttgtctt
     5881 ttgagcaagt agccaaaaac agtcagctga atgtagcgat actagatcct gatgggaagg
     5941 aaatctatca acagcaatat ccgttaaaag agcaaatgac gattcgcatc gatggatttg
     6001 aaaatgtggc actgtggggg cattttcagc ccaatttata taagcttgaa ttggagacga
     6061 tagacgaaga aaaaagagta acggagtata ttgactattc cttcggtttt cgtaaaatcg
     6121 aaatcaaaga taaaatcatc tacttcaatg gaaaacggat gattatcaac ggggtaaatc
     6181 gacatgagtg gcatccgaaa aaaggacgcg ccatcactat agaagatatg gaaaaagatt
     6241 tggctatcat aaaaaatgca aagatcaacg gcgtacggac atctcattac cccaaccaga
     6301 tcacttggta ttatttatgc gaccaagcag gaatccatgt gatggcggaa acgaacctcg
     6361 aatcccatgg ctcatggcaa aaaatgggcg catttgagcc ttcttacaac gtaccaggtg
     6421 cagtacctca gtggcaggcg gctgttcttg atcgagcaaa aacgaatttc gaaacattaa
     6481 aaaaccatcc aagtattctt ttttggtctc ttggaaatga atcttatgcg gaagaaaaca
     6541 ttcgacaaat gaacgattac ttcaaaaaag tagaccccga tcgacttgtc cattatgaag
     6601 ggaattttcc aaatccagca ttcgaagatt cgatttcaga tgtaaaaagc tgcatgtatg
     6661 cgccaccaga agagatcatt gactaccttg aaaataaagc ggaaaaaccg ttcatcttat
     6721 gtgaatatat gcatgacatg gggaattcgt taggtggaat ggattcttac atgacgttgc
     6781 ttgatcgtta tgaaatgtac caaggaggct atatatggga ttttaaagat caggcgatcc
     6841 aagtgactga tccaatcaca ggcagagaag tgatgcgcta tggcggtgac tttgacgata
     6901 aaccaagtga ctatgaattc tcagggaatg ggatcgtttt tgcagatgga caagaaaaac
     6961 ccgccatgca ggaggtaaga tattattatg aaaaatacag taaataaaag tcatatggat
     7021 acggaaaaag ttgcaatcgt cttcggcgac tgtacattag gtgtcaaatc ggggaatacg
     7081 cattatattt tttcttatac aagaggcgga ctggaatcgc tcaataaaaa cggaaaagaa
     7141 tggctatacc gggaaacact tccagttttt tggcgagcaa cgaccgataa tgacagaggt
     7201 agcggatttg gatttaaatc cggtatgtgg ttaggagccg gattgtatcc aaaagtcaaa
     7261 gaaatagaag tactggtgga caataaaaag atcgatttgc cgattgctcc agtaaataat
     7321 caatattcaa gtaatgaata cgctgaaacg gttgaaatca tttttacact ggaaatcaac
     7381 acagtaccaa aaacccaagt gacaatttcc taccaaatcg ctggagaggg taaaatgctt
     7441 gtcaatatgc attattatgg acaaaaagga ttaccggaat tacccgcatt gggtttaagg
     7501 ttcattatgc caacgaaagc aaaatttttt gagtatgaag gcctatcagg ggaaacatat
     7561 ccggatcgga tggctggtgg tgtcgaaggt atttataaag tggcaggact ccccgtttcc
     7621 ccataccttg ttccccaaga atgcggcatg catatggaaa cgaaatgggt agaactaaca
     7681 agaaatcaaa cgttggataa tacggataaa gatcaagaag atttttcgtt gcgatttgaa
     7741 cagcaggata cgccatttgc tttttccgct ttaccattca aagcagaaga actggaacag
     7801 gcaacacata tagaagaact accgccagaa agacgaacgg ttcttacgat ttttgcaaaa
     7861 gtaagaggag tcgggggtat caatagctgg ggagcggatg ttgagtcacc ttaccgaatc
     7921 agcagcgaag aggaccatga aatcggcttt attattcagt agcaatcttt agattattat
     7981 ttgaaaaacg gagtttacaa gacaaagctg ctttattcta tatgtcatga acaagagagt
     8041 aaaaaagttc tcagatactt ttgttcatg
//
LOCUS       DADVXM010000098         7904 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.104, whole genome shotgun sequence.
ACCESSION   DADVXM010000098 DADVXM010000000
VERSION     DADVXM010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.104"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            709..1602
                     /locus_tag="KB927_002389"
     CDS             709..1602
                     /locus_tag="KB927_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6841279.1"
                     /translation="MGKISLGIDIGGTFIKYALIDKQHRIKEKWKVETVKYNTADEFY
                     DYICSNIRNVDEIDKIGVSAPGLIDEDSNVKSYAAPNVAIMYGTNINNEINKRTNKKV
                     SAINDAKAAGLCEFKIGNAKGYKSSAFLIIGTGTGGCICDENGVVYGKDSFAGEFHNM
                     PFVNAEIGGLDKMGDYASITGLVNLYNKKANREEQVQYGNEVCKKYLNGNESAVSSVD
                     EWIGNIVAQLIVITVFYNPEVICIGGGISEENWFINKVRETYKKTCREYLEADFITTE
                     INRCKHNNDANILGAVIKASI"
     gene            1676..3115
                     /locus_tag="KB927_002390"
     CDS             1676..3115
                     /locus_tag="KB927_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6841280.1"
                     /translation="MIYEELDKFQDDFLWGSASAAYQVEGAWDKDGKGESVWDVYTRQ
                     PGTTFKNTNGNIAVDHYNRYKEDVALMAEMGLKAYRFSIAWTRIYPNGRNEVNEEGLK
                     FYENLIDELIANNIQPIITLYHWDLPQHLQDLYGGWESREIIHDFNEYCVTLFKRFGN
                     KVKHWVSLNEQNIFVTLGYVTAMHPPAVKDQKRMLEANHIANLANATVIESFKKYVPD
                     GMIGPSFAFGPVYPFSCDPKDVLSAENAEDLNCNWWLDVYCKGKYPVFAFKYYERLGI
                     APTIEDGDLELLERVKPDFIGINYYQTSTVAFNPLDGVGQSEGINNTGKKGTTKESGL
                     PGVYKNAKNAHLETTNWDWAIDPTGLRIGLRRLTSKYNLPILITENGLGEFDKLEEDD
                     TVNDAHRIDYLSAHIKACKEAITDGVDLLGYCTWSFTDLLSWLNGYQKRYGFVYVDRD
                     ENDQKDLRRIKKNSFYWYKNVIRTNGEEL"
     gene            3163..3465
                     /locus_tag="KB927_002391"
     CDS             3163..3465
                     /locus_tag="KB927_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6841281.1"
                     /translation="MKKILLVCSAGMSTSLLVTKMRNSAKEKGIEVEIDALPVAEAST
                     AVDNVDIVLLGPQVRFQKGTVEKLVKGRIPVEVMDMRLYGMMNGKAILEDALQKIN"
     gene            3484..4848
                     /locus_tag="KB927_002392"
     CDS             3484..4848
                     /locus_tag="KB927_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6841282.1"
                     /translation="MSFMDKFQSAIERLLVPLSTKLNAQRHICAVRDAFILSFPLTMA
                     GSLMVLLNNVFLSADGFMFKILQFDKLFPGIVKFQAVFAPVVKGSADIFSILIVFLIA
                     RNLAKLMEGDDLLTGLTAISVYFIIYPDYFDNEGVNYLTNQYMGAQGLFVAILVGLLV
                     GELMSRLAKSDKLEIKMPEQVPPAVARSFKVLIPIIITTVFFSVLNYFVKMAAPGGLH
                     ELIYNIIQTPLTRMSQSLFSVIILALLSQLLWAMGIHGPNTIAAIRDTMFSEAGNANL
                     LHYAESGTTWGAPFPITYSGLATAFAEYGGSGATLGLIIAILIFSKNKESKSIGKLSF
                     VPGLFNINEMVIFGLPIILNPIYIIPFIIAPLVNIMIGYTAVMILKIMPPVTIGIPWT
                     TPGPLMPFLGTGGNIVALFVGFICLAVSVLIYSPFVIAANKAAIIEDEMENEIQSQEV
                     VESI"
     gene            4904..5218
                     /locus_tag="KB927_002393"
     CDS             4904..5218
                     /locus_tag="KB927_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6841283.1"
                     /translation="MEGIELTAFSIISNVGMAKSLAIEALRDARKGKYNEAEKKMAEA
                     SEYFVKGHHAHTSLIQKEAAGEKVELSLIIMHAEDQLMSTETTKLLIEEMIEMFKQLN
                     NK"
     gene            5552..6598
                     /locus_tag="KB927_002394"
     CDS             5552..6598
                     /locus_tag="KB927_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6841284.1"
                     /translation="MMNSTEIAKIAGVSRSTVSRVINNYSNVSEETREKVLRVIKEHE
                     YVPHASARMLAGSQNKVIGLFIIDLIHEEVGLKNRITKSPYYLEFTSSVIETASEMDY
                     LVLVHIIHSVAGYEKIKESFYNKTISGGIFIGQNDDDESIKTIIDRGYKVVLLDQSIR
                     PEDATYNQCMIVNADNYNGAYCATKYLIDKKHKQIAHITGGTVKFSSKDRIRGYKKAL
                     EDAGIEVNKNLIVNSEFVENAGYEAAKKLFNGNSEFSAIFASNDKIAFGAIKAIQERG
                     LKVPDDISVIGFDDIESSKYFNPPLTSMKMKLGEMADIATKSIVASIEGETKPSINVV
                     PVSLVERESCGILQ"
     gene            7210..7707
                     /locus_tag="KB927_002395"
     CDS             7210..7707
                     /locus_tag="KB927_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841285.1"
                     /translation="MKQRIGNNLALIYSGALLIQDILGYPLRLEHIQTVLINSYEQLI
                     VDTSLGSEQTVFDRVKTLLVMNSHKFLTNSDNKHTPSTIWGKVSIKKNGDIKVNIFPI
                     PFEDLLRREFQVKDLTYLFRQLLDSGNMCAEKGRRTKRIHMNRQVLPTYEILLPSSLK
                     SYFRL"
     gene            7750..7904
                     /locus_tag="KB927_002396"
                     /pseudo
     CDS             7750..7904
                     /locus_tag="KB927_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314395.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         2756 a         1218 c         1644 g         2286 t
ORIGIN      
        1 gcaaccggag tttcttgatg aaaatatact tctatcatta caagctcgtt tggtgtaaga
       61 tgggtataag tcatttatgt tcactctcct tgtatgcttt agcgggtatt acgatttgag
      121 tgtaacataa atggcttttt tatttgtctc gcttaattat acaaacggcg tcattagaaa
      181 atgatggtaa attatttgat ggtaacggtg atgtaacaac ggtaatgaaa ttattgcttt
      241 aacagtttag cgtgataaaa atctatacct tcttaagttg atttattaac ttgagaaggt
      301 atttttttct gaaaaatgat aatgaaaatc aaaatgttca tttctatcaa ttttgaagtc
      361 aaaaaaataa agtacagccc agaaatttgc tctgtacttt aaaaaactag ttaaatgaag
      421 atgaaatcgc tcccttattt tttagtattg gtggaattaa aaggtacttt ttaaacaaaa
      481 actacacata aaaaataaaa aaaataaaaa aagtattgaa atgtaattgc tttcagtata
      541 tgctatatct ataaacgcgc gttcatggga tgttcatcgt ataaaaaaag gtggaaatga
      601 gcgtatcgtt tttcttttta acaaatcatg aacgcgcgtt tatgagtttg aatcaagctg
      661 caatataaga aggcaaactg caagaccttc attttaagga gaagtgttat ggggaaaata
      721 agtttaggaa tagacatagg agggacgttc attaagtatg cattaataga caagcaacat
      781 cgcatcaaag agaagtggaa agtcgaaacg gttaagtaca atacagccga cgaattttac
      841 gattatatat gttcaaatat aagaaatgta gatgaaattg acaaaatcgg tgtaagcgca
      901 cccggcctta ttgatgaaga ttcgaatgtt aaatcctatg ctgctcctaa cgtagctata
      961 atgtacggca caaatatcaa taatgagatc aacaaaagga caaataaaaa agtgtccgca
     1021 atcaatgatg caaaagcggc aggtttatgt gagtttaaaa ttggaaatgc aaagggatac
     1081 aaatcttcag cgtttttgat tataggtaca ggaacaggcg gatgcatatg cgacgaaaac
     1141 ggagttgtgt atggaaaaga ttcgtttgcg ggggaattcc ataatatgcc ttttgtaaac
     1201 gctgagatag gcggccttga taagatgggt gattatgctt cgataaccgg attggttaat
     1261 ttatacaata aaaaagctaa tcgggaggag caggttcagt atggaaatga ggtttgcaag
     1321 aagtacctaa acggaaatga atcagctgtg tcttcagtag atgaatggat aggaaacata
     1381 gtggctcaat taatagtaat caccgttttt tataatcctg aagtgatatg catcggtgga
     1441 ggaatatccg aagaaaactg gttcatcaat aaagtaagag aaacgtataa gaaaacctgt
     1501 agggagtatt tagaagcgga ttttattact accgaaatca atagatgcaa gcataataac
     1561 gatgccaaca tactgggtgc tgttataaaa gcttctatct aaaatacaca acagttttgt
     1621 ttcaagaaag aatgtttgaa aataaattta tattgaaaac gaaggagaag attcagtgat
     1681 atacgaagaa ttagacaaat tccaagatga tttcctatgg ggatcggcat ctgcagcgta
     1741 tcaggttgaa ggagcatggg acaaagatgg aaagggggaa agtgtatggg atgtgtacac
     1801 ccgccaaccg gggacaacat ttaagaatac aaacgggaat atcgcggtcg accattacaa
     1861 tagatacaaa gaagacgtag ctttaatggc tgaaatggga ttgaaagctt atagattctc
     1921 aattgcatgg acacgtattt atcccaatgg aagaaatgaa gtaaatgaag aaggcttaaa
     1981 attttatgaa aacttgatag atgaacttat cgcgaacaat atccaaccaa tcattacgtt
     2041 gtaccattgg gatttacctc aacatcttca agatttgtac ggcggatggg aatcaagaga
     2101 aatcattcat gattttaatg aatactgtgt aacgttattc aagagatttg ggaataaagt
     2161 taagcactgg gtatcattga atgaacaaaa tatatttgta acactaggtt acgtaaccgc
     2221 tatgcacccg ccagctgtta aagatcaaaa gagaatgctt gaggcgaatc atatagcgaa
     2281 cttagctaat gctaccgtaa ttgaatcctt caaaaaatat gttccagacg gtatgattgg
     2341 accaagcttt gcatttggac cagtttatcc attcagttgc gatccaaaag atgttttatc
     2401 cgcagaaaat gcagaggatt taaattgcaa ttggtggctc gatgtttatt gcaaaggtaa
     2461 atatccagtg ttcgctttta aatattacga aagacttggg atcgcaccca ctattgaaga
     2521 tggagatctt gaattgttgg aaagagtaaa accagatttt atcggaataa attattacca
     2581 aacaagcaca gttgcattca atccgcttga tggagtaggg caatcggaag gtatcaataa
     2641 cacaggtaaa aaaggcacca ctaaagaaag cggattaccc ggagtttata aaaatgcaaa
     2701 aaatgcacat ctggaaacaa caaattggga ctgggcaatt gatcctactg gtttaagaat
     2761 tggactaaga agattgacca gcaaatataa tcttccaata cttattacag aaaacgggct
     2821 tggagaattc gacaagcttg aagaagacga cactgtcaat gatgctcaca gaatcgatta
     2881 cttgagcgca catatcaagg cttgtaaaga agcaataaca gatggtgttg atcttctagg
     2941 ctactgcacg tggtcattta cagatttgtt aagctggttg aatggttatc aaaaacgcta
     3001 tggatttgtg tatgtggaca gagatgaaaa tgatcaaaaa gatttgagaa gaatcaaaaa
     3061 gaacagcttc tattggtaca aaaatgttat tcgcaccaat ggagaagagt tataagaatc
     3121 gttcacaatc aatgaatatg aaaaaacaag gagagataga ccatgaaaaa aattttacta
     3181 gtatgttcag caggaatgtc cacaagtttg cttgtgacca aaatgagaaa ctccgcaaag
     3241 gaaaaaggaa ttgaagtaga aatagatgct cttccagttg cagaggcaag tacggccgtt
     3301 gataatgtcg atatcgttct tttaggacca caagtgcgtt tccagaaagg gaccgttgaa
     3361 aaacttgtaa aaggcagaat tcccgtagaa gtgatggaca tgcggctgta tggaatgatg
     3421 aatggaaaag cgattttaga agatgcttta caaaaaataa actaggaaag gaggctaaaa
     3481 aaaatgagtt ttatggacaa atttcaaagt gctatagaaa gattgttagt gcctttatct
     3541 acaaagttga acgctcaaag acacatatgc gcagtaagag atgcttttat tttatcattc
     3601 ccattaacga tggcaggatc attgatggtg ttattgaata atgttttctt gtcagcagat
     3661 ggattcatgt ttaaaatctt gcaattcgat aaactttttc cgggtattgt taaattccaa
     3721 gcagtgttcg ctccagttgt taaaggttca gctgatattt tctcgattct gattgtgttt
     3781 ttgatagcca gaaaccttgc gaaactaatg gaaggcgatg atttgttgac aggtttgacc
     3841 gcaatctctg tttatttcat catctatcct gattatttcg ataatgaagg agtaaattat
     3901 ctaacaaatc aatatatggg cgcacaaggg ttgtttgtag caattttggt tgggctcttg
     3961 gtcggcgaac taatgtctag attagcaaaa tcagataagt tagaaattaa aatgccagaa
     4021 caagtacctc cagcagttgc aagatccttc aaagtgttga tcccgattat catcacgacg
     4081 gttttcttct ccgtcctcaa ctactttgta aaaatggctg caccgggcgg attacatgaa
     4141 ttaatttata acatcattca aacaccattg accagaatga gtcaaagttt attctcagtg
     4201 attattttag cattattatc tcaattgcta tgggctatgg gaatacacgg accaaatacg
     4261 attgcagcta ttcgagatac catgttctcg gaagccggaa acgcaaacct cttacattat
     4321 gctgaaagcg gtactacatg gggagcgcct tttccgataa cgtacagtgg tttagctact
     4381 gctttcgctg aatatggcgg ttcaggagcg acattgggtc taatcattgc tatattgatt
     4441 ttctcgaaaa ataaggaatc gaaaagtatt ggcaaacttt cttttgtacc cggtttgttc
     4501 aatataaacg aaatggttat ctttggttta ccgattattc tgaatccgat ttacattatt
     4561 ccatttatta ttgcgccact ggttaacatt atgattggtt ataccgcagt tatgattctt
     4621 aagattatgc cgccggtaac gattggtatt ccttggacaa caccaggacc attgatgcct
     4681 ttcttgggta caggcggaaa tatcgtcgca ctgtttgtcg gattcatctg tcttgcggtg
     4741 agtgtattga tttactcgcc gtttgtaatc gcagcgaata aagcagcgat tattgaagat
     4801 gaaatggaga atgaaataca gtcacaagaa gtagtagaat cgatttaaaa aagctgcagt
     4861 acgctgagaa caaaccgaaa gattcaagat aggagattta cacatggaag gaattgaatt
     4921 aactgctttt agtataatca gtaatgttgg aatggccaaa tcattggcta ttgaagcatt
     4981 aagagatgcc agaaaaggaa agtacaatga agcagaaaag aaaatggctg aagcatcgga
     5041 atattttgtg aaaggccatc atgcacatac ttctttgata caaaaagaag ctgctggcga
     5101 aaaagttgaa ctttcgttaa taatcatgca cgcagaagat caattgatgt cgacggagac
     5161 aactaaatta ttaatcgaag aaatgataga aatgttcaaa cagttaaaca ataaataagt
     5221 gaacatgaaa gagaaaatat tagacgaact agaattgctt gcttacttta caggcagaat
     5281 ctgatgccag cagcaaaaca tagagcaccc aggatgaaat ataatcctgg gtgccttatt
     5341 tttagaacaa aacaccgggg tggtagtttg ttctgcggtt gaaggcattt gctgatggtt
     5401 tctgcatgaa aggtattgcc aaaagtctcc ttttgctgga atcctgaagc aggcagagtt
     5461 tttcgaaaaa cagaaaaaga ttgaaaaaaa tggacaaata atatagtgtt gcagtatgaa
     5521 cacgagttta cgaacgaaag gagatgcctt tatgatgaat agtactgaaa ttgcaaaaat
     5581 tgccggagta tcacgcagta ctgtatccag agtgataaat aattattcaa atgtctcgga
     5641 agaaacaaga gaaaaggttt taagagtaat taaggaacat gagtatgtgc cacatgcttc
     5701 agcaaggatg cttgcaggaa gccaaaataa ggtgatcggc ttatttatta tagacctgat
     5761 acatgaagaa gttggactaa aaaatagaat taccaaaagt ccgtattatc tagaatttac
     5821 tagttcagtg atagaaacag caagtgagat ggattacctg gttcttgtcc atattataca
     5881 tagcgtcgca ggctatgaaa aaattaaaga gagtttttat aataagacaa tttctggtgg
     5941 gattttcata ggccagaatg acgacgatga atcgataaaa acaatcattg atagagggta
     6001 taaagttgtg ctgctcgatc aatcaatcag acctgaagat gccacctata accagtgcat
     6061 gatagtgaat gcggacaatt acaacggcgc ttattgtgcg acaaaatatc tcatagataa
     6121 aaaacataaa caaatcgcac atattacagg cggtacggtc aaattctctt ctaaagacag
     6181 gataagagga tacaaaaaag cattagaaga tgcagggata gaagtaaata agaacttgat
     6241 tgtaaatagc gaatttgtgg aaaatgctgg atatgaggct gcgaaaaaat tatttaatgg
     6301 aaatagtgag ttttcggcta tttttgccag taatgataag atagcatttg gagcaatcaa
     6361 agctattcaa gaaagaggtc tcaaagttcc agatgacatc tctgttatag gatttgatga
     6421 tattgaatcg tctaaatatt ttaatccgcc attgacttct atgaaaatga agttaggaga
     6481 aatggctgat atcgccacaa agtcgattgt tgcatcgatt gaaggtgaaa cgaagccatc
     6541 tataaatgta gtacctgtct cattagtgga aagggagagt tgtgggattt tgcagtagca
     6601 aaacttgctg aattagttgg agctgattat ttgattattt tgattgaggt agacaatgtc
     6661 tgtgtctatg tcgacttgaa aagtaaagta cagcgcccaa aaatgctctg tactttaaat
     6721 ctcagcaaaa acaggaatat ttcccaaaca tctccttctt tgagtaatta tacaaaaatt
     6781 atgcagactt tcttttttca tgataagata atttaaaaag tttttaaacg atttctcctc
     6841 ctctttttct tatatcgggg gagcatattt ttttgtagac taggggatta taagttcagc
     6901 catcaatgtc tagctcccaa gtcctgacct agtgaaaaaa agataaattt gccccattgc
     6961 gcgcttcgct gctcattcag ggtcaaattt cctatttttt cataggtcaa ggcggacttg
     7021 tccgcttttc ttatattaag tttacaaagg atgcgaatca cgcagagaaa gttaaaagtc
     7081 tttcttctaa tacttttggt tggggtataa agttatttct tttgaaactc tttgaacaag
     7141 ggattgcaaa aattgaagca acttttgtcg aagctcaaaa aaatatgggc tgttttacct
     7201 gaacattctt tgaagcaacg cattggtaat aatctagctt tgatttatag tggagctctc
     7261 ctaattcaag atatactggg ctatccttta cgattagagc atatacagac ggtgcttatt
     7321 aattcgtacg aacagttaat cgtagatact agtttaggaa gtgagcaaac ggtatttgac
     7381 cgagtgaaaa cattgttggt gatgaatagc cataaatttt taacaaacag tgacaacaaa
     7441 catacgccca gtacgatttg gggaaaagta tcaattaaaa aaaatgggga tattaaggta
     7501 aatatttttc ctatcccgtt tgaggacttg ttaaggcgag aatttcaagt aaaggatcta
     7561 acctatcttt ttagacaatt gcttgattcg ggtaatatgt gtgcagaaaa agggagaaga
     7621 acgaaacgta ttcacatgaa tcgtcaagtt cttccaacat acgaaattct attaccttct
     7681 tcactcaaat cgtattttcg attgtaattt agaataaacc aaagtatgaa agtgaggcac
     7741 catgttatta agcaactgaa agatattcct attccaatgc ccgctatttc agaacaacaa
     7801 aaaatcggca ctttcttcaa acaactcgac gacaccatta cccttcacca acgtaagtta
     7861 gatttactaa aagaaacgaa aaaaggcttc ttacaaaaga tgtt
//
LOCUS       DADVXM010000099         7503 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.105, whole genome shotgun sequence.
ACCESSION   DADVXM010000099 DADVXM010000000
VERSION     DADVXM010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.105"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..658
                     /locus_tag="KB927_002397"
     CDS             <1..658
                     /locus_tag="KB927_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBB6841286.1"
                     /translation="DDVYKINKITHQENRQKNLIVQNLNYGTNQYSVDNSKFELCDTS
                     MKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLSTKNNKLDEELIETFIE
                     ENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAEKEQKIQLKIIYEICNN
                     KYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNKALELIELQISEGIDKQ
                     "
     gene            734..952
                     /locus_tag="KB927_002398"
     CDS             734..952
                     /locus_tag="KB927_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841287.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            939..3617
                     /locus_tag="KB927_002399"
     CDS             939..3617
                     /locus_tag="KB927_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841288.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            3608..3805
                     /locus_tag="KB927_002400"
     CDS             3608..3805
                     /locus_tag="KB927_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841289.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            3809..4420
                     /gene="mobC"
                     /locus_tag="KB927_002401"
     CDS             3809..4420
                     /gene="mobC"
                     /locus_tag="KB927_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBB6841290.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            4405..5796
                     /locus_tag="KB927_002402"
     CDS             4405..5796
                     /locus_tag="KB927_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBB6841291.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            6012..6326
                     /locus_tag="KB927_002403"
     CDS             6012..6326
                     /locus_tag="KB927_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841292.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            6319..6813
                     /locus_tag="KB927_002404"
     CDS             6319..6813
                     /locus_tag="KB927_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841293.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            6881..7195
                     /locus_tag="KB927_002405"
     CDS             6881..7195
                     /locus_tag="KB927_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841294.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            7294..>7503
                     /locus_tag="KB927_002406"
     CDS             7294..>7503
                     /locus_tag="KB927_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6841295.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
BASE COUNT         2891 a         1012 c         1441 g         2159 t
ORIGIN      
        1 agatgatgtt tataaaatta ataagataac ccatcaagaa aatagacaaa aaaacttgat
       61 agttcaaaat ttgaactatg gaacaaatca atattctgtt gataattcaa aatttgaact
      121 atgcgacaca tcaatgaaaa caagagacaa aaacaatttt gctgatagtt caaaaaatga
      181 actagaatta tataagtctt ataaagatag taaagatatt aaagaatcac ataatgatga
      241 tcttcttgaa tcactttcaa ctaaaaataa taaattagat gaagaattga tcgaaacatt
      301 tattgaagaa aatcttctta aacaaatatg gggagaaagt attgtgaatt gcttaaaact
      361 ggctagcaat agtgattatc gtcaattcga caactggtac aaaaaattca aatatgcgat
      421 tagatctgct gaaaaagaac aaaaaattca actgaaaatt atctatgaaa tttgtaataa
      481 caagtatttt gtagatcatg ttagagaaca gctatcaatg actttacgtg acttgatacg
      541 aagagcaaaa acagatcatc gtatcaaaca aaaagacgat tatatctttg cttctctaaa
      601 aaataaagcg ttagaactaa ttgaattgca aatcagcgaa ggaatagata agcaataaga
      661 atagaattga gtcaaatgaa atggaggggt atctccactt catttgagaa ctttgaatat
      721 aggaggggtt attttgatta aaaatcgttt aatagatcaa gtttggtgtc tagatcaaaa
      781 tacagatagt ctcgaattaa tcgagactat ttgcttcaac actatagttc tcgatttaag
      841 agctgaaaat gataattgtg taactcatgt cataattaat caaaaaatgg ctcagaagct
      901 ctctgagagc ctcagaaaat gggctaaggg aggtaacgat gaaaataatt gaaaaaaaga
      961 ttgccaataa aaaaataaat tggttggttg ttaattttct tgttctgata gctatgatta
     1021 tttttacaag taatattgct catgcgagta ttttcaattg gtttgatgac acaaaaagtc
     1081 aaacagagtt tttgaataat tctctttata gaccttacct aaaaaagtac aatggagatt
     1141 tccttagtca gttcgggatt tggctcggat gggctgtggt aaaaggcatg tttactgtga
     1201 cagattcgat tcaaaatatg attccagatg tgctggattt gttcaatttc attgaaagta
     1261 cagggctaaa taatgtttat caatcagccg taaatacaat tgtcattgga ttaatgatcc
     1321 tttcattgat gtttgttggt tacaaaatga ttactggaaa aggaacagtg gatttaaaat
     1381 cggttggaat gaacgtagtg atgtctatag cattaatact tttaatgcca accatgattt
     1441 ctagtggtat tcaatttgct aaaacatttt ataaggactc tactacgatt acaaattcag
     1501 atgacggagt cgcttggtca ttgataaaac aaggagtaac agatttagca tatattaata
     1561 aaacagatca gtactcaagc attgataaaa cggaggatcg aaataattta acacgaaaaa
     1621 attttcaaca gacggatctc acacaagtgt taacggataa agtgattgat aaattggaaa
     1681 aagaaaatcc aattgcggac aatcttcgtt atgaattagt tgaaaattct aataatgaat
     1741 ttgttgctac aaagttttct gacaacttct tatcaacatt ttctgatagc ttgaaatcag
     1801 gctattaccg ataccaagca aatctatggg ggatttcaat tgggttgaca gcgttagcaa
     1861 tcgcctatgt gttcagcgcg tttgtgatca ttacagcaat actagaactt gcatttaaac
     1921 gtgtgttagg tgttcttgtt tttgcaacag atattgagac aggacagcgt tcaaaagttg
     1981 ttctatcaga tattctacaa tgttacttaa ctgttgggtt tcaaggattt gggttatcaa
     2041 tgtttgctat gtttatcaat tttctgaact caggacaagg tatctcaaca aatattttta
     2101 taaaaacaat tgcttatatc tgtgccgttt ttgttttaat caaaggcagt ggaacagtca
     2161 tgagatactt tggtgttgat attggactca aagaaggcta tgggcaactt gcttctgctt
     2221 ttggaatggg cgcaatgctg tttagaaaag gatcaaatgg atttaatcgt gctaaaggaa
     2281 gcggagaagg agaagatcga aaaccagaaa agaatttcgg cgaaactcta tcaaaaaaag
     2341 ctggcaaaac tggaagagct ttgggatatg cccatgaacg tggattatcc ggtttagctt
     2401 cagatggagc tacaatggct agtgaaagag caacaaaacc atttaagagt atgcgtgata
     2461 tagctaatga taccaagaat aagtttaaag aaggtttaga tgatggtaca gtgtccgcta
     2521 ttaataaaaa tagcaaacct atgttagcta aaaataaaga agatgaaact ggaaaatatg
     2581 ctgattccgt gccaacacgt ctttcagata gaaaagatgg tgctaaagtt gaaaatgccg
     2641 atagaattat gtctagttct gaacgtatgc gtgaagcaat gaaaaataat gctgaatcga
     2701 ataataatcc tgcaagcgca attcagcaaa aagtccaaca agatattgaa gaacgtaaaa
     2761 atgctatgca cggtcaagct aagtctgctg aagaattaat taatcagaag cgtcatgaag
     2821 cgaaatacac gcctgaagca atgaatcgcg aggaaataat gttaaggaaa cgtgtagaag
     2881 ggcggacagg cgctaatatt gacggaaaag aagcgttgac caaagaaaga attcaagaag
     2941 ctaaaaattc aaatacagga ttagaaaaat tagtcaaaga aaatccacaa aattctacaa
     3001 gtagtcatgg tggccgatca gtagatgtcc gagaaaatat tcaaggttca ctgaatggtc
     3061 atgttggacg gaatgttgat gtaagagaga atttacaaag ttcttcaaat gctcaaggta
     3121 ctaagacaat tgatgttcga gaaaatctgc aaagtagcag tacaagtcaa ccaaaaacag
     3181 tagatgttcg agaaaatgta caaaattcta caagtagtca agggtttaaa tcagtggatg
     3241 tccgagagaa tgtgcaaggt agcagtgcaa gtcaaccaaa aacagtagat gtccgagaaa
     3301 atgtacaaag ttctacaagt agtcaaggat tcaaaacagt agatgttcgg gagaacattc
     3361 aaaaagatag tggagaaatg aaagaaaaaa cacaaaaaat caatatcgtt gaagacagaa
     3421 agtcagcgaa aaaatttgat tcaaatcatg aaacagtgat tattgatagt gaaatccgtg
     3481 aaaatgataa gggatcaaaa tcaagacgaa gattcactta tgaagacaat gagttattca
     3541 gagatacact taatgatcct aatccacttt tcgataattt attaagaaat aaaagggggg
     3601 gattgtcatg caattaattc taaagattag tacgcatgat ttcttagaac ttgacgaatt
     3661 atgtgaatca gtaaagaacg caacaaatga aaaaatcacg gtcactaatt atattgaact
     3721 gatgattcaa gaagaattaa agatgaaaaa tgaaatagag agcaatttca aatgttgctc
     3781 tctagaaaaa aatgtgaggg gataatcaat ggatgataaa caaaaaatgt acgaaaaaaa
     3841 tcgcaaacat agtgaggcct taaattttcg tgtcgataaa aagacttatc ttgaactgac
     3901 attgattgca aaacaaaggg gaatttctag agcagacgtt tgccgtgagc ggttaaaggg
     3961 actcaaatat gaaccgccgt tgttagctga agatgatagg gtagttttaa ccaaacagtt
     4021 aaatcaaatt ggtaacaatt tgaatcaagc ggtaaaggca ttaaatatca ttgctaaata
     4081 ttttagagaa gaatctgaag ataaaaaaga aaagagccta cattttagtt ttgatgctag
     4141 ccgttacaac atttttaaag atgaacttgc gaatagcata gcaaaaaagt tgatgattag
     4201 ttatccagat gacatttttt tggagtccaa tcggagtgcc ccctcttttt ttaaattatc
     4261 agaagtagaa aaagaatatt tcgaatattg gatagaaaag caaactagac cgggtacgaa
     4321 agaagagtat tcccaaaaag ttgatcggaa tttaattcac tcaattcaga ttattgcaag
     4381 tttaaaagat gaggtgaaac aactttggga gctactataa catcgaaagg acgcaagaaa
     4441 aatttatcct cgctattaca atatgcagct aatccttcaa aaaaagaaaa atgtgttgca
     4501 gtctcaggaa taaattgtag tgatgatagt gaggaagcac tgcaagaaat gaatttagta
     4561 cgtaccaaga tgaataaatc taaagatata gcacaagcgt ttcatgttat tcattcgttt
     4621 gataagagta cttctaaaga gttaagtatt gataaaatgc acgaaatagc tgtcgaattt
     4681 gcagagaaag cttttccaaa ttcgcaaatc attgttgcaa gtcacaatga taaagatcat
     4741 tttcatagtc atcttgtcat taataatatt aacatggaaa catgtaaaag gttgcgtatt
     4801 gaccctaaag atttagaact aatgcgaaaa attaacgatc aagtcctcaa tgaacatggt
     4861 cttgaatcag tgaataatga gtactatgaa aacttagaaa agagaaccaa tctttattca
     4921 aacgatcctt ctaagatgaa atatggaaaa attaattatc aagagtttgt gcaaaatgcg
     4981 atcgaagcaa cgttggaaaa atgcgaagtg aattcttttg aagatttttc ggatcatttg
     5041 gcaaaagaat ataacattga agtttatcaa ttttcaaaaa caaataacaa acttggctat
     5101 gttctttaca aacaaggtgt aaatttctat gagcgtagag gtgagttaat tactttagga
     5161 agagataaac aatctagaaa agaaaaaagt cagtatgtcg aacgtacttt tagtgcaaga
     5221 aagttaggga aaagatattc atttgaatct gtttctgaac aacttgaaaa gaatttagaa
     5281 gaatcacata taaaaaattt ttttaatatg gaaagagagc aagttatgtc gctaattagt
     5341 ggagtaaatt acaaaactgg tgagttaaat gtaccgtttg tggaattaga ttccatcgca
     5401 caaaagcaat ttagcgaccg tgaaggcgat gaaaaattca ttaaatatga tgacttcttg
     5461 cgagaggtag acaagcattt tgtaaataca atgtctttag aagatgatca agaatacacg
     5521 attaaacttc atacggatgt gaatcctcaa actttacgta gtgcgaaaag taaaacaatt
     5581 tctattaaaa agactgatca gaaagagtta tttctaccgg caaagggttt tgaaaattgt
     5641 tctcatacac cttctgctaa acagattcac tatcaaatca gtcgcataat gaatgacgat
     5701 gtaaaaatgt atcgtgctaa aaaggattat gaattcacac aacaaatgat tgaaaatcag
     5761 caaaaaaggc aacaaaattt tgaaatggaa ttctgaatgg gcttgttagt ggactttcca
     5821 gttttttgcc tatgaagagt tgcttggaaa gaagcagttt ttaggacata cgccagctac
     5881 ccatctactt gccagtcaat ccgccccgct cacgctaggc tactttctgg caagtcagat
     5941 ggcgggtaaa tctctgaggg agcaagctcc ctacagactc cctcccaaaa aaagaaaggt
     6001 ggaagaaaaa aatgaactat ccatatttta aagtctcggc ttcagaagaa actaaagaaa
     6061 tattcaacaa tttttacaac caaaacaaag gaatttttgg ttcaaaggca aatatgtttc
     6121 gtgttatggt ttcaaattta ccagtgttag ctagtccatc aaataataaa tttaatgatc
     6181 ctgaaagcat taaatttgaa caaaaaattt cagaactaga atcaatgata agtaatgaag
     6241 taattgaaaa gctggatgac attgatcaaa agttatcgta ttctctaaaa aacaaataca
     6301 aaacggagga gaaaaaagat gtttaaagtt tacttcccgt ttcagtggct cgttaaagga
     6361 attcttttag tgctactagg attgattctt tttggaagtt atctaacaat taaagccaga
     6421 cattttccag aagaaaagcc aataaaaatt gtaacaaaag atttaaaaat aggtgaaact
     6481 tatcaggcag atggggttga actaacattt aaaaatattg aagtgaccga aaaaagaaat
     6541 gaatttgcac aacatgatcg tgtattacaa gtgacctata cacttataaa tgatacagaa
     6601 aatccgatac gtccacaaca atggtcgatt gaaaataagg atggtgaaga actttatgag
     6661 tatgatatga tattggataa tccagagtat attgaaagtg gcaaagaaga aacagtaaat
     6721 tactattatg aattaccgat tgaaaggcag gactaccaaa tcgtagtacg tagagagaat
     6781 ggttacatag ttgggttgcc atttacttta taagttttat tttgttagta gtttttaagg
     6841 taatatcagt tttgtgattt ttgaaaatgg aactgggaga atggctgagg aaaataaagt
     6901 tgttccgttt gaaacattag tgataaataa ggaagagttt gagcaacttt ttcttgattt
     6961 ttttattcaa tatgacatga tttatgattt tagttcgtca ctagatttat ttgaattaga
     7021 agcagaaata atagaaaaca gtcgagagaa gaatggtaaa atcattattt cagtagaaaa
     7081 attcaatgaa ttattctcac aaacatttga aatagatcca gactattatc aaccacaaga
     7141 agtttttcga gagtttagaa ataagattat tggttttagt caaactacaa aatgaaagct
     7201 taataaagca agtgttgata gaattattcc tcaacgcttg ctttatttta tgggcacttc
     7261 ataatagagg tatagagaag agaggtattc attttggata ctattactcc aacaaacttc
     7321 aaagaaaata taggtaaagt gttgcaagaa gtagttcatt caaattctga aatagaaatt
     7381 actagggatt ctaaaaatgg attgaacgat ggcgtcatta tgatttctaa gagaaaatgg
     7441 gagttgttac aagaagaact ttatttacaa cgaacgggta catgggctta tgtatctgat
     7501 tta
//
LOCUS       DADVXM010000100         7158 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.106, whole genome shotgun sequence.
ACCESSION   DADVXM010000100 DADVXM010000000
VERSION     DADVXM010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.106"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            24..1316
                     /locus_tag="KB927_002407"
                     /pseudo
     CDS             24..1316
                     /locus_tag="KB927_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            1835..2569
                     /locus_tag="KB927_002408"
     CDS             1835..2569
                     /locus_tag="KB927_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6841296.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            2585..3754
                     /locus_tag="KB927_002409"
     CDS             2585..3754
                     /locus_tag="KB927_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6841297.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            3770..4765
                     /gene="lacD"
                     /locus_tag="KB927_002410"
     CDS             3770..4765
                     /gene="lacD"
                     /locus_tag="KB927_002410"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBB6841298.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            4844..5770
                     /locus_tag="KB927_002411"
     CDS             4844..5770
                     /locus_tag="KB927_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBB6841299.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            5789..7039
                     /locus_tag="KB927_002412"
     CDS             5789..7039
                     /locus_tag="KB927_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6841300.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDANRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2348 a         1194 c         1470 g         2146 t
ORIGIN      
        1 taagatcaag aggtgattac acgatggcta gaaagaaaag aaatcctgat gccgaaaagt
       61 tagctgaatc cattctgaat gcctatcaac ctgaatctgt cgatgacatg caagatgctt
      121 tgaaagatgt gtttgggccc ctttttgaaa aaatgcttca aggagaattg aataatcatt
      181 taggttatga tgcccattct aaagagccta aggaacacga taaccgtcga aatggctatg
      241 gaactaaaac gcttaaaacc agttttggtg aagtagctat tgatgttcct agagaccggg
      301 aagcttcctt tgaaccagag ttaattccta agagaaaacg agatgtctcc gacatcgaag
      361 ggaaggttct ttccatgtat gcacgaggaa tgagtcaatg agatattgcc gcaaccgtcg
      421 aagctattta tggctttgat atttcccatg aaatgatttc agatatcact gacgctgtcc
      481 ttcctgaatt ggaagaatgg caagcccgcc ccctagcaaa gtgttatgcc tttctattcg
      541 ttgattgtat gtatgttact ttacgagaaa attatgaagc caaagaatat gctgtacaca
      601 ccattcttgg ctatgatctc aaaggaaata aggagatttt aggattatgg ttaaatcaaa
      661 cagaatctaa aaatcgctgg atgcaagtat ttgatgaact gaaagcacgt ggtgtcgaag
      721 atgtcttttt catttcgatg gacggtgttt ctggcctcga agaaggcgca aaagcgatct
      781 ttccatcggt aattgttcag cgctgtattg ttcatcttgt tcgaaatgca ttgcgctata
      841 ttccaagtaa ggactataag gaagtctgcc gagatatgaa aaagttctac ggtgcttctt
      901 ctctaaacgc tgcacatgct gcttttgaca gttttcaaaa tcggtggtct cattattctg
      961 gtgctgtaga tgtctggaaa cggaactttg cacatgttga acaactattt gattatggta
     1021 gtgccattcg aaaaattatg tacactacca atgcggttga aagtgtccac tccagcttca
     1081 gaaaagtcac aaaaaaagga gcgttctcta atgagaatgc actcctaaaa ctactttatt
     1141 tacgcacgaa agaattacac gcgaagtggt caggtggtcg aattcaaaac tgggctatgg
     1201 tgcttaatca gttaatgatc aacgagacct tctcctctag aatgaaaagt atgcgattta
     1261 ccttccgtaa caacggtagg tttattcaac tatgtgtccg atcaaaattt atctgatttc
     1321 aaaatagccg agagaattat ggtggttaaa aactcttaac tatttaactt ccacagttta
     1381 gttgacaaac ccacttaatt ctgataacga aaaacatatt cgaatgatta aacagaagta
     1441 aatacttatt taaataactt ttaattttca tgttcataaa tgatttgaaa ccaaagcaaa
     1501 tgcgttgcac ttttcctccg tcttccgaaa atcgttcaat tcactggtaa gtagtcattt
     1561 gatagtttga ggcaaattgt tgattgatga agggtaggag ctaaaaaaag ataccagttg
     1621 aagagagaaa aagaaaaaaa tagagggtgt tcttgaatga aaaaagttgg aaaattattt
     1681 ttcatttcct tttattccta ttaaaatcag tgatgtcaat catattaaca agactaaaaa
     1741 tgaaaataaa aaaaagattg ttcttagtat tgactcataa aaaataccac tactatactt
     1801 acattgtggt tatagccagt taggagagac atcgatgcaa aatacctttc aatcaaaatc
     1861 actttattat cagctggtag aaatattgaa acaacgaatc gaaaacagta tggtcgctca
     1921 tgacaagctg ccatcagaaa gagagttgac cagtttttat ggcgttagtc gcacgacggt
     1981 gcgactagca ttgcaagaac tggaaaaaat gggctacatt tatcgacagc atggaaaagg
     2041 aacctttgtt tcggaattaa ggacaaatgc gactgatcta gctggcgcat atagttttac
     2101 cgaacaaatg cgggcaatgg gcaaacatcc tgaaaccaag atattggcct tcaagaagat
     2161 tgaagcaact aaatatttag cgagtcatct gaatgttcaa ctaggtgagc ctttatttca
     2221 attagaccga ttgcgcttag ctgatgattt gccaatgatg atcgagaaat cctatttgcc
     2281 agtgaagcta tttatgtccc tttctcaaga aattctattt ctgaaacctt tatataattt
     2341 gttttcagag aatttcaatc aaatcgtacg gttggctgac gaggaatttt atgccagcat
     2401 tgtccagaaa gaagatagtg agttgctaaa tattccagaa ggatcaccag tgctccattt
     2461 agttcgctca acctataatc tcgagaacga agtgattgaa tttacattaa gtgtagcgcg
     2521 ggctgataaa tttcattata agatcaggca tctgcgttcc actaactgaa ttggaggaaa
     2581 gaaaatgttt atgttctcaa aagaagaact acgaaagcta ggagcagaaa atactacccg
     2641 agaaattcga caacaaccgg aactgtggca tgagacgttt gaccgttatc aagaaacagt
     2701 tgcagattta gatcgtttgt ttacggatgc gaaacaacat gctggagagc gaccaatccg
     2761 agtcattttt acaggggccg gaacctcgca atatgtggga gatacactaa ttccgtttct
     2821 tactagtcaa ggaaatacga accagtttat ttttcaaagt attggttcga ccgatatcgt
     2881 tgctacgcca aaagaatacc tgattcctga tgagacaacg atcttggtct catttgcccg
     2941 tagtggaaat agtccagaaa gtctagccgc agttaagatg gccaatcagc tggtcaacaa
     3001 gatctatcat atcgtgatca cctgtgcacc agacggatta ttggctacac aaatgcctac
     3061 aaaaaaagaa aatctagttt tactaatgcc aaacaaagcc aatgacgctg gttttgctat
     3121 gacaagcagt ttcagctgta tgacgctgac tgcgctactt atttttgatc aagcaagcaa
     3181 tcagcaaaaa gaaagatatg ttcatcaatt aagccgacta ggagaagaag tcatccaacg
     3241 agaatcagag atccaagggt atctggcatc agactttcat cgcatcattt acttaggttc
     3301 gggaagttta ggcggattga ctagagaagc gcaattaaaa gttctcgagt taactgctgg
     3361 aaaaatcgca accgtatttg atacatcttt aggattcaga catggtccca aatcttttgt
     3421 caatgagcaa acattggttt tcctgtttgt cagcaatgac tcatatacgc agaaatacga
     3481 tgtagacatg ctggaagaaa tcaaaaatga cggtattgcc caacgcgttg ttggaattgg
     3541 tcaaaagggt tcattgttta gtggtgattc ctttgaatta gttgcagatt cgttactgcc
     3601 ggatggctat cttgctttag cagatatcat ggtagcccaa acgatcgcat tactttgttc
     3661 ggtgaaggtt ggtaatacac cagatacacc atcgccaagt ggaacagtca atcgtgtggt
     3721 caaaggcgta acgatttatc catatgaaaa ataggaaaga gtgtgaagca tgttagaatg
     3781 gtcggaaaat aaaagacaag caatggaacg tctatcgacg ccagaaggca ttattaccgc
     3841 tttggcgatc gatcagcgag gcgcgctgaa gaaaatgatg tcggctttag ggatggaagc
     3901 gacaaaggaa aaaattgagc agtttaaaac actaatttcc caagaattga ctccttatgc
     3961 ctcagcaatt ttattggatc ctgaatacgg actgcctgct gcacagaagc gtgcagcagc
     4021 gagcggtctg ctgttggcat atgaaaaaac tggttatgat caaaccgtac ccggccgctt
     4081 gccggatctg ctgtcggact gttcagttct gcgattgaaa gagttaggtg cggatgcggt
     4141 gaaattttta ctgtattacg attatgaaga agcagaggaa atcaatcggc aaaagcaagt
     4201 ttttgttgaa cgaattggaa gcgaatgcat ggctgaagga ctgccatttt atttagagtt
     4261 attgtcatat gatgctaaaa atgtagatac gaaatcgctt tcctatgcca aagcaaaacc
     4321 gcgcaaagtg atcgaaatga tgaaagaatt ctcgaaaacc cagtataaag tagatgtctt
     4381 aaaggttgaa gtaccagtaa acatgtcatt tgttgaagga aatgcaacag gggagatcgc
     4441 ctatacacgt caagaagctg ccgcttattt taaagaacaa agcgatgcaa cagatttgcc
     4501 gtatatcttc ttaagtgctg gggtatcagc ggcattattc atggagacat tgcgttttgc
     4561 caaacatgct ggggcacgat tcaacggtgt actctgtggc agagcaactt ggaaagatgc
     4621 agtcgctcct tttgttgaaa aaggagaagc ggcaacttta gaatggctga cagaacaagg
     4681 gacacaaaac attcgtcaat tgaatgaagt gataagagaa actgccatcc catggtatga
     4741 gaaagtaagt gaaagcactt gttaatgttt ctaatatatt agtagtgata agagatatgt
     4801 gtgattataa tttatcatta ttgaaactgg gaggatattt tatatgaata aaagattgtt
     4861 agattattca gcttcagatt ttttgaaagc taagccgatg gaattaaagc aggcaatttt
     4921 ggcttctgaa ggtagaacaa ttatggcaga aaatgtgcca agtagctgtc cttacatggg
     4981 aaaatcagtg acaaatgcag aattggagag agctgctgga gctgatttaa ttttgtttaa
     5041 tgcactagat ctttttaatc ctcaaatttc aggtgtacct ttaactctaa aagagaatcc
     5101 aataatctgg attaaaaaag ctttaggaag agctattggt gtaaatttag aacctgtaga
     5161 caaagaagtt ttgatgagtg aaaatcgaac tgaaatttca agtggtagaa tcgtttctcc
     5221 tgagacttta aaaaaggcaa atgaattagg ctttaatttt atttgtttaa ctggaaatcc
     5281 aggaacagga gtatctaata gaactattga gaaagcaata acattatcca aatcaatttt
     5341 taatggatta attatcgctg gaaaaatgca tggtgctggt gttgatgaac caattatgaa
     5401 cttagatata gcaaaaagat ttattaaaac aggtgtagat attttattag ttcctgctcc
     5461 atacactgtt ccgtatttca tggaaagtga tttgcgagga atcgttgatt atataaaaga
     5521 ttttaataga aataaatcta ttgaggaaaa agttctagta ctaacggcta atggaacaag
     5581 ccaagactct tctgaccaag aaactattaa aaaaattgca ttagcatcaa aagcatgtgg
     5641 agctgatatt caacacatag gggattcttt aaatggtatt tgtcttccag aaaatatttt
     5701 tgctttgggt caagcaattc ggggatatcg tcatcaaatt attatgttag gaaaatctaa
     5761 ttatcgttaa ttaaggagga aatgaaagat gatcgacaaa gttcaaaaaa tagctgcaaa
     5821 aattagtaat caaagacatc tactagcttt aagagacagc atggctgcag ttatgccatt
     5881 aatcattatt ggttcctttt ttatgttatt agcaaatttc ccgatagaag gatttacaaa
     5941 atggttatct gaaattggag tacaatcctt tttgaacaaa gcatcagatt caacatttgg
     6001 tattattgga ttagctgtta cctactcttt gggacacaat ctagcaaaga cttatggtgt
     6061 agactcatta tcagcaggat tattatcttt gagtggatat gttttactta cacctttatt
     6121 ggatgcagat ggttctatag gatttccaac aaaatacttt ggtacctcgg gtctttttgt
     6181 tggtattatt gtagcacttg tatctacaga aattttccgg tggtttgtac ttaaaaatat
     6241 tacaattaaa atgccggcaa gcgttccacc aaatgtaagc cgagctttcg ttgctattat
     6301 tcctggcttt tttgtcgttc tactatggtt tattgttgtt gtaatttgtt ataaacttgg
     6361 aattgaaaat gttcatgctc ttattgcaga tacactcgca aaaccactat ctttactgac
     6421 gaaaacttta ccaggaatta tattggttat acttattcaa tgtttctttt ggatgtttgg
     6481 tattcatggt gcacaggtaa cggggccaat aattgaaccg ttattattgc aaaactctga
     6541 tgcaaataga attgcttatc aagctggaaa agaacttcct aacattataa cttatgaatt
     6601 cttatataac tttgtttttt ctggtggtgc aggttgttta tttgcacttg ccattttaac
     6661 atttttcttt tcaaagagtc aggaaaataa aactttaggt aagttatcaa tcgctccagt
     6721 aagttttcaa gtagcagagc cccttctatt tgggtttcca actatattaa atataaaaat
     6781 gttaattcca tttgtaactg caccagtagt aacaacatta attacttatt tttcaatgag
     6841 tatgggatta gttgcaaaac ctgtaggagc aacaatccca tggacaactc caccgataat
     6901 tgccggattt ttagcttctg gtggacgaat aagtggtgca gtgattcaag taataacaat
     6961 tgcaataaat gttttgatat actatccatt ctttaaatta gatgataatg ccaagctaaa
     7021 aagcgaaaaa aatgattaga actacctata tgtttctaac tgtagttaag tatgaaaaga
     7081 ctatttttaa atttagcatt tttgcgctat cggcgtagat gaagtatcac gataacgaaa
     7141 ttagtttctt tcatttag
//
LOCUS       DADVXM010000101         7032 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.107, whole genome shotgun sequence.
ACCESSION   DADVXM010000101 DADVXM010000000
VERSION     DADVXM010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.107"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(543..1559)
                     /gene="tsaD"
                     /locus_tag="KB927_002413"
     CDS             complement(543..1559)
                     /gene="tsaD"
                     /locus_tag="KB927_002413"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBB6841301.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(1556..2020)
                     /gene="rimI"
                     /locus_tag="KB927_002414"
     CDS             complement(1556..2020)
                     /gene="rimI"
                     /locus_tag="KB927_002414"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBB6841302.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2027..2569)
                     /gene="rimI"
                     /locus_tag="KB927_002415"
     CDS             complement(2027..2569)
                     /gene="rimI"
                     /locus_tag="KB927_002415"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBB6841303.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(2553..3275)
                     /gene="tsaB"
                     /locus_tag="KB927_002416"
     CDS             complement(2553..3275)
                     /gene="tsaB"
                     /locus_tag="KB927_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBB6841304.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(3466..4446)
                     /locus_tag="KB927_002417"
     CDS             complement(3466..4446)
                     /locus_tag="KB927_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6841305.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(4470..5954)
                     /gene="galT"
                     /locus_tag="KB927_002418"
     CDS             complement(4470..5954)
                     /gene="galT"
                     /locus_tag="KB927_002418"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBB6841306.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(5966..6955)
                     /gene="galE"
                     /locus_tag="KB927_002419"
     CDS             complement(5966..6955)
                     /gene="galE"
                     /locus_tag="KB927_002419"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBB6841307.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
BASE COUNT         1901 a         1544 c         1248 g         2339 t
ORIGIN      
        1 atttatcagg gtcactgctt attttcctcc ctaaaacttc tgaaagatcc ggcagtttta
       61 gatcactggg caagactcaa agattttcta tgtgtgtttc agttatgtaa tattcactgt
      121 ttgcaaaaaa tactgataga ttaactagag gaagcgtctt gtcctcatcc gacctagatt
      181 attcgatatt cctcgacaat aaacgattaa tcagtgaggg caatcagagg aacggataat
      241 gatgaataag ctgtaaaaaa tagggctttg acaaaagcgt gtcacagccc ttatttcgat
      301 taaacggtgt gtacctgtca actcttcggt cacaagtcat aatgttcata aacatgagga
      361 gctgtttttt gaaattgttc cttgtgaatc agagttaaac gacaggctta cgaactcttg
      421 attaaacggc gttcaaaagc ttgcatacgc ggtaataaga acagccaggt caaaaacatg
      481 agaagccgtt tttcctgggc tgttcttatt acttgatgca gggcagattt ttcacaacct
      541 ctttattcag ataaaaccaa gcttggatca gcattcaact gatagctagc aaaatttctt
      601 ttttgcattt ccacatgtgc tgctgctcca atcattgcag cattatctcc acaaagtcga
      661 agagggggaa tcactagttc tacctcaggg agtttagttg ccaaagcatc ctgcaatcct
      721 tcacgcaacc cttgattggc cgctacacct ccagctacaa tcagttgctt gactggataa
      781 ttttgacaag ctcgaagtgt tttagtaatc aatacatcga tcacacttgc ttgaaagcta
      841 gctgctaaat catttttgtc tagatcttct ccacgctgtt gtgcattatg caccaaattg
      901 ataaatgcac tttttaatcc gctaaaactg aaatcataat tatcttcatg gatcatcgct
      961 cgtggaaaat ggtaattatc ttttccctga tgagctagct gatcgatttc ttttccgctt
     1021 gggtaagaaa gacctaatac tcttccaact ttgtcataag cttctcctgc tgcgtcatct
     1081 cttgtctccc caatgatttc atatgatcca tcttcttgca tatagactaa ttctgtatgt
     1141 cctccgctaa caagaagtgc catcaatgga aactggaatg gtttaaccag acgggctgca
     1201 tagatatgcc ctgccatatg gtttacagga ataagcggca attggtgtgc ccaagcaaaa
     1261 gccttagctg cagaaatacc aatcagcaac gagccgacaa gtcctggtcc ataagtgaca
     1321 gcgactgccg ataaatcttc tgccgacaca ccagcttcta ccagtgcatc ttccaagcat
     1381 aaggtgattt gttctacgtg atggcggcta gctacttcag gaactacgcc accaaaacgt
     1441 ttatgactgt ttatttgaga agcaacgatg ttagataaga tctctgttcc atttctaacg
     1501 accgctacac tcgtttcatc acaacttgat tcaatcgcca gaatcaattc ttcattcatt
     1561 tcatcgtctc cgtttttaac tttctgctca taatgatcgc atcttccgtc ggattgcgat
     1621 aatatgattt ccgtttacct aatatacgaa acttttctga ttcataaagt tttcttgctg
     1681 cttcattaga tagacgtact tctaaaaaaa catgcagcga atcttttatt tgttccgtaa
     1741 tcagtaattg taacaaatgc cgtgcatgcc cttttccttg ttctgaaact gcaacagcaa
     1801 tatttgtgat ctcgacttca tctattactt tcgagtatcc aataaagcca cagatctggt
     1861 tatcttcaac taaaagcaga taatcagagt gaggctgttg gatgtctgcc aaaaactgca
     1921 ttttcgtcca aggtgaacca tgtggataag cattttcgct aatcatccat acgcattctg
     1981 ccaagtacgc ttcatcaaaa tctttttttc tgcaaatcaa ctaatctcac tcattttcta
     2041 aaagttttat catatccaac gcatcttctt ttgtttcagt gtaatatctt tttttgatcg
     2101 ttgttgcttg aaaacctaac ttccgataaa gtctttgtgc atcttgatta ctcatacgca
     2161 cttctaatga catcgtctca cagcgattca ttatagcaaa gttctcgatt tcgtcaataa
     2221 gcagcgaacc gattcgttta cgctgatatg ccggtcgaac ggcaatattc gtgatatggc
     2281 aatctaaacc gaacgctctt gaaccgataa aaccaatcat tcttccatta tcaaagatac
     2341 ctagatatag atgaggaagc ggtgacttca attctgatat aaaggcactt tttgtccatg
     2401 gcaattcgcc attatagact tctcgttcga catccagcag ctctttgata tcttctgtag
     2461 tcaattctct tagtacgtaa cgacgatcga tttgttcgat tgttttttct gtataaatca
     2521 ttttatcttg aaaaaagctt ctggcatacg ctctaaattt tttcaacata actttcgtct
     2581 ccaggtgtgt gcgtctccaa ccatttttct tctgcttcta cccgttttaa atagcgagga
     2641 agaaaagctt gtttctctgc aactggttca gctaaagcac ctaattgagc cacagttaca
     2701 ccacttggaa tatcccatgc tggaactgta ttaatcatcg cactaggcaa tatttccttt
     2761 atttcataga agaatttgtg acaatcactc ccgacgaaat aaatagcttc attcagcttt
     2821 tgtagttgtg tgaacaaatc agaagcagaa atatgtacat cttcaagtac aatttctaat
     2881 ctattttctt tccagcggta tgccccagcg tatacatttt ttcttcgagc atcaaacatg
     2941 ggcacaataa ttttatccac accgatgcaa ttagccgcga tggttttcag actagatact
     3001 cctactagct ctttatctaa tgtataagca atcgtttttg ctgtcgttac acctatacga
     3061 agccctgtat aagaaccggg accatcagaa accgcgattc ggtcaatgtc ttttggactt
     3121 atttgaagat ctgcaaacaa ttggtcgatt gcaggcatca gtgttacact gtggttgcgt
     3181 ttgatatttg tttgtatttg tccaagaatt tgttcgtctt ctaccacacc gatcgccaaa
     3241 gtttggtttg cagtatctat tcctaatgta atcatatatt tgatcctttc tgctatgaca
     3301 ttctcgcctt ccattgtagc atactttttt attctgagga tgaaaatacc aaaggcaaaa
     3361 ctagtacaat gatacatgat tatctgctgg cgggcaaatt ttgccccttc ctgaaacaca
     3421 aaaaagctgc ggtatcactt catttcccca cagcttttcc atcttttatt tcgttgattc
     3481 tcgaataatc aactctgttt ccacaataat ctttcttgaa accggtgctt tggaattact
     3541 taattgaaga atcgtctcca ctgctagctc tcccatccat tcggtataaa cttttacagt
     3601 agaaagagag ggcgttacat atttcgctac actgacatca ttgaaaccca tcacagaaat
     3661 atcttctggt accactaaac ctttttcttg aatcgctttc agtgcgccaa tcgctaatgc
     3721 atcattagct gcaaaaagcg catcaggaac atgcggattc gtttttaaat actgcttcac
     3781 tgcttgatat cctgactcga cagaaaaatc tgcttcgata attggacctt cgtcgtagcc
     3841 tttttctgcc aaaacttgtt gaaatgccat aattctggga tcttttagcc gctgatggtt
     3901 tttcttcgta tattctgttc cagcaagcat agcgatatgt tgcgctttat gggagacaaa
     3961 atgttcaatg actttttgaa cacttgactt aaagtcgaca actagagagt cgattccttg
     4021 agaagtgccg tcagaatcta ccaaaagcaa ggcattttgg gatcctttca tttctaataa
     4081 ctgagcttcg tcgaattttc ctagtgcgat cgttccatct gtcggaagat cactaatgga
     4141 atcccacgtt tctttcaata aagtaacgtt tgcttcttct gccttttttt cgattcctag
     4201 acgaatagat aaataataaa gatcttcaag ctcttccgta tcgtcgtacc actggatcag
     4261 gcgaagcgtt tgcttagtat ttgctgcatt tttacgatgt ttcgtataat ttaagcgttc
     4321 tgctgcttca aaaatttttt gctttgtggc taagccaacg gaaagatcag gatcatagtt
     4381 gagaactctt gaaacagtag caggagaaac tcctgccaac tgcgcaatgt ctttaattgt
     4441 tgccatttgt ctctcctcct tttttacgtt tataaaattg cagtaaatcg ttcaaacgct
     4501 gcctgtcctt tttcatctcg cttgaatact ccagcgtctt ccagtacacg tgcaaaaacc
     4561 tgacctacag atttttgtac gacatcggtg accgtatctt tcgtcaaatc aggatgttct
     4621 ttttttaatt gttctgccca cggacgatga tattcagcca tctggttttc ttctcctaat
     4681 aagaaatgct ctacttctac tagttctggt ttcaaacgag gtggtaaaac agcaagcccc
     4741 attacttcga tcaacccaat gttctccttt ttgatatgtt ggacatcttt atgtggatga
     4801 aaaatcccat caggatgttc ttctgaaaca ttgttgtctc gaaggacaag gtccaactca
     4861 aagtaattgt cccttcttcg tgcaattggc gtaatcgtat ggtgtggtgt accatctgct
     4921 gaaaaagctc tgatagatac tgtttcatcc gaatatgctt tccacttttc caatactgag
     4981 ttagctgctt caatcaacaa ttttttctct gttgattgca aacggatcac agacatcggc
     5041 catttcacga ctcctgcgat gacttgcgga taatctgcta gtttgataag tttttctatc
     5101 ggtgcttttg ccataggaaa ttcatgacgt cctgcctgat aatgatcatg agaaagaatc
     5161 gatcctccaa caatcggcaa gtcagcattc gaaccaacaa agtaatgagg caagacttca
     5221 gtaatccgaa gcagtctagc aaatgtttcc tttgtgattt tcatcgggcg gtgttgttct
     5281 gataaaatga tcgaatgttc attgtaataa gcataaggag aatattggaa tccccagctt
     5341 tcaccgtcta gattcattcg aataatccgg tgattggtgc gggctggata gttcaagcga
     5401 cctctatatc cttcgttttc catgcaaagc atgcaggtag gatagtctac ttttaccgcc
     5461 tcgcgttctg ctgcgatttg ttttggatct ttttctggct tagataaatt gattgtgatt
     5521 tccagttcac catactccga ctctgccgga aatttgatgt tttttgcgat ggctcttgtt
     5581 ttgatgtagt catttttctt acttaaatta aagaaatact cagttgcttc ctctgggctt
     5641 ttcgaatagt gctgtgcaaa gaatgcattg acgactgaag gtggcggtgt gagaaaatcc
     5701 attaattgcg cttcaaaaat ctcttgttct gctggcaatt ctgaaagaac accattttct
     5761 cttgccttag cgacaagctg atccaataag tctacagatt cttccttaac tggtcttact
     5821 tcaatgcttt ctagagcatc ttctcctacc atccctaaaa gacgattctg taaatataag
     5881 cggtccattt ccatccatcc gccagcttcg atcgcaagtg tggcaaaatc acaaatcgtt
     5941 tgactgattg acatatctca ttcccctatt cttcataacc atttggatgg ctgacatgcc
     6001 aatcccatgc tgttttgata attgctttga tatctgtgta ttcaggtttc caacccagaa
     6061 cctctctcgc tttttcactt gaagcgacta atcggctagg atctccagct cttcttggtg
     6121 ctatttctgc tggaatttct tttcctgtca cttctctagc tgcttctagc atttccttga
     6181 ctgagtatcc tttgctgctg cctaaattga agaagttgct ttcatttcct tctttcaagt
     6241 attccaaagc taaaatatgt gcagcaatca aatcttctac ttgaacataa tctctgatac
     6301 atgttccatc tggtgtatca taatcgtctc cataaacagc caatgctttt ctttgaccaa
     6361 gagctacttg taaaatgatt gggacaagat gcgtttctgg tgtatgatct tctccgatag
     6421 atgcatctgc ttttgctccg gctacattga agtagcgcaa agcgacatag cgcatgccat
     6481 atgcttggtc acaccacttc atcatttttt ccatcatcaa tttactttca ccatacggat
     6541 ttttaggatt agctggtgta tcttctgtga ttggagactc ttttggttct ccgtaagttg
     6601 ctgcagtaga agagaacacg attttattca cattgaactc gtgcatgact tcaagtaaga
     6661 tttgcatacc gtatacgttg ttgttgaaat acatcaatgg tttttcgaca gattctccta
     6721 ctaaagagct tgcagcaaaa tggattactc cttcaatcgg ttccttttca aatacggaac
     6781 gtagaaattc tttatcccgg atgtctcctt cataaaaatg agcatctgga tgtactgctt
     6841 gtttgtgacc tgtgagcaaa ttatctacca cagctacttg ataccccttt tgaactagct
     6901 ggtctacagc gtgcgaaccg atataaccgg ctccgcctag tactaaaatt gtcataaaaa
     6961 acactccttt gattagtaaa attgtgtttg ttgattatat ataatttaaa aaaacgaagt
     7021 ttacttttat gg
//
LOCUS       DADVXM010000102         6626 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.108, whole genome shotgun sequence.
ACCESSION   DADVXM010000102 DADVXM010000000
VERSION     DADVXM010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6626
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.108"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..894
                     /locus_tag="KB927_002420"
     CDS             <1..894
                     /locus_tag="KB927_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBB6841308.1"
                     /translation="EETIEEISKKCGHKTTINRSASSKHLDTDSSVTSSAEQERVITV
                     ERASQLIEGEQIILRNLHRQDTKRNKIRPFPIFNTKETNMPYRYQFLAEDFDTQRDIN
                     EIDIACEHINLSLQDNQIPYARFIKDLKTRLEYSIINNIPISEEDYQDYLNLSGSQQT
                     INEEELLKLVNTEVKSQDMEGQVLSEQEMKINIYLKESQKEAIELVKVINGRLADENS
                     ADMVIKTINSQILDTPFIQSLINDSIAIHNVQESKDQIMILEQQLANAYELAVFKTKN
                     SILKNKIIKLKNAMTKLAKAI"
     gene            945..3581
                     /locus_tag="KB927_002421"
     CDS             945..3581
                     /locus_tag="KB927_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841309.1"
                     /translation="MQWLKYKWPIIVSLIIILFMAYPQRVFALPWITDNKEVLKFLTK
                     YQDYLQFTKGGFGSIVVQSLSWGLIRGAYFVCKSAENLVPQSLSLFSFVESSSLGAVY
                     QSVLNTVVVGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALILLMPTMISSGIQ
                     FAKTFYKDSTTITKADGGVAWSLIEDGVTDLVYINKNDAYDRLGKDGVQKNALKEKNF
                     FSYDFSEVITVDTAKDLEDDNKKAEYLQSRLTPDGEGNMQAVKIDDGWMSMFSDSFKG
                     GYYRFTKNTFALTLGLLSLAVAYVFSIFIIVTAILELAFKRVLGVLVFATDIETGQRS
                     KVVLSDILQCYLTVGFQGFGLSMFAMFVSYLGTGGGSSVNPFIKAVAYVCAVFVLIKG
                     SGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGNGNGSDSGEGED
                     RKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDMAND
                     TKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSNRKDGAKVENADR
                     IMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKSAEELINQKRQE
                     AKYTPEAMNREEMLRKRVEGRTGTNTDEKEALTKERIQEAKNSNTGLEKLVKENLQNS
                     TSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIGVRENLQSSSTSQ
                     PKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGFKTVD
                     VRENVQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFT
                     YEDNELFRDTLNDPNPLFDNLN"
     gene            3605..3940
                     /locus_tag="KB927_002422"
     CDS             3605..3940
                     /locus_tag="KB927_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841310.1"
                     /translation="MPAFYEVKMMYRNPKNIKQEIKLFFFYLVDLGIVAGSVMASVYF
                     AKLMPISPMMKFALYLLAFVVGVWMCVRTPNHPKERNILMLYYLFKMDRNRYHEVEFK
                     RNSRGKIEL"
     gene            3937..4554
                     /locus_tag="KB927_002423"
     CDS             3937..4554
                     /locus_tag="KB927_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841311.1"
                     /translation="MIVAESNENKLSGVFDKFLELVIPKDKDMCELLPYKKILKDGTL
                     VTNDNKYQAFFKVKTTDLTSISEDGFMRMVNKLTYLNRVYLEPYKIYSLTYPTETVNQ
                     AIYWKHRIQEAKRSLLSNNDPNLETYLKWNLKLAYDNYERVDLVSTLPELMFVICVYG
                     KTQKEVKNHADVMKQAGGRELDLQRITEGDLINVITKLMNPNTSL"
     gene            4570..5037
                     /locus_tag="KB927_002424"
     CDS             4570..5037
                     /locus_tag="KB927_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841312.1"
                     /translation="MLKHCRKGFCKVIKGKNAADLIFEWKESNLINVRGKNGSGKTER
                     VMASIDNSRPRSRALVITDEKNHYKGIRTIEKKYLTNNDLKVVDDILNIYPDFNLVVF
                     DETIPVTEIKGFYQSFSNLANKYEEVLFVWITEEDSNSKSAFFSEKNAFLHSI"
     gene            5053..>6626
                     /locus_tag="KB927_002425"
     CDS             5053..>6626
                     /locus_tag="KB927_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tra protein"
                     /protein_id="HBB6841313.1"
                     /translation="MIVSKKLARNLVSEGYDLRLVEKYQPSGGIKFDERYISTGDGYV
                     TSIAVIEFAEDVNSRWLTDIMAIPNTIATFDVCTADKEDLLHKINTSIGELDYRSTNE
                     NRTTDKTDALLDKYNLEDFAQEITKRGEVVKTVHARIFVYSDSLEELEKRISEIRKDL
                     ASVNHKAIVPQFRMKDEWMSLFQDGMEQESKLFAKKGLTVPAKNIGGGIPFHHKSLKD
                     PRGFYLGTTSTGGAFIFDPFYSTKQRRSFNGFILGKMGFGKSTLIKQLQEGLQAKNCF
                     IRGFDKSGEFEGMVKKAGGVYVDLGGGDMVVNPLQIYATVMKKDQFGNDVVDESKSFQ
                     NHITKCSNQIRFLEPEIDTATVREYTLMLQDFYIHYGILPKEWREARDDNERNQLNTN
                     ICNLPNDSYPIYGEFLKFIENQQFKIKNATPERVRSIELIKLIVTDMCTTYPQIFNGV
                     TTMPNFDTTKIVYYNIDSISKMSAPVFHCQLFTALTTIWNSALQNGKIQKENFKKYGS
                     DYYKYAQDFMVLIDEC"
BASE COUNT         2466 a          865 c         1339 g         1956 t
ORIGIN      
        1 gaggaaacga tagaagagat ttcaaaaaaa tgtggtcata agacaacaat aaatagaagt
       61 gctagttcta aacatttaga tactgatagc tcggtcacta gttcggcaga gcaagagcga
      121 gtaattacag ttgagcgtgc tagtcaattg attgaagggg aacaaattat tttaagaaac
      181 cttcatagac aagatacaaa aagaaataag attagaccat ttcctatttt taatactaaa
      241 gaaacaaata tgccgtatag ataccaattt ttagcagaag actttgatac tcaaagagat
      301 attaatgaga ttgatattgc atgtgaacat atcaatctat ctttacaaga taaccaaatt
      361 ccatatgcaa ggtttatcaa agatttaaaa acacgtttgg agtattcaat tattaataat
      421 attcctatta gtgaagaaga ctatcaggat tatctaaatt tatcaggatc acaacaaaca
      481 attaatgaag aagagctgtt aaaactggta aatacggaag taaaaagtca agatatggaa
      541 ggtcaagttt tatcagaaca agaaatgaaa attaatattt atctaaagga aagtcaaaag
      601 gaagcaatag aattagtaaa agtaattaat ggaaggttag ctgatgaaaa ttcagcagat
      661 atggttataa aaaccattaa ttcacaaatc cttgatacgc ctttcattca atctttaatc
      721 aatgattcta tagctattca taatgttcaa gagagtaagg atcaaattat gatcctagaa
      781 caacaattag ctaatgctta tgagttagca gtgtttaaaa cgaaaaattc aatactgaaa
      841 aataaaatta tcaagttgaa aaatgctatg actaagctag caaaagcaat ttagagagaa
      901 gggaagaaat attgactgaa tctattaatt ggagaaaact aaatgtgcaa tggttaaagt
      961 ataaatggcc aatcatagtt tccctaataa tcattctatt tatggcctat ccgcaacgag
     1021 tttttgcgtt gccgtggatt acagacaata aagaggtatt aaaattttta acaaaatatc
     1081 aagattatct tcagtttact aaaggtggtt ttggaagcat tgtcgttcaa agtttatcgt
     1141 gggggctgat tagaggtgca tattttgttt gtaaatcagc agaaaacctt gttccacaat
     1201 cgctaagttt gtttagcttt gttgaaagca gtagtttagg tgctgtttat caatctgtat
     1261 taaacacggt ggttgtagga ttaatgatcc tttcattgat gtttgttggt tacaagatga
     1321 ttactggaaa aggaacagtg gatttaaaat cggttggaat gaacgtagtg atgtctatag
     1381 cattaatact tttaatgcca accatgattt ctagtggtat tcaatttgct aaaacatttt
     1441 ataaggactc tactacgatt acaaaagctg atgggggcgt tgcttggtca ttgattgagg
     1501 acggtgtaac tgatttagta tatatcaata aaaacgatgc ttatgatcgg ttgggtaaag
     1561 atggcgtaca aaaaaatgcg ttaaaagaaa agaatttctt ttcctacgat ttcagtgaag
     1621 taatcacagt tgatacagct aaagatttag aagatgataa taaaaaagct gaatatcttc
     1681 aatctaggtt gacaccagat ggcgaaggaa atatgcaagc cgttaagatt gatgatggtt
     1741 ggatgtcgat gttctctgat agtttcaaag gagggtacta caggtttact aaaaatactt
     1801 ttgcattgac tttaggatta ctttcgttag ctgtagccta tgtttttagt atttttatca
     1861 tagtcaccgc tattttagaa ctggcattta agcgtgtgtt aggggttctt gtttttgcaa
     1921 cagatattga gacaggacag cgttcaaaag ttgttctatc agatattcta cagtgctatt
     1981 tgactgtagg ctttcaagga tttggattat ccatgtttgc aatgtttgtt tcctatttag
     2041 gaacaggcgg agggtcttcc gttaatccgt ttattaaggc tgtagcttat gtatgtgccg
     2101 tttttgtttt aatcaaaggc agtggaacag tcatgagata ctttggtgtt gatattggac
     2161 tcaaagaagg ctatgggcaa cttgcttctg cttttggaat gggtgcaatg ctgtttagaa
     2221 aaggatcaaa tggatttaat cgtgccaaag gaagcggaaa cggaaatgga tcagacagcg
     2281 gagaaggaga agatcgaaaa ccagaaaaga atttcggtga aactctatca aaaaaagctg
     2341 gcaaaactgg aagagctttg ggatatgccc atgaacgtgg attatcaggt ttagcttcag
     2401 atggagctac aatggctagt gaaagagcaa caaaaccatt taagagtatg cgtgatatgg
     2461 ctaatgatac taagaataag ttcaaagaag gtttagatga tggtacagtg tccgctatta
     2521 ataaaaatag caaacctatg ttagctaaaa ataaagaaga tgaaactgga aaatacgctg
     2581 attccatgcc aacacgtctt tcgaatagaa aagatggtgc taaggttgaa aatgccgata
     2641 gaattatgtc tagttctgaa cgtatgcgtg aagcaatgaa aaataatgct gaatcgaata
     2701 ataatcctgt aagtgcaatt cagcaaaaag ttcaacaaga tattgaagaa cgtaaaaatg
     2761 ctatgcacgg tcaagctaag tctgctgaag aattaattaa tcagaagcga caagaagcta
     2821 aatacacgcc tgaagcaatg aatcgtgagg aaatgttaag gaaacgtgta gaagggcgta
     2881 caggaactaa tacggacgaa aaagaagcgt tgaccaaaga aagaatccaa gaagctaaaa
     2941 actcaaatac cggattagaa aaattggtca aagaaaatct acaaaattct acaagtagtc
     3001 aaggtggtcg atcagtagat gtccgagaaa atattcaagg ttcattgaat ggtcatgtcg
     3061 gacggaatgt tgatgtaaga gagaatttac aaagttcttc aaatggtcaa ggtactaaga
     3121 caattggtgt tcgagaaaat ctgcaaagta gcagtacaag tcaaccaaaa acagtagatg
     3181 ttcgagaaaa tgtacaaaat tctacaagta gtcaagggtt taaatcagtg gatgttcgag
     3241 agaatgtgca aggtagcagt gcaagtcaac caaaaacagt agatgtccga gaaaatgtac
     3301 aaagttctac aagtagtcaa ggattcaaaa cagtagatgt tcgggagaac gttcaaaaag
     3361 atagtggaga aatgaaagaa aaaacacaaa aaatcaatat cgttgaagac agaaagtcag
     3421 cgaaaaaatt tgattcaaat catgaaacag tgattattga tagtgaaatc cgtgaaaatg
     3481 ataagggatc aaaaccaaga cgaagattca cttatgaaga caacgaatta ttcagagata
     3541 cacttaatga tcctaatcca cttttcgata atttaaatta aattaaaagc cggcatgagt
     3601 gattatgccg gctttttatg aggtgaaaat gatgtataga aatcccaaaa atataaaaca
     3661 agagataaag ctatttttct tctatttagt cgatttagga atagtagccg gaagcgtgat
     3721 ggcaagtgtt tactttgcaa aattaatgcc aatttcacca atgatgaaat ttgcactgta
     3781 cttattagca tttgtagtgg gtgtttggat gtgcgttaga acgcctaatc accctaaaga
     3841 gcgaaatatt ttaatgctgt attatctctt taaaatggat agaaacagat accacgaagt
     3901 agagtttaaa agaaatagta gggggaaaat tgaattatga ttgttgctga aagtaatgaa
     3961 aataaattaa gtggtgtttt tgacaaattc ttagaactag ttattccaaa agataaagat
     4021 atgtgtgaac ttttaccata taaaaaaata ttgaaagacg gaacgttagt gactaatgac
     4081 aataagtatc aagccttttt taaagttaaa acaactgact taacttctat ttcagaagat
     4141 ggatttatgc gtatggtaaa caaactcact tatttaaatc gagtatattt agaaccatat
     4201 aaaatttatt cattaactta tcctactgaa acagtaaatc aagcgattta ttggaagcat
     4261 agaatacagg aggcaaagag aagtttattg agtaataatg atcccaattt agaaacgtat
     4321 ctgaagtgga atctaaagct agcttacgat aattatgaaa gagttgatct agtatcgact
     4381 ttaccagagt tgatgttcgt tatttgtgtt tatggaaaaa cacaaaaaga agtgaaaaat
     4441 catgccgatg taatgaaaca ggccggtggt agagaattag atttacaaag aattactgaa
     4501 ggggatttaa tcaatgtgat aactaaattg atgaatccca atacttcttt ataaggcggt
     4561 gcttattatt tgttaaagca ctgtagaaaa ggattttgta aagtaattaa aggtaaaaat
     4621 gctgctgatt taatctttga atggaaagaa tctaatttaa ttaatgtacg tgggaaaaat
     4681 ggaagcggaa agacagaaag agtgatggct agtattgata attcaaggcc tagatcaaga
     4741 gcattagtaa taactgatga aaaaaatcac tataaaggca tacgaacgat agaaaaaaaa
     4801 tatttaacta acaatgattt aaaagtagta gatgatattt taaatattta tcctgatttt
     4861 aatttagttg tttttgatga aacaattcct gtgacagaaa taaaaggatt ctatcaaagc
     4921 ttttccaatc tagcaaataa atatgaggaa gttctgtttg tttggattac agaagaagat
     4981 agtaatagca agtcagcgtt ctttagtgaa aagaacgctt ttttacattc tatttaaaaa
     5041 ggagaattga acatgattgt aagtaaaaaa ctagcaagaa atctagtaag tgaagggtat
     5101 gacttaagat tagtagaaaa gtatcaaccg agcggtggaa ttaaatttga tgagcgttat
     5161 atttctactg gtgatggata tgtaacttcg attgctgtta ttgagtttgc agaagatgta
     5221 aatagtcgat ggttaacgga tataatggca attccaaata ctattgcaac tttcgatgta
     5281 tgtacggcgg ataaagaaga cttattacac aaaatcaata cgtctattgg agaattagat
     5341 taccgatcaa caaatgagaa tagaacaact gacaaaacag acgctttact agataaatac
     5401 aatttagaag attttgcaca agaaattacg aaacgtggtg aagttgtcaa aactgttcat
     5461 gctcgtattt ttgtttatag cgattcttta gaagaattag agaaaagaat tagtgagatt
     5521 cgtaaagatt tggctagtgt caatcacaag gcaattgttc cgcaatttag aatgaaggat
     5581 gaatggatgt ctttatttca agatggcatg gaacaagaat caaaattatt tgccaagaaa
     5641 ggcttaactg ttccggcaaa aaatattggt ggcggtattc catttcacca caagagtttg
     5701 aaagatccac gtgggtttta tttaggaact acgtcaactg gtggtgcttt tatatttgat
     5761 ccattttatt ctacgaagca aagacggtcg tttaacggct ttattttagg aaagatgggt
     5821 tttggtaagt caactttaat taaacagcta caggaaggcc tacaagcgaa aaattgtttt
     5881 attcgaggat ttgacaagtc aggtgaattt gaaggcatgg tgaagaaagc aggcggtgta
     5941 tacgtcgatt taggcggtgg tgatatggta gtaaatccat tgcaaattta tgcaacagtc
     6001 atgaaaaaag atcaatttgg aaatgatgtt gtagatgaat caaagagttt tcaaaatcat
     6061 atcactaagt gtagtaatca aattcgcttt ttagaacctg aaattgatac ggcaactgta
     6121 cgtgaatata ctttgatgtt acaagacttt tatattcatt atggaatttt gccaaaagaa
     6181 tggagagaag cgagagacga caacgaacga aatcaattaa atacaaatat ttgtaacttg
     6241 cctaatgatt catatccaat ctatggagag tttcttaaat ttattgaaaa tcaacaattc
     6301 aaaattaaaa atgctactcc tgaacgtgtc cgttctattg agctaattaa gcttatcgtt
     6361 acggatatgt gtacaactta tccgcaaatt ttcaacggag taacaacaat gccaaacttt
     6421 gatacaacaa aaattgttta ctataacatt gattctatta gtaaaatgag tgccccagta
     6481 ttccattgcc aattatttac agcgttaacg actatttgga acagtgcctt gcaaaacgga
     6541 aagattcaaa aagaaaactt taaaaaatat ggcagtgatt attataagta tgcacaagat
     6601 ttcatggttt tgatcgatga gtgtca
//
LOCUS       DADVXM010000103         6294 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.109, whole genome shotgun sequence.
ACCESSION   DADVXM010000103 DADVXM010000000
VERSION     DADVXM010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.109"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(45..233)
                     /locus_tag="KB927_002426"
     CDS             complement(45..233)
                     /locus_tag="KB927_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBB6841314.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            503..865
                     /locus_tag="KB927_002427"
     CDS             503..865
                     /locus_tag="KB927_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6841315.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            917..2599
                     /locus_tag="KB927_002428"
     CDS             917..2599
                     /locus_tag="KB927_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBB6841316.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2716..4752
                     /gene="recG"
                     /locus_tag="KB927_002429"
     CDS             2716..4752
                     /gene="recG"
                     /locus_tag="KB927_002429"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBB6841317.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4801..5802
                     /gene="plsX"
                     /locus_tag="KB927_002430"
     CDS             4801..5802
                     /gene="plsX"
                     /locus_tag="KB927_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBB6841318.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5924..6166
                     /gene="acpP"
                     /locus_tag="KB927_002431"
     CDS             5924..6166
                     /gene="acpP"
                     /locus_tag="KB927_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBB6841319.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
BASE COUNT         2094 a         1093 c         1434 g         1673 t
ORIGIN      
        1 aataaaaaac cgttcactat ctgaacggtc caagtatcat tcaattaaac gcgttcaact
       61 tttcctgatt tcaaagcacg agttgacacc caaacttttt taggttttcc gtcgaccata
      121 acgcgaactt tttgtaagtt aggtttaaca gtacgttttg ttgagttcat agcgtgtgaa
      181 cggttgtttc cactttttgt cttgcgacct gtaaagtaac aaacttttgc catggtaatt
      241 tcctcctttg ccttgatttg gagcaataga ataattcagc tcataccaga ctaacatatc
      301 atatagaatg ggaatttgca agtacatttt catagataca attgacaatt gagaagaata
      361 attgtaaatt aaacaaggtt atacctgaaa ttttgcaagg tttttgagta ctttgggtaa
      421 ctgcctttta tttcaagttg cgctatgata aaatatgata gaagaaaaat gggagttttt
      481 tacccgttaa ggaggctcat tcatggctgt aaaaattcaa acgtcagctg gaaccattga
      541 aattaccaat gatgtaattg caacagttgt tggtggcgcc gcgacagatg tgttcggtgt
      601 tgtaggaatg gccagcaaaa atcaaattaa agataatatt actgagattt tgcgtaaaga
      661 aaattactca agaggagtag ttgtccgcca agaagataat ggtattgctg tagatgttta
      721 tacgattatc agctatggta cgaaaatctc tgaagtttcc cgcaacgtcc aagaaaaagt
      781 gaaatacaat ctagaggcat tattaggcgt aactgccaat tcagttaatg tctttgtaca
      841 aggtgttcgt gtactgccag actaggcagg agactggctg gtaactcagc agtcgatctg
      901 aaggaggatt atctaggtga gtgtaacaga aataagtgca agccagttcc aggaaatggt
      961 ccaggcaggt gcgaatcgtc tgcaagtaaa tgcagaatac gtcaattcat taaatgtatt
     1021 ccctgtgcca gatggcgata cgggaacaaa tatgaatcta tctatgacta gtggagctaa
     1081 ggcagtagta gattcaacct cagaaaaagt aggagaatta gcagcaatgc tttcaaaagg
     1141 attgctgatg ggtgcgcgcg gaaattccgg cgttattttg tctcaattgt ttcgtggatt
     1201 ttctaagcaa attccagatg ttgtctcatt aaatgcttct gatcttgctg cagccttcac
     1261 tcatggagtt gaaactgcgt ataaagcagt aatgaaacca gtagaaggaa cgattttgac
     1321 agtagctaga gaagcagcga aagctggaga aaagaaagca aaaagtactg atgatgtcgt
     1381 tgaagtaatg acagctgttg taaaaggagc aaagcgtgct ttagctaaaa ctccagactt
     1441 gcttccagtc ctaaaagaag tcggtgtcgt agacagtgga gggcaaggac tgctgtttgt
     1501 ttatgagggc tttttaagtg cattgaatgg agaattccaa gcggatgaaa catatgaacc
     1561 ttctccagca gaaatggatg atatggtcaa tgcagaacat catcgcagtg tccaaggtca
     1621 aatggcgaca gaagatatcc attttggtta ctgtacagaa atcatggtaa aaatcggaga
     1681 aggacctaca gtcgatagta cattcgatta cgaagaattc cgtaactatt tagatggtat
     1741 aggagattct ttacttgtgg tcaatgatga cgagatcatc aaagtccacg tgcatacaga
     1801 aaacccagga gaagtcttga attatggaca aaaattcggt tcattagtca aaatcaaagt
     1861 cgacaacatg cgcttgcagc atgagacgat tttggaacac gatgaagaag tgaacgagtt
     1921 tgcgaaaaaa gaaataccac gtatcccgta tggtatcgta gcgatcgctg ctggtaaagg
     1981 cgtccaagag ctgtttgaaa gtttaggcgc taattatgtt atcagtggtg gacaaacaat
     2041 gaatccaagt acggaagaca ttgttaaagc gattcaagaa gtaaacgcag ataaagtgat
     2101 tgtcttgcca aacaataaga acatcttcat ggcagctgat caagcagcag aagtagcaga
     2161 tatcccagta gcagttgttc cttcaagaac gatttcccaa ggattgacag ctatgctttc
     2221 attcaatgat caagcttctt tagaagaaaa caaagaaacg atgacagaaa tgttgtctag
     2281 cgttgtgagc ggtcaagtca ctcacgcgat cagagatacc tcaattgacg gtgtagagat
     2341 caaagaagga gactttttgg gcatgatcga tggaaaaatc ctgatctcta acccagatat
     2401 cacagcaaca gcgttaagta cactagaaca aatgatcaat gaggacacag agatcgtaac
     2461 gatcttggca ggtgatgaag gaacagttga acaagcaaat gaatttgctg agaaactaac
     2521 agaaaaacat cctgatttgg aaatcgagat ccaccaagga gatcagcctg tctatcctta
     2581 tctattttct gctgaataat ttctgtgtca gaatatcttt ctaacacagt attcattcat
     2641 aaaaggcctt cggttagtga tcaggtatga tcgctgacca agtccttttt ttgttaaagg
     2701 agggaggaaa aatttatgcg ttctttagat gatccaatca ctatgctggc aggagtcgga
     2761 gaaaaaagag cagctagtct tgccagcttg ggcatccaaa cgattgaaga cttactgact
     2821 tattatcctt ttcgctacga agatattcag gaaagaaatc taaacgagat ccaggatcaa
     2881 gaaaaggtta ctttgaaagg aatcgtagtc tcgcctcctg tgatgaatcg atttggttat
     2941 aaaaaaagcc gattgcaatt tcgtatgatg caagaacatg atgtgttcaa cgtttctttt
     3001 tttaatcaac cttatctaaa agaaaaagtc attttatcgg aggaaatcgc cgtatacggt
     3061 aaatgggatg caaagcgtaa agccttgaac gggatgaaga ttttaggttc tcaaacaatg
     3121 gatgactttt cgccgatata tcacgtcaac aaatcaattc gtcaaacgac attagttgat
     3181 ctaatcaaaa aagggtttca agaatacggc acattgattg aagaaaatct gccaaacaac
     3241 cttgtggaga aatatcgact gcttgaccga gcttctgctg taagaagtat gcattttcca
     3301 aaagaccacg aagaaaacca tcaagccaaa cgacgtgtcg tttttgaaga gttcttttta
     3361 tttcaaatgc gtcttcaagg attgaaaaaa gcagaaaaag cagaaacgaa tggtttggag
     3421 atcctttatg atgtccaaaa attgaaacaa tttactcaaa agctaccttt tgaactgaca
     3481 aatgcacaaa aacgtgtaac gaatgaaatc tgtcgggatc ttcgcagtcc gcagcatatg
     3541 cagcgacttt tgcagggaga tgtaggtagc ggaaaaacag tggttgccgc gattgcgtta
     3601 tacgctaccg ttacagcagg tttccaaggt gcgttgatgg tgcctacaga aatcttggca
     3661 caacaacata tggaaagctt gcaacagctg tttgatccca atgaagtaac catcgcattg
     3721 attacggggt caacgaaagc aaaagaacga cgtgagctcc ttgaaaaact agagcaaggg
     3781 gaaattaacg tcgtgatcgg cacacatgca ttgatccaag atggagtcga atttcagaat
     3841 ttaggtctag ttattacgga tgagcagcac cgttttggcg tgaaccagcg gaaagtactt
     3901 cgtgaaaaag gctggcgacc agatgtctta tttatgacag cgactccgat tcctagaaca
     3961 ttagctatta cagcatatgg tgagatggat gtatctatca ttgatgaact tccagctgga
     4021 cgtatcccga tcgaaacacg ctgggtaaga acacctcaat tggacagtgt actggattgg
     4081 acgaaaaaag aactggcaag aggacatcaa atgtatgtca tctgtccgct gattgaagaa
     4141 tcagaagcat tagatgtaaa aaatgcagtg gaaatctatg aaaaacttcg tgaactattt
     4201 gcaccaaaat atgaagttgg cttgttacat ggtaaaatga agaatcagga aaaagaagta
     4261 atcatggaag ccttcaaaga caaccagatg cagatattag tttcgactac tgtaattgaa
     4321 gtaggggtaa acgtgccgaa cgcgaccgtc atgctgatca tggatgcgga tcgatttgga
     4381 ttggcacagc tgcaccaact tcgtggacgt gttggacgcg gaagtgatgc ttcctactgt
     4441 atcttagttg ctaatcctaa aaatgaacta ggtgtggaac ggatgaaaat catgacagag
     4501 accaccaatg gttttgtact aagcgaaaaa gatctggaat tacgtggtcc tggtgaagta
     4561 tttggcttcc gtcaatctgg tctgcctcaa tttgcgattg ctgacttggt gacggatgga
     4621 aatgttttgg aggtagccag agaagaggct gcagcccttt ggcaaataaa ggattggcag
     4681 atgcttcctg agtatcagcc tttagcgcaa agcctccaaa tagaaaatca ggataatcgt
     4741 tatttcgatt agcagactgt gctatacttt atactgatga cggaaaaagg agtggaaaca
     4801 atgaaaattg ccgtagatgc aatgggcgga gatcacgcac ctcaagcaat tgtagaaggc
     4861 gtggctttag cgcagcaaga ttttccagaa gtagaattct tactttacgg aaaagaagca
     4921 gaaatcaaga aatacttaac aaatgaaaaa aacatcacga ttatccatac agacgaaaaa
     4981 atcaatagtg atgatgagcc agtaaaagca attcgacgaa aaaagactgc atcaatggtc
     5041 cttgctgcac aagcagtgaa aaacggtgaa gcagatgctg tattttcagc agggaataca
     5101 ggcgcgctac tagcagcagg gttgttcatc gtaggacgta tcaaaaatat cgaacgccct
     5161 ggcttgatgt ctaccttgcc agtagtaggg aaagaaggtg ccggtttcga tatgctggat
     5221 cttggcgcta acgcagaaaa caaaccagaa catttgttgc aatacggtat tttaggttct
     5281 ttttatgcac gtaaagtccg aggtatcgga cgtcctcgtg tcgcactctt aaacaacgga
     5341 acagaagcaa caaaaggtag tgaagtgacg aaaaaagcct atgaactcct tcagaatgaa
     5401 acaagcttga attttattgg aaacgtagaa gctcgtgagc tactcaatgg tgtggctgat
     5461 gtagtggtca cagatggatt tacaggcaac gctgttttga aatctattga aggaacagca
     5521 atgaatatga tgaatctatt aaaatctgct attctaaatg aagggatcaa aggaaaaatg
     5581 ggcgctatgc ttttaaaaga cggcttacgt tctttgaaag cagaaatgga ttattccaaa
     5641 catggcggtg ccgttttgtt tggcttgaaa gcaccagtca ttaaaactca tggagcaaca
     5701 ggccccgatg ctgttcgcta tacgatccgc caaatccaca caatgcttga gacagatgta
     5761 gttggacaat tagtcgaaca atttgaaaaa agcgaagaat agtatttgga tatctgaagc
     5821 gatccgttcc attgaaaaaa aggtggacat tcctgaaaaa tgccagtaaa attagccatg
     5881 gtgtaggtaa ttgacaagtg tatgattctt ggaggtgaaa aagttgactc gcgaagaagt
     5941 atttaacaaa gtagcgaaaa ttatttcaaa tcattttgag atagataccg ataaagtgac
     6001 ggatgaattg aacatcaaag atgatttaaa agctgattca attagtatta tggaattcgt
     6061 tttagagctt gaagatgaat tcggtacgga aatttcagat gaagacgctg aacaaattga
     6121 aacagtcggt ggcgcagtag attatatcag cagccatctt aaataatttc aaataaaagc
     6181 aaagaaggat aaaaagctgc atgcagcttt ttatccttct ttttttaatc tttttgacac
     6241 gtaaaagtca tttttctgat aattctggcg ataaacagaa attatgttgc aaag
//
LOCUS       DADVXM010000104         6152 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.110, whole genome shotgun sequence.
ACCESSION   DADVXM010000104 DADVXM010000000
VERSION     DADVXM010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.110"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(151..1830)
                     /locus_tag="KB927_002432"
     CDS             complement(151..1830)
                     /locus_tag="KB927_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBB6841320.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(1832..2044)
                     /locus_tag="KB927_002433"
     CDS             complement(1832..2044)
                     /locus_tag="KB927_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBB6841321.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            2437..4167
                     /gene="efrA"
                     /locus_tag="KB927_002434"
     CDS             2437..4167
                     /gene="efrA"
                     /locus_tag="KB927_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBB6841322.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            4164..5924
                     /gene="efrB"
                     /locus_tag="KB927_002435"
     CDS             4164..5924
                     /gene="efrB"
                     /locus_tag="KB927_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBB6841323.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
BASE COUNT         1840 a         1105 c         1295 g         1912 t
ORIGIN      
        1 atttttttgt atgaaaaagt aaataaattt aagaggctat gaaagagcca ccttgtatca
       61 aggaataaga acaaacaaaa atggcttctc atgtttttca tttgttttct cttatattca
      121 ggacaaggtg ctgatttcat aacctcttat ttattcttca tctggtgtca ttaccattgg
      181 caaaatcatt ggatgtcttt ctgtacgttc gaataagaaa ggctgaagcg cgccagtcat
      241 cgcttctttc aatttatatt ctgaacagtc aggtccattc aaacattctc ttaaagcgtg
      301 gaataagatt cgctgagctt cattgatcat ttctcctgat tctcgcatgt agacaaatcc
      361 acgagagaga atatctggac cagccaagat ttcttttttc ttgatatcca ctgtcgcgac
      421 agctaataca agaccttctt ctgaaagcag gtgacggtca cgtaaaacga cattaccaat
      481 atcaccgatc ccgctaccat cgatatacac atctccagcc acaaaatgcc cagcaggacg
      541 cgcagaatcg ctagttaacg ctaaaacatc gccattttcc atgatgaagc agttttctgc
      601 aggaacacct acatcttgtg ctagagaagc atgtactttc aacatgcgga attctccgtg
      661 gacaggaata aaatattttg gcttcatcaa acgaagcatt aatttttgtt cttcttgtcc
      721 accgtgaccg gaagtatgga tgttattgat ttttccgtga atcacttctg caccagcttc
      781 agacagcaaa ttgatcaaat gattgacact tgttgtatta ccaggaatag gtgaacttga
      841 aaagatcact gtatcgtctg gctggatttg gatttgacgg tgagtaccat tcgcgatgcg
      901 gctcaacgcg gccatcgctt ctccttgaga acctgtacat aggatcatcg tttcattggc
      961 aggcaagcga ttgatttcgt gtgcatctac aaatgtgccg tctggaactt tgatatatcc
     1021 taaacgttga ccgttgacga tggcattttc catgcttcgt ccgaaaacag cgattttacg
     1081 accagttgcc acagcggcat ctgctgcttg ctgcaaacgg aagatgttag aagcaaagct
     1141 ggcaaaaatg atacgtcctt cgatttttga aaagatcttc aaaatagaat gcccaatcgt
     1201 tttttctgat ttagtaaatg ttggaatctc agcatttgta ctatcagata aaaggcacaa
     1261 gactccttct tccccgatac gagccatttt atgcaagttt gctggttcgc caacaggagt
     1321 gaaatcgaat ttgaagtctc cagtcgctac gatatttcca gaaggtgttt tcaccacgat
     1381 ccctaatgca tctgggatac tatgggtcgt tctgaaaaag ctgacagaag tctttctaaa
     1441 acggatgatc gtatcttcat tgatctcatg gagctctgca tctcgaagca agccatgctc
     1501 atctaatttg tttgtgatca acgctaatgc gagaggacca gcatagatag gaatatttgc
     1561 ttgtttcagc aagtagggta ttccgccgat gtggtcttcg tgcccgtgag taatcaccaa
     1621 ggcttttact ttgtgtaagt tttgtatgat gtagctgtag tcgggaatga catagtcaat
     1681 tccaagtaaa tcgtcttccg ggaatttgat cccggcatca atcaaaatga tttcatcttg
     1741 gaattgtacc ccatacgtat ttttcccgat ttcacctaat ccaccaatag caaagacgcc
     1801 tgtctcgtta tttttgatgg aaagtttcat attaaaactc cactaatgag aaatcagcat
     1861 tttctttttc gtactctaga tgacttcctt ctagaagttg aacgaattca atattgtatg
     1921 gggtattttc ttccacacgt tggcgagcgt ctacatcgct ttttgcctca atgtaaagag
     1981 attttgtttc ttcccgttta gggttgcgta cttttgtttc ttgataataa actttataga
     2041 tcattgtttt gtctccttta tctgcgtaaa gcagtgattt agctagttga tttttttaga
     2101 caacacaaaa cgaggggaca agccacctgg tttttcatat gctttgacta gaatactgga
     2161 ttcgagtcaa agagacaagc ctcgtttttg cttatctgtt cggatatttt ttcaaccgta
     2221 ccttctgtat aaaaaatata caacaattaa ttgttattct agcataaaac agcaaataag
     2281 tatagaaatc aactagattg aaagaaaaaa tcaatgttta tcatcccgct ataatcataa
     2341 tgactttttt atgagagaag tgttctatta ataggctcgt tgtgctatca tttttagtaa
     2401 tgaaaatgta acaaaagatt aaaaggagat gagaaagtga aactaatgtg gcattatacc
     2461 atgcgttata agaaattctt gtttttcaat ttcatatgcg tatttggttt tattttgatt
     2521 gaattaggac ttcctacgat tttagcacgt atgatcgatg taggaatccg caatgatgat
     2581 tttgattatg tgaagcaaca agggatattt atgatcgtta ttactgtaat cggtattatt
     2641 ttgaatatct tgttaggtta ttttggttcg aggattacga ctaatatcgt agcagatatt
     2701 cgagatgatt tgttcgaaaa gatccaaagt tattcgcatc aggaatacga aaatctaggc
     2761 gtatcttcat tgatcactcg tacaacaaac gatgcttatc agatcatgtt gttcctgcaa
     2821 aatattttac gtatcggttt tatggcacca atgatgttca ttgtcagttt gtacatggtc
     2881 atgcgtacaa gtgtgacact cagtttgtat gtagtaggtg cattaccttt actattattg
     2941 gcagtcgtag cgattgctaa ggtgtctgaa ccgttatcta aaaagcaaca aaaaaactta
     3001 gataaaatca acagtatctt gcgggaaaat ctttcaggat tgcgtgtgat tcgtgcattc
     3061 gtcaatgaaa agtttgaaga aaaacgtttt gctgtagtca atgagaatta tgcttctagt
     3121 tcaaaaagct tattccgttt gatggctgtt gcacaaccgg gtttttattt cttatttaat
     3181 atcgtaatgg tattgatcat ctggagcggg gcagtgcaaa tcgatgcagg cgagcttcgt
     3241 gtaggagatt tgattgcgtt tatcgagtat atattccatg ccttgttctc attcatgtta
     3301 tttgctagtg tgttcatgat gtatccaaga gcagctgttt cagctggacg tatccaagaa
     3361 gccctagatg ccaaaccttc gattgtagaa gatccaaatg gtatatctga tacaaaaact
     3421 aaagggtata tcgaatttca aaatgtaaca tttgcttatc caggccattc gcaagagcca
     3481 gtgatacgaa atgtcagttt tacagcctct ccaggagaga ccgttgcttt tattggaagt
     3541 accggtagcg gaaaatctac gttgatccaa ttgatccctc gcttttatga tgtgagtgaa
     3601 ggaaagatct tgatcgatgg agtagacgtg agagattatc ggctaagcaa gttgcgagat
     3661 aagattgggt ttattccgca aaaagcgctg ctatttactg gaacgattgc agataatttg
     3721 cgatacggga aagaagatgc tacgcaagaa gaaatggaac gtgcagctga gattgctcaa
     3781 gcttcagaat tcatttctcg aaaaccagat ggatttaatg aacatttatc agaaggtggt
     3841 tccaattttt caggtggaca aaaacaacga ttggcaatag ccagagccat catacgccgt
     3901 ccggaaatct atatttttga tgacagcttt tctgcattag attatcaaac ggatgcgaag
     3961 ttacgtgctc gtctgaaaaa agaaacgaca gaatctactg tattgatcgt agcacaacgt
     4021 gtgggaacga tcatgcatgc agataagatc atcgtattaa atgaaggaga agtcgtcggt
     4081 atggggacgc atcgggagtt gttggaaaaa tgcccgattt attatgatat tgccgcttct
     4141 caattatcaa aggaggaatt agcatgaaaa aaaccttttc ttccttaaaa cgtttagctc
     4201 gatatatcag accgtatcgt gagacttttc ttttagtgat cctatttaca gttctgacag
     4261 tggctttcaa cgtggctttg ccatatgtta caggacttcc tactacagaa atcagccgta
     4321 atattgccaa tggcgaatca atcaattttt cttatatatt caaatgtctc atttggatca
     4381 cagttgttgg aatagggtat tgtatttcgc aattactttc tggtgttttg atgacaaatg
     4441 tcgttcaaag tgccatgcat gatttgagaa gagacataga agaaaaaatc aatcgtcttc
     4501 cggtttcata tttcgataaa aaccagcaag gaaatatttt gtctcgtgtg acgaatgatg
     4561 tagatgcagt cagcggtgct ttacaacaag cttttattgg tatcgtaaat gcgatattgg
     4621 gaattacgtt ggctgcagca atgatgtttt atatccagcc gatgatggcg ctgatctcta
     4681 tgatcatgat tccaacatcg atctggatct caaaacgagt gatcaatgct tcgcagaaat
     4741 attttcaaag catgcagaat tctcttggtg agctaaacgg ctacgtccaa gaaaatatga
     4801 caggttttag tgtattgaaa gtatatggac gcgaaaaaga aacattggaa ggattcaaaa
     4861 aagttaatca cagcttgaaa tactttgggt ttcgtgcagc attcatttct ggcttgatga
     4921 tgcctctagt tcaattaact gcctatgcta cttatattgg tatggctgtt ctaggaagct
     4981 tttatgttat tactggggcg atcgttgtcg gtcaactaca agcattcatc caatatattt
     5041 ggcaaatcag tcagccaatg gggaacgtga cacaattgtc ttcagttttg caaagtgcat
     5101 cagcggcaac gaaacgtgta ttcgagattt tagatgagcc agaagaaaaa gaaaacaaag
     5161 tagatgcttc actgccagaa acgattttag gagatgtgac attcgatcat gtcgattttg
     5221 catatgatcc gaagaaacca ttaatccaag atttgaattt tgaagtgaaa gctggtcaaa
     5281 ccgtagctgt ggtcggtccg accggtgccg gcaagacgac attgatcaat ctattgatgc
     5341 gtttttatga cgtagacaaa ggagcaataa ggattgatgg aatcgacacc aaatcaatga
     5401 gtcgcagtga tgtgcgttcg ctatttggta tggtcttgca agatgcatgg ctttatcaag
     5461 gaacgattgc agataatatc cgcttcggaa agcttgatgc gacagattat gaagtagttg
     5521 atgctgcgaa aacagcaaac gtagatcatt ttatccgaac gatgccagat ggatatgata
     5581 tggccatcaa ttctgaggga gacaatgtgt ctttaggaca aaaacagttg ctgacgattg
     5641 cccgagcagt ggtctccgat cctaaaatct tgattttaga tgaagcaaca agttcagtag
     5701 acacccgttt agaagcgttg attcaaaaag caatggatcg cgtgatggag ggacggacaa
     5761 gtttcgtcat cgctcaccgt ttatcgacaa tccgtgatgc agatctgatt ctagtgatgg
     5821 atcaaggtca gatcattgaa aaaggaacgc atgagagttt attggcacaa ggtggatttt
     5881 atgaaaaact gtataacagc caatttgctg aggaagcaga ataagtcata taagaataaa
     5941 acagtttaaa acttattttt tgttctctat tcttgataat ggtaaagtaa agttatcaag
     6001 aaaagtgagg acacggagat ggaacagttt ttaaatgaaa aaattactga agccaaaaga
     6061 gaagttgatc gtttaacgca cgtctgtcag acgaagcctt ttgattcagc tgattttttt
     6121 gaaaatgagt ttcaaatcga acgcttggca gc
//
LOCUS       DADVXM010000105         5908 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.111, whole genome shotgun sequence.
ACCESSION   DADVXM010000105 DADVXM010000000
VERSION     DADVXM010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5908
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.111"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            43..113
                     /locus_tag="KB927_002436"
     tRNA            43..113
                     /locus_tag="KB927_002436"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:75..77,aa:Cys,seq:gca)
     gene            134..218
                     /locus_tag="KB927_002437"
     tRNA            134..218
                     /locus_tag="KB927_002437"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:168..170,aa:Leu,seq:caa)
     gene            280..352
                     /locus_tag="KB927_002438"
     tRNA            280..352
                     /locus_tag="KB927_002438"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:313..315,aa:His,seq:gtg)
     gene            362..433
                     /locus_tag="KB927_002439"
     tRNA            362..433
                     /locus_tag="KB927_002439"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:394..396,aa:Gln,seq:ttg)
     gene            451..535
                     /locus_tag="KB927_002440"
     tRNA            451..535
                     /locus_tag="KB927_002440"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:485..487,aa:Leu,seq:caa)
     gene            790..1665
                     /locus_tag="KB927_002441"
     CDS             790..1665
                     /locus_tag="KB927_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6841324.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            1769..2533
                     /locus_tag="KB927_002442"
     CDS             1769..2533
                     /locus_tag="KB927_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBB6841325.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            2520..3962
                     /locus_tag="KB927_002443"
     CDS             2520..3962
                     /locus_tag="KB927_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6841326.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            3973..5304
                     /locus_tag="KB927_002444"
     CDS             3973..5304
                     /locus_tag="KB927_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBB6841327.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            5317..5775
                     /locus_tag="KB927_002445"
     CDS             5317..5775
                     /locus_tag="KB927_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6841328.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
BASE COUNT         1942 a          900 c         1257 g         1809 t
ORIGIN      
        1 ctataattta ttctttattt tatagattga taatagtata atggcggtat agccaagtgg
       61 taaggcagag gtctgcaaaa ccttcatcac cggttcaaat ccggttaccg ccttagtact
      121 aataaatcaa cttgccggcg tggcggaatt ggcagacgcg ctggactcaa aatccagtgc
      181 ccgttgaggg cgtgccggtt cgaccccggc cgccggtatt gactaagatg tcttcatctt
      241 agttttttat tgagaaatta aataacatct tttatgatgg cgaatgtggc gaagtggtta
      301 acgcaccgga ttgtggctcc ggcattcgtg ggttcgattc ccatcattcg ccctttattc
      361 ttggggtata gccaagcggt aaggcaaggg actttgactc cctcatgcgt tggttcgaat
      421 ccagctaccc cagttattat ttttaaattt gccggcgtgg cggaattggc agacgcgctg
      481 gactcaaaat ccagtgtccg ttgaggacgt gccggttcga ccccggccgc cggtataatt
      541 atcaatatag caactttctt atagagagtt gctatatttt ttttgttttt atgtaattac
      601 ctccaaatca attcgataca agtattatca taaaacgagt aaaaaagata ttgataacgc
      661 ttttattatg tgttaaacta tttttgtaaa ttatgtaggg tgctactatt caattaggca
      721 cgacctaaga aagggttctt tcttaggtcg ttttttgtct ttaaaaattg tttggagaca
      781 aaaatatgta tgaaggagtc tgcaagttgt tttgttttat catatagagg aggtgaatta
      841 acggtgtatg tgatgaaaaa gctgaatcat aatgctgtat tgatcgatga cgatggaata
      901 gaaaaaattg cgatggggaa agggattggc ttttctgcta aagtgagtaa gccatttgat
      961 gttgaggatg ctgacaaatt atttgtatta gattctaaag aaaagatcaa acgattcagt
     1021 gagatagtct cgcagattcc aatcgaattt atggattttg cggaagaagt gattgaactg
     1081 ataacagcta ggatctcctc tccattagat tcaaatatct atattacatt gacagatcat
     1141 atttattttg ctattcaacg aaaaagagaa gatagagatg tcacagcaat tatgttgcca
     1201 gaaatgagat tcctttatcc aaatgaatat gatatagcag tagaagtggt cgagcgaatc
     1261 aatcatcgat atcaaaccga gttagggtca aatgaagtag gattcatcac tatgcatatc
     1321 attaatgctg agctaggaga gcctaatagt ttaaagagct taaaaatagt agaaatgacg
     1381 accacgattt tgtcccatct agaaaaatcc tattcaaacg tttatgataa agaatcactg
     1441 acttatcatc gcttaatggt tcatatcaaa ttcctggtta aacgcttgat ttatcaggaa
     1501 gaaacgccag tagaaaatat tggttttttt actgaaacat ttaaacatag caaagcgtat
     1561 tgtacagcac taaagattaa agatatcatc gaacagcaat ttcaacttgc cattcaagaa
     1621 aatgaaatca tctatttggc aattcatcta gcaagaatct attaaaataa gggcgtaact
     1681 atctataggc gcaaccaaat gacacatagt aaatggacta tgattatttg gttgcgccta
     1741 ttttagtaga aaaaagaagg agaatgaaat gggaaaagtg atttttaatt cggatgattt
     1801 tggctatagc catggtgtga attatgggat tatggatgct tatcagcgag gaattttgac
     1861 atcaactaca ttgatggcaa atatgccggg tttcgagcat gctgtgaaac taagaaagga
     1921 aatgcctagg ctaggtgtag gagtccattt aacattgacg tgtggcaaac cactcctcaa
     1981 aactgtcgat actcttatcg aaagcggaga gttcagatcc ttatcttatt atcagcatcc
     2041 atttaacatt gacaaagatc aactgtatca ggaatggaat gctcagattc aaaaaattta
     2101 tcatgcgggg atcataccaa ctcatttaga cagtcatcat catactcata ctttggatga
     2161 aaatcaggag gtagttgtta cattagcaaa aaaatatgat ttgccggttc ggagcaactt
     2221 tgaacgaaaa gatgaagttc gtcatgtcga ttattttgag ccttgtttcg atgtcgtagg
     2281 agaaactgat gaaaaaaaac gacaaatcaa tacgagtgtg gaagaatatt tggcaagttt
     2341 actcatgata ttgagagaag ataaaacgat cgaagtcatg tgtcacgcag cgtatttgga
     2401 tcaggaattg ttaaatggtt caagttttgt gtatcctcgt acccaccaag tcgaattttt
     2461 aattcattca gcatttgctc aaaaagtgaa aaatgatcct ttgattgagt tagtaacata
     2521 tgaggatatt taatagagga ggaataaaaa tgaatgttaa atcaaatgtg cagaagcttg
     2581 gaagagcgat gctacttcca gttgcagcga tgccattagc gggattgatc atgcgtttat
     2641 cagctgacga tatgctgaac atcccagtaa ttggtgcagc tggaaatgcc gtttttggaa
     2701 acttggatat cttatttgct ataggagttg caatcggttt tgtcaaaaat aaggacaaag
     2761 gaatacctgc acttactggt tttttagcga ttgctacctt gaaaaaaggc ttagaaatta
     2821 tggacccaga agtgaatatg gggatttttg gtggaattat ttccggttta gtagcggcat
     2881 ggacgtataa tcgctttaaa gaacaaaaat taccagtagt tttttcttat tttgcgggcg
     2941 aaaaattccc attgactatg gtgatgattc tacaaacaat cgcagctgtt tttttgggct
     3001 ttatctggcc gctcatccaa attgggattg ataattttgc aaaactgctc gttgatatgg
     3061 gagcattagg tgtggggata tttatgtttt tgaatcgttt gctgatcccc tttggactgc
     3121 accatgtgtt gaatacgtat atttattacg atttaggaag ctatacatct cctagcaagg
     3181 aagttttcag aggagagatg acacgcttta tcaacggaga tcctcaggct ggactgtttt
     3241 tatcaggttt ttttgtagta atgatgtttg gtataccagc tatatgtcta gctatctata
     3301 aagcagctta taaagaaaat aaagagatgg tcaaaggaat catgggaagc ggtgcaggaa
     3361 cttcatttat tgcaaatatc actgagcctg ttgaatttag tttcatgttt ctttctccta
     3421 tgttgtacgt gatccatgca ctttttgccg gtttagcagg gattgtctgt tacttattca
     3481 atatacgaat tggttttaca ttcggagcat gtattgttga ttatctcatc aattttcgaa
     3541 tcgctaccaa tgctattttg attcttccaa tcggaatttt cttttttgcc ttgtattacg
     3601 ttacttttta ttatttgatc aataagagaa acattcagac attaggacgt gaagctaagg
     3661 cagagtttgg caatgaagta accttagaag aaacagagtt agggttagca agtaaaaatt
     3721 atgaatatat ggcaacaaaa atgctacaag cgtttggagg aaaagccaat atcctggatg
     3781 tctatagttg taatacacgc ctacgggtag aggtagtgga tcccaccatg gtcgaggaac
     3841 agcgaatcaa gcaattaggg ataagcggga tcattaaacc aactgaaaaa aattatcaaa
     3901 ttatcatcgg cttagaagtg acttatgtta tggcagaatt caataaatta ttagaagaat
     3961 agaaaggaaa agatgatgat gaaaaaacag attatcacta tagctggagg cgggagtacg
     4021 tatacaccag gaatcgttca agccattttg aacaatgaaa aacggttgcc attatctgaa
     4081 atacgtttat atgatattga tgaagaaaga aatatggata tgtacttgat tgttaaattt
     4141 atgctgaaaa gaaaaggttt ttcaaatatt cgcattcgtg caacggatga tccaaagctt
     4201 gcttttacag gatgcgattt tgttttctca caaattcgtg ttggaggatt ggagatgcga
     4261 gaaaaggacg aaaagattcc acttaaacat ggattagtag gacaagaaac gtgtggactc
     4321 ggaggatttg cttatgggat gcgctcaatc aaaggtttat tggaaattgt cgatcatata
     4381 caagactatg cccccaaagc atggattttg aattatacaa atccagagtc gatcgtttct
     4441 gaagctgttc gtcgtaaata tccgaatgta aaaatgatta atgcctgtga tatgactatt
     4501 tcaattgaag aaacgattgc agtgaattac ggttatgatc gtaagaattg gatcgttacg
     4561 tattatggtt taaaccactt tggctggtat acatcgattt atgataaaga attgcaacga
     4621 gaaattatgc cagagattat tgaaaaacta ataacaaaag aaatgcaagt cgccgatttt
     4681 aatataggag ataaaacttg gcaaaaaacc tttcaaatga tgtcagtcat cacgaaaaat
     4741 tttccaagta atatcccgaa taattactta gagtattact tatatcctga tatggtcgtt
     4801 gagcatactg acaaagagta tacacgtgct aatatggtca tggatggacg agagaaaaat
     4861 accaaagaaa tggctgataa aatacgccgc ggtattgtgg aagaagtatt gaactttaat
     4921 tttggggagc atggacaata tatcgtcgat atagctattt ccttgttgaa tgatgatcgt
     4981 cgtcgcttta tgctaatcgt tcctaatcaa ggggcgattc cgaatctacg gtcagatgca
     5041 gttgttgaaa taccggcata tgttggtgca actggtgtgg agccaattac actaagaaaa
     5101 ccaatcagtg attttcataa aggattgatg gaggcacaag ttgcagtaga gaagttacta
     5161 gtagatgctt actttgaagg ttcttatcaa aaagctttac aagcatttac attgaatcaa
     5221 accgtaccaa atgccagagt cgcaaaaaaa atactagatg aaatgatcaa agtaaacaaa
     5281 aaatattggc cagcattaaa gtagaggtga taaaaagtgc atttctttaa aacaagaaac
     5341 attctaaaag ctgtagctag tggtcaaatt attccattaa cagcagtaaa agacgaggtc
     5401 ttttcttcaa aaatgatagg agttggatac gctataacga atcatgatgg atatatccat
     5461 gcgccagtta aaggaataat cgataatata tttcctaccc gacatgccat aacgatcgaa
     5521 agtgaatctg gcagaaaaat actgatccat atgggtttag atacagttga actcgaagga
     5581 agtccgtttc agatacgggt tgaaagtaac caggaggtaa aagaagggac actgttagct
     5641 attatagatt tgaagaagtt ggagcaagca caaaaagata cggtgatcat tgtagtttct
     5701 ccaggcattt ttgaaggaaa tttattaaaa caaaaccaag aagtaaagat taaagatagt
     5761 tgttttgaat tttagtgtac gatgaaaaaa gttaaatagg gtgatattta tgggtgaatt
     5821 tacaaaattt ttttgaaatg atatgtttca atcactagat ttaatcattt tgatttttgt
     5881 taattatcga atttttttgt tgctccta
//
LOCUS       DADVXM010000106         5726 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.112, whole genome shotgun sequence.
ACCESSION   DADVXM010000106 DADVXM010000000
VERSION     DADVXM010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.112"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            196..921
                     /locus_tag="KB927_002446"
     CDS             196..921
                     /locus_tag="KB927_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841329.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            911..1420
                     /locus_tag="KB927_002447"
     CDS             911..1420
                     /locus_tag="KB927_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841330.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1490..2938)
                     /locus_tag="KB927_002448"
     CDS             complement(1490..2938)
                     /locus_tag="KB927_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6841331.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2938..3654)
                     /locus_tag="KB927_002449"
     CDS             complement(2938..3654)
                     /locus_tag="KB927_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6841332.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3635..3985)
                     /locus_tag="KB927_002450"
     CDS             complement(3635..3985)
                     /locus_tag="KB927_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBB6841333.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4129..4902
                     /locus_tag="KB927_002451"
     CDS             4129..4902
                     /locus_tag="KB927_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6841334.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5073..5439
                     /gene="ssrA"
                     /locus_tag="KB927_002452"
     tmRNA           5073..5439
                     /gene="ssrA"
                     /locus_tag="KB927_002452"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         1661 a         1124 c          994 g         1947 t
ORIGIN      
        1 aaaattattg tcgctgctcc tcttttcgaa taaacagtgt tcaaaagctt gcatctacgg
       61 taatagaata gggcagcttc ttcacaacct cttgcttttt acaaaatatt ttctggtttt
      121 aattcgtgat ttcactaaag gaatttcata ctttattcat attcattttc tatacttttt
      181 atagaggtga aaagtatgaa aataatccgc tatgctactg ctcgattaat ttattacaaa
      241 aagcagacaa tactctattg tttattttca agcttttctg cttttttatt gatagcatgc
      301 ctgactcttt accattcgca atcggcttta gccaatcaag tccaagatcg gctttcattt
      361 attggcgctt ctgcatctac agagcttctt ccggctttag aattagctag ccgattttat
      421 ataaaaggca tattcagttt attttttcta tttgccttcc tttttatctt tttcttttac
      481 tattcagtca ggcaaaacaa gcaggaattg atcaattggc gcctgactgg tctttctaaa
      541 accaaattat tcctttttat tttctggcag ctgttctttc ctctctttct ttgttgtatc
      601 ttggttttat tgtggatcgt cagcttccag tcagtttatg aagcgcttct tcaaaggatc
      661 aattttcttg tcttaaagac tactgaactg ccagatatcc gtgatatctt gacttcggta
      721 agcggactta caattccgat ggatcaacag acttttttta ccatcgattt ccaaaatgat
      781 ctttttttca cagatatact taagggattt gcccaaactc ttattgggct cagtggatgc
      841 tgtctcattc ttagtctatt ccctttcact ttttttatcc atcatttgca aagtaggagg
      901 cctggacgta atgaaacctg aatatttgat tcatgctgaa cacttgaccg ttattttgtg
      961 tcctctcgaa aaacagcata aaatattgga gcacttgaaa aaagaggttc ttgttgcaaa
     1021 actggataat tttgcgatca tccaaaaaaa ttggccgatg tttccttatc tgaatcttaa
     1081 agaccatgtc ctgttggatg taccggaaaa agaaatcaaa caagatcgtt tggcctatca
     1141 agaaaaactt gatatctctc cttccttgct taattgtgcg gcagctgagt tgacgtcttt
     1201 tgaaaaagta aagctgcaat tacttcatgc cttgctttcc aagcgaaaca atattgttat
     1261 tgaagataca tttgatgaac ttagtgtatt ggagatccaa gagctactcc acttgctttc
     1321 ttatttagct catgaagaaa atcaaggtat cttactcttt actcatgatg ctactattgc
     1381 tcaaagtcct tatattgatc gtttagagcc cgcgggctaa atcaatcatt ttatagtaaa
     1441 aacaagcggt atagaagatc gattcatgat cttttatacc gcttgttttt tactcttttt
     1501 tgatttctac gtcaggcaaa cgaacagcga attttgttcc ttttcctagt tcgctttcta
     1561 cttctaattt tcctttatgc aagcgtacaa gttgctgcac gattggtaaa cctaatcctg
     1621 attcaccata ttttgtattt tttcttgaag gatctacttt ataataacga tcccagatac
     1681 ttttcatttg ttgttcagac attccaattc ccgtatcttc aatcgtgatg atcgtttcaa
     1741 gatagccttt ttctaaagta atcgtgattt ggccgttttc agtaaactgt atcgcgtttt
     1801 gaataatatt gaccatgatt tggacaaatc ggtcataatc agcgtaaaca tcaatatcat
     1861 caacggcttt caatgtcaat gtatctcctg ctgcttctgc tttagcttct aactgtgcaa
     1921 caatattttt caatgtttct gttccattga attttttaat gaccatactg atttgattcg
     1981 tacggatttt ttcataatcc aagttttcat tcaccaaacg gatcagacgc tctgtttcat
     2041 ttttcatcaa tttaatcgcg ttttctcgct gattttcagg gattgcattg tattctaacc
     2101 cttccagaag tccgttgatt gtcgtaagag gtgttctcat ctcgtgagaa gcatctgcca
     2161 taaattgtct tcgacgattt tcttgttctt caatttctgc ttgagattct ttcaatgaat
     2221 tcgtcatttt attgaaatca tctgctaact catcaaattc atctttgtca tgtacgggga
     2281 gctgtacatc aaaattacca ttcgtcactt ctttcgtcgc attccttaac cgattgatac
     2341 gcttaacttg gaatgctgca aaagcatagc tggcaataac tgcaacgata ctggaaaaaa
     2401 taaatccttt gaacaggttc agtgtaattg gacgaacgct gttatcgata tttcgcgcag
     2461 gttgactaac tacaagtgct ccatagaatt catgattcaa attaaatggc acaagtgcgt
     2521 aagaggtcgc ctgtgcttgt cctaaaatat ttttattcga tgtgaatttt tcttgacgtc
     2581 cattcctcag atttttccat tgatcagctg ttaaggtaaa attcagtaaa gctgtattag
     2641 tcggataaat gacacgttcg tttttatcga taaatataaa gttcacattt tgttctgtca
     2701 gtacttgctc tgtcagcagc aatgcatttt gaaacgcctg atcttgacta aactgcggga
     2761 gcgtatcggc ataggtttgc gttgtctttt caactgattc agcatatcca aacagttgct
     2821 ggtaattgtt ttcttcaatc gtttgttttg tcagttgtgt aaaagaaact ccaacgatca
     2881 ataagatcaa cgcgaccatt ccgcaaaaag ctaagagttg ctgatacaaa taacgcatta
     2941 ggcaacacca gaatcatcga atttgtagcc gactccccaa acagtttgga tgacttgtgg
     3001 tccgaccttt tcgatttttt gtcgtaattt cttgatatgg gcgtccactg tccgttcatc
     3061 accaaagtac tgataatccc agactaattc aagcaactgc tcccgagaga atacttgacg
     3121 tggttttttt gctaaagtaa acaatagatc gaactcttta ggcgtcagtc cttcaattgg
     3181 ccggttgtcc agatacgctt ctcgtgtttt cgtattcatc ttgaaatgac tagtctcgat
     3241 atcaaaatga tcatctgaaa ctgctgcttc ttctcttgct tctgccaact cactacggcg
     3301 atgcaaagct ttcattcgag caataagcgt cagaggactg aaaggttttg tgacataatc
     3361 atctgccccc atctctaagc cgatcacctg atcgctttca gaatctctag ctgtcagcat
     3421 gataatcggc acagtacttg aaactttgcg gatctctctt cctactagca taccgtccag
     3481 tgtgggcaaa ttcaggtcta gtgtaatcat atcccaatgt tgtgggtttt ctaaaaaggc
     3541 atcgagccct tcttttccat catacttgaa agttgcttcc caaccttcat ttaagaaaaa
     3601 catctgcatc atttcagaaa cagattgatt atcttcaatc attaaaatat tcattatcgt
     3661 tccctccagt ttccaggtca tatttctgta atttcttttc tgtcataata aaaataggca
     3721 taattggaaa tactagcaga agcatttcaa tcagaaaata attcgtatgc ccagatgtct
     3781 ttaaataata gccgatcaat gccatcagta agcccataag aaaaaaccag tttccgcttg
     3841 tcttttgagc cagccgccaa tgagcgtctg tttttgcggc aagaggcgaa tgatacccat
     3901 aaaaaggcag atttcctttt gagggcagaa tccgaaaaag actgccaatt attaagaata
     3961 agataccaat actgaaaaaa atcattcttt ccctcctaaa ttctcttctt atagtatact
     4021 ctaaattgtt gactgaacca atatgttcag gaattcttca cgaaaggttt gtcttttgtt
     4081 cattctttgt taagataaac ttattccaat aaaaaaggag ttttatttgt gtcaaattat
     4141 cgtgcaatca ctttctttga tcttgatgga acattactag atgcgaaatc aaaaatcaca
     4201 cccgaagtgg caaaagctat gaacgcatta aaagaaaaca atgttctccc cgtcatcgct
     4261 acaggacgta cagaagcaga aatccactct atcatggaag atgcgggcat tacttctgcg
     4321 gtcaccatga atggttcttt cattcgagta gacggcgaag aaatctattc tcaaacattt
     4381 tcttcagaag aatgtcaaaa aatgtatgat catgtacagt tgaacggtca tgaactttct
     4441 tactataacg atcagaaaat ctggtgtacc ggtcatagcc aaacaatgat caatgcttac
     4501 gacttcattc attcagatgt tccggaaatt gatcctttag gctttaaaga aaacacagta
     4561 aatatgttgc tgatcttatc tcaatcaggt gacgaatact atcacgaaca ttttcctgag
     4621 ctaacttttt atcggaatgg tccttactcg atcgatacag tgaagaaagg aatctcaaaa
     4681 ggggcaggtg tcaaacgtct gcaaaaagaa cttcagctgg aaaaagttcc tacttttgga
     4741 tttggcgatg gtccgaatga ttttgccttg ttggaagctt gcgacaacaa aatcgctatg
     4801 gacaacgcct atgacggatt aaaagaactt tctaccttta tcacaaagaa aaatacagaa
     4861 ggcggaattg tccacgcatt gaagtatttt gatctgattt aagatctttt tttgaagcta
     4921 cctcttttct taagaaaatc gcttattttt tcttaagaaa ggggcagtta ttatataaat
     4981 aatgggatat gattcgcttt tttattgaat ttatcccaat atatgctata ctaattttgt
     5041 atgaaaaata cacgtaaccc ttgttagcta acggggacgt tacggattcg acaggcacag
     5101 tcgagcttga attgcgtttc gtaggttacg tctacgtaaa aacgttacag ttaaatataa
     5161 ctgctaaaaa cgaaaacaac tcttacgctt tagctgccta aaaacagtta gcgtagatcc
     5221 tctcggcatc gcccatgtgc tcgagtaagg gtcctaactt tagtgggata cgtttcaact
     5281 ttccgtctgt aagttgaaaa agagaacatc agactagcga tacagaatgc ctgtcactcg
     5341 gcaagctgta aagtgaatcc ttaaatgagt tgactatgaa cgtagatttt taagtggcga
     5401 tgtgtttgga cgcgggttcg actcccgccg tctccatata tgtatggttg agacagataa
     5461 acatgtatga aaaacgttgt taaatcaacg tttttttatt ttggtcaagg agagaaaagt
     5521 agagaaatac aaaatttttt gcattgattt tgcattcaaa aaaacattca aacatttaga
     5581 aatccccaat acgtattcag gaaaatctat tttaaggttt acaaaaagaa cttttgttcg
     5641 tacactcttt ttgaggtgaa cttttatgct gatggaagga aaaacacaat tatggtttaa
     5701 gcatgttcct tcaaataagt tttttt
//
LOCUS       DADVXM010000107         5671 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.113, whole genome shotgun sequence.
ACCESSION   DADVXM010000107 DADVXM010000000
VERSION     DADVXM010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5671
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.113"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(228..391)
                     /locus_tag="KB927_002453"
                     /pseudo
     CDS             complement(228..391)
                     /locus_tag="KB927_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390190.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
     gene            complement(744..1433)
                     /locus_tag="KB927_002454"
     CDS             complement(744..1433)
                     /locus_tag="KB927_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBB6841335.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            complement(1478..2242)
                     /locus_tag="KB927_002455"
     CDS             complement(1478..2242)
                     /locus_tag="KB927_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBB6841336.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIDRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLQLGKTPVIVHPERNAHFRKDPNHMLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(2270..2968)
                     /locus_tag="KB927_002456"
     CDS             complement(2270..2968)
                     /locus_tag="KB927_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBB6841337.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(2981..3760)
                     /locus_tag="KB927_002457"
     CDS             complement(2981..3760)
                     /locus_tag="KB927_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBB6841338.1"
                     /translation="MEETISLKEIFETLRKHVITILISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQATSTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAPTQPKATNDKTAPSRRSRSRV"
     gene            complement(3776..4720)
                     /locus_tag="KB927_002458"
     CDS             complement(3776..4720)
                     /locus_tag="KB927_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6841339.1"
                     /translation="MAKRRRRSRGKKIFLIILAILVVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGHDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYRDAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(4761..5540)
                     /locus_tag="KB927_002459"
     CDS             complement(4761..5540)
                     /locus_tag="KB927_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841340.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHFNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSLIEQIRNEKIRAAYASKAETVAQQMGYSNTSY"
BASE COUNT         1497 a         1181 c          973 g         2020 t
ORIGIN      
        1 cgtacttttc caaatattat tttccgttat gaacatccaa tatattacaa agtttaaaag
       61 tttagatgaa ctataatctt catttctgca cagtggataa taaattctta tagataaaaa
      121 atagcctctt ctaaagtcac aaatacctta ctcccacatt ttaagtaaac actctgcagc
      181 attctctttg ttataaaatg atagatattc ctcaatttta tctcttatta tgttattatc
      241 agttgatacc attccattaa tgtttcagaa taattacaat attttgggac cggataactc
      301 ccttttgctc gtaaccactc atatccgtta ggattcacta aaagtttacc gtttattttt
      361 cgattctttt tttgaaccgt cccatgaaca taccgattca acaagctaaa ttataaaaat
      421 tggtgtgctg tcattatttt ttggaaaatt tattaatggc tatcaatata cttttgtatc
      481 atactaaata gctcgtcagt tcctatatcg gatataccaa tattaaagca tttagatcat
      541 tatatttaag agtggtatca tcccaaaatt tcgaatattt tcttttatat aagaataatg
      601 atactgaatt gccccattca cctttctttt tttagatttt ctacaagtga ttcaaaccct
      661 ccataattac agttattact tttgaaacga taatatgaac atgtgtaatc ttttttatta
      721 acaatccatc attctatccc taactaatat gctccattgg gcttgacaat aacataaaac
      781 gtttttaaaa tcaacctcaa gtcgtacatt aaacttcgat gactaatata ctctaaatcc
      841 aactcaacca ttttatggaa actaacatta tttctatcac taacttgcca caaacctgaa
      901 caaccaggtt ttacatacaa gcgttgaaga tcatatctcg tgtactcagc tacttccctc
      961 tccaaaggtg gccgtggacc aattagactc atatcgcctt ttaaaacatt ccatagctgt
     1021 ggcaattcat caatgctttt ggcacggata attttaccta ttttagtgac acggggatct
     1081 tctttcatct tgaacattgc accttctatt tcattttgat caagtaattc ttccaatttt
     1141 tcttcagcat ctaaacacat cgaacggaat ttatacattt tgaatgtttt tccattttta
     1201 ccaacacgtg tatggcaaaa aaatatcgga cttcctggct cttcttttct gattcgataa
     1261 gctacataga acatcaaagg agaagctaaa atcaaaccaa taatgcttcc tacaatatca
     1321 atcattcttt taaaaaataa atagatatat cgtttttcaa ctttttcttt atccaaccaa
     1381 acttgattag gatgtacttc actaatacga gataataaat cttcactttc catactttcc
     1441 ctctctcctc atttcctttt tatctacgaa taaagaacta aaataaacca aacttcttct
     1501 tttttacctc ttcatagact ggataactga tttcatcccc gttgatcaga tcctttgcga
     1561 cttgtttcat ctgtactact ttttccttac caaagtcctt agcaatctgc tcatagcact
     1621 cttttaagta aaaggtacgc ttagagaccc catgggcatc agaagcagcc atctgcacaa
     1681 gattatgttt gaccatcatt ttggctgttt tctggatgtc ttttccaaat acaccgacat
     1741 aacttggtgc ggtgagttgg gccaagcatc ccatatctag gaatggcagc atatgattcg
     1801 ggtctttacg aaaatgcgcg ttgcgttctg gatggacgat cactggtgtc tttcctagtt
     1861 gtaacaactc aaaaaagagc tgttctgcat ataacggcac ttccagtgtc ggaaattcga
     1921 ttagaagata tgtatcatct aaatctgtaa ataaaatttc atctcggtcg atgtcttcga
     1981 tcagtgttcc ggtaatacgt acttcttgtc cttccaataa cgtcaaaggc aattgtcttt
     2041 tctctaattc tgcttgtaac gaagcgacta gagaaatgac ttgtgatttt tcattgctgt
     2101 attttccatt attatgatgg ggtgtgcata aaatatgtgt gatcccttgt tgaatcgctt
     2161 tttcagccat ggcgatactg gcatctatgt tttctgctcc gtcatcgatt cctggcagga
     2221 tatggcaatg tagatcgatc atttctcttg tctcctctct ttttatttct taattcccgt
     2281 agtaatagcc agcatctttg ctgtgttctg ccccattgta tacaacacca aggactcgcg
     2341 cttgtaccat atccagcaat tcttttgctt tagtcaatga ttctttccgt gacatatttt
     2401 cacgtacgac caataaggtg ccatccgttt tggaagacat gatctgtgca tctgttacgg
     2461 caactactgg cggcatgtcg aagatcacta catcaaatag ttgtcttgct tctgctaaaa
     2521 tctgatccat tcttggcgaa cttagtagtt ctgatggatt tggtggttta ggtccacttg
     2581 gcagaatcga caaattctcg actggtgttc gttggatctc atctgctaca cttcctgatg
     2641 aactaagaac ggtacttaat ccgcttgcgt tgttcaactt gaacgtttta tagatgacgg
     2701 gcttacgtaa gtctgcatcg actagcagca cccgttgacc agatttggca aaaacaacgg
     2761 caatgtttgc tgcagtggtc gatttccctt ctccaggtcc tgatgaagtc acaacaatcg
     2821 ttttaatttg ctgaccagct gcggaggcaa actggatatt cgtccgaatc gtacgatatt
     2881 gttcagcgat tggtgaagag gggtttgtga gtgtgaccaa actgactgca tgagtttggg
     2941 ctgctttttg tttctgtgtt cgtgccattt ttctttcctc ctagactctt gagcggcttc
     3001 tgcgtgatgg cgctgtttta tcgtttgtag cttttggttg tgtcggagct ggtccttttt
     3061 tacggatacc agcattcaat tctttcgctg acatttctgg tacagtccct aagatcggga
     3121 agcccaatgt atccgtcaca tatttttcat cttttactgt ccggtcgagt aattcaaata
     3181 agaaagctag acctacgcct accatcattc ctaacactaa gccaatcact agattcaatt
     3241 tattatttgg cgaaacaggt gtcgtattgg caactgcacc tgagatgatc gagattttat
     3301 cgacattcat cacgtctttg gcgttctctt ggaatacttg tgacgttgta ttagcgattt
     3361 gttgagccgt cactgcattt gtgcttgttg cttggatcga gaacatttgt gaattttgtg
     3421 actgattgac ggagatggca tctttgattt gtccagcagt catttttaca ttgtcttctg
     3481 tttctaaacg atctttgact tcatttagta ctagatcact gacgatcata tccttatacg
     3541 tattgatcat ttgcaggttc gtattgacat cattgacatt tgcagtatct gattgcggca
     3601 gtgtcacgat caattgggct tgtgagctgt attttggcgt caagatgaaa aacgtcacga
     3661 tgcctgagat ggccaagcca gcaaacattg agatgaggat tgttatcacg tgtttgcgta
     3721 atgtttcaaa aatttctttc aagctgattg tctcttccat tttttctcca ctttcctatt
     3781 tattctctag attcatttga tcttttaatt cttttttcac acgatcaagt tcttgatcgc
     3841 tgactttttg gtatgagata ttgtcttgca tgaagccttc tccttgcagc tgatcttgct
     3901 tgatcgtacc aaatgcatcc cgataatcta aagcaatctt tttcatttca tcaaagctca
     3961 tgtctgtttt catattcgac tctagagcat tcaaaacgga ttgatagttg cttacaccgt
     4021 tcagactcaa cacttttttc gctacacctt ctacgatctt tctttgacgt tcttgtctgc
     4081 cgtagtcacc atttggatct tcataacgca tacgagaata agacaatgcc tgatccccgt
     4141 tcaatgtgat tttaccgatc gtaaaatcat agccatcttg tgagaaggtg aggtcattat
     4201 tgacttcgat accaccaact gcatcaacga gttcttttag acctttcata ttgattgaaa
     4261 catagtgatc gattgggatg tctacatatt tttgtacggt atccatcgcc atggcagctc
     4321 cgccgaatgc gtaagcgtgg ttgatcttgt cttttgtgtc atgtccaacg atgtcgacat
     4381 acgtatcacg aggaatgctg acaatcgttg tctgtttgtc ttcaggactg actgtggcaa
     4441 ccatcatcgt atctgatctt ccttgatcga cccgacctaa atctcccgta tcaatcccca
     4501 tcaatagaac agagaaagat tcttgtttgt ccagatcaac tggttttgtt cgttctcctt
     4561 gggttcgttc cactgattcg taagtttttt caatagaatg tgagagatct agatataatt
     4621 ttgctcctac tcctacgatt gctaatacta atacgacaag aattgctaaa ataattagaa
     4681 atatcttttt ccctcttgat cttcttcttc gttttgccat agtttcctcc gtttgctagc
     4741 cttgcttgaa ttctcgctta ttaatagctc gtattgctat agcccatttg ctgagcgact
     4801 gtttctgctt ttgacgcgta tgcggctctt attttttcat tccggatctg ttcgatgaga
     4861 ctgagtgcgg tcaaatattg atcgtaagta gcagtagctg ttacttgacc gtctttcagc
     4921 atcgtatcga atagctgatc tagttgcgtg acttgcgcga tctgagtatc agcgaatcct
     4981 agatattgca taacaaccgt tttccaagga ctatctttaa aaaagctcat attttcacgt
     5041 acacgagcga catctgcact tgtcaccttt tctttgatga cgacatcgtc tacagcttgc
     5101 tgccagtttg atacattttt agtaaataaa tcgttgacag ctgtctggat cttcagtttt
     5161 gattctgcat cctctaactg cgttaagact gctttctttt cttcttggat cgcagcagct
     5221 tctttaggta attctgattc cttgatgtca taatcatctg ccgaaagttt gatagaagat
     5281 agtttatgtg acaaatttga aactgtttct tctgttattt caggatttag gaaaattttt
     5341 tcttttgtac tgtacagctt atctacttct tttgataaag aggtcacggt gtctttttga
     5401 ttggtgatgg cagattctgc gtaattgatc cgttgatgat gttgccgctg attattgaaa
     5461 tggtatccaa acaagcaaat cacaatagcg cctgtgccta ccgccacagt agccaataac
     5521 ttgacgaacg gcttttccat agattcactc ctaaatattg atgatagata aataaagatg
     5581 tgattcattc ccatcagaat gagcgctttt tattttaaaa gcataattaa actaatatat
     5641 tcatagaaat atttataaac aggttttccc t
//
LOCUS       DADVXM010000108         5134 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.114, whole genome shotgun sequence.
ACCESSION   DADVXM010000108 DADVXM010000000
VERSION     DADVXM010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5134
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.114"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(494..1246)
                     /gene="xth"
                     /locus_tag="KB927_002460"
     CDS             complement(494..1246)
                     /gene="xth"
                     /locus_tag="KB927_002460"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBB6841341.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            1359..2303
                     /locus_tag="KB927_002461"
     CDS             1359..2303
                     /locus_tag="KB927_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6841342.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQLCTRLARLY"
     gene            2352..3287
                     /gene="murB"
                     /locus_tag="KB927_002462"
     CDS             2352..3287
                     /gene="murB"
                     /locus_tag="KB927_002462"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBB6841343.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAAFAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            3585..5063
                     /locus_tag="KB927_002463"
     CDS             3585..5063
                     /locus_tag="KB927_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841344.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT         1789 a          833 c          984 g         1528 t
ORIGIN      
        1 tctcaataaa cggtgttcaa aagcttgcat ctgcggtaat aagtccaacc aaacgaaaaa
       61 tatgaggaac tatttttgtt tggctgttct tattacttga tgcagtgcag ctttttcaca
      121 acctcttaat aaacggtgtt caaaagcttg catctgcggt aataagccca accaaacgaa
      181 aaatatgagg aactattttt gtttggctgt tcttattact tgatgcagtg cagctttttc
      241 acaacctctt aataaacggt gttcaaaagc ttgtatctgc ggtaataagc ccaaccaaac
      301 gaaaaatatg aggaactatt tttgtttggc tgttcttatt acttgatgca ggacagcttt
      361 ttcacaatct ctcgataaac agtgttcaaa agccagtttc tcggtattat gccaaattta
      421 tgcaaaatgt ggaaagccat tttcacaaaa tttttcttaa tactcgaaac taaacgactt
      481 tttcacaacc tctttatttc aaatctaatt ctactggaca atgatcactg cccataatgt
      541 ccgtatggat ctttgcatca gctagtcctg gctctaaatc tttgctcgtc aaaaagtaat
      601 cgatccgcca accagcattg tttttccttg aattgaatcg gtagttccac caagagtaga
      661 caccttcctg ggttggataa aaataacgga atgtatcgat aaacccgtta tccaacagtc
      721 gagaaagagc cgctctttct tctggagtga atccagcatt tttttgattc gttttccagt
      781 ttttcaaatc aatcttttga tgagcgacat ttagatcccc acacacgatg actggttttt
      841 gtttttttag attttccaaa taattataaa aggcttcttc ccattctaat cggtaatcta
      901 aacgttttaa ttcgctttga gaatttggcg tgtaacaggt tacaagaaag aaatcggaat
      961 attccaaagt aatcagacgg ccttctgtat catggatatc gatacccatt ccgtaagtgg
     1021 cattcaatgc tggtttttta gcaaaaatcg ctgtgccgga atagcctttt cgttccgcgt
     1081 aattccaata ttgataataa cctggaagat ctaaatcaat ttgtcctgct tggagtttcg
     1141 tttcctgcag acagaaaaaa tcggcgtcta actcatgaaa aacttctaaa aaatttttat
     1201 ttacgatggc acgaagcccg tttacgttcc aagagataaa tttcaataaa agcacactcc
     1261 ttcgaattaa tttccttacc tttgcgatac tattgtacct cattttagta aaaaatggtg
     1321 taagatgaaa gtaactaaat gatccaggag gaaagtagat gaagattggt gtaatcggtg
     1381 tagggaatat cgcagaaaaa gcatatttac caacttatgc gaaaaaacaa ggaacacttg
     1441 atttttattt tgcaacaaga aataaagaaa caaaagaaag aattcaaaaa gagtacgggt
     1501 tccaacatct atatgaaacg atcgatgagc ttttagaaga aaaaatcgaa gcatgtatga
     1561 tccacgcagc aacaaaagta cattatgaat tagccaaaaa atgtctagaa aatggtatcc
     1621 atgtttatat tgacaaacca ctgagtgtcc atctaaatga agttcgtgaa ttgcaagaat
     1681 tagctgataa gaaccaaata attttgatga tcggtttcaa ccggcgcttt gctcctatgg
     1741 tagaagaatt gaaacgtatc ccagataagc ggttgatcca cctgcaaaaa aatcgaatag
     1801 cggcaaaaga aacgacagag ttcgtccttt atgatttgtt tttacatctt attgatacag
     1861 ctgtgtattt attagatgaa cccattttga gaacaaaata ccagataaga gaaacaaagg
     1921 aatttttgga atatgccatt ttacaattag aaacacaaaa tcaaacggct attttaacga
     1981 tggatttagc aagtggcgct aatatagaaa aatatcaagt aacaagtaaa aatggtactt
     2041 atgaagtaaa cgatctgacc cagcttgtca tccaagatgc tgatggaaaa aaagtgaaag
     2101 aatttggcga ctggacaaac acgctagtca aacgcgggtt tgagccaatg gtagaggcct
     2161 tcttttctca gatccgttta ggtaaatcgg aaacagaatt gcttaaacaa aaagaagttg
     2221 taagaagtca tgaattatgt gaggaagtgc ttaaagatca ctaccgtcat caactttgta
     2281 caagactggc aagattgtat taagcgtgat agaataatga ggacgtttga gaaaagaaag
     2341 gaaaatcctc agtgaataaa gaagaaatag ttgaaagctt agccacgatt actatattgt
     2401 ttgatgaacc attgatgaac tatacgttta cgaaaacagg tggaccagct gatgtccttg
     2461 cattcccgaa aaaacaagaa gaagtaaagc aaatcatcga ttattgccga atccatgata
     2521 taccttggat ggtattagga aatgcaagca atctgatcgt tcaagatggc gggattcgcg
     2581 gtgtagtcat catgctgact gaaatgaaac agattcatgt caaaggaacg atggtcattg
     2641 cggaagcagg tgcctcactg attgatacga cttatgcagc ttttgcagaa tcattgactg
     2701 gatttgaatt tgcttgcggc atcccgggaa gtgtcggtgg agcggtttat atgaatgcag
     2761 gtgcgtatgg cggagagatc aaagatgttt ttgctgaagt ggatcttttg cttgaagatg
     2821 gaacattgaa aactttgaca aaagacgaaa tggtattttc ttatcgtcac agtaaagtcc
     2881 aagaattacg tgctatcgta ttggaagctc gattcagttt gcaaacaggg gattatgaag
     2941 caatcaaagc aagaatggat gagttgaccg aattgcgtca atcaaaacag ccattagaat
     3001 acccttcatg cggaagtgtc tttaagcgcc cagtaggaca ctatacaggt cagctgatcc
     3061 aacaagcagg attgcaaggc ctgaaatggg gcggtgcaca agtctctgaa aaacatgctg
     3121 gattcatcgt caatatcgat catgcgacag cgacagatta tattgaattg attgcgcaca
     3181 tccaagaagt aatcaaagaa aaatttgatg tgtctttaga aacagaagtg cggatcattg
     3241 gagaaaaaca agcaatatca gaaacaagca gaagtttagc caattaataa gtaatggaac
     3301 ttaaaataag taaaagagca ggacggtggc cgtcctgctc ttttttgtgg ttgtttacgc
     3361 aaatgacgca aatcttgtac attttaacac aataaaacaa aaaatataga atatttcctc
     3421 ataaattttt ccattttttg caatattctc aaaaaaaaga taaaaaatga gaataactga
     3481 tgaaaaaaca agcataatcc atcataaaat cagtataggt gaaaagatga actttcatct
     3541 gcatatcaag taattggtat gaggcatttt ttgaggtgta ggatatgaag ttggattacc
     3601 ttatagaaga ggaagataga gaaaaactgc tgctagctag atatttagaa tttgagaaaa
     3661 agaattatgt agtgctgcct aagttatatg aaacattagg tttgtctaaa tttaaaacaa
     3721 gaaattatat catagaatta aataaagaat ttactgaatt caaaacaaag ccagagatcc
     3781 aaatttcaga agaagcagag atccatgtcg aacgtctgaa tttgacggat atcaaaaatt
     3841 taagaagaat ctactttcaa cgatcaaaaa ttgctcgact gttaacggag atcgtggatt
     3901 caaaagtaac gatcgaaaaa tttgcagaga atcatttttt aagcatatca agagcctatg
     3961 taaaaagaag agaattagtc tcttttcttg aacagcatca aataaagtta aagaaaaaca
     4021 tattagttgg ggaagaaata aacatacgga acgtattatt tggggtatat ttcggggtct
     4081 ttaatggttt ttctatgcca tttagagaaa gcgtcatgaa tgaagcaaag agtatcgtgc
     4141 aatattttga atatctgttc aatttaaaac tgtctgcaac aaaacgaatc aaattcaatt
     4201 tgctaaccac tattagtttg ttgagggcct atgggaatca accaatcgga aaacgtttct
     4261 tttcagatga atactttaag agctcagaag gaatgaagat catcaaggat ttatcacata
     4321 tttcttttct tcatatccct aaagagcaga tcattgatga gatttcttat atcatgttgt
     4381 ttttgatcac ggaagaagaa tttgaattag atggcgcatt tggacttgcg gaagctcatt
     4441 ttcatgatat ccacatgatt agtcaaaaaa tgtcagtgga attgattgat caattaccat
     4501 tttcgattga aatctctgaa gaagaaagac tatatatacg aaaagaactt cgtatgggta
     4561 tgatgcatgt caatcgaaaa aattggatat tcgactttga gatgactagc tttacgtcta
     4621 aaaagcagct acagtttttc ttcgagacgt atccaatatt cagtacagca atccaaaagg
     4681 tcatacaaga gaataaacgc tatttcttgg gaaaagatga acgtttcatg attcgcttat
     4741 tttatgatta tctcttttta ttggtcggta tttgtccggt atcatatttt gaagcaccga
     4801 ttcatgtctg tattgatttt tcgcaaggat ctgcttatac cgattacatt atttctcaag
     4861 tgaaaggatt taaaaattac aatattgtga ttgagagtcg aatcacttct cgtacgaata
     4921 tttatttatc tgattgttta cttgaaaaat ttaataaaga acagataatt tggaaaaatc
     4981 caccgactcc agatgactgg gaatattttg gaaataccat catcagagaa aaaaatagac
     5041 atttaactga aaaaatcagc tagtatttat ggatggcagc tttgtctcac atatttatta
     5101 gctgatttat gtttttttca aagaaaaggt aact
//
LOCUS       DADVXM010000109         5113 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.115, whole genome shotgun sequence.
ACCESSION   DADVXM010000109 DADVXM010000000
VERSION     DADVXM010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5113
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.115"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     misc_binding    complement(32..259)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(621..1823)
                     /locus_tag="KB927_002464"
     CDS             complement(621..1823)
                     /locus_tag="KB927_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6841345.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(1883..2086)
                     /locus_tag="KB927_002465"
     CDS             complement(1883..2086)
                     /locus_tag="KB927_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBB6841346.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(2228..3460)
                     /locus_tag="KB927_002466"
                     /pseudo
     CDS             complement(2228..3460)
                     /locus_tag="KB927_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            3623..4435
                     /locus_tag="KB927_002467"
     CDS             3623..4435
                     /locus_tag="KB927_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841347.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1558 a         1058 c          798 g         1699 t
ORIGIN      
        1 aaaaaaaaat ccttttacta gcaaatacta gtaaaaggac gattatactc gtggtaccac
       61 cttttttcag aaaaaacatt ctttctctca gcctgacaat aaaatcagtg gtcttggtaa
      121 cgaaagactg ttcgtttttg cctacctttc gacaaaaaat cctctaaggc cattttcgac
      181 agtcaacttc tagcttttta caccaaccaa agcctctctt gaaccatttt ctgtctactt
      241 tccttctcat cggatactat tagaataaaa ttagaatagc atgtttgaaa gaaaagtcaa
      301 tagggaataa gaacaaacaa aaactaattt gttattctta gtaatttgtt tgtggaatac
      361 aataaagctt ttctaatatg ataattgttc agtcgtcctt tcatcttaga tcacttcctt
      421 aaaatgatca tacccgtttc aaccacataa aaaaggactt aattttgaaa aatttcccat
      481 caaaactaag tcctttttat tatagttatg caaatttgct tattttctcg ctatttccga
      541 tacatcttga acaggtgcaa ttcgactgaa aacactggtg caaaagcatt tatttgtctt
      601 atggtagaac cgtggaaaac tcagactggt aataaattgt cattttttga aagaatagcg
      661 ccctcttgaa cattatcaat cgcacttacc acttgttgat ctgactttgc atataagtga
      721 ccgtaagttc ctaaagtgat ttgaatattc gcatggccca atcgttcttg aatagatagc
      781 ggttgaatat tctgctcaat tagaaatgca acatgagaat gtcgtagcgc gtgaagctta
      841 atcggtttga cacccgcttt tttagcagct tcttttaacc agttcgcaaa agaataaggt
      901 ggcgtaaatg ttccgtccaa ctgagcaaca tattcaaaat ttccaatacg tttttgcaag
      961 tcataccact gtctgagttt taaggaaagc ttcttcccca acccaatcgt tcgataagca
     1021 catttagttt tgggagtcga aaagtaccaa tcatcttttg tattataaat caatgtcttc
     1081 tcaatcgtta tcgtgttttt ctcaaaatct acattcgacc aagacaaagc ttcaagttct
     1141 ccaatccgaa tgccagtata aaagagcatt tcatacacaa tcttccgatg gtgggtttga
     1201 atcttatcat ccttcaattc attcatcact ttttgaaact cactgtgttc ccaaaactca
     1261 actttcttat tctcagaagg aagcgaagaa acatcttcaa cgggattttt agcaatcacc
     1321 ccctctttaa cagcccgatc caatacaatt tttaggtgcc ctcgaatccg attgatataa
     1381 gattttgata acgtttcgcc attaactttt ttccgcgaat tacgtgactc tgtctggctt
     1441 agttcaaata accaatcctc aatatcgtga cttgtaatat ctcgaacacg aaaatgatag
     1501 aaaaactgca tacgcttttc gaaaatgaat tgcgcattct catatgtttg acttttgacc
     1561 tgtctctcgt accattttac aaacctatcc ttgtaaaact cttcgaaagt catttgattg
     1621 gtagaacaca gttgattagg aattgtcttg ttaaaatcat gtgtttccat gtacttgtca
     1681 taagcaattt tggcatcttt ttgtgaagca taacctcgtt tagtcttctg aacctttctt
     1741 ccattttcat ctatacctag atacgctcgg aagaaccatt tttttgtctt tttatcttgg
     1801 taaatatttt taatttttgg catcgttcca ttcctccctg tacttgagaa aagctacttt
     1861 aatagtaccg cgcttgtact gtttattccg caacttgaat gtgaaaaaga tgttcaatta
     1921 ctcgggatgg caccacacca acttggcgat tattataaaa atcaatacct tcaatccttg
     1981 caagatatgc cttgctctct ttaatcattc gtgcagcttg actaggttta aagcccatct
     2041 ctatcaaaat tgcacgattt accatgaaat cacattttgt ttccattctc tcacctcctg
     2101 attctttact ccttttaaaa taatcctctt tataatctat tgtttctcat tcgatggttg
     2161 tgttatactc gtcttgtcga ggcggagtac gttgcacaac ttgttgtgta agcagtactt
     2221 tgctttttta gtagcttgtt ttctcatttg atatactttg taattttcgt tcataatact
     2281 caacctcctc ctgataatac tccgggtctg ccttcatatt ttggagaagt ttgatctgtc
     2341 ttggattcat ttctccttgt tcaataatca aaggcaacaa ggaagaatga aacgtttgat
     2401 cgacctgtgc aataaaaact aatgatggtg aaacaccatg aattaaccaa ctcatagttt
     2461 tctcaaaact ttgaggaatt gtatctaaag aaatggtgat tgcgccataa ttgctaataa
     2521 aggctgccca tttggcatca acttttgcac ctagatcatt tggatcacgg tcataaaaac
     2581 aaattgctcc attaagtaac tcaaagaaca gtttggttaa atcatgggtt tttgaaataa
     2641 tctttgccaa gctttgcgct ttctcttttc gataccgtag ttcaaagcga ttctttactt
     2701 ttgcctcttc taaaggaatt cctcgtcgct tccgttgttc atggtccttc tgataaaagc
     2761 aaaaacgaca ctgactcttc tttgagccta aatacaaggt ctcaccattt gattcattgt
     2821 ttatgatatc cgtaccgcca tgagattcac tcacttgaaa agtggtccac acatggccta
     2881 gtattacctt atgcttaagt tctggaatgc tgagactccc cacaaaatca tctaaagtaa
     2941 aatcaatccg tgtaaagttc ccctgataat ctaatacctt acgaaaaaac tgttgccaat
     3001 ttgtttttcg tgtttttagc catcttgcta agtgtttaca gccttgacct gaaaactcca
     3061 tcacagttcc tttaaccgca tcgtcaatgg aataccgaat cgtgattact tgattccaca
     3121 cgtattggcc aatatagccc tttggcgcat aatccagttc ctcaaaacgt tcaatgggca
     3181 tttcaataat ctcttcaatt agctttaaat gttgattcga gaaaaagtga atggttagat
     3241 aatcaatcaa aacacggtta actggaacga cctcttcttg caaactatcc aacacaagat
     3301 tcaatttttc ttcacttaat tgtctcgttc ctttttctac tttcgataat aactatctcg
     3361 aaatccccac tttttctgct aaatatcgtt gtgtccaccc cctttcttct cgagaaactc
     3421 gaatggcttc accgagatca tgttgattaa cttggttcat agacaaacct ccttctgcta
     3481 tttacttgtc aaagaaccta ttgaacttat tttaagtaca tttttattgt acgcctgtat
     3541 ttattttaag tcaatatgtt ttgacttttt ttaagtacac acgtatacta aatttaagaa
     3601 cttatcctga ggaggagttt tcatggagat agacaagcaa gcagtcggca atcgaattcg
     3661 gcagattcgc caagaattaa agttgagtat ggagaaattt ggcaaactaa ttggtgattt
     3721 accgcgaagt acagtcaata actgggaacg tgggatcaac cttccaaaaa ccgaaaccct
     3781 tcaccaaatc gcagagatag gtcatgtcac caatgaatat cttttgtatg gtgatcaaga
     3841 gaatcaatac attttagaaa tgctccaaaa aaaggcaggt aagcttgatc ctaagattga
     3901 aggtctcata gtagacgaaa tcaaacacgc tgaccttgtt agtgaaaaag aaatggatcg
     3961 aatgattgaa ttttttatta caaatctcat tccaccaact gaacaagacc agtttacttt
     4021 ccaatgtatc gatgaaaaaa agcagcttta tcttggttca actaattttg gtaaggaagc
     4081 ccagctctat ttgcaacatg ataatcaaaa tcatattctg cacatgatgc cctttacctt
     4141 ctccaacttt agtgtggatc gcatactcgt ctatttagca aatcaaaaat cctattccta
     4201 ttttgggaaa catttaccca aggaactagg tgagaaagcc atccttctat actcaattaa
     4261 tcaattgacc agcgatgtgc gaattgcccc gttggtctat tcagaagaaa ccgcttctta
     4321 tcagtacaca gaggacaatc aatatctact agaacagcaa tatctttatc taccattcgt
     4381 gatggaagtc gagaaagaac gcctgttaaa tgcagcgtat ccatcatcaa aatgaggtga
     4441 caaaattgat aagcacgtga caaagaaaat actgctagga cactccccaa tgggtagttg
     4501 tcacagtttc ctgttctttg ttagccccct gttagaaccg ggggctttat tcctgcagtc
     4561 cggctacgcc ttcctgcaat agacaaaact ccagatcggg taattcgctt gtggcgaaac
     4621 ccgacctgga gtttgtctct gtattttgaa ccctaaaaat taatcaaaca gactgatatt
     4681 ctcataatca gcgcgaaata agccattaag tacagttttc ctacctattt ttgataaccc
     4741 gctggttagt taatattcct tttccgagag agataaatga ttggttaaat ctatatacat
     4801 ctcaaccttt aaaaatgttt tcgaaatact tcatcagtac atgtcataca aattaccagt
     4861 gcattctcaa attctagttc tttaattgat ttcagttgag gagcagttac ttttggcgga
     4921 aatttccatt tttgtccaaa cctcttcccc cgatgaaatt tctttgttgc aattattgca
     4981 atgaaaaatt tttgtttcaa aaatatacat aattacttcc tccaataaaa actatctacc
     5041 tctcaaatta tttttctcta ataagaaaaa cagaaaaggt aataagatac aacagtgatg
     5101 attcctaata aag
//
LOCUS       DADVXM010000110         5038 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.116, whole genome shotgun sequence.
ACCESSION   DADVXM010000110 DADVXM010000000
VERSION     DADVXM010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5038
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.116"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="KB927_002468"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="KB927_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBB6841348.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="KB927_002469"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="KB927_002469"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBB6841349.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="KB927_002470"
     CDS             complement(2169..2906)
                     /locus_tag="KB927_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBB6841350.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="KB927_002471"
     CDS             complement(2997..3524)
                     /locus_tag="KB927_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841351.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="KB927_002472"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="KB927_002472"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBB6841352.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="KB927_002473"
     CDS             complement(4401..4886)
                     /locus_tag="KB927_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBB6841353.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
BASE COUNT         1337 a         1125 c          863 g         1713 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttt
//
LOCUS       DADVXM010000111         5024 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.117, whole genome shotgun sequence.
ACCESSION   DADVXM010000111 DADVXM010000000
VERSION     DADVXM010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.117"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            467..730
                     /locus_tag="KB927_002474"
     CDS             467..730
                     /locus_tag="KB927_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6841354.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            730..996
                     /locus_tag="KB927_002475"
     CDS             730..996
                     /locus_tag="KB927_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6841355.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            1197..1685
                     /locus_tag="KB927_002476"
     CDS             1197..1685
                     /locus_tag="KB927_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBB6841356.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(2226..2897)
                     /locus_tag="KB927_002477"
     CDS             complement(2226..2897)
                     /locus_tag="KB927_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6841357.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(2894..3811)
                     /locus_tag="KB927_002478"
     CDS             complement(2894..3811)
                     /locus_tag="KB927_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6841358.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            complement(3808..4449)
                     /locus_tag="KB927_002479"
     CDS             complement(3808..4449)
                     /locus_tag="KB927_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6841359.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            complement(4453..>5024)
                     /locus_tag="KB927_002480"
     CDS             complement(4453..>5024)
                     /locus_tag="KB927_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6841360.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
BASE COUNT         1565 a          975 c         1081 g         1403 t
ORIGIN      
        1 gtgattcaca aacccaacgg tctaagcaag tatcaaatcg atagtgaaca tgaatgacag
       61 gagacgaaag aggcaatcat ttttgaggca gtagaagact tgacggccaa aatcagtttt
      121 gaataaccgt tacaaatctt tcgtgcgtat cctcaggtta ttcaagatat caatcaagtc
      181 acactgcaac gaggaacctt cgtgtattgg tgttgttgca tagactcaca ggctttggat
      241 tcgacctttg ctaaagatga tacgttgtta ccaattactt tacgtttggc taccgctagt
      301 cgtaaaggag taagaagtga gcgtggacaa agatcctccc taaaaagggg tctttttctc
      361 tatgtaaaaa agaggaaaag tttgctgaat ttaagtgctt tattgtattt ttttgacgta
      421 cttaatcaag tacgctataa ttatatcaga aaaaggagga gagacaatgg ctaatacaac
      481 gatgaatcct agcactgctc gtaaaaattt ttatcagtta ttgaaagagg taaatgaaaa
      541 tcatactgaa atcgagatta ttagtgatcg tagtggaaac aatgctgtat tgattgggct
      601 ggaagactgg agagcgattc aagaaaccct ttttcttgag caaacaggta ctttagataa
      661 agtacgagac cgcgaaaaag acgacagtag ctttacgaat atcgatgata ttgattggga
      721 agctctttga tgagtaacta tacagtcgca atcaaaaact ctgcgaaagt ggatttaaga
      781 aaaatcaagc aaacgaattt aaagaaacaa tttgaagaag tgattcagac attgaaggaa
      841 gatccatata tgcccacgca gtcttttgaa aagctgagac ctacacatga aggcagatac
      901 tcacgcaggc tgaatagaca gcatcgagtg gtttacaaag ttgatgagga aaataaagtt
      961 gtagaaattt attctgcctg gacacattat gagtgaagtg agaagagcca acctttttag
     1021 atagttaaca aagagtctcc ccaaaaagga gactcttttt ttgttctaaa accaaccttc
     1081 ttggatttat tgcatgattt ctttaatttg ttcctatatc tccacctttg aagggtcatt
     1141 gtttgagttt aggaatggaa tgttgacggg tttatgtaaa acaaggagga agaagtgtga
     1201 caaggaaaat cagtaaaatt ggagcatcgt tgttagtgtt ggcagtggca acgaccatcg
     1261 attatcgcca aagtgaggcg aagacaattg gaaatgtcgt ttatcgagaa acagccaaaa
     1321 gtatgttgaa aaaagcaatg gacaatcaac cggagtcgtc ttattggttc ccagaggatt
     1381 cgttggcatg gtcttttgga aaagatacag atacgaaata caataccagt gtcgttcctt
     1441 tagcagagcg ggtatccaaa gcgacattgc cgaacatgaa tgtcactcaa acggaagaag
     1501 ttaaagtcgt ggcgctttcg gccatgaata gcagtatcaa cggcaatgca tcacgaggga
     1561 tcgatatctt ttacgccaat gtcttttctt attggcaata tatcgatcaa ttggtttacg
     1621 ggggtgctct tctggtgaag gatcatcgta tcgccaagtc tagttgcgac ggatgcagtc
     1681 cataagaatc gtgtaccggt tttaggaacc gcaaacctcc catggcgaga agctggaatg
     1741 gctagatatg tttttagcca aggatgagga tggcaagttc ccgattgtat aaaagatgat
     1801 cgaagttacc gatacggcag tcaccagttt tgatgatgca gctgaaggca tcgaacaatc
     1861 gaggactgat ggaaaaggct taaatgaaag ccacgccaaa ggatgtaaga attgatgccc
     1921 aattcaaaga acaagcagac gagtatttag agatcatgtg gtatgaattc catgacgagt
     1981 gatgggaaaa tggattggca aaatgcctta gcggataaga aaaaaactta gtcggtggat
     2041 gcagatatga acccgttggc agtatgaagt tggagtatac ggaatggata aatagctaag
     2101 aaaagcaact ctttgcccat aaggagggaa gaatcagagt ggattattgc cttaaaaatg
     2161 acagaactaa aaaagccttt gcgaccaaca aatggtcgca gaagcttttg ttttttacaa
     2221 taacatcagc gtgatgtacg gctggctgga tctagccgtc tttccaaaat acctaaaagc
     2281 cagtccgtga tgatcgccat taatgcagtt ggcaatgcac ctgctaaaat aatcgatgtg
     2341 ccctctgttg cattggttcc tcggataatg atatctccaa gaccaccagc accgacgaat
     2401 gcaccgatcg cggttatccc gatggcaaca actaacgcgt ttcttatgcc tgccatgata
     2461 acagaaacag agagtggtaa ctctaccatg aatagtcgtt gtctagcagt catccccatg
     2521 cctttgccga catcaaggat gtttttgtct acttggatca tcccggtata cgtattcttg
     2581 atgatcggta agagggaata caaaaataca gtaacaatca cgacattgac tcccaggcct
     2641 aatccaatga ttaaaatgga gatcatggct agagaaggga tcgtctggat gatattcgcc
     2701 aaacgaatca cccagtttgc taatttacgt ctcctagaaa tcatgatccc aaccggaatc
     2761 ccgacaactg ctgcaaagag gacaccatag atagaaatca ggaagtgacg gataaattgt
     2821 gcaaagatat aggagccatt ttcctggaaa taatagaaaa attgttgaaa gacattcatt
     2881 ttatccaatt gcttcacttc ccttcaaaat agtggttttc ttgtaagaaa cgttgtgcta
     2941 ctactgatgg ttccactaga ttattatctg cttcgtagtt caattcctgc attttttccg
     3001 tactgatggt atgacctaac ttatttaagg cttcttttaa atgaggcgta tcagctaata
     3061 tcttgttgtc tacaactgga gcagcatcat atggtgggaa gaattgacga tcatcttcca
     3121 acatgactag atcataactg gcgatccgtc catccgtaga gtagccaaga acaatatcca
     3181 tttttcctgc ttcgactgcg tcataaacaa gtccaatctg cataggtaat atcgaattga
     3241 aggagaagcc ataagtttct tggaagccgt cataaccgtc tcctttacga ttgatccaag
     3301 aagtatctac accagctact aattcatccg ctacattttt cagatcgctg actttagata
     3361 gatggtattt ttgtgcggtg tcttttcgaa caagaaagac atacgtattt tcaaaaccat
     3421 aggacgggaa ccacgtttga ccgtatcttt tctcaaattc atctttcacg gtagcaaacg
     3481 cttttttcgg atctttttca ggaggaaggt tcaatgtagt cgttaaatct gttcctgtgt
     3541 agcgagccgc tgaaattgaa gcatctccgt tcatcatcgc ttgatggttg atagttgtag
     3601 tagccagatt gttgatgatt gcggtatttt tatctgtata atgttcaacc attccggcaa
     3661 ctagacttgc taagatctgt gcttctgaag tgattccacc tgtgatcgaa atggtgtctt
     3721 catctgtatt gctggcaaga ccagggaagg aacaactcgc aagtataaga agagagaaaa
     3781 gaaccatggt catttttagt atacgtttca ttcttcattc tcctctctaa gtgcgatcgg
     3841 tgtcagccgg tgttccaaga gacctagaag ccaatcagcc aatagtgcta aaattgttac
     3901 agggatcgta cctgccaaaa tgagatctgg ttggtaatta ttcagtccac taaaaatcaa
     3961 atcgcctaaa ccaccagcgc cgatataaga ggcaagtgta gcccatgcaa tcacgtaaac
     4021 ggcagctaaa cgaataccag ccatgatcgt tggcatagca atgggcaatt caacggaaaa
     4081 aatggattgg aactcagtca tccccatgcc ttttgccaca tcccgataat tccaatcgac
     4141 atttttcatc ccaatgtacg tattacgtaa aatcggcaat aatgaataaa taaagagtgc
     4201 gataatcgca ggtaatttac ctacgccaaa tagcgggatc atcaatgcca ataaagcaag
     4261 agaagggatt gtctgcaagg cactggttaa gccaatcaca atcgtggcag cttttggaaa
     4321 acgtgtcagt aagacaccaa gcggtacagc aatgatgata ccaatgatca aagcaagtcc
     4381 tgaaatataa agatgttcaa aaccttttga gagaatttct gaaccgtgct gatgaaaaaa
     4441 ctgctgcata ggtcagacct ccttagattc ttcaggagta gctgactctg caacatcagt
     4501 agttgcggga tcttctcccc aaatcacatc gtagacgata tccactaatg atgcacgagt
     4561 caggatacct acgactttgt tctgttcatc aacgaccggc acgtatttca gcccgcgttt
     4621 taaaatgcgt tgcaaggtat cacgaagata ggcggattct tttacgtaaa aaacatgttt
     4681 attcaaaatg tcgccgacac tggatacttt tcctcgtttt ttattcaacg tttctacatc
     4741 gataaatcct tttaatacat tcgaattatc ggtaactaac aacgtatcta cacgtttttc
     4801 cctcatcagt ttgattgctt cttgtaatga tttttccggt gtaatcgtga ttgctgtatt
     4861 tagcataact tcgccgactc ttgtcgcatt tggcttggct tgtagtaggc gatcttctcc
     4921 aatcaactct tctacgaaat cgtttgcagg atgacgtaaa atattttctg gtgtatcaaa
     4981 ttggatcaca cggccttcac tcatgatggc gatacggctt gcta
//
LOCUS       DADVXM010000112         4931 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.118, whole genome shotgun sequence.
ACCESSION   DADVXM010000112 DADVXM010000000
VERSION     DADVXM010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.118"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            85..972
                     /locus_tag="KB927_002481"
     CDS             85..972
                     /locus_tag="KB927_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBB6841361.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="KB927_002482"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="KB927_002482"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBB6841362.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="KB927_002483"
     CDS             2274..2720
                     /locus_tag="KB927_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6841363.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="KB927_002484"
     CDS             2993..4345
                     /locus_tag="KB927_002484"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBB6841364.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="KB927_002485"
     CDS             4516..4803
                     /locus_tag="KB927_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841365.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1393 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt t
//
LOCUS       DADVXM010000113         4807 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.119, whole genome shotgun sequence.
ACCESSION   DADVXM010000113 DADVXM010000000
VERSION     DADVXM010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.119"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..411
                     /locus_tag="KB927_002486"
     CDS             <1..411
                     /locus_tag="KB927_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841366.1"
                     /translation="GLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAP
                     QEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLT
                     ELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            509..1882
                     /gene="tet(L)"
                     /locus_tag="KB927_002487"
     CDS             509..1882
                     /gene="tet(L)"
                     /locus_tag="KB927_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HBB6841367.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            2446..3708
                     /locus_tag="KB927_002488"
     CDS             2446..3708
                     /locus_tag="KB927_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBB6841368.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            3953..>4807
                     /locus_tag="KB927_002489"
     CDS             3953..>4807
                     /locus_tag="KB927_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HBB6841369.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHKK"
BASE COUNT         1660 a          665 c          981 g         1501 t
ORIGIN      
        1 ggcttatact atagccctgt tagtacccca gcagattttc ggatgcttgc tcctattgta
       61 ttggaacaag tcttaaaaaa agctggaaca gaattgttag agccatatct tagttttaaa
      121 atttatgcgc cacaggaata tctttcacga gcatacaacg atgctcctaa atattgtgcg
      181 aacatcgtag acactcaatt gaaaaataat gaggtcattc ttagtggaga aatccctgct
      241 cggtgtattc aagaatatcg tagtgattta actttcttta caaatggacg tagtgtttgt
      301 ttaacagagt taaaagggta ccatgttact accggtgaac ctgtttgcca gccccgtcgt
      361 ccaaatagtc ggatagataa agtacgatat atgttcaata aaataactta gtgtatttta
      421 tgttgttata taaatatggt ttcttgttaa ataagatgaa atatttttta ataaagattt
      481 gaattaaagt gtaaaggagg aattaattat gaagtgtaat gaatgtaaca gggttaaata
      541 caaccaaatt ttaatttggc tttgcgtttt atcttttttt agcgtattaa atgaaatggt
      601 tttgaacgtc tcattacctg atattgcaaa tgattttaat aaaccacctg cgagtacaaa
      661 ctgggtgaac acagccttta tgttaacctt ttccattgga acagctgtat atggaaagct
      721 atctgatcaa ttaggcatca aaaggttact cctatttgga attataataa attgtttcgg
      781 gtcggtaatt gggtttgttg gccattcttt cttttcctta cttattatgg ctcgttttat
      841 tcaaggggct ggtgcagctg catttccagc actcgtaatg gttgtagttg cgcgctatat
      901 tccaaaggaa aataggggta aagcatttgg tcttattgga tcgatagtag ccatgggaga
      961 aggagtcggt ccagcgattg gtggaatgat agcccattat attcattggt cctatcttct
     1021 actcattcct atgataacaa ttatcactgt tccgtttctt atgaaattat taaagaaaga
     1081 agtaaggata aaaggtcatt ttgatatcaa aggaattata ctaatgtctg taggcattgt
     1141 attttttatg ttgtttacaa catcatatag catttctttt cttatcgtta gcgtgctgtc
     1201 attcctgata tttgtaaaac atatcaggaa agtaacagat ccttttgttg atcccggatt
     1261 agggaaaaat atacctttta tgattggagt tctttgtggg ggaattatat ttggaacagt
     1321 agcagggttt gtctctatgg ttccttatat gatgaaagat gttcaccagc taagtactgc
     1381 cgaaatcgga agtgtaatta ttttccctgg aacaatgagt gtcattattt tcggctacat
     1441 tggtgggata cttgttgata gaagaggtcc tttatacgtg ttaaacatcg gagttacatt
     1501 tctttctgtt agctttttaa ctgcttcctt tcttttagaa acaacatcat ggttcatgac
     1561 aattataatc gtatttgttt taggtgggct ttcgttcacc aaaacagtta tatcaacaat
     1621 tgtttcaagt agcttgaaac agcaggaagc tggtgctgga atgagtttgc ttaactttac
     1681 cagcttttta tcagagggaa caggtattgc aattgtaggt ggtttattat ccataccctt
     1741 acttgatcaa aggttgttac ctatggaagt tgatcagtca acttatctgt atagtaattt
     1801 gttattactt ttttcaggaa tcattgtcat tagttggctg gttaccttga atgtatataa
     1861 acattctcaa agggatttct aaatcgttaa gggatcaact ttgggagaga gttcaaaatt
     1921 gatccttttt ttataacagg aattcaaatc tttttgttcc attaaagggc gcgattgctg
     1981 aataaaagat acgagagacc tctcttgtat cttttttatt ttgagtggtt ttgtccgtta
     2041 cactagaaaa ccgaaagaca ataaaaattt tattcttgct gagtctggct ttcggtaagc
     2101 tagacaaaac ggacaaaata aaaattggca agggtttaaa ggtggagatt ttttgagtga
     2161 tcttctcaaa aaatactacc tgtcccttgc tgatttttaa acgagcacga gagcaaaacc
     2221 cccctttgct gaggtggcag agggcaggtt tttttgtttc ttttttctcg taaaaaaaag
     2281 aaaggtctta aaggttttat ggttttggtc ggcactgccg acagcctcgc agagcacaca
     2341 ctttatgaat ataaagtata gtgtgttata ctttacttgg aagtggttgc cggaaagagc
     2401 gaaaatgcct cacatttgtg ccacctaaaa aggagcgatt tacatatgag ttatgcagtt
     2461 tgtagaatgc aaaaagtgaa atcagctgga ctaaaaggca tgcaatttca taatcaaaga
     2521 gagcgaaaaa gtagaacgaa tgatgatatt gaccatgagc gaacacgtga aaattatgat
     2581 ttgaaaaatg ataaaaatat tgattacaac gaacgtgtca aagaaattat tgaatcacaa
     2641 aaaacaggta caagaaaaac gaggaaagat gctgttcttg taaatgagtt gctagtaaca
     2701 tctgaccgag atttttttga gcaactggat ccaggagaac aaaaacgatt ttttgaggaa
     2761 agttataaat tattttccga acgatatggc aagcaaaata ttgcttatgc aacagttcat
     2821 aatgatgagc aaacccctca catgcattta ggtgttgtgc ctatgcgtga tggaaaactg
     2881 caaggaaaaa atgtgtttaa tcgtcaagaa ctgttatggc tacaagataa attccccgag
     2941 catatgaaaa aacagggttt tgagttgaag cgtggtgaac gtggctctga ccgtaaacat
     3001 attgagacag ctaaatttaa aaaacaaact ttggaaaaag agattgattt tctagaaaaa
     3061 aatttagcag ttaaaaaaga tgaatggact gcttatagcg ataaagttaa atcagattta
     3121 gaagtaccag cgaaacgaca catgaaaagt gttgaagtgc caacgggtga aaagtccatg
     3181 tttggtttgg gaaaagaaat aatgaaaaca gaaaagaaac caaccaaaaa tgttgttata
     3241 tcggagcgtg attataaaaa cttagtgact gctgcgagag ataacgatag gttaaaacag
     3301 catgttagaa atctcatgag tactgatatg gcgagagaat ataaaaaatt aagtaaagaa
     3361 catgggcaag ttaaagaaaa atatagtggt cttgtagagc gatttaatga aaatgtaaat
     3421 gattataatg agttgcttga agaaaacaag tctttaaagt ctaaaataag cgatttaaag
     3481 cgtgatgtga gtttaatcta tgaaagcact aaggaattcc ttaaggaacg tacagacggc
     3541 ttaaaagcct ttaaaaacgt ttttaagggg tttgtagaca aggtaaagga taaaacagca
     3601 caattccaag aaaaacacga tttagaacct aaaaagaacg aatttgaact aactcataac
     3661 cgagaggtaa aaaaagaacg aagtcgagat cagggaatga gtttataaaa taaaaaaagc
     3721 acctgaaaag gtgtcttttt ttgatggttt tgaacttgtt ctttcttatc ttgatatata
     3781 tagaaataac gtcattttta ttttagttgc tgaaaggtgc gttgaagtgt tggtatgtat
     3841 gtgttttaaa gtattgaaaa cccttaaaat tggttgcaca gaaaaacccc atctgttaaa
     3901 gttataagtg accaaacaaa taactaaata gatgggggtt tcttttaata ttatgtgtcc
     3961 taatagtagc atttattcag atgaaaaatc aagggtttta gtggacaaga caaaaagtgg
     4021 aaaagtgaga ccatggagag aaaagaaaat cgctaatgtt gattactttg aacttctgca
     4081 tattcttgaa tttaaaaagg ctgaaagagt aaaagattgt gctgaaatat tagagtataa
     4141 acaaaatcgt gaaacaggcg aaagaaagtt gtatcgagtg tggttttgta aatccaggct
     4201 ttgtccaatg tgcaactgga ggagagcaat gaaacatggc attcagtcac aaaaggttgt
     4261 tgctgaagtt attaaacaaa agccaacagt tcgttggttg tttctcacat taacagttaa
     4321 aaatgtttat gatggcgaag aattaaataa gagtttgtca gatatggctc aaagatttcg
     4381 ccgaatgatg caatataaaa aaattaataa aaatcttgtt ggttttatgc gtgcaacgga
     4441 agtgacaata aataataaag ataattctta taatcagcac atgcatgtat tggtatgtgt
     4501 ggaaccaact tattttaaga atacagaaaa ctacgtgaat caaaaacaat ggattcaatt
     4561 ttggaaaaag gcaatgaaat tagactatga tccaaatgta aaagttcaaa tgattcgacc
     4621 gaaaaataaa tataaatcgg atatacaatc ggcaattgac gaaactgcaa aatatcctgt
     4681 aaaggatacg gattttatga ccgatgatga agaaaagaat ttgaaacgtt tgtctgattt
     4741 ggaggaaggt ttacaccgta aaaggttaat ctcctatggt ggtttgttaa aagaaataca
     4801 taaaaaa
//
LOCUS       DADVXM010000114         4806 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.120, whole genome shotgun sequence.
ACCESSION   DADVXM010000114 DADVXM010000000
VERSION     DADVXM010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.120"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(80..1888)
                     /gene="pepF"
                     /locus_tag="KB927_002490"
     CDS             complement(80..1888)
                     /gene="pepF"
                     /locus_tag="KB927_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBB6841370.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2064..3062)
                     /locus_tag="KB927_002491"
     CDS             complement(2064..3062)
                     /locus_tag="KB927_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBB6841371.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3288..3941)
                     /locus_tag="KB927_002492"
     CDS             complement(3288..3941)
                     /locus_tag="KB927_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBB6841372.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4273..4671)
                     /gene="spxA"
                     /locus_tag="KB927_002493"
     CDS             complement(4273..4671)
                     /gene="spxA"
                     /locus_tag="KB927_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBB6841373.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1414 a         1007 c          745 g         1640 t
ORIGIN      
        1 aaaaaatacg tcgactccct tacaagagag ccgacgtatt tttttcgttt ctattcgaga
       61 aaatcaaaaa tagaaagcct tataaacgat cgatcaattc ttctaattca tttagacgtt
      121 gttcaaacat cgacattgca tcttcaatat atgcagcctg tgtcatatca actcctgctt
      181 ttttcattac ttccacagga taatcgctgt tacctgcttt taggtaagcc aagtagttct
      241 ctagtgcctc tggttcctgg tttagtattt tcttcgccag tgctgaagca gcagaaaagc
      301 cagtcgagta ttggaaaaca tagtaattat aataaaaatg cggtatccgt gaccattcga
      361 atttaatttc tgggtcttct tcgactgctg gaccataata ttttgcattc aatttaccat
      421 aactatcact taggtattca ctagtcaatg gcacaccttt ttcatcttcc gtatgcatga
      481 aatgctcgaa ttcagcgaat tgtgtctggc ggaaaactgt tcctttaaac ccatccaagt
      541 aatggttgag tacataagcc cgtacacgag ggtctttttc tgtttccaat aaatactccg
      601 ttaggatatt ttcattcgtt gtcgaagcaa tttctgctaa aaagatggag tagtcgccgt
      661 acacataagg ctggttcgaa cgagtgaaat aactatgaac actatgtccc atttcgtgga
      721 caagcgtaaa tagctgatcc agcgtatcat gccaattcaa taaaatatat ggatttgtgt
      781 catagcttcc cgaagaataa gcaccgcttc gtttcccttt attttcgaca acatcgatcc
      841 aacgttcaga gaatgctttt tctacgatgg ccatgtattc ttcacccatt ggtttcagtg
      901 cttctaaagc tttttctttt gcttcttcgt acgtaaaggt aattggagct tcccctaaga
      961 ccggtgtata aagatcatac atgtgcagtt tttccacttc taataaacgt ttccgtaatt
     1021 ccatgtatcg atgtaacaaa ggcaaatgct tgtttaccac gtctaccaaa gtatcgtata
     1081 cactttcagg aatatgatta ttgctcaaag acgcttctct ggcagagctg taattacgga
     1141 ctttcgcttt aaaattatgt ccttttatat gtgtgcctaa agtagaagca aatgtatttc
     1201 taaattgttc gtaaacactg tacaacccct taaatgctgc ttcgcgcacc cttcgatccg
     1261 tgctttctag caactgacca tacacgccat gagataattg gactatttca ccattttctc
     1321 cttcaatcgt tggaaaaact agatctgcat tattcaaaac agcaaatgta tcacttgaag
     1381 catcaaagat ttcacctgct ccagcaagaa gagattcctg ctcagcagat aagacatggg
     1441 ctcgattatc tactatttgc tggatataat ggcgatagac ttccaatttt ggttcttctt
     1501 tgaaatattg ccaaatctgg tcatctgaca attgcaatat ttctggttca aaccaggaaa
     1561 cggcttcact aactttcgaa aacagactgc ttgctcttgc ataaagcgct tggtaatctg
     1621 tatttccagt gtcttgatcg tttttaaggt gcgcatatac ataaatgact tcagtttggc
     1681 gataaaccct caatacgaat tcaatcgcat ttaaaaattg agaagcgcct tgatcaagtg
     1741 ttcctttgtg tttttcagat tgttttaact cttctgataa ttccaaatat ttctcatcaa
     1801 actcttggtc gcttgaaaag atcttggtca agtcccaagt taaattttca ggcaattctt
     1861 ctcgttttgg caactgcttt acttccatga aatccactcc ttttcttccc ttagctctat
     1921 ctatcaaaat agatcatagt ctaacatcca catgtcacag catctaactt ttctactcat
     1981 tcatgtgtct gcttccatca attttagcat aactaaatct tgttttacat agaaaaccga
     2041 ttcctagcct atttttatac ttactatttt ttcaaagaag acaagtgtat gcattcgtta
     2101 aaaaactgct gatagaccat ctcttcatca atcataggaa aaagccattc ccttttatgt
     2161 tcttttattt ggcaaagcca tgagttgaaa tcaggaactt tctggttttc caaggcttct
     2221 tcgtacaaca ttcgataaag aaaaacctgt tcttgtaaat aaaagaaaaa ccgacttttt
     2281 tgatagatcc acgatgatag atgcaaaaga tgtttatgac gcaagtagca ttgttcttgt
     2341 atggatactg tattcttttg cttgtgaata agttggcgtg tcagccattt cttcccatct
     2401 tcactcactt tttctatttt tttcatttgg ttcattttaa tttcgttact agtgaatatt
     2461 tctttaaggt ccctactaga aaaagtccag cagctactgc aaaaggaaat atgccctgat
     2521 acagtctctg taatatgatg atacaaataa agcttttgtt tcttgagatc agctttccag
     2581 caatgcactc ctctttttct attatagtag cagcaacttt tttctatcaa tgagaattgc
     2641 gattgtccaa gaaaagaatt accaagtatc caccatactt ggtaactgtt attcaaataa
     2701 ttttgggttc tttcaataaa tctctggtga gacagtctag aacattggat ttctattgct
     2761 agattcgcca acaaaatatc cggcctttgc cgcaacctcg gcaaataggc ttccaaaaat
     2821 actggttcta ctgactgtcc cagccaatcc atgaagcatt cctttaactg taagtgctct
     2881 tttgattctc tttcactaaa gaccgaacag ttatctgatt tttgatgggc aaaatgagca
     2941 cattttttct ttcccttttt caaaatcact ctttttcgac agccacgaca ataatatttc
     3001 tttccttttt ctgcatgttt agcaaaacag cacttattat attcattcat tgcaagcagc
     3061 atttttctcc ctctgaactt atttacgtct aagaatttat ttacacgaaa aaagagggcg
     3121 tgaaaaagct attctgcatc aagtaataag aacagctaaa caaaaatagt tcccaatatt
     3181 tttcgtttgg ttgggcttgt taccgcagat gcaagctttt gaacacattt atacgaaaaa
     3241 aagactgcga cacaattttt gtcacagtct cttactataa tgctgattta tacaaaataa
     3301 aatttcgttc gctcgatagc attacgcgcc atcagacatt gtccatattc attcaatgtt
     3361 tctggtgtac gatcgctctt ttcagcaaac tccaaaattc gagcaatctg attctctaca
     3421 tccgcttggt tgagattttc catccagaag tgaacgacta ggtaatagcg ctcttcgaat
     3481 aaatacaaat cagtccaagc agactctagt tcgacatctg ttgcaagttg gatcacttgt
     3541 tcaaaatctt caaaagcaaa agttgcttgt ctttcctgtt cttctagggc gcttccagat
     3601 aattcttcct ccggatcgct gccaataatc tgctgacgaa gaaagtcact cacatcttct
     3661 gaatcaacag tagaatcttc tgattgagaa atttcttcat ccggaagatt tttactgata
     3721 aacagttcta atccgtctcc ttttggcaaa acttggaaag tgacagcttc gcttcctcgg
     3781 aactcctctt cgatatcaac ttcttccaaa atactataaa agaaattttc gatttctttg
     3841 tgattgccaa gtaaatccaa aaatgaaacg ccccgttcct ctaaatcttc atgaccaatt
     3901 agtacacgga tcgtattttc attaatatgt tccatttcca ttttgctaca cctcactttg
     3961 ccacaatgtt taatatagat tcattgtagc gaaatcagct taaatgtaaa gaaaaaaaat
     4021 ctcgctgtta agcgaattta ataaaaccag cggatttttc aacctttcaa gctatcttat
     4081 ttaactataa catttttggc agacgaatac tatatagccg acttttcagc taattttccc
     4141 tctctatttt tcgtgcaatc atcatcttct actacctttt tatacatcta atcaagaata
     4201 ctttttgtaa aaacaaaaaa acttggaaaa actatctttg taatagtctt ttccaagttt
     4261 cgtattatcc ttctataatc cagccatcaa ttgtgcttga cgtaattcta attgtcgtac
     4321 atcgcgcggt aggaaccgac gaatttcatc ttcattaaaa ccaacttgca gacgtttatc
     4381 atcaatcatg attggacggc gaagcaatcc aggattgttt tgcacaagtt ccaataattc
     4441 ttgtaacggc agatcatcta aatccatgtt cagtttttgg aatactttgg aacgtgtcga
     4501 gatgatttct tctgttccgt cttctgtcat ttgtaaaatc gcttttaatt cagaactgtt
     4561 caatggttct gaaaaaatat tacgttcaac aaatggaatc tgatgttctt gcaaccacgc
     4621 acgagccttt ctgcaggaag tacaacttgg ggaagtatat aatgttaaca acgtgcacca
     4681 ctccttttcg tgataagaat cacttttttg taacagaaga tcataataat ctcccatctg
     4741 tttctattat acataatcaa cttttaaata gctacctttt tttcataatt tttttaaaaa
     4801 aatgaa
//
LOCUS       DADVXM010000115         4678 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.121, whole genome shotgun sequence.
ACCESSION   DADVXM010000115 DADVXM010000000
VERSION     DADVXM010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4678
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.121"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            6..2378
                     /locus_tag="KB927_002494"
     CDS             6..2378
                     /locus_tag="KB927_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841374.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIREEIERFEKGESSFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGEFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DQTGQSELQAGIQAVANNIGIQIRDITESEIYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKLSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVQQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2439..3899
                     /locus_tag="KB927_002495"
     CDS             2439..3899
                     /locus_tag="KB927_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBB6841375.1"
                     /translation="MTEKKMSLIDRCKQMDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEAKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLITELKPKHERQNF
                     LVRDNRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVHCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNASFDQQLSVNDSIEAINLKD
                     ICREVAKELKGCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAILFQQGRQQERE"
     gene            3910..>4678
                     /locus_tag="KB927_002496"
     CDS             3910..>4678
                     /locus_tag="KB927_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6841376.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKTTRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYRYHVPKDKKKQFNVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADQGKTYKRLWINSLEKEAIYQGFQQLRDAGETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGISGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKAQVTAQNGTFDAKLDPNETQVTQEAFEA"
BASE COUNT         1785 a          778 c         1011 g         1104 t
ORIGIN      
        1 cggacatggc agaagaaaaa gaaccactag acaatagtcg tttgggaaaa tccaaaagaa
       61 aattagtacg attgcaaaat gaattaaatg aacaaatcga aaagatgttt gaacaccaaa
      121 aaatgacgaa cggtcaacca atgaacgaca agaggaatgg ccgttcatgg tttaaccagc
      181 aagaacgaat cgaaaataaa gtccaaagtc tgagagaaga gatcaagcaa caagaaaaac
      241 aggtagaaaa acttgaaaga caagaagagc taaaggaaat gggttataac aagtacggcg
      301 gactagatat gacgatcgaa aatattccaa gaatcagaga agaaatcgaa cgctttgaaa
      361 aaggtgaatc gtctttttca gccgccacga tccgaaaata tcaacggaag ttggaaacat
      421 tagaacagct gaaagaaaaa tcagaaaaag gaaaagaaaa tatcctccct gaagtacaag
      481 cgatcattga cagcggacga gtaacgcaat ggaaaaaaaa tccgaccatt tattttctga
      541 aaggctatcg aaaagtcgct ttagaactga atgaaaacgg ggaatttgag gaatctaaaa
      601 aataccaagc cacatcggaa gaggaaaaag cagctgttcg tgaattactt gaagaggctg
      661 cgccaactga ttctctgaag gagaaagaaa acgatcattt ctatcgagta gaattcaacg
      721 aaaatgatcc agaaaaagga ttgaaaagtt atggtggaga gatcgtaaca ttagaattga
      781 tcgatcaact caaaacgttg gacaaccaat acgctgcaga agcaggttat tataaattct
      841 attttgaaga agtgaagaac ggagaagtag tcgatcagat ccgaatggat ctaggggatg
      901 gcgtcaacag taatcaaccc atctatttag agttagcaaa attgtgcgaa caagtacctg
      961 agaaggaaca aaaacaaacg gtcaaaaatg aacctgtttc gaaagaacaa atgcagtcga
     1021 aagaaacaaa aacaaaacaa aagggatatc aaaaacgaac ggcagaagag attaaacaag
     1081 aagttaaatc actttcgcaa caggcactgg atgcggtgaa aaagcatacc cattctcctg
     1141 aagacgtcaa agaacttttg aactttatgt ctcgttttcc agaacgatcc tttagaaatc
     1201 aattattgat tgaggaacaa tttccaggtg caacggcttg tttaggtcgt gccgcgttga
     1261 aaaaagaagg aatctatatc aaaaaagggg aacaagggaa caagatcttt gtcagaaaaa
     1321 cggtcaaagg attttatgag aaaggacgtg gctttgttcg agaaacagaa gctacaccag
     1381 aagataaaaa acgaatcgaa agtggtcaaa tcgaagtgat caaaaaacct tactacacga
     1441 ttgaaaaagt gtttgatatc acacaaactc agttaaaacc tgaagactat ccgaaaatct
     1501 tcccgaaccg tgtctttgat tttcaattgg atcaaacagg gcagtcagaa cttcaagctg
     1561 ggattcaagc ggtagccaac aatatcggga ttcaaattcg agatattacg gagagtgaaa
     1621 tctatcaaag agaattagga caagcacgtg gggcgtatgt tcgtaacgaa tttactggcg
     1681 aagaagaaat cgtcatgaat actcgaaata ctcctacgca gcatttagct acaagtattc
     1741 atgaattagc ccatgcaaga atgcacaaac tttcagaatt agataccgca actaaagaat
     1801 tgcaggcaga aatgacttct tatattgtgt gcaaacattt tggaatggac acgtcggaga
     1861 aagctattcc ttatattgca gcatggacga agaatggtca gacgttggat gataaggaag
     1921 ctgcggaacg tgggaaaatc atgaatgatg tcagccgtgt cgcaaatgaa ttcattcaaa
     1981 ccatttctaa tgaaatcaat caatacagag aaagagaacc agagatccaa ccagcagaag
     2041 tgcagcagga gcataaaaat actgtagaaa cggcagaaca aaagaatatt gtgcctgttg
     2101 gttcactttg gatcgacaag aaagacggga aagtaatgga agaagatacg ggtcgaacgt
     2161 tacatttgaa ggatgcggcg tttattgaag atccgcagca taatcaagta attttaaaag
     2221 gaaaaagtta tggaaaagag atccaaacgg cgttaccttc agaagaattt gcgctaggaa
     2281 atccattccg attttcactt gagacagtgt cagaagtggc caaacgaaaa aatgaaatct
     2341 attatgaaca acaattgtca caaaaagaac gcgtataaaa caagtaagaa agactatctg
     2401 aaaaatggat agtctttttt cttttgggag gtttgaaaat gacagagaaa aaaatgagtc
     2461 tcattgatcg atgcaagcaa atggatattg tggattttgc acgaaacaat ggaatggctg
     2521 tagtcaataa aggacgtgac tatcgcttag aagaccatga ttcgtttgtt ttcgatcgaa
     2581 gaaaacaacg tttttattgg aatagtcaaa atattagtgg cgacattatt gaattagcta
     2641 aacttttttt tatagacaaa gagatccaag accctaagca acaatttaaa gcagccactg
     2701 attttattct aaagaatgaa gccaaaacag aacgagtaga aaatcttcat tttgagacag
     2761 aaaagtacaa agatcacccc gttgattatc aaccacttac agaaaaagga aggaattatc
     2821 tgaaggaaga acgaaaattg ccagagtggc tgattgatta tgcagaaaaa gaaggattga
     2881 ttactgaact aaagccaaaa catgaacggc aaaatttttt agttcgagac aatcgtttag
     2941 atcatgcagt tgccttttta tggaaagatc cacagacaaa agagactgtg ggggcgagtt
     3001 atcaaggaac gtttattgat tatgaacgtt ttggtgagag aggaacatat aagcatatag
     3061 ataaaaattc gacagcgaat catggcttta acctaaagat cggtgaccct aagcagttaa
     3121 aattttttga gagtagtatt gatttactta gctacgctgc actgaatcgt gatcagttaa
     3181 acgatacgtg gttagtctct atggaagggt taaaacacca tgtgatcagt cattattttg
     3241 gtgaggcagt atctgaattg agaaagaaac aagcctttcc tcaatcgatt gagatttgtg
     3301 tggataatga tcgtgcagga catattttct acgaaaagga acaattaatg ggcgcagtcg
     3361 atccatttac gaatcagaaa gtacattgtg aacgaggaat cgctaatgat tggcaagtgc
     3421 caaaagaata caaaatcatt tatgaagaag tcgcaaaaga agaaaaggtc acaccagaag
     3481 ctattatggc catacacaag acagaaaaca atctgcaatt aacgaaccaa ctggtttccg
     3541 ctcacaaagt caatgcgtct tttgaccagc agctttctgt taacgattca atagaagcta
     3601 ttaatttgaa agatatttgt agagaagtcg caaaagaatt aaaaggttgt gaacgcgtgg
     3661 atggtacgta cgattttgat cgtttttatc aagaaaaagg ggatattaat gctcagattc
     3721 ttttctctta taaagcagaa caatactaca aaggctataa aaatcatgaa catgaatttg
     3781 tacctgaagt gaaaaaggat tggaacgatc aattgaagca tgagatccag caacaagaaa
     3841 tcagaaagca aaaacgtgcc atattgtttc aacaaggcag acaacaagaa agggagtgaa
     3901 atcgtcatga tgaaaaccgt tattttagca gaaaaaccgt cacaagcgaa ggcttatgcc
     3961 gatagctttt ctaaaaccac ccgaaaagac gggtattttg agatccaaga tcgattgttt
     4021 tcgggagaaa ctgtgatcac gtatggtttt ggtcatttag ttgagttaga ttcgccagat
     4081 atgtacgatg aaaattggaa acaatggtca ttagagcatt tgcctatttt ccctacacat
     4141 tatcgctatc atgttcctaa agataagaaa aaacaattta acgtagtgaa acagcaactt
     4201 caatcggccg acaccattat tattgcgaca gatagcgatc gtgaagggga actgatagct
     4261 tggacgatca ttcaacaagc aggtgcagac cagggaaaaa cctataaaag actttggatc
     4321 aactccttag aaaaagaagc gatttatcag ggattccagc agttacgaga cgctggagag
     4381 acctatccaa aatttgagga agctcaagca cgtcagatcg ctgattggtt gatcggcatg
     4441 aacggtagtc cactatatag tttactcttg cagcaaaaag gcatatcagg aagcttctcc
     4501 ttaggcagag ttcagactcc aacgctttat atgatttatc agttgcaaga aaagattagg
     4561 aacttcaaga aagaacccta ctttgaagga aaagcccaag taaccgctca aaatggcaca
     4621 tttgatgcca agcttgatcc caatgaaacc caagtgacgc aagaagcatt tgaagcgt
//
LOCUS       DADVXM010000116         4588 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.123, whole genome shotgun sequence.
ACCESSION   DADVXM010000116 DADVXM010000000
VERSION     DADVXM010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.123"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(12..482)
                     /locus_tag="KB927_002497"
     CDS             complement(12..482)
                     /locus_tag="KB927_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBB6841377.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="KB927_002498"
     CDS             complement(641..1099)
                     /locus_tag="KB927_002498"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBB6841378.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="KB927_002499"
     CDS             complement(1270..2415)
                     /locus_tag="KB927_002499"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBB6841379.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="KB927_002500"
     CDS             complement(2428..3345)
                     /locus_tag="KB927_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBB6841380.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="KB927_002501"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="KB927_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBB6841381.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
BASE COUNT         1433 a          841 c          870 g         1444 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaa
//
LOCUS       DADVXM010000117         4554 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.124, whole genome shotgun sequence.
ACCESSION   DADVXM010000117 DADVXM010000000
VERSION     DADVXM010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.124"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..1366)
                     /locus_tag="KB927_002502"
     CDS             complement(<1..1366)
                     /locus_tag="KB927_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBB6841382.1"
                     /translation="MLNEKFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFAINIFIQFS
                     FIALSGSRTTLVCLLIATFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAQAWAHVPHITEIKKDISDSSGTTSSNKVDLKRPDTDGGDVSNLRFGLWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKTLRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTI"
     gene            1492..1902
                     /gene="tagD"
                     /locus_tag="KB927_002503"
     CDS             1492..1902
                     /gene="tagD"
                     /locus_tag="KB927_002503"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HBB6841383.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGQFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            2082..3371
                     /locus_tag="KB927_002504"
                     /pseudo
     CDS             2082..3371
                     /locus_tag="KB927_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(3438..>4554)
                     /locus_tag="KB927_002505"
     CDS             complement(3438..>4554)
                     /locus_tag="KB927_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBB6841384.1"
                     /translation="FFDVKYKNLYLIQLIFIVGLTLDISWFFQGIEEFSKVVIRNTVI
                     KLSSVLLIIIFVSTKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPIFNSNVFKQLW
                     KPAFIILTPQLFMQVYTTLDKTIVGYFVDPTELSYYDQSQKIARIILAVLTSITIVML
                     PKISKAQAEGKSENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTI
                     NMLISCLIIVVSPIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVA
                     ATIVLVVVELLVFFFRVFFVRKEIKISYFFGKNVILFFIVNLTLTTWAYYFLPQLFSS
                     SFLDMAIKSIMIFIIYLPFVYFLFPDIRNEIRKITRK"
BASE COUNT         1708 a          767 c          652 g         1427 t
ORIGIN      
        1 atatagtttt ttggatagaa cccagatatc cccaaaaaat aaatgaacct atcgtactaa
       61 ccaaaatgag ttctgtgata aataatgccg aaactgctat tgtaagaatc attaaaatag
      121 caaaaaagtg cttatctttt actagatttg gttgtgtgaa acaataacgc aaagttttaa
      181 agcattggat aaataagaag gttaacaatg tcaatagacc taatcctcct gtagcagcca
      241 taactaagaa aataaaatta tgagcagtta aagtatcttt tcccattaat gtatatggta
      301 gtttatcatg tgcgtattca atatagtatc ctggagaacc gccggatatc ggcttactct
      361 tgaatatttc aattgcactt ttccaaagtc caaaccttaa attagaaaca tccccgccat
      421 cagtgtcagg gcgttttaaa tcaactttat tgctgctagt tgttcctgat gaatcagata
      481 tatctttttt tatttctgta atatgcggaa catgtgccca tgcttgagca gttatatctg
      541 ttacataata catcgcaatt atacttagca atcctactac taatgcagtt agccatcttt
      601 ttaaagtatt agttttaaga aaacgactac tataacttgt aaagaaacta aaaacaaaag
      661 ttgctattaa taaacaaact aatgtggtgc gtgagcccga taaagcaata aacgagaatt
      721 gaataaaaat attaattgca aaaaatattt taaatagaag atttaaatgc ttgtaagtga
      781 ccaaataata tatagcaata atgatgacaa ttaatgatat aaccgcacca aaatttggat
      841 ctgtatatac accaaataaa cggttgccta accaccctaa acgaactggg taatacttat
      901 attttattgg aatttttatg ccatattgaa tgacaaacca gtataatgat actaaattag
      961 ctaaaaacca taccaatgaa agtatccaag taaatacttt gaaaaaaaag ttactactgt
     1021 agtctttgcc aaactgataa atcataaaga aaaagattaa ttgccacatg attaacttga
     1081 tattttcgct atatccatat tttaaattca ttaaactgct tactagcatc gcgccaataa
     1141 aagcaattaa tagccaatca tattttttaa gatttttttc tctaaatgca ataattgcat
     1201 ctataatgat caagacaact cccgctattc cagcaggcca aaaaagtaaa gtatcatatc
     1261 tagtaggtaa tagtaaatac gggcctattg ctcgtaacat tagaataaaa ccaaaataaa
     1321 taaaatacca acctttcaca tattttaaaa atttttcatt caacattttt cctccatcca
     1381 cctatttctc ataaacattt cttatccttt ttaggataaa ctggttcttt caattctaac
     1441 aaaaaaatgc taaactaaca atgtatatta atgaatttcg agaggtgaaa gatgaaaaga
     1501 gtaattactt acggtacctt tgatttgctt cactacgggc atatcaattt actgaaacga
     1561 gcaaaacaat atggagatta tcttattgtt gccctttcta cagatgaatt caattggaat
     1621 gcgaaacaaa aaaaatgtta ttttagttat gaaaaaagaa aacagttact tgaagctatt
     1681 cgctacgttg atttagttat tcctgaagaa aattgggaac aaaaagtaaa agatataaaa
     1741 gaataccatg cagattattt cgtgatgggc gatgattggg ctggacaatt tgatgaactt
     1801 gaacaactaa cagatgcaca agtaatttat ttaccaagaa cacctgagat ctctacaact
     1861 caaataaaga acgaacttaa ttctttaaat agtgataaat aatatttttt aaacaatgaa
     1921 agaacaatat atctggataa gacgtaaaaa aatggctcta taatttctag gactgataga
     1981 attttctgtc gatcctagat tttcttgtaa aaaaaacaga catacaaaaa tttcgataaa
     2041 atagagtcgt ctaaaacatc aatctgaaag gaagattttg tatatccatt tctcgttcta
     2101 tcaaagagca cttcactatt aaagataaaa atattgaaat taattctttt caaaaaactt
     2161 tttataagga caagaaagcc atcgtaatcg aaggtacatt agttcgcact tttagacatt
     2221 gtctattttg taaagaaact gcgaagcagc tcgtgaaaaa cggcaagaag atttcaatga
     2281 ttatcttaaa tcgcagtggg aataaataaa cctatttgcg tcttagaaaa caacattacc
     2341 actaccaatc atgcggaaaa tattttactg ctcatacgta tcttgtcgtt ccttcatgtt
     2401 ttatttcgaa acaagttcat tacacgatat tagaagagtt gaccgagcgt caagcgttaa
     2461 agacacttac gaaacgttgt gatctttcag taacgacatt tcaacggaca ttatctgctc
     2521 tatcggcaat gctgcgacag atgctagact atttacctca ttgtttacta ttcgacgagt
     2581 ttcgctctct ttcaatttcc catggaaagt tctccttttc ttgtatgaat agagagacag
     2641 ggaagctctt tgacattttg tccagccgga gaaaaaaaga tttgattgct tatttcatgc
     2701 gttttacaag aaaagctcat atgggggttc gatacattgt cacaaatatg aatgcccctt
     2761 atttttcatt agtcaaagag tcctttccaa acgcccaaat catcattgat tgctttcaca
     2821 ttggacaaca cttgaacaag tttttcgatc gtgttcgaaa acgtgtgatg aagcagttga
     2881 atcaaaaaga cacttcacaa gctaagtact atcgacaatt gaaacctttg tataaattac
     2941 ttctaaaatc agatgacgag ttggattaca caacattcaa gaaatggcag aattttcaat
     3001 ggcgctattt aacagaaagt gaagtagttg atcgtctacc ctcaatctct tatgaactta
     3061 aaattgctaa gcagtttatc aaaagctgct tagcaattat cacaagaaac agctagctac
     3121 ttcgagaaac gaccaaagaa gttccctcga aacttcacta tctcaaaaag cctttttcat
     3181 atctgaaaaa ggcttttaac tagcattttc gaaaaagtat tctaataaca aaattagaga
     3241 atcttcgcac acatatcaaa acattgaaac gatttgctta tgggtttcgc agttttacca
     3301 atatgcgctt gtggattttt ctaatcaaca ggttaatcag ctatgcatta aaagctagta
     3361 actcttacta actttgttgt tcataaatga ccttatcagc ccgatttgac aaagaactac
     3421 ttttttacaa cattatttta ttttcgagta atctttctta tttcatttcg tatatctgga
     3481 aaaagaaaat aaacaaacgg aagataaata atgaaaatca ttattgattt aattgccata
     3541 tctaaaaatg aagaagagaa taattgtgga agaaagtaat aggcccaagt agtcaaagta
     3601 agattgacta taaaaaataa gataacgttc ttcccaaaga aataggatat ttttatttct
     3661 tttcgtacaa aaaatactct aaagaaaaag actaataatt ctactaccac gagtacgatc
     3721 gtagccgcta cagcgccata agtaggcaca aaagctacat ttccaataat acttacaatc
     3781 gcaccaatga tcattggata agcatactcc ttatcttttt ctatagcaat tgcaaattgg
     3841 ttagcaaaaa ctccaccaat tggactaaca actataatta gacaagaaat aagcatgttt
     3901 attgtcatcg gtttgaaatt ctccccaaaa aaccatggaa caaattcttt tgtattgata
     3961 aacaccacac taaaaagaat taatgcaatg ataatcgtgt aatcaaaaga tttttttgtg
     4021 taaactaaaa tattttctga tttcccctct gcctgtgctt tagatatttt aggcaacata
     4081 acaatagtaa ttgatgttaa gactgccaat ataatacgag caattttttg agactgatca
     4141 taataagata attccgttgg atccacaaaa tacccaacta tcgttttgtc taaagttgtg
     4201 tacacttgca taaacaactg aggagtcaaa ataataaaag ctggtttcca caactgttta
     4261 aaaacattag agttaaagat tggtttacct acttttccgt ggatacttaa ccagaaaact
     4321 aaacttccta aaaagttagt aattgaagta atgaacacgt aaatccacaa atcatcttta
     4381 gttgaaacaa aaatgattat taacaatacc gatgataatt tgataactgt atttctaata
     4441 accactttcg aaaattcttc aattccttga aaaaaccaag aaatatctaa tgttagccct
     4501 acaataaata tcaattgaat taagtataaa tttttatact ttacatcaaa aaaa
//
LOCUS       DADVXM010000118         4456 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.125, whole genome shotgun sequence.
ACCESSION   DADVXM010000118 DADVXM010000000
VERSION     DADVXM010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.125"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..412
                     /locus_tag="KB927_002506"
     CDS             <1..412
                     /locus_tag="KB927_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841385.1"
                     /translation="ITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRYNHNHRGFT
                     CYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSAVDAMNVFV
                     RAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            1702..2625
                     /locus_tag="KB927_002507"
     CDS             1702..2625
                     /locus_tag="KB927_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBB6841386.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            2641..3180
                     /locus_tag="KB927_002508"
     CDS             2641..3180
                     /locus_tag="KB927_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBB6841387.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
     gene            3865..4038
                     /locus_tag="KB927_002509"
     CDS             3865..4038
                     /locus_tag="KB927_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841388.1"
                     /translation="MLKKTVLVLGSISLGILGFSPMLLSVIGKNNSNGELKLNSNYYN
                     SPNEELFVKETDK"
BASE COUNT         1661 a          673 c          758 g         1364 t
ORIGIN      
        1 tattacttgt ctatttttgt tcggtatgat tgttggagca agtactccgt taaatctgtt
       61 tccttttagt gctagaggta taaaagtgga agctgcaagt tcacgatata atcataatca
      121 tcgtggattt acttgctata aaatgaacta ttatgttact aataaaatgt gtagagattt
      181 gaaaaaaaat tataataagc taaagactcc tgctcaaatt gcatctttta ttcctattgg
      241 tggagttgga acatgggtta ttacaaatgc ttttagtagt gctgttgatg caatgaatgt
      301 ctttgtaaga gctgcaaatc aaggaaaagg tgtacaatta acatataatg ctcactttag
      361 caatacaaca tcatatcaat acaatgatta cgctcgttat gtaataaaat aatcagaaag
      421 tgaaactatc tcatgaataa aaagatttta gctgtaatta tttcaataat agttttaatc
      481 actatgttct tcatatttag gctaattttc aatataagct tacaaaaaag tattctttat
      541 ctaattccta tagcatttat cttagcaatt tttagaagta tttacggaaa taaaaactct
      601 aaatagctaa aaataaatca tactaaattt tacaaaaagt ggctagcatt ttctagccac
      661 tttttgtatt gtggagcgtg ggttttgagg gggattcaag ggggagcttg cgcccctttg
      721 acaagcggtt atttgcacca aatacggagg tatttggcta gcaaatatag agcttgccaa
      781 acccttttag tgagttttgt agaaagtacc tttaaaggta ctttcacatt acgaacgata
      841 cgtccgtagg acgtactgaa agggtgggac ttatgagcaa attaatgcaa aatttggcta
      901 gcaaaaaagc taaaaaatat atgctaataa tcgagcgaaa taaacacttt ttcaagtgag
      961 cgaatccgcc atgacaaagc tgaagcagtt tatttcagct ttgtcatggc gtgtgccgac
     1021 ttttttaaaa gtctaggcac acgagcaaat atctttatca agctctaatt tgcgttttaa
     1081 gacgtttgaa acgcctaagt atataaatat ataagaatag gtttaagagt gcttaaatcg
     1141 aattttagag ggcatttaga caattttagg gttgttaggg cttgccctga ccgcctgtaa
     1201 ggcgttttaa gaacaagata agggatttat actaggactg tcttaaaatg tcttaaacga
     1261 acgctcagag cttctcaaag ggttccttat gaacggcttt tagcaaagga gccggaggcg
     1321 actgcgcagt ataatgtgag agcagagcga tcacaccttt ttagcgaacc gtagggagca
     1381 aggtttggaa ttggcagttt tgataaattc gcgaacctgt ttagagaaaa aaggagtgat
     1441 tttttaggcg ggaaaattag cctcccctct ttttatatct ctttttatat ctctttttat
     1501 atctctttta tgtcggctgt gtccttactc tcccaagcaa ttcagagttt tttcaagtag
     1561 gttttctacg cttttcaagt aggttttcta cgcttttcaa gtaggttttc tacgcttttc
     1621 aagtaggttt tccgacatta ttgagtattt ttataaagta tgttactttt atttcatact
     1681 ttataaaagt aggagaagct tatggcaaat gaaattgtaa aatatgaaaa tagattaaat
     1741 catattcctc tgagaaaatt taatagtcgt gaaatgaact tatttttttc aattgcttca
     1801 cgtgtacgtg aaaaaggtgt agatgagatt attttttcat ttcacgattt gaaaaaacta
     1861 agcggttata cagaacgtgg ggaacaattt ataaaagatc ttagtagcac gtatgacaaa
     1921 ttattaagta ttaatgcttg gaatgatgat ggaaatactt taactaaatt tgttgctttc
     1981 acaaaatata gcattatacg agataaacaa cttgttataa tttcagttaa tccagaattt
     2041 aaaggacttt ttaatcaatt aaagaactgg acaagattta atctagagca atttactaat
     2101 ttggatagca catattcaaa aactatgttt cgattattaa aacaatatcg aactcaaggc
     2161 tggactgaat tttccaaaga aaaatttttt gatttactag atattcctaa aagttattgg
     2221 aatagtccgt caaatattga caaatttatc ttaaggccaa ttaaagaaga actcactccc
     2281 ttatttaaag gattaactat tcgtaaaaaa tatggtaaag gtcgaggtaa acctgttatc
     2341 ggttatcgtt ttacttggaa agctgaaatt aaccatgctg acgatttttc caaagggaaa
     2401 caagaagatt tacgtataaa attatttaat attgatcaca atggagaatt aacacgagaa
     2461 gaaaaatggc gcgctaaaga tcgaatacta aatcttccct taggcactca tgaagctgat
     2521 tttaaacaac aacaacaaac tgaagaaaaa caggcagaaa aacgagaact ttcaaacaaa
     2581 ctcaaacaag atttactagg aaatttacaa aacttattcg attaagctta aggagtattt
     2641 atggcagata aaacaatcaa agaacttgcg gaagaattag gagttagtaa aacagcaatt
     2701 aacaaaaaag tttctgacaa aaatcgaaaa ctttggtttg caaaaaacgg aaacaagttt
     2761 gtgattaacg aaaccggtca aaaagctata aaatcaatgt ttttagtcga taacgcaaac
     2821 ttaaatcgaa aactagttgg cgaaaaatca aaaaccaaaa accataaaaa caccaaccaa
     2881 gtttccgaat taaaactcct ttctttccta gaaaaacagt taaatcgaaa agatatacag
     2941 ctacaagaaa aagataatca aataaaacaa atgcaaaaat tactcgacca gcaacaacaa
     3001 ctcactctac aagcgaacca acaaattgag aacctacaag aacagctcca tttaacttat
     3061 acagaagaaa ctccaacaac cgaatcaact gccttttctg aaaaaaaagc agacaataca
     3121 caaccactta ttgaaaaaaa gtggtggcaa atttggaaat ctaatagaac caatctctaa
     3181 aattttctag aagttagttc ggatagtaga ggaaaaagtt gtactacctg atggggagat
     3241 cactcaaatt tttatgagaa agaaaaaata gtttacaact gtaaacaatc aatgtttata
     3301 gttgtaaact atcaaactat atggtgactt attgcttaaa ataggttgaa atctcactca
     3361 atttttggtg gaaaaacaaa ataaattcta atcgattttg ttgaaaaagt cataaaaaaa
     3421 caaatgtgat tttaacaaaa tttcaaaaaa atcgtttgaa atttcgttta ttttttttga
     3481 gaattttgat catcgtaggg tcattgtaga atcattatga gatcatcgtg ggatcatcga
     3541 ataaagtatg ggaaaggctt gcggtgcttg gtattaaggg cattctccgc ctcccaggtt
     3601 cttgaccatt ttctctcaac gtggtaaaaa tcccacttat aagagaaaat ggtcaagaac
     3661 ctaaacggtc ggcgaagaaa acataccaag caccacaagc aaaaaaagtt agagtaactt
     3721 ccaaaaaaga aaaatttttt agaacaactt ttgaaaattt aattttgatt tatatccgtt
     3781 caatttaaac atttgataaa ctgaaggcta gtatttaaaa tgtgtataca agtggtagcg
     3841 ttaaaaaaag tggaggtata acctatgtta aaaaaaactg tgttggtact gggttctatt
     3901 tctctaggaa tattaggttt tagccccatg ctattatccg taattggaaa aaacaattcc
     3961 aacggagaac ttaaattaaa ttcaaattat tacaacagtc ctaacgaaga attgtttgta
     4021 aaagagacgg ataaataata aaaaagactg ctctttcgag cagccagtta aaaaataatg
     4081 agtgtttatt cttgaaaaag caacgcgctt atgaagcgct accaaaaatt tatcatattt
     4141 tatgaaaaat aacaccccag taaaaaatga ctggtaaaaa ttcacaaaga aacggaaaga
     4201 agcaactgca gaaaatcaag ccttaaaaag agcttttgac ttagaccaat cgaaaatcac
     4261 aaagtgagcc cctgtatccc ttggtagaga ggctacttgg catagtgtac attatgtcta
     4321 ctaaccttta aaataacacg ttttataaaa taaaccctct tgacaatatt taattttctg
     4381 attattctaa atatatacag aaagcgcttt cctaggattt tatatctaag gaggaagtaa
     4441 caatgaaaaa taaaat
//
LOCUS       DADVXM010000119         4370 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.126, whole genome shotgun sequence.
ACCESSION   DADVXM010000119 DADVXM010000000
VERSION     DADVXM010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.126"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            157..1080
                     /locus_tag="KB927_002510"
     CDS             157..1080
                     /locus_tag="KB927_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBB6841389.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            1086..2339
                     /locus_tag="KB927_002511"
     CDS             1086..2339
                     /locus_tag="KB927_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBB6841390.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            2473..3819
                     /gene="gor"
                     /locus_tag="KB927_002512"
     CDS             2473..3819
                     /gene="gor"
                     /locus_tag="KB927_002512"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBB6841391.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
BASE COUNT         1503 a          690 c          941 g         1236 t
ORIGIN      
        1 ttttgtcaca atctcttttt atatttggac agaatatatc gaactttatt ttgatttttt
       61 gtgaaataat tttcaaaaat ccgactttaa atagaagaag tattggaaag tttttagagc
      121 tatgctacta ttatgaagtt gtaggaggag aaaattatga tcgaactcat aaccacagta
      181 gaaactattg aacaagcaga acagttgctt gctgcaggtg cagatacact atatttcggt
      241 gaagagcaat ttggattgcg tctgcctgct tcatttacac gagaagaaca gcgacaattg
      301 gtagaattag cacacaagta tggtaaaaaa gcgaatattg ctgtaaatgg gatcattcat
      361 cctgaaaaaa tgaaaaatgt acctgaatat ttggcttttt taaaagaaat aaacgtagat
      421 gtgatcacag ttggtgatac aggtattatt tatacgatga aaaaaaatcc tgaattgcgt
      481 ataccgtata tttatgatgc tgaaacatta gtaacgagcg cacgtcaaat caatttctgg
      541 gcgaaaaaag gcgcagttgg agcagtactt gctcgtgaag ttccttttga agagatgaag
      601 gcgatggaag aaaaactcga tattcctgta gaaacccttg tgtatggtgc tacatgcatc
      661 catcaatcca aacgtccact gctacagaat tactataact atacgaaaca agacgaacaa
      721 aaagatcgtg aaagaggtct ttttatctcg gaacctaaaa aagaagagac acattattct
      781 atttatgaag atagtcatgg cacacatatt tttgccagca atgatctgaa tctctcgaat
      841 gaattgaatg aactttatca gcatcattac tgtacatgga aattggacgg attatttact
      901 ccaggcgaaa aattcgtaaa catcactcga ctattcgccg aagcaaaaaa acaaatttta
      961 gaaggtagct gggatcaaga aaaagcggaa aaaatgacta gcgaaatcag taaattgcat
     1021 cctgaaaacc gtgaattaga tacaggattc ttttatattg atccttctgc tatcaaataa
     1081 ggagtatgat gaaagaaatg acagtaaaaa gaaaattgaa acgaccagaa atcctagcgc
     1141 cagcaggaac actggaaaag ttaaaaaccg cgatccatta tggagcagat gcagtatata
     1201 ttggcgggaa tgcatatggt ttaagaagcc gtgcaggtaa ttttacttat gaagaaatgg
     1261 ctgaaggagt tgcttttgca aaagaacatg atgcgaaggt atacgttgct gctaatatgg
     1321 tcacccatga aggaaatgaa gatggagcag gggaattttt ccgcagtttg cgtgatgtcg
     1381 gtatttctgc agtgattgtt tctgatccag ctttgatcga aatttgtgcg acagaagccc
     1441 caggtctgcc gatccattta tccactcaag cttcagcaac taattttgag acattggaat
     1501 tctggaaaga agaagggttg gaacgtgtcg ttttagctcg tgaagtttca atggaggaag
     1561 tggcagagat tcgtaaaaat acggataccg aaatcgaagc atttatccat ggtgccatgt
     1621 gtatctctta ttctggtcga tgcacattgt ccaaccatat gtcgatgcgg gatgcaaacc
     1681 gtggcggatg ttctcaatct tgtcgctgga agtatggatt gttcgatatg ccttttggtc
     1741 aagaacgaaa cagtttaact gatacaggcg aagtggaaga agaattctcg atgagtgcag
     1801 tggatatgtc aatgatcgaa catattccag aattgattga aaacggcgta gacagcttca
     1861 agatcgaagg aagaatgaaa tcgatccatt atgtatctac ggtgtcaaat gtctataaag
     1921 cggctgtaga cagttatatg gaagatcctg aaaactatgt ctgcaagcaa gaatggatcg
     1981 acgagttatg gaaagtagca caacgagaat tagctacagg tttttactac aatacaccaa
     2041 ctgaaaacga acaattattc ggtgaacgtc gtaaaatccc agtatataaa tttgtcggtg
     2101 aagtattatc ttatgatgag gcaacacaga ttgctacgat acgtcagaga aacttgtttt
     2161 ctgtaggaga tgaaatcgaa ttttatggtc caggattcag tcatttcagt caaaccgttg
     2221 aagttatgca taatgaagaa ggcgaatcca ttgaccgagc accaaatcca atgatgattt
     2281 taactatgcc agtcgcacag ccggtgaaac ctggagatat gatccgaaaa cgtaaataag
     2341 gaaaaagctg atatatccct gttttaagca tcttcgcata caaaattcaa gaaaagtgtt
     2401 acacttgttt tctgtagaaa aaggatcgtt aaataaaggt tttgattgat ctcttcaata
     2461 aggaggaaca aaatgcaaat atatgattac atcgtaattg gtggcggctc tggcggtatt
     2521 gcttcagcaa acagagcagg gatgcatggc gcaaaagttt tgctgattga agcgaatgaa
     2581 ttgggcggaa catgtgtcaa cgtcggttgt gtacctaaaa aagttatgtg gcaagcaagt
     2641 acgattttgg aaacaattga acgagatgcc tcaagttacg gtatccaagc agatttaaaa
     2701 aatgttgatt tcgccggtct agtagaaaga cgagaaaaat atattgattt tctacacggt
     2761 gcttatcaaa gaggattaga tagcaatcat gtcgaggcta taaaaggtta cgctactttt
     2821 atcgatagtc aaacgatcga agtaaacggt gaaacctatc gtgctcctaa aatcttgatc
     2881 gctactggag gccgtgcaag taaaatgacc attcctggtg gagaatacgc aattgattca
     2941 aatggatttt ttgaattaac agagttacct aagagagcaa tcgttttagg tgctggatac
     3001 attgcggctg aactttcagg tgtatttcgt ggtttaggta gtgaagtcat gtgggcatat
     3061 cgaaaagaac gaccacttag aacgtttgat aaaatgcttt cggacaattt gatccaaatg
     3121 taccaagaag ctggaataaa aacttacgca catcatattg ctaaagaaat tactaaaaac
     3181 aatgacgaat atacggtgct atttgaaaat ggtgaaacct taactggtga ttgtgtactt
     3241 tttgccggtg gacgtgtacc gaataccgaa aaattaggtc tggaaaatac aaatgtggaa
     3301 ttggacaaaa aagggtttat caaagtagat aaataccaaa atacaacgga tgaacatatt
     3361 tttgctgttg gtgatgtgat cggtaaatta gatctgactc ctgttgcaat cgcagctggt
     3421 agacgtttat cagaacgttt atttaatgga aagaaagatt cttatcttga ctataaactt
     3481 gttccgacag tcgtctttac gcatccacca attgcaacaa ttggtttgac agaagaagaa
     3541 gcattggaaa aatatggcga aaatgaattg aaagtttatc gttcacgctt taccccaatg
     3601 tactttgcat taaatgatta tcgccaaaaa tgcgaaatga aattgatctg tgtcggaaaa
     3661 gaagaaagaa tcgtcggctt acatgctatt ggtgttggtg tcgatgagat gctgcaaggt
     3721 tttgccgtgg ctatcaagat gggtgcaact aaagaagact ttgacaatac agtagccatc
     3781 catccaacag gagcggaaga attcgtaacg atgcgataat ttaatattaa cagttccaac
     3841 agctttttat tgaacaaacc atgtaaaacc agaaaatcag tatactgatt ttctggtttt
     3901 ttgtttttta gttatttatg taagattgct tcgataattc tcaaaacgaa ataagtaggg
     3961 aagttggaga ttttgattat cttcgtaact gacgaagagt aaatgaatcc atttggtatg
     4021 cactcttaag ttcaaaatat tggtatcgat gtttaaaaga aatagaaatg tatcgaagaa
     4081 cagatgttta aaaaagtgtg actttgtata aataaattag aagaagcaaa cgaggatgtt
     4141 aaaagaatac catatagtta ccaaaccaag aaagttctcg tcaagttcgc tggtacgaat
     4201 caaatcaagt gaaaaaaggg actgtgaaaa aaattgtgtc atagttagtc actttttccg
     4261 aacaaatagt gttcaatcag ctgtccttcg gtattagctc aaaaaacggc aaaatatgag
     4321 gaactatttt tccatttgtt tctctaatac tcaggacaaa acactgattt
//
LOCUS       DADVXM010000120         4302 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.127, whole genome shotgun sequence.
ACCESSION   DADVXM010000120 DADVXM010000000
VERSION     DADVXM010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.127"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            56..1357
                     /locus_tag="KB927_002513"
     CDS             56..1357
                     /locus_tag="KB927_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6841392.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            1384..1644
                     /locus_tag="KB927_002514"
     CDS             1384..1644
                     /locus_tag="KB927_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBB6841393.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(2643..3878)
                     /locus_tag="KB927_002515"
     CDS             complement(2643..3878)
                     /locus_tag="KB927_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBB6841394.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
BASE COUNT         1254 a          689 c          885 g         1474 t
ORIGIN      
        1 ctttgcgttg tcatgcaatg aatggttcat attttattga aaaggagtgg ttttagtgga
       61 aaagctgatg aaatgggtcg aagagaaact tgtcccacca atggcaaaaa ttggtacaca
      121 gcgtcattta ttagcaattc gtaatggggt tgtttcaaca ttgtcattga ttttgattgg
      181 gacatttttt atggtcttta tcaatttacc gtttcctgga tggaatgaat ttattgcccc
      241 ttattcggca acgattgttt taccctttag gatgacgatg ggattgatgg ctatttatgc
      301 aacttttgtt atgggttcgg atctagctaa atcatatgga ttagatagtg tgacaggtgg
      361 tatattatct ttaggaacgt tctttatgtt acaagttcct gtaaacgttt taactcctga
      421 agaggcacct cttggctggg tcttacctat gagttctttg ggagcatctg ggatgtttgc
      481 ggggatctta tctatgattt ttgcagtgga agtatatcgt ttctttaaaa atcgaaatat
      541 tactatcaaa atgccagaac aagtgccacc tgctgttgcc cgtagttttg aggcattgat
      601 tccaggtgca gtcattttaa caattacttg gctgattcga agcgtcgcgg gctttgatgt
      661 aaacgctgcc ttattatcgt tattcgagcc tttaaccaat attttaggga ataatttgct
      721 tggtgtttta ctaccaatgt ttttgatcca tttgttgtgg tcatttggta tccatggcat
      781 gagtattgta ggggctgttg ttcgtccaat gtggctgatc atgttggatg agaatgcaaa
      841 ggcattggca gatggtacag ctgccaccca attaccctat atcgctcctg aacagtttta
      901 tcaatggacg gtaacaattg gtggtgcagg agcaacgatc gtggtatctg ttttgtttat
      961 attcttctgt aaatcaaaat tcttgaaaga ggttggtcgt ttttctatta ttcctggtat
     1021 cttcaatatc aatgagccca taatttttgg agctcctatg atgttgaatc cttacatgtt
     1081 catcccgttc aacttagttc ctttagtttt gactattatc agttattttg cagtcaaatt
     1141 agaaatggtc aatagattta ctgttttgcc aacatggaca ttaccagctc caatcggcgg
     1201 ttatctttca gcaggaaatg actggcgtgt tgttatcttg atcatgatca acacattgat
     1261 agcatttatt atctattatc catttgtaaa agcttatgat aaaaagatgc tgtcagatga
     1321 acaaagtcgt ggagaaaacg aagtccagac tgtctaagtt tggtttttag aaggtgggaa
     1381 acaatgtatt ggctgatttt attttttgtt tttatctttt tattaacggc tagtcacctt
     1441 atattgaata tgctagctac atatcatatt caaatcaatc gatggatttg ggcactggca
     1501 tcatttttga tcgtgattct tccaaagatc attgtaccgc atatgaatgt tttgttttca
     1561 tgggggacat atgtactttg tggaattttt gctatcaatt ttatgatcga gcagcataga
     1621 tggtttgtca catcgaagct ttaaatgttc taaaagtggt tgtaacagaa gtggttagct
     1681 tcaagaaata agaagaaatt tacgaaaatt gcttcttaaa tttttgtgaa atgttggctt
     1741 atttttcgtt tggttgaact tattaccgca gatgcaagct tttgaccacc gtttattcgg
     1801 aatatgggac tgtgacaagg cttttgtcac agcccttttt tacataaaga ttattattgt
     1861 tttaactgtt ttggcagaaa gaaggaggaa aaaatggaaa ttttatcagc aatggattta
     1921 gaattagtag atctactacc aaagtgatca agtcaaatat agatttggga gcttacaacc
     1981 atatagtagg ggctgcagta tggtgtatga atggtaatat gtatgatgtg agtgtttatt
     2041 caaatcatga aacgtgtata gaaataattg tgctgggaat agcaatcagt catggtgaac
     2101 gtgactttta gtgtatcgtt gctgacgaca tagaacattc tgacatgatc tactcaatat
     2161 gtggggattg ctggcagttt atataggagt atgcatcgga ttgcgagatc attgtctcaa
     2221 cagaagaggg aggttgatta tcaaagataa agtggtaaat cctacatttg atttagtaat
     2281 tgttgagggg actagcggca caaatctcta caaagcgatg cttctagatc tatatgacac
     2341 attttaagaa aatgtatttg cctaattatt atggtctttc ttttgaagaa acgttgagat
     2401 gatccaacca gagaaaggtg tcaaagaatt tgactaagaa taaatggcag acgctaccta
     2461 tgctcatttg gatagcgtca gatcttttat tttaaggatg attttgtgtt ttttagacac
     2521 cgtaatttaa gtaactctaa cttttcaatc cactatttac tttttttgta ttttcactgt
     2581 ctgggtctcg aatagcgaaa ttactgatga gtctctatta aaaaagcttt ttctacttga
     2641 aactatattg ggtggttgct caggaaggtt tcgatttctt gaattgcttg ttgtggacca
     2701 tttattggaa aaacggcttg cagcgtgcgt gcctgctgac gaatcttggg tgaagaaact
     2761 tcgcgcagag caatctgcag ttttctttca gtcactggtt ttgtgagggc gattgcgttt
     2821 ccgtatttta cacaatagtc aatattacag ctttgctcaa attgcatccc cacaccgata
     2881 aacggtttgc cggattcaca ggcagtttgg acggtccctt ccccgccgtg gataaaagaa
     2941 aaatcaatga attcatgcaa aagatgacta gacagatatt ctgttattaa aagatcttct
     3001 gagtcagatt gaatgtcatc aagcagatag tcaataggtg caataaccgc tagatccggt
     3061 tgtttttgta agaagaacaa aattttgcgt aacatacgcg gattgcctga actacccatt
     3121 gcgaaataga taatacgttt tctttcttgt tgctttcgct gtataaaagt tagcacttct
     3181 tcaggcaagg aagtactgag cttagcaaaa attggaccaa cgattcgata attttccggc
     3241 agctgttctt cttccaaaaa tagtttaggc gttgtgatga gatttagatc agcatccatc
     3301 atttgtaaac ttgtttttgg taaaggaagc atttcttttt gtgcagcgtg tttgaaggca
     3361 ttggggatcc atcgggtatt tactatacgc ttttttgtcc agtgccaaag gggattgctt
     3421 aaagggccga agaaacgtaa ctcgtggggc atcagcgcat gctctgattg aaaaaaaggt
     3481 tcactcaaag catagggttt aacatatact aaaggaatct ttttattgcg ggccgataaa
     3541 aaaattgtca cattcgaacc tgtcacaatc agtcgaggct caaacttagc aatcagactc
     3601 tgttcactag tgatacgaga ggcaaccatt tctttggtaa aagggttttt aagtgtacgc
     3661 aactggtcaa attttatgat ttgttcttct tgttttttcg taaggatcgg cgctagtaaa
     3721 tgatactcaa agccactttc tgtgatcaaa ggagcaaaag ttttagaaaa gccaaagaat
     3781 acacagtaat aacggtcttt catagctttg gcaacctcaa tcattcgtgt tgtctcagct
     3841 aaattgaata ctgcaggagc aaaaagaatt gtcttcatga aatcctcctt attggaatga
     3901 gtctatccct tcgtttctta ctagtatact aaaaaacaca gcgttcgagt agcctatgta
     3961 tattttgaat attaaactgt ctctcgctgt tttcacaact tctaaattta aattttgtaa
     4021 tcaagttgaa actccaattt tcaaaaaaac acgcaacaat tttttgatcg atttatatgt
     4081 tgtgccagat aaatacgaga agttgtgtca ttaaaaataa acatgagaac ataaaaaaat
     4141 aaaataatta tattaattga taggtgtgct gtcgtcatta tacacacgta agaaagaaat
     4201 agttatgttt aaaaatattc ttagactttc tcgccatgac aattttcact atgtgttata
     4261 actgtaaacg ataattattc agataacaca aaaagaaatc aa
//
LOCUS       DADVXM010000121         4295 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.128, whole genome shotgun sequence.
ACCESSION   DADVXM010000121 DADVXM010000000
VERSION     DADVXM010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.128"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            227..826
                     /locus_tag="KB927_002516"
     CDS             227..826
                     /locus_tag="KB927_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6841395.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            875..1591
                     /locus_tag="KB927_002517"
     CDS             875..1591
                     /locus_tag="KB927_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBB6841396.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            1605..2384
                     /locus_tag="KB927_002518"
     CDS             1605..2384
                     /locus_tag="KB927_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBB6841397.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
     gene            2467..2823
                     /locus_tag="KB927_002519"
     CDS             2467..2823
                     /locus_tag="KB927_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBB6841398.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            2813..3079
                     /locus_tag="KB927_002520"
     CDS             2813..3079
                     /locus_tag="KB927_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6841399.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            3238..3516
                     /locus_tag="KB927_002521"
     CDS             3238..3516
                     /locus_tag="KB927_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841400.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
     gene            complement(3513..4194)
                     /locus_tag="KB927_002522"
     CDS             complement(join(3513..4160,4162..4194))
                     /locus_tag="KB927_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBB6841401.1"
                     /translation="MNHFKGKQFKKDVIIVAVSYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLDYLWKKKNRQSFYSWKMDETYIKIKGHWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRSIKRRHKLYQSLRTASTTIKGMETIRGIYKKSRKEGTLFGFSVCTEI
                     RILLGIPA"
BASE COUNT         1531 a          656 c          821 g         1287 t
ORIGIN      
        1 ttttaaaggg gcaatattaa tgttctgaga taatcaaatc ttaccgaaaa tatcaaaagt
       61 ccaatgtgac acaattggat tttgtcacat tcgttaaaat cgctccatcc ttagaggctc
      121 taataggaaa tcacttttct tttagcgcct tttttctata gcttgtttaa atgtgactta
      181 ttatctgtta taatcgtatt aagtaacatt tgagaggtgt ctaaaaatga aaagcgtgga
      241 accgattcgc gacaaaaaaa agatcgatgc catgaaggcc attttggctt ccggaaaata
      301 tgggcaacga aatttggtgc ttttttcgat cgggatcaat acagcctatc gaatctccga
      361 tttaagacag ttaaaattaa gggatgtgct agaaatttcc cgtgggcggg tgatcgtcaa
      421 agaacgtctg gccatgaagg aacaaaaaac ggccaaacac aattcggtct tcatttcgaa
      481 caaattgcga aaagtgattc ttgattatgt tcaatccgaa tttcctgagc agttgcaagc
      541 acaagacttc agcaagtatt tgtttccaag tcgaaaagga gcagatacgc ctttgacccg
      601 acaaagcctt tggcggatca ttcatgaagc aggaactgca gttgggttaa aagaaattgg
      661 tccccattcg atgcgtaaga cctttggcta ttttttatac aagcaaggaa ccaaaacaga
      721 gatcattcag tcgctgctaa accattcttc acaacgggag accttacgct atattggaat
      781 cacccaggaa gacaaagata ctgcagtaaa gagtttggat ttatgacaga ataatgccct
      841 atataataga aggaaaaatt caagaggtga gaaaatgaac gaagaaaagc agcctaactt
      901 tcctgataaa tatcacttat ctcgcaaaga gtctgtgtat ttattgaaga aaaacattgt
      961 agaactggtg tataatgcgg ggaaatttga agggttaaat acaacgttgt tacaaacaga
     1021 agggattatt aagtataatc gggccaacaa cgtggctgta gatgatgtcc tgaccgtcgt
     1081 taacttaaaa agaggctttg aaatgctttt aaatgacgta caggagcccc tgttagagac
     1141 aagtaagcgg attaatcgga tcgttgcagc agaggatgcg ctttttcccg gtgaaatacg
     1201 aaccggtggg gtagaattat cgacgattca aggaagatat gtgccaccaa tgttaactga
     1261 agacgaggta aacaatcaat atggtgagat aatgaatcaa gagatatcag atacggaaaa
     1321 agccctgcga ctgtttctat tcatttcgaa aaatcaaata ttctggaatg gtaatgtggg
     1381 tacagccttg ttgattgcga ataagattat gtttagcaac ggtttaggac tattatcaat
     1441 acccgaaaat gtatttatga aatttaacga acttttatca aagtattgca acagtaatct
     1501 attagtcaat gagtcaaata ttatatcatt tttatatgaa cagtgtatct ttggtattaa
     1561 ttatttgaaa ataatccaac atacaattta agaggtataa gtaaatgatg actatagacg
     1621 aagcaaaaca attagcaact tatttttcag ttggttcagc gggatatatt ttagacttta
     1681 ctaatgtaac gtggaacata tttacaaaga aaatcgtagg gattgaaata caaaatcatt
     1741 atgggggctc aaagggagta tcctttcaaa agtttctgct tgacgatcaa tttgatgatt
     1801 cgttaaagaa tcggttaatc caatctttaa aaggtattat ggatcgagat aaaaaatatg
     1861 aatctactga aatgaatccc atagttcagt tgctttttga ggaagtattt aaagaagata
     1921 cttcaactgc attaagaaaa atgaaatttt caagcgagat tgatttactt tatattcggc
     1981 agctacccat taggattcaa acagatatta aaaacaagga ttttgactct gttttgacaa
     2041 aagcaaatac tttaatagat gaagttctaa aatttattat tgaaaatacc gaaggaccga
     2101 gtgttaatat taatttattt aagtcaaaag aattaagaaa agaagtattt ggccgcctca
     2161 atattaaaac tgaaaaagat atggataata gaatcaaagc ccttgttgga gcactcaata
     2221 cattatcaga taaaatactc gaaatgagaa atagtcaagg agatgctcat gcacatggct
     2281 caaatagaat agtaattaag gaagaagaag caattcttgt tgcaaattct tctatggttt
     2341 tgtgcgagta tgtgtttact aagtataaag gattaaatag ataataaaat gcatatttta
     2401 tagtatacaa ttcgaatttt tatgttatat actataatat aaaatcaata tatgatataa
     2461 ttgggtatgg aaaaaatatc ttttgaaaca tttaaaagac ccaatggtca tgatgaattt
     2521 ttagaatggt tggaaacatt accaaaaaaa gatagtgcga agcttttacg tacaatagaa
     2581 gaaacagaaa agaatgggat gctagtagct caacggttga aatgggtgaa aaaattagac
     2641 actaatttgt acgaattaag aagtaaggta ggatcaaaca tccaaagagc catctatttc
     2701 catgtggaca atggaaggta tgtcattact cacggattta ctaaaaaaac ggagaaaaca
     2761 ccaataactg aactcaagca tgcaaaagaa cttagagagg agtggttcac aaatgatgat
     2821 taaaaaattg attgaagaaa agaaaaaaga taaagatttt gcagaagcat atgaccgtga
     2881 aggaagaaaa ctcgaaactg cggttgctct ttatcatgct cgggaggaag cagggctaac
     2941 tcaagcggag cttgcacaaa aagcacatac aactcaatct actattgctc gaattgagag
     3001 aggggataac gtatctttcg ataaacttga tgatatcgcc agggcattag gtaaaaagct
     3061 ggtagtagaa tttgcttaaa agcgagttga aaatatatct ataataggct cctaactaat
     3121 caattagttt agtgggcctt tttttactag atagataaag gttgtactat agtgtaaaag
     3181 acaataaatt ttatactaaa attactttaa agagaactag agagaaaggt acaataaatg
     3241 aaaaccataa atcttataaa agtatttata gcatcaccag gtgatatagc agcaaaaagg
     3301 aatgaagtag aagaaaccat atatagatgg aatatagaaa atacagataa tacaaaagtg
     3361 attttgatgc ctatacgatg ggaaactaat gcgattccta cttatgtaaa taatagctct
     3421 gggcaaagtg ttattaataa acaaattgta gaaaataggg ttctgctgca aagttttaaa
     3481 aataaaatca gtttttgtat tatttcttca ttttaagctg gaattcccaa taatatcctg
     3541 atttcagtgc agactgaaaa gccgaagaga gtgccttctt ttcggctttt cttgtagatt
     3601 cctcgaatgg tttccatccc tttaattgtg gtggaagctg tacgtagact ttgatacaat
     3661 ttatgtcgac gttttatcga tcgatgatct tgttctatta aattgttaag atacttcaca
     3721 gttcggtgct ctgtcttagt atataaaccc acactctgta actttctaaa ggcggagcca
     3781 agagaaggtg ctttatcggt cacaattgct ttcggctcac caaactgttt atggagtcgt
     3841 tttaagaaag cataggctgc ttgcgtatcc cgtttctttc gtaaccagat atctaaggtt
     3901 aagccgtccg catcaattgc acgataaaga taatgccaat gtcccttaat tttgatatag
     3961 gtttcgtcca ttttccatga atagaaggat tgtctatttt tcttcttcca aagataatcg
     4021 aggactttgc tgtactcttg cacccaacga taaatcgtag tatgacaaac atttattcca
     4081 cgatcatata acaattcctg aacttcacga tagcttagat tgtaacgcag gtagtaacta
     4141 acagcgacaa taatgacgtc attttttgaa ttgtttgcct ttaaaatgat tcattactct
     4201 atcctctctg tcttttttct caattttaca ctaaaataga ttttttggaa aactttgcaa
     4261 cagaaccact tttcgtaata tcaatgtctt tattc
//
LOCUS       DADVXM010000122         4290 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.129, whole genome shotgun sequence.
ACCESSION   DADVXM010000122 DADVXM010000000
VERSION     DADVXM010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.129"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(67..252)
                     /locus_tag="KB927_002523"
     CDS             complement(67..252)
                     /locus_tag="KB927_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841402.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            467..838
                     /locus_tag="KB927_002524"
     CDS             467..838
                     /locus_tag="KB927_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6841403.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(988..1060)
                     /locus_tag="KB927_002525"
     tRNA            complement(988..1060)
                     /locus_tag="KB927_002525"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1025..1027),aa:Gln,seq:ctg)
     gene            complement(1106..1534)
                     /locus_tag="KB927_002526"
     CDS             complement(1106..1534)
                     /locus_tag="KB927_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841404.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(1594..2352)
                     /locus_tag="KB927_002527"
     CDS             complement(1594..2352)
                     /locus_tag="KB927_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBB6841405.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            2647..2844
                     /locus_tag="KB927_002528"
     CDS             2647..2844
                     /locus_tag="KB927_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841406.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            2950..3432
                     /locus_tag="KB927_002529"
     CDS             2950..3432
                     /locus_tag="KB927_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841407.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3490..4086)
                     /locus_tag="KB927_002530"
     CDS             complement(3490..4086)
                     /locus_tag="KB927_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6841408.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
BASE COUNT         1336 a          689 c          819 g         1446 t
ORIGIN      
        1 aagaaccaaa ggaggacgat gcagcagcat tgtcctcctt tgattttaca aaagtgaaag
       61 ttttacttat ttgaatagat ttttaaattt gtttttgaca ctgtcgatat ttacatcttt
      121 taaaagattt tgggctttct ctttataagg tcctaattgt tctttatgtt cttcgataaa
      181 tcgttttgcg ccatcgaaat tgccgttctt aatcatttcc ttgacttttt gaaataattc
      241 ttcttgattc attttgaaca catcctttgc tatcaacatg attttttaca tggacaaaac
      301 gagaaaaact gatttatcca cacgtcaata atatcaaata acgatcattt ttactaaaaa
      361 aacactcgat tctcgcttct aaagtaggag aaaaatctcc aacttgggac ggatggaatt
      421 tctttaactg acccatatac tgaatatata acaaggaggt agaaagatga aagtgattaa
      481 atatttgatt ggactggcgg cgattagtgg tattttgcta tttggactga aatattatac
      541 tgaaggaagt tatggagaaa tccctggtat acttgatcag ctaaatccat tagttgaaaa
      601 aggagaggtc tatgtaaaga cacaaaaacc agaggaagta aatgaatatg gtacagcaag
      661 gtatgtgcag aaagctgctg atgccaatgg gaaagaacga acggttgaat ttaatggtct
      721 ttctgtgtta aaagaaaatc attatttgaa aattagcaat aaaggagcac acatagaaac
      781 gtatgaggaa gttcctagag aaaaagttcc ggagaaagca ttagcaatta ttgggtaaat
      841 cagtttttgt attaagaata cgcccgattt tattattcat aatttaatta tgtaaactaa
      901 atacaagtag taaaaataat acaataatcc ccctgcaaaa agattgttct tttacagggg
      961 gttcattttt tcagcaagca catcaaattg ggatggcagg gttcgaacct acaattgctt
     1021 gattcagagt caagtgcctt accagtttgg ctacatccca tttattcaac aaaataatca
     1081 tagcactttc ctaaaaaaac gcaagttatt tttcttgatc ggatagttgt tgctttactc
     1141 gtaaaaggcg gcgtactagt ttcttttcta atccagcagg aagggcaatc agttctgcta
     1201 ctgacaagac ggtgtccaat aactgatatt ctttgacagg ttcattcata atatgataga
     1261 tgtttgctaa acgttcaata tattcaaagc gagtatactc tgttcgagca attagaaatt
     1321 tcaataaatc ggtggctttc tcgtactctt gatctgcgta ataaacaaga gattgacgat
     1381 acaatttgat ttccagttca ttgagggtag caggtctgcg acgctcgttc cactcattaa
     1441 tagagacttt accttgaaca tttcccttgc agtcacggac aaaaataatc ggaatttcat
     1501 ttggatccat ttttttatgt gtgaattttt ccattatcta cgctcccttc aaaggtttgg
     1561 tatcttgagt ataagggatt tttgtttgaa ttactagctt ttctccaaag ttagcatctg
     1621 tccacccatt gcagtgaaaa tcgccgaaaa atcgttgatc ggtactgctc gattttttac
     1681 accataggga tcgttgacat aaatattttc tttgtcatat ccagtgacta cacaagcatg
     1741 aacaagagga gtgactctta cttctccatt atttgtggtc caagtcataa aatcagtttc
     1801 atctgggact tcaaaattga tagtcacaga agtccagaca ggatttcctt tagatagtgc
     1861 ttttttgata tcatcgagtt gagcatcggt ttttggaaaa gtgtgataat ccgtttggac
     1921 gatttgctga gcaagggagg caactggggg aacatagacg accatagccc agtctccgcc
     1981 actgatatca ccaacaaatc cttcattagg atcgccatga gtcccatctg cattgaaaac
     2041 agggacgtaa tccaattgct cagctaactg gtttttagtt gtttcataac cataaaaaga
     2101 taaaagcata gaaagcgaag tgacttcaca gccattttct aaagaaggag aatcaaactg
     2161 gctctctaat ggaacatcta gtaaaacttc tgctttctct tttgtctttt tcgttttttg
     2221 tgttgaactt ttttgtgcag tgttcattgt atgttctgga gaatggatat gtaggtaata
     2281 acttgtaccg cttaataaaa gagcagctgt gccccctaga aacaatagtt ttttgaacgt
     2341 ttttttcttc atttgaaatc tcccttttca gctgtttatc tttcctatta taaatgtatt
     2401 tttattggaa atggaagtat tatattttaa tatgtaggaa ataattagtt tttaaggaat
     2461 atgttttaat tttttgaaaa aaattcttct aaatacaaca gctgttttaa ttgtgaaaac
     2521 gaaaacagta cgctataatg cctgtaaggt tgatttttaa ctgtaaataa aaatcaatga
     2581 gttaaatctc caaagaaata gcagtggtaa tgtggagaaa agttccagca gtttaggagg
     2641 attttgatga cggaagaaat gattaattta ggagaacaat atgcatgcaa accaattggt
     2701 tttacaaaaa cggtcattgg tgaagttgta tcaaaaatga caaactgcgc cgtggtcaaa
     2761 gttgcccaat gtgctgcaga ggaccaagaa ttattagatg aaaaagcaag catggttgtt
     2821 gcaaaatatg atacatttga ataaagaaaa caattggacg tgcggcgtgc tgcaagtcca
     2881 atttctttga gaaggtaaat cagtattctt ttcctatttt ctggagaaga aaaagcgagg
     2941 cgagttgtca tggtaacatt ctttacggtt ctattgtttt tattcgttgt tgtgatgttt
     3001 ttatttcttt ggctggttcg aaaagaaatt atttatcgga ctgtgcgaaa tcgatgggtc
     3061 tacttggtga tacccttctt agtgtcacta gtcatttggt atacactcat cagtcatcct
     3121 acagcagatg aattggcaaa agggatcttg tcagcaatga tttttattag ttttttgttg
     3181 gacagtagag gaatcacaga agaaggactt gttttgaata gctttgacaa aaaaggtgtt
     3241 cctttttctg agatcaataa aattgtatta tatcagccaa aaggttctaa aatcgtaaaa
     3301 atgaattttt tccgaaacgg atggcgagga ccgatgctga aattttctgc atcattagaa
     3361 gaattagttc catttttgtc ccaacgctta aacgatgagg cagagattga tattatgatt
     3421 gatccagaat aaaaacagag gttgcgacaa gatgtttgtc acaacctctg ttttttattt
     3481 caaataaaat tatccaaata cgcggaagcg atcggcatcg ttcatgtatt ctttttcccc
     3541 agccggtgtt tctggtgaac cgaatactaa ttgcgaacgt agtttccagt ttgaagggat
     3601 attccattct tttgcaactg cttcgtcaat aactgggttg taatgttgca agtttgcgcc
     3661 caatccttta tcaactaatg ctacccaagt attagctgtt gcgattccgt ttgattgttc
     3721 tgaccaatct gggaagttgt ctgcatataa ttcaaattgt tcttgtagac cttttaccac
     3781 gtcagtatct ttgaagaata atactgtacc ataaccattt ttgaaaccag ctaatttgtt
     3841 ttgtgtattt gggaaagctt ctgctggagt caatgggcga agtgcttctt cagtgatttc
     3901 ccaaagtttt tcatgtgcat ctccgaaaag gataactgcg cgtgttgatt gagcattgaa
     3961 agcagttggg ctttctttaa ttgcttcttt gatcaaagtt gttaattctt cattagaaag
     4021 tgaaacatta cgtcctagat gatagattga acggcggttt ttcaaagtgt cagtaaaagt
     4081 tgtcataata aaatttctcc tttgatttgc gttttgcatt tttttaattg attacgaaat
     4141 gaagtatagc accttacaaa aagtaagtaa acagatatgc tcacaaaaaa taagcgaagt
     4201 tcaaaaaaca attttaataa gaaaaatcgt tatgtaagga ttttcttagt tatcgctttc
     4261 attgttgtgt tttaggaatt tttgcttatt
//
LOCUS       DADVXM010000123         4148 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.130, whole genome shotgun sequence.
ACCESSION   DADVXM010000123 DADVXM010000000
VERSION     DADVXM010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.130"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..614)
                     /locus_tag="KB927_002531"
     CDS             complement(<1..614)
                     /locus_tag="KB927_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841409.1"
                     /translation="MTETKFIQDPWSKMTTRNGLRGDEAISALQKSIRRGKEKEACEF
                     AYEMYITSPQFEEKLWRRLLAISVEDVGMGNPMAAIMINNLNAMRKEFQYNESDRAMY
                     FFHAIRYLCQSEKDRSSDLLKNIVIKSFAMGYIPEIPDIALDKHTVRGQAMGRGSEHF
                     LHEASKVIPQAKVDNDYKEQYEKIIETYDPDHVVPSTFSFNPWQV"
     gene            655..1347
                     /locus_tag="KB927_002532"
     CDS             655..1347
                     /locus_tag="KB927_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6841410.1"
                     /translation="MDVEMLIDKYQLNDSEAEVLRFMKKNRQSLKNIGIRDVAKASYV
                     STATIINMAKKIGYSGYSELVFALGNSQSDITMPSTFSNEEKEAFIHLMSAYRDKRIM
                     ILGSGFSQNLANYFSESLNLYGFRATANSHLEFLRQQVQQDILLFIISNSGDTVRLAE
                     LAKIANDHFIDVIAFVGQKNSKIGTLATLTISTETYIPQKISDYQPNLFFGTTLNQFE
                     LLLSAALKAIYK"
     gene            1907..2590
                     /locus_tag="KB927_002533"
     CDS             1907..2590
                     /locus_tag="KB927_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HBB6841411.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKRFDEPKVVVTDKAPSITSAFKKLKEYGGFYQGTEHRTI
                     KYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTE
                     IKVLLGIPA"
     gene            2615..3028
                     /locus_tag="KB927_002534"
                     /pseudo
     CDS             2615..3028
                     /locus_tag="KB927_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
     gene            3035..4066
                     /locus_tag="KB927_002535"
     CDS             3035..4066
                     /locus_tag="KB927_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6841412.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
BASE COUNT         1258 a          747 c          878 g         1265 t
ORIGIN      
        1 acttgccaag gattaaatga aaacgtactt ggcacgacgt gatctggatc ataggtctcg
       61 atgatttttt cgtattgttc cttgtagtca ttatcaactt ttgcttgggg gatcacttta
      121 cttgcttcat gcaaaaagtg ttctgaacca cgccccattg cctgtccccg aacagtatgt
      181 ttatccaacg caatatcagg aatttctgga atatatccca tagcgaaact cttgataaca
      241 atgttcttaa gtaaatccga tgaacgatct ttttcagatt ggcataggta acgaatcgcg
      301 tggaaaaaat acatcgcacg atcggattca ttgtattgga attctttgcg catggcgttt
      361 aagttattga tcatgatggc ggccatagga ttgcccatgc ccacatcctc aacactgatc
      421 gccaatagcc ttctccagag tttctcttca aattgtggtg aggtgatata catttcataa
      481 gcaaattcac atgcttcttt ttcttttcct cgacgaatcg atttctgtaa tgctgagata
      541 gcttcatctc cacgtaagcc gttacgggta gtcatttttg accacggatc ttgaataaat
      601 ttcgtttctg tcataatata atactcctat tagataaaat ttgaggtgaa tcttatggat
      661 gttgaaatgc ttatagataa ataccaactg aatgactcag aagctgaagt cttacgattt
      721 atgaaaaaaa atcgtcagtc tttaaaaaat attgggattc gtgacgttgc caaagcatcg
      781 tatgtttcta ctgcaacgat tatcaatatg gcgaagaaaa ttggatattc cggttatagt
      841 gagttggtat ttgctctagg aaacagccaa tctgacatta cgatgccaag cacattctcc
      901 aatgaggaga aggaagcatt catacattta atgtctgcgt atcgcgataa acggattatg
      961 attcttggct caggtttttc gcaaaatcta gccaattatt tttcggaatc tcttaatcta
     1021 tatggatttc gtgcgacggc caatagtcat ttagaatttc ttagacagca agtgcaacaa
     1081 gatattctgc tttttattat ttccaattct ggtgatacag ttcgattagc cgaattagct
     1141 aaaattgcga acgatcactt tatcgatgtg atcgcatttg ttgggcaaaa aaattcaaaa
     1201 atcggtacgc tggcaacatt aaccattagc acggaaacct atattccaca aaaaatatct
     1261 gattaccaac caaatctttt ctttggcacg acactgaatc aatttgagct tttgttgagc
     1321 gcggcgctga aggctattta taaatagaag aacgctgtgg ccactgtttc ttcaaaatct
     1381 agtataaaga atcttcttta gaatgtaatt gtttcctgtg tgttctgaac atgtttagga
     1441 atttccaaac ttgtttagaa aactttctca ttccctccgc tgtagaattg aactcacata
     1501 aaaaacatct aaaccaaaat atctacaagc ttggaaagga taataggttg ttattaaaaa
     1561 taatttttat tcctgaacct gaataattca tagctttaat tctttggcac attttattga
     1621 aatatgtatc actaatatcc ctatcaactg attttgacta aaaagttact tcaaacattc
     1681 actgttcaaa aatattgagg aataaatttt gggtgtaagg cattttgagc atacttctcc
     1741 ctggataact tcccagtaaa aaaatcgtta gattgttgga ttagatccat tgactgcctc
     1801 gcctcaggcg agcaaagacc ctgtagaatt caggttctgt tgcaaagttt taaatctact
     1861 atcaaataag gtagaataat agaaaaagat agcaggagga atgacgatga atcattttaa
     1921 aggaaagcaa tttcagcagg atgtgattat tgtagccgtg ggctactatc ttcgttataa
     1981 ccttagctat cgtgaagttc aagaaatctt atatgatcgt ggcattaacg tttctcatac
     2041 aacaatttat cgttgggtgc aagaatatgg caaactactt tatcaaattt ggaaaaagaa
     2101 aaataaaaaa tccttttatt catggaaaat ggatgaaacg tacatcaaaa ttaaaggaaa
     2161 atggcattat ttgtatcgag ccatcgatgc agatggttta accttggata tttggttacg
     2221 taaaaaacgg gacacacaag cagcgtatgc ttttcttaag cggttagtga agcggtttga
     2281 tgaaccgaag gttgtagtca cagataaagc cccctctatt acaagtgcct ttaagaaact
     2341 aaaagaatac ggcggctttt atcaagggac agaacatcgt accattaaat acctgaataa
     2401 tttgattgaa caagaccatc gcccagtaaa gagacgcaat aaattctatc gaagtttacg
     2461 cactgcctct accacgatta aaggcatgga agccatccga ggattatata agaaaacccg
     2521 aaaagaaggc actctcttcg ggttttcggt ctgtactgaa atcaaggtat tattgggaat
     2581 cccagcttaa atcatagata ccgtaaggga ttttattctt tatttaaaac tttgcaacag
     2641 aacccgctta attaatctga aggaattagt ggatgcagca gaaaccttgg gcgccccgat
     2701 gtctacgatt attatccagg tgctgtttcc aaacatccgt atcggtgtga ccctagtttc
     2761 tctgatgatt ttttcttcgg tttttgggga gtacatgctg acgaacctgt tgattggcgg
     2821 tcgatttcag acggtacgca tctatatgct gcggcggatg aacgaaaacg gccatttggc
     2881 tagcgctgtg atggttttgt atttgctgtt tatggtggga attgctttaa ctacctttat
     2941 gctgacttat cgacaaaagc aacagctgtc ccttaagcag acgagggaag agaagcagtc
     3001 gaaaaagaag cccttaaagg agttgtgacg gaaaatgttt ttagaaatac atgatctcaa
     3061 tctgtttttt gatgaaaaac agattttagc tattgatgaa attcagattg aaaagggtga
     3121 gctggttact ttactaggtc ccagcgggtg cggaaagtct acgttgctgc gctgtatcac
     3181 gggattggaa caaccaaaga gcggtgagat tgtgctggac aatgagaata ttgccgataa
     3241 gcctacgaag gatcgcaata tcggctttgt ttttcaacag tatgcattgt ttccaactat
     3301 gactgttttt gaaaatgtag cctttggttt gaaggtaaag aagctgagtc ctgaggtgat
     3361 tcaggaaaag gtttttgaga tgctatcatt ggtggatatg acggagcagg cagataaaaa
     3421 tgtccagttt ctttctggcg gtcaacgaca acgggtggca ctggctcgct cattggtcac
     3481 tgaaccgaaa gtcctgctgc tggatgagcc attaagtgct ttggatgccc gaattagaaa
     3541 acagctgcag cgggatttgc gcgctatcca gcaatcgcta gggatgacga tgatttttgt
     3601 gactcatgac caagaagagg cgatgcgaat cagtgatcgg atttttgtga tggaagctgg
     3661 gcgggtggct caggtttcca cctcgaagga attgtatcag aatcctcaga gccgatttgt
     3721 tgcggaattt atcggcaact ataatcgttt cgaatggtat gagctgaatc agtataccca
     3781 cgagttttcc gctaagggca atcgctgcat ttattattta agaccggagc tgattcaatt
     3841 tgaaccggtt cctcaggggg ttaagattcc ggttctatgg aaggaatcat ttattttagg
     3901 caacattcaa cggtatgttt ttcaaacgct ggagggcaaa gaaattttag tggatcggtt
     3961 gaacgatcgg gaagagaaaa ttagcgatgc cttatacatt cagctgaaag atattctagc
     4021 aatccctgtg gaaattgata ctcagcattt tgcacaacaa agctagtgta tagtcggcaa
     4081 acatttctgg ctctttgtca aataggactg atagagtgat ataagaacat ctaaggtaga
     4141 attgattt
//
LOCUS       DADVXM010000124         4132 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.131, whole genome shotgun sequence.
ACCESSION   DADVXM010000124 DADVXM010000000
VERSION     DADVXM010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.131"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            1024..2037
                     /locus_tag="KB927_002536"
     CDS             1024..2037
                     /locus_tag="KB927_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6841413.1"
                     /translation="MTKKNRVTIRDVAQAAGVSISTVSKALNSLDGVSPETRVEIQNI
                     ASRLNYVPNLMGKQLKSGKTKMIGVYTNRISGPYFNSLIDEIAFESKLHGYGLNVIVS
                     DERDVIMSSLLGNFVDGAIVVEDVLNQKDIETINSNGVATVFINRIVADKKVGSVAFD
                     SFEKGYLAGNYLLNLGHKKIGYVNGVDDIYDNDQRFQGFKAALSKVGLTYNEDFTIAG
                     NFVEEDAYANTLAFIDNQPAELPSAFLAANDMSAVGLIKALTEKNYSVPEDFSVVGFD
                     DVEVLKYFKPSLTTIHNSTKEQGKKAIEHLLEMMGGKSVGRVIEVKGTLMIRETAIEY
                     TGE"
     gene            2044..2394
                     /locus_tag="KB927_002537"
     CDS             2044..2394
                     /locus_tag="KB927_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6841414.1"
                     /translation="MYVGIDVGGTSIKYGLVDSKGNIVAKDTLVASFEKEELLQNLAD
                     IVEKYVSSSPETIEGVGISMPGIVQEDGFLLTAGAIRSCYGINLKEEMEKRTGILTKE
                     VIDSNGANLDWENK"
     gene            2497..3693
                     /locus_tag="KB927_002538"
     CDS             2497..3693
                     /locus_tag="KB927_002538"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HBB6841415.1"
                     /translation="MNKKSAILLLSCGVFLSLATERSFATEENKTNHVSAETALVATS
                     KTTVSKDNPTVFDFPFNGEDNRMHRADGWSNGNMFNTTWRASQVNFEDGKMQLSINKD
                     EENTKIPYISGEYRSNQNFHYGLYEVNMKPIKNDGVVSSFFTYTGPSENNPWDEIDIE
                     FLGKDTTGVQFNYFTNGLGNKEYYHNLGFDASEAFHTYAFEWLPDSITWFVDGEKIYT
                     ATENIPQTPGKIMMNVWPGTGVDSWLNPFDGTVPLKAEYDWIKFTQYKIVEEDVTPKP
                     EEPTTEPTTEPTTEPTTEPTTEPTESSTTGSSTTESSTTNSSGNTTPPATTETTNTTS
                     SSTSQSSKAAGKTTTPKNNSTTSKKDLPATGENTHASYWTAFGGMLILAGLGGALFFK
                     NKNRKA"
     gene            3707..3907
                     /locus_tag="KB927_002539"
     CDS             3707..3907
                     /locus_tag="KB927_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841416.1"
                     /translation="MKAKGVMLVLGCSLLLGLVINRSLAHEKKSKNSGEETESTMVEN
                     KNNAKAQTTVFDFPLGGSVAKF"
     gene            complement(3941..>4132)
                     /locus_tag="KB927_002540"
     CDS             complement(3941..>4132)
                     /locus_tag="KB927_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBB6841417.1"
                     /translation="NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEG
                     TLFGFSVCTEIKVLLGIPA"
BASE COUNT         1400 a          669 c          865 g         1198 t
ORIGIN      
        1 gacaaaaaga aagatctttt gcccatttta tttttataaa atgggtaggt gacgttcgcg
       61 taaagcaaat cgatacaatc caatggtttt ggcgaatcag atttaccatt ctaggcttgt
      121 ttaatacaga catcgattgt tattttgaaa atttatatcc ttattggcaa tgaaatggat
      181 attctccata tcaatagaaa tcttcaagat aattttcgga aatatataag agttaatcaa
      241 ttatgatcat atagtaggta aaaattagga cagccttcaa ttatatggga aaccaatata
      301 atcaagtaat tattcgggta acacaaatac tagagtactc atttcttata actgttttac
      361 acctaaaaat gagcttatcg gaaactttgc aacagaacca gttagctgtt acatttaaga
      421 taatttcaaa atcttgatct attaattaga aagtaggggg taaggtgggg aaaaagaatt
      481 ttgttttatt tttatttgaa acgatggtcc agctttggtc gttattttta tttctgttaa
      541 ttatttataa atactttttt ggaactagtt tttcttttat tacgatcact cggccagaat
      601 tttatttaac gggtttagtt agtcttgttt ctacgatcgt tttatatttt gtccgatcgc
      661 gaaagtaaac aaataaattc ttaaagccaa ctcccttttt gtaaggagtt ggcttcttac
      721 tttcctccgc ccacaagttc atttacctaa cgtgtgaaaa acattcccat aatttctaat
      781 taaataattt atttttatta taaaaacgtt ttccttttct ggtaaaagag caggcgttag
      841 aaatccccaa gctaaaaggt ttttccctga ttcaaacacg aaaaacaaat gtatacgtta
      901 acaaaggcgt taaattagct tttatttttt ataaaaaaag cttgtatcca aaaaaataca
      961 gtgttatact tcaatcgaag taaagaaaaa cgttttcttt aaaaagtaca tgaagtgaat
     1021 aaaatgacaa aaaaaaatcg ggtaacgatt agggatgtgg cacaagcagc tggcgtttca
     1081 atctcgacgg tttccaaagc gttaaacagt ttggatggcg tttcacctga aacccgggtc
     1141 gaaattcaaa atattgccag ccgtttaaac tatgtgccca acttaatggg gaaacagtta
     1201 aagtctggta aaacgaagat gatcggggtt tatacgaatc ggatcagcgg tccttatttt
     1261 aactcactaa ttgatgagat tgcttttgag tctaagttac atggatatgg tttaaatgta
     1321 attgtctctg atgagcggga tgtaattatg agtagtctgt taggtaactt tgttgatggg
     1381 gcgattgtgg tggaggatgt cttaaatcag aaagacattg aaaccattaa ttccaacggc
     1441 gtggcgacgg tttttattaa ccgcatcgta gcggataaaa aagtcggcag tgtggccttt
     1501 gattcgtttg aaaaaggtta tctggcgggg aattatttat taaacttagg tcacaaaaaa
     1561 attggttatg tcaacggggt cgatgatatt tacgataacg accaacgttt tcaaggattt
     1621 aaagcagcct tatcaaaagt cggtttgact tataatgagg actttacgat tgccggtaac
     1681 tttgtagaag aagatgccta tgccaatacg ttagccttta ttgacaatca accagcagag
     1741 ttaccgtcgg cctttttagc ggcgaatgat atgagtgcgg tggggttgat taaagcctta
     1801 actgaaaaaa attattctgt accggaagat tttagtgttg ttggttttga tgatgtggaa
     1861 gttttgaaat atttcaaacc aagcttaaca acgattcata attcaacgaa ggaacaaggt
     1921 aaaaaagcga ttgaacattt attagagatg atgggtggga aatcagtcgg tcgtgtgatt
     1981 gaagttaagg gcacgctgat gattcgagaa acagcaatag aatacacagg agagtgattg
     2041 agtatgtacg ttgggattga cgttgggggc acaagtatta aatacggttt agttgattca
     2101 aaaggaaaca tcgtggccaa agatacgtta gtcgcgagtt tcgaaaaaga ggagctctta
     2161 caaaacttag cggacatcgt ggagaaatat gtaagcagtt cgcctgaaac aatcgaaggt
     2221 gtgggaatca gcatgccagg gattgtccaa gaagatgggt ttttattaac cgctggggcg
     2281 attcgttctt gttacggtat caatctaaaa gaagagatgg aaaaacgtac ggggatttta
     2341 acaaaagaag tgattgattc aaacggggct aacttagact gggaaaataa ataagtcaca
     2401 aagaaacgtc aaacattaac agaaaaataa atgtttggca tttcctttac gaaaaaatga
     2461 aaacgattgc ttaaaaacaa taactggagg gaatttatga ataaaaagag tgcaatttta
     2521 ctattaagct gtggggtatt tttaagtttg gctactgagc ggagcttcgc aacggaggag
     2581 aacaaaacaa atcatgtgag tgctgaaacg gcactagtcg ccaccagtaa aacgacggtt
     2641 tctaaagaca atccaacggt ctttgacttt cctttcaatg gagaagataa ccggatgcat
     2701 cgggccgatg gttggagcaa tgggaatatg tttaatacaa cgtggcgggc ctctcaagta
     2761 aacttcgaag atggtaaaat gcaactttcg attaataaag acgaggaaaa tacaaaaatt
     2821 ccgtatatta gtggggaata ccgttccaat caaaacttcc attacggttt atacgaagtt
     2881 aatatgaaac caattaaaaa tgatggggta gtgtcatctt tctttacgta taccggccca
     2941 agtgaaaata atccctggga tgaaattgat attgagtttt taggtaaaga tacgactggc
     3001 gtacaattta attattttac gaatggcttg ggcaataaag aatactatca taatttaggt
     3061 ttcgacgcct cagaagcatt ccatacgtat gcctttgaat ggttaccaga ttcgatcaca
     3121 tggtttgtcg atggtgaaaa aatctatacc gcgactgaaa atattccgca aacaccaggc
     3181 aaaattatga tgaatgtttg gccgggtact ggagttgact catggttaaa tccctttgat
     3241 ggaacggtac cattaaaagc cgaatacgac tggattaaat ttacgcaata taaaatcgtt
     3301 gaggaagatg tcacgcctaa accagaagaa ccaacgacag aaccaacgac agaaccaaca
     3361 acagaaccaa caacagaacc aacaacagaa ccaacggaat cttcaacaac gggaagttcg
     3421 acaacggaat cttcaacaac taacagtagc ggaaatacga caccaccagc aacaactgaa
     3481 acaactaaca caacctcaag ctcaactagt cagtcgtcca aagccgcagg caaaacaacg
     3541 acgccaaaaa ataatagtac aactagtaaa aaagatttac ctgctacagg agagaataca
     3601 catgctagct attggactgc ttttggcgga atgcttattt tagctggtct aggcggcgcc
     3661 ttattcttta aaaataaaaa ccgtaaagcg taatcggagg ggatttatga aagcgaaagg
     3721 tgttatgcta gtattaggct gtagcttatt gcttggttta gtaattaatc gcagtttggc
     3781 ccatgagaaa aaaagtaaaa atagtggcga ggagacggag agtacgatgg tagaaaataa
     3841 aaataacgct aaagctcaga caactgtctt tgactttcca ctagggggtt ctgttgcaaa
     3901 gttttaaata aagaataaaa tcccttacgg tatctatgat ttaagctggg attcccaata
     3961 ataccttgat ttcagtacag accgaaaacc cgaagagagt gccttctttt cgggttttct
     4021 tatataatcc tcgaatggct tccatgcctt taatcgtggt agaggcagtg cgtaaacttc
     4081 gatagaattt attgcgtctc tttactggac gatggtcttg ttcaatcaaa tt
//
LOCUS       DADVXM010000125         4054 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.132, whole genome shotgun sequence.
ACCESSION   DADVXM010000125 DADVXM010000000
VERSION     DADVXM010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4054
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.132"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            1..691
                     /locus_tag="KB927_002541"
                     /pseudo
     CDS             1..691
                     /locus_tag="KB927_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400714.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1033..1269
                     /locus_tag="KB927_002542"
     CDS             1033..1269
                     /locus_tag="KB927_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBB6841418.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMMD
                     AIVKEESNLDLEIDMYVNQALSEYDSAFKELVDK"
     gene            1266..1679
                     /locus_tag="KB927_002543"
     CDS             1266..1679
                     /locus_tag="KB927_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBB6841419.1"
                     /translation="MIYLNEKDIVKLNVIQIKKYSPQETIGVIDKNALSMAVNQPKQH
                     IFGESLYPDEFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMENQEVV
                     EFVVRIATYQGEFDDLKEATTDILKNNSTKFDTKK"
     gene            2198..3148
                     /locus_tag="KB927_002544"
     CDS             2198..3148
                     /locus_tag="KB927_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBB6841420.1"
                     /translation="MERNSENKMTGRNPKVFISYSWENKENKEWARELADKLLENGID
                     AYIDQYDLSLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAEL
                     LSGKNERKFIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKP
                     ALGDIPRHIKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRV
                     PSQLWKELFVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIE
                     KSNTQEKKILLEEEQKKERENERVRSHKESVQKLADELEF"
     gene            complement(3145..3741)
                     /locus_tag="KB927_002545"
     CDS             complement(3145..3741)
                     /locus_tag="KB927_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6841421.1"
                     /translation="MQQNPSIDQNEQRQIEEMRKFGAEKIFIEKQSGATITHRPIFQE
                     VLDFVRDQDIFIVEAIDRLGRNYDEIIDSVNYLKKKNVRLIITNLPIMAEAIGNPLLD
                     KFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANTKDPQRRLV
                     YRSIVQDQENGVAISKIATDYNVTRQTVYRIKKELTIN"
     gene            3802..>4054
                     /locus_tag="KB927_002546"
     CDS             3802..>4054
                     /locus_tag="KB927_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBB6841422.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKG"
BASE COUNT         1497 a          554 c          707 g         1296 t
ORIGIN      
        1 atttttttat gtgttatttg gttctgaact ccctgtcaaa tttatagagt ttgaatatgg
       61 atcgataaat ataggtaaca aagttattgg aaaaaaatat aggatgtatg tcaggcagaa
      121 tgctaaagtt caatcaagaa agcttagacc ttatgagcta tttccttatg ccacaatagc
      181 cgataattta tcaaaatata ttaataattg gttcgcattt tatgcagatt tagagactat
      241 tatacagaca tatgtaggag acttacaact tacatccttt ttagaaacac agtttctcaa
      301 tgcttgtaga aatgtagaaa tttttcatcg aatatatttg gagaaagaaa agatagaagg
      361 ccctgaaatt gtgtttatga gaaaaaaact catggaaatt gtaacagggg cagaagagcc
      421 cgtcagaaaa tacttttctg aaagaataaa ttatacggga gaagaaacac tctcgaaaag
      481 aataaaagaa agcttaaaag ttgttccgaa ccctattcta aaggaaacta tcttatacag
      541 atctaagtca ttatccgatt ctaaaactag atttgtgaga gcgtgcgtga atacaagaaa
      601 tttcttaaca catggcagtc aggataaaag caaatatcaa cccatttttg aaaaagaaaa
      661 tctatatatg gcaacaaaaa ttttaaatac tattataaga tattttgtac ttgaaaaaat
      721 aaatattgac tcggaaattc ttgaagaaaa gatattagag gatatgaacc gtgaaggagt
      781 ttctgggaac aaattgaact aacaaatata aatctcacat aattgaactt ttcttaaaaa
      841 tttgaacttt cttaatttaa aaagattaaa atatttaata gacttatata ttaataatct
      901 caatgatagt tgataaattt tagatagttc gtcctatatt tgtaaaagat atacttaagc
      961 attgcaatat aaatattaag atattgatta ataaagatat acggtatata cttgttttag
     1021 ggagttgatt atatgaatat taaaaaaagg aaaattagag aggtaggcaa ctcgatagtt
     1081 gtcactttgt caaaagaaag tttattacaa aaaggattga aacccggaga tacaattttt
     1141 attgatgaag acaaaatgat ggatgctatt gtgaaagaag aaagcaattt agatcttgaa
     1201 attgatatgt atgtgaatca agctttatcc gaatatgact cagcatttaa ggaactggtt
     1261 gataaatgat ctatttaaat gaaaaagata tagtaaaatt aaatgttatt caaataaaga
     1321 agtattcacc tcaggaaaca attggtgtta ttgataaaaa tgctttgagt atggccgtaa
     1381 accaacctaa gcagcatatt tttggagaat ccctatatcc tgatgagttt agcaaagcag
     1441 cagttctatt aataaatctg atcaaaaaac atccatttca taatgcaaac aaacgtactg
     1501 catttctagc tgcatatgtt tttctcaagc taaatggtta ctcactaaaa atggaaaatc
     1561 aggaagtcgt ggaatttgta gttaggattg caacgtatca gggtgagttt gatgacttaa
     1621 aagaggcaac aactgatata ctaaaaaata attcaacaaa gtttgataca aaaaaataga
     1681 agcaaactag gagttcagta aattctgaaa tgttagtttg ctttctattt tagtttacat
     1741 aagatacatt atgcgaagtt cattatttta aaagcttaaa taataaactt ttttataata
     1801 ccaatttatt tatgtaaacc aatgacctta atcgcttaag caagcatgtt atgtaatact
     1861 ctactctctc caaaactaat gactatctat tttcaaagaa gctagaatga ttatctgatc
     1921 aaatgataat ttatatttaa ttcctggtct actgctcttc ttttaatcaa ttaatgtcta
     1981 acgtactgta cacgataaag taggaagact tattttcaac ttcggattca tttttttaat
     2041 tcggtgaaaa tcactaaatt aagagtttat ccaagttcat tttagctgag aatacgcttg
     2101 aaaataattt tgatgaattt tcctgaatta aaatttatta acttgttgag tgatataatt
     2161 gtaatgtatt accaaatagt tagcacttag attagtgatg gaaaggaata gtgagaacaa
     2221 gatgactggt agaaatccca aagtatttat atcatattca tgggagaata aggaaaataa
     2281 agaatgggct agagaactag cagacaaatt acttgaaaac ggtattgatg catatataga
     2341 tcagtatgat ttaagtttag gtgatagatt acctcagttt atggagcagc aaatatccga
     2401 ttcagattat gttctaatta tatgtacacc agagtataaa aaaaaggcaa ataatcgtac
     2461 aagtggtgtt gggtatgaag gtcatattat ctcagcagaa ttgctttctg gaaaaaatga
     2521 acgtaaattt atcccaataa ttaaagaagg acgtgcaagc gaagtacttc ctacttttct
     2581 tgctggaaag cttggaattg atttatcaga tagccagcat tatgatgaaa acttagatga
     2641 tttaattaca actatatttg gtgttaagag aaaaccagca ttaggtgata tacctaggca
     2701 tattaaaggc agtcctttac tacctataga acataatgaa aataaagata ttgaaatctt
     2761 aggaattatc actgataaag taactgtacc taaaatggat ggctcaaggg gttctgcatt
     2821 atataaaatt ccatttagat taaatagagt accaagtcag ctttggaaag agttgtttgt
     2881 tagaaattgg aattcaccac cacgatatac aacaatgcat agaccaggaa ttgcttctgt
     2941 tgtagacgat gaaattttac ttaatggaac aactattgag gaagtccggg aatatcatcg
     3001 ggaaacttta aaactttgca ttgaaaaaag taatactcaa gaaaaaaaaa tattgctaga
     3061 ggaggaacaa aaaaaagaga gagagaatga gcgagtcaga tcacataaag aaagtgttca
     3121 gaaattagca gatgaattag agttctagtt gatagtcagt tctttcttaa ttcgatacac
     3181 agtttgtcta gttacattat agtctgttgc tatttttgaa atagcaacac cattctcctg
     3241 gtcctgaacg atgcttctat aaacaaggcg acgttgagga tcttttgtgt tcgcactgta
     3301 taacttagga cgtcctttat agacgccgtt tgctttagca atctttatcc cttgtgcctg
     3361 gcgtcgtttt gattcagtac gctcttgttc agcaatcatg gccaagattt gaatgattag
     3421 gtctttgata aatttatcca ggagaggatt tccgattgct tcagccatga tcggtaaatt
     3481 agtgataata agtcgcacat ttttcttctt tagataattt actgaatcga taatctcgtc
     3541 ataattacgt ccaagtcgat cgatagcctc tacaataaaa atatcttggt ctctaacaaa
     3601 atctagaact tcctgaaaaa tcggtcgatg agtaatagtc gctccagatt gtttctcgat
     3661 gaaaattttt tcagcaccaa attttctcat ttcctcgatt tgacgttgtt cattttgatc
     3721 gatcgatggg ttctgttgca aagttttcca aaaaatctat tttagtgtaa aattgagaaa
     3781 aaagacagag aggacagagt aatgaatcat tttaaaggca aacaattcaa aaaagacgtc
     3841 attattgtcg ctgttggtta ctacctgcgt tacaatctaa gctatcgtga agttcaggaa
     3901 ttgttatatg atcgtggaat aaatgtttgt catactacga tttatcgttg ggtacaagag
     3961 tacagcaaag tcctctatta tctttggaag aagaaaaata gacaatcctt ctattcatgg
     4021 aaaatggacg aaacctatat caaaattaag ggac
//
LOCUS       DADVXM010000126         3856 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.133, whole genome shotgun sequence.
ACCESSION   DADVXM010000126 DADVXM010000000
VERSION     DADVXM010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.133"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..1824
                     /locus_tag="KB927_002547"
     CDS             <1..1824
                     /locus_tag="KB927_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009321393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841423.1"
                     /translation="EILDKFYTIFTEEYSQNKLELINNKLTSTDKSVYDLYCYPLNEF
                     VQKQPISNSILLQYHKLQKEDFLDSVGVFYTDLQANEIREIESQLAVTISVFENEAIP
                     YSMILELYLLNFVILFVVLQIIYCIYTSDSLKKKGIKKSMGFSAMHILKEQINNIVKY
                     FIVICSVLFILLNLYYALTNRFNISYLTISIFFFAIILVINILCVLITSFLIKFVSLE
                     AMIKNKTLNSGTNLIVQTIKIVFSVIITITTISLLNQGNEFKQSQQDILDYKYLDGYF
                     TANGFNSLEYEYALENPEQFEEYSNSMLELYNNHHALLCDYAGSSEAQGEFSKSRPYY
                     IQQTIIANRNYISEFSNIQVNGKSLNEDIYDTPTILVSRKYKSDETFIKEHITQEYFR
                     LMNYNQFYGIPEKERHINEFNIVYVDDNSTIKVNTENGFSDMSEPIIIIDTGNFAGLY
                     YLDSLNTRNLFFQMDSREEFSSLLAEYGLKQLVTAGTLLTPYLMQLENVTFVLKTLTM
                     FAIVFIISLLFILYISNYVDIFVNRKKYATKEIMGFSHFKTLKNRYIFWGIELIASCI
                     LTAINYNFACLFAIILIDYIFCELLYRIYILNALYEIEKGA"
     gene            1827..2477
                     /locus_tag="KB927_002548"
     CDS             1827..2477
                     /locus_tag="KB927_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6841424.1"
                     /translation="MSLITLKNIKKVYGKNQILFENLSLEIEKGEFVGLVGKSGAGKT
                     TLLNIIGLITDISEGIITIDGQQKLSVNSRNAMLLRRYTIGYLFQNYGLIEDESVLWN
                     LKLALEYKKMKKEDKLKVINEYLKQFNLSDMLNKKIYQLSGGEQQRIAIIKLILQGSQ
                     IILADEPTSGLDKENEQVVMKLLKELNEKGITIIMVTHNMDLRNYFSRVINVETFR"
     gene            complement(2937..3539)
                     /locus_tag="KB927_002549"
                     /pseudo
     CDS             complement(2937..3539)
                     /locus_tag="KB927_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3665..>3856
                     /locus_tag="KB927_002550"
     CDS             3665..>3856
                     /locus_tag="KB927_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6841425.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPTPRA
                     CRNCGSTVVDGNGKVIVVKN"
BASE COUNT         1375 a          522 c          645 g         1314 t
ORIGIN      
        1 gaaattcttg ataaatttta tacgatattt acagaagaat attcccaaaa taaattagag
       61 cttatcaata ataaacttac ttctacggat aaatctgtct atgatttata ttgttatccg
      121 ctaaatgaat ttgtgcaaaa acagcctata tcaaattcta ttctgttgca gtatcataaa
      181 ttgcaaaagg aagatttttt ggatagtgtc ggggtattct atacggattt gcaagccaat
      241 gaaatacgtg aaatagaatc tcaactggct gtaacaatta gtgtttttga aaatgaagct
      301 atcccgtata gtatgatatt agagttgtat cttcttaatt ttgtaatttt gtttgttgta
      361 cttcaaataa tatattgtat ttatacatct gatagtttga aaaaaaaagg tattaaaaaa
      421 agtatgggct tttctgctat gcatatttta aaggagcaaa tcaacaatat agtaaaatat
      481 tttattgtga tatgttcggt gttatttatc ctgctgaatt tgtattacgc attaacaaat
      541 cgttttaata tttcttattt aacaataagt atatttttct ttgcgattat tttggttata
      601 aacatacttt gcgttttaat taccagcttt ttaattaagt ttgtttcttt ggaggcaatg
      661 attaaaaata agactttaaa tagcggtaca aatcttatag ttcagactat aaaaatagtt
      721 ttttcagtaa taatcacaat taccactatt tcattattga atcaaggaaa tgaatttaaa
      781 caaagccaac aggatatttt agattataaa tatctggacg gatattttac ggctaatggt
      841 tttaattctt tagaatatga atatgcatta gaaaatccag aacaatttga agaatattct
      901 aattcgatgt tagaactgta taataatcat catgccttgt tatgtgatta tgctggtagc
      961 agtgaagcac aaggggaatt tagtaaatct cgtccatatt atatacagca aacaataatt
     1021 gcaaatagaa actatattag tgagttttca aatatccaag ttaatggaaa atcattaaat
     1081 gaggatatat atgatacgcc aacaatatta gtttcccgta aatataaaag tgatgaaact
     1141 tttattaaag agcatataac tcaagagtat tttcgactga tgaactacaa tcaattttat
     1201 gggatacctg agaaggaaag gcatatcaac gaatttaata ttgtgtatgt cgatgataat
     1261 tctactataa aagttaatac agaaaatggc ttttcagata tgtcagaacc tattatcatt
     1321 attgatacag gcaattttgc aggtctttac tatttggatt ctttaaatac aagaaattta
     1381 tttttccaaa tggattcaag agaagaattt tcttctttat tagcagagta tggtttaaaa
     1441 caattagtta cggcaggaac attacttaca ccatacttaa tgcaactgga aaatgtgacc
     1501 tttgtcctta aaacactcac aatgtttgcg attgtcttta taatatcatt actgtttatc
     1561 ttgtatattt caaattatgt agatattttt gtgaatcgaa aaaaatatgc aactaaagag
     1621 attatgggat tctctcattt taaaacatta aaaaatcgtt atatattttg gggaatagag
     1681 ttgattgcat catgtatatt gactgctata aattacaatt ttgcttgtct ttttgcaatt
     1741 atacttattg actatatatt ctgtgaatta ctttatagaa tttatatctt aaacgctttg
     1801 tatgaaatag aaaagggggc ataagtatgt cattgattac attaaagaac ataaaaaaag
     1861 tatatggtaa aaatcaaatt ttattcgaga atttgtcgtt agaaatagaa aagggtgaat
     1921 ttgttggtct tgtaggtaaa agtggtgcag gtaagacaac tcttttaaat ataattggat
     1981 tgattacaga catatcagag ggaataatta ctattgacgg tcaacaaaaa ttatcagtaa
     2041 acagtagaaa tgcaatgctt ttaagacgat atacgatagg ctatctattt caaaactatg
     2101 gacttataga agatgaaagc gtattatgga atttaaaatt agctcttgaa tataaaaaaa
     2161 tgaaaaagga agataaactg aaagtaatca acgaatattt aaaacaattt aatttgagcg
     2221 atatgctcaa taaaaaaata tatcagttaa gcggtggaga gcaacagcgg attgcaatta
     2281 tcaaattaat tttacaagga agtcaaatta tactagccga tgaaccaact tctggacttg
     2341 ataaagaaaa tgaacaggta gtgatgaaac ttctgaaaga attgaatgaa aagggcatta
     2401 ctataattat ggtaactcat aacatggatt tgcgtaacta tttttccaga gttataaatg
     2461 tagaaacttt tagatagttt attaaaggga gatatacttt tttgtgcaat ctcccttgtt
     2521 ctttttctgt catatcaaga ctcgttcaat aatggtaaat tcgtggtaaa atagctactt
     2581 ttttagttga tgaatagccc ttaaatactg tatttatgcg gataatcgga ttttttatac
     2641 caagtttgga tatatcaaca aatcatttga taattatgat cttggtttta taattaattt
     2701 aaaaaaaata aaaactatcg atgacttact cacaaataat ttagttctca aaaaagcgta
     2761 ctgtgataca ttctaatgac gagagcgtct ttaccggaaa aatcaatctt ttagattcaa
     2821 aaaaactagt actttctata atagattacg aaagcatcac aaagacgaac aaaaaaaaca
     2881 ataaatatag atgcagactg tagacatcat ccataaaatg gactttgtct acagtctgaa
     2941 acgagatctt tcttcttacg tgaaggaaga atatccagta atttcccagt atcgccatcc
     3001 atacaagaaa aagaataggg accgacttga tttttcaatg aacgaaattc atccaccaat
     3061 gaacagcgag gcaaccaatt ccttttcacg tttgtcatgg ggagcagaga agcgagtgtt
     3121 cgcgaaacgg ttgaccaaga aacgccgcaa tgtttagaaa tcgtcgtcat tgcttgtttt
     3181 tcagtcaatt cctccaatat tttataatgt acttgtttgg cgataaaaca gtttttttca
     3241 acaatgtagg tattcgccgt aaaataggtg tgacagccac gacagaggta ccgttgcttt
     3301 gccaaagcaa gataagtccg ttgattcgca cacttattga gaaggaccag cgattttttc
     3361 tttccgctct taacgatcag cccatgttgc ttcacctgtt tacactgagg acagcgctga
     3421 atcgttttaa tgagcgtggc agaaacaacg atactgttga ttgaatgtat ttttttcttc
     3481 tcgacatgag tgatttgaat gtttttatct ttgattccta gtaatagtgg ctctataatt
     3541 tatgggactg atgaatcaga attgattctt cagccccatt tttattttag gtattaaaaa
     3601 acatatcgtt ctctagtatg attaaatcac gacaaaataa acaactgaga ggacgatatg
     3661 ctatatgaat gattctatca aaaaaatgct gcgattaata gagaaagatt tgatgattac
     3721 agaggtctct tacgagacct ttcagaagaa aaagacgttg atcgtcgatg ctgttttctc
     3781 acctactcct cgtgcttgta gaaattgtgg ttctactgtg gtagatggaa acgggaaagt
     3841 aattgtagtg aaaaat
//
LOCUS       DADVXM010000127         3854 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.134, whole genome shotgun sequence.
ACCESSION   DADVXM010000127 DADVXM010000000
VERSION     DADVXM010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.134"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..345
                     /locus_tag="KB927_002551"
     CDS             <1..345
                     /locus_tag="KB927_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841426.1"
                     /translation="IIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFLMSLKP
                     PKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYIGYFPN
                     KNNNFYFYRNKL"
     gene            complement(471..1148)
                     /gene="nth"
                     /locus_tag="KB927_002552"
     CDS             complement(471..1148)
                     /gene="nth"
                     /locus_tag="KB927_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBB6841427.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(1155..1853)
                     /locus_tag="KB927_002553"
     CDS             complement(1155..1853)
                     /locus_tag="KB927_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBB6841428.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2121..3305
                     /locus_tag="KB927_002554"
     CDS             2121..3305
                     /locus_tag="KB927_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBB6841429.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3311..3754)
                     /locus_tag="KB927_002555"
     CDS             complement(3311..3754)
                     /locus_tag="KB927_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6841430.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
BASE COUNT         1003 a          760 c          636 g         1455 t
ORIGIN      
        1 attatttttt ctgtactttt aagcactact cttaaaggaa aatttatgga aagaagctct
       61 catgcaatga ttctcacttt tttatggttg ttgttcacca gaatctatat ttttctgatg
      121 agcctgaaac cgcccaaatc cattagttta tgtttagtta taaatggtat ttttttatta
      181 tcacttatca tttttattac acctttagat agatacgtca cttatttata taatcctttg
      241 gaatactgga cttattttat aggtatattg gaaggcatta ttttctacat cgggtatttt
      301 cccaataaaa ataacaactt ttatttttat cgcaataaat tgtaataagt taccatccta
      361 gctactgagt atgtacattt actttttcat gcaaaaaaga taaacgaaac agcttttctc
      421 cataataaca agataattca tacatttatt tgcaattaaa gaaaccacgt ctacaggcgt
      481 ggtttctttt ttagcgcctt ttcttttaga cgcatccgat ttttcccatc ttgacatatt
      541 gatagcaaag gacatacctc gcacttggga tttcttgccg tgcaatgata tctaccaaaa
      601 aaaatcagtg tatgatgtgt ctttacccat aattcttgtg gtactttccg catcagtgtt
      661 tcttctactt ccatgaccgt agcatctagt ttgcagatcc tcaggcgttt tgagacacgt
      721 tccacgtggg tatctactgc gattgctggt atcccgaatg catcccccaa tacgacattt
      781 gctgtctttc tgcctacacc aggaagagac atcaattctt ctcttgacgt tggcacttgc
      841 ccatcgaaac gttcaatcag ctgctgtgca cacgctttga tgttttttgc tttatttcga
      901 tacaaaccaa tcgtttttat tttaagaatg atttcatcga ttgaagcttc tgctaacgca
      961 tcgggtgtcg gaaaagaggc aaacaaatct ggcgttgctt tattcactga tacatctgtc
     1021 gcctgggcac ttaagatcac tgcaatcaat aactcaaatg gattattgtg cttgagttct
     1081 ccatgtgctt cgggaaacat tccatacatc gtttctagag cttccattgt tttttgtttg
     1141 cttaacatat tccgctactc ctccaaccaa tttttcagtg agactttcgg caattcttct
     1201 tgttgagctg actgttctac ttctctttga agaagctgct gttttcttcg tttttggtct
     1261 tcttccactt gttgttttgt acgtagattt tttctttccc acgatagcaa aatgcggtca
     1321 acgtaattaa aactataagc ctgatttaat acggcttccc gcagtgctag cttcaaaatt
     1381 tccggctgat aatggtcttc ttctagccat tgtccgatcc gctggaactc gatcgaagaa
     1441 agcgggcgtc caaattcttg ttcaaataat tgatacactg actggatttc tttttcttgt
     1501 gttttttctt cgtatttttt ttcttgtgtt tttaaatact cacctaatag atcatagatg
     1561 gggtaaagat tatatcgatc tgctttttta ccgttgacaa tcgtcgtttc tatcttgata
     1621 aatccatttg ttacgagacg atccagtatt tgaaaaatct gatcttgttt gattcccata
     1681 tccatagcaa tcatctgcaa atcagggaaa gtatctcctt caagctgtgc catatgcaac
     1741 tgtagaacaa ataaaaattc ttcagattgt agaccgatcc tatgataatt tttaagtaaa
     1801 agattagata tgactgtttg tccagcgctt aagtaatttt ctaaattcaa catgatttct
     1861 cctccgctca atcacagtat acgtaaaaaa aacatgggaa gcaagaacag gtttcttttc
     1921 tatttacttc actgatcggt cagatttaca atgtcgtcta cttgattttt gtttgttcat
     1981 gtttttgatg cgtatcttca cttttcggaa taaataaatt aagtagattt cgctgttcct
     2041 tagaatgttg acaaggaaac aaaattacta tacactattt ttgtttccaa gttaacatta
     2101 ttgcataaag gagtttttac atgtacagtt tcacaaataa acattctaaa gtttttggat
     2161 acgtctctgt cttattcact ggattaggat ttactatcgt cagtcctgta cttccgtttt
     2221 taacgctgcc ttattctcac tccatacatc agcaagcttt ctatatcact ttgctcatgt
     2281 ctgtttatgc tctagctgcc ttcttatctg cccccattct cggtagctta agtgatcatt
     2341 ttgggcgtca tccgatcctt attatcagtt tattaggatc aagtatcgga tatttgcttt
     2401 ttggtttagg aaattcgata tggatgttgt tccttggtcg tatcattgaa ggattgacgg
     2461 caggagaaat ctccacctta tatgcttact ttgccgacat cacggaacct aatgaaagaa
     2521 ccaaagtttt tggatggatg ggtgctttag tcggtatagg aacaacgctg ggtcctatta
     2581 tagggggtct attagctgag ttggggaatt ctgttcctat atttattgga gcactcttta
     2641 ctttcttaaa tgccgtttat ggctacacat ttatgctaga aagccttcca ataaaaaaac
     2701 gttcagtaga tttaagtttc tcccatgtaa gaccttttca ccaattacaa caattattca
     2761 agatttcatc cgttattcct ttattgacag caggttttgc tgtttggttg gcagctggct
     2821 ctcttcaatc tatcttttct caattttcga ttgacgcctt tcagtggaag gctgggttgg
     2881 ttggtttaag cttctctttg attggaatct tggatactgt ctcgcaattg ttcattatgc
     2941 ctcgattgct caaaaaattt tcagaacagc agatcacaag aatagggatg ttcagtgaaa
     3001 tcctcgccta tctattcatc acattatctg gaattcttct actgccgatt ttgtttttat
     3061 ttgggattat ctgttatggt ttcggtgatt ctatttttac tcctgtattc aatggccaac
     3121 tatccaattc tgtctcagat aaccagcaag gtcttgtaat gggcggtacc caaagtatac
     3181 aatctctatc gcgcgtcatc ggcccgctaa tcgcaggaca gctttatgct gcagcaccat
     3241 ttcttccgac ggtattcgga tttttgctta tgatttttgc ctattatcac tacaataaaa
     3301 aatagtagct tcatttgcta cttcgtataa attctctgta tcgaccgata aaacgaaata
     3361 ctgtgtcaaa ttcttctttt gacatatttt caaatacagt agcatctcgc tgtacccatt
     3421 tttgatggag ttgctcgtgt ctattcctta ttttttgtcc gattggcgtc aattgaaaat
     3481 agatttcttt tttattctct tcgctttgat aagtgtttat gatccctcta gctatcagtt
     3541 tttttgttag cttactgatg gctcctctag tcatgtaact agcattcgct aattttgtca
     3601 cgttaggatc agggattttc ccgatatgtt caatcacttc tagttcattt agagtaaatc
     3661 ctgcaaattc tttttccatt tctggtttat tacgatgaat aatctcatta gctaaatcca
     3721 gatattcttc tattagcagt tgtcttttat ccatttctac accttctttt tctttcatta
     3781 tattgttttt ttgtttccta ttcaacaaag ataaaaatat tttgtaggaa aacccaatct
     3841 gaaaccaaga aaaa
//
LOCUS       DADVXM010000128         3781 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.135, whole genome shotgun sequence.
ACCESSION   DADVXM010000128 DADVXM010000000
VERSION     DADVXM010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.135"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            4..1305
                     /locus_tag="KB927_002556"
     CDS             4..1305
                     /locus_tag="KB927_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6841431.1"
                     /translation="MENSAFIMKLNDILSPIAAKIGNQRHLKAISSGMMFGLPFIVIG
                     SFFLIFANPPINIDKYNPDTANIFMKFMASWKDFAVANYDLITAPYNLTMGIIGFISV
                     FGIAFSLANEYKINPSMNGMVASVIYLMVCTPVEEGAINLNFLGTNGLFVAIIIGLLV
                     VEINRLFEVKNIKLKLPDTVPPMVATFINMLVPLLTNIFIFYGINLIFLAATNKIFPE
                     AVMEVLTPATNIAGSLGGFLLIVTLGNILWLFGINGSSIIFPIVFTLGMAQTGLNAEQ
                     LANGETMTHLMNLQMFRISVLGGAGGTLGLVLLMMRSKVPEYRTIGKLSLVPGICSIN
                     EPVIFGLPIVFNPILAIPFLITPIISLLLTYFAQQLGWIGIGFIVDPSFTPFFAQAYL
                     SSMDWRNILFCLLLIVISIFIYYPFFKVMESNKTKLVDEKL"
     gene            1704..2894
                     /locus_tag="KB927_002557"
     CDS             1704..2894
                     /locus_tag="KB927_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBB6841432.1"
                     /translation="MNYFTTSLMKNLFSNDNNLPAFEQAVTELFRSELEKSLNEILAY
                     ELTDFLDYEPYARTNNENSRNGSYQRKFDTKYGTITLNIPRDRMGEFFTSLLPKYRRR
                     DLFTETTILDLFEEGMSHSEICSMIQKLCGARYSKQTISNITDKALECVDSFKNRILN
                     KEYAVVYLDGTSMPLRRDTVSREMVHIALGITVEGTKEILGYMIAPNESAEIWEELLK
                     DLKSRGVERISLFCTDGLSGMENVIQDIFPGSKIQRCLVHIQRNICAKVRVSDRKEVA
                     NEFKEVYRSKSKEEALTSLKKFIDRWKHKYPSMVKSLSNNDYLFTFYDYPESVRHTIY
                     STNLIEGNNKQLKRSFKKKEQFPTEKSEEKYLVIQFNRYNEKNMNHVHRGFGQTTRED
                     WFKS"
     gene            3063..3485
                     /locus_tag="KB927_002558"
     CDS             3063..3485
                     /locus_tag="KB927_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841433.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            3495..3698
                     /locus_tag="KB927_002559"
     CDS             3495..3698
                     /locus_tag="KB927_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841434.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
BASE COUNT         1305 a          649 c          652 g         1175 t
ORIGIN      
        1 tatatggaaa attctgcgtt tatcatgaaa ctgaatgaca tacttagccc catcgcagcc
       61 aagataggta atcagcgcca cctaaaagct atatccagcg gtatgatgtt tggcctaccc
      121 tttattgtta tcggttcttt ttttctgatt tttgcaaatc cacccatcaa tattgataaa
      181 tacaatccag atacagctaa tattttcatg aaatttatgg ccagctggaa agattttgcc
      241 gtagcaaatt atgatctcat cacagcccct tataatttga caatgggaat catcggattc
      301 attagtgttt ttggcattgc attttccctt gccaatgaat acaaaattaa tccttccatg
      361 aatggcatgg ttgcatctgt catttatcta atggtttgta caccagtgga agaaggtgcc
      421 atcaatctta atttccttgg gacaaacgga ttgttcgtcg caattatcat cggcttgcta
      481 gtagtggaaa tcaaccgact atttgaagta aaaaatatta agttgaaact cccagataca
      541 gttccaccca tggtagcaac ctttatcaat atgctcgttc cactgctgac aaatatattc
      601 atcttttatg gcatcaatct gattttcttg gcagcaacaa acaaaatctt ccctgaagcg
      661 gtgatggaag tcctgactcc agcaacgaac atcgctggca gtctaggtgg tttcttattg
      721 atcgtgactt tgggtaacat cctatggcta tttggtatca atggctcgtc aattattttc
      781 cctatcgtct ttacattggg aatggctcaa actggtttga atgctgaaca actggcaaat
      841 ggtgaaacca tgacacactt aatgaactta caaatgttcc gtatttctgt acttggtgga
      901 gccggtggta ctttgggttt ggttttattg atgatgcgaa gcaaagtacc cgaatatcgc
      961 acaattggaa aattgtcatt ggttcctgga atctgttcca tcaacgaacc agtgattttc
     1021 ggattaccta tcgtttttaa ccctattttg gcaattccat ttttgattac gcccatcatt
     1081 tcattattgc tgacctactt tgctcagcaa ctaggatgga ttgggattgg atttatcgtc
     1141 gatccttcct tcacaccttt ttttgcacaa gcttatcttt caagtatgga ctggcgcaat
     1201 attctctttt gcctactgtt gatcgtcatc agcatcttca tctactatcc attttttaaa
     1261 gtcatggaga gcaataaaac aaaattagta gatgaaaaac tatagtcgtc attcttaacc
     1321 ttgtaacgaa aatatggttc tatactattt agtgttgatg ggaaatctta gggtttccca
     1381 tcaacctatt ttttataaaa aagtatactc tggtgtccca caacaaataa aggaagcgcc
     1441 cttgttcaaa aggctacttc ctttattttt attttgcttt aaattttgag tcatcattta
     1501 taagcgaacg taagagataa tagacaccta aaaatagaaa gaaaaataaa ggtaatacac
     1561 gtagtaaaac aaatggagtt tcaaaaataa atggatagca taaaatatct tgtgtaaatt
     1621 cgtttttcta gaaatgtaga aaaaaaggta tatccttagt aaaattagtt cgaccaaaaa
     1681 caatttacga aaggaatata cccatgaact attttactac atctttaatg aaaaacctat
     1741 tttctaatga caacaatctt ccagcttttg aacaggctgt aaccgaactg tttcgttcag
     1801 agttggagaa atctctcaat gaaatactcg catatgagtt gacggatttt cttgattatg
     1861 aaccatacgc tagaaccaat aacgaaaatt ctagaaatgg ttcctatcaa agaaagtttg
     1921 atacaaaata tggaactatt acactcaata ttccaagaga tagaatggga gaatttttca
     1981 cttctcttct gcctaaatac agaagacgag atctatttac cgaaacaacg attttggatt
     2041 tatttgaaga aggaatgagc cattcagaaa tttgttccat gatccaaaaa ttatgtggag
     2101 ctcgctattc taaacagacc atatctaata ttacggacaa agctctggaa tgtgtagatt
     2161 ccttcaaaaa cagaatattg aacaaagagt atgccgttgt atatcttgat ggaacatcca
     2221 tgcctttacg ccgtgatact gtatccaggg aaatggtcca tatagcacta ggaatcacag
     2281 tagaaggtac aaaagaaatt cttggctata tgattgcacc aaacgagtcc gctgagatat
     2341 gggaagaact tctgaaagac cttaaatcaa gaggggttga acgtatttct ttattttgta
     2401 cagacggatt gtctgggatg gaaaatgtaa tacaggacat tttcccgggc tctaaaattc
     2461 aaagatgcct ggtccatatt caaagaaata tatgtgcaaa agtaagagtc agtgacagaa
     2521 aagaagtggc caatgaattt aaagaggtat atcggtccaa atcaaaagaa gaagctttaa
     2581 cttctctaaa gaaattcatc gataggtgga aacacaaata tccatcaatg gtgaaaagtc
     2641 tcagcaacaa tgactatctg tttacattct atgattatcc agaaagtgtt aggcatacga
     2701 tttattcaac aaatctgatt gaaggaaaca ataaacaatt aaaacgaagt ttcaaaaaga
     2761 aagaacaatt tccaacggaa aaatctgaag agaaatacct tgtgattcag ttcaatcgtt
     2821 acaacgagaa aaacatgaat cacgtacata gaggttttgg acaaacaacc agagaagatt
     2881 ggttcaagag ctaatctgct ttaccaagga tatactttta cacaaaatta ttgacgctcc
     2941 caaatttaaa cgattatgac attaaaaata tattttatga attttctagt atataacttg
     3001 atttatctgt taagatttat taagaaaacg ttttcttatt tttgatttcg aggtgataga
     3061 caatgaaaaa taagtttatt ttatctttag gtattttaac tattggaatt agtgtaactg
     3121 gaactacaat tcctacattt gctgatagta caaatgaacc aactactgta gtagataata
     3181 accaagaatt aactccttta gataggaacg gaatagccat tggtaaccca actaacgact
     3241 taactgttac tgaaaattat ttaatagttt ctccattact tgctcgagca gcttctaaaa
     3301 cgatacgagt gacaggaacg atgatttttg ataaagttgg ttggccttct agacctcctc
     3361 aatcacggaa ttggaaagaa aaaagaaatg gttattggta ctatggaaaa ttgtatttac
     3421 aaagttataa atcagctgga aacaattgga ttgcgactta ttcaggaacc ttaactagaa
     3481 agtagggatt ttttatgcca gaatttgtga acacaccaaa tttttatcaa gatagcgata
     3541 ttctaagtaa aattaattta ccgaaagaag aatcagcttt acaagttcag cgaactttac
     3601 aggagacaca aaaaattcaa aaatcaattt ctaatctaga agattctgaa gaaaaaagaa
     3661 aaaaaagaga ccaaaaaaca tatcaaaaag aaaaataatg attttaaaaa aagagtgtct
     3721 agtcgacatt ctttttttct aattgaaagt gttcataaaa tcacccattt ctggacactt
     3781 t
//
LOCUS       DADVXM010000129         3419 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.136, whole genome shotgun sequence.
ACCESSION   DADVXM010000129 DADVXM010000000
VERSION     DADVXM010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.136"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(528..1838)
                     /locus_tag="KB927_002560"
     CDS             complement(528..1838)
                     /locus_tag="KB927_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBB6841435.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1850..3268)
                     /locus_tag="KB927_002561"
     CDS             complement(1850..3268)
                     /locus_tag="KB927_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6841436.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
BASE COUNT         1058 a          686 c          529 g         1146 t
ORIGIN      
        1 taaaaagttc gaacaatctt gcgattgtta agctcaattt gtttgctagc atattgcttg
       61 cttgttaaaa atgtttattg tcttgaattg aatcaagacg ccctacacat ttggtttgtc
      121 ttactttgtt cagttttcaa aggtctactt catcgagagt gtttcccgat tcatttttgg
      181 ctgccgtagc aacttttata tcatatcaga gagacaaacg attgtcaact cttttttaaa
      241 agtttttttc gatttcgttt ttcgaaatct ttcagcaact catttatcat aacttatcgt
      301 ttgttatttg tcaagaactt ttttgaagtt tttttcgata gaatcaagct tcgcaagtgg
      361 ttctttttaa cgacttagtt atcttatcac gtctaaaaac atgtgtcaac tcttttttgg
      421 aattttcata aaatgtttca atgaagcgcg acaacgttgt ttaatatatc attaaaaaaa
      481 ataaaggtca agctaaaata ttatttaagc ttgaccttat tataatttca acgattgtca
      541 aaagtattgt ttgcagctgt gttgccagtt tctatagata aatcacagct tttgaaacat
      601 aagttttgta ctgcttcgat tcgcccgaat tcttttgcag ttatttggca atgagaaaag
      661 cagacatctt ctataggctt ttcaggaaat gctactaaat caaaagctcg ggaaggaagt
      721 gagtaacctg gagaaaggca tgcctgtacg tttttgatgt gtatgtcttt gactttcgtc
      781 atttgctttg attcaggtat ttcttcagcc actgcttgcc aactttctgg catttgagca
      841 aggtcattgc tattttttct attgtattca ttatgccagt ccattatcca agaaaaagga
      901 aattgtacat caatcatatt cagattttct accctgatat tttcgatcac tccccctctt
      961 tcttttgaag atttcattcg aataccacag tctgactgaa aaaaatcgat atcgtgaata
     1021 tatacgtcac taactccagc actaacttcg ctaccaatag ttacaccgta tcctgaacgg
     1081 attttacatc tagcaacctc gattcttgat gattttcgat tgactcttgc accattgcca
     1141 tctctgccag acttaatagc aatacaatca tcaccacagg ccaaatcaca ttcatagaca
     1201 cgcacatttg ttgaagaatc aatatcaatc ccatctgtac ttggtccatc attgttgcgg
     1261 atgattactt tttctactaa tacatcgtta gaataagtga tttgcaagtt ccaaaaacct
     1321 gatttctgaa aaatcaaatc acgaacaaca acatgttctg catgatacag taaacaagcg
     1381 cgtggacgtt taatagcata atccgcaatc caacgaagtc ccttttgatc gtattcagct
     1441 cttgtcccgc ttttttgatc ttttccccaa tacagctccc accaatggtc tccttgaccg
     1501 tcgattattc cttttccttc tataagaata tctttcgccg agagaacatt caaaatcgct
     1561 gctggccatt tcatttctac gccggctact cgtgtatcga tttctggaaa tgcttcgata
     1621 tctgttctcc ccttgaggac tgcaccttct tcaaagataa gatgactctt atcttttaaa
     1681 aaaagggctc cgactaaata aatgcctttt ggaataaata caggtaagtg ttctttcgca
     1741 ccttgatcga ttgctttttg cagtattatt gtatcatctt gttgagtgtc gtttgtttta
     1801 aagttcaaag cattgataat cccttttttt gtccgcaata cgtttctccc tatctttcat
     1861 tgattttttt caattcttca ccaataaata cagtttttga acgattcagt gggtaaccta
     1921 ctagcaaaat gattgcggat acaaataagc agaatgctgg taacaagttt gccatcgtat
     1981 aaatcctttc ttgtactaaa actgattgga tggctccacc tgttgtagac gattggtaac
     2041 caatgagtgc cagcataaat ccgcctaccg ctcctgcaca tgcttgtcct acttttctcg
     2101 caaaagaatt tactccatat actgttccat cttctcttaa gcctgtctta tattgatgat
     2161 aatcaatcac gtcagtaatg aatgcccaga ccatcaaatt gaataaacca gatcctaaag
     2221 tagcgataaa taaaagaatc agatataccc atgcatttgt tatatgaagg aaatacatca
     2281 gcaagtacat acatgaagaa gcaagtaacg caaatacgct tgcttccttt ttaccaaata
     2341 attttgtcag ctttgtagca aatggtgcta aaactactac tgttccgtaa gtaaataaaa
     2401 gagcaacaga cattgcttgt ttattatgga agtaatcatt gaataaataa gtcatattcg
     2461 tcccagctaa aatctgattg atcacaatga aaatgtcaac aatgactaaa ataatcagtg
     2521 ctcgattagc taacaaacct tttaccaact gagaagcaga tactttttcg tttttgacaa
     2581 ctcttactct ttcagtagtc aatttacaag ttaacatata tgcgacaaat gctattgcag
     2641 cacatccgat tgaaatccaa aagaaatgat tccctgaaac gacttgttgt ccactcttgt
     2701 tatgggtata cattaaaatc ggaatgaaga atcctgtagt tgatccgcca atcgcagaac
     2761 caatgcttcg gaacgtggac aacgaggtgc ggtcattagg atttgagcta attgctgctg
     2821 ccattgctcc atacgggata ttgattgttg agagaaaaat cccataaaca atgtatgaaa
     2881 caaaaatata agcaatcttc accgtcattg gaagatgttg gacgaatggc aaaaacaaaa
     2941 tgacagtcac taagcaaaat ggatacttca tttttctgat ccaaggaata aatcggccag
     3001 tttctgttaa ctctgagaca tcacataatc ttccaaccat cacatcagca aacgcatcca
     3061 aaattctcga aatcaagaat aacgtaccta cgattgcccc tgaaacgcca agaacattcg
     3121 tataataaat catcaagaaa ctattgacta aacctaaaat aaaacagtta cctagatcac
     3181 cgaacatgta gcctatctta tcggaaatcc caaattcctt tttttctttt tttattgtat
     3241 ttgctgtaac agcattttgt gaaagcattt gaattcctcc tacctcttct agtaaacgtt
     3301 ttcaaaatta taactctttt tttcttgttt ttatattcac aatgttggct ttttattgca
     3361 ttatcttgac agataaaaaa caaaaaataa tctaaaaaca ttgatgcata agattgata
//
LOCUS       DADVXM010000130         3334 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.137, whole genome shotgun sequence.
ACCESSION   DADVXM010000130 DADVXM010000000
VERSION     DADVXM010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.137"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..2232)
                     /locus_tag="KB927_002562"
     CDS             complement(<1..2232)
                     /locus_tag="KB927_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841437.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="KB927_002563"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="KB927_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          916 a          745 c          538 g         1135 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatg
//
LOCUS       DADVXM010000131         3274 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.138, whole genome shotgun sequence.
ACCESSION   DADVXM010000131 DADVXM010000000
VERSION     DADVXM010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3274
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.138"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..171
                     /locus_tag="KB927_002564"
     CDS             <1..171
                     /locus_tag="KB927_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBB6841438.1"
                     /translation="SLFPLYHGSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFK
                     IEYTKKRQRLAY"
     gene            406..642
                     /locus_tag="KB927_002565"
     CDS             406..642
                     /locus_tag="KB927_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841439.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            649..2601
                     /locus_tag="KB927_002566"
     CDS             649..2601
                     /locus_tag="KB927_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBB6841440.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="KB927_002567"
     CDS             complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="KB927_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBB6841441.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT         1155 a          543 c          575 g         1001 t
ORIGIN      
        1 tctctgttcc ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata
       61 gaagttatta ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga
      121 aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatta agtagttcag
      181 ttttggagta caaaaagtga aaatgtaaac ctaaatgagt atcaaattgc aactgaattt
      241 gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag
      301 ttaaaatgta tataaaaatg cgaacgtgaa ataattattg taggaatgca aattggtgtg
      361 ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt ttcctatgca atttcttgag
      421 ccaaaaaata agaacgctaa gtctgtggat tgggaaatat cagagcaagt aagggtgata
      481 gttaagcaat acgctgaata tgcagagcgt actgaaagcg aagcagtgga tgaattctta
      541 ttgaacattt tagacgataa gaagtttatt gaatggattg ccaacaagcg aagtaataag
      601 cggattgttg aaaaaatggg tatcaaagat agagtgggtt gatagacaat gaccaagctt
      661 aaaagattag ccacgaagga agatgaaatt gtagatgtta aaattccgat ttcaaacgaa
      721 gaattaaaag atagggctaa acaatatgat ttattaactc caaaacgatt tgcaacaagg
      781 tataacaaaa tgttgttctt gccaacgtct tttaaatgga acggttctga atatcccatt
      841 caatataatt actgcatcaa tccgttttgt tgtaattttg ggaaagaaca gcacaaattc
      901 aaagatgtaa aagggaaacc aagtcgatat aaaatgactg gtagttccaa agataaaggt
      961 cataaaggta tgtactgcaa tgacaatcct attggcagag gtgtatcgca aaactgtaca
     1021 gtaacccctt tatctaattg gtctgttgtt gaagaaatta aacgccttat agaaatcaat
     1081 agcatccaag atgttgagcc agattatcaa tttcataaag aaggctgctc ggaagaagaa
     1141 tcaaccccat tcaatgagcc gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct
     1201 caacgctatc aatgtaaggc gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa
     1261 accactactt atcaccaaca aaagaacacc attcttccaa tgttcgctaa gatggttgtt
     1321 ggaagggttt cagtcagtcg tacttgtgat attttaggaa ttggagttgg aacctactat
     1381 cataagctgg agtggctgta taggcgttgt ttggagtttt tagaacgata tgagacacaa
     1441 ccccttcaaa caaagaaatt taacgagatg tggcttaata cggacaagat gcactactac
     1501 ctaaataacg tccgtaagaa aggacaaggt tcaaagaaat atacggggtt tgaagacctt
     1561 aatatgcaaa cgtatatagt tgtatctgct gaggtcttat caagatatgt gttccgttct
     1621 gatgttgcct atgattggaa tatttcaatg gatgaattaa atgaagatac aagaaaattc
     1681 aaagaagacc atctcaatac ttttagtcgt aaaaatgata ggttagattg gtcttattat
     1741 ccacaagaac catccgctaa cgatagcgaa aataggaatg cttatcttca cgaattaggg
     1801 aaaattacta ataggagtag atttgtcgat ggtttaaatg ttgatgctcc ttatactaca
     1861 actgctcact attggttaat taaacaaatg gttaatgccg acgaatggcg aatgattagt
     1921 gatgatgact tctctattag aaacgccttt tatagagtat tcacgaaaga attaaggttg
     1981 agcgatgcac atcattttat ttgccaagtt aacaagacga aaagcagaaa acaatgctta
     2041 aaagaattcg gacaagcaaa agcagaactg ctcgattggg gagatatcag aggattcaaa
     2101 acaaagtttc tacggacttt ggcatctcat tatctaactg aattactaac aagtcatcaa
     2161 ttccacgaag aggctattag taaagatgga gaaagatatc gcaaatatgc cgataaccct
     2221 atcaaacatc cattagccac taaggataaa ggattttatt cagttgattg tagaacggat
     2281 ttatctgctc tggaaccaaa cgaaatcgca aagatgctat taaatgttaa tgaccattcg
     2341 accaatagct ttattcaaca gataagacgt tatatatcat ctcttgaaag accattaaca
     2401 acagctcgtg gtgataagaa gagctatatt tacgctaact tcaatccgaa gtatgctcaa
     2461 tttgcgatta caattctaag aacttactac aacttttgtc gcccttttaa atcagcggat
     2521 aaaaaggttt tgacacctgc tcaaagatta gggattacag ataaacaatt tgattggaaa
     2581 gatataattt atttcaaatg acaaaaagag cttggagtaa tcccaagctc ttgtgcttta
     2641 tctttactgt tcttcttcaa ttaacgcacc cgttaactca ataagttttt tctttcatat
     2701 acatgaaaat agtagttata cggattttta tcattcttta tccctttttg ggcaaatacc
     2761 tcattccatt cctcataatt cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt
     2821 atttttgtga tgtacatttt ctcaacataa gggaaaaaca aattataaat ctgttctcct
     2881 ccgaaaataa aaatttcttc ttcgttttta cataactcaa aaacatcttc tattgaatga
     2941 acaatttcac aaccattaaa ggtaaacccc ttatctctcg tcagaataat atttcttctg
     3001 tcaggtaagg ctcttccgat tgattcaagg ttcttcctac ctaatattat cggatgtccc
     3061 tttgtagtat ttttaacata ttcccagtcc ttgggaatcc tccaaggaat gtcattctct
     3121 ttgccaatca ctctattctt atccatcgca gcaatcaaag aaactttcat ttataacaca
     3181 gcctttttaa ctaatttacc atctaatttc ttatttctat caaaaaacct tttctcatta
     3241 tcctgcccgt tagttgaata agcaattttt tcta
//
LOCUS       DADVXM010000132         3221 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.139, whole genome shotgun sequence.
ACCESSION   DADVXM010000132 DADVXM010000000
VERSION     DADVXM010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.139"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(438..1052)
                     /locus_tag="KB927_002568"
     CDS             complement(438..1052)
                     /locus_tag="KB927_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6841442.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1658..2035)
                     /locus_tag="KB927_002569"
     CDS             complement(1658..2035)
                     /locus_tag="KB927_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841443.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2335..3216)
                     /gene="galU"
                     /locus_tag="KB927_002570"
     CDS             complement(2335..3216)
                     /gene="galU"
                     /locus_tag="KB927_002570"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBB6841444.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT          978 a          660 c          499 g         1084 t
ORIGIN      
        1 ttgtgtattt tatttctatt agaaaaaggt atcctgttgg acaattttgt tatatcaggt
       61 aaacttcatt gcaataatga taacaaatgt actataatta ctttgtaaag agttttgggg
      121 aagactcttt catcaacgtg tattaagaga caagaaagaa tccatatgga ttctttcttg
      181 tctctttttc cactactttt tatttttctg acactacata ttcttataac tcatttctca
      241 taactgtgaa acaacttata aaaataacaa actttaaaca aaacaagctt aaaatcaaag
      301 atgatccatc ttaaaataac taaaacaaaa aaagtagtcg ttgttaatcc tcattaataa
      361 tcgttttctt tttttcaaac gctccatttt tatgtggaac attatttttt taaggaactt
      421 tgtcaacatg tggataacta ttttccactt gtgtcctgga ctagctgttt tgctgtaaaa
      481 tacaaaactt gctgcagcaa aaagatcgtt gcaagagagg ctgttccgca gatcgctgga
      541 tctagatttg gcaaagtcaa gactgcatca tgtaaattgg cgtggttgtc caaaaccaaa
      601 tcagcaaatt caaataatcg caaaccactg ctatgttgcg atttgatact tcgtgacaaa
      661 tcaaatccag taacaatgat taatggatga ccattttctt tgatccactg agctagttcg
      721 atgattgccg ggtttcttcc ttcattcgaa agaagaagaa aaatgtcttc tgatttgaca
      781 gaaagctgat caataattgc ctgtcctgca ccttctagcg tttcatagac acctccggct
      841 ggattttcaa tcaatatact tggtacaaga tccggggttt gatcccaaaa ttcaaatgct
      901 acaccactta gtgtgcggct agcatatatc tgcaatctac caccttgatt aatttgtttc
      961 gcgatccaag tgccagcttg aagcatcagc ggctcttcta tccttaattt ctcttccaat
     1021 tggtgataat agtcaaaata acataaactc atttatctct cccgcctagc tatacttgac
     1081 atgaatagaa acagctgcct aatctaagga agtacataaa aaaacagtag ttagacagta
     1141 acacatgtgg tctttgctgt ttcaaacaca aaaaaggcat tgaacgaata cgcccaatac
     1201 cttgacatag caaataaaac aacgtgcaga ccatggaaaa tatctacata ggggtagaat
     1261 tttcacccta gattaggtac aataaattag gtcgatgcac tgcattgact atggcaaaat
     1321 gatcggtcag ggtgtatgtg tgtgactggt cattccctga ttcttagcgc caactaaggg
     1381 tcagggagcc tttttttatt cagctgtttc tatctgaatt tattgtaagt aatctcttat
     1441 ccaagtgcaa gcaagaaaat acaaaaaaac attggtatga tttatatata tataaataac
     1501 ataaaaaaag gaatggctta tcccgataca acaagcattc ctttaaaaaa gattctttta
     1561 tataagtgaa aaaagctttt ttccaccaat taaataaatc tctcatctca atagtttatc
     1621 cattatttta tctttttttg cgtataccta ctaaatatta ccgtcttctt ctcgttcttc
     1681 tactttgttc gagagaatct gtactagaaa aagtagttgt atgtctacct tttctgccta
     1741 tccgagactt tcttttcata tatgggatat aaatgattag atacagtaca gcaaaaaata
     1801 aagcaaatac gcaagcttcc caactaccta acgccaattc aaccatcaag gtagcaaccc
     1861 caacggatgc tgcataccag ataaaaatca gaaacgtttc tttttttctg accatgcgaa
     1921 acatgataaa tagactaata agcaatagtg gcaacacaaa tatccaattg cttccttcca
     1981 tcagccactt gagtatatca agcagcgact gtgcaacagc gactaatttt cccatagtga
     2041 acacacacct ttttttataa ttaaaaaatt cgccttttta ttctactatg aatcttctgg
     2101 cttggctttc atttctctta tgtaatcatt ttcttttata caacttaaaa aaaaattaaa
     2161 ccattagcat aatattttct gaatctattc acgaaagtct ttttctatct ttcgttttcc
     2221 acgactcaac tgatctagag tcaaaaaact aaaacgacag ttgcgcaaat gacgcacaag
     2281 ctgccgcttt aataacaaat agcctttcat tctcagcagg ccacttattt ccagttaact
     2341 ttctgttctt agctttttac tcaactggat aatatatgca cttaatgaag tcccaatttc
     2401 cgaatgttga agtccatatt caatatttgt cttcatatat cctaacttat cgcctacgtc
     2461 gtatcttttt cctttaaact ctctcgcata gaccgcctct gtctggttaa gagtctgaag
     2521 tgcatccgtt agctgtatct cgtttcctgc tcctggttct tgagtttcta atatctcaaa
     2581 tattttagga gtcagtagat aacgtccgat aatggctaaa ttacttggtg cttttcccat
     2641 ttcaggtttt tctacaaacc cttttactct gcaacgaccc ttttcgctat ctgttttagg
     2701 atcaataatt ccgtatttag atgtttcatt ttctggtaca cgcatgacgg caacagcgga
     2761 agcttgtgtt tcttcataat ccatcatcaa ttgttgagtc aatgggatat catctttcat
     2821 caaatcatcc cccagcatga cgacaaacgg ttcatttcct ataaatgctt ttgcttgaag
     2881 cacggcatcc cccagtcctc ttggatgaga ttgacggatg aagtgaagat tgacttgagt
     2941 cgtttcttca actaaagcga gtaattctgt tttttccttt tcccgcaaat tgttttccaa
     3001 ttcgatattt gcatcaaagt gatcttcaat gggtcttttt tcttttcccg ttacgatcaa
     3061 gatgtcttcg attcccgaat ccaatgcttc ttccacaata aactggatcg ttggtttatc
     3121 cacgattgga agcatttctt ttgccatggc ttttgttgcc ggcaaaaaac gtgttcctag
     3181 cccagcggca ggaatgactg cttttttgac cttcacttgc t
//
LOCUS       DADVXM010000133         3168 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.140, whole genome shotgun sequence.
ACCESSION   DADVXM010000133 DADVXM010000000
VERSION     DADVXM010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3168
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.140"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(69..2561)
                     /locus_tag="KB927_002571"
     CDS             complement(69..2561)
                     /locus_tag="KB927_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBB6841445.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(2568..3035)
                     /locus_tag="KB927_002572"
     CDS             complement(2568..3035)
                     /locus_tag="KB927_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBB6841446.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT          843 a          697 c          518 g         1110 t
ORIGIN      
        1 aaaaatcttg tcacaacctc ttaatcaagt cttactatta taaaaattca gctacacagg
       61 ccaagtaact atagggaacc tactgtttcc tttttaggtc cgcgaacatt caatgtgatc
      121 ttaccttttg aagcacctac tgttacgtgg tcacctaaac gaatttctcc gccaagcaaa
      181 gcctcgctca atcgatcttc aatttctttt tgaagtgcgc gacggattgg acgtgcacca
      241 tattcaggat caaatccagc tttcccgatc acatcgattg cagatggtgt gattttcact
      301 tgaatatctt gttctttcaa tcgtttgata atcgctttgc tcatgatttg gacgattgta
      361 tggatttcat ctttactcaa tgaatggaag acgacagtct catcgattcg attcaagaat
      421 tcaggtcgga aagctttctt taactcttct aagatacgtt tttgcatggc tttgtgatct
      481 ttagtaacat cttggacatt gaatccgaca tttttttctt ctcgaatttg tgtcgctccg
      541 atatttgaag tcataatcat gattgtattt ctaaagtcca cttttctacc tttagaatct
      601 gttaaatgac catcatccaa tacttgcaga agtaaattga aaacgtctgg atgtgctttc
      661 tccacttcat ctaagagaat cactgaatat ggtttttgac gaattttttc tgtcaactgt
      721 ccaccttcat cataccctac gtatcctgga ggagacccga ttaatcggct tgtactgtat
      781 ttttccataa attctgacat atcaacacgg atcagggcat cttcacttcc aaacatgact
      841 tctgaaagtg ctttggccaa ttctgttttt ccgacaccag ttggtccaag gaacatgaat
      901 gaaccaattg gacgatcagg atctttcaat ccgcttcgtg cacggcggat cgcacgtgaa
      961 actgctttga cagcctcatc ttgaccaacg acacgttcat gcagaagtcc ttccagttct
     1021 aacaagcgtt cgctttcttt tttctccaac tgctgtagag ggacaccagt ccactccgat
     1081 acaactgtag caacatcttc ttctgttaca cgatcagaat aaccttgctc ctgttttgct
     1141 tcaattgcag aaactttttg cagcttttta cgtagtgctt tttcttgtct gcgtaattga
     1201 gcagcatttt caaagtcttg tttttggatc gctgcttcct tttcttgtac tagttcatcg
     1261 atttctagtt tgatcacagt tgattttgtt aagtgatcgg tttgatccaa acggactttc
     1321 gctgctgatt catcgatcaa atcaattgct ttatcgggta gttgacgaga agtgatataa
     1381 cgaacagaaa gattgactgc tgctcgtaca gcttcatctg tgatctccac tccatggtgc
     1441 tcttcatatc ttgtacgtaa tccttgaaga atcacttctg cttcttcagg agttggctca
     1501 tctacttgaa tgcgagcaaa acgtcgctct aatgcagaat ctttttcgat atatttttga
     1561 tattcatcta gggtcgttgc tccgatcgtt tgtaattctc ctcgagctaa cgccggtttc
     1621 aagatattcg aagcatcaat tgctccttct gctccacctg caccaattaa ggtatgcaat
     1681 tcatcaatga ataagattac ttgaccatca ttatagattt cgtcgatgac ctttttcatt
     1741 cgatcttcaa attcaccgcg atatttcgta ccagcaacca aagatcccat atcaagcatc
     1801 atcaggcgct tttcttgcat gtcttctggc acttcaccta aaatgatttt ttgagctaac
     1861 ccttcagcaa tggctgtttt gcctacacca ggttcaccca ccagtacagg gttattcttt
     1921 gtccgtcggc taagaatctg gataagccgt ttcacttctc tcgaacgacc aacaactggg
     1981 tccagcttgt tttcttttgc taatttcgtc aaatcacgtg ctaatgaatc tagcgtaggt
     2041 gttccttgcg gtgtttgccg tttatcttgt acatttacat ttctacgacg attcattcct
     2101 tttccagcag aatcaccagc tagccccatt ttttgtttca gaacttgacg ggcttttgaa
     2161 aggctgatac ctaagttgat catgattcga gtagccatga tactttcatc ttttaataag
     2221 ctcatcaaaa tatgttctgt tccaactttt tgagaaccag ttttcttcac ttcgctgcta
     2281 gctaaagcaa aaacttgttt cattcttggt gaatatggaa gaaagactcc tttagggtaa
     2341 gaacggatac caccataacc aatcagatgt tcaatttctt cataaatttc cgtttcattc
     2401 aaatccattt cacgtaatac ttttccagca attccatttt gctcgaccac taaggctagt
     2461 aaaacatgtt ctgaactaac tgattgatgt ttcaaccgtt ttgcttcttc ttgtgcaatt
     2521 tctaatactg cttgggctct ttcagtaaaa agttcttcca tctaatctca cttcccatct
     2581 tcataactta aacgttccag aaatgctcgg agaatccgag cacgtgtatg atcttcatat
     2641 tcattgaaat tcaatgtgtt ttttgcaatt gcactcaaca tcaagtttcc ttcttttttt
     2701 gtaattattt ggtcttcata aagtttttga ataatagcaa aagcattttt ctcactgatt
     2761 gtatcatcaa ataactgatt tatctgctca agtaattgtt ttttatctga aatccttact
     2821 tttgcaattc gtatataacc accaccacca cgtttgcttt ctactagata accacgttgg
     2881 atggtaaaac gggtattaat cacatagttg atttgtgaag gaacacagtt aaagaggtct
     2941 gccatttcaa tccttcgaat ctcgatcatt tcactatttt ccagaatttt ctttatatat
     3001 gattcaatta aatccgaggt attctgatgt gccatcttat tcattccctt tgactaatat
     3061 tgaccttaat tataacgaat ttgataatag aaagaaagaa gaacgctttt tgttaaataa
     3121 atcctttaga atcaacaaaa aaaaatacgg aatatactat tccgtatc
//
LOCUS       DADVXM010000134         3116 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.141, whole genome shotgun sequence.
ACCESSION   DADVXM010000134 DADVXM010000000
VERSION     DADVXM010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.141"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..2023
                     /locus_tag="KB927_002573"
     CDS             <1..2023
                     /locus_tag="KB927_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6841447.1"
                     /translation="TLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISL
                     NSESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLS
                     DYEFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISV
                     VYVDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRK
                     IGENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNM
                     IYLALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHS
                     VHLAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKR
                     NGLLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDD
                     RIQRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTF
                     EIEFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGK
                     GWFAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSAL
                     SASLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            2020..>3116
                     /locus_tag="KB927_002574"
     CDS             2020..>3116
                     /locus_tag="KB927_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBB6841448.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYC"
BASE COUNT         1179 a          424 c          526 g          987 t
ORIGIN      
        1 aacactaaaa gaatcagatt tttttcatgg aattcaaaat gggtggcaag ggcattggat
       61 tattatctct gcgacatttg aaggaatcag cgaagaagaa tttgacaatg agatttgtgc
      121 ttccatttct ttaaattctg aaagtcaaac aatcttagaa gaattgattt caaatgcaga
      181 taaaggtgta ggtagtattt ctctatttat tagacctaac aaagctatta gaaagcaatt
      241 atttgatatt tccactgaat tagactctca tcaatttaac gaatttagaa attctattcg
      301 tctatccgac tatgaatttt actacacatc taaatcaaat ctaaatttct gtatcaatga
      361 aaattatgat aaattggtag gaagactcaa tgacaatata gctagtaatc ctgaagaaga
      421 cgatgaagct ctgttgggct caagaattga catgtcagat attttcaagc atatttcggt
      481 tgtttatgtt gacgctcttc gagatgttct tagagaaatg aaaaacaatc gaaacccagt
      541 caaaagaatc atggaaacaa ttgaatcaaa aatatcatca gataatgttg agtcattaaa
      601 aacaattata cagcaattaa atgagactat taccagtgtt cctgaaatta ggaaaattgg
      661 cgaaaatatt aatcggcaac taaatagcat aattggttca gtgtattctc ctaatcttct
      721 tctttcctca actatgtcag atgatatggg ttctttagca aaatttcttt caatgaagcc
      781 agaacaaaat atcgacttag acttactagg gttaggacat ctaaatatga tttatttagc
      841 tttgaaaata gtcgaatttg aagcgtgtcg ttcaagagaa ctacttaata ttatgttgat
      901 tgaagaacca gaagctcata ttcatcatca tattcaaaaa actctgttcg aaggattaaa
      961 tcttcaaaaa aactatactc agattctcat gaccacacat tctgtacatt tagctgaagt
     1021 gtctgaaata tctcggatga atgtattaaa atcgtttaat ggcaaatcta tcgttatgaa
     1081 tccagcaaat aatctgaact catttgctaa agaaaagtta aaaaagaaca atctaaatct
     1141 aataaacgca gtagagagat atttagatgt taaaagaaat ggattgcttt tttctaaagg
     1201 tgttatctta gttgaaggag atgctgaaga aatacttatt cctcaaatag taaaaaaatt
     1261 atttggtata aacttagacg aacttggaat aggtttgatt aatgttggta gtacttcgtt
     1321 tgaatatatc gctagcttgt ttgacgatga tagaatacag agaaagtgtg ctattgtaac
     1381 tgatttagat gaacaggcaa tcccatcaga acatcgattg tataaaagca ctgcacaaga
     1441 gaaaggtcaa gcaagaaaag aaaaattatc ctcccttttt aatgaaaaca attgggttaa
     1501 ttgtttttat gctaatacaa catttgaaat tgagttttta gatgtgaata aagaaaatat
     1561 tctaacttat gtcagtccaa ttatagatga cgcattcaaa gataaaaaaa caataactgc
     1621 ttataaagaa gaaatacaaa gtgaacaata tttagaaaga aatttagcga tgttaaaact
     1681 agccaatcat gttggtaagg ggtggtttgc aattgagtta ggtgaaaaaa ttgacttttt
     1741 aatcaaaatt cctaagtata ttcttaatgc tattgctttt gcatgtcagg aaatagtaga
     1801 tctctcaatt tataaaaaaa ttctactcca tacaatcgac ttgtacgagg aaactacaga
     1861 attgtcagct ttatcagcta gtttaaaaac aagtgataca gctgatttga atatagcaat
     1921 aatttcttta ttagagtact ttggtaaaga tgaggatgtt gtgtatctaa tcaatcagat
     1981 agaaaattac acaaaaatac tttatgctga ggtttcaaaa tgacaaatat cttcgaaaaa
     2041 atcgtaaatg atttaaattt agaacaaaaa gatgttgtgg aaagtgaaga taacctttat
     2101 gtaaatgcat gtcctgggag tgggaaaaca agggtactta caaggaaaat tgcttaccaa
     2161 gcaattaaac acgatggatc actaaaaaga ataattgcta tcacatacac taatagagct
     2221 gctgaagaaa ttaaggaacg cctaagttta cttagtatag atgatgatat taatatttgg
     2281 gtggggacaa tacatcagtt ttgtcttgaa tttattattt atccttttaa aatgaatctc
     2341 tcaagagtat caaaaggatt tacaattatt gatgattata ctcaaagagc ttacgtcagc
     2401 caaattaata atatgctgaa tttaaatctc aaaacgtatg aactgaacaa aattgatttg
     2461 tcactttctc atgattttaa aattaatgaa gttcagtata ctcaagtttc tgaaatgtat
     2521 cacactatgt tggaaaaaaa taaagaaatt gattttgata tgattttact agtagcgtat
     2581 aaaattttaa ctgtaaacag taacgttgca cgtaatattg ctagtaatat aagggcgatt
     2641 tatgtggatg aatttcaaga tactagagaa ttacaataca atgtaatagc taaattactt
     2701 caaaacaacc ctcaaattca gtcaatgttt gttggagata ttgaccaagc aatttatgga
     2761 tcattagatg gtatagctaa atcagttgaa gaactagaaa tgctaactag tcacactttt
     2821 caatcaaaga cgctacatgg ctgttacagg tctaatcaga gattagtaga cttctactct
     2881 aattttcaga gttgtcctta cgagattgaa agcagaggga ataataaaaa cgaccgtggt
     2941 tttataagtt atgattgcaa agttactaag gaggatttac ccaacataat aaaaaatata
     3001 ataaaggaaa agattgaaag cggcattcat gaaaaagata tttgtgtact tgctcctcaa
     3061 cactatcctc tgttttcact gggtgagtat ttaaagaaag aattaccgta ttgcaa
//
LOCUS       DADVXM010000135         3070 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.142, whole genome shotgun sequence.
ACCESSION   DADVXM010000135 DADVXM010000000
VERSION     DADVXM010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.142"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(334..696)
                     /locus_tag="KB927_002575"
     CDS             complement(334..696)
                     /locus_tag="KB927_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841449.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(770..1150)
                     /locus_tag="KB927_002576"
     CDS             complement(770..1150)
                     /locus_tag="KB927_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBB6841450.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1214..2407
                     /locus_tag="KB927_002577"
     CDS             1214..2407
                     /locus_tag="KB927_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6841451.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2484..3068)
                     /locus_tag="KB927_002578"
     CDS             complement(2484..3068)
                     /locus_tag="KB927_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6841452.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          958 a          587 c          504 g         1021 t
ORIGIN      
        1 aacgactcag ttatcttatc atgtcgttag taacatgtca ataactattt tttaaatttt
       61 ttagaaatgt gatataacat ccacttcaga atcaacgctg ttaaatttat catgtatttc
      121 ttccttggtc aactataaat taagcattac tttgtgaaat gatttttcga tcaattatta
      181 ttattcgtta tacaaccgtt ttcaacatat tttgaaaata aaatgcacta aaaaactatc
      241 tttagcagaa catttcattg tattttttgg accaaacaat aaaaaaagaa gtttgaaaaa
      301 aattcaaact tctttgttcg cttaatctgt attttagaag aaaggcactc cctctacttc
      361 gtaagttcca agaacagagc gcatttgacc tggttcttcc caaatatatc cttcgcctaa
      421 ttcttctctt tgattctttt gttcagtttc aaagacaaac aacggaacat tttcctcttt
      481 aatatgtgta tttgtcaatt ccatcaaact aatcttgcta acatcgatat gaactatttc
      541 ttttaagaaa ttaagtatat tcgctaaacc agtctttcct tcagaaagtt ccgctaacgc
      601 aaattccaac ttgtcatcaa ttgaatggac caaaaatttt ttagtaccat cctccaaatg
      661 caacataatt gtaccagcaa ctcttttgct tgccaaaatt tccacctcga tcaacttgtt
      721 ctatggctta cataaaaatt ctagcacatt ttcagaaaaa atacactttt tatttcttat
      781 tttctttccg ttctagttca gataatgctt cttctatcca aataggtaac tgctccgcaa
      841 tagtggtaaa tccgatctta cgatttttat tcgtgaaata cctttttctg cgatatggaa
      901 cagctggatt tgttttttct aacgttctta aagataaact gatttttttg gaatattcat
      961 caatgtcgat gatctgaact gttactggct gtccgacttt taacaatgaa tggatatttt
     1021 tcgtataacc ggattgtact tctgaaacat gaataagtcc ttgcgtctcg ttatcaagag
     1081 aaacgaatgc gccataaggc tgtatccctg tcacttttcc ttcaattatt tgtccaattt
     1141 tataagtcat ctacttccct ctcttcgcat ttatcattat actgtaaata gctcaaaaaa
     1201 agaagcgacg aaaatgactg gaggtcttaa gatgatcgaa tttgataaac agatttcaag
     1261 aaaagataca gaaagtgtaa aatgggacgc aattgctgag acatatcaaa tggatgactt
     1321 acttcctttg tgggtagcag atatggactt cttgtctccc ggtggggtag ctaaagcgtt
     1381 tagtgaatac atcaaacatg gaatctttgg ttatgccact ctgtctgata aactatatca
     1441 ggctatcatt cattgggaac gccaacacca tgctgtggag ttgacgaaag aaaatatcgt
     1501 ttttacaagt ggtgtgttaa ccagtttagc tgcagcagta caaactttta caaaaccagg
     1561 cgattctatt ttgattcatg acccagttta tcctccattt tcctctatta tagaaacaaa
     1621 tcaacgtcac atcgttcgaa gctctttgct agaaaaaaat aatcatttca tcatggactt
     1681 gtctgacatg gagaaaaaaa tcgaagaaaa caatgtaaaa gcaatgattt tatgcaatcc
     1741 tcacaatcct ggagggcgtg tttggagcaa agaagaattg aaacagttaa gcgaattgtg
     1801 tttaaaacat caagtgattc tgtttagtga cgagatccat caagatttaa ctttattcga
     1861 tcatacattt acttccatgc taacgattga tcctaattta gatgatctac tagttgcttt
     1921 tacttccgca accaagactt tcaatctagc tgcaatcaaa aattcaatgg tatttatcaa
     1981 aaatccagag atgaaagctg attttgaaaa acatttagtg atgaaccaac agcacgaaat
     2041 caacactttt ggactgattg gaacccaagc ggcttatgag acgggtggag aatggttaag
     2101 ccaactgatt ccttatctag aaaaaaatgt tcaaacagtt aatcagtttt ttgaacagta
     2161 tcttccgaaa gtgagaataa tgaaccctga aggaacttac ttaatgtggt tagattttac
     2221 cgcctatatt tcagacgacc aagaattgga gaacactctt gttcggaaag gaaaagtcgt
     2281 attaaatcct ggcatcacgt ttggtccttc cggtcatggg catatgcgct tgaatattgc
     2341 ttgtccagaa gaaactttac tggaaggact taatcgaatc aagtatgctt tagagacaat
     2401 cgattaaatc atttattcaa aataaaagga cgagacctta ctaggtttcg tcctttttca
     2461 taattactcc gtaccatacc aaactattct gaaatttcaa ttgtttcaat cactacatca
     2521 tgtacaggtc ggtcttgtgg accacgttgt acatttgcga tttcatctac tgtgtccatc
     2581 ccttctagta catgtccaaa gactgtatgt cggaaatcta gccaaggagt tccgccacct
     2641 ttatacgctt caatgatttc tgatgggaat ccagcacctt ctagttgtcc aagcatatta
     2701 gctggcacat ttgtgttatt tacaataaag aattggcttc cgtttgtgtt tggacctgaa
     2761 tttgccatag ataaagctcc gcgaaggttg aacagttcac gactgaattc atcttcaaaa
     2821 ctttcgccat aaatactttc gccacccatt cctgttccag ttggatcgcc gccttggatc
     2881 atgaaatcag gaataacgcg gtgaaaaatc acgccatcat aataaccttt tttggaaagt
     2941 tcaatgaaat tttgaaccgt cttcggtgct agttcaggga ataattgaac agtaatgtca
     3001 ccacggtttg ttttgataac agcttttggt cctttttcac tttttaaatc tagttgtggg
     3061 aatgccatat
//
LOCUS       DADVXM010000136         3050 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.143, whole genome shotgun sequence.
ACCESSION   DADVXM010000136 DADVXM010000000
VERSION     DADVXM010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.143"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            195..1652
                     /locus_tag="KB927_002579"
     CDS             195..1652
                     /locus_tag="KB927_002579"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HBB6841453.1"
                     /translation="MKKNQPNVVLIVVDQMRADALSLNSQDKIISTPTLDMMASQGYN
                     FENCYSPVPSCVPARAALLTGLDQETSGRVGYEDEVPWNFKNTLPEVFKEQGYQTECI
                     GKMHVYPSRKRLGFDHVLLHDGYLHVDRKYDKSYGEQFEYSSDYLMFLKESLGSDADL
                     IDDGLNCNSWEARPWMYPEKFHPTNWVVSEGINFLRRKDPTVPFFLKLSFEKPHAPLN
                     PPKYYFDMYMDRLPDTLDLHIGNWEKLEHVVPDVCALRGKLKEDDQRRMLAGYYGLIS
                     HIDHQINRFLMALKEFRHDKDTIIWFISDHGDQLGEHYLFRKGYPYQGSIRIPSFIYD
                     PGDLISAKKHGIKELVKIQDIFPSLVDLVLGQYVNTDGKSVKQLLFGNCEGWRREIHG
                     EHSLGLDSSQYILTEKWKFIWFPVKNTYQLFDMINDPNEMKNLYYDKKYESIIYEMKH
                     KLVGYLKGREEGFVKNGQLIQIGISNIVSTLKSKK"
BASE COUNT         1080 a          394 c          540 g         1036 t
ORIGIN      
        1 aaaattaaag atattttgat atcaaggttt attttagtat aaagtattcg tgactaatca
       61 atcatacgct ataaagtttg gtaatccatt tatatttctt gttatcacaa aaaatatatt
      121 ctttcaaaag gaaatatcaa tttcttaaat caagagagat tatttggata ttttgaatga
      181 ttggagtttt taatatgaaa aagaatcaac ccaatgttgt tttaattgta gtagatcaga
      241 tgagagcaga tgcgttatct ttgaatagcc aagataaaat cattagtacg cctacattag
      301 atatgatggc tagtcaagga tataattttg agaattgtta ttcgcctgtt ccaagttgtg
      361 ttccagcaag agcagcgtta ttaacaggat tagatcaaga aacttcggga agagtgggtt
      421 atgaagatga ggttccatgg aattttaaaa atactcttcc agaagttttt aaagaacagg
      481 gatatcaaac tgagtgtatt gggaaaatgc atgtgtatcc ttcaagaaaa cggttgggat
      541 ttgatcatgt actattgcat gacgggtatc ttcatgttga tcgaaaatat gacaaatctt
      601 atggagagca gtttgaatat tctagtgatt acttaatgtt tctaaaagaa tcattgggct
      661 cagatgcaga tttgattgat gatgggttaa attgtaattc atgggaagca cgaccatgga
      721 tgtatcctga aaaatttcat ccaacaaatt gggtggtttc agaaggaata aactttttaa
      781 ggcggaaaga tcctacagta ccatttttct taaaattatc atttgagaaa cctcatgctc
      841 ctttgaatcc accaaaatat tattttgata tgtatatgga tagattacca gacactctag
      901 atttgcatat tggtaattgg gagaaattag aacatgttgt tccagatgtt tgtgccttaa
      961 gaggaaaatt aaaagaggat gatcaaagaa gaatgcttgc tggatactat ggccttattt
     1021 ctcatataga tcatcagatc aatcgctttt taatggcttt aaaagaattt agacatgata
     1081 aagatacaat catttggttc atttcagatc atggagatca attaggagaa cattacttat
     1141 tcagaaaagg gtatccttac caagggagta ttcgtatccc gtcgtttatt tacgatcctg
     1201 gtgatctgat ctcagcaaaa aaacatggaa ttaaagagct tgtaaaaata caggatatat
     1261 ttccttcatt agttgattta gtattaggac aatatgtaaa tacagatgga aaaagtgtta
     1321 aacagttgct ctttggaaac tgtgaaggat ggcggcgaga aattcatgga gaacatagtt
     1381 tagggctgga ttctagtcaa tatatattaa cggagaaatg gaaatttata tggtttcccg
     1441 taaaaaatac gtatcaatta tttgatatga taaatgatcc aaatgagatg aaaaacctat
     1501 attatgataa aaaatacgaa tctattattt atgaaatgaa acataaatta gtaggatatt
     1561 taaaaggtag agaagagggg tttgtcaaaa acggacagtt aattcaaata ggaatttcaa
     1621 atatcgtttc aactttaaaa agtaaaaaat aaactaaaag tgaagatgca ataaaaaatc
     1681 aacatagggt atactgagtc aaaatatact cagatacagg caaaactttg cgtctttatt
     1741 tatttcaaaa aaatcaaata ttcggatggt aacaaacata ctactttgtt tgggataaaa
     1801 tcagatctga gtcagagtaa gttcattctg attcagtttt ttatgtctaa cgacgataaa
     1861 agtttagcac atacaagatg gaattgtaag tatcccatag tctttacccc ggagtatcga
     1921 tgaaaagtga tttatggaaa attaagagta agtaactgtt ggtgatagta tcaccccaaa
     1981 ttagtatttc cagttttatg agctatttat taaataaatt ctatacggga tttgaagatc
     2041 ctgaaggtga aatcgtcatt tatcagaata aataaatcaa atagtaaaag ttcaaagaat
     2101 gaggggaaca ttagttttta ttgcttagtt taatcccagt aacgatttct gcaagatgta
     2161 aaaggtcttt catttcataa gttttcagaa gcaagttcat acgcactaac tcactttcga
     2221 ttgagtagca atcgtcaaca aactttacta tcagctgtta tttttattct ttcgcgttat
     2281 ctaaatacca tcaatttata agttgtaggt gtatttaata aaagaacaaa taactttagt
     2341 atttttatta atctaactta caaactagta gtatagggta tagtaaaaat atgataaaat
     2401 aaatagtcgt tatcttaatc caactatata gaaaatttac gttttctata tagttggatg
     2461 tttacaagtt atatctggtt taataagttt ttttctgtta gtcatggcat gttttattgt
     2521 gctggttcat caatatattg aaatgtacta aaatgaaatt ttcagttatg gtataatatt
     2581 tatgctgtct gctaccccgg cctattatgg caaggggagg aggttgtatt atgaattacc
     2641 ttttcgatat gttttttgca atcttagcag aagtatccgc gcattacatc tgtaaatggc
     2701 ttgattgcaa aattattgcc aaaaaagaca gtaagcctac ccgttaatct gaatagaacg
     2761 taaaagaaaa ccactagccc gccagctagt ggtttttggt gtatcatgaa ttaccttttc
     2821 gttaaaacaa ttataccata tttcctaaaa aatacaatta atagacgaat tatcattacc
     2881 actttgatga aaaaagctga cataaatttt tcttttattt ttataatgaa taaacattta
     2941 tcaataagct tttgaaaggc aggatcgtac tttgttgatg attgagatat tgctacatca
     3001 atctcagcag ttaagatttt tttgaattgt tgcttgaatt ttttctttat
//
LOCUS       DADVXM010000137         3014 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.144, whole genome shotgun sequence.
ACCESSION   DADVXM010000137 DADVXM010000000
VERSION     DADVXM010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.144"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..227
                     /locus_tag="KB927_002580"
     CDS             <1..227
                     /locus_tag="KB927_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HBB6841454.1"
                     /translation="KTTEFDILHALMSTPNKVFSRSDLIEKVKGIEFDGLDRSIDSHI
                     KNLRHKIENDAKSPMYILTVHGTGYRFGGH"
     gene            227..574
                     /locus_tag="KB927_002581"
     CDS             227..574
                     /locus_tag="KB927_002581"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841455.1"
                     /translation="MRKRTIKTQLAVSFLAIATLIIGSISLVALSLMNNHFSKYVEER
                     QEDLLNQYVYTIDLLWLNSGETWNSEELAALSEKVLENNIYFSIEDEQGNMVWELTGK
                     DLKSAQEKLKKMH"
     gene            571..1620
                     /locus_tag="KB927_002582"
     CDS             571..1620
                     /locus_tag="KB927_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6841456.1"
                     /translation="MKVSEKNSVKLDETIEVKKKLINDGNEFGKVTFYYFGPFAYTEH
                     DALFISSMKQSLMYVAIAALLVSFILASWISARLGLPLKHVSDFTHKLTRGEYADKIP
                     QETSIIEINSLIDSLNDLSNQLEKQHGLRKRLTTDISHELRTPLATLKGNVEGMIDGV
                     WKITPERLQSCYDEIDRLTRLIGNIEIINKIEAKYDHLNKTEFNIYKLIESVIENFAS
                     KIESKNLHVEIQGDNINISADKDKMNQVVINLLNNAIKFTQKEGTIKFSISKNKDHVL
                     LIVEDNGIGIEKDQQLHIFDRFYMADPSRSRALGGQGIGLAIVKSVIEAHKGSITVKS
                     KLGLGTKFVIKLPFQ"
     gene            1635..1841
                     /locus_tag="KB927_002583"
     CDS             1635..1841
                     /locus_tag="KB927_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841457.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            1862..2458
                     /locus_tag="KB927_002584"
     CDS             1862..2458
                     /locus_tag="KB927_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HBB6841458.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
BASE COUNT         1099 a          405 c          589 g          921 t
ORIGIN      
        1 ttaaaacaac tgaatttgat attctacacg ctctaatgtc cacacctaat aaagtctttt
       61 ctcgtagtga tttgatagag aaagttaagg gaatagaatt tgatggacta gataggagca
      121 tcgattctca tataaaaaac ttaagacata aaattgagaa tgatgctaaa tcacctatgt
      181 atattttgac agtccatggt acaggataca gatttggtgg ccactaatga gaaaaagaac
      241 gataaaaact caattagctg tttccttttt agcaatcgca acattaataa taggatcgat
      301 tagtttagtc gcattaagtt tgatgaacaa tcattttagt aaatacgtgg aagagcggca
      361 agaagatttg ttgaatcagt atgtatatac aattgattta ttgtggttaa atagtgggga
      421 aacatggaat agtgaagaac ttgcagcact atctgagaaa gtattagaga ataatattta
      481 tttttctata gaagacgaac aaggcaacat ggtttgggaa cttactggaa aagatttgaa
      541 gtcagcacag gagaaactga aaaaaatgca ttgaaagttt ctgagaaaaa cagtgtgaaa
      601 ctagacgaaa caatagaagt gaaaaagaag ttaattaatg atggaaacga gtttggaaaa
      661 gtaacgtttt attatttcgg accttttgct tatacagagc acgatgcctt gtttatctcc
      721 agtatgaaac aaagtttaat gtatgttgca attgcagctc ttcttgtatc attcatactt
      781 gcttcgtgga tctctgctag attaggattg ccactaaagc atgtaagcga ttttacacat
      841 aaattaactc gtggggaata tgctgataaa atcccacaag aaacttcaat tattgaaata
      901 aattccttaa ttgattccct aaatgattta agtaatcagt tggagaaaca gcatgggctt
      961 cgaaaaagat taactaccga tatttcacat gaattaagaa ctccattagc tacgcttaaa
     1021 ggcaatgtgg aaggaatgat tgacggagtc tggaaaataa ctcccgagcg cctacaatct
     1081 tgttatgacg aaatagatcg tctaactcgt ttaattggaa atatagaaat aatcaacaaa
     1141 attgaagcaa aatatgatca tttaaataaa actgagttta acatatataa gttgattgaa
     1201 tccgttattg aaaatttcgc cagcaaaatt gagtcaaaaa accttcatgt tgaaatccaa
     1261 ggggataaca tcaatatatc tgcagataaa gataaaatga accaagttgt tatcaatctt
     1321 ttgaataatg ctattaaatt tacgcaaaag gagggaacca ttaagttttc tataagtaaa
     1381 aataaagacc atgttctttt aattgttgaa gacaacggca tcggtataga aaaagatcag
     1441 caacttcata tttttgatag attttatatg gctgacccct ccagaagtag agctttaggg
     1501 gggcaaggta tcggattagc tattgtaaag agcgttattg aagcgcataa aggtagtata
     1561 actgtaaaaa gtaaattagg tctaggaact aaatttgtta taaagttacc atttcaataa
     1621 aggaggagag ttatttgttt caaaaacaga taaaaattgc taaactagta tgtgaatgtt
     1681 gggcaaaaaa aatatttttt caactgattt cgatagatag tgtcgaaaaa gttcatttag
     1741 atatcttatc aaattctgta gtaatctttt ctaagaagga cttatcaata gctacaatta
     1801 aaaaagaagt ttttggatta caaatttatg agatgaccta aatgtgatta attaaaggag
     1861 gatgaagaca gtgaaaaaga tgacaaaatt agtatttgca agtcttggaa ttattgtatt
     1921 tttaggagcg tgtagcaatc aaagtgaatc gaataattct aatagcacaa acgaggaatc
     1981 gacttctaca gcgtctagtg aaatgaatag tatggaggga atgaatcacg aaggtatggt
     2041 tccttcttca atgaaagatg ctgcgaaccc taaattcccg gtgggaagta atgttatact
     2101 gctaggcgat catatggaag ggatgaaagg tgcaaatgct caagttgtag gggcctttga
     2161 tactacaatg tatgaagtaa gctatgagcc aaaaactggg ggaccaatgg ttaacaatca
     2221 tcgatgggta gtacaagaag agttaaaaga tactgagact gtagcaaatg agggcgatac
     2281 tgttatcttg aatgccgatc acatggatgg gatgatggga gctgaagcaa aagtagataa
     2341 atctattaca ggaactgttt acgttgttaa ttacactcca accgatggtc aagaagaagt
     2401 taagaatcat atgtgggtaa ctgaagatga gatggaatat gacgaaaata atgagtaatt
     2461 ttatatacta aaccaacaag ctggtacatg gtcttcgtat tctcaacatg aggaatatga
     2521 gctctttgtt aataaggact gatgagttgt gcaaaatcaa atctgggtca gaacgaacct
     2581 cattctggct cagatttttg gctcttcgac atttagtgct ggtagagaga caactgaaaa
     2641 tttagtcata accagttagg cagagtgctt aactggtttt tgttcgcatt tattattctt
     2701 ttgatattgg ctgcttgccc ttcaatttta tttggtttct taatcaactc ttcatataac
     2761 cccaaatcat atattaatga ggtgcctcct attcctataa atctatctct tctttaatag
     2821 tatgagaaaa gtctactctt gtagatttaa attgtcaaca aaaaatttac agatgtaaat
     2881 gataagttga atagagaaag ataaattatt tttttggtat tcatataagg ttaattatgt
     2941 attatcacaa aatgattgtt gtcgaataac taaaagtgtc aaaacaatga tgaaatcatt
     3001 tagttcttat aaat
//
LOCUS       DADVXM010000138         2990 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.145, whole genome shotgun sequence.
ACCESSION   DADVXM010000138 DADVXM010000000
VERSION     DADVXM010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2990
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.145"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            540..1499
                     /locus_tag="KB927_002585"
     CDS             540..1499
                     /locus_tag="KB927_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6841459.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYCF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(1486..2091)
                     /locus_tag="KB927_002586"
     CDS             complement(1486..2091)
                     /locus_tag="KB927_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841460.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
     gene            complement(2331..>2990)
                     /locus_tag="KB927_002587"
     CDS             complement(2331..>2990)
                     /locus_tag="KB927_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6841461.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSTGQKFDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSNCGHKDGKKSLEIRKWTCPICHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          974 a          501 c          467 g         1048 t
ORIGIN      
        1 tctattatta gatatgaaaa tcgcatttag ataaaataga aaaatatgaa tatattttaa
       61 atattaagat gagagtcatt aacttatgat agtagtcaat ttgcttttca ctaattacaa
      121 aatatgtgat ataggaagtt tagttattgt tctcataatg ccatcctgtt tttagattat
      181 ctagtaattt ttttgttatt taaaattagg agcagtgcca attgttttaa ttttaaaggc
      241 tttttttata tcttctaaat tagaagatat ttgtatatca atatggaata tattaccttt
      301 tttgtatttt tttatgttat ctttagctaa aacatcaaat acatgtcctt gaaattgtat
      361 cgaggcagct ggatttagtt taaattgagg aaactttacc acagctgatt caaaacactt
      421 gtcacatttt tttatttttt taccttcgcc gattgtaaaa ttaagctaga caactaaaaa
      481 agtcatttgt gctacactca aaatagttcc gtcgaaagaa ttataaggag tgagtacaaa
      541 tgacctatac ccatcttaca ccaactgaac tcgtaatgat agaagcttat ttcaatcaat
      601 cacactctgt ttcaaaagta gcccatctgg tacaacgttc tcgacaaacc atttataatg
      661 tctattgttt tcttaaatct ggtggaagcg caataagcta ctatgaacaa tataagaaaa
      721 acaaacgtaa ctgcggaaga cgtccgattg tgttaccaga tgggcaacaa gaatacattc
      781 aaaaaaaggt ggctcaaggg tggactccag atgtccttat tggtcgagca gagtttccta
      841 ttgcttgttc ggtacgtaca ctatatcgga tgtttaaaga taaaaccttt gaccctcacg
      901 atttaccaat gaaagggaaa agaaaaccaa acggacataa agaaaaaaga ggaaaacaag
      961 cttttcgccg ttcgattcag gatagaacaa ctgattatat acagttcaat catgagtttg
     1021 gtcacctaga aggtgacacc attgtcggtg gaaaacataa aagtgcggtg atcacgttag
     1081 ttgagcgatt atctaaagtg atcatcacct tgaaacccgc tggtaggcaa gctatagata
     1141 ttgagaatag actgaatcaa tggtttcaat ctgtaccgaa acacttgttt aaatccatca
     1201 catttgattg tggaaaagag ttctcgaatt ggaaaaagat tagtaatacc aatgatattt
     1261 cgatttattt cgctgatcca ggaacacctt ctcaacgagg actaaatgaa cattcgaatg
     1321 gcttattacg taaagatggc ttatataaag ctatggattt taataaggta tccgaaacct
     1381 ttatccaatc ggtggcatca aaacgaaatc atattcctag aaaatcatta cactatcgca
     1441 caccattgga agtatttttg agttacgtag gtaaagatga tttgtctagc ttaatttgac
     1501 aaacgaaact ttgtaaaaat attcgattga atattctatt tggcacgact cacttggcag
     1561 tatatgtatg tcaatatttt tcatctgttt cataggtatt tcaaaatcta aactattaaa
     1621 aacatataat tccctgtaat tatttacatc taactctact aaatttatct ttggaacaat
     1681 agatcctcca cccattccac cataataaaa aaaatcttgt tctctatcaa aatagcacat
     1741 attaagctca gtttgtttat catcctcaat aattttataa atcaaaccta tataatcatg
     1801 aatgctggca aaaatttttt ttaagtcaag ttctaaatct tcttcgaaaa cacatttaat
     1861 ttctcctact gataattgat actctatatt acatgactta attagttttt tagatccccc
     1921 ctccagatag gcatatgttt caataattat gttcttttta ttgcttggca aatttccgtt
     1981 atttattgca taaattaaaa atgactgtct atttagccca taatctaata caacttcttc
     2041 atactcatat ttctttaaat atttaatatg aaaatatgct gaattaatca aaactcgagt
     2101 gttactgttg ttatttattg ttgttctatt gtgtataaaa ttgtataggt tgtcatattt
     2161 tcttggttta gtgaactact caccacttag ctaaacctaa cggtttctta cgtttgaagt
     2221 gggagcttct tgggaagaga gcatacttga tagcgtatta ctttactaac agaggtgcct
     2281 cttatttacc aagctatccc cgtagttcct acggttcttg tttatttgat ctaagccaat
     2341 cccatagagt gtagccttag accttcggtc aggatattga tactagcgtt gatatctcgg
     2401 tcatgatgag tatgacaaat agggcaagtc cattttcgaa tttcgagaga tttcttgccg
     2461 tctttatgtc cacaattcga acagatttgg ctagatggaa accacttatc tactttgatg
     2521 attttccgac cgtaccagtc agccttgtat tgtaatttag acacaaaact agaccaagaa
     2581 acatccgaaa tactttttgc tagtttatga ttacgcaaca tgccttttgt gtttaagtct
     2641 tcaatacaga tgatatcgtg atttttgata atttctgtac tcaacttatt cagaaaatca
     2701 gtacgttgat tcattacttt ttcatgcaat cgtgctactt tacgtttttg tgtttgataa
     2761 tttctagctt caaacagatt gatacctttt tgtttagcta ataaggcacg tcttgacaac
     2821 ttacgttgtt cacgtttgag tttcttttcc attttggacg taaatttatt attatcaaat
     2881 ttttgaccgg tagaaagaat tgcaaagtct ataataccta ggtcaatacc aacagcagaa
     2941 ttagatttag gtagttcgcg aacttcttct ttgcataaca aagaaatata
//
LOCUS       DADVXM010000139         2610 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.146, whole genome shotgun sequence.
ACCESSION   DADVXM010000139 DADVXM010000000
VERSION     DADVXM010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.146"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(313..903)
                     /locus_tag="KB927_002588"
     CDS             complement(313..903)
                     /locus_tag="KB927_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBB6841462.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
     gene            1426..1587
                     /locus_tag="KB927_002589"
     CDS             1426..1587
                     /locus_tag="KB927_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6841463.1"
                     /translation="MEPKDKYLDYARVNKDKFIETIIKGKIPDDEKDAVFMAGSPGAG
                     KTEVALGLA"
     gene            1606..2100
                     /locus_tag="KB927_002590"
     CDS             1606..2100
                     /locus_tag="KB927_002590"
                     /inference="COORDINATES: protein motif:HMM:NF018154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6841464.1"
                     /translation="MIDADYFRAQFPEYNGKNSSVFQKASSWLVEQSLKYVLEHGYSF
                     ILEDTFAILSAEKNIIRALKNNFRVTIFYVYQDPKVAWDFTRKRELAEGRHVPKEMFI
                     NAFFKSRENIEKVKNRHPEVVLHIMIKDYQNDISEVHYAADNIQLVLPIQYTSKELEE
                     ELHD"
     gene            2093..2254
                     /locus_tag="KB927_002591"
     CDS             2093..2254
                     /locus_tag="KB927_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841465.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
BASE COUNT          926 a          409 c          447 g          828 t
ORIGIN      
        1 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
       61 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggaggc tcattgtcaa
      121 ggacaatcgg aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac
      181 tgttgccatt ccatctatga atataaatag agtgtatctt ctttgataaa tgtcagaaaa
      241 agtgtgacaa ataaccatca gtaaaattac ttgtcatact attgataagg agtatttaat
      301 tgaagagaat gattaggaga aaggatctcc gtacttttta tagtaatcat agaatccaag
      361 tttgtataga cgaatctttt tttctcttat ttcttctgtt tcaaaatgga ctgcttgaag
      421 aatcaagtct gtgaattcta taggagctgt tccattcgca gtaatcaaat tacgatcttt
      481 cacagcttgt tgttctataa aatcttcttt attctgataa ttttccgatt ctaaccaagg
      541 aaattgcgca tttccggtgt gtttgtaacc ttgcaataat ccgctctgag ctaaataatc
      601 aactgcccca caaatagcag ctactggtac gtctgttttt aacaatttat cgattatttg
      661 atataaatga tgatttttta tgtcccatga attgccaccg atcataataa aaaggtcaac
      721 tttttcaggt atttgttcga ttaagtaatc gatttttgtt tttaatcctc caatggaagt
      781 gacctctgat tggatagaag cagttttgtt ttgccatccc tctttttggt ttagtgtgct
      841 agtaatataa gcaccttccc aatcggcata ttcctctaat agaaacgtaa tcgcagtttt
      901 cattttcaag ctctccttta ctatctatga caaggacaac agttttaaca tacagacatt
      961 cattaaattt ggatagcgac agcgaaaaca acaattctta agttttagac agagtataca
     1021 gacagtcaac ttaattaaat acgaactaaa taaaaatgac aggtaatcat ttttgtttac
     1081 cagcattata acattttgca tacatggatg acaaaagaac caattcccac ttgcttgagt
     1141 acaatcttaa aagaaactgg aaggcaaaaa gtaattatag aaacgaaaaa taaatcatat
     1201 cgggcactca gacatgaaaa caaccctaga aatatataac tagtccaatg aaaaaaaagc
     1261 gaatgccgta gaaaacaagg attctgcgta cattcatatc tcattttgcg agcatatctg
     1321 ctattactgt gactaaatgt taatatggtt aaaatgaccg ttatattttt tatataaata
     1381 tcgtataatt agtatgaata tagaagaagg aaagaaggtg caatcttgga acctaaagac
     1441 aagtatttag attacgctag ggtcaataaa gataaattta ttgaaacaat catcaaggga
     1501 aaaatccctg atgatgaaaa agatgcggta ttcatggctg gaagcccagg agcaggtaaa
     1561 acagaggttg cactaggttt agcttaaaat tatgacaacc atgttgtgat tgatgcggac
     1621 tattttagag cacaatttcc agaatacaat ggaaagaact caagtgtttt tcagaaagct
     1681 tcttcttggt tagttgaaca atcattaaaa tatgtactgg aacatggcta ttctttcata
     1741 ctagaggata cttttgctat ccttagtgca gagaaaaata ttattcgagc ccttaaaaat
     1801 aactttcgcg ttacgatttt ctatgtttac caagatccca aagttgcctg ggatttcact
     1861 cgaaaacgtg aactagctga aggacgtcat gtgccaaaag aaatgtttat caatgcgttt
     1921 tttaagtcca gagagaatat tgaaaaagtc aaaaatagac atcctgaagt agtccttcac
     1981 ataatgatta aggattatca aaacgacatt tctgaagtgc attatgcagc agataatatt
     2041 caattagtac taccaataca atatacttca aaagagttgg aggaggaatt acatgactga
     2101 gaaagaacaa gtacaacaaa tcgtgaagaa gtataataaa agtatcgctg atttatcaga
     2161 aaacgcctca gcgaaagaat ttaaaacagt aatgaattac gtagcagatg aagcaaatcg
     2221 taagcagcga aaactagttg ggttggataa ataaattttt taaaccatat ccttgtaaag
     2281 ttgagttttt tattttaatg aattaagact attaaataga taattattgt aacttaaaaa
     2341 acacagctaa aaattagttg tgttttttat taggtttact tttctggtat aaaaggaact
     2401 agctactttt tcaaaatttc taaatcattc aatatgtagc gcttactaaa ttattcgcca
     2461 taaaatttta taattggatc actcattgtt ttacctaagt catatttaag taataaccgg
     2521 tgtttttaca taagaagact tcgggtattt tttagtttga ttagctctga tatacctata
     2581 aagaatatgc taaggtaaga atagtaaaaa
//
LOCUS       DADVXM010000140         2607 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.147, whole genome shotgun sequence.
ACCESSION   DADVXM010000140 DADVXM010000000
VERSION     DADVXM010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.147"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..182)
                     /locus_tag="KB927_002592"
     CDS             complement(<1..182)
                     /locus_tag="KB927_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6841466.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="KB927_002593"
     CDS             517..951
                     /locus_tag="KB927_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6841467.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="KB927_002594"
     CDS             974..1294
                     /locus_tag="KB927_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841468.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="KB927_002595"
     CDS             1435..1626
                     /locus_tag="KB927_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841469.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="KB927_002596"
     CDS             complement(1697..1954)
                     /locus_tag="KB927_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBB6841470.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="KB927_002597"
     CDS             2112..2375
                     /locus_tag="KB927_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841471.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="KB927_002598"
     CDS             2399..2587
                     /locus_tag="KB927_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841472.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
BASE COUNT          999 a          371 c          536 g          701 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaaga
//
LOCUS       DADVXM010000141         2484 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.150, whole genome shotgun sequence.
ACCESSION   DADVXM010000141 DADVXM010000000
VERSION     DADVXM010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.150"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(1014..1304)
                     /locus_tag="KB927_002599"
     CDS             complement(1014..1304)
                     /locus_tag="KB927_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841473.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2204)
                     /locus_tag="KB927_002600"
     CDS             complement(1512..2204)
                     /locus_tag="KB927_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6841474.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          734 a          458 c          349 g          943 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgagtttc tacatttgtt
     1681 ttttcttgtg tcagtgttgc gatttgttga ttcaaaccat ttacagtatt ttgtaattct
     1741 gaaagttttg cttgtgcttc ttgtagtctt gctgtccaat ctgcattcag atgattgatt
     1801 tcatcatttt tttggttgat ctcatctagt ttgacattga tttcattttg tttgctttgt
     1861 agttgtgcat ccttgctgac taattgactt tctaagtttt gtttttctgc tgccgattga
     1921 tttttttggt tttctaattc atttactttt gtttggtatt cttggacatc tgcctttgaa
     1981 tcttgcaatg tctgttcttt ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct
     2041 ttatctgtca atgtatgatc aagctgtgtc agattctcat tgattgtatc aatatctgtc
     2101 tctccacccc acaaaataat ttcatttgcg taccgcgtgc ctgtgtagcc aattagacat
     2161 agaaatgcaa cgacaatccc accagtaata aatttctttt tcatttgcat agctccttaa
     2221 tccaatactt ttacatgcta aaagtaagtg atctcaaaca caatgtcaag cgtttttaaa
     2281 ttacatatgt aattttaata taaatactat caaatactca tttaatcctc cttttttatc
     2341 tatttaaaaa atctttttta tagagaaaaa tgcaggttaa tactttctta aataaatatt
     2401 tatggtgaac aaaaacaaaa aagcaagttt tattaaacgt aacccttttc atttcataga
     2461 ttactgtatt tattacaaaa aacg
//
LOCUS       DADVXM010000142         2459 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.151, whole genome shotgun sequence.
ACCESSION   DADVXM010000142 DADVXM010000000
VERSION     DADVXM010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.151"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            142..924
                     /locus_tag="KB927_002601"
     CDS             142..924
                     /locus_tag="KB927_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841475.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDPKKVGRKIRSIRK
                     KLGLTMQEFGYEVSNSPRSTVSTWEHGGNLPNKAKLKKIADIANCSVEDLLFDEGFIS
                     EKSQVKLINELKEENSKLKEKIKYYECLFDGIESLLNSRKNS"
     gene            964..1575
                     /locus_tag="KB927_002602"
     CDS             964..1575
                     /locus_tag="KB927_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6841476.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
     gene            2019..2168
                     /locus_tag="KB927_002603"
     CDS             2019..2168
                     /locus_tag="KB927_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841477.1"
                     /translation="MKLEIKEVVCDWGIYVDGETYPFMIFNSKANAQEIMRIMELDNK
                     HERFD"
BASE COUNT          984 a          298 c          466 g          711 t
ORIGIN      
        1 aagacattca agaaaaatat agtgatacgt tttcgttaga taaagactat gaattattgg
       61 attctataat aaaaaatata tttacaaaat attactcaaa agaatttgaa gtaacccaaa
      121 ttccataaga gaggtgattg tatgaagcca aatccttcag aagcaggaaa acgaatcaaa
      181 caattacgcc tttcatgtgg ttttactatg gaagaacttg gaaggaaaat agataattca
      241 ccacgtgcga ccatatccaa ctgggaacgt gggaccaatt taccaaatcc acaaaagctg
      301 aaattattat caactatcac taattcaaca attgactgga ttaaatgggg aactttagaa
      361 gaatatataa cttcatacct tatcgatata gggtatgagc tatatattaa ggactttcca
      421 gaaatacctc acaaagtctt taaagacatt caagaaagat atagtaatac gttttcgcta
      481 aataaagact atgagttatt gaatcctata ataaaaaata tatttacaaa atattactca
      541 aaagattttg aagattatcg agacatagaa gttaaaccag accctaaaaa ggtagggaga
      601 aaaattcgtt ctattagaaa aaaattagga cttactatgc aggaatttgg gtacgaggtt
      661 tctaattctc ctagaagcac tgtgtcaaca tgggaacatg gtggtaactt accgaacaaa
      721 gccaaactaa aaaaaattgc agacattgcg aattgtagtg tagaagattt gctttttgat
      781 gaaggcttta tttctgaaaa atcccaagtt aaattgataa atgaactcaa agaagaaaat
      841 tcaaagctaa aagaaaaaat aaaatactat gaatgtttat ttgatggtat agagagtctg
      901 ctgaactcac gaaaaaattc ctagttaatt aaactagagt aaaattattt gtaggtgtta
      961 aatatgttag ttggctatgc acgagtcagt tcagatgatc aaaatttgga aagacagctt
     1021 gaagaattta gaaaaattgg tgtcgaaaaa gtatttgctg agaaaaaatc tggacgtaac
     1081 acagtagaac ggccagagtt caataaaatg ttgtcatttg tcagagaagg ggatacgctt
     1141 gtttttgagt cgcttgaacg cttaggaaga aattctgatg aaatactaga aacagtatct
     1201 tttatagata aaaatggtat gggcttaatg gttttgaatt taccaatttt agatacaaaa
     1261 tttggtgatc caaacttaga aaaacttgtt agaagcttag taattaacat tttttcttgg
     1321 acggctcaaa atgagaggga ggaaattaag agaaaacaaa aacaaggaat agcaattgcg
     1381 aagaagaaag gagtctataa aggaaaaccc tacgaatatt cttctactgc aaagaatcca
     1441 caaaagaggt ttatctataa tgaaatagta agaatgcttg gagaaggtgt tccgattaag
     1501 cgaattgcag aaaaaacagg aacaaataga aatttagtct atagaataaa gaaaagaata
     1561 agtgaatctg attgatttta agttctttga gaaatcaatg ttacgagaga aggattctaa
     1621 gcctgtttca aacttttaag gtgtacaatt atacaaagaa gcttctaaac aaaagaatta
     1681 attttgtggc agtcaagtaa cgacagaaat agaaaagaaa gaggctatgc gagagtgaat
     1741 caacaagtta attgggttaa tgattttgaa aaagaatttc gactgaaatt ttttggaaat
     1801 cctacagcag aaagtacaga agaaaaaaat tatgactggt cagaatttta ggttgcatat
     1861 tcgattcaat aagtgttgaa gataatagtt ctcttacgcc acagtataca acgttagaat
     1921 atgacgaaaa cagattcaat acatttcctt gcaataccat tcaagaatca attgataagc
     1981 atgagtgata attgattatc tacaggaagg tgttttttat gaaactagag atcaaagaag
     2041 ttgtctgcga ttggggaatt tatgtagacg gagaaacata tccatttatg atttttaata
     2101 gtaaagcaaa tgcacaagag ataatgcgta tcatggagtt ggataataag cacgaaagat
     2161 ttgattaagt aaaaaaaatg gagaatgaat gtgaagcagt ggaataccaa aaaacatgcg
     2221 ccaataataa gtatatttta ggtgcaatgg gattaggtaa atcagcttct attaaacagg
     2281 tctacgaaga atcacaggag aattgcgtat atgaaaattc gaattaaaga gtgagaatat
     2341 gtgggagcta atttatttag ttttatactt aataggaaaa tcaactgaat ttgtatataa
     2401 caataaggta atatttatat tgttcttaat agtttgtatt atcgtatttg atgtctatg
//
LOCUS       DADVXM010000143         2450 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.152, whole genome shotgun sequence.
ACCESSION   DADVXM010000143 DADVXM010000000
VERSION     DADVXM010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.152"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            78..1517
                     /locus_tag="KB927_002604"
     CDS             78..1517
                     /locus_tag="KB927_002604"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBB6841478.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            1519..>2450
                     /locus_tag="KB927_002605"
     CDS             1519..>2450
                     /locus_tag="KB927_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6841479.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILP"
BASE COUNT          875 a          389 c          435 g          751 t
ORIGIN      
        1 ttaaattaaa tgattgattt ttcaacggaa aacgtttacc atactagttg taaaaagata
       61 aattgaagga gtaaaatatg aacttacctc gagaaatacg atatcgtgct tattctgatt
      121 ggactaaaga tgagatggat aaaattaagg ataatgtaaa acgatcacct tggcgtgcta
      181 gctatcatat cgaacctaaa acaggattgt taaacgatcc taatggtttt tcttttttta
      241 acggaaaata tacgcttttt tatcaaaatt ggccatttgg agctgctcat gggttgaaag
      301 aatgggtaca caatgaatca gatgatttag ttcattttca tgtaacagga gcagaacttc
      361 ttccagacac aaaacgagat agccacggcg cttattccgg ttctgcatat gaaatagagg
      421 ggaatctatt cttactctat acaggaaacg ttcgaaatga aaattgggaa cgtgatacac
      481 ttcaaatcgg agcatggatg gataaagact acaacattac gaaaggtgag aatgttctta
      541 ttcataaacc tgctgatgta actgatcatt ttcgtgatcc acaaatgttt aattatgaag
      601 gacaattata tgcgattgtt ggagcacaaa atttagaaaa atcaggcttt atcaaacttt
      661 acaaagcgga tgacaataac gtggaaacat gggaggaagt tggcaacctt gattttggcg
      721 gcactggttc agaatacatg attgagtgtc caaatctagt atttgtagac aaaaaacctg
      781 ttctcattta ttgtcctcaa gggttggata aatctgagct aaattatggg aatatctatc
      841 cgaatacttt taagatctgt caatcgcttg acatagagaa agtaaaactt gtgggcgctt
      901 cagaaattca aaatcttgat tatggatttg aagcgtatgc gactcaagga ttcaatactc
      961 ctgatggtcg tgctctgatt gtcagttgga ttggactacc tgatatcgat tatccaactg
     1021 ataagtatga ttatcaggga gcaatgagtc ttgtaaaaga actttcaata aaagatggta
     1081 aactttacca atatccagta gaagctatta catcattacg tgctagttct gaacaattta
     1141 cagcaaaagc agaaacaaat aatacttatg agcttgaact aacttttcct ccaaatcaga
     1201 aatcggagtt acttcttttc tctgatagta aaggaaatgg acttagcttg attgtagata
     1261 ccaaagaagg aaaaattatt ttagatcgca gcaaagcagg cattcaatat gccactgact
     1321 ttggtacgat tcgtgaatgc tcaattgata ctaaagaaac aactgctaac atttttgtag
     1381 ataactcaat cattgagatt tttattaata aaggagaaaa agtgtttact agtcgtgtat
     1441 tccctgaaaa tcaccaaaat ggtattcaaa tcaaatcagg cgaacctact ggaaaatact
     1501 ttgaattaaa atattaaaat ggtagcaaaa ttaactgatg tcgctgaatt agctggagtt
     1561 agcccaacaa ccgtttcacg cgtcattaat aataagggat atttatcaga aaaaacaaaa
     1621 caaaaagttc atgaagctat gaaaactctt ggttataaac caaataattt agcacgtgga
     1681 cttcaaggaa agtcacctca gcttattggt cttatttttc ctaatattag taatatcttt
     1741 tactctgaac tcattgagta tctcgaaatc gagttattta aacatggata taaaacgatt
     1801 atttgcaata gtcaaaatga tcctgctaaa gagagagaat acattgaaat gcttgaagcc
     1861 aaccaagttg atggcataat ctcatcaagc cataatcttg gaattgctga ttatgagcgt
     1921 gtgagagcac ctattgttgc ttttgataga aatttagctc ctaatgtttc cattgtttct
     1981 tcagataact ttgaaggggg aaaacttgca gctaagactt tacaaaaaaa tggttgtcaa
     2041 aataccatta tgattacagg aaatgataac acggattctc ccacagaatt acgtgcacta
     2101 ggtttttctt ttcaaaatcc aaatggaaaa attttcaaaa ttcctaataa tctgtctact
     2161 atccgtcgtg aaatggaaat aaagtcaact attataaatc acaaaccaga tggtattttt
     2221 gtttctgatg atttaacagc cattctcact atgaaaattg ctcatcaact taaacttaat
     2281 atcccagaag atttaaaaat tattggatac gatggtacct ctttcattga gaaatttttc
     2341 ccacaattga caacaataag acaaccaatt gatgaaattg caagtcttat tgttgatatt
     2401 cttctgaaaa aaattaaagg cgaaaagaca aataaggatt atattttacc
//
LOCUS       DADVXM010000144         2398 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.153, whole genome shotgun sequence.
ACCESSION   DADVXM010000144 DADVXM010000000
VERSION     DADVXM010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.153"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            207..2069
                     /locus_tag="KB927_002606"
     CDS             207..2069
                     /locus_tag="KB927_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6841480.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="KB927_002607"
     CDS             2069..>2398
                     /locus_tag="KB927_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6841481.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DADVXM010000145         2301 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.155, whole genome shotgun sequence.
ACCESSION   DADVXM010000145 DADVXM010000000
VERSION     DADVXM010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.155"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            138..1751
                     /locus_tag="KB927_002608"
     CDS             138..1751
                     /locus_tag="KB927_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6841482.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT          720 a          407 c          447 g          727 t
ORIGIN      
        1 aaaattttta ggttttatcc acaaattatt tctctatatt ttctgtctat tcaaaataaa
       61 caataatttt ccggcacaat tatttgctgt tttttaccat aacatagtac gatcaacgta
      121 gaaaaggaga tgtttttatg aaagttgttg tcattggcgg tgtagctggc ggtccttcat
      181 ttgccactcg tttccgtcga ttgaatgaag cgcacgaaat cattatctat gaacgcggag
      241 aaaatatttc ttatgcaagt tgtgctttgc cttattattt aggaggtgtg atcactgacc
      301 gtgactcgct gatcgaacgt acaccagaaa tattgaaaac aaaaaacaac atcgatgtct
      361 ttactaaaca cgaagtaaca gcaatcgatc cttctactaa gcgattaaca gttaaagacc
      421 tatccacaaa tgaagaaata aaaacagatt acgataagtt gatcatctct tctggtgcta
      481 gaccagatta tccggatatt cccggagttt ttgaagcaga aaacggcttt gtcctccgta
      541 gtgtgacgga tgcggatcga atcaaatcgt tccttgaaga aaaaaatcca caacatgtcg
      601 tcattcttgg tgcaggtgtt atgggtctgg aattagctga gaatttcaag catcgcggct
      661 tagacgtgac tttaatcgat caattgccac aagtcgcttt cccttatgat ccagaaattg
      721 ctaatttagt ttatgacaaa ttgctgaaag aaggattagc cgttcattta gaaacaagag
      781 ttactgagat ccgtgataaa ggtcgagaaa tagtattatc agatggctcc gtcctttctg
      841 ctgatatgct aatttttgct gttggtgttt ctccgaagaa tgaagtggtg aaagcaaccg
      901 gcatacaatt atcagataca ggtcagatca ttgttgatga ccagttacaa accaatctgc
      961 cggacatcta tgcgattggc gatattatcg aaacgactag tgtagtgact ggtcagccga
     1021 tccaaagtat gctttccagt gcggccaatc gtcaaggaca tatgctggca gatattttaa
     1081 atggtacgcc tatgcgctat cgcggatata ttggtgcagg tgtcgcaaaa atctttgatc
     1141 atacagcaag ttatgcggga atgacagaac atgaattaaa agcatcaggc ataacaaatt
     1201 ataaaactgt ttttatcact ccctttgacc atgcctattt ctatccagaa gctacaagat
     1261 taaatctaaa gctgattttt gatgcagata gcggtcgtat tttaggtgga caagcatttg
     1321 gagaaaaagg tgtcgataaa cggatgggag aactttctgt agcaatcacc ggaaacttga
     1381 cagtctttga tttgcctgat ttggagttgc cttactctcc accgtattct actacccgtg
     1441 acccgttgaa tatagctggt tatgtcgcaa tcaatcaaat gacgaatatc gtagaaacga
     1501 tcaaagcaag tgatataccc gaaaacgatt tgaaagaagc gttcttttta gatatacgtg
     1561 aacctaataa agcaccttct ggcagtatct cggcaacaaa aaatattcca atgaatgagt
     1621 tacgagatcg aatcaatgaa atcccaaaag ataaaaaagt ttacattact ttcagaagag
     1681 gattgaatac ttatacttct gcccgaatct tggcaggttt gggtatcaaa gcgattttga
     1741 ttgaagaata aaaaaacgac cgcggtgggt agccgcggtc taggagttat ttttacttga
     1801 ggagtaaaaa tgaaaaagta tatagggttg ttggttggta tgtatataga atagaagata
     1861 aatgtgaaga aattgtgcat tatttcttca catttattag gttatagttt aagaaagttt
     1921 aaacattgcg caatttaatt attttagctg tttcttttca taaaaaaaca tgttgtgact
     1981 ctgagacaaa tcatagtcca tagtgatgtc tctagagtaa ctacgcctaa tattacgagg
     2041 catcatatta atctatcagc actagtacct aaactagcat ccctttcgaa tattttttct
     2101 tatataataa agtttgcttt cactcctcta atctcaccaa atcgactggc ttgcgttgtg
     2161 tgatactagg aactgattgg tttagaacga cttttctatt gtaatcatat ttttcgccat
     2221 cctcgttgtc ttctaatcct tcaatgaatg atccctaatg tgtgtattaa ataatttaat
     2281 ttttttgttc ctatttattt a
//
LOCUS       DADVXM010000146         2278 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.156, whole genome shotgun sequence.
ACCESSION   DADVXM010000146 DADVXM010000000
VERSION     DADVXM010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.156"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            4..2142
                     /locus_tag="KB927_002609"
     CDS             4..2142
                     /locus_tag="KB927_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBB6841483.1"
                     /translation="MKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFFIIFTL
                     FVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKANQAIT
                     YTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKRLSAKE
                     KQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGVTDQEL
                     AVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLAKGYSR
                     NDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSMNAEFQ
                     SKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEITENAL
                     GTITSAFAPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRSGQVAL
                     DAVKALELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFGLGTTT
                     GIDLPNESPGISRSVDYMKKFNADNGKEWYTPGNFTDLAFGQFDTYTPIQLAQYASTV
                     ANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGFHQVVH
                     GTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDITTVNSNIVAYGPTNNPEIAISVV
                     LPNLLDEQDHMNLTIAKEIMDAYYDMFMAK"
BASE COUNT          778 a          412 c          503 g          585 t
ORIGIN      
        1 tttatgaaaa aaatattaaa tacttcttgg ttagaaaaaa taagaaaagg tgcacaagaa
       61 cctaagaaca aaacgtttcg ccggtcccat gttccttttc gcttaaattt tctttttttc
      121 attatattta cgttatttgt tgcgttgatt gctagattgg gttatttgca gatcgtgaac
      181 ggcgaagaga tggaggcgcg agtgaagtct acttctacga ttacggtcca agaaagtact
      241 cctcgcggaa tgatctacga ctccacagga aaagctttag ttacgaataa agcgaatcag
      301 gccatcacat atacgagagg aacacaagtt acggctaaag atttgcttga aatcgcaacg
      361 aagctgaact cgctgatcga tgttccggta gatgaaaatc tgacagatag agataaaaaa
      421 gatttttggc tggctgatcc caaacatttg aaagaagcca caaaaagact ttcggcaaaa
      481 gaaaagcaat tagggaacag cgaacaatat agtgcgatgg tcaataaagt cacagctgat
      541 gagattaatt taaacgagga gcaattaaaa attgctacca tctttaaacg gatgaatagt
      601 gcatatgaat taaacactgt ctatatcaaa aactctggtg ttactgatca agagttagct
      661 gttgtggcag aacgcgcttc tgaacttcca ggagtttcga ctggcacaga ctggacacga
      721 gaatataatg cagcaagttc actgaaaagt attcttggca gtgtgacgac tgaaaagcaa
      781 ggacttccag cagatgaagc agagaaatac ctagcaaaag gttattctcg gaatgaccgt
      841 gtaggacaaa gttatttgga aaaacaatat gaagatgtcc tgcaaggaac caaaacccaa
      901 tatgaagttt cccttgataa tgaaggaaat gtttcgaatc aaaaagaaat cttctctggg
      961 gaaaaaggtt ctaatttaat gttatctatg aatgcagaat tccaatcaaa agtagaagaa
     1021 attttgaaaa ggaattatca aacattgatc aacaacggca aagcacagta ttcgcctggt
     1081 gcttatgcag tggctatgaa tcctcagaca ggagaagtgc tagcaatgac tggtttcagt
     1141 catgaacaag gttccaaaga aatcaccgag aatgctttag gcacgattac tagcgccttt
     1201 gctccagggt ctgtagtcaa ggctggtact ttgacagcag gctgggcaag taacgcgatc
     1261 agcggaaatc aagttttgat tgatgagccg attcgtctac aaggtgcttc agaaaaaagc
     1321 tctgtcttta atcgaagcgg acaagttgct cttgatgcag tcaaagcatt ggaattgtct
     1381 tctaatacgt atatgatcaa agtggcgtta aagatgttag gactagacta tacacctgga
     1441 atgggactac ctagtttaga tgaagaagct aaagcttatc agcaattgag agactctttc
     1501 aaagagtttg gtcttggtac aacgactggg atcgatttgc cgaatgaatc tcctgggatc
     1561 tcacgttctg ttgattatat gaagaagttc aatgcggata atggcaaaga atggtatact
     1621 ccaggtaact ttaccgattt ggcatttgga cagtttgaca catatacacc aatccaatta
     1681 gctcaatatg cttcaactgt cgctaatggc gggaaacgag tacagccgca cctagtcaaa
     1741 gcgatctatg gcaatgacga aaatggaaac ttgggtgaag tgaagaaaga aattggcaca
     1801 acagtagaaa atacggtcaa tatttctgca gaaaatatgg cgatcctccg tgaaggattc
     1861 caccaagttg tccatggtac cgatccttac acaacagcca aaccattagc cagtgcgaaa
     1921 atggaccttt ccgcaaaaac agggactgca gaaacggttg cggaaggtca tccagatatt
     1981 acgacagtca atagtaatat cgtggcatac ggaccaacaa acaatccgga aattgccatc
     2041 agtgttgtct tgccgaactt attagacgaa caagaccaca tgaacttgac gattgctaaa
     2101 gaaataatgg acgcgtatta tgatatgttc atggcaaaat aaaaaagagg tcgtgaaaaa
     2161 gccgcttagt ttcgagtatg aagaaaaatt ttgtgaaaat agcttctcac atttttgctt
     2221 aaatttgact tcataccgag aaactggctt ttgaacaccg tttactcggc aaaaaagg
//
LOCUS       DADVXM010000147         2188 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.157, whole genome shotgun sequence.
ACCESSION   DADVXM010000147 DADVXM010000000
VERSION     DADVXM010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.157"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            65..>2188
                     /gene="acm"
                     /locus_tag="KB927_002610"
     CDS             65..>2188
                     /gene="acm"
                     /locus_tag="KB927_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBB6841484.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVT"
BASE COUNT          860 a          344 c          427 g          557 t
ORIGIN      
        1 aaaggatttt tgagagatga tatagtaggt tttattttta gttaaaatag gggagataga
       61 aaaaatgaaa aagtgtagaa atattatttt atcaatgtta tttattatta ctaatataac
      121 atcactgatt cctgttcatg tctatgcgga tgcaggcaga gatatcagca gtaatgtcac
      181 ttcgttgacc gtggacccaa cgaatattac agatggagga aacataaaag taaaattctc
      241 gtttgacgaa aaaaaacaaa atatccaacc aggtgattat ctttggatca attggccaag
      301 tgaaggaaat attcgcggtg aaggattcca aaaagaaatc ccattaatga ttgaaaataa
      361 aaatgttgga actttaacgg tcagaaaaga ttctgcgcag gttgtgttta atgaaaatat
      421 taaaaaccta gactcagtag aaggttgggg gcaatttgag atacaggcca gaaacgtaac
      481 cgataccggt gaagaaaata cgggaccatt caccgtgacg agcggtgata aaacagctac
      541 tgtaaatgtg acaaagccag cttctggttc ttcttctagc gttttttatt ataaaacagg
      601 agacatgcta cctgaagata ctaagcacat tcgatggttt ttgaatatta acaataacgg
      661 cacttatgtt gaacaaccag ttaaaatcag tgatgaaatc caaagtggac aaagattaga
      721 tccaagtacg tttgaaatta atcaaataca cttaggtgaa cagaaggttt atagaggaga
      781 agagggaatc caacaatttt tacaagattt ccccagcgct acatttaatt tttcagtaac
      841 tgataattac attgaaataa ctataccaaa aaactttgtc aatcttagga aaataatggt
      901 gagttataag acgatcatag aaaacccaga acaaataaat tttgagaatc attcggaagc
      961 ttggtttaaa gaatttaata aacctgctgt tgatggagaa agtttcaatc atacagttaa
     1021 aaatatttca gcttctggtg gagtcaacgg tacagttaga ggcgaattga agattttcaa
     1081 atatatcaat gacacagaga ttggtatccc aaatgtgact ttcgaattaa gacgagcaga
     1141 tgaacagcct attcaaggac agtctagtat cctgttgact tcgaatgaac agggagaagc
     1201 tagtatcaaa ggcctgcaag taggagacta tgttgtaaaa gaaaaagaag cacccaattg
     1261 gattgatttt gatccactaa gttcaaatga actcaaattc tccataaacg aaaatgatac
     1321 agagggagtc agtttaccta tttataacaa gaaaaaggtt acgaacatca cagcaactaa
     1381 aatttggaac ggtggaacca ctccaagacc gagtatttat tttaaattat tcagagcaag
     1441 tacaaacaat tgggaaccag ttcctgatgc agaaacaaaa cgattagaca atggaataac
     1501 ttcagtgact tgggaagata tccaacagta tgatgatagt ggaaacgaat atacgtttaa
     1561 agtgcaagaa gtagatcaaa acggaaatga ttatgtccct tcaggttatc aaaaaattga
     1621 aaacgggcta gtcgttacaa atgagaataa agaagtcatt tcagtctcag gacaaaaaac
     1681 atgggaagac aatgagaacc aagacggcaa acgaccgacg acgatcacag taaatctatt
     1741 agccgacggt caaccgatcc aacacaaaga agtaagtgaa aaagatgatt ggcgctatcg
     1801 tttcacaaat ctgccaaaat acagagacgg gcaagaaatc atctatactg taacggaaga
     1861 caacgtgccc gaatacagta cgacgattga cgggtataac atcaaaaaca gttatacacc
     1921 ggaaaaaaca aatatatcta taccaggtag ccatataaca ccgtggaaaa attttccaga
     1981 gaagacagag agagagaaaa ttagaaatct attctctcaa aaattgcaaa tatttgctca
     2041 tacaggagaa tccagcgaac aaagaagcaa ttatattagt aagagagctg tacctaaaca
     2101 gataacaaat aaatcaaaaa gcattcttcc taaaacaagt agtaaaaaat ctagttttgc
     2161 tgtaatcatt ggtttattga tagtaact
//
LOCUS       DADVXM010000148         2056 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.158, whole genome shotgun sequence.
ACCESSION   DADVXM010000148 DADVXM010000000
VERSION     DADVXM010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.158"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(48..1868)
                     /locus_tag="KB927_002611"
                     /pseudo
     CDS             complement(48..1868)
                     /locus_tag="KB927_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
     gene            1942..>2056
                     /locus_tag="KB927_002612"
     CDS             1942..>2056
                     /locus_tag="KB927_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBB6841485.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
BASE COUNT          701 a          399 c          278 g          678 t
ORIGIN      
        1 tatatattta aaaaggaaaa ggacactgtt taaatagtaa acgattctta attaagttta
       61 cttctatttt cttgaaattg aataattttt tcagaaaatc catttgcaac tttcccctca
      121 tctccaataa aatcaagata agtaaaatct gtcccaagtg aattattaac tattttatca
      181 atgaaaaatg aaattatccc tacacctaag atatcaactg tttcgtcatt ttctaataaa
      241 ctatttgtta ctgaagcgat tttatctgaa gaaccaaatc tgttcttaac aaattgatta
      301 aatctatcaa tagcaccctt atcacaatag tacgttttta aagccgataa agctgttgaa
      361 tcagaatttc tttttgctaa ggtataaaca tttaccgcgt caacatcttg gtataaatct
      421 tctagactaa atgttccacc tgcagccgta cctactaatg caaatacacc ttgctccatt
      481 tgtattccta atttcttaac ttcaccccag caagtcatta aatctcctaa ccaacctgca
      541 aagtcagaaa cactatcatt gattgtgtcg gctagaaaca tctgtgattg taacgtcaca
      601 attaagtgag gcaaacctat tattgaacca gtattaggat ctataaaata attatacagg
      661 ccctcgctat tagttaattt attcctatat tcatcataaa tttttctatc atgctctgtt
      721 acaggagaag aaatgatgtc ccatgacaaa ccagaataat ttacatatct ataaaatgtc
      781 aaatgagggt tccaaggatt atcaagacca gcttgtgata gatattgata cgcacgtacc
      841 atctgattta taaccttctg attgtatttg gcaatgtaat tatcattatt agtatcattt
      901 gataactcat taaatccgct atctctaccc gatgtagcga ttaaatcgat accaacagct
      961 ccgttgccac ttcctatggt aaattcaaca aattgatcaa aagaccattg tctaggcata
     1021 ggaaaaccta aattcccact ataaccagtc gacatatctg aaacaaatgc aaacgaagca
     1081 tacccgttat tgattatttg agaacaaaca tttcttgttc cgtaaacacc cgtttgatac
     1141 ccgctatatg acattacagc agataccccc ttaaaatatt ctccagcata tgcaagaatt
     1201 tcttccccta acatgtctag atcaacagca aaataaataa ctgttgttaa tggtatattt
     1261 agattttttg ctgcatctat agccttctta ccatctgata agccacgatc ataagtaaaa
     1321 taagctaatg ctgcacctcc atcttgatag ataggaaaca cagataaatt tttagaaaaa
     1381 atattattca attcctctgt agttagatac ttatttcgtt catcttttcc aattccaaca
     1441 gtaccagtaa gatatctacc aactattttt atatcattat caaccaatgt ttggatttga
     1501 gatctagtta attgcgtaga agtatctgcg ccatctgcag atcttctaat atctccagcg
     1561 ctagacaata gtccttttat tacaacaaca tctgctattt cagtatattc aggcaatacc
     1621 ataaattttc ggaatgccag tacttctaaa cccatatatt tagtgaaaat accatcgaat
     1681 gtaccgtctt caaaataacc attaacatat aatccatatt gaattattct tacatagttt
     1741 cccgagttac cttcagacac aggataagtt ttactagttg tcccattacc ataagaccct
     1801 gttgcttcac tgggagaata tcctagttca gcttgtaatg caaaaattaa tgcttgattt
     1861 gaatttcggt tctgttgcaa agttttaaat ctactatcaa ataagataga ataatagaaa
     1921 aagatagcag gaggaataac gatgaatcat tttaaaggaa agcaatttca gcaggatgtg
     1981 attattgtag ccgtgggcta ctatcttcgt tataacctta gctatcgtga agttcaagaa
     2041 atcttatatg atcgtg
//
LOCUS       DADVXM010000149         2051 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.159, whole genome shotgun sequence.
ACCESSION   DADVXM010000149 DADVXM010000000
VERSION     DADVXM010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2051
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.159"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            70..2016
                     /locus_tag="KB927_002613"
     CDS             70..2016
                     /locus_tag="KB927_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBB6841486.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFVFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVYSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT          658 a          341 c          369 g          683 t
ORIGIN      
        1 agatatgcta aaataaattt gcatttcagt gaaccgtttt cacgtaaaaa taaaaaagga
       61 gtgattcgaa tgaattacag taaagtagct tccgacgtaa tacaagcggt cggaaaagat
      121 aaccttattg cagctgcaca ctgcgctaca cgtcttcgtc tcgtactaaa agatgacacg
      181 aaagtgaatc aaaaagcttt agacgaaaat ccagatgtga aaggcacatt taaaattgat
      241 ggacaatatc aagtgattat cggtgcaggt gatgttaatt tcgtttatga cgaacttatc
      301 aaaaaaactg gactttcgga aatttcaaca gatgatttaa aacaaattgc tagtaaagat
      361 aaaaaattca accccattat ggcattaatt aaattattat cagatatttt tgttccaatt
      421 atacctgccc ttgttgcagg tggtttatta atggcattac aaaacttttt aacagctgct
      481 ggactttttg gaccaaaatc aattgaagaa atgtatcctg cgattgaagg tatttcctca
      541 atgatccaac tgatgtccgc tgcaccattc atgttcttac caattttagt aggtatttca
      601 gctgctaaac gttttggagc aaaccaattt cttggtgctg caattggtat gatcatgaca
      661 acaccagatc ttggtggctc aactgaatat tggaatattt ttggttatca tgtttcacaa
      721 acaaactatg cttatcaagt tattccagtt ttagcagctg tttggatatt atctatatta
      781 gaaaaattct ttcataaaaa attgccatca tctattgact ttacattcac gccattatta
      841 tcagtaatga ttactggatt tttgactttc acagttattg gccctgtaat gttattgttg
      901 tctaatggaa ttacagacat tattgtttgg ctatataaca ctactggatt tattggaatg
      961 ggtatttttg gaggaacata ttcacttata gtcatgactg gtttacatca atcatttcca
     1021 gctattgaaa ctcaattact ttcagcgtgg acaaatggta tcggacatgg agactttgtc
     1081 tttgtagttg catctatggc aaacgttgct caaggtgctg caacatttgc catttggttc
     1141 ttaactaaaa attctaagac aaaaagtctt gcttcctctg cgggtgtctc agcacttctt
     1201 ggaattacag agcctgcctt gttcggagtt aacttaaaat accgctttcc attcttttgt
     1261 gctttaattg gttcaggaat tgctacagca gtagcaggat tacttaaagt agttgctgtt
     1321 tcacttggtt cagcaggttt cttgggattt ctttcaatta atgcaacatc tatcccattt
     1381 tacgtattgt gtgaattgat tagctttgta gttgcttttg caattactta cttctacggt
     1441 aaaacaaaag ctgctggtat ctttaaagca gaagaaattg ctgaacaaac accagttaat
     1501 tcttcaaaag tagcaacaac agatccaata tctactgatg ttgaatcaac acaaacaaaa
     1561 gtttcatcag aaacaattgt tagtcccatt tctggtaaag tgattagtct ttcttcagta
     1621 aatgatccag tcttttcatc agaagctatg ggaaaaggga ttgccattaa accaaatgga
     1681 aacacggtct attctccagt agatggtact attcaactca cgtttgaaac tggacatgct
     1741 tatggtatta aatcaaataa tggtgctgaa gttctaattc atattggtat tgatactgta
     1801 tcaatgggag gaaaaggatt tacacaaaaa gttactacta atcaaaaagt tagaaaaggc
     1861 gatattcttg gagcatttga ccgttcaatg attgagaaag aaggtcttga tgatacaaca
     1921 atgattattg tgaccaatac ttcggattat tcagaagtaa atatagtagc tgaaaataca
     1981 gtcactgagg gtactgattt acttgaaatc aaataaatgt atttccctga gtaaagatgg
     2041 aattttcttt c
//
LOCUS       DADVXM010000150         2047 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.160, whole genome shotgun sequence.
ACCESSION   DADVXM010000150 DADVXM010000000
VERSION     DADVXM010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2047
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.160"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(555..920)
                     /locus_tag="KB927_002614"
     CDS             complement(555..920)
                     /locus_tag="KB927_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841487.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(996..1241)
                     /locus_tag="KB927_002615"
     CDS             complement(996..1241)
                     /locus_tag="KB927_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6841488.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1311..1565)
                     /locus_tag="KB927_002616"
     CDS             complement(1311..1565)
                     /locus_tag="KB927_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841489.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1729..2034)
                     /locus_tag="KB927_002617"
     CDS             complement(1729..2034)
                     /locus_tag="KB927_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841490.1"
                     /translation="MPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVITLLLLV
                     MMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINPLIFSR"
BASE COUNT          755 a          356 c          366 g          570 t
ORIGIN      
        1 gtctgaaaac aaaaaaagaa agcgttatta ttttagtcta ttttcagggg gggaacctta
       61 tgataaaaaa actattttta ctatcaatat taacgctagc aatggcaggt tgttctgact
      121 ctggcttagc aactgaactg atcacaaaat caactgaagc cacgacagag gagttaaaat
      181 gtggaaacga tcacagtgac tacagaggct taaatcgacg atgcatggga atattaggca
      241 gaagcaattg taagcatcga tgtagtaatc gaagaaggtg tagaagaagc aacagaaaaa
      301 tcaaaagaaa gatcaaaaga agcaatctgt gctgtgcatc gtatacagac gtcgaagatg
      361 cggtactttt aaaccacgtc aggagatgtt catttatgtc tagggaagtt ggcgatgaac
      421 caaaactaga gtacgctttt agttttgcac gtgaggatga agataaccct aaaacttacg
      481 acattttagc ttgatctaag atggttaaag ctttttaatg aagtaagagg agatagaagg
      541 cttttctagt tatattaggt aagataaatt cctttttgct ccaaatttgc taaacattct
      601 gctagataaa cttcatcgtg ttccggataa atcggcacgt tgcgctctac agtaggtaaa
      661 tcaaaaaatg cttcgcatga tttgccacga tacataggat ttttccactc tggtgctggg
      721 ctgtaaccac gtttttccat ttcatccatg acaagctgat gatattggaa taatctataa
      781 ggagaatagt gaaaaacata atccacagta gcatgtttct ttccccagcc atttcctctt
      841 aatgcacagc attcccgatg ttgtcctaaa agctgttgac gaggaagctt tgaaatcaat
      901 ttttcatgcc ataatcgcat agaaatgtct cctttatata tagattgtta accttagacg
      961 ttaaatgaaa aaaccagcac caaggctgga aaaaatcact tcagtttgct tgctgtttct
     1021 gagcgaccaa ttaggtaatc aacggaaata tcgtaaaagt cagcgatata gattaattca
     1081 atgatgcttg gaatttcttc tccttcttcg tacttacgat atttgaataa aggaatactt
     1141 aacgcgctag aaacagctac ttgagataaa gatcggccag ttcttaagaa attcagacga
     1201 caacgtaaag tatccagtaa aatagcttct tcgatactca tttaatcacc tttcattata
     1261 gtagaatagt tataatgact atagaaagct acacatgcaa tcaatagtac tcaatgtttt
     1321 ttatttaaac gtatcaaata aagaatgacg atcaataaag acaaaaccag tcctgataat
     1381 tcttctataa aaacactatc gggttcaaag tagttgtaat taaaaacttt ccacataaag
     1441 tagatagccg gaagagtcaa aatagctaaa taaaaccgtt ctttgttcca attcataaga
     1501 taaacaatac ttgcgaccag tgcgaccgca ggcacccaaa acaaaactct caccaacgta
     1561 atcatgtaac ggactcctca acgattcata taataaaaga taacatgtta ttgcatacat
     1621 cacaaatgaa atgctaggaa aataaaagaa gaatagatca atgaaaaatg aaaaagcaga
     1681 acagttttct gctgataagc aggaactgtt ccgctgaatg tgtcttatct atcgagaaaa
     1741 aatcaatgga ttgatatcta agtaattcaa tacatataaa aagaggacga tcgcattcac
     1801 taaaaaggaa agaatgatga tcccatagcg aatggaaaca tatttaacaa atacttttgt
     1861 ttgaatacgg gcatatcttt ttcctttata gctgagcatc atgacaagaa gcaaaagggt
     1921 aatcacacct tgaaaaatca ttccaataaa cagaattcct gaggtttgat aatttaattg
     1981 gagaaaataa gctgctgccg caactaaatc gaataaaatc gcaataaatg gcaaaataat
     2041 cactcct
//
LOCUS       DADVXM010000151         1967 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.162, whole genome shotgun sequence.
ACCESSION   DADVXM010000151 DADVXM010000000
VERSION     DADVXM010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.162"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            271..837
                     /gene="amaP"
                     /locus_tag="KB927_002618"
     CDS             271..837
                     /gene="amaP"
                     /locus_tag="KB927_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBB6841491.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            850..1038
                     /locus_tag="KB927_002619"
     CDS             850..1038
                     /locus_tag="KB927_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBB6841492.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1051..1608
                     /locus_tag="KB927_002620"
     CDS             1051..1608
                     /locus_tag="KB927_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6841493.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1640..1882
                     /locus_tag="KB927_002621"
     CDS             1640..1882
                     /locus_tag="KB927_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6841494.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          716 a          305 c          404 g          542 t
ORIGIN      
        1 taaatagaat cttgtaataa taactgagca taatctttgc aatttttaat cttgaataat
       61 atcctttaag tatagccagc aatcaaaagt aaatagagaa taagtaagca attgttattt
      121 cagtatcaga ctggcaataa aacgccgtta tgatccagca atgtttggta gcgctttatt
      181 tactgatgct atgctaactg ttcgctatct atactgtgat tgtcggtaga gttatttaca
      241 gggtaaaaat aagtttatag gaggtggaaa atgaataagg ggttaaaaat aatcggtgtt
      301 atcatgagtt tactgctact ttcagtattt ctagcgattg cgttgatcaa tgcgccgtat
      361 attatgcctg aacaattgga acgatttcgc ttctttactt taacgaatta ctacatgcaa
      421 caatatattt tctgggcagc tgtagtattt gccgttcttg ctattatcat cttgctagtc
      481 gttcttttct atccaaagtc aagaggaact ttcgttatga aacgggaaga tggcaaacta
      541 acaatcgaca aaaaagcgat cgaagggttg gtacgttccc atttacacga agaagagttc
      601 attcattcac ctaaagtacg gatacgttca acgaaaaatc gaatccatat ccatgtcaac
      661 ggagacttga aacgaacttc ttcattagta gggaaaacag gtgtattgat gcaagatatc
      721 gaagaagaag taactaaagt actcggaaca aaagaaacgg tcaaagtggc agtcacatac
      781 agcggttatg aagaacaaga agatacaaga gactacaagc actctcgagt ggaataggag
      841 ggccaaataa tgaaagaact attttcagca tacaagctcc ctattatctt tgggggtctt
      901 ggactactgc tagctgtttt atggttaacg attggatttt tcaagacatt gttgatcata
      961 atcatgacag caattggcgc aggaatcggt ttttatttga aacagtcagg aatagttgat
     1021 caatttttta aatcatagga ggaaacaaag atggaaaaca aaaacatgaa tacaacaaat
     1081 ggatcagttt tggcaaatga aaaaggagaa aaccgcatga tgaatggtga attgacttat
     1141 gaagacaaag tcatccaaaa aatcatcggt tatgcattga aagatgtaga tggtctattg
     1201 acattagatg gcggattttt ctcaaatatg gctgaaaaat tagtcaacac agataacgta
     1261 acagcaggta tcaatacaga agtaggtaag aaacaagtag ctgtggatct agatgtgatc
     1321 gtagaatacg gtaaagacat cgaagatatt tacaaccaaa tcaaagaatt gatcagtact
     1381 gaagtaaaca atatgacaca tttagatgtt atcgaagtga atgtgaatgt tgcagacatc
     1441 aaaacacaag aagaatacca aaaagatcaa gaaacagtac aagacaaagt aacagaagca
     1501 gcaaaatcca caggacaatt tgcttcacgc caaacagata aagcaaaatc tgctgtaggc
     1561 aaaggtgcac aaaaagtcaa agaaaataac gaaccacgtg tacaataaga agtaagaagt
     1621 cagttaggag gaatttaaaa tgggatttat ttgggcatta atcgtcggcg gtatcattgg
     1681 agcaattgca ggagcaatca cgaataaagg atcatcaatg gggatcatcg caaacatcat
     1741 tgctggttta gtaggttcag caattggaca agctttacta ggaacttggg gaccaacaat
     1801 tgcaggaatg gctatcattc catcattgat cggtgcaatc attttagtat tagtcgtttc
     1861 attctttgca cgtaaattat aagcaaattg aagaaaaact tatgttgaaa tgaagaacaa
     1921 atttgagaac cgtagcgaca ctcgctgcgg ttctttttta tatattt
//
LOCUS       DADVXM010000152         1952 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.163, whole genome shotgun sequence.
ACCESSION   DADVXM010000152 DADVXM010000000
VERSION     DADVXM010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.163"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..350
                     /locus_tag="KB927_002622"
     CDS             <1..350
                     /locus_tag="KB927_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6841495.1"
                     /translation="VNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSD
                     APIILADEPTGNLDSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGK
                     KLKKVNKMNLEVE"
     gene            350..1726
                     /locus_tag="KB927_002623"
     CDS             350..1726
                     /locus_tag="KB927_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6841496.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
BASE COUNT          770 a          228 c          351 g          603 t
ORIGIN      
        1 tagtaaataa atcagcagat gaaagtatct tgtttgaact aggtttagat aaaaaacaaa
       61 taaaaagaaa tgttatgaaa ttatctggtg gacagcaaca aagagtagct attgctagag
      121 cattggtatc agatgctcca ataatactag ctgatgagcc tactggtaat ctagacagtg
      181 ttactgctgg agaaataatt aatatattaa agacattagc taaagataga aataaatgtg
      241 taatagttgt aacacatagt aaggaagtag cagattctgc ggatatcatt ttagaactaa
      301 gtggtaaaaa gttgaaaaaa gtaaataaaa tgaatttgga ggttgaataa tgataaaaaa
      361 tgcatttgct tatgtaacta gaaaaagttt aaaatcatta attatcatat tagttatttt
      421 atctatgtca actttaagtc tcattagttt atctattaaa gatgctacgg acagagcttc
      481 aaaagaaaca tttgctaata taacaaatag tttttctatg gagataaata gacaagtaaa
      541 tccaggaaca cctagaggtg ggggaaatgt aaaaggtgaa gatattaaaa agatatctca
      601 aacagatagt atagactcct atgtaaaaag aataaacagt gttgcagatt tagttgatta
      661 tgatattatt gaaactcaag agactcttgc gaatcaatca cctgaaagag caaagaattt
      721 taaaagaaca gttatgttaa ctggggttaa cgactcaaca aaagaaacaa aatttgtatc
      781 agaagcatat aaattagtag aaggaaagca tttagaaaat gaagataaaa ataaaatctt
      841 aatgcataaa gatttagctg aaaaaaataa ccttaaagtt ggagataaga taaaaataaa
      901 atctaattta tttgatgctg ataatgagaa aggtgcagat gaaacagtag aagtagaaat
      961 taaaggtcta ttcgatgggc ataatagcgg tggagtaagt gcagcacaag aactatacga
     1021 aaatacatta atcactgata ttcatacagc tgctaaagtt tatggtaata ccgaagatac
     1081 agctgtatac caagatgcaa cattctttgt aaaaggtgat aagaatcttg atagtgtaat
     1141 aaaagatctt gggaaattag atataaattg gagagaatat aatttgatta aaagttcatc
     1201 aaattaccct gcattacaac aatctatatc aggtatttac tcaatttcaa ataaattatt
     1261 ttttggctca ttaatatttg caggagttgt agtttcatta ttattattct tatggatgaa
     1321 tgctagaaag aaagaaatag cagtattact atcattaggt atatcaaaat tagaaatttt
     1381 tggtcaattc ctaattgaga tggtatttat atcaatcccc gcattcgttg gttcctattt
     1441 cttagctcaa tatacagctg acaagcttgg gaataatata ttgaataagg ttactggtga
     1501 tatagctaaa caaatagcta aacaatctgc atctagccaa ttaggtggtg gggcagaagc
     1561 tgaaggattt aacaagacat tatcaagttt agatatcaat gtattaccta aattcatgat
     1621 ttatgtagtt atatttatga gtttagtact tcttgtatca ttgattattt cttcattcaa
     1681 tatattaaga aggaatccaa aagaattatt aattgacaat aattaaaatt ttcggtgctt
     1741 tttagcacca aaaatgagag tgtaatataa accgtgtaag taaccatcaa tcctaggcgg
     1801 gtggttgctt cacggttttt atttttctaa aataagatca agaggtgatt acacgatggc
     1861 tagaaagaaa agaaatcctg atgctgagaa gttagctgaa tccattttga atacttatca
     1921 acccgaatct gtagaggata tgcaagatgt tt
//
LOCUS       DADVXM010000153         1910 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.164, whole genome shotgun sequence.
ACCESSION   DADVXM010000153 DADVXM010000000
VERSION     DADVXM010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.164"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            492..710
                     /locus_tag="KB927_002624"
                     /pseudo
     CDS             492..710
                     /locus_tag="KB927_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            970..1224
                     /locus_tag="KB927_002625"
     CDS             970..1224
                     /locus_tag="KB927_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6841497.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            1225..1542
                     /locus_tag="KB927_002626"
     CDS             1225..1542
                     /locus_tag="KB927_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBB6841498.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT          661 a          300 c          355 g          594 t
ORIGIN      
        1 cattatatca ccaaacccca tcagcgtgca ggctgatggg gtttttttac gtttctatat
       61 tatagaatta acgggtaggc ttactgtctt ttttggcaat tttgcaatca agccatttgc
      121 agaggtaact gcacactaca tctgcaaatg gcttgattgc aaaaacaaaa tcaaaaaggt
      181 atttcattat atctcctcct ccccttgaca gattaggccg gggtagcaga cagcaaaact
      241 attataacat aactgaaata cctaaatgac atatacagat atgataattt atgtattgat
      301 ttttctaaca aaagcacata ttttaatata tactacctat tttaggtagt atatattttt
      361 agatacaata tcgatcagtt ttgaggaaat gaaattctag atattttttg ctaaatagag
      421 ttactttcaa tattttttaa cgtaattagg cagaagtcac tcatcctcta taggtttgtg
      481 atgaaattgc cattgatcca tttaagtaag agcaaaaaac tggaggttta tcaggtaatt
      541 ggtctaatgg atttaagtat gcggtcaccg tgtatagagt tgcttatgag attcaagaaa
      601 ataaagttat tccagtattg ctatatggaa cacataacaa tttttatgaa ttagccgaga
      661 acactcgcaa ctttattcgt gtagatgaat cggcttcggt tgagttataa ctttagctat
      721 atcaatcaac cgaccgacat atgttaaatc tatatataat aaaaatacct acttaaatgg
      781 atgttaacgg aagtgtatgg tgagtagttc actcgtattt tgatatcgtt tgtatatgtt
      841 ttcagcgttc taagtggctt attttgtcca ataataatat ggagtggaat cccttaagaa
      901 acaccgttgg caattgttgt tataacatgt tataatttat tcatcaaaaa ctaaaaggag
      961 tgtgataaca tgggaaaaga actaaaggtt agaaagatcg gcaatagcgt gggagtgatc
     1021 cttccaagct ctcttggatt aaaaagcgga gacactatcc aagccaaaca agaaggcaac
     1081 ttattcatat tagatactac tcaaatagca aaagaacacg atcgcaaatt gattgaagaa
     1141 agtttccaag actttgagaa aggtttaaca gtttcagaaa ttgaaatggt aaaagctttc
     1201 ggaaaatacg gctggagtga atagatgaaa gagtacacgc tagtttattc taaaagtttc
     1261 cagaccagcc ttgaaacgat aatagaagaa tgggaaaatg agcttgctct gtctccagcc
     1321 agcataaaaa gatttgtagg tgcgatccag aaggctttag aactaaccaa aaattttcca
     1381 actatgcatg aggaagtttc cgaaatctat ggaatggata tcccaacata tcggatcgtg
     1441 atcggcaaaa gctatgcctt attttatcgg atcgaccatg aaaaaaaaga gatacttgta
     1501 ggacgtattt tccaatctaa acaaatgaaa ctaggctttt aacaataatt aggcaaaagt
     1561 cgctcatcct ctacaggtgg gtgattaatg ccgctcgata tggttgttaa ccgtcggtta
     1621 ctcgaagatt gatatataag acttagtacc tttttatttt gctccatgtt atggccgaag
     1681 gtctaaagat acaatcatta gtctagagaa aaattaagaa ccgtaggaac tacggggatc
     1741 gcttggtgaa taagagacac tgctattagt gaaaaaataa gatatcaagt acgctctatt
     1801 cccaaaaatt tcgtgacttt actcatgaga ggttcaagta gtatattttt aatcaaaatt
     1861 gacgtaactt ttaataaata ctacctaaat aaggtagtat ttatttttgt
//
LOCUS       DADVXM010000154         1901 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.165, whole genome shotgun sequence.
ACCESSION   DADVXM010000154 DADVXM010000000
VERSION     DADVXM010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.165"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..202
                     /gene="tnpB"
                     /locus_tag="KB927_002627"
     CDS             <1..202
                     /gene="tnpB"
                     /locus_tag="KB927_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBB6841499.1"
                     /translation="QDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVR
                     WLLEGLSIDQPRAILPGKKGVF"
     gene            304..1851
                     /locus_tag="KB927_002628"
     CDS             304..1851
                     /locus_tag="KB927_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBB6841500.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
BASE COUNT          633 a          343 c          399 g          526 t
ORIGIN      
        1 tcaagaccgt ttcaaacttc tctattggga cggtgatggt tttcttctct gttataagcg
       61 gatagaaaac ggcaagttaa aatggcctcg gacgaaagac gaagttcgaa ccttaacgaa
      121 ccaacaggtt cgatggttgt tagaaggatt aagtatcgat caacctcgag ctattttgcc
      181 aggaaaaaaa ggagtttttt aagctggggg gttaacacaa aaaatgtgtt gaacccctat
      241 ttcttgtgcg tttcttgtgg tattctgtaa caaaatcagt tcgattcaag gtggtgaaaa
      301 attttggaaa ctacagatac gttgcttcag ttgcttcaag aagcccataa aaccaatcaa
      361 gcacaacaac aaaccattca gaatcttaca actgaaatcc aactattgaa tgaaaaggtc
      421 aattatttaa ccaacaaatt atttggacgc tctaaagaga ctctctttga ggaaacgaat
      481 gggcaattga atctttttag tgatgaagaa atttctgtaa gtgttccaga agcagctgcc
      541 accattattc cagtaaaagg acatcaacga gttgtaggaa cgaaagcaga caaaatcaaa
      601 cacttaccta taacagagaa agaacatctc cttcctttgg aagaacaatt ttgtgaacat
      661 tgcggttcac agatgaaaga tatcggacgg acaaaagtac gagaagaaat tcgtttccat
      721 caggctatgt tggattgtct cacccattat caacatacct attgttgtaa aagctgcgaa
      781 aaagaaggac tttcttcttt taaaaaagcg atcgttccta aacctttgat ttctaatagc
      841 ttaggttcca atagtttagt ggcggaaacg atccggatga aatttggtca gaaagttcct
      901 gcctatcggc aagagaacta ttggaaacaa acacatgggt tggatatttc gagagataat
      961 atcaccaatt ggcatattaa agcagtgcaa aacgcgttag accctttagg agaacgatta
     1021 agagtctatc ttaatcaaga agagattcta cacggggatg aaacaagtta tcgtgtgatt
     1081 gaaagtgcca aaacagatac ctattactgg cagttttgta caggaaaaga cagtcagcat
     1141 cccatcgttt attatcacca cgacgaaagt cgtgctggag atgttccgaa aacttttctc
     1201 aaggagttta cagggtattt acactgtgac ggctatagcg ggtataatgc cgtggaaagt
     1261 gtacgacttg tctattgttt cgcgcatgtt cggcggaaat ttttcgaagc aattccaaaa
     1321 ggaaagaaaa acacggatat tcccgcagct caagcagtca aacaattgga taaatggttt
     1381 gtcctagaaa agaaatggaa agacttttct cctgagaagc gattaagctg tcggcaacaa
     1441 gaactgcgtc cattatttat tgctttttat gagtggatgg caacgataga tcctgttgca
     1501 aaatccaagt tggatgcagc cgttcaatat gcgtgtaaac tacgaagtgg ttttgaacct
     1561 atttttgaag atggtcgttt agaactcaca aataatcgtg cggagcgaaa tatcaaagag
     1621 ctggtgatag gacggaaaaa ttggttgcat tccacaagtc ttgaaggagc acgaacttca
     1681 ggaatcattc tgagtgtata taaaacagca gaacttaacg gattgaatcc tgtaaagtat
     1741 ctagagtttc tatttgataa gataccaaat cttcccgtac tttcagcaga aactttagat
     1801 caactgttgc cttggaacaa ggatgtacaa caacattttt ctcgtaacta aaaacgccaa
     1861 acattcccga ttctattcta taggtcgggt tatttgacgt a
//
LOCUS       DADVXM010000155         1886 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.166, whole genome shotgun sequence.
ACCESSION   DADVXM010000155 DADVXM010000000
VERSION     DADVXM010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.166"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(67..1098)
                     /gene="queA"
                     /locus_tag="KB927_002629"
     CDS             complement(67..1098)
                     /gene="queA"
                     /locus_tag="KB927_002629"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBB6841501.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1291..>1886
                     /locus_tag="KB927_002630"
     CDS             1291..>1886
                     /locus_tag="KB927_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6841502.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT          541 a          394 c          350 g          601 t
ORIGIN      
        1 tttttctttg tcataaaatc tttgtaaagc ttttttgtta ttcaaaacta gcggcttttc
       61 ataaccttat ttcacgaaca tcgcatctcc aaaactaaag aaacgatagc gctcttcaat
      121 cgcatgctgg taagcagata aagtcaattc tcttcctgca aaggcactaa ctaacatgac
      181 taaagtcgat tttggcaaat ggaaattagt tgagaaagct tctaccactt tgaattcata
      241 gccaggcgta atgaaaatat cagtccatcc gctgtctgct ttgatttctc cattaaattt
      301 cgttccaatc gtttctaatg ttcgaattga agttgttccg acagccacga ttttcccgcc
      361 atttttacgt acttggttca atcgctcagc cgcttcttcc gtcaaacggt agaattcact
      421 atgcatatgg tgttcttcaa ttttatctac gctgacaggt cggaatgtac ctaaccctac
      481 atgtagtgtc agatagacta attcaacacc ctttgcttcg atctcatcaa gtaattcttt
      541 cgtaaaatgc aatccagctg ttggcgctgc agcagaacca ttttctttcg catagacagt
      601 ttgatagcga tctgggtctt ccagacgttc tttgatatat ggaggcaatg gcatttctcc
      661 caatgattca agaatctcta gaaaaattcc ttcatactca aagtcaatga tccgtccgcc
      721 gtgttccaat tcttctttca ctactgcttg caatctgcca tcaccaaaag agattcttgt
      781 cccaactttg gcacgtttcg caggtttgat caatgtctcc cacgtatctc cttgtgtatt
      841 cgttagaaga aggacttcta aatgcgcacc agtatctggt ttttctccat ataaacgagc
      901 aggcagaact cgtgtattat tcataactag cgcatcacca ggctgtaact cttcaatgat
      961 ttcatggaaa tgtttatctt ccatctctcc agttttccga tccaaaacaa gtaaacgaga
     1021 atgatcgcgg tcttttaatg gtgtttgtgc gattaattct tccggcaagt caaaatcaaa
     1081 atcttctgtt gttaacatat cgtcactcac tttctatcat gtgcttcatc attctatcat
     1141 gtttttcgtt ctgttggcaa aatcagcact ttttcacttc tattttttgt tttcctaaat
     1201 aaaaaaacta ccctatttgt attttttcat tgttttaggc atactagtaa tagatagttc
     1261 ttcattgaaa atagaaaaag aggtggcacc atgattgaat ttcaaaatgt gtcaaaaatt
     1321 tataaaggtg gaaaagtcgc tgtagaggac gtcaatcttt catttgaaaa gggtgagttc
     1381 atttgtttta tcggtacgag cggaagcgga aaaacgacga cgatgcggat gatcaaccga
     1441 atgactgatc caacacaagg gaaaattttg attgatggaa aatccatcca agaaattgat
     1501 ccagtggaat tgcgacgtca gatcggctat gttatccaaa gtattggatt gatgcctcac
     1561 atgacgatcc gtgaaaatat cactcttgtc caaaaattgt tgaaagtcag tcaagaagaa
     1621 cggaataaaa cagctgaaaa aatgattgat cttgtggaat tgccccgtga gatgttagat
     1681 cgctacccac atgaattatc tggtggtcag cagcagcgta ttggagtcgt tcgtgccctt
     1741 gcagcgaatc aagatatcat cttgatggac gagccattcg gtgcgcttga tccaatcact
     1801 cgtgattcct tgcaagacct tgtcaaagat ttacaagagc gtttgggaaa aacgatcgta
     1861 tttgtaaccc atgacatgga tgaagc
//
LOCUS       DADVXM010000156         1787 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.167, whole genome shotgun sequence.
ACCESSION   DADVXM010000156 DADVXM010000000
VERSION     DADVXM010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.167"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            19..828
                     /locus_tag="KB927_002631"
     CDS             19..828
                     /locus_tag="KB927_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6841503.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            868..1365
                     /locus_tag="KB927_002632"
     CDS             868..1365
                     /locus_tag="KB927_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6841504.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
BASE COUNT          619 a          322 c          341 g          505 t
ORIGIN      
        1 agaaagtagg aagataaaat gaaactagca gcgattgatt tagacggtac cttgcttgat
       61 cgaaatggaa agataccaga agaaaatatc caagcacttc ggaaatttga tgaaaatggc
      121 ggaatcgtaa ccgtcgctac cggaaggaac agcatttctg ctaaagatat tttttccgaa
      181 ttaggaatcg gtggctattt gatttcttcc aatggttcac tgattgctga aatgaaggat
      241 ggaaaaatgg cgaaagttct cagacgttca aaaatagata gcgatacact gagaaaagcc
      301 ttcttctatg ctcaagaagc gaaaatatcc atcattgcta gccgagaaac ccaagatgat
      361 cagctgacat tcgatgaatc aaatctagtc aaagatgacc cttattatga acatttcaat
      421 ttacagaacc attcttttga tcaaatttta aatatgttgg aagatccttc tcttagctat
      481 cttaaattag cattaacaga taagagtgaa gaaaaactac agaagctaca aagagatctg
      541 caagcagatg gtatccaatc agtattctct gatccgcatt tcttagaaat cacgcctaca
      601 ggtatcacta aagctcattc acttgttttt ctggcggatt accttggaat cgaatcgagt
      661 gacatcatgg cttttggcga tcaagaaaac gacattgcta tgttgaatta cagcgggttg
      721 agtattgcga tggggaatgc acagcgacaa gtaaaagaaa ttgcaaacca agtaacactg
      781 acgaatgaag aagctggtgt tgcttatatt ttaaaaaact tctattaaaa agaataaaat
      841 gacgatatga atgtaggagg aaagaaaatg ttagttatta ttgatatgca aaatcatatt
      901 cttgatccaa acagcgaatt ttatattcca gagtcagatc aattggcaga acgtattgct
      961 caaagattag ctaaagcacg ccaaaataat gaatatattc tcttcacacg ggatatacca
     1021 gttgaactga aggacaaaga agaagaacga gaagatttgc aattgatccc tcttctttct
     1081 ccacaagaaa atgaacgagt gattaaaaag tattacttta cgattccacc tgaaacttta
     1141 gctgaaatcc aggaaacttt atttgaaagc aaagaagaac aaaaagagat cgaagtagtc
     1201 gggattgaaa caaacttgtg tgtactctct aatctgatag gcctgcagag tgcttttcct
     1261 gaagcagact tttttgttga tccaatgtta gtctccagta gaaaacacgg agaatccgct
     1321 ttagagctgt tgaaagattt caacgtctct atcgtcgaat cataaaaata tctatcttca
     1381 tttacgatat ttaacacaca ataaaaaaag cacgcagaac tgttttagtc ctacgtgctt
     1441 tttctatcaa agtagattgg cttttttatg acacagagtg aaacggcagg ctcacgacct
     1501 ctttcttaaa tggtgttcaa tcagctgacc ctcggtatta gcttaacaaa cggcaaaata
     1561 tgaggaacta tttttccgtt tgttaagcta atactcaggt caaaacgctg atttcacaac
     1621 ctcttcctta aacggtattc aaaagcttgc atctgcagta ataagaacag ccaagtaaaa
     1681 acataagaag ctgtttttac ttggctgttc ttattacttg atgcagggca gctttttcac
     1741 aacctcttat gtaccttgta ggactcgaac ctacgaccgg acggtta
//
LOCUS       DADVXM010000157         1776 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.168, whole genome shotgun sequence.
ACCESSION   DADVXM010000157 DADVXM010000000
VERSION     DADVXM010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1776
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.168"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..159
                     /locus_tag="KB927_002633"
     CDS             <1..159
                     /locus_tag="KB927_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBB6841505.1"
                     /translation="RRNKFYRSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGIPA"
     gene            242..859
                     /locus_tag="KB927_002634"
     CDS             242..859
                     /locus_tag="KB927_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841506.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKFEQTFRSFLKNRVSQIFNLD"
     gene            1023..1355
                     /locus_tag="KB927_002635"
     CDS             1023..1355
                     /locus_tag="KB927_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841507.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
BASE COUNT          628 a          225 c          361 g          562 t
ORIGIN      
        1 cgacggaata aattttatcg aagtctccgg actgcctcat ccacgattaa ggggatggag
       61 accattcgag gaatatataa aaagaaccga agaaatggaa cgctcttcgg cttttcggtg
      121 tctactgaga tcaaggtatt aatgggaata ccagcctaag atatttggag ttcagagagg
      181 gcgcgtttga ttttcaaact tcgcaacaga accattattt taaagtggga ggaaaattgt
      241 tttgtggata tttaaacaag aaatctttgc taaattattt agtttagatg gattaggttg
      301 gggaatctta ttttttattt ttttattttt aggatctatg tggatctggt ttgttgataa
      361 aaaaaattct tatgagaaag taatagtgaa aaaaatgaat cgaaatgaat tcgatgattt
      421 ttcaaaggaa catagagttg aattgtacga tagtcatgaa attaacagta cttctccatc
      481 ttattattgg gtatttggtt gcgaagaaaa accattggag attaaattgt tgaaaatgct
      541 tgaaaatcct ccagtcattg aagatttttc tgcaaaaaac gttgaaaaac agatgtttga
      601 acaggtacaa ataagaggtc aaaacaaaat ttcattagaa ccagatgaat atgcagcctt
      661 ttttttagaa acaaattcag gtacttcaat gcctgttttc aaagttaaat taaaaatgaa
      721 tggtcgttta tgcacttatg atcttgttgc aaatatgcgc tatggttcta ctggtgatag
      781 acgtactatt ttaaaatttg agcaaacctt tagaagtttt ttgaaaaata gagtatccca
      841 aatttttaat ttggattgaa aaaattaaaa atttggccaa aaatactaca gttttttaga
      901 gcaatcatct tatgatgatt gctctttttt tgttgttttt gtgtcattcg ttgttcaaat
      961 cctctattcg taaaataaat attttaaact agaaatatgc cttattttta ggaggaatca
     1021 aaatgaacaa tagagaaata ttggcaaaag aaatggcgga tttgaaagca aaagaagcga
     1081 agattagagc gaaacgaaaa cagattagac agaaagaaat gatttcttta gcgaaattat
     1141 attgtaaaaa ggaaggcttt aagacacctg ctgaagcatt agattttttg gaatcaaata
     1201 aaagaaatca ttcagtaaat gatgaggttt tagtatcgct aagaaaattt gcagatggat
     1261 tagtttggca agaaaatggt gcatattggc gtacgaatga tgttaagggt ttgactcaat
     1321 ttatggcaca atttcgttca gaaaatgtga actaaattga ggaggggttg aagtgaaaag
     1381 caatactttt cacttttggt tttttgcgga ataaaaattg tgaaaacaat gacgcaaaaa
     1441 gccaatggtt ttgaacgaaa aaaggacgta aaaaaggaat gcgaaggcag tcgtttttcg
     1501 ttcgcttttt cgtttgagag aaacggagtt tctcatcggc tgttaagccg atatagccct
     1561 cggcagagct tacagacttt acgcagtata agtctagtaa gttatacctt acatggaggt
     1621 ttttccgaat ttagcttgtg attctcgcaa taattttaac gaaaggaagt acacagttat
     1681 ggcctatatg gtggcacgaa cacaaaagca taaagttggg tcgttaaatg gacttcaaaa
     1741 tcatgtagat cgtaaaacga aaaatcatac gaataa
//
LOCUS       DADVXM010000158         1754 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.169, whole genome shotgun sequence.
ACCESSION   DADVXM010000158 DADVXM010000000
VERSION     DADVXM010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.169"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            120..992
                     /locus_tag="KB927_002636"
     CDS             120..992
                     /locus_tag="KB927_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6841508.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(1226..1584)
                     /locus_tag="KB927_002637"
                     /pseudo
     CDS             complement(1226..1584)
                     /locus_tag="KB927_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179228.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1655..>1754
                     /locus_tag="KB927_002638"
     CDS             1655..>1754
                     /locus_tag="KB927_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBB6841509.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQE"
BASE COUNT          544 a          309 c          376 g          525 t
ORIGIN      
        1 ttcaaaaaga aaaaatagta gttatttact tgtcatgtta ctaaataaaa aaataattta
       61 aatatgatat atagtcattt atttagtgat ttcattctaa aataaaggga gaaatgtcta
      121 tgctatacgg tgcaattgaa gcaggcggca caaaatttgt gtgtgccatt ggcgatgaag
      181 aaatgacgat caaggaaaga gtgagctttc cgacaacgac acctgaggaa acaatgcctt
      241 tagtcattga cttcttcaaa caataccaag cagatttagc aggaattggg attggctcat
      301 ttgggcctat cgatatccat cgcgattccg ccacttatgg gtacattacc tcgaccccga
      361 aattggcatg gcaaaatttt gatttcatcg gtaccatgaa aaaagaattt ccgatcccga
      421 tttcttggac aacagatgtc aatgcggctg cctatggtga gtatgtcttc ggcagtggca
      481 aaggattgag cagtgtcgtt tactatacga tcggtacggg tgttggcggc ggtgccttac
      541 aagaagggcg ctttatcgaa gggtttagtc atccagaaat ggggcatatg ctcgtcgtcc
      601 ctcatccaaa agatgacttt gctggcagct gtccatttca tggcaactgt ttagaaggga
      661 tggccgctgg acccgccatc gaaaaacgct tagggaaaaa aggacaagag gttgcagaag
      721 atgatcctta ttgggaaatc gaagcctcct atattgctca atgtgcctac aatacaacct
      781 tgatgttttc tccagatgtg atcatttttg gcggtggtgt gatgaaacaa cgccatatgc
      841 tgcaaaacgt ccacgacgca tttgcaaaat tggtcaatgg gtatgtcgaa acacctgagt
      901 taagcaaata tatcgtgacc ccagcattag aagacaacgc tggaacgctc ggttgtttgg
      961 cattggctcg agaagcggtc ttacattcat aaacgaaaaa aggctcttcg acatttagtg
     1021 ttggtagaga aagatacaac tgaaaattta gtcataacca gttaggcaga gtgcttaact
     1081 ggtttttgtt ttacttggaa gatcaagcct tgaatgagat aaattcttgc tcgaaagtta
     1141 tggaaatttc gatagccgta ggctacttgt attgtgcaat agttttttac aaaaaaaagg
     1201 ggtgcggata tttttttgga cctttttaac aaatatatct ttgcttcttc cgatattgaa
     1261 gagggcttag ccctcctaaa gataacttaa ttcgttgatt attataccaa tgaatataat
     1321 tatccaattt gtttataaac tgattgattg ttgtattctt ccagtcacgt tgataaaaca
     1381 tctcgttttt taatcgtcca aagaaacctt cgcacgctga attatctggt gaataaccct
     1441 ttttagacat agagtgaagc aagttgtctt tgttccaata gtccaactaa caatagcacc
     1501 atcgtaacaa tcgacaagtg gtgataagta gattttccct gcgggaattc taaattcagt
     1561 aatatctgtt aaccattttt ggttctgttg caaagtttta aatctactat caaataaggt
     1621 agaataatag aaaaagatag caggaggaat gacgatgaat cattttaaag gaaagcaatt
     1681 tcagcaggat gtgattattg tagccgtggg ctactatctt cgttataacc ttagctatcg
     1741 tgaagttcaa gaaa
//
LOCUS       DADVXM010000159         1753 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.170, whole genome shotgun sequence.
ACCESSION   DADVXM010000159 DADVXM010000000
VERSION     DADVXM010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1753
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.170"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            85..687
                     /locus_tag="KB927_002639"
     CDS             85..687
                     /locus_tag="KB927_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6841510.1"
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQNKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGLSDKEVEEQTGINRRTFRRYRQRCGISVADRPLD"
     gene            760..1149
                     /locus_tag="KB927_002640"
     CDS             760..1149
                     /locus_tag="KB927_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841511.1"
                     /translation="MKKLFANEKIDLLYSIILVLIWIIFLLISKLLHFHSEWVISFIG
                     VFVMGCINLPTILRRKKQYKKIDELRKVLNLSIKEVREIADIGRYDLSDWNWDKAHIS
                     PKKLYLLEDTLEKMYVKQFGKEFEMRK"
     gene            1322..1648
                     /locus_tag="KB927_002641"
     CDS             1322..1648
                     /locus_tag="KB927_002641"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841512.1"
                     /translation="MALSQVCMVSFLQRFLGSTYRNYFIVVFWLLLSLIAFIVFVFNF
                     ESLWQDIAYWIVPSKDLYINKPEIIRDLIKVVPMIILGIVVFVIGIRQGLKNYYGDYS
                     GDTKQQ"
BASE COUNT          618 a          223 c          364 g          548 t
ORIGIN      
        1 tttctgataa gcaatttgaa attgaaaaat tagatatatc tgattggtta ttgcaaccga
       61 gagaatttta gaggttggtt gaaaatggcg aaaattggtt atgcacgtgt cagtagcaaa
      121 gaacagaact tagatcggca attgcaagcg ttacagggcg tttctaaggt cttttcagac
      181 aaattaagcg gtcaatcggt cgaacgtcca caattacaag ctatgcttaa ctatattcgt
      241 gaaggggata ttgttgttgt tactgaatta gaccgcttag gacgaaacaa caaagaatta
      301 acagaactga tgaatcaaat tcaaaacaaa ggcgcaaccc tggaggttct aaatttaccg
      361 tcaatgaatg ggattgaaga tgaaaattta agacggctga ttaataattt agtgattgaa
      421 ttgtataagt accaagcgga atctgaacgc aaacgaatta aagaacgcca agcccaagga
      481 attgaaattg ctaagaaaaa aggaaaattc aaagggcgac aacctaaatt caaagaaaat
      541 gatccacgtc tacaacacgc ttttgatttg tttttgaacg gtttatctga taaagaagtt
      601 gaagaacaaa ctggaatcaa tcggcgaacg tttagaagat accgacagcg gtgtggcatt
      661 tcagtagctg atagaccttt agattaatat gaacgtggtg aagataacat aaaagagaaa
      721 acaagaaagt aatagtaata gaaatgaggg gtagacatta tgaagaaatt gtttgcaaat
      781 gagaagatag accttttata ttcaattatt ttagttttaa tttggattat tttcctactt
      841 atcagtaagt tgcttcattt tcactctgaa tgggttattt cttttatcgg agtgtttgtt
      901 atgggatgca tcaacttacc aacgatttta cgaaggaaaa aacagtataa aaaaatagat
      961 gaactaagaa aagtgttaaa cctatccatt aaagaagtaa gggaaattgc cgacattggt
     1021 agatatgatt taagtgattg gaactgggat aaagcgcata tttctccaaa aaaattatac
     1081 ttactggagg acaccctaga aaaaatgtat gttaaacagt ttggaaaaga atttgaaatg
     1141 agaaagtagt tttttaagga aatattccaa gtggaggtat tcaaagctat tcaagatcga
     1201 aagattcttt tggttatatt tttgttggtt ctgattgtca gtgtggtgtt aatcattggt
     1261 agttttaaaa taaggaaaca aagtagggga acggctttat ttttgctttt attgggaata
     1321 gttggcatta tcgcaagtct gtatggtttc ttttttacaa cgttttttgg gatcaactta
     1381 taggaactat tttatcgttg tgttttggtt attgctgtct ttaattgcgt ttattgtttt
     1441 tgtatttaat tttgagagtt tatggcaaga tattgcttac tggattgttc caagcaaaga
     1501 cctttatata aacaaacctg aaatcataag agatttaatc aaggttgttc caatgattat
     1561 tttaggaatc gtagtttttg tcattggtat tagacaagga ctgaaaaatt actatggcga
     1621 ttattcaggt gacacgaagc aacaataact aaagctatct aaaattagga aaaaaggaga
     1681 gaatgaatga gtacagttat tttagctgaa aaaccaagcc aggcgttagc ctatgcccag
     1741 gcatttaatc aga
//
LOCUS       DADVXM010000160         1665 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.171, whole genome shotgun sequence.
ACCESSION   DADVXM010000160 DADVXM010000000
VERSION     DADVXM010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.171"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            132..506
                     /locus_tag="KB927_002642"
     CDS             132..506
                     /locus_tag="KB927_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6841513.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="KB927_002643"
     CDS             complement(620..1249)
                     /locus_tag="KB927_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6841514.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="KB927_002644"
     tRNA            complement(1383..1455)
                     /locus_tag="KB927_002644"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          558 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga taacgaatat taatgtattt
     1501 gtcaacagaa ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa
     1561 ataaaaataa caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa
     1621 agtattgcgt tatttagaag aaattgatat tatattcatg tactt
//
LOCUS       DADVXM010000161         1656 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.172, whole genome shotgun sequence.
ACCESSION   DADVXM010000161 DADVXM010000000
VERSION     DADVXM010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.172"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(52..1518)
                     /locus_tag="KB927_002645"
     CDS             complement(52..1518)
                     /locus_tag="KB927_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBB6841515.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          560 a          338 c          296 g          462 t
ORIGIN      
        1 aaaaaacagg aactgctgca aataagcaat tcctgttttt atgttcattg attaatgaat
       61 agagcccatt agttttttga ttggttcttt cacagtaaat agcaagatac caccgacgat
      121 tgctactgca ccgataatac cgaagtaagc agattctgtt cccggtgtgt agaagcgtgc
      181 aatttgtgca ttgattgctt gtgaagaagc atcagctaag aaccaaatag cgattgtttg
      241 tgattcaaat gctcgtggtg ctaattttgt tgtcacagac aaaccaactg gtgaaagaca
      301 caattcagca ataaccacga tgaagaaact tcccaacaac cacaatggac ttacttttcc
      361 acttgtacca taaagcatac ccggcaacat caatagcaag tacgataatc ctgcaaataa
      421 aagtccaaga gagaatttca ctactgtaga tggttgacgt tcaccaagtt tcgtccacat
      481 cgttacgaat actggtgtca gaataaagat gaaaattgga ttcaatgatt gataccagct
      541 tgcttggatc gttacaccaa atagcgtaga ttgtgtacgt tcactagcaa ataaagctaa
      601 gatagatgaa ccttgttctt gtaatgacca gaaaatgatt gctgcaagga ataatgggat
      661 ataagcccat actcttggtt tttcttcagc agttacatct tttgaagtca gcattttgat
      721 aaagtaatac aacggtaaga taatccccaa tacactgatt gtattgacaa aaaagtcaat
      781 tgtcagatga ccagttagtt gtgccccgcc gaatactgca gcgataacaa caagtgcgat
      841 gatcaagtta cggatgaatc ctttacgttc ttcagttgtc aaaggattcg gcggtgttgt
      901 acccactccg tctaatgtct tgcgtccttg gatgatgtat tgtaataatc caaagaacat
      961 cccaatagca gctaaagaga accctaaatg atagttatat tcttgaccga ttgtaccaac
     1021 gattagtggt gctaataatg cccctaagtt gacacccatg taaaaaatcg aaaatcctgc
     1081 atctcttcgc aagtcagtct ttgaataaag atgtccgacc atgccagaaa catttggttt
     1141 caaaaaggcg gttccgataa taatcaatgc catcgaaaca aacaatgtac ttacaccaaa
     1201 tggtaaagcc aagacgatgt ggccaagcat aatgaaaact ccaccgaaga atacagtgcg
     1261 ttttgctcct aacactcggt cagataccca tccgccgacg atactagaca tgtagatcaa
     1321 agatccgtag atcgacatga tagctaatgc tgttgctcgt ggtaatccaa gtcccccgtt
     1381 ggcaactgta tcgtacatat aatagataag taatgcacgc ataccgtaat aactaaatcg
     1441 ttcccacatc tcagtgaaga acaaagttga caatcccttc ggctgcccga agaagccctt
     1501 gtcttgctgt ttttccataa tctatacccc aattctttaa attttcagaa aatattatac
     1561 atctttaccg aaaaatttaa ctaaaaaact tatttaagaa atataaacta attttctata
     1621 aaagcaagta atttttaatg gcaatatcat aaaaaa
//
LOCUS       DADVXM010000162         1604 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.173, whole genome shotgun sequence.
ACCESSION   DADVXM010000162 DADVXM010000000
VERSION     DADVXM010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.173"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(1..81)
                     /locus_tag="KB927_002646"
                     /pseudo
     CDS             complement(1..81)
                     /locus_tag="KB927_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
     gene            430..1515
                     /gene="xerS"
                     /locus_tag="KB927_002647"
     CDS             430..1515
                     /gene="xerS"
                     /locus_tag="KB927_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBB6841516.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT          610 a          275 c          218 g          501 t
ORIGIN      
        1 taaaaaaatt gtatctccag gatgcaaccc attttcttta agaaattcct tttaaattgt
       61 taatactact gagtgcccca cttctctgaa ttttctttaa cttctccctc ccctttttta
      121 tttgtatata cattcatata cgcttgttaa tatcaaatca accgtagtct ctcttatgtc
      181 taattatata gaaagattgt tctttctata taatttagac aatttaaaaa attaagattg
      241 cctccttctg tttcctttcc tattcatgta taccatttat tttaaattat taaatctata
      301 cctatttatc tgcttttttg aaataaatta ataaatttca aagtatacca attgacaaaa
      361 cactctataa ttggtatagt ccaattatag agatactcct ctcccctact tatcgaaagg
      421 atgaataaca tgaaaaatac agaaatatat caaaaaatag atacaatcat acttcatatg
      481 cccgattata taaaagattt tgttcaagat cgtgaggata aagatcaatc acctcgaact
      541 actttagaat atctaaaaaa ttataagctc ttttatgaat ggcttctgag tgagtctatc
      601 gttcccgata cttcaatcac ctcgataaga cagttaactg cctatgatct aaacttgtac
      661 aaatctcatt tgaaacgtcg cacaaaggaa aatgtaaaaa aagagacaac aaaaactaag
      721 ctcaaagata ataataactt aggtctatct acttctacta tcaatagaaa tatcacagca
      781 ttaaaggttc tatttaaata tctttcgaaa agttccaata atcctttagg aaaaccatac
      841 ttagaaaata atcctatgga tcaagtagca actatcacag ataaaactac gttagctgcc
      901 cgtgcaaacg caatcgagaa aaaattattt ctagacgaag atacacaaaa ttatctagat
      961 tatattgcca atgaatataa aaaaactttg agcaaacgag ctttgatcta ttatcaacga
     1021 gatgtagaaa gagacctggc gatcaatgca ttgattttag gatctggatt aagactctcc
     1081 gaggttgtaa atattaattt agaggaccta tctttagaaa agaataatgt ggtagtaact
     1141 agaaaaggaa ataagagaga cgcagtaaat atagcagcat ttgcaatgga atatttagct
     1201 aattatctag ctattcggaa agaacgatac aaagtaacag aaaacgaaaa agctttattt
     1261 ctagcaattt atcaaggaga agccaagcgt atatccggta ttgcaatcga acggatggta
     1321 gcaaaatatt caaaaggatt cagagtccaa gtcagtccac ataaattacg tcatactttg
     1381 gctactagac tctatcaaca gacaaattca ttggtattaa ctgcccaaca attgggacat
     1441 acaagtacaa atacaacaac tttatatact catatagaca atgcagctac aattgatgct
     1501 ttgaacgctt tgtaaatgta gtaaaaaata gtataataat gaagcctgtc tctaaaatta
     1561 gataaaagcc caactttaaa ggcaagcttc attatcattt ttat
//
LOCUS       DADVXM010000163         1496 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.174, whole genome shotgun sequence.
ACCESSION   DADVXM010000163 DADVXM010000000
VERSION     DADVXM010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.174"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..613)
                     /locus_tag="KB927_002648"
     CDS             complement(<1..613)
                     /locus_tag="KB927_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6841517.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFL"
     gene            901..>1496
                     /locus_tag="KB927_002649"
     CDS             901..>1496
                     /locus_tag="KB927_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6841518.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKK"
BASE COUNT          526 a          216 c          282 g          472 t
ORIGIN      
        1 gcaggaagta ttgagttagt ttgtaaagtc tgcgatcttc aaggatcgta aatagctgat
       61 gggttgtccc atcaacacaa ataaaactca tggaaccaga aacagacttc attgatttga
      121 actcatccat acacaacacc gtcggaagga agttcatacg tggctggtaa tgcttcgttg
      181 cttcacgcaa gatccgtgtc accgtcccat ccgagacgaa gtacttctta gcgattagtt
      241 tacgtgattg attttcgtac agttctatga gaatcgcctg cttcagttcc tttgttagtt
      301 gatgatgttc atcaactaag tccgttttcg cagaaaaggt ctgcccacaa tcatagcata
      361 gaaaacgggt acgttttaat tctaaaatag tcaacttttc tttgactttc aatatctgag
      421 tacgtgtcgt ataggaaccg ttgcggataa tacgaatcga tccacagtgt tcacaatggg
      481 aaggtgagtc atccaatctc cctttaataa actgcgcttg aacgccttta tattcttttt
      541 caatcagcca ttcttcatca aaaaataaat gtttatctgt taatccgagt aattttctag
      601 tatgattatc catagagcga ctcctttggt agggtgatgt tttggtcgac taaattttac
      661 caaaagtgag tctctttttg agttgaaacg aagaaaaagt gttagtagaa aatcgccttc
      721 gattttccaa caacacaaaa tattatagaa ccctttattc taaaggattt caaggtgtct
      781 gtttgcattt attaaaaaaa agaaaaagta ttggcaacag aaggcgtcac caacactaga
      841 tattatagag ccataatatg ctgtataata tctagtgtat aggcttaagt ggaggtatat
      901 atgaaaatat taactgttga agatgataat atgataagag agggaataag tgaatatctt
      961 tcagaatttg gatatactgt tattcaagct aaagatggaa gagaagcctt gtcaaaattt
     1021 aatagcgata taaatttggt tatcttagac attcagatac cttttataaa tggtttagaa
     1081 gtgttgaaag aaattagaaa gaaaagcaat ttaccaattc taatcttgac tgcatttagt
     1141 gatgaagaat ataaaattga tgcatttact aatttagtag acggatatgt agaaaagcca
     1201 ttttcattgc cggtcttaaa agctagaata gattctttaa ttaagaagaa ttatggacat
     1261 ttagagaagt ttgaatataa ggatctatcg gttaatttta atagctatac agctaaaata
     1321 aatggtgaag aaatagatgt aaatgcaaaa gaactagaag tattaaaatg tttattggat
     1381 aataatggac aagtgttaac aagaatgcaa attattgatt atgtatggaa agatagcgaa
     1441 gaaactcctt atgatcgagt aatagatgta tatataaaag aacttagaaa aaaatt
//
LOCUS       DADVXM010000164         1479 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.175, whole genome shotgun sequence.
ACCESSION   DADVXM010000164 DADVXM010000000
VERSION     DADVXM010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.175"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            28..987
                     /locus_tag="KB927_002650"
     CDS             28..987
                     /locus_tag="KB927_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6841519.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            1120..1326
                     /locus_tag="KB927_002651"
     CDS             1120..1326
                     /locus_tag="KB927_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBB6841520.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
     gene            1337..>1479
                     /locus_tag="KB927_002652"
     CDS             1337..>1479
                     /locus_tag="KB927_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6841521.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQ"
BASE COUNT          517 a          234 c          292 g          436 t
ORIGIN      
        1 ccaaagaatt ataaggagtg agtacaaatg acctataccc atcttacaac ggatgaactt
       61 gtaataatag agtcttattt caaaatgaat caatctgttg ctaaaactgc ccattgcttg
      121 aatcgttcaa gacaaacgat ccataaagta tatctgttct tcaagcaagg aaaatcagcc
      181 ttagaatatt atcaacagta taagaaaaac aaatcaaact gtggtagacg tccgcttgtt
      241 ttacccgagg aacaatcaga atatattcaa agaaaggttg ttcaaggatg gacacccgat
      301 gtgattgttg gtcgtgcagc gtttcctatt agttgttctg ctcgtaccat ttatcgtatg
      361 ttcaaaaagg ggctatttga ttcttctgac ttaccgatga aaggcaagcg taaaccgaat
      421 ggacatcaag aaagacgtgg aaaacaaact ttccgccgct ctattcatga acgtgaaaag
      481 gattatagcc aattctcaaa tgagtttggt caccttgaag gtgacactat cgtaggtctg
      541 aaacataaaa gtgctgtaat taccttagtt gaacgattat caaaagttat catcacattg
      601 aaaccgtgtg gtagacaagc gattgatatt gaaaaaaaat taaatcaatg gtttgaatct
      661 gtaccgaaaa acctattcaa atccatcact tttgattgtg gaaaggaatt ttcaaattgg
      721 aaacagatca gtaatgtcaa tgatattgcc atttatttcg ctgatccagg aacgccgtct
      781 caaagaggcc taaacgagaa ttctaacgga ttgttacgta gagatggttt attgaaatct
      841 atggatttca attcagtaga tgaatttttt attcaatctg tcgcatctaa acgaaataat
      901 attcctagaa aatcactgga ttatcgaaca cctttggaag tatttttgag ttacgtaagt
      961 attgatgatc tgtctaactt aatttgacaa ttaagaaaga taaaattgaa caactggacg
     1021 ggcaaattga tgccttgctt tcagaaagag aaatattgat agaagaaaac aagcgattga
     1081 aaaagaaagt agcccaacca atgaagggag gtggatagta tgaacaatag aacctttgat
     1141 attttgaaat ggatcgctat agtagttatc cccgctttag cgacttttgt cggtcttgtc
     1201 ggaaaaggtg ttaactggcg gtacacagat ataacggtga tgattattac aggttttgga
     1261 gcatttctag ggagtatttt aggtgtatca aatcgaacgt ataagaaaat ttcatcagat
     1321 aaataggagg atagatatga aaaagaaaat tactattact gcgatgagcc tgttaacggc
     1381 tcttttttta ttgccaatta acggatttgc ctatactatc aacaatgaat ttaatttggg
     1441 cgcaaatgaa ggtagctcac aagtagcaaa taatcagta
//
LOCUS       DADVXM010000165         1426 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.176, whole genome shotgun sequence.
ACCESSION   DADVXM010000165 DADVXM010000000
VERSION     DADVXM010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1426
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.176"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            41..451
                     /gene="spx"
                     /locus_tag="KB927_002653"
     CDS             41..451
                     /gene="spx"
                     /locus_tag="KB927_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBB6841522.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            465..821
                     /locus_tag="KB927_002654"
     CDS             465..821
                     /locus_tag="KB927_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBB6841523.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          524 a          210 c          267 g          425 t
ORIGIN      
        1 ttactgtaga attggattat aattaaaaag gagtgagaaa atgataaaag tatatacttc
       61 gcctagctgt acttcctgta gaaaagcaag agcatggttg caagcgaatc aacttgaatt
      121 tgaagagaag aatatttttg ccgaaccgtt aacagaaagt gagatcaaaa agatcttggc
      181 agcgactgaa ggaggagttc aagatattat ttccactcgg tcgaaaattt acgaaaagct
      241 gggcatagat tttaacgaat taactttaaa gcaaatgatc gtcttattca aagaatatcc
      301 ttcattattg agacgaccta ttttgattga tgaaaaaaga atactaatcg gatttaatga
      361 agatgagatc cggtcatttg tccctcgtga aattcgatgt gttgccagaa atctgatcta
      421 tttacaaaac aataacatct taaattcata gggagggagc cttcgtggaa gtgaaagtct
      481 atggatcagc gcactgtgta acaagtctga aggcgaaaca atggttagaa caccatcaat
      541 tgccttatca atttgttgac ttagaagaac gcgatctaag tacagaagaa gcagaagaat
      601 tatgcagttt tgaagaagtg caagcagaac agctatttgc gacttggtct gaggcttttc
      661 acaacattgc gattgacctt tcctgtgtag gaaaaaaaca actgattttt ttatgcacac
      721 aacataccaa tctcctcaga cgtcctttga ttattatcga tgaagttcta tttattggat
      781 acaatgagca gttgatggaa cagcttatct taaataaata gactttaact gttttaatca
      841 agtcactgag catttcatac agttgtaaca gtcgaacact tagcatcaag cgtgttatgt
      901 gttctttttt tgactttatt tttctactat agagacatgc tcaatttatg tggtcaaaat
      961 tcaaatctag gtggggatat agagttaaaa atatattgac atgtgtaaat ttacatgata
     1021 tattcatttc tgttgtttta agtagcaaag caataaaata gtattttaaa aaacatataa
     1081 aatagttgtt gacatgttag aaatgacatg ataagataac tgagttgtta aaaaagaacc
     1141 acttgtgaag cttgattcta tcgaaaaaaa cttcaaaaaa gttcttgaca aataacaaat
     1201 gataagttat gataaatgag ttgctgtaag atttcgaaaa acgaaatcaa aaaaactttt
     1261 aaaaaagagt tgacaattac ttgtctctct gatatgatat aaaagttgct acggcagcca
     1321 aaaacgaatc ggggaacact cctgatgaag tagacctttg aaaactgaac aaagtaagac
     1381 aaaccaaatg tgtagggcgt cttgattcaa ttcaagacaa caaaca
//
LOCUS       DADVXM010000166         1420 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.177, whole genome shotgun sequence.
ACCESSION   DADVXM010000166 DADVXM010000000
VERSION     DADVXM010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.177"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="KB927_002655"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="KB927_002655"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBB6841524.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTITPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          496 a          184 c          236 g          504 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtca ctattactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctggactaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta acttattgct tttgcaaaat ttatttacct gttttctgga tcaacgatag
     1141 tgtatattat gctatccttg tttggatttt aggacgttta aagaggcact tttttacata
     1201 acttaatcca tagacctttt aagcatgctg tgagataata ataaagaaga gtttaaagcg
     1261 caccccaaac cacttcccca taagtgtatt acgctttaaa ctcttttata tttgaattca
     1321 ctaagaagca taccatattt ttgaaaaaaa gtgagaaaaa aggcttataa ttaggattta
     1381 gagtaattaa ttagatgttt attttatagg actgatacta
//
LOCUS       DADVXM010000167         1407 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.178, whole genome shotgun sequence.
ACCESSION   DADVXM010000167 DADVXM010000000
VERSION     DADVXM010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.178"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            360..902
                     /locus_tag="KB927_002656"
     CDS             360..902
                     /locus_tag="KB927_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841525.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFKKNTSEEKNLKL"
     gene            1058..>1407
                     /locus_tag="KB927_002657"
     CDS             1058..>1407
                     /locus_tag="KB927_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBB6841526.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          551 a          171 c          269 g          416 t
ORIGIN      
        1 ctgcgcgagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt gacatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcaa attgatgaag cagttcccaa
      181 agggctgctt catcaatttt ttcgtaagtg tccgtacact tactgtgctt gctcatatat
      241 taatcgatca tatactaatc gtgtaagaac aactttaagc ataatactta tattgttata
      301 ccatagtttg gaaaaataaa aaattatatt tcatcaacgt ttcataaaag gtgtgtagaa
      361 tgttattgaa agtagctata aaatgctatt gtgtaaaaaa taaaggagga ataatttatg
      421 aaaaaatagt accaagagga gcatgcctat tacttgcatt atgtttgagc ttaagcgcag
      481 ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga aggacaatcc ataagttctg
      541 aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga aacttttaag ccatcagatt
      601 atacattgga ggcaaagaaa gaatatgttt atgaatattt agggcttaaa tttaaactct
      661 cagacaaatt tagaaattat atagctgata aaaagatagc gatgttagat gatcaaagtc
      721 ctatagataa agaactaaag tatgctattt tgacatttga gaaaatgaca gaagaacaaa
      781 agaatgcagt tatagaaaag atgggcgatg gatataaaaa ttggcaaaat gagcttgaaa
      841 gaattgggac tattggtata tttaaaaaaa atacatcaga agaaaaaaat ctaaaattat
      901 aaaatgtgat actcatacta aaataggagt ttcaagtgat ggaaaatacg attgctattt
      961 aagcacaaat agcggagctg aaagtaatct tctggatgaa ttaaaaagaa ctgagattca
     1021 aattatagat aaaaaagaac gtcctaaaaa tggttttgtg ctatcagaaa aaactgattt
     1081 agaaaataca gaagcattta acaaagaatc ggttaaagat ttacgtaaac taccaacaaa
     1141 ggacataaat ggcaaggatt ttacaagtaa agattttgag aagtatgatc ttactatggt
     1201 aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa attcctgatt tggttgaggt
     1261 tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga gttgttacag atcctgttga
     1321 tgataacggt gaaaacaagg aagcaattga aaagtcaaag ttaatacatg aaaagacaaa
     1381 ggcttcatat cctttcttaa tgccaga
//
LOCUS       DADVXM010000168         1337 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.179, whole genome shotgun sequence.
ACCESSION   DADVXM010000168 DADVXM010000000
VERSION     DADVXM010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.179"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..1337
                     /locus_tag="KB927_002658"
     rRNA            <1..1337
                     /locus_tag="KB927_002658"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          358 a          293 c          406 g          280 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc catttcttta agaaagtaag atccctgaga
     1261 gatgatcagg tagataggtc aggagtggaa gtacagtgat gtatggagcg gactgatact
     1321 aatcgatcga ggactta
//
LOCUS       DADVXM010000169         1306 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.180, whole genome shotgun sequence.
ACCESSION   DADVXM010000169 DADVXM010000000
VERSION     DADVXM010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.180"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..891
                     /locus_tag="KB927_002659"
     CDS             <1..891
                     /locus_tag="KB927_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBB6841527.1"
                     /translation="VSVPLILNKREKNNLKKKMLIPFDSEVKGLLNKLTISNIDSTRE
                     KIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITEEKEQQKAIKEQMIE
                     EEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKELYANKIQELEEKLKE
                     LEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEPMDRIKELSSASVPF
                     EFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLDEIEKVVLENYNGTV
                     TFTKLAKAEQYRRSLELSKD"
     gene            963..>1306
                     /locus_tag="KB927_002660"
     CDS             963..>1306
                     /locus_tag="KB927_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841528.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQ"
BASE COUNT          573 a          153 c          210 g          370 t
ORIGIN      
        1 gtttctgtcc ctcttatttt aaataaacga gagaaaaata atttaaagaa aaaaatgctc
       61 attccatttg attcagaagt gaaaggatta ctcaataaac taactatttc taatatagac
      121 tcgactaggg aaaaaatcat aaaaatattt gataaaatta ataatttatt caagaatgac
      181 aatgctgaat taaggaaggg tcttttagag tttaaacttc aagaactaga acttcattac
      241 tcttatttag tgaaaattac cgaagaaaaa gaacaacaaa aagcaataaa agaacagatg
      301 atagaagagg aaaaagttcg tagagaaatt gatcgtgaaa agaaacgtat tgataaagaa
      361 caacgtcaat tcaattctga aatttccaaa ttaatcgcat atatgcaaaa agctaatgca
      421 gatgtggaaa aagaattata tgcaaataaa attcaagaac tggaagaaaa attaaaagaa
      481 ttagaagtta tacgtgaaaa tgtattacaa agagaattaa atactagagc cggttatgtg
      541 tatgtaatta gtaatattgg gtcttttggt gaagacatat ataaaattgg tatgactaga
      601 agattagaac ctatggatag aataaaagaa ttgagtagtg catcggttcc atttgaattt
      661 gacgttcatg cgatgatttt ttcagaggac gctccgtctt tggaaactaa attgcataat
      721 cattttagaa aacaagaagt taataaaatt aatcaaagaa aagaattttt caaagtttca
      781 ctagacgaaa tagagaaagt tgttttagaa aattataatg gaacagtaac atttacaaaa
      841 ttagctaaag ctgaacaata tagacgatct ttagaattgt caaaagatta aatatataaa
      901 aagccttcgg gctttttctt ttaacaatta ataggaacgt atattcgaaa ggaatagaaa
      961 taatgtggtt agaaaaaata aatgacaaaa aatttaagta caccgaacgt tatacggatc
     1021 ccttaactga aaaaaagaga aaagtgtccg ttactttatc tagcaattca cgccaagctt
     1081 ggaatcaagc taacttactt ttgaatgaaa aaatcgcaga aaaaataaaa cgaaatgaag
     1141 aattaccact aacttttgga gaattaaaaa ctaaatggga tgaaaaatac aagccaactg
     1201 taaaagaaag ttcctatcga acaactcagg tttatctatc attaatttca aaatatataa
     1261 aagatgatgt acttgtaaaa aacgttaata gtaatcttat acaaga
//
LOCUS       DADVXM010000170         1257 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.181, whole genome shotgun sequence.
ACCESSION   DADVXM010000170 DADVXM010000000
VERSION     DADVXM010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.181"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            29..1159
                     /locus_tag="KB927_002661"
     CDS             29..1159
                     /locus_tag="KB927_002661"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBB6841529.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKE
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
BASE COUNT          458 a          207 c          245 g          347 t
ORIGIN      
        1 acaaaaaaca aagaaaagag tgagtgaaat gagcaaaaat agaccattta cagtagatca
       61 tgtcggaagt ttcttacgcc cgcaatcgat caaagaagca agaaaaaaag ttcaagaagg
      121 cttactttca aaagaagaac ttcgtgcaat cgaagaccag gaaataaaaa aattagtgga
      181 agaccaaaaa gcagtcggca tcaaaggaat tacagatggt gaatttcggc gtggattttg
      241 gcatcttgat tttttagaag aactaaatgg tatcgaaggc tatgttccag aaactggata
      301 taatcaaaca ttccacggaa aagcagcacc agcttataat attcgggtag tagataaatt
      361 atctttcaat ccaaatcacc catttttaaa agattttgct tttctgaaag aagtagtgga
      421 aacagatgat acttttgttg caaaagcaac gatccctagt cccacgatga ttttacgaca
      481 agagatccta tctaatgatg gttcttcaaa aatcaaggag atttatcctg atctatctga
      541 tttttatgag gacttgtcct ctacttacaa agcagcgatt catgcttttt atgaaaaagg
      601 ttgccgttac ctgcaattcg atgatacaaa ttgggcgttt ctagctgatc aaactaaaag
      661 agaagcactt cttcaaaaag aaattgatcc gaaagaaatg gcccatattt gtacagagat
      721 tatcaataac gcactggaag acaaaccaga agatttgacg atcacaacac atatctgccg
      781 cgggaatcac gcttcttctt ggctgttttc cggtggatat gaacccattg cagaagagtt
      841 gttttcaaca aattatgatg gtttcttttt ggaatacgat tctgaccgag caggagattt
      901 tactccttta agacattgga gtaacaaaga aagtaaagtt gttttaggat tagttacttc
      961 taagtttcca gatttggaag atacggagaa aataaaagaa cgaataaaag aagcacaaca
     1021 atttgtacca ttggaaaatc taagtatcag tcctcaatgt gggtttgctt caacagaaga
     1081 aggaaaccat ttaacagaag aagaacaatg gaagaaaatc caattattgc agcaagtcgc
     1141 aaaagaagtt tggctataaa aatgtgaggc ttggcaaaaa aaagcgtccc aaaaagtcgg
     1201 cttttcatgg agtggagaaa tccactcttt tttatttacc ttttatatta tttattt
//
LOCUS       DADVXM010000171         1245 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.182, whole genome shotgun sequence.
ACCESSION   DADVXM010000171 DADVXM010000000
VERSION     DADVXM010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1245
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.182"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            13..>1245
                     /locus_tag="KB927_002662"
     CDS             13..>1245
                     /locus_tag="KB927_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBB6841530.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGF"
BASE COUNT          414 a          247 c          242 g          342 t
ORIGIN      
        1 acgatacgct atatgaatga ttctatcaaa aaaatgctga gaataacaga gaaagatttg
       61 atgattacag aggtctctta cgagaccctt cagaagaaaa agacgttggt cgtcgatgct
      121 gttctctcgc ctactcctcg tgcttgtaga agttgtggtt ctactgtggt agatggaaac
      181 gggaaagcaa ttatagtgaa aaatggaaaa aaggaaacga ttgtccgttt tgaacaatac
      241 aatcatatgc ctttggttat gcgcctaaaa aagcaacgct atacctgtaa aaactgtcgc
      301 acccattgga cggctcaaag ttattttgtc caacccagac attcaatcgc aaatcatgtt
      361 agatataaaa ttgcttcttt actgactgaa aaagtatctt tatcttttat tgcgaaaagc
      421 tgtcaggtat ctttgaccac cgttattcgt acattgaaag agtttaaaag ctatttacca
      481 aagcaatcta agaagatcct ccccagagta ttgatggttg acgaatttcg ttcgcatgct
      541 tccatagaag ataagatgag ctttatttgc gcggatggcg aaacaggaaa attaatagat
      601 gttttgccta cgcgtaaatt acctcgatta acaagctatt tcttaggttg taccaatcca
      661 gaagaagtag aattcttggt gacagacatg aacgccgcct acttccagct caccaaacgt
      721 gttctgccaa atgcgaaagt cgtgattgat cggtttcata ttgtcaaaca catgaatcaa
      781 gcgttcaatg agttgcgtat ccgtgaaatg aatgaacttc gtaaagccgg acagaaaagc
      841 caggcagaaa aactgaaaaa gaactggcgc tttttgctaa aaaatcgtgc aaacatcaac
      901 cattatgaat acaaaacatg gaaaagtttc cgagcaccaa aatacccatt tcttactgaa
      961 gcaatgatga ttgatcgatt gcttgagttt tctccgcccc taaaggaggc gtatcccttt
     1021 tttcatgaat tagttgaagc ctttcgagac aaagaccctg acttattttt ctccttattg
     1081 gcagaacttc ccgaaacgtt agatgacagc tttcgggaaa agcttcaaaa ccttctgacc
     1141 tatgaagaag gcatcaccaa cgcaatgatc tatccttatt ccaatggaaa aatagaagcg
     1201 aagaataccc acataaagac aatgaaacga gtatcctacg gattt
//
LOCUS       DADVXM010000172         1236 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.183, whole genome shotgun sequence.
ACCESSION   DADVXM010000172 DADVXM010000000
VERSION     DADVXM010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.183"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..956
                     /locus_tag="KB927_002663"
     CDS             <1..956
                     /locus_tag="KB927_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBB6841531.1"
                     /translation="EAIITDLPDYIKRIDSDSFLAAFYLYTAKYWIDDSRKTIKYAKR
                     KKQLYFQTWHGTPLKKIEFDAKDKLPKRYLSYAKKDSESITYLLSGNRYSSKKYVSAF
                     NIVPSKILEVGTPRNDELASSKEQVFDLKKKQINVLFAPTFRNNIEDNGITQLEWLGV
                     DNLREFFKKQQQELNFMTKFHPNVHSKLATDSKSIEYMKKHQITLINDGIPLEMLFEE
                     IDVLITDYSSIFFDFALTKKPIILFNYDEKEYSLERGFYIQLSELPIISVQDSYGLVD
                     VFKNQQEKLLKSSQELLDYIGNYETGASTEKVLELIERDIK"
     gene            953..>1236
                     /locus_tag="KB927_002664"
     CDS             953..>1236
                     /locus_tag="KB927_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBB6841532.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFIQFLIGLSV"
BASE COUNT          458 a          157 c          203 g          418 t
ORIGIN      
        1 aagaagcgat tataactgat ttaccagatt atattaaaag aattgactcc gattcttttt
       61 tagctgcctt ttatttatat acagctaagt attggataga cgatagtcgg aaaacgatta
      121 agtatgcaaa aaggaaaaaa caactttatt ttcaaacatg gcacggaacg cctttaaaaa
      181 aaattgaatt tgatgcaaaa gataagttac ctaaacgtta cctaagctat gcgaaaaaag
      241 atagtgagtc aattacatat ttattatctg gtaatcgcta tagttctaag aagtatgttt
      301 cagcattcaa tatcgttcct tctaaaatat tagaagtagg aactcctaga aacgatgaat
      361 tagcctctag taaagagcaa gtgtttgact tgaaaaagaa acaaatcaat gtcttatttg
      421 ctccaacttt tcgaaataat attgaggaca acggaattac gcaactagaa tggttaggtg
      481 tggataactt acgtgaattt tttaaaaagc aacaacaaga attaaatttt atgactaaat
      541 ttcatcctaa tgttcatagt aaattagcaa ctgattctaa aagtatagaa tatatgaaaa
      601 aacatcaaat tactttaatt aatgatggga ttcctcttga aatgcttttt gaagagatag
      661 atgttttaat cacagattat tcatctattt ttttcgattt tgcgctaaca aaaaaaccaa
      721 ttattctttt taactatgat gaaaaagaat atagcttaga aagaggtttt tatatacagt
      781 taagtgagtt accaattata agcgtacaag atagttatgg ccttgttgat gtttttaaaa
      841 accaacaaga aaagcttttg aaaagttctc aagagttact tgattatatt ggaaattatg
      901 aaacaggagc aagtacagaa aaggttcttg agttgataga gagggatata aagtgaaaaa
      961 aacagtaaaa gatatatttt ataatgcgat atatcaagtc tttttgattg ttttaccctt
     1021 acttactata cctatactta gtcgtagaat tggttcaact ggtttaggga tttatgggta
     1081 tgttttctca atatcacagt ttttaatgac tgtcattgct gtgggaatga atccttttcg
     1141 tattcgaaat atcgctaaat caaggaaaga taaaaaagca ctatctttac aattctggaa
     1201 tatttacttt attcaatttt taataggctt gagtgt
//
LOCUS       DADVXM010000173         1188 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.184, whole genome shotgun sequence.
ACCESSION   DADVXM010000173 DADVXM010000000
VERSION     DADVXM010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.184"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            56..>1188
                     /locus_tag="KB927_002665"
     CDS             56..>1188
                     /locus_tag="KB927_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBB6841533.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQY"
BASE COUNT          424 a          183 c          246 g          335 t
ORIGIN      
        1 tatttatcac tgggattttt atgccctttt gggtttttga atggaggaaa atcacatgaa
       61 aattattaat attggagttt tagctcatgt tgatgcagga aaaactacct taacagaaag
      121 cttattatat aacagtggag cgattacaga attaggaagc gtggacaaag gtacaacgag
      181 gacggataat acgcttttag aacgtcagag aggaattaca attcagacag gaataacctc
      241 ttttcagtgg gaaaatacga aggtgaacat catagacacg ccaggacata tggatttctt
      301 agcagaagta tatcgttcat tatcagtttt agatggggca attctactga tttctgcaaa
      361 agatggcgta caagcacaaa ctcgtatatt atttcatgca cttaggaaaa tggggattcc
      421 cacaatcttt tttatcaata agattgacca aaatggaatt gatttatcaa cggtttatca
      481 ggatattaaa gagaaacttt ctgccgaaat tgtaatcaaa cagaaggtag aactgtatcc
      541 taatatgtgt gtgacgaact ttaccgaatc tgaacaatgg gatacggtaa tagagggaaa
      601 cgatgacctt ttagagaaat atatgtccgg taaatcatta gaagcattgg aactcgaaca
      661 agaggaaagc ataagatttc agaattgctc cttgtaccct gtttatcatg gaagcgcaaa
      721 aagcaacata gggattgagc agcttataga agtgataacg aataaatttt attcatcaac
      781 atacagaaag aagtctgaac tttgcggaaa tgtcttcaaa attgaatatt cggaagaaag
      841 acaacgtctt gcatatgtac gcctttatgg cggaatcctg catttgcggg attcggttag
      901 aatatcggaa aaggaaaaaa taaaaattac agaaatgtat acttcaataa atggtgaatt
      961 atgtaaaatt gataaggctt attccgggga aattgttatt ttgcaaaatg agtttttgaa
     1021 gctaaatagt gttcttggag atacaaagct attgccacag agagagagaa ttgaaaatcc
     1081 gctccctctg ctgcaaacaa ctgttgaacc gagcaaacct caacaaaggg aaatgttact
     1141 tgatgcactt ttagaaatct ccgacagtga cccgcttcta caatatta
//
LOCUS       DADVXM010000174         1186 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.185, whole genome shotgun sequence.
ACCESSION   DADVXM010000174 DADVXM010000000
VERSION     DADVXM010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.185"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            78..193
                     /gene="rrf"
                     /locus_tag="KB927_002666"
     rRNA            78..193
                     /gene="rrf"
                     /locus_tag="KB927_002666"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            207..279
                     /locus_tag="KB927_002667"
     tRNA            207..279
                     /locus_tag="KB927_002667"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:240..242,aa:Val,seq:tac)
     gene            283..355
                     /locus_tag="KB927_002668"
     tRNA            283..355
                     /locus_tag="KB927_002668"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:316..318,aa:Lys,seq:ttt)
     gene            363..444
                     /locus_tag="KB927_002669"
     tRNA            363..444
                     /locus_tag="KB927_002669"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:397..399,aa:Leu,seq:tag)
     gene            462..534
                     /locus_tag="KB927_002670"
     tRNA            462..534
                     /locus_tag="KB927_002670"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:495..497,aa:Thr,seq:tgt)
     gene            546..617
                     /locus_tag="KB927_002671"
     tRNA            546..617
                     /locus_tag="KB927_002671"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:578..580,aa:Gly,seq:gcc)
     gene            634..719
                     /locus_tag="KB927_002672"
     tRNA            634..719
                     /locus_tag="KB927_002672"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:668..670,aa:Leu,seq:taa)
     gene            730..803
                     /locus_tag="KB927_002673"
     tRNA            730..803
                     /locus_tag="KB927_002673"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:764..766,aa:Arg,seq:acg)
     gene            813..886
                     /locus_tag="KB927_002674"
     tRNA            813..886
                     /locus_tag="KB927_002674"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:847..849,aa:Pro,seq:tgg)
     gene            906..978
                     /locus_tag="KB927_002675"
     tRNA            906..978
                     /locus_tag="KB927_002675"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:939..941,aa:Ala,seq:tgc)
     gene            1006..1079
                     /locus_tag="KB927_002676"
     tRNA            1006..1079
                     /locus_tag="KB927_002676"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1040..1042,aa:Met,seq:cat)
     gene            1093..1166
                     /locus_tag="KB927_002677"
     tRNA            1093..1166
                     /locus_tag="KB927_002677"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1127..1129,aa:Ile,seq:cat)
BASE COUNT          275 a          275 c          330 g          306 t
ORIGIN      
        1 actcggaaaa aaacttatgt gacttcaaat ccagttttga gtgaacaaaa tttactcaat
       61 aaaagataac accacagtgt ggtggcgata gcgagaagga tacacctgta accatgccga
      121 acacagaagt taagcttctt agcgccgatt gtagtgaggg gttgcccctt gtgagagtag
      181 gacgtcgcca cgcttaagtt atccatggag gtttagctca gctgggagag catctgcctt
      241 acaagcagag ggtcagcggt tcgatcccgt taacctccat atgagccgtt agctcagttg
      301 gtagagcatc tgacttttaa tcagagggtc acaggttcga gccctgtacg gctcatattt
      361 ttgcgggtgt ggcggaattg gcagacgcac tagatttagg atctagcgcc ttacggcgtg
      421 ggggttcaag tcccttcacc cgcataattt aagttttaca tgccggctta gctcagttgg
      481 tagagcatct gatttgtaat cagagggtcg agggttcaag tcctttagcc ggcatcttta
      541 aacacgcgga aatagctcag tggtagagca ccaccttgcc aaggtggggg tcgcgggttc
      601 gaaccccgtt ttccgctttg ccaaagcaat cgcgccgggg tggcggaact ggcagacgca
      661 caggacttaa aatcctgcgg tgagtgatca ccgtaccggt tcgattccgg tcctcggcat
      721 ttcaaatatg cgcccatagc tcaactggat agagtgtttg actacggatc aaaaggttag
      781 gggttcgact cctcttgggc gcgttaatta aacgggaagt agctcagctt ggtagagcac
      841 ttggtttggg accaaggggt cgcaggttcg aatcctgtct tcccgataat tataaattta
      901 aacacggggc cttagctcag ctgggagagc gcctgctttg cacgcaggag gtcagcggtt
      961 cgatcccgct aggctccatt tcatttaaat aatgaatatc tttttcgcgg tgtagctcag
     1021 ctggctagag cgtccggttc atacccggga ggtcgggggt tcgatcccct ccgccgcgat
     1081 ttttaagagc ctggaccttt agctcagttg gttagagcag acggctcata accgtccggt
     1141 cgtaggttcg agtcctacaa ggtccattgt ggcgttgtaa gtttca
//
LOCUS       DADVXM010000175         1128 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.186, whole genome shotgun sequence.
ACCESSION   DADVXM010000175 DADVXM010000000
VERSION     DADVXM010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.186"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            10..270
                     /locus_tag="KB927_002678"
     CDS             10..270
                     /locus_tag="KB927_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841534.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(632..871)
                     /locus_tag="KB927_002679"
     CDS             complement(632..871)
                     /locus_tag="KB927_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841535.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT          397 a          162 c          207 g          362 t
ORIGIN      
        1 ggatgaaata tgaataacga aactatcatt ttaggaaaaa aatatatttg ccaacctatt
       61 ggcttgaaac aaaaagtgat tggagaagta atcagtaaat tagaaaattg tgttgtgatc
      121 tgcgtagacg aatatcatga cgtcgatcgc aatgaaatat tagaaaaatg cggaaaagta
      181 gtggcaaaat atactcacgt ttatgagttg gaaacaacag aatatctata taactatagc
      241 aacaaatatg aacatacttt agtttcataa agatttaaat aaagtgcctt caaaagcgag
      301 aagaccaagc ttttgaaggc actttattta gttggcagtg attgttcatg atttttgatt
      361 tattcaaaag gttcgcctag agaatctgtc tctgtaacga ggcctggtgg agaaactcga
      421 taaaaaccta tactgccaga actgtcctat tttcggatag acaaactagt agttttaaaa
      481 agatcatccg atccaatcat ttcaaaaaat gcaaaactga tatcaggatc atttagctca
      541 ggcttgttat cgtaaagcat ttgtaaaggt tgcatttagt taggagtaaa cgcgaaacta
      601 tcatcattat ttgctgaaga agatgaagaa gctaattcag agtttgtttg aaataaagga
      661 gacgtgctga cagtttcttt accctgtttt ttgcagaggt agaaactttt atatcggaag
      721 tttctaccgg agaatttttc tcatttgtag aaattgttga atcgatacta ttcgaaattt
      781 gcgtatctga aggtatgttc tttgatgcag aagtcccaca agcagtaagt aacaataaat
      841 ttgataaact gataaacaga attcttttca ttatgtacac actccttata gtatcgttta
      901 gcatacacct atgctcagta ttaggcaaaa tcaatgcaaa actatcaagt cttttatagt
      961 atctattagt cttagtaata catatatgga gagggtgata tcccagttca aaccagatac
     1021 attggttacc atctgtatta acgattatgc ctctaaacgc tttttttatg aaaaaattta
     1081 taagtgaaaa cgtaggtatg atattatcta gaggtaattt ttttgggt
//
LOCUS       DADVXM010000176         1066 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.187, whole genome shotgun sequence.
ACCESSION   DADVXM010000176 DADVXM010000000
VERSION     DADVXM010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.187"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(39..995)
                     /locus_tag="KB927_002680"
     CDS             complement(39..995)
                     /locus_tag="KB927_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841536.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          178 c          160 g          382 t
ORIGIN      
        1 ttttagaaaa agcagtcgga ctttctaaaa gaagttcact attcgatcct gtcgatgatt
       61 tcttcaggaa aatcgtctat ttgcttgtca attttgctgt ctttgtattt ctcttcttgg
      121 atagtcaaca aaatctttgt aagattcccc cagtctactg ctcttggcgg atcgagccaa
      181 accactactt gagatgcact ttcttcatat agattattcc tattcgtgat tataacatcc
      241 gggaactcag gctttcctgc ctctatcact tccgtgttca gattaatgta caagcttaaa
      301 tttttcttga taaattgatt ataggcagca ccataagaaa aatcgatgat gatctttact
      361 ggttcagaaa tcagttgaat gggtatgtga ttgatcaata ataataaata actgaaaaaa
      421 agaaaaaatt tatcttgaag caactctttg cgttttgacg ttagatcatt tatatactct
      481 atcaaatagc aataaaatgc tggatagttt tctctaaaaa aagaaacatc aagtggaaat
      541 tcatcagctt tattaatagt gtaatgcaaa agtttaaaat gtattttggt taactctctt
      601 cggatcaatt ggctcgtctc ttctcgcaac agattaaact gattttcaaa actttcaatg
      661 aatcgttcat tcaaccattc gattgtttca tcttcatttt ttctcaagta tttttgatcc
      721 aatttatcat gaagataaag ccaagagagt gtcttattga taaaaataac ggatttttct
      781 cctaatactc cttttaagtg gtaaaatcct atatccgaaa aaaatagcga ctgattgcta
      841 gcaatatcta aagaatcagc ttgttcagcc aacaggttga ttgctaaaaa gtggaataat
      901 ttcttttttt cataagcaga cagaggataa tactgtttta aatcttttaa cattttttct
      961 gtttttataa ttataggtag cgtatacaat tccacaaaac ttatctctgt tgagttaaaa
     1021 agattatata aaaaaagccg aatgttttta ggattccctg tcaact
//
LOCUS       DADVXM010000177         1052 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.188, whole genome shotgun sequence.
ACCESSION   DADVXM010000177 DADVXM010000000
VERSION     DADVXM010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.188"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            78..193
                     /gene="rrf"
                     /locus_tag="KB927_002681"
     rRNA            78..193
                     /gene="rrf"
                     /locus_tag="KB927_002681"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            203..276
                     /locus_tag="KB927_002682"
     tRNA            203..276
                     /locus_tag="KB927_002682"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:237..239,aa:Asn,seq:gtt)
     gene            316..405
                     /locus_tag="KB927_002683"
     tRNA            316..405
                     /locus_tag="KB927_002683"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:350..352,aa:Ser,seq:gga)
     gene            420..491
                     /locus_tag="KB927_002684"
     tRNA            420..491
                     /locus_tag="KB927_002684"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:453..455,aa:Glu,seq:ttc)
     gene            507..579
                     /locus_tag="KB927_002685"
     tRNA            507..579
                     /locus_tag="KB927_002685"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:540..542,aa:Val,seq:tac)
     gene            589..661
                     /locus_tag="KB927_002686"
     tRNA            589..661
                     /locus_tag="KB927_002686"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:622..624,aa:Asp,seq:gtc)
     gene            697..772
                     /locus_tag="KB927_002687"
     tRNA            697..772
                     /locus_tag="KB927_002687"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:730..732,aa:Phe,seq:gaa)
     gene            774..854
                     /locus_tag="KB927_002688"
     tRNA            774..854
                     /locus_tag="KB927_002688"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:808..810,aa:Tyr,seq:gta)
     gene            861..934
                     /locus_tag="KB927_002689"
     tRNA            861..934
                     /locus_tag="KB927_002689"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:893..895,aa:Trp,seq:cca)
     gene            937..1009
                     /locus_tag="KB927_002690"
     tRNA            937..1009
                     /locus_tag="KB927_002690"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:970..972,aa:His,seq:gtg)
BASE COUNT          250 a          234 c          285 g          283 t
ORIGIN      
        1 actcggaaaa aaacttatgt gacttcaaat ccagttttga gtgaacaaaa tttactcaat
       61 aaaagataac accacagtgt ggtggcgata gcgagaagga tacacctgta accatgccga
      121 acacagaagt taagcttctt agcgccgatt gtagtgaggg gttgcccctt gtgagagtag
      181 gacgtcgcca cgctgatgtt attccggcat agctcagttg gtagtagcgc atgactgtta
      241 atcatgatgt cgtaggttcg agtcctactg ccggagttct cattttgaga aagagtattg
      301 agcttctttc actctggaga gttgtccgag aggccgaagg agcatgattg gaaatcatgt
      361 agatggtgcc aaactgtctc aagggttcga atcccttact ctccgtagca aatttacctg
      421 gcccgttggt caagcggtta agacaccgcc ctttcacggc ggtaacacgg gttcgaatcc
      481 cgtacgggtc attttaattg aatgttggag gtttagctca gctgggagag catctgcctt
      541 acaagcagag ggtcagcggt tcgatcccgt taacctccat aatgaactgg ttccgtggtg
      601 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
      661 gtcgttcttg ttattcaatt aataatttta aaatatggcg cggtagctca gttggtagag
      721 caacggattg aagctccgtg tgtcggcagt tcgattctgt cccgcgccac catggaggag
      781 tagcgaagtg gctaaacgcg acggactgta aatccgttcc ttagggttca gtggttcgaa
      841 tccactctcc tccattttat aggggcatag tttaaaggta gaacagcggt ctccaaaacc
      901 gttagtgtgg gttcaattcc tgctgcccct gccatggcga atgtggcgaa gtggttaacg
      961 caccggattg tggctccggc attcgtgggt tcgattccca tcattcgccc tttttattct
     1021 tggggtatag ccaagcggta aggcaaggga ct
//
LOCUS       DADVXM010000178         1044 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.189, whole genome shotgun sequence.
ACCESSION   DADVXM010000178 DADVXM010000000
VERSION     DADVXM010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.189"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            6..398
                     /locus_tag="KB927_002691"
     CDS             6..398
                     /locus_tag="KB927_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6841537.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            399..>1044
                     /gene="aac(6')-Ie"
                     /locus_tag="KB927_002692"
     CDS             399..>1044
                     /gene="aac(6')-Ie"
                     /locus_tag="KB927_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
                     /protein_id="HBB6841538.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSV"
BASE COUNT          419 a           81 c          189 g          355 t
ORIGIN      
        1 agtttatgga agaagtttta attgatgata atatggtttt tgatattgat aatttaaaag
       61 gatttcttaa tgataccagt tcatttgggt ttatagctaa agaaaataat aaaattatag
      121 gatttgcata ttgctataca cttttaagac ctgatggaaa aacaatgttt tatttacact
      181 caataggaat gttacctaac tatcaagaca aaggttatgg ttcaaaatta ttatctttta
      241 ttaaggaata ttctaaagag attggttgtt ctgaaatgtt tttaataact gataaaggta
      301 atcctagagc ttgccatgta tatgaaaaat taggtggtaa aaatgattat aaagatgaaa
      361 tagtatatgt atatgattat gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa
      421 tatgtataag aactttaata gatgatgatt ttcctttgat gttaaaatgg ttaactgatg
      481 aaagagtatt agaattttat gatggtagag ataaaaaata tacattagaa tcattaaaaa
      541 aacattatac agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg
      601 ttcctattgg atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt
      661 atccaaaaac tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt
      721 ggagtaaagg aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa
      781 gaaatgctaa tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat
      841 accaaaaatc tggttttaga attattgaag atttgccaga acatgaatta cacgagggca
      901 aaaaagaaga ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg
      961 caatgaaata tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa
     1021 tcggtagtgg ttatgatagt gtgg
//
LOCUS       DADVXM010000179         1000 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.190, whole genome shotgun sequence.
ACCESSION   DADVXM010000179 DADVXM010000000
VERSION     DADVXM010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.190"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..434)
                     /locus_tag="KB927_002693"
     CDS             complement(<1..434)
                     /locus_tag="KB927_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841539.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHR"
     gene            complement(451..855)
                     /gene="tnpA"
                     /locus_tag="KB927_002694"
     CDS             complement(451..855)
                     /gene="tnpA"
                     /locus_tag="KB927_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBB6841540.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          304 a          172 c          163 g          361 t
ORIGIN      
        1 tgtctatgaa gcttaattct tactaatgac ttcaatttag gaactttgat gaatttacta
       61 tcaatcaaag caactgtacc attttgatta ttcgttgtat aactctgaac aggatttttc
      121 ttacttttga aacgtggaaa tccaacggat ttatcccgaa aaaaattctt gtatgcttta
      181 tctaaattaa gttgggcatt ggctaaagca aggctatcaa tttctttcaa aaacggaaat
      241 tctttcttgt atttagctgg tgtcggaaaa gtcatttttt tagaagaatc atttttaact
      301 tcttcatacg ccttttttcg gtcatcaagc attagattgt agaccttacg gacacaacca
      361 aaagatttgg caaagaagat ttcttgttcc tctgttggat agattctgaa tttgtatgct
      421 tttagttgtt ccataaagtt cacctacttt ctatttatga ttgtttcctt gattttggat
      481 atacttctta atcacatcaa ttggtgcgcc accagttgtc agaagacaaa aacttttaga
      541 ccagaacatt tctttccaaa gaaattgttt gactcttgga aagtcacgtt ttatcaatct
      601 tgagctggca cttttatagg cattgatgaa ttttgtcaat tctgttttag gttgagcttt
      661 gaacataata tgaacgtggt ctttatcatg attccactcc actaaagtaa tgtgatacga
      721 ttctgaaatt ctttcaaaag tagttttggc ataatcagat atttcatcat caatcacttg
      781 tctacgatat ttcgttacta aaacaaggtg gtaataaaga agaaatactg aatgattatt
      841 tgtatctaat tccatgttat atcaactcat ttcttgtata gactgattgt aacatggaac
      901 aaaataaaaa ggcaatacgc cttagttgtc ggtcttcgag ttaccaacgg taaccctcat
      961 accgaacggc attcatcacc cacctataga ggatgggcga
//
LOCUS       DADVXM010000180          965 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.191, whole genome shotgun sequence.
ACCESSION   DADVXM010000180 DADVXM010000000
VERSION     DADVXM010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.191"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(292..651)
                     /locus_tag="KB927_002695"
                     /pseudo
     CDS             complement(292..651)
                     /locus_tag="KB927_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          301 a          169 c          183 g          312 t
ORIGIN      
        1 ttttaatgtc tataaaatcc gttagaaaat acaatttgta gatatccaat tgatttgtaa
       61 acaaaaagga gttgtcaact aagccactcc tttttgttgt aatttttccc aataagaaag
      121 tctactactt taggaagata atagtaagat agaaatgttg cccccaaaat tattatccag
      181 ctggatataa ttaatcaaat aaaaaggatc aaaaatgtag tgacccccaa aagttagact
      241 tttttggagt ggagaaatcc actccttttt tcatgctcta aaatgatatt tttacacaac
      301 cgtaacggtt gttttacgaa attggacggg actttgacag tttaatttct gttttatccg
      361 ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct cgaaacagtt
      421 ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct ccataagtga
      481 attatctaag cagttccctt tccgagacag gctttgaaag attttgtact ccttcaattt
      541 gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg tacgacgata
      601 gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg cacgtgtttc
      661 tgaatggtgg tagcgaccga tttgaacggc tagggcggaa atacggtgca aatgcacggt
      721 ggtttcatgc aatgcttaca gggcgtattt tgtaagggta tgtaacggag atgatcccga
      781 cggtaatgga tgtgagaggc caagccgacg ctgacggtag agcaaacaaa catagttgca
      841 ctctagcgat cgttatttat ttttaacggt caaactaggg tacaactatg cttaaaacac
      901 ttcgcctcaa cttctggtag caaaagtgat tttgaaagtc aaaatatttt ttatgagtta
      961 tttat
//
LOCUS       DADVXM010000181          962 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.192, whole genome shotgun sequence.
ACCESSION   DADVXM010000181 DADVXM010000000
VERSION     DADVXM010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.192"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            269..>962
                     /locus_tag="KB927_002696"
     CDS             269..>962
                     /locus_tag="KB927_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6841541.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMK"
BASE COUNT          348 a          170 c          172 g          272 t
ORIGIN      
        1 aaaaataaat ctttcgaaaa ttccacagag attgcattaa aataaatcaa tcgacttcta
       61 ccataatgat taatttgttc atcaaactta ttgacgtgtt tcacgatttt tagtgaaaaa
      121 aactgaaata taaaaacctt attctgtcaa ggaaatagaa atatagtaag aaaaaccttt
      181 atttatcagc ttttttagac aattttttct gttacaatag tcaaggattt gtgaaaaaat
      241 caatgaaaac cgaaaggcgt gtaaaatttt gattaaatca gttgtgtttg atgttgatga
      301 tacgatgtat gatcagcagc agccatttcg aaacgcggtc aaaagagtcg ttccgcttgt
      361 ttcagatgca gatatgcatc cactatatat ccggttccgc catcatagtg atgaaaactt
      421 cccaaaagta atggcaggag attggacact agaatatatg cgagcacatc ggatcagcca
      481 atcactaaaa gatttagact accctcatat tacggaagaa gatggcctct tatttcaaaa
      541 aatttacgag gaagaacttg ataatatctg cttgcatgag gaggtcaaaa aaaccctcga
      601 tttcttgaag gaaaagaatg tcccattagg aattatcaca aatgggccga ctgaccatca
      661 gacaaaaaaa ctgaagcaac ttcaattgaa caattggatt ccttcccgca atatgctcat
      721 ttctcaagca acaggtttcc aaaaaccaga aaaagagatt tttcagctag ctgagaaaga
      781 atttcatatg cttccagaag agaccttata cgttggcgat aattacgaca atgatgttct
      841 aggtgcaaaa agtgctaact ggcaagcgct ttggttcaac catcgagaac gcaaaattga
      901 acagactcca atttgcgata tcgagatttc ttcttttgat cagctgttag agacaatgaa
      961 ga
//
LOCUS       DADVXM010000182          943 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.193, whole genome shotgun sequence.
ACCESSION   DADVXM010000182 DADVXM010000000
VERSION     DADVXM010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.193"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..>943
                     /locus_tag="KB927_002697"
     rRNA            <1..>943
                     /locus_tag="KB927_002697"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DADVXM010000183          940 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.194, whole genome shotgun sequence.
ACCESSION   DADVXM010000183 DADVXM010000000
VERSION     DADVXM010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.194"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..875)
                     /locus_tag="KB927_002698"
     CDS             complement(<1..875)
                     /locus_tag="KB927_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6841542.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTG"
BASE COUNT          323 a          111 c          159 g          347 t
ORIGIN      
        1 aaccctgtat attttttaaa agctgaagaa aaatgatgga tcgaatgaaa tcctaatata
       61 tctgcaattt ctgtataggt taattcattt tctagcacga gacgttttgc tttttccatt
      121 tttagttctt taaaatagct aataacactt tttccattca cttttctaaa atgttttttt
      181 aagctggctg gactgataaa aaaaatttgg gctaattgtt caagcaaaaa attttctgaa
      241 agatgttctt ctaaatatcg tatgattgga tcaactaatt catctgaata aagaatatgc
      301 ttttttttag gaatgacttt ctcatttgaa ggtattgtca ataaagcaag ttcctgttga
      361 taatgccttg gtaaggaaga caattgaatt ttttgcagac aataagtaac taataaggaa
      421 agcaaatgaa tgctcatctg ttggcatagt atgaaaaaag aattgatttc ctgatcatag
      481 gaaatagctg gcttactatg ttttagataa tcaattttga actgttcatt tttcagaaaa
      541 gtaatgatag atgttatttc ttgatctata gaaaaagatt gtcccgtaat atgtgctaat
      601 aattgctcat caaaataaaa ctggataatg ataaaagttt gtgtttcctt ttgagtagaa
      661 aagatttgga cttcttgctg tttatcaatg aataaaaggg aaggattatc tagttctata
      721 gatttatgtg caaattcagc atataaatta gcgctttcat ttattagtag tcgaaaatag
      781 ggagcagcag ataaatgaag atgggtatct atggaatagg ttagtgtttt tttgacaaga
      841 ttggaggatt ggttgtttgt taacaaaaga accactttcc tttctctttt tatataaaaa
      901 gctttctatt tataattaat gactattata acaaaaatga
//
LOCUS       DADVXM010000184          937 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.195, whole genome shotgun sequence.
ACCESSION   DADVXM010000184 DADVXM010000000
VERSION     DADVXM010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.195"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..>937)
                     /locus_tag="KB927_002699"
     rRNA            complement(<1..>937)
                     /locus_tag="KB927_002699"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          198 a          291 c          210 g          238 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctc
//
LOCUS       DADVXM010000185          915 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.197, whole genome shotgun sequence.
ACCESSION   DADVXM010000185 DADVXM010000000
VERSION     DADVXM010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.197"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            131..448
                     /locus_tag="KB927_002700"
     CDS             131..448
                     /locus_tag="KB927_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBB6841543.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(539..904)
                     /locus_tag="KB927_002701"
     CDS             complement(539..904)
                     /locus_tag="KB927_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841544.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
BASE COUNT          344 a          117 c          156 g          298 t
ORIGIN      
        1 taactatgca ctgtaacgat aatgctgcta aaatatcttt ttacgaaaaa catcacaagg
       61 aaaaacttaa ctatggtatt atctaaacat aattttttcg gtatttaata tttaattagg
      121 aggtaatatt ttgctttttt atagtaattt tatcttaata gtagcgatat tattacttct
      181 gaatatatgg atttttgata ggagtagaaa tgcaagtata ggttttagaa ctaaacgaag
      241 tctgtcttct aaaaaaaatt gggtatactc acaaactatt ttttatggag gaattgtttt
      301 aattagttta ctttcttcaa cactttattc tttgaatatt atagatgttt ccacctcaaa
      361 ttcaatatct attattggaa tcattattgc tgcaattatt acacaactgt ttttagtgtt
      421 tggagagaag aaaagaagta aaaaatagaa aaactagtga tagttttggt gatataagaa
      481 aaacatatat gtataaaaag aagaaagtag cttctctttg tacatatatg gtttgttttt
      541 atggatgccg agctttttta taagataagg ctaccgccca taacgaccca aggatttgtg
      601 gaactaagta aatacctgca agaagcaaga tcagctgggt cggttttaaa ggatgataga
      661 agtaacgcca ttcagtaaaa ttggcgcaaa ataaatagga agtgacagta gatataatat
      721 tggcaatgaa taaagatata atacgcctgt tcctttgaaa ataatatcca gcaaaaagag
      781 ataaaaatat caatgtgatg aacccgctta cggaatgata acgaaaatca agcagtaagg
      841 cgaaatgcac ataaggaaca aaagataaaa gcaacggaag gtttttccag caagttttta
      901 tcatctttca tcacc
//
LOCUS       DADVXM010000186          891 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.198, whole genome shotgun sequence.
ACCESSION   DADVXM010000186 DADVXM010000000
VERSION     DADVXM010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..891
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.198"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(85..>891)
                     /locus_tag="KB927_002702"
     CDS             complement(85..>891)
                     /locus_tag="KB927_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBB6841545.1"
                     /translation="TYYYQAKPIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGL
                     QLSRRRIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTTNVLDRTFTQEQPLEAIVTDL
                     TYVRVRKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTDVKLFHTDR
                     GKEFDSQTIHEILNGFGITRSLSRKGCPYDNAVAESTHKSVKVEFVHQYQFETLAQLR
                     LELFDYVHWWNYLCLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          234 a          210 c          172 g          275 t
ORIGIN      
        1 atgctgcggt gttatggctc cgattgccct tgacaatgag catcctcgga tctgattttc
       61 tccggcagaa gcacaatcat tcaattacgc tgcctctcca gaggtatcag atccgcgctc
      121 attatcaagg attcgcttcg ccaatctctg ttgtcgaatt tggatcggtg tttcatacgc
      181 caacgtgcca tgtaagcata gatagttcca ccaatgcaca taatcaaaca attctagacg
      241 tagctgtgcc agtgtctcaa attggtattg atgcacgaat tctactttga cagatttatg
      301 ggttgattcc gcaacggcat tatcatacgg acaacccttc ctactcaatg aacgagtaat
      361 tccaaaacca ttcagaatct catgaatggt ttggctatca aattcctttc cacggtctgt
      421 atgaaaaagc ttgacgtctg ttaaagaata cggtatccgt ccaaaggctt cttttaccaa
      481 tgaggcatct ttcttctcac cacaggaata accaataatt tctcgattaa acaaatcaag
      541 tattaagcag atataatgcc actttttcct cacgcgaaca taagtaagat ccgtaacgat
      601 ggcttccaat ggctgttctt gtgtaaaggt ccgatctaat acattcgttg ttttcgcttc
      661 attacaagct gttcgttgcc ctttaaaatg agcgatcgta taggtagatg tcaatccgcg
      721 gcgtttcatg attcgaccga ttcggcgccg actgagttga agcccacgct ttgctaaaca
      781 cttcttcaat tttcgggtac cgtaagcctt tcggtttcga ataaactctt cctgaacgat
      841 ctcttctaag tcggactcat tttcgatcgg tttcgcttga taatagtagg t
//
LOCUS       DADVXM010000187          870 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.199, whole genome shotgun sequence.
ACCESSION   DADVXM010000187 DADVXM010000000
VERSION     DADVXM010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.199"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            126..326
                     /locus_tag="KB927_002703"
     CDS             126..326
                     /locus_tag="KB927_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841546.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            338..664
                     /locus_tag="KB927_002704"
     CDS             338..664
                     /locus_tag="KB927_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841547.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
BASE COUNT          369 a           93 c          160 g          248 t
ORIGIN      
        1 caaactatta tagcatgaaa accacaaatt gagtaatatt ttaattgata ttactcgttt
       61 tgtggtttaa aatgtgctta ttaagataaa aaccacaaag tgaataattt gaaaggaggc
      121 gctgaatgat aactcttaat gatcaattca ttagaagctt aagaagacat agagccgatc
      181 ttatacttac taaaaacgat gcagcaaaat tgataggtat aaatcggaaa acatatgtca
      241 aaatcgaaaa tgggagcaaa gaaagtatta gagcatctac ttatcaaaag ttggtaaatt
      301 ggttacttaa tgatttgaaa atctaaataa atacaacttg gcgagttggc tgattgaaga
      361 aatagaaaat gagaggagaa aaataatgga tgcaggaatt acagtaatgt tagataaaca
      421 acaaacgaat caattgaaaa attatgtttt tgaaatgaca aaagaggcta ttgatcaagc
      481 aagaattgat accggattag aaagaccatt tctaaaagga aaagagatgg ctaaatattt
      541 gaatgtatca tatacaactt ttttgaaatt taaaagaatg ggattgccag ttattttatt
      601 agaaaaaatg gagttgtttt caaaagaaga atgcaaaaaa tggatattga gtcatcaaat
      661 ttaaaaaaca cctcgttttt taaatttgat gaagtagaaa aaattaaaaa gagtgttccc
      721 gtcagtttgc agatcggggg aacactcaat aataaagttc tgagaaaact ttatttgaat
      781 ctattatagc aaataaaatc agaagcaggt gtgacaatga atgaaaaaga agttgaaagc
      841 ttagttgaaa agcaaggcta ttctaattct
//
LOCUS       DADVXM010000188          862 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.200, whole genome shotgun sequence.
ACCESSION   DADVXM010000188 DADVXM010000000
VERSION     DADVXM010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.200"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            126..827
                     /locus_tag="KB927_002705"
     CDS             126..827
                     /locus_tag="KB927_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6841548.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT          312 a          151 c          144 g          255 t
ORIGIN      
        1 acataataac aaattatatt tgtaaagtat taaaacttgt ttctaatgtt ggtatgttaa
       61 aactttacaa attctttaaa aaaagtgaca ataaatatag tgaacaataa ggagaggact
      121 ttttaatgcg tgttaataaa atcgattttc acttttcaaa actcagatat caacctgatt
      181 ttgaacattt ctcggatgaa gagttccaac agatcaagga acatactgtt cttcgttctt
      241 ataaaaaagg acagatcctt ttcgacgatg gtgatcccag acaacggttg tatatcttga
      301 ccaaaggact cgttcgttta gaacgttatg atgaaagtgc aacttattac tactatgact
      361 atgtgaatac aaataacctt tttcctatgt caggaatgtt tggagaagag acctacactt
      421 atacagctca agcgatgact gatattgaaa cattctacct tcctgtttcc tactatgaaa
      481 aattagcacg aaaaaatccc gaacagttga tctatatgat acaaaaaatt tctaaagtag
      541 ttgaaataca tgaattgcgt atccaaatcg gattgacctc tagcgccttt gaccgggtaa
      601 aacaaaattt attcattttg aaagaagaat tgggcgtacc aacaaaagat ggtcatatca
      661 ccattcctta tccgatcacc ttaaaagaat tagcagtgaa tagcggcacg acacgtgaaa
      721 ctgctggaca agtaatcaaa caactacgtg attccggact gttagattat gacaaaaagc
      781 gttttacttt ctgtaagaca gctactactc cagctatgag agaataacgc gaacaaaaat
      841 aagcagtgac cctgatattt at
//
LOCUS       DADVXM010000189          852 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.201, whole genome shotgun sequence.
ACCESSION   DADVXM010000189 DADVXM010000000
VERSION     DADVXM010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.201"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            124..>852
                     /locus_tag="KB927_002706"
     CDS             124..>852
                     /locus_tag="KB927_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HBB6841549.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIK
                     IIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLK
                     IHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHKIHEKLALKG
                     ITISVPPRKNMDKSEKLDHSLLGKQ"
BASE COUNT          309 a          156 c          141 g          246 t
ORIGIN      
        1 ataaatatct atacccgtgg tgctagttaa ttttttctta gaggaaaatg tctaaacatg
       61 ttggtaaatc aacaaaaaaa cgcatatagt agtctcaaaa ctcccaagaa atgaggacta
      121 catatgcgtt catcaaaata tactgaacat tatacagata cttttataac attcaaggaa
      181 attatgagaa ctgtttctaa catataccac aattgtgtac cagataagat taaaaaccga
      241 agaaatactg atcaactgaa gcaacgcgat acagtgatta ttgcttgtgt tatatggggc
      301 ataattaatg gctatactag ccaaagagcc acgtatagag cggtttgttc cgtcttattt
      361 cctaatggtg actttcctag taggagtcga ttcactcgct taagttcaaa cttagcttac
      421 actatcaaga ttattcgata ctttttcatc aagaagctca ccaaaggtga actagtcgga
      481 attatagata gttttcctag tccattatgt aaaccagtta gaaatagaca agcaaaacta
      541 ttgaatcaaa tagccaaagt tggctataac tcaacaaaaa aatcttattt ttatggtctt
      601 aaaattcata tgatcgttac taagactggc tttccgatta cttactcaat cacgaatcca
      661 ggtgtccatg acgtgaaagt gttagagact ttatcggaag aagcgaatct tcccaatatc
      721 ctaggggaca aaggatatat tagccataaa atccatgaaa agcttgccct taagggcatt
      781 actatatccg ttccgccacg taaaaacatg gataaatcag aaaaactaga ccacagctta
      841 cttggaaaac aa
//
LOCUS       DADVXM010000190          845 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.202, whole genome shotgun sequence.
ACCESSION   DADVXM010000190 DADVXM010000000
VERSION     DADVXM010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..845
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.202"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(438..>845)
                     /locus_tag="KB927_002707"
     CDS             complement(438..>845)
                     /locus_tag="KB927_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBB6841550.1"
                     /translation="IIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDIS
                     ILSKIPREYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQ
                     FYQALKYARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          279 a          129 c          152 g          285 t
ORIGIN      
        1 atttctaaaa tacgcaaaaa aataaaattg aagatgttat taaatcgcga ttatttacgg
       61 agatttatat aaataaaaac cccctgacga agtcgaaggg ggtttttatt ttggtttgag
      121 gtttgcatac ctaccgaaaa ggtagggcag caaatcgtca aacaggtatc agctaattgc
      181 accataaggg tgcgctgata ctcggctcaa aagagccgaa agagccgtct gcaagacccc
      241 tcggcgagcc cacactttgc ttgcaaagta tagtgggtta tactttacat ggaagtaatt
      301 gccggaaata gtgaaaatgc ctcacatttg tgccacctaa aaaggagcga tttacatatg
      361 agttatgcag tttacgggcc aagattgttt aagcaaaata agataagtta agggatgcag
      421 tttatgcacc ccttaactta tctattaaat aatttatagc tattgaaaag agacaagaat
      481 tgttcaaagc taatattgtt taaatcgtca attcttgcat attttaaggc ttgataaaat
      541 tggtttttgg aaaatagttt tatgtattct ttgttaaccc atttcataac aaaattttca
      601 tattgttttc tatctttgag tgatattttt gaagggtgtc tttttaatac aattaacgag
      661 ctattaactc taggttttgg atgaaagtat tctctaggga ttttacttaa tatggatata
      721 tcaacttctg tcattaaaaa tagtgctagt gaacgatttg tatttagcaa ccttttagca
      781 aatccatatt ccactattaa ataactttct gtagctgtgc tttcaaaaac aatttttcga
      841 attat
//
LOCUS       DADVXM010000191          821 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.203, whole genome shotgun sequence.
ACCESSION   DADVXM010000191 DADVXM010000000
VERSION     DADVXM010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..821
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.203"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..90
                     /locus_tag="KB927_002708"
     CDS             <1..90
                     /locus_tag="KB927_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBB6841551.1"
                     /translation="RRNKFYQSLRTASSTIKGMETIRGIYKKN"
BASE COUNT          305 a          120 c          124 g          272 t
ORIGIN      
        1 cgacgaaata aattttatca aagtctccgt acagcctctt ccacgattaa gggcatggag
       61 accattcgag gaatatataa aaagaactga agaaatggaa cgctcttcgg cttttcggtg
      121 tctactgaaa tcaaggtatt aatgggaata acagcctaag atatttggag ttcagagagg
      181 gcgcgtttga ttttcaaact tcgcaacaga acccattagc aatatataaa agaaggtatc
      241 aagagtcaca gtgaatttat tccgaaaagt gaaaagagca aatataaaat ttaataaaaa
      301 taagaactaa ataggaaaac gtagacgtaa ttttctacgt tttccttttc atatatatta
      361 aatattacgg aaaattatat aaactaattt agtgttttgt ttgtaattcc taattttgct
      421 ccacttttag ataattttta ggtctattta actcattaga cattctatgc tcatttttct
      481 ccaaatttgt ttcaactctt tcgtacttaa ttttgcgtat ttgaaaattc ttcttttaga
      541 gtacttttat tacgatacta gtatgatata tatctacagc aaacagttaa aatcttccta
      601 aaataagcga atagcattcc taaaacctat aaaattttta gatgaagcga caagtggaca
      661 attaataaac tacttgaaca tgaaattatg gatcaccttt caaatttaga aaatggaatt
      721 cttatactta ttgcgcaaca tttattgatt gcaaaattat gtgacaaaaa gaactagtag
      781 aagaaggaat aatggcttga taataaagta ctacctatta a
//
LOCUS       DADVXM010000192          811 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.204, whole genome shotgun sequence.
ACCESSION   DADVXM010000192 DADVXM010000000
VERSION     DADVXM010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.204"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..672
                     /locus_tag="KB927_002709"
     CDS             <1..672
                     /locus_tag="KB927_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6841552.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          298 a          126 c          152 g          235 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaag cgttaagaac cgtcaggttt a
//
LOCUS       DADVXM010000193          809 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.206, whole genome shotgun sequence.
ACCESSION   DADVXM010000193 DADVXM010000000
VERSION     DADVXM010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.206"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            167..361
                     /locus_tag="KB927_002710"
     CDS             167..361
                     /locus_tag="KB927_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841553.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            630..>809
                     /locus_tag="KB927_002711"
     CDS             630..>809
                     /locus_tag="KB927_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841554.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKI"
BASE COUNT          335 a          102 c          132 g          240 t
ORIGIN      
        1 aagaacaata gccttttatt atatatatta ttcaaattag ttatatcgag tgaaaaaaac
       61 tttcaaattg attcttttta tttatcataa agatatagat acataatcat tttcacttac
      121 atatatttga atattaacta aaaacagcaa gaaagaagag gatcaaatgt attatgtaga
      181 agtaaaaaca aaaggcgtca aaaacaaaca atatgtgaaa ggtatcagta acgaatatcc
      241 tttacttggt tcatggaaag aagctgctcc tttttccaaa ccatgtgcca taaaaataaa
      301 gaacgagcta gaaaaagaac tgacttgtgg taaagctgtt gtagatatca tcgaaaagta
      361 aatccaatgt atagaaagga agatcacaca tgaaaagcga cgtacaaatt gctaagatta
      421 tagaattaga agaagaagac gcagtgttga caattgaaaa aaaataaatg tttgtatacc
      481 atatgattat ttcaatatgt atcctggaat tggagatctc gtagagctat atcaagatga
      541 atcaaatata cttgtcattc atcatgaaat atagagactt ataaaattgt ttatttttat
      601 aatgtatcag tatagaaagg aaataaaaca tggattatac tgttgaattt gacagtgaac
      661 tacttaagca atttccacaa gaagaacatt tcatgtataa agaagcaatt tcccacaaag
      721 tgacagagta tttggagcat aatttttttc gtataaagcc agtgcgtact cgttcggcaa
      781 aaggaatata cgagatgaaa gtcaaaatt
//
LOCUS       DADVXM010000194          809 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.207, whole genome shotgun sequence.
ACCESSION   DADVXM010000194 DADVXM010000000
VERSION     DADVXM010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.207"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            202..>809
                     /locus_tag="KB927_002712"
     CDS             202..>809
                     /locus_tag="KB927_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841555.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVT"
BASE COUNT          276 a          120 c          162 g          251 t
ORIGIN      
        1 caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa atgaaaaaag
       61 tagtccattt tgaagtacat tttgtcattt tgtactccaa aactgaacta cttacttgca
      121 tatatacgcc tttatagtgg agtactacat ttacgagatt cggttagagt atcagaaaaa
      181 gaaaaaataa aagttacaga aatgtatact tcaataaatg gtgaattatg taagattgat
      241 agagcttatt ctggagaaat tgttattttg caaaatgagt ttttgaagtt aaatagtgtt
      301 cttggagata caaaactatt gccacagaga aaaaagattg aaaatccgca ccctctacta
      361 caaacaactg ttgaaccgag taaacctgaa cagagagaaa tgttgcttga tgcccttttg
      421 gaaatctcag atagtgatcc gcttctacga tattacgtgg attctacgac acatgaaatt
      481 atactttctt tcttagggaa agtacaaatg gaagtgatta gtgcactgtt gcaagaaaag
      541 tatcatgtgg agatagaact aaaagagcct acagtcattt atatggagag accgttaaaa
      601 aatgcagaat ataccattca catcgaagtg ccgccaaatc ctttctgggc ttccattggt
      661 ttatctgtat caccgcttcc gttgggaagt ggaatgcagt atgagagctc ggtttctctt
      721 ggatacttaa atcaatcatt tcaaaatgca gttatggaag ggatacgcta tggttgcgaa
      781 caaggattat atggttggaa tgtgacgga
//
LOCUS       DADVXM010000195          789 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.208, whole genome shotgun sequence.
ACCESSION   DADVXM010000195 DADVXM010000000
VERSION     DADVXM010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.208"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..385
                     /locus_tag="KB927_002713"
     CDS             <1..385
                     /locus_tag="KB927_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841556.1"
                     /translation="ISEDVESQQFGTNVINKVINPALSINAPLIPTALSFSVTAVVSE
                     IEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLVEEAGEHYA
                     VVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            399..>789
                     /locus_tag="KB927_002714"
     CDS             399..>789
                     /locus_tag="KB927_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841557.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVAT"
BASE COUNT          287 a          107 c          143 g          252 t
ORIGIN      
        1 aatttcagaa gatgtagaaa gtcagcaatt tggcactaat gttattaata aagtaattaa
       61 tccagctctt tctattaatg cgcctttaat tcctactgct ttatcatttt ctgtaacagc
      121 tgtggtgtct gagatagagg atacagaaaa gataaaaata gtagaaattg aagttttaaa
      181 caagaatgaa aaacaaattt tttctacggg tgaagtatcg gtaagcttgc ctcctcaagt
      241 taacgatata aactttaata taaacgccag aaatgtcttg gttgaagaag caggagagca
      301 ttatgctgtt gttaaattta atggaactga gattggaagg caaatctttg atatcaaggt
      361 caacaaacca gtggaaaaaa attaaggaga cgatacggat gcttgatata gtaccatcaa
      421 atacacatcg gagtggtagc ttaataaatt ttgctgcgat ttttgcttgc gcatcggtaa
      481 ttctagcatc tccagttgtt gtggatgcaa gttctactcc gaaaactaaa aatgataatc
      541 aacttgtaat tactacaaaa aatgagatta acacaatttc aagtaatgat ggcaaaattt
      601 ttgatgtgat aaatacggtt ttaaaaagaa aagctgaaat caatataaaa tatgatgaag
      661 atttaaactt gtatttcttt gttatcaaaa caacatctga attgttttcc tcagattacg
      721 atgttttgga tactctcgat aatgtattat ctgactataa atatatgggg aaatctgtag
      781 tagcaactt
//
LOCUS       DADVXM010000196          765 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.209, whole genome shotgun sequence.
ACCESSION   DADVXM010000196 DADVXM010000000
VERSION     DADVXM010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.209"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            660..>765
                     /locus_tag="KB927_002715"
     rRNA            660..>765
                     /locus_tag="KB927_002715"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          315 a          124 c          134 g          192 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactctc gatgaagtag acctttgaaa actgaacaaa
      541 gtaagacaaa ccaaatgtgt agggcgtctt gattcaattc aagacaacaa acatttttaa
      601 caagcaagca atatgctagc aaacaaattg agcttaacaa tcgcaagatt gttcgaactt
      661 tttatgagag tttgatcctg gctcaggacg aacgctggcg gcgtgcctaa tacatgcaag
      721 tcgaacgctt ctttttccac cggagcttgc tccaccggaa aaaga
//
LOCUS       DADVXM010000197          714 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.210, whole genome shotgun sequence.
ACCESSION   DADVXM010000197 DADVXM010000000
VERSION     DADVXM010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.210"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..688
                     /locus_tag="KB927_002716"
     CDS             <1..688
                     /locus_tag="KB927_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6841558.1"
                     /translation="LERYFSRFSLATREAVQLIVIDMYAPYVSLVKKLFPNAQLIIDR
                     FHIVQHIGRTFLNHRVKETTVRLKGNSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVW
                     RASFKDYLTESEIADRLLAACPNLRQGYQLYQDILYAVKKRDQSLFEDCLTRDISGLP
                     ETYTTTLRTFKKFLPQIQNALHYSYSNGPLECLNNHIKVLKRNAYGFRNFYNFKLRIM
                     IRHGKTFLTK"
BASE COUNT          233 a          142 c          133 g          206 t
ORIGIN      
        1 tttagaacgc tatttttctc ggttttcatt agcgactcgt gaagccgttc aattgattgt
       61 tattgatatg tatgcgcctt atgtttcgtt ggtgaaaaag cttttcccga atgctcagtt
      121 gatcatcgat cgtttccaca tcgtccaaca tattggcaga actttcttga atcatcgagt
      181 gaaagaaacc acggtacgac ttaaaggaaa ttcccactct caacgagggt tagggaaaaa
      241 attgaagcgc tattggaaac tcctacaaaa agaagaagca aagttaaact atgaaaaacg
      301 ggtttggcgt gccagtttta aagattattt gactgaaagt gagattgccg atcgactgtt
      361 agctgcttgt cccaacttac gccaaggcta tcagttatac caagacattc tttatgcggt
      421 aaagaaaaga gatcagtcac tatttgagga ttgtttaact agagacatta gcggtctgcc
      481 agaaacctat acaaccactt tacgaacgtt taaaaagttt ctgccacaga tccaaaatgc
      541 gcttcactac agctattcaa acggaccatt ggaatgctta aacaaccaca tcaaagtatt
      601 aaaacgcaat gcgtacggct ttcgcaactt ttacaatttc aaactacgaa ttatgattcg
      661 tcatggcaaa acatttttaa ccaaataaac agaacagaaa gaggttttct tctt
//
LOCUS       DADVXM010000198          696 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.211, whole genome shotgun sequence.
ACCESSION   DADVXM010000198 DADVXM010000000
VERSION     DADVXM010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.211"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(53..628)
                     /locus_tag="KB927_002717"
     CDS             complement(53..628)
                     /locus_tag="KB927_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6841559.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          125 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DADVXM010000199          695 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.212, whole genome shotgun sequence.
ACCESSION   DADVXM010000199 DADVXM010000000
VERSION     DADVXM010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.212"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            121..>695
                     /locus_tag="KB927_002718"
     CDS             121..>695
                     /locus_tag="KB927_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBB6841560.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHA"
BASE COUNT          213 a          135 c          130 g          217 t
ORIGIN      
        1 ctctatactt tttgatgttg gtgaacttca ccaacatctt ttttgtataa aaaaatatag
       61 aaaagacacc ctgaaatcct ttagaattaa tttggctacc aattcatagg aggattcaag
      121 atgtctcata ctcagcttat caaagatacc ctaaatattc tagacctaaa tatctatttc
      181 gaggaaaatt gtttaactaa agaaaaatac aaagggcaaa tttgcttgat ttacaaagga
      241 actcttctgt acaagccaga agagtgttcc cattgtcttt gtgtcgtccc ctctaggatc
      301 attcgttggg ggacgacaac cgttcggttg ttactgaatg atgtgtctga gtatcgcact
      361 tatctggagc tgaagaaaca acgatttaaa tgtaagtctt gccaaagaac attcgtagcg
      421 gatacctctg ttgctgaaaa acactgtttc attagtcaaa aagttcgttg gtctgtcatt
      481 gctcgcttaa aagagaatac ttccatgacg gaaatcgctc gtcagaaaaa tatttccact
      541 tcttcggtct atcgtgtcat gaagcgattc taccgcccat tgaatccttt caaacagact
      601 ttgccaaagg tcttatgctt tgatgaattc aaatcggttc gaagtgttgc cagtgcaatg
      661 agttttatca tgatggacgg acaaagccat gcatt
//
LOCUS       DADVXM010000200          694 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.213, whole genome shotgun sequence.
ACCESSION   DADVXM010000200 DADVXM010000000
VERSION     DADVXM010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.213"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(82..636)
                     /locus_tag="KB927_002719"
     CDS             complement(82..636)
                     /locus_tag="KB927_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6841561.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          208 a          143 c           69 g          274 t
ORIGIN      
        1 acttccgaaa attcagttat cttcattaat ctcaccttct aagttttcat tatacacaaa
       61 aaatatatcc taatatctca attagcctcc caatttaaaa ccacgtaacg atgcccctat
      121 ttcatcttca gttataccaa tgtacctttt tgtaattgct tgcgagctat gattaaaaat
      181 aaacattaag gtagcaatgt ctctagtttt cttgtagtag tgatacccaa aagtttttct
      241 taatgtatgt gttcctatat catctcttcc taatttttct gctatatctg catatatctg
      301 atagacacga tcccttgtta tatgtcgacc ttgttgccga cttggaaata accaatcatt
      361 ttcttcttta ccttcagtat ataataaaat ctcttctctc aaattatcta taaaaatcgg
      421 ttttcgctta cctgttttat gttcaacaat aataggctta cttttacctc gtatgtctcc
      481 aacttttaat cctataatat ctgacatacg taacccatta ttgattccaa acaaaaataa
      541 aaaactatct ctttctggat tacttgttct tcttagccaa aactgaaaat cttgtatctc
      601 ttcatttgtc cttaacggtt gtacattata gctcactatt gtttcccttc ttaaaaatat
      661 tctgagttca tgattatata tatattttac cata
//
LOCUS       DADVXM010000201          636 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.214, whole genome shotgun sequence.
ACCESSION   DADVXM010000201 DADVXM010000000
VERSION     DADVXM010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.214"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..448)
                     /locus_tag="KB927_002720"
     CDS             complement(<1..448)
                     /locus_tag="KB927_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841562.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT          186 a          116 c           87 g          247 t
ORIGIN      
        1 tcaactttct cttttcaaaa aaaatttgat atttttttag atttcttttt agtctttgta
       61 atactttata agccacagaa taactcacgt gatgctgttt agcaaaattt tctactgaga
      121 tatatttttc ctgaaagaaa gccaatacca ttttcataga taaagaatcc gttatataac
      181 gagataacag agctttgcta gaacattttc cattaatttc cagacatata tccaattcac
      241 tgacggttac tcgcaaattt ttctctagat cgaacttttg taaatcatgt ttcagcttat
      301 cgatcgtttt tttcaagaga aatgtcgata gcgacaactc ttcttgaaca ttcgatattg
      361 actctgataa atttgagctt gcttctaaat atttaagtaa tgaataactt ctgtgatctt
      421 ctttgcttaa aaaaaactca taattcatta gtcatcagct ctttctacgt atattacttt
      481 ccatgcattc accaactagc tggggataaa actgatttcc tggatccgag tcactgttgt
      541 cagcgattct tgtttgtata atatacatcg tcctgtcttt tttttaacat tttggagagc
      601 gttttatttg gcctttctcg cgatcaaacc tgttat
//
LOCUS       DADVXM010000202          580 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.215, whole genome shotgun sequence.
ACCESSION   DADVXM010000202 DADVXM010000000
VERSION     DADVXM010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..580
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.215"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..>580
                     /locus_tag="KB927_002721"
     CDS             <1..>580
                     /locus_tag="KB927_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841563.1"
                     /translation="ELKNLNIGNNIKNIRKSKNMTQTDFAELMGLSRSYIGDLENNRR
                     NPSIKTLEAIARALDVPIVALINDSSTDNIVEPYESLTAENILLKQENEELKYEVESL
                     RKRLYEIQQVVNQGAEKMIPNLKDVSKRIKYIRKKLGMTMEQFGSHLSNSPKSTIATW
                     ESGRNIPSQKKLQLIAIVGETTTDWIKWGTLE"
BASE COUNT          244 a           83 c          108 g          145 t
ORIGIN      
        1 ttgaactcaa aaaccttaat attggaaaca acatcaaaaa tattagaaaa agtaaaaata
       61 tgacacaaac tgattttgct gagttaatgg gtctatcacg atcatatata ggggatttag
      121 aaaacaacag gaggaatccc agtataaaaa cactggaagc tattgcaaga gcattggacg
      181 ttccgatagt agcattaatc aacgattctt ctactgataa tatagtagag ccgtatgaaa
      241 gtttgacagc cgaaaatatc cttcttaaac aagaaaatga ggaattaaaa tatgaggtag
      301 aaagcttacg aaaaagattg tatgaaatcc aacaagtagt aaatcaagga gctgaaaaaa
      361 tgattcccaa tctaaaagac gtaagtaaaa gaatcaaata tatcagaaaa aaattaggta
      421 tgactatgga gcaatttggt tctcatttaa gcaactcacc taaaagtaca attgctactt
      481 gggaaagtgg tagaaatata ccttctcaga aaaagttaca gctgattgct atagtaggag
      541 aaaccaccac tgactggatt aaatggggaa ctttagaaga
//
LOCUS       DADVXM010000203          544 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.217, whole genome shotgun sequence.
ACCESSION   DADVXM010000203 DADVXM010000000
VERSION     DADVXM010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.217"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(71..157)
                     /locus_tag="KB927_002722"
                     /pseudo
     CDS             complement(71..157)
                     /locus_tag="KB927_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          209 a           87 c           53 g          195 t
ORIGIN      
        1 atgaaatacc tctttgttac tcataattat accataatta gtcacgaatg caaccaatag
       61 aaaaaaatac ttagaacggt agatcatcgc taataacaat gcattgtcca ccaaatggat
      121 tttgtgaagc attaaataca ttgttattaa ttgtcgctgc ttttaactag gcctctcccc
      181 ttctattata aaagaagata tatattattt cttaattacc tactacctta aaccaaaatt
      241 taagtactac ctaatttaag tagtacttaa ataatctaaa aaatagttat cccaattgtt
      301 atgcttttat aatacgatta tttgtaacaa aatgaatatt atataattaa acactaccat
      361 atttaggtag tgtttaatta ttagcaaaac aaaaaatatt tattctattc tcttaacttc
      421 aactaagtta tgctgcacac ctttatataa atcatatgca actcattagc tagacaaact
      481 acaagcatgt agttttatct gttaattatg tactacctaa ataaattagt ttataattaa
      541 caag
//
LOCUS       DADVXM010000204          482 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.220, whole genome shotgun sequence.
ACCESSION   DADVXM010000204 DADVXM010000000
VERSION     DADVXM010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.220"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            35..>482
                     /locus_tag="KB927_002723"
     CDS             35..>482
                     /locus_tag="KB927_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6841564.1"
                     /translation="MHKISVIVPAYNVEDYLENCLESISNQTHSNIEIIVVNDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNL"
BASE COUNT          189 a           59 c          102 g          132 t
ORIGIN      
        1 aaataaaaaa gatgattttt aggaagtgaa gagagtgcat aaaattagtg ttatagtacc
       61 cgcatataac gtagaagact atttagaaaa ctgcttagaa tctatttcca accagacaca
      121 ttcaaatatt gaaataatag tagtcaatga tggttccccg gatcgaagtg gggaaattgc
      181 agaagaatat aaaaagaaag atatgcgatt aaaagtgata catcaagtga atggtggttt
      241 aagtgcggct aggaattctg gtcttgattc tgcaacagga gattttgtgt gctttattga
      301 cagcgatgat tggatagaac cagactatct tgagttacta tattttggca cgcaaactta
      361 tggagcagat atctcggtgc taaaaataaa aaagatttca agtttagaac aactaaaaga
      421 acatacaatt gctgagagaa aatgggaaat atttgataga gaacaagcaa tgaaaaactt
      481 at
//
LOCUS       DADVXM010000205          461 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.221, whole genome shotgun sequence.
ACCESSION   DADVXM010000205 DADVXM010000000
VERSION     DADVXM010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.221"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
BASE COUNT          160 a           78 c           68 g          155 t
ORIGIN      
        1 tatcagtcgc aatattattc ttttcataaa tattgtaaat agaagtatta aaaatatata
       61 caaaaagtat tatttcgaga aagataaata ttttcaaaaa ccttttcata atcctcaccc
      121 tttcttacac tgataaatca tgcgtctaat attcaaatta tactcgatat gctttagcta
      181 atcagccaac tctgtttgtc tactatcatt atatcaatag acaatatctg ctcccgtctt
      241 tatgatcgtg ccaaagcaat caaaagaaaa ttgcgaatca cttagatcga aagtttactc
      301 aaacaaaagc attgtcagcg gttgtcacgg atttaactta tgttcgggtc gggacaaatt
      361 gggcttatat ttgtttgatg attgatttat tcaatcgtga aattattggc cattcttgcg
      421 gaaataaaaa agatgcgcag cttgtaaaaa gggccattca a
//
LOCUS       DADVXM010000206          460 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.222, whole genome shotgun sequence.
ACCESSION   DADVXM010000206 DADVXM010000000
VERSION     DADVXM010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.222"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(20..91)
                     /locus_tag="KB927_002724"
     tRNA            complement(20..91)
                     /locus_tag="KB927_002724"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="KB927_002725"
     tRNA            complement(113..200)
                     /locus_tag="KB927_002725"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="KB927_002726"
     tRNA            complement(225..298)
                     /locus_tag="KB927_002726"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="KB927_002727"
     tRNA            complement(312..382)
                     /locus_tag="KB927_002727"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="KB927_002728"
     tRNA            complement(384..459)
                     /locus_tag="KB927_002728"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DADVXM010000207          444 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.225, whole genome shotgun sequence.
ACCESSION   DADVXM010000207 DADVXM010000000
VERSION     DADVXM010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.225"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..379
                     /locus_tag="KB927_002729"
     CDS             <1..379
                     /locus_tag="KB927_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6841565.1"
                     /translation="HRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLRYYFVKRGTE
                     GFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNGVTEGLNNKIKLIKRIA
                     FGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT          141 a           93 c           80 g          130 t
ORIGIN      
        1 tcatcgactg tttaaacgac caattagtca aacagaaatc gttgatgagc tgttaagcta
       61 caacgaagaa ttgcgaactg cgtatcattt ttgtcaatta ttacgctatt atttcgttaa
      121 acgaggtacg gaaggctttc aagaaaccct taaaacaatt tcatctacgt tacctcagtc
      181 gtttaaaaag aaattcacga tcttccatcg ctaccaatcg ggtatttcaa atgcctttaa
      241 ggtgtcccac tcaaacggcg tcactgaggg gctgaataac aagatcaagc tgattaaacg
      301 aattgcgttt ggttatcgca acttttataa ctttcgggca cggatctatt tacaacaagg
      361 tctgatcttt gaaaactaaa aaaatatgcg gcgcacagaa cgcgccgcat atcggactaa
      421 gttttattca aatttgtctt cacc
//
LOCUS       DADVXM010000208          427 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.226, whole genome shotgun sequence.
ACCESSION   DADVXM010000208 DADVXM010000000
VERSION     DADVXM010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.226"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..>427
                     /locus_tag="KB927_002730"
     CDS             <1..>427
                     /locus_tag="KB927_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6841566.1"
                     /translation="LFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPK
                     SILRGSFNPRIFDSFEVHEDILIFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTN
                     KEDYLRSINILQRFEKEVKIDPDFSPKLKKLVKFLLINKN"
BASE COUNT          168 a           59 c           59 g          141 t
ORIGIN      
        1 tttatttgat aatataagat tcccactggg taaattaatg gaagataagg ctactactta
       61 tttgctgatc gatcattccg aaaaagttgc tgtcaattca tctgctaaat atcactatta
      121 ccaaagccct aaaagtatac tgagaggaag cttcaatcct agaatttttg attcttttga
      181 agtccatgaa gatatactaa tattcataga taagttttat ccggaattat caattaatgt
      241 tagaactcgc tatgtctatg aagcaataag gatgatgatg acaatgatta aaaataacta
      301 taccaataaa gaagattatt tacgttctat aaatatttta caacgctttg aaaaagaagt
      361 gaaaattgat cccgactttt caccaaaatt aaaaaaatta gtaaagtttt tattaataaa
      421 taaaaac
//
LOCUS       DADVXM010000209          412 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.228, whole genome shotgun sequence.
ACCESSION   DADVXM010000209 DADVXM010000000
VERSION     DADVXM010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.228"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(2..>412)
                     /locus_tag="KB927_002731"
     CDS             complement(2..>412)
                     /locus_tag="KB927_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBB6841567.1"
                     /translation="GLYYSPVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAP
                     QEYLSRAYNDAPKYCANIVNTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLA
                     ELKGYQVTTGEPVCQTRRLNSRIDKVRYMFNKIT"
BASE COUNT          132 a           78 c           70 g          132 t
ORIGIN      
        1 actaagttat tttattgaac atatatctta ctttatctat ccgactattt agacgacggg
       61 tctggcaaac aggttcgcca gtggtaacct gatatccttt tagctctgct aaacaaacac
      121 taagcccatt tgtaaaaaaa gttaaatcat tgcgataatc ttgaatacat cgagcaggaa
      181 tttctccaat aataatgacc tcattatttt tcagttgagt atttacgata tttgcacaat
      241 atttgggagc atcgttatat gcccgtgaaa gatattcctg tggtgcataa actttaaaac
      301 taagatatgg ctctaacaat tctgttccag cttttctaaa ggcttgctcc agtacaatag
      361 gagtaagcat ccgaaaatct gctggagtac taacagggct atagtataaa cc
//
LOCUS       DADVXM010000210          387 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.232, whole genome shotgun sequence.
ACCESSION   DADVXM010000210 DADVXM010000000
VERSION     DADVXM010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.232"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(72..233)
                     /locus_tag="KB927_002732"
     CDS             complement(72..233)
                     /locus_tag="KB927_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBB6841568.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
BASE COUNT          124 a           84 c           46 g          133 t
ORIGIN      
        1 attaaagttc tatttttctt tcttgtaata tatgctatag cattttttat cactttccta
       61 actactcctt tctattttct tactccataa ctaattgcat ccactggaca agcattttta
      121 catcgtccac atctgataca ctccagatga ttgcaattct caactgaatc tttattcatt
      181 tggcaaactt ttttacattt tccacaatta atacacttat ccttatcctg aatcggctac
      241 actagactag acagaaaaaa taaggtgtgt agaataataa aaaacacact ggaggatttt
      301 tcatgtcaag acgtcaacga agaacctatt caaaagaatt caaacaacaa atcgtcgatc
      361 tctatctcgc tggtaagcct tgcgcag
//
LOCUS       DADVXM010000211          376 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.233, whole genome shotgun sequence.
ACCESSION   DADVXM010000211 DADVXM010000000
VERSION     DADVXM010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.233"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            82..>376
                     /locus_tag="KB927_002733"
     CDS             82..>376
                     /locus_tag="KB927_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBB6841569.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTH"
BASE COUNT          133 a           62 c           76 g          105 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccatt
//
LOCUS       DADVXM010000212          363 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.234, whole genome shotgun sequence.
ACCESSION   DADVXM010000212 DADVXM010000000
VERSION     DADVXM010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.234"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            72..269
                     /locus_tag="KB927_002734"
     CDS             72..269
                     /locus_tag="KB927_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBB6841570.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            271..>363
                     /locus_tag="KB927_002735"
     CDS             271..>363
                     /locus_tag="KB927_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBB6841571.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVL"
BASE COUNT          134 a           35 c           72 g          122 t
ORIGIN      
        1 gaattgtttt ttgaaattta atgaatgtta gaataatagt ctaaaaacat taatttaggg
       61 gtgattagat tatgaaacat ttaaaaattt tgtctattaa agagacacaa cttatctatg
      121 ggggtaccac tcatagtgga aaatattatg gaaatggagt gtattgcact aaaaataaat
      181 gtacggtcga ttgggccaag gcaactactt gtattgcagg aatgtctata ggtggttttt
      241 taggtggagc aattccaggg aagtgctaaa atgaaaaaaa atgctaagca aattgttcat
      301 gaattatata atgatatatc tataagtaaa gatcctaaat attctgatat tcttgaggtt
      361 tta
//
LOCUS       DADVXM010000213          355 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.235, whole genome shotgun sequence.
ACCESSION   DADVXM010000213 DADVXM010000000
VERSION     DADVXM010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.235"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            57..251
                     /locus_tag="KB927_002736"
     CDS             57..251
                     /locus_tag="KB927_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841572.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            241..>355
                     /locus_tag="KB927_002737"
     CDS             241..>355
                     /locus_tag="KB927_002737"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBB6841573.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLE"
BASE COUNT          124 a           59 c           69 g          103 t
ORIGIN      
        1 actaacaaat gcacctcaag atatacttga gctatcaaga agtctggagg ttttctatgt
       61 ataaattaaa tgagattgtt cctgtccaat taggaaacga aaagagtgca ccagaaaaag
      121 gtaaacccgc ggctgccaag ttagcgatgc gcatcaaaag agagaatggt tctgaagttt
      181 tgatctataa cggtattaac aattatattc ttcaagctat tttgaaagaa ctgttgtcca
      241 atgctttatg atttacttca aaccaaacat atttatattg tgtgcggaaa aacagatttg
      301 cgaaaaggaa ttgatggtct tgccagtctt attcaacaag agtatcaact cgagc
//
LOCUS       DADVXM010000214          323 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.237, whole genome shotgun sequence.
ACCESSION   DADVXM010000214 DADVXM010000000
VERSION     DADVXM010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.237"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(34..>323)
                     /locus_tag="KB927_002738"
     CDS             complement(34..>323)
                     /locus_tag="KB927_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841574.1"
                     /translation="TAVSRAYYSAFKKSDEYLKENYDIIYNGSSGKGSHQTVWNLFST
                     VKELNTLGIHNSGYRMLEKRKCADYIPNETITKTDMALMNREAEKIINKLT"
BASE COUNT           96 a           62 c           39 g          126 t
ORIGIN      
        1 aaaaaaataa caaacaaact cgcttgaaat tcattaggtg agtttgttta ttattttttc
       61 tgcttctcga ttcatcagcg ccatatctgt tttcgtaatg gtttcattag gaatatagtc
      121 agcacatttt cttttctcta acattctata cccactatta tgtattccta aggtattcaa
      181 ttccttaact gttgaaaaca aattccaaac ggtttggtgg cttccttttc cgctacttcc
      241 attataaata atatcataat tttctttcaa atactcatca gattttttaa aagcactgta
      301 gtatgctctt gaaacagcag ttc
//
LOCUS       DADVXM010000215          293 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.denovo.239, whole genome shotgun sequence.
ACCESSION   DADVXM010000215 DADVXM010000000
VERSION     DADVXM010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.denovo.239"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(<1..271)
                     /locus_tag="KB927_002739"
     CDS             complement(<1..271)
                     /locus_tag="KB927_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6841575.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSP
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCG"
BASE COUNT           88 a           54 c           51 g          100 t
ORIGIN      
        1 ttccacaatc atggcagaga aaacgggtac gttttaattc taaaatagtt aacttttctt
       61 tgactttcaa catctgagtg cgtgtcgtat aggaaccgtt gcggataata cgaaccgatc
      121 gacagtgttc acaataggaa ggagagtcat ccaattttcc tttaataaac tgcgcttgaa
      181 cgcctttata ttctttttca atcagccatt cttcatcaaa aaataaatgt ttatctgtta
      241 atccgagtaa ttttctagta tgattatcca ttgagagact cctttggtag gat
//
LOCUS       DADVXM010000216        46136 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.guided.013, whole genome shotgun sequence.
ACCESSION   DADVXM010000216 DADVXM010000000
VERSION     DADVXM010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 46136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.guided.013"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..252
                     /gene="tuf"
                     /locus_tag="KB927_002740"
     CDS             <1..252
                     /gene="tuf"
                     /locus_tag="KB927_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBB6841576.1"
                     /translation="LTKEEGGRHTPFFNNYRPQFYFRTTDVTGTITLPEDTEMVMPGD
                     NVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTEIEA"
     gene            complement(440..3031)
                     /gene="mprF"
                     /locus_tag="KB927_002741"
     CDS             complement(440..3031)
                     /gene="mprF"
                     /locus_tag="KB927_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBB6841577.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(3057..3818)
                     /locus_tag="KB927_002742"
     CDS             complement(3057..3818)
                     /locus_tag="KB927_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6841578.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            3985..4617
                     /locus_tag="KB927_002743"
     CDS             3985..4617
                     /locus_tag="KB927_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBB6841579.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            4676..5536
                     /locus_tag="KB927_002744"
     CDS             4676..5536
                     /locus_tag="KB927_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBB6841580.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            5721..8036
                     /locus_tag="KB927_002745"
     CDS             5721..8036
                     /locus_tag="KB927_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6841581.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            8218..10059
                     /locus_tag="KB927_002746"
     CDS             8218..10059
                     /locus_tag="KB927_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBB6841582.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            10083..11192
                     /gene="rpoD"
                     /locus_tag="KB927_002747"
     CDS             10083..11192
                     /gene="rpoD"
                     /locus_tag="KB927_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBB6841583.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            11412..13511
                     /locus_tag="KB927_002748"
     CDS             11412..13511
                     /locus_tag="KB927_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBB6841584.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            13707..14570
                     /locus_tag="KB927_002749"
     CDS             13707..14570
                     /locus_tag="KB927_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6841585.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYGFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            14675..15148
                     /locus_tag="KB927_002750"
     CDS             14675..15148
                     /locus_tag="KB927_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6841586.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            15244..16131
                     /gene="xerD"
                     /locus_tag="KB927_002751"
     CDS             15244..16131
                     /gene="xerD"
                     /locus_tag="KB927_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBB6841587.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            16150..16521
                     /locus_tag="KB927_002752"
     CDS             16150..16521
                     /locus_tag="KB927_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBB6841588.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            16491..17288
                     /locus_tag="KB927_002753"
     CDS             16491..17288
                     /locus_tag="KB927_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBB6841589.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            17272..17841
                     /gene="scpB"
                     /locus_tag="KB927_002754"
     CDS             17272..17841
                     /gene="scpB"
                     /locus_tag="KB927_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBB6841590.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            17847..18563
                     /locus_tag="KB927_002755"
     CDS             17847..18563
                     /locus_tag="KB927_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBB6841591.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      18645..18770
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            18893..19504
                     /locus_tag="KB927_002756"
     CDS             18893..19504
                     /locus_tag="KB927_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6841592.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            19882..21405
                     /locus_tag="KB927_002757"
     CDS             19882..21405
                     /locus_tag="KB927_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBB6841593.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            21642..22982
                     /locus_tag="KB927_002758"
     CDS             21642..22982
                     /locus_tag="KB927_002758"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBB6841594.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            23135..23872
                     /locus_tag="KB927_002759"
     CDS             23135..23872
                     /locus_tag="KB927_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBB6841595.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(24037..24258)
                     /locus_tag="KB927_002760"
     CDS             complement(24037..24258)
                     /locus_tag="KB927_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBB6841596.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            24289..25320
                     /locus_tag="KB927_002761"
     CDS             24289..25320
                     /locus_tag="KB927_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6841597.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            25307..26710
                     /locus_tag="KB927_002762"
     CDS             25307..26710
                     /locus_tag="KB927_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBB6841598.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            26776..27411
                     /locus_tag="KB927_002763"
     CDS             26776..27411
                     /locus_tag="KB927_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6841599.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            27460..28140
                     /locus_tag="KB927_002764"
     CDS             27460..28140
                     /locus_tag="KB927_002764"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBB6841600.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            28275..29504
                     /gene="rpsA"
                     /locus_tag="KB927_002765"
     CDS             28275..29504
                     /gene="rpsA"
                     /locus_tag="KB927_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBB6841601.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            29686..30996
                     /gene="der"
                     /locus_tag="KB927_002766"
     CDS             29686..30996
                     /gene="der"
                     /locus_tag="KB927_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBB6841602.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            31239..31514
                     /locus_tag="KB927_002767"
     CDS             31239..31514
                     /locus_tag="KB927_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBB6841603.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            31749..32795
                     /locus_tag="KB927_002768"
     CDS             31749..32795
                     /locus_tag="KB927_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841604.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            32797..34056
                     /locus_tag="KB927_002769"
     CDS             32797..34056
                     /locus_tag="KB927_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBB6841605.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            34062..34643
                     /locus_tag="KB927_002770"
     CDS             34062..34643
                     /locus_tag="KB927_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBB6841606.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(34725..35600)
                     /locus_tag="KB927_002771"
     CDS             complement(34725..35600)
                     /locus_tag="KB927_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6841607.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            35748..36080
                     /locus_tag="KB927_002772"
     CDS             35748..36080
                     /locus_tag="KB927_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBB6841608.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            36192..37400
                     /locus_tag="KB927_002773"
     CDS             36192..37400
                     /locus_tag="KB927_002773"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBB6841609.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            37554..38009
                     /locus_tag="KB927_002774"
     CDS             37554..38009
                     /locus_tag="KB927_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841610.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            38371..38646
                     /locus_tag="KB927_002775"
     CDS             38371..38646
                     /locus_tag="KB927_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841611.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            38659..40737
                     /locus_tag="KB927_002776"
     CDS             38659..40737
                     /locus_tag="KB927_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBB6841612.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            40897..42783
                     /locus_tag="KB927_002777"
     CDS             40897..42783
                     /locus_tag="KB927_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6841613.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            42795..43742
                     /locus_tag="KB927_002778"
     CDS             42795..43742
                     /locus_tag="KB927_002778"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBB6841614.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            43762..44289
                     /locus_tag="KB927_002779"
     CDS             43762..44289
                     /locus_tag="KB927_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6841615.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(44352..45005)
                     /locus_tag="KB927_002780"
     CDS             complement(44352..45005)
                     /locus_tag="KB927_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBB6841616.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            45137..45979
                     /locus_tag="KB927_002781"
     CDS             45137..45979
                     /locus_tag="KB927_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6841617.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
BASE COUNT        15710 a         7882 c         9758 g        12786 t
ORIGIN      
        1 ttgacaaaag aagaaggtgg acgtcatact ccattcttca acaactatcg tccacagttc
       61 tacttccgca caactgatgt tacaggaaca atcacattgc cagaagatac agaaatggtc
      121 atgcctggtg acaacgtgac gattgatgtt gacttgatcc atccaatcgc tgttgaaaac
      181 ggaacgacat tctcaattcg tgaaggcgga cggacagtag gttcaggtat cgttacagag
      241 atcgaagcat aagaaacgcg actcgaatat tttggtaatg aaaaatgttt aaaataaaag
      301 agcggtccaa acaggatttc tgtttggacc gctctttgtt cttcaattgt ataagaagag
      361 attgtagaag catgaacttt cgttttactt cagtctcttt tattcatcat gagagtgttc
      421 atctatcggt atgcagtttt taatactttc ttcgtatcca ttttttcaaa ccacttattc
      481 taccttgtgt ctgctcaact ggcgcattat caataatcag caaagcaatc ataacatatg
      541 caatccaact atctctagaa tatagagtat aacgtgagac ccagtttgta gcgtacttgc
      601 ttttatattc tcttaatcca tggaaagaat aaaaatgaga accaaactcg taaaccaagt
      661 atgcaatcct ttcctgtaaa aaactctttc tggaagttcc gacatttgaa agaggggcca
      721 tccctaaatt gaaccattgg atatgttctt ctttcatata ggcaaacaaa tgcaagaaca
      781 agaaatccat actgccagaa ggtgcttttt tagaatcata tcgcatcaga tcaatcgttc
      841 ctactttatt gttcgtgtaa gtaggcatga tcgttgcaaa agcgacaatt tcttcttggg
      901 tatttttgac aactgcaata ggcgctcttt gtagataatc ttcagagaaa aagcctaaag
      961 aaaacccttt ttcctttcgt gaacccaacc aattatcaga gatatttttg aaagtactca
     1021 tttgctcagt agaaaatggt ggttgtaaga catcaaatgt aaatccttct cgttcgatcc
     1081 gattcaagac agcacgagtg cccttcattt ttttccctga agttgtaaaa ctattcaggt
     1141 ctacataagc ttcttccccc atcttaatga aatcgtagcc gaattcatgc aaaatcataa
     1201 caatctcttc gcttgtttcg tagaaaactg gtaaatagca tagtcgatct gtttcttcga
     1261 taaaagcttc gattgcttct ggaaaatctt ctttcttacc agaaggatca cccattacaa
     1321 tacatttatt attgaagcaa gcgaattgga gaagaacagt tggttcaccg tctttttcat
     1381 aggcaaacat ccgcttatct tttaagaaga tcaattgact atcggagttt cctccataag
     1441 ttgtaaggat cttcagggcc ttttcttcat taaaggcttc gccaatctgt ttcttttctc
     1501 cttgaaggaa atgaacaaat agaacgatca tgaaactaac agcgatgatg gccaacaatc
     1561 ccgaaaacca aatcttttca gaaggaaata agaaaaagga aataaaatgg tgacgccgat
     1621 gagggaaatc cggcagattg tataccccaa taacgatgta aagcaaggac agtgcaccaa
     1681 taatgattcc atcgatcgta cgccactccc atgaatagat caattgttcc cgaaataatt
     1741 cgtttttaga agcaagaatg atcagaagca gaatagacaa gaaaaccacc ggtgtgaaac
     1801 taaaatcact taataaaaca taaagtaaag ctagaacaat caagaagatt gtaggcaaat
     1861 atgctcgttt cacacgtgct gcgatccctc tgcccataat gattaaaaga aatcccaata
     1921 gtatactagg aaattggata ataaaatgaa atttcaatgg gttcaaacta tgaagccagc
     1981 gaaactctgt aaaagcttgc gggatagtgg cagaaagtac tagcatgatt ccagaaaagt
     2041 ataataagac aaccacgatt ttatgcgcaa tttctgttgc taattgttta gggataccag
     2101 aataacgctg atcaaaagtg gaaccgatat ttttgaagaa aaagacgatt ccaatcaaaa
     2161 acggaatgat gtagtagaac aggcgataga gcaagatcca cacaacgact atttctcttg
     2221 gcacaccaat agcggacaac ccgataatca tcattacatc gaaactccca atttctcctg
     2281 gaatcataga cacgattcct atcactgaag cagcaatgaa taatggaatt gtttgccaca
     2341 gatcaatccg gatttccatt aaataaccaa cagaaaggaa actaaacagg acaccggtcc
     2401 attccaacaa tgaaactagc aatagctgtc cttgagtttt aagtgaggta ccaccaagga
     2461 atcctttctt tttgaaagta gtaaataaaa agacgacagg aaaatataga ccgccgccga
     2521 tcaaccatat ccaatattgc ttcaaaaaag gagcaactgg cgtgaagact acaagtaaaa
     2581 aagaaagcag actgtaaata gaaagtccag ccatcaaaaa caagaaaact ttcgataatg
     2641 cttggatcac gtttctgctc tctttctttt gtccatatag ttcagagcga agccccacac
     2701 taacaaaccc gccgaaaccg gcaatattgt tgatcgtatt gatcagccag cttgtctcaa
     2761 acaggtaacg aggattctgc ttttgttcaa gcatccgatt caaaataata tcataaccaa
     2821 ccataggtaa cacagagata agaccaatca atagcattag tccgcttttc catacaggta
     2881 tagtggcaaa cgtttctcct aattgctgga tagatagagt tttaccgatg gacatcaatt
     2941 caccgacaat aatgacaatg acagaaatca aaaagattgt tttgaacagt cctaggtggt
     3001 ttttcagcca ttgtatggta ttttttaaca aataaatcac cttctattcc taatagttat
     3061 gtttcagaaa gaaattgaag aacttctcga ttgaagcgtt caggatcttt tctagctaat
     3121 tcatgtcctt gttctttcac aagcacaaag gaagcttttg gtatagtttt agctatatac
     3181 aaagaatgtt ttagcttgat tacatctttt tttcccacga tgatcaaagt gggggagttg
     3241 atttttttta aatcattttc tgtaagcccg atgtcatgca gcaaaagttt gataactaaa
     3301 agatttttgc gaagacttgg gcgaaataaa gagagtaacc atacccatgc ataatgaata
     3361 ttactgatga ctctggcaga aaaacgaacg cctttaacaa gcgtgtttcc agaatttaaa
     3421 atcaatcgat gaactttttt agggaagctg ctggcaaata ccagtgctag atttgctcca
     3481 tcactaaatc caagaaaatc tgcctgatcg attttttcca gcaacatgat cgtattcaga
     3541 tcctcggcca ttaactgaaa attcaacata gatgcttcgt ttgtcgaacg accatgtcct
     3601 cggctatcta ctagatacac ggtatagtag cgttcgagta cagggacctg ttctgaaaaa
     3661 aagcggccgc tgccgtcatt gccatgcagt aaaaagagag ggaagccttg accgctcttt
     3721 tcatagtaaa tttcgctccc atctggcatt tttgcatatt tcttttcttt tttcacataa
     3781 tcacctactg tgtaaagtat aacgattata tcagtcattg ggcaattgtt tttactgaaa
     3841 aacaacgatc attttcgtaa gatgtcaaaa aatacaggaa aattcatttt ttcttaaggc
     3901 gtacacagaa atcaaggaag aaatagccaa gaagataaag aaatagtaag ataaaaaaag
     3961 atgtcaaaat aactaggtga tgaaatgaag cgaaaacgat tatctattat ccgtattctt
     4021 ttttacatga tcattctgac ggttattggt gcggtgttgt ttttaggagg aagaacttat
     4081 cgttcggtaa aacgagtgga aagctatcaa atagaaataa caacagctgc aaaaaattat
     4141 catatggaaa actacgagaa tttgatcaag gcgataatat tgaccgaatc aaaaggaaaa
     4201 gggacagatc tcatgcagag ctcggaaagt ctgcatggag aagctgagat cattgataat
     4261 ccagctgaca gtattgatca aggtgtcaaa tatttggcgg aaatgatagt agaagcaaag
     4321 aaacaaggat gcgatttatg gacagctgtc caagcatata attttgggaa agattatatt
     4381 gcctatgtaa aaaatcatgg cggagaaaac acagtagaat tagcagaagc gtattctaaa
     4441 gatgtgctga gcccactttt aggaaatgag gaagggaaac aataccgata ttggcggatc
     4501 cagtccttgc tttacaatgg cggctatctc tatcataatg gaggtaacat gttttatcct
     4561 gatattgtca aaatgaatga aaaaataata gagacctatg aaaaagtctt taagtaaaat
     4621 agcaggaaat gttcaatcat gaataaaatt aaatgaaaga aggagtgcgc aaatagtgga
     4681 aaaaaggcaa aaaatggaaa atcaagaagt ggggtacaca accaaagact ggatgttacg
     4741 gtttgtgaag ggaatgttta tcggttcagg atttatcttg ccaggagtca gcggtggtgc
     4801 attagcagct gtctttggca tgtatgagcg gctgatttct tttttagccc accttacaaa
     4861 aaatttcaaa gaaaatgttt tgttttttct gcctgttggt ctaggcggag tgacaggcat
     4921 ctttctactt tcttttttag tcagtttttt attaggtgcg tatgaaacaa cgatattatg
     4981 gttttttgtc ggatgtatcg ctggaactgt tcctgcgtta tggaaagaag cagggaaaaa
     5041 aggaagagat acttctgatg tgatcatcat ggttgttact tttgttctgg cttatttgtt
     5101 tttattatac ggcgctcaat tatttgacgg gcaagtcgat cagaattttg gaacatggct
     5161 gattgccggc ggattgattg gtttgggtat gatcgtccca ggattgagcc cttctaattt
     5221 tttggtgtat atgggattgt ataaagcgat ggctgacgga tttaaagaag tacgacttga
     5281 agtgattgtg ccgatcggaa ttggtgggat tctttgtgtt cttggattgt caaaaatcat
     5341 ggattacatt ttctcaaagg catatagcaa gctattccat ttcattttag gtgtagtttt
     5401 tgcttcaacg attatgatca ttcctaccga ttacgcggga ttgggagttg ctggggtact
     5461 agcttgtcct gttcttttta tagccggtac agcactaggt tggtggatga gccgtttgga
     5521 ggaacaatat aagtaaagat agattgataa taaaaacagc acacgggtga ttcaaacaaa
     5581 aaggttggca tcttttttgt aaaatcattc gtgtgttttt ctataaattt tataaaaaca
     5641 agttgttttt aatcttggaa cacgctagac ttaaacacgt gattattttt gaaagttggc
     5701 ggaaaatgga gaaaaagaaa atgaatggac ttacacagca agaggtagtt cagaaaatgg
     5761 cttctggcca gcaaaatgac taccaggaag atgcatcaaa aagtacaaaa caaatattca
     5821 gcgataatat attgacgtta ttcaattttc tgaactttgg tattgggatt tgtctgttat
     5881 ttgtaggtgc gtattccaac atggcgtatt tagcaattat tgtcgtcaat atcgttattg
     5941 gaatttatca agaaatacat gcaagaaatc ttgtacggaa attatcgatt gtttcccaat
     6001 cagaagtact agtgatccgg gacggtaaag aacaatcgat ttctactaaa gagctggtat
     6061 taggagattt ggtaaaaatc ggagcaggag aacagatacc agccgattta caggttatat
     6121 ctggacgggc agaagcaaat gaagctcttt tgacaggcga atctgatttg attgtcaaag
     6181 aaactggagc tgaattgctt tctggaagct ttttgacaag cggttctgtc atggctgaag
     6241 ttatccgagt aggtgcagat aattatgctg tccgcttgac tagcgaggca aagactcaca
     6301 aagctattcg ttctgaactt gtagattcga ttcgcaaagt atccaaattc actagtttcg
     6361 tgattattcc tttggggatc atactatttt tggaagcact gttcatccgc gatgcttcta
     6421 tcaaaatttc tgttattgca tctgcagcag ctttgttagg catgcttcca aagggtttgg
     6481 tattgctaat aagtattgca ttaacgacag gggtaaccaa actggcaaaa aaacgaatcc
     6541 ttgttcaaga catgtattca attgaaacgc tggcccatgt cgatacatta tgcttggata
     6601 aaacagggac cattactgaa gggaaaatga gtatccagcg ggtagaagca ctacatccgc
     6661 tgtacgagaa agccatccca gaaattatgg ggacgtatct ggcagaaagc agtgataaca
     6721 acatcactat gcgggctatg agagattatt ttgagctttc taatcggtat gatgtgacaa
     6781 acaaagtcgc attttcttct gatcgcaaat ggggcgcgat ggaatttcca gaactgggag
     6841 tcgtgtacgt aggagcgcct gaacgtttgg tggaagaaga tcggcttccg gacagtctaa
     6901 aaacagccca agcgaatggc tatcgcgtac ttatgttggg gatcgctcca aatcagcaat
     6961 tgaacgaaga aaaaccagca tttgttgagc cggttgctct gtttgaaatc gatgatccaa
     7021 tccgaaaaaa cgctcaagaa acactagctt atcttcatga ggaaggtgtg gatctgaaag
     7081 tgatttctgg agacaatcct tttactgtct ccaatatcgc tagacgtgca ggattaccga
     7141 attatgatgc gtatgtcgat ctttctcaaa ttactgaaga aatggaagtg cgagaagctg
     7201 ctcatcgcta tacggttttt ggacgagtga gtccgcagca aaagaaattg ctggtaaatg
     7261 aattgaaaga aagcggcaga acggttgcaa tgacaggcga cggtgtgaat gatgttttgg
     7321 cgttaagaga agcagattgc agcattgcta tggcagaagg tgatggagca acacgtcaga
     7381 ttgcgaatct ggtattgttg gactctgatt ttactacatt gccagaagtc ctgtttgaag
     7441 gacgccgagt ggtcaacaat gtgacgaaag tctcaggcat cttttttatc aaaacgattt
     7501 attcatttat tttatcgatt atatgtgccg ttacagcaat tggatttccg tttatcccta
     7561 tccaaatcac gctgattgat ttagcgattg aagggtatcc ttccttcttt ttatcttttg
     7621 aacaagataa aagaaaaatc acttaccgtt atttgcctac agcacttatt aatgctttac
     7681 caaatgcctt gcttgtagta gtgaatatca ttgcggtgta tctacttgga aaaacattcg
     7741 catggggaaa tgctgaaact actactttga tgtattactt gctgattggg atcagttgca
     7801 tggcagttgt aaaagcttgt tatcccttca acccattgcg catcttccta gcagtaacga
     7861 cgatcgtagg gatatatgta gctgcaatgc tgttccatgg aattttggaa gtaaacttag
     7921 ggttgggaga gagcgtagga tacttctttg tattcatgct cgtaaatatt gttcttcgag
     7981 tattgtactg gaaggctgat attcaaaatc agttactgaa aagagtagca aattgatgct
     8041 taatgagata gaaatgtgtt atacttgaaa aagcaatgaa atatgataca atcaaacatg
     8101 tataattgtg tcctttaaaa tcgcactgat ttcagttagt gcgatttttt accggttatt
     8161 ctcctgaaat atcttctgtt aaacccaaaa gatatcaata gagcaggggg tgaaaaaatg
     8221 gctcaacgga ttcctcaaga ggttatcgaa acagtacgca gtcaaacgaa tatcgttgag
     8281 gtgattggac aatatgtcca gttgaaaaag tctggtaaaa attacttggg gctgtgtcct
     8341 tttcatgaag aacgtacacc gtctttttct gttgcagaag acaagcagat ttttcattgc
     8401 tttggttgtg gtaaaggcgg aaacgtgttt acttttcttc aagaactaga aggtctaagt
     8461 tttccagaag cagtggtaaa agtggcagac ttcgaacaga taccgttaga agatcaatgg
     8521 cgtcagcgta ctatagctgt ccaaaatcct gaatctgcta cggggaaact gattgctgct
     8581 catgaaaaag cagcggaaat ctatcatcac atgctattgc atacaaaagc tggacagcca
     8641 gctttagaat atttgcaaag tcgtgggttg tctttagaat taattgaaga attcaacata
     8701 ggttttgcac ctaatgagcg ttcttttctt cagcaagtat tcaagaatga atcaatttca
     8761 aatgaattgt tagaacgctc tggattgttt gtcacgcatg atgatggccg tatgtctgat
     8821 cgtttttatc aaagagtgat gtttccactt cgtaattctc aaggccagac gatcggtttt
     8881 tcaggacgct ggcttgcacc tgaaaaaggg caggaaaaag atcagcccaa atacttgaat
     8941 agtccagaaa cagaactgtt caataaaaga caagttttat ttaatcttga taaagcaaga
     9001 agcgatatcc ggaaaaacgg agaaattttg ttgttcgaag ggtttatgga tgtgattgct
     9061 gcatggcagg ctggtatcaa aactggatta gcttctatgg ggacaagtct aacagctcaa
     9121 cagatccaac aaatggaaaa gctgacgaaa gaattggtct tttgctatga cggagacaac
     9181 gcaggttttg aagcaaccaa tcgagggatt gaattgcttc ggcaaaacag tcgattagca
     9241 ctttctgtcg tagtcgttcc agaaaagctt gatcctgatg aatatctccg taagtatgga
     9301 gaagcatctt tccaagaatt agtggctcat gggcgcgaaa cagtctttac ttttaaatca
     9361 cgttatttaa aacaagggaa aaatttagat aatgaaaaag acaagatcga atacctcgaa
     9421 gaattactag ttgaacttag ccgagttgtt tcaccaatcg aacaagatat gtatctatct
     9481 caactgtcaa cagagtttca gatcggcaga gagacgatac aaaaacaact gcgcgatctt
     9541 cgaaggacaa atcagcaaaa tcgtcaagaa cctcaggaaa gtcaacacac tcaggttacg
     9601 agacaagaaa ctgcacggaa aaagagacct ttgacgcaag tagaaaaggc agagcagatt
     9661 ctattatatc gtgcatttaa agaagtttct gtccgtaata ttttaaaaga acgagaattt
     9721 cagtttattc atgatgcata tgcagaagtt tattttttat tcgatgcata tgtctcacaa
     9781 cattatgaat tcaaccttgc agagttttta gactttttgc aagatgaaaa tttaaggcgg
     9841 ttggtggtgg aaatcgaata tttaccggtg gcagaagaaa gttcgccacg agaaatccaa
     9901 gacttgctag atgtgatcag caaatctggc ttagctgatg aaataacatt aaaaaaacaa
     9961 atgcagcaag aagccagacg aactggaaac aaacagcttg agcttgaatt gacgattgaa
    10021 atcatcaatt taacgaaaca gttaaaacaa gccaaatagc tactcaaggg gggccttctt
    10081 ttatggcaaa tggaacagat aaaaaaacgt atgaagcagc agtagcagct ttcatcaaag
    10141 aaaacaaacc caaacgacaa gttgtatatg atgatttatc caatcagctt gctacaccat
    10201 tcactttgaa tgcagatgaa atggacaaat tgatccaaaa gattgaagac gcaggtatca
    10261 gtgtggtgga tgaaaatggt gatccatcaa ttcacagctt gaagagtgct gagaaaaaag
    10321 ctgaacaagc aaaaacagaa gatctttctg cgccaaccgg tgtaaaaatc aatgacccgg
    10381 ttcgtatgta tctgaaagaa attggccgtg tctccctttt aactgcggaa gaagaagtag
    10441 cgttagcatt gaaaatcgaa gaaggcgacc aagaagcgaa acagcgtctg gcagaagcaa
    10501 accttcgttt agtagtaagt atcgctaaac gttatgtagg acgaggcatg cagttccttg
    10561 acttgatcca agaaggaaac atgggactga tgaaggcagt tgaaaaattt gactaccgca
    10621 aaggatttaa gttttcaacc tatgctacat ggtggattcg tcaagccatc actcgagcaa
    10681 tcgctgacca agcacgtacg atccgtattc cagttcatat ggttgaaaca attaataaat
    10741 tgatacgtat ccaacgtcaa ttgctgcaag accttggaag agaacctacg ccagaagaaa
    10801 tcggtgcgga aatggatctt ccaacagaaa aagtccgaga aatcttgaaa atcgcgcaag
    10861 aacctgtttc ccttgaaacg ccaatcggtg aagaagatga ctctcactta ggtgatttca
    10921 tagaagacca ggaagcaaca agtccagcag aacacgcagc ttatgagtta ctaaaagaac
    10981 aattggaaga tgtactagat acattgactg atcgggaaga gaatgtcctt cgcttacgtt
    11041 ttggtttaga tgatggccgg acgagaacat tggaagaagt agggaaagtg tttggtgtta
    11101 ctcgggaacg tattcgtcag atcgaggcta aagcattaag aaaattgcgc catccttctc
    11161 gttcaaaaca attaaaagat ttcttagaat aagcgtggac tattgaccag aagagaaatc
    11221 agtaaaactg tttggtttat tttaaaagaa aaaaagcttg agactacgca gtctcaagct
    11281 tttttttcta taggaaggaa attcattcat tatttttaag taaatcctaa aaataagcta
    11341 ttggcgtgac gtatagaata tgatagatta aatggtagcg taaacctagt aaaggagccg
    11401 atcgctaagt gatgaaaaaa tgtccaaatt gcggatcgaa aaaaatggag cagaatacta
    11461 tctgtccaga ctgcggtcat caaataactg cagaagatca gcaaataaaa gaatcaattg
    11521 aagaaacaaa tacagatgca gctatgcagg ataaatcaac tgaagatgca gtctttcctg
    11581 atacagaatt aaacgatcca atcgaatggt cggaattgaa agatttacct ctagaatctg
    11641 taatggaatt attcgaaaaa gcagaaccag aagacgaaga accacctgct cacgatcaag
    11701 taactaatat agagaaaaat gaacagaaga aagcaactgt tcatgagact tcggaagaat
    11761 caggaaagaa tcaagaagaa acgcttgaat caaaacaaaa aagaagagta gctgaactga
    11821 aagaaatcgt cgataatgag gaagaaaatt cgatactatc cgcttatatc aaagcacatc
    11881 gtgaagatac aaaagaagag cacgcgaaag agctgctcaa aatgatcagt gaaaaaattg
    11941 cacaggaaaa caaagtagag ccagaaaagg aacaagaaac tgaaaaagac tctgatagag
    12001 aaaacgccac aggtaaagaa acagtaaaaa taaaagacgt aaaaacggat atcacagaaa
    12061 aaactgaagt atttactgaa aaacaattag aaaaggaaaa aacgaataaa ctgccggaag
    12121 cagagaaaaa agaaatactc gaaaacacag acaaaaagtc aacagagccc gatgaaataa
    12181 atagtgaatc cgatgctgaa aatcaatctg taagcaaaga gggtactgat cttgaagcaa
    12241 aaatagaaaa agaagagaac cagcctaagc tgtttgaagc agaagcgaaa tcaataacaa
    12301 tcgtgccaga tactgaaaaa acacatcaag aatcaaactt agaaaaaaca gatccagata
    12361 aagcgcaaaa gaaaaaatca aaaaaagtac cttatctcgt tttagcagca gtacttctac
    12421 tcggtggagg aagctgggct tattatgacc atcatcaaaa agtagaagcc gaagtagcag
    12481 cagaagcaaa aagacagcaa caaatggaag aacttcatga gaaacttgct gccttttata
    12541 cagatgatca ccatcaattt attcgtgcag atatgattca tcaagattta tcaaaactaa
    12601 aaaatgattt atccagtctt aagaatgaaa aaggatattc agagttagaa acaacttacc
    12661 aagatatcca atctaagatc cgagatatcc aaaaagtgaa tgagtggttc atagcacctg
    12721 ccatcgtcga tgatcatcta gcagatgaca tcaagttgaa agcagataaa gagatccaag
    12781 caatcgaaac ggataacaca gattttggaa aattgattca acaagcacaa acagaagcta
    12841 aaaatcaata tgctgaattg caaacagcta aagaaaaaac agctatagtc tttaaagacg
    12901 gaaaagtagt ggattcagca acacgcgacc aatacaagac ggcaaaagaa gcagtagaaa
    12961 aagtgaaaaa tacagatcta tctgctcagt tgaatgaaca attgaaacaa gtagataaga
    13021 tgctcactga taaagagaaa aaagaagaag aggaaaagaa aaaagcagaa gaagcgaaaa
    13081 aagcagctga agaacaagca aaacaagccg ctcaagcagc agctgcagct caagccgctc
    13141 aacaagctgc ggtcgcacaa gcagcacagc aagaagcggc atcctcgacc ccttcctctt
    13201 caaactcagc gaatcagcca atcaaatctg ccagagcaag tgatattgcc gatgcatcta
    13261 atccagcatg gacgtgggca ccaggtgtcc aaagcaaagt gattgctaca tgtatccaac
    13321 gtggatatat cgttgaagga ggttacagat tagaaaaagc cagaatcgaa aatggggaag
    13381 gctattataa tctatatgcc acttcaacaa aatctgcatt gatgaaaggc attggagaaa
    13441 gtgctttgcc attttacatc gtaaccatca actgtaaaac tggatggttc ggaggaaatg
    13501 ggagcaatta attttaggca aatgaaagag gctgtgagcc tgccgtttaa caccgtttat
    13561 tcgaaaaagg ggagtatgac acaactgttg tcatactcct tttttcacct ttccaaacca
    13621 aggctcagct attcaagtag ataacattat gttatgatag caaagaaatg tattaagaaa
    13681 acctttcact atagagggag aaaaaaatga acgatttatt agcaactata tttacaggta
    13741 ttattattga tgaaaatgaa aaaaactact ttgtccaaaa aaacggacaa acctttggct
    13801 taagcaaatc agaaggtgaa cacaaaatcg gtgaagcagt tgaaggattc ggttaccaaa
    13861 atcaaaaaca tgaaaatcgg atcactacac aaattcctaa aagccgtatc ggtcattacg
    13921 gttttggaat cgttactgct acacgaaaag atttaggtgc gtttgtcgat atcggtcttc
    13981 cagataaaga ctttgtcgta tctcttgatg aattgccgac aatgacagag ctatggccta
    14041 aaaaagggga tcgcttgatg atttccctta gagttgatgc aaaagaccgt atttggggca
    14101 gtttagcaga tgaaaaaata ttcaaatctt taagcaaata tggaacagaa gaaatgaaaa
    14161 acaaagatgt gataggaaca gcataccgct tgaaattaac aggtacgtac gttttaacgg
    14221 aagatttcta tcttgggttt atccatcctt ctgaacgata taatgaacct cgtctaggcg
    14281 agcagataaa aggtcgagtg attggtgtcc gaccagacgg tgtactgaat ctttcattga
    14341 agccaagagc atatgaagct atatcagatg atgcacaaat gattttaacc attttagaac
    14401 gttctgcaga tcagcaaatc aactttacag ataaatcgga tccagaagaa atcatgaaag
    14461 cttttggtat cagcaaagga gcatttaagc gcgcattagg taatcttttg aaacaaggat
    14521 tgattacaca agaaaacggt gtgacaaaac tagtcaaaaa atctaattga gaatcccttg
    14581 catgtttttc ttaactagct tataataatt ttaattaaca tagtgttata tcttttttta
    14641 tttgtaatta ttataaattg ttggggttga gtaaatggtc atgaatgcta tttcggcgat
    14701 gaaaaaaaca aaacagcagc tacatgaagc ggggtttaag ctgacaccgc aaagagaagc
    14761 tactctgctt gtgcttttgg aaaatgagaa agagcattta tctgcagaag aaatcttctt
    14821 tttagtgaaa aaaaagagtc cggaaattgg acttgctact gtttatcgaa cccttgaaat
    14881 cttgacagaa ttgaaaattg tcgataaagt aagttttaat gatggattag cccgttatga
    14941 tttgagaaaa gaaggcgcca aacatttcca tcatcattta ctatgcttga actgcggcac
    15001 gatcgaggaa gtagaagagg atcttttact tgaagtggag caagtagtag aagaacgtta
    15061 tcatttttta gtaaaagatc atcggctaac gttccatgga atctgtcagg aatgctatga
    15121 aaaagaaaaa agaaaccagt ccgtctgagt gtctagacgg ctttttcttt gctcagatta
    15181 tggaaaaaga ctatcagaat gaagcggtat ctgatatgat agagaggcat gagggggatt
    15241 attatgaaag agcaaatcaa cgattatctc cactacttga atattgaacg gggattgtcc
    15301 gccaatacac gacaaagcta tgaacgtgat ttggaacagt acttgcattt tctacaggag
    15361 cagaaaattg cttcatggca ggatgtcgat cgctttttag tcatccgttt tctggagaag
    15421 ttgcatgaag aaaaaaaagc gacagcaact gttactcgga tgatctcaag tctcagaaga
    15481 ttccatcagt ttttacggca agagcgtatc actgatcatg atccgatgca acatatcgat
    15541 acgccgaaga aagcacagaa attaccaagt acattgactc tgacagaagt agaaaagctg
    15601 attgaagcac ctgatacgac aaaaacgtta gggataagag atcgtgcaat cttggaagtc
    15661 atgtatgcta ctgggatgcg cgtcagtgaa ttgattggat tgaaattggg agatcttcat
    15721 ctttctcttg gactggtaca gacagttgga aaaggagata aagagcggat cattccttta
    15781 ggtgattatg cgatccaatg gctggaacgc tacttagacg aagcacgtcc attacttgta
    15841 aaggacgcat ctgaaatgca tgtatttgtc aataatcatg ggaaaggtct ttctcggcaa
    15901 ggaatctgga aaaatctgaa gcagttagta cgagaggctg ggatttacaa agaagtaaca
    15961 ccacatacgc tgcggcatag ctttgccaca catctgctag aaaatggagc tgatttgcgg
    16021 acagtacagg aattgttagg tcacgcggat atctctacga ctcagattta tacacatatc
    16081 acgaagaaaa gaatgacgga tgtttataag cagcattttc caagggctta gtcataggaa
    16141 ggtgagaaga tgttaacaca ttaccggaaa gaaaaccgta aaattgctat gggactattg
    16201 agtttccata agaaactgac aggtaaaact tctttgttga aggagattga tacgtacgaa
    16261 tctgaagacg attatgaact ttttttcttt acgccagaag gttcaaccaa cattcaaggg
    16321 attattggta tttactgggc aacgaacgat cagctgatca tccatgacat ttctttgaat
    16381 ccgtcttatc gcggtgagaa tatgggcttt caaatgttag atgaattaca ggaaaagtac
    16441 ccggatgtct ccatccgtgc aactgaaatc acagagcctt acattggaaa atggctagca
    16501 aagaaaaaga agaaagagtg aatgagttga cggagatcaa tattaaatta gatgtattcg
    16561 agggtcctct cgatctgctg cttcatctga ttcagcaaat ggaaatcgat atatatgata
    16621 taccgatcgc tacgatcacg gagcaatata tgaattatat ccatacaatg aaaacactcg
    16681 agctagctgt tgcaggagaa tacttagtga tggctgctac attgatggca atcaaaagca
    16741 agacattgct tcctgtccaa gaattcgtca cagacgatga agaattatgg gaagaagatc
    16801 ctcgagaaga attggtcact cagcttttag aataccgtaa atataaatat gcagctgaaa
    16861 gactgacaga aaaagcagag gaacgaagtc tttattacac aaaagaacct atgaacatcg
    16921 atgggttagc ggatgctgaa aagccgttga agcgaggaca agtcaaaaaa atcgatttga
    16981 tccgtgccat gcagaaaatc ttagaacgta agaaattttc tcaaaaagtg gaaaaaacga
    17041 tcacgcccga tgacacaacg atcgaagaac gaatggtatt tatcgaagag cgtataaaaa
    17101 gaaatgcgca tggctgtact ttcgattctt tttttgagtc accttctaaa agtgaagttg
    17161 tcactacttt tatggctttg ctagaattga tgaaaaaagg gcagatcatt gcgcaacaaa
    17221 aagaaaacta tgaatcaatt atgctttatc cagcagtagg agataccgaa catgacgaaa
    17281 ttaagtgaac ttgaagccct tctttttatt gttggcgagg aagggatcag taatgaagaa
    17341 ttaagcggac tgttaaatct cagcgaagca gaagtcacaa gtttagtgaa agaattaaaa
    17401 gaatcttaca ctcaaaactc gcactcagct ttgcatattt ttgaaacgga aagccattat
    17461 gtattaacga ctaaaaaaga gctggctccc ttacttaagc gatatgcgca agggacatca
    17521 aacacattat ctcaagccgc cgtcgaaacc ttagcaatca tcgcttataa acagccaatc
    17581 acaagagctg aaatcgagca gattcgagga gttcaggttt caggagcggt acagcgtcta
    17641 gctgcccata aactgattga agaaaaaggt agagtagaag gaccaggtcg gccgatatta
    17701 tatggaacaa ctggctactt cttagattat tttggtttga aatcattaga agaactgcct
    17761 gatacacaag aaatggaaat ttcacttgaa gaagacgtgt caccagatct attctttgat
    17821 ggaatgaata aaggagaata attgtaatgg agagattgca gaaagtaatt gcccacgctg
    17881 gcatcacttc tcgtcgaaaa gcagaagaat tcatccttgc aggacgtgta aaagtaaacg
    17941 gacaagttgt aagggaatta gggataaaag ttgggaaaca tgacactgtg gaagtggatg
    18001 aagtcccaat ttatcaagaa gaatacggtt actatttatt gtacaaacct aaaggagtta
    18061 tttctgctgt tgcagatgac aaaggaagaa aagttgttac ggatcttttg ccgatggtaa
    18121 aagaacgtat ctatcctgta ggtcgactgg attacgatac ttcggggatc ttgctactga
    18181 caaatgatgg agattttgct cagcgcctga cacatccaaa acatgaagtg gataaagttt
    18241 acgttgcaaa ggtaaaaggg atcgctacaa aatcgatgct tgcacctttg acaaaaggaa
    18301 taaagatcga aggacgaaaa acatctccag ctaaattcca aattttatca gtggatccta
    18361 agacaaacca cagtatcgtg gaattgacga tccacgaagg acgtaatcat caagtgaaaa
    18421 atatgcttca agcagttggt cttcctgtgc aaaaactaaa acgtgaaaaa tacggagatc
    18481 tgactttaca aggcctacgt cctggggatt accgtgaact gaacaaaaaa gaagtcagca
    18541 gtttgctgaa ccactcaaaa tgaacactta ctttttataa gtgttagatg ttgcgttttt
    18601 tgaatagata tgtataatga atatgtaaac aaaaattata taaggttcgt cttcaggggc
    18661 agggtgaaat tcccgaccgg tggttatagt ccacgaccta ttttgcaaaa aaatagctga
    18721 atcggtgaaa ttccgatacc gacagtatag tctggataaa gaagatagag cttatttgac
    18781 gacgcttgat caaataactc taactctatt ttccctggaa aatagagttt tttcatttgg
    18841 agagaaacgt caaaaagttc gctgaagagg agtcctaaca ggaggatttc aaatgaagaa
    18901 cacccgtgta cagaaaatgg ttgcagtagc gatgtttgct gcgatcgcat tagttttaca
    18961 gtattttgct tttccgatca tgccggcttt tagttttttg aagatcgatt ttagtgatat
    19021 ctcggtattg atcagcatgt tcttattcgg tccagcggcc ggagttgcaa cagcgttctt
    19081 gcgttcagta ttacatctgc tgactacagg tttttctccg gataatttgg taggagacac
    19141 tgctagtttc ttatcaacaa cgatctttac attcccgatt tattatttct ttagtgtaaa
    19201 gaaacagcat aaaggaagaa acaaattttt aggtgtcatt acaggaacca tcgctctaac
    19261 tatttttatg agtatcgcaa attatttcgt tattacgcct ctttacttaa tgtttttagg
    19321 gctgaacgca acacagatgc tgggcatgtc tttagcaaac tatgtactga ttgggatcgt
    19381 tcctttcaac ttgatcaaag gattcatcgt gagtgctgtc tttttagtgc tgcatgcgca
    19441 acttcttcca tggttaagtc gaaaacaaca tcagttcgaa caacgtcata cagcagtcaa
    19501 ataaatatca aaaagatcaa gaaatttctt ggtctttttt tttggaaaaa aatacaagac
    19561 atgcaataat gtaaacgttt tatttgtttg ttttgagtat ttttttgatt tatgcataaa
    19621 aatcaatcaa ttctttgcaa atgtgaaatt cttctccttt taaaagacga aaatgtttgt
    19681 ttataaaaaa aaggaaacgc tacaatgaaa aagaagaaag ctttaaaaac ctgaaaaaag
    19741 aggagggaat agggaaaaac gaactttttg aacaaaagtt ttacaaaatg cgtgttatta
    19801 tttttgttct gatactcttt ttgataaaat aacattagag ccaaaattgt tgtctctaac
    19861 ggaaaagaaa ggaagaagaa gatggaacaa acaaaaaaga aaaaatttca aatgccttca
    19921 gcgtatacgg tcttatttat tattattgca gtaatcgctg tacttacttg gtttatacca
    19981 gctgggcact atagtgtaga cgatgcaggc aacatcgtcg ctggatcata tgaacgagta
    20041 caacaaaatc ctcaagggct gtgggatatt ttcatggcgc caatcaatgg gatgctaggt
    20101 gtaccagcgg gggagctaac taaagaaaca cctgctgcaa tcccaatctc tttcttcatt
    20161 ttggttgttg gtggattttt aggtattatc aacaaaacag gggcactaga tgccgggatt
    20221 gcttcagttg tgaagaaatt caaaggaaaa gaaaaaatgc ttattccagt attgatgctg
    20281 ttatttgcat taggcggctc tacttacgga atggcagaag aaacgattcc attctatgct
    20341 ttactgatcc cagtcatgat ggctgtaggc tttgatacag tagtagctgt agcaatcgta
    20401 ttagtagggt ctcaagtagg ctgtctagct tcaacggtaa atccttttgc aacaggcgta
    20461 gcttcacaag ctgttgggat ttcgatgggt gaaggtattg gtcttcgatt cttgatgttc
    20521 gttattttgt tagctatttc tattgtatat gtgtatcgtt atgcatcaaa gatcgaaaaa
    20581 gatccaacaa aatcattagt atacaaccaa cgtaaagaag atatgaagca tttcgatatt
    20641 gaagcaatcg gtcgtcaaga agtaatcacg aaaaaacaaa aacatgttaa tgtattgttc
    20701 tttattactt ttggtatcat gatcatcagt ttgattcctt ggacaacctt gaatgcgaat
    20761 ttcacgattt ttgaatcatt gacaaactgg ttaacaaacc ttccggtact aggtacggtt
    20821 ctaggtaaaa gcatgcttcc attaggtgac tggtacttcc cagaaattac tatgttattc
    20881 ttagtaatgt ccatcgtagt agcaatcact tatggcatga aagagtctga atttgtctct
    20941 gaatttttag ctggtgcttc tgatttgatc ggtgtagcaa tcgtagtagc tgttgctcgt
    21001 ggtatccaag tggttatgaa caatggatta atcacagaca ccatcttaca ttggggcgaa
    21061 caaggattaa gttcattatc ttcaagtgta ttcatcatta ttacatttat tttctatatc
    21121 cctatgtcat tcttgattcc ttcaacttcc ggcttagctg ctgcaacaat gggaatcatg
    21181 ggacctatgg gtgaatttgc cggcgtcggt aaggatttag taatcactgc ttatcaatct
    21241 gcatctggtt tagtaaactt aattacacca acatctgcta tcgtaatggg tgctgtagca
    21301 attgctcgtt tcgatgtttc agtgtggtgg aaatttaccg gtaaattaat tgcgatatta
    21361 tttgtagcca tctgtgtgat cctaggtgta gcagcaatgt tctaaaccta gacaaataca
    21421 ggtacaaggt ctatcataag aatgaagaaa ccgataaacg gctatcgata agcacgtgga
    21481 taagtcaata gctccattca gtgagtgttt tttctttcat catttgttaa gaacattctg
    21541 cttgctgatg gagcaggctt aaaacgtcat tatttgagaa gaagaggttg tgtcggagga
    21601 atttgacatg acccttttta acatattagg aggataatat catgaaaaaa tttgtgacag
    21661 aacaacatca tgaacaagca ttagaatcat tgagcgaatt gatccgaatt ccttccgtac
    21721 tagatgaagc agattcagga caaggacatc ccttcggtaa aaaagtgatt gaagctttgg
    21781 ataaagtatt ggaaatcagt gaaaagctag gatttagaac atttaaagat ccagaaggct
    21841 attacggtta ttcagagatt ggctctggag atgaattatt cggtatcttg tgtcatatgg
    21901 acgttgttcc agcaggggac gaaaataatt gggaaacaaa accattcgat ccaactataa
    21961 aagacggctg gttagttggt cgcggatccc aagatgacaa aggtccttct attgcggcaa
    22021 tgtatgccgt caaagctttg attgatgctg gcgtggaatt caagacacgt attcgtttta
    22081 tctttggtac agatgaagaa aatttatggc gttgtttaga aaaatataac gaaaaagaag
    22141 aaggaattac gcaaggattt gcgccagatg ctgaatttcc tttaatttat gcagaaaaag
    22201 gcttattgca agcttacttg acaggaccag gaacgaacga gttttctgta aaagctggag
    22261 gagcgttgaa tgttgttcct gatgcagctc cttactctgg agaaaagctt tctgaagtaa
    22321 aagaagcatt gaaaaaacac gaattcgatt tcgaagaaca aggtgaaggc atcgtcgttc
    22381 ttggtaaaag tatccacgcg aaagatgcag cacaaggagt gaatgctatt tctcgtctgg
    22441 caattgctct ttcagaagta tttgattttg gcccaatcaa tttcttagga aaattagttc
    22501 aagaaaatgc aactggtgaa gctgtcgtgg gcaaaacaga agatgaacaa tccggcgagc
    22561 taacgatgaa ctttgcaagt ttggaaatca caccagaaca aacaaaaatc ggtgtagata
    22621 tgagaatccc tgttacattc aagaaagatg atttagtagc taaattaact aaaacagcag
    22681 aaaaatatgg gttgacttat gaagaatttg acttccttga ttcattatac gtgccactag
    22741 acagtgagtt agtgaaaaat ctattgggga catatcgcga tattactgga gacatgactg
    22801 aaccgtttgt atcaggcggc gctacttttg ctcgtacgat gaaccagtgt gtggcattcg
    22861 gtgcgatgtt ccctgatact cctgacttta tgcaccaggc gaatgaacga tgggaattaa
    22921 gtagtatgta taaagcaatg gaaatttatg cagaagctgt gtatcgttta tgtgctaaat
    22981 aaaaataaac atacaaaaag ggcggatatt caaatggata ttccgtcttt ttttatttga
    23041 tgctggaaag tttgcatttc tctcttattt ttttaaggta taatcatact tgattaagaa
    23101 aaaggggtca ctcagataga aaaggtggga gaaagtgaaa atatttagac gaatactaat
    23161 tggcttagtc atcattttag gattactcgg tggagccggt tattactata tacagcaaaa
    23221 tacgtacgaa ccatcgtcag aagcgcaagt gttggtaaaa gaaggaaaaa acaaagaaga
    23281 ttacttattt tttgaaggag agaaaaagaa tcatggaaag tctccattac ttatttttta
    23341 tcctggtgct ctcgtagagc cagaaagtta tagtatttgg gcgcaagatt tagcaaaaaa
    23401 cggcttttca gtcgctattg tcaaaatgcc acttgatcta gcagtgatgg gcggaaacaa
    23461 agcggataag gtcaaagaag attttccaaa ttccgattat gtgatcggtg gccattcatt
    23521 aggtggcgta atggcaagtc gttatgtcaa taagaatcat tcagacaaac atttaaaagg
    23581 ggtattcttc atggcaagtt atcccgacaa aaaaggaaca ttgacagaat cagctgttcc
    23641 tgttttatcg atcacggcga caaaagataa agtattgaat caggaagctt atcaagaagc
    23701 taagcagtat ttaccggaaa gaacagagta tgtatcaatc aatggcggaa atcatggagg
    23761 ttttggcagc tatggtgagc aaaaaggaga tggagaggca gaaatttcta acgcagacca
    23821 gcaaactgtg atcgtcaata cattggaaaa ctggctgaaa aagttgaaat aatataaatg
    23881 ggtcctatag ggtccgtgaa aaaactagtc aattaactat agatagcaaa tgaatctttc
    23941 aaaataagtc gggatttcac ggaacaagag aaacagatcc cggcttattt tcaagtttag
    24001 agaacttagt gtacgttttt aaagtttcgt ttatatttat attttatttt ctaataaaat
    24061 cgctcgaact ggacattttt gatacgcttt ttttacatat gtttcttctt ccggcatcac
    24121 gaactgttga tgagcctctg gttcttgggc aaataaaacg attccttctt catcataatc
    24181 gaaaatatct ggcgcttcga tttgacaaag accgcatgca atacagcgtt caggtacaag
    24241 tttacatagt agtgacattt ctaaccatcc taacttaagg agaataatat gattgttttt
    24301 attttatcgc tattttcatc aggacacaag ctgcggatta gttctcttta ccaactcctt
    24361 gtgggaaaac gaacgacttc agtacttatt tatggattta cccacgaact tttgtttatc
    24421 cataacagtt ttccagaatt gaagcaggat aagttttatc aaattttgca aaaaattgcg
    24481 cagcaaggtt ggatcgaaat aaatgaaaat gaagcaaagc taacgcctgc aggggctgat
    24541 atgttgtccg aacatcaaat agaacatact ggtttgcgtt ttgaccgcta tggcagaaca
    24601 ggggaaacta gttggcggct cattaaattt gctgttcaag taatttctaa tctggcaacg
    24661 ggtattcaag actatcttcc agcagagaca agtccttttt atactttcca actaaaaaaa
    24721 tggcttagtg aaagccaatt gccacgtgaa attttgattg atactgcgta tgagagtttg
    24781 gtgcagctgt tttcggagat accagaagaa gcagcagatt ttttagctaa ccaattatct
    24841 ggaaatgagc gaacagggct gcttccttat cagctggcaa aaaacaatga tgagtcagcg
    24901 gtttatctgc aacaaagcag atgtatccac cttttgttag cacaaatcga aaaacggcca
    24961 gattcgcttt ggcacgcttt gatcgattca ttattacagc aaaatttcaa tcaaagcatg
    25021 atgatcacca agcagatgtt tatgaatggt cagacaattg accagatcat ggcaatccgt
    25081 catttaaaaa gaggaacagt aacagatcat cttattgagt gggccttgtt ttttgatgat
    25141 tttccatacg agtggattct ctctgcagaa acaatcgaac gtttggaacc aaataaggat
    25201 tccgtgcgag agtggcgctt tagcgaatgg aatgtagatg gacaattaga ttatggagaa
    25261 tttcgtttgt atcaaatcta tctattgaga aaggaagcga tacagaatgt taataaatga
    25321 attaaaaaaa tattttggat ttgattcatt tcgtcccggc caagaagaaa ttattcaggc
    25381 gttgcttgat ggagaagata ctctcgctat tttgcctaca ggaacgggaa aaagcctttg
    25441 ctatcaattg acggggtatt taatggaagg tctggtcatc atcgtgtcac cgctgctttc
    25501 tctaatggaa gatcaagtga cgcaattaca aaaacgaggg gagaaacgag tagctgcttt
    25561 caatagttta ctttcgcaat ctgaaagaag atacgtcctc cgtcatctat cgcaatataa
    25621 atttttgttt ttgagtcccg aaatgttgac taatccttct cttttagagc atctgaaaaa
    25681 acaaaatatt gcgttatatg tagtagatga ggctcattgc gtgtctcaat ggggagttga
    25741 tttccgtcca gaatatcaac agttaggaaa aatccgaaag cttttaggaa acccggtcac
    25801 actggcacta acggcgacag caacagattt agtagcaaga gatatacgtc atgtactatt
    25861 tgatcgacca ccaaaagaga tcagacaatc agtcaatcgg caaaatatct cgctttttgt
    25921 tcggaaaacg cagcaaaaag aacaagaact tgaacacttc atggaaagag cacaaggagc
    25981 ggcaatcatt tattgtgcaa caaaaaaaga agtcgaacga ttgtatcatt tattcaggga
    26041 acgttttaca gttggatact atcacggtgg tcttgatgca gctcaaagaa gacaacttca
    26101 acagcagttt gtaaaaaatc agctgcagtt tctcattgct acgaatgcat ttggtatggg
    26161 gatcgataaa tctgatatcc gttatgtggt ccattatgat ttgccagaca gtctagaaaa
    26221 ctatgtacaa gaaatcggtc gagcaggcag agatcaggaa gaaagtgcag caattctttt
    26281 ttatcaaagt ggggatgaac gtatccatta tttctttaat caactttcta gagaacagcg
    26341 acaaagtttt gagctttatt tggaatatgc cacagagcaa gctccctttg atgagctgca
    26401 aaaaaaatgg atggagctga tccagcagtc tgaaaaacca gaaaattggg tggaacggct
    26461 caaacgtcag gaaaaagaaa aagaattccg cctgcagcag atgcttcgct atattaatga
    26521 agaaaactgc cgcagaaaat tcatcttagc ttattttggc gaaaaactct ccgaaaagcc
    26581 gcagaattgt tgtgatattg atggagcaaa agcagaactt ctgccaaaga ggaagctttt
    26641 ttctaagact gaacaacttc attgggaaac gattttacta aatttattta aaaaaaacat
    26701 ggaacattga ttttttagga caagacactt tttcctatgg tataatacac acgatagagt
    26761 ttaggaggta aaacagtgag cagaaaagat agacatcaat ctacagaaaa taacgaaaca
    26821 caagaaccat gggaacaacc aatctacgat acagatgatg aagtttcatc aagaagttct
    26881 cagagacaac aaaagaaagg aaatacatta tttctttcgc tatttttgat tttactggtc
    26941 ttatgtatcg ctattccagc aggtgcttat ttctggatca gaaatggatc aagcaacaat
    27001 gcaacagcag caacttcttc tgaaacttcg acatcagtag tagaaagttc tacaagtaca
    27061 acaaaagagg agtcaactga gacttcaaca gtagaatcta gtacaatcgc ggaagaatct
    27121 actgtgtctc aagatacagg tgtaacgtca gaaagcagta ttgcagcaga gacaacaccg
    27181 acttcctcaa gtgaggcaac ttatcaagca ggggattcaa gcagcaatgc agcagaaaca
    27241 acaccttctt catcagctgc agccggttca acaacgactg ttcaagcagg cgaaggtcca
    27301 aaacaagtgg ctgagcgtgc agggatcacc actgatcaat tgtttgaatt gaatggctta
    27361 gatccaaaca actttatgct ttaccctggt caagaattaa gaattaaata ataatagccg
    27421 cgctttgcgg ctttttttct gagaaaaagg agttatatca tgacacaaat cagtattgca
    27481 atcgacgggc ctgcttcatc tgggaaaagt accgttgcca agatattagc aaaagaattg
    27541 aattatattt atacagatac cggtgccatg tatcgcgcag taacttattt agctattacg
    27601 aacaatgtat ctttttcaga tgaagaaggg ctagtttcgc tgatcaaaaa gtatcctatc
    27661 tctttttcgc aacaagaaga tggacagcat gtattcatag catcaaaaga tgtgacttta
    27721 gaaatccgtc aaccagatgt cacaaaagct gtttctgaag tctctgcaca tggaaaagtc
    27781 agagaagaat tagttgctgt ccaacgaaaa ataggggaac gcggtggcgt tgtcatggac
    27841 ggaagagaca tcgggacagc tgtattaccg aatgcagaag tgaaaatctt tttagtagca
    27901 agcgtaagtg agcgtgcaga aagacgtttc aaagagaacc aagaaaaagg aattccgact
    27961 gatcttgaaa cactgacgaa agagatacag gaaagagacc attatgattc aacaagggac
    28021 gtctctccgc tgaagcaagc agaggatgct gttcgtatcg atacgactgg caaatcgatt
    28081 ccagaagtcg ttgcagcaat aaaagctgtt gttttgaaaa aaggttatct tcttttttaa
    28141 attaagaaaa aaaatgaaaa acaattgttt tttcaaggaa aacgaacgaa atcgctttat
    28201 tttttttgaa taatcaatta aactaaaaac agtaccgtac ttacggcaga atgttggtta
    28261 ggaggacaag tgttatgaca gaatttgatc aaaatcaaga gaacaaccag tcaatggaag
    28321 acgcaatgaa aagcgtacaa gaagtaaaag ttggcgatgt tgttaagggc gaagttttag
    28381 tcattgaaga caaacaagtg attgtcggaa tcgaaggggc tggagttgaa ggagtcgttc
    28441 cggcaaaaga attatcaact ttgccggtag aagatatcag cgaagtagta aaagtcggtg
    28501 atgtattaga tttagtcgtt atcagtacga tcggcaaaga taaagaaaac ggcagctatc
    28561 tactttcaaa acgccgttta gatgctaaaa aagtttggga agatatcgaa agagatttcc
    28621 aagagggcaa ggtcatcgaa gcacctgtta caaatgttgt caaaggcggt ttagtcgttg
    28681 acgtcggtgt acgtggtttt gtccctgcat caatggtgga agatcatttt gttgcagact
    28741 tttcagacta taaaggcaaa acattgagct ttaaaatcat cgaaatcgaa ccatcagaaa
    28801 atcgtttgat cttatcgcat aaagcggtag tggaaaacga aagagaagaa aagaaaaaag
    28861 aaattctttc aactatccat gagggagatg ttctcagtgg acgtgttgca cgtcttactg
    28921 attttggcgc atttgtcgac ctaggcggaa ttgacggtct agtccatgtc tcagagattt
    28981 cacatagtca tgtagcaaaa ccaagtgatg tattggctgt caatgatgat gtaaatgtca
    29041 aagtgttgtc tatcaatcct gaacaagaac gtgtttcctt gtcaatcaaa gacacacagc
    29101 ctggaccttg gtcagaaatc gatacaaaag ctccagttgg cacagtatta gacggaacag
    29161 ttaaacgttt gacaagcttc ggtgcctttg ttgaagtgtt ccctggagta gaagggctag
    29221 tccatatctc tcaaatttca cataaacata ttgcgacacc acatgaagtg cttcatgaag
    29281 gtgacgaagt gaaagtgaaa gtattagaga tccatccaga agaacatcgt attgcattga
    29341 gtatcaaagc tttagaagaa aaaccagctt cagaagaaga accaaaaaat gttgagtctt
    29401 atgaattacc agaagaaaat actggattta ctatgggaga cattttaggt gatgcgttga
    29461 aagaagaagt agaagaaaaa gcaaccgatg attctgaaaa ataattgatt ttgtatctgt
    29521 gactgagatg aaagcagctg cttttgtctc agtttttctt ttgaaaagcg attagtattt
    29581 caataaggaa taaaaatact tcgtttaatt gacaatctat gcttgaaagt tggcaatgca
    29641 ttcgttaaac taagtgagat tggaaacttg tgaggaggaa ataatatggc aaatccaaca
    29701 attgcaatcg ttggccgccc gaacgtcggt aagtctacga tttttaaccg catcgctggt
    29761 gagcgtatct cgattgtcga agatactcct ggagtaactc gtgatcgtat ttatgcaaaa
    29821 ggtgaatggt taggtcgaga attcagcgtg atcgacacag gcggaattga tcttggcgat
    29881 gaacctttta tggatcagat caagcatcaa gcagaaatcg cgattgaaga agcagatgta
    29941 atcatttgtg tagtcagcgg acgcgaaggc gtgacagacg cagatgagat ggttgcgaaa
    30001 attttataca gaagtaataa accagtgatt ttagcagtca ataaagtaga taatccagaa
    30061 atgagaaacg atatctatga attttattcc ttagggctag gcgatcctta tcctgtttca
    30121 ggaagccatg gactagggat tggtgatatt ttagatgaag cagtgaagta tttctctgaa
    30181 gagactgaag aagaggacga cgacacgatt aagtttagtt tgattggtcg cccaaatgtt
    30241 ggtaaatcct ctttgatcaa tgcgatttta ggagaagaac gtgtaattgt ttcggatatt
    30301 gaaggaacga cccgagacgc aatcgacacc cacttcgttt ctgaaagtgg tcagaaattc
    30361 ttaatgatag atacagctgg tatgcgtaaa cgcggaaaag tatacgaaaa tactgaaaaa
    30421 tacagcgtga tgcgtgcaat gcgtgccatt gaccgttctg atatcgtttt gatggtactg
    30481 aatgctgaag aagggattcg ggaacaagac aagcgagtag cgggttacgc ccatgaagct
    30541 ggtcgtggaa ttattatcgt cgtgaataaa tgggatcttg taaagaaaga aaccaataca
    30601 atgcgtgatt tcgaacaaga gattcgtgat gaattccggt atcttgatta cgctccaatc
    30661 gtttttgttt ctgcagtgac taaacaacgg ttggaacgtc tgcctgaaat gatcgaacaa
    30721 gtaagtatga accagaatct tcgtatctct tcggctgtgt tgaatgatat cattatggat
    30781 gctgtagcaa tcaatccaac accaacagat aaaggaaaac gcctgaagat tttttatgct
    30841 acacaagtcg ctgtcaaacc acctacattt gtcgtttttg tcaatgaaga ggaattgatg
    30901 catttttctt atgaacgttt cttagaaaat caaatcagaa aagcatttac ttttgaaggg
    30961 acgtccatcc gaattatccc tcgtaggaga aaataggcat tttaccatat cgacgttttt
    31021 ttttcaaaag aaaaagacag tttcgtttgt tacgtttcta tgactaaaaa aagcatgtga
    31081 aaattggtaa aaaccttgct attaagcggt tcatatgata tcgtgataac agaatattga
    31141 agttaatcaa tatttctttt taaacttctg gaccactcag aaagttttaa ctaaatgata
    31201 tttctatcat atctcttgtg gaggaggtga atctatccat ggcaaacaaa gcagaattaa
    31261 tcgaaaaagt tgcttcagct actgatttaa ctaaaaaaga tgcaactgca gcagtagatg
    31321 ctgtattttc aactattcaa gatgctttag ctaacggcga aaaagttcaa ttaatcggtt
    31381 ttggtaactt tgaagttcgc gaacgcgcag ctcgcaaagg tcgtaaccca caaactggtg
    31441 aagaaatcga aattccagct agcaaagtac ctgcattcaa accaggtaaa gcattaaaag
    31501 acgctgttaa ataagacagt tgaaaaagcg cttgtggctc tagggctaca agtgcttttc
    31561 tttttatttc ctagcagaaa aggaataaat aagagacaga gattccgaat ccgtatgtca
    31621 tacatagaaa acacatgtat tttatttaat ttttatttat ttgcaagtta tgaggtgagc
    31681 tttgctctta tcttttctag aatttgctta ctaatggtaa aataaaaata agaagaggag
    31741 ggatgcgtat ggaacttgat tatcaagtag aagatgcgtt gacgaaagtg ttttacggag
    31801 aaacgctagt cagtcagcta agagaacttt ccattgatca gccaatctta tttttaacga
    31861 atcagcgcta ttatgatttg tttgcagata agatcaaccc gttatttgca aatcaagcaa
    31921 acaatgactg gtatatttgt gccaacactc aatgcaatca tttaacagaa ttaaagaacc
    31981 tgcttgattt cgtcaaacgc tatcccgaaa atcaatccat gtttatcatc ggatttggaa
    32041 atgaagggat catggatctg gcaggttttt ttcaaaaaca tacaaccctt gattcatcac
    32101 tatggatgat ccctgtatcg atccgttctc taagccgagc attaacaccg cagcggacga
    32161 ttttgcagct accaaatcgt gtagtgctgc aaaccatcaa tctgccagaa cgcatcgttt
    32221 atgatcaaac aatcagcgag cggcaggtgg acggaaagca gattgacttt ttgactttta
    32281 tctgttgcgg aatgatttgt gatcatcgtt ttttgcaaaa tctgtataaa aactatccaa
    32341 ataaaaagca attaacgact cggccgtttg ccgggatgat cgaagaaatg atctattttt
    32401 atcaattaga ggcagaaaac ctgtcaaatt atggtaaact gtttgaacaa gctttttatc
    32461 tgaccgaaaa tggccatcta ctttctgcta gtatgaaaaa atttttagga atgatgtttc
    32521 atttcgtgtg gaatctccaa gcatatcctt ttgatttcca actaaaaaac ttttttgtgt
    32581 ggctggactt gcttggctat ccaatccact ggctggaaca gatttcaaag atggagtatt
    32641 tggaaaaagt tctttttttg gcagaaaaaa gcaaaaaaat acttgtttta gaaaaaatag
    32701 gtataataga cggataccaa catccaaacg aaaaagaatt attgagaaca atgacggtat
    32761 ttcaacaaat cgtcagtgag ataagaggga attgaaatga atacaaatag cgaaaaaatg
    32821 ttgcaagctt tatcagatga agacttgtca caagcacaaa tctttttaga aaaagcatta
    32881 aaagaagacc cagcagatat attagctgaa ctaggcgaag aattgctggc tattggcttt
    32941 ttgatcgaag caaaacagat ttttgaacaa ctgatcaacc aatacccaga aaatgacgga
    33001 ctgaacatcc cgttagcaga aattgcaatc gaagataatg agatcgactt agcttttgaa
    33061 tacctggaaa aagtggataa gcaaagtgat tactatccgc aaagcttatt ggcgatagct
    33121 gatttgtacc aagttatcgg aatccctgaa gtgagtgaag caaaattgaa agaagcagct
    33181 gggttgcttc ctgatgaacc attgatccag tttgcgctag ctgaattgta tttttcagtt
    33241 gatcgtttca aagaggcagc agtggtttat gaaacattgt tggcaagcgg gataaatgaa
    33301 atttcaggaa tctcgatgca ggaacgttta ggacaatcct taagtatgca aggagaattc
    33361 gaagcagcta tcgtaccttt agaagaagca ctgaaagaag aaaggacaga tgatcgactg
    33421 ttccagctag cttttacgaa tcttcaattg aaagaaaatc agcaggcaat caactatctg
    33481 gaagaacttc gagaagttaa tccgcattat caatcgttat atctatatct aggacaagct
    33541 cttcaagaag aagaaatgat tgaagaagca caaacagtgt tagaagaagg aatcaaagaa
    33601 aatccttacc aagtcgaact ttatcacctg gcctcggaaa atgctttccg tctgcatgat
    33661 agacagcgag cagaagaact tttactgaaa gctttagaag taggagacaa acaagatgaa
    33721 acattactta ctttaagtaa tctttacttg gatgatgaaa gatatgaaga tgtgatacaa
    33781 gtgatcaatc agatggaaga aactgctaat ccttatgcag aatggaacct agcccatgct
    33841 tataatgaat tagaagactt taccgttgca gctgtacact atgaacaggc ttatcatgaa
    33901 ctatcacatg aaccagattt cttgaaagag tatgcctttt tcttaagaga agaagggcag
    33961 ctgaaaagag cgcaagaatt attgacttat tatttaacac ttgaaccagg agatatggag
    34021 gcactgtcat tattagatga cctaacagag aggtgagaaa aatgctaatt gatgtacggg
    34081 aaaagaagaa ttttttaacg tggatggtca atcatgtatc ttttagccga agagaagttt
    34141 tttggatctt gaattatctt gccaatcatg aagcgatttt aagcaatgtc cactttgttg
    34201 aaggggcgaa ttttgcggat cgaggactgc agatcagtga tctatctgtt gaaggggaac
    34261 ccatgaaatt gtttttgcag ggaaaagaat ttacggacac agaccagatt tttcatgaaa
    34321 tccgtttgaa ttggaaaaag cctttatatg tggaatgtat attcgaaaat gcttggcaga
    34381 caagagaata tctatctatc ttagaagaca atccattttc ttcttgggat tcttcagtca
    34441 gtgaagaaga tactgaatta attgaacgat attttcaaga aaaagaagaa gaggcaaaac
    34501 taaaaatgct ttatgctcaa atcgatcaag cactagaaga tggagatagg gatgcttttt
    34561 tgaaattatc tgatgaagtt aaccgaaaga tccttttgca gacacaaaag aaaagtaacc
    34621 gggtaagtga acataacaat tagttaaaaa tagtatagta ctaaaaaaga caaaggtcag
    34681 ctggatgtgg aatctttcct catagcctat ctttgtcttt tttcttatag ttttttcagt
    34741 aatcttgtct gtggcttcaa ataagtaaag ccttgccctt ccacttcatg cacattgatg
    34801 attgaaagga aagctttttc gtcaatctcg tggacgatcc tcttagcttc agttaattca
    34861 ctagagctaa cgaccatata gatgattttt tttgaattac cagagaatgc gccttctcca
    34921 gaaaggaaag tcacacctct ttgcagaccg gtcatcagta gtggtgcaat ctcttcgctt
    34981 ttgttggaga cgacaagtag accttttgca gaatatccgc catctaagat cgaatcaatc
    35041 acacgactga aaacatacga aacaatcaac gtatacatca tacgtttcaa gtcgatatag
    35101 gttaatgaag caagtaagac gatgatatca aatgccaata gggaacgccc catagtgatg
    35161 ccgtaatttt gttctaaaat ccgagcgata atatcactgc cgcctgttgt tccacccatg
    35221 cggtagacga tcccgcttcc tacacctgca actaaacccg caagtagaga aacgatcagt
    35281 agatcatgct gtaaattgat ttctagtgga accctttgcc agatccataa aaagaatgac
    35341 aaagaaagtg tacctagaac agtataggcc aaggaacgtt taccgaggat ctttcctcct
    35401 agtaaaatca atgggatgtt gattaataaa gtcgtataag ctggatcaat accaaataaa
    35461 gctcttaaga tcaaggtgat ccctgagact cccccttctg ctaaatgatt agcgatgttc
    35521 aagtaaacaa gaccaaatgc ataaatactt gttcctataa tgataaaaag aacttctttt
    35581 actgtttttc gtttgaccat atgaattcca gctttcaatt atgtattttc acagaatttc
    35641 catttagaaa ttccttccta aatgtagcat ggaaattcga ttttctcaat tgctcttatc
    35701 taggatttgc gttaaagttt tggtaagata gttttggagg gaaaaagatg gataaaaagc
    35761 gttctttata cagtatgcag caggaagtgg atgaatatat ccagcaattc aaggtggggt
    35821 atttctctcc attagctcag atggctcgat taactgaaga agtaggtgaa ttggcaagag
    35881 aagtcaacca cacttatgga gaaaaaagca aaaaggcttc tgaaccagtt aactcggtag
    35941 cagaagaact tggtgatgtt ttattcgtta cgatgatcat ggctaattca ttgaatatcg
    36001 acttaactga agtttttgaa aaaaacatgg aaaaattcaa tcaaagagac cataatcgct
    36061 ttgagcgtaa ggacgagtaa acaagatgaa gtggtcctgg ccttgaagac tctgaaacgg
    36121 acttgtcaaa cagtcaccat gcaactgagt ctttatctca ggacaagaaa cacgcaggaa
    36181 aggttggaaa aatgaaatta aaacaattac ctctggaata ccaaaaggca attccagttc
    36241 tgaaaaaatt agagaatgca ggatatgaag cttattttgt aggtggaagt gttcgtgata
    36301 tcttgctgaa ccagccaatc catgatgtgg atatcgcaac aagcgcattt ccagaagaaa
    36361 tcaaacagct ttttccaaaa acgatagata ttgggatcga acatggaact gtgttggtat
    36421 tagaaaatga tgaacaatat gagatcacca catttcggac ggaatcaact tatcaggact
    36481 accgtagacc agatcatgtc gaattcgttc gttcgttggc agaagatttg aaaagaagag
    36541 attttacgat caatgcgttt gctttgaaag aagatggaga aatcatcgat ttgttcgatg
    36601 gtctgcaaga tctagaagaa cagatcttgc gagctgtagg caatcctcat gagcggttcc
    36661 atgaagatgc cttacgaatg atgcgcgggt tgcgttttgt cagtcaacta gggttcaaat
    36721 tagaggaaga aaccttctac gccatcaaag aaaaccacga gctattaggt aaaatatctg
    36781 tagaacgtat aaatgtggaa ttcatcaaga tgctcttggg aaatgaacgg gccgcgggaa
    36841 tccatgcatt tattgaaaca gagtgctaca tttgctgtcc cggtttgaaa gaagaaggcg
    36901 aagcactttt acgttttgct gaattaccat ccgtcccatt gaaagaagag agccaagcat
    36961 gggcattatt gatcagccaa ctggatctaa aagaaaatga gattcgttcc tttttgaaat
    37021 cgtggaagtg ttctaaccaa atgattaaag acgttcaagc acttgtccaa ggactacgac
    37081 aacgagaaac tggagctttg gaaccattcg aattgtactt cttaggcaaa aaacatgcac
    37141 tgcaagtaga agaattgatg atctattttg acgaaacacc tcagatggat gccgtaggag
    37201 aatcctatga tcgtttacct atcaagtcat taagcgaatt agcagtagat ggtaaaatct
    37261 tgctagaaga aactggaaaa aaacctggta agtgggttag tgaagctttg caattagctg
    37321 aaaaagccgt cgtagaacaa agaataaaaa atgataaaaa acaggttttg gattttttat
    37381 cgaaagaaaa attgatttaa aaaacactag actgtatctg ctcagctttg ttggctactt
    37441 aaagtgggca gatacgtcat tagaagaaaa aacataagat gtgaccactt acataaattt
    37501 gtgctaaact gaggtagtac aagaataaat tacatcataa aggagtcttt ttaatgagta
    37561 aagaaatgac agcgctaaaa ttttatttta gaaatggaga aacctggacg atcaaccgcc
    37621 gtcatatcgg cgatctttgg atcaaacaaa tcacaacaag ttttggacga atcaatggca
    37681 gtgaatttgt tgaaatccat ccgtgtgctg gatttaaaat cgaaatcttc catgaagggg
    37741 acgcagttgc gacacatgat atcaacctag gcggactgga aatgggcatg tttaatcgcg
    37801 cattgaaata cgaagatatc gagcgaatgg aaatccttta ccgaaatggc acacctgatc
    37861 ttgtgtactt cccatatcta gataaaggaa cagaaggatt agacaatcaa tatcaatcaa
    37921 caaaaatcag cgaaaaaaca ggtaacttgt atatcgtgat caatccagat caacgtgtag
    37981 aagatgtata cggggaattt ttcgaataaa tcgattttta cgcaaaaatg aggctgtgaa
    38041 agagatgtgt cttattacta ctgataggct gtctcttcca caccgtttat tcagaataag
    38101 ggactgtgac aagatttttg tcgcagcccc atttttttgt tgtgataaaa gaacaagaaa
    38161 ggcaggaatg ggaaagtaaa catccttttg tcagaaactt ttatctttct taagttttac
    38221 ttgatatctg atactatttg gaatagaatg aggcgttgaa aaatttatgg aaatttctaa
    38281 ctagcaataa acgatgaaac aatgaaatat ttttcatcca aaaagaactt tgctataatg
    38341 atggaagttt gtgtatagga gatctggaaa atgagagaga gttttgaaca acaaaaaaaa
    38401 ctgttgcatg atcgctatgg cgccctttcg atggatgacc gccgtcaaat actttgtaag
    38461 ttgcgtaaaa gaaatatatt gatgtatcgt cagttggaac gtctgaaaca tgatctgctt
    38521 cgtttggagt caaaacgtgt acagtgtgaa ttagagggga accaaacaca ggttgaagta
    38581 gtcgaaacca aaattttaaa gaaaaaagaa caatttttaa aaatgcttac acaaaataaa
    38641 aaataaaggg gatggacgat ggaatttgct gagttagtta ttgtatttgc agtaacgatc
    38701 accttatcga acatagctag ccgcattttg ccaatgattc cagctccact gatccaaatt
    38761 ttccttggag tggtattagg tctgacagag tggggacaat caatcgattt tgaacctgaa
    38821 ttgttcttag ttatgattat tgcaccattg ttatttagag aaggagaaaa agcagatatt
    38881 tcttcgattc tcaaaaattt cgggacaatt ttgttcttgg catttggagg agtcattttg
    38941 acccttgtcg gggtaggtgc gacgttatca ttcctgttgc caagtgtccc acttgctgcc
    39001 tgctttgctt ttggagcagc gttaggtccg acagatgcgg tagcagtcag ttctctttct
    39061 ggacgagtga atatccctaa aaaggcgatg catattttgg aaggagaagg tcttttgaat
    39121 gatgcatctg gtgttactgc cttccagttt gctcttggtg cgctgatcac cggatctttt
    39181 tcagcagtaa acgcggggat gagtctagta gtttctagta ttgggggagc tttgatcggc
    39241 tttttgcttg tctggttcaa acaaaaaata attcatttga tcgaaaaagc atcagcacaa
    39301 gatgtcacag ggtatctgct gatcgaactt ttgcttcctt ttctagccta tgtattggca
    39361 gaggcatttg atgtatctgg aatcattgct gcagtggcag caggtattct ccaagcttct
    39421 ggttttagga aaatctctgt gtttgatgca gaattgtcga gcttgtccca cagtacatgg
    39481 acaactattg cttttacact gaatgcatta gtatttatat ttttaggaat cgaattgacg
    39541 caagtgttct cgccagtatg gggagacggt ttatatccaa acggtctttt attagcgatt
    39601 atcgtattaa tctctgtcat gctttttgtg atcagattca tttctatcag tcttttttat
    39661 gtattcaaag atggcagtaa aaagttcaaa aaacagttga acgagatctt gatcttaaca
    39721 tttggcggtg taaagggaac agtcagtttg gctacgattt ttattttgcc attttcaatc
    39781 aataatatga tgttttacca gcggtctttg cttttgtttc tgacggcggg tgtcatctta
    39841 gtgactttgg tcatagggat cattgtcttg cctatgctga cggaaacaga ggaagcgaaa
    39901 agcacggatt tgaatgcttt gatgatttta gaagaggtcg ttgaagtttt gcgaaaagaa
    39961 ataaaggaaa ttgatcgtaa tacaaaagaa tttttagcca ctgaagcagt gatagaaaat
    40021 tatcaagaac ggatacgtga tctgtacttg gaagatttaa ccgatgatga aaagcaagaa
    40081 gtacaagaaa tacaagcact gattttgtcg atcgaacggg atggattgga tgaaagttat
    40141 cgttcgggca agctttcttc taatggttat cgtttttact cccgttttct ttctcgattc
    40201 gaacattcta tcacaagcca gattttgtct tttatcggct tttggttcat tgttgtccgt
    40261 aggttaatgc gaatcgttct ccatccgaaa atgttttggc aaagaagata tgctgatcgt
    40321 cagacattta ttagtgatga agatatccaa gaaatcagag agacatatca aaaaaatact
    40381 cagttgatta ttgaaagttt agataacttg actgatattt atgatgaaac gatggttcaa
    40441 ttttttatcc agcaacgcaa acttgaagga ataaaaatga actcggggaa tttgatttct
    40501 tcgtggatga tccagcaaga tagtctgttt acgaaaaaaa tgctaagagg ttattatctt
    40561 gaaagaaaaa tcattgatga atacgaagtt gctgaaaaaa tcacgacgtt ttctgcgaac
    40621 agctatcgca ggaatatcaa tttgttagaa tcttatacga tgaacaaacc atctgataac
    40681 ttttctttcc gatttgcgtt tcgagcaaag tcaaaaaaaa cgagtccaat aaaataaaaa
    40741 ggtaaaaatt ttcaagtttt ataaaaaaca aaacatatca gaacaggatc gaatcggtcc
    40801 tgttcttttt ttgagaacac aaaaagaaca aataccaaaa aaattttcct gaagttcact
    40861 atttttatga tacaatatcc aagataagga gggaacatgt tgaaagaatt aaaagtaact
    40921 gacctcaaaa aaacttatgg tgaaaaagat ttgtttgacc agatttcttt tttggtccac
    40981 gaaaaagacc gtatcgggtt gattgggacg aacgggacgg gtaaaacaag tctcttaaat
    41041 attattgccg gtatcgatag cagcgacggt gatcggcaaa cagtgtttta tccaactgat
    41101 taccgtattg gttatctttc tcaagcagct gaattttccg atgaattaac tgttctccaa
    41161 gcagtctttc aaggaaacag ccccttgatc caaactgttc gagcatatga ggaagcattg
    41221 atcgaactag gggaaaacgg agaagaccct gatgtgcaaa aacgttatgc taaagcagaa
    41281 gaacaaatga ataaagaaga tgcttggact acagatacca acgcaaagat tattttgcaa
    41341 aaattaggaa tcagtgaatt agataaaaaa atcagtactt tatcaggtgg tcagaaaaaa
    41401 cgagttagtc tggcgcaagt gttgattgat gaacccgatt tactattact agacgaacca
    41461 acaaaccatt tagattatga agcgatcgag tggttggaaa actatttgaa acaataccgt
    41521 ggcgcactat tgatggttac ccacgatcgt tattttctag atagagtagc aaaccgaatc
    41581 ttcgaacttt catttggaaa attatacgag tataaaggaa attatgaagc ttacgtctta
    41641 gaaaaagcag aacgtgatcg tgtagaagta gaacaagaag aaaagcgcaa gcggctttat
    41701 aaacaggaat tagcttggat gagggctggc gtacaggcac gtggcaccaa gcagcaagca
    41761 cggatcaacc gtttcgaaga tctaaaggag aacttgtacc aagtaaacca agaagatgat
    41821 ttagagctga acctagcgac acaacgttta gggaaaaaag tactggaaat caaagatggc
    41881 agttaccgta taaatgacca aacactgcta gaacatttag atttattgat tcaatctcgg
    41941 gaaagactag gtattactgg taaaaatggt gcgggaaaat cgacattgct taatattcta
    42001 gctggcagaa ttcccctgga tagcggtaca atgtctatcg gtgaaacggt tcatcttgcg
    42061 tattatacac aagaaaatga agaaatggca ccagataaac ggatgattgc ttacttacaa
    42121 gaagctgctg aagaagcaaa aacagcagat ggcagtcaaa tcggagtagc agaattactt
    42181 gaacgatttt tatttccaag atttatgcat gggacactga taggcaaact ttcaggcgga
    42241 gaaaaacgcc ggttattttt gttgaaactg ctgattcagc aacctaatgt tttattattg
    42301 gatgaaccga ccaatgattt ggacatagca acattgacga ttttggaaga ttattttaga
    42361 agttttccag gtgctgtgat cactgtttcc catgaccgtt atttcttgga caaggtagca
    42421 gataagttat tagtattcca aggaaacgga aaacaagaac tttattacgg aaacatgtcc
    42481 agttatttac tgaagcaaaa agagacccag cagcctgctg aaaaagcgaa accaaaaata
    42541 cagagcaagg aacctgctga aaagaagaaa ttatcttaca tggaacaaaa agaatgggaa
    42601 acgattgaag atgagattgc agaacttgaa gaaaaaatct cattgctcca agaagagatg
    42661 aatcatcaag gagataattt cactcgatta caagaattgc aaaacgacgt atctgaaaca
    42721 gaagcacaac ttgaagaaaa aatggcacgg tgggaatact tgagtgaatg ggtagaagat
    42781 taggaggaaa aaggatggaa caagcgtatc ttgacttagg aagaaaattg ttggaagaag
    42841 ggcatcgtaa agaagacaga acaggcacag gcacattaag cttattcgga taccaaatgc
    42901 ggtttgatct gcaaaaaggg tttcctttgt taacaacgaa acgagtacct tttggattga
    42961 tcaaaagcga attgctttgg tttttaaaag gagatacgaa tatccgctat ctattacaaa
    43021 ataaaaacca tatttgggat gaatgggcat ttgaacgcta catcaaaagt ccagactata
    43081 atggaccaga tatgactgat tttggccata gatgtttgac agatcctgaa ttcaatgaag
    43141 aatataaaaa gcagagcaag cttttttgcg agaagatcct aaccgatgat tcctttgctg
    43201 aaacatacgg cgatcttgga cacatctacg gctatcaatg gcgtcactgg gaaacaaaag
    43261 acggtggctt tatcgatcaa atcaaacaag tgatcgaagc aatcaaaaag actcctgatt
    43321 ctagaagatt gatcgtttct gcatggaatc cggaagatgt tcctagcatg gctttgcctc
    43381 cttgtcatac gatgtttcaa ttttatgttc aagagggacg gctaagctgc caattgtatc
    43441 aacgcagtgg ggatgtgttt ctaggcgttc cgttcaacat tgcaagttat gcgttgctga
    43501 ctcacctaat tgcacatgaa acaggtttag cggttggcga atttgttcac acattaggag
    43561 atgctcatct ttatatcaat catatcgaac aaatgaaaga acaattgagc cgagaaatac
    43621 gcgcatttcc gactttagtt ttgaatcagg aaaagcagtc agtatttgat tttgagatgg
    43681 aagatatcca attagaagga tatgacccac atccggcgat caaagctcct atcgctgttt
    43741 agaatcagaa aggatgagaa aatgttagct gcaatttggg cacaggatga aaacggattg
    43801 attggaaaag aagaccgtct tccttggcgt ttgccaaatg atctgaaatt cttcaaacaa
    43861 atgacagaag caaatacact agtgatggga cgaaaaacat tcgaagggat gggtagccgt
    43921 ccgttgccga atcgtcagac gattgttttg acgagagatt cttcctataa agcagaaggc
    43981 gtgcatgtca tgcatagtgt ggaagacgtg cttgctctgg aaaaagaaac agacggtatc
    44041 tttttcatcg ctggagggtc agctgtttat caagaatttc tgccattttg tacgatatta
    44101 taccgtacag tcatccatca tgtattcgat ggagatgctt attttccacc tgttgactgg
    44161 tctgattggt cactgatcaa tactagtcaa ggagaaatgg atgaaaaaaa tcgttatccg
    44221 catcaatttg aaacgtatca gcgtaatgag aatcctgtaa aaagcgggac aggcgaattg
    44281 acgatataaa aaagctatgg atagactagc tgttatttag agctgtccca tccatagctt
    44341 tatttttttt attaagtaaa gaataaaaca gagaagtaca taaaacctgc acctaacata
    44401 acaaacaaat gccaaacaac atgcatatag cggatagaat tcaagctata aaagaatgcg
    44461 cctatcgtgt aagaaagccc gcctgctacc atcaaaataa caccagtcat tccaagagag
    44521 tgataaagag gaacagcagc cacgacacag agccacccca taaaaatata gatgatcgta
    44581 gatacttttg atactctctc ccgtttatgc aacgtcaacg ctttatatat aatgccaaga
    44641 atcgcaaaca accagattaa tacaaataaa gtccaaccta gccatcctcg gatactcagc
    44701 aaacaaaaag gagtataact tcctgcaatc aaaagaaaaa tcgaactatg atcgaatact
    44761 tggaacacct tttttgcttt tgtaaaaatc aatgaatgaa acaaagtaga cgttaaaaat
    44821 aaaagaatca tcatcgatcc atagatagca taagagacaa tatggaggga ggaatgcaag
    44881 tgggcacctt ttactaaaag aaccactagt cccgcgatac tcaatccagt cccaattcca
    44941 tgggtgactg cattaaacac ttcatttaat atttcatacg ttcgattaaa tttcgttttt
    45001 tccatgaaaa cggctccttt actaggtgta attaatgaaa aatcattatt tgtctgttat
    45061 actaaaaata gaaattgtct tacatgtagt ttaacatgaa taaggcatct tgttaaagaa
    45121 agagagagag aaaataatga caaatgtaaa aatcgtaaca gattcttcat gtacgatgga
    45181 aaaaaatgta cgcgatgctt taggcattcg tgtcatgccg ctatccatca tgatcgacgg
    45241 aacagtatat cccgatgatg accaactaga cggcgaaaga tttatggaaa tgatggcgaa
    45301 agcaaaaaat ctgcccaaaa caagccaacc accaattgga gaattcatct cgatgtatga
    45361 tgagctagga gaagacggca gtgaagtgat ttcgatccat atgacaaaag gcttgagtgg
    45421 aacagtagaa gcagcaagac aagccagtaa tctaacaaaa acgaaagtaa cggttatcga
    45481 cagtgatacc actgaccaag gattatcttt tcaggtaatt cgagcagctg aattagcaaa
    45541 agaaggtaaa acagtagaga aaatccttga agaagtcaaa aaagtacaag acaatacaaa
    45601 attatacatc ggaatatcca cactagataa cttggtaaaa ggtggaagaa tcagccgaac
    45661 aactggtttg ctgtctagtg ttttgaacat acgcgtggtg atgaatttcg cccattctga
    45721 attaatccct gtaactaagg ggcgaggaaa gaaaacgttc gataaatggt ttaataattt
    45781 gaaaaatgaa ctgaaagaat tgccaaatgt gcgacaaatc ggtatttcac atgcggatgc
    45841 aaaagaattg gcgcaagaat tcaaagaggg tttgcaagaa ttattcccgg acatgcatat
    45901 ccctgtactg catacgaatc cggttatcgc tacgcatact ggtaaagacg cgtttgcaat
    45961 catgtattat gtagattagt cgaaaagagg ataagccctc agcctgaaag gcttgcagct
    46021 tattctcttt ttctttataa aattaggaaa ataattgttt tcttttttca taaagactac
    46081 ctttttgata aaatttttga taacattaga accaatcgaa tacaagaggt gaaaaa
//
LOCUS       DADVXM010000217        20984 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.guided.043, whole genome shotgun sequence.
ACCESSION   DADVXM010000217 DADVXM010000000
VERSION     DADVXM010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20984
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.guided.043"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            complement(134..577)
                     /locus_tag="KB927_002782"
     CDS             complement(134..577)
                     /locus_tag="KB927_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBB6841618.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="KB927_002783"
     CDS             complement(795..2135)
                     /locus_tag="KB927_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6841619.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="KB927_002784"
     CDS             2404..3300
                     /locus_tag="KB927_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBB6841620.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFNMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLAYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPIPSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="KB927_002785"
     CDS             complement(3450..4391)
                     /locus_tag="KB927_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBB6841621.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFRSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKTAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4516..5637
                     /locus_tag="KB927_002786"
     CDS             4516..5637
                     /locus_tag="KB927_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6841622.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPHGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5895..7397
                     /gene="eat(A)"
                     /locus_tag="KB927_002787"
     CDS             5895..7397
                     /gene="eat(A)"
                     /locus_tag="KB927_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBB6841623.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKSQPKHLSISYVRQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7425..7991
                     /locus_tag="KB927_002788"
     CDS             7425..7991
                     /locus_tag="KB927_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6841624.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8202..9263
                     /locus_tag="KB927_002789"
     CDS             8202..9263
                     /locus_tag="KB927_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6841625.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9266..10162
                     /gene="murQ"
                     /locus_tag="KB927_002790"
     CDS             9266..10162
                     /gene="murQ"
                     /locus_tag="KB927_002790"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBB6841626.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10176..12158
                     /locus_tag="KB927_002791"
     CDS             10176..12158
                     /locus_tag="KB927_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6841627.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSAATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12223..12669)
                     /gene="nrdI"
                     /locus_tag="KB927_002792"
     CDS             complement(12223..12669)
                     /gene="nrdI"
                     /locus_tag="KB927_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBB6841628.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12880..14304
                     /locus_tag="KB927_002793"
     CDS             12880..14304
                     /locus_tag="KB927_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6841629.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14485..15258)
                     /locus_tag="KB927_002794"
     CDS             complement(14485..15258)
                     /locus_tag="KB927_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6841630.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15255..16160)
                     /locus_tag="KB927_002795"
     CDS             complement(15255..16160)
                     /locus_tag="KB927_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6841631.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16314..16634)
                     /locus_tag="KB927_002796"
     CDS             complement(16314..16634)
                     /locus_tag="KB927_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBB6841632.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            17108..17794
                     /locus_tag="KB927_002797"
     CDS             17108..17794
                     /locus_tag="KB927_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBB6841633.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17796..18740
                     /locus_tag="KB927_002798"
     CDS             17796..18740
                     /locus_tag="KB927_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBB6841634.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18939..19583
                     /gene="pcp"
                     /locus_tag="KB927_002799"
     CDS             18939..19583
                     /gene="pcp"
                     /locus_tag="KB927_002799"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBB6841635.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19662..20939
                     /locus_tag="KB927_002800"
     CDS             19662..20939
                     /locus_tag="KB927_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841636.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         6769 a         3786 c         4366 g         6063 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggtgttccag
       61 aagtagcttc ttcttatttc ttgaagctga tcacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg gatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgt caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gttccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaataacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat ggctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgattagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccgccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa gcgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttaat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat ggatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttgcttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ctatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc ttttaagcca
     3181 atcccatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaataaataa
     3301 aaaacctaca ttttgaagag attatgtacc gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttc attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaacgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc taatatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gttttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cattatggct atagatcgga tttaattttg cttcttgaaa gacttccaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacgaaa catatcatct
     4141 aattgattcg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtgt gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc tccagctatt
     4381 gcgattttca tgttttttct ctcctttatc aatgagttcc cttttagtat atagaaaaat
     4441 ggaagaaaat agcattgttt tgtttgaaaa aaatgaaaaa aagtgtctta cttaagaaga
     4501 aagtgaggga tacagatgga tattttggcg gcaattgatt catttaaagg aagtgcttct
     4561 tcatttgaac taaatcaggc agttctaaat ggctgggaag atcgtaaagg aagaaaaatc
     4621 aatgtgccga ttgcagatgg cggagaaaat actgcagaag caatctatta cgcgctcggg
     4681 ggaacatggc gcaccattga tgggatggat cttttattcc gtcagcgaaa aatcagctat
     4741 ttattgacaa cttggcaagg aaaaaatacc gcagtcatcg aatctgcaca agcattgggg
     4801 ttagatctac ttgataaacc aacggatcaa actatccgac ttgcttccag ttatgcctta
     4861 ggagaactta tcaaagatgc actgcttcaa gaagtagaac aaattattgt cactttagga
     4921 ggaagcgggt gtagcgatgg tggtctagga ttactccaat ccttgggtgc ttctttagaa
     4981 gggtacacag aaggaaatcc tttattatct actaaaaaac ttcattttga tcgaagaaac
     5041 gttcttgttt ctaaagtaaa attgattatc gctgcagatg ttaccaatcc atatacaggt
     5101 caacaaggag ctgcttggca atttggaaga caaaaaggag gaatagatac gacgctagct
     5161 ttcttagata aacaagcagg aaagattgct cagcaaataa aagatttctg ggaggtggat
     5221 ttagatgata ttccaggaag tggagcagca ggcggtattg gtggagccct ttttttgttg
     5281 ggagcgaaga tggtttctgg tttcgattta gtcagccaaa tcactggatt ggaaaaaaag
     5341 atcgaacaag cagatgtcat cattacagga gaagggcgga tcgatcagca aacgatccac
     5401 ggaaaagttc cacacggtgt agcagtgctt gcaaaaaaat atcgaaaacc aataatcgct
     5461 atttgcggaa gtagagacca agagctagaa ggactctctg attttctccc aattgtctta
     5521 agtattcatt tgggtccaat aggtttagaa gaagcaatgg aacacaggca aacattagaa
     5581 aaaacaaaaa tcttaggaca gacacttagc agatttttca ccatcctccc gaagtagttg
     5641 acaaaatcat tttctttatg ctatcgtaat ttcaaatata ggacaaagtg agggatccgt
     5701 gcattgaaaa attaagtcga ttgatgaaag ctgcattcag actgtacctt gtggagacaa
     5761 ggaagcagtg tgcagatttt cgggattggc ttggtttttt cgatgtatgg gtctttttgt
     5821 gtgtatccaa cccttgcatc ctctttagcc agttctgaaa ataggactgg tcttttttta
     5881 cgaggtgatg gaaaatgtct aaaatcgaaa taaaaaatct gacattcggc tacgacagcc
     5941 aaggcacatt attatttgaa caagcaaatc taaattttga cacacaatgg aaactaggac
     6001 ttatcggacg aaacggtcga ggaaagacaa ctttactgaa tattctacaa aacaaactac
     6061 cttatcaagg gcaagtaatc catcagcaag aatttgccta tttcccgcaa cagacaaaag
     6121 ataaagaacg tttaacctat tacgtgttaa atgatattac ggattttgag atatgggaaa
     6181 tcgaaagaga gctccaattg atgcaaacag atcctgaaat cttatggaga gaattcagca
     6241 cactatcggg gggagagaag acaaaagtcc tactggcact tttatttgtg gatgacactc
     6301 atttcccgtt aatcgatgaa ccaacgaatc atttggatat ctctggtaga aaacaagtag
     6361 cggcttattt gaaaaagaaa aaacaaggct tcatcgtggt cagccatgac cggggattta
     6421 tcgatgaagt agtggaccat gttttagcaa tcgaaaaaag tcaactggaa ctttatcaag
     6481 ggaatttctc tatctatgaa gaacagaaaa aacttcgtga tgaatttgaa atggctcaaa
     6541 atgaaaaatt gaaaaaagaa gtcagtaggc taaagaaaac agcagctgaa aaagccgaat
     6601 ggtctcgttc ccgagaagga gataaaacaa agaaacaagt cggattcatc gatactgaat
     6661 ctagacgagt gaataaagga gcagtgggtg ctgatgctgc acggacgatg aaacgatcca
     6721 aagcaatcgt gaatcggatg gagacccaga tcagcgagaa agaaaaacta ttaaaagata
     6781 tcgaatatat cgattctttg acgatgaata gccaagcgtc tcaccataag cgacttttaa
     6841 gcgtagaaga tcttcaatta gggtatgaaa atctgttatt cgagccaatt cattttacaa
     6901 tcgagcctca tcagcgggtg gcgatttcag gtcctaacgg tgcaggaaag tcatccatta
     6961 tccattatct tctgggggca ttcaacggca aggttatagg agaaaaatcc cagccaaaac
     7021 atctgagcat tagttatgta cgccaaaatt atgaagacaa tcgaggaacg ttggcggaat
     7081 ttgcagagaa aaaccaagta gactaccaag catttttgaa caacctccga aagcttggga
     7141 tggaaagaga tgtttttcat aacaagatcg agcagatgag tatgggccaa cggaaaaaag
     7201 tggaattggc taaatcttta tcacagccag ctgaactata tacatgggat gaaccattga
     7261 attatttgga tgtcttcaat caagaacaat tagaacaact gatcttgaac gtgaaacctg
     7321 ccatgttact agtggaacat gatcaaacct tcctggataa agtatctact gagattattt
     7381 ctcttgagag aatctaaccc ttgtaatctc aagaacaaca aggtatggtt aaggggaact
     7441 ttgccaacga aggagagaat cacatgcttt atgtaacgag acacggagaa acaacttgga
     7501 acgcacaagg attagtttgc ggacgggcag atgtgccgct gactgaaaaa ggacagatgc
     7561 aggcacagaa actagcagaa aaggtagtag atttgcctgt tccaatcacg aaaatcatcc
     7621 attcccctct tcaacgagca agagatacag cacaagcagt tgctgatcgt ctcagcttgc
     7681 cgctgaccgt tgatgaacga ttggtagaaa tggattttgg ggattatgat ggactgccaa
     7741 gcaaagatga gaactttcaa aaagcacgtt tagcgttcgc tgtacgattc ccaaatgggg
     7801 agtcagtctt agatgtgtat gcacggatcg ttcctttatt gaaagaatgc atcgaagacg
     7861 aagaaaatgt ctatctgtta gtttgccata atgccttgat aagagtgatc aatgcttatt
     7921 ttcatccgat gcctaatgag gggttcttta cattcatggt agataataca gaattggttt
     7981 cttatgagta attatgtttt tgtgttattt aaataaaata tttcaaggca ctgcttttgc
     8041 ttagcagtgc cttttttagg ttatgacaat tcttttgata atataaactc aacctttaga
     8101 aatgaaattt aattatttta ataaaagtat tgaaattttg tttctttaga tatatactct
     8161 agtcatagaa atgaagacgg atacagaaaa agagggataa tatgtttggc ttttcaatat
     8221 ttatgaacga ttctttgtca gaagagaaga aacagtatat ccgccaaatg gcatccaatg
     8281 gctttgtcgg tattttcact tccatgcata taccagaaga tgatgtttcg gcatatcaaa
     8341 agcgattgat cgaactagga agcgaagcga aaaagaataa actagaattg atggtcgata
     8401 tttcaggaga ggcattggaa cgagcgggtt tttcattaga agatctaacg cctttgaaag
     8461 caattggtgt aacaggttta agaatggatt atcatatttc caatcagcag attgccgact
     8521 ggtcacatca attgaaaatc agtttgaatg ctagcacgat cacgcctaaa gatatcgatg
     8581 aattgaaaga agcagaagct gatttctcac agattgaagc ttggcataat tattatccac
     8641 gtcccgaaac agggctggac aaagaatggt atcagaaaaa aaatcaatgg ctcaaaattc
     8701 aaggtctcct tgtccaaggt tttgtaccag gagatacaga gttgagaggc ccactatatc
     8761 aaggattgcc aactttggaa gaacatcgag ggatccatcc tcttgcaggc gctctagatc
     8821 tattagcaag taacacggat attgtttaca tcggagatgc aggtctgtca gaaaacgttc
     8881 aggagcaatt tgcttctttc caaaaagaac agacagtctt gctccatacg gaacctgtag
     8941 atgaagaatt ttacgaatat atattaggga agcatacgaa tcggcaagac gatgcaagag
     9001 atgtcatacg aagcgcagat gcacgttttc gagagattcc gcctatccca gcaagaaata
     9061 cagctacgcg tatgaaaggg tctattactt tagataacga aaagtatttg cgctatatgg
     9121 gtgagatcca attaaccaaa tatgatttgc cagcggatga aaaagtgaat gtagtagcta
     9181 aagttatcaa agaagagcta ccattgatca accaaatcaa agctggtatg aactatcaat
     9241 ttataagaaa agaaggaaga taaaattgag caaaatcaat ttagagaacc taacaacgga
     9301 acgcagaaac caagaaactt ttggattaga tgagatgagt atttctcaag ccgttcaact
     9361 aatgaacaaa gaagatcaga aagtggccgc tgcggttgaa aaagaactga caagtatcga
     9421 accagtgatt gctaacacga ttgagtcctt taaaaaaggt ggacgtctga tttatatggg
     9481 agccggaaca agtggaagac taggtgtgtt agatgctgct gaatgcgtac cgacattcgg
     9541 tgtagaaccg gaaatggtca taggtctaat tgctggtgga gaagaagcaa tgactgtagc
     9601 tgtcgaaggg gccgaagatt cttatgagct agggcaagaa gatctaatca agctgaattt
     9661 gacaaaaaat gatatagtta ttggtatcgc agctagcggt cgtacaccat atgtgatcgg
     9721 tggattagat tacgcaaaat cgatcggtgc tgtcacagga acgatttctt gcaataaaca
     9781 agccgaaatc agtaaacacg cggatttccc aatcgaagtc gatgcaggtc cagaattttt
     9841 gacaggctct actcgattga agtcaggaac agcacaaaaa cttatcttga atatgatttc
     9901 tactatcagt atgattggta taggtaaagt attcaataac ttgatggtcg atgtcaaacc
     9961 aacaaatgaa aaactaatcg aacgctcaaa acgaatcatc atgcaagcga cagaagctga
    10021 ttacgaaaca gctgaaaagt actttgaaga agcagatcaa aatgttaagc tggctatcgt
    10081 catgattttg acaaatagtg ataaagagga agctcaagca aaattagctg aagcaaacgg
    10141 atttgtaaaa gggaccttat gagggggaaa agaccatggc aaaaaacgaa ctgactttgg
    10201 aagaactggc aaaacaaatt tataaagggg caggcggcat gggcaatgta gaaagcattg
    10261 tccactgcat gactcgtgtg cgtatgaaga tcatcaatga tgatcttgta aatgtctctg
    10321 aattaaaagc gattccagga gtgcttggtg tagtagaaga tgaacagctt caagtcatca
    10381 tcggacctgg gaaagtgaac aaagtagcac agcaaatggt tgatttggca ggcgtgaaat
    10441 taggagaaaa actttcttct gtaagtgcag ctacagcaaa ttcatcagca tctggaaaag
    10501 accgtgtaaa cgaacgggca caagaaatga aagcggcaca aaaatcgaaa caaaaaccat
    10561 ctaaaatcaa atcggtatta aaagacattt ctaatatctt tgtgccaatg attcctgcat
    10621 ttgtcggtac tgggatcgtg gcagggattg ccgcagtttt agcaaactta gtcacagccg
    10681 gaacacttga tgcagcaaca tggcaacaat atatcgatgt gatgaacatc ttgaaaaacg
    10741 ggatgtttag ctacctagtt atctatacag gtatcaatgc tgcacaagtt tttggtgcaa
    10801 caccaactct tggtggagtt atcggggccg ttgtgatgct gacagggatg aatccggaag
    10861 caccactgaa aaacttattt actggtgaag ctcttgcagc tggacaaggt gggatcctag
    10921 gtgtcatctt cgctgtttgg ctattgtcaa tcgttgagaa aaaactgcat aaagtagtac
    10981 ctgatgcggt agatatcatc gttacaccaa ctctttcatt gattgccatc ggtctgattg
    11041 aaattttctt catcatgcct ttagcaggtt tcatttctga tggcatggtc ggtgggatca
    11101 actgggtact tggcgttggt ggagcatttg ccggcttcgt tctaggcaca ttattcttgc
    11161 cgatggttat gttcggactg catcaaattt tgactccaat ccatgtgcaa atgattgatg
    11221 aaactggtcg tacgctattg cttccaattc ttgcgatggc tggtgcagga caagtgggtg
    11281 cagcattggc attatggatt cgctgcaaaa aagataaaga attaacagaa atgatcaaag
    11341 gagctttacc agtcgggatc ctaggaatcg gcgaaccatt gatttacgga gtaacattac
    11401 ctctaggacg cccatttatt actgcttgta tcggtggagg tatcggcggg gcagtgatcg
    11461 gaatgatcgg aaatgtcggg gctatcgcta ttggaccttc aggagccgct ttgatcccat
    11521 tgatctctga cggtaaatgg ttaggctaca tccttggatt attggcagct tatgctggtg
    11581 gcttcgttgc tacattcttc ttcggtattc ctaaagaccg tttagaaaaa gaagaattag
    11641 cgactgaaac agccacagta aatgaagtgc ctgaaaaagt agtacctcaa acttcagctg
    11701 aaagtgtgac tatcctctca tcagttgctg acggaacagt tgtttcttta gataaagcaa
    11761 gtgatccagt ttttgcacaa aagatgatgg gtgaaggcta ctttgtagaa ccagaaaacg
    11821 gacatatcta ttctccagtt actggggtag tcagctctgt cttcccaacg aaacacgcta
    11881 ttgggatcac aacgccaaat ggtttagaaa tcttgcttca tatgggaatc aacacagttg
    11941 acttaggcgg tacgccattt gatgtgaaag taacagaagg gcagcaagtg acacctgata
    12001 cgcttgtagc agaagctgac ttagaagcga tcaaagcagc aggcaaagaa acatccatga
    12061 tcgtcttggt aaccaatatg gatcgtgtaa aaaactttgt cttggaaaaa acaggtaaag
    12121 caaaagcaaa agcacctgtg atggatgtca aagcttaata tgatagaaac aatagaaacg
    12181 aaagaagaaa ctgaaatcta tttttcagct tcttcttttt tattatttat tgttttctgc
    12241 taaaatctga taaattcgtg tcacatcaga tggtgttccc cgtaattcat aatctgccaa
    12301 gaaaggaaag ccaaatgttt gtgcatattg tttggctgtt agacaatact gattattgaa
    12361 gtttttattt ccgctaccga ctacaccaag acaaagttta tgattgtctt catgttccag
    12421 atattcacgc atcgtttcgg tcaagatttc tgtatcaccg ttatctaaac catttccgcc
    12481 gtctaaataa gtaggaacga aagtaaaaaa tggttctgtt tctttcgtaa aatcactatt
    12541 ttcatggatt tcttttaaag taacttcagg attgacagga tcttctgcat gcattttttc
    12601 agcatattct gctagatgtt tggcaaaggc acgcgtattt cctgaaatcg atatatataa
    12661 aatgttcatg gatcatcctc caattctttc cttttagtat agcatctttt ttaagttttt
    12721 tggtggtgta atttggaaag ggactaggcg ctttgcttgt ataatgagaa aaaagccggt
    12781 agaattatat ttctattaaa gtttttatta attaagtaaa aataaaaaag gtttgttata
    12841 ctttttgata aaagcggttt tattttggag gatgcttaca tggatacaga gcaacagaaa
    12901 aaaggaattg gtttaattcc acttgctgcc ttagtaattg gttcagcgat tggaggtggc
    12961 gtatttggta ttatgacgga catctccgga tcggctggcg gcccagctat tttcagttgg
    13021 gtactcgtag gaacagcaat gttgatgctc tccttgtcga tcaataatat caataaaaaa
    13081 cgtccagatt taaaaggcgg gatctttagt tacgcagaag aaggttttgg ccgtttcgct
    13141 ggttttatca gcggttgggg ttactggctc acatgctggt taggcaacgt agcttttgca
    13201 acattgttga tgagcgcatt aggatatttc ttcccagtat ttgaaggtgg gcaaaatctg
    13261 gcatcgatcg tgatgagtac agtcttttta tggggatatg catggctagt gaatcgggga
    13321 gtcgaaaatg ctagtttcgt caatgctatc gtcacattct gtaaattagt gccattattt
    13381 ttatttattg tagtagctat cagcacgttt tcgatccaac aattcattga taacttttct
    13441 agcgacatta tattgaatgc gaatggacag ccgatcccgt tttccagtca agtattgagt
    13501 tgcatcatgg tgatgctttg ggtatttgtt ggtattgaag gagcctctgt cgtaggttca
    13561 cgagcaaaaa aacaatcaga tgttgggaaa gcaacgattc tagggatatt cggcttgatt
    13621 attatttacg tcttggtttc catgcttcca tatgggacaa tgacgatgaa tcagctgcaa
    13681 acgatcaagg cgcagcctgc tatgggctat gtgtttgaaa tgatggttgg taaatgggga
    13741 gcagtcgtga tcaacggcgg tttgatcatt tctttagttg gtgtttggct ctcatggacg
    13801 atcttaccga ttgaaacaat gggaaacatg gctgaagacg gacttttgcc taaagcatgg
    13861 ggaaaactca acaaaaatgg ggcaccaact tatgctatcg tattgacgac gttatgtacg
    13921 aatgtctttt tactttcatt attattcact gacagtgctt ataactttgc ttacacactt
    13981 ggtacagcag ctattttctt cacgtggctt ttcttaggat tgtaccaaat gaaactttct
    14041 tatcagcgga aagaatgggt ccaattttta gtagggcttt tagcaagtgc ctttcaagta
    14101 tgggctatgc tagtcgtagc ctttaatgaa gtaatgcttg ttcttgttct tttcttgcca
    14161 ggcatttatt tttacctcaa agcacgtaag gagcaaaacg agcctgtaca acatatccac
    14221 ttagataaga ttttacttat aggtgtgacg atggtcggag tgattgcaat ggttttattt
    14281 gccactggga tgcttcacgt atagaagtat aaaagaagta taaagagagg ttgtgagcct
    14341 gtcgtttatt caaaaacata ctaggaaagg agctgtgaca caaatgttgt cacagctcct
    14401 ttttcagaat aaacggtgtt taagagacag ccaatcggca ataaggctga acgtctcttt
    14461 cacagcctct tttttgatga gtcatcatac attttttcgc ttaaatacga gatatcctaa
    14521 tgctaagaac aaaacgatgt aagctaaatt accgaatagc atttgattag tagaaagatg
    14581 agtcaattgc ttcatgatct cttcgtttcc aatttggttt tgcagattca acatactgat
    14641 cggattccat ttgatccact cccatttttg gatgagtgca ataaggatac cagatatgat
    14701 tgacgaagca aaataaaaga cgattcctgc tgagatggat gcaccggaac tattgataaa
    14761 gcaagcaatc atcaacacta aacttaaaat cagccataaa ccgatataac tacccaaagt
    14821 ataagtgaac aagctttgga tcagtgtttg accagtagaa accttctccg tgaaggaaat
    14881 cgaagggaaa agaatcagtt tcatcaacac agtgacaata atagctaaaa ggtataaata
    14941 aacagaataa ataactaatg tgatccattt gcttactaat atttctcctc gagaatactt
    15001 tcgataaagg agatttttca atgtaccata ttgtgcttcc atcgaaatga tcgtgcttgc
    15061 agctgcaatc atgataaaga caatccaaga tgtggcacta aaaagctgag cagtcatttc
    15121 aactggatca atgatcgtcg tgtatttttt ggctagaagt gctgttccta tgagcaaaac
    15181 aactaataga acagataaaa cagcagttga ctttttcttg atcaatttaa ataattcttg
    15241 ttttacaagc aatgtcattt ttcttcttcc ccctttactg aatccagaat ttccaataga
    15301 gaagattcca aatcattcgt cagatgctgg acgtctgtca catggatatt ttgtgcagac
    15361 aatagctgga tcacggttcc taataattct tcgttttctt ttaaaagctt gattttatca
    15421 ggatcttcca aagtatatcc agcttctgtc aagatcgttc gagcagctag atcatttgtt
    15481 gtagagataa cgatgaaatc ttgcgctgtt tggttcaatt cagccattgt acattgtttg
    15541 atgatctttc cttgattgat caggatcagc tcatcgacca ttttttcaag ctcgctgagt
    15601 aagtgactgg agatcaagaa agaggtgccc tgagtagcca agtcggtaat gatttttcgc
    15661 acatctcttg ttgcttgtgg atccaaaccg ttcatcggct catctaaaat aacgatagac
    15721 ggatggttca gtaaggcaag agcaattccc aatttttgtt tcattcccaa cgagtaggat
    15781 ttcgcttttt tgtgaatgta cttttccatc ttgagctgat tcacgatagt gtcgatagca
    15841 gatacatcgt tggtttcaga gaataacttc agatgatcat agcctgttaa gaatggatag
    15901 atacccgggt attcgatcaa tgctcctact tgttccaacc ctttatgact agagggagaa
    15961 atctcatttt caccaataca gattgttcca tctgagtaat ggatcagtcc taaaatagct
    16021 ttcatgatcg ttgtttttcc agcgccatta ggacctacta atccaacgat tttgccaggg
    16081 gataagctaa aactgacatc gctgagggct tgtttgtgac caaagttctt ggataattct
    16141 tggaccgaaa gacttttcaa aaatattcac tccttttcta tagatagtac aagcatacac
    16201 ctgatgagtg gagaagtcgc taggtcattg gacttatttc ttattttttc ataaaaaaat
    16261 tgaatattaa ataaaaaggc ttattttttc tgatcagtac ttattccaag tgtctagtgg
    16321 ccgctagtaa tcttgatgcc aatgatactg atgagtagca tccccacaaa gaaccaagtg
    16381 gaaagattca gcttatcatg aaacaagacc acaccaatta tgaccgaacc aactgcgcca
    16441 atccctgtcc agataggata agagagactc atcggcaaac ttttgattgc ctttgacaaa
    16501 aagtaaaaac tagcaatcat gccaatcact gtgtaaaaag aataattgat tttagaaaaa
    16561 ccatcactcc atttcatcat cgttgaccag aatacttcca aaattcctgc tatgattaat
    16621 tccatccatg ccatacttac attcctcctt aactataaaa aaatacacaa aaagaggaaa
    16681 atcatccctt aaaagaccta atggaatgat catcctcttt atcctacccg gtggcagatc
    16741 gtatatcttt ttctgtagta tagcacacct atccagatat cggcaatctc atacttttta
    16801 gtaaagtgta ccaagcactg acggatatat cgttagcgga aaagaagatg aatgctttgc
    16861 aatttcatag aaagaagttg ttatttatta atcatttaaa aaaaacagta actagacctt
    16921 atttctatat attatcgggc aataaattaa aaaaagcttt accttacaat aagtaagata
    16981 atttttgtga taaaaaaata acgaaaaata tttaaaaata gtgtctattt cgtgagaaaa
    17041 caactatatt ttttatgtgt tttgctttat aattaaaaaa atattgtcat tttatggagg
    17101 aaaatatatg gaaaattatc ttagcctttt aggcgtcttg attgttattc tcgggtttgc
    17161 atttaaatta gactcgatat tgatcgtaat ggttgcttta gttgttacag ctttgactgg
    17221 cggtcttggc attcaaggaa tgttagaact tttaggtaca agttttgtaa acaatcgcgg
    17281 gatggcgatt tttatcatca ttatgttggc aacaggaacg cttgaaagaa atggtctgaa
    17341 agaatcagcg gcttccttga tcaagcgatt caagaaagta tctgctggta tgattgtaga
    17401 tatttatggg atctttcgaa tgatctttgc ggcttttaac gtgagttttg gtggagttgc
    17461 tggatttgtt cgtccaatca ttttaccgat ggcattgggg accatcgaat caaaagggtt
    17521 agaagtccat cctaagcatg aagaagaact aaaaggtatg gcttcagcta tggaaaatgt
    17581 ctgctggttc tttggccaag tactattcat cggaggagca ggggcgttgc tagtccaatc
    17641 aacactgaaa gatctaggat atgacgtaac attgggacag cttgctttag tggaagttcc
    17701 agtggctatc acggctttag ttgtggcaag tgtctacttc tatcttaaag aaaagaaatt
    17761 agcgaagaaa tattatccag gaaaggggca ataagatgga cttttttaca aatcctgata
    17821 ttttattagg cgataaatta ctggagatcc tttatatcgt gatgggactc gtattgattt
    17881 acactggagt aagaaattta acagataaaa ccaatcctca tcgttatggg tcagcctttt
    17941 tctggacggt cttaggggta gttattgcag gaggaagatg gcttccggca atcgtgaacg
    18001 gtggcttgat ctttgcgatg accataccag caattgctaa gaaagtcagc aaaggagaaa
    18061 gccggcttcc atcaaaagaa tatatggaaa aaatgtcaga caaactagga atgaaaattt
    18121 ttattccagc tttgagtatc ggtgtctttg cgatcttgtt tgctctattt accaatttag
    18181 gtgctttagt cggcgtgggc gtcggtgttt ttgcagccat gctaatcttg atgttctttt
    18241 ctcgagataa tcgaccaagt acatttttag atgatgcagc agatatgctg ggcacagtag
    18301 ggccgttaag catgttgcca atgcttttag cttctctagg tgcggtattt acaagcgctg
    18361 gagttgggac agtgatttcc aatgcagtag gtacgatcgt tccagaagga aatgtgaaca
    18421 tcggcatcat catttacgct cttggcatgg tgatatttac ggtaatcatg gggaatgcat
    18481 ttgcggccat caccgtgatg acggttggga tcggtgcacc attcgtattt agtcatggag
    18541 cgaatccagc gttaatagga atggttgcat tgacttgcgg tttttgtggg accctgctga
    18601 caccgatggc tgctaacttc aatatcgtgc ctgtagcgat gctggagatg aaagacaaat
    18661 acggagtgat caaaaaccag ttgtttattg cgttatttat gctagttttc caaattgctt
    18721 atatgattct atttaaataa tagaagagag gggttgtgac agaataattg tcgcaacctc
    18781 ttctaacatt gtagtggaac actatttttt tataagaata tattaagttt gatctgttat
    18841 gttatttaaa ctattgtttc ctttatttac gctgttcaag gaaaatggta tgataaaaga
    18901 taaccatatg ttaaatcaat cggacggagg aacaacagat gaaagtacta gtaacaggtt
    18961 ttgatccatt tggtggggac aaagtgaatc cagcctatga agcagtaaaa aaaatgccag
    19021 atgaaatcag cggtgctgaa atcatcaaag tggaagtacc gaccgtattc gaaaaaagca
    19081 gtcaagtagt caaagaagcc atccaacagc accaaccaga tgtcgtgatc tgtgtcggac
    19141 aagcaggtgg gcggtcagca gtctcgttcg aacgtgtcgc aatcaatcta gcagaagcaa
    19201 gaatccctga taatgaagga aatcagccat tcgatacggc tttagaagaa aacggtccag
    19261 ccgcttactt tacctcattg ccaatcaaag caatgacaaa aaatgtacaa gatcatggtc
    19321 taccagcgta catctcttat acagcaggaa catttgtctg caatgatatc atgtatcgtt
    19381 tgcttcattt gatcgaaaca caattcccgg caattcgagg tgggttcatc cacgtgccat
    19441 tctcacccga tcaagtgatc gatcgtccag tgggtacgcc ttctatgtct ttagaagaca
    19501 ttgcttcttc tttgacttat gcagttgaag cagcagtaga aaataaagaa gatatttccg
    19561 gaaatgccgg aacaactcac taatttagca agaaacactg gctggttgct aacgttatgt
    19621 tagtagccag ctttttgtaa ttagaaagga aagaaacagc cgtggaagaa tggcaatccg
    19681 tctttgaaga atggtttcca aaagaaatca gcaaaagcta tcccatcaaa atttctaaac
    19741 aatacacaag cagtcaacgt tgggagatct atgcaaaatt aacgaaaaaa cagcgggaac
    19801 tagtcgataa gcaccgccga tatctaatca gctctcgttt tatggaagaa cattatttag
    19861 ctgcaacaga ttgggtgttt tctgacttca agatcaatcc gttttttcga acaaaacgaa
    19921 gccagcaaaa attgtattgt gagtgtggta gagaattaaa agtgcaatac atcgttaaat
    19981 cgccaaaaac cggaaagatc ctaaaactag gcatcaacca ctttgccgat cacctgcatg
    20041 tctctccgac agtggcagct tcgatccatc agggaatgac aaaagttgat ctggccttag
    20101 acgaattatt atggcttaag cagaagaata tcgattttcc tgaaggacta tggcaaaaat
    20161 actgttttgt cttgtaccaa aatcgtcgga tgaaacagcc atatttaccg gatataaaat
    20221 tagctcagcg gctcgcagaa tttcgccaag tagaaatgcc gatttacata gcggattatc
    20281 aagcattgga aaatgaaatc aagaaaataa gtgaacacat caatgggcag tcaaaaaagc
    20341 gacagataaa aaaagaacta tttgacgact ttgcagaaga attagtaaag gatgtagaag
    20401 aattcttgat caactatcgc gcatttttac gtaaagattg gcaatccatc gtatatgaag
    20461 aagtgccagt acatcctaat gcttattttg aaacatttat ttccgtgttg agaaagacaa
    20521 aacgtcaacg aacaccagaa gtcactgctc agatggaata ttttgcgaaa aaccaacgat
    20581 tcatccaacc aaaaatctat ctatttattt ggaagcaata ttgtcgctat ggttttacag
    20641 aagggttctt cgacagcatt cctcggatag tcagaaatgg ttttttaaaa gtattgcgta
    20701 aagaacgaga agctatacaa tctgctgata agaaagaccg tacagtctca aaagaaaaat
    20761 ggcaactagt agtgaaagat atccaatctg gaaatgtgca agagacaatc gacaaatgga
    20821 aaggaaaaca ttatcgtttt actgaagctc agaaacaagc gttggaatat tatcagaagt
    20881 tagaagaatc actgcgtttc aatgatgagg caagaaagta tctgaaggaa ttactataaa
    20941 aaatagaggc tgggacagaa gcgtttaact ccaagaaata agaa
//
LOCUS       DADVXM010000218        20862 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.guided.045, whole genome shotgun sequence.
ACCESSION   DADVXM010000218 DADVXM010000000
VERSION     DADVXM010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.guided.045"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            267..1304
                     /locus_tag="KB927_002801"
     CDS             267..1304
                     /locus_tag="KB927_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6841637.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(1393..1716)
                     /locus_tag="KB927_002802"
     CDS             complement(1393..1716)
                     /locus_tag="KB927_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBB6841638.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(1703..2410)
                     /locus_tag="KB927_002803"
     CDS             complement(1703..2410)
                     /locus_tag="KB927_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBB6841639.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            2496..2837
                     /locus_tag="KB927_002804"
     CDS             2496..2837
                     /locus_tag="KB927_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HBB6841640.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(3008..3856)
                     /locus_tag="KB927_002805"
     CDS             complement(3008..3856)
                     /locus_tag="KB927_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841641.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            4454..5317
                     /locus_tag="KB927_002806"
     CDS             4454..5317
                     /locus_tag="KB927_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6841642.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            5417..5899
                     /locus_tag="KB927_002807"
     CDS             5417..5899
                     /locus_tag="KB927_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBB6841643.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(6162..6629)
                     /locus_tag="KB927_002808"
     CDS             complement(6162..6629)
                     /locus_tag="KB927_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBB6841644.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            6752..7603
                     /locus_tag="KB927_002809"
     CDS             6752..7603
                     /locus_tag="KB927_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6841645.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(7854..9812)
                     /locus_tag="KB927_002810"
     CDS             complement(7854..9812)
                     /locus_tag="KB927_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6841646.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(9809..10681)
                     /locus_tag="KB927_002811"
     CDS             complement(9809..10681)
                     /locus_tag="KB927_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6841647.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(11023..11895)
                     /locus_tag="KB927_002812"
     CDS             complement(11023..11895)
                     /locus_tag="KB927_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6841648.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            12023..12592
                     /locus_tag="KB927_002813"
     CDS             12023..12592
                     /locus_tag="KB927_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBB6841649.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12659..13396
                     /locus_tag="KB927_002814"
     CDS             12659..13396
                     /locus_tag="KB927_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6841650.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            13627..14895
                     /locus_tag="KB927_002815"
     CDS             13627..14895
                     /locus_tag="KB927_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBB6841651.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            15382..15846
                     /locus_tag="KB927_002816"
     CDS             15382..15846
                     /locus_tag="KB927_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6841652.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            15830..16459
                     /locus_tag="KB927_002817"
     CDS             15830..16459
                     /locus_tag="KB927_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6841653.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            16813..18291
                     /gene="msr(C)"
                     /locus_tag="KB927_002818"
     CDS             16813..18291
                     /gene="msr(C)"
                     /locus_tag="KB927_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBB6841654.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            18338..18784
                     /locus_tag="KB927_002819"
     CDS             18338..18784
                     /locus_tag="KB927_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBB6841655.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(18983..19498)
                     /locus_tag="KB927_002820"
     CDS             complement(18983..19498)
                     /locus_tag="KB927_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6841656.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            19615..20816
                     /locus_tag="KB927_002821"
                     /pseudo
     CDS             19615..20816
                     /locus_tag="KB927_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         6631 a         3703 c         4315 g         6213 t
ORIGIN      
        1 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga atattttgac ttgtgaccga
       61 agagttggta ggagaacacc gtttataaga ggttgtgaca aaagtcttgt cgcaacctct
      121 tttttaacca aaaaagtgca aatagtttac tttaagtaag agaataatta tgatgaataa
      181 aaaaggtgga acaaatagca tactatatat attgaaatga acactgtatg gatgctccaa
      241 cttgatgaag ctaaggagga attcgtatgt cagaaaagga attaatgaag gtagtcggtt
      301 tttatgaagg gttgccgatc gatgatccaa aaagctttat tgatgaaaaa gaacagatac
      361 ctgtacccag ttcacgggat cttctggtaa aagtcaacgc agtatctgtt aatcctgtcg
      421 atacgaaact tcgccaagat aacgggataa gaaatgcttt acgtatctta ggttttgatg
      481 gagtcgggaa agttgttgct gtaggtgacg aagtgcaaaa attttctgtc ggcgatcgcg
      541 ttttttacgc aggtacaaca acaagagcag gaagcaatca agaataccaa ctagttgacg
      601 aacgtattgt cgctcttgca ccaaaaaatc tttcagatga agaagctgca gccttgccgt
      661 tgacctcatt gaccgcttat gaattgttat ttgaaaaatt tggtctaact ccagaagaaa
      721 atgccaatcg cgggaaaaaa atcttagtga tcaacggatc cgggggcgtc ggttcgattt
      781 tgaatcaact agcgcattgg gctggcctag aagtctacgc gactgcaagt ccgaagaatt
      841 ttgaatggct gaaaaaaaca ggtgtagact atccaatcga ttatcatcac gacttaagta
      901 aaagttttcg tgaattagga atcgatcaag tagagtatgt cgctgtatta ttcgatatta
      961 cccgctactt tgatcaaatc aagcaccttg tccgaccatt tggacatgtg ggaacgatcg
     1021 tagggatcaa agagccgtta gatataggtg tttggaaaaa ccaatctatc agcttcgact
     1081 gggagtatat gttcgctaaa acagactata actatgaaat cgaaacgcaa ggagaagctt
     1141 tagcgcacat tgctgcttta gcaaatgaag ggattatccg cagtacattg agcaaggtct
     1201 attcagatgg gatgaatgcg aagaacttga aacaagcaac caaagacgta gaaacaggac
     1261 atatgttagg aaaagtcgtt gttagtggtc cgttcaacgg ataagcaaga atacgccgat
     1321 ttttttctta tttgactttg ataaaaacaa gagcgcatga cagtaatttg ccataagctc
     1381 ttgttttttt atttataata agcgaatcaa cgaaagggaa agaattcctg ccaagacgat
     1441 caccaataag ctttttgaaa gaatagcagc taaaagtgta ggaactgaag ccaaagcatt
     1501 ttcgagattg atctgcggca gatgtccgat attttgggta aatagactgc tgaaccataa
     1561 agcagacata atgacgatcg ggacaaaact taaatactca agcaacggtt gcggtaaatc
     1621 gaattttttc agtaagacaa atggtaggac cctagaaagc caagttgcta aagtacaacc
     1681 taaaatagtc agcaatgtaa actcaaaaga aggcatgttt gatccacacc cccaatccgc
     1741 acccaatcag tgttacaact acaatcacta agttgcttgg gataaaaatc agtccgacat
     1801 ataccagaat caaagtgaga ccaatcagga tcaactgtaa tcgtttagag gtgtttctat
     1861 cagaaatgac ttgaagataa agtaacccga taaacatagc gacgatggcg aaatccaaac
     1921 caaacttttt cggatcagta ataaaattcc ctaaaagtgc gccaacaaga gaagaaccca
     1981 cccacgtcaa ataagaaatc caattagctg tattcatcca acgaaagttt aacttttgtc
     2041 cagtatagtt caatttattc attcccagtg cgaaactttc atctgtcagc aatgtgccaa
     2101 tcagcagatt ttgaagcagc cgatttttct tgaaataagg agcaatcgtc atactcatca
     2161 gaatcattcg ggaattgact agaaaggtcg agaaaacgat ggaaagcaat gggctgtgac
     2221 tagcaagcat gctgactgtg ataaattggg cagaaccagc atagaccagc agggacatca
     2281 acgtgacgac tagtggatga aatccggcag ctttcccaac gataccaaat gcaagtccaa
     2341 taccgatata accgaaaacg gtaggtaacg tgtctttgat cgcagttttt atatctaact
     2401 tttcatccaa taacaaaact cctttagcac gacataaatt ttcataattg tcgttaaact
     2461 tgtgaatatt ctaaattttt aatgagcatt tgtcaatggt gggattgaaa cgtaaagaac
     2521 tagcgggtcg cagatttaca cgtattgttt cggtgggagg aggcgcgaaa aatcttgcat
     2581 ggctacaaat ccaagctgat attttcgatg caacggtcta ttgtttaagt atggaggaag
     2641 gacctgcatt aggcgcaaca atgattgctg cactagggtt agggtggttc gacacacctg
     2701 aaagttgttg tcagaatttt atccaatata cagatgcagc ggaacctctc ttacaaaatg
     2761 tagaaaagta tcataaaatc tatcaacaat gccggaaaat ctatccagca acgaaggaaa
     2821 tttgtcatga cttataaaac aaaacgcgta cctaatagtc aaatgactaa tattgggtac
     2881 gcgttaagtc ttctttactt catcctttgc atgattcgtg tttttaaagc aaggtctgct
     2941 gtatttcttg tggatttagg atggttgtta tcgtttactt gctatttttc attgaaatcg
     3001 tctttcttta ccgtttcttt agttttttat ctattttttt cttttggtta gaaaattctt
     3061 tttcccgaaa gtcttctttc aggattttta tagagtagcg ttttgaataa gaggcgtcag
     3121 tatgatcgac ttggcagacg aaccaagaga acatttgcct tttttctgca tgaggtgctt
     3181 ctgctaataa ttctttccat aaataataac agtcctctat cagaagaagg gttcgttcat
     3241 cctcaggctc ccaatagaat gtttcgagag tagcaatcac ttcattgatc aattcgaatg
     3301 cgggaagata ggcattttgc tgaataagcg attcaactgc ttcttggatg aactttcgca
     3361 tctccatgat gaacttcgct gttttcctgt ttttgttttt cttgataata tgatcgtatt
     3421 tatggatgat agttgttaat ttatctgaat aatttattgc atgaaatggc atcttaactt
     3481 tgaagcgttc gataaagtgc ggatgttcta taagaatctc tgttaaaagc tcccgtacaa
     3541 gagaggaact agcggaggaa acaagggacg agagttcgga aagtgagtag ttggattttt
     3601 ttattggacg ttcttcgtaa gcgaataaga cagcagccat gtgtttgcat ttttttcctt
     3661 ctatggcata tagacaatca caagtcatgt tggtcttttc atcccaagtg atcactacct
     3721 tataatcttc cgtgccagaa actgttgcgg acaagtactt gcttgtatag ttcaaatgac
     3781 ggacaaaacc gtgcagatga tagctgtaac cgcgttccaa aacgttttca ggaaaatact
     3841 caagccaatt attcatctag ttctcctttc atgaaacact tatttatatt tagtataaag
     3901 aaacgtttaa gaaaaaagta gctgatttta catatttgat aatcactttt gctcgaattg
     3961 tcaaaaattc attctccttt tcttttctta gagaatgtga gaaaaagtaa aagaatagcg
     4021 tgttttaaag atggaacttt ttttgttttt tatttatctg acaaaaatga agtgattttg
     4081 ttagaaataa ataattgttc caattgataa aagaggtatg atgtatcgca aagaaaaatc
     4141 caagcagcgt tctgatcagc agtttgaaca acaatttgct ttgtacagta ggtagtaagc
     4201 ggattaacta agggaataaa agatattttt accgctttgt ttacttagaa tctgtcttcc
     4261 ccaaaattta tttttctaaa ggtaaaacat agataggcag ataataccaa ttatccgtta
     4321 cgaaacgctg cttgagaatt ttctttagat ccatacaaca ttttctacat ctgactaaat
     4381 tggttcctga ttcatcaagt aattgacttt ctttgataat atgataaaaa ggcaatcaag
     4441 gaggaagata aatatgctta aagatctgaa ccaattgatc gattacatcg aagaacattt
     4501 gacagaagga ctttcctata aaataatagc cgaaaataca ggaatctctg aatatcaatt
     4561 aaaacgcatc tttacgttta ttgcagggat gtcgctaatg gactatatca aaaaccgtag
     4621 attggctttg gctaatcgcg atcttctaga tggatcaaga gtgacagaaa cggcgtttag
     4681 atatggatat gaaacagtcg aaggtttttc aagagctttt cgtgattggt caggatatct
     4741 gccttcagaa atcagtagat acggcataca aaaatctttt ccacgcttga cattttttat
     4801 tgatgtcaga ggaggaaaat cgatggaatt tcgtatcgaa aagaaagaac agttttatgt
     4861 ggcaggtgtg gcgaaaaaag ttcctgtcaa atttgaagga gtcaatcaag aaatacaaaa
     4921 gttagcgcag acgatcacgg agactcaaag ggaagagatg cataagttag gagatttata
     4981 tccaaatcaa gtaatcaacg tttcttatgg atttgatgga gaccgcttgg aagaaaaggg
     5041 cagtttgatg cacatgattg gctttgctac gacaaaagaa aatccgtacg ctgatttaga
     5101 aatgcttgct atagaagaac acacttgggc catttttcct aataaagggc catttcccca
     5161 aactttacaa gatacttggg ggaaaatcta tgcagaatgg cttccttctt cagattatgg
     5221 gttagtcgaa gctcccgaga tctcttttac aaaatgggga gaggatttca gtaatgttta
     5281 cagtgagatt tggattgcag tgaaagcaaa aaaatagtta aaaaataaaa atatccctag
     5341 aaaaaagagc gtaatcgtgt catttccctt taattttatg taagatgaac ttaatataat
     5401 agaaagggtg ggagaaatgg caaagtatag gatcgaagaa aaaccagatt ttacggtgac
     5461 gggtattggt gtggaattga agagtagcaa tacggatttt gtcggtttgg ctgcagagaa
     5521 acaagcattt gagcaaaaag ttatcggtaa tggaacaata gatgcattga aacaagctgc
     5581 tgaaaatcat tatttcttta cagtcaacga accctataac gggaaaatga tgtactatgt
     5641 cggtgttcaa acgagtcagg atgttccaaa cactacgcga atcatcccat tcccaaaagg
     5701 aacgtatctt gttgtaagcg ctttagcaga atcgcctgaa gaattaagaa atgatttgac
     5761 gaatacggcc tttgggcatg ttttaagaga agtagaagat tacgcctatg ttgggggtcc
     5821 aaatgctgta gtcgaaatgg gagttaccaa cgggaaatat atgggagaaa tctggatacc
     5881 ggtagtcaat aaaccatgat aatatagagg tcgtgaaagt agcgctttga cctgagcatt
     5941 agagaggaaa aatgggaaat agctttccat attttgcatt tttcagaact aatgccgagg
     6001 gtcagctact tgaacaccgt ttatcaagac gtcatgactt cagcgctttg acctgagcat
     6061 tagagaggaa aaaggggcat gacaaggctt ttgtcccccg gagaataaaa gaatttatgt
     6121 agacgattcc gatcagaaaa atgcaggcac agtagagaga attataaaaa tctctctacg
     6181 aggcctgtgt tttctggtct tttttctttt tccaaaacgg ctattttatg tatcagacta
     6241 tcaagtgtga tcttagccat ttcttcttct gcctttttct gcagccgagc gtagctttct
     6301 tctaaagctt cttggatatt cgcaccaacg acgcaatttg gatttgtttt tggatcgact
     6361 tggataagct gtgtattacc ttcgatgctg cgatagacat ctagtaaaga aatctgatct
     6421 ggacttttgg caagggaagg ctgcggtttt ccggtttttg taaagatcaa accggatttt
     6481 ttgagctgac tcatgatttt acgtacattt gctgcatttg tttcgatact actggcaatc
     6541 atctcactag aaagtgatcg ggtatcttga aacatttcaa tataggcaag tacatggatt
     6601 gcatcactaa attgcagaga atacttcatc agttgtcatc ctttcatttt ttttgcttga
     6661 cttatcttac cacactcttt atgataaagg tgtaatttat aaatgtacag ctgtaaatct
     6721 taacaaataa aaagaatagg gagtggcaaa tatgcattat ttagtaacag gagcaactgg
     6781 aggttttggt ggttatgcgc tggaattctt aaaaaagatg gttccacaaa atgaaatcta
     6841 tgtactagta cgtagtgaag aaaaaggaga agcactgaaa gaagctggat ttaatatacg
     6901 tattggtgat tatgatgatt tagactcaat gaaagaagcg ttgaaaggaa tagatcgatt
     6961 gctttttgtc tctggcgttc caggaaatcg tcaagccgaa cataagaatg tagtgaaggc
     7021 agcacaagca gctggggtat cttatatcgc ttatacaagt tttgcagatg ccgatcactc
     7081 gatcagtgta ttagcgccag atcaccaatt cactgaaaaa atgattaagg attcaggtat
     7141 ttcccataca tttttacgga ataattggta tgtagagaat gaattaccta tcattgggca
     7201 ggctttaaaa actggtcaat tcgtttatgc tgcaggaaat ggaaaaacag gttgggcatt
     7261 gaaacgtgaa tatgcagaag ctgcagcaaa agtactagta gaaagtgact ctccagaaat
     7321 cttagaatta tccggcaatc taactgacta tgaagaatta gccaaggcat tagagcgtgc
     7381 gacaggtaaa gagttagaaa ttattgaagc aagtgatgca gcgtttgtcg aaaatctaaa
     7441 agaagccgga ttccctcaag aagcagctga catgttttta gcgatccaac atgatattaa
     7501 aaaggatcag ttagctattt cctctgatga tttagaaaaa gtattgggaa aaccattaac
     7561 ttctcttgaa gcagcattaa aagaaatatt ggatcaggaa taatgtataa agaggttgtg
     7621 aaaaagccga ttagttttga gtatgaagaa aaattttgtg aaaaagctgt tctgcatcaa
     7681 gtaataagaa gagtcaaata aaaaatagct cttcatatgt ttcgtttagc tggacttatt
     7741 accgcggagt tggcaggaga acgccgtttt tattcggaaa aaggagctga gacaagattt
     7801 ttgtctcagc tcctgtttgt ttatcgataa aaaagtctgg ggaagacgat ggctcaggct
     7861 ttgttggaaa cagagccgat tttatcattt gcttttacat cacgtgcggg ttcgatttct
     7921 aagctttgga ctttgtcgcc atttgtgaat acaacgacca tatccgtgtt tttgcctgca
     7981 gattgaatag cggcaagatc aactaaagca atcaattgac ctcttgcgac tttttgacct
     8041 tcttctacat ataaagtgaa tggttcgcct tttaagtcaa cagtgttgat gcccatatga
     8101 agcaagactt cgataccagc atctgtttgg attccgacag catgtttcgt tgggaaaatg
     8161 tttgtgatcg taccagcgat tggagagaag atttctccat tttctggtaa tacagcatag
     8221 ccgtcaccca tcattttttc cgcgaataca tcatctgaaa cttcagtgat tggaatcagt
     8281 ttcccatttg cgatagcgta aatatcttgt tcgatcgttt caccggcaaa tgtttctgtt
     8341 ttaaccacgg tgtttgtttg tgcaggtcgt gctgcagcac caccatgtag ttttgccatc
     8401 tcatctgcaa cgaattgtac ttctgtacct acgatgactt gcgcattttt tccgtcgatg
     8461 atcttcatac caggtacgcc agtggctttg attttatttt gatcgatcag gcctgtatct
     8521 ttgacttgca aacgaaggcg tgtagtacag ttatcgatcg aagttacatt gtcggctccg
     8581 cctaatgcag cgtagatttt gcttgcttgt gccgcatatt tattgtctga attagtcgtt
     8641 gcagtatcgt catctgaaag atctgcttcc tcgcggccag gagtcatcag atggaatttt
     8701 ttgatagcaa agttaaagcc aaagtagtaa atcactgctg ttactaatcc ttggacgatc
     8761 aacatcaatg gctgattcgc aatcggattt ttcaaagata ggaagtaatc gacaaatccg
     8821 gcactaaagg caaatcctgc tgtccaatgg aagaatgcac tcactgctaa agaaatccca
     8881 gtgaaaattg catgcaagac atataatggc caagcaacga acataaatga aaattcaagt
     8941 ggttctgtca caccagtaaa gaatgaagca aaagctgctg ctagcatcaa ggaagctgtt
     9001 tttgctttgt tttctggacg tgcatttctg taaatagcat atgctcctgc tggaagcccg
     9061 aacatcatga ttgggaaaaa tccagcttga tacattcctg ttacgccttt tgttccttca
     9121 gaagccaaaa atttaccaat atcattgatt cctgctacgt caaaccagaa cacggagttc
     9181 attgcttgat gcaatcctgt agggatcagt aaacggttga agaagccata aagacctgca
     9241 ccaccccagc ctaaactcaa aatgaattta gcaaaagaaa ctaaagcaga gtaaaccgga
     9301 ggccatacga gcagtagcac tgcactgatc agcaacatga caaaggcagc caagattggc
     9361 actagacgct tgccgctaaa gaaagataaa gccatcggta attttgcttc gtggaaacga
     9421 ttataaagag ctgccgcaat caatccggca ataataccaa taaatacgtt actgatctga
     9481 gcaaaagatg gatcaactga ttctggtttg atattcaata aagtagctac tgaatcagtt
     9541 tttaaaacat ttactggaac ttcaaatgcg accaaacctg ccaaggcagc agcacctgat
     9601 ttgtccactg acatccctag tgctaaccca acggcaaaca gcaaaggtaa ttgacctaaa
     9661 actgcgttac cgccagcttg taaaaaatga gcgacaatgt cgttactata agatgcccac
     9721 cagtttccga tccctactag taaagcagca gcaggtaaga ccgcaactgg aagttgaagg
     9781 gaacgtccca ttcgttgtag atatgctttc aatttttttc ctcctcatga ttgttaacat
     9841 ttgtttgtac gattgcgctt cttaaacgct cgatatggat ggccaagtaa cccagttctt
     9901 ctttcgtgat cgcgagctgg tattctttgg tcagcaacac acggattttt ttagaaatct
     9961 tatagctttc tgggtatttt cgtttgacca tttctacgat ttccgtgtct aaaacagcat
    10021 attgttgcgc atgggttcgt tgtagaagca gtcgtaaatg attcaccagt cttgaataat
    10081 tcagtgaaaa tggttctgaa tggatatctg tttccaattc tgattccact aaatggatga
    10141 tgtcagatac aatcgtcact tcacggatac tgcgatggtt attgttccga ccgcttcgtc
    10201 cgctgtgaat atggattgcg atatatcctg cttcgtcata agtatatgga atcccaagct
    10261 cttttgtcag atactctact gcccattgag caatactgaa ttcatcactg taaagcactt
    10321 cgatttctct taaaagtttg ttgcggatga cgataccgtt attaatgttc tccgcagaaa
    10381 aagcaatgtg gtcggtcaaa gcgatcaata catgttcatt caacttttcc atcaaaacag
    10441 tttccgcatg atcaatgatc gtttctgctg caaataaaaa gcgttcatca atctgattaa
    10501 gtaaattttg caacttgatt tgaccttctg gttccatgac aaatatccgt tcgacatcac
    10561 gatcaaaaat caaatcattt ctttttctgt caaatccaat cccttttcca atagctactt
    10621 tttcctgtcc accgtcatct accaatactg cattttgatt aaagatcttt ttgattttca
    10681 tgcgcgcacc ctttttgaag atttggtttt cacgtttgct agaccagttg attgcggcca
    10741 aacaaaaata gacacgaaaa acctcctagg gaaaccatgt tcctcagaga tttttcatgc
    10801 ctagtatgat ctagtcacat gaaacgaatt attgttaacg taatcaattt tatatagaca
    10861 gttatgtttt gtcaattctt tttttataat tatagtaatt tactggaatt atcagaaata
    10921 aaaggaagaa ataaattaag aaacttatgt tatttaatcg ttggatcttt tgcttatctt
    10981 attcgttgtt aaaaagctga aagcgaagga aaaaaactct acttaactgt atttctccgt
    11041 taggacatct aaaaatttac gagcagcagg agaaagaggc tggtcttttt tccaaatgag
    11101 attcagtgaa gcttgtaatg gcggatcgag tgggatgaat attttttccg tcccataagt
    11161 attgatgatc ccatctagag ctaatgcacc aaaagtcccg ttatcgacca tcaaagaagc
    11221 attgtacaat aagttatatg ttccgacgat cgataactga tctatgctga aacctagcca
    11281 ttcagctagt tgactgtcca ctgacgtttg ccgggaaatg atcaaaggaa cagttttcag
    11341 ttcctgcgga tggatgacgg tttgctttgc taaaggatga tttcgatgta tcaaaagtcc
    11401 ccaacgatct tgggctggca gtcgaaatga ctggtatttt tgtttgtttg tcggttcgat
    11461 tacgagtcca aaatcaagta atccgctatc cagtttgtct atgatatcat ctgcattccc
    11521 gctatataaa tgaaactgga tatcaggatg cgccttgatc aacgaatgaa ggctatcaga
    11581 aatgaaagag attgctttag tttcgcctcc gccaatgtag atttctccag agatgattgc
    11641 gtcatttgtt aaattgttcg ccgttttttc taccaacgac aagatttctt ttccttttga
    11701 ataaagatat cgaccagaat ccgtcaactg tatctctcgg gagccccgag tgaaaagtgt
    11761 cacaccaagt tcttcttcta aatctttcag ttgttttgag agagtaggtt gcgtgatatg
    11821 cagagatttt gctgctcggc tgatattttt ttctctagct actgctaaaa aatacgtcag
    11881 tatacgaata tccatttttt ccctcctgtt tttaaaaaag cataccacta agtatagtta
    11941 aaaggaatag ttaagtatgt tttataagta ttagacatga taagccgtcc gttataaagt
    12001 aaggataaaa ggagggagca aaatgacaag cctcatcgaa aaacaaatcg tcaataaaga
    12061 gattcgagta acggatccgc tctttgaagt gatccatcag atccaagctg aaaacgaaga
    12121 gcctttagca gcgctgaata ctgggtacca tgaaccagca gatatccgca aacggctaga
    12181 aaatatcatt agtgacaaag tagatgatac ggtgactgtt ctgctgcctt tttatacaga
    12241 tttcggcaaa catattagta tagggaaaaa tgtctttatc aatcgtcaag tgatgttcgt
    12301 tgacttaggt ggcatctgtt tagaagattc agtattgatt ggtcctcgtg tcaacctcat
    12361 cacggtgaac catctaaccg atccaaaaga acgaagaggc ttgtcagtaa agccaatcca
    12421 catcaagaaa aatgcttgga tcggagcagg agcaactatt ctgccaggcg taacgattgg
    12481 cgagaatgcc attgttgcag cgaatgcaac tgttacgaaa gatgtcccag acaataccat
    12541 cgttgcagga atccctgcca aaatcgtcaa acctgtcgaa cggattattt gaacagtaag
    12601 atgaaataag agatagtgag tataagcaag agatttttca aaacaggagg agaatagaat
    12661 gaatgattta tcagaaaaag tgattgtcat catgggcgct tcaagcggaa tcggtgaagc
    12721 aacaacgaag ctattagcag aaaaaggggc taaactagtt atagctgcac gccgagaaga
    12781 tcgcctaaaa gcaataaaag aatctttacc agaagctgag ctatatattc aaacagcaga
    12841 tgtaagagat tttgcacaag tccaagcagt tatcgattta gcgatggaaa agttcggtcg
    12901 aatcgatgta ttgtacaata atgcaggaat catgccaacc gctccattag ttgaaggtca
    12961 ccgtgatgaa tggcaaaata tgcttgatat caacatcatg ggtgtgttaa atggaatttc
    13021 cgccgtactt ccaatcatgg aaaaacaaaa atctgggcat atcatttcaa ctgattctgt
    13081 ggcgggacat gttgtttatc ctgattccgc cgtttattgc ggaacaaaat ttgctgtccg
    13141 tgcaatcatg gaaggattac gtcaagagca acggcaaaat aacatcaaat ctacgatcat
    13201 ctctccagga gctgttcaaa ctgaattata tcaaaccatc agcgacaaaa aggctgctct
    13261 tgaacttcat gaagcgcaaa aagaatgggg attgacctcc gaagatatag cttctgctgt
    13321 agcatttgcg atagaaacgc cagaccggat gtctgtcagt aacatgatta tccgtccgac
    13381 gacacaggaa gtataatcca taacggataa tatccaaaga gaattacttg ttaaatagtt
    13441 attcaaacga ccatcaattt aaggcgtgaa tggagaagaa tattcttcat ttacgtcttt
    13501 ttatgtagaa aaagcaaatt tatcaaaaag aaacaaatgt tatttaaata tggacattga
    13561 cttgctttta cttttttagt tacactgtta tttaggaaaa gtttcataat tcaaaggaga
    13621 aaaaagatga aagcaaagaa tttattattt agcgttattc ttttaggaaa tctagcagtt
    13681 gccaacacaa cagtgctagc tgaagaatcg acagaaactg tcgcaactca gacatcgagt
    13741 tcttcagaaa caggaattga aaacgataca gagagtactt tgcagtcagc tactgtctca
    13801 gaaaatacaa tttcaaccga agaaccaaca actgaaacaa cagaacaaac acaaaccgaa
    13861 gacagtacat cagcagaagc tcagaacaat ccagagaatg cagaagaaat cacgaaccaa
    13921 ttgacagatg ggcaaacatt gacacatacc catcaagcag atttgtctga attcgaaaac
    13981 tatactggct atgcttttta tgctcgctca tctgctaatt ctcaacaagc gttcattgat
    14041 agtattgcct caactgcaca aagtttggca agtgccaatg acttatatgc atcagtcatg
    14101 attgctcaag ccatcgttga aagtggctgg gggaacagta ctttggcttc tgcccctaat
    14161 tacaatctat ttgggattaa aggaagctat aatggccaat ctgttacgat gcctacttcg
    14221 gaatatgtga atgggcaatg gattacggtg aatgccgctt ttagaaaata tccttcgtac
    14281 aaagaatcat tgcaagataa cgtaacggta ttgaagacga cttcttttca gccaggcgtt
    14341 tactactatt ccggtgcatg gaaaagcaat acgaactctt acaaagatgc tacggcttgg
    14401 ctaacaggtc gttatgccac tgcgcctaat tatggttcta cattgaacaa tgtaatcgaa
    14461 acctataatc tgacacagta tgatacagca ccaacttcaa cttctccgat gtatcgtctg
    14521 tataaccgtc atacaggaga acatttatat acattgaatg ccggagaaaa aaattatctg
    14581 ccaactgtag gctgggaata tgaagggatt gcttggcaag caccaaacag cggacaacct
    14641 gtctaccgtt tatacaatcc ttacagtgga gaccatcatt acacaatggc acaatctgag
    14701 atcaactctt taacaaaaat cggttggcgt tatgaaggtc taagttttta ttctggtggt
    14761 tccaagccaa tttatcgact atttaatcca aatgaaaaaa ctggtaccca tcactatacc
    14821 ttgagtgcta aggaaagaga ttggctaaca ccgatgggct ggagatatga aggaatagga
    14881 ttttatggtt attaaaaaga ggtagtgaaa aagctgccct gcatcaagta gtaagaacag
    14941 ccaaacaaaa acagattttc atgttttttg tttggttgaa cttattaccg cagatgcaag
    15001 tttttgaaca ccgtttactc aaaaaaggtt gtgacaacat cttgtcataa cttttttatt
    15061 actgtttaag catactgatc caatttctaa tattcgacgg gattcttgca aaaggcgatt
    15121 tcggaaattt ttggcggtgt aaaattttct actgcagaag agctatcttc tatagtttga
    15181 taagaatcaa taatcttggt tttagcgttg tgctttcttt atcatttttt ccgttcattc
    15241 tacaaaaaat ttcttttctc tatacttttc tattgagagc gtttttttta ttacacagct
    15301 gattctttga cttttttctt tttttattct attattgaca agtcaatcgt tgacgagtca
    15361 attattagaa aggaggaaat tatgtcttta gaagagatta gtcacctttt atatcaaatc
    15421 aaattagccg atcaaaaaat cgtccagatc tttgaagaaa atatcggtat aagtcttact
    15481 agatacgaga tcatgatgag actgaaagaa gaaaatccat tgctacaaag cagtttgcaa
    15541 gaaaagttgc agattgatca aggagcagtt actcgtcatc tgaaggtatt ggaagcaaat
    15601 ggctatgttt cgcgtcagag aaatcctcag aacaaccggg aagtgtatgt agcgctaaca
    15661 gaaaaagccc agaagaaaat cgagcattgt gaaatggacc ataaagatac aggttccgtg
    15721 ctatccccgg ctttcagcga tgtagaaatg aaacaatttc taacactttt agataaattg
    15781 aatacccaac tttgcaatat aacaacagaa acgaaagagg ttaataataa tggaacaaaa
    15841 aaatgatttt tcaacaatta tgactggtag aagatccgtt cgcgtatatg atgaaacata
    15901 caaaatccca cacgaagaaa tgctggaaat gatcaaagaa gcgacgactg caccttcttc
    15961 tgtcaatatg caaccatggc gctttgtggt cgctgaaagc gaggaagcaa aagaaatctt
    16021 gcgtcctttg atccgtttca atacgagaca aaatgatact tcttctgcaa tggtcatgat
    16081 ttttggcgat atgcaatgtt acgaatatgg cgaagaaatc tataaccaag cttacgaatc
    16141 agggaagatg ccaaaagaag tcagagatca acaattagct gcgatcattc cttattacaa
    16201 gagtttttca agagaagaaa tgaacgatgt agtcaaagtc gattctagct tagcggctat
    16261 gcaattcatg ttagttgcgc gtgatcatgg ctatgaaaca aatccaattg gtggattcga
    16321 agcagatcag ttggcagagg catttggttt ggataaagac cgttatgttc cagttattat
    16381 tttatcaata ggaaaagcgg tagaagaagg ttacgagtct gttcgtttag caccagaaaa
    16441 gatcactacg ttcgaataaa aggttttcag ttactattca gtagctattg ctttttttga
    16501 atcgtgtgtg gtaacctaat aaaaaaggag gtcggaaaaa tgactgcatc gatgaaatta
    16561 cgtttcgaac ttttgaataa caactaaata aattcaaaag acatgtataa acaacaattt
    16621 catggatgga gtatgtccat tttttcgaac gacagtagaa taggtgaaag ctatgacaga
    16681 tttggtgatt tagtcatagt tatttcgttc agagtaggaa aagatgtgat gcagtttttt
    16741 tgcaaacaga tttttctgct cttttttagt atcgataatt gttgttttac atgaaatagg
    16801 agtgtaaaac atatggaaaa tttagcagta aatataacaa atctacaagt cagctttggc
    16861 aaccagctag aactatctat tgattctctt cgtgtctatc agcaagatcg tatagggatc
    16921 ataggagaaa atggtgtcgg taaatcgact ttgctcaaac taatagccgg tgaacttttt
    16981 cccgatcatg ggaaaatcca aacagagatc accttcaact acctgcctca attaacctat
    17041 ctcgctgaag caaaggacct aaatttggaa ttagccagtc atttccagtt aagactggaa
    17101 gaaacttcag agcggaaatg gagcggaggg gaagaacgaa agatcgagtt gatacgtctt
    17161 ctttcttctt atgaacaagg gatgcttcta gacgagccaa caacccatct agatagaaaa
    17221 agtattgatc gactgattga agagcttcgt tattattatg gtacgctggt ttttgttagt
    17281 catgatcgct attttctaga tgagctagca tcgaaaatct gggaagtaaa agacggagaa
    17341 atccgagagt tttcggggaa ttatagtgcc tatctcactc aaaaggaatt ggagaaaaag
    17401 actcagctac gagaagcaga gtcgatcatg aaagagaaaa aacgattgga aaaatcgatc
    17461 caagaaaaga aaaaacaagc ggaaaagttg gaaaaagtgt ccagtaaaaa gaaaaagcaa
    17521 caaatcagac cggatcggtt gtcttcctct aaacaaaaag acagtgtaca aaaagccatc
    17581 caaaagaatg cgaaaacatt agagagaaga ctccaaaaaa taggagaaac aaccaagccg
    17641 cagcagatga aacaaatccg ttttccagta ccaaaatctc ttgaactcca cagccgctat
    17701 cccatcatgg gacaaaatgt ccaattggaa agaagtggga gaacattact ggtaaatggt
    17761 gattttcagt tttctttagg taaaaaaatc gcgattgtcg gtgaaaatgg ttcaggtaag
    17821 acaaccttat tagaacatat ccgcaaacaa ggagaaggaa tccttctctc tccgaaagta
    17881 agctttcaag tatatcagca aaagggttat caaatgacat ctgaagaatc catcattcgt
    17941 tttgtcatga gacaaacaga gttttcagaa tcgcttgtcc gtagtttgct gaatcactta
    18001 gggtttgctc aggaaacttt gacgaaaccg ttatgtacat taagtggggg agaagcgacc
    18061 cgtctgacga ttgctttgct ttttactaag ccaagtaatg tgttgctgtt agatgaaccg
    18121 actaatttta ttgatatggc aacgatcgaa gctttagaga agctaatgca aatatatccg
    18181 ggaacgattt tgtttacttc tcatgattct tactttgtcg agcgtacggc tgatgaagtt
    18241 tatgaaataa aagggcagaa aataaaaaaa gtacttacga gaaattttta aatgtgctac
    18301 gatgattttc gtgacaaatt taaaggagtg gtacagattg cctacaaata aaaaagaagg
    18361 aataattttt acaacaatga tgtgtttttt gatggtcttg gggatgagcg cgtataattt
    18421 atggctgcat caagatcttc atttatcaag tttgttgatt ggtctagtgc ctggattcgt
    18481 ggtggctttc attttggatg tcttcatcat cggtgtgctg gcgaaaaaaa ttgcctttaa
    18541 actaccagta aatccagaaa gcaaggtcca aatgatctta actatttcat gcttgatggt
    18601 tttaggaatg gtgacatgta tgtctttatt cggtgtgatc atggaacaag gaatacctga
    18661 tcaattattc tctgcttata tgaatgcttg gaaaatgaat gtgattgccg ctttaccgtt
    18721 gcagttgatc atcgttggcc cgctttcaag aagtgtgcta aaagcaattc aaagtaatga
    18781 atgatggaac actgttattt gaaaaaaggc cttggcatgc tttttgtcat agtctcttga
    18841 atgcagttct agaaaaatag tgatccgaac gataggtttt ggcctgtcgt tcggatcgct
    18901 ttttcttttc caactgtatt gctcttttat tgaagataat ttgctcttca atagatattt
    18961 ctagaaaggt tctgtttatc ccttactcaa aaaactgctg catttgttct cttacttgct
    19021 gacaccattg gagttcctgc tgacaaagca taattctgcg ctggatcaca acataacgtc
    19081 caaattcttg tttcttgtct agcgagaggt cattcaattt tttttgattt ttttgcatga
    19141 ttttgttcag ctgttgttct ctagtgaata gcagtccagt agctgttgtt ttatcgagcg
    19201 tcgaaaaagc atagattttt gctagaaatt catctttttg cgtaggagcg ggagtttcct
    19261 ctttgatcca ttcctctaca agagcacgtc cttcatcagt caagtggtag atcttttttt
    19321 gagagtgctc gtctttgtcc aaaacggtca cataaccctg ctggtctaac ttggcaagcg
    19381 ttgtatagat ctgactgtga tgggcttccc aaaaaattgt gatcagctgc ttcaattcat
    19441 acccagaacg tggtttggat aaaagcacgc ataataatat ataggctaaa gtattcataa
    19501 aaatcctacc tctcgtctta ttttctttat tatatcacag taaagtttcc acgttttaca
    19561 tgtgcatatt tacatgtaaa ataaatcatg tatgatgcta atagagagaa agggatggaa
    19621 atattggaga atcaaataga tatacaagaa caaacaaatg aagaaacaaa ggggaaaagt
    19681 tcagcgctag ttgtagcagc tacctgtatg atcgctttta tgggagtggg tctagtagac
    19741 ccaatcttaa aaacgattgc tgcacagtta aacgctacgc cagctgaaac gaccctgtta
    19801 tttactagtt acatgttagt cactggtgtg gtgatgctat ttacaggttt cttatctagt
    19861 cggatcggtt tgaaaaaaca ttgatgacag gattgtttat catcgttgta ttcgctggtc
    19921 ttggcggatt atctgggaat atcggaatgc tgattgggtt acgtgccggc tggggtgtcg
    19981 ggaatgcttt atttgtctct actgctttag caacgatcgt cagtatttta gttggtaaca
    20041 cagaaaaagc aatcatgatg tatgaagcag cacttggctg cggaatggct gttggccctc
    20101 tagtcggtgg ggtcttgggc agtggttcat ggcgttatcc attttttggg gtagcatttt
    20161 tgatgttttg cggttttata gccctagcgg tacttttacc tgaaactgag aaaccaaaga
    20221 gaaaagtagg cctttgggaa ggtgtcaaag cgttaagcaa tcataaactt cgttcagttg
    20281 gactaatcgc attgttatat aatttcggat tctttacttt acttgcgtat gcgccatttt
    20341 tattgattgg ctattctgaa ttagaagtcg gttttgtatt ttttggctgg ggtgtgcttc
    20401 tggctattgc ttcgattttc gttgcaccgg ctcttgagcg gaagtttacg acttatcgga
    20461 caattttagc agcatttgtc ttattcatta tttgtttgct gttattagga gctggaactt
    20521 ctatgccagt ccttgtaccg atcagcattg tgttagcagg atttttccaa ggaattatca
    20581 atacactgtt gacgacgatt gctatggaaa taccaggtct gcaacgaaac gttgcttcgt
    20641 ccagctatag ttttgtccgc tttttcggtg gagctttagc accatttatt gcaggtgtga
    20701 ttggtgaaca tattggtgaa agctatgcgt tttattttgc aggtgccatt gttcttatca
    20761 gtgtatgttg tatcatttat caccgtaatt attttgctac aaatgaagaa gaataagaaa
    20821 tcagaggttg tgaaaaagct gtcctgcatc aagtcataag aa
//
LOCUS       DADVXM010000219        12870 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.guided.070, whole genome shotgun sequence.
ACCESSION   DADVXM010000219 DADVXM010000000
VERSION     DADVXM010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.guided.070"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            29..424
                     /locus_tag="KB927_002822"
     CDS             29..424
                     /locus_tag="KB927_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841657.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            749..1366
                     /locus_tag="KB927_002823"
     CDS             749..1366
                     /locus_tag="KB927_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6841658.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            1407..1706
                     /locus_tag="KB927_002824"
     CDS             1407..1706
                     /locus_tag="KB927_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBB6841659.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            1740..1907
                     /locus_tag="KB927_002825"
     CDS             1740..1907
                     /locus_tag="KB927_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6841660.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(1952..2557)
                     /locus_tag="KB927_002826"
                     /pseudo
     CDS             complement(1952..2557)
                     /locus_tag="KB927_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2698..5664)
                     /locus_tag="KB927_002827"
     CDS             complement(2698..5664)
                     /locus_tag="KB927_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HBB6841661.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            5810..6385
                     /locus_tag="KB927_002828"
     CDS             5810..6385
                     /locus_tag="KB927_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6841662.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            6599..7294
                     /gene="vanR"
                     /locus_tag="KB927_002829"
     CDS             6599..7294
                     /gene="vanR"
                     /locus_tag="KB927_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBB6841663.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            7272..8426
                     /locus_tag="KB927_002830"
     CDS             7272..8426
                     /locus_tag="KB927_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBB6841664.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            8641..9609
                     /locus_tag="KB927_002831"
     CDS             8641..9609
                     /locus_tag="KB927_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBB6841665.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            9602..10633
                     /gene="vanA"
                     /locus_tag="KB927_002832"
     CDS             9602..10633
                     /gene="vanA"
                     /locus_tag="KB927_002832"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBB6841666.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            10639..11247
                     /locus_tag="KB927_002833"
     CDS             10639..11247
                     /locus_tag="KB927_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBB6841667.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            11675..12586
                     /gene="vanY"
                     /locus_tag="KB927_002834"
     CDS             11675..12586
                     /gene="vanY"
                     /locus_tag="KB927_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBB6841668.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYETWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         4112 a         2272 c         2611 g         3875 t
ORIGIN      
        1 aaaataagta tatgaattgt aaaaggacat gatgattatg gaagaaatag aatggaataa
       61 tctgactcaa aataataaaa ataattctgg atgtggaatt atctttatgt ttgttatagt
      121 tttgggaata gtagtacttt taataactgt caagatagta gattactttg cgaatactcc
      181 tgaagaacaa atacagagaa aacttcctga gtttgaaaga gtaccacctt atgatccaag
      241 agataattca tttcaagtaa aaaaattaaa agagtctcca aatgaaatgt ggtttgaagt
      301 tacagttgaa tcaagcgact tcaaagaaaa aaagaaagaa tacaattata ttgtaaaggc
      361 aaaagtatca aaaagattta tttttaaccc taaattagaa atatatagtg ttgtaataga
      421 ataatagtgt taaaaaaatt gtaaaagtta aagaagtcaa attctgatgt gaaaaataaa
      481 atataccatg gaagacataa aagaaaaact ggataactag tttatttaat ggcagaccgt
      541 taaggcctgc catttttatg tattttagcg gaataaatat aatcatgcgg gagtgtaaac
      601 ttactgtttc aaaaagtata ctttttgaca tgccttgatt ttctttgttt atgtatggca
      661 taataaccac ataatacaat ttgaaacgtt tctgatttaa tctgattgtt ttgaaacaat
      721 tttagtgaaa aaagggtaga taaaaacgat gagaaaattt ttttatatcc gggtcagtag
      781 ttatgatcaa tcgatcgaac gacaactgat ttccgcgaag gaattaggaa tccctgaaga
      841 atatatattt gtagaaaaag ccagcggcaa agattttaaa cgccctgaat atcaattaat
      901 gaaacggatg tttcgaaaag gagatttact ctatctacaa tcattagata gactaggcag
      961 aaataaacaa atgattttag aagaatggcg agaattaact aaggaaaagc agattgatat
     1021 ttctgtgtta gacatgcctc tgttagatac tgctagttac aagcaactag atgggttaga
     1081 gacgcttatc tctgacttaa ttctgcaatt actcagctat atggccgaag acgagcggaa
     1141 acgaattaat agccggcaaa gagaaggcgt agaagctgcg aaacaaaagg gtgtaaaatt
     1201 cggcagaaag aaaattgctt tacctcctga atttcctgcg atctattctg actggaaagc
     1261 aggaaagata actgcagtct atgctatgga tcaattgggc atgaaacgaa atacctttta
     1321 tcgacgggtg aaagaatatg aacatacctt gcaccacttt tcttgataga tataacagct
     1381 attagacggg aagggagagt ttgaaaatgg acttaacgaa tcaaagggtc gtttttactg
     1441 gaacgctgca gcaaatgaca cgaacccaag ccatcggttt ggttcactct ttaaacggcc
     1501 attgtcaatc aagtgttact tcaaaaacaa atttcctggt ttgtggtcag tattctaagt
     1561 cgttgtttga tgattctctc tatacaaaaa aggaacaaac cgcgcgggac ttgattgcgt
     1621 taggtcatga gattaccatt ttatcagaag tcgaatttta tgcgttaatt agtcaacagt
     1681 tgaaagaatg gcaacggtat ttataatcgt tagtaaaatt tacaaggagg aaaattttta
     1741 tgaagcgaaa atcttatgat cgttggggca ttgaaataac tagttttaat cgaaatattg
     1801 cttttcacgt ggagtgtgac tgtggggaat tagcaaaaag tgtttatcaa aaaaattact
     1861 tttactgtcc taaatgccat cgccgatacg gggtacatgg aacatagaaa cgaaatagtg
     1921 cggtagaaaa gcgaatgaat gtagtatatt tctacaaatc attcgctttc tttattttat
     1981 aaatagttgg tcgagagatc ccgttttctt ttgcaatctc tgcaactgga atgccttgct
     2041 ttaacatgtc caccacggtt ttaaaaacta agcgtttttg cggatctgtt gagttaatag
     2101 aatactcgat tggtcgtccc ttatatcggc cggctttttg agccaataat actccttacc
     2161 gctgacgttc acgaattttc tcacgctcgt tttgtgcaat ataacttagc agtgataaaa
     2221 acatatcgaa catagcggta tccaggagtt catttccagt attaaaatct aaaaactgtg
     2281 catctaatat ttttaacgct acttttttct gtttcataaa agcaactgta ttttttatat
     2341 cttcataatc tcttcctaaa cgatctagtg atgtaacgat gacgcaatca ccttcacgga
     2401 tataatttag taatttttga aactcaggac gctcagtatc tttaccactg gctttttctt
     2461 ggaataattt atcaatgtta agtccttcca tcattgccaa ttgtcgatcc aaattttgat
     2521 cttgtgaaga tactcgaata tagccaattt ttcccataaa aaactccttt ttaaaagtga
     2581 tataatttac atgtaaaatt tacttgtagt tttactgcta tcaggggtag cgtcaggaaa
     2641 atgcggattt acaacgctaa gcctattttc ctgacgaatc cctcgttttt aacaacgtta
     2701 agaaagtttt agtggtctta aagaatttaa tgagactact ttctctgagt taaaatggta
     2761 ttctcctagt aaattaatat gttcccaacc taagggcgac atatggtgta acaaatcttc
     2821 attaaagcta cctgtccgtt ttttatattc aactgctgtt gttaggtgga gagtattcca
     2881 aatacttata gcattgataa ttatgtttaa agcactggct ctttgcaatt gatgctgtat
     2941 ggtgcgttct ctaagctcac cttgttttcc gaagaaaata gctcttgcca atccattcat
     3001 ggcttctcct ttattcaatc ctctttgtat ttttcttctt aatgattcat ccgatatata
     3061 attcaaaata aagatcgttt tttctattcg gcccatctca cgtaaggctg tagctaagct
     3121 gttttgtctt gaataggaac ctagcttccc cataataagg gatgctgaaa ctgttccctc
     3181 ccttatagaa tgagctaatc gcaaaacatc ctcataattt tctttaatga cctttgtatt
     3241 tatttgtcca cgtaaaatgg cttctagttt tggatactca cttgctttat ctatcgtaaa
     3301 taattttgag tccgataaat cccttattct tggggcaaat ttaaatccta ataaatgagt
     3361 cagtccgaat atttggtcag tgtaaccggc agtgtctgta taatgttcct ctatgtttag
     3421 atccgtctca tgatgtaaca aaccatccaa aacatgaatc gcatctcttg aattagtatg
     3481 aataatcttt gtgtagtaag aagagaattg atcacttgta aatcggtaga tggtggctcc
     3541 ttttccagtt ccataatgtg gatttgcatc tgcatgtagt gatgaaacac ctagctgcat
     3601 tctcatacca tctgacgaag atgttgtacc gtcgccccaa tagaaaggca attgtaattt
     3661 atgatgaaag tttactaata tggcttgggc tttattcatg gcatcttcat acatgcgcca
     3721 ttgagataca ttggctagtt gcttatatgt aagtccgggt gtggcttcgg ccatcttgct
     3781 caagccaata ttcattccca ttcctaaaag ggcagccatg ataatgattg tttcttcctt
     3841 atctggtttt cgattattgg aagcatgagt gaattgctca tgaaatcctg ttatatgggc
     3901 cacatccatg agtaaatcag ttaattttat tcttggtagc atctgataaa ggcttgcact
     3961 aaattttttt gcttcttctg gaacatcttt ttctaagcgt gcaagtgata gctttccttt
     4021 ttcaagagaa accccatcta acttattgga attggcagct aaccacttta acctttcatt
     4081 aaagctgctg gttctctccg ttatataatc ttcgaatgat aaactaactg ataatctcgt
     4141 attccccttc gattgattcc atgtatcttc cgaaaacaaa tattcctcaa aatccctata
     4201 ttgtctgctg ccaacaatgg aaacatctcc tgcccgaaca tgctcccgaa gttctgttaa
     4261 aacagccatt tcatagtaat gacgattaat tgttgtacca tcatcctcgt ataaatgtct
     4321 tttccatcgt tttgaaataa aatccacagg tgagtcatca ggcacttttc gctttccaga
     4381 ttcgttcatt cctcggataa tctcaacagc ttgtaaaagt ggctcatttg cctttgtaga
     4441 atgaaattcc aatactctta atagcgttgg cgtatatttt cttagtgaat aaaaccgttt
     4501 ttgcagtaag tctaaataat catagtcggc aggacgtgca agttcctgag cctcttctac
     4561 tgaagagaca aaggtattcc attcaataac cgattctaaa accttaaaaa cgtctaattt
     4621 ttcctctctt gctttaatta atgcttgtcc gatgttcgta aagtgtataa ctttctcatt
     4681 tagcttttta ccgttttgtt tctggatttc ctcttgagcc ttacgacctt ttgataacaa
     4741 actaagtatt tgcctatcat gaatttcaaa cgctttatcc gttagctcct gagtaagttg
     4801 taataaatag atggttaata tcgaataacg tttattttct tgaaagtcac ggaatgcata
     4861 cggctcgtat cttgagccta agcgagacag ctgcaacagg cggttacggt gcaaatgact
     4921 aatttgcact gtttctaaat ccattcctcg tatgtattcg agtcgttcta ttatttttag
     4981 aaaagtttcg ggtgaaggat gacccggtgg ctcttttaac caacccaata tcgttttatt
     5041 ggattcggat ggatgctgcg aggtaataat cccttcaagc ttttcttttt gctcatttgt
     5101 tagagattta ctaaccgtat taaatagctt cttttcagcc attgcccttg cttcccacac
     5161 cattctttca agtgtagtga tagcaggcag tataattttg ttttttctta gaaaatctat
     5221 gcattcatgc agtagatgaa tggcatcacc attttccaaa gctaattgat gaaggtactt
     5281 aaatgtcatt cgatattcac tcagggtaaa agttacaaag tcgtattcac ttcgaatttc
     5341 tttcaaatga tcccaaagtg tattttccct ttgaggataa tgatcaagcg aggatggact
     5401 aacaccaatc tgtttcgata tatattgtat gaccgaatct gggatgcttt tgatatgagt
     5461 gtatggccaa ccgggatacc gaagaacagc taattgaaca gcaaatccta aacggttttc
     5521 ttccctcctt cgcttattaa ctatttctaa atcccgtttg gaaaaagtga agtaggtccc
     5581 cagtatccat tcatcttcag ggatttgcat aaaagcctgt ctctgttccg gtgtaagcaa
     5641 ttctctacct ctcgcaattt tcattcagta tcattccatt tctgtatttt caatttatta
     5701 gttcaattat atatcaatag agtgtactct attgatacaa atgtagtaga ctgataaaat
     5761 catagttaag agcgtctcat aagacttgtc tcaaaaatga ggtgatattt tgcggaaaat
     5821 cggttatatt cgtgtcagtt cgactaacca gaatccttca agacaatttc agcagttgaa
     5881 cgagatcgga atggatatta tatatgaaga gaaagtttca ggagcaacaa aggatcgcga
     5941 gcaacttcaa aaagtgttag acgatttaca ggaagatgac atcatttatg ttacagactt
     6001 aactcgaatc actcgtagta cacaagatct atttgaatta atcgataaca tacgagataa
     6061 aaaggcaagt ttaaaatcac taaaagatac atggcttgat ttatcagaag ataatccata
     6121 cagccaattc ttaattactg taatggctgg tgttaaccaa ttagagcgag atcttattcg
     6181 gatgagacaa cgtgaaggga ttgaattggc taagaaagaa ggaaagttta aaggtcgatt
     6241 aaagaagtat cataaaaatc acgcaggaat gaattatgcg gtaaagctat ataaagaagg
     6301 aaatatgact gtaaatcaaa tttgtgaaat tactaatgta tctagggctt cattatacag
     6361 gaaattatca gaagtgaata attagccatt ctgtattccg ctaatgggca atatttttaa
     6421 agaagaaaag gaaactataa aatattaaca gcctcctagc gatgccgaaa agccctttga
     6481 taaaaaaaga atcatcatct taagaaattc ttagtcattt attatgtaaa tgcttataaa
     6541 ttcggcccta taatctgata aattattaag ggcaaactta tgtgaaaggg tgataactat
     6601 gagcgataaa atacttattg tggatgatga acatgaaatt gccgatttgg ttgaattata
     6661 cttaaaaaac gagaattata cggttttcaa atactatacc gccaaagaag cattggaatg
     6721 tatagacaag tctgagattg accttgccat attggacatc atgcttcccg gcacaagcgg
     6781 ccttactatc tgtcaaaaaa taagggacaa gcacacctat ccgattatca tgctgaccgg
     6841 gaaagataca gaggtagata aaattacagg gttaacaatc ggcgcggatg attatataac
     6901 gaagcccttt cgcccactgg agttaattgc tcgggtaaag gcccagttgc gccgatacaa
     6961 aaaattcagt ggagtaaagg agcagaacga aaatgttatc gtccactccg gccttgtcat
     7021 taatgttaac acccatgagt gttatctgaa cgagaagcag ttatccctta ctcccaccga
     7081 gttttcaata ctgcgaatcc tctgtgaaaa caaggggaat gtggttagct ccgagctgct
     7141 atttcatgag atatggggcg acgaatattt cagcaagagc aacaacacca tcaccgtgca
     7201 tatccggcat ttgcgcgaaa aaatgaacga caccattgat aatccgaaat atataaaaac
     7261 ggtatggggg gttggttata aaattgaaaa ataaaaaaaa cgactattcc aaactagaac
     7321 gaaaacttta catgtatatc gttgcaattg ttgtggtagc aattgtattc gtgttgtata
     7381 ttcgttcaat gatccgaggg aaacttgggg attggatctt aagtattttg gaaaacaaat
     7441 atgacttaaa tcacctggac gcgatgaaat tatatcaata ttccatacgg aacaatatag
     7501 atatctttat ttatgtggcg attgtcatta gtattcttat tctatgtcgc gtcatgcttt
     7561 caaaattcgc aaaatacttt gacgagataa ataccggcat tgatgtactt attcagaacg
     7621 aagataaaca aattgagctt tctgcggaaa tggatgttat ggaacaaaag ctcaacacat
     7681 taaaacggac tctggaaaag cgagagcagg atgcaaagct ggccgaacaa agaaaaaatg
     7741 acgttgttat gtacttggcg cacgatatta aaacgcccct tacatccatt atcggttatt
     7801 tgagcctgct tgacgaggct ccagacatgc cggtagatca aaaggcaaag tatgtgcata
     7861 tcacgttgga caaagcgtat cgactcgaac agctaatcga cgagtttttt gagattacac
     7921 ggtataacct acaaacgata acgctaacaa aaacgcacat agacctatac tatatgctgg
     7981 tgcagatgac cgatgaattt tatcctcagc tttccgcaca tggaaaacag gcggttattc
     8041 acgcccccga ggatctgacc gtgtccggcg accctgataa actcgcgaga gtctttaaca
     8101 acattttgaa aaacgccgct gcatacagtg aggataacag catcattgac attaccgcgg
     8161 gcctctccgg ggatgtggtg tcaatcgaat tcaagaacac tggaagcatc ccaaaagata
     8221 agctagctgc catatttgaa aagttctata ggctggacaa tgctcgttct tccgatacgg
     8281 gtggcgcggg acttggattg gcgattgcaa aagaaattat tgttcagcat ggagggcaga
     8341 tttacgcgga aagcaatgat aactatacga cgtttagggt agagcttcca gcgatgccag
     8401 acttggttga taaaaggagg tcctaagaga tgtatataat tttttaggaa aatctcaagg
     8461 ttatctttac tttttcttag gaaattaaca atttaatatt aagaaacggc tcgttcttac
     8521 acggtagact taataccgta agaacgagcc gttttcgttc ttcagagaaa gatttgacaa
     8581 gattaccatt ggcatccccg ttttatttgg tgcctttcac agaaagggtt ggtcttaatt
     8641 atgaataaca tcggcattac tgtttatgga tgtgagcagg atgaggcaga tgcattccat
     8701 gctctttcgc ctcgctttgg cgttatggca acgataatta acgccaacgt gtcggaatcc
     8761 aacgccaaat ccgcgccttt caatcaatgt atcagtgtgg gacataaatc agagatttcc
     8821 gcctctattc ttcttgcgct gaagagagcc ggtgtgaaat atatttctac ccgaagcatc
     8881 ggctgcaatc atatagatac aactgctgct aagagaatgg gcatcactgt cgacaatgtg
     8941 gcgtactcgc cggatagcgt tgccgattat actatgatgc taattcttat ggcagtacgc
     9001 aacgtaaaat cgattgtgcg ctctgtggaa aaacatgatt tcaggttgga cagcgaccgt
     9061 ggcaaggtac tcagcgacat gacagttggt gtggtgggaa cgggccagat aggcaaagcg
     9121 gttattgagc ggctgcgagg atttggatgt aaagtgttgg cttatagtcg cagccgaagt
     9181 atagaggtaa actatgtacc gtttgatgag ttgctgcaaa atagcgatat cgttacgctt
     9241 catgtgccgc tcaatacgga tacgcactat attatcagcc acgaacaaat acagagaatg
     9301 aagcaaggag catttcttat caatactggg cgcggtccac ttgtagatac ctatgagttg
     9361 gttaaagcat tagaaaacgg gaaactgggc ggtgccgcat tggatgtatt ggaaggagag
     9421 gaagagtttt tctactctga ttgcacccaa aaaccaattg ataatcaatt tttacttaaa
     9481 cttcaaagaa tgcctaacgt gataatcaca ccgcatacgg cctattatac cgagcaagcg
     9541 ttgcgtgata ccgttgaaaa aaccattaaa aactgtttgg attttgaaag gagacaggag
     9601 catgaataga ataaaagttg caatactgtt tgggggttgc tcagaggagc atgacgtatc
     9661 ggtaaaatct gcaatagaga tagccgctaa cattaataaa gaaaaatacg agccgttata
     9721 cattggaatt acgaaatctg gtgtatggaa aatgtgcgaa aaaccttgcg cggaatggga
     9781 aaacgacaat tgctattcag ctgtactctc gccggataaa aaaatgcacg gattacttgt
     9841 taaaaagaac catgaatatg aaatcaacca tgttgatgta gcattttcag ctttgcatgg
     9901 caagtcaggt gaagatggat ccatacaagg tctgtttgaa ttgtccggta tcccttttgt
     9961 aggctgcgat attcaaagct cagcaatttg tatggacaaa tcgttgacat acatcgttgc
    10021 gaaaaatgct gggatagcta ctcccgcctt ttgggttatt aataaagatg ataggccggt
    10081 ggcagctacg tttacctatc ctgtttttgt taagccggcg cgttcaggct catccttcgg
    10141 tgtgaaaaaa gtcaatagcg cggacgaatt ggactacgca attgaatcgg caagacaata
    10201 tgacagcaaa atcttaattg agcaggctgt ttcgggctgt gaggtcggtt gtgcggtatt
    10261 gggaaacagt gccgcgttag ttgttggcga ggtggaccaa atcaggctgc agtacggaat
    10321 ctttcgtatt catcaggaag tcgagccgga aaaaggctct gaaaacgcag ttataaccgt
    10381 tcccgcagac ctttcagcag aggagcgagg acggatacag gaaacggcaa aaaaaatata
    10441 taaagcgctc ggctgtagag gtctagcccg tgtggatatg tttttacaag ataacggccg
    10501 cattgtactg aacgaagtca atactctgcc cggtttcacg tcatacagtc gttatccccg
    10561 tatgatggcc gctgcaggta ttgcacttcc cgaactgatt gaccgcttga tcgtattagc
    10621 gttaaagggg tgataagcat ggaaatagga tttacttttt tagatgaaat agtacacggt
    10681 gttcgttggg acgctaaata tgccacttgg gataatttca ccggaaaacc ggttgacggt
    10741 tatgaagtaa atcgcattgt agggacatac gagttggctg aatcgctttt gaaggcaaaa
    10801 gaactggctg ctacccaagg gtacggattg cttctatggg acggttaccg tcctaagcgt
    10861 gctgtaaact gttttatgca atgggctgca cagccggaaa ataacctgac aaaggaaagt
    10921 tattatccca atattgaccg aactgagatg atttcaaaag gatacgtggc ttcaaaatca
    10981 agccatagcc gcggcagtgc cattgatctt acgctttatc gattagacac gggtgagctt
    11041 gtaccaatgg ggagccgatt tgattttatg gatgaacgct ctcatcatgc ggcaaatgga
    11101 atatcatgca atgaagcgca aaatcgcaga cgtttgcgct ccatcatgga aaacagtggg
    11161 tttgaagcat atagcctcga atggtggcac tatgtattaa gagacgaacc ataccccaat
    11221 agctattttg atttccccgt taaataaact tttaaccgtt gcacggacaa actatataag
    11281 ctaactcttt cggcaggaaa cccgacgtat gtaactggtt cttagggaat ttatatatag
    11341 tagatagtat tgaagatgta aggcagagcg atattgcggt cattatctgc gtgcgctgcg
    11401 gcaagatagc ctgataataa gactgatcgc atagaggggt ggtatttcac accgcccatt
    11461 gtcaacaggc agttcagcct cgttaaattc agcatgggta tcacttatga aaattcatct
    11521 acattggtga taatagtaaa tccagtaggg cgaaataatt gactgtaatt tacggggcaa
    11581 aacggcacaa tctcaaacga gattgtgccg tttaagggga agattctaga aatatttcat
    11641 acttccaact atatagttaa ggaggagact gaaaatgaag aagttgtttt ttttattgtt
    11701 attgttattc ttaatatact taggttatga ctacgttaat gaagcactgt tttctcagga
    11761 aaaagtcgaa tttcaaaatt atgatcaaaa tcccaaagaa catttagaaa atagtgggac
    11821 ttctgaaaat acccaagaga aaacaattac agaagaacag gtttatcaag gaaatctgct
    11881 attaatcaat agtaaatatc ctgttcgcca agaaagtgtg aagtcagata tcgtgaattt
    11941 atctaaacat gacgaattaa taaatggata cgggttgctt gatagtaata tttatatgtc
    12001 aaaagaaata gcacaaaaat tttcagagat ggtcaatgat gctgtaaagg gtggcgttag
    12061 tcattttatt attaatagtg gctatcgaga ctttgatgag caaagtgtgc tttaccaaga
    12121 aatgggggct gagtatgcct taccagcagg ttatagtgag cataattcag gtttatcact
    12181 agatgtagga tcaagcttga cgaaaatgga acgagcccct gaaggaaagt ggatagaaga
    12241 aaatgcttgg aaatacgggt tcattttacg ttatccagag gacaaaacag agttaacagg
    12301 aattcaatat gaaacatggc atattcgcta tgttggttta ccacatagtg cgattatgaa
    12361 agaaaagaat ttcgttctcg aggaatatat ggattaccta aaagaagaaa aaaccatttc
    12421 tgttagtgta aatggggaaa aatatgagat cttttattat cctgttacta aaaataccac
    12481 cattcatgtg ccgactaatc ttcgttatga gatatcagga aacaatatag acggtgtaat
    12541 tgtgacagtg tttcccggat caacacatac taattcaagg aggtaaggat ggcggaatga
    12601 aaccaacgaa attaatgaac agcattattg tactagcact tttggggtaa cgttagcttt
    12661 ttaatttaaa acccacgtta actaggacat tgctatacta atgatacaac ttaaacaaaa
    12721 gaattagagg aaattatatt gggaaaaata ttatctagag gattgctagc tttatattta
    12781 gtgacactaa tctggttagt gttattcaaa ttacaataca atattttatc agtatttaac
    12841 agaattaggc agaagtcgcc catcctctat
//
LOCUS       DADVXM010000220        11471 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.guided.081, whole genome shotgun sequence.
ACCESSION   DADVXM010000220 DADVXM010000000
VERSION     DADVXM010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.guided.081"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            40..423
                     /locus_tag="KB927_002835"
                     /pseudo
     CDS             40..423
                     /locus_tag="KB927_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
     gene            737..3724
                     /locus_tag="KB927_002836"
     CDS             737..3724
                     /locus_tag="KB927_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HBB6841669.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMSSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMASADGIRYITPQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSL
                     YLLEGFLNQPSELTPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDAN
                     AHYGELDTLSQNSINMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGK
                     AITEYGKVYKTKHQLRYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYD
                     GMEEQLNALGLVTNAIIYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVG
                     KYTFRYEAELSNGKLRPLNVEEF"
     gene            3961..4185
                     /locus_tag="KB927_002837"
     CDS             3961..4185
                     /locus_tag="KB927_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6841670.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            4200..5069
                     /locus_tag="KB927_002838"
     CDS             4200..5069
                     /locus_tag="KB927_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBB6841671.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5050..5784
                     /locus_tag="KB927_002839"
     CDS             5050..5784
                     /locus_tag="KB927_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6841672.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            5817..6680
                     /locus_tag="KB927_002840"
     CDS             5817..6680
                     /locus_tag="KB927_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003109014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBB6841673.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHLNQILRFELLRMMSWKVGIKTEFSLSVGKNYKYINKYID
                     EDLWNRLLSTYRMDSYENIWKSLFICHQLFREVSKEVAELLGFDYPEYGKNITRYTED
                     MYKKYVENDYF"
     gene            6724..7251
                     /locus_tag="KB927_002841"
     CDS             6724..7251
                     /locus_tag="KB927_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBB6841674.1"
                     /translation="MESTDVINEIRGILPRNSIGKYDLLTIFTHKTVFDKIVKVLSLD
                     FQNKVDYVAAPEAIGWILGTAIAKELGVGFIGVRKGDKLPYAKEEIISTHFTDYSGQD
                     KSFEISKSSIVRNKRVLIVDDWIETGSQMKALIALLEKLDCSIIGLATIGIDINEVTQ
                     KWIDSSFVAYIGSNI"
     gene            7479..8798
                     /locus_tag="KB927_002842"
     CDS             7479..8798
                     /locus_tag="KB927_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSsu5 family transposase"
                     /protein_id="HBB6841675.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGRLSSDSGLVLVKELMNTFGFSH
                     LAKQWLHITDHRAYFTHDNLAILEQLIMQLIAGYSADSSANLLRRDPVFQAVLGKKQL
                     ASQSSISRFLDRFTEENIDQLQALNQSLIDKARLIRNDTELIIDVDSTHSDTFGRQEQ
                     TDYNAHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKAFINPLLHHYKSTLPH
                     TEILVRGDSGFATPEVYESCEATESQYVIRLKSNRRLSQLAEHSVLYGDNQEWEEREV
                     QYFSLPYQAQSWSKPRRVCIRSVREGGELLFHHAFIVTNLSDNVSPEVIFSLYGKRGT
                     MENFIKEAKGGFYFDKTDSPRFLENHVRMMISVLAYNLVNFLKSIGFDKVNQGMTIHS
                     IRLILLKVAGKLVQTGRQVYLKLSSYHVYQTEFYKVFERLRRSKQWI"
     gene            8989..10476
                     /locus_tag="KB927_002843"
     CDS             8989..10476
                     /locus_tag="KB927_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HBB6841676.1"
                     /translation="MNYSGFFEVEASIKVNQGSFKGVLSPTQRFKSQEELLSFVSSKQ
                     AKIGNQEGIIADVQTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYEAKL
                     LSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHHAII
                     PTKQVPTESALAKMDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKVADLLFQSIGK
                     TPKQEGWKILFKQQTKEEKEDVQTLPLVIIGEHAEVDVKSAEKETQPPKAFTEGTLLT
                     AMKTANKTVDDEEAIKILQEVEGIGTEATRASIIEALKQKEYIQVIKNKLVVTEKGKL
                     LCQAVESQHLLTSAEMTAKWETYLKKIGKREGNQENFINNIKKFIVHLLEAVPNDIEK
                     LNFSDYQEQKEKEAEKSIVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFRKKKLT
                     KTNVKELLEGKETLVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            10596..10835
                     /locus_tag="KB927_002844"
     CDS             10596..10835
                     /locus_tag="KB927_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBB6841677.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDMMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            10884..10967
                     /locus_tag="KB927_002845"
     CDS             10884..10967
                     /locus_tag="KB927_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBB6841678.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            11092..11436
                     /locus_tag="KB927_002846"
                     /pseudo
     CDS             11092..11436
                     /locus_tag="KB927_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
BASE COUNT         4047 a         1805 c         2214 g         3405 t
ORIGIN      
        1 aagaaccgtc aggtttagct aagtggtgag tagttcactt atcatcaaag aagtcttaac
       61 ttgactccat ttactgctac tgggaatttc agagagatga tagataatgt tataatcttt
      121 attccatttg gcttgctttt gaatgtcaat tttaaagaaa tcggattttt acctaagttt
      181 gcttttgtac tggttttaag tcttactttt gaaataattc aatttatctt cgctattgga
      241 gcgacagaca taacagatgt aattacaaat actgttggag gctttcttgg actgaaatta
      301 tatggtttaa gcaataagca tatgaatcaa aaaaaattag acagagttat tatttttgta
      361 ggtatacttt tgctcgtatt attgctcgtt taccgtaccc atttaagaat aaattacgtg
      421 taagatgtct aaatcaagca atctgatctt tcatacacat aaagatattg aatgaattgg
      481 attagatgga aaacgggatg tggggaaact cgcccgtagg tgtgaagtga ggggaaaacc
      541 ggtgataaag taaaaagctt acctaacact atagtaacaa agaaagccca attatcaatt
      601 ttagtgctga ggaattggtc tctttaataa atttccttaa cgttgtaaat ccgcattttc
      661 ctgacggtac ccctatcata gcatttttaa aaataaattt tatgtagact taaaatttac
      721 ttcatggagg gtttaaatgg atgaaatcaa aagtaacaaa aaagcatttg gcatttattt
      781 aggagaacct agtacagaac aattaaacca atttttttat ttgcatgaaa aagatttaga
      841 attgatggag actatacgac gaccagctac tagattaggt tttgcactac agttagtctc
      901 actacgtttt ttaggaactt ttatattaga tcttaccaat attccccaaa atgtattgag
      961 ttatgtagca actcaactaa atattgatcc tggagaaatt atctactata gcaggagaca
     1021 gaccaggtat cagcacacaa aattgataaa atcacattat ggatatcaag atttcaacca
     1081 accggaaata gaaacatacc tagctaactg gcttttaaat agagcgctgt atacaacaga
     1141 atcttcagat atgttgtttg atatgcttct aaaaaaatgt ctggatgaaa agattgtttt
     1201 acctggaatt actacttttt ctcgttttgt tgctagtgca attgaaaaag ctgaagagca
     1261 tttataccga caattgtctt tggttccaac tgaagatgag agaaagcggc ttctcaatca
     1321 tttagaatta attggaactc cagtttatgg ggcaataatc aaaatggaca ttttgagaac
     1381 cccgttagct gacgatagtc ataaagaaat agccagaggt tttgaccgac taaagcaatt
     1441 tcaagctttc tctactgaaa aatggaagat ggaatctatt cctgaaggga aaataaaagt
     1501 tcttgcaaat tatgcattta aagctaaagc tcaattaatt caacgaatga gtgaacagaa
     1561 aaaactggcg ttgttagtgg catttatttt catatacaaa cgtaaggcta tggatgaaca
     1621 aattttagca ctatctaatt tttttgaaac tgtttttaga cgcgccaaaa ataaggaatc
     1681 taaagaacgt cttcgtacca taaaagatct agatcgagcc gcatcgacac tttcagatat
     1741 tgtagattta gtaatgtcca gtcattctga tactaatgaa ctatcccttc gcgatcgtat
     1801 cttagaaaaa tattctgagg aaaatgttac cgaagctgta tcgcaagttc ggctattggt
     1861 taaaaatgat cgtgaaccaa tagccatttc tgaacttctg aacacttatc gaaagttcag
     1921 aaaatttatt ccggatattt taactacact aacatttgac agcaatgact acggtaacaa
     1981 ctgtaaggaa ctctggacct tcattaataa tagatttcct aagccgatta cttacaaaat
     2041 gtttggagct attaaacata ctcttccaaa gaaatggatt tattacattc atgaataccc
     2101 tgaacaaact aataaatgtg tattgattgc agctgtcgaa ttgttaattc aatctttaaa
     2161 acgccatgat atttatattc ctcagagtgt cttatataac aatcctatgg attgcttgat
     2221 tgatgagaaa acttgggttc aacaaaaata cgttttatta gaacaactag atcttccttc
     2281 ttcagcaaat gaaatgtctt tatggttaaa gaacgatttg gaactgtctt ataaagaagc
     2341 gctaaatcgt tggcctactt ctaaaatggc cagaatagaa aatgcagatc gcctggttgt
     2401 ctctagactt aaaaagacat atgaaaaaaa ggaagataag tcttttagac gtcgcattca
     2461 gcagttactt cctaaaattg atttgtcaga tttgttattg gaagtaaacc aacagttaaa
     2521 tcttactcaa tcatttaacc acttaagtga caaggacacc aaaatgaaag acttggatat
     2581 tagtttatta gcagttcttt tatcagagtc ctgcaatatt ggtttttccc cggtttcaaa
     2641 agaaggattt gattctttaa agtatgatcg tcttgtctat gtcaatcatc attatattcg
     2701 agtggataca ctttcaggag ctaatcaaaa aataatacat gcacacagga aacttgccac
     2761 ctctaagata tggggtgatg ggcatatggc ttcagctgac ggtattcgtt atatcacacc
     2821 acaacgttcc ctatattcta gaagtaatcc aaaatatttt ggccgtggtc gtgggatcac
     2881 attctacaat tttgtctctg atcaatatat agggttccac ggaatggtcg tttcagggac
     2941 actgcgagat tcgctttacc ttctagaagg attcctcaat caacccagcg aattaactcc
     3001 taatcagatc atgactgata cagctggtta tagcgatatg atttttggtc tctttggctt
     3061 attagggttt caatttagtc caagaattgc caatgataaa ggaaccaaac tttggcgaat
     3121 cgacgctaac gctcactacg gggaacttga tacgttgtct caaaattcaa ttaatatgga
     3181 actgatttat acccattggg aggacattct tagggttgca ggttcgttga aatctggaaa
     3241 agtgaatgca acagaattaa cgaaatctct tcaacggaat gggcaaccca cgcctttagg
     3301 aaaagcaata actgagtatg gaaaagttta taagacgaaa catcagcttc gttatatttc
     3361 tgacgaaata tatgcacggc aaattttaga acaattgaat aagggggaag ctcggcatgc
     3421 cttatgccgt aatatttttt atggacgaaa aggaaaactc taccagactt attatgatgg
     3481 gatggaagag cagctcaatg cattaggatt agttactaat gccatcatat attggaactc
     3541 actgtattta gaaaaagtat ttgaacaaat gaaagctgaa ggattcgact gttccgaaga
     3601 aatgatacgc aggcaatctc cactaattag tgatcacatc aattttgttg gtaagtatac
     3661 gtttagatac gaagctgaat tatccaacgg taagttacgt ccattgaatg tagaagaatt
     3721 ctagcaatgt tcgggttttg catgctaccg cactatttcg tatgactgtt ccagcgaatc
     3781 acttcgaata gaaaaagaga aaaacacgag aacagcgtta aatcaacgtt tcttgtgttt
     3841 ttacttttgt gctaccgcac tatttcgttt ctatgttcca tgtaccccat attttaataa
     3901 ctattgtgtt tatcaaccaa atggtttata atattcttag cgtaaacttg gaggtgctgt
     3961 atgactacgg cagaaatgat taaagaactg tgtgagcaaa tgaatataag tgtttccgaa
     4021 cttgctagac gtattggcca gactccacag aatttcaata aaaaattaca acgagaaaca
     4081 gtaaccttgg atgagttgaa ggccattgct gatgtgctag gtgtcaagtt tgtgcaggca
     4141 tttattttac cagatggaga agaaataaaa atatctaacg aataaaggag gatgtttata
     4201 tggtaggtaa tgttattcaa atagtaacag agaaattatc atctttgcct tttatagaag
     4261 gcatcgtatt agggggctca cgtgcaagag gcacccatac agaaaattct gatatagata
     4321 tcggaatcta ttacaattca gactcatttg acctgacagc gattaatcaa attgctacag
     4381 aattggatga taaaaataga aacaaccttg ttgtgcctcc cggagcgtgg ggtgattgga
     4441 ttaatggcgg cggatggtta tttataaatg ggtatcatgt tgacttgatt ttacgtgata
     4501 taaaacgggt agaacaaata atcaaagata cggagcaagg aattgttact gccaattatc
     4561 agaccgggca tccccatggt tatataagtg caatgtatcg tggagaatta gcgattagta
     4621 aaatactata tgctaagaac gaaagcttat gcgaattaaa aaagcaggca gaaatttacc
     4681 ctactgctct aaagaaaagc ttgatgaact tttttatatt tgaagctgaa ttctctttaa
     4741 tgtttgtaaa agcaaatgcg ggggtagagg ataaatatta tattgcaggc catgtttttc
     4801 gtattatttc atgcttaaat caagtactat ttgcatgtaa taatgcttat tgcattaacg
     4861 aaaagaaagc tataaaactg cttgaaactt ttgaatataa acctgaaaaa tatgccgaaa
     4921 gagttaatca tatttttgaa gtactcggtc tttctctttt tgaatgctac gatatgaccg
     4981 agaaacttta taaagaagtg aatgaaattg tatcggagat aaataacttt ttaaacgagg
     5041 agagttcaga tgaaagaaaa caaatatgat gataatatat tttttcaaaa atacagtcaa
     5101 atgagtcgct cgcagaaagg actggctggt gcgggagaat gggagacttt gaaaaagatg
     5161 ctacctgatt ttaagggtaa gcgtgtgctt gatttaggat gcggctatgg atggcactgt
     5221 atatatgcga tggaaaacgg tgcttcctct gtagtaggtg ttgatatttc tcataaaatg
     5281 ctcgaagtag caaaaggaaa aacccatttt ccacagattg aatatgaatg ctgtgccata
     5341 gaagatgtgg atttcccaga ggagagcttt gatgtaatac taagttcgct tgcgtttcat
     5401 tatgtagcag actatgagaa tttaataaaa aagatatata ggatgctgaa ggctggtggc
     5461 aatttagttt ttacagttga acatcctgtt tttactgctc atggaacaca agactggtat
     5521 tataacgaaa aaggagaaat actgcatttc ccggtggaca attattatta tgagggcaaa
     5581 cggacagcta tgtttttgga agaaaaggtt acaaaatatc atagaacact gaccacatat
     5641 ctaaatacac tgctttcaaa tagttttata ataaatcaga ttgtggagcc acagccgcca
     5701 gagaacatga tggatattcc ggggatggcg gatgaaatgc gacgcccaat gatgctgatt
     5761 gtatcggcaa aaaagaagat gtaataatat agaaaaaata aacgaggagt atgtaaatga
     5821 gatcagaaaa agaaatgatg gatttagtac tttctttagc agaacaggat gaacgtattc
     5881 gaattgtgac ccttgagggg tcacgcgcaa atattaatat acctaaagat gaatttcagg
     5941 attatgatat tacatatttt gtaagtgata tagaaccgtt tatatctaat gatgactggc
     6001 ttaatcaatt tgggaatata ataatgatgc aaaagccgga ggatatggaa ttattcccac
     6061 ctgaagaaaa gggattttcc tatcttatgc tatttgatga ttacaataaa attgatctta
     6121 ccttattgcc cttggaagag ttagataatt acctaaaggg cgataaatta ataaaggttc
     6181 taattgataa agattgtaga attaaaaggg acatagttcc gactgatata gattatcatg
     6241 taagaaagcc aagcgcaagg gagtatgatg attgctgcaa tgaattttgg aatgtaacac
     6301 cttatgttat taaaggattg tgccgcaaag agatactgtt tgcaatcgat catctgaacc
     6361 agattctacg gtttgaacta cttaggatga tgtcgtggaa ggttgggata aagacagaat
     6421 tttcattaag tgttgggaaa aattataagt atattaacaa atacattgat gaagatctat
     6481 ggaatagatt attatctaca tatcgcatgg attcctatga aaatatttgg aagtcattat
     6541 ttatatgcca ccaattgttc agggaagtgt ccaaagaggt agcagaacta ctggggtttg
     6601 attatccaga gtatggtaag aacataacaa gatataccga ggacatgtat aaaaaatatg
     6661 ttgaaaatga ctatttttaa agattagcaa agattattaa ccataagcaa ggggtgtaaa
     6721 tgtatggaaa gtactgatgt tataaatgaa attagaggta tattacctcg taactcaatt
     6781 ggaaaatatg atttactaac tatttttaca cataaaaccg tttttgataa aattgtaaaa
     6841 gtactatcat tggattttca aaataaagta gattatgtgg ctgccccaga agcaattgga
     6901 tggatactag gcactgccat agccaaagaa cttggagtgg ggtttattgg agtaagaaaa
     6961 ggtgataagc tgccatacgc aaaagaagag attatttcga cacattttac cgactattca
     7021 ggtcaagata aaagctttga aatatctaag agttctattg tgaggaacaa aagagttttg
     7081 attgtagatg attggataga gacaggttct caaatgaagg ctttaatagc tttgttagag
     7141 aaattggatt gcagcattat tgggttggct actattggga ttgatataaa tgaggttact
     7201 caaaaatgga tagacagcag ttttgtagct tatattggct caaacatata ataaaccgaa
     7261 agaaaatctt gaatcaaaat tttggatggc gttaatttac aatacaacga aagatgttta
     7321 ccctgaataa ttcatacttt ttaattgaaa ccgtctgaaa ctgcctaacg gcagtctgat
     7381 aattactttt ttagtttcac cccttaagtg atgaaaaaag aaccccattc tgctatggta
     7441 aaggtgacga aaccaaccat aagaaaggag ttcttctcat gactagctta cacaaaaatc
     7501 aagttaaatt caattcaaat atcactattt cacataccgg tggtcgtcta tcaagtgatt
     7561 cggggttagt cctggttaaa gaattaatga ataccttcgg cttttcgcac ttagctaaac
     7621 aatggctcca tattacagat catcgggctt attttaccca tgataactta gcgatattgg
     7681 aacagcttat tatgcaatta attgctggtt actcggcaga ctcatcagct aatctattaa
     7741 gacgggatcc tgtctttcaa gctgtactcg gtaaaaaaca gttggcatca caatcctcaa
     7801 tctcacggtt tctggatcgt ttcaccgagg agaacatcga tcaactccaa gcattaaatc
     7861 agtcattgat tgataaagca cgtttaattc gcaatgacac cgagttaatc attgatgtcg
     7921 attccacaca ttcggatacc tttggacgcc aagaacaaac agattataat gcccattatc
     7981 aaacctacgg ctatcaccca ttagttgcct ttgatggact gaccggagat ttcttaaaag
     8041 ctgaactgcg ttcaggcaat cagtacacat ctaaaggggt aaaagccttt atcaacccgc
     8101 ttttacacca ctacaagagc acgttacctc ataccgagat attggttcgg ggtgacagcg
     8161 gcttcgccac accagaggtg tatgagtctt gtgaagcaac tgaaagccag tacgttatcc
     8221 gattaaagag caatcggagg ttaagtcagt tagctgaaca ttctgttctt tacggggaca
     8281 atcaagaatg ggaagagcga gaagtgcagt atttttcact accttatcaa gcacaatcct
     8341 ggtcgaaacc tcgtcgtgtc tgtatacgct ccgtccgtga aggaggagaa ttgctatttc
     8401 atcatgcgtt tattgtgact aatctatccg acaatgtctc gcctgaagtc atattttctc
     8461 tttacggcaa gcgaggaaca atggaaaatt tcatcaaaga agcgaaaggt ggcttttact
     8521 tcgataaaac agatagcccg cgtttcttag aaaatcatgt cagaatgatg atcagtgtcc
     8581 ttgcatacaa cctcgttaat tttttaaaaa gcattggttt tgataaagtg aaccagggca
     8641 tgacgattca ttccatccgg ctgatattgc ttaaagtagc cggtaaactt gttcagactg
     8701 ggagacaggt ctatctcaaa ctgtcaagtt atcatgtgta tcaaactgaa ttttataagg
     8761 tttttgaacg cctgcggcga tccaaacaat ggatttagac tagttatcac acaaattttt
     8821 taaccgattc tttttcaagg gattcgtctg cccttaaata gacaaataat ttttattatg
     8881 atcttcttcc gtaggcatcc tgttcgaaaa cacattattt tggaagaaag tatctgccta
     8941 atttaaaaat tggcaatttg ttcaaaaaaa caggttaaat ttagagctat gaattattca
     9001 ggttttttcg aggtggaagc tagtataaaa gtaaaccaag ggtcgtttaa gggcgttcta
     9061 agccccacac agcgttttaa gagccaagag gaacttttat cctttgtttc ttctaaacaa
     9121 gctaaaatag gcaatcaaga ggggataatt gctgatgttc aaaccaaaga gaagaaaacg
     9181 aatagtccga gtttgttttc tttaagtagt ttacaatcaa aagtcaatca gctttataaa
     9241 gcgacagcga gccaaacttt aaaagctatg caaggactgt atgaagcaaa attattgagt
     9301 tatccaagaa cagatacacc atttattaca gagaacgaat ttgcttattt aaaagcaaat
     9361 tttggcaaat atagcggttt tttaggactt gatctcgaaa tggttcaaac agagcctaga
     9421 aagcgttatg tggacggtag taaggtacag gaacaccacg ccattatccc aacaaaacaa
     9481 gtacctaccg aatctgcatt agcaaaaatg gacgatttac aacgaaaaat atatgcttta
     9541 gtcgttaaaa cgaccgttgc catgttttta cctgattact tgtatgaaga aaccaagata
     9601 caaacgaaag tagctgattt gctgtttcaa tcgatcggaa agacaccaaa acaagaaggt
     9661 tggaaaattc ttttcaaaca acaaaccaaa gaagaaaaag aggacgttca aacgttaccc
     9721 ttggttatca ttggcgaaca tgccgaggtt gacgttaaga gtgccgaaaa agaaacacaa
     9781 ccaccgaaag cttttacaga gggtacatta ttaactgcta tgaaaaccgc taataaaacg
     9841 gttgatgatg aagaagcaat caagatttta caagaagtcg aggggatcgg aacagaagcg
     9901 acaagagcaa gtattattga agcgttaaaa caaaaagaat atatccaagt gattaagaat
     9961 aagcttgttg taactgaaaa aggaaaatta ttgtgccagg cagttgaaag tcagcacctt
    10021 ttaacgagtg ctgaaatgac ggctaaatgg gaaacgtatt taaaaaaaat cggtaaaaga
    10081 gaaggcaatc aagaaaactt tattaataat atcaagaagt ttatcgttca tttactggaa
    10141 gctgtaccta acgatataga aaaactaaat ttttctgatt accaggaaca gaaagaaaaa
    10201 gaagctgaaa aaagtattgt aggaaaatgt cctaagtgtg gcaacaatat tgtattaaaa
    10261 aaatcgtttt atggttgttc aaattatcct gaatgtaagt ttactttagc tgaacatttt
    10321 agaaagaaaa aactaaccaa aacgaatgta aaagaattac tggagggaaa agaaaccctg
    10381 gtaaaaggaa tcaaaaacaa agagaaaaag ccctacaatg ccgttgtaaa aatcggagaa
    10441 aagggatata ttgattttat ctctttctca aaataaacat aaaagccctt taaacagggc
    10501 ttttatatat taatcacaaa tcacctatca caaatcacaa atcacttgcg atttgtgatg
    10561 ataaaataag agtaagaaga aatagaaaga agtgagtgat tgtgggaaat ttaggcgcac
    10621 aaaaagcaaa acgaaatgat acaccaatca gtgcaaaaaa agatatgatg ggagataaga
    10681 cggttcgtgt tcgtgctgac ttgcaccata tcataaaaat cgaaacagca aagaatggcg
    10741 gaaacgtaaa agaagttatg gaaataagac ttagaagcaa acttaagagt gtgttgatag
    10801 tgcattatct taaaattttg tataatagga attgaagtta aattagatgc taaaaatttg
    10861 taattaagaa ggagggattc gtcatgttgg tattccaaat gcgtaatgta gataaaacat
    10921 ctactgtttt gaaacagact aaaaacagtg attacgcaga taaataaata cgttagatta
    10981 attcctacca gtgactaatc ttatgacttt ttaaacagat aactaaaatt acaaacaaat
    11041 cgtttaactt ctgtatttat ttatagatgt aatcacttca ggagtgatta catgaacaaa
    11101 aatataaaat attctcaaaa ctttttaacg agtgaaaaag tactcaacca aataataaaa
    11161 caattgaatt taaaagaaac cgataccgtt tacgaaattg gaacaggtaa agggcattta
    11221 acgacgaaac tggctaaaat aagtaaacag gtaacgtcta ttgaattaga cagtcatcta
    11281 ttcaacttat cgtcagaaaa attaaaactg aacattcgtg tcactttaat tcaccaagat
    11341 attctacagt ttcaattccc taacaaacag aggtataaaa ttgttgggaa tattccttac
    11401 catttaagca cacaaattat taaaaaagtg gtttttggat aaagtccgta taattgtgta
    11461 aaagtaaaaa g
//
LOCUS       DADVXM010000221         7959 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.guided.103, whole genome shotgun sequence.
ACCESSION   DADVXM010000221 DADVXM010000000
VERSION     DADVXM010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.guided.103"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            128..1564
                     /locus_tag="KB927_002847"
     CDS             128..1564
                     /locus_tag="KB927_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6841679.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="KB927_002848"
     CDS             1753..4200
                     /locus_tag="KB927_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBB6841680.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="KB927_002849"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="KB927_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBB6841681.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="KB927_002850"
     CDS             complement(5690..6793)
                     /locus_tag="KB927_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6841682.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="KB927_002851"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="KB927_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBB6841683.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2664 a         1359 c         1729 g         2207 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacatat ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattactt
//
LOCUS       DADVXM010000222         4668 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.guided.122, whole genome shotgun sequence.
ACCESSION   DADVXM010000222 DADVXM010000000
VERSION     DADVXM010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4668
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.guided.122"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..212
                     /locus_tag="KB927_002852"
     CDS             <1..212
                     /locus_tag="KB927_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBB6841684.1"
                     /translation="ELEQEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYSST
                     HRGPSELCGNVFKIEYTKKRQRLAY"
     gene            447..683
                     /locus_tag="KB927_002853"
     CDS             447..683
                     /locus_tag="KB927_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841685.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            690..2642
                     /locus_tag="KB927_002854"
     CDS             690..2642
                     /locus_tag="KB927_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBB6841686.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2714..3211)
                     /gene="dfrG"
                     /locus_tag="KB927_002855"
     CDS             complement(2714..3211)
                     /gene="dfrG"
                     /locus_tag="KB927_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBB6841687.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3573..4613
                     /locus_tag="KB927_002856"
     CDS             3573..4613
                     /locus_tag="KB927_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBB6841688.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
BASE COUNT         1628 a          752 c          837 g         1451 t
ORIGIN      
        1 tggaactcga acaagaggaa agcataagat ttcagaattg ttctctgttc cctctttatc
       61 atggaagtgc aaaaagtaat atagggattg ataaccttat agaagttatt actaataaat
      121 tttattcatc aacacatcga ggtccgtctg aactttgcgg aaatgttttc aaaattgaat
      181 atacaaaaaa aagacaacgt cttgcatatt aagtagttca gttttggagt acaaaaagtg
      241 aaaatgtaaa cctaaatgag tatcaaattg caactgaatt tgatactcgt tttttattgt
      301 taaatcaacg tttgttgtta atttacacca caaaatgtaa gttaaaatgt atataaaaat
      361 gcgaacgtga aataattatt gtaggaatgc aaattggtgt gttaaaatgg ttacaattta
      421 ctaagcaaaa aggggtgcat tttcctatgc aatttcttga gccaaaaaat aagaacgcta
      481 agtctgtgga ttgggaaata tcagagcaag taagggtgat agttaagcaa tacgctgaat
      541 atgcagagcg tactgaaagc gaagcagtgg atgaattctt attgaacatt ttagacgata
      601 agaagtttat tgaatggatt gccaacaagc gaagtaataa gcggattgtt gaaaaaatgg
      661 gtatcaaaga tagagtgggt tgatagacaa tgaccaagct taaaagatta gccacgaagg
      721 aagatgaaat tgtagatgtt aaaattccga tttcaaacga agaattaaaa gatagggcta
      781 aacaatatga tttattaact ccaaaacgat ttgcaacaag gtataacaaa atgttgttct
      841 tgccaacgtc ttttaaatgg aacggttctg aatatcccat tcaatataat tactgcatca
      901 atccgttttg ttgtaatttt gggaaagaac agcacaaatt caaagatgta aaagggaaac
      961 caagtcgata taaaatgact ggtagttcca aagataaagg tcataaaggt atgtactgca
     1021 atgacaatcc tattggcaga ggtgtatcgc aaaactgtac agtaacccct ttatctaatt
     1081 ggtctgttgt tgaagaaatt aaacgcctta tagaaatcaa tagcatccaa gatgttgagc
     1141 cagattatca atttcataaa gaaggctgct cggaagaaga atcaacccca ttcaatgagc
     1201 cgaagcaatt ttacaaaagg gggaaaagta ggggcaaatc tcaacgctat caatgtaagg
     1261 cgtgtaagaa gttcactaat gttctaccaa aaagagaaga aaccactact tatcaccaac
     1321 aaaagaacac cattcttcca atgttcgcta agatggttgt tggaagggtt tcagtcagtc
     1381 gtacttgtga tattttagga attggagttg gaacctacta tcataagctg gagtggctgt
     1441 ataggcgttg tttggagttt ttagaacgat atgagacaca accccttcaa acaaagaaat
     1501 ttaacgagat gtggcttaat acggacaaga tgcactacta cctaaataac gtccgtaaga
     1561 aaggacaagg ttcaaagaaa tatacggggt ttgaagacct taatatgcaa acgtatatag
     1621 ttgtatctgc tgaggtctta tcaagatatg tgttccgttc tgatgttgcc tatgattgga
     1681 atatttcaat ggatgaatta aatgaagata caagaaaatt caaagaagac catctcaata
     1741 cttttagtcg taaaaatgat aggttagatt ggtcttatta tccacaagaa ccatccgcta
     1801 acgatagcga aaataggaat gcttatcttc acgaattagg gaaaattact aataggagta
     1861 gatttgtcga tggtttaaat gttgatgctc cttatactac aactgctcac tattggttaa
     1921 ttaaacaaat ggttaatgcc gacgaatggc gaatgattag tgatgatgac ttctctatta
     1981 gaaacgcctt ttatagagta ttcacgaaag aattaaggtt gagcgatgca catcatttta
     2041 tttgccaagt taacaagacg aaaagcagaa aacaatgctt aaaagaattc ggacaagcaa
     2101 aagcagaact gctcgattgg ggagatatca gaggattcaa aacaaagttt ctacggactt
     2161 tggcatctca ttatctaact gaattactaa caagtcatca attccacgaa gaggctatta
     2221 gtaaagatgg agaaagatat cgcaaatatg ccgataaccc tatcaaacat ccattagcca
     2281 ctaaggataa aggattttat tcagttgatt gtagaacgga tttatctgct ctggaaccaa
     2341 acgaaatcgc aaagatgcta ttaaatgtta atgaccattc gaccaatagc tttattcaac
     2401 agataagacg ttatatatca tctcttgaaa gaccattaac aacagctcgt ggtgataaga
     2461 agagctatat ttacgctaac ttcaatccga agtatgctca atttgcgatt acaattctaa
     2521 gaacttacta caacttttgt cgccctttta aatcagcgga taaaaaggtt ttgacacctg
     2581 ctcaaagatt agggattaca gataaacaat ttgattggaa agatataatt tatttcaaat
     2641 gacaaaaaga gcttggagta atcccaagct cttgtgcttt atctttactg ttcttcttca
     2701 attaacgcac ccgttaactc aataagtttt ttctttcata tacatgaaaa tagtagttat
     2761 acggattttt atcattcttt atcccttttt gggcaaatac ctcattccat tcctcataat
     2821 tcacttctgg aaaaaaagta tctccttcga attcatgatg tatttttgtg atgtacattt
     2881 tctcaacata agggaaaaac aaattataaa tctgttctcc tccgaaaata aaaatttctt
     2941 cttcgttttt acataactca aaaacatctt ctattgaatg aacaatttca caaccattaa
     3001 aggtaaaccc cttatctctc gtcagaataa tatttcttct gtcaggtaag gctcttccga
     3061 ttgattcaag gttcttccta cctaatatta tcggatgtcc ctttgtagta tttttaacat
     3121 attcccagtc cttgggaatc ctccaaggaa tgtcattctc tttgccaatc actctattct
     3181 tatccatcgc agcaatcaaa gaaactttca tttataacac agccttttta actaatttac
     3241 catctaattt cttatttcta tcaaaaaacc ttttctcatt atcctgcccg ttagttgaat
     3301 aagcaatttt ttctataagt tatattatca taataccaca aaatcacaaa ttttcattca
     3361 attatcattt tcaattgcat tttataaatc attttgtatg taatttggta tgtaagttaa
     3421 aatgaaaaaa gtagtccatt ttgaagtaca ttttgtcatt ttgtactcca aaactgaact
     3481 acttacttgc atatatacgc ctttatagtg gagtactaca tttacgagat tcggttagag
     3541 tatcagaaaa agaaaaaata aaagttacag aaatgtatac ttcaataaat ggtgaattat
     3601 gtaagattga tagagcttat tctggagaaa ttgttatttt gcaaaatgag tttttgaagt
     3661 taaatagtgt tcttggagat acaaaactat tgccacagag aaaaaagatt gaaaatccgc
     3721 accctctact acaaacaact gttgaaccga gtaaacctga acagagagaa atgttgcttg
     3781 atgccctttt ggaaatctca gatagtgatc cgcttctacg atattacgtg gattctacga
     3841 cacatgaaat tatactttct ttcttaggga aagtacaaat ggaagtgatt agtgcactgt
     3901 tgcaagaaaa gtatcatgtg gagatagaac taaaagagcc tacagtcatt tatatggaga
     3961 gaccgttaaa aaatgcagaa tataccattc acatcgaagt gccgccaaat cctttctggg
     4021 cttccattgg tttatctgta tcaccgcttc cgttgggaag tggaatgcag tatgagagct
     4081 cggtttctct tggatactta aatcaatcat ttcaaaatgc agttatggaa gggatacgct
     4141 atggttgcga acaaggatta tatggttgga atgtgacgga ttgtaaaatc tgttttaagt
     4201 acggtttata ctatagccct gttagtactc cagcagattt tcggatgctt actcctattg
     4261 tactggagca agcctttaga aaagctggaa cagaattgtt agagccatat cttagtttta
     4321 aagtttatgc accacaggaa tatctttcac gggcatataa cgatgctccc aaatattgtg
     4381 caaatatcgt aaatactcaa ctgaaaaata atgaggtcat tattattgga gaaattcctg
     4441 ctcgatgtat tcaagattat cgcaatgatt taactttttt tacaaatggg cttagtgttt
     4501 gtttagcaga gctaaaagga tatcaggtta ccactggcga acctgtttgc cagacccgtc
     4561 gtctaaatag tcggatagat aaagtaagat atatgttcaa taaaataact tagtgcgttt
     4621 tatgttgtta tataaatatg gtttcttatt aaataagatg aaatattc
//
LOCUS       DADVXM010000223         2584 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.guided.148, whole genome shotgun sequence.
ACCESSION   DADVXM010000223 DADVXM010000000
VERSION     DADVXM010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.guided.148"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="KB927_002857"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="KB927_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBB6841689.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..>2584
                     /locus_tag="KB927_002858"
     CDS             2039..>2584
                     /locus_tag="KB927_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6841690.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVP"
BASE COUNT          851 a          403 c          535 g          795 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccg
//
LOCUS       DADVXM010000224         2584 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.guided.149, whole genome shotgun sequence.
ACCESSION   DADVXM010000224 DADVXM010000000
VERSION     DADVXM010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.guided.149"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="KB927_002859"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="KB927_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBB6841691.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..>2584
                     /locus_tag="KB927_002860"
     CDS             2039..>2584
                     /locus_tag="KB927_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6841692.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVP"
BASE COUNT          850 a          403 c          536 g          795 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccg
//
LOCUS       DADVXM010000225         2360 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.guided.154, whole genome shotgun sequence.
ACCESSION   DADVXM010000225 DADVXM010000000
VERSION     DADVXM010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.guided.154"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            <1..331
                     /locus_tag="KB927_002861"
     CDS             <1..331
                     /locus_tag="KB927_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6841693.1"
                     /translation="AGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNE
                     VILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVR
                     YMFNKIT"
     gene            429..1802
                     /gene="tet(L)"
                     /locus_tag="KB927_002862"
     CDS             429..1802
                     /gene="tet(L)"
                     /locus_tag="KB927_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HBB6841694.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT          696 a          360 c          478 g          826 t
ORIGIN      
        1 agctggaaca gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata
       61 tctttcacga gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt
      121 gaaaaataat gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg
      181 tagtgattta actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta
      241 ccatgttact accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa
      301 agtacgatat atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt
      361 ttcttgttaa ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg
      421 aattaattat gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc
      481 tttgcgtttt atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg
      541 atattgcaaa tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta
      601 tgttaacctt ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca
      661 aaaggttact cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg
      721 gccattcttt cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg
      781 catttccagc actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta
      841 aagcatttgg tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg
      901 gtggaatgat agcccattat attcattggt cctatcttct actcattcct atgataacaa
      961 ttatcactgt tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt
     1021 ttgatatcaa aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa
     1081 catcatatag catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac
     1141 atatcaggaa agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta
     1201 tgattggagt tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg
     1261 ttccttatat gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta
     1321 ttttccctgg aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata
     1381 gaagaggtcc tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa
     1441 ctgcttcctt tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt
     1501 taggtgggct ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac
     1561 agcaggaagc tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa
     1621 caggtattgc aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac
     1681 ctatggaagt tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa
     1741 tcattgtcat tagttggctg gttaccttga atgtatataa acattctcaa agggatttct
     1801 aaatcgttaa gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg
     1861 aattcaaatc tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc
     1921 tctcttgtat cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca
     1981 ataaaaattt tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata
     2041 aaaattggca agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc
     2101 tgtcccttgc tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag
     2161 agggcaggtt tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat
     2221 ggttttggtc ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata
     2281 gtgtgttata ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg
     2341 ccacctaaaa aggagcgatt
//
LOCUS       DADVXM010000226         1998 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303236-19
            SAMEA8426461-rid11941583.guided.161, whole genome shotgun sequence.
ACCESSION   DADVXM010000226 DADVXM010000000
VERSION     DADVXM010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426461
            Sequence Read Archive: ERR5555426
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005874.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005874.1
            Genome Coverage       :: 271x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:54:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,864
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,741
            CDSs (with protein)               :: 2,741
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 31 of 65
            Pseudo Genes (incomplete)         :: 24 of 65
            Pseudo Genes (internal stop)      :: 20 of 65
            Pseudo Genes (multiple problems)  :: 8 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426461-rid11941583.guided.161"
                     /isolate="303236-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-06"
     gene            47..439
                     /locus_tag="KB927_002863"
     CDS             47..439
                     /locus_tag="KB927_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6841695.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            440..1879
                     /locus_tag="KB927_002864"
     CDS             440..1879
                     /locus_tag="KB927_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HBB6841696.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          832 a          153 c          342 g          671 t
ORIGIN      
        1 aacattgtat agcattttac acaggagtct ggacttgact gagtttatgg aagaagtttt
       61 aattgatgat aatatggttt ttgatattga taatttaaaa ggatttctta atgataccag
      121 ttcatttggg tttatagcta aagaaaataa taaaattata ggatttgcat attgctatac
      181 acttttaaga cctgatggaa aaacaatgtt ttatttacac tcaataggaa tgttacctaa
      241 ctatcaagac aaaggttatg gttcaaaatt attatctttt attaaggaat attctaaaga
      301 gattggttgt tctgaaatgt ttttaataac tgataaaggt aatcctagag cttgccatgt
      361 atatgaaaaa ttaggtggta aaaatgatta taaagatgaa atagtatatg tatatgatta
      421 tgaaaaaggt gataaataaa tgaatatagt tgaaaatgaa atatgtataa gaactttaat
      481 agatgatgat tttcctttga tgttaaaatg gttaactgat gaaagagtat tagaatttta
      541 tgatggtaga gataaaaaat atacattaga atcattaaaa aaacattata cagagccttg
      601 ggaagatgaa gtttttagag taattattga atataacaat gttcctattg gatatggaca
      661 aatatataaa atgtatgatg agttatatac tgattatcat tatccaaaaa ctgatgagat
      721 agtctatggt atggatcaat ttataggaga gccaaattat tggagtaaag gaattggtac
      781 aagatatatt aaattgattt ttgaattttt gaaaaaagaa agaaatgcta atgcagttat
      841 tttagaccct cataaaaata atccaagagc aataagggca taccaaaaat ctggttttag
      901 aattattgaa gatttgccag aacatgaatt acacgagggc aaaaaagaag attgttattt
      961 aatggaatat agatatgatg ataatgccac aaatgttaag gcaatgaaat atttaattga
     1021 gcattacttt gataatttca aagtagatag tattgaaata atcggtagtg gttatgatag
     1081 tgtggcatat ttagttaata atgaatacat ttttaaaaca aaatttagta ctaataagaa
     1141 aaaaggttat gcaaaagaaa aagcaatata taatttttta aatacaaatt tagaaactaa
     1201 tgtaaaaatt cctaatattg aatattcgta tattagtgat gaattatcta tactaggtta
     1261 taaagaaatt aaaggaactt ttttaacacc agaaatttat tctactatgt cagaagaaga
     1321 acaaaatttg ttaaaacgag atattgccag ttttttaaga caaatgcacg gtttagatta
     1381 tacagatatt agtgaatgta ctattgataa taaacaaaat gtattagaag agtatatatt
     1441 gttgcgtgaa actatttata atgatttaac tgatatagaa aaagattata tagaaagttt
     1501 tatggaaaga ctaaatgcaa caacagtttt tgagggtaaa aagtgtttat gccataatga
     1561 ttttagttgt aatcatctat tgttagatgg caataataga ttaactggaa taattgattt
     1621 tggagattct ggaattatag atgaatattg tgattttata tacttacttg aagatagtga
     1681 agaagaaata ggaacaaatt ttggagaaga tatattaaga atgtatggaa atatagatat
     1741 tgagaaagca aaagaatatc aagatatagt tgaagaatat tatcctattg aaactattgt
     1801 ttatggaatt aaaaatatta aacaggaatt tatcgaaaat ggtagaaaag aaatttataa
     1861 aaggacttat aaagattgat tatataatat atgaaaagct attataaaag acattagtat
     1921 taaatagttt aaaaaaatga aaaataataa aggaagtgag tcaagtccag actcctgtgt
     1981 aaaatgctat acaatgtt
//
